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Search of human proteins with 190014586
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1
[Homo sapiens]
(333 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo... 677 0.0
gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo... 660 0.0
gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo ... 660 0.0
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 203 2e-52
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 203 2e-52
gi|7705320 hepatoma-derived growth factor, related protein 3 [Ho... 187 9e-48
gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens] 185 6e-47
gi|186928819 hepatoma-derived growth factor isoform b [Homo sapi... 145 6e-35
gi|186928821 hepatoma-derived growth factor isoform c [Homo sapi... 144 1e-34
gi|110681712 hepatoma derived growth factor-like 1 [Homo sapiens] 135 5e-32
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 68 1e-11
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 64 2e-10
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 63 3e-10
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 62 5e-10
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 62 5e-10
gi|4557509 cylicin 2 [Homo sapiens] 62 9e-10
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 62 9e-10
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 61 1e-09
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 60 4e-09
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 59 5e-09
gi|157738619 smoothelin-like 1 [Homo sapiens] 59 6e-09
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 58 1e-08
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 58 1e-08
gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [H... 57 2e-08
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 56 4e-08
gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens] 56 5e-08
gi|125656165 THO complex 2 [Homo sapiens] 55 7e-08
gi|104526627 triadin [Homo sapiens] 55 7e-08
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 55 7e-08
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 54 1e-07
>gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo
sapiens]
Length = 333
Score = 677 bits (1746), Expect = 0.0
Identities = 333/333 (100%), Positives = 333/333 (100%)
Query: 1 MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP 60
MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP
Sbjct: 1 MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP 60
Query: 61 YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKE 120
YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKE
Sbjct: 61 YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKE 120
Query: 121 DTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKR 180
DTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKR
Sbjct: 121 DTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKR 180
Query: 181 GRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKE 240
GRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKE
Sbjct: 181 GRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKE 240
Query: 241 EDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRR 300
EDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRR
Sbjct: 241 EDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRR 300
Query: 301 NMLKGQHEKEAADRKRKQEEQMETEHQTTCNLQ 333
NMLKGQHEKEAADRKRKQEEQMETEHQTTCNLQ
Sbjct: 301 NMLKGQHEKEAADRKRKQEEQMETEHQTTCNLQ 333
>gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
sapiens]
Length = 530
Score = 660 bits (1704), Expect = 0.0
Identities = 326/327 (99%), Positives = 326/327 (99%)
Query: 1 MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP 60
MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP
Sbjct: 1 MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP 60
Query: 61 YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKE 120
YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKE
Sbjct: 61 YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKE 120
Query: 121 DTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKR 180
DTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKR
Sbjct: 121 DTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKR 180
Query: 181 GRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKE 240
GRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKE
Sbjct: 181 GRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKE 240
Query: 241 EDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRR 300
EDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRR
Sbjct: 241 EDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRR 300
Query: 301 NMLKGQHEKEAADRKRKQEEQMETEHQ 327
NMLKGQHEKEAADRKRKQEEQMETE Q
Sbjct: 301 NMLKGQHEKEAADRKRKQEEQMETEQQ 327
>gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
sapiens]
Length = 530
Score = 660 bits (1704), Expect = 0.0
Identities = 326/327 (99%), Positives = 326/327 (99%)
Query: 1 MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP 60
MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP
Sbjct: 1 MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP 60
Query: 61 YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKE 120
YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKE
Sbjct: 61 YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKE 120
Query: 121 DTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKR 180
DTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKR
Sbjct: 121 DTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKR 180
Query: 181 GRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKE 240
GRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKE
Sbjct: 181 GRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKE 240
Query: 241 EDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRR 300
EDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRR
Sbjct: 241 EDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRR 300
Query: 301 NMLKGQHEKEAADRKRKQEEQMETEHQ 327
NMLKGQHEKEAADRKRKQEEQMETE Q
Sbjct: 301 NMLKGQHEKEAADRKRKQEEQMETEQQ 327
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 203 bits (516), Expect = 2e-52
Identities = 128/372 (34%), Positives = 185/372 (49%), Gaps = 56/372 (15%)
Query: 1 MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP 60
M FKPGDL+FAKMKGYPHWPAR+D++ DGAVKPP NK PIFFFGTHETAFLGPKD+FP
Sbjct: 1 MPHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFP 60
Query: 61 YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKF------SSQQAATKQSNAS--SDVEVEE 112
Y + K+KYGKPNKRKGFNEGLWEI NNP + SS + ++N + SD + ++
Sbjct: 61 YDKCKDKYGKPNKRKGFNEGLWEIQNNPHASYSAPPPVSSSDSEAPEANPADGSDADEDD 120
Query: 113 KETSV--------------SKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAE-KQV 157
++ V + D+D ++ + N + + ++R RK ++ Q
Sbjct: 121 EDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQA 180
Query: 158 ETEEAGVVTTATASVNLKVSPKRGRP---AATEVKIPKPRGRPKMVKQPCPSESDIITEE 214
+ + ++S + K S + P AA P G K K P S+SD +
Sbjct: 181 SVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADS 240
Query: 215 D-------------KSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKR 261
D S KK G+K +KP +P ++ K E
Sbjct: 241 DGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPE----- 295
Query: 262 KNLAKTGVTSTSDSEEEGDDQEGEKKRKG---GRNFQTAHRRNMLK-----GQHEKEAAD 313
+ +S+SDS+ + D+ E KR+ R + RR + + EKE +
Sbjct: 296 ----RPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKE 351
Query: 314 RKRKQEEQMETE 325
R+R++ ++ E E
Sbjct: 352 RRRERADRGEAE 363
Score = 65.9 bits (159), Expect = 5e-11
Identities = 68/238 (28%), Positives = 115/238 (48%), Gaps = 41/238 (17%)
Query: 88 PKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAA-- 145
P +K S + A K ASSD++ + SVS + ++ E +S + T D T K A
Sbjct: 160 PALKMSVSKRARK---ASSDLD----QASVSPSEEENSESSSESEKTSDQDFTPEKKAAV 212
Query: 146 ---RRG-----RKRKAEKQVETEE-----------------AGVVTTATASVNLKVS--- 177
RRG +K+KA +++ A +++++S + VS
Sbjct: 213 RAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKK 272
Query: 178 PKRGRPAATEVKIPKPRGR-PKMVKQPCPSESDIITEE-DK-SKKKGQEEKQPKKQPKKD 234
P RGR A E +PKPRGR PK + P S SD ++E D+ S+ K ++E + ++ +
Sbjct: 273 PPRGRKPA-EKPLPKPRGRKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARR 331
Query: 235 EEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGR 292
Q+EE + +E +K+E ++ E + A+ G +S E DD+ +K+ + GR
Sbjct: 332 RREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPVKKRGRKGR 389
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 203 bits (516), Expect = 2e-52
Identities = 128/372 (34%), Positives = 185/372 (49%), Gaps = 56/372 (15%)
Query: 1 MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP 60
M FKPGDL+FAKMKGYPHWPAR+D++ DGAVKPP NK PIFFFGTHETAFLGPKD+FP
Sbjct: 1 MPHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFP 60
Query: 61 YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKF------SSQQAATKQSNAS--SDVEVEE 112
Y + K+KYGKPNKRKGFNEGLWEI NNP + SS + ++N + SD + ++
Sbjct: 61 YDKCKDKYGKPNKRKGFNEGLWEIQNNPHASYSAPPPVSSSDSEAPEANPADGSDADEDD 120
Query: 113 KETSV--------------SKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAE-KQV 157
++ V + D+D ++ + N + + ++R RK ++ Q
Sbjct: 121 EDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQA 180
Query: 158 ETEEAGVVTTATASVNLKVSPKRGRP---AATEVKIPKPRGRPKMVKQPCPSESDIITEE 214
+ + ++S + K S + P AA P G K K P S+SD +
Sbjct: 181 SVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADS 240
Query: 215 D-------------KSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKR 261
D S KK G+K +KP +P ++ K E
Sbjct: 241 DGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPE----- 295
Query: 262 KNLAKTGVTSTSDSEEEGDDQEGEKKRKG---GRNFQTAHRRNMLK-----GQHEKEAAD 313
+ +S+SDS+ + D+ E KR+ R + RR + + EKE +
Sbjct: 296 ----RPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKE 351
Query: 314 RKRKQEEQMETE 325
R+R++ ++ E E
Sbjct: 352 RRRERADRGEAE 363
Score = 65.9 bits (159), Expect = 5e-11
Identities = 68/238 (28%), Positives = 115/238 (48%), Gaps = 41/238 (17%)
Query: 88 PKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAA-- 145
P +K S + A K ASSD++ + SVS + ++ E +S + T D T K A
Sbjct: 160 PALKMSVSKRARK---ASSDLD----QASVSPSEEENSESSSESEKTSDQDFTPEKKAAV 212
Query: 146 ---RRG-----RKRKAEKQVETEE-----------------AGVVTTATASVNLKVS--- 177
RRG +K+KA +++ A +++++S + VS
Sbjct: 213 RAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKK 272
Query: 178 PKRGRPAATEVKIPKPRGR-PKMVKQPCPSESDIITEE-DK-SKKKGQEEKQPKKQPKKD 234
P RGR A E +PKPRGR PK + P S SD ++E D+ S+ K ++E + ++ +
Sbjct: 273 PPRGRKPA-EKPLPKPRGRKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARR 331
Query: 235 EEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGR 292
Q+EE + +E +K+E ++ E + A+ G +S E DD+ +K+ + GR
Sbjct: 332 RREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPVKKRGRKGR 389
>gi|7705320 hepatoma-derived growth factor, related protein 3 [Homo
sapiens]
Length = 203
Score = 187 bits (476), Expect = 9e-48
Identities = 89/160 (55%), Positives = 116/160 (72%), Gaps = 7/160 (4%)
Query: 3 RDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYS 62
R++K GDL+FAKMKGYPHWPAR+DE+P+GAVKPP NK PIFFFGTHETAFLGPKD+FPY
Sbjct: 7 REYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYK 66
Query: 63 ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDT 122
E K+K+GK NKRKGFNEGLWEI+NNP VKF+ QA +QS++ ++ E + S+E+
Sbjct: 67 EYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEG 126
Query: 123 DHEE-----KASNEDV--TKAVDITTPKAARRGRKRKAEK 155
D E K NE + T+ K++++ RK ++
Sbjct: 127 DRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDE 166
Score = 29.6 bits (65), Expect = 3.9
Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 11/75 (14%)
Query: 207 ESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAK 266
E D + E+ K K+K ++ +K+ ++ K+ K + D K+ K+E E+K
Sbjct: 125 EGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEE-ENK------ 177
Query: 267 TGVTSTSDSEEEGDD 281
S+S+ + G+D
Sbjct: 178 ----SSSEGGDAGND 188
>gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]
Length = 240
Score = 185 bits (469), Expect = 6e-47
Identities = 112/265 (42%), Positives = 154/265 (58%), Gaps = 41/265 (15%)
Query: 3 RDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYS 62
+++K GDL+FAKMKGYPHWPAR+DE+P+ AVK NK +FFFGTHETAFLGPKD+FPY
Sbjct: 8 KEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYE 67
Query: 63 ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDT 122
E+KEK+GKPNKRKGF+EGLWEI+NNP VK S Q++ K+ S VE E E ++ D
Sbjct: 68 ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKK----SCVEEPEPEPEAAEGDG 123
