BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|189181750 human immunodeficiency virus type I enhancer binding protein 3 b [Homo sapiens] (2405 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|189181750 human immunodeficiency virus type I enhancer bindin... 4893 0.0 gi|116089331 human immunodeficiency virus type I enhancer bindin... 4888 0.0 gi|110347463 human immunodeficiency virus type I enhancer bindin... 1042 0.0 gi|116805342 human immunodeficiency virus type I enhancer bindin... 721 0.0 gi|123701326 zinc finger protein 831 [Homo sapiens] 171 1e-41 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 106 2e-22 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 88 9e-17 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 86 4e-16 gi|163965366 nascent polypeptide-associated complex alpha subuni... 80 2e-14 gi|49087132 sal-like 2 [Homo sapiens] 79 7e-14 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 75 6e-13 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 74 2e-12 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 74 2e-12 gi|154146199 sal-like 3 [Homo sapiens] 73 4e-12 gi|150170670 piccolo isoform 2 [Homo sapiens] 71 1e-11 gi|150378539 piccolo isoform 1 [Homo sapiens] 71 1e-11 gi|189217876 sal-like 1 isoform b [Homo sapiens] 71 1e-11 gi|118442837 sal-like 1 isoform a [Homo sapiens] 71 1e-11 gi|40807465 zinc finger protein 341 [Homo sapiens] 71 1e-11 gi|221139761 zinc finger protein 853 [Homo sapiens] 69 4e-11 gi|193082982 zinc finger protein 837 isoform 1 [Homo sapiens] 69 6e-11 gi|193082980 zinc finger protein 837 isoform 2 [Homo sapiens] 69 6e-11 gi|4508009 zinc finger protein 177 [Homo sapiens] 69 7e-11 gi|138175817 zinc finger protein 236 [Homo sapiens] 68 1e-10 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 67 2e-10 gi|10047144 sal-like 4 [Homo sapiens] 67 2e-10 gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 67 2e-10 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 67 2e-10 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 67 2e-10 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 67 2e-10 >gi|189181750 human immunodeficiency virus type I enhancer binding protein 3 b [Homo sapiens] Length = 2405 Score = 4893 bits (12691), Expect = 0.0 Identities = 2405/2405 (100%), Positives = 2405/2405 (100%) Query: 1 MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFP 60 MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFP Sbjct: 1 MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFP 60 Query: 61 GPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQ 120 GPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQ Sbjct: 61 GPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQ 120 Query: 121 LVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAH 180 LVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAH Sbjct: 121 LVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAH 180 Query: 181 KKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRK 240 KKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRK Sbjct: 181 KKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRK 240 Query: 241 SHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSP 300 SHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSP Sbjct: 241 SHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSP 300 Query: 301 RPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTI 360 RPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTI Sbjct: 301 RPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTI 360 Query: 361 KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFG 420 KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFG Sbjct: 361 KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFG 420 Query: 421 KCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSE 480 KCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSE Sbjct: 421 KCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSE 480 Query: 481 IDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRS 540 IDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRS Sbjct: 481 IDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRS 540 Query: 541 HSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGE 600 HSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGE Sbjct: 541 HSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGE 600 Query: 601 YSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEA 660 YSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEA Sbjct: 601 YSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEA 660 Query: 661 HKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKS 720 HKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKS Sbjct: 661 HKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKS 720 Query: 721 LGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKP 780 LGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKP Sbjct: 721 LGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKP 780 Query: 781 GSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSA 840 GSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSA Sbjct: 781 GSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSA 840 Query: 841 HSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEK 900 HSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEK Sbjct: 841 HSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEK 900 Query: 901 LPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAP 960 LPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAP Sbjct: 901 LPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAP 960 Query: 961 SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSL 1020 SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSL Sbjct: 961 SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSL 1020 Query: 1021 TGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS 1080 TGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS Sbjct: 1021 TGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS 1080 Query: 1081 AKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLP 1140 AKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLP Sbjct: 1081 AKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLP 1140 Query: 1141 PPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHP 1200 PPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHP Sbjct: 1141 PPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHP 1200 Query: 1201 GQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQ 1260 GQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQ Sbjct: 1201 GQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQ 1260 Query: 1261 IKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVP 1320 IKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVP Sbjct: 1261 IKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVP 1320 Query: 1321 VRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGP 1380 VRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGP Sbjct: 1321 VRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGP 1380 Query: 1381 SGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLEL 1440 SGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLEL Sbjct: 1381 SGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLEL 1440 Query: 1441 TMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLS 1500 TMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLS Sbjct: 1441 TMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLS 1500 Query: 1501 SLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQP 1560 SLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQP Sbjct: 1501 SLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQP 1560 Query: 1561 DLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHA 1620 DLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHA Sbjct: 1561 DLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHA 1620 Query: 1621 DRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSS 1680 DRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSS Sbjct: 1621 DRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSS 1680 Query: 1681 RKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSN 1740 RKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSN Sbjct: 1681 RKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSN 1740 Query: 1741 EEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800 EEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH Sbjct: 1741 EEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800 Query: 1801 MKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLD 1860 MKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLD Sbjct: 1801 MKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLD 1860 Query: 1861 EDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSE 1920 EDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSE Sbjct: 1861 EDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSE 1920 Query: 1921 AERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPP 1980 AERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPP Sbjct: 1921 AERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPP 1980 Query: 1981 LARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCP 2040 LARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCP Sbjct: 1981 LARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCP 2040 Query: 2041 LGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAG 2100 LGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAG Sbjct: 2041 LGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAG 2100 Query: 2101 EHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSAL 2160 EHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSAL Sbjct: 2101 EHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSAL 2160 Query: 2161 HDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAW 2220 HDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAW Sbjct: 2161 HDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAW 2220 Query: 2221 VSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERT 2280 VSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERT Sbjct: 2221 VSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERT 2280 Query: 2281 GGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNP 2340 GGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNP Sbjct: 2281 GGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNP 2340 Query: 2341 EPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDR 2400 EPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDR Sbjct: 2341 EPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDR 2400 Query: 2401 VPPNA 2405 VPPNA Sbjct: 2401 VPPNA 2405 >gi|116089331 human immunodeficiency virus type I enhancer binding protein 3 [Homo sapiens] Length = 2406 Score = 4888 bits (12679), Expect = 0.0 Identities = 2405/2406 (99%), Positives = 2405/2406 (99%), Gaps = 1/2406 (0%) Query: 1 MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFP 60 MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFP Sbjct: 1 MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFP 60 Query: 61 GPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQ 120 GPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQ Sbjct: 61 GPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQ 120 Query: 121 LVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAH 180 LVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAH Sbjct: 121 LVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAH 180 Query: 181 KKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRK 240 KKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRK Sbjct: 181 KKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRK 240 Query: 241 SHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSP 300 SHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSP Sbjct: 241 SHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSP 300 Query: 301 RPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTI 360 RPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTI Sbjct: 301 RPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTI 360 Query: 361 KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFG 420 KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFG Sbjct: 361 KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFG 420 Query: 421 KCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSE 480 KCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSE Sbjct: 421 KCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSE 480 Query: 481 IDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRS 540 IDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRS Sbjct: 481 IDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRS 540 Query: 541 HSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGE 600 HSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGE Sbjct: 541 HSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGE 600 Query: 601 YSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEA 660 YSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEA Sbjct: 601 YSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEA 660 Query: 661 HKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKS 720 HKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKS Sbjct: 661 HKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKS 720 Query: 721 LGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKP 780 LGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKP Sbjct: 721 LGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKP 780 Query: 781 GSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSA 840 GSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSA Sbjct: 781 GSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSA 840 Query: 841 HSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEK 900 HSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEK Sbjct: 841 HSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEK 900 Query: 901 LPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAP 960 LPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAP Sbjct: 901 LPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAP 960 Query: 961 SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSL 1020 SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSL Sbjct: 961 SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSL 1020 Query: 1021 TGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS 1080 TGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS Sbjct: 1021 TGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS 1080 Query: 1081 AKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLP 1140 AKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLP Sbjct: 1081 AKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLP 1140 Query: 1141 PPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHP 1200 PPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHP Sbjct: 1141 PPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHP 1200 Query: 1201 GQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQ 1260 GQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQ Sbjct: 1201 GQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQ 1260 Query: 1261 IKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVP 1320 IKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVP Sbjct: 1261 IKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVP 1320 Query: 1321 VRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGP 1380 VRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGP Sbjct: 1321 VRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGP 1380 Query: 1381 SGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLEL 1440 SGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLEL Sbjct: 1381 SGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLEL 1440 Query: 1441 TMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLS 1500 TMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLS Sbjct: 1441 TMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLS 1500 Query: 1501 SLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQP 1560 SLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQP Sbjct: 1501 SLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQP 1560 Query: 1561 DLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHA 1620 DLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHA Sbjct: 1561 DLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHA 1620 Query: 1621 DRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSS 1680 DRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSS Sbjct: 1621 DRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSS 1680 Query: 1681 RKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSN 1740 RKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSN Sbjct: 1681 RKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSN 1740 Query: 1741 EEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800 EEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH Sbjct: 1741 EEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800 Query: 1801 MKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLD 1860 MKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLD Sbjct: 1801 MKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLD 1860 Query: 1861 EDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSE 1920 EDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSE Sbjct: 1861 EDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSE 1920 Query: 1921 AERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPP 1980 AERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPP Sbjct: 1921 AERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPP 1980 Query: 1981 LARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCP 2040 LARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCP Sbjct: 1981 LARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCP 2040 Query: 2041 LGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAG 2100 LGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAG Sbjct: 2041 LGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAG 2100 Query: 2101 EHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPW-KAESRSPSCSPGPAHPLSSRPFSA 2159 EHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPW KAESRSPSCSPGPAHPLSSRPFSA Sbjct: 2101 EHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQKAESRSPSCSPGPAHPLSSRPFSA 2160 Query: 2160 LHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAA 2219 LHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAA Sbjct: 2161 LHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAA 2220 Query: 2220 WVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERER 2279 WVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERER Sbjct: 2221 WVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERER 2280 Query: 2280 TGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTN 2339 TGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTN Sbjct: 2281 TGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTN 2340 Query: 2340 PEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPED 2399 PEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPED Sbjct: 2341 PEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPED 2400 Query: 2400 RVPPNA 2405 RVPPNA Sbjct: 2401 RVPPNA 2406 >gi|110347463 human immunodeficiency virus type I enhancer binding protein 2 [Homo sapiens] Length = 2446 Score = 1042 bits (2695), Expect = 0.0 Identities = 864/2362 (36%), Positives = 1132/2362 (47%), Gaps = 367/2362 (15%) Query: 52 ELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPE 111 +L PS V+++ ++Q PP RP + H PQH L M KP Sbjct: 62 QLFGSGKLASPSEVVQQ-----VAEKQYPPHRPSPYSCQHSLSFPQHSLPQGVMHSTKPH 116 Query: 112 HLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQV 171 LEG W + PGP S + L P + H+ P + + + + + SQ Sbjct: 117 QSLEGPPW-----LFPGPLPSVASEDLFPFP--IHGHSGGYPRKKISSLNPAY-SQYSQK 168 Query: 172 SLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKT 231 S++ EEAHKKE KP+KPGKYIC YCSR CAKPSVL+KHIRSHTGERPYPC PCGFSFKT Sbjct: 169 SIEQAEEAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKT 228 Query: 232 KSNLYKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSAT 291 KSNLYKHRKSHAH IKAGL + LE I E +STD++EE+S Sbjct: 229 KSNLYKHRKSHAHAIKAGLVPFTESAVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLF 288 Query: 292 SGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPP---PFVEPSSEH 348 + ++SP P PL + S G + S E SL L P P SS++ Sbjct: 289 AEASDKMSPGPPIPL---DIASRGGYHGSLEE-SLGGPMKVPILIIPKSGIPLPNESSQY 344 Query: 349 ---------PLSHKPEDTHTIKQKLALRLSERKKVIDEQAF--LSPGSKGSTESGYFSRS 397 L+ K +D+HT+KQKLALRLSE+K E + LSP SKGST+SGYFSRS Sbjct: 345 IGPDMLPNPSLNTKADDSHTVKQKLALRLSEKKGQDSEPSLNLLSPHSKGSTDSGYFSRS 404 Query: 398 ESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVP 457 ESAEQQ+SPPNTNAKSY EIIFGK R+ R A+ T++Q + + +P Sbjct: 405 ESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNALSVTTTSQERAAMGRKGIMEPLPHVNT 464 Query: 458 RTQV--IEHITKLITINEAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLYREPL-SSHSE 514 R V E + ++ VD S+ +K + + R P S L ++ + Sbjct: 465 RLDVKMFEDPVSQLIPSKGDVDPSQTSMLKSTKFNSESRQPQIIPSSIRNEGKLYPANFQ 524 Query: 515 KTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALS 574 + P + L+ P ++P L+RS+S+P+++ T T RGS+SFD+ +T S+ + Sbjct: 525 GSNP----VLLEAPVDSSP---LIRSNSVPTSSATNLTIPPSLRGSHSFDERMTGSDDVF 577 Query: 575 HSSHVFTSHPRMLKRQPAIELPL--GGEYSSEEPGPSSKDTASKPSDEVEPKESELTKKT 632 + V RML+RQ A ELP G E G K +S KE +L+ Sbjct: 578 YPGTVGIPPQRMLRRQAAFELPSVQEGHVEVEHHGRMLKGISSSSL-----KEKKLSPGD 632 Query: 633 KKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEH 692 + G Y+ ++C YKK ++ E K+ Y + IS + E Sbjct: 633 RVG-------YDYDVCRKPYKKWEDSETPKQNY-------RDISCLSSLKHGGEYFMDPV 678 Query: 693 EPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAF---------------------- 730 P Q + GTT E RKRRKEKS+GDEE+ P Sbjct: 679 VPL-QGVPSMFGTTCEN---RKRRKEKSVGDEEDTPMICSSIVSTPVGIMASDYDPKLQM 734 Query: 731 -ESTKSQFGSPGPSDAA-----RNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGS 784 E +S F G + + R P P PS + S E P+ G Sbjct: 735 QEGVRSGFAMAGHENLSHGHTERFDPCRPQLQPGSPS--LVSEESPSAIDSDKMSDLGG- 791 Query: 785 ESGKERRTTSKEISVIQHTSS------FEKSDSLE--------QPSGLEGEDKPLAQFP- 829 R+ ISVIQHT+S FE+S+S E PS E D +++ P Sbjct: 792 -----RKPPGNVISVIQHTNSLSRPNSFERSESAELVACTQDKAPSPSETCDSEISEAPV 846 Query: 830 SPPPAPHGRSAHS----------------LQPKLVRQPNIQVPEILVTEEPDRPDTEPEP 873 SP AP G A S QP+LVRQ NIQVPEI VTEEPD+P+ E E Sbjct: 847 SPEWAPPGDGAESGGKPSPSQQVQQQSYHTQPRLVRQHNIQVPEIRVTEEPDKPEKEKEA 906 Query: 874 PPKEPEK-TEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESS-VPLSRS 931 KEPEK EEFQWPQRS+TL+QLPAEKLPPKKKRLRLA+M SSGESSFES+ LSRS Sbjct: 907 QSKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTGTGLSRS 966 Query: 932 PSQESNVSLSGSSRSASFERDDHGKAEAPSPS------SDMRPKPLGTHMLTVPSHHPHA 985 PSQESN+S S SS S SFER++ K A S+ P G++ L+VP HH H Sbjct: 967 PSQESNLSHS-SSFSMSFEREETSKLSALPKQDEFGKHSEFLTVPAGSYSLSVPGHH-HQ 1024 Query: 986 REMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPP-ERRKCF 1044 +EMRR +SEQ P H A + E RSKSFDYG+LS AP A + V+P ER+KCF Sbjct: 1025 KEMRRCSSEQMP-CPHPAEVPEVRSKSFDYGNLS----HAPVSGAAASTVSPSRERKKCF 1079 Query: 1045 LVRQASLSRPPE-SELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATS--HGGPPGG 1101 LVRQAS S PE S+ EV + E+ L + + S H GPP Sbjct: 1080 LVRQASFSGSPEISQGEVGMDQSVKQEQ-------------LEHLHAGLRSGWHHGPPAV 1126 Query: 1102 KGPGQDRPP----LGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPG 1157 P Q P GP P + PLH L P H+ E Sbjct: 1127 LPPLQQEDPGKQVAGPCPPLSSG-----------PLH----LAQP----QIMHMDSQESL 1167 Query: 1158 QSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPF 1217 ++P T M+S +P P +P P Q P + ++P Sbjct: 1168 RNPLIQPTSYMTSK-----HLPEQPHLFPHQETIPFSPIQNALFQFQYPTVCM--VHLPA 1220 Query: 1218 RQPP---SFLPMPY---PTSSALSSGFFLPLQSQFALQLPGDVESHLP----QIKTSLAP 1267 +QPP + P P+ P S F + S + L+ + P K P Sbjct: 1221 QQPPWWQAHFPHPFAQHPQKSYGKPSFQTEIHSSYPLEHVAEHTGKKPAEYAHTKEQTYP 1280 Query: 1268 LATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPP---------LALPACPDTMVSLV 1318 +G++GL P L P P SS T P A ++ V Sbjct: 1281 CYSGASGLHPKN-------LLPKFPSDQSSKSTETPSEQVLQEDFASANAGSLQSLPGTV 1333 Query: 1319 VPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGP 1378 VPVR+QT++PSYGS MYT++SQIL Q S A V + K +E ++ T V A + +G Sbjct: 1334 VPVRIQTHVPSYGSVMYTSISQIL---GQNSPAIV-ICKVDENMTQRTLVTNAAMQGIGF 1389 Query: 1379 GPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSL 1438 + + + + P + P TLP +S+ + S S +T GGSKR+LSPA SL Sbjct: 1390 NIAQVLGQHAGLEKYPIWKAPQTLPLGLESSIPL-CLPSTSDSVATLGGSKRMLSPASSL 1448 Query: 1439 ELTMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGK----RPEKSHLGNQGQGRR 1494 EL MET+QQKRVKEE+ ++V+ S V + D K RP+K L QG Sbjct: 1449 ELFMETKQQKRVKEEKMYG-----QIVEELSAVELTNSDIKKDLSRPQKPQLVRQGCASE 1503 Query: 1495 ELEMLSSLSSD-----PSDTKEIPPLPHPALSHGTAPGSEALK--EYPQPSGKPHRRGLT 1547 + L S SS PS +++ P + P+ P E L P P K + Sbjct: 1504 PKDGLQSGSSSFSSLSPSSSQDYPSVS-PSSREPFLPSKEMLSGSRAPLPGQKSSGPSES 1562 Query: 1548 PLSVKKEDSKEQPDLPSLAPPSS-LPLSETSS---------------RPAKSQEGT---- 1587 S + D E S++P SS LP + R A + G Sbjct: 1563 KESSDELDIDETASDMSMSPQSSSLPAGDGQLEEEGKGHKRPVGMLVRMASAPSGNVADS 1622 Query: 1588 --------DSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNL 1639 D +++LQFPSL TTT VSWC+LNY KPN++Q A +SSVYA WCIS NPN Sbjct: 1623 TLLLTDMADFQQILQFPSLRTTTTVSWCFLNYTKPNYVQQATFKSSVYASWCISSCNPNP 1682 Query: 1640 PGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPS--LVSPE 1697 G++TK L+LLRSKQK++ E YT+A P G+L SS+ K + T++ + L + Sbjct: 1683 SGLNTKTTLALLRSKQKITAEIYTLAAMHRPGTGKLTSSSAWK-QFTQMKPDASFLFGSK 1741 Query: 1698 GQKDLARVEKEEERRGEPEEDAP-ASQRGEPARIKIFEGGYKSNEEYVYVRGRGRGKYVC 1756 ++ L +E +G+ D S++ EP RIKIFEGGYKSNE+YVYVRGRGRGKY+C Sbjct: 1742 LERKLVGNILKERGKGDIHGDKDIGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYIC 1801 Query: 1757 EECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQETGV- 1815 EECGIRCKKPSMLKKHIRTHTDVRPYVCK C+FAFKTKGNLTKHMKSKAH KKC E GV Sbjct: 1802 EECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVS 1861 Query: 1816 ---LEELEAEEGTS-DDLFQDSEGREGSEAVEEHQFSDLEDSDS---DSDLDEDEDEDEE 1868 +++ E EE + +DL + +E S +HQFSD E+SD D + D+DEDED+ Sbjct: 1862 MTSVDDTETEEAENLEDLHKAAEKHSMSSISTDHQFSDAEESDGEDGDDNDDDDEDEDDF 1921 Query: 1869 ESQDELS-RPSSEAPPPGPPHALRADSSPI-LGPQPPDAPASG----------------- 1909 + Q +L+ + S + P PP R S P+ +G P P+ Sbjct: 1922 DDQGDLTPKTRSRSTSPQPP---RFSSLPVNVGAVPHGVPSDSSLGHSSLISYLVTLPSI 1978 Query: 1910 --TEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRR 1967 T+ S E ++T S+S P + S D L +P S R Sbjct: 1979 RVTQLMTPSDSCEDTQMTEYQRLFQSKSTDSEPDKDRLDIPSC-MDEECMLPSEPSSSPR 2037 Query: 1968 PWSPSKEAGSRPPLARKHSLTKNDSSPQRC-SPAREPQASAPSPPGLHVDPGRGMGALPC 