Search of human proteins with 190341097

Search of human proteins with 190341097

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|190341097 rhomboid family 1 [Homo sapiens]
         (855 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|190341097 rhomboid family 1 [Homo sapiens]                        1766   0.0  
gi|93352558 rhomboid, veinlet-like 6 isoform 2 [Homo sapiens]         971   0.0  
gi|93352556 rhomboid, veinlet-like 6 isoform 1 [Homo sapiens]         965   0.0  
gi|54144654 rhomboid protease 2 [Homo sapiens]                         65   2e-10
gi|21264326 rhomboid protease 3 [Homo sapiens]                         54   5e-07
gi|4506525 rhomboid protease 1 [Homo sapiens]                          43   0.001
gi|25121980 dispatched B [Homo sapiens]                                42   0.002
gi|29029632 anaplastic lymphoma kinase [Homo sapiens]                  38   0.035
gi|20127652 presenilin associated, rhomboid-like isoform 1 prepr...    35   0.39 
gi|41281943 hypothetical protein LOC753 isoform alpha 1 [Homo sa...    33   1.1  
gi|41281957 hypothetical protein LOC753 isoform alpha 2 [Homo sa...    33   1.1  
gi|4757884 hypothetical protein LOC753 isoform beta 1 [Homo sapi...    33   1.1  
gi|41281948 hypothetical protein LOC753 isoform beta 2 [Homo sap...    33   1.1  
gi|51093710 hypothetical protein LOC753 isoform gamma 2 [Homo sa...    33   1.1  
gi|51093708 hypothetical protein LOC753 isoform gamma 1 [Homo sa...    33   1.1  
gi|38044290 zinc finger, CCHC domain containing 8 [Homo sapiens]       33   1.1  
gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13...    33   1.5  
gi|169213433 PREDICTED: hypothetical protein LOC646698 [Homo sap...    32   2.5  
gi|40317620 transmembrane prostate androgen-induced protein isof...    32   2.5  
gi|40317618 transmembrane prostate androgen-induced protein isof...    32   2.5  
gi|40317616 transmembrane prostate androgen-induced protein isof...    32   2.5  
gi|21361841 transmembrane prostate androgen-induced protein isof...    32   2.5  
gi|169214102 PREDICTED: similar to hCG92381 [Homo sapiens]             31   5.6  
gi|169214479 PREDICTED: similar to hCG92381 [Homo sapiens]             31   5.6  
gi|67551265 transcription factor ELYS [Homo sapiens]                   31   5.6  
gi|56790897 LMBR1 domain containing 2 [Homo sapiens]                   31   5.6  
gi|195972909 nasal embryonic LHRH factor isoform a [Homo sapiens]      30   7.3  
gi|46397396 nasal embryonic LHRH factor isoform b [Homo sapiens]       30   7.3  
gi|239753110 PREDICTED: doublecortin domain-containing protein E...    30   9.5  
gi|239747673 PREDICTED: doublecortin domain-containing protein E...    30   9.5  

>gi|190341097 rhomboid family 1 [Homo sapiens]
          Length = 855

 Score = 1766 bits (4573), Expect = 0.0
 Identities = 855/855 (100%), Positives = 855/855 (100%)

Query: 1   MSEARRDSTSSLQRKKPPWLKLDIPSAVPLTAEEPSFLQPLRRQAFLRSVSMPAETAHIS 60
           MSEARRDSTSSLQRKKPPWLKLDIPSAVPLTAEEPSFLQPLRRQAFLRSVSMPAETAHIS
Sbjct: 1   MSEARRDSTSSLQRKKPPWLKLDIPSAVPLTAEEPSFLQPLRRQAFLRSVSMPAETAHIS 60

Query: 61  SPHHELRRPVLQRQTSITQTIRRGTADWFGVSKDSDSTQKWQRKSIRHCSQRYGKLKPQV 120
           SPHHELRRPVLQRQTSITQTIRRGTADWFGVSKDSDSTQKWQRKSIRHCSQRYGKLKPQV
Sbjct: 61  SPHHELRRPVLQRQTSITQTIRRGTADWFGVSKDSDSTQKWQRKSIRHCSQRYGKLKPQV 120

Query: 121 LRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQKIIDPLARGRAFRVADDTAEGLSAPHT 180
           LRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQKIIDPLARGRAFRVADDTAEGLSAPHT
Sbjct: 121 LRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQKIIDPLARGRAFRVADDTAEGLSAPHT 180

Query: 181 PVTPGAASLCSFSSSRSGFHRLPRRRKRESVAKMSFRAAAALMKGRSVRDGTFRRAQRRS 240
           PVTPGAASLCSFSSSRSGFHRLPRRRKRESVAKMSFRAAAALMKGRSVRDGTFRRAQRRS
Sbjct: 181 PVTPGAASLCSFSSSRSGFHRLPRRRKRESVAKMSFRAAAALMKGRSVRDGTFRRAQRRS 240

Query: 241 FTPASFLEEDTTDFPDELDTSFFAREGILHEELSTYPDEVFESPSEAALKDWEKAPEQAD 300
           FTPASFLEEDTTDFPDELDTSFFAREGILHEELSTYPDEVFESPSEAALKDWEKAPEQAD
Sbjct: 241 FTPASFLEEDTTDFPDELDTSFFAREGILHEELSTYPDEVFESPSEAALKDWEKAPEQAD 300