Query: 123 D---HEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPK 179
D + E +S+E+ +D K K EK AG + L+ SPK
Sbjct: 124 DKKGNAEGSSDEEGKLVID--------EPAKEKNEKGALKRRAGDL--------LEDSPK 167
Query: 180 RGRPAATEVKIPKPRGRPK-----MVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKD 234
R + A P G K V++P P E E++ + + + P P+++
Sbjct: 168 RPKEA------ENPEGEEKEAATLEVERPLPME----VEKNSTPSEPGSGRGP---PQEE 214
Query: 235 EEGQKEEDKPRKEPDKKEGKKEVES 259
EE + EE++ KE + G ++ ES
Sbjct: 215 EEEEDEEEEATKEDAEAPGIRDHES 239
>gi|186928819 hepatoma-derived growth factor isoform b [Homo
sapiens]
Length = 256
Score = 145 bits (365), Expect = 6e-35
Identities = 96/246 (39%), Positives = 134/246 (54%), Gaps = 41/246 (16%)
Query: 22 PARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYGKPNKRKGFNEGL 81
P +DE+P+ AVK NK +FFFGTHETAFLGPKD+FPY E+KEK+GKPNKRKGF+EGL
Sbjct: 43 PHTIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL 102
Query: 82 WEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTD---HEEKASNEDVTKAVD 138
WEI+NNP VK S Q++ K+ S VE E E ++ D D + E +S+E+ +D
Sbjct: 103 WEIENNPTVKASGYQSSQKK----SCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVID 158
Query: 139 ITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPK 198
K K EK AG + L+ SPKR + A P G K
Sbjct: 159 --------EPAKEKNEKGALKRRAGDL--------LEDSPKRPKEA------ENPEGEEK 196
Query: 199 -----MVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEG 253
V++P P E E++ + + + P P+++EE + EE++ KE + G
Sbjct: 197 EAATLEVERPLPME----VEKNSTPSEPGSGRGP---PQEEEEEEDEEEEATKEDAEAPG 249
Query: 254 KKEVES 259
++ ES
Sbjct: 250 IRDHES 255
>gi|186928821 hepatoma-derived growth factor isoform c [Homo
sapiens]
Length = 233
Score = 144 bits (362), Expect = 1e-34
Identities = 96/245 (39%), Positives = 134/245 (54%), Gaps = 41/245 (16%)
Query: 23 ARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYGKPNKRKGFNEGLW 82
A +DE+P+ AVK NK +FFFGTHETAFLGPKD+FPY E+KEK+GKPNKRKGF+EGLW
Sbjct: 21 AVIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLW 80
Query: 83 EIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTD---HEEKASNEDVTKAVDI 139
EI+NNP VK S Q++ K+ S VE E E ++ D D + E +S+E+ +D
Sbjct: 81 EIENNPTVKASGYQSSQKK----SCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVID- 135
Query: 140 TTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPK- 198
K K EK AG + L+ SPKR + A P G K
Sbjct: 136 -------EPAKEKNEKGALKRRAGDL--------LEDSPKRPKEA------ENPEGEEKE 174
Query: 199 ----MVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGK 254
V++P P E E++ + + + P P+++EE + EE++ KE + G
Sbjct: 175 AATLEVERPLPME----VEKNSTPSEPGSGRGP---PQEEEEEEDEEEEATKEDAEAPGI 227
Query: 255 KEVES 259
++ ES
Sbjct: 228 RDHES 232
>gi|110681712 hepatoma derived growth factor-like 1 [Homo sapiens]
Length = 251
Score = 135 bits (340), Expect = 5e-32
Identities = 81/238 (34%), Positives = 118/238 (49%), Gaps = 27/238 (11%)
Query: 5 FKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSEN 64
+K GDL+FAK+KGY HWPAR++ + N+ +FFFGTHETAFL PK +FPY E
Sbjct: 9 YKSGDLVFAKLKGYAHWPARIEHMTQ------PNRYQVFFFGTHETAFLSPKRLFPYKEC 62
Query: 65 KEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDH 124
KEK+GKPNKR+GF+ GLWEI+NNP V+ S A+++ S D E E + ED
Sbjct: 63 KEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEK--GSGDGPWPEPEAAEGDEDKPT 120
Query: 125 EEKASNEDVTKAVDITTPKAARRGRKRKA------------------EKQVETEEAGVVT 166
+++ K D + + KR A E++ E E A
Sbjct: 121 HAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAE 180
Query: 167 TATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEE 224
A A+ + P V+ P +V +P E + + EE+ + ++ +E
Sbjct: 181 RAAAAAAATAVDEES-PFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQE 237
Score = 28.5 bits (62), Expect = 8.7
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Query: 220 KGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEG 279
+G E+K DE G+ ++DKP +E +K K+ ++ K + D EEE
Sbjct: 113 EGDEDKPTHAGGGGDELGKPDDDKPTEE-EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEA 171
Query: 280 D-DQEGEKKRKGGRNFQTA 297
+ ++ E +R TA
Sbjct: 172 EAERAAEAERAAAAAAATA 190
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 67.8 bits (164), Expect = 1e-11
Identities = 70/262 (26%), Positives = 112/262 (42%), Gaps = 25/262 (9%)
Query: 83 EIDNNPKVKFSSQQAATKQSNASSDVEVE----EKETSVSKEDTDHEEKASNEDVTKAVD 138
E + K K ++ A A S V+ E EK S KE+ EKA + + K +D
Sbjct: 701 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLD 760
Query: 139 ITTPKA-------ARRGRKRKAEKQVETEEAGVVTTATASVNLKV---SPKRGRPAATEV 188
+ +P+A AR + EK + V + A LK +P++ P EV
Sbjct: 761 VKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEV 820
Query: 189 KIP-KPRGRPKMVK---QPCPSESDII-----TEEDKSKKKGQEEKQPKKQPKKDEEGQK 239
K P K +P+ VK P +E + TEE K KK + K+ +PK +E+ +
Sbjct: 821 KSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP 880
Query: 240 EEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHR 299
+KP++ K E KKE +K + + + E + D + EK + A
Sbjct: 881 AVEKPKE--SKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKA 938
Query: 300 RNMLKGQHEKEAADRKRKQEEQ 321
+ K +KEAA K+ +E+
Sbjct: 939 KEPSKPAEKKEAAPEKKDTKEE 960
Score = 57.0 bits (136), Expect = 2e-08
Identities = 63/248 (25%), Positives = 97/248 (39%), Gaps = 23/248 (9%)
Query: 88 PKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARR 147
PK+ S K VE EKET + +E T EE E+VT+ + K A+
Sbjct: 427 PKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQT--EETQVTEEVTEEEE----KEAKE 480
Query: 148 GRKRKAEKQVETE-EAGVVTTATASVNLKVSPKRGR--PAATEVKIPKPRGRPKMVKQPC 204
++ E E E E G T + SP++ P E K P P+ +
Sbjct: 481 EEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKS 540
Query: 205 PSESDIITEEDKSKKKGQEE-------KQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEV 257
P+E + +K+K +EE K P+K+ K K +K K P K+E K
Sbjct: 541 PAE---VKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKA-KSPAKEEAKSPA 596
Query: 258 ESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRK 317
E+K AK+ V + S E E+ + ++ K E+ + K K
Sbjct: 597 EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTK---EEAKSPEKAK 653
Query: 318 QEEQMETE 325
E+ E +
Sbjct: 654 SPEKEEAK 661
Score = 55.1 bits (131), Expect = 9e-08
Identities = 60/237 (25%), Positives = 97/237 (40%), Gaps = 21/237 (8%)
Query: 63 ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDT 122
E KE+ GK + +G E E +++AA+ + A S V+ E K + +K
Sbjct: 477 EAKEEEGK--EEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPE 534
Query: 123 DHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGR 182
E K+ E + +P+ A+ K +A+ E + A + +K K
Sbjct: 535 KEEAKSPAE-------VKSPEKAKSPAKEEAKSPPEAKSPEK-EEAKSPAEVKSPEKAKS 586
Query: 183 PAATEVKIPKPRGRPKMVKQPCPSESDIITEED----KSKKKGQEEKQPKK--QPKKDEE 236
PA E K P P+ K P E+ E + K E K P+K P K+E
Sbjct: 587 PAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEA 646
Query: 237 GQKEEDK-PRKE----PDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKR 288
E+ K P KE P+K + + E+K AK+ V + + S E+ E+ +
Sbjct: 647 KSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK 703
Score = 53.9 bits (128), Expect = 2e-07
Identities = 61/281 (21%), Positives = 120/281 (42%), Gaps = 26/281 (9%)
Query: 65 KEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSN-----ASSDVEVEEKETSVSK 119
KE+ P K K + +P+ K +++ A ++ A S V+ E K +K
Sbjct: 741 KEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAK 800
Query: 120 EDTDHEEKASNEDVTKAVDITTP----KAARRGRKRKAEKQVETEEAGVVTTATASVNLK 175
+ KA +++ K ++ +P + + + ++ K+ E E+A AT K
Sbjct: 801 SPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA----PATPKTEEK 856
Query: 176 VSPKRGRPAATEVKIPKPRGRPKMVKQPC---PSESDIITE----EDKSKKKGQEEKQPK 228
K+ A + + PKP+ K K+P P ES + + EDK K E++ P
Sbjct: 857 KDSKKEE--APKKEAPKPKVEEK--KEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPA 912
Query: 229 K-QPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKK 287
K + K+D + +++ + +KEPD + K+ + K A T + + + +++ + +
Sbjct: 913 KVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTE 972
Query: 288 RKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEHQT 328
K + +T + K + EK Q++ E T
Sbjct: 973 AKAKEDDKTLSKEPS-KPKAEKAEKSSSTDQKDSKPPEKAT 1012
Score = 50.1 bits (118), Expect = 3e-06
Identities = 56/277 (20%), Positives = 116/277 (41%), Gaps = 13/277 (4%)
Query: 62 SENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKED 121
S KE+ P + K + + K ++ +++ + ++V+ EK S +KE+
Sbjct: 586 SPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEE 645
Query: 122 TDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLK---VSP 178
EKA + + +A K+ + + EK +A + A +K SP
Sbjct: 646 AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSP 705
Query: 179 KRGR-PAATEVKIPKPRGRPKMVKQPCPSES-DIITEEDKSKKKGQEEKQPK----KQPK 232
++ + P E K P+ P + P ++ + EE KS +K + ++ K K P+
Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPE 765
Query: 233 KDEEGQKEEDKPR-KEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKK---R 288
++E P K P+K + + E K AK+ + + + E+ ++ E K +
Sbjct: 766 AKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVK 825
Query: 289 KGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETE 325
+ + + + K + EK A K ++++ + E
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKE 862
Score = 50.1 bits (118), Expect = 3e-06
Identities = 45/221 (20%), Positives = 90/221 (40%), Gaps = 17/221 (7%)
Query: 73 KRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNED 132
K++ + E + +VK ++ A + + EEK+ S +E E +
Sbjct: 816 KKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVE 875
Query: 133 VTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPK 192
K + PK ++ K++ E E+ V T KV K + ++ K
Sbjct: 876 EKKEPAVEKPKESKVEAKKE-----EAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAK 930
Query: 193 PRGRPKMVKQPC-PSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKK 251
K+P P+E E K K+ ++ K+P+++PK + + ++++ KEP K
Sbjct: 931 KEPDDAKAKEPSKPAEKKEAAPEKKDTKE-EKAKKPEEKPKTEAKAKEDDKTLSKEPSKP 989
Query: 252 EGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGR 292
+ +K +S +ST + + ++ E K G+
Sbjct: 990 KAEKAEKS----------SSTDQKDSKPPEKATEDKAAKGK 1020
Score = 49.3 bits (116), Expect = 5e-06
Identities = 57/217 (26%), Positives = 90/217 (41%), Gaps = 21/217 (9%)
Query: 83 EIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASN---EDVTKAVDI 139
E+ + K K +++ A A S EKE + S + EKA + E+ +
Sbjct: 543 EVKSPEKAKSPAKEEAKSPPEAKSP----EKEEAKSPAEVKSPEKAKSPAKEEAKSPAEA 598
Query: 140 TTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKM 199
+P+ A+ K +A+ E + V A + +K K P E K P+ P+
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSP-VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEK 657
Query: 200 VKQPCPSESDI-ITEEDKSKKKGQEEKQP----KKQPKKDEEGQKEEDK---PRKEPDKK 251
+ P ++ + E KS +K K P K P+K + KEE K K P K+
Sbjct: 658 EEAKSPEKAKSPVKAEAKSPEKA---KSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714
Query: 252 EGK--KEVESKRKNLAKTGVTSTSDSEEEGDDQEGEK 286
E K ++ +S K AKT + S +EE E K
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAK 751
Score = 38.5 bits (88), Expect = 0.008
Identities = 26/119 (21%), Positives = 58/119 (48%), Gaps = 9/119 (7%)
Query: 163 GVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDI---ITEEDKSKK 219
G+ + S ++KV + ++K+ + + ++ + E+ + +TEE++ +
Sbjct: 425 GLPKIPSVSTHIKVKSEE------KIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEA 478
Query: 220 KGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEE 278
K +E K+ + +++ EG +EE K + +KE +S K AK+ + S +EE
Sbjct: 479 KEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEE 537
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 63.5 bits (153), Expect = 2e-10
Identities = 48/198 (24%), Positives = 91/198 (45%), Gaps = 11/198 (5%)
Query: 95 QQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAE 154
+Q KQ A S ++ + + E K +VTK + P + E
Sbjct: 531 KQTKLKQ-RADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPP-----KVESKE 584
Query: 155 KQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRG---RPKMVKQPCPSESDII 211
K + ++ + T SV K P + P+ + ++ + + +PK K+ + +
Sbjct: 585 KVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKV 644
Query: 212 TEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTS 271
EDK ++K + +K+ K K+D+ K+E+KP+KE KKE KKE++ + K K V
Sbjct: 645 KPEDKKEEKEKPKKEVAK--KEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKK 702
Query: 272 TSDSEEEGDDQEGEKKRK 289
+ +E + + E+K++
Sbjct: 703 ETPPKEVKKEVKKEEKKE 720
Score = 59.3 bits (142), Expect = 5e-09
Identities = 56/201 (27%), Positives = 89/201 (44%), Gaps = 27/201 (13%)
Query: 89 KVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRG 148
K + + +QA + A+ + V+ KET V ED E++ ++V K D T K +