2026 +SPS HS DSSP R SP R P H+ P R + Sbjct: 2038 DFSPSSH----------HSSPGYDSSPCRDNSPKRYLIPKGDLSPRRHLSPRRDL----- 2082 Query: 2027 GSPRLQLSPLTLCPLGRELA-----PRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPP 2081 SP LSP L RE++ PR H+ SP R SPG+ + Sbjct: 2083 -SPMRHLSPRKEAALRREMSQRDVSPRRHL---------------SPRRPVSPGKDITAR 2126 Query: 2082 RSAPPGK-----WALAGPGSPSAGEHGPGLGLDPRVLFPPAPL-PHKLLSRSPETCASPW 2135 R P + + P A H P L + + P L P L P+ Sbjct: 2127 RDLSPRRERRYMTTIRAPSPRRALYHNPPLSMGQYLQAEPIVLGPPNLRRGLPQVPYFSL 2186 Query: 2136 KAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIP 2195 + HP SS +D+ +FSHLPLHSQ RAP P++P Sbjct: 2187 YGDQEGAY-----EHPGSSLFPEGPNDY-----------VFSHLPLHSQQQVRAPIPMVP 2230 Query: 2196 IGGIQMVQARPGAHPTLLPGPT 2217 +GGIQMV + P A +L P PT Sbjct: 2231 VGGIQMVHSMPPALSSLHPSPT 2252 >gi|116805342 human immunodeficiency virus type I enhancer binding protein 1 [Homo sapiens] Length = 2718 Score = 721 bits (1861), Expect = 0.0 Identities = 685/2116 (32%), Positives = 940/2116 (44%), Gaps = 369/2116 (17%) Query: 182 KERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKS 241 K++KP+K GKYIC+YC+R CAKPSVL KHIRSHTGERPYPC CGFSFKTKSNLYKH+KS Sbjct: 396 KDQKPKKQGKYICEYCNRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKS 455 Query: 242 HAHRIKAGLA--SGMGGEMYPH----GLEMERIPGEEFEEPTEGESTDSEEETSATSGHP 295 HAH IK GL GG H L + + E EG + + + + A P Sbjct: 456 HAHTIKLGLVLQPDAGGLFLSHESPKALSIHSDVEDSGESEEEGATDERQHDLGAMELQP 515 Query: 296 AELSPRPK--QPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFV---------EP 344 + R + LL S S + + +S+ +Q++ + P V Sbjct: 516 VHIIKRMSNAETLLKSSFTPSSPENVIGDFLLQDRSAESQAVTELPKVVVHHVTVSPLRT 575 Query: 345 SSEHPLSHKPEDTHTIKQK---------LALRLSE------------------------- 370 S + KPE + KQK L+ +S+ Sbjct: 576 DSPKAMDPKPELSSAQKQKDLQVTNVQPLSANMSQGGVSRLETNENSHQKGDMNPLEGKQ 635 Query: 371 ------------RKKVID-----EQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKS 413 R++ D + LSP S GST+SGYFSRSESA+Q VSPP A+ Sbjct: 636 DSHVGTVHAQLQRQQATDYSQEQQGKLLSPRSLGSTDSGYFSRSESADQTVSPPTPFARR 695 Query: 414 YAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVP---RTQVIEH-ITKLI 469 GR +A L TST LP T +K L+P + T+ +E I+KLI Sbjct: 696 LPSTEQDS-GRSNGPSAALVTTSTPSALP--TGEKALLLPGQMRPPLATKTLEERISKLI 752 Query: 470 TINEAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLYREPL-----------SSHSE---- 514 + NEA+VD ++DSVKPRR+SLSRR S++SPKS ++++ SS S+ Sbjct: 753 SDNEALVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPVGRRTSSSSDIPKS 812 Query: 515 ---KTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAA-----CTISTPHHPFRGSYSFDDH 566 T+ + + L P + +P+ RS+SMP+ I P HP RGS SFDD Sbjct: 813 PFTPTEKSKQVFLLSVP--SLDCLPITRSNSMPTTGYSAVPANIIPPPHPLRGSQSFDDK 870 Query: 567 I---TDSEALS--HSSHVFTSHPRMLKRQPAIELPLGGEYSSEEPGPS---SKDTASKPS 618 I D +S ++ + HPR L RQ AIE E G S S Sbjct: 871 IGTFYDDVFVSGPNAPVPQSGHPRTLVRQAAIEDSSANESHVLGTGQSLDESHQGCHAAG 930 Query: 619 DEVEPKESELTK----KTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKP 674 + + + L + + KK + +G ++EC C RY+K +N+E HKK+YCSEL K Sbjct: 931 EAMSVRSKALAQGPHIEKKKSHQGRGTMFECETCRNRYRKLENFENHKKFYCSELHGPKT 990 Query: 675 ISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTT---LELTP-LRKRRKEKSLGDEEEPPAF 730 A E E S + Q++HY++ + E TP +RKRRK KS+GD+EE Sbjct: 991 KVA----MREPEHSPVPGGLQPQILHYRVAGSSGIWEQTPQIRKRRKMKSVGDDEELQQN 1046 Query: 731 ESTKSQFGSPG----------PSDAARNLPLESTKS----PAEPSKSVPSLEGPTGFQPR 776 ES S S G PS N+ + S + + S GP Q Sbjct: 1047 ESGTSPKSSEGLQFQNALGCNPSLPKHNVTIRSDQQHKNIQLQNSHIHLVARGPE--QTM 1104 Query: 777 TPK--------PGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPS------------ 816 PK S ++ E + ISVIQHT+S + +S ++P Sbjct: 1105 DPKLSTIMEQQISSAAQDKIELQRHGTGISVIQHTNSLSRPNSFDKPEPFERASPVSFQE 1164 Query: 817 -------------GLEGEDKPLAQFPSPP------------------PAPHGRSAHSLQP 845 G+ E+ ++ S P +P R Sbjct: 1165 LNRTGKSGSLKVIGISQEESHPSRDGSHPHQLALSDALRGELQESSRKSPSERHVLGQPS 1224 Query: 846 KLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKK 905 +LVRQ NIQVPEILVTEEPDR + E + EK+E+F WPQRS+TL++LP EKLPPKK Sbjct: 1225 RLVRQHNIQVPEILVTEEPDR---DLEAQCHDQEKSEKFSWPQRSETLSKLPTEKLPPKK 1281 Query: 906 KRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSD 965 KRLRLAE+ SS ESSF+S+ LSRS S+ES++S + SS SAS + +D K EA SP D Sbjct: 1282 KRLRLAEIEHSSTESSFDST--LSRSLSRESSLSHT-SSFSASLDIEDVSKTEA-SPKID 1337 Query: 966 MRPK------PLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLS 1019 K P G + L VP H REMRR+ASEQ S +++ RSKSFD GS++ Sbjct: 1338 FLNKAEFLMIPAGLNTLNVPGCH---REMRRTASEQINCTQTSMEVSDLRSKSFDCGSIT 1394 Query: 1020 ---------LTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELE-VAPKGRQES 1069 L PS+P+ V V ERR+ LVRQ SL+ P+S L V P Q + Sbjct: 1395 PPQTTPLTELQPPSSPSRVGVTGHVPLLERRRGPLVRQISLNIAPDSHLSPVHPTSFQNT 1454 Query: 1070 EEPQ----PSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFH 1125 P P +SL++ SA T H L + + VF Sbjct: 1455 ALPSVNAVPYQGPQLTSTSLAEF-SANTLHS--------QTQVKDLQAETSNSSSTNVF- 1504 Query: 1126 HPVAQ---TPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLP 1182 PV Q L + + PP H+ Q STQ +S S Sbjct: 1505 -PVQQLCDINLLNQIHAPP-----------SHQSTQLSLQVSTQGSKPDKNSVLSGSSKS 1552 Query: 1183 PSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPL 1242 F AP L V G P +P + P + P T ++S Sbjct: 1553 EDCF-APKYQLHCQVFTSG----PSCSSNPVH---SLPNQVISDPVGTDHCVTS------ 1598 Query: 1243 QSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSA 1302 + +L + + P + L PL GS + + IRL P + TS Sbjct: 1599 -ATLPTKLIDSMSNSHPLLPPELRPL--GSQVQKVPSSFMLPIRLQSSVPAYCFATLTSL 1655 Query: 1303 PPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPP 1362 P + +V+ +P N P T S + +++ Q S T+ P Sbjct: 1656 PQI--------LVTQDLP-----NQP----ICQTNHSVVPISEEQNSVPTLQKGHQNALP 1698 Query: 1363 SKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSS 1422 + +V S LSE +P+T S+ L Sbjct: 1699 NPEKEFLCENVFSEMSQNSSLSES-----------LPIT---------QKISVGRLSPQQ 1738 Query: 1423 STAGGSKRVLSPAGSLELTMETQQQKRVKEEE--------------ASKADEKLELVKPC 1468 ++ SKR+LSPA SL++ ME + QKR K+E +S+ +E + KP Sbjct: 1739 ESSASSKRMLSPANSLDIAME-KHQKRAKDENGAVCATDVRPLEALSSRVNEASKQKKPI 1797 Query: 1469 ---SVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDT--------KEIPPLPH 1517 V T DG EK + + + L +D S T + I L Sbjct: 1798 LVRQVCTTEPLDGVMLEKDVFSQPEISNEAVNLTNVLPADNSSTGCSKFVVIEPISELQE 1857 Query: 1518 PALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLA-PPSSLPLSET 1576 + + ++ P PS H ++PL K D+ ++ P + + + E Sbjct: 1858 FENIKSSTSLTLTVRSSPAPSENTH---ISPL--KCTDNNQERKSPGVKNQGDKVNIQEQ 1912 Query: 1577 SSRPAKSQEGTDSK--KVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISL 1634 S +P S + K + L FPSL TTTN +WCYL K H+ D+++S Y W +S Sbjct: 1913 SQQPVTSLSLFNIKDTQQLAFPSLKTTTNFTWCYLLRQKSLHLPQKDQKTSAYTDWTVSA 1972 Query: 1635 YNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHL---P 1691 NPN G+ TK AL+LL SKQ K Y A H ++ LV SS K +++ L Sbjct: 1973 SNPNPLGLPTKVALALLNSKQNTGKSLYCQAITTHSKSDLLVYSSKWKSSLSKRALGNQK 2032 Query: 1692 SLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSNEEYVYVRGRGR 1751 S V KD + + E+++ + + EP RIKIF+GGYKSNEEYVYVRGRGR Sbjct: 2033 STVVEFSNKDASEINSEQDKEN-------SLIKSEPRRIKIFDGGYKSNEEYVYVRGRGR 2085 Query: 1752 GKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQ 1811 GKY+CEECGIRCKKPSMLKKHIRTHTDVRPY C +C+F+FKTKGNLTKHMKSKAHSKKC Sbjct: 2086 GKYICEECGIRCKKPSMLKKHIRTHTDVRPYHCTYCNFSFKTKGNLTKHMKSKAHSKKCV 2145 Query: 1812 ETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQ 1871 + GV L E+ T E E E DLE+SD + D + ++D+E+SQ Sbjct: 2146 DLGVSVGLIDEQDT-------EESDEKQRFSYERSGYDLEESDGPDEDDNENEDDDEDSQ 2198 Query: 1872 DELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAE--------R 1923 E ++ + P H S + P D T+ G + R Sbjct: 2199 AESVLSATPSVTASPQHL--PSRSSLQDPVSTDEDVRITDCFSGVHTDPMDVLPRALLTR 2256 Query: 1924 LTASSCSMSSQSMPGL-PWLGPAPLGSVEKDTGSAL--SYKPVSPRRPWSPSKEAGSRPP 1980 +T S + S + L P E DT ++ S P P E R Sbjct: 2257 MTVLSTAQSDYNRKTLSPGKARQRAARDENDTIPSVDTSRSPCHQMSVDYPESEEILRSS 2316 Query: 1981 LARKH-SLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLC 2039 +A K ++T++ SS R P A+A P G A P P+ Q +TL Sbjct: 2317 MAGKAVAITQSPSS------VRLPPAAAEHSP--QTAAGMPSVASPHPDPQEQKQQITLQ 2368 Query: 2040 PLGRELAPRAHVLSKL 2055 P +P H+ S L Sbjct: 2369 PTPGLPSPHTHLFSHL 2384 Score = 48.5 bits (114), Expect = 8e-05 Identities = 46/140 (32%), Positives = 60/140 (42%), Gaps = 29/140 (20%) Query: 2067 SPTRRWSPGQAESPP--RSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLL 2124 SP + S ES RS+ GK A+A SPS+ V PPA H Sbjct: 2297 SPCHQMSVDYPESEEILRSSMAGK-AVAITQSPSS------------VRLPPAAAEH--- 2340 Query: 2125 SRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQ 2184 SP+T A S P ++ +P L H H+ FSHLPLHSQ Sbjct: 2341 --SPQTAAGMPSVASPHPDPQE-QKQQITLQPTPGLPSPHTHL--------FSHLPLHSQ 2389 Query: 2185 HLTRAPCPLIPIGGIQMVQA 2204 +R P ++P+GGI +V A Sbjct: 2390 QQSRTPYNMVPVGGIHVVPA 2409 >gi|123701326 zinc finger protein 831 [Homo sapiens] Length = 1677 Score = 171 bits (432), Expect = 1e-41 Identities = 272/1136 (23%), Positives = 424/1136 (37%), Gaps = 225/1136 (19%) Query: 49 PAQELLAPQPFPGPSSVLREGSQEKT-GQQQKPPKRPPIEASVHISQLP---QHPLTPAF 104 PA++ AP P P P + + S T G PP++ +V + LP H + P Sbjct: 12 PARDQPAPTPGP-PGAPGGQASPHLTLGPVLLPPEQGLAPPTVFLKALPIPLYHTVPPGG 70 Query: 105 MSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPE------DLP 158 + P P L+ GS + G ++P L P+ P + P ++ Sbjct: 71 LQPRAP--LVTGS-------LDGGNVPFILSPVLQPEG---PGPTQVGKPAAPTLTVNIV 118 Query: 159 GVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGER 218 G V P L PT + K R GKY+C +C R C KPSVL+KHIRSHTGER Sbjct: 119 GTLPVLSP-----GLGPTLGSPGKVRNA---GKYLCPHCGRDCLKPSVLEKHIRSHTGER 170 Query: 219 PYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLAS---GMGGEMYPHGLEMERIPGEEFEE 275 P+PC CG +FKT+SNLYKHR++ H + L+S G GG + G + GE Sbjct: 171 PFPCATCGIAFKTQSNLYKHRRTQTHLNNSRLSSESEGAGGGLLEEGDK----AGEPPRP 226 Query: 276 PTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSL 335 GES A+ LSP PLL+ L + C S + ++ Sbjct: 227 EGRGESRCQGMHEGASE---RPLSPGAHVPLLAKNL----DVRTEAAPCPGSAFADREAP 279 Query: 336 EDPPPFVEP----SSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKG---- 387 D P P +S P PE K L ++ E+ + + +G Sbjct: 280 WDSAPMASPGLPAASTQPWRKLPEQKSPTAGK-PCALQRQQATAAEKPWDAKAPEGRLRK 338 Query: 388 --STESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLST 445 ST+SGY SRS+SAEQ +P + S +E G G A Sbjct: 339 CESTDSGYLSRSDSAEQPHAPCSP-LHSLSEHSAESEGEGGPGPGPGVA---------GA 388 Query: 446 EDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLY 505 E L + + ++ E I +LI+ N+AVVD +++D+V+PR++ LS++ S++ P Y Sbjct: 389 EPGAREAGLELEKKRLEERIAQLISHNQAVVDDAQLDNVRPRKTGLSKQGSIDLPTPYTY 448 Query: 506 ----------------REPLSSHSEKTKPEQSLLSLQHP-----PSTAPPVPLLRSHSMP 544 R P S T P++S H +T VP+ RS+S+P Sbjct: 449 KDSFHFDIRALEPGRRRAPGPVRSTWTPPDKSRPLFFHSVPTQLSTTVECVPVTRSNSLP 508 Query: 545 --SAACTISTPHHPFRGSYSFDD----------HITDSEALSHSSHVFTSHPRMLKRQPA 592 + T P P R +S + LS S+ V + HPR L RQ A Sbjct: 509 FVEGSRTWLEPREP-RDPWSRTQKPLSPRPGPARLGCRSGLS-STDVPSGHPRALVRQAA 566 Query: 593 IELPLGGEYSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARY 652 +E + PG D A P+++ + K + + + G CG R Sbjct: 567 VE---------DLPGTPIGD-ALVPAEDTDAKRTAAREAMAGKGRAGG-----RKCGQRR 611 Query: 653 KKRDNYEAHKKYYCSEL-QIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTP 711 K + E + Y +I + + A H Sbjct: 612 LKMFSQEKWQVYGDETFKRIYQKMKASPHGG----------------------------- 642 Query: 712 LRKRRKEKSLGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPT 771 K+ +E +G E F K GS G +P + ++P S + P Sbjct: 643 --KKAREVGMGSGAE-LGFPLQKEAAGSSG------TVPTQDRRTPVHEDISAGATPEPW 693 Query: 772 GFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSP 831 G P + +E K T ++ + S + + L G D P + SP Sbjct: 694 G-NPPALEASLVTEPTKHGETVAR-----RGDSDRPRVEEAVSSPALGGRDSPCSGSRSP 747 Query: 832 PPAPHGRSAHSLQ----PKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEE---- 883 +P+GR Q P ++ +++ P P PD + E + +E Sbjct: 748 LVSPNGRLELGWQMPPAPGPLKGGDVEAP------RPVWPDPKLEGGARGVGDVQETCLW 801 Query: 884 ----FQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVS 939 +WP R +KLP ++K+L++ ++ + P P+Q + Sbjct: 802 AQTVLRWPSRGS-----GEDKLPSERKKLKVEDLHSWKQPEPVSAETP--GGPTQPA--- 851 Query: 940 LSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNV 999 S S ++ D E P S + + E S+ Sbjct: 852 ------SLSSQKQDADPGEVPGGSKESARQ---------------VGEPLESSGASLAAA 890 Query: 1000 SHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQAS------LSR 1053 S + R K+ + P+APAP P+ PP+ + + L R Sbjct: 891 SVALKRVGPRDKA------TPLHPAAPAPAEHPSLATPPQAPRVLSALADNAFSPKYLLR 944 Query: 1054 PPESELEV---APKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQ 1106 P++E + P G + S++ SS P ++S P G PG+ Sbjct: 945 LPQAETPLPLPIPWGPRHSQDSLCSSGWPEERASFVGSGLGTPLSPSPASGPSPGE 1000 Score = 86.3 bits (212), Expect = 3e-16 Identities = 125/471 (26%), Positives = 167/471 (35%), Gaps = 77/471 (16%) Query: 1749 RGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK 1808 R GKY+C CG C KPS+L+KHIR+HT RP+ C C AFKT+ NL KH +++ H Sbjct: 139 RNAGKYLCPHCGRDCLKPSVLEKHIRSHTGERPFPCATCGIAFKTQSNLYKHRRTQTHLN 198 Query: 1809 KCQETGVLEELEA---EEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDE 1865 + + E EEG EGR S H + S+ Sbjct: 199 NSRLSSESEGAGGGLLEEGDKAGEPPRPEGRGESRCQGMH--------EGASERPLSPGA 250 Query: 1866 DEEESQDELSRPSSEAPPPGPPHALRA---DSSPILGPQPPDAPASGTEATRGSSVSEAE 1922 L + AP PG A R DS+P+ P PA+ T+ R + E + Sbjct: 251 HVPLLAKNLDVRTEAAPCPGSAFADREAPWDSAPMAS---PGLPAASTQPWR--KLPEQK 305 Query: 1923 RLTASS-CSMSSQSMPGL--PWLGPAPLGSVEK--DTGSALSYKPVSPRRPWSPSKEAGS 1977 TA C++ Q PW AP G + K T S + S +P +P Sbjct: 306 SPTAGKPCALQRQQATAAEKPWDAKAPEGRLRKCESTDSGYLSRSDSAEQPHAPCS---- 361 Query: 1978 RPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLT 2037 PL HSL+++ + + P P +PG L RL+ Sbjct: 362 --PL---HSLSEHSAE------SEGEGGPGPGPGVAGAEPGAREAGLELEKKRLEERIAQ 410 Query: 2038 LCPLGR---------ELAPRAHVLSKLEGTTDPGLP------------RYSPTRRWSPGQ 2076 L + + PR LSK +G+ D P P RR +PG Sbjct: 411 LISHNQAVVDDAQLDNVRPRKTGLSK-QGSIDLPTPYTYKDSFHFDIRALEPGRRRAPGP 469 Query: 2077 AESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPA----PLPHKLLSRS---PE 2129 S PP K S H L V P LP SR+ P Sbjct: 470 VRS--TWTPPDK-------SRPLFFHSVPTQLSTTVECVPVTRSNSLPFVEGSRTWLEPR 520 Query: 2130 TCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLP 2180 PW + S PGPA S+ GH A + LP Sbjct: 521 EPRDPWSRTQKPLSPRPGPARLGCRSGLSSTDVPSGHPRALVRQAAVEDLP 571 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 106 bits (265), Expect = 2e-22 Identities = 185/729 (25%), Positives = 257/729 (35%), Gaps = 124/729 (17%) Query: 725 EEPPAFESTKSQFGSPGPSDAARNLP-------------LESTKSP-AEPSKSVPSLEGP 770 E P S+ S+ + PS AAR P L S+ +P + P++S PS G Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262 Query: 771 --TGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSD-SLEQPSGLEGEDKPLAQ 827 P PKP G ++ + + T S + PSG + Sbjct: 263 PRAPAHPSQPKP-KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR------ 315 Query: 828 FPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRP---DTEPEPPPKEPEK---- 880 P PPP +A L L P + P L P P T P PP P + Sbjct: 316 -PVPPP---DNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371 Query: 881 --TEEFQWPQRSQTLAQL--------PAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSR 930 T Q P QT+ + P+ + PP L + S G + +++ Sbjct: 372 MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLT 431 Query: 931 SPSQESNVSLSGSSRSASFERDDHGKAEAP-----SPSSDMRPKPLGTHMLTVPSHHP-H 984 +++ SL+ SR AS D +AP SP P + + + + HP Sbjct: 432 MSPRQTQASLTSPSRPASTPPDSP-PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ 490 Query: 985 AREMRRSASEQSPNVSHSAHMTETRSK----SFDYGSLSLTGP--------------SAP 1026 A S S Q+P S ET+S S SLT P +A Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS 550 Query: 1027 APVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLS 1086 AP+ P PP C L PP P+ P P + A L Sbjct: 551 APLTTPHLETPPCPAPC------PLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQ 604 Query: 1087 QISSAATSH-GGPPGGKGPGQDRPPLG--PTVPYTEALQVFHHPVAQTP------LHEKP 1137 + S S PP P PPL P+ P + L P Q P L + P Sbjct: 605 GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 664 Query: 1138 YLPPPVSLFSFQHLVQHEPGQSPEFFS-TQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPT 1196 + PPP P SP +QA SL + P +PP PP A P P+ P+ Sbjct: 665 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP----ASP-PMSPS 719 Query: 1197 VLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVES 1256 P PQ P A P + PPS P + SA PL + LQ+P + Sbjct: 720 ATPP-----PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774 Query: 1257 HLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSA---PPLALPACPDT 1313 LP ++PLA + PP APPA ++ P A PP + P Sbjct: 775 SLP-----MSPLA----------------KPPPQAPPALATPPLQALPSPPASFPGQAPF 813 Query: 1314 MVSLVVPVR-VQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGAD 1372 S +P+ + T P + L Q V S +S T+ P+ P T+V G Sbjct: 814 SPSASLPMSPLATPPPQAPPVLAAPLLQ--VPPSPPASPTLQAPRRPPTPGPDTSVSGPR 871 Query: 1373 VH-EVGPGP 1380 + + PGP Sbjct: 872 LTLALAPGP 880 Score = 75.1 bits (183), Expect = 8e-13 Identities = 179/769 (23%), Positives = 267/769 (34%), Gaps = 141/769 (18%) Query: 734 KSQFGSPGPSDAARNLPLESTKSPAEPSKSVP---------SLEGPTGFQPRTPKPGSGS 784 K++ G+ + AAR L + + P P P G G +P + +G Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER--AGG 64 Query: 785 ESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPH-GRSAHSL 843 G ++ + + ++ + P+ GE P A+ SP P GR++ + Sbjct: 65 IGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124 Query: 844 QPKLVRQPNIQ------VPEILVTEEPDRP--------DTE-PEPPPKEPEKTE------ 882 +P + Q ++ V TE P R DT P P P Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184 Query: 883 -EFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQ------- 934 E P+ + + P + P K ++ +S S+ E S R PS Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKS-------VSSASEHSTTEPSPAARRRPSAGGGLQRP 237 Query: 935 -ESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSAS 993 ++S S + S+ + +P+ +PKP G L P P ++ + Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297 Query: 994 --EQSPNVSHSAHMTETRSKSFDYGS---LSLTGP-----SAPAPVAPPARVAPPERRKC 1043 SP + S T+ R + L T P + P P+APP+ APP + Sbjct: 298 PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL 357 Query: 1044 FLVRQASLSRPPES----------ELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAAT 1093 S+ P S L+ P + PS P + +LS + A T Sbjct: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQ-ATT 416 Query: 1094 SHGGP-------------------------PGGKGPGQDRPPLGP--TVPYTEALQVFHH 1126 S G P P P D PPL ++P + LQ Sbjct: 417 SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP--DSPPLQAPLSLPASPPLQTSLS 474 Query: 1127 PVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPP---LPP 1183 P A +PL + P +L S L H P Q+P S+ M L + PP PP Sbjct: 475 P-AVSPLSSPLTIHPLQALSS---LASHSP-QAP--LSSLIMPPLETQSSLAPPSLQTPP 527 Query: 1184 SLFQAPPLPLQPTVLHP------GQLHLPQLM--PHPANIPFRQPPSFLPMPYP-TSSAL 1234 + PPL P++ P L P L P PA P + PPS L P P T S++ Sbjct: 528 ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI 587 Query: 1235 SSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPA 1294 ++ P Q+ AL P LP L+PLAT P + + LPP+ P Sbjct: 588 ATP---PPQAPPALASPP--LQGLPS--PPLSPLAT------PPPQAPPXLALPPLQAPP 634 Query: 1295 SSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVA 1354 S A PLA P+ P +L V + P + S A+ Sbjct: 635 SPPASPPLSPLATPS-PQAPNALAVHLLQAPFSPPPSPPVQAPFSP---------PASPP 684 Query: 1355 LPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLP 1403 + PPS+ A +V P P A P P P+ P Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733 Score = 73.2 bits (178), Expect = 3e-12 Identities = 211/970 (21%), Positives = 322/970 (33%), Gaps = 193/970 (19%) Query: 486 PRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHSMPS 545 P RS S R + +P +H + KP+ L PP PP P Sbjct: 252 PARSGPSARGTPRAP----------AHPSQPKPKG--LQALRPPQVTPPRKDAAPALGPL 299 Query: 546 AACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYSSEE 605 ++ ++TP T + + + T P L P + PL S Sbjct: 300 SSSPLATP----------SPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS 349 Query: 606 PGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYY 665 PS + S P+ +T + + I Sbjct: 350 APPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTI----------------------- 386 Query: 666 CSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEE 725 +Q+ +++ + +P + + + + + L T + R+ + SL Sbjct: 387 -PPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS 445 Query: 726 EPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSE 785 P + +P A+ PL+++ SPA V L P P S Sbjct: 446 RPASTPPDSPPLQAPLSLPASP--PLQTSLSPA-----VSPLSSPLTIHPLQALSSLASH 498 Query: 786 SGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAP-HGRSAHSLQ 844 S + +S + ++ SS P+ L PL PS P P SA Sbjct: 499 S-PQAPLSSLIMPPLETQSSLAPPSLQTPPASLT--TPPLENLPSLAPPPLQTASAPLTT 555 Query: 845 PKLVRQP-----NIQVPEI-LVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPA 898 P L P +Q P L T P+ P + PPP+ P LA P Sbjct: 556 PHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPP------------ALASPPL 603 Query: 899 EKLPPKKKRLRLAEMAQSSGESSFESSVP-LSRSPSQESNVSLSGSSRSASFERDDHGKA 957 + LP L+ +A ++ ++P L PS ++ LS + Sbjct: 604 QGLPSPP----LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLA------------- 646 Query: 958 EAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQ-SPNVSHSAHMTETRSKSFDYG 1016 PSP + P L H+L P P + ++ S SP VS SA S Sbjct: 647 -TPSPQA---PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS---- 698 Query: 1017 SLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSS 1076 L P P +PPA +PP S + PP++ +A Q P P + Sbjct: 699 ---LAAPPLQVPPSPPA--SPP--------MSPSATPPPQAPPPLAAPPLQVP--PSPPA 743 Query: 1077 SKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEK 1136 S P + S+ PP P PPL VP + + P+A+ P Sbjct: 744 SPPMSPSAT------------PPPRVPPLLAAPPL--QVPPSPPASLPMSPLAKPP---- 785 Query: 1137 PYLPPPVSLFSFQHLVQHE---PGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPL 1193 P PP ++ Q L PGQ+P S S L++P PP P + AP L + Sbjct: 786 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP---PPQAPPVLAAPLLQV 842 Query: 1194 QPTVLHPGQLHLPQLMPHPA--------NIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQ 1245 P+ L P+ P P + P P P + S+ SG L S Sbjct: 843 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902 Query: 1246 FALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYS-------SDIRLPPVAPPASSSA 1298 A P ++ + P +A P E + S PP+A + A Sbjct: 903 SATSTPEELRGY------DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA 956 Query: 1299 PTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKF 1358 P PP P D + ++ +T P SAT A Sbjct: 957 PLPWPPATGPGSADGLCTI-----YETEGP--------------------ESATPAPGAL 991 Query: 1359 EEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSL 1418 + PS GT+ G G G S S +Q+R P + ++ + L S ++L L Sbjct: 992 DPGPSPGTS-GGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQH----LLSRTLL-L 1045 Query: 1419 EGSSSTAGGS 1428 + AGGS Sbjct: 1046 AAAEGAAGGS 1055 Score = 63.9 bits (154), Expect = 2e-09 Identities = 146/591 (24%), Positives = 203/591 (34%), Gaps = 86/591 (14%) Query: 1865 EDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEA--- 1921 E +S S S+ P P A R S G Q P + + + AT SS + + Sbjct: 203 EGPRKSVSSASEHSTTEPSP----AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 258 Query: 1922 ERLTASSCSMSSQSMP-GLPWLGPAPLGSVEKDTGSALSYKPVSP----------RRPWS 1970 R T + + SQ P GL L P + KD AL SP RP Sbjct: 259 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVP 318 Query: 1971 PSKEAGS--------RPPLARKHSLTK-NDSSPQRCSPAREPQASAPS--PPGLHVDPGR 2019 P A + PPLA L + S+P P A+ PS PP + P + Sbjct: 319 PPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ 378 Query: 2020 GMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRW------- 2072 +L P +Q+ P +L + P LS L+ TT G P T + Sbjct: 379 APPSLQT-IPPIQV-PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436 Query: 2073 ------SPGQAESPPRSAPPGKWALAGPGSPSAGEH-GPGLG-LDPRVLFPPAPLPHKLL 2124 SP + S P +PP + L+ P SP P + L + P L Sbjct: 437 TQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLA 496 Query: 2125 SRSPETCAS-----PWKAESR-SPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSH 2178 S SP+ S P + +S +P P L++ P L L + Sbjct: 497 SHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT------AS 550 Query: 2179 LPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQ 2238 PL + HL PCP A P+ L P S + A + Sbjct: 551 APLTTPHLETPPCP---------APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP 601 Query: 2239 E-RGRWSPTESSSASVSPVA--KVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGT 2295 +G SP S A+ P A ++ L + P P P H Sbjct: 602 PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 661 Query: 2296 GAPAEPTPT---HSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSS 2352 AP P P+ +P +PP + P P +Q+ P L +P P P A+PP+ S+ Sbjct: 662 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA-PPSLAAPPLQVPPSPPASPPMSPSA 720 Query: 2353 SVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPP 2403 + P L+ P SP S P A P RVPP Sbjct: 721 TPP---------PQAPPPLAAPPLQVPPSPPASPPMSPSA---TPPPRVPP 759 Score = 63.5 bits (153), Expect = 2e-09 Identities = 146/572 (25%), Positives = 193/572 (33%), Gaps = 138/572 (24%) Query: 1875 SRPSSEAPPPGPPHALRADSSPILGPQ---PPDAPASGTEATRGSSVSEAERLTASSCSM 1931 +R + P PG P A S G + P AP++ R +E R + SS S Sbjct: 160 ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA-----RPRPPTEGPRKSVSSASE 214 Query: 1932 SSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKND 1991 S + P P + RRP S G + P +R S + Sbjct: 215 HSTTEPS-----------------------PAARRRP---SAGGGLQRPASRSLSSSATP 248 Query: 1992 -SSPQRCSPARE--PQASA----PSPPGLH------VDPGRGMGALPCGSPRLQLSPL-T 2037 SSP R P+ P+A A P P GL V P R A P P L SPL T Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR-KDAAPALGP-LSSSPLAT 306 Query: 2038 LCPLG---RELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGP 2094 P G R + P + + L T P P +P P SAPP L P Sbjct: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL------PLAPPSPSAPPSLQTLPSP 360 Query: 2095 GSPSAGEHGPGLGLDPRVL------FPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGP 2148 + + P + P PP +PH L S S + SP S + S Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS--- 417 Query: 2149 AHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGA 2208 L S A H F +T+ ++ S P P+ + A P Sbjct: 418 ---LGSPTLQATHSFLTMSPRQTQASLTS-----PSRPASTPPDSPPLQAPLSLPASPPL 469 Query: 2209 HPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTE--SSSASVSPVAKVSKFTLSS 2266 +L P VS S S LT P + SS AS SP A +S + Sbjct: 470 QTSLSPA-----VSPLS---SPLT----------IHPLQALSSLASHSPQAPLSSLIM-- 509 Query: 2267 ELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPP----DTLPRPPQGRR 2322 PP T P+ TP S TPP +L PP Sbjct: 510 --------------------PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA 549 Query: 2323 AAQSWSPRLESPRAP------TNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPR 2376 +A +P LE+P