Query: 301 LTGGALDRSELERSHLMLPLERGWRKQKEGAAAPQPKVRLRQEVVSTAGPRRGQRIAVPV 360
           LTGGALDRSELERSHLMLPLERGWRKQKEGAAAPQPKVRLRQEVVSTAGPRRGQRIAVPV
Sbjct: 301 LTGGALDRSELERSHLMLPLERGWRKQKEGAAAPQPKVRLRQEVVSTAGPRRGQRIAVPV 360

Query: 361 RKLFAREKRPYGLGMVGRLTNRTYRKRIDSFVKRQIEDMDDHRPFFTYWLTFVHSLVTIL 420
           RKLFAREKRPYGLGMVGRLTNRTYRKRIDSFVKRQIEDMDDHRPFFTYWLTFVHSLVTIL
Sbjct: 361 RKLFAREKRPYGLGMVGRLTNRTYRKRIDSFVKRQIEDMDDHRPFFTYWLTFVHSLVTIL 420

Query: 421 AVCIYGIAPVGFSQHETVDSVLRNRGVYENVKYVQQENFWIGPSSEALIHLGAKFSPCMR 480
           AVCIYGIAPVGFSQHETVDSVLRNRGVYENVKYVQQENFWIGPSSEALIHLGAKFSPCMR
Sbjct: 421 AVCIYGIAPVGFSQHETVDSVLRNRGVYENVKYVQQENFWIGPSSEALIHLGAKFSPCMR 480

Query: 481 QDPQVHSFIRSAREREKHSACCVRNDRSGCVQTSEEECSSTLAVWVKWPIHPSAPELAGH 540
           QDPQVHSFIRSAREREKHSACCVRNDRSGCVQTSEEECSSTLAVWVKWPIHPSAPELAGH
Sbjct: 481 QDPQVHSFIRSAREREKHSACCVRNDRSGCVQTSEEECSSTLAVWVKWPIHPSAPELAGH 540

Query: 541 KRQFGSVCHQDPRVCDEPSSEDPHEWPEDITKWPICTKNSAGNHTNHPHMDCVITGRPCC 600
           KRQFGSVCHQDPRVCDEPSSEDPHEWPEDITKWPICTKNSAGNHTNHPHMDCVITGRPCC
Sbjct: 541 KRQFGSVCHQDPRVCDEPSSEDPHEWPEDITKWPICTKNSAGNHTNHPHMDCVITGRPCC 600

Query: 601 IGTKGRCEITSREYCDFMRGYFHEEATLCSQVHCMDDVCGLLPFLNPEVPDQFYRLWLSL 660
           IGTKGRCEITSREYCDFMRGYFHEEATLCSQVHCMDDVCGLLPFLNPEVPDQFYRLWLSL
Sbjct: 601 IGTKGRCEITSREYCDFMRGYFHEEATLCSQVHCMDDVCGLLPFLNPEVPDQFYRLWLSL 660

Query: 661 FLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLASAIFLPYRAEVGPA 720
           FLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLASAIFLPYRAEVGPA
Sbjct: 661 FLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLASAIFLPYRAEVGPA 720

Query: 721 GSQFGILACLFVELFQSWQILARPWRAFFKLLAVVLFLFTFGLLPWIDNFAHISGFISGL 780
           GSQFGILACLFVELFQSWQILARPWRAFFKLLAVVLFLFTFGLLPWIDNFAHISGFISGL
Sbjct: 721 GSQFGILACLFVELFQSWQILARPWRAFFKLLAVVLFLFTFGLLPWIDNFAHISGFISGL 780

Query: 781 FLSFAFLPYISFGKFDLYRKRCQIIIFQVVFLGLLAGLVVLFYVYPVRCEWCEFLTCIPF 840
           FLSFAFLPYISFGKFDLYRKRCQIIIFQVVFLGLLAGLVVLFYVYPVRCEWCEFLTCIPF
Sbjct: 781 FLSFAFLPYISFGKFDLYRKRCQIIIFQVVFLGLLAGLVVLFYVYPVRCEWCEFLTCIPF 840

Query: 841 TDKFCEKYELDAQLH 855
           TDKFCEKYELDAQLH
Sbjct: 841 TDKFCEKYELDAQLH 855


>gi|93352558 rhomboid, veinlet-like 6 isoform 2 [Homo sapiens]
          Length = 827

 Score =  971 bits (2511), Expect = 0.0
 Identities = 496/858 (57%), Positives = 603/858 (70%), Gaps = 55/858 (6%)

Query: 8   STSSLQRKKPPWLKLDIPSAVPLT---AEEPSFLQPLRRQAFLRSVSMPAETAHISSPHH 64
           S+S LQ +KPP L + IP     T    E+ S L   +  A+L+SVS+    +       
Sbjct: 15  SSSRLQSRKPPNLSITIPPPEKETQAPGEQDSMLPERKNPAYLKSVSLQEPRSRWQESSE 74

Query: 65  ELRRPVLQRQTSITQTIRRGTADWFGVSKDSDST-QKWQRKSIRHCSQRYGKLKPQVLRE 123
             +RP  +RQ S++Q+IR+G A WFGVS D +   Q+WQR+S+ HCS RYG+LK    R+
Sbjct: 75  --KRPGFRRQASLSQSIRKGAAQWFGVSGDWEGQRQQWQRRSLHHCSMRYGRLKASCQRD 132