Sbjct: 617 KAEVAEKQATDVKPKAAKEKTVK-KETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKP 675
Query: 149 RKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSES 208
+K + +K+V+ E K PK+ EVK P PK VK+
Sbjct: 676 KKEEVKKEVKKE---------IKKEEKKEPKK------EVKKETP---PKEVKK------ 711
Query: 209 DIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTG 268
++ EE K KK EEK+PKK+ KK + K+ P E K K K++ K
Sbjct: 712 EVKKEEKKEVKK--EEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKD 769
Query: 269 VTSTSDSEEEGDDQEGEKKRK 289
+ +E+G + +K+ K
Sbjct: 770 SVAAGKPKEKGKIKVIKKEGK 790
Score = 56.2 bits (134), Expect = 4e-08
Identities = 57/231 (24%), Positives = 99/231 (42%), Gaps = 16/231 (6%)
Query: 100 KQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVET 159
KQ A+ + T V K+ + S E + A K+ R+ + K E T
Sbjct: 512 KQPLATQKDLTGQVPTPVVKQTKLKQRADSRESLKPAAKPLPSKSVRK--ESKEETPEVT 569
Query: 160 EEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKS-K 218
+ V KV K+ +P TE K ++P P ++++ ++ K
Sbjct: 570 KVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVK 629
Query: 219 KKGQEEKQPKKQPK-KDEEGQKEEDKPRKEPDKKEGK---KEVESKRKNLAKTGVTSTSD 274
K +EK KK+ K K E+ ++E++KP+KE KKE K K+ E +K K V
Sbjct: 630 PKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIK 689
Query: 275 SEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETE 325
EE+ + ++ KK + +K + +KE +K+E++ + E
Sbjct: 690 KEEKKEPKKEVKKETPPKE---------VKKEVKKEEKKEVKKEEKEPKKE 731
Score = 53.9 bits (128), Expect = 2e-07
Identities = 48/191 (25%), Positives = 90/191 (47%), Gaps = 20/191 (10%)
Query: 99 TKQSNASSDVEVEEKETSVSKED----TDHEEKASNEDVTKAVDITTPKAARRGRKRKAE 154
TK ++ +VE KE + K+D T+ + + ++V + + KA AE
Sbjct: 569 TKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKA------EVAE 622
Query: 155 KQVETEEAGVVTTATASVNLKVSP--KRGRPAATEVKIPKPRGRPKMVKQPCPSESDIIT 212
KQ + T KV P K+ + ++ K + + K+ P + ++
Sbjct: 623 KQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKK 682
Query: 213 EEDKSKKKGQEEKQPKKQPKKD------EEGQKEEDKPRKEPDKKEGKKEVESKRKNLAK 266
E K KK +E+K+PKK+ KK+ ++ K+E+K + ++KE KKE++ K+ AK
Sbjct: 683 EVKKEIKK-EEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKD-AK 740
Query: 267 TGVTSTSDSEE 277
T S++++
Sbjct: 741 KSSTPLSEAKK 751
Score = 37.4 bits (85), Expect = 0.019
Identities = 59/273 (21%), Positives = 101/273 (36%), Gaps = 56/273 (20%)
Query: 55 PKDIFPYSENKEKYGKPNKRKGFNEGLWEIDNNPK-VKFSSQQAATKQSNASSDVEVEEK 113
PK++ + +K K +K E EI PK K SS + + A+ +V +K
Sbjct: 706 PKEV---KKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKK 762
Query: 114 ETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVN 173
E SV K+ + K +G+ + +K+ + EA T +
Sbjct: 763 EESVKKDS-----------------VAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATT 805
Query: 174 LKVSPKRGRPAATEVK--------IPKPRGRPKMVKQPCPSESDIITE--------EDKS 217
V G A K + P K ++ E D+ + ED+
Sbjct: 806 AAVMAAAGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDEE 865
Query: 218 KKKG---------QEEKQPKKQPKK---------DEEGQKEEDKPRKEPDKKEGKKEVES 259
K K Q+E++ K P + + EG+ E+ EP +K+G ++E
Sbjct: 866 KLKETEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEK 925
Query: 260 KRKNLAKTGVTS-TSDSEEEGDDQEGEKKRKGG 291
A +S T D EE+ + +E E+ + G
Sbjct: 926 FEDEGAGFEESSETGDYEEKAETEEAEEPEEDG 958
Score = 31.6 bits (70), Expect = 1.0
Identities = 59/278 (21%), Positives = 102/278 (36%), Gaps = 46/278 (16%)
Query: 61 YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETS---V 117
Y KE+ + +EG+ + + + + ++ + D+E E E +
Sbjct: 876 YVIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEE 935
Query: 118 SKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVS 177
S E D+EEKA E+ AE+ E E V +A+ K S
Sbjct: 936 SSETGDYEEKAETEE--------------------AEEPEEDGEEHVCVSAS-----KHS 970
Query: 178 PKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSK--KKGQEEKQPKKQPKKDE 235
P +A R + + V + D EED + +KG+ E+ ++ ++D+
Sbjct: 971 PTEDEESAKAEADAYIREKRESV-----ASGDDRAEEDMDEAIEKGEAEQSEEEADEEDK 1025
Query: 236 EGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKG----G 291
E++ EP+K E + V + A+ G +EE+ K+ G G
Sbjct: 1026 AEDAREEE--YEPEKMEAEDYVMAVVDKAAEAG-----GAEEQYGFLTTPTKQLGAQSPG 1078
Query: 292 RNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEHQTT 329
R ++ L G E EA + E E T
Sbjct: 1079 REPASSIHDETLPGGSESEATASDEENREDQPEEFTAT 1116
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 63.2 bits (152), Expect = 3e-10
Identities = 57/222 (25%), Positives = 103/222 (46%), Gaps = 38/222 (17%)
Query: 109 EVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTA 168
E+ E+E + +T E K E K K R KRK E++ E +
Sbjct: 37 EIREREREI---ETRKEGKKERESERK-------KERREREKRKREREKERKR------- 79
Query: 169 TASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEK-QP 227
+RG+ + + R R K ++ E + E++K KKK ++E+ +
Sbjct: 80 ----------ERGKKEKKGERKKEERERKKRRREKENKEGE---EKEKRKKKEKKERGRT 126
Query: 228 KKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKK 287
K+ K+ E ++ + + RKE ++K+ ++E E +RK K + EEE ++E +++
Sbjct: 127 SKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKER 186
Query: 288 RKGGRNFQTAHRRNMLKGQHEKEAADRK--RKQEEQMETEHQ 327
+K RN R+ K + KE +RK RK++E+ + E Q
Sbjct: 187 KKRERN-----RKERKKERERKERRERKKERKKKEERKKERQ 223
Score = 55.8 bits (133), Expect = 5e-08
Identities = 51/227 (22%), Positives = 95/227 (41%), Gaps = 18/227 (7%)
Query: 101 QSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETE 160
Q S++ E+E KE E ++ + R RKR+ EK+ + E
Sbjct: 31 QPGWQSEIREREREIETRKEGKKERESERKKE----------RREREKRKREREKERKRE 80
Query: 161 EAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKK 220
+ KR R + K + + K K+ + + E K ++K
Sbjct: 81 RGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERK 140
Query: 221 GQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKE-GKKEVESKRKNLAKTGVTSTSDSE--- 276
+E K+ ++ KK+E ++ E K RK+ ++K+ G+KE E K K + + E
Sbjct: 141 REERKE--RERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKK 198
Query: 277 --EEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQ 321
E + +E +K+RK + +++ EKE R+RK+ ++
Sbjct: 199 ERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 52.8 bits (125), Expect = 4e-07
Identities = 33/139 (23%), Positives = 71/139 (51%), Gaps = 12/139 (8%)
Query: 190 IPKPRGRPKMVKQPCPSESDIIT-EEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEP 248
I KP +P + E +I T +E K +++ + +K+ +++ K+ E +KE + R +
Sbjct: 25 ISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKK 84
Query: 249 DKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHE 308
+KK +K+ E +RK + E +++EGE+K K + + R +G+
Sbjct: 85 EKKGERKKEERERKKRRR-----------EKENKEGEEKEKRKKKEKKERGRTSKEGKER 133
Query: 309 KEAADRKRKQEEQMETEHQ 327
+ +RKR++ ++ E + +
Sbjct: 134 ERKEERKREERKERERKKE 152
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 62.4 bits (150), Expect = 5e-10
Identities = 77/303 (25%), Positives = 134/303 (44%), Gaps = 40/303 (13%)
Query: 63 ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQ-SNASSDVEVEEKETSVSKED 121
E KE+ G+ + +G E E D K + + + K+ S+ + E EE ET E
Sbjct: 519 EVKEEEGEKEEEEGQEEEEEE-DEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEG 577
Query: 122 TDHEEKASNEDVTKAVDITTPKA----ARRGRKRKAEKQVE---TEEAGVVTTATASVNL 174
+ E K + K+ ++ T + A+ + KA+ V EE G + V
Sbjct: 578 EEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEE 637
Query: 175 K-VSPKRGRPAATEVKIPKPRGR--------------PKMVKQPCPS----ESDIITEED 215
K SP P + K P P+ + K P P E+ E
Sbjct: 638 KGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVG 697
Query: 216 KSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEG----KKEVESKRKNLAKT-GVT 270
K ++K +EEK+ K+ PK +E+ +K+E+KP+ P+KK+ K+E ++ + K+ V
Sbjct: 698 KGEQKEEEEKEVKEAPK-EEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVH 756
Query: 271 STSDSEEEGD--DQEGEKKRKGGRNFQTAHRRNM-LKGQHEKEAA---DRKRKQEEQMET 324
+++EEG QE EK++ GG + KG +++ A + + K+E + ET
Sbjct: 757 LEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQET 816
Query: 325 EHQ 327
+ +
Sbjct: 817 KEK 819
Score = 51.6 bits (122), Expect = 1e-06
Identities = 60/256 (23%), Positives = 113/256 (44%), Gaps = 13/256 (5%)
Query: 79 EGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDV--TKA 136
E E + P+ + + AA K ++ EV+E+E +E+ EE+ +E +A
Sbjct: 490 EAAEEKEEEPEAE-EEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA 548
Query: 137 VDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPR-G 195
+ + K ++ +++ ETE A A KV K A E + +
Sbjct: 549 EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVE 608
Query: 196 RPKMVKQPCPSESDIITEEDKS--KKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEG 253
+P+ K P P + E+ KS K EEK PK E + + P K P +++G
Sbjct: 609 KPEKAKSPVPKSP--VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP-KSPVEEKG 665
Query: 254 KKEV-ESKRKNLAKTGV--TSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEK- 309
K V +S + AK+ V + +++ + + +GE+K + + + A + ++ + EK
Sbjct: 666 KSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKP 725
Query: 310 EAADRKRKQEEQMETE 325
+ K+K E ++ E
Sbjct: 726 KDVPEKKKAESPVKEE 741
Score = 46.2 bits (108), Expect = 4e-05
Identities = 37/140 (26%), Positives = 71/140 (50%), Gaps = 15/140 (10%)
Query: 154 EKQVETEEAGVVTTATA-SVNLKVSPKRGRPAATEVKIPKPRGRPKMV---KQPCPSESD 209
E +VE E++ + TA + L VS K + A E K +P + V K P + +
Sbjct: 459 ETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAP 518
Query: 210 IITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGV 269
+ EE+ K EE++ +++ ++++EG K D+ + +KEG E E + +T
Sbjct: 519 EVKEEEGEK----EEEEGQEEEEEEDEGAKS-DQAEEGGSEKEGSSEKEEGEQEEGET-- 571
Query: 270 TSTSDSEEEGDDQEGEKKRK 289
++E EG++ E ++++K
Sbjct: 572 ----EAEAEGEEAEAKEEKK 587
Score = 44.7 bits (104), Expect = 1e-04
Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 1/144 (0%)
Query: 183 PAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEED 242
P KI KP+ +K +II E +K + E+ ++ KEE
Sbjct: 429 PITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEK 488
Query: 243 KPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNM 302
K E ++E + E E + T+ EEEG+ +E E + + + A
Sbjct: 489 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA 548
Query: 303 LKGQHEKEAADRKRK-QEEQMETE 325
+G EKE + K + ++E+ ETE
Sbjct: 549 EEGGSEKEGSSEKEEGEQEEGETE 572
Score = 42.4 bits (98), Expect = 6e-04
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 14/158 (8%)
Query: 174 LKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKK 233
LKV K E K+ + + E + +E+K K+ EEK+ + + ++
Sbjct: 446 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEK--KEAAEEKEEEPEAEE 503
Query: 234 DEEGQKEEDKPRKEPDKKE--GKKEVESKRKNLAKTGVTSTSDSEEE-GDDQEGEKKRKG 290
+E K+ P+ KE G+KE E ++ + + SD EE G ++EG +++
Sbjct: 504 EEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEE 563
Query: 291 GRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEHQT 328
G + G+ E EA + + +E+ + E ++
Sbjct: 564 GEQEE---------GETEAEAEGEEAEAKEEKKVEEKS 592
Score = 40.8 bits (94), Expect = 0.002
Identities = 44/183 (24%), Positives = 73/183 (39%), Gaps = 12/183 (6%)
Query: 90 VKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKA--VDITTPKAARR 147
V S + K S VE + + V K + EE+ ++ K V+ K
Sbjct: 669 VSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDV 728
Query: 148 GRKRKAEKQVETEEAGVVTTATASVNL---KVSPKRGRPAATEVKIPKPRGRPKMVKQPC 204
K+KAE V+ E V T T SV + K + + G+P E + K G ++
Sbjct: 729 PEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGS 788
Query: 205 PSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDK-------PRKEPDKKEGKKEV 257
+ +ED + E K+ +Q K++ +EE+K D+K+G +
Sbjct: 789 DKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKS 848
Query: 258 ESK 260
E K
Sbjct: 849 EEK 851
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 62.4 bits (150), Expect = 5e-10
Identities = 77/303 (25%), Positives = 134/303 (44%), Gaps = 40/303 (13%)
Query: 63 ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQ-SNASSDVEVEEKETSVSKED 121
E KE+ G+ + +G E E D K + + + K+ S+ + E EE ET E
Sbjct: 143 EVKEEEGEKEEEEGQEEEEEE-DEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEG 201
Query: 122 TDHEEKASNEDVTKAVDITTPKA----ARRGRKRKAEKQVE---TEEAGVVTTATASVNL 174
+ E K + K+ ++ T + A+ + KA+ V EE G + V
Sbjct: 202 EEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEE 261
Query: 175 K-VSPKRGRPAATEVKIPKPRGR--------------PKMVKQPCPS----ESDIITEED 215
K SP P + K P P+ + K P P E+ E
Sbjct: 262 KGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVG 321
Query: 216 KSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEG----KKEVESKRKNLAKT-GVT 270
K ++K +EEK+ K+ PK +E+ +K+E+KP+ P+KK+ K+E ++ + K+ V
Sbjct: 322 KGEQKEEEEKEVKEAPK-EEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVH 380
Query: 271 STSDSEEEGD--DQEGEKKRKGGRNFQTAHRRNM-LKGQHEKEAA---DRKRKQEEQMET 324
+++EEG QE EK++ GG + KG +++ A + + K+E + ET
Sbjct: 381 LEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQET 440
Query: 325 EHQ 327
+ +
Sbjct: 441 KEK 443
Score = 51.6 bits (122), Expect = 1e-06
Identities = 60/256 (23%), Positives = 113/256 (44%), Gaps = 13/256 (5%)
Query: 79 EGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDV--TKA 136
E E + P+ + + AA K ++ EV+E+E +E+ EE+ +E +A
Sbjct: 114 EAAEEKEEEPEAE-EEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA 172
Query: 137 VDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPR-G 195
+ + K ++ +++ ETE A A KV K A E + +
Sbjct: 173 EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVE 232
Query: 196 RPKMVKQPCPSESDIITEEDKS--KKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEG 253
+P+ K P P + E+ KS K EEK PK E + + P K P +++G
Sbjct: 233 KPEKAKSPVPKSP--VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP-KSPVEEKG 289
Query: 254 KKEV-ESKRKNLAKTGV--TSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEK- 309
K V +S + AK+ V + +++ + + +GE+K + + + A + ++ + EK
Sbjct: 290 KSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKP 349
Query: 310 EAADRKRKQEEQMETE 325
+ K+K E ++ E
Sbjct: 350 KDVPEKKKAESPVKEE 365
Score = 46.2 bits (108), Expect = 4e-05
Identities = 37/140 (26%), Positives = 71/140 (50%), Gaps = 15/140 (10%)
Query: 154 EKQVETEEAGVVTTATA-SVNLKVSPKRGRPAATEVKIPKPRGRPKMV---KQPCPSESD 209
E +VE E++ + TA + L VS K + A E K +P + V K P + +
Sbjct: 83 ETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAP 142
Query: 210 IITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGV 269
+ EE+ K EE++ +++ ++++EG K D+ + +KEG E E + +T
Sbjct: 143 EVKEEEGEK----EEEEGQEEEEEEDEGAKS-DQAEEGGSEKEGSSEKEEGEQEEGET-- 195
Query: 270 TSTSDSEEEGDDQEGEKKRK 289
++E EG++ E ++++K
Sbjct: 196 ----EAEAEGEEAEAKEEKK 211
Score = 44.7 bits (104), Expect = 1e-04
Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 1/144 (0%)
Query: 183 PAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEED 242
P KI KP+ +K +II E +K + E+ ++ KEE
Sbjct: 53 PITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEK 112
Query: 243 KPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNM 302
K E ++E + E E + T+ EEEG+ +E E + + + A
Sbjct: 113 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA 172
Query: 303 LKGQHEKEAADRKRK-QEEQMETE 325
+G EKE + K + ++E+ ETE
Sbjct: 173 EEGGSEKEGSSEKEEGEQEEGETE 196
Score = 42.4 bits (98), Expect = 6e-04
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 14/158 (8%)
Query: 174 LKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKK 233
LKV K E K+ + + E + +E+K K+ EEK+ + + ++
Sbjct: 70 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEK--KEAAEEKEEEPEAEE 127
Query: 234 DEEGQKEEDKPRKEPDKKE--GKKEVESKRKNLAKTGVTSTSDSEEE-GDDQEGEKKRKG 290
+E K+ P+ KE G+KE E ++ + + SD EE G ++EG +++
Sbjct: 128 EEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEE 187
Query: 291 GRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEHQT 328
G + G+ E EA + + +E+ + E ++
Sbjct: 188 GEQEE---------GETEAEAEGEEAEAKEEKKVEEKS 216
Score = 40.8 bits (94), Expect = 0.002
Identities = 44/183 (24%), Positives = 73/183 (39%), Gaps = 12/183 (6%)
Query: 90 VKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKA--VDITTPKAARR 147
V S + K S VE + + V K + EE+ ++ K V+ K
Sbjct: 293 VSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDV 352
Query: 148 GRKRKAEKQVETEEAGVVTTATASVNL---KVSPKRGRPAATEVKIPKPRGRPKMVKQPC 204
K+KAE V+ E V T T SV + K + + G+P E + K G ++
Sbjct: 353 PEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGS 412
Query: 205 PSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDK-------PRKEPDKKEGKKEV 257
+ +ED + E K+ +Q K++ +EE+K D+K+G +
Sbjct: 413 DKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKS 472
Query: 258 ESK 260
E K
Sbjct: 473 EEK 475
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 61.6 bits (148), Expect = 9e-10
Identities = 58/233 (24%), Positives = 104/233 (44%), Gaps = 24/233 (10%)
Query: 93 SSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRK 152
S + K S D+E ++E +K+D+ K +D K D T +G +K
Sbjct: 132 SELKQGKKDSKKGKDIEKGKEEKLDAKKDS----KKGKKDAEKGKDSATESEDEKGGAKK 187
Query: 153 AEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIIT 212
K+ + + +AT S K ++ + + K +G+ ++ ++D
Sbjct: 188 DNKKDKKDSNKGKDSATESEGEKGGTEKD---SKKGKKDSKKGKDSAIELQAV-KADEKK 243
Query: 213 EED--KSKKKGQEEKQPKKQPKKDEEGQKEEDKP------RKEPDKKEGKKEVESKRKNL 264
+ED K KG E K KK K+ ++G+K++ KP K+ KKE KK+ K +
Sbjct: 244 DEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKV 303
Query: 265 AKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRK 317
AK D+E+E D + + K+ ++ + ++N K EK+ A +K K
Sbjct: 304 AK------KDTEKESADSKKDAKKNAKKDAKKDAKKNAKK--DEKKDAKKKGK 348
Score = 61.2 bits (147), Expect = 1e-09
Identities = 64/266 (24%), Positives = 116/266 (43%), Gaps = 41/266 (15%)
Query: 81 LWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDIT 140
L I P V ++++ K + VEV+ K + K+ E+K + +D T +
Sbjct: 81 LMRISERPSVYLAARRQPLKPTRT---VEVDSKAAEIGKKG---EDKTTQKDTTDS---- 130
Query: 141 TPKAARRGRK-RKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRP-- 197
++G+K K K +E + + S K ++G+ +ATE + K +
Sbjct: 131 -ESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDN 189
Query: 198 KMVKQPCPSESDIITEED--------------KSKKKGQ----EEKQPKKQPKKDEEGQK 239
K K+ D TE + K KKG+ E + K KKDE+G+K
Sbjct: 190 KKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKK 249
Query: 240 EEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHR 299
+ +K + D K+ KE++ +K+ K S++DS+ + D ++ KK T
Sbjct: 250 DANKGDESKDAKKDAKEIKKGKKDKKK---PSSTDSDSKDDVKKESKKD------ATKDA 300
Query: 300 RNMLKGQHEKEAADRKRKQEEQMETE 325
+ + K EKE+AD K+ ++ + +
Sbjct: 301 KKVAKKDTEKESADSKKDAKKNAKKD 326
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 61.6 bits (148), Expect = 9e-10
Identities = 50/239 (20%), Positives = 102/239 (42%), Gaps = 15/239 (6%)
Query: 95 QQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAE 154
Q+ ++ N E E + +K + H E+ + + + T + + R+R +
Sbjct: 176 QKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQ 235
Query: 155 KQVETEEAGVVTTATASVNLKVSPK-----RGRPAATEVKIPKPRGRPKMVKQPCPSESD 209
++ E E AS K R R + + K R R K+ +E D
Sbjct: 236 RKTEREREKQAERERASERETERDKERERERDRDRDRDRR-QKERERQTDRKRQRRTERD 294
Query: 210 IITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGV 269
TE + +++ + E++ ++ K++ E ++E ++ R+ +++ +KE E KRK
Sbjct: 295 RETERKRERQR-ERERERERNRKRERERERERERERQRETERDREKERERKRKR------ 347
Query: 270 TSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEHQT 328
++ + E + Q G + R+ + R + E+E +R R ++ Q E E QT
Sbjct: 348 --QTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQT 404
Score = 57.4 bits (137), Expect = 2e-08
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 13/220 (5%)
Query: 111 EEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATA 170
+E+E +E EK N K + T + RGR R+ + Q E E A
Sbjct: 103 KERERQTDRERDRQREKERNRQ--KERERETEREGERGRDRQTDGQRERERQ-----RDA 155
Query: 171 SVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITE---EDKSKKKGQEEKQP 227
+ R R TE K R R K ++ E E ED+ ++G+E ++
Sbjct: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER- 214
Query: 228 KKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKK 287
+++ + + E +++ D+ R K E ++E +++R+ ++ + E E D +
Sbjct: 215 ERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDR 274
Query: 288 RKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEHQ 327
R+ R QT +R + + ++E +RKR+++ + E E +
Sbjct: 275 RQKERERQTDRKRQR-RTERDRET-ERKRERQRERERERE 312
Score = 57.0 bits (136), Expect = 2e-08
Identities = 51/232 (21%), Positives = 105/232 (45%), Gaps = 52/232 (22%)
Query: 94 SQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKA 153
+++ +Q++ + E + + + +E+ E + + T + + RGR+R+
Sbjct: 155 AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER 214
Query: 154 EKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITE 213
E++ ETE TE K R R + K TE
Sbjct: 215 ERETETE-------------------------TERKRQTDRERDRQRK----------TE 239
Query: 214 EDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTS 273
++ +K+ + E+ +++ ++D+E ++E D+ R + D+++ ++E ++ RK +T
Sbjct: 240 RER-EKQAERERASERETERDKERERERDRDR-DRDRRQKERERQTDRKRQRRT------ 291
Query: 274 DSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETE 325
D+E E+KR+ R + RN K + E+E R+R++E Q ETE
Sbjct: 292 -----ERDRETERKRERQRERERERERNR-KRERERE---RERERERQRETE 334
Score = 52.0 bits (123), Expect = 7e-07
Identities = 45/239 (18%), Positives = 101/239 (42%), Gaps = 12/239 (5%)
Query: 83 EIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTP 142
E D K + ++ A ++ +S+ E E + + D D + ++ + D
Sbjct: 231 ERDRQRKTEREREKQAERER--ASERETERDKERERERDRDRDRDRRQKERERQTDRKRQ 288
Query: 143 KAARRGRK--RKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMV 200
+ R R+ RK E+Q E E N K +R R E + R R K
Sbjct: 289 RRTERDRETERKRERQRERERE-------RERNRKRERERERERERERQRETERDREKER 341
Query: 201 KQPCPSESDIITEEDKSK-KKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVES 259
++ ++++ E ++ ++G+ + + +++ +++ + Q ++ +E D+ +++
Sbjct: 342 ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERE 401
Query: 260 KRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQ 318
++ + G T E D+E E+ R+ GR + R + + A R+RK+
Sbjct: 402 RQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 50.1 bits (118), Expect = 3e-06
Identities = 47/270 (17%), Positives = 116/270 (42%), Gaps = 38/270 (14%)
Query: 73 KRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTD-----HEEK 127
+R+G + + D + + + ++ ++ ++ E + K ++D H E+
Sbjct: 38 RRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRER 97
Query: 128 ASNEDVTKA--VDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAA 185
+ + + D + + R R+ E++ ETE G +RGR
Sbjct: 98 QRDREKERERQTDRERDRQREKERNRQKERERETEREG---------------ERGRDRQ 142
Query: 186 TEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPR 245
T+ + + R R ++ ++ + + +++++K + E++ +Q +++ E Q+E++
Sbjct: 143 TDGQRERERQRDAEKERERQTDRERQRQTERNRQK-EREREKNRQERRERERQREKENKT 201
Query: 246 KEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKG 305
++ + G+ E E +R+ T T + D+E +++RK R + R
Sbjct: 202 EDRHSERGR-ERERERE-------TETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Query: 306 QHEKEAADRKRKQE-------EQMETEHQT 328
+ + +R+R+++ Q E E QT
Sbjct: 254 RETERDKERERERDRDRDRDRRQKERERQT 283
Score = 47.4 bits (111), Expect = 2e-05
Identities = 45/189 (23%), Positives = 93/189 (49%), Gaps = 25/189 (13%)
Query: 155 KQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEE 214
K++ A + T V + + R RP + E P+ RG + K ++ D +
Sbjct: 3 KKIVPATADQLGTLWVEVTIPLDFSRRRPGSQES--PRRRGLGQAHKD---ADGD---DR 54
Query: 215 DKSKKKGQEEKQPKKQPKKD----EEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVT 270
+++++K +E ++ K+Q +++ E ++E+D+ RK +E +++ E +R+ +T
Sbjct: 55 ERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERER--QTDRE 112
Query: 271 STSDSEEEGD---DQEGEKKRKGGRNFQTAHRRNMLKGQHEKEA---ADRKRKQEEQMET 324
E+E + ++E E +R+G R R GQ E+E A+++R+++ E
Sbjct: 113 RDRQREKERNRQKERERETEREGERG-----RDRQTDGQRERERQRDAEKERERQTDRER 167
Query: 325 EHQTTCNLQ 333
+ QT N Q
Sbjct: 168 QRQTERNRQ 176
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 61.2 bits (147), Expect = 1e-09
Identities = 57/270 (21%), Positives = 113/270 (41%), Gaps = 35/270 (12%)
Query: 54 GPKDIFPYSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEK 113
G K++ E K++ G+ ++K +G + + N +++ ++ + D E EE+
Sbjct: 692 GEKELAEKEEWKKRDGEEQEQKEREQG-HQKERNQEMEEGGEEEHGEGEEEEGDREEEEE 750
Query: 114 ETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVN 173
+ KE+ + EE + + +RK E++ EE G
Sbjct: 751 KEGEGKEEGEGEEVEGEREKEEG-------------ERKKEERAGKEEKG---------- 787
Query: 174 LKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKK 233
+ G E + + RG K E + + + KG+ E++ ++ +
Sbjct: 788 ----EEEGDQGEGEEEETEGRGEEK-------EEGGEVEGGEVEEGKGEREEEEEEGEGE 836
Query: 234 DEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRN 293
+EEG+ EE++ E ++ EGK E E + + G + EEE + EGE++ +G
Sbjct: 837 EEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGE 896
Query: 294 FQTAHRRNMLKGQHEKEAADRKRKQEEQME 323
+ +G+ E E + + K EE+ E
Sbjct: 897 EEEGEGEGEEEGEGEGEEEEGEGKGEEEGE 926
Score = 52.4 bits (124), Expect = 6e-07
Identities = 79/305 (25%), Positives = 128/305 (41%), Gaps = 73/305 (23%)
Query: 47 THETAFLGPKDIFPYSENKE-KYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNAS 105
T +TA D Y E E K GK K+ ++G+ F +Q A T ++ +
Sbjct: 533 TQDTALTENDDSDEYEEMSEMKEGKACKQH-VSQGI----------FMTQPATTIEAFSD 581
Query: 106 SDVEV-EEKETSVSKEDTDHEEKA--SNEDVTKAVDITTPKAARRGRKRKAEKQVE--TE 160
+VE+ EEKE + + EE+ +NE+ K GRK K E + T+
Sbjct: 582 EEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKV---------HGGRKEKTEILSDDLTD 632
Query: 161 EAGVVTTATASVNLKVSPKRGRPAAT---------------EVKIPKPRGRPKMVKQPCP 205
+A V SV GR T K K +GR +M ++P
Sbjct: 633 KAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEM-ERPGE 691
Query: 206 SESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLA 265
E ++ +E+ K+ G+E++Q K+ E+G ++E E +E E E
Sbjct: 692 GEKELAEKEEWKKRDGEEQEQ-----KEREQGHQKERNQEMEEGGEEEHGEGE------- 739
Query: 266 KTGVTSTSDSEEEGD-DQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQ----EE 320
EEEGD ++E EK+ +G + ++G+ EKE +RK+++ EE
Sbjct: 740 ----------EEEGDREEEEEKEGEGKEEGEGEE----VEGEREKEEGERKKEERAGKEE 785
Query: 321 QMETE 325
+ E E
Sbjct: 786 KGEEE 790
Score = 45.1 bits (105), Expect = 9e-05
Identities = 32/115 (27%), Positives = 62/115 (53%), Gaps = 16/115 (13%)
Query: 213 EEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTST 272
EE++ + +G+EE+ + + +EEG+ EE+ + +++EG+ E E + G
Sbjct: 982 EEEEGEGEGEEEEG---EEEGEEEGEGEEEGEGEGEEEEEGEVEGEVE-------GEEGE 1031
Query: 273 SDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEHQ 327
+ EEE ++EGE++ K G + +RRN + E+E + K ++ + E E Q
Sbjct: 1032 GEGEEEEGEEEGEEREKEGEGEE--NRRN----REEEEEEEGKYQETGEEENERQ 1080
Score = 43.1 bits (100), Expect = 3e-04
Identities = 29/120 (24%), Positives = 61/120 (50%), Gaps = 9/120 (7%)
Query: 213 EEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTST 272
EE+ + +G+ E++ + +D EG+ EE++ E +++EG+ E E + + + G
Sbjct: 922 EEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEG 981
Query: 273 SDSEEEGD------DQEGEKKRKG---GRNFQTAHRRNMLKGQHEKEAADRKRKQEEQME 323
+ E EG+ ++EGE++ +G G ++G+ E E + + ++EE E
Sbjct: 982 EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEE 1041
Score = 41.6 bits (96), Expect = 0.001
Identities = 28/110 (25%), Positives = 54/110 (49%), Gaps = 6/110 (5%)
Query: 213 EEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLA--KTGVT 270
EE++ + KG+EE + + ++EEG+ E + E +++EG+ E E + + G
Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEG 972
Query: 271 STSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEE 320
+ E EG+++EGE G + +G+ E+E ++EE
Sbjct: 973 EGEEGEGEGEEEEGE----GEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018
Score = 40.8 bits (94), Expect = 0.002
Identities = 30/121 (24%), Positives = 61/121 (50%), Gaps = 10/121 (8%)
Query: 213 EEDKSKKKGQEEKQPKKQPKKDEEGQKE-EDKPRKEPDKKEGKKEVESKRKNLAKTGVTS 271
EE++ + +G+EE + + + + E ++E E + +E ++EG++E E + +
Sbjct: 958 EEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEG------EG 1011
Query: 272 TSDSEEEGD---DQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEHQT 328
+ EEEG+ + EGE+ G + + + E E R R++EE+ E ++Q
Sbjct: 1012 EGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQE 1071
Query: 329 T 329
T
Sbjct: 1072 T 1072
Score = 39.3 bits (90), Expect = 0.005
Identities = 27/113 (23%), Positives = 57/113 (50%), Gaps = 10/113 (8%)
Query: 214 EDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTS 273
E++ + +G+EE+ K ++ EEG+ E ++ E + ++G+ E E +
Sbjct: 905 EEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEE---------GEW 955
Query: 274 DSEEEGDDQEGEKKRKG-GRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETE 325
+ EEE + EGE++ +G G + +G+ E+E + + ++E + E E
Sbjct: 956 EGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEE 1008
Score = 39.3 bits (90), Expect = 0.005
Identities = 21/77 (27%), Positives = 44/77 (57%), Gaps = 4/77 (5%)
Query: 213 EEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTST 272
EE++ + +G+ E + + ++EEG++E ++ KE + +E ++ E + + K T
Sbjct: 1015 EEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQET-- 1072
Query: 273 SDSEEEGDDQEGEKKRK 289
EEE + Q+GE+ +K
Sbjct: 1073 --GEEENERQDGEEYKK 1087
Score = 35.8 bits (81), Expect = 0.055
Identities = 23/88 (26%), Positives = 50/88 (56%), Gaps = 13/88 (14%)
Query: 214 EDKSKKKGQEEKQPKKQPK---KDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVT 270
E++ + +G+EE++ + + + ++ EG+ EE++ +E +++E + E E R+N +
Sbjct: 1006 EEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREE---- 1061
Query: 271 STSDSEEEGDDQ---EGEKKRKGGRNFQ 295
+ EEEG Q E E +R+ G ++
Sbjct: 1062 ---EEEEEGKYQETGEEENERQDGEEYK 1086
Score = 35.8 bits (81), Expect = 0.055
Identities = 19/76 (25%), Positives = 46/76 (60%), Gaps = 1/76 (1%)
Query: 213 EEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKP-RKEPDKKEGKKEVESKRKNLAKTGVTS 271
E ++ + +G+EE+ ++ ++++EG+ EE++ R+E +++EGK + + +N + G
Sbjct: 1026 EGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEY 1085
Query: 272 TSDSEEEGDDQEGEKK 287
S+ +G + G+ K
Sbjct: 1086 KKVSKIKGSVKYGKHK 1101
Score = 34.3 bits (77), Expect = 0.16
Identities = 18/66 (27%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 213 EEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTST 272
EE++ ++ +EE++ K Q +EE ++++ + K+ K +G + K K K VT+T
Sbjct: 1053 EENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKY-GKHKTYQKKSVTNT 1111
Query: 273 SDSEEE 278
+ +E
Sbjct: 1112 QGNGKE 1117
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 59.7 bits (143), Expect = 4e-09
Identities = 33/111 (29%), Positives = 63/111 (56%), Gaps = 3/111 (2%)
Query: 212 TEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTS 271
TEE + ++ +E++ +K+ +K++ +KE+ K KE +K++ K+E E KRK K
Sbjct: 13 TEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEE 72
Query: 272 ---TSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQE 319
+ EEE +++E E+K +G R + RR + + +K+ RK K++
Sbjct: 73 EEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 54.7 bits (130), Expect = 1e-07
Identities = 31/100 (31%), Positives = 53/100 (53%), Gaps = 10/100 (10%)
Query: 228 KKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKK 287
KK+ KK E + EE + +E ++KEGK++ + K K K T ++E+ + +E EKK
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 288 RKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEHQ 327
RK R K + E+E + + ++EE+ E E +
Sbjct: 62 RK----------RKRKKKKEEEEREEEEEEEEEEKEEEEK 91
Score = 51.6 bits (122), Expect = 1e-06
Identities = 25/109 (22%), Positives = 60/109 (55%)
Query: 219 KKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEE 278
KK +++K+ ++ ++ EE ++EE+K K +K++ K++ + K+K +T + EE+
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 279 GDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEHQ 327
++ +KK++ + K + EKE R++K++++ E +
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEE 109
Score = 49.3 bits (116), Expect = 5e-06
Identities = 32/123 (26%), Positives = 65/123 (52%), Gaps = 15/123 (12%)
Query: 213 EEDKSKKKGQEEKQPKKQPKKDEE--GQKEEDKP--RKEPDKKEGKKEVES--------- 259
++ K KKK EE + ++ +++EE G+++E + RKE +KK+ KE E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 260 --KRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRK 317
KRK K + EEE ++++ E++++ GR + +R + + EK+ R++
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120
Query: 318 QEE 320
+++
Sbjct: 121 KKK 123
Score = 46.6 bits (109), Expect = 3e-05
Identities = 36/141 (25%), Positives = 70/141 (49%), Gaps = 23/141 (16%)
Query: 149 RKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSES 208
+K+K +K ETEE T + K G+ + K + + K K+
Sbjct: 2 KKKKKKK--ETEE-----TEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKE------ 48
Query: 209 DIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTG 268
E + +K+ +E+K+ +K+ KK EE ++EE++ +E +K+E +KE +RK K
Sbjct: 49 ----TEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK-- 102
Query: 269 VTSTSDSEEEGDDQEGEKKRK 289
+EE ++++ +++RK
Sbjct: 103 ----RRRKEEEEEKKKKRRRK 119
Score = 45.4 bits (106), Expect = 7e-05
Identities = 31/115 (26%), Positives = 59/115 (51%), Gaps = 3/115 (2%)
Query: 150 KRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESD 209
K+K +K+ ETEE T T K ++ + + K + + K+ E +
Sbjct: 1 KKKKKKKKETEETEE-TEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59
Query: 210 IITEEDKSKKKGQEEKQPKKQPKKD--EEGQKEEDKPRKEPDKKEGKKEVESKRK 262
+ + KKK +EE++ +++ +++ EE +KEE + RK+ K+ K+E E K+K
Sbjct: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114
Score = 40.8 bits (94), Expect = 0.002
Identities = 33/141 (23%), Positives = 66/141 (46%), Gaps = 26/141 (18%)
Query: 111 EEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATA 170
+E E + E+T+ EE+ + K R+ ++++ EK+ +T+E
Sbjct: 8 KETEETEETEETEEEEEKEGK----------RKEKRKEKRKEKEKKKKTKE--------- 48
Query: 171 SVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITE-EDKSKKKGQEEKQPKK 229
+ KR E K + R + K ++ E + E E++ K++G+ K+ KK
Sbjct: 49 ------TEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK 102
Query: 230 QPKKDEEGQKEEDKPRKEPDK 250
+ +K+EE +K++ + RK K
Sbjct: 103 RRRKEEEEEKKKKRRRKTKKK 123
Score = 37.4 bits (85), Expect = 0.019
Identities = 33/150 (22%), Positives = 69/150 (46%), Gaps = 35/150 (23%)
Query: 111 EEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATA 170
E +ET ++E + EEK K R+ ++++ EK+ +T+E
Sbjct: 9 ETEETEETEETEEEEEKEGKR-----------KEKRKEKRKEKEKKKKTKE--------- 48
Query: 171 SVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQ 230
+ KR E K + R + K ++ E EE++ +K+ +E+++ +++
Sbjct: 49 ------TEKRKEKEEEEKKRKRKRKKKKEEEEREEEE-----EEEEEEKEEEEKEEGRRR 97
Query: 231 PKKDEEGQKEEDKPRKEPDKKEGKKEVESK 260
KK + +KEE+ E KK+ +++ + K
Sbjct: 98 KKKKKRRRKEEE----EEKKKKRRRKTKKK 123
Score = 32.7 bits (73), Expect = 0.46
Identities = 26/103 (25%), Positives = 46/103 (44%), Gaps = 17/103 (16%)
Query: 63 ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETS----VS 118
E +EK GK +++ K K ++ TK++ + E EEK+
Sbjct: 21 EEEEKEGKRKEKR-----------KEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKK 69
Query: 119 KEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEE 161
KE+ + EE+ E+ K + + RR +K+K ++ E EE
Sbjct: 70 KEEEEREEEEEEEEEEKEEE--EKEEGRRRKKKKKRRRKEEEE 110
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 59.3 bits (142), Expect = 5e-09
Identities = 57/268 (21%), Positives = 117/268 (43%), Gaps = 10/268 (3%)
Query: 63 ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAAT---KQSNASSDVEVEEKETSVSK 119
E +E+ + KR E E+ K S ++ K SS+ +E+E
Sbjct: 189 EKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGS 248
Query: 120 EDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAE--KQVETEEAGVVTTATASVN---L 174
++ H EK ED +A A + KAE K++ E A + A+
Sbjct: 249 DEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERER 308
Query: 175 KVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDK-SKKKGQEEKQPKKQPKK 233
+ + +R R E + + R R K ++ E I EE+K + ++ Q K+ +K+ +
Sbjct: 309 REAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE 368
Query: 234 DEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRN 293
+ + + E++ + + ++++ K++E K+ + +T + ++ EKK + +
Sbjct: 369 ERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDK- 427
Query: 294 FQTAHRRNMLKGQHEKEAADRKRKQEEQ 321
QTA + + + K A R++ QE++
Sbjct: 428 LQTAVLKKQGEEKGTKVQAKREKLQEDK 455
Score = 50.4 bits (119), Expect = 2e-06
Identities = 55/253 (21%), Positives = 108/253 (42%), Gaps = 15/253 (5%)
Query: 70 KPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKED---TDHEE 126
+P + + +G EI ++ K++ ++ A + + +E EE+E +++D D
Sbjct: 237 EPKQEEEREQGSDEISHHEKMEEEDKERAEAER---ARLEAEERERIKAEQDKKIADERA 293
Query: 127 KASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAAT 186
+ E+ A + +A R R R+ EK+ E + + + +R R
Sbjct: 294 RIEAEEKAAAQERERREAEERERMREEEKRAAEERQRI-----KEEEKRAAEERQRIKEE 348
Query: 187 EVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRK 246
E + + R R K ++ E E++ K K +E+K+ K+ +K Q+ + K K
Sbjct: 349 EKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEK 408
Query: 247 EPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQ 306
K EGK E K + EE+G + + KR+ + + ++ +K
Sbjct: 409 VEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKG--TKVQAKREKLQEDKPTFKKEEIK-- 464
Query: 307 HEKEAADRKRKQE 319
EK D++ K+E
Sbjct: 465 DEKIKKDKEPKEE 477
Score = 48.9 bits (115), Expect = 6e-06
Identities = 48/229 (20%), Positives = 98/229 (42%), Gaps = 8/229 (3%)
Query: 100 KQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVET 159
+ N +++ E EKE S+ + E E VTK+ + A +K EK+ E
Sbjct: 136 RMQNDTAENETTEKEEK-SESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEE 194
Query: 160 EEAGVV-TTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSK 218
EE + V + V K V + G+ + E + ++E
Sbjct: 195 EEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHH 254
Query: 219 KKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKK--EGKKEVESKRKNLAKTGVTSTSDSE 276
+K +EE + + + ++ +E ++ + E DKK + + +E++ K A+ ++
Sbjct: 255 EKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEER 314
Query: 277 EEGDDQE----GEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQ 321
E ++E E++R + A R +K + ++ A +R+R +EE+
Sbjct: 315 ERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEE 363
Score = 48.9 bits (115), Expect = 6e-06
Identities = 63/275 (22%), Positives = 118/275 (42%), Gaps = 41/275 (14%)
Query: 62 SENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKED 121
+E +E+ + KR + ++K ++AA ++ ++ EEK + ++
Sbjct: 311 AEERERMREEEKRAA--------EERQRIKEEEKRAAEERQR----IKEEEKRAAEERQR 358
Query: 122 TDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLK------ 175
EEK + E+ +A KA +KR KQ+E ++ + T ++
Sbjct: 359 IKEEEKRAAEERQRARAEEEEKAKVEEQKRN--KQLEEKKHAMQETKIKGEKVEQKIEGK 416
Query: 176 -VSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKD 234
V+ K+ + + + K +G K K E +EDK K +E K K KKD
Sbjct: 417 WVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREK---LQEDKPTFKKEEIKDEKI--KKD 471
Query: 235 EEGQKEEDKPRKEPDKKEGKKEVES--------KRKNLAKTGVTSTSDSEEEGDDQEGEK 286
+E ++E + D+K+G EV+S K K+ T + + + EG
Sbjct: 472 KEPKEEV---KSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAP 528
Query: 287 KRKGGRNFQTAHRRNMLKGQHEKEAADR-KRKQEE 320
+ + G+ + RR +G+ E E ++ K+KQ+E
Sbjct: 529 QVEAGKRLEELRRR---RGETESEEFEKLKQKQQE 560
Score = 47.0 bits (110), Expect = 2e-05
Identities = 68/328 (20%), Positives = 131/328 (39%), Gaps = 39/328 (11%)
Query: 26 DEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYGKPNKRKGFNEGLWEID 85
+ VPD K T + G E AFL K ++K F+ + +
Sbjct: 72 NSVPDEEAKTTTTNTQVE--GDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDAS 129
Query: 86 --------NNPKVKFSSQQAATKQSNASSDVEVEEKET---SVSKEDTDHEEKASNEDVT 134
N + + + K + E+EE ET S K D E+ ED
Sbjct: 130 LSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKE 189
Query: 135 KAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPR 194
K + + +RG + + +V EE TT + + +S K G+ ++ E K + R
Sbjct: 190 KEEE--EEEKPKRGSIGENQVEVMVEEK---TTESQEETVVMSLKNGQISSEEPKQEEER 244
Query: 195 --GRPKMVKQPCPSESDIITEEDKSKKKGQE---EKQPKKQPKKDEEGQKEEDKPRKEPD 249
G ++ S + + EEDK + + + E + +++ K +++ + +++ R E +
Sbjct: 245 EQGSDEI------SHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAE 298
Query: 250 KKEGKKEVESKR-------KNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNM 302
+K +E E + + K +EE E++R + A R
Sbjct: 299 EKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQR 358
Query: 303 LKGQHEKEAADRKR---KQEEQMETEHQ 327
+K + ++ A +R+R ++EE+ + E Q
Sbjct: 359 IKEEEKRAAEERQRARAEEEEKAKVEEQ 386
Score = 41.2 bits (95), Expect = 0.001
Identities = 55/275 (20%), Positives = 117/275 (42%), Gaps = 38/275 (13%)
Query: 62 SENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATK--QSNASSDVEVEEKETSVSK 119
+E EK K R + +EI+ V S Q+ + + N D E EE+E K
Sbjct: 144 NETTEKEEKSESR----QERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPK 199
Query: 120 EDTDHEEKAS---NEDVTKAVDITTPKAARRGR------KRKAEKQVETEEAGVVTTATA 170
+ E + E T++ + T + + G+ K++ E++ ++E
Sbjct: 200 RGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEE 259
Query: 171 SVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQ 230
+ +R R A E + K K+ + E++ E+ ++++ + E + +++
Sbjct: 260 EDKERAEAERARLEAEERERIKAEQDKKIADERARIEAE---EKAAAQERERREAEERER 316
Query: 231 PKKDEEGQKEEDKPRKEPDKK--EGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKR 288
+++E+ EE + KE +K+ E ++ ++ + K A EE +E EK+
Sbjct: 317 MREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAA----------EERQRIKEEEKR- 365
Query: 289 KGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQME 323
A R + + E++A ++K+ +Q+E
Sbjct: 366 -------AAEERQRARAEEEEKAKVEEQKRNKQLE 393
Score = 37.4 bits (85), Expect = 0.019
Identities = 37/184 (20%), Positives = 83/184 (45%), Gaps = 12/184 (6%)
Query: 89 KVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRG 148
K F ++ ++ + + E K K+ + + E +T + T +R G
Sbjct: 455 KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPG 514
Query: 149 RKRKAEKQVETEEAGVVTTATASVNLK-VSPKRGRPAATEVKIPKPRGRPKMVKQPCPSE 207
+ V+T+EA A L+ + +RG + E + + K +Q E
Sbjct: 515 GRAS----VDTKEAEGAPQVEAGKRLEELRRRRGETESEEFE------KLKQKQQEAALE 564
Query: 208 SDIITEEDKSKKKG-QEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAK 266
+ + ++ + ++K +EE+Q +KQ + D + ++EE+K R + + + + E KR+ + +
Sbjct: 565 LEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPE 624
Query: 267 TGVT 270
G++
Sbjct: 625 DGLS 628
Score = 30.4 bits (67), Expect = 2.3
Identities = 60/307 (19%), Positives = 118/307 (38%), Gaps = 63/307 (20%)
Query: 63 ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVE----VEEKETSVS 118
+ +EK +++ E + ++K ++AA ++ A ++ E VEE++ +
Sbjct: 332 KEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQ 391
Query: 119 KEDTDH---EEKASNEDVTKAVD--ITTPKAARRGRKRKAEKQVETEEAGVVTTATASVN 173
E+ H E K E V + ++ K A+ + + A + + EE G A
Sbjct: 392 LEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKL 451
Query: 174 LKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDII----------------TEEDKS 217
+ P + + KI K + + VK + TE S
Sbjct: 452 QEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFS 511
Query: 218 KKKGQ--------------------EEKQPKKQPKKDEEGQKEEDKPRKEP-DKKEGKKE 256
+ G+ EE + ++ + EE +K + K ++ + +E KK+
Sbjct: 512 RPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKK 571
Query: 257 VESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEK---EAAD 313
E +RK L EEE ++ K+ + R + + LK + E+ EAA+
Sbjct: 572 REERRKVL-----------EEE---EQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAE 617
Query: 314 RKRKQEE 320
+++K E
Sbjct: 618 KRQKMPE 624
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 58.9 bits (141), Expect = 6e-09
Identities = 68/250 (27%), Positives = 102/250 (40%), Gaps = 46/250 (18%)
Query: 58 IFPYSENKEKYG--------KPNKRKGFNEGL-WEIDNNPKVKFSSQQAATKQSNASS-- 106
+ P ++N E G K K NEG E K +A Q A+
Sbjct: 33 VSPAADNPEMSGGGAPAEETKGTAGKAINEGPPTESGKQEKAPAEDGMSAELQGEANGLD 92
Query: 107 DVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVT 166
+V+VE + + KED + E K ED K T ++ RK E + E +EA
Sbjct: 93 EVKVESQREAGGKEDAEAELK--KEDGEKE---ETTVGSQEMTGRKEETKSEPKEAEEKE 147
Query: 167 TATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQ 226
+ AS K K +P + + R +P E EE+ +K QEE
Sbjct: 148 STLASEKQKAEEKEAKPESGQKADANDRDKP---------EPKATVEEEDAKTASQEETG 198
Query: 227 PKKQ----PKK---DEEGQKE------EDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTS 273
+K+ PK+ DEE + E ED+ + EP + +GK+E AK G +
Sbjct: 199 QRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEE--------AKHGAKEEA 250
Query: 274 DSEEEGDDQE 283
D++EE +D E
Sbjct: 251 DAKEEAEDAE 260
Score = 49.7 bits (117), Expect = 4e-06
Identities = 58/262 (22%), Positives = 109/262 (41%), Gaps = 37/262 (14%)
Query: 98 ATKQSNASSDV--EVEEKETSVSKEDTDHEEKASNEDVT--------------KAVDITT 141
A +S+ S++ ++E+KE +S++ T A N +++ KA++
Sbjct: 5 AVGESDCSAEAREKMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEGP 64
Query: 142 PKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKR--GRPAATEVKIPKPRGRPK- 198
P + + K AE + E G A +KV +R G E ++ K G +
Sbjct: 65 PTESGKQEKAPAEDGMSAELQG---EANGLDEVKVESQREAGGKEDAEAELKKEDGEKEE 121
Query: 199 -------MVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKK 251
M + ++S+ E+K E+++ +++ K E GQK + R +P+ K
Sbjct: 122 TTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEPK 181
Query: 252 EGKKEVESKRKNLAKTG---VTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHE 308
+E ++K + +TG ST E+ D++ + +K + G+ E
Sbjct: 182 ATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEE 241
Query: 309 -----KEAADRKRKQEEQMETE 325
KE AD K + E+ E E
Sbjct: 242 AKHGAKEEADAKEEAEDAEEAE 263
Score = 46.6 bits (109), Expect = 3e-05
Identities = 42/186 (22%), Positives = 75/186 (40%), Gaps = 21/186 (11%)
Query: 93 SSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRK 152
S + K+ S E EEKE++++ E EEK + + G+K
Sbjct: 126 SQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPE--------------SGQKAD 171
Query: 153 AEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIIT 212
A + + E V A + + + +TE PK + + K S+ ++
Sbjct: 172 ANDRDKPEPKATVEEEDAKTASQEETGQRKECSTE---PKEKATDEEAK--AESQKAVVE 226
Query: 213 EEDKSKKKGQEEKQPKKQPKKDEEGQKE--EDKPRKEPDKKEGKKEVESKRKNLAKTGVT 270
+E K++ K + K+ K K+E KE ED EP ++E + +++ GV
Sbjct: 227 DEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDVEKEPEGGAGVI 286
Query: 271 STSDSE 276
+S E
Sbjct: 287 PSSPEE 292
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 58.2 bits (139), Expect = 1e-08
Identities = 43/210 (20%), Positives = 100/210 (47%), Gaps = 9/210 (4%)
Query: 120 EDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPK 179
+D D +++ D + T K R RKR E++ + +E ++ +
Sbjct: 70 KDADGDDRQRERDRVRE---KTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRE 126
Query: 180 RGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQE-EKQPKKQPKKDEEGQ 238
R + E + + RGR + + E + TE+D+ ++ E E++ ++ +K +E +
Sbjct: 127 REKQKGRERE--RDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERE 184
Query: 239 KEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGD---DQEGEKKRKGGRNFQ 295
E D+ R+ +KE +++ + +R KT +++ EG+ D+ E++R R +
Sbjct: 185 TERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKE 244
Query: 296 TAHRRNMLKGQHEKEAADRKRKQEEQMETE 325
R+ + + ++ +RK++++E+ + E
Sbjct: 245 RDRERDRKEERKKERKKERKKERKEKKKEE 274
Score = 47.4 bits (111), Expect = 2e-05
Identities = 50/205 (24%), Positives = 89/205 (43%), Gaps = 39/205 (19%)
Query: 100 KQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVET 159
K++N + D EK+T + + D + E++ E + D + R R+++ E+Q E
Sbjct: 107 KETNRNRD---REKQTEIER-DREREKQKGRE---RERDRGRERERDRDREKERERQTEK 159
Query: 160 EEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKK 219
+ G T T R R E + + R R + ++ ++D E D+ +K
Sbjct: 160 DRDGQRETETERER-----DREREKQKERETERDRDRQRDTEKERERQTD--RERDRQRK 212
Query: 220 -----------KGQEEKQPKKQPKKDEEGQKEEDKPR--KEPDKKEGKKEVESKRKNLAK 266
+G+ E +++ ++D + KE D+ R KE KKE KKE + +RK K
Sbjct: 213 TQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKK 272
Query: 267 TGVTSTSDSEEEGDDQEGEKKRKGG 291
+ + +KKRK G
Sbjct: 273 E------------EKRREDKKRKWG 285
Score = 43.9 bits (102), Expect = 2e-04
Identities = 35/150 (23%), Positives = 68/150 (45%), Gaps = 16/150 (10%)
Query: 187 EVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRK 246
EV IP R ++ Q P + ++ K + + +++ + E+ +KE D+ RK
Sbjct: 42 EVTIPLDFSRGRLGSQESPRSWGL----GQAHKDADGDDRQRERDRVREKTEKERDRDRK 97
Query: 247 EPDKKEGKKEVESKRKNLAKTGVTSTSDSEEE-----------GDDQEGEKKRKGGRNFQ 295
D++ +KE E+ R + D E E G ++E ++ R+ R Q
Sbjct: 98 R-DRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQ 156
Query: 296 TAHRRNMLKGQHEKEAADRKRKQEEQMETE 325
T R+ + + DR+R+++++ ETE
Sbjct: 157 TEKDRDGQRETETERERDREREKQKERETE 186
Score = 40.8 bits (94), Expect = 0.002
Identities = 41/194 (21%), Positives = 81/194 (41%), Gaps = 35/194 (18%)
Query: 63 ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVE-EKETSVSKED 121
E +++ G+ +R E E D + + + Q + ++ E E ++E KE
Sbjct: 126 EREKQKGRERERDRGRER--ERDRDREKERERQTEKDRDGQRETETERERDREREKQKER 183
Query: 122 TDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRG 181
++ D K + T + R RK + E+Q ET+ G +R
Sbjct: 184 ETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREG---------------ERE 228
Query: 182 RPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSK-KKGQEEKQPKKQPKKDEEGQKE 240
E + + RG+ E D+ + +K + +K+ KK+ KK+ + +K+
Sbjct: 229 TDRRRERQRDRDRGK----------------ERDRERDRKEERKKERKKERKKERKEKKK 272
Query: 241 EDKPRKEPDKKEGK 254
E+K R++ +K G+
Sbjct: 273 EEKRREDKKRKWGE 286
Score = 40.0 bits (92), Expect = 0.003
Identities = 24/117 (20%), Positives = 58/117 (49%), Gaps = 1/117 (0%)
Query: 213 EEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTST 272
+E ++ + EKQ + + ++ E QK ++ R ++E ++ E +R+ +
Sbjct: 105 KEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQ 164
Query: 273 SDSEEEGD-DQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEHQT 328
++E E + D+E EK+++ +R+ K + + +R R+++ Q E + +T
Sbjct: 165 RETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRET 221
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 57.8 bits (138), Expect = 1e-08
Identities = 50/210 (23%), Positives = 89/210 (42%), Gaps = 16/210 (7%)
Query: 113 KETSVSKEDTDHEEKASNEDVTKAVDITTP--KAARRGRKRKAEKQVETEEAGVVTTATA 170
K + + D E K + ++ + TP K R RK + + + E + T+A A
Sbjct: 3 KRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQA 62
Query: 171 SVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITE-----EDKSKKKGQEEK 225
K K G K+ + P SE +I+ ED ++K G++++
Sbjct: 63 VAETKQEAVVEEDYNENAK----NGEAKITEAPA-SEKEIVEVKEENIEDATEKGGEKKE 117