P P P TPP + SS+ + P L+ P Sbjct: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI------ATPPPQAPPALASPPL 603 Query: 2377 TRQDSP--KPSGSGEPRAHPH--QPEDRVPPN 2404 SP P + P+A P P + PP+ Sbjct: 604 QGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635 Score = 62.4 bits (150), Expect = 5e-09 Identities = 130/531 (24%), Positives = 179/531 (33%), Gaps = 97/531 (18%) Query: 1874 LSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSS 1933 L+ P E PP P L+A SP+ P PP+ P+S AT A ++S Sbjct: 553 LTTPHLETPPCPAPCPLQAPPSPLTTP-PPETPSS--IATPPPQAPPA---------LAS 600 Query: 1934 QSMPGLPWLGPAPLGSVEKDTGSALSYKPV----SP--RRPWSPSKEAGSRPPLARKHSL 1987 + GLP +PL + L+ P+ SP P SP + P A L Sbjct: 601 PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 660 Query: 1988 TKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP 2047 + SP P + P + SPP P +P Q P P ++ P Sbjct: 661 LQAPFSPPPSPPVQAPFSPPASPP-----------VSPSATPPSQAPPSLAAP-PLQVPP 708 Query: 2048 RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLG 2107 + P P SP+ +P PP +APP + + P SP Sbjct: 709 -----------SPPASPPMSPSA--TPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT--- 752 Query: 2108 LDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHP--LSSRPFSALHDFHG 2165 PP +P L + + SP + SP P P P L++ P AL Sbjct: 753 -------PPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPA 805 Query: 2166 HILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTL-------LPGPTA 2218 + + + LP+ P + + V P A PTL PGP Sbjct: 806 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 865 Query: 2219 AWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSS--ELEGGDYPKE 2276 S G LT A S + SS+ S +A S S+ EL G D E Sbjct: 866 ------SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 919 Query: 2277 RERTGGGPGRPPD-----------WTPHGT------GAPAEPTPTHSPCTPPDTLPRPPQ 2319 GG PP W+ GAP P P PP T P Sbjct: 920 ----GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP-----WPPATGPGSAD 970 Query: 2320 GRRAAQSWSPRLESPRAPTNPEPSATPPLD-RSSSVGCLAEASARFPARTR 2369 G + AP +P +P ++ G A AS+R P + R Sbjct: 971 GLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 1021 Score = 56.6 bits (135), Expect = 3e-07 Identities = 137/558 (24%), Positives = 182/558 (32%), Gaps = 138/558 (24%) Query: 1874 LSRPSSEAPP-----PGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASS 1928 L+ PS APP P PP + + P + P AP S ++ S Sbjct: 343 LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPS-------LQTIPPIQVPHSL 395 Query: 1929 CSMSSQSMPGLPWLGPAPLGSVEKDTG-------SALSYKPVSPRRPW----SPSKEAGS 1977 S S Q+ P P L S++ T + S+ +SPR+ SPS+ A + Sbjct: 396 TSPSLQAPPS-----PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAST 450 Query: 1978 ---RPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLS 2034 PPL SL + SPA P +S L + P + + +L SP+ LS Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSP-----LTIHPLQALSSLASHSPQAPLS 505 Query: 2035 PLTLCPLGRE--LAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALA 2092 L + PL + LAP + TT P E+ P APP + Sbjct: 506 SLIMPPLETQSSLAPPSLQTPPASLTTPP---------------LENLPSLAPPPLQTAS 550 Query: 2093 GPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSR-SPETCASPWKAESRSPSCSPGPAHP 2151 P + P + PP P P L + SP T P E+ S +P P P Sbjct: 551 APLTT------------PHLETPPCPAPCPLQAPPSPLTTPPP---ETPSSIATPPPQAP 595 Query: 2152 --LSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAH 2209 L+S P L LA L L L P P A P Sbjct: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPP--LQAPPSP----------PASPPLS 643 Query: 2210 PTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELE 2269 P P P A + + + +SP +S VSP A Sbjct: 644 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP--ASPPVSPSAT----------- 690 Query: 2270 GGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPP--DTLPRPPQGRRAAQSW 2327 PP P AP P P +PP + PPQ Sbjct: 691 -----------------PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA------- 726 Query: 2328 SPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGS 2387 P L +P P P A+PP+ SA P R L P Q P P Sbjct: 727 PPPLAAPPLQVPPSPPASPPM----------SPSATPPPRVPPLLAAP-PLQVPPSP--- 772 Query: 2388 GEPRAHPHQPEDRVPPNA 2405 P + P P + PP A Sbjct: 773 --PASLPMSPLAKPPPQA 788 Score = 41.2 bits (95), Expect = 0.012 Identities = 127/483 (26%), Positives = 165/483 (34%), Gaps = 112/483 (23%) Query: 2000 AREPQASAPSPPGLHVDPGRGMGALPCGSPRLQ--LSPLTLCPLGRELA----PRAHVLS 2053 AR P A AP GL + P GSPR ++P L LG A P A Sbjct: 14 ARTPAARAP---GL-------LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63 Query: 2054 KLEGTTDP-GLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDP-- 2110 + G T P PR PTR S G + P S PP G +P A PG P Sbjct: 64 GIGGATIPESAPRAGPTR--SAGTSSRNPASRPPASGR--GERAPPAKNTSPGPVSSPGR 119 Query: 2111 -RVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCS--------------PGPAHPLSSR 2155 P PL K L S E + KA + +P S PG P +R Sbjct: 120 ASGTTRPGPLGQKGLRISAEETVARGKA-TEAPKRSALSAGARRDTSGPTPGTPSPAMAR 178 Query: 2156 PFSALHDFHGHILARTEENIFSHLPLH---------SQHLTRAPCPLIPI-----GGIQM 2201 A G L R + P S+H T P P GG+Q Sbjct: 179 RSRAAGTEVG--LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236 Query: 2202 VQARP-GAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRW----------SPTESSS 2250 +R + T L P SG S G+ A +Q + + P + ++ Sbjct: 237 PASRSLSSSATPLSSPAR---SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293 Query: 2251 ASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPD--WTP-HGTGAPAEPTPTHSP 2307 ++ P+ S L++ G T P PPD TP T P+ P T P Sbjct: 294 PALGPL---SSSPLATPSPSG--------TKARPVPPPDNAATPLPATLPPSPPLATPLP 342 Query: 2308 CTPP--------DTLPRPP----------------QGRRAAQSWSPRLESPRAPTNPEPS 2343 PP TLP PP Q + Q+ P ++ P + T+P Sbjct: 343 LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQT-IPPIQVPHSLTSPSLQ 401 Query: 2344 ATP-PLDRSSSVGCLAEASARFPARTRNLSGEPRTRQ---DSPKPSGSGEPRAHPHQPED 2399 A P PL SS + S A L+ PR Q SP S P + P Q Sbjct: 402 APPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL 461 Query: 2400 RVP 2402 +P Sbjct: 462 SLP 464 Score = 35.4 bits (80), Expect = 0.68 Identities = 35/119 (29%), Positives = 50/119 (42%), Gaps = 35/119 (29%) Query: 442 PLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRS-SMESP 500 PL T P++ PLS P T + P ++ S S S ++P Sbjct: 468 PLQTSLSPAVSPLSSPLT------------------------IHPLQALSSLASHSPQAP 503 Query: 501 KSSLYREPLSSHSEKTKPEQSLLSLQHPPS--TAPP---VPLLRSHSMPSAACTISTPH 554 SSL PL + S P SLQ PP+ T PP +P L + +A+ ++TPH Sbjct: 504 LSSLIMPPLETQSSLAPP-----SLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH 557 Score = 34.3 bits (77), Expect = 1.5 Identities = 42/171 (24%), Positives = 67/171 (39%), Gaps = 12/171 (7%) Query: 16 SPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTG 75 +P TK + +++ P P + + + L P P P S+ S T Sbjct: 306 TPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP-SAPPSLQTLPSPPATP 364 Query: 76 QQQKPPKR--PPIEASVHISQLPQ----HPLT-PAFMSPGKPEHL--LEGSTWQLVDPMR 126 Q PP PP++A + +P H LT P+ +P P L L+ +T ++ Sbjct: 365 PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424 Query: 127 PGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPR--PSQVSLKP 175 S ++P S PS + PP+ P + +P P Q SL P Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSP 475 Score = 34.3 bits (77), Expect = 1.5 Identities = 34/131 (25%), Positives = 46/131 (35%), Gaps = 25/131 (19%) Query: 38 PGSGTAATQESPAQELLAPQP-FPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLP 96 P A P Q L +P FPG + S + PP+ PP+ A+ + P Sbjct: 785 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 844 Query: 97 QHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSF--------VAPGLHPQSQLLPSH 148 P +P +P +P PGP S +APG P PS Sbjct: 845 SPPASPTLQAPRRPP--------------TPGPDTSVSGPRLTLALAPGPPPPPSRSPS- 889 Query: 149 ASIIPPEDLPG 159 S + DL G Sbjct: 890 -STLSGPDLAG 899 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 88.2 bits (217), Expect = 9e-17 Identities = 151/594 (25%), Positives = 212/594 (35%), Gaps = 98/594 (16%) Query: 849 RQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRL 908 R P + P +L RP P PPP P L L A +K Sbjct: 15 RTPAARAPGLLTP----RPPGSPRPPP-----------PVTPAALRVLGAAGAVGRKP-- 57 Query: 909 RLAEMAQSSGESSFESSVPLSRSPSQESNVSLSG-SSRSASFERDDHGKAEAPSPSSDM- 966 LAE A G ++ S P + P++ S SG R+ + G +P +S Sbjct: 58 -LAERAGGIGGATIPESAPRA-GPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 115 Query: 967 RPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAP 1026 RP PLG L + + AR A ++S + + T +GP+ Sbjct: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT--------------SGPTPG 161 Query: 1027 APVAPPARVAPPERRKCFLVRQASLSRP-PESE---LEVAPKGRQESEEPQPSSSK-PSA 1081 P AR + + L R A +RP P +E V+ + EP P++ + PSA Sbjct: 162 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 221 Query: 1082 KSSLSQ-----ISSAATSHGGPP--GGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLH 1134 L + +SS+AT P G G R P P+ P + LQ P P Sbjct: 222 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 281 Query: 1135 E----------------KPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSM 1178 + P PP S + P P +T S L + +S Sbjct: 282 DAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF 341 Query: 1179 ---PPL----------PPSL----FQAPPLPLQPTVLHPGQLHLPQ----LMPHPANIPF 1217 PPL PP+L QAPP P L P PQ L H PF Sbjct: 342 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 401 Query: 1218 RQPPS---FLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAG 1274 PPS P P S +S P Q+ +L P P ++P AT Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461 Query: 1275 LSPSTEYSSDIRL---PPVAPPASSSAPTSA---PPLALPACPDTMVSLVVPVR-VQTNM 1327 P + ++L PP APPA ++ P A PP + P S +P+ + T Sbjct: 462 APPPLA-APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520 Query: 1328 PSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVH-EVGPGP 1380 P + L Q V S +S T+ P+ P T+V G + + PGP Sbjct: 521 PQAPPVLAAPLLQ--VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 572 Score = 72.0 bits (175), Expect = 7e-12 Identities = 183/770 (23%), Positives = 257/770 (33%), Gaps = 153/770 (19%) Query: 711 PLRKRRKEKSLGDEEEPPAFESTKSQFGSPG-PSDAARNLPL----------------ES 753 P R R S E PPA ++ SPG S R PL ++ Sbjct: 79 PTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 138 Query: 754 TKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLE 813 T++P + S + +G P TP P S R E+ + + S E Sbjct: 139 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRS----RAAGTEVGLPRPAPSARPRPPTE 194 Query: 814 QP-SGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPE 872 P + + PSP + LQ R + + P R Sbjct: 195 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL---SSPARSGPSAR 251 Query: 873 PPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSP 932 P+ P + P+ A P + PP+K + A + G PLS SP Sbjct: 252 GTPRAPAHPSQ---PKPKGLQALRPPQVTPPRK------DAAPALG--------PLSSSP 294 Query: 933 SQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSA 992 L+ S SA PSPS+ + L + T PS + + Sbjct: 295 -------LATPSPSAP-----------PSPSAPPSLQTLPSPPATPPS--------QATT 328 Query: 993 SEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVA-PPARVAPPERRKCFLVRQASL 1051 S SP + T + S L+ P AP +A PP + P L A+ Sbjct: 329 SLGSPTLQ----ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 384 Query: 1052 SRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPL 1111 S + L V S P P P + + +S +AT PP P PPL Sbjct: 385 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT----PPSQAPPSLAAPPL 440 Query: 1112 GPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSL 1171 VP + P A P P PPP++ Q + P Q+P +T + +L Sbjct: 441 --QVPPSPPASPPMSPSATPP----PQAPPPLAAPPLQ--LAKPPPQAPPALATPPLQAL 492 Query: 1172 LSSPYSMP---------PLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPS 1222 S P S P LP S PP P P VL L +P P P P Q P Sbjct: 493 PSPPASFPGQAPFSPSASLPMSPLATPP-PQAPPVLAAPLLQVP---PSPPASPTLQAPR 548 Query: 1223 FLPMPYPTSS--------ALSSGFFLPLQSQFALQLPG-DVESHLPQIKTSLAPLA---- 1269 P P P +S AL+ G P + L G D+ H ++ L Sbjct: 549 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 608 Query: 1270 --TGSAGLSPSTEYS---------SDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLV 1318 G A SP + S PP+A + AP PP P D + ++ Sbjct: 609 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTI- 667 Query: 1319 VPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGP 1378 +T P SAT A + PS GT+ G G Sbjct: 668 ----YETEGP--------------------ESATPAPGALDPGPSPGTS-GGKAAAGAGA 702 Query: 1379 GPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGS 1428 G S S +Q+R P + ++ + L S ++L L + AGGS Sbjct: 703 GASSRSPKQARLGELPLGALQASVVQH----LLSRTLL-LAAAEGAAGGS 747 Score = 56.2 bits (134), Expect = 4e-07 Identities = 124/509 (24%), Positives = 176/509 (34%), Gaps = 95/509 (18%) Query: 1870 SQDELSRPSSEAPP-PGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASS 1928 S L+ PS APP P P +L+ P PP P S + GS +A S Sbjct: 291 SSSPLATPSPSAPPSPSAPPSLQTL------PSPPATPPSQATTSLGSPTLQATHSFLPS 344 Query: 1929 CSMSSQSMP---GLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKH 1985 +S + P P L PL A P SP P SP + P A Sbjct: 345 PPLSPLATPPPQAPPALALPPL--------QAPPSPPASP--PLSPLATPSPQAPNALAV 394 Query: 1986 SLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGREL 2045 L + SP P + P + SPP P +P Q P P ++ Sbjct: 395 HLLQAPFSPPPSPPVQAPFSPPASPP-----------VSPSATPPSQAPPSLAAP-PLQV 442 Query: 2046 APRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPG 2105 P + P P SP+ +P PP +APP + A P +P P Sbjct: 443 PP-----------SPPASPPMSPSA--TPPPQAPPPLAAPPLQLAKPPPQAP------PA 483 Query: 2106 LGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGP-AHPLSSRPFSALHDFH 2164 L P P P S + SP + SP +P P A P+ + P Sbjct: 484 LATPPLQALPSPP-----ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP-------- 530 Query: 2165 GHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQA-RPGAHPTLLPGPTAAWVSG 2223 L + + + L + P P + G ++ A PG P P++ +SG Sbjct: 531 ---LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST-LSG 586 Query: 2224 --FSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTG 2281 +G S T E P ++AS P A+++ ++ G P Sbjct: 587 PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG---PAPPLAFR 643 Query: 2282 GGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPE 2341 G PG P W P TG P CT +T +S +P AP + Sbjct: 644 GAPGAPLPWPP-ATG----PGSADGLCTIYET--------EGPESATP------APGALD 684 Query: 2342 PSATPPLD-RSSSVGCLAEASARFPARTR 2369 P +P ++ G A AS+R P + R Sbjct: 685 PGPSPGTSGGKAAAGAGAGASSRSPKQAR 713 Score = 52.0 bits (123), Expect = 7e-06 Identities = 105/483 (21%), Positives = 150/483 (31%), Gaps = 46/483 (9%) Query: 1877 PSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSM 1936 P+ + PP RA + P P +P + TR + + ++ +++ Sbjct: 79 PTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 138 Query: 1937 PGLPWLGPAPLGSVEKDTGSALSY-KPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQ 1995 P G+ +G P RR + E G P + + Sbjct: 139 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 198 Query: 1996 RCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKL 2055 S A E + PSP P G G LQ P R L+ A LS Sbjct: 199 SVSSASEHSTTEPSPAARR-RPSAGGG--------LQR------PASRSLSSSATPLSSP 243 Query: 2056 EGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPG-SPSAGEHGPGLG-LDPRVL 2113 R P+ R +P P + P G AL P +P + P LG L L Sbjct: 244 A--------RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 295 Query: 2114 FPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEE 2173 P+P S P A P SP +P P+ +S L H + + Sbjct: 296 ATPSP------SAPPSPSAPPSLQTLPSPPATP-PSQATTSLGSPTLQATHSFLPSPPLS 348 Query: 2174 NIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTG 2233 + + P L P P A P P P P A + + Sbjct: 349 PLATPPPQAPPALALPPLQAPP-----SPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 403 Query: 2234 AREAQERGRWSPTESS--SASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWT 2291 + +SP S S S +P ++ + L+ P PP Sbjct: 404 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 463 Query: 2292 PHGTGAP---AEPTPTHSPC--TPP-DTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSAT 2345 P P A+P P P TPP LP PP +SP P +P P Sbjct: 464 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 523 Query: 2346 PPL 2348 PP+ Sbjct: 524 PPV 526 Score = 51.2 bits (121), Expect = 1e-05 Identities = 98/408 (24%), Positives = 139/408 (34%), Gaps = 54/408 (13%) Query: 1979 PPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGAL---PCGSPRLQLSP 2035 P A + T+ P R P A SP G PGR G P G L++S Sbjct: 71 PESAPRAGPTRTSRPPASGRGERAPPAKNTSP-GPVSSPGRASGTTRPGPLGQKGLRISA 129 Query: 2036 LTLCPLGREL-APRAHVLSK-----LEGTTDPGLPRYSPTRRW-SPGQAESPPRSAPPGK 2088 G+ AP+ LS G T PG P + RR + G PR AP + Sbjct: 130 EETVARGKATEAPKRSALSAGARRDTSGPT-PGTPSPAMARRSRAAGTEVGLPRPAPSAR 188 Query: 2089 WALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKL----------LSRSPETCASPWKAE 2138 P P+ G P+P + SRS + A+P + Sbjct: 189 -----PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243 Query: 2139 SRSPSCSPG----PAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLI 2194 +RS + G PAHP +P + ++ + PL S L P P Sbjct: 244 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA-TPSPSA 302 Query: 2195 PIGGIQMVQARPGAHPTL--LPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSAS 2252 P P A P+L LP P A S + G+ Q + P+ S Sbjct: 303 P--------PSPSAPPSLQTLPSPPATPPSQ----ATTSLGSPTLQATHSFLPSPPLSPL 350 Query: 2253 VSPVAKVSKFTLSSELEGGDYPKERERTGG----GPGRPPDWTPHGTGAPAEPTPT---H 2305 +P + L+ P P P H AP P P+ Sbjct: 351 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 410 Query: 2306 SPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSS 2353 +P +PP + P P +Q+ P L +P P P A+PP+ S++ Sbjct: 411 APFSPPASPPVSPSATPPSQA-PPSLAAPPLQVPPSPPASPPMSPSAT 457 Score = 47.4 bits (111), Expect = 2e-04 Identities = 102/373 (27%), Positives = 130/373 (34%), Gaps = 72/373 (19%) Query: 2000 AREPQASAPSPPGLHVDPGRGMGALPCGSPRLQ--LSPLTLCPLGRELA----PRAHVLS 2053 AR P A AP GL + P GSPR ++P L LG A P A Sbjct: 14 ARTPAARAP---GL-------LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63 Query: 2054 KLEGTTDP-GLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRV 2112 + G T P PR PTR P A APP K GP S G Sbjct: 64 GIGGATIPESAPRAGPTRTSRP-PASGRGERAPPAKNTSPGPVSSPGRASGTTR------ 116 Query: 2113 LFPPAPLPHKLLSRSPETCASPWKA-ESRSPSCSPGPAHPLSSRPFSALHDFHGHILART 2171 P PL K L S E + KA E+ S A +S P +AR Sbjct: 117 ---PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS---PAMARR 170 Query: 2172 EENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDL 2231 + + L + P P P G + + H T P P AA +GGG Sbjct: 171 SRAAGTEVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEPSP-AARRRPSAGGGLQR 227 Query: 2232 TGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSE--LEGGDYPKERERTGGGPGRPPD 2289 +R S S+S +P++ ++ S+ +P + + G RPP Sbjct: 228 PASR------------SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 275 Query: 2290 WTP-HGTGAPA------EPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEP 2342 TP APA P T SP PP P P P T P P Sbjct: 276 VTPPRKDAAPALGPLSSSPLATPSPSAPPS--PSAP---------------PSLQTLPSP 318 Query: 2343 SATPPLDRSSSVG 2355 ATPP ++S+G Sbjct: 319 PATPPSQATTSLG 331 Score = 40.8 bits (94), Expect = 0.016 Identities = 57/215 (26%), Positives = 81/215 (37%), Gaps = 23/215 (10%) Query: 2196 IGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSP 2255 IGG + ++ P A PT P A+ G + T GR S T Sbjct: 65 IGGATIPESAPRAGPTRTSRPPASG-RGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123 Query: 2256 VAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEP-------TPTHSPC 2308 ++S + + + PK R G R GT +PA T P Sbjct: 124 GLRISAEETVARGKATEAPK-RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 182 Query: 2309 TPPDTLPRPP-QGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPAR 2367 P PRPP +G R + S + S + T P P+A R S+ G L ++R Sbjct: 183 PAPSARPRPPTEGPRKSVSSA----SEHSTTEPSPAARR---RPSAGGGLQRPASR---- 231 Query: 2368 TRNLSGEPRTRQDSPKPSGSGEPR--AHPHQPEDR 2400 + + S P + PS G PR AHP QP+ + Sbjct: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 266 Score = 34.3 bits (77), Expect = 1.5 Identities = 34/131 (25%), Positives = 46/131 (35%), Gaps = 25/131 (19%) Query: 38 PGSGTAATQESPAQELLAPQP-FPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLP 96 P A P Q L +P FPG + S + PP+ PP+ A+ + P Sbjct: 477 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 536 Query: 97 QHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSF--------VAPGLHPQSQLLPSH 148 P +P +P +P PGP S +APG P PS Sbjct: 537 SPPASPTLQAPRRPP--------------TPGPDTSVSGPRLTLALAPGPPPPPSRSPS- 581 Query: 149 ASIIPPEDLPG 159 S + DL G Sbjct: 582 -STLSGPDLAG 591 Score = 33.5 bits (75), Expect = 2.6 Identities = 55/243 (22%), Positives = 82/243 (33%), Gaps = 16/243 (6%) Query: 1361 PPSKGTTVCGADVHEVGPGP-SGLSEEQSRAFPTPY----LRVPV--TLPERKGTSLSSE 1413 PP+ G PGP S P P LR+ T+ K T Sbjct: 85 PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKR 144 Query: 1414 SILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPCSVVLT 1473 S LS T+G + SPA + + + +++ E P V + Sbjct: 145 SALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE--GPRKSVSS 202 Query: 1474 STEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALSHGTAPGSEALKE 1533 ++E + L+ +S S S T PL PA S +A G+ Sbjct: 203 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT----PLSSPARSGPSARGTPRAPA 258 Query: 1534 YPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVL 1593 +P +P +GL L + + P+L P SS PL+ S S S + L Sbjct: 259 HPS---QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315 Query: 1594 QFP 1596 P Sbjct: 316 PSP 318 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 85.9 bits (211), Expect = 4e-16 Identities = 159/662 (24%), Positives = 234/662 (35%), Gaps = 93/662 (14%) Query: 755 KSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERR---TTSKEISVIQHTSSFEKSDS 811 K+ A + P+ P PR P G R T + V+ + + Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPP--------GSPRPPPPVTPAALRVLGAAGAVGRKPL 58 Query: 812 LEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEE-PDRPDTE 870 E+ G+ G P S P A RSA + R P + P E P +T Sbjct: 59 AERAGGIGGATIP----ESAPRAGPTRSAGTSS----RNPASRPPASGRGERAPPAKNTS 110 Query: 871 PEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSR 930 P P + + Q ++ AE+ + K + + S + ++S P Sbjct: 111 PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 170 Query: 931 SPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRR 990 +PS +++ SR+A E P+PS+ RP G +V S H+ Sbjct: 171 TPSP----AMARRSRAAGTEVG----LPRPAPSARPRPPTEGPRK-SVSSASEHSTTEPS 221 Query: 991 SASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQAS 1050 A+ + P+ +RS S S+ P++ PAR P R Sbjct: 222 PAARRRPSAGGGLQRPASRSLS-----------SSATPLSSPARSGPSAR---------G 261 Query: 1051 LSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPP 1110 R P + PKG Q PQ + + A +L +SS+ + P PP Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQ--SQAPP 319 Query: 1111 LGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSS 1170 P P++ +L TPL P PP S + P P +T S Sbjct: 320 TLPATPHSSSLTC----QLATPL---PLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP 372 Query: 1171 LLSSPYSM---PPL----------PPSL----FQAPPLPLQPTVLHPGQLHLPQ----LM 1209 L + +S PPL PP+L QAPP P L P PQ L Sbjct: 373 TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 432 Query: 1210 PHPANIPFRQPPS---FLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLA 1266 H PF PPS P P S +S P Q+ +L P P ++ Sbjct: 433 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 492 Query: 1267 PLATGSAGLSPSTEYSSDIRL---PPVAPPASSSAPTSA---PPLALPACPDTMVSLVVP 1320 P AT P + ++L PP APPA ++ P A PP + P S +P Sbjct: 493 PSATPPPQAPPPLA-APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 551 Query: 1321 VR-VQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVH-EVGP 1378 + + T P + L Q V S +S T+ P+ P T+V G + + P Sbjct: 552 MSPLATPPPQAPPVLAAPLLQ--VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 609 Query: 1379 GP 1380 GP Sbjct: 610 GP 611 Score = 79.0 bits (193), Expect = 5e-14 Identities = 138/578 (23%), Positives = 192/578 (33%), Gaps = 107/578 (18%) Query: 849 RQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRL 908 R P + P +L RP P PPP P L L A +K Sbjct: 15 RTPAARAPGLLTP----RPPGSPRPPP-----------PVTPAALRVLGAAGAVGRKP-- 57 Query: 909 RLAEMAQSSGESSFESSVPLS---RSPSQESNVSLSGSSRSASFERDDHGKAEAPSP--- 962 LAE A G ++ S P + RS S S S ER K +P P Sbjct: 58 -LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116 Query: 963 ----SSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSL 1018 S RP PLG L + + AR A ++S + + T Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT------------ 164 Query: 1019 SLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRP-PESE---LEVAPKGRQESEEPQP 1074 +GP+ P AR + + L R A +RP P +E V+ + EP P Sbjct: 165 --SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP 222 Query: 1075 SSSK-PSAKSSLSQ-----ISSAATSHGGPP--GGKGPGQDRPPLGPTVPYTEALQVFHH 1126 ++ + PSA L + +SS+AT P G G R P P+ P + LQ Sbjct: 223 AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282 Query: 1127 PVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLF 1186 P P + + A+ L SSP + P P + Sbjct: 283 PQVTPPRKD----------------------------AAPALGPLSSSPLATPS-PSAAL 313 Query: 1187 QAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQ-PPSFLPMPYPTSSALSSGFFLPLQSQ 1245 Q+ P P H L P P P PPS +P P ++ P Q+ Sbjct: 314 QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATP-------PSQAT 366 Query: 1246 FALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPL 1305 +L P +H L+PLAT P + + LPP+ P S A PL Sbjct: 367 TSLGSPTLQATHSFLPSPPLSPLAT------PPPQAPPALALPPLQAPPSPPASPPLSPL 420 Query: 1306 ALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKG 1365 A P+ P +L V + P + S A+ + PPS+ Sbjct: 421 ATPS-PQAPNALAVHLLQAPFSPPPSPPVQAPFSP---------PASPPVSPSATPPSQA 470 Query: 1366 TTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLP 1403 A +V P P A P P P+ P Sbjct: 471 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 508 Score = 70.1 bits (170), Expect = 2e-11 Identities = 175/758 (23%), Positives = 256/758 (33%), Gaps = 125/758 (16%) Query: 724 EEEPPAFESTKSQFGSPG-PSDAARNLPL----------------ESTKSPAEPSKSVPS 766 E PPA ++ SPG S R PL ++T++P + S + Sbjct: 101 ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 160 Query: 767 LEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQP-SGLEGEDKPL 825 +G P TP P S R E+ + + S E P + + Sbjct: 161 RRDTSGPTPGTPSPAMARRS----RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS 216 Query: 826 AQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQ 885 PSP + LQ R + + P R P+ P + Sbjct: 217 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPL---SSPARSGPSARGTPRAPAHPSQ-- 271 Query: 886 WPQRSQTLAQLPAEKLPPKKKRL-RLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSS 944 P+ A P + PP+K L ++ S + S+ S++P + + S Sbjct: 272 -PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPP---TLPATPHS 327 Query: 945 RSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAH 1004 S + + PSPS+ + L + T PS + + S SP + Sbjct: 328 SSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS--------QATTSLGSPTLQ---- 375 Query: 1005 