Query: 124 LDLPSQDNVSLTSTETPPPLYVGPCQLGMQKIIDPLARGRAFRVADDTAEGLSAPHTPVT 183
           L+LPSQ+  S   TE+P P     C+  M KI+DPLARGRAFR  ++  +   APH P+T
Sbjct: 133 LELPSQEAPSFQGTESPKP-----CK--MPKIVDPLARGRAFRHPEEM-DRPHAPHPPLT 184

Query: 184 PGAASLCSFSSSRSGFHRLPRRRKRESVAKMSFRAAAALMKGRSVRDGTFRRAQ--RRSF 241
           PG  SL SF+S RSG+  LPRR KR SVA MS +AAAAL+KGRSV D T +R +  +RSF
Sbjct: 185 PGVLSLTSFTSVRSGYSHLPRR-KRMSVAHMSLQAAAALLKGRSVLDATGQRCRVVKRSF 243

Query: 242 TPASFLEEDTTDFPDELDTSFFAREGILHEELSTYPDEVFESPSEAALKDWEKAPEQADL 301
              SFLEED  D  D  D+SFF++E     E+S+ PD+VFESP  +A   +   P  A  
Sbjct: 244 AFPSFLEEDVVDGADTFDSSFFSKE-----EMSSMPDDVFESPPLSA-SYFRGIPHSA-- 295

Query: 302 TGGALDRSELERSHLMLPLERGWRKQKEGAAAPQPKVRLRQEVVSTAGPRRGQRIAVPVR 361
                  S +    + +PL       KE   AP P            GPRRG+RIA  V+
Sbjct: 296 -------SPVSPDGVQIPL-------KEYGRAPVP------------GPRRGKRIASKVK 329

Query: 362 KL-FAREKRPYGLGMVGRLTNRTYRKRIDSFVKRQIEDMDDHRPFFTYWLTFVHSLVTIL 420
              F R+KR YGLG+VG   NR+YR+ I S V+RQ+E  D HRP+FTYWLTFVH ++T+L
Sbjct: 330 HFAFDRKKRHYGLGVVGNWLNRSYRRSISSTVQRQLESFDSHRPYFTYWLTFVHVIITLL 389

Query: 421 AVCIYGIAPVGFSQHETVDSVLRNRGVYENVKYVQQENFWIGPSSEALIHLGAKFSPCMR 480
            +C YGIAPVGF+QH T   VLRN+GVYE+VKY+QQENFW+GPSS  LIHLGAKFSPC+R
Sbjct: 390 VICTYGIAPVGFAQHVTTQLVLRNKGVYESVKYIQQENFWVGPSSIDLIHLGAKFSPCIR 449

Query: 481 QDPQVHSFIRSAREREKHSACCVRNDRSGCVQTSEEECSSTLAVWVKWPIHPSAP---EL 537
           +D Q+   +   R+ E+ S CCV+ND SGC+QT  ++CS TLA +VKW      P     
Sbjct: 450 KDGQIEQLVLRERDLERDSGCCVQNDHSGCIQTQRKDCSETLATFVKWQDDTGPPMDKSD 509

Query: 538 AGHKRQFGSVCHQDPRVCDEPSSEDPHEWPEDITKWPICTKNSAGNHTNHPHMDCVITGR 597
            G KR  G+VCHQDPR C+EP+S   H WP+DITKWPICT+ +  NHT   HMDC I GR
Sbjct: 510 LGQKRTSGAVCHQDPRTCEEPASSGAHIWPDDITKWPICTEQARSNHTGFLHMDCEIKGR 569

Query: 598 PCCIGTKGRCEITSREYCDFMRGYFHEEATLCSQVHCMDDVCGLLPFLNPEVPDQFYRLW 657
           PCCIGTKG CEIT+REYC+FM GYFHEEATLCSQVHC+D VCGLLPFLNPEVPDQFYRLW
Sbjct: 570 PCCIGTKGSCEITTREYCEFMHGYFHEEATLCSQVHCLDKVCGLLPFLNPEVPDQFYRLW 629

Query: 658 LSLFLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLASAIFLPYRAEV 717
           LSLFLHAG++HCLVS+ FQMT+LRDLEKLAGWHRIAII++LSG+TGNLASAIFLPYRAEV
Sbjct: 630 LSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPYRAEV 689

Query: 718 GPAGSQFGILACLFVELFQSWQILARPWRAFFKLLAVVLFLFTFGLLPWIDNFAHISGFI 777
           GPAGSQFG+LACLFVELFQSW +L RPW+AF  L A+VLFLF  GLLPWIDN AHI GF+
Sbjct: 690 GPAGSQFGLLACLFVELFQSWPLLERPWKAFLNLSAIVLFLFICGLLPWIDNIAHIFGFL 749

Query: 778 SGLFLSFAFLPYISFGKFDLYRKRCQIIIFQVVFLGLLAGLVVLFYVYPVRCEWCEFLTC 837
           SGL L+FAFLPYI+FG  D YRKR  I++  + F GL A LV+  Y+YP+   W E LTC
Sbjct: 750 SGLLLAFAFLPYITFGTSDKYRKRALILVSLLAFAGLFAALVLWLYIYPINWPWIEHLTC 809

Query: 838 IPFTDKFCEKYELDAQLH 855
            PFT +FCEKYELD  LH
Sbjct: 810 FPFTSRFCEKYELDQVLH 827


>gi|93352556 rhomboid, veinlet-like 6 isoform 1 [Homo sapiens]
          Length = 856

 Score =  965 bits (2495), Expect = 0.0
 Identities = 500/887 (56%), Positives = 607/887 (68%), Gaps = 84/887 (9%)

Query: 8   STSSLQRKKPPWLKLDIP-------------SAVP-------------------LTAEEP 35
           S+S LQ +KPP L + IP             S +P                    TA  P
Sbjct: 15  SSSRLQSRKPPNLSITIPPPEKETQAPGEQDSMLPEGFQNRRLKKSQPRTWASHTTACPP 74

Query: 36  SFLQPLRRQAFLRSVSMPAETAHISSPHHELRRPVLQRQTSITQTIRRGTADWFGVSKDS 95
           SFL   +  A+L+SVS+    +         +RP  +RQ S++Q+IR+G A WFGVS D 
Sbjct: 75  SFLPKRKNPAYLKSVSLQEPRSRWQESSE--KRPGFRRQASLSQSIRKGAAQWFGVSGDW 132

Query: 96  DST-QKWQRKSIRHCSQRYGKLKPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQK 154
           +   Q+WQR+S+ HCS RYG+LK    R+L+LPSQ+  S   TE+P P     C+  M K
Sbjct: 133 EGQRQQWQRRSLHHCSMRYGRLKASCQRDLELPSQEAPSFQGTESPKP-----CK--MPK 185

Query: 155 IIDPLARGRAFRVADDTAEGLSAPHTPVTPGAASLCSFSSSRSGFHRLPRRRKRESVAKM 214
           I+DPLARGRAFR  ++  +   APH P+TPG  SL SF+S RSG+  LPRR KR SVA M
Sbjct: 186 IVDPLARGRAFRHPEEM-DRPHAPHPPLTPGVLSLTSFTSVRSGYSHLPRR-KRMSVAHM 243

Query: 215 SFRAAAALMKGRSVRDGTFRRAQ--RRSFTPASFLEEDTTDFPDELDTSFFAREGILHEE 272
           S +AAAAL+KGRSV D T +R +  +RSF   SFLEED  D  D  D+SFF++E     E
Sbjct: 244 SLQAAAALLKGRSVLDATGQRCRVVKRSFAFPSFLEEDVVDGADTFDSSFFSKE-----E 298

Query: 273 LSTYPDEVFESPSEAALKDWEKAPEQADLTGGALDRSELERSHLMLPLERGWRKQKEGAA 332
           +S+ PD+VFESP  +A   +   P  A         S +    + +PL       KE   
Sbjct: 299 MSSMPDDVFESPPLSA-SYFRGIPHSA---------SPVSPDGVQIPL-------KEYGR 341

Query: 333 APQPKVRLRQEVVSTAGPRRGQRIAVPVRKL-FAREKRPYGLGMVGRLTNRTYRKRIDSF 391
           AP P            GPRRG+RIA  V+   F R+KR YGLG+VG   NR+YR+ I S 
Sbjct: 342 APVP------------GPRRGKRIASKVKHFAFDRKKRHYGLGVVGNWLNRSYRRSISST 389

Query: 392 VKRQIEDMDDHRPFFTYWLTFVHSLVTILAVCIYGIAPVGFSQHETVDSVLRNRGVYENV 451
           V+RQ+E  D HRP+FTYWLTFVH ++T+L +C YGIAPVGF+QH T   VLRN+GVYE+V
Sbjct: 390 VQRQLESFDSHRPYFTYWLTFVHVIITLLVICTYGIAPVGFAQHVTTQLVLRNKGVYESV 449

Query: 452 KYVQQENFWIGPSSEALIHLGAKFSPCMRQDPQVHSFIRSAREREKHSACCVRNDRSGCV 511
           KY+QQENFW+GPSS  LIHLGAKFSPC+R+D Q+   +   R+ E+ S CCV+ND SGC+
Sbjct: 450 KYIQQENFWVGPSSIDLIHLGAKFSPCIRKDGQIEQLVLRERDLERDSGCCVQNDHSGCI 509

Query: 512 QTSEEECSSTLAVWVKWPIHPSAP---ELAGHKRQFGSVCHQDPRVCDEPSSEDPHEWPE 568
           QT  ++CS TLA +VKW      P      G KR  G+VCHQDPR C+EP+S   H WP+
Sbjct: 510 QTQRKDCSETLATFVKWQDDTGPPMDKSDLGQKRTSGAVCHQDPRTCEEPASSGAHIWPD 569

Query: 569 DITKWPICTKNSAGNHTNHPHMDCVITGRPCCIGTKGRCEITSREYCDFMRGYFHEEATL 628
           DITKWPICT+ +  NHT   HMDC I GRPCCIGTKG CEIT+REYC+FM GYFHEEATL
Sbjct: 570 DITKWPICTEQARSNHTGFLHMDCEIKGRPCCIGTKGSCEITTREYCEFMHGYFHEEATL 629

Query: 629 CSQVHCMDDVCGLLPFLNPEVPDQFYRLWLSLFLHAGILHCLVSICFQMTVLRDLEKLAG 688
           CSQVHC+D VCGLLPFLNPEVPDQFYRLWLSLFLHAG++HCLVS+ FQMT+LRDLEKLAG
Sbjct: 630 CSQVHCLDKVCGLLPFLNPEVPDQFYRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAG 689

Query: 689 WHRIAIIYLLSGVTGNLASAIFLPYRAEVGPAGSQFGILACLFVELFQSWQILARPWRAF 748
           WHRIAII++LSG+TGNLASAIFLPYRAEVGPAGSQFG+LACLFVELFQSW +L RPW+AF
Sbjct: 690 WHRIAIIFILSGITGNLASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWPLLERPWKAF 749

Query: 749 FKLLAVVLFLFTFGLLPWIDNFAHISGFISGLFLSFAFLPYISFGKFDLYRKRCQIIIFQ 808
             L A+VLFLF  GLLPWIDN AHI GF+SGL L+FAFLPYI+FG  D YRKR  I++  
Sbjct: 750 LNLSAIVLFLFICGLLPWIDNIAHIFGFLSGLLLAFAFLPYITFGTSDKYRKRALILVSL 809

Query: 809 VVFLGLLAGLVVLFYVYPVRCEWCEFLTCIPFTDKFCEKYELDAQLH 855
           + F GL A LV+  Y+YP+   W E LTC PFT +FCEKYELD  LH
Sbjct: 810 LAFAGLFAALVLWLYIYPINWPWIEHLTCFPFTSRFCEKYELDQVLH 856


>gi|54144654 rhomboid protease 2 [Homo sapiens]
          Length = 303

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 38/154 (24%), Positives = 79/154 (51%), Gaps = 12/154 (7%)

Query: 643 PFL-NPEVPDQFYRLWLSLFLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGV 701
           PF+ +PE  ++ +R    + +HAG+ H L ++C Q+ +   LE +    R+ ++YL   +
Sbjct: 109 PFIYSPEKREEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHKGLRVGLVYLAGVI 168

Query: 702 TGNLASAIFLPYRAEVGPAGSQFGILACLFVELFQSWQILARPWRAFFKLLAVVLFLFTF 761
            G+LAS+IF P R  VG +G  + ++   F+ +  ++Q +   +  F  L+ +++ +   
Sbjct: 169 AGSLASSIFDPLRYLVGASGGVYALMGGYFMNVLVNFQEMIPAFGIFRLLIIILIIVLDM 228

Query: 762 GLLPW-----------IDNFAHISGFISGLFLSF 784
           G   +           +   AHI+G  +G+ + +
Sbjct: 229 GFALYRRFFVPEDGSPVSFAAHIAGGFAGMSIGY 262


>gi|21264326 rhomboid protease 3 [Homo sapiens]
          Length = 404

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 29/122 (23%), Positives = 60/122 (49%)

Query: 646 NPEVPDQFYRLWLSLFLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNL 705
           +P++  Q +R    +F+HAGI H  +++  Q+ V   LE + G  RI ++Y+   V G+L
Sbjct: 204 HPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSL 263

Query: 706 ASAIFLPYRAEVGPAGSQFGILACLFVELFQSWQILARPWRAFFKLLAVVLFLFTFGLLP 765
           A ++       VG +G  + +++     +  +W  +   ++     +A++     FG   
Sbjct: 264 AVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSMEFGRAV 323

Query: 766 WI 767
           W+
Sbjct: 324 WL 325


>gi|4506525 rhomboid protease 1 [Homo sapiens]
          Length = 438

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 30/147 (20%), Positives = 61/147 (41%), Gaps = 13/147 (8%)

Query: 654 YRLWLSLFLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLASAIFLPY 713
           +R    +F+H G+     +   Q+ +   LE + G  RI+++YL   + G+L  +I    
Sbjct: 246 WRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMR 305

Query: 714 RAEVGPAGSQFGILACLFVELFQSWQILARPWRAFFKLLAVVLFLFTFGLLPWI------ 767
              VG +G  + + +     +  +W  +  P++    +LA+V      G   W+      
Sbjct: 306 APVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPL 365

Query: 768 -------DNFAHISGFISGLFLSFAFL 787
                     AH++G + G+ +    L
Sbjct: 366 PASGPQPSFMAHLAGAVVGVSMGLTIL 392


>gi|25121980 dispatched B [Homo sapiens]
          Length = 1401

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 43/162 (26%), Positives = 71/162 (43%), Gaps = 33/162 (20%)

Query: 428 APVGFSQHETVDSVLRNRGVYENVKYVQQENFWIGP-------------SSEALIHLGAK 474
           AP G +Q    +S +R R + E ++  +QENF+ GP             SS +L +L A 
Sbjct: 250 APRGSAQ----ESAVRPRRMVEPLEDRRQENFFCGPPEKSYAKLVFMSTSSGSLWNLHAI 305

Query: 475 FSPCMRQDPQV--HSFIRSAREREKHSACC----------VRNDRSGCVQTSEEECSSTL 522
            S C  +  Q+  H+   +  +R   + CC          V ++RS C+ T++ + + TL
Sbjct: 306 HSMCRMEQDQIRSHTSFGALCQRTAANQCCPSWSLGNYLAVLSNRSSCLDTTQADAARTL 365

Query: 523 AVWVKWPI--HPSA--PELAGHKRQFGSVCHQDPRVCDEPSS 560
           A+     +  H  A  P   G  +     C Q P  C + S+
Sbjct: 366 ALLRTCALYYHSGALVPSCLGPGQNKSPRCAQVPTKCSQSSA 407


>gi|29029632 anaplastic lymphoma kinase [Homo sapiens]
          Length = 1620

 Score = 38.1 bits (87), Expect = 0.035
 Identities = 20/80 (25%), Positives = 39/80 (48%)

Query: 95  SDSTQKWQRKSIRHCSQRYGKLKPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQK 154
           S  T +WQ ++++    +  +    +L   D+P+ ++ ++TS   P P+   PC+L M  
Sbjct: 495 SPHTPQWQVRTLKDARFQDHQDHALLLSTTDVPASESATVTSATFPAPIKSSPCELRMSW 554

Query: 155 IIDPLARGRAFRVADDTAEG 174
           +I  + RG    V  +   G
Sbjct: 555 LIRGVLRGNVSLVLVENKTG 574


>gi|20127652 presenilin associated, rhomboid-like isoform 1
           preproprotein [Homo sapiens]
          Length = 379

 Score = 34.7 bits (78), Expect = 0.39
 Identities = 31/154 (20%), Positives = 67/154 (43%), Gaps = 17/154 (11%)

Query: 658 LSLFLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLASAIFL----PY 713
           LS F H  + H   ++    +    +  + G  +   +YL +GV  N  S +       Y
Sbjct: 211 LSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRY 270

Query: 714 RAEVGPAGSQFGILACLFVELFQS-WQILARPWRAFF--KLLAVVLFLFTFGLL---PWI 767
              +G +G+   +LA +  ++ +    I+  P   F     L  ++ + T G++    + 
Sbjct: 271 GPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFF 330

Query: 768 DNFAHISGFISGLFLSFAFLPYISFGKFDLYRKR 801
           D+ AH+ G + G++       Y+++G   +++ R
Sbjct: 331 DHAAHLGGALFGIW-------YVTYGHELIWKNR 357


>gi|41281943 hypothetical protein LOC753 isoform alpha 1 [Homo
           sapiens]
          Length = 306

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 3/42 (7%)

Query: 112 RYGKLKPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQ 153
           R+    P V  E+DLP    +SL+  E PPP Y GPC L ++
Sbjct: 154 RFQPTYPYVQHEIDLPP--TISLSDGEEPPP-YQGPCTLQLR 192


>gi|41281957 hypothetical protein LOC753 isoform alpha 2 [Homo
           sapiens]
          Length = 288

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 3/42 (7%)

Query: 112 RYGKLKPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQ 153
           R+    P V  E+DLP    +SL+  E PPP Y GPC L ++
Sbjct: 136 RFQPTYPYVQHEIDLPP--TISLSDGEEPPP-YQGPCTLQLR 174


>gi|4757884 hypothetical protein LOC753 isoform beta 1 [Homo
           sapiens]
          Length = 248

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 3/42 (7%)

Query: 112 RYGKLKPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQ 153
           R+    P V  E+DLP    +SL+  E PPP Y GPC L ++
Sbjct: 96  RFQPTYPYVQHEIDLPP--TISLSDGEEPPP-YQGPCTLQLR 134


>gi|41281948 hypothetical protein LOC753 isoform beta 2 [Homo
           sapiens]
          Length = 230

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 3/42 (7%)

Query: 112 RYGKLKPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQ 153
           R+    P V  E+DLP    +SL+  E PPP Y GPC L ++
Sbjct: 78  RFQPTYPYVQHEIDLPP--TISLSDGEEPPP-YQGPCTLQLR 116


>gi|51093710 hypothetical protein LOC753 isoform gamma 2 [Homo
           sapiens]
          Length = 251

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 3/42 (7%)

Query: 112 RYGKLKPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQ 153
           R+    P V  E+DLP    +SL+  E PPP Y GPC L ++
Sbjct: 99  RFQPTYPYVQHEIDLPP--TISLSDGEEPPP-YQGPCTLQLR 137


>gi|51093708 hypothetical protein LOC753 isoform gamma 1 [Homo
           sapiens]
          Length = 269

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 3/42 (7%)

Query: 112 RYGKLKPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQ 153
           R+    P V  E+DLP    +SL+  E PPP Y GPC L ++
Sbjct: 117 RFQPTYPYVQHEIDLPP--TISLSDGEEPPP-YQGPCTLQLR 155


>gi|38044290 zinc finger, CCHC domain containing 8 [Homo sapiens]
          Length = 707

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 29/132 (21%), Positives = 54/132 (40%), Gaps = 22/132 (16%)

Query: 29  PLTAEEPSFLQ----PLRRQAFLRSVSMPAETAHISS----PH--------HELRRPVLQ 72
           PL  E P   +    P   Q F   VS+  +   + +    PH        H+++   + 
Sbjct: 186 PLLNENPQLSEGWEIPKYHQVFSHIVSLEGQEIQVKAKRPKPHCFNCGSEEHQMKDCPMP 245

Query: 73  RQTSITQTIRRGTADWFGVSKDSDSTQKWQRKSIRHCSQRYGKLKPQVLRELDLPSQDNV 132
           R  +     R+   D  G + + +  Q++  + +    +R+G+ KP V+ E     QD +
Sbjct: 246 RNAARISEKRKEYMDACGEANNQNFQQRYHAEEVE---ERFGRFKPGVISE---ELQDAL 299

Query: 133 SLTSTETPPPLY 144
            +T    PP +Y
Sbjct: 300 GVTDKSLPPFIY 311


>gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13
            [Homo sapiens]
          Length = 5058

 Score = 32.7 bits (73), Expect = 1.5
 Identities = 18/65 (27%), Positives = 32/65 (49%)

Query: 726  ILACLFVELFQSWQILARPWRAFFKLLAVVLFLFTFGLLPWIDNFAHISGFISGLFLSFA 785
            +  CL V +  ++Q+ A  +R      A++L LF +  LPW+   + I       F+S+ 
Sbjct: 4513 VSVCLCVAVIVAFQLTAFTFRKNLAATALLLSLFGYATLPWMYLMSRIFSSSDVAFISYV 4572

Query: 786  FLPYI 790
             L +I
Sbjct: 4573 SLNFI 4577


>gi|169213433 PREDICTED: hypothetical protein LOC646698 [Homo
           sapiens]
          Length = 497

 Score = 32.0 bits (71), Expect = 2.5
 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 8/96 (8%)

Query: 117 KPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQKIIDPLARGRAFRVADDTAEGLS 176
           KP + ++L++  ++N  LTS E  P L  GP  +G ++  +P  R     V  DT     
Sbjct: 215 KPTLEKDLNVDREENTGLTSPE--PQLPNGPSVVGAKEGKEPKKRASVENVDADT----- 267

Query: 177 APHTPVTPGAASLCSFSSSRSGFHRLPRRRKRESVA 212
            P   V    AS  S S   +   R P+R K ++ +
Sbjct: 268 -PSACVVEREASTHSGSRGDALNLRCPKRSKPDATS 302


>gi|40317620 transmembrane prostate androgen-induced protein isoform
           c [Homo sapiens]
          Length = 237

 Score = 32.0 bits (71), Expect = 2.5
 Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 3/42 (7%)

Query: 112 RYGKLKPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQ 153
           R+    P +  E+DLP    +SL+  E PPP Y GPC L ++
Sbjct: 82  RFQPTYPYLQHEIDLPP--TISLSDGEEPPP-YQGPCTLQLR 120


>gi|40317618 transmembrane prostate androgen-induced protein isoform
           c [Homo sapiens]
          Length = 237

 Score = 32.0 bits (71), Expect = 2.5
 Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 3/42 (7%)

Query: 112 RYGKLKPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQ 153
           R+    P +  E+DLP    +SL+  E PPP Y GPC L ++
Sbjct: 82  RFQPTYPYLQHEIDLPP--TISLSDGEEPPP-YQGPCTLQLR 120


>gi|40317616 transmembrane prostate androgen-induced protein isoform
           b [Homo sapiens]
          Length = 252

 Score = 32.0 bits (71), Expect = 2.5
 Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 3/42 (7%)

Query: 112 RYGKLKPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQ 153
           R+    P +  E+DLP    +SL+  E PPP Y GPC L ++
Sbjct: 97  RFQPTYPYLQHEIDLPP--TISLSDGEEPPP-YQGPCTLQLR 135


>gi|21361841 transmembrane prostate androgen-induced protein isoform
           a [Homo sapiens]
          Length = 287

 Score = 32.0 bits (71), Expect = 2.5
 Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 3/42 (7%)

Query: 112 RYGKLKPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQ 153
           R+    P +  E+DLP    +SL+  E PPP Y GPC L ++
Sbjct: 132 RFQPTYPYLQHEIDLPP--TISLSDGEEPPP-YQGPCTLQLR 170


>gi|169214102 PREDICTED: similar to hCG92381 [Homo sapiens]
          Length = 497

 Score = 30.8 bits (68), Expect = 5.6
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 8/96 (8%)

Query: 117 KPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQKIIDPLARGRAFRVADDTAEGLS 176
           KP + ++L++  ++N  LTS E  P L  GP  +G ++  +P  R     V  DT     
Sbjct: 215 KPTLEKDLNVDREENTGLTSPE--PQLPNGPSVVGAKEGKEPKKRASVENVDADT----- 267

Query: 177 APHTPVTPGAASLCSFSSSRSGFHRLPRRRKRESVA 212
            P   V    AS  S +   +   R P+R K ++ +
Sbjct: 268 -PSACVVEREASTHSGNRGDALNLRCPKRSKPDATS 302


>gi|169214479 PREDICTED: similar to hCG92381 [Homo sapiens]
          Length = 497

 Score = 30.8 bits (68), Expect = 5.6
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 8/96 (8%)

Query: 117 KPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQKIIDPLARGRAFRVADDTAEGLS 176
           KP + ++L++  ++N  LTS E  P L  GP  +G ++  +P  R     V  DT     
Sbjct: 215 KPTLEKDLNVDREENTGLTSPE--PQLPNGPSVVGAKEGKEPKKRASVENVDADT----- 267

Query: 177 APHTPVTPGAASLCSFSSSRSGFHRLPRRRKRESVA 212
            P   V    AS  S +   +   R P+R K ++ +
Sbjct: 268 -PSACVVEREASTHSGNRGDALNLRCPKRSKPDATS 302


>gi|67551265 transcription factor ELYS [Homo sapiens]
          Length = 2266

 Score = 30.8 bits (68), Expect = 5.6
 Identities = 34/145 (23%), Positives = 58/145 (40%), Gaps = 14/145 (9%)

Query: 106  IRHCSQRYGKLKPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQKIIDPLARGRAF 165
            I   SQ+  +L   V++ +  PSQ +  +  +    PLY+      + + +   ++ +  
Sbjct: 1107 ISKASQKISRLLDLVVQPVPRPSQCSEFIQQSSMKSPLYL------VSRSLPSSSQLKGS 1160

Query: 166  RVADDTAEGLSAPHTPVTPGAASLCSFSSSRSGFHRLPRRRKRESVAKMSFRAAAALMKG 225
              A   A  L    TP+    A   + S + SGF     +    S  + +  A+ +   G
Sbjct: 1161 PQAISRASELHLLETPLVVKKAKSLAMSVTTSGFSEFTPQSILRSTLRSTPLASPSPSPG 1220

Query: 226  RSVRDGTFRRAQRRSFTPASFLEED 250
            RS         QR   T  SF+EED
Sbjct: 1221 RS--------PQRLKETRISFVEED 1237


>gi|56790897 LMBR1 domain containing 2 [Homo sapiens]
          Length = 695

 Score = 30.8 bits (68), Expect = 5.6
 Identities = 13/23 (56%), Positives = 18/23 (78%), Gaps = 2/23 (8%)

Query: 738 WQILARPWRAFFKLLAVVLFLFT 760
           W+ L RPW  F+K+LAVVL +F+
Sbjct: 377 WECLLRPW--FYKILAVVLSIFS 397


>gi|195972909 nasal embryonic LHRH factor isoform a [Homo sapiens]
          Length = 530

 Score = 30.4 bits (67), Expect = 7.3
 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 9/83 (10%)

Query: 204 RRRKRE----SVAKMSFRAAAALMKGRSVRDGTFRRAQRRSFTPASFLEEDTTDFPDELD 259
           +RRKRE    SV + +FR    ++  R V+  TF   + RSF+ +     D T  P + D
Sbjct: 246 KRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRS---WSDPT--PMKAD 300

Query: 260 TSFFAREGILHEELSTYPDEVFE 282
           TS  +R+    +      DE FE
Sbjct: 301 TSHDSRDSSDLQSSHCTLDEAFE 323


>gi|46397396 nasal embryonic LHRH factor isoform b [Homo sapiens]
          Length = 528

 Score = 30.4 bits (67), Expect = 7.3
 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 9/83 (10%)

Query: 204 RRRKRE----SVAKMSFRAAAALMKGRSVRDGTFRRAQRRSFTPASFLEEDTTDFPDELD 259
           +RRKRE    SV + +FR    ++  R V+  TF   + RSF+ +     D T  P + D
Sbjct: 244 KRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRS---WSDPT--PMKAD 298

Query: 260 TSFFAREGILHEELSTYPDEVFE 282
           TS  +R+    +      DE FE
Sbjct: 299 TSHDSRDSSDLQSSHCTLDEAFE 321


>gi|239753110 PREDICTED: doublecortin domain-containing protein
           ENSP00000382097-like [Homo sapiens]
          Length = 530

 Score = 30.0 bits (66), Expect = 9.5
 Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 7/70 (10%)

Query: 255 PDELDTSFFAREGILHEELSTYPDEVFESPSEAALKDWEKAPEQADLTGGALDRSELERS 314
           P   D+ ++A+E    E+  T  + + +  +E    D  KAP  +  T GALD  E    
Sbjct: 360 PKTQDSVYYAKE----EKKKTLAEPLVQRGAEG---DVYKAPTPSKETQGALDVKEEHNV 412

Query: 315 HLMLPLERGW 324
            L +P+++ W
Sbjct: 413 QLEVPVDQSW 422


>gi|239747673 PREDICTED: doublecortin domain-containing protein
           ENSP00000382097-like [Homo sapiens]
          Length = 714

 Score = 30.0 bits (66), Expect = 9.5
 Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 7/70 (10%)

Query: 255 PDELDTSFFAREGILHEELSTYPDEVFESPSEAALKDWEKAPEQADLTGGALDRSELERS 314
           P   D+ ++A+E    E+  T  + + +  +E    D  KAP  +  T GALD  E    
Sbjct: 413 PKTQDSVYYAKE----EKKKTLAEPLVQRGAEG---DVYKAPTPSKETQGALDVKEEHNV 465

Query: 315 HLMLPLERGW 324
            L +P+++ W
Sbjct: 466 QLEVPVDQSW 475


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,137,293
Number of Sequences: 37866
Number of extensions: 1698165
Number of successful extensions: 5414
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 5381
Number of HSP's gapped (non-prelim): 40
length of query: 855
length of database: 18,247,518
effective HSP length: 111
effective length of query: 744
effective length of database: 14,044,392
effective search space: 10449027648
effective search space used: 10449027648
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.