Query: 226 QPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGE 285
+ K +EE QKE+++ + E + GK++ + K + K E+ + ++G+
Sbjct: 118 AVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGK 177
Query: 286 KKRKGGRNFQTAHRRNMLKGQHEKEAADRK 315
K G N + KG+ EKE DRK
Sbjct: 178 KGEDGKGNGEDGKE----KGEDEKEEEDRK 203
Score = 52.4 bits (124), Expect = 6e-07
Identities = 58/256 (22%), Positives = 106/256 (41%), Gaps = 42/256 (16%)
Query: 88 PKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARR 147
PK SS++ TK +++ + + +K++ EE + IT A+ +
Sbjct: 36 PKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEK 95
Query: 148 GRKRKAEKQVE--TEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCP 205
E+ +E TE+ G ++ A EVK K ++
Sbjct: 96 EIVEVKEENIEDATEKGG---------------EKKEAVAAEVK--NEEEDQKEDEEDQN 138
Query: 206 SESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEG-----KKEVESK 260
E +EDK +K ++ K+ K +K E+ +++ED + E K G K E E +
Sbjct: 139 EEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKE 198
Query: 261 RKNLAKTG-VTSTSDSEEEGDDQEG--------EKKRKGGRNFQTAHRRNMLKGQHEKEA 311
++ +TG D +E+GD +EG EK+R+ G+ + G +E+EA
Sbjct: 199 EEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDE---------GGNEEEA 249
Query: 312 ADRKRKQEEQMETEHQ 327
K +E+ E + +
Sbjct: 250 GKEKEDLKEEEEGKEE 265
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/180 (22%), Positives = 70/180 (38%), Gaps = 25/180 (13%)
Query: 83 EIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASN----EDVTKAVD 138
E+ N + + ++ ++ + + +EK KED + EK + ED K D
Sbjct: 122 EVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGED 181
Query: 139 ITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPK 198
G K + + E EE T N K + +VK+
Sbjct: 182 -----GKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKV-------- 228
Query: 199 MVKQPCPSESDIITEEDKSKKKGQEEKQPK-KQPKKDEEGQKEEDKPRKEPDKKEGKKEV 257
E + E+ K + G EE+ K K+ K+EE KEED+ +++ KKE + +
Sbjct: 229 -------KEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQSI 281
>gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [Homo
sapiens]
Length = 1447
Score = 57.4 bits (137), Expect = 2e-08
Identities = 53/242 (21%), Positives = 106/242 (43%), Gaps = 43/242 (17%)
Query: 109 EVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKR-----KAEKQVETEEAG 163
E+E+ T+ EEK +D+TK V PK ++R RKR ++++Q EE
Sbjct: 1210 ELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKR 1269
Query: 164 VVTTATASVNLKVSP----KRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKK 219
+ + + + SP KRGRP PKP G ++P K+ K
Sbjct: 1270 LKEDILENEDEQNSPPKKGKRGRP-------PKPLGGGTPKEEPTM----------KTSK 1312
Query: 220 KGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGK--KEVESKRKNLAKTGVTSTSDSEE 277
KG ++K P+++EE +++ ++ K+ + + + + ++ + + ST + +
Sbjct: 1313 KGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQ 1372
Query: 278 EG--------DDQEGEKKRKGGRNFQTAHRRN-------MLKGQHEKEAADRKRKQEEQM 322
+G + +K + GR+ Q A + N + +G + ++ +EE++
Sbjct: 1373 KGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEV 1432
Query: 323 ET 324
T
Sbjct: 1433 ST 1434
Score = 47.8 bits (112), Expect = 1e-05
Identities = 68/292 (23%), Positives = 113/292 (38%), Gaps = 30/292 (10%)
Query: 35 PPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKY--GKP---NKRKGFNEGLWEIDNNPK 89
P LP FF + F K+ P E K + GKP N N+ L +
Sbjct: 1088 PKDPVLPARFFTQPDKNFSNTKNYLP-PEMKSFFTPGKPKTTNVLGAVNKPLSSAGKQSQ 1146
Query: 90 VKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGR 149
K S + + S++S+ + + + DH E NED T + + K+ +R
Sbjct: 1147 TKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSE---NEDYTMSSPLPGKKSDKRDD 1203
Query: 150 KRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATE-VKIPKPRGRPKMVKQ-PCPSE 207
++E T T + K G T+ V+ KP+G + K+ SE
Sbjct: 1204 SDLVRSELEKPRGRKKTPVT-----EQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASE 1258
Query: 208 SDIITEEDKSKKKG---QEEKQPKKQPKKDEEGQKEE----DKPRKEPDKKEGKKEVESK 260
SD ++ + K + E + PKK + G+ + P++EP K KK SK
Sbjct: 1259 SDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKK--GSK 1316
Query: 261 RKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAA 312
+K+ + EEE + Q G ++K RR + + + +A
Sbjct: 1317 KKS-----GPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSA 1363
Score = 30.0 bits (66), Expect = 3.0
Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 9/59 (15%)
Query: 94 SQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRK 152
S+QAATK++++S +V+V + + V +D EE T+ +++T RR KR+
Sbjct: 1396 SKQAATKENDSSEEVDVFQGSSPV--DDIPQEE-------TEEEEVSTVNVRRRSAKRE 1445
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 56.2 bits (134), Expect = 4e-08
Identities = 62/263 (23%), Positives = 117/263 (44%), Gaps = 18/263 (6%)
Query: 65 KEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEK--ETSVSKEDT 122
K K K NK+ +E + DN+ K+K S+ ++ +S SD ++ + + K
Sbjct: 151 KGKAQKSNKKWDGSEE--DEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKP 208
Query: 123 DHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGR 182
++ NED + I T + +K + K+ + E+A + + K + G+
Sbjct: 209 GPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKL-----RKLKEKEELETGK 263
Query: 183 PAATEVKIPKPRGRPKMVKQPCPSESDII-TEEDKSKKKGQEEKQPKKQPKKDEEGQKEE 241
++ K + + + VK ++ +I E+K++ E + KK ++ +K+
Sbjct: 264 KDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKG 323
Query: 242 DKPRKEPDKKEG--KKEVESKRKNLAKTGVTSTSDSEEEGDD----QEGEKKRKGGRNFQ 295
+K KE +KK+G K V++ ++ LAK EE + +E E KRK +
Sbjct: 324 EKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLE 383
Query: 296 TAHRRNMLKGQHEKEAADRKRKQ 318
R K Q EKE +R +K+
Sbjct: 384 QEKRER--KKQKEKERKERLKKE 404
Score = 53.1 bits (126), Expect = 3e-07
Identities = 61/275 (22%), Positives = 112/275 (40%), Gaps = 12/275 (4%)
Query: 58 IFPYSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSV 117
+ P SE EK P + NEG + + K K ++ ++ S V+ + ++
Sbjct: 291 VIPASE--EKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEAL 348
Query: 118 SK-EDTDHEEKASNEDVTKAVDITTPKAARRGR----KRKAEKQVETEEAGVVTTATASV 172
+K ++ + +K E+ K ++ K R KR+ +KQ E E + +
Sbjct: 349 AKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLL 408
Query: 173 NLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPK 232
R R AT +K+ + +G K P + I EDK +KK ++ + K+ +
Sbjct: 409 TKSQREARARAEAT-LKLLQAQGVEVPSKDSLPKKRPIY--EDKKRKKIPQQLESKEVSE 465
Query: 233 KDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGR 292
E E + P+K+E VE + + T D E D+E EK
Sbjct: 466 SMELCAAVEVMEQGVPEKEETPPPVEPEEEE--DTEDAGLDDWEAMASDEETEKVEGNKV 523
Query: 293 NFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEHQ 327
+ + + + E+E D + ++EE+ E E +
Sbjct: 524 HIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESE 558
Score = 46.2 bits (108), Expect = 4e-05
Identities = 53/238 (22%), Positives = 91/238 (38%), Gaps = 30/238 (12%)
Query: 57 DIFPYSENKEKYGKPNKR-KGFNEGLWEIDNNPKVKFSSQQAATKQSNASSD-------- 107
D F S +K + NK G + D + K+K +Q+ A K+
Sbjct: 191 DEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKL 250
Query: 108 ---VEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGV 164
E EE ET + E + E+ T +T + KAE E+
Sbjct: 251 RKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDN- 309
Query: 165 VTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEE 224
K K+ + E + K +G K + + EE++ +K+ +EE
Sbjct: 310 -----EGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEE 364
Query: 225 ------------KQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVT 270
K+ ++ ++ E +K+++K RKE KKEGK +S+R+ A+ T
Sbjct: 365 RIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEAT 422
Score = 43.9 bits (102), Expect = 2e-04
Identities = 38/208 (18%), Positives = 89/208 (42%), Gaps = 29/208 (13%)
Query: 111 EEKETSVSKEDTDHEEKASNEDVTKAVDIT---TPKAARRGRKRKAEKQVETEEAGVVTT 167
E+K+ + + +E + + ++ AV++ P+ + E++ +TE+AG+
Sbjct: 447 EDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDW 506
Query: 168 ATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQP 227
+ + + G EVK E+ EE++ +++ EE +
Sbjct: 507 EAMASDEETEKVEGNKVHIEVK-----------------ENPEEEEEEEEEEEEDEESEE 549
Query: 228 KKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKK 287
+++ + + EG + +++ K D+K+ K ++ K +SDSE + DD +++
Sbjct: 550 EEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSK------EMSSDSEYDSDDDRTKEE 603
Query: 288 RKGGRNFQTAHRRNMLKGQHEKEAADRK 315
R + + +R + +H K K
Sbjct: 604 RAYDKAKRRIEKRRL---EHSKNVNTEK 628
Score = 42.7 bits (99), Expect = 4e-04
Identities = 50/218 (22%), Positives = 91/218 (41%), Gaps = 37/218 (16%)
Query: 111 EEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATA 170
+ K +K+D D + A+ + A P+ ++ G+K+K +K+ + +E ++
Sbjct: 6 KNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSK-GKKKKEKKKQDFDEDDIL----- 59
Query: 171 SVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQ 230
K + E + K R + +P + + T +DK KKKGQ+ K KQ
Sbjct: 60 --------KELEELSLEAQGIKA-DRETVAVKPTENNEEEFTSKDK-KKKGQKGK---KQ 106
Query: 231 PKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKG 290
D + ++ EDK +SK K AK V S S+++ D + KK KG
Sbjct: 107 SFDDNDSEELEDK--------------DSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKG 152
Query: 291 GRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEHQT 328
+ G E E +K K+ ++ + ++
Sbjct: 153 ----KAQKSNKKWDGSEEDEDNSKKIKERSRINSSGES 186
>gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]
Length = 553
Score = 55.8 bits (133), Expect = 5e-08
Identities = 48/188 (25%), Positives = 81/188 (43%), Gaps = 14/188 (7%)
Query: 8 GDLIFAKMKGYPHWPARVDEVPDGAVKPPTNK-LPIFFFGTHETAFLGPKDIFPYSENKE 66
GDL++ K+ YP WP ++ P KP K + FFGT + A++ + + PY +KE
Sbjct: 9 GDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKE 68
Query: 67 KYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEE 126
+ K NK K F + + ++ ++ + + T N+S D S+ ++ E+
Sbjct: 69 EMIKINKGKRFQQAVDAVEE--FLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEK 126
Query: 127 KASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSP-KRGRPAA 185
+ + K K G+KR + E + A + SP KRGRP
Sbjct: 127 RKLSLSEGK-----VKKNMGEGKKRVSSGSSERGSKSPLKRAQ-----EQSPRKRGRPPK 176
Query: 186 TEVKIPKP 193
E + P
Sbjct: 177 DEKDLTIP 184
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 55.5 bits (132), Expect = 7e-08
Identities = 62/311 (19%), Positives = 118/311 (37%), Gaps = 57/311 (18%)
Query: 63 ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDT 122
EN ++ GK K K E +V + K+ + D + E + K D
Sbjct: 1268 ENDKEKGK-EKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKERTPKSDK 1326
Query: 123 DHEE-KASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRG 181
+ E+ K + + T P A + + + ++ + E + + N+K K
Sbjct: 1327 EKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAKEMKSKENVKGGEKT- 1385
Query: 182 RPAATEVKIPKPRG----------RPKMVKQPCPSESDIITEE----------------- 214
P + +K P PR R K+ P PS S + +
Sbjct: 1386 -PVSGSLKSPVPRSDIPEPEREQKRRKIDTHPSPSHSSTVKDSLIELKESSAKLYINHTP 1444
Query: 215 ---DKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKE-------------PDKKEGKKEVE 258
KSK++ ++K K ++ E +K+++K RKE PD + +KE
Sbjct: 1445 PPLSKSKEREMDKKDLDKSRERSREREKKDEKDRKERKRDHSNNDREVPPDLTKRRKEEN 1504
Query: 259 -----SKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKG-----QHE 308
SK K+ + ++ ++E + + K KG +F++ + G +H+
Sbjct: 1505 GTMGVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKGSDSFKSEKMDKISSGGKKESRHD 1564
Query: 309 KEAADRKRKQE 319
KE ++K K++
Sbjct: 1565 KEKIEKKEKRD 1575
Score = 39.7 bits (91), Expect = 0.004
Identities = 54/262 (20%), Positives = 94/262 (35%), Gaps = 45/262 (17%)
Query: 85 DNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKA 144
D P+ +S Q +SS + K S E+TD + S V KAV+
Sbjct: 1190 DPPPRNAVASVQNGPGGGPSSSSIGSASKSDESSTEETDKSRERSQCGV-KAVN------ 1242
Query: 145 ARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPC 204
K T G + + N A E K + + K K+
Sbjct: 1243 ----------KASSTTPKGNSSNGNSGSN-------SNKAVKENDKEKGKEKEKEKKEKT 1285
Query: 205 PSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNL 264
P+ T E + K +EK +++P KDE+ ++ +++ K +KE K+ E +
Sbjct: 1286 PAT----TPEARVLGKDGKEKPKEERPNKDEKARETKERTPKSDKEKEKFKKEEKAKDEK 1341
Query: 265 AKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQH----------------- 307
KT V + + ++E E R+ + + N+ G+
Sbjct: 1342 FKTTVPNAESKSTQEREREKEPSRERDIAKEMKSKENVKGGEKTPVSGSLKSPVPRSDIP 1401
Query: 308 EKEAADRKRKQEEQMETEHQTT 329
E E ++RK + H +T
Sbjct: 1402 EPEREQKRRKIDTHPSPSHSST 1423
Score = 34.3 bits (77), Expect = 0.16
Identities = 42/194 (21%), Positives = 76/194 (39%), Gaps = 23/194 (11%)
Query: 83 EIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTP 142
+ID +P SS + S +E++E + T S E D+
Sbjct: 1411 KIDTHPSPSHSS-------TVKDSLIELKESSAKLYINHTPPPLSKSKEREMDKKDLDKS 1463
Query: 143 KAARRGRKRKAEK---QVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKM 199
+ R R++K EK + + + + + + + G ++ K P
Sbjct: 1464 RERSREREKKDEKDRKERKRDHSNNDREVPPDLTKRRKEENGTMGVSKHKSESP------ 1517
Query: 200 VKQPCPSESDIITEEDKS--KKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKE----- 252
+ P P+E D + KS K+KG + + +K K G+KE +++ +KKE
Sbjct: 1518 CESPYPNEKDKEKNKSKSSGKEKGSDSFKSEKMDKISSGGKKESRHDKEKIEKKEKRDSS 1577
Query: 253 GKKEVESKRKNLAK 266
G KE + K+ K
Sbjct: 1578 GGKEEKKHHKSSDK 1591
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 55.5 bits (132), Expect = 7e-08
Identities = 67/279 (24%), Positives = 107/279 (38%), Gaps = 51/279 (18%)
Query: 89 KVKFSSQQAATKQSNASSDVEVEEKE-TSVSKEDTDHEEKASNEDVTKAVDI-------- 139
KVK ++ + Q S E E+KE +VSK HE+K +DI
Sbjct: 229 KVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSK----HEQKDQYAFCRYMIDIFVHGDLKP 284
Query: 140 ----------TTPKAAR-----------RGRKRKAEKQVETEEAGVVTTATASVNLKVSP 178
T +A+R G K+KAEK+V +E T ++K
Sbjct: 285 GQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSE-----TKKKEKEDIKKKS 339
Query: 179 KRGRPAATEVKIPKPRGRPKM----VKQPCPSESDIITEEDKSKKKGQEEKQPK--KQPK 232
++ E K P K + ++ D E+ K KK E +QPK KQ K
Sbjct: 340 EKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEK 399
Query: 233 KDE--EGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDD----QEGEK 286
K++ E K K P K+ K + E ++ + + ++E ++ +
Sbjct: 400 KEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIR 459
Query: 287 KRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETE 325
K K G+ + +KG+ EK A K K+ E + E
Sbjct: 460 KEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDE 498
Score = 52.4 bits (124), Expect = 6e-07
Identities = 66/274 (24%), Positives = 120/274 (43%), Gaps = 20/274 (7%)
Query: 62 SENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEK--ETSVSK 119
SE K+K + K+K E +++ K S + T + A + + +EK ++ +K
Sbjct: 325 SETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTK 384
Query: 120 EDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPK 179
+ + E+ + K + K+ ++ ++KQV+ + A VS K
Sbjct: 385 KPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGA-----VSIK 439
Query: 180 RGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQP----KKQP--KK 233
+ P E K K + ++ K+ S I+ +DK KG+EEK P +K+P KK
Sbjct: 440 KAVPGKKEEKTTKTVEQ-EIRKEKSGKTSSIL--KDKEPIKGKEEKVPASLKEKEPETKK 496
Query: 234 DEEGQKEEDKPRKEPDKKEGKKE--VESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGG 291
DE+ K + + +P + +GKKE E + K AK ++ ++ D + EK G
Sbjct: 497 DEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQ-DIVKPEKTVSHG 555
Query: 292 RNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETE 325
+ + + + EK A + K+ E E E
Sbjct: 556 KPEEKV-LKQVKAVTIEKTAKPKPTKKAEHRERE 588
Score = 44.3 bits (103), Expect = 2e-04
Identities = 48/183 (26%), Positives = 75/183 (40%), Gaps = 28/183 (15%)
Query: 123 DHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGR 182
D E+ +ED K P + K K EKQ + E + KV+ K
Sbjct: 118 DEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPER---------KIQTKVTHKE-- 166
Query: 183 PAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEED 242
K +G+ K+ ++ P E +E KK+ E K K+ KK + +K E+
Sbjct: 167 ---------KEKGKEKVREKEKP-EKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEE 216
Query: 243 KPRKE--PDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRR 300
K +KE K+E K+ +K K + K T +E +D+E K + Q A R
Sbjct: 217 KTKKEVKGGKQEKVKQTAAKVKEVQK-----TPSKPKEKEDKEKAAVSKHEQKDQYAFCR 271
Query: 301 NML 303
M+
Sbjct: 272 YMI 274
Score = 43.9 bits (102), Expect = 2e-04
Identities = 52/258 (20%), Positives = 100/258 (38%), Gaps = 13/258 (5%)
Query: 71 PNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASN 130
P ++K ++ E P+ K ++ ++ V +EK + E+K
Sbjct: 137 PLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKP 196
Query: 131 EDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKI 190
E T A + K A + ++ ++ ++ V TA ++ +P + + + K
Sbjct: 197 ETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKA 256
Query: 191 PKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKP---RKE 247
+ K C DI D K GQ P P ++ + P KE
Sbjct: 257 AVSKHEQKDQYAFCRYMIDIFVHGD--LKPGQSPAIPPPLP-TEQASRPTPASPALEEKE 313
Query: 248 PDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQH 307
+KK+ +K+V S+ K K + S+ E D +K++ G+ +T + Q
Sbjct: 314 GEKKKAEKKVTSETKKKEKEDIKKKSEKETAID----VEKKEPGKASETKQGTVKIAAQ- 368
Query: 308 EKEAADRKRKQEEQMETE 325
AA + K+E+ +T+
Sbjct: 369 --AAAKKDEKKEDSKKTK 384
Score = 42.4 bits (98), Expect = 6e-04
Identities = 49/248 (19%), Positives = 104/248 (41%), Gaps = 13/248 (5%)
Query: 70 KPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKAS 129
KP K+ E + E P+ K +++ K A E +KE K++ + A
Sbjct: 179 KPEKKATHKEKI-EKKEKPETKTLAKEQK-KAKTAEKSEEKTKKEVKGGKQEKVKQTAAK 236
Query: 130 NEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVK 189
++V K + PK + +++ A + E ++ + + K G+ A
Sbjct: 237 VKEVQKTP--SKPKE-KEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPP 293
Query: 190 IPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPD 249
+P + +P P+ + +E + KK ++ K+ +K++ +K E + + +
Sbjct: 294 LPT-----EQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVE 348
Query: 250 KKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEK 309
KKE K E+K + K + + +E+ +D +K +K Q ++ K +H +
Sbjct: 349 KKEPGKASETK-QGTVKIAAQAAAKKDEKKED--SKKTKKPAEVEQPKGKKQEKKEKHVE 405
Query: 310 EAADRKRK 317
A K++
Sbjct: 406 PAKSPKKE 413
Score = 35.4 bits (80), Expect = 0.072
Identities = 26/133 (19%), Positives = 63/133 (47%), Gaps = 16/133 (12%)
Query: 208 SDIITEEDKSKKKGQEE-------KQPKKQPKKDEEGQKEEDKPRKE-------PDKKEG 253
SDII+ ED+ G E+ + P ++ + ++ ++++KP ++ +K++G
Sbjct: 111 SDIISSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKG 170
Query: 254 KKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNM--LKGQHEKEA 311
K++V K K K + +E+ + + K++K + + + + +KG +++
Sbjct: 171 KEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKV 230
Query: 312 ADRKRKQEEQMET 324
K +E +T
Sbjct: 231 KQTAAKVKEVQKT 243
Score = 35.0 bits (79), Expect = 0.093
Identities = 46/219 (21%), Positives = 87/219 (39%), Gaps = 22/219 (10%)
Query: 95 QQAATKQSNASSDVEVEEKETSVSKEDT-------DHEEKASNEDVTKAVDITTPKAAR- 146
+Q K+ + + +++KE KE+ E +E ++KA PK +
Sbjct: 455 EQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQL 514
Query: 147 RGRKR-KAEKQVETEEAGVVTTATAS-----VNLKVSPKRGRPAATEVKIPKPRGRPKMV 200
+G+K K E Q++ E ++ V + + G+P +K K K
Sbjct: 515 QGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTA 574
Query: 201 KQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKK----- 255
K +++ E S K + + PK + E G+K+ + KE +K K
Sbjct: 575 KPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREE 634
Query: 256 EVESKRKNLAKTGVTSTSDS---EEEGDDQEGEKKRKGG 291
+V +++++L VT ++ +D KK K G
Sbjct: 635 KVSTRKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEG 673
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 55.5 bits (132), Expect = 7e-08
Identities = 61/271 (22%), Positives = 115/271 (42%), Gaps = 41/271 (15%)
Query: 91 KFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRK 150
KF + A + A + +EV+ E +D +E+ SN + KA+
Sbjct: 307 KFDNLDAEADEGWAGAQMEVDYTE---QLNFSDDDEQGSNSPKENNSEDQGSKASENNEN 363
Query: 151 RKAEKQVETEEAGVVTTATASVNLKV----SPKRGRPAATEVKIPKPRGRPKMVKQ---- 202
+K +V ++ A SV KV P + T +P P PK++ Q
Sbjct: 364 KKETDEVSNTKSSSQIPAQPSV-AKVPYGKGPSFNQERGTSSHLPPP---PKLLAQQHPP 419
Query: 203 -----------PCPSESDIITEED--KSKKKGQEE-----KQPKKQPKKDEEGQKEEDKP 244
P PS+ + E++ K +++ Q E ++ +K+ +++E +E+ K
Sbjct: 420 PDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKA 479
Query: 245 R-----KEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGD---DQEGEKKRKGGRNFQT 296
K D+K G E + + + + + E+E + +QE EK+R+ R Q
Sbjct: 480 ACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQ 539
Query: 297 AHRRNMLKGQHEKEAADRKRKQEEQMETEHQ 327
+ + K Q ++ +++RKQE++ E E Q
Sbjct: 540 EKEKELEKEQEKQREMEKERKQEKEKELERQ 570
Score = 48.5 bits (114), Expect = 8e-06
Identities = 41/205 (20%), Positives = 101/205 (49%), Gaps = 14/205 (6%)
Query: 118 SKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVS 177
SK+ E++ + + +I+ R R+ + E+++E + ++ K+
Sbjct: 434 SKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLG 493
Query: 178 PKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEG 237
+P+ E++ R R K ++ E ++ E+++ ++K + EK ++Q +K++E
Sbjct: 494 ILEKQPSPEEIR---EREREKERER----EKELEKEQEQEREK-EREKDRERQQEKEKEL 545
Query: 238 QKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGD-DQEGEKKRKGGRNFQT 296
+KE++K R+ +++ +KE E +R+ + + + E+E + ++E EK + +
Sbjct: 546 EKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEE-----KI 600
Query: 297 AHRRNMLKGQHEKEAADRKRKQEEQ 321
R L+ EK+ ++ +EE+
Sbjct: 601 EPREPNLEPMVEKQESENSCNKEEE 625
Score = 46.6 bits (109), Expect = 3e-05
Identities = 49/186 (26%), Positives = 84/186 (45%), Gaps = 53/186 (28%)
Query: 144 AARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMV-KQ 202
A R RKR+ E++ EE R AA K+ + + ++ KQ
Sbjct: 458 AVERARKRREEEERRMEEQ-------------------RKAACAEKLKRLDEKLGILEKQ 498
Query: 203 PCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRK 262
P P E I E ++ K++ + EK+ +K+ +++ E ++E+D+ R++ +KE +KE E +R
Sbjct: 499 PSPEE---IREREREKER-EREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQR- 553
Query: 263 NLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRK-QEEQ 321
E EK+RK + L+ Q EKE +K K QE++
Sbjct: 554 --------------------EMEKERK-------QEKEKELERQKEKEKELQKMKEQEKE 586
Query: 322 METEHQ 327
E E +
Sbjct: 587 CELEKE 592
Score = 38.1 bits (87), Expect = 0.011
Identities = 49/211 (23%), Positives = 88/211 (41%), Gaps = 26/211 (12%)
Query: 83 EIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDT-DHEEKASNEDVT-KAVDIT 140
+++ +PK F + SS+ +V+ K S S ED H A+N+ +A D
Sbjct: 853 QLEAHPKADFIRE---------SSEAQVQ-KFLSRSVEDVRPHHTDANNQSACFEAPDQK 902
Query: 141 TPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMV 200
T A + R E Q + + + ++ K +R P+A G PK+
Sbjct: 903 TLSAPQEERISAVESQPSRKRS---VSHGSNHTQKPDEQRSEPSA---------GIPKVT 950
Query: 201 KQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEED-KPRKEPDKKEGKKEVES 259
+ S+ I E+K KK+G +P+K + + E PR +++E +
Sbjct: 951 SRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPV 1010
Query: 260 KRKN-LAKTGVTSTSDSEEEGDDQEGEKKRK 289
+R + K + + E+ ++EGEK K
Sbjct: 1011 RRSGPIKKPVLRDMKEEREQRKEKEGEKAEK 1041
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 54.3 bits (129), Expect = 1e-07
Identities = 34/125 (27%), Positives = 68/125 (54%), Gaps = 6/125 (4%)
Query: 213 EEDKSKKKGQEEKQPKKQPKKDEEGQ---KEEDKPRKEPDKKEGKKEVESKRKNLAKTGV 269
E+++ +++G++EK+ +K+ ++ +E + KE +K RKE +KE +K + K+K K
Sbjct: 51 EKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRG 110
Query: 270 TSTSDSEEEGDDQEGEKKRKGGRNFQTAH---RRNMLKGQHEKEAADRKRKQEEQMETEH 326
++E ++E E K++ R + RR K + E+ +RKRK+ ++ E E
Sbjct: 111 RRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREK 170
Query: 327 QTTCN 331
+ N
Sbjct: 171 KRERN 175
Score = 53.9 bits (128), Expect = 2e-07
Identities = 52/240 (21%), Positives = 102/240 (42%), Gaps = 27/240 (11%)
Query: 90 VKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGR 149
VK S +AA K + V +SK T E + E + R R
Sbjct: 2 VKAISSRAAVKLNTELQMVSCSH----ISKPCTQRESERKKE-----------RREREKR 46
Query: 150 KRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESD 209
KR+ EK+ + E K KR + + + K + R K K+ E
Sbjct: 47 KREREKERKRERGK-----------KEKKKRKKRERGKERERKRKEREKQRKERREKERR 95
Query: 210 IITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGV 269
+E K +++ Q ++ +K+ K+ +E ++E + R+ KK KK+ +RK + G
Sbjct: 96 KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGK 155
Query: 270 TSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQ-EEQMETEHQT 328
+ + +++E +++R + R+ + + E++ RK+K+ ++ +T+ QT
Sbjct: 156 RERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQT 215
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.124 0.344
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,360,358
Number of Sequences: 37866
Number of extensions: 804367
Number of successful extensions: 19254
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 681
Number of HSP's successfully gapped in prelim test: 872
Number of HSP's that attempted gapping in prelim test: 5755
Number of HSP's gapped (non-prelim): 6616
length of query: 333
length of database: 18,247,518
effective HSP length: 103
effective length of query: 230
effective length of database: 14,347,320
effective search space: 3299883600
effective search space used: 3299883600
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.