MTETRSKSFDYGSLSLTGPSAPAPVA-PPARVAPPERRKCFLVRQASLSRPPESELEVAP 1063 T + S L+ P AP +A PP + P L A+ S + L V Sbjct: 376 ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 435 Query: 1064 KGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQV 1123 S P P P + + +S +AT PP P PPL VP + Sbjct: 436 LQAPFSPPPSPPVQAPFSPPASPPVSPSAT----PPSQAPPSLAAPPL--QVPPSPPASP 489 Query: 1124 FHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMP---- 1179 P A P P PPP++ Q + P Q+P +T + +L S P S P Sbjct: 490 PMSPSATPP----PQAPPPLAAPPLQ--LAKPPPQAPPALATPPLQALPSPPASFPGQAP 543 Query: 1180 -----PLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSS-- 1232 LP S PP P P VL L +P P P P Q P P P P +S Sbjct: 544 FSPSASLPMSPLATPP-PQAPPVLAAPLLQVP---PSPPASPTLQAPRRPPTPGPDTSVS 599 Query: 1233 ------ALSSGFFLPLQSQFALQLPG-DVESHLPQIKTSLAPLA------TGSAGLSPST 1279 AL+ G P + L G D+ H ++ L G A SP Sbjct: 600 GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 659 Query: 1280 EYS---------SDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSY 1330 + S PP+A + AP PP P D + ++ +T P Sbjct: 660 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTI-----YETEGP-- 712 Query: 1331 GSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRA 1390 SAT A + PS GT+ G G G S S +Q+R Sbjct: 713 ------------------ESATPAPGALDPGPSPGTS-GGKAAAGAGAGASSRSPKQARL 753 Query: 1391 FPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGS 1428 P + ++ + L S ++L L + AGGS Sbjct: 754 GELPLGALQASVVQH----LLSRTLL-LAAAEGAAGGS 786 Score = 53.1 bits (126), Expect = 3e-06 Identities = 128/560 (22%), Positives = 161/560 (28%), Gaps = 91/560 (16%) Query: 1875 SRPSSEAPPPGPPHALRADSSPILG-------PQPPDAPASGTEATRGSSVSEAERLTAS 1927 +R + P PG P A S G P P P TE R S S +E T Sbjct: 160 ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 219 Query: 1928 SCSMS----------------SQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSP 1971 + S S P PA G + T A P P +P Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA----PAHPSQPKPK 275 Query: 1972 SKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAP----SPPGLHVDPGRGMGALPCG 2027 +A P + P SP P SA +PP L P Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLA 335 Query: 2028 SPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAES----PPRS 2083 +P P P + P + TT G P T + P S PP Sbjct: 336 TPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 395 Query: 2084 APPGKWAL----AGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAES 2139 APP AL A P P++ P P+ P L LL SP Sbjct: 396 APPA-LALPPLQAPPSPPASPPLSPLATPSPQA---PNALAVHLLQAPFSPPPSPPVQAP 451 Query: 2140 RSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGG- 2198 SP SP P P ++ P A L S P S T P P+ Sbjct: 452 FSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPAS--PPMSPSATPPPQAPPPLAAP 508 Query: 2199 -IQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVA 2257 +Q+ + P A P L P A S A G+ + S+S +SP+A Sbjct: 509 PLQLAKPPPQAPPALATPPLQALPS------------PPASFPGQAPFSPSASLPMSPLA 556 Query: 2258 KVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLP-R 2316 PP P AP P P +P P R Sbjct: 557 ----------------------------TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 588 Query: 2317 PPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASA--RFPARTRNLSGE 2374 PP PRL AP P P + P S +S+ P R Sbjct: 589 PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG 648 Query: 2375 PRTRQDSPKPSGSGEPRAHP 2394 P + P + HP Sbjct: 649 PEGGAAASPPPDAELAACHP 668 Score = 48.1 bits (113), Expect = 1e-04 Identities = 115/456 (25%), Positives = 150/456 (32%), Gaps = 97/456 (21%) Query: 1874 LSRPSSEAPPPGPPHALRADSSPILGPQPP-----DAPASGTEATRGSSVSEAERLTASS 1928 L+ PS +AP H L+A SP P PP PAS + + S+A A+ Sbjct: 420 LATPSPQAPNALAVHLLQAPFSP--PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 477 Query: 1929 CSMSSQSMPGLPWLGPAPLGSVEKDTGSA------LSYKPVSPRRPWSPSKEAGSRPPLA 1982 S P P + P+ + A P +P +P +A PP + Sbjct: 478 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS 537 Query: 1983 RKHSLTKNDSSPQRCSPAREPQASAP---SPPGLHVDPGRGMGALPCGSPRLQLS----- 2034 + S+ SP P AP + P L V P P SP LQ Sbjct: 538 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS------PPASPTLQAPRRPPT 591 Query: 2035 ------------PLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSP-------- 2074 L L P G P S L G P L +S + +P Sbjct: 592 PGPDTSVSGPRLTLALAP-GPPPPPSRSPSSTLSG---PDLAGHSSSATSTPEELRGYDS 647 Query: 2075 ----GQAESPPRSAP-----PGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKL-- 2123 G A SPP A P W+ GP P A PG L +PPA P Sbjct: 648 GPEGGAAASPPPDAELAACHPAAWS-RGPAPPLAFRGAPGAPLP----WPPATGPGSADG 702 Query: 2124 LSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHS 2183 L ET P A + PGP+ S G A S P Sbjct: 703 LCTIYET-EGPESATPAPGALDPGPSPGTSG----------GKAAAGAGAGASSRSP--- 748 Query: 2184 QHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGG-----GSDLTGAREA- 2237 +A +P+G +Q + TLL G GG G +TG A Sbjct: 749 ---KQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAA 805 Query: 2238 ---QERGRW----SPTESSSASVSPVAKVSKFTLSS 2266 E GRW SP + S AS++ V S ++S Sbjct: 806 LSDAELGRWAELLSPLDESRASITSVTSFSPDDVAS 841 Score = 38.1 bits (87), Expect = 0.11 Identities = 59/223 (26%), Positives = 85/223 (38%), Gaps = 30/223 (13%) Query: 2196 IGGIQMVQARPGAHPTLLPGPTA---AWVSGFSGGGSDLTGAREAQERGRWSPTESSSAS 2252 IGG + ++ P A PT G ++ A SG G A+ SP +S + Sbjct: 65 IGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124 Query: 2253 VSPVAKVSKFTLSSEL-----EGGDYPKERERTGGGPGRPPDWTPHGTGAPAEP------ 2301 +S+E + + PK R G R GT +PA Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPK-RSALSAGARRDTSGPTPGTPSPAMARRSRAA 183 Query: 2302 -TPTHSPCTPPDTLPRPP-QGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAE 2359 T P P PRPP +G R + S + S + T P P+A R S+ G L Sbjct: 184 GTEVGLPRPAPSARPRPPTEGPRKSVSSA----SEHSTTEPSPAARR---RPSAGGGLQR 236 Query: 2360 ASARFPARTRNLSGEPRTRQDSPKPSGSGEPR--AHPHQPEDR 2400 ++R + + S P + PS G PR AHP QP+ + Sbjct: 237 PASR----SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 275 Score = 34.3 bits (77), Expect = 1.5 Identities = 34/131 (25%), Positives = 46/131 (35%), Gaps = 25/131 (19%) Query: 38 PGSGTAATQESPAQELLAPQP-FPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLP 96 P A P Q L +P FPG + S + PP+ PP+ A+ + P Sbjct: 516 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 575 Query: 97 QHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSF--------VAPGLHPQSQLLPSH 148 P +P +P +P PGP S +APG P PS Sbjct: 576 SPPASPTLQAPRRPP--------------TPGPDTSVSGPRLTLALAPGPPPPPSRSPS- 620 Query: 149 ASIIPPEDLPG 159 S + DL G Sbjct: 621 -STLSGPDLAG 630 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 80.1 bits (196), Expect = 2e-14 Identities = 229/1013 (22%), Positives = 345/1013 (34%), Gaps = 169/1013 (16%) Query: 739 SPGPSDAARNLPLESTKSPAEPSK-SVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEI 797 SP P + + P S +P P ++P E PT P P G + ++ + + Sbjct: 855 SPTPP-SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSM 913 Query: 798 SVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPP----PAPHGRSAHSLQPKLVRQPNI 853 + +SS +K+ + P G+ P P+PP P+P G A + PK P Sbjct: 914 T----SSSPKKARATPAPKGIPASPSPKGA-PTPPAATPPSPKGGPA-TPSPKWAPTPPA 967 Query: 854 QVPEIL----VTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLR 909 P T P T P P P+ P+ + T P PP K Sbjct: 968 ATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPT----PPAVTPPSPKGSP 1023 Query: 910 LAEMAQSSGESSFESSVPLSR-SPSQESNVSLSGSSRSASFERDDHGKAE-----APSPS 963 A + ++ P + SP+ + ++ +A+ G A AP+P Sbjct: 1024 AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP 1083 Query: 964 SDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVS------HSAHMTETRSKSFDYGS 1017 + P P G P P M +A+ SP A T + G Sbjct: 1084 AATPPSPKGGPATPSPKGAP----MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139 Query: 1018 LSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSS 1077 L+ T P AP P A P+ L+ PP PKG + P+++ Sbjct: 1140 LA-TPPPKGAPTTPAATPPSPK---------GGLATPP-------PKGAPTT----PAAT 1178 Query: 1078 KPSAKSSLSQIS---SAATSHGGPPGGKGPGQDRPPLG-PTVPYTEALQVFHHPVAQTPL 1133 PS K L+ S + T PP KG P G PT P A TP Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP------------AATPP 1226 Query: 1134 HEKPYL--PPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPL 1191 K L P P + P P +T + P + PP PP Sbjct: 1227 SPKGGLATPSPKGAPTTPAATPPSPKGGP---ATPPPKGAPTPPAATPPSLKGGLATPPH 1283 Query: 1192 P--LQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMP---YPTSSALSSGFFLPLQSQF 1246 P V+ P P P P PP P P P S S G P + Sbjct: 1284 KGAPNPAVVTP---------PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAP- 1333 Query: 1247 ALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLA 1306 P V P+ T P T S+ P+T S + PP A P+ P PP Sbjct: 1334 ---TPPAVTPPSPK-GTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSP 1389 Query: 1307 L--PACP----DTMVSLVVPV-----------RVQTNMPSYGSAMYTTLSQILVTQSQGS 1349 PA P D V+P+ R PS G ++ + + ++ + Sbjct: 1390 KRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT 1449 Query: 1350 SA-----------------TVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRA-F 1391 SA V P +EPP+ + + P+ + A Sbjct: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509 Query: 1392 PTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVK 1451 P+ VP T R+ + ++LS + + +T + ++ PA ++ +T K Sbjct: 1510 PSSPKEVPATPSSRRDPIAPTATLLS-KKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK 1568 Query: 1452 EEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKE 1511 E A+ + + E P +V ++ + P+ E+L + KE Sbjct: 1569 EAPATPSSK--EASSPPAVTPSTYKGAPSPK--------------ELLIPPAVTSPSPKE 1612 Query: 1512 IPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSSL 1571 P P T P E P P G P +TP S+K DS P + +++ Sbjct: 1613 APTPPAV-----TPPSPEKGPATPAPKGTPTSPPVTPSSLK--DSPTSPASVTCKMGATV 1665 Query: 1572 PLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWC 1631 P + PAK + T K+VL P+ +T ++ P ++SS + Sbjct: 1666 P-QASKGLPAK-KGPTALKEVLVAPAPESTPIIT-------APTRKGPQTKKSSATSPPI 1716 Query: 1632 I---SLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSR 1681 S N + +ST A LL QK S +T A H G L P S+ Sbjct: 1717 CPDPSAKNGSKGPLSTVAPAPLL-PVQKDSSKTAKGKDASHSPKGPLAPPESK 1768 Score = 73.6 bits (179), Expect = 2e-12 Identities = 197/854 (23%), Positives = 289/854 (33%), Gaps = 135/854 (15%) Query: 727 PPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEG------PTGFQPRTPKP 780 PP T P P P + +P P+ + PS +G P G P TP Sbjct: 1144 PPKGAPTTPAATPPSPKGGLATPPPKG--APTTPAATPPSPKGGLATPSPKG-APTTPAA 1200 Query: 781 GSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPP-------- 832 S G + K + L PS P A PSP Sbjct: 1201 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPP 1260 Query: 833 ---PAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDR--------PDTEPEPP---PKEP 878 P P + SL+ L P+ P V P P P PP P P Sbjct: 1261 KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP 1320 Query: 879 EKTEEFQWPQRSQTLAQL--PAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQES 936 + + P+ + T + P+ K P + + SS E P + +PS + Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380 Query: 937 NVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTV-PSHHPHAREMRRSASEQ 995 +++ S G A PSP D P ++ + P P R A+ Sbjct: 1381 GPAMTPPSPK-------RGPA-IPSPKGD----PTSPAVIPLSPKKAPATPVTREGAATP 1428 Query: 996 SPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPA--RVAPPERRKCFLVRQ-ASLS 1052 S +T K S GP+ P+ P V PP ++ +Q A+ S Sbjct: 1429 SKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSS 1488 Query: 1053 RPPESELEVAPKGRQESEEPQPSSSK--PSAKSS-----------LSQISSAATSHGG-- 1097 P ++ AP G PSS K P+ SS LS+ + A + Sbjct: 1489 SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548 Query: 1098 -PPGGKGPGQDRPPLGPT---VPYTEALQVFHHPVAQTPLHEKP-------YLPPPVSLF 1146 PP P + P PT P T + + P A TP K +PP V+ Sbjct: 1549 IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP 1608 Query: 1147 SFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQ------------ 1194 S + P A + +P S P P SL +P P Sbjct: 1609 SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQA 1668 Query: 1195 ----PTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGF------------ 1238 P P L + P P + P P+ SSA S Sbjct: 1669 SKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728 Query: 1239 ---------FLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPP 1289 LP+Q + G SH P K LAP S +P T + + LP Sbjct: 1729 PLSTVAPAPLLPVQKDSSKTAKGKDASHSP--KGPLAP--PESKASTPLTAAAFEKVLPK 1784 Query: 1290 VAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGS 1349 + S+AP+ PP++LP P + +L P + Q +PS + + S+ L + Sbjct: 1785 PESASVSAAPS--PPVSLPLAPSPVPTL--PPK-QQFLPSSPGLVLESPSKPLAPADEDE 1839 Query: 1350 SATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGT- 1408 + P EP S G V+ P +G+ PTP + PVT KG+ Sbjct: 1840 LLPLIPP---EPISGGVPFQSVLVNMPTPKSAGI------PVPTPSAKQPVT-KNNKGSG 1889 Query: 1409 --SLSSESILSLEGSSSTAGGSKRV-LSPAGSLELTMETQQQKRVKEEEASKADEKLELV 1465 S S ES+ LE ST +++ L+ A ++ ++ ++ E++A KA KL L Sbjct: 1890 TESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLR 1949 Query: 1466 KPCSVVLTSTEDGK 1479 + V + K Sbjct: 1950 QVTGVTRVTIRKSK 1963 Score = 72.8 bits (177), Expect = 4e-12 Identities = 121/516 (23%), Positives = 164/516 (31%), Gaps = 67/516 (12%) Query: 1900 PQPPDAPASGTE---ATRGSSVSEAERLTASSCSMS-SQSMPGLPWLGPAPLGSVEKDTG 1955 P P AP + +G ++ E T S ++ + P P AP S+ + Sbjct: 859 PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP 918 Query: 1956 SALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHV 2015 P P SPS + PP A S ++P P A+ PSP G Sbjct: 919 KKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPA 978 Query: 2016 DPG-RGMGALPCGS-PRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWS 2073 P +G P + P + P T P G P P P+ SP Sbjct: 979 TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP----------AVTPPSPKGSPAATPF 1028 Query: 2074 PGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFP-----PAPLPHKLLSRSP 2128 P A +PP + PP + GSP+A G P P PA K P Sbjct: 1029 PKGASTPPAATPP-----SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP 1083 Query: 2129 ETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTR 2188 K +PS P P ++ P + + + P T Sbjct: 1084 AATPPSPKGGPATPSPKGAPMPPAATPP--------------SPKGGLATPPHKGAPTTP 1129 Query: 2189 APCPLIPIGGI-----QMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRW 2243 A P P GG+ + P A P P P + G A +G Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATP---PSPKGGLATPPPKGAPTTPAATPPSPKGGL 1186 Query: 2244 SPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTP 2303 + A +P A T S G P + G P P P G A P+P Sbjct: 1187 ATPSPKGAPTTPAA-----TPPSPKGGLATPSPK----GAPTTPAATPPSPKGGLATPSP 1237 Query: 2304 THSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPS-----ATPPLDRSSSVGCLA 2358 +P TP T P P G + P +P P PS ATPP + + + Sbjct: 1238 KGAPTTPAATPPSPKGG----PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVT 1293 Query: 2359 EASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHP 2394 S + T G P +P PS G P P Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATP-PSPKGSPGTPP 1328 Score = 72.8 bits (177), Expect = 4e-12 Identities = 252/1153 (21%), Positives = 358/1153 (31%), Gaps = 188/1153 (16%) Query: 498 ESPKSSLYREPL-----SSHSEKTKPEQSLLSLQHPPSTAPPVPL-LRSHSMPSAACT-- 549 E+P S+ P ++ + K P S+ S + A P P + + P A T Sbjct: 884 ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP 943 Query: 550 ISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYSSEEPGPS 609 +TP P G T S + + T P K PA P G PS Sbjct: 944 AATPPSPKGGP------ATPSPKWAPTPPAAT--PPSPKGGPATPSPKGAPTPPAATPPS 995 Query: 610 SKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSEL 669 K + PS + P +T + KG Sbjct: 996 PKGGPATPSPKGAPTPPAVTPPSPKGSPA------------------------------- 1024 Query: 670 QIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPA 729 A P G T P A + P + TPL K P Sbjct: 1025 --ATPFPKGASTPPAATPPSPKGSPAA-------------TPLPKGAPTTPAATLPSPKG 1069 Query: 730 FESTKSQFGSPGPSDAARNLPLESTKSPAEPS-KSVPSLEGPTGFQPRTPKPGSGSESGK 788 +T S G+P P A P PA PS K P P P +PK G + K Sbjct: 1070 GPATPSLKGAPTPPAAT---PPSPKGGPATPSPKGAPM---PPAATPPSPKGGLATPPHK 1123 Query: 789 ERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSP----------------- 831 TT + L P P A PSP Sbjct: 1124 GAPTTPA-------ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1176 Query: 832 --PPAPHGRSAHSLQPKLVRQPNIQVPEI---LVTEEPDRPDTEPEPPPKEPEKTEEFQW 886 PP+P G A P P L T P T P P P+ Sbjct: 1177 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236 Query: 887 PQRSQT--LAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSV---PLSRSPSQESNVSLS 941 P+ + T A P+ K P + A ++ S + + P +P+ V Sbjct: 1237 PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA--VVTP 1294 Query: 942 GSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSH 1001 S + G AP+P + P P G+ P P + + SP + Sbjct: 1295 PSPKGGPATSPPKG---APTPPAATPPSPKGSPGTPPPKGAP----TPPAVTPPSPKGTP 1347 Query: 1002 SAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEV 1061 + T SK S GP+ PA A P+ P + P Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPTPPA--ATPSHKGGP---------AMTPPSPKRGPAIP 1396 Query: 1062 APKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGG--PPG------GKGPGQDRPPLGP 1113 +PKG S P S K + + +++ +A S G PP K P P GP Sbjct: 1397 SPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP 1456 Query: 1114 TVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLS 1173 P ++ P P ++P P V+ S + P + + + S Sbjct: 1457 ATPSSKGDPTL--PAVTPPSPKEPPAPKQVATSSSP---KKAPATPAPMGAPTLPAVIPS 1511 Query: 1174 SPYSMPPLPPSLFQ--APPLPL----QPTVLHPGQLHLPQLM--PHPANIPFRQPPSFLP 1225 SP +P P S AP L P L P + +P M P P P P P Sbjct: 1512 SPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAP 1571 Query: 1226 MPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAP--LATGSAGLSPSTEYSS 1283 + A S P + A P E +P TS +P T A PS E Sbjct: 1572 ATPSSKEASSPPAVTPSTYKGA---PSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628 Query: 1284 DIRLPPVAPPASSSAPTSAP--PLALPACPDTMVSLVVPVRVQTNMPSYGSAMY---TTL 1338 A PA PTS P P +L P + S+ + S G T L Sbjct: 1629 -------ATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTAL 1681 Query: 1339 SQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRV 1398 ++LV + S+ + P + P +K ++ + +G S P P Sbjct: 1682 KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP---- 1737 Query: 1399 PVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKA 1458 LP +K +S +++ + +S + G S LT ++ K E AS + Sbjct: 1738 --LLPVQKDSSKTAKG----KDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVS 1791 Query: 1459 DEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSD--PSDTKEIPPLP 1516 P S+ L + P K G +L S S P+D E+ PL Sbjct: 1792 AAP---SPPVSLPLAPSPVPTLPPKQQFLPSSPGL----VLESPSKPLAPADEDELLPLI 1844 Query: 1517 HPALSHGTAPGSEALKEYPQPSGK----PHRRGLTPLSVKKEDSKEQPDLPSLAPPSSLP 1572 P G P L P P P P++ + S + D P Sbjct: 1845 PPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVP----E 1900 Query: 1573 LSETSSRPAKSQE 1585 L E S A +Q+ Sbjct: 1901 LEEQDSTQATTQQ 1913 Score = 67.4 bits (163), Expect = 2e-10 Identities = 133/569 (23%), Positives = 187/569 (32%), Gaps = 97/569 (17%) Query: 1877 PSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSM 1936 PS + P P A + P P P + T +G+ + A L + ++ S+ Sbjct: 1017 PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSL 1076 Query: 1937 PGLPWLGPAPLGSVEKDTGSALSYKPVSPRR-PWSPSKEAGSRPPLARKHSLTKNDSSPQ 1995 G P A P SP+ P +PS + PP A S ++P Sbjct: 1077 KGAPTPPAAT---------------PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121 Query: 1996 RCSPAREPQASAPSPPG-LHVDPGRGMGALPCGSPRLQLSPL-TLCPLGRELAPRAHVLS 2053 P A+ PSP G L P +G P +P L T P G P A S Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1181 Query: 2054 KLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVL 2113 G P P+ +PT +P + P K LA P SP P Sbjct: 1182 PKGGLATPS-PKGAPT---------TPAATPPSPKGGLATP-SPKGAPTTPAAT------ 1224 Query: 2114 FPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHP----LSSRPFSALHDFHGHILA 2169 PP+P K +P +P + PS GPA P + P + G + Sbjct: 1225 -PPSP---KGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT 1280 Query: 2170 RTEENIFSHLPLHSQHLTRAPCPLI-----PIGGIQMVQARPGAHPTLLPGPTAAWVSGF 2224 P H AP P + P GG + P P+ G Sbjct: 1281 ----------PPHKG----APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT 1326 Query: 2225 SGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGP 2284 T + +PT ++ +P +K T SS+ EG P GGP Sbjct: 1327 PPPKGAPTPPAVTPPSPKGTPTLPAT---TPSSKGGPTTPSSK-EGPTPPAATPSHKGGP 1382 Query: 2285 GRPPDWTPHGTGAPAEPTPTHSPCTP------PDTLPRPPQGRRAAQSWS-----PRLES 2333 P P PA P+P P +P P P P R A + S P + Sbjct: 1383 AMTP---PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT 1439 Query: 2334 P----RAPTNPEPS---ATPPLDRSSSVGCLAEASARFPARTRNL--SGEPRTRQDSPKP 2384 P +AP P ATP ++ + S + P + + S P+ +P P Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499 Query: 2385 SGS--------GEPRAHPHQPEDRVPPNA 2405 G+ P+ P P R P A Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPIA 1528 Score = 59.3 bits (142), Expect = 4e-08 Identities = 133/558 (23%), Positives = 186/558 (33%), Gaps = 48/558 (8%) Query: 1877 PSSEAPPPGPPHALRADSSPILGPQPPDA----PASG--TEATRGSSVSEAERLTASSCS 1930 P+ A P P A SP P PP A P G T +G+ + A + Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139 Query: 1931 MSSQSMPGLPWLG----PAPLGSVE----KDTGSALSYKPVSPRRPWS-PSKEAGSRPPL 1981 +++ G P P+P G + K + + P SP+ + PS + P Sbjct: 1140 LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199 Query: 1982 ARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPG-RGMGALPCGSPRLQLS-PLTLC 2039 A S ++P P A+ PSP G P +G P +P P T Sbjct: 1200 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP 1259 Query: 2040 PLGRELAPRAHVLSKLEGTTDP---GLPRYSPTRRWSP--GQAESPPRSAPPGKWALAGP 2094 P G P A S G P G P + SP G A SPP+ AP A Sbjct: 1260 PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS 1319 Query: 2095 GSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSS 2154 S G P P + PP+P L P T S K +PS GP P ++ Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTPPSPKGTPTL---PATTPSS-KGGPTTPSSKEGPTPPAAT 1375 Query: 2155 RPFSALHDFHGHILARTEENIFSHLPLHSQHLTR-APCPLIPIGGIQMVQARPGAHPTLL 2213 G + +P T A PL P R GA Sbjct: 1376 PSHKG-----GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSK 1430 Query: 2214 PGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDY 2273 T V+ S + T A + S + + +V+P + ++ Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP-PAPKQVATSSS 1489 Query: 2274 PKERERTGGGPGRP--PDWTPHGTG-APAEPTPTHSPCTPPDTL----------PRPPQG 2320 PK+ T G P P P PA P+ P P TL P+ Sbjct: 1490 PKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALI 1549 Query: 2321 RRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQD 2380 A SP+ ++P PT E ATP +SS + ++ + + L P Sbjct: 1550 PPAMTVPSPK-KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP 1608 Query: 2381 SPKPSGSGEPRAHPHQPE 2398 SPK + + P P PE Sbjct: 1609 SPKEAPT-PPAVTPPSPE 1625 Score = 58.9 bits (141), Expect = 6e-08 Identities = 127/568 (22%), Positives = 180/568 (31%), Gaps = 100/568 (17%) Query: 1877 PSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSC--SMSSQ 1934 P E P P S + P P + PA T + A +T+SS + ++ Sbjct: 881 PPKETPTP----------SVVNLPFPKEGPA-----TPAPKQAPALSMTSSSPKKARATP 925 Query: 1935 SMPGLPWLGPAPLGSVEKDTGSALSYK--PVSPRRPWSPSKEAGSRPPLARKHSLTKNDS 1992 + G+P P+P G+ + S K P +P W+P+ PP A S + Sbjct: 926 APKGIP-ASPSPKGAPTPPAATPPSPKGGPATPSPKWAPT------PPAATPPSPKGGPA 978 Query: 1993 SPQRCSPAREPQASAPSPPGLHVDPG-RGMGALPCGSPRLQL-SPL-TLCPLGRELAPRA 2049 +P P A+ PSP G P +G P +P SP T P G P A Sbjct: 979 TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAA 1038 Query: 2050 HVLSKLEGTTDPGLPRYSPTR--------RWSPGQ-----AESPPRSAPPGKWALAGPGS 2096 S LP+ +PT + P A +PP + PP GP + Sbjct: 1039 TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP--KGGPAT 1096 Query: 2097 PSAGEHGPGLGLDPRVLFPPAPL------PHKLLSRSPETCASPWKAESRSPSCSPGPAH 2150 PS P P PP+P PHK +P K +P P Sbjct: 1097 PS-----PKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151 Query: 2151 PLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQAR----- 2205 P ++ P + + + P T A P P GG+ + Sbjct: 1152 PAATPP--------------SPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1197 Query: 2206 PGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERG-------RWSPTESSSASVSPV-- 2256 P A P P P + G A +G + +PT ++ SP Sbjct: 1198 PAATP---PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1254 Query: 2257 --------AKVSKFTLSSELEGG-DYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSP 2307 A L+GG P + PP +P + PT Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA 1314 Query: 2308 CTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPAR 2367 TPP P P + P P AT P + ++ PA Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA 1374 Query: 2368 TRNLSGEPRTRQDSPK-----PSGSGEP 2390 T + G P SPK PS G+P Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402 Score = 57.8 bits (138), Expect = 1e-07 Identities = 238/1118 (21%), Positives = 373/1118 (33%), Gaps = 209/1118 (18%) Query: 732 STKSQFGSPGP------SDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSE 785 S + G PGP S A + PL S + A P S PS T + P+ SG+ Sbjct: 33 SVTAALGQPGPTLPPPCSPAPQQCPL-SAANQASPFPS-PSTIASTPLEVPFPQSSSGTA 90 Query: 786 ----SGKERRTTSKE-ISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHG-RS 839 + E T I ++ + + P+ L+G A APH + Sbjct: 91 LPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPT-LKGTPSSSAPLALVALAPHSVQK 149 Query: 840 AHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAE 899 + + P L+ P P + V E P EP+ L ++P+E Sbjct: 150 SSAFPPNLLTSP----PSVAVAESGSVITLSAPIAPSEPKTN-----------LNKVPSE 194 Query: 900 KLPPKKKRLR------------LAEMAQ-SSGESSFESSVP---LSRSPSQESNVSLSGS 943 +P K + MA SG +S + P L+ + Q + ++S Sbjct: 195 VVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTIS-- 252 Query: 944 SRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPN---VS 1000 S + G P S L T L P +++A +P +S Sbjct: 253 --SVLISPQNPGSLSLKGPVSPPAALSLSTQSL------PVVTSSQKTAGPNTPPDFPIS 304 Query: 1001 HSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELE 1060 +H+ SF GS+ L G + P+ ++ P K V +S S+ Sbjct: 305 LGSHLAPLHQSSF--GSVQLLGQTGPSALSDPTV-------KTISVDHSSTGASYPSQRS 355 Query: 1061 VAPKGRQESEE-PQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPY-- 1117 V P +E P ++ P S+ + S +S P G L PT Sbjct: 356 VIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLIL 415 Query: 1118 -TEALQVFHHP-VAQTPLHEKPYLPPPVSLFSFQHLVQHEP---GQSPEFFSTQAMSSLL 1172 + +H+P VAQ P+ P LV P +P +T +++ + Sbjct: 416 KSSPNATYHYPLVAQMPVSSVGTTP----------LVVTNPCTIAAAPT--TTFEVATCV 463 Query: 1173 SSPYSMPPL-------PPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLP 1225 S P S P+ P +L AP P +P+ L +P P P + PS + Sbjct: 464 SPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVL 523 Query: 1226 MPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDI 1285 + +PT L + +P + A P + T L PL + SPS + +S Sbjct: 524 VKFPTQKDLQT---VPASLEGAPFSPAQAGLTTKKDPTVL-PLVQAAPKNSPSFQSTSSS 579 Query: 1286 RLPPVAPPASSSAPTSAPPLALPACPDTMVS--------LVVPVRVQTNMPSYGSAMYTT 1337 P++P A+ + + PL + +M S V+ S G + ++ Sbjct: 580 PEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSS 639 Query: 1338 L---------------SQILVTQSQGSS-----------ATVALPKFEEPPSKGTTV--- 1368 L + + T ++G+S TV+L P +GT Sbjct: 640 LITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLP 699 Query: 1369 ---CGADVHEVGPGPSG---------LSEEQSRAFPTPYLRVPVTLPERKGTSLSSESIL 1416 ++ V P P L+ E ++ P+P L T P K Sbjct: 700 LVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTK---------- 749 Query: 1417 SLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTE 1476 ++G S T+ L+P S T + +SK P + ++ + Sbjct: 750 KVDGISHTS-----ALAPVASSPKECPT-EDSGASATASSKGTLTYLADSPSPLGVSVSP 803 Query: 1477 DGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEY-- 1534 KRP + G+ G + +LSS P E LP +LS + S A Sbjct: 804 QTKRP-PTKKGSAGPD----TPIGNLSS-PVSPVEASFLPENSLSFQGSKDSPATTHSPT 857 Query: 1535 -PQPSGKPHRRGLTPLSVK------KED----------SKEQPDLPSLAPPSSLPLSETS 1577 P P G P +TPLS K KE KE P P AP + LS TS Sbjct: 858 PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP--APKQAPALSMTS 915 Query: 1578 SRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNP 1637 S P K++ K + PS K + + + P Sbjct: 916 SSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK------------WAP 963 Query: 1638 NLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPE 1697 P + + + T AT P P+ G PS P P V+P Sbjct: 964 TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAP------TPPAVTPP 1017 Query: 1698 GQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEG 1735 K + P P S +G PA + +G Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKG 1055 Score = 49.7 bits (117), Expect = 3e-05 Identities = 97/385 (25%), Positives = 148/385 (38%), Gaps = 65/385 (16%) Query: 1055 PESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPT 1114 P E P QE +PQ ++ S+LS T+ G PG P PP P Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALS-----VTAALGQPGPTLP----PPCSPA 52 Query: 1115 ---VPYTEALQVFHHP----VAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQA 1167 P + A Q P +A TPL E P+ P S + L G +PE + Sbjct: 53 PQQCPLSAANQASPFPSPSTIASTPL-EVPF--PQSSSGTALPL-----GTAPE--APTF 102 Query: 1168 MSSLLSSPYSMPPLPPSLFQAPPL---PLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFL 1224 + +L+ P S P +L A P+ L+ T L L L PH PP+ L Sbjct: 103 LPNLIGPPIS----PAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLL 158 Query: 1225 PMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSD 1284 P P+ + SG + L + A P + +++L ++ + + P G+ SP S+ Sbjct: 159 TSP-PSVAVAESGSVITLSAPIA---PSEPKTNLNKVPSEVVPNPKGTP--SPPCIVST- 211 Query: 1285 IRLPPVAPPAS---------SSAPTSAPPLALPACPDTMVSLVV-----PVRVQTNMPSY 1330 + V P AS + PT+ +A P DT +S V+ P + P Sbjct: 212 VPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVS 271 Query: 1331 GSAMYTTLSQIL--VTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVG-------PGPS 1381 A + +Q L VT SQ ++ P F P S G+ + G GPS Sbjct: 272 PPAALSLSTQSLPVVTSSQKTAGPNTPPDF--PISLGSHLAPLHQSSFGSVQLLGQTGPS 329 Query: 1382 GLSEEQSRAFPTPYLRVPVTLPERK 1406 LS+ + + + P ++ Sbjct: 330 ALSDPTVKTISVDHSSTGASYPSQR 354 Score = 49.3 bits (116), Expect = 5e-05 Identities = 119/507 (23%), Positives = 186/507 (36%), Gaps = 82/507 (16%) Query: 1877 PSSEAPPPGPPHALRADSSPILGP-QPPDAPASGTEATRGSSVSEAERLTASSCSMSSQS 1935 P S P P +SP + P P APA+ ++ S+ + + +S + Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445 Query: 1936 MPGL--PWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSS 1993 P P GPA S T A++ P SP+ P +P + A S SS Sbjct: 1446 APATSAPKGGPATPSSKGDPTLPAVT--PPSPKEPPAPKQVATS--------------SS 1489 Query: 1994 PQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRE----LAPRA 2049 P++ +PA AP+ P + + + A P S R ++P T L ++ LAP+ Sbjct: 1490 PKK-APATPAPMGAPTLPAVIPSSPKEVPATP-SSRRDPIAP-TATLLSKKTPATLAPKE 1546 Query: 2050 HVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLD 2109 ++ P PT + +P S S+PP G+PS E Sbjct: 1547 ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE-------- 1598 Query: 2110 PRVLFPPAPLPHKLLSRSPETCASPWKAESRSPS---CSPGPAHPLSSRPFSALHDFHGH 2166 +L PPA + S SP+ +P SP +P P +S P + Sbjct: 1599 --LLIPPA-----VTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVT-------- 1643 Query: 2167 ILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSG 2226 P + +P + G + QA G GPTA Sbjct: 1644 -------------PSSLKDSPTSPASVTCKMGATVPQASKGL--PAKKGPTAL-KEVLVA 1687 Query: 2227 GGSDLTGAREAQERGRWSPTESSSASVSPVA------KVSKFTLSSELEGGDYPKERERT 2280 + T A R + T+ SSA+ P+ SK LS+ P +++ + Sbjct: 1688 PAPESTPIITAPTR-KGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSS 1746 Query: 2281 GGGPGRPPDWTPHGTGAPAEPTPTHSPCTP---PDTLPRPPQGRRAAQSWSPRLESPRAP 2337 G+ +P G AP E + +P T LP+P +A SP + P AP Sbjct: 1747 KTAKGKDASHSPKGPLAPPE-SKASTPLTAAAFEKVLPKPESASVSAAP-SPPVSLPLAP 1804 Query: 2338 TNPEPSATPPLD-RSSSVGCLAEASAR 2363 +P P+ P SS G + E+ ++ Sbjct: 1805 -SPVPTLPPKQQFLPSSPGLVLESPSK 1830 Score = 48.9 bits (115), Expect = 6e-05 Identities = 127/558 (22%), Positives = 180/558 (32%), Gaps = 109/558 (19%) Query: 1877 PSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSM 1936 P A P G +S P + + A + V E T +S++ Sbjct: 649 PLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENC 708 Query: 1937 PGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARK-------HSLTK 1989 P + P+P + L+ P P+ SPS PP +K +L Sbjct: 709 P----VAPSPQNTCAPLATLVLA--PEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAP 762 Query: 1990 NDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRA 2049 SSP+ C P + ASA + +G SP PLG ++P+ Sbjct: 763 VASSPKEC-PTEDSGASATAS-------SKGTLTYLADSPS---------PLGVSVSPQT 805 Query: 2050 HVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLD 2109 +G+ P P + + SP +A P ++ + G A H P Sbjct: 806 KRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS----LSFQGSKDSPATTHSPT---- 857 Query: 2110 PRVLFPP----APLPHKLLSRSPETCASPWKAESRSPSC------SPGPAHPLSSRPFSA 2159 PP AP P + SP+ P K E+ +PS GPA P + + Sbjct: 858 -----PPSPKGAPTPSAVTPLSPKGVTLPPK-ETPTPSVVNLPFPKEGPATPAPKQAPA- 910 Query: 2160 LHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAA 2219 L + S +A P G + A P P P P AA Sbjct: 911 -------------------LSMTSSSPKKARATPAPKG----IPASPS--PKGAPTPPAA 945 Query: 2220 WVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERER 2279 GG A +W+PT ++ SP K T S + Sbjct: 946 TPPSPKGG--------PATPSPKWAPTPPAATPPSP--KGGPATPSPKGAPTPPAATPPS 995 Query: 2280 TGGGPGRPPDWTPHGTGAP---AEPTPTHSPC---------TPPDTLPRPPQGRRAAQSW 2327 GGP P +P G P P+P SP TPP P P+G AA Sbjct: 996 PKGGPATP---SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052 Query: 2328 SPRLESPRAPTNPEPS---ATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKP 2384 + A T P P ATP L + + S + T + G P +P P Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP-P 1111 Query: 2385 SGSGEPRAHPHQPEDRVP 2402 S G PH+ P Sbjct: 1112 SPKGGLATPPHKGAPTTP 1129 Score = 38.5 bits (88), Expect = 0.080 Identities = 195/950 (20%), Positives = 295/950 (31%), Gaps = 97/950 (10%) Query: 5 QSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAP-QPFPGPS 63 + + T +G P KG + + P G T + + +P P P GP+ Sbjct: 919 KKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPA 978 Query: 64 SVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVD 123 + +G+ PK P S P+ TP ++P P+ GS Sbjct: 979 TPSPKGAPTPPAATPPSPKGGPATPS------PKGAPTPPAVTPPSPK----GSP----- 1023 Query: 124 PMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRP----SQVSLK--PTE 177 P P G+ P P S S A+ P+ P P +P P + SLK PT Sbjct: 1024 AATPFPKGASTPPAATPPSPK-GSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP 1082 Query: 178 EAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYK 237 A P + P A K + + P P K L Sbjct: 1083 PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT 1142 Query: 238 HRKSHAHRIKAGLA-SGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPA 296 A A S GG P P P G +T S + T PA Sbjct: 1143 PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTT---PA 1199 Query: 297 ELSPRPKQPLLS---SGLYSSGSHSSSHERCSLSQSS-----TAQSLEDPPPFVEPSSEH 348 P PK L + G ++ + + + L+ S T + P P P++ Sbjct: 1200 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP 1259 Query: 349 PL-SHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKG--STESGYFSRSESAEQQVS 405 P + P K L K + P KG +T + + A S Sbjct: 1260 PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS 1319 Query: 406 P---PNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQ----PLLPLSTEDKPSLVPLSVPR 458 P P T A + T L AT+ P P S E P + P Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP--PAATPS 1377 Query: 459 TQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHS--EKT 516 + +T + + + D P LS + ++P + + RE ++ S + T Sbjct: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK---KAPATPVTREGAATPSKGDLT 1434 Query: 517 KPEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHS 576 P + +SL+ P+T+ P P+ + P P S + + + S Sbjct: 1435 PPAVTPVSLKKAPATSAP------KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSS 1488 Query: 577 SHVFTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDTASKPS---DEVEPKESELTKKTK 633 S K+ PA P+G S K+ + PS D + P + L+KKT Sbjct: 1489 SP---------KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP 1539 Query: 634 KGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHE 693 L K + + KK K+ A P S + P S + Sbjct: 1540 ATLAPKEALIPPAMTVPSPKKTPAIPTPKE------APATPSSKEASSPPAVTPSTYKGA 1593 Query: 694 PWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFESTKSQFGSPGPSDAARNLPLES 753 P + + T +P K P +T + G+P + +S Sbjct: 1594 PSPKELLIPPAVT---SPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDS 1650 Query: 754 TKSPA-----------EPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQH 802 SPA + SK +P+ +GPT + P S T Sbjct: 1651 PTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPES---TPIITAPTRKGPQTK 1707 Query: 803 TSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAP----HGRSAHSLQPKLVRQPNIQVPEI 858 SS PS G PL+ P P ++A + + PE Sbjct: 1708 KSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPES 1767 Query: 859 LVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRL 908 + E P E P S LA P LPPK++ L Sbjct: 1768 KASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFL 1817 Score = 35.4 bits (80), Expect = 0.68 Identities = 76/352 (21%), Positives = 120/352 (34%), Gaps = 46/352 (13%) Query: 1867 EEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPP-DAPASGTEATRGSSVSEAERLT 1925 E + +++ SS P P + A + P + P P + PA T ++R ++ L Sbjct: 1477 EPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPA--TPSSRRDPIAPTATLL 1534 Query: 1926 ASSCSM----------------SSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPW 1969 + S + P +P AP K+ S + P + + Sbjct: 1535 SKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG-- 1592 Query: 1970 SPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSP 2029 +PS + PP S + + P P+ E + P+P G P P Sbjct: 1593 APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP-------PVTPS 1645 Query: 2030 RLQLSPLT----LCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAP 2085 L+ SP + C +G + + L +G T +P +P +P R P Sbjct: 1646 SLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTP-IITAPTRKGP 1704 Query: 2086 PGKWALAGP----GSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRS 2141 K + A PSA G P PAPL L + + + K S S Sbjct: 1705 QTKKSSATSPPICPDPSAKNGSKG----PLSTVAPAPL---LPVQKDSSKTAKGKDASHS 1757 Query: 2142 PSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPL 2193 P P +S P +A +L + E S P L AP P+ Sbjct: 1758 PKGPLAPPESKASTPLTAA--AFEKVLPKPESASVSAAPSPPVSLPLAPSPV 1807 Score = 31.6 bits (70), Expect = 9.8 Identities = 36/147 (24%), Positives = 48/147 (32%), Gaps = 31/147 (21%) Query: 34 SVPYPGSGTAA-----------TQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPK 82 ++P+P G A T SP + P P P+S +G+ PK Sbjct: 892 NLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK 951 Query: 83 RPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQS 142 P S P+ TP +P P+ P P P G+ P P S Sbjct: 952 GGPATPS------PKWAPTPPAATPPSPKG----------GPATPSPKGAPTPPAATPPS 995 Query: 143 QLLPSHASIIP-PEDLPGVPKVFVPRP 168 P P P+ P P V P P Sbjct: 996 ---PKGGPATPSPKGAPTPPAVTPPSP 1019 >gi|49087132 sal-like 2 [Homo sapiens] Length = 1007 Score = 78.6 bits (192), Expect = 7e-14 Identities = 116/429 (27%), Positives = 171/429 (39%), Gaps = 103/429 (24%) Query: 18 RKRLTKGEAIQTSVSSSVP--YPGSGTAATQESPAQELLAP-QPFPGPSSVLREGSQEKT 74 R+ L G QT + + P PG+GTA++ + P L +P +P ++ S + Sbjct: 205 RQVLLLGSLGQTVGAPASPSELPGTGTASSTK-PLLPLFSPIKPVQTSKTLASSSSSSSS 263 Query: 75 GQQQKPPKRPPIEASVHI-----SQLP--------QHPLTPAFMSPGKPEHLLEGSTWQL 121 + PK +A H+ SQ P H TPA P L GST QL Sbjct: 264 SSGAETPK----QAFFHLYHPLGSQHPFSAGGVGRSHKPTPA------PSPALPGSTDQL 313 Query: 122 VDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPT----E 177 + +P L PS ++ + L G + S LKP E Sbjct: 314 I-----------ASPHL-----AFPSTTGLLAAQCL-GAARGLEATASPGLLKPKNGSGE 356 Query: 178 EAHKKERKP-QKPG-KYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNL 235 ++ + P +KPG ++ C++C++ S LQ H+RSHTGERPY C CG F T+ NL Sbjct: 357 LSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNL 416 Query: 236 YKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGES---------TDSEE 286 H H HR E YPH ++M P E + S + E Sbjct: 417 KVH--FHRHR-----------EKYPH-VQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAE 462 Query: 287 ETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSS 346 E +AT G E ++PL++S S + S + LS S+ + P F Sbjct: 463 EEAATPGGGVE-----RKPLVASTTALSATESLT----LLSTSAGTATAPGLPAF----- 508 Query: 347 EHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSP 406 + + ++ E K DE PGS+GS SG S + Q+S Sbjct: 509 --------------NKFVLMKAVEPKNKADENT--PPGSEGSAISGVAESSTATRMQLSK 552 Query: 407 PNTNAKSYA 415 T+ S+A Sbjct: 553 LVTSLPSWA 561 Score = 45.8 bits (107), Expect = 5e-04 Identities = 20/49 (40%), Positives = 25/49 (51%) Query: 194 CQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242 C C R + P L+ H H GERP+ C CG +F T+ NL H H Sbjct: 633 CVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGH 681 Score = 45.4 bits (106), Expect = 7e-04 Identities = 61/249 (24%), Positives = 86/249 (34%), Gaps = 41/249 (16%) Query: 1766 PSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHS-------------KKCQE 1812 P L+ H H RP+ CK C AF T+GNL H S KK Sbjct: 643 PRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTN 702 Query: 1813 TGVLEE----------------LEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSD 1856 L++ L G + + + G+ + + Q + Sbjct: 703 AVTLQQHVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEEL 762 Query: 1857 SDLDEDEDEDEEE---SQDELSRPSSEAPPPGPPHAL--RADSSPILGPQPPDAPASGTE 1911 S+ +E+EDE+EEE +D L+ SE+ G A+ R DS G + + Sbjct: 763 SEEEEEEDEEEEEDVTDEDSLAGRGSES---GGEKAISVRGDSEEASGAE-EEVGTVAAA 818 Query: 1912 ATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKP---VSPRRP 1968 AT G + E+ T S L P GS G KP SP Sbjct: 819 ATAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASA 878 Query: 1969 WSPSKEAGS 1977 +P EA S Sbjct: 879 LTPEGEATS 887 Score = 43.9 bits (102), Expect = 0.002 Identities = 20/49 (40%), Positives = 26/49 (53%) Query: 1752 GKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800 G++ C C S L+ H+R+HT RPY C C F T+GNL H Sbjct: 371 GRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVH 419 Score = 40.4 bits (93), Expect = 0.021 Identities = 40/136 (29%), Positives = 58/136 (42%), Gaps = 21/136 (15%) Query: 1811 QETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDE----- 1865 +E EE E EE D +DS GSE+ E S DS+ S +E+ Sbjct: 760 EELSEEEEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVAAAA 819 Query: 1866 ---DEEESQDELSRPSSEAPPPGP-----PHALRADSSPILG-------PQPPDAPASG- 1909 E +S ++ ++ SS PPP P P + SS +LG P+ +PAS Sbjct: 820 TAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASAL 879 Query: 1910 TEATRGSSVSEAERLT 1925 T +SV+ E L+ Sbjct: 880 TPEGEATSVTLVEELS 895 Score = 38.9 bits (89), Expect = 0.062 Identities = 109/442 (24%), Positives = 159/442 (35%), Gaps = 78/442 (17%) Query: 507 EPLSSHSEKTKP--EQSLLSLQHPPSTAPPVPLLRS-HSMPSAACTISTPHHPFRGSYSF 563 EP + E T P E S +S STA + L + S+PS A + T H GS+ F Sbjct: 518 EPKNKADENTPPGSEGSAISGVAESSTATRMQLSKLVTSLPSWA--LLTNHFKSTGSFPF 575 Query: 564 DDHITDSEALSHSSHVFTSHPRMLKRQPAIELP--LGGEYSSEEPGPSSKDTASKPSDEV 621 + A + + RQ A+ + G ++ P PSS +S P+ V Sbjct: 576 PYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSS-ASSGPNQCV 634 Query: 622 E-------PKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKP 674 P+ L G + ++C +CG + R N AH + A P Sbjct: 635 ICLRVLSCPRALRLHYGQHGGERP----FKCKVCGRAFSTRGNLRAHFVGH-----KASP 685 Query: 675 ISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFESTK 734 + ++ P +K Q + LG + P + G +E + +ST Sbjct: 686 AARAQNSCPICQKKFTNAVTLQQHVRMHLGGQI---PNGGTALPEGGGAAQENGSEQSTV 742 Query: 735 SQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTS 794 S GS + + P E E E G GSESG E Sbjct: 743 SGAGSFPQQQSQQPSPEEELSEEEEEEDE----EEEEDVTDEDSLAGRGSESGGE----- 793 Query: 795 KEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQ 854 K ISV + DS E+ SG E E +A A G+ S K +Q ++ Sbjct: 794 KAISV--------RGDS-EEASGAEEEVGTVA-----AAATAGKEMDS-NEKTTQQSSL- 837 Query: 855 VPEILVTEEPDRPDTEPEPPPKEPEKT------EEFQWPQRSQTLAQLPAEKLPPK---- 904 P PD+ +P P E + EE P+RS + PA L P+ Sbjct: 838 -------PPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSS----PASALTPEGEAT 886 Query: 905 ----KKRLRLAE-MAQSSGESS 921 + L L E M + GESS Sbjct: 887 SVTLVEELSLQEAMRKEPGESS 908 Score = 38.9 bits (89), Expect = 0.062 Identities = 41/158 (25%), Positives = 66/158 (41%), Gaps = 13/158 (8%) Query: 1659 KETYTMATAPHPEAGRLVPSSSRKPRMTEVHLP----SLVSPEG-QKDLARVEKEEERRG 1713 +E T+A A AG+ + S+ + + + + P SL P+ ++ + V +E G Sbjct: 810 EEVGTVAAAA--TAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGG 867 Query: 1714 EPEEDA-PASQ---RGEPARIKIFEGGYKSNEEYVYVRGRGRGKYVCEECGIRCKKPSML 1769 +PE + PAS GE + + E E G + CE CG + L Sbjct: 868 KPERSSSPASALTPEGEATSVTLVEE-LSLQEAMRKEPGESSSRKACEVCGQAFPSQAAL 926 Query: 1770 KKHIRTHTDVRP-YVCKHCHFAFKTKGNLTKHMKSKAH 1806 ++H +TH P + C C F + L KHM H Sbjct: 927 EEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHH 964 Score = 36.6 bits (83), Expect = 0.31 Identities = 23/99 (23%), Positives = 41/99 (41%), Gaps = 5/99 (5%) Query: 154 PEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPG----KYICQYCSRPCAKPSVLQK 209 PE P S+ EE +E ++PG + C+ C + + L++ Sbjct: 869 PERSSSPASALTPEGEATSVTLVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEE 928 Query: 210 HIRSHTGERP-YPCGPCGFSFKTKSNLYKHRKSHAHRIK 247 H ++H E P + C C F ++ L KH H+++ Sbjct: 929 HQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQ 967 Score = 35.4 bits (80), Expect = 0.68 Identities = 60/260 (23%), Positives = 92/260 (35%), Gaps = 55/260 (21%) Query: 2057 GTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPP 2116 G++ P P + P RR PG + +A G+ + G G Sbjct: 103 GSSVPTDPTWGPERRGEES----------PGHFLVAATGTAAGGGGG------------- 139 Query: 2117 APLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEE-NI 2175 L+ SP+ A+P ES +P P P P + H +I EE + Sbjct: 140 ------LILASPKLGATPLPPES-----TPAPPPPPPPPPPPGVGSGHLNIPLILEELRV 188 Query: 2176 FSHLPLHSQHLTRAPC-PLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGA 2234 +H +T C ++ +G + P A P+ LPG +G + L Sbjct: 189 LQQRQIHQMQMTEQICRQVLLLGSLGQTVGAP-ASPSELPG------TGTASSTKPLLPL 241 Query: 2235 REAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGP-GRPPDWTPH 2293 + + S T +SS+S S S G + PK+ P G ++ Sbjct: 242 FSPIKPVQTSKTLASSSSSS-----------SSSSGAETPKQAFFHLYHPLGSQHPFSAG 290 Query: 2294 GTGAPAEPTPTHSPCTPPDT 2313 G G +PTP SP P T Sbjct: 291 GVGRSHKPTPAPSPALPGST 310 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 75.5 bits (184), Expect = 6e-13 Identities = 355/1711 (20%), Positives = 570/1711 (33%), Gaps = 320/1711 (18%) Query: 482 DSVKPRR-----SSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVP 536 +S PRR S + S K +R P K+K ++ S ST P Sbjct: 201 ESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSR----STTPAPK 256 Query: 537 LLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELP 596 R+H SA S+ S + S S+ T + R P+ Sbjct: 257 SRRAHRSTSADSASSSD---------------TSRSRSRSAAAKTHTTALAGRSPSPASG 301 Query: 597 LGGEYSS--EEPG------PSSKDTASK-PSDEVEPKESELTKKTKKGLKTKGVIYECNI 647 GE + EPG PSS +TA+K PS E K+ + +K+ Sbjct: 302 RRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSAT------------- 348 Query: 648 CGARYKKRDNYEAHKKYYCSELQIAKPISAGTHT-SPEA-EKSQIEHEPWSQMMHYKLGT 705 R + + E P+ A H SP+ + + EP + Sbjct: 349 -------RPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEP--------VNP 393 Query: 706 TLELTPLRKRRKEKS-------LGDEEEPPAFESTK------SQFGSPGPSDAA------ 746 E +P R R KS E PP+ + TK S SP P+ A Sbjct: 394 PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREI 453 Query: 747 RNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSF 806 + P +S + P+ R+ P + RT +K + + Sbjct: 454 SSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQW 513 Query: 807 EKSDSLEQ-PSGLEGEDKPLAQFPSPP---------------PAPHGRSAHSLQPKLVRQ 850 +S S ++ + + ++ P P A GRS HS P + Sbjct: 514 RRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRS-HSRSPATRGR 572 Query: 851 PNIQVPEILV---TEEPDRPDTEPEPPPKEPEK--TEEFQWPQRSQTLAQLPAEKLPPKK 905 + P + P R + P + + T + RS+T A+ + P + Sbjct: 573 SRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVR 632 Query: 906 KRLRLAEMAQSSGESSFESSVPLSRSPSQ----------ESNVSLSGSSRSASFERDDHG 955 +R R A+ SG S + RS S+ + SG SRS + R Sbjct: 633 RRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRS 692 Query: 956 KAEAP-------------SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVS-- 1000 ++ P S P+ G + + RRS S SP + Sbjct: 693 RSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKS 752 Query: 1001 -----HSAHMTETRSKSFDYGSL--SLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSR 1053 S ++ RSK+ SL SL+G S P PP R + S S Sbjct: 753 RISSRRSRSLSSPRSKAKSRLSLRRSLSGSS---PCPKQKSQTPPRRSR-------SGSS 802 Query: 1054 PPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGP 1113 P+++ P+ + S P P K +K+ Q S+++ H G P Q Sbjct: 803 QPKAKSRTPPRRSRSSSSPPP---KQKSKTPSRQSHSSSSPHPKVKSGTPPRQGS----- 854 Query: 1114 TVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAM--SSL 1171 + +E+ P S F E PE S S Sbjct: 855 --------------ITSPQANEQSVTPQRRSCF--------ESSPDPELKSRTPSRHSCS 892 Query: 1172 LSSP----YSMPPLPPSLFQAPPLPLQPTVLHPGQL-HLPQLMPHPANIPFRQPPSFLPM 1226 SSP S PP + P P ++ P Q H P P+ + R P Sbjct: 893 GSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRS 952 Query: 1227 PYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIR 1286 P S+ S LP S P ++K P + S +SP + + Sbjct: 953 VSPCSNVESR--LLPRYSHSGSSSPDT------KVKPETPPRQSHSGSISPYPKVKAQTP 1004 Query: 1287 LPPVAPPASSSAPTSAPPLAL-PACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQ 1345 P + S P +L +CP SL + V+++ P G + + S L Q Sbjct: 1005 PGPSLSGSKSPCPQEKSKDSLVQSCPG---SLSLCAGVKSSTPP-GESYFGVSSLQLKGQ 1060 Query: 1346 SQGS--------SATVALPKFEEP---------PSKGTTVCGADVHEVGPGPSGLSEEQS 1388 SQ S S V E P P G + + V E+ S + +++ Sbjct: 1061 SQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELA-SRSPIRQDRG 1119 Query: 1389 RAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQK 1448 +P L+ ++ PE+ S S +++ S+S G S+ LE T E++++ Sbjct: 1120 EFSASPMLKSGMS-PEQSRFQSDSSSYPTVD-SNSLLGQSR--------LE-TAESKEKM 1168 Query: 1449 RVKEEEASKADEKLELVK----------PCSVVLTSTEDGKRPEKSHLGNQGQGRRELEM 1498 + +E + A + K S+V T E+S G+ + + + Sbjct: 1169 ALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSA 1228 Query: 1499 LSSLSSDPSDTKEIPPLPHPA---LSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKED 1555 L + S D + + PA LSH ++ E + S + R L++ + Sbjct: 1229 LPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQ 1288 Query: 1556 SK---EQPDLPSLA-----PPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWC 1607 S+ E ++PS+A P S E S+ P + + L T N + Sbjct: 1289 SQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFS 1348 Query: 1608 ----------YLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKV 1657 +LN ++ + +S+ +G S +P+ KA +S S Q + Sbjct: 1349 SEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPD---AVEKAGMS---SNQSI 1402 Query: 1658 SKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEE 1717 S +P +A PS R S SPE + L R R G Sbjct: 1403 S--------SPVLDAVPRTPSRERSS--------SASSPEMKDGLPRTPSRRSRSGSSPG 1446 Query: 1718 DAPASQRGEPARIKIFEGGYKSNEEYVYVRGRGRG--------KYVCEECGIRCKKPSML 1769 S G P+R + G ++ RGR K + + R + PS Sbjct: 1447 LRDGS--GTPSRHSL-SGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSP 1503 Query: 1770 KKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDL 1829 + + + T R KT +S++ S QE V +E + D Sbjct: 1504 ELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSS--QELDVKPSASPQERSESDS 1561 Query: 1830 FQDSEGREGSEAVEEHQFSDLEDSDSDSDLD----------EDEDEDE-----EESQDEL 1874 DS+ + + + + + DS S L E +D+ + D Sbjct: 1562 SPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSS 1621 Query: 1875 SRPSSEAPPPGPPHALRADSSPILGPQP---------PDAPASGTEATRGSSVSEAERLT 1925 P + AP P + SS GP P P+ P A RGS S + Sbjct: 1622 PEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTK 1681 Query: 1926 ASSCSM--SSQSMPGLPWLGPAPLGSVEKDTGSALSYKP-VSPRRPWSPSKEAGSRPPLA 1982 + + SS+S P L A L + S+ + PR SPS + + Sbjct: 1682 SRTPPRRRSSRSSPELT--RKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKS 1739 Query: 1983 RKHSLTKNDSSPQRCSPAREPQASAPSPPGL 2013 R ++ SSP+ + +R ++ +P P GL Sbjct: 1740 RSSRRRRSASSPRTKTTSRRGRSPSPKPRGL 1770 Score = 69.7 bits (169), Expect = 3e-11 Identities = 230/1093 (21%), Positives = 360/1093 (32%), Gaps = 216/1093 (19%) Query: 16 SPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTG 75 SPR + +++ S+S S P P Q P R GS + Sbjct: 764 SPRSKAKSRLSLRRSLSGSSPCP-----------------KQKSQTPPRRSRSGSSQPKA 806 Query: 76 QQQKPPKR-------PPIEASV------HISQLPQHPLTPAFMSPGKPEHLLEGSTWQLV 122 + + PP+R PP + S H S P HP + P + + Q V Sbjct: 807 KSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSP-HPKVKSGTPPRQGSITSPQANEQSV 865 Query: 123 DPMR-------PGPSGSFVAPGLHPQSQLLPSHA-SIIPPEDLPG-----VPKVFV---- 165 P R P P P H S P S PP P PKV Sbjct: 866 TPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISP 925 Query: 166 ----------PRPSQVSLKPTEEAHKKER-----KPQKPGKYICQYCSRPCAKPSVLQKH 210 P PS+V+ + T + + + +Y S P K Sbjct: 926 RQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPP 985 Query: 211 IRSHTGE-RPYPC-------GPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMG------- 255 +SH+G PYP GP K+ K + S L+ G Sbjct: 986 RQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPP 1045 Query: 256 GEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPA-----ELSPRPKQPLLSSG 310 GE Y G+ ++ G+ P T S E + S P+ + SP+ + SS Sbjct: 1046 GESY-FGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSP 1104 Query: 311 LYSSGSHSS-SHERCSLSQSSTAQSLEDPPP--FVEPSSEHPLSHKPEDTHTIKQKLALR 367 + S S +R S S +S P F SS +P D++++ + L Sbjct: 1105 VTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTV----DSNSLLGQSRLE 1160 Query: 368 LSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQ 427 +E K + P + +T S + + SP + + ++F R Sbjct: 1161 TAESK-----EKMALPPQEDATAS-----PPRQKDKFSPFPVQDRPESSLVFKDTLRTPP 1210 Query: 428 RTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPR 487 R +S + T+++ S +P S +++E VV+ SE +P Sbjct: 1211 RERSGAGSSPE------TKEQNSALPTSSQDEELME-----------VVEKSE----EPA 1249 Query: 488 RSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAA 547 LS SS S+ E SS + +P SL +L S A L + +PS A Sbjct: 1250 GQILSHLSSELKEMSTSNFE--SSPEVEERPAVSL-TLDQSQSQAS----LEAVEVPSMA 1302 Query: 548 CTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYSSEEPG 607 + PH F+ + L P E G G Sbjct: 1303 SSWGGPH-------------------------FSPEHKELSNSPLRENSFGSPLEFRNSG 1337 Query: 608 PSSKDTASKPSDEVE-----PKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHK 662 P + + S EV+ P ++L +K + G + K Sbjct: 1338 PLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQST----RSSGHSSSELSPDAVEK 1393 Query: 663 KYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLG 722 S I+ P+ +P E+S P ++ L TP R+ R S G Sbjct: 1394 AGMSSNQSISSPVLDAVPRTPSRERSSSASSP-------EMKDGLPRTPSRRSRSGSSPG 1446 Query: 723 --DEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPS-KSVPSLEGPTGFQPRTP- 778 D P+ S SPG D R ++ + P K++P P P +P Sbjct: 1447 LRDGSGTPSRHSLSGS--SPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPE 1504 Query: 779 ---------KPGSGSESGKERRT-------------TSKEISVIQHTSSFEKSDSLEQPS 816 + SGSES +++T +S+E+ V S E+S+S P Sbjct: 1505 LNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPD 1564 Query: 817 GLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVR---QPNIQVPEILVTEEPDRPDTEPEP 873 PL Q +P S L P+ R P ++ D+ PEP Sbjct: 1565 SKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEP 1624 Query: 874 PPKEPE---------KTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFES 924 P + + + P + + + + PPK + R ++SS E +S Sbjct: 1625 KAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRG--SRSSPEPKTKS 1682 Query: 925 SVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPH 984 P P + S+ S +R A R + +P S P+ + ++ P Sbjct: 1683 RTP----PRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEK 1738 Query: 985 AREMRRSASEQSP 997 +R RR S SP Sbjct: 1739 SRSSRRRRSASSP 1751 Score = 62.8 bits (151), Expect = 4e-09 Identities = 129/543 (23%), Positives = 192/543 (35%), Gaps = 124/543 (22%) Query: 604 EEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKK 663 E P P S S S PK+ + KK +G +++ + ++ + KK Sbjct: 166 EPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSE---------SSSPRRERKKSSKKK 216 Query: 664 YYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGD 723 + SE + K H SP + + + K + TP K R+ Sbjct: 217 KHRSESESKK----RKHRSPTPKSKRKSKDK-------KRKRSRSTTPAPKSRR------ 259 Query: 724 EEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSG 783 A ST + S SD +R+ S+S + T R+P P SG Sbjct: 260 -----AHRSTSAD--SASSSDTSRS-----------RSRSAAAKTHTTALAGRSPSPASG 301 Query: 784 ---------SESG--KERRTTSKEISVIQHTSSFEKSD------SLEQPSGLEGEDKPLA 826 SE G +R +S E + Q +S +E D S +PS Sbjct: 302 RRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGP 361 Query: 827 QFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEP-----PPKEPEKT 881 + P+P P R S QP L P +++EP P +E P PPK PEK Sbjct: 362 EPPAPTPLLAERHGGSPQP-LATTP--------LSQEPVNPPSEASPTRDRSPPKSPEKL 412 Query: 882 EEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLS 941 PQ S +E PP + +++ A SS ES + +P +S S Sbjct: 413 -----PQSSS------SESSPPSPQPTKVSRHASSSPESPKPAP-----APGSHREISSS 456 Query: 942 GSSRSASFERDDHGKAEAPSPSSDM------RPKPLGTHMLTVPSHHPHAR----EMRRS 991 +S++ S R K+ + +PS M G P+ H+R + RRS Sbjct: 457 PTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRS 516 Query: 992 ASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASL 1051 S Q S S RS+S P P +R +RR R S Sbjct: 517 RSAQRWGRSRSP-QRRGRSRS----------PQRPG----WSRSRNTQRRG----RSRSA 557 Query: 1052 SRPPESELEVAPKGRQESEEP----QPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQD 1107 R A +GR S P + S P+ + S S+ + S P +G + Sbjct: 558 RRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRS 617 Query: 1108 RPP 1110 R P Sbjct: 618 RTP 620 Score = 57.0 bits (136), Expect = 2e-07 Identities = 139/597 (23%), Positives = 199/597 (33%), Gaps = 109/597 (18%) Query: 1838 GSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPI 1897 GS + Q S L S D +L E ++ EE + LS SSE + +SSP Sbjct: 1217 GSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNF---ESSPE 1273 Query: 1898 LGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA 1957 + +P T S S+A SM+S W GP Sbjct: 1274 VEERP------AVSLTLDQSQSQASLEAVEVPSMASS------WGGP------------- 1308 Query: 1958 LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDP 2017 + P SP +E PL ++S S + + P L DP Sbjct: 1309 -HFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDP 1367 Query: 2018 GRGM---GALPCGSPRLQLSPLTLCPLGR-----------ELAPRAHVLSKLEGTTDP-- 2061 M G +LSP + G + PR + + P Sbjct: 1368 SLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEM 1427 Query: 2062 --GLPRYSPTRRWSPGQAES-PPRSAPPGKWALAG--------PGSPSAGEHGPGLGLDP 2110 GLPR +P+RR G + S P + +L+G P +PS G +P Sbjct: 1428 KDGLPR-TPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEP 1486 Query: 2111 RVLFPPAPLPHKLLSRSPET---CASPWKAESRSPSCSPGPA---HPLSSRPFS-ALHDF 2163 + L P P P SPE C +P + S S S PL R S + + Sbjct: 1487 KAL-PQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQEL 1545 Query: 2164 HGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSG 2223 A +E S S+ TR P ++R G+ P + S Sbjct: 1546 DVKPSASPQERSESDSSPDSKAKTRTPL---------RQRSRSGSSPEVDSK------SR 1590 Query: 2224 FSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGG 2283 S S + E +++ R +P S + SP K P+ Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRA--------LPRRSRSGSSS 1642 Query: 2284 PGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPS 2343 GR P +P G+ + E +P H PP+ R A R S +P S Sbjct: 1643 KGRGP--SPEGSSS-TESSPEH-----------PPKSRTA------RRGSRSSPEPKTKS 1682 Query: 2344 ATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDR 2400 TPP RSS AR R+R+ S P TR +P P P +P ++ Sbjct: 1683 RTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTP-PRHRRSPSVSSPEPAEK 1738 Score = 55.8 bits (133), Expect = 5e-07 Identities = 71/268 (26%), Positives = 104/268 (38%), Gaps = 31/268 (11%) Query: 871 PEPPPKEPEKTEEFQWPQRSQTLAQLPAEKL-PPKKKRLRLAEMAQSSGESS--FESSVP 927 P P + T E + P S + Q P++ L PP + + R + S +S + P Sbjct: 2410 PPSAPSQSRMTSE-RAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTP 2468 Query: 928 LSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPS---SDMRPKPL--GTHMLTVPSHH 982 ++ S S S + +S + D +G P+P SD+ P G + + Sbjct: 2469 VAGSQSLSSGAVATTTSSAG----DHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAAL 2524 Query: 983 PHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPA---RVAPPE 1039 A+E RRS+S S + S S+ + + S S GS S + PV P RV P Sbjct: 2525 QPAKE-RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583 Query: 1040 RRKCFLVRQASLSRPPE-----------SELEVAPKGRQESEEPQPSSSKPSAKSSLSQI 1088 VR+ RPPE S + S SSS S+ SS S Sbjct: 2584 PAPKEAVREG---RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2640 Query: 1089 SSAATSHGGPPGGKGPGQDRPPLGPTVP 1116 SS+++S P GP P P P Sbjct: 2641 SSSSSSSSPSPAKPGPQALPKPASPKKP 2668 Score = 54.3 bits (129), Expect = 1e-06 Identities = 84/338 (24%), Positives = 116/338 (34%), Gaps = 73/338 (21%) Query: 743 SDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQH 802 S A + + S +P P V TG Q P + + KERR++S S Sbjct: 2485 SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQ--PSALAALQPAKERRSSSSSSSSSSS 2542 Query: 803 TSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTE 862 +SS S S SG D + P P E+ + Sbjct: 2543 SSSSSSSSSSSSSSGSSSSDSEGSSLPVQP------------------------EVALKR 2578 Query: 863 EPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSF 922 P P P PKE + P E P K+KR + + SS SS Sbjct: 2579 VPS-----PTPAPKEAVREGR-------------PPEPTPAKRKRRSSSSSSSSSSSSSS 2620 Query: 923 ESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHH 982 SS S S S S+ S S SS S+S +PSP+ +P P P Sbjct: 2621 SSSSSSSSSSSSSSSSSSSSSSSSSS---------SSPSPA---KPGPQALPKPASPKKP 2668 Query: 983 PHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRK 1042 P RRS S + P S + ++RS S+ S P+P P + Sbjct: 2669 PPGE--RRSRSPRKPIDS----LRDSRSLSY-----SPVERRRPSPQPSPRDQQSSSSER 2717 Query: 1043 CFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS 1080 Q SR P + K R+E+ P+P + S Sbjct: 2718 GSRRGQRGDSRSP------SHKRRRETPSPRPMRHRSS 2749 Score = 46.2 bits (108), Expect = 4e-04 Identities = 78/325 (24%), Positives = 118/325 (36%), Gaps = 57/325 (17%) Query: 863 EPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSF 922 +P R E + P EP K R + ++ P K KKK+ + G S Sbjct: 152 DPQRRAREAKQPAPEPPKPYSLV---RESSSSRSPTPKQKKKKKK-------KDRGRRS- 200 Query: 923 ESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHH 982 ESS P R ++S+ S S S +R K +P+P S + K + Sbjct: 201 ESSSP--RRERKKSSKKKKHRSESESKKR----KHRSPTPKSKRKSKDKKRKRSRSTTPA 254 Query: 983 PHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRK 1042 P +R RS S S + S ++ + +RS + + +L G S P+P + Sbjct: 255 PKSRRAHRSTSADSASSSDTSR-SRSRSAAAKTHTTALAGRS-PSPAS------------ 300 Query: 1043 CFLVRQASLSRPPESELEVAPKGR---QESEEPQPSSSKPSAKSSLSQISSAATSHGGPP 1099 R E + + G Q P+ ++ +PS+ S P Sbjct: 301 ---------GRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRP- 350 Query: 1100 GGKGPGQDRPPLGPTVPYTEALQVFHH-----PVAQTPLHEKPYLPPPVSLFSFQHLVQH 1154 P +R GP P L H P+A TPL ++P PP + Sbjct: 351 ---SPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEA----SPTRDR 403 Query: 1155 EPGQSPEFFSTQAMSSLLSSPYSMP 1179 P +SPE Q+ SS S P P Sbjct: 404 SPPKSPEKL-PQSSSSESSPPSPQP 427 Score = 44.3 bits (103), Expect = 0.001 Identities = 139/624 (22%), Positives = 224/624 (35%), Gaps = 102/624 (16%) Query: 1809 KCQETGVLEELEAEEGTSDDLFQDSEGR--EG-SEAVEEHQFSDLEDSDSDSDLDEDEDE 1865 +C+ G+LE L + T + Q + G +G + +HQ + + ++ + S + Sbjct: 2129 RCRSPGMLEPLGSSR-TPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRI------ 2181 Query: 1866 DEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLT 1925 + +S ++ PP L A S + P P + + A S + A + Sbjct: 2182 --ALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAA---S 2236 Query: 1926 ASSCSMSSQSMPGLPWL----------GPAPLGSVEKDTGSALSYKPVS-PRRPWSPSKE 1974 A++ +++S P +P A + T A S ++ PR P +P+ Sbjct: 2237 AAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVN 2296 Query: 1975 -AGSRPPLARKH-SLTKNDSSPQRC---SPAREPQASAPSPPGLHVDPGRGMGALPCGSP 2029 AG+R P A SLT + + P S +R PQA P+ L V P P Sbjct: 2297 LAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQA--PASANL-VGPRSAHATAPVNIA 2353 Query: 2030 RLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTR---RWSPGQAESPPRSAPP 2086 + + L P A A LS T P +P + R R SP + PP Sbjct: 2354 GSRTAA-ALAPASLTSARMAPALSGAN-LTSPRVPLSAYERVSGRTSPPLLDRARSRTPP 2411 Query: 2087 GKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSP-ETCASPWKAESRSPSCS 2145 +PS R+ AP P + ++P ++ P + + RSP S Sbjct: 2412 S--------APSQS----------RMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPS 2453 Query: 2146 PGPAHP----LSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQM 2201 + P + +A T + H + S P P +P + Sbjct: 2454 AFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLS-----VPAPGVPHSDVGE 2508 Query: 2202 VQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSK 2261 A GA P AA R + S + SSS+S S + S Sbjct: 2509 PPASTGAQQ---PSALAALQPAKE---------RRSSSSSSSSSSSSSSSSSSSSSSSSS 2556 Query: 2262 FTLSSELEGGDYPKERERTGGGPGRPPDWTPH-----GTGAPAEPTPTHSPCTPPDTLPR 2316 + SS+ EG P + E R P TP G P EPTP Sbjct: 2557 GSSSSDSEGSSLPVQPE---VALKRVPSPTPAPKEAVREGRPPEPTPA------------ 2601 Query: 2317 PPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPR 2376 + RR++ S S S + ++ S++ SSS + +S+ P+ + + Sbjct: 2602 -KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP-GPQAL 2659 Query: 2377 TRQDSPKPSGSGEPRAH-PHQPED 2399 + SPK GE R+ P +P D Sbjct: 2660 PKPASPKKPPPGERRSRSPRKPID 2683 Score = 43.5 bits (101), Expect = 0.003 Identities = 265/1375 (19%), Positives = 446/1375 (32%), Gaps = 197/1375 (14%) Query: 276 PTEGEST-DSEEETSATSGHPAELSPRPKQPLLSSGLYS-----SGSHSSSHERC----- 324 P+ G S DS E A P S P P L++ + SGS SS ++ Sbjct: 1473 PSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTP 1532 Query: 325 --SLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTIKQKLALRL-SERKKVIDEQAFL 381 S+S ++Q L D P P P+ + L R S +D ++ L Sbjct: 1533 LGQRSRSGSSQEL-DVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRL 1591 Query: 382 SPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLL 441 SP SRS S+ + P R R + +S +P Sbjct: 1592 SPRR---------SRSGSSPEVKDKP----------------RAAPRAQSGSDSSPEPKA 1626 Query: 442 PLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRSSMESPK 501 P P ++PR +K + ++E P +S +RR S SP+ Sbjct: 1627 P---------APRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPE 1677 Query: 502 -SSLYREPLSSHSEKTKPE---QSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHHPF 557 + R P S ++ PE ++ LS + +++ P R+ + ++S+P P Sbjct: 1678 PKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPE-PA 1736 Query: 558 RGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDTASKP 617 S S S +S T R P+ + P G + S S ++ Sbjct: 1737 EKSRS-------SRRRRSASSPRTKTTSRRGRSPSPK-PRGLQRSRSR---SRREKTRTT 1785 Query: 618 SDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKPISA 677 S+ T + ++ +++ + G+ Y R S + + S Sbjct: 1786 RRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGR--SR 1843 Query: 678 GTHTSPEAEKSQIEHEPWSQMMHYKLGTT----LELTPLRKRRKEKSLGDEEEPPAFEST 733 TS + +S+ PW + T TPL RR+ +S P + + Sbjct: 1844 TPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRS---RTSPVSRRRS 1900 Query: 734 KSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGK--ERR 791 +S+ +R P+ +S S++ P + + T + S S + RR Sbjct: 1901 RSRTSVTRRRSRSRASPVSRRRSR---SRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRR 1957 Query: 792 TTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPS---PPPAPHGRSAHSLQPKLV 848 + S+ V + S S + S P+ + S P RS P Sbjct: 1958 SRSRTPPVTRRRSRSRTSPITRRRS--RSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTR 2015 Query: 849 RQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAE---KLPPKK 905 R+ + P + R P P K +RS++ A L Sbjct: 2016 RRSRSRTPPAIRRRSRSRT---PLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSP 2072 Query: 906 KRLRLAEMAQSSGESSFESSVPLSR--SPSQESNVSLSGSSRSASFERDDHGKAEAPSPS 963 +R + SS + S ++ P +R S S+ V+L+ SSR + F R Sbjct: 2073 PAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALN-SSRMSCFSRPSMSPTPLDRCR 2131 Query: 964 SDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGP 1023 S +PLG+ + M + P+ ++ + E ++S +L+LT Sbjct: 2132 SPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTS-VPENHAQSRI--ALALTAI 2188 Query: 1024 SAPAPVAPPARVAPPERRKCFLVRQASLSRP-PESELEVAPKGRQESEEPQPSSSKPSAK 1082 S PP+ A R + + P P L AP S P S++ + Sbjct: 2189 SLGTARPPPSMSAAG-----LAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLA 2243 Query: 1083 S--------------SLSQISSAATSHGGP-----PGGKGPGQDRPPLGPTVPYT----- 1118 S S + ++AA + P P R P P V Sbjct: 2244 SARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTP 2303 Query: 1119 EALQVFHHPVAQTP--------LHEKPYLPPPVSLFSFQHLVQHEP----------GQSP 1160 AL + TP P P +L + P +P Sbjct: 2304 AALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAP 2363 Query: 1161 EFFSTQAMSSLLSSP-YSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQ 1219 ++ M+ LS + P +P S ++ P +L + P P + + + Sbjct: 2364 ASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSER 2423 Query: 1220 PPSFLPMPYPTS---SALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLA----TGS 1272 PS P+S A S P Q Q +P + P+A S Sbjct: 2424 APS------PSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSS 2477 Query: 1273 AGLSPSTEYSSDIR-LPPVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYG 1331 ++ +T + D + V P + PP + A + ++ + P + + + S Sbjct: 2478 GAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSS 2537 Query: 1332 SAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAF 1391 S+ ++ S + S SS + + V V P P E Sbjct: 2538 SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE 2597 Query: 1392 PTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVK 1451 PTP R + +S SS S S SSS++ S S Sbjct: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------------------ 2639 Query: 1452 EEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEML---SSLSSDPSD 1508 +S + KP L K+P ++ R+ ++ L SLS P + Sbjct: 2640 -SSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSP-RKPIDSLRDSRSLSYSPVE 2697 Query: 1509 TKEIPPLPHPALSHGT---------------APGSEALKEYPQPSGKPHRRGLTP 1548 + P P P + +P + +E P P HR +P Sbjct: 2698 RRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752 Score = 42.7 bits (99), Expect = 0.004 Identities = 148/691 (21%), Positives = 219/691 (31%), Gaps = 118/691 (17%) Query: 1764 KKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQETGVLEELEAEE 1823 KK S KKH R+ ++ + + K K K +S++ + + A+ Sbjct: 210 KKSSKKKKH-RSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADS 268 Query: 1824 GTSDDLFQDSEGREGSEAVEEHQ--FSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEA 1881 +S D S R S A + H + S + E + E RPSS Sbjct: 269 ASSSDT---SRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSS-- 323 Query: 1882 PPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPW 1941 P A + SSP + D ATR S E S + P Sbjct: 324 ----PETATKQPSSPY---EDKDKDKKEKSATRPSPSPERS-------STGPEPPAPTPL 369 Query: 1942 LGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAG---SRPPLARKHSLTKNDSSPQRCS 1998 L GS + + LS +PV+P SP+++ S L + S + SPQ Sbjct: 370 LAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTK 429 Query: 1999 PAREPQASAPSP-----PGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLS 2053 +R +S SP PG H R + + P R GR ++H Sbjct: 430 VSRHASSSPESPKPAPAPGSH----REISSSPTSKNRSH---------GRAKRDKSH--- 473 Query: 2054 KLEGTTDPGLPRYSPTRRWSPGQAESP-------PRSAPPGKWALAGPGSP----SAGEH 2102 ++P+RR G++ SP RS P K + SP S Sbjct: 474 -----------SHTPSRRM--GRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQ 520 Query: 2103 GPGLGLDPRVLFPPAPLPHKLLSRSPE----TCASPWKAESRSPSCSPGPAHPLS----S 2154 G P+ + SRSP+ + + + RS S G +H S Sbjct: 521 RWGRSRSPQ---------RRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRG 571 Query: 2155 RPFSALHDFHGHILART--EENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTL 2212 R S G +RT S P + +R P + R + Sbjct: 572 RSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPV 631 Query: 2213 LPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGD 2272 + + SG T AR + R R S S +P + + + G Sbjct: 632 RRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGR 691 Query: 2273 YPKERERTGGG-------PGRPPDWTPHGTGAPAEPTPTHSPC----------TPPDTLP 2315 R G GR TP G + + + P+ Sbjct: 692 SRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKK 751 Query: 2316 RPPQGRRAAQSWSPRLE-----------SPRAPTNPEPSATPPLDRSSSVGCLAEASARF 2364 RR+ SPR + S +P + S TPP RS S +A +R Sbjct: 752 SRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPP-RRSRSGSSQPKAKSRT 810 Query: 2365 PARTRNLSGEPRTRQDSPKPSGSGEPRAHPH 2395 P R S P +Q S PS + PH Sbjct: 811 PPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH 841 Score = 42.0 bits (97), Expect = 0.007 Identities = 50/204 (24%), Positives = 70/204 (34%), Gaps = 22/204 (10%) Query: 1831 QDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHAL 1890 + S S + S S S D + Q E++ +P P P A+ Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590 Query: 1891 RADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSV 1950 R P P +S + ++ SS S + ++SS S SS S + Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650 Query: 1951 EKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSP 2010 G KP SP++P P E SR P RK + DS SP E + +P P Sbjct: 2651 PAKPGPQALPKPASPKKP--PPGERRSRSP--RKPIDSLRDSRSLSYSPV-ERRRPSPQP 2705 Query: 2011 PGLHVDPGRGMGALPCGSPRLQLS 2034 SPR Q S Sbjct: 2706 -----------------SPRDQQS 2712 Score = 40.8 bits (94), Expect = 0.016 Identities = 113/518 (21%), Positives = 175/518 (33%), Gaps = 65/518 (12%) Query: 1908 SGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKP---VS 1964 S T RG S S +ER S S P + + + S + S+ K +S Sbjct: 715 SRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLS 774 Query: 1965 PRRPWS---PSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGM 2021 RR S P + S+ P R S + + R P R +S+P P P R Sbjct: 775 LRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQS 834 Query: 2022 GALPCGSPRLQLSP-----LTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQ 2076 + P+++ P E + S E + DP L +P+R G Sbjct: 835 HSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGS 894 Query: 2077 AESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWK 2136 + +S+ P + + + SP P+V A + + S S + SP + Sbjct: 895 SPPRVKSSTPPRQSPSRSSSP-----------QPKV---KAIISPRQRSHSGSSSPSPSR 940 Query: 2137 AESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPI 2196 SR+ P SR S + +L R +SH S P Sbjct: 941 VTSRTT--------PRRSRSVSPCSNVESRLLPR-----YSHSGSSSPDTKVKP------ 981 Query: 2197 GGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGARE--AQERGRWSPTESSSASVS 2254 R ++ P P V + G L+G++ QE+ + S +S S+S Sbjct: 982 ----ETPPRQSHSGSISPYPK---VKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLS 1034 Query: 2255 PVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTL 2314 A V T E G + + G PD + + + SP + Sbjct: 1035 LCAGVKSSTPPGESYFGVSSLQLK---GQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQ 1091 Query: 2315 PRPPQGRRAAQSWSPRL--ESPRAPTNPEPSATPPL--DRSSSVGCLAEASARFPARTRN 2370 P GR + S L SP E SA+P L S S+ +P N Sbjct: 1092 TSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSN 1151 Query: 2371 -LSGEPRTRQDSPKPSGSGEPR----AHPHQPEDRVPP 2403 L G+ R K + P+ A P + +D+ P Sbjct: 1152 SLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSP 1189 Score = 40.0 bits (92), Expect = 0.028 Identities = 66/291 (22%), Positives = 97/291 (33%), Gaps = 31/291 (10%) Query: 1877 PSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSM 1936 P ++ P P + +D S L Q P +G+++ +V+ M S Sbjct: 2441 PPAQDQPRSPVPSAFSDQSRCLIAQT--TPVAGSQSLSSGAVATTTSSAGDHNGMLSVPA 2498 Query: 1937 PGLPW--LGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSP 1994 PG+P +G P + + + + +P RR S S + S + S + + S Sbjct: 2499 PGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGS 2558 Query: 1995 -----QRCSPAREPQAS---APSP---PGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGR 2043 + S +P+ + PSP P V GR P R S Sbjct: 2559 SSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSS-------SS 2611 Query: 2044 ELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHG 2103 + + S ++ S + S + S P A PG AL P SP G Sbjct: 2612 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG 2671 Query: 2104 PGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSS 2154 PR P L S SP E R PS P P SS Sbjct: 2672 ERRSRSPR-------KPIDSLRDSRSLSYSP--VERRRPSPQPSPRDQQSS 2713 Score = 37.4 bits (85), Expect = 0.18 Identities = 57/241 (23%), Positives = 79/241 (32%), Gaps = 20/241 (8%) Query: 1497 EMLSSLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQP-------SGKPHRRGLTPL 1549 E SS S P K+ S ++P E K + S K R TP Sbjct: 176 ESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPK 235 Query: 1550 SVKKEDSKEQPDLPSL--APPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWC 1607 S +K K++ S AP S TS+ A S + + S+ HTT Sbjct: 236 SKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG-- 293 Query: 1608 YLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATA 1667 P + + + S P+ P +TK S K K KE + Sbjct: 294 --RSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPS 351 Query: 1668 PHPEAGRLVPS-SSRKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGE 1726 P PE P + P + E H S + LA +E P E +P R Sbjct: 352 PSPERSSTGPEPPAPTPLLAERHGGS------PQPLATTPLSQEPVNPPSEASPTRDRSP 405 Query: 1727 P 1727 P Sbjct: 406 P 406 Score = 35.4 bits (80), Expect = 0.68 Identities = 128/636 (20%), Positives = 193/636 (30%), Gaps = 113/636 (17%) Query: 1796 NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSE---------------GREGSE 1840 ++ H + + +C E LEE+ E+G + Q+ G+E + Sbjct: 56 DILDHERKRRVELRCLE---LEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETP 112 Query: 1841 A-----VEEHQFSDLEDSDSD------SDLDEDEDEDEEESQDELSRPSSEAPPPGPPHA 1889 E HQ ++L + ++ D D + Q AP P P++ Sbjct: 113 GQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYS 172 Query: 1890 LRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGS 1949 L +SS P P + S S + R S + Sbjct: 173 LVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESE-------SK 225 Query: 1950 VEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDS-SPQRCSPAREPQASAP 2008 K K S + S+ P R H T DS S S +R A+A Sbjct: 226 KRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAK 285 Query: 2009 SPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSP 2068 + H G P R G AP + GTT P Sbjct: 286 T----HTTALAGRSPSPASGRR-----------GEGDAPFSE-----PGTTSTQRPSSPE 325 Query: 2069 TRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSP 2128 T P K A SP GP PPAP Sbjct: 326 TATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPE---------PPAP---------- 366 Query: 2129 ETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTR 2188 +P AE S P PLS P + + R+ LP S + Sbjct: 367 ----TPLLAERHGGSPQPLATTPLSQEPVNPPSE-ASPTRDRSPPKSPEKLPQSSSSESS 421 Query: 2189 APCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTES 2248 P P P + + P + P P P G +++ + ++ R Sbjct: 422 PPSPQ-PTKVSRHASSSPES-PKPAPAP---------GSHREISSSPTSKNRSHGRAKRD 470 Query: 2249 SSASVSPVAKVSKFTLSSELEGGDYPKERERT----GGGPGRPPDWTPHGTG-------A 2297 S S +P ++ + + + G + R RT G R P W + + Sbjct: 471 KSHSHTPSRRMGRSRSPATAKRG---RSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRS 527 Query: 2298 PAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCL 2357 P + SP P + R Q R ++S + R ++ AT RS + Sbjct: 528 PQRRGRSRSPQRPGWSRSRNTQRRGRSRS------ARRGRSHSRSPATRGRSRSRTPARR 581 Query: 2358 AEASARFPARTRNLSGEP-RTRQDSPKPSGSGEPRA 2392 + +R PAR R+ S P R R S P+ G R+ Sbjct: 582 GRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRS 617 Score = 34.3 bits (77), Expect = 1.5 Identities = 32/132 (24%), Positives = 45/132 (34%), Gaps = 22/132 (16%) Query: 2274 PKERERTGGGPG----RPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSP 2329 P ER GG P P P + A PT SP P+ LP+ + S P Sbjct: 368 PLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQP 427 Query: 2330 RLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGE 2389 S A ++PE P P R +S P ++ S + Sbjct: 428 TKVSRHASSSPESPKPAPA----------------PGSHREISSSPTSKNRS--HGRAKR 469 Query: 2390 PRAHPHQPEDRV 2401 ++H H P R+ Sbjct: 470 DKSHSHTPSRRM 481 Score = 33.9 bits (76), Expect = 2.0 Identities = 31/135 (22%), Positives = 47/135 (34%) Query: 274 EEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQ 333 ++P+ + +E ++S + S SS SSGS SS E SL Sbjct: 2516 QQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVA 2575 Query: 334 SLEDPPPFVEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGY 393 P P P PE T +++ + S + S S S+ S Sbjct: 2576 LKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2635 Query: 394 FSRSESAEQQVSPPN 408 S S S+ S P+ Sbjct: 2636 SSSSSSSSSSSSSPS 2650 Score = 32.7 bits (73), Expect = 4.4 Identities = 43/168 (25%), Positives = 60/168 (35%), Gaps = 17/168 (10%) Query: 2234 AREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPH 2293 +R A SS S S + T ++ L G R G G + Sbjct: 257 SRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTT 316 Query: 2294 GTGAPAEP-TPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSS 2352 T P+ P T T P +P + + + + A + P R+ T PEP A PL Sbjct: 317 STQRPSSPETATKQPSSPYEDKDKDKKEKSATR---PSPSPERSSTGPEPPAPTPL---- 369 Query: 2353 SVGCLAE--ASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPE 2398 LAE + P T LS EP + P + R+ P PE Sbjct: 370 ----LAERHGGSPQPLATTPLSQEP---VNPPSEASPTRDRSPPKSPE 410 Score = 32.3 bits (72), Expect = 5.8 Identities = 35/137 (25%), Positives = 54/137 (39%), Gaps = 23/137 (16%) Query: 3 PEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGP 62 P+++V+ + E +P KR + + +S SSS S ++++ S + + Sbjct: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSS---SSSSSSSSSSSSSSSSSSSSSSSSS 2642 Query: 63 SSVLREGSQEKTGQQQKP----PKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGS- 117 SS S K G Q P PK+PP P SP KP L S Sbjct: 2643 SSSSSSPSPAKPGPQALPKPASPKKPP-------------PGERRSRSPRKPIDSLRDSR 2689 Query: 118 --TWQLVDPMRPGPSGS 132 ++ V+ RP P S Sbjct: 2690 SLSYSPVERRRPSPQPS 2706 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 73.9 bits (180), Expect = 2e-12 Identities = 126/516 (24%), Positives = 177/516 (34%), Gaps = 111/516 (21%) Query: 815 PSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPD--TEPE 872 P+ GE P+ P AP S P ++QP Q P T + P T P+ Sbjct: 608 PAAATGEAAPVLTVQPAPQAPPAVSTPL--PLGLQQPQAQQPPQAPTPQAAAPPQATTPQ 665 Query: 873 PPP---KEPEKTEEFQWPQRSQT--LAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVP 927 P P PEK Q P + T L Q + P+++ + ++ S +SV Sbjct: 666 PSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQ--PLSAEGPHLSVPASVI 723 Query: 928 LSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHARE 987 +S P + + ++ A +P+P+ + P A Sbjct: 724 VSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQI----------------PAAAP 767 Query: 988 MRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVR 1047 ++ SP++ H A + ++ +P P PP+R PP R + Sbjct: 768 LKGPGPSSSPSLPHQAPLGDSPHLP------------SPHPTRPPSR--PPSRPQ----- 808 Query: 1048 QASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGP--- 1104 S+SRPP SE P P A +L I G PP P Sbjct: 809 --SVSRPP-------------SEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPT 853 Query: 1105 --GQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVS---LFSFQHLVQHEPGQS 1159 G +PPL P E PL P+LPP + + S P + Sbjct: 854 APGPPQPPLRPQSQPPEG-----------PLPPAPHLPPSSTSSAVASSSETSSRLPAPT 902 Query: 1160 PEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQ 1219 P F Q S P+ P PP+L L+P PA P Sbjct: 903 PSDFQLQFPPS--QGPHKSPTPPPTL---------------------HLVPEPAAPPPPP 939 Query: 1220 PPSF----LPMP-YPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAG 1274 P +F P P P AL F + S LQ PQ TSL PL + +A Sbjct: 940 PRTFQMVTTPFPALPQPKALLERFH-QVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAAS 998 Query: 1275 LSPSTEYSSDI-RLPPVAPPASSSAPTSAPPLALPA 1309 + S + S P AP + A T PPL LPA Sbjct: 999 VLVSGQAPSGTPTAPSHAPAPAPMAATGLPPL-LPA 1033 Score = 61.6 bits (148), Expect = 9e-09 Identities = 129/557 (23%), Positives = 198/557 (35%), Gaps = 110/557 (19%) Query: 1089 SSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKP--YLPP----- 1141 + AA++ G P G+ P P LG + P A V H TP+ KP LPP Sbjct: 310 AGAASAPTGTPSGQ-PLAVAPGLGSS-PLVPAPNVILHRTP-TPIQPKPAGVLPPKLYQL 366 Query: 1142 ---PVSLFSFQHLVQHEPGQSPE----------FFSTQAMSSLLSSPYSMPPLPPSLFQA 1188 P + +Q EPG P+ + +A +++ S + P L ++F+ Sbjct: 367 TPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQ 426 Query: 1189 PPL------PLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPL 1242 PP P QP PG L P + H N +S + + LP Sbjct: 427 PPATTTGAAPPQP----PGALSKPMSV-HLLN-------------QGSSIVIPAQHMLPG 468 Query: 1243 QSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSA 1302 Q+QF L PG LPQ ++L G + + + P+ + + P S Sbjct: 469 QNQFLL--PGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSL 526 Query: 1303 PPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQ----GSSATVALPKF 1358 P+ P ++ +Q P+ + + L TQSQ G +AT L Sbjct: 527 GPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGV 586 Query: 1359 EEPPS-----------------KGTTVCGADVHEVGPGPS-----------GLSEEQSR- 1389 PPS T A V V P P GL + Q++ Sbjct: 587 TLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQ 646 Query: 1390 --AFPTPYLRVP--VTLPE-RKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMET 1444 PTP P T P+ G + S E I+ + S+T + SL++ + Sbjct: 647 PPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSAT----PTAILTQDSLQMFLPQ 702 Query: 1445 QQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSS 1504 ++ ++ E L P SV++++ + P + +G G S S Sbjct: 703 ERSQQPLSAEGP------HLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQAS- 755 Query: 1505 DPSDTKEIP---------PLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKED 1555 P+ +IP P P+L H G P P+ P R P SV + Sbjct: 756 -PAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPP 814 Query: 1556 SKEQPDLPSLAPPSSLP 1572 S +P L PP + P Sbjct: 815 S--EPPLHPCPPPQAPP 829 Score = 51.6 bits (122), Expect = 9e-06 Identities = 129/524 (24%), Positives = 173/524 (33%), Gaps = 130/524 (24%) Query: 1884 PGPPHALRADSSPILGPQP-PDAP-ASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPW 1941 P P A +++P+L QP P AP A T G +A++ P Sbjct: 605 PATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQ----------------PP 648 Query: 1942 LGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAR 2001 P P + A + +P SP SP K +PP A ++ DS R Sbjct: 649 QAPTPQAAAPPQ---ATTPQP-SPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQER 704 Query: 2002 EPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDP 2061 Q + P L V + A P P +P T G L P+A Sbjct: 705 SQQPLSAEGPHLSVPASVIVSAPP---PAQDPAPATPVAKGAGLGPQA------------ 749 Query: 2062 GLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPG---SPSAGEHGPGLGLDPRVLFPPAP 2118 P + SP A P +AP L GPG SPS P LG P + P+P Sbjct: 750 ------PDSQASPAPAPQIPAAAP-----LKGPGPSSSPSLPHQAP-LGDSPHL---PSP 794 Query: 2119 LPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSH 2178 P + SR P SR S S P+ P Sbjct: 795 HPTRPPSRPP----------SRPQSVSRPPSEP--------------------------- 817 Query: 2179 LPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLL-PGPTAAWVSGFSGGGSDLTGAREA 2237 PLH +AP P +P GI ++Q + G P P PTA G + Sbjct: 818 -PLHPCPPPQAP-PTLP--GIFVIQNQLGVPPPASNPAPTAP------GPPQPPLRPQSQ 867 Query: 2238 QERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGA 2297 G P S + A S SS L P + + PP PH + Sbjct: 868 PPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPT-PSDFQLQF-----PPSQGPHKS-- 919 Query: 2298 PAEPTPTH---SPCTPPDTLPRPPQGRRAAQSWSPRLESPRA--------PT-----NPE 2341 P P H P PP P PP+ + + P L P+A P+ N Sbjct: 920 PTPPPTLHLVPEPAAPP---PPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKA 976 Query: 2342 PSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPS 2385 A S+S+G L +A + SG P +P P+ Sbjct: 977 GGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPA 1020 Score = 49.7 bits (117), Expect = 3e-05 Identities = 178/794 (22%), Positives = 272/794 (34%), Gaps = 143/794 (18%) Query: 735 SQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESG----KER 790 S FG G + A P + A S P + P RTP P +G K Sbjct: 305 SVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLY 364 Query: 791 RTTSKEISVIQHTSSFEKSDSL--EQP----------SGLEGEDKPLAQFPSPPPAPHGR 838 + T K + T + + +QP +G G++ L+ FP+P Sbjct: 365 QLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAP------- 417 Query: 839 SAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTE--------EFQWPQRS 890 +LQ + +QP P P +P P + + P ++ Sbjct: 418 ---ALQANVFKQP----PATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQN 470 Query: 891 Q-TLAQLPAEKLPPKKKRLR-------LAEMAQSSGESSFESSVPLSRSPSQESNVSLSG 942 Q L PA +LP + L LA A +G + P+ + + +SL Sbjct: 471 QFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIAN--PILTNQNLAGPLSLGP 528 Query: 943 SSRSASFERDDHGKAEAP----SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPN 998 S H + AP P+ P L L S A + + Sbjct: 529 VLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTL 588 Query: 999 VSHSAHMTETRSKSFDYGS-LSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPES 1057 + M T + + TG +AP PA APP ++S P Sbjct: 589 PPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPP-----------AVSTPLPL 637 Query: 1058 ELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPY 1117 L+ P+ +Q + P P ++ P ++ A+S P GQ P PT Sbjct: 638 GLQ-QPQAQQPPQAPTPQAAAPPQATTPQPSPGLASS----PEKIVLGQP-PSATPTAIL 691 Query: 1118 T-EALQVF-HHPVAQTPLH-EKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLL-- 1172 T ++LQ+F +Q PL E P+L P S+ + P Q P + A + L Sbjct: 692 TQDSLQMFLPQERSQQPLSAEGPHLSVPASVI----VSAPPPAQDPAPATPVAKGAGLGP 747 Query: 1173 ------SSPYSMPPLPPSL-FQAPPLPLQPTVLHPGQL----HLPQLMPHPANIPFRQP- 1220 +SP P +P + + P P++ H L HLP PHP P R P Sbjct: 748 QAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS--PHPTRPPSRPPS 805 Query: 1221 -----------PSFLPMPYPTSSALSSGFFL--------PLQSQFALQLPGDVESHL-PQ 1260 P P P P + G F+ P S A PG + L PQ Sbjct: 806 RPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQ 865 Query: 1261 IKTSLAPL--------ATGSAGLSPSTEYSSDIRLPPVA------PPASSSAPTSAPPLA 1306 + PL ++ S+ ++ S+E SS + P + PP+ + PP Sbjct: 866 SQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPT 925 Query: 1307 LPACPDTMVSLVVPVR----VQTNMPS--YGSAMYTTLSQI---LVTQSQGSSATVALPK 1357 L P+ P R V T P+ A+ Q+ ++ Q++ A A Sbjct: 926 LHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAP-- 983 Query: 1358 FEEPPSKG-TTVCGADVHEVGPGPSGLSEEQSRA---FPTPYLRVPVTLPERKGTSLSSE 1413 + S G T A V G PSG S A P +P LP S+ Sbjct: 984 -QTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNL 1042 Query: 1414 SILSLEGSSSTAGG 1427 L++ ++S+ G Sbjct: 1043 PTLNVAKAASSGPG 1056 Score = 47.4 bits (111), Expect = 2e-04 Identities = 109/431 (25%), Positives = 161/431 (37%), Gaps = 62/431 (14%) Query: 1021 TGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS 1080 TG +AP PA APP ++S P L+ P+ +Q + P P ++ P Sbjct: 612 TGEAAPVLTVQPAPQAPP-----------AVSTPLPLGLQ-QPQAQQPPQAPTPQAAAPP 659 Query: 1081 AKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTE-ALQVF-HHPVAQTPLH-EKP 1137 ++ A+S P GQ P PT T+ +LQ+F +Q PL E P Sbjct: 660 QATTPQPSPGLASS----PEKIVLGQP-PSATPTAILTQDSLQMFLPQERSQQPLSAEGP 714 Query: 1138 YLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTV 1197 +L P S+ + P Q P + A + L P S AP +P + Sbjct: 715 HLSVPASVI----VSAPPPAQDPAPATPVAKGAGLGP--QAPDSQASPAPAPQIPAAAPL 768 Query: 1198 LHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESH 1257 PG P L PH A P P LP P+PT P + Q + P + H Sbjct: 769 KGPGPSSSPSL-PHQA--PLGDSPH-LPSPHPTRPPSRP----PSRPQSVSRPPSEPPLH 820 Query: 1258 L---PQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTM 1314 PQ +L + L V PPAS+ APT+ P P P + Sbjct: 821 PCPPPQAPPTLPGIFVIQNQLG-------------VPPPASNPAPTAPGPPQPPLRPQSQ 867 Query: 1315 VSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKG---TTVCGA 1371 P+ ++P S+ + ++ T S+ + T + + + PPS+G + Sbjct: 868 PP-EGPLPPAPHLPP--SSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPP 924 Query: 1372 DVHEVGPGPSGLSEEQSRAF-----PTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAG 1426 +H V P P+ R F P P L P L ER S + + G + A Sbjct: 925 TLHLV-PEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAP 983 Query: 1427 GSKRVLSPAGS 1437 + L P S Sbjct: 984 QTSTSLGPLTS 994 Score = 47.0 bits (110), Expect = 2e-04 Identities = 73/296 (24%), Positives = 102/296 (34%), Gaps = 46/296 (15%) Query: 1867 EEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTA 1926 +E SQ LS PH S + P P PA T +G+ + + Sbjct: 702 QERSQQPLSAEG--------PHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQ 753 Query: 1927 SSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHS 1986 +S + + Q P GP P S + L SP P SRPP +R S Sbjct: 754 ASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLG---DSPHLPSPHPTRPPSRPP-SRPQS 809 Query: 1987 LTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELA 2046 +++ S P P PQA P+ PG+ V + P +P A Sbjct: 810 VSRPPSEPP-LHPCPPPQA-PPTLPGIFVIQNQLGVPPPASNP----------------A 851 Query: 2047 PRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPR-SAPPGKWALAGPGSPSAGEHGPG 2105 P T PG P+ + P + PP PP + A S P Sbjct: 852 P-----------TAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPA 900 Query: 2106 -LGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSAL 2160 D ++ FPP+ PHK + P P E +P P + + PF AL Sbjct: 901 PTPSDFQLQFPPSQGPHKSPTPPPTLHLVP---EPAAPPPPPPRTFQMVTTPFPAL 953 Score = 43.5 bits (101), Expect = 0.003 Identities = 110/528 (20%), Positives = 169/528 (32%), Gaps = 126/528 (23%) Query: 742 PSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKER-------RTTS 794 P + LPL + A+ P+ + Q TP+P G S E+ T Sbjct: 628 PPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATP 687 Query: 795 KEISVIQHTSSFEKSDSLEQPSGLEG-----------EDKPLAQFPSP-----------P 832 I F + +QP EG P AQ P+P P Sbjct: 688 TAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGP 747 Query: 833 PAPHGRSAHSLQPKLVRQPNIQVP----------EILVTEEPDRPDTEP-EPPPKEPEKT 881 AP +++ + P++ ++ P + + + P P P PP + P + Sbjct: 748 QAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRP 807 Query: 882 EEFQWPQRSQTLAQLPAEKLPPK-------KKRLRLAEMAQSSGESSFESSVPLSRSPSQ 934 + P L P + PP + +L + A + ++ P R SQ Sbjct: 808 QSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQ 867 Query: 935 ESNVSL--------SGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAR 986 L S +S + + + + AP+PS P PS PH Sbjct: 868 PPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFP--------PSQGPH-- 917 Query: 987 EMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLV 1046 +SP + H+ P P APP PP R +V Sbjct: 918 --------KSPTPPPTLHL-------------------VPEPAAPP----PPPPRTFQMV 946 Query: 1047 RQASLSRP-PESELE---VAPKGRQESEEPQPSSSKPSAKSSLSQISSAATS---HGGPP 1099 + P P++ LE P G + + + P +SL ++S A S G P Sbjct: 947 TTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAP 1006 Query: 1100 GGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLF-------SFQHLV 1152 G PT P P+A T L P LP F + Sbjct: 1007 SGT----------PTAPSHAPAPA---PMAATGL--PPLLPAENKAFASNLPTLNVAKAA 1051 Query: 1153 QHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHP 1200 PG+ P ++ S L P ++ P + F Q +VLHP Sbjct: 1052 SSGPGK-PSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHP 1098 Score = 40.4 bits (93), Expect = 0.021 Identities = 125/527 (23%), Positives = 167/527 (31%), Gaps = 158/527 (29%) Query: 1887 PHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAP 1946 P +L A S P P PA+ T V + L S+ +M + P Sbjct: 558 PVSLAAGSLPTQSQPAPAGPAATT-------VLQGVTLPPSAVAMLN-----------TP 599 Query: 1947 LGSVEKDTGSALSYK--PVSPRRPWSPSKEAGSRP-PLARKHSLTKNDSSPQRCSPAREP 2003 G V+ T +A + + PV +P + A S P PL + + A P Sbjct: 600 DGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPP 659 Query: 2004 QASAPSP-PGLHVDPGR-GMGALPCGSPRLQLSPLTL---CPLGRELAPRAHVLSKLEGT 2058 QA+ P P PGL P + +G P +P L+ +L P R P + EG Sbjct: 660 QATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLS-----AEG- 713 Query: 2059 TDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAP 2118 P L + +P A+ P + P K A GP +P + PAP Sbjct: 714 --PHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQAS-------------PAP 758 Query: 2119 LPHKLLSRSPETCASPWKAESRSPSCSPGPAH--PLSSRPFSALHDFHGHILARTEENIF 2176 P A+P K PS SP H PL P Sbjct: 759 APQI-------PAAAPLKGPG--PSSSPSLPHQAPLGDSP-------------------- 789 Query: 2177 SHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGARE 2236 HLP S H TR P P Q V +RP + P L P P Sbjct: 790 -HLP--SPHPTRPPSR--PPSRPQSV-SRPPSEPPLHPCPPPQ----------------- 826 Query: 2237 AQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTG 2296 +P F + ++L G PP + Sbjct: 827 -----------------APPTLPGIFVIQNQL----------------GVPPPASNPAPT 853 Query: 2297 APAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGC 2356 AP P P P + P P PP +P L PP SS+V Sbjct: 854 APGPPQPPLRPQSQPPEGPLPP---------APHL--------------PPSSTSSAVAS 890 Query: 2357 LAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPP 2403 +E S+R PA T + P S + P H PE PP Sbjct: 891 SSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLH-LVPEPAAPP 936 Score = 38.5 bits (88), Expect = 0.080 Identities = 63/275 (22%), Positives = 95/275 (34%), Gaps = 50/275 (18%) Query: 1049 ASLSRPPESELEVAPKGRQESEEPQPSSSKPSAK-SSLSQISSAATSHGGPPGGKGPGQD 1107 AS PP ++ + P + ++ S+ SS S SSAA+S G P ++ Sbjct: 1234 ASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRN 1293 Query: 1108 RPP-----------LGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEP 1156 RPP L + L H A P+H+ P PPP +L + + P Sbjct: 1294 RPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPP--PPPATL----KVAEPPP 1347 Query: 1157 GQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIP 1216 P T M+ + P PP+ + PL P H P+L P Sbjct: 1348 RPPPPPPPTGQMNGTVDHP------PPAAPERKPLGTAP--------HCPRL---PLRKT 1390 Query: 1217 FRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLS 1276 +R+ P T + + G LP V+ + LA + Sbjct: 1391 YRENVGGPGAPEGTPAGRARG-------GSPAPLPAKVDEATSGLIRELAAV-------- 1435 Query: 1277 PSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACP 1311 Y ++ PP P AS++ T P P P Sbjct: 1436 EDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLP 1470 Score = 37.4 bits (85), Expect = 0.18 Identities = 90/381 (23%), Positives = 129/381 (33%), Gaps = 56/381 (14%) Query: 2005 ASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCP-LGRE-LAPRAHVLSKLEGTTDPG 2062 A A + G V G G + P G+P Q PL + P LG L P +V+ L T P Sbjct: 296 AVATTLNGNSVFGGAGAASAPTGTPSGQ--PLAVAPGLGSSPLVPAPNVI--LHRTPTPI 351 Query: 2063 LPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSP----------------SAGEHGPGL 2106 P+ P P + P+ P L G P +AG+ G + Sbjct: 352 QPK--PAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNV 409 Query: 2107 GLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGH 2166 L FP L + + P T + P H L+ S++ H Sbjct: 410 VLSG---FPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQG--SSIVIPAQH 464 Query: 2167 ILARTEENIFSHLPLHS--QHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGF 2224 +L + + P Q L+ P +GG + A P L+ P ++ Sbjct: 465 MLPGQNQFLLPGAPAVQLPQQLSALPAN---VGGQILAAAAPHTGGQLIANPI---LTNQ 518 Query: 2225 SGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGP 2284 + G G A G S S+A + V + + F + L G P + + GP Sbjct: 519 NLAGPLSLGPVLAPHSGAHSAHILSAAPIQ-VGQPALFQMPVSLAAGSLPTQSQPAPAGP 577 Query: 2285 GR---------PPDW-----TPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSP- 2329 PP TP G PA P P T+ PQ A + P Sbjct: 578 AATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPL 637 Query: 2330 RLESPRA---PTNPEPSATPP 2347 L+ P+A P P P A P Sbjct: 638 GLQQPQAQQPPQAPTPQAAAP 658 Score = 36.6 bits (83), Expect = 0.31 Identities = 47/200 (23%), Positives = 72/200 (36%), Gaps = 18/200 (9%) Query: 33 SSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEA---- 88 ++ P P G A+ SP + +L P P+++L + S + Q++ + P+ A Sbjct: 661 ATTPQPSPGLAS---SPEKIVLGQPPSATPTAILTQDSLQMFLPQER--SQQPLSAEGPH 715 Query: 89 -SVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMR---PGPSGSFVAPGLHPQSQL 144 SV S + P +P P G Q D P P AP P Sbjct: 716 LSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSS 775 Query: 145 LPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKP 204 PS P D P +P P P++ +P R P +P + C P P Sbjct: 776 SPSLPHQAPLGDSPHLPS---PHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLP 832 Query: 205 SVLQKHIRSHTGERPYPCGP 224 + I++ G P P Sbjct: 833 GIFV--IQNQLGVPPPASNP 850 Score = 35.4 bits (80), Expect = 0.68 Identities = 49/199 (24%), Positives = 71/199 (35%), Gaps = 36/199 (18%) Query: 8 KGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLA-----PQPFPG- 61 KG +P + + A Q + ++ P G G +++ P Q L P P P Sbjct: 741 KGAGLGPQAPDSQASPAPAPQ--IPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTR 798 Query: 62 --------PSSVLREGSQEKTGQQQKPPKRPPIEASVHISQ----LPQHPLTPAFMSPGK 109 P SV R S+ PP+ PP + + Q +P PA +PG Sbjct: 799 PPSRPPSRPQSVSRPPSEPPL-HPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGP 857 Query: 110 PEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPS 169 P+ L + P+ P AP L P S +S LP P PS Sbjct: 858 PQPPLRPQSQPPEGPLPP-------APHLPPSSTSSAVASSSETSSRLP------APTPS 904 Query: 170 --QVSLKPTEEAHKKERKP 186 Q+ P++ HK P Sbjct: 905 DFQLQFPPSQGPHKSPTPP 923 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 73.6 bits (179), Expect = 2e-12 Identities = 176/720 (24%), Positives = 237/720 (32%), Gaps = 151/720 (20%) Query: 897 PAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGK 956 P E+LP + + + ++ G S E L+ + N SL A + Sbjct: 306 PMEELPAHSWKCKACRVCRACGAGSAE----LNPNSEWFENYSLCHRCHKAQGGQTIRSV 361 Query: 957 AEAPSP--SSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFD 1014 AE +P S P+P T P+ P A + A + P H M Sbjct: 362 AEQHTPVCSRFSPPEPGDT-----PTDEPDALYV---ACQGQPKGGHVTSMQ-------- 405 Query: 1015 YGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQP 1074 P P P+ A+ K + + L P E+ + P + P P Sbjct: 406 --------PKEPGPLQCEAKPLG----KAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPP 453 Query: 1075 SSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLH 1134 S S S++S PP P P P EAL + PL Sbjct: 454 EESPTSPPPEASRLS--------PP---------PEELPASPLPEALHL------SRPLE 490 Query: 1135 EKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQ 1194 E P PPP + + P SP S L SP S P ++PP P Sbjct: 491 ESPLSPPPE-----ESPLSPPPESSP-------FSPLEESPLSPPE------ESPPSPAL 532 Query: 1195 PTVLHPGQLHLPQLMPHPANIPFRQPPSFLPM-PYPTSSALS----SGFFLPLQSQFALQ 1249 T L P P L P P PP LP P P +S LS P + + Sbjct: 533 ETPLSPPPEASP-LSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMS 591 Query: 1250 LPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPA 1309 P + P + S + LSP E S RL P PP S P S PP P Sbjct: 592 PPPEASRLFPPFEESPLSPPPEESPLSPPPEAS---RLSP--PPEDS--PMSPPPEESPM 644 Query: 1310 CPDTMVSLVVPVRVQTNM--PSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTT 1367 P VS + P+ V + + P S + + +S + PP T Sbjct: 645 SPPPEVSRLSPLPVVSRLSPPPEESPLSPP------PEESPTSPPPEASRLSPPPEDSPT 698 Query: 1368 VCGADVHEVGPGPS----GLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSS 1423 + P P L E+S P P P P +G LS Sbjct: 699 SPPPEDSPASPPPEDSLMSLPLEESPLLPLP--EEPQLCPRSEGPHLSPRP--------- 747 Query: 1424 TAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEK 1483 + LSP E + +E S E+ PC + PE+ Sbjct: 748 ----EEPHLSPRPE-----EPHLSPQAEEPHLSPQPEE-----PCLCAV--------PEE 785 Query: 1484 SHLGNQGQG-----RRELEMLSSLSSDP--SDTKEIPPL-PHPALSHGTAPGSE--ALKE 1533 HL Q +G + E LS + +P S E P L P P SH +P SE L Sbjct: 786 PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESH-LSPQSEEPCLSP 844 Query: 1534 YPQPSGKPHRRGLTPLSVKKEDSKEQP-------DLPSLAPPSSLPLSETSSRPAKSQEG 1586 P+ S PLS + E E+P +LP PP LS PA S+ G Sbjct: 845 RPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPG 904 Score = 72.4 bits (176), Expect = 5e-12 Identities = 160/608 (26%), Positives = 209/608 (34%), Gaps = 129/608 (21%) Query: 1871 QDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCS 1930 + LS P E+P PP A R L P P D+P S +S + L S Sbjct: 668 ESPLSPPPEESPTSPPPEASR------LSPPPEDSPTSPPPEDSPASPPPEDSLM----S 717 Query: 1931 MSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKN 1990 + + P LP P + G LS +P P SP E P A + L+ Sbjct: 718 LPLEESPLLPL--PEEPQLCPRSEGPHLSPRPEEPHL--SPRPEEPHLSPQAEEPHLSPQ 773 Query: 1991 DSSPQRCSPAREPQAS--------APSPPGLHVDPGRGMGAL------PCGSPRLQLSPL 2036 P C+ EP S +P P LH+ P L PC SP+ + S L Sbjct: 774 PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHL 833 Query: 2037 TLCPLGRE--LAPR---AHVLSKLEGTTDPGLPRYSPTRRWSPGQAESP---PRSAPPGK 2088 + P E L+PR +H+ +LE P P PGQ +P P PPG+ Sbjct: 834 S--PQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEE---PGQCPAPEELPLFPPPGE 888 Query: 2089 W---------ALAGPGSPSAGEHGPGLGLDPR-------VLFPPAPLPHKL---LSRSPE 2129 AL+ PG P L L P L PP PLP L ++ + Sbjct: 889 PSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAP 948 Query: 2130 TCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRA 2189 SP E P + G + P S L I E N P+ L + Sbjct: 949 PALSPL-GELEYPFGAKGDSDPESPLAAPILET---PISPPPEANCTDPEPVPPMILPPS 1004 Query: 2190 P-CPLIPIGGIQMV----------------------QARPGAHPTLLPGPTAAWVSGFSG 2226 P P+ P I M Q P A P +P P + G Sbjct: 1005 PGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSP--IGKVV 1062 Query: 2227 GGSDLTGARE------------AQERGRWSPTES-----SSASVSPVAKVSKFTLSSE-- 2267 G SD E A E SP S S + SP + F+ E Sbjct: 1063 GVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDT 1122 Query: 2268 --LEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTH-SPCTPPDTLPRPPQGRRAA 2324 L+G D P + G PG G+P P +P TP + P + ++ A Sbjct: 1123 APLDGIDAPGSQPEPGQTPG---SLASELKGSPVLLDPEELAPVTPMEVYP---ECKQTA 1176 Query: 2325 QSWSP--RLESPRAPTNPEPSATPPLDRSSSVGCLA--EASARFPARTRNLSGEPRTRQD 2380 SP E PRAP P P D + + L+ +ASA FP EP Sbjct: 1177 GQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFP------GSEPLL--G 1228 Query: 2381 SPKPSGSG 2388 SP P G G Sbjct: 1229 SPDPEGGG 1236 Score = 62.8 bits (151), Expect = 4e-09 Identities = 169/733 (23%), Positives = 245/733 (33%), Gaps = 140/733 (19%) Query: 1755 VCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQETG 1814 VC CG + + + ++ +C CH K +G T ++ H+ C Sbjct: 322 VCRACGAGSAELNPNSEWFENYS-----LCHRCH---KAQGGQTIRSVAEQHTPVCSRFS 373 Query: 1815 VLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLE----------------DSDSDSD 1858 E + D L+ +G+ V Q + + ++ Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAP 433 Query: 1859 LDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGT-EATRGSS 1917 L+E+ + LS P E+P PP A R L P P + PAS EA S Sbjct: 434 LNEEMPLLPPPEESPLSPPPEESPTSPPPEASR------LSPPPEELPASPLPEALHLSR 487 Query: 1918 VSEAERLTA----SSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSK 1973 E L+ S S +S P P L +PL E+ S P+SP SP Sbjct: 488 PLEESPLSPPPEESPLSPPPESSPFSP-LEESPLSPPEESPPSPALETPLSPPPEASPLS 546 Query: 1974 EAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRL-- 2031 PL+ P+ + P+ S SPP P + P + RL Sbjct: 547 PPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP-----PEESPMSPPPEASRLFP 601 Query: 2032 --QLSPLTLCPLGRELAPRAHVLSKLEGTTD----------------PGLPRYSP---TR 2070 + SPL+ P L+P S+L + P + R SP Sbjct: 602 PFEESPLSPPPEESPLSPPPEA-SRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS 660 Query: 2071 RWSPGQAESP--------PRSAPPGKWALAGP-----------GSPSAGEHGPGLGLDPR 2111 R SP ESP P S PP L+ P SP++ L P Sbjct: 661 RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720 Query: 2112 VLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHP-LSSR---PFSALHDFHGHI 2167 P PLP + P+ C S P SP P P LS R P + H+ Sbjct: 721 EESPLLPLPEE-----PQLC-----PRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHL 770 Query: 2168 LARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGG 2227 + EE +P +A P + ++ + P L P P +S Sbjct: 771 SPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLS----- 825 Query: 2228 GSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGR- 2286 E SP +S +SP + S LS ELE E+ PG+ Sbjct: 826 --------PQPEESHLSP-QSEEPCLSPRPEESH--LSPELEKPPLSPRPEKPPEEPGQC 874 Query: 2287 ---------PPDWTPHGT---GAPAEPTPTHSPCTP-PDTLPRPPQGRRAAQSWSPRLES 2333 PP P + G PA P P +P P+ LP P G P L Sbjct: 875 PAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG-------EPSLSP 927 Query: 2334 PRAPTNPEPSATPPLDRSSSVGCLAE-ASARFPARTRNLSGEPRTRQDSP--KPSGSGEP 2390 P +P P P+ +++ L+ +P + +P + +P + S P Sbjct: 928 QLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKG-DSDPESPLAAPILETPISPPP 986 Query: 2391 RAHPHQPEDRVPP 2403 A+ PE VPP Sbjct: 987 EANCTDPEP-VPP 998 Score = 61.2 bits (147), Expect = 1e-08 Identities = 209/918 (22%), Positives = 304/918 (33%), Gaps = 146/918 (15%) Query: 674 PISAGTHTSP-----EAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDE-EEP 727 P+S +SP E+ S E P S + L E +PL +E L EE Sbjct: 502 PLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL 561 Query: 728 PAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESG 787 P ++ SP P ++ + P E +SP P L P P +P P ES Sbjct: 562 PTSPPPEASRLSPPPEESPMSPPPE--ESPMSPPPEASRLFPPFEESPLSPPP---EESP 616 Query: 788 KERRTTSKEISVIQHTSSF----EKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSL 843 + +S S E+S P P+ SPPP L Sbjct: 617 LSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPP-----EESPL 671 Query: 844 QPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLP- 902 P P PE P P+ P PP E P +L LP E+ P Sbjct: 672 SPPPEESPTSPPPEASRLSPP--PEDSPTSPPPEDSPAS----PPPEDSLMSLPLEESPL 725 Query: 903 -PKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAP- 960 P + +L ++ S LS P +E ++S S + ++ P Sbjct: 726 LPLPEEPQLCPRSEGPHLSPRPEEPHLSPRP-EEPHLSPQAEEPHLSPQPEEPCLCAVPE 784 Query: 961 ----SPSSD---MRPKPLGTHMLTVPSHHPHAREM-RRSASEQSPNVSHSAHMTETRSKS 1012 SP ++ + P+P H L+ + PH + P SH + +E S Sbjct: 785 EPHLSPQAEGPHLSPQPEELH-LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLS 843 Query: 1013 FDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPK-GRQESEE 1071 L+ P++P P E +C + L PP E ++P G E Sbjct: 844 PRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLF-PPPGEPSLSPLLGEPALSE 902 Query: 1072 P-QPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTV-----PYTEALQVFH 1125 P +P S + LS + S P P PPL P + P L Sbjct: 903 PGEPPLSPLPEELPLSPSGEPSLS----PQLMPPDPLPPPLSPIITAAAPPALSPLGELE 958 Query: 1126 HPVAQ-----------TPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLL-- 1172 +P P+ E P PPP + + +P P + S + Sbjct: 959 YPFGAKGDSDPESPLAAPILETPISPPPEANCT-------DPEPVPPMILPPSPGSPVGP 1011 Query: 1173 SSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPP----------- 1221 +SP M PLPP L P P Q P L P ++P P Sbjct: 1012 ASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPAL---PLSVPSPLSPIGKVVGVSDEA 1068 Query: 1222 -----SFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLS 1276 + P AL PL S GD+ P S AP +GL Sbjct: 1069 ELHEMETEKVSEPECPALEPSATSPLPSPM-----GDLSCPAP----SPAPALDDFSGLG 1119 Query: 1277 PSTEYSSDIRLP-----PVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYG 1331 T I P P P S ++ P+ L P+ + V P+ V Sbjct: 1120 EDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLD--PEELAP-VTPMEV-------- 1168 Query: 1332 SAMYTTLSQILVTQSQGSSA-TVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSE-EQSR 1389 Y Q T QGS P+ P+ T + V+E+ S LS+ + S Sbjct: 1169 ---YPECKQ---TAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEI----SNLSQGDASA 1218 Query: 1390 AFP--TPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPA-----GSLELTM 1442 +FP P L P G SLS E +S + S + GS R+ + + SL Sbjct: 1219 SFPGSEPLLGSP---DPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDA 1275 Query: 1443 ETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELE----- 1497 T E E + + +S +RP G +G+GR L+ Sbjct: 1276 GTAISGGKAEGEKGRRRSSPARSRIKQGRSSSFPGRRRPRGGAHGGRGRGRARLKSTASS 1335 Query: 1498 ----MLSSLSSDPSDTKE 1511 +++ + S PS +E Sbjct: 1336 IETLVVADIDSSPSKEEE 1353 Score = 60.1 bits (144), Expect = 3e-08 Identities = 221/1024 (21%), Positives = 329/1024 (32%), Gaps = 162/1024 (15%) Query: 184 RKPQKPGKY-ICQYCSRP----CAKPSVLQKHIRSHTGERPYPCGPCGFSFK--TKSNLY 236 RKP K +C+ C + C KP + + S + C CG ++ + Sbjct: 280 RKPGNDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEW 339 Query: 237 KHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEET-------S 289 S HR GG+ E F P G++ E + Sbjct: 340 FENYSLCHRCH----KAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQ 395 Query: 290 ATSGHPAELSPRPKQPLLSSG--LYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSE 347 GH + P+ PL L +G L++ P + P E Sbjct: 396 PKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEM---------PLLPPPEE 446 Query: 348 HPLSHKPEDTHTIKQKLALRLSERKKVID--------------EQAFLSPGSKGS----- 388 PLS PE++ T A RLS + + E++ LSP + S Sbjct: 447 SPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPP 506 Query: 389 TESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDK 448 ES FS E E +SPP + S A T + PL P E Sbjct: 507 PESSPFSPLE--ESPLSPPEESPPSPA-----------LETPLSPPPEASPLSPPFEESP 553 Query: 449 PSLVPLSVPRTQVIEHITKLITINEAVVD--TSEIDSVKPRRSSLSRRSSMESPKSSLYR 506 S P +P + E E+ + E P +S ESP S Sbjct: 554 LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE 613 Query: 507 E-PLSSHSEKTK-------------PEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTI-- 550 E PLS E ++ PE+S +S S P+P++ S P + Sbjct: 614 ESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP 673 Query: 551 -------STPHHPFRGSYSFDDHIT-----DSEALSHSSHVFTSHPRMLKRQPAIELPLG 598 S P R S +D T DS A S P L+ P + LP Sbjct: 674 PPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLP--LEESPLLPLPEE 731 Query: 599 GEYSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNY 658 + GP +P P+E L+ + ++ + C +C + + Sbjct: 732 PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPC-LCAVPEEPHLSP 790 Query: 659 EA---HKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKR 715 +A H EL ++ P + H SP E+ + +P L E L R Sbjct: 791 QAEGPHLSPQPEELHLS-PQTEEPHLSPVPEEPCLSPQPEES----HLSPQSEEPCLSPR 845 Query: 716 RKEKSLGDE-EEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQ 774 +E L E E+PP + PG A LPL P EPS S P L P Sbjct: 846 PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPL--FPPPGEPSLS-PLLGEP---- 898 Query: 775 PRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPA 834 + SE G+ + E + + S L P L P+ +PP Sbjct: 899 -------ALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL 951 Query: 835 --------PHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQW 886 P G S + P ++ P I E + D EP PP P Sbjct: 952 SPLGELEYPFGAKGDSDPESPLAAPILETP-ISPPPEANCTDPEPVPPMILPPSPGSPVG 1010 Query: 887 PQRSQTLAQLPAEKLPPKKKRLRLAEMAQSS-GESSFESSVPLSRSPSQESNVSLSGSSR 945 P + LP + P + L S + SVP SP + V +S + Sbjct: 1011 PASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKV-VGVSDEAE 1069 Query: 946 SASFERDDHGKAEAPS---PSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHS 1002 E + + E P+ ++ P P+G PS P + + +P Sbjct: 1070 LHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAP----- 1124 Query: 1003 AHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVA 1062 + G S P P P +A + L+ L+ P + +EV Sbjct: 1125 ------------LDGIDAPG-SQPEPGQTPGSLASELKGSPVLLDPEELA--PVTPMEVY 1169 Query: 1063 PKGRQ---------ESEEPQ-PSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLG 1112 P+ +Q E EEP+ P + P ++ + G PG + P LG Sbjct: 1170 PECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSE-PLLG 1228 Query: 1113 PTVP 1116 P Sbjct: 1229 SPDP 1232 Score = 52.8 bits (125), Expect = 4e-06 Identities = 124/544 (22%), Positives = 189/544 (34%), Gaps = 97/544 (17%) Query: 812 LEQPSG-LEGEDKPLAQFPSPPPA---------PHGRS-AHSLQPKLVRQPNIQVPEILV 860 L+ P+G + G D P F PP P G + A+ L+P+ P P Sbjct: 2143 LKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSP 2202 Query: 861 TEEPDRPDTEPEPPPKEPEKTEEFQW--PQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSG 918 T P +P + EF P + P L P+ L + +S G Sbjct: 2203 TGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG 2262 Query: 919 ESSFESSVPL-SRSPSQESNVSLS------GSSRSASFERDDHGKAEAPSPSSDMRPKPL 971 ++S PL S P ES +L G+S S S+ + G ++PS + + L Sbjct: 2263 VGGGKASEPLLSPPPFGESRKALEVKKEELGAS-SPSYGPPNLGFVDSPSSGTHLGGLEL 2321 Query: 972 GTHMLTVPSHHPHAREMRRSAS------EQSPNVSHSAHMTETRSKSFDYGSLSLTGPSA 1025 T + P A ++ + ++ P A + F GS T P A Sbjct: 2322 KTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSY--TDPYA 2379 Query: 1026 PAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEE---PQPSSSKPSAK 1082 P+ P + PPE C + SL P S + +P+ + S+ P+P S++ Sbjct: 2380 QPPLTPRPQPPPPE--SCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCP 2437 Query: 1083 SSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPP 1142 S ++ + + PP Q R P PLH+ P PP Sbjct: 2438 SPVTPRFQSPDPYSRPPSRP---QSRDPF-------------------APLHKPPRPQPP 2475 Query: 1143 VSLFSFQHLVQHE-----------------------PGQSPEFFSTQAMSSLLSSPYSMP 1179 F L GQ P F + + + +P M Sbjct: 2476 EVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMR 2535 Query: 1180 PLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFF 1239 P P L+P V PG LP PH N F P+ L P T+ +++G F Sbjct: 2536 FTFPQAVGEP--SLKPPVPQPG---LPP--PHGINSHFGPGPT-LGKPQSTNYTVATGNF 2587 Query: 1240 LPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAP 1299 P S ES+ L+PL S P+ + S LP ++ AS + Sbjct: 2588 HPSGSPLGPSSGSTGESY------GLSPLRPPSVLPPPAPDGS----LPYLSHGASQRSG 2637 Query: 1300 TSAP 1303 ++P Sbjct: 2638 ITSP 2641 Score = 47.0 bits (110), Expect = 2e-04 Identities = 266/1251 (21%), Positives = 380/1251 (30%), Gaps = 260/1251 (20%) Query: 1022 GPSAPAPVAPPARVAPP--ERRKCFLVRQASLSR------PPESELEVAPKGRQES---E 1070 G A P+ P PP E RK V++ L PP +P E Sbjct: 2265 GGKASEPLLSP----PPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLE 2320 Query: 1071 EPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQ 1130 P K SQ+ + G P P Q P P+ P + P AQ Sbjct: 2321 LKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQ 2380 Query: 1131 TPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAP- 1189 PL +P PPP S + P P ++ +S S S PL P A Sbjct: 2381 PPLTPRPQPPPPESCCAL------PPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEA 2434 Query: 1190 --PLPLQPTVLHPGQLHLPQLMPHPAN--IPFRQPPSFLPMPYPTSSALSSGFFLPLQ-- 1243 P P+ P P P P + P +P P P P A +G Sbjct: 2435 FCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKP----PRPQPPEVAFKAGSLAHTSLG 2490 Query: 1244 -SQFALQLPGDVESHL-PQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTS 1301 F LP L ++ + P S G S +R P + P+ Sbjct: 2491 AGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRF---TFPQAVGEPSL 2547 Query: 1302 APPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEP 1361 PP+ P P P +G + L + Q ++ TVA F Sbjct: 2548 KPPVPQPGLP----------------PPHGINSHFGPGPTL-GKPQSTNYTVATGNFHPS 2590 Query: 1362 -----PSKGTTVCGADVHEVGP-GPSGLSEEQSRAFPTPYL------RVPVTLPERK--- 1406 PS G+T + + + P P + + PYL R +T P K Sbjct: 2591 GSPLGPSSGST---GESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKRED 2647 Query: 1407 -GTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQK------RVKEEEASKAD 1459 GT + S ++ G +S EL + Q+Q+ R + + + Sbjct: 2648 PGTGMGSSL-----ATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQ 2702 Query: 1460 EKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPP--LPH 1517 EK V G P +G+ + + D S +PP L Sbjct: 2703 EKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPF----AGTQDKSSLVGLPPSKLSG 2758 Query: 1518 PALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSK----EQPDLPSLAPPSSLPL 1573 P L G+ P + L P P+ TP S+ + Q P SLPL Sbjct: 2759 PILGPGSFPSDDRLSRPPPPA--------TPSSMDVNSRQLVGGSQAFYQRAPYPGSLPL 2810 Query: 1574 SETSSRPAKSQEGTDSKKV-----LQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYA 1628 + + + Q+ T + + +FPS P S A Sbjct: 2811 QQQQQQLWQQQQATAATSMRFAMSARFPS---------------TPGPELGRQALGSPLA 2855 Query: 1629 GWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEV 1688 G L P P + + V K T P P G ++PR V Sbjct: 2856 GISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGT-PFPGQG-----PPQRPRFYPV 2909 Query: 1689 -HLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGE-------------PARIKIFE 1734 P ++PEG + LA ++ P PA + P +++ Sbjct: 2910 SEDPHRLAPEGLRGLAVSGLPPQKPSAP----PAPELNNSLHPTPHTKGPTLPTGLELVN 2965 Query: 1735 GGYKSNEEYVYVRGRGRGKYVCEECG-IRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKT 1793 S E GR + E G + C+ P + H A + Sbjct: 2966 RPPSSTE-------LGRPNPLALEAGKLPCEDPELDDDF-------------DAHKALED 3005 Query: 1794 KGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDS 1853 L +K E G LE LE + DDL E + E D +D Sbjct: 3006 DEELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDI 3065 Query: 1854 DSDSDLDEDEDEDEEESQDELSR---PSSEAPPPGPPHALRADS---------------- 1894 ++ L E +E+ ++ L R P P PP A A Sbjct: 3066 FNE-HLRLVESANEKAEREALLRGVEPGPLGPEERPPPAADASEPRLASVLPEVKPKVEE 3124 Query: 1895 -----SP----ILGPQPPDAPAS--------------GTEATR-GSSVSEAERLTASSCS 1930 SP I P+ APA+ G+ TR G+ + TA S Sbjct: 3125 GGRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKAS 3184 Query: 1931 MSSQSMPGLPWLGPAPL----GSVEKDTGSALSYKPVSPRRPWSPSKE--------AGSR 1978 + P L P+PL GS + S P P + E S Sbjct: 3185 FGATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASE 3244 Query: 1979 PPLA-------RKHSLTKNDSSPQRCSPAREPQ--------ASAPSPPGLHVDPGRGMGA 2023 PL K L K + PA++ Q SAP P P G Sbjct: 3245 LPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSP 3304 Query: 2024 LPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRS 2083 GS + QLS LG L G PGLP+ P P A + + Sbjct: 3305 SLAGSQQ-QLS------LG------------LAGARQPGLPQ--PLMPTQP-PAHALQQR 3342 Query: 2084 APPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASP 2134 P ++ G +G+HG GL P+ P + + P C P Sbjct: 3343 LAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKP 3393 Score = 44.3 bits (103), Expect = 0.001 Identities = 46/161 (28%), Positives = 62/161 (38%), Gaps = 28/161 (17%) Query: 38 PGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEA-------SV 90 P + T P L+P P P+S L E ++ P PP E+ S Sbjct: 451 PPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESS 510 Query: 91 HISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHAS 150 S L + PL+P SP P L P+ P P S ++P +S L P Sbjct: 511 PFSPLEESPLSPPEESPPSP---------ALETPLSPPPEASPLSPPFE-ESPLSP---- 556 Query: 151 IIPPEDLPGVPKVFVPRPSQVSLKPTEE--AHKKERKPQKP 189 PPE+LP P P S++S P E + E P P Sbjct: 557 --PPEELPTSPP---PEASRLSPPPEESPMSPPPEESPMSP 592 Score = 43.5 bits (101), Expect = 0.003 Identities = 69/313 (22%), Positives = 101/313 (32%), Gaps = 58/313 (18%) Query: 46 QESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFM 105 +ESP P P R + PP+ P+ +S+L P+ Sbjct: 604 EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLS 663 Query: 106 SPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLH--PQSQLLPSHASIIPPED----LPG 159 P + L S P P P S ++P P S + PPED LP Sbjct: 664 PPPEESPL---SPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720 Query: 160 VPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERP 219 +P P + L P E +P++P ++ P P + H+ P Sbjct: 721 EESPLLPLPEEPQLCPRSEGPHLSPRPEEP--HLSPRPEEPHLSPQAEEPHL------SP 772 Query: 220 YPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEG 279 P PC + + +L + G + P E+ P + EEP Sbjct: 773 QPEEPCLCAVPEEPHLSPQAE--------------GPHLSPQPEELHLSP--QTEEP--- 813 Query: 280 ESTDSEEETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERC---SLSQSSTAQSLE 336 LSP P++P LS S S E C +S + LE Sbjct: 814 -----------------HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELE 856 Query: 337 DPPPFVEPSSEHP 349 PP + P E P Sbjct: 857 KPP--LSPRPEKP 867 Score = 40.8 bits (94), Expect = 0.016 Identities = 66/262 (25%), Positives = 86/262 (32%), Gaps = 70/262 (26%) Query: 1867 EEESQDELSRPSSEAPPPGPPHALRADSSP----ILGPQP-----PDAPASGTEATRGSS 1917 + + + L+ P E P PP A D P IL P P P +P S Sbjct: 966 DSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCS 1025 Query: 1918 VSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGS 1977 L + S S P LP P+PL + K G VS Sbjct: 1026 PLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVG-------VSDE----------- 1067 Query: 1978 RPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLT 2037 A H + S C PA EP A++P P MG L C +P + Sbjct: 1068 ----AELHEMETEKVSEPEC-PALEPSATSPLP--------SPMGDLSCPAPSPAPALDD 1114 Query: 2038 LCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSP 2097 LG + AP L+G PG + PGQ PGS Sbjct: 1115 FSGLGEDTAP-------LDGIDAPG-------SQPEPGQT----------------PGSL 1144 Query: 2098 SAGEHGPGLGLDPRVLFPPAPL 2119 ++ G + LDP L P P+ Sbjct: 1145 ASELKGSPVLLDPEELAPVTPM 1166 Score = 38.5 bits (88), Expect = 0.080 Identities = 110/443 (24%), Positives = 150/443 (33%), Gaps = 96/443 (21%) Query: 1976 GSRPPLARKHSLTKNDSSPQRCSPARE-----PQASAPSPPGLHVDPGRGMGALPCGSPR 2030 GS PP A + ++P S + + P S P P PG LP P+ Sbjct: 2114 GSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDS----PGELFLKLP---PQ 2166 Query: 2031 LQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQ-----AESPPRSAP 2085 + + P G LAP A+ L T P P Y P+ +P Q A S P + Sbjct: 2167 VPAQVPSQDPFG--LAP-AYPLEPRFPTAPPTYPPY-PSPTGAPAQPPMLGASSRPGAGQ 2222 Query: 2086 PGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCS 2145 PG++ PG+P H P DP L P P S + A P SP Sbjct: 2223 PGEFHTTPPGTP---RHQPSTP-DP-FLKPRCP--------SLDNLAVP-----ESPGVG 2264 Query: 2146 PGPAHP--LSSRPFSALHDFHGHILARTEENIFSHLPLHSQH---LTRAPCPLIPIGGIQ 2200 G A LS PF L +E + + P + +P +GG++ Sbjct: 2265 GGKASEPLLSPPPFGESRK----ALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLE 2320 Query: 2201 MVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVS 2260 + P P A+ V S G G R + P + + + SP + Sbjct: 2321 LKTPDVFKAPLT---PRASQVEPQSPG----LGLRPQE------PPPAQALAPSPPSHPD 2367 Query: 2261 KFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQG 2320 F S + P P TP P P P PP +LP P Sbjct: 2368 IFRPGSYTD--------------PYAQPPLTPR----PQPPPPESCCALPPRSLPSDPFS 2409 Query: 2321 RRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQD 2380 R A S S ++P P P + AEA P R S +P +R Sbjct: 2410 RVPASPQSQ--SSSQSPLTPRPLS-------------AEAFCPSPVTPRFQSPDPYSR-- 2452 Query: 2381 SPKPSGSGEPRAHPHQPEDRVPP 2403 P S +P A H+P PP Sbjct: 2453 PPSRPQSRDPFAPLHKPPRPQPP 2475 Score = 37.7 bits (86), Expect = 0.14 Identities = 57/271 (21%), Positives = 99/271 (36%), Gaps = 35/271 (12%) Query: 840 AHSLQPKLVRQP-----NIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLA 894 +HS QPKL QP +Q + L ++ + + + ++ + ++ Q Q+ Q L Sbjct: 3882 SHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQ 3941 Query: 895 QLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDH 954 Q ++L ++++L + Q + F+ Q+ + L SR+ + Sbjct: 3942 QQQQQQLQQQQQQL---QQQQQQQQQQFQQQ-------QQQQQMGLLNQSRTLLSPQQQQ 3991 Query: 955 GKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFD 1014 + A P M KPL H + + P + + P VS A T S Sbjct: 3992 QQQVALGPG--MPAKPL-QHFSSPGALGPTLLLTGKEQNTVDPAVSSEA----TEGPSTH 4044 Query: 1015 YGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQP 1074 G G + + P V P L+ +P S L++ P R ++ Q Sbjct: 4045 QGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQ- 4103 Query: 1075 SSSKPSAKSSLSQISSAATSHGGPPGGKGPG 1105 Q+S T+ GG G G G Sbjct: 4104 ------------QVSLLHTAGGGSHGQLGSG 4122 Score = 36.2 bits (82), Expect = 0.40 Identities = 69/273 (25%), Positives = 97/273 (35%), Gaps = 49/273 (17%) Query: 1856 DSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPP------------ 1903 +++L E E E E + PS+ +P P P L S P P P Sbjct: 1067 EAELHEMETEKVSEPECPALEPSATSPLPSPMGDL---SCPAPSPAPALDDFSGLGEDTA 1123 Query: 1904 -----DAPASGTE--ATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGS 1956 DAP S E T GS SE L S + + + + + P GS Sbjct: 1124 PLDGIDAPGSQPEPGQTPGSLASE---LKGSPVLLDPEELAPVTPMEVYPECKQTAGQGS 1180 Query: 1957 ALSYKPVSPRRPWSPSKEAGSRPPLARKHS-LTKNDSSPQRCSPAREPQASAPSPPG--- 2012 + PR P +P+ + + + S L++ D+S P EP +P P G Sbjct: 1181 PCE-EQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASAS--FPGSEPLLGSPDPEGGGS 1237 Query: 2013 --------LHVDPGRGMGALP-CGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGL 2063 V P R G+L C + LC G ++ K EG + G Sbjct: 1238 LSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISG-----GKAEG--EKGR 1290 Query: 2064 PRYSPTR-RWSPGQAESPPRSAPPGKWALAGPG 2095 R SP R R G++ S P P A G G Sbjct: 1291 RRSSPARSRIKQGRSSSFPGRRRPRGGAHGGRG 1323 Score = 35.4 bits (80), Expect = 0.68 Identities = 28/95 (29%), Positives = 35/95 (36%), Gaps = 15/95 (15%) Query: 1021 TGP-----SAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPS 1075 TGP + P P PP APP V PP S +EP+ Sbjct: 4271 TGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSS----------PQEPKRP 4320 Query: 1076 SSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPP 1110 S PS S L + +H G P +GP + PP Sbjct: 4321 SQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPP 4355 Score = 34.7 bits (78), Expect = 1.2 Identities = 21/67 (31%), Positives = 26/67 (38%), Gaps = 1/67 (1%) Query: 2287 PPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATP 2346 PP P +P P+P P P LP P S P SP + P+P A P Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPES-ARPKPRARP 4967 Query: 2347 PLDRSSS 2353 P + S Sbjct: 4968 PEEGEDS 4974 Score = 34.3 bits (77), Expect = 1.5 Identities = 29/112 (25%), Positives = 47/112 (41%), Gaps = 8/112 (7%) Query: 795 KEISVIQHTSSFEKSDSLEQP-SGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNI 853 ++ ++ T +++ + P GL G L FP P P +P+ P + Sbjct: 4232 QQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQ--GPPRL 4289 Query: 854 QVPEILVTEEPDRPDTEPEPPPKEPEKTEE-FQWPQRSQTLAQLPAE-KLPP 903 P ++ P P PPP P++ + Q P S +QLP E +LPP Sbjct: 4290 PAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPS---SQLPTEAQLPP 4338 Score = 33.5 bits (75), Expect = 2.6 Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 14/96 (14%) Query: 1500 SSLSSDPSDTKEIPPLPHPALS----HGTAPGSEALKEYPQ--PSGKPHRRGLTPLSVKK 1553 ++LS+ P+ +PP P P++ +G P SE L E+P+ S + R L Sbjct: 4614 NNLSNPPTPPSSLPPTPPPSVQQKMVNGVTP-SEELGEHPKDAASARDSERAL------- 4665 Query: 1554 EDSKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDS 1589 D+ E L LA + P ++T +S E +DS Sbjct: 4666 RDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDS 4701 >gi|154146199 sal-like 3 [Homo sapiens] Length = 1300 Score = 72.8 bits (177), Expect = 4e-12 Identities = 108/423 (25%), Positives = 156/423 (36%), Gaps = 78/423 (18%) Query: 3 PEQSVKGTKKAEGSPRKRLTKGEAIQTSVSS-SVPYPGSGTAATQE-SPAQELLAPQPFP 60 P S A G +L A+ S + + GSG AA AQ L P+ Sbjct: 240 PSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGA 299 Query: 61 GPSSVLREGSQEKTGQQQKPPKRP---PIEASVHISQLPQHPLTPAFMSPGKPEHLLEGS 117 E S P P P S SQ PQ TP ++PG L G+ Sbjct: 300 STPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQ-PQSASTPPALAPGS----LLGA 354 Query: 118 TWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTE 177 L P+ P S S G+ + L+ A+ + L + K +P VS+ Sbjct: 355 APGLPSPLLPQTSAS----GVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSV---- 406 Query: 178 EAHKKERKPQKPG-KYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLY 236 + + + P K+ C++C++ S LQ H+RSHTGERP+ C CG F TK NL Sbjct: 407 --FEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLK 464 Query: 237 KHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPA 296 H + H E YPH ++M P E+ + SG P Sbjct: 465 VHFQRHK-------------EKYPH-IQMNPYPVPEY-----------LDNVPTCSGIPY 499 Query: 297 ELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPP------FVEPSSEHPL 350 +S P++P+ + + L T+ L+ PP + + S P Sbjct: 500 GMSLPPEKPVT----------TWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPA 549 Query: 351 SHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQV-SPPNT 409 S P+ E A LSPG ESG + +ES + + PP T Sbjct: 550 SRSPQ--------------RPSPASSECASLSPG-LNHVESGVSATAESPQSLLGGPPLT 594 Query: 410 NAK 412 A+ Sbjct: 595 KAE 597 Score = 61.6 bits (148), Expect = 9e-09 Identities = 171/785 (21%), Positives = 275/785 (35%), Gaps = 124/785 (15%) Query: 1288 PPVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQ 1347 P ++P A+ SAP AP LP +S P A + + ++ + Sbjct: 240 PSLSPAAAPSAPGPAPS-QLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPL--SRPE 296 Query: 1348 GSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKG 1407 ++T P P+ + P P + Q ++ TP P +L G Sbjct: 297 SGASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSL---LG 353 Query: 1408 TSLSSESILSLEGSSSTAGGSKRVLS---PAGSLELTMETQQQKRVKEEEASKADEKLEL 1464 + S L + S+S ++S A +L+ + ++ K S + K Sbjct: 354 AAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASA 413 Query: 1465 VKP--------CSVVLTS---------TEDGKRPEKSHL-GNQGQGRRELEMLSSLSSDP 1506 P C+ V S + G+RP K ++ GN+ + L++ + Sbjct: 414 EDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK 473 Query: 1507 SDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLA 1566 ++ P P P E L P SG P+ L P +P LP++ Sbjct: 474 YPHIQMNPYPVP----------EYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVP 523 Query: 1567 PPSSLPLSET---SSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCY-LNYIKPNHIQHADR 1622 L L T + A S T + + Q PS ++ S LN+++ A+ Sbjct: 524 TSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAES 583 Query: 1623 RSSVYAGWCISLYNP-NLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSR 1681 S+ G ++ P +LP + +A + + ++ + + A G S Sbjct: 584 PQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQF 643 Query: 1682 KPRMTEVHL-PSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSN 1740 K + L S+ + E K VE +++ +P + Sbjct: 644 KAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQ----------------------- 680 Query: 1741 EEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800 C C S LK H RTHT RP+ CK C AF TKGNL H Sbjct: 681 ---------------CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTH 725 Query: 1801 M---KSK-----AHS-----KKCQETGVLEE-LEAEEGTSDDLFQDSEGREGSEAVEEHQ 1846 ++K HS KK VL++ + G EG + +A++ Sbjct: 726 FGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQ--DAMDSEL 783 Query: 1847 FSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAP 1906 D +++++ S D+D DE+ E EL A P P A S P P PP Sbjct: 784 AYDDKNAETLSSYDDDMDENSMEDDAEL---KDAATDPAKPLLSYAGSCP---PSPPSVI 837 Query: 1907 ASGTEATRGSSVSEAE-RLTASSCSMSSQSMPGLPWL--GPAPLGSVEKDTGSAL----S 1959 SS++ E ++ MS Q + GL + G + D+ SA+ S Sbjct: 838 ---------SSIAALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLES 888 Query: 1960 YKPVSPRRPWSPSKEAGSRPPLARKHSLTKN-----DSSPQRCSPAREPQASAPSPPGLH 2014 SP S S +A S P + +K+ PQ E S + PG Sbjct: 889 RSAGSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSG 948 Query: 2015 VDPGR 2019 PGR Sbjct: 949 GAPGR 953 Score = 56.6 bits (135), Expect = 3e-07 Identities = 49/159 (30%), Positives = 67/159 (42%), Gaps = 20/159 (12%) Query: 92 ISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDP-MRPGPSