Guide to the Human Genome
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Search of human proteins with 190341104

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|190341104 tripartite motif protein 9 isoform 1 [Homo
sapiens]
         (710 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]     1469   0.0  
gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]      1105   0.0  
gi|134288906 tripartite motif-containing 67 [Homo sapiens]            978   0.0  
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]   201   1e-51
gi|223890259 midline 2 isoform 2 [Homo sapiens]                       197   4e-50
gi|148833499 midline 1 [Homo sapiens]                                 193   5e-49
gi|4557753 midline 1 [Homo sapiens]                                   193   5e-49
gi|15451852 midline 1 [Homo sapiens]                                  193   5e-49
gi|223890257 midline 2 isoform 1 [Homo sapiens]                       186   5e-47
gi|47174859 tripartite motif-containing 46 [Homo sapiens]             177   3e-44
gi|89886468 fibronectin type III and SPRY domain containing 1-li...   103   4e-22
gi|223718222 fibronectin type III and SPRY domain containing 1-l...   103   4e-22
gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]            91   4e-18
gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]       86   9e-17
gi|13236585 fibronectin type III and SPRY domain containing 1 [H...    86   1e-16
gi|124487387 ring finger protein 207 [Homo sapiens]                    81   4e-15
gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]            75   3e-13
gi|62241003 cardiomyopathy associated 5 [Homo sapiens]                 72   2e-12
gi|55741632 fibronectin type III and SPRY domain containing 2 [H...    72   2e-12
gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]    70   7e-12
gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]    70   7e-12
gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]    70   7e-12
gi|54792146 tripartite motif-containing 47 [Homo sapiens]              69   2e-11
gi|52487176 tripartite motif-containing 37 protein [Homo sapiens]      65   2e-10
gi|15147333 tripartite motif-containing 37 protein [Homo sapiens]      65   2e-10
gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]    63   8e-10
gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]    63   8e-10
gi|15208643 ADP-ribosylation factor domain protein 1 isoform gam...    62   1e-09
gi|15208641 ADP-ribosylation factor domain protein 1 isoform bet...    62   1e-09
gi|4502197 ADP-ribosylation factor domain protein 1 isoform alph...    62   1e-09

>gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]
          Length = 710

 Score = 1469 bits (3804), Expect = 0.0
 Identities = 710/710 (100%), Positives = 710/710 (100%)

Query: 1   MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY 60
           MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
Sbjct: 1   MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY 60

Query: 61  DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV 120
           DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
Sbjct: 61  DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV 120

Query: 121 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV 180
           PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
Sbjct: 121 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV 180

Query: 181 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY 240
           MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
Sbjct: 181 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY 240

Query: 241 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN 300
           CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
Sbjct: 241 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN 300

Query: 301 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL 360
           MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
Sbjct: 301 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL 360

Query: 361 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS 420
           RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
Sbjct: 361 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS 420

Query: 421 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD 480
           PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
Sbjct: 421 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD 480

Query: 481 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAF 540
           DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAF
Sbjct: 481 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAF 540

Query: 541 DPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVAR 600
           DPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVAR
Sbjct: 541 DPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVAR 600

Query: 601 MDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKNLTF 660
           MDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKNLTF
Sbjct: 601 MDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKNLTF 660

Query: 661 FINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLPVPDFYSSRASIA 710
           FINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLPVPDFYSSRASIA
Sbjct: 661 FINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLPVPDFYSSRASIA 710


>gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]
          Length = 550

 Score = 1105 bits (2859), Expect = 0.0
 Identities = 534/534 (100%), Positives = 534/534 (100%)

Query: 1   MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY 60
           MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY
Sbjct: 1   MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY 60

Query: 61  DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV 120
           DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV
Sbjct: 61  DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV 120

Query: 121 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV 180
           PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV
Sbjct: 121 PRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATV 180

Query: 181 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY 240
           MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY
Sbjct: 181 MCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMY 240

Query: 241 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN 300
           CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN
Sbjct: 241 CVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN 300

Query: 301 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL 360
           MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL
Sbjct: 301 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL 360

Query: 361 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS 420
           RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS
Sbjct: 361 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNS 420

Query: 421 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD 480
           PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD
Sbjct: 421 PLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELD 480

Query: 481 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSE 534
           DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSE
Sbjct: 481 DGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSE 534


>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
          Length = 783

 Score =  978 bits (2528), Expect = 0.0
 Identities = 493/782 (63%), Positives = 570/782 (72%), Gaps = 95/782 (12%)

Query: 4   MEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESES--PQ------------- 48
           MEEELKCPVCGS +REPIILPCSHN+C  CAR I VQTP+ E   PQ             
Sbjct: 1   MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPDGEQHLPQPLLLSRGSGLQAG 60

Query: 49  -------SHRAA------GSGVSDYDYLD---------LDKMSLYSEADSGYGSYGGFAS 86
                   H AA      G+G S    L           DK+SLYSE DSGYGSY     
Sbjct: 61  AAAAASLEHDAAAGPACGGAGGSAAGGLGGGAGGGGDHADKLSLYSETDSGYGSY----- 115

Query: 87  APTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV-----PRNSCITCPQCHRSLILDDRG 141
              TP  KSPNGVRV P    PP +  + A           +S ITCPQCHRS  LD RG
Sbjct: 116 ---TPSLKSPNGVRVLPMVPAPPGSSAAAARGAACSSLSSSSSSITCPQCHRSASLDHRG 172

Query: 142 LRGFPKNRVLEGVIDRYQQSK---------AAALKCQLCEKAPKE-ATVMCEQCDVFYCD 191
           LRGF +NR+LE ++ RYQQ +         AA   CQLC++ P E A  +CEQCDV YC 
Sbjct: 173 LRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCS 232

Query: 192 PCRLRCHPPRGPLAKHRLVPP-----------------AQGRVSRR-------------- 220
            C+L+CHP RGP AKHRLV P                 AQG  S                
Sbjct: 233 ACQLKCHPSRGPFAKHRLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGAT 292

Query: 221 --LSPRKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLS 278
              + RK  TC +HE+EN+SMYCV C+ PVCY CLEEG+H+ HEVK LGAMWK HK+QLS
Sbjct: 293 GGSTARKFPTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLS 352

Query: 279 QALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARV 338
           QALNG+SD+AKEAKEFLVQL+N++QQIQEN +++EACLVAQCDAL+DAL R+KA+LL +V
Sbjct: 353 QALNGVSDKAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKV 412

Query: 339 NKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTED 398
            KE EHKLK+V DQI+HCT+KLRQ+TGLMEYCLEVIKENDPSGFLQISDALI+RV ++++
Sbjct: 413 TKEREHKLKMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQE 472

Query: 399 QWGKGTLTPRMTTDFDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSA 458
           QW KG L P+++ +FDL+LD+ PLLQ+IHQLDF+Q+K    VP  P+LQLE+CCT NNS 
Sbjct: 473 QWVKGALEPKVSAEFDLTLDSEPLLQAIHQLDFIQMKCR--VPPVPLLQLEKCCTRNNSV 530

Query: 459 TLSWKQPPLSTVPADGYILELDDGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNK 518
           TL+W+ PP +  P DGYILELDDG GGQFREVYVGKET+CT+DGLHFNSTYNARVKAFN 
Sbjct: 531 TLAWRMPPFTHSPVDGYILELDDGAGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNS 590

Query: 519 TGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGI 578
           +GV PYSKT+VLQTS+VAWF FDP S H DIILSNDN T TCSSYDDRVVLG   FSKG+
Sbjct: 591 SGVGPYSKTVVLQTSDVAWFTFDPNSGHRDIILSNDNQTATCSSYDDRVVLGTAAFSKGV 650

Query: 579 HYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTE 638
           HYWEL VDRYDNHPDPAFGVAR  V+KD+MLGKDDKAWAMYVDNNRSWFMH NSHTNRTE
Sbjct: 651 HYWELHVDRYDNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMHCNSHTNRTE 710

Query: 639 GGITKGATIGVLLDLNRKNLTFFINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLP 698
           GG+ KGAT+GVLLDLN+  LTFFIN +QQGP AF +V+G+F PA+SLNRNVQVTLHTGL 
Sbjct: 711 GGVCKGATVGVLLDLNKHTLTFFINGQQQGPTAFSHVDGVFMPALSLNRNVQVTLHTGLE 770

Query: 699 VP 700
           VP
Sbjct: 771 VP 772


>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
          Length = 728

 Score =  201 bits (512), Expect = 1e-51
 Identities = 158/619 (25%), Positives = 276/619 (44%), Gaps = 90/619 (14%)

Query: 1   MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY 60
           ++ +E EL CP C   +  P+ILPC H++C  C + +L+                     
Sbjct: 24  IKNIERELICPACKELFTHPLILPCQHSICHKCVKELLLTL------------------- 64

Query: 61  DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPAL--- 117
                         D  +   G   S  ++P  + P+      P+M        P     
Sbjct: 65  --------------DDSFNDVGSDNSNQSSPRLRLPS------PSMDKIDRINRPGWKRN 104

Query: 118 APVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSK--AAALKCQLCEKAP 175
           +  PR +   CP C   + L +RG+ G  +N  LE +++RY+Q+   A A+ C LC+  P
Sbjct: 105 SLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVERYRQAARAATAIMCDLCKPPP 164

Query: 176 KEATVMCEQCDVFYCDPCRLRCHPPRGPL-AKHRLVPPAQGRVSRRLSPRKVSTCTDHEL 234
           +E+T  C  C   YC+ C  + H P G + A+H  V P     +    P K+  C +HE 
Sbjct: 165 QESTKSCMDCSASYCNEC-FKIHHPWGTIKAQHEYVGP-----TTNFRP-KILMCPEHET 217

Query: 235 ENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEF 294
           E  +MYC  C+ PVC+ C   G H++H V  + + +K  K +LS+ ++ L  +  + K  
Sbjct: 218 ERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQ 277

Query: 295 LVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQIS 354
           + +L  ++++ + N    +   +   + L + L  RK+ +L  ++   + +L   + Q+ 
Sbjct: 278 ISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQME 337

Query: 355 HCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDF- 413
                L +  GL+ Y  EV+KE D S F+Q +  L  R+    +     +  P   T F 
Sbjct: 338 EYQ-GLLENNGLVGYAQEVLKETDQSCFVQTAKQLHLRIQKATE--SLKSFRPAAQTSFE 394

Query: 414 DLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPAD 473
           D  ++ S   + + +L F     SS +   P +  E+   +NN A ++W  P      AD
Sbjct: 395 DYVVNTSKQTELLGELSFF----SSGID-VPEINEEQSKVYNN-ALINWHHPEKD--KAD 446

Query: 474 GYILE---LDDGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVL 530
            Y+LE   ++  +   + E+ V   T   +  L  +STY  RV+A+  +  SP S+ L+L
Sbjct: 447 SYVLEYRKINRDDEMSWNEIEV-CGTSKIIQDLENSSTYAFRVRAYKGSICSPCSRELIL 505

Query: 531 QT--SEVAWFAFDPGSAHS-------------------DIILSNDNLTVTCSSYDDRVVL 569
            T  + V  F FD    ++                   +++L+ + + V   +  D  ++
Sbjct: 506 HTPPAPVFSFLFDEKCGYNNEHLLLNLKRDRVESRAGFNLLLAAERIQVGYYTSLD-YII 564

Query: 570 GKTGFSKGIHYWELTVDRY 588
           G TG +KG H+W   V+ Y
Sbjct: 565 GDTGITKGKHFWAFRVEPY 583


>gi|223890259 midline 2 isoform 2 [Homo sapiens]
          Length = 705

 Score =  197 bits (500), Expect = 4e-50
 Identities = 163/627 (25%), Positives = 260/627 (41%), Gaps = 75/627 (11%)

Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAA---------------------- 165
           CP C   + L+ RGL G  +N  L+ +IDR+Q++  +                       
Sbjct: 76  CPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSE 135

Query: 166 -LKCQLCEK-APKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSP 223
            + CQ CE+  P++A   C  C+V YCD C    HP + P   HRLV P      R +  
Sbjct: 136 RIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGI-- 193

Query: 224 RKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNG 283
               TC DHE E  +MYCV     +C  C   G+H  H+V +L   ++  K  L   L  
Sbjct: 194 ----TCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTN 249

Query: 284 LSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHE 343
           L  R  E +  + +L  + QQ++ N+   EA L+ +CD L++ + +RK  +  ++ +   
Sbjct: 250 LVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKV 309

Query: 344 HKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKG 403
            KL+ +  Q+++C   L ++T L+     ++KEND + FLQ +  +  RV +        
Sbjct: 310 MKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATA--SSQ 367

Query: 404 TLTPRMTTD---FDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460
            L P +  +    + +LD S   + +  LD++        P  P ++ E C   +++ T+
Sbjct: 368 VLIPDINFNDAFENFALDFSREKKLLEGLDYL------TAPNPPSIREELCTASHDTITV 421

Query: 461 SWKQPPLSTVPADGYILELDDGNG-GQFREVYVG----------KETMCTVDGLHFNSTY 509
            W      ++    Y L+     G   F  +Y            K+   TV GL   + Y
Sbjct: 422 HWISDDEFSI--SSYELQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRY 479

Query: 510 NARVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTV----------- 558
              VKA N+ G      T +   S+   F  DP   H  + +SND L +           
Sbjct: 480 IFIVKAINQAGSRNSEPTRLKTNSQP--FKLDPKMTHKKLKISNDGLQMEKDESSLKKSH 537

Query: 559 TCSSYDDRVVLGKTG---FSKGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKA 615
           T   +      G  G      G HYWE+ +     +   A G+A     K+  +GK+  +
Sbjct: 538 TPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWY---AIGIAYKSAPKNEWIGKNASS 594

Query: 616 WAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKNLTFFINDEQQGPIAFDNV 675
           W     N+     HNN           K   +GVLLD +   L+F+          FD  
Sbjct: 595 WVFSRCNSNFVVRHNNKEMLVDVPPHLK--RLGVLLDYDNNMLSFYDPANSLHLHTFDVT 652

Query: 676 EGLFFPAVSLNRNVQVTLHTGLPVPDF 702
             L         N  + + +GLP PDF
Sbjct: 653 FILPVCPTFTIWNKSLMILSGLPAPDF 679


>gi|148833499 midline 1 [Homo sapiens]
          Length = 667

 Score =  193 bits (490), Expect = 5e-49
 Identities = 166/624 (26%), Positives = 262/624 (41%), Gaps = 71/624 (11%)

Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSK-----------------------AA 164
           CP C   + L  RGL G  +N  L+ +IDR+Q++                        A 
Sbjct: 56  CPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAE 115

Query: 165 ALKCQLCEKAP-KEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSP 223
            + CQ C++ P ++A   C  C+V YCD C    HP + P   HRL+ P      R L  
Sbjct: 116 KVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM- 174

Query: 224 RKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNG 283
                C +HE E  +MYCV     +C  C   G+H  H+V AL   +   K  L   L  
Sbjct: 175 -----CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTN 229

Query: 284 LSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHE 343
           L  R  E +  L +L    Q ++ N+   EA L  +CD LI+ + +R+  +  ++ +   
Sbjct: 230 LIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKV 289

Query: 344 HKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKG 403
            +L+ +  QI++C   + ++  L+      +KEND + FLQ +  +  RV +        
Sbjct: 290 MRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATA--SSQ 347

Query: 404 TLTPRMTTD--FD-LSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460
            L P +  +  FD  +LD S   + +  LD++        P  P ++ E C    ++ T+
Sbjct: 348 VLIPEINLNDTFDTFALDFSREKKLLECLDYL------TAPNPPTIREELCTASYDTITV 401

Query: 461 SWKQPPLSTVPADGYILELDDG---------NGGQFREVYVGKETMCTVDGLHFNSTYNA 511
            W      +V +      +  G         +   +  V   K+   TV GL   + Y  
Sbjct: 402 HWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIF 461

Query: 512 RVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTV------------- 558
            VKA N+ G S  S+   L+T+    F  DP SAH  + +S+DNLTV             
Sbjct: 462 MVKAINQAG-SRSSEPGKLKTNSQP-FKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTP 519

Query: 559 -TCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWA 617
              +S     V G      G HYWE+ +     +   A G+A     K   +GK+  +WA
Sbjct: 520 ERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWY---AIGLAYKSAPKHEWIGKNSASWA 576

Query: 618 MYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKNLTFFINDEQQGPIAFDNVEG 677
           +   NN +W + +NS     E        +G+LLD +  ++ F+          FD    
Sbjct: 577 LCRCNN-NWVVRHNSKEIPIEPA-PHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFA 634

Query: 678 LFFPAVSLNRNVQVTLHTGLPVPD 701
                     N  +T+ TGLP+PD
Sbjct: 635 QPVCPTFTVWNKCLTIITGLPIPD 658


>gi|4557753 midline 1 [Homo sapiens]
          Length = 667

 Score =  193 bits (490), Expect = 5e-49
 Identities = 166/624 (26%), Positives = 262/624 (41%), Gaps = 71/624 (11%)

Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSK-----------------------AA 164
           CP C   + L  RGL G  +N  L+ +IDR+Q++                        A 
Sbjct: 56  CPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAE 115

Query: 165 ALKCQLCEKAP-KEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSP 223
            + CQ C++ P ++A   C  C+V YCD C    HP + P   HRL+ P      R L  
Sbjct: 116 KVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM- 174

Query: 224 RKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNG 283
                C +HE E  +MYCV     +C  C   G+H  H+V AL   +   K  L   L  
Sbjct: 175 -----CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTN 229

Query: 284 LSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHE 343
           L  R  E +  L +L    Q ++ N+   EA L  +CD LI+ + +R+  +  ++ +   
Sbjct: 230 LIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKV 289

Query: 344 HKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKG 403
            +L+ +  QI++C   + ++  L+      +KEND + FLQ +  +  RV +        
Sbjct: 290 MRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATA--SSQ 347

Query: 404 TLTPRMTTD--FD-LSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460
            L P +  +  FD  +LD S   + +  LD++        P  P ++ E C    ++ T+
Sbjct: 348 VLIPEINLNDTFDTFALDFSREKKLLECLDYL------TAPNPPTIREELCTASYDTITV 401

Query: 461 SWKQPPLSTVPADGYILELDDG---------NGGQFREVYVGKETMCTVDGLHFNSTYNA 511
            W      +V +      +  G         +   +  V   K+   TV GL   + Y  
Sbjct: 402 HWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIF 461

Query: 512 RVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTV------------- 558
            VKA N+ G S  S+   L+T+    F  DP SAH  + +S+DNLTV             
Sbjct: 462 MVKAINQAG-SRSSEPGKLKTNSQP-FKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTP 519

Query: 559 -TCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWA 617
              +S     V G      G HYWE+ +     +   A G+A     K   +GK+  +WA
Sbjct: 520 ERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWY---AIGLAYKSAPKHEWIGKNSASWA 576

Query: 618 MYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKNLTFFINDEQQGPIAFDNVEG 677
           +   NN +W + +NS     E        +G+LLD +  ++ F+          FD    
Sbjct: 577 LCRCNN-NWVVRHNSKEIPIEPA-PHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFA 634

Query: 678 LFFPAVSLNRNVQVTLHTGLPVPD 701
                     N  +T+ TGLP+PD
Sbjct: 635 QPVCPTFTVWNKCLTIITGLPIPD 658


>gi|15451852 midline 1 [Homo sapiens]
          Length = 667

 Score =  193 bits (490), Expect = 5e-49
 Identities = 166/624 (26%), Positives = 262/624 (41%), Gaps = 71/624 (11%)

Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSK-----------------------AA 164
           CP C   + L  RGL G  +N  L+ +IDR+Q++                        A 
Sbjct: 56  CPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAE 115

Query: 165 ALKCQLCEKAP-KEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSP 223
            + CQ C++ P ++A   C  C+V YCD C    HP + P   HRL+ P      R L  
Sbjct: 116 KVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLM- 174

Query: 224 RKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNG 283
                C +HE E  +MYCV     +C  C   G+H  H+V AL   +   K  L   L  
Sbjct: 175 -----CLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTN 229

Query: 284 LSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHE 343
           L  R  E +  L +L    Q ++ N+   EA L  +CD LI+ + +R+  +  ++ +   
Sbjct: 230 LIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKV 289

Query: 344 HKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKG 403
            +L+ +  QI++C   + ++  L+      +KEND + FLQ +  +  RV +        
Sbjct: 290 MRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATA--SSQ 347

Query: 404 TLTPRMTTD--FD-LSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460
            L P +  +  FD  +LD S   + +  LD++        P  P ++ E C    ++ T+
Sbjct: 348 VLIPEINLNDTFDTFALDFSREKKLLECLDYL------TAPNPPTIREELCTASYDTITV 401

Query: 461 SWKQPPLSTVPADGYILELDDG---------NGGQFREVYVGKETMCTVDGLHFNSTYNA 511
            W      +V +      +  G         +   +  V   K+   TV GL   + Y  
Sbjct: 402 HWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIF 461

Query: 512 RVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTV------------- 558
            VKA N+ G S  S+   L+T+    F  DP SAH  + +S+DNLTV             
Sbjct: 462 MVKAINQAG-SRSSEPGKLKTNSQP-FKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTP 519

Query: 559 -TCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWA 617
              +S     V G      G HYWE+ +     +   A G+A     K   +GK+  +WA
Sbjct: 520 ERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWY---AIGLAYKSAPKHEWIGKNSASWA 576

Query: 618 MYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKNLTFFINDEQQGPIAFDNVEG 677
           +   NN +W + +NS     E        +G+LLD +  ++ F+          FD    
Sbjct: 577 LCRCNN-NWVVRHNSKEIPIEPA-PHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFA 634

Query: 678 LFFPAVSLNRNVQVTLHTGLPVPD 701
                     N  +T+ TGLP+PD
Sbjct: 635 QPVCPTFTVWNKCLTIITGLPIPD 658


>gi|223890257 midline 2 isoform 1 [Homo sapiens]
          Length = 735

 Score =  186 bits (473), Expect = 5e-47
 Identities = 164/657 (24%), Positives = 262/657 (39%), Gaps = 105/657 (15%)

Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAA---------------------- 165
           CP C   + L+ RGL G  +N  L+ +IDR+Q++  +                       
Sbjct: 76  CPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSE 135

Query: 166 -LKCQLCEK-APKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSP 223
            + CQ CE+  P++A   C  C+V YCD C    HP + P   HRLV P      R +  
Sbjct: 136 RIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGI-- 193

Query: 224 RKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNG 283
               TC DHE E  +MYCV     +C  C   G+H  H+V +L   ++  K  L   L  
Sbjct: 194 ----TCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTN 249

Query: 284 LSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHE 343
           L  R  E +  + +L  + QQ++ N+   EA L+ +CD L++ + +RK  +  ++ +   
Sbjct: 250 LVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKV 309

Query: 344 HKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKG 403
            KL+ +  Q+++C   L ++T L+     ++KEND + FLQ +  +  RV +        
Sbjct: 310 MKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATA--SSQ 367

Query: 404 TLTPRMTTD---FDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460
            L P +  +    + +LD S   + +  LD++        P  P ++ E C   +++ T+
Sbjct: 368 VLIPDINFNDAFENFALDFSREKKLLEGLDYL------TAPNPPSIREELCTASHDTITV 421

Query: 461 SWKQPPLSTVPADGYILELDDGNG------------GQFREVYVGKETMC---------- 498
            W      ++    Y L+     G            G + E+   KE +           
Sbjct: 422 HWISDDEFSI--SSYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPRG 479

Query: 499 -------------------TVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFA 539
                              TV GL   + Y   VKA N+ G      T +   S+   F 
Sbjct: 480 LYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQP--FK 537

Query: 540 FDPGSAHSDIILSNDNLTV-----------TCSSYDDRVVLGKTG---FSKGIHYWELTV 585
            DP   H  + +SND L +           T   +      G  G      G HYWE+ +
Sbjct: 538 LDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVM 597

Query: 586 DRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGA 645
                +   A G+A     K+  +GK+  +W     N+     HNN           K  
Sbjct: 598 GSSTWY---AIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLK-- 652

Query: 646 TIGVLLDLNRKNLTFFINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLPVPDF 702
            +GVLLD +   L+F+          FD    L         N  + + +GLP PDF
Sbjct: 653 RLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDF 709


>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
          Length = 759

 Score =  177 bits (449), Expect = 3e-44
 Identities = 171/634 (26%), Positives = 264/634 (41%), Gaps = 106/634 (16%)

Query: 1   MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQ--------TPESE------- 45
           M+ ME+EL CPVC   Y++P++LPC+HN+CQACAR +L Q         P SE       
Sbjct: 24  MKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPAST 83

Query: 46  -SPQSHRAAGSGVSDYDYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPP 104
            S +S R +   +   D LD           SG+G+Y G       P       V +FP 
Sbjct: 84  PSTRSPRLSRRTLPKPDRLD-------RLLKSGFGTYPGRKRGALHP------QVIMFP- 129

Query: 105 AMPPPATHLSPALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKA- 163
                                  CP C   + L +RGL G  +N  LE V++RY+QS + 
Sbjct: 130 -----------------------CPACQGDVELGERGLAGLFRNLTLERVVERYRQSVSV 166

Query: 164 -AALKCQLCEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLS 222
             A+ CQLC+  P EAT  C +C   +C+ C    HP     A+H    P        LS
Sbjct: 167 GGAILCQLCKPPPLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPT-------LS 219

Query: 223 PR-KVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQAL 281
            R K   C DH+ E  + YC  C+  VC  C     HS H++  + + ++  K +L+++L
Sbjct: 220 FRPKGLMCPDHK-EEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSL 278

Query: 282 NGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKE 341
             +       +  + +L   V+  + +  + +  +      L   L  ++A LL  + + 
Sbjct: 279 TYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEEC 338

Query: 342 HEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWG 401
            + +L  +  QI      L   +GL+ Y  EV+KE D   F+Q +  L  R+    +   
Sbjct: 339 QQERLARLSAQIQEHR-SLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATE--A 395

Query: 402 KGTLTPRMTTDF-DLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460
             T  P  ++ F    LD    ++ + +L+F++      VP  P++  +    + +   L
Sbjct: 396 LQTFRPAASSSFRHCQLDVGREMKLLTELNFLR------VPEAPVIDTQRTFAY-DQIFL 448

Query: 461 SWKQPPLSTVPADGYILEL--------DDGNGGQFREVYVGKETMCTVDGLHFNSTYNAR 512
            W+ PP S  PA  Y +E               Q RE   G  T   ++     S Y  R
Sbjct: 449 CWRLPPHSP-PAWHYTVEFRRTDVPAQPGPTRWQRREEVRG--TSALLENPDTGSVYVLR 505

Query: 513 VKAFNKTGVSPYSKTLVLQT--SEVAWFAFDP--GSAHSDIILSNDNLTV---------- 558
           V+  NK G   YS+ + L T  + V  F  D   G++   + +S D   V          
Sbjct: 506 VRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDSRWGASRERLAISKDQRAVRSVPGLPLLL 565

Query: 559 ------TCSSYDDRVVLGKTGFSKGIHYWELTVD 586
                 T       VVLG    ++G  YW   VD
Sbjct: 566 AADRLLTGCHLSVDVVLGDVAVTQGRSYWACAVD 599


>gi|89886468 fibronectin type III and SPRY domain containing 1-like
           isoform 1 [Homo sapiens]
          Length = 498

 Score =  103 bits (258), Expect = 4e-22
 Identities = 111/455 (24%), Positives = 188/455 (41%), Gaps = 81/455 (17%)

Query: 274 KSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQ 333
           K  L + ++ L+++  E + F+  L + ++ +QENS    + L  + D+L   L+  K  
Sbjct: 5   KEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 64

Query: 334 LLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393
           ++  + +E   K + ++ QIS C   L  +  L+E+    +   +P  F + +  +  RV
Sbjct: 65  MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 124

Query: 394 HLTEDQWGKGTLTPRMTTDF-DLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECC 452
             T     + +L P+++ +   L +D S   Q +  L F+      PVP  P +   EC 
Sbjct: 125 --TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFL------PVPKAPEIDPVECL 176

Query: 453 THNNSATLSWKQPPLSTVPADGYILELDDGNGGQFREVYVG---------KETMCTVDGL 503
             +NS T++W+ P       D +ILE    N      V            K T  T+ GL
Sbjct: 177 VADNSVTVAWRMPEEDN-KIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGL 235

Query: 504 HFNSTY-NARVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTVTCSS 562
            F+S Y N RV+A NK     YS  + L+T  +  F  D  S+H ++ + +     TC  
Sbjct: 236 KFDSKYMNFRVRACNKAVAGEYSDPVTLETKALN-FNLDNSSSHLNLKVED-----TCVE 289

Query: 563 YD-----------------------------------------DR------VVLGKTGFS 575
           +D                                         DR       VLG T   
Sbjct: 290 WDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIE 349

Query: 576 KGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHN--NSH 633
            G HYWE+   +  +    + GVA   + K   LGK + +W ++V+N   W  +     H
Sbjct: 350 SGQHYWEVKAQK--DCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNN---WLQNTFAAKH 404

Query: 634 TNRTEG-GITKGATIGVLLDLNRKNLTFFINDEQQ 667
            N+ +   +T    IGV  D +   L+F+  + +Q
Sbjct: 405 NNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQ 439


>gi|223718222 fibronectin type III and SPRY domain containing 1-like
           isoform 3 [Homo sapiens]
          Length = 530

 Score =  103 bits (258), Expect = 4e-22
 Identities = 111/457 (24%), Positives = 189/457 (41%), Gaps = 81/457 (17%)

Query: 272 LHKSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRK 331
           L +  L + ++ L+++  E + F+  L + ++ +QENS    + L  + D+L   L+  K
Sbjct: 35  LQQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVK 94

Query: 332 AQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIR 391
             ++  + +E   K + ++ QIS C   L  +  L+E+    +   +P  F + +  +  
Sbjct: 95  ESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKD 154

Query: 392 RVHLTEDQWGKGTLTPRMTTDF-DLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEE 450
           RV  T     + +L P+++ +   L +D S   Q +  L F+      PVP  P +   E
Sbjct: 155 RV--TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFL------PVPKAPEIDPVE 206

Query: 451 CCTHNNSATLSWKQPPLSTVPADGYILELDDGNGGQFREVYVG---------KETMCTVD 501
           C   +NS T++W+ P       D +ILE    N      V            K T  T+ 
Sbjct: 207 CLVADNSVTVAWRMPEEDN-KIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLS 265

Query: 502 GLHFNSTY-NARVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTVTC 560
           GL F+S Y N RV+A NK     YS  + L+T  +  F  D  S+H ++ + +     TC
Sbjct: 266 GLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKALN-FNLDNSSSHLNLKVED-----TC 319

Query: 561 SSYD-----------------------------------------DR------VVLGKTG 573
             +D                                         DR       VLG T 
Sbjct: 320 VEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTA 379

Query: 574 FSKGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHN--N 631
              G HYWE+   +  +    + GVA   + K   LGK + +W ++V+N   W  +    
Sbjct: 380 IESGQHYWEVKAQK--DCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNN---WLQNTFAA 434

Query: 632 SHTNRTEG-GITKGATIGVLLDLNRKNLTFFINDEQQ 667
            H N+ +   +T    IGV  D +   L+F+  + +Q
Sbjct: 435 KHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQ 471


>gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]
          Length = 358

 Score = 90.9 bits (224), Expect = 4e-18
 Identities = 64/266 (24%), Positives = 110/266 (41%), Gaps = 53/266 (19%)

Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATVMCEQCDV 187
           CP C   ++LD  G+ G  +N ++E +ID Y+Q  +                        
Sbjct: 78  CPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSR----------------------- 114

Query: 188 FYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYCVQCKMP 247
                                   P   +  + L       C +HE E  ++YC+ C++P
Sbjct: 115 ------------------------PLHSKAEQHLM------CEEHEEEKINIYCLSCEVP 144

Query: 248 VCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQE 307
            C  C   G H   EV  L  ++K  KS+LS  +  L       +  + Q+  + Q I++
Sbjct: 145 TCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAMLVAGNDRVQAVITQMEEVCQTIED 204

Query: 308 NSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLM 367
           NS   +  L  + ++L   L  RK +LL  + +E E KL+ VR  I      L  ++ L+
Sbjct: 205 NSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLEASSKLV 264

Query: 368 EYCLEVIKENDPSGFLQISDALIRRV 393
           E  ++ ++E   + +LQ +  LI +V
Sbjct: 265 ESAIQSMEEPQMALYLQQAKELINKV 290



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 17/38 (44%), Positives = 28/38 (73%), Gaps = 1/38 (2%)

Query: 1  MEEMEEELKCPVCGSFYREPI-ILPCSHNLCQACARNI 37
          M+ +E++L CP+C   + +P+ ILPC HNLC+ CA ++
Sbjct: 17 MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDV 54


>gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]
          Length = 353

 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 61/266 (22%), Positives = 113/266 (42%), Gaps = 54/266 (20%)

Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATVMCEQCDV 187
           CP C   +I+D  G+ G  +N ++E +ID Y+                       ++C  
Sbjct: 75  CPTCRHEVIMDRHGVYGLQRNLLVENIIDIYK-----------------------QECS- 110

Query: 188 FYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYCVQCKMP 247
                                         SR L       C +HE E  ++YC+ C++P
Sbjct: 111 ------------------------------SRPLQKGSHPMCKEHEDEKINIYCLTCEVP 140

Query: 248 VCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQE 307
            C  C   G H + EV  L ++++  K++L+  ++ L       +  + QL +  +  +E
Sbjct: 141 TCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISMLVAGNDRVQTIITQLEDSRRVTKE 200

Query: 308 NSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLM 367
           NS + +  L  + D L   L+ +K++LL R+ +E E KL  +   I     +L ++T L+
Sbjct: 201 NSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQEKKLSFIEALIQQYQEQLDKSTKLV 260

Query: 368 EYCLEVIKENDPSGFLQISDALIRRV 393
           E  ++ + E   + FL  +  LI+ +
Sbjct: 261 ETAIQSLDEPGGATFLLTAKQLIKSI 286



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 19/38 (50%), Positives = 28/38 (73%), Gaps = 1/38 (2%)

Query: 1  MEEMEEELKCPVCGSFYREPI-ILPCSHNLCQACARNI 37
          ME +E++L CP+C   + +P+ ILPC HNLC+ CA +I
Sbjct: 14 MENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDI 51


>gi|13236585 fibronectin type III and SPRY domain containing 1 [Homo
           sapiens]
          Length = 496

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 97/412 (23%), Positives = 168/412 (40%), Gaps = 82/412 (19%)

Query: 274 KSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQ 333
           +  L + +  L+ + +E + F+  L+ M+  ++ NS + +  L A+  +L   L   K  
Sbjct: 5   REALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEELKEG 64

Query: 334 LLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393
           +L ++ ++   +   +++Q++ CT  L  +  L+E   + ++  D   F Q +  +   V
Sbjct: 65  MLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIKDGV 124

Query: 394 HLTEDQWGKGTLTP--RMTTDFDLSLDNSPLLQSIHQ-LDFVQVKASSPVPATPILQLEE 450
                     T+ P  R++    +S + S L+    Q    +Q     PVP+ P++ L E
Sbjct: 125 ----------TMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAE 174

Query: 451 CCTHNNSATLSWKQPPLSTVPADGYILELDDGN--------GGQFREVYVG-KETMCTVD 501
               +N  TL W+ P   +   D Y+LE    N          Q   V  G ++T  T+ 
Sbjct: 175 SLVADNCVTLVWRMPDEDS-KIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLT 233

Query: 502 GLHFNSTY-NARVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTVTC 560
           GL F+  Y N RVKA NK     +S+ + L+T     F  D  ++H +  L  D+L+V  
Sbjct: 234 GLKFDMKYMNFRVKACNKAVAGEFSEPVTLET-PAFMFRLDASTSHQN--LRVDDLSVEW 290

Query: 561 SSYDDRV-----------------------------------------------VLGKTG 573
            +   +V                                               VLG T 
Sbjct: 291 DAMGGKVQDIKAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAESYTVLGDTL 350

Query: 574 FSKGIHYWELTVDRYDNHPDP---AFGVARMDVMKDVMLGKDDKAWAMYVDN 622
              G HYWE+   RY+  PD      GVA   + +   LGK   +W ++V+N
Sbjct: 351 IDGGEHYWEV---RYE--PDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNN 397


>gi|124487387 ring finger protein 207 [Homo sapiens]
          Length = 634

 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 73/273 (26%), Positives = 123/273 (45%), Gaps = 15/273 (5%)

Query: 126 ITCPQCHRSLILDDRGLRGFPK-NRVLEGVIDRYQQSKAAA--LKCQL-CEKAPKEATVM 181
           +TCP C    +L  +G  G P  +R+L+ ++D       A     C L C +   E T  
Sbjct: 58  LTCPLCQHQTVL--KGPSGLPPVDRLLQFLVDSSGDGVEAVRCANCDLECSEQDVETTYF 115

Query: 182 CEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYC 241
           C  C    C  CR   H  R   A+H +V  A G+ SR + P+K   CT H  E + ++ 
Sbjct: 116 CNTCGQPLCARCRDETHRAR-MFARHDIV--ALGQRSRDV-PQK---CTLHA-EPYLLFS 167

Query: 242 VQCKMPVCYQCLEE-GKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN 300
              K+ +C +C  +  K S      L + +     +L QA+  +       +E +  L+ 
Sbjct: 168 TDKKLLLCIRCFRDMQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQA 227

Query: 301 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL 360
           MV++++ ++ E E  + A   ++ D L  RKA LL  V  ++E K K  ++Q+SH    L
Sbjct: 228 MVEEVRHSAAEEEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLL 287

Query: 361 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393
                 +  C   +   + + FL +   L+ R+
Sbjct: 288 PTLQVHLVICSSFLSLANKAEFLDLGYELMERL 320



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 12/28 (42%), Positives = 15/28 (53%)

Query: 8  LKCPVCGSFYREPIILPCSHNLCQACAR 35
          L CP+C   Y  P +L C H+ C  C R
Sbjct: 23 LVCPLCHVQYERPCLLDCFHDFCAGCLR 50


>gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]
          Length = 400

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 64/272 (23%), Positives = 115/272 (42%), Gaps = 23/272 (8%)

Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQ-----LCEKAPKE-ATVM 181
           CP C   ++LD  G+ G  +N ++E +ID Y+Q  +  L  +     +CE+  +E   + 
Sbjct: 78  CPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHLMCEEHEEEKINIY 137

Query: 182 CEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYC 241
           C  C+V  C  C++        +A    +   Q +    L PR                 
Sbjct: 138 CLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTLLPR----------------- 180

Query: 242 VQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRNM 301
           ++C       C  +   SS          K+  S+LS  +  L       +  + Q+  +
Sbjct: 181 LECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQMEEV 240

Query: 302 VQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLR 361
            Q I++NS   +  L  + ++L   L  RK +LL  + +E E KL+ VR  I      L 
Sbjct: 241 CQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLE 300

Query: 362 QTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393
            ++ L+E  ++ ++E   + +LQ +  LI +V
Sbjct: 301 ASSKLVESAIQSMEEPQMALYLQQAKELINKV 332



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 17/38 (44%), Positives = 28/38 (73%), Gaps = 1/38 (2%)

Query: 1  MEEMEEELKCPVCGSFYREPI-ILPCSHNLCQACARNI 37
          M+ +E++L CP+C   + +P+ ILPC HNLC+ CA ++
Sbjct: 17 MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDV 54


>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
          Length = 4069

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 75/275 (27%), Positives = 123/275 (44%), Gaps = 28/275 (10%)

Query: 441  PATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILEL--DDGNGGQFREVYVGKETMC 498
            P+TP+++ E+C    N+AT+ W+  P +    + Y LE        G+    + G + + 
Sbjct: 3804 PSTPVIRAEDCTVCWNTATIRWR--PTTPEATETYTLEYCRQHSPEGEGLRSFSGIKGLQ 3861

Query: 499  TVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTV 558
                L  N  Y   V+A N  G S  S+  ++ T     F     +AH  + +S+     
Sbjct: 3862 LKVNLQPNDNYFFYVRAINAFGTSEQSEAALISTRGTR-FLLLRETAHPALHISSSG--- 3917

Query: 559  TCSSYDDR-------VVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGK 611
            T  S+ +R        VLG+   S G HYWE TV    + P    G+     ++   LG+
Sbjct: 3918 TVISFGERRRLTEIPSVLGEELPSCGQHYWETTV---TDCPAYRLGICSSSAVQAGALGQ 3974

Query: 612  DDKAWAMYV-DNNRSWFMHNN--SHTNRTEGGITKGATIGVLLDLNRKNLTFFINDEQQ- 667
             + +W M+  +  R  F ++   S  + TE    + A +G+LLD N + L F   + +Q 
Sbjct: 3975 GETSWYMHCSEPQRYTFFYSGIVSDVHVTE----RPARVGILLDYNNQRLIFINAESEQL 4030

Query: 668  -GPIAFDNVEGLFFPAVSLNRNVQVTLHTGLPVPD 701
               I     EG+  PA +L +  + TLH G+  PD
Sbjct: 4031 LFIIRHRFNEGV-HPAFALEKPGKCTLHLGIEPPD 4064



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 77/329 (23%), Positives = 130/329 (39%), Gaps = 30/329 (9%)

Query: 220  RLSPRKVSTCTDHELENHSM--YCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQL 277
            +LS   V+     EL+   +  YC  CK P+       G H  HEV  L       K QL
Sbjct: 3490 QLSSEVVTEKAQKELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQL 3549

Query: 278  SQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALID---ALNRRKAQL 334
            ++ L  L +++   + F+ ++ +    I+EN  + E  L  Q + ++    A    KAQ 
Sbjct: 3550 AEFLENLQEKSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQS 3609

Query: 335  LARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVH 394
               V K+   K++ + +Q+ H    +      +E  +   +E D + FL   + +  R+ 
Sbjct: 3610 FEEVKKK---KMEFLHEQMVHFLQSMDTAKDTLETIVREAEELDEAVFLTSFEEINERLL 3666

Query: 395  LTEDQWGKGTLTPRMTTDFDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTH 454
               +        P   + F+   D+S            Q+     VP  P L+ +E    
Sbjct: 3667 SAMESTASLEKMPAAFSLFEHYDDSSARSD--------QMLKQVAVPQPPRLEPQE---- 3714

Query: 455  NNSAT-----LSWKQPPLSTVPA-DGYILE--LDDGNGGQFREVY--VGKETMCTVDGLH 504
             NSAT     + W       + +   Y +E   DD    +  E Y    KE+ C  + L 
Sbjct: 3715 PNSATSTTIAVYWSMNKEDVIDSFQVYCMEEPQDDQEVNELVEEYRLTVKESYCIFEDLE 3774

Query: 505  FNSTYNARVKAFNKTGVSPYSKTLVLQTS 533
             +  Y   V A N TG S  S+  + +T+
Sbjct: 3775 PDRCYQVWVMAVNFTGCSLPSERAIFRTA 3803


>gi|55741632 fibronectin type III and SPRY domain containing 2 [Homo
           sapiens]
          Length = 749

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 78/286 (27%), Positives = 117/286 (40%), Gaps = 37/286 (12%)

Query: 441 PATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELDDGNGGQ---FREVYVGKETM 497
           P+ PI++ +E  +   +  + W+   L+  P D Y +EL      +     E  VG  T 
Sbjct: 469 PSPPIIKTKEIRSCEEAVLICWESGNLN--PVDSYTVELTQAESPEASGVTESVVGIPTC 526

Query: 498 CTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLT 557
            +V  L    +Y   V+A N  G S  S+   + T   ++F  +  + H  + +S D LT
Sbjct: 527 ESVVQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIG-SYFRLNKDTCHPWLTISEDGLT 585

Query: 558 VTCS---------SYDDR------VVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVARMD 602
              S         S  D        V+G     +G HYWE+ VD    H D   GVA  D
Sbjct: 586 AVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVEVDE---HLDYRVGVAFAD 642

Query: 603 VMKDVMLGKDDKAWAM---YVDNNRSW-FMHNNSHTNRTEGGI---TKGATIGVLLDLNR 655
           V K   LG +  +W M   +  +   + F+H     NRT   I        IG+LLD   
Sbjct: 643 VRKQEDLGANCLSWCMRHTFASSRHKYEFLH-----NRTTPDIRITVPPKKIGILLDYEH 697

Query: 656 KNLTFFINDEQQGPIAFD-NVEGLFFPAVSLNRNVQVTLHTGLPVP 700
             L+FF  D  Q    F   +     P  SL +   + +H G+ +P
Sbjct: 698 SKLSFFNVDLSQHLYTFSCQLHEFVHPCFSLEKPGCLKVHNGISMP 743



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 75/313 (23%), Positives = 133/313 (42%), Gaps = 24/313 (7%)

Query: 231 DHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKE 290
           + E E   ++CV CK P+        +H  HEV  L    +  K ++ + +  L  +  E
Sbjct: 170 EDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE 229

Query: 291 AKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVR 350
            + F   L  +   ++EN  + E    +  + +++ L ++  + +  + ++ + KL+ + 
Sbjct: 230 MENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALY 289

Query: 351 DQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMT 410
            Q+  C   L     LME   E+  E +   F++ + A+        D+ GK   T    
Sbjct: 290 GQLVSCGENLDTCKELMETIEEMCHE-EKVDFIKDAVAMA-------DRLGKFLKTK--- 338

Query: 411 TDFDLSLDNSPLLQSIHQLDFVQVKASS---PVPATPIL--QLEECCTHNNSATLSWKQP 465
           TD ++S       Q++   D  Q+  S    P P+ P++  Q+    T  +S  + W   
Sbjct: 339 TDVEISAQPEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSAT-GSSVRVCWSLY 397

Query: 466 PLSTVPADGYILE---LDDGNGG--QFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTG 520
              TV  + Y L    + D + G  Q       KET C+V  L  N+ Y   V A N+ G
Sbjct: 398 SDDTV--ESYQLSYRPVQDSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAG 455

Query: 521 VSPYSKTLVLQTS 533
            SP S+  V  T+
Sbjct: 456 PSPSSERAVYMTA 468


>gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]
          Length = 452

 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 43/165 (26%), Positives = 81/165 (49%)

Query: 229 CTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRA 288
           C +HE E  ++YC+ C++P C  C   G H   +V  L  +++  KS+LS  +  L    
Sbjct: 124 CEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSN 183

Query: 289 KEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKV 348
              +  + QL +  + I+E   + +  L  + D L   L  RK ++   + +  E KL+ 
Sbjct: 184 DRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEH 243

Query: 349 VRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393
           VR  I   +  L   + L+E  ++ + E + + FLQ +  L++++
Sbjct: 244 VRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKI 288



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 18/38 (47%), Positives = 28/38 (73%), Gaps = 1/38 (2%)

Query: 1  MEEMEEELKCPVCGSFYREPI-ILPCSHNLCQACARNI 37
          M+ +E++L CP+C   + +P+ ILPC HNLC+ CA +I
Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDI 54



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 4/72 (5%)

Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQ---LCEKAPKE-ATVMCE 183
           CP C   ++LD  G+ G  +N ++E +ID Y+Q      K     +CE+  +E   + C 
Sbjct: 78  CPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEEERINIYCL 137

Query: 184 QCDVFYCDPCRL 195
            C+V  C  C++
Sbjct: 138 NCEVPTCSLCKV 149


>gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]
          Length = 548

 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 43/165 (26%), Positives = 81/165 (49%)

Query: 229 CTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRA 288
           C +HE E  ++YC+ C++P C  C   G H   +V  L  +++  KS+LS  +  L    
Sbjct: 124 CEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSN 183

Query: 289 KEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKV 348
              +  + QL +  + I+E   + +  L  + D L   L  RK ++   + +  E KL+ 
Sbjct: 184 DRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEH 243

Query: 349 VRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393
           VR  I   +  L   + L+E  ++ + E + + FLQ +  L++++
Sbjct: 244 VRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKI 288



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 18/38 (47%), Positives = 28/38 (73%), Gaps = 1/38 (2%)

Query: 1  MEEMEEELKCPVCGSFYREPI-ILPCSHNLCQACARNI 37
          M+ +E++L CP+C   + +P+ ILPC HNLC+ CA +I
Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDI 54



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 4/72 (5%)

Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQ---LCEKAPKE-ATVMCE 183
           CP C   ++LD  G+ G  +N ++E +ID Y+Q      K     +CE+  +E   + C 
Sbjct: 78  CPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEEERINIYCL 137

Query: 184 QCDVFYCDPCRL 195
            C+V  C  C++
Sbjct: 138 NCEVPTCSLCKV 149


>gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]
          Length = 540

 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 43/165 (26%), Positives = 81/165 (49%)

Query: 229 CTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRA 288
           C +HE E  ++YC+ C++P C  C   G H   +V  L  +++  KS+LS  +  L    
Sbjct: 124 CEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSN 183

Query: 289 KEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKV 348
              +  + QL +  + I+E   + +  L  + D L   L  RK ++   + +  E KL+ 
Sbjct: 184 DRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEH 243

Query: 349 VRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393
           VR  I   +  L   + L+E  ++ + E + + FLQ +  L++++
Sbjct: 244 VRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKI 288



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 18/38 (47%), Positives = 28/38 (73%), Gaps = 1/38 (2%)

Query: 1  MEEMEEELKCPVCGSFYREPI-ILPCSHNLCQACARNI 37
          M+ +E++L CP+C   + +P+ ILPC HNLC+ CA +I
Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDI 54



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 4/72 (5%)

Query: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQ---LCEKAPKE-ATVMCE 183
           CP C   ++LD  G+ G  +N ++E +ID Y+Q      K     +CE+  +E   + C 
Sbjct: 78  CPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRPEKKSDQPMCEEHEEERINIYCL 137

Query: 184 QCDVFYCDPCRL 195
            C+V  C  C++
Sbjct: 138 NCEVPTCSLCKV 149


>gi|54792146 tripartite motif-containing 47 [Homo sapiens]
          Length = 638

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 108/424 (25%), Positives = 151/424 (35%), Gaps = 102/424 (24%)

Query: 10  CPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDYDYLDLDKMS 69
           CP+C    REP+ LPC HN C AC   +            HR A                
Sbjct: 9   CPICLEPLREPVTLPCGHNFCLACLGALW----------PHRGA---------------- 42

Query: 70  LYSEADSGYGSYGGFASAPTTPCQKS-PNGVRVF----------------PPAMPPPATH 112
                 SG G  GG A  P   CQ+  P+G+++                 P + P PA  
Sbjct: 43  ------SGAGGPGGAARCPL--CQEPFPDGLQLRKNHTLSELLQLRQGSGPGSGPGPAPA 94

Query: 113 LSP------ALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAAL 166
           L+P      AL  VP  S    P+              +P                   +
Sbjct: 95  LAPEPSAPSALPSVPEPSAPCAPE-------------PWPAGE--------------EPV 127

Query: 167 KCQLC-EKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRK 225
           +C  C E A   A + C  C   +C P  L  H     L  HRLVPP + R+   L PR 
Sbjct: 128 RCDACPEGAALPAALSCLSCLASFC-PAHLGPHERSPALRGHRLVPPLR-RLEESLCPR- 184

Query: 226 VSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLS 285
                   L     YC   ++ +C  C  + +H  HE+  L     L +++ S+ L+ + 
Sbjct: 185 -------HLRPLERYCRAERVCLCEACAAQ-EHRGHELVPLEQERALQEAEQSKVLSAVE 236

Query: 286 DRAKEAKEFLVQLRNMVQQIQENSV-EFEACLVAQCDALIDALNRRKAQLLARVNKEHEH 344
           DR  E    + Q R  V  I+  +V E E       DA   AL   + Q+L  + +    
Sbjct: 237 DRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAA-ALQGFQTQVLGFIEEGEAA 295

Query: 345 KLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGT 404
            L   +  +     + R         L  + E D   FLQ  + L  R+ L ED  G G 
Sbjct: 296 MLGRSQGDLRR-QEEQRSRLSRARQNLSQVPEADSVSFLQ--ELLALRLAL-EDGCGPGP 351

Query: 405 LTPR 408
             PR
Sbjct: 352 GPPR 355


>gi|52487176 tripartite motif-containing 37 protein [Homo sapiens]
          Length = 964

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 60/236 (25%), Positives = 109/236 (46%), Gaps = 36/236 (15%)

Query: 160 QSKAAALKCQLCEKAPKEATVMCEQCDVFYCDPC--------RLRCHPPRGPLAKHRLVP 211
           +S A   +C +C +  ++A  +C  C    C  C        R +C   R PL    LV 
Sbjct: 7   ESIAEVFRCFICMEKLRDAR-LCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVN 65

Query: 212 PAQGR-VSRRLSPRKVSTCTDHE------LENH----SMYCVQCKMPVCYQC-LEEGKHS 259
                 V+++L   ++ + T HE       ENH    S++C  CK  +C+QC L  G H 
Sbjct: 66  CRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHG 125

Query: 260 SHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQ 319
            H  K L  +++ H +++++ +  L  R       L++L ++VQ+++ N    EA   A+
Sbjct: 126 GHTFKPLAEIYEQHVTKVNEEVAKLRRR-------LMELISLVQEVERN---VEAVRNAK 175

Query: 320 CDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIK 375
            D  +  +      ++AR++ + ++KL  +  Q       L Q T L+E  L+ ++
Sbjct: 176 -DERVREIRNAVEMMIARLDTQLKNKLITLMGQ----KTSLTQETELLESLLQEVE 226


>gi|15147333 tripartite motif-containing 37 protein [Homo sapiens]
          Length = 964

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 60/236 (25%), Positives = 109/236 (46%), Gaps = 36/236 (15%)

Query: 160 QSKAAALKCQLCEKAPKEATVMCEQCDVFYCDPC--------RLRCHPPRGPLAKHRLVP 211
           +S A   +C +C +  ++A  +C  C    C  C        R +C   R PL    LV 
Sbjct: 7   ESIAEVFRCFICMEKLRDAR-LCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVN 65

Query: 212 PAQGR-VSRRLSPRKVSTCTDHE------LENH----SMYCVQCKMPVCYQC-LEEGKHS 259
                 V+++L   ++ + T HE       ENH    S++C  CK  +C+QC L  G H 
Sbjct: 66  CRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHG 125

Query: 260 SHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQ 319
            H  K L  +++ H +++++ +  L  R       L++L ++VQ+++ N    EA   A+
Sbjct: 126 GHTFKPLAEIYEQHVTKVNEEVAKLRRR-------LMELISLVQEVERN---VEAVRNAK 175

Query: 320 CDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIK 375
            D  +  +      ++AR++ + ++KL  +  Q       L Q T L+E  L+ ++
Sbjct: 176 -DERVREIRNAVEMMIARLDTQLKNKLITLMGQ----KTSLTQETELLESLLQEVE 226


>gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]
          Length = 744

 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 45/205 (21%), Positives = 83/205 (40%), Gaps = 3/205 (1%)

Query: 225 KVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGL 284
           K  +C +H+      YC  C+  +C +C E G+H+ H    L  + + HK+ L   L+ +
Sbjct: 114 KPLSCPNHDGNVMEFYCQSCETAMCRECTE-GEHAEHPTVPLKDVVEQHKASLQVQLDAV 172

Query: 285 SDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEH 344
           + R  E    L  +  ++ Q+          + +  D L   LN RK+ LL  +   +  
Sbjct: 173 NKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGL 232

Query: 345 KLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGT 404
           K KV++ Q+               +  + +     +  L +   +  +++   DQ     
Sbjct: 233 KHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQ--DFP 290

Query: 405 LTPRMTTDFDLSLDNSPLLQSIHQL 429
           L PR     D  ++   L +SIH L
Sbjct: 291 LHPRENDQLDFIVETEGLKKSIHNL 315



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 12/31 (38%), Positives = 18/31 (58%)

Query: 8  LKCPVCGSFYREPIILPCSHNLCQACARNIL 38
          L C +C   Y+ P +LPC H  C+ C +N +
Sbjct: 21 LICSICLERYKNPKVLPCLHTFCERCLQNYI 51


>gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]
          Length = 771

 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 45/205 (21%), Positives = 83/205 (40%), Gaps = 3/205 (1%)

Query: 225 KVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGL 284
           K  +C +H+      YC  C+  +C +C E G+H+ H    L  + + HK+ L   L+ +
Sbjct: 141 KPLSCPNHDGNVMEFYCQSCETAMCRECTE-GEHAEHPTVPLKDVVEQHKASLQVQLDAV 199

Query: 285 SDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEH 344
           + R  E    L  +  ++ Q+          + +  D L   LN RK+ LL  +   +  
Sbjct: 200 NKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGL 259

Query: 345 KLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGT 404
           K KV++ Q+               +  + +     +  L +   +  +++   DQ     
Sbjct: 260 KHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQ--DFP 317

Query: 405 LTPRMTTDFDLSLDNSPLLQSIHQL 429
           L PR     D  ++   L +SIH L
Sbjct: 318 LHPRENDQLDFIVETEGLKKSIHNL 342



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 12/31 (38%), Positives = 18/31 (58%)

Query: 8  LKCPVCGSFYREPIILPCSHNLCQACARNIL 38
          L C +C   Y+ P +LPC H  C+ C +N +
Sbjct: 48 LICSICLERYKNPKVLPCLHTFCERCLQNYI 78


>gi|15208643 ADP-ribosylation factor domain protein 1 isoform gamma
           [Homo sapiens]
          Length = 546

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 66/291 (22%), Positives = 112/291 (38%), Gaps = 48/291 (16%)

Query: 126 ITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQ---------------SKAAALKCQL 170
           I CP   +   L D G+ G  KN  L  +++R Q                S  + ++C  
Sbjct: 70  IRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGISGESIIRCD- 128

Query: 171 CEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCT 230
            E     A+V C  C    C  C    H  +  LAKHR VP A         P + + C+
Sbjct: 129 -EDEAHLASVYCTVCATHLCSECSQVTHSTK-TLAKHRRVPLAD-------KPHEKTMCS 179

Query: 231 DHELENHSMYCV----QCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSD 286
            H++      C+    Q    +C  C E GKH  H+   L       ++ +    + +  
Sbjct: 180 QHQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRT 239

Query: 287 RAKEAKEFLVQLRNMVQQIQ--ENSVE-----------------FEACLVAQCDALIDAL 327
             +E  ++  +L  +VQ I+  E  VE                   +C+ A    L + L
Sbjct: 240 FTEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETL 299

Query: 328 NRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKEND 378
            R++   L+ V+     KL  +R Q    T+ L + +    +C + ++++D
Sbjct: 300 CRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCEKTLQQDD 350


>gi|15208641 ADP-ribosylation factor domain protein 1 isoform beta
           [Homo sapiens]
          Length = 569

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 66/291 (22%), Positives = 112/291 (38%), Gaps = 48/291 (16%)

Query: 126 ITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQ---------------SKAAALKCQL 170
           I CP   +   L D G+ G  KN  L  +++R Q                S  + ++C  
Sbjct: 70  IRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGISGESIIRCD- 128

Query: 171 CEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCT 230
            E     A+V C  C    C  C    H  +  LAKHR VP A         P + + C+
Sbjct: 129 -EDEAHLASVYCTVCATHLCSECSQVTHSTK-TLAKHRRVPLAD-------KPHEKTMCS 179

Query: 231 DHELENHSMYCV----QCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSD 286
            H++      C+    Q    +C  C E GKH  H+   L       ++ +    + +  
Sbjct: 180 QHQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRT 239

Query: 287 RAKEAKEFLVQLRNMVQQIQ--ENSVE-----------------FEACLVAQCDALIDAL 327
             +E  ++  +L  +VQ I+  E  VE                   +C+ A    L + L
Sbjct: 240 FTEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETL 299

Query: 328 NRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKEND 378
            R++   L+ V+     KL  +R Q    T+ L + +    +C + ++++D
Sbjct: 300 CRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCEKTLQQDD 350


>gi|4502197 ADP-ribosylation factor domain protein 1 isoform alpha
           [Homo sapiens]
          Length = 574

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 66/291 (22%), Positives = 112/291 (38%), Gaps = 48/291 (16%)

Query: 126 ITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQ---------------SKAAALKCQL 170
           I CP   +   L D G+ G  KN  L  +++R Q                S  + ++C  
Sbjct: 70  IRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGISGESIIRCD- 128

Query: 171 CEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCT 230
            E     A+V C  C    C  C    H  +  LAKHR VP A         P + + C+
Sbjct: 129 -EDEAHLASVYCTVCATHLCSECSQVTHSTK-TLAKHRRVPLAD-------KPHEKTMCS 179

Query: 231 DHELENHSMYCV----QCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSD 286
            H++      C+    Q    +C  C E GKH  H+   L       ++ +    + +  
Sbjct: 180 QHQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRT 239

Query: 287 RAKEAKEFLVQLRNMVQQIQ--ENSVE-----------------FEACLVAQCDALIDAL 327
             +E  ++  +L  +VQ I+  E  VE                   +C+ A    L + L
Sbjct: 240 FTEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETL 299

Query: 328 NRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKEND 378
            R++   L+ V+     KL  +R Q    T+ L + +    +C + ++++D
Sbjct: 300 CRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCEKTLQQDD 350


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,979,704
Number of Sequences: 37866
Number of extensions: 1475578
Number of successful extensions: 6941
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 215
Number of HSP's successfully gapped in prelim test: 167
Number of HSP's that attempted gapping in prelim test: 5941
Number of HSP's gapped (non-prelim): 1010
length of query: 710
length of database: 18,247,518
effective HSP length: 109
effective length of query: 601
effective length of database: 14,120,124
effective search space: 8486194524
effective search space used: 8486194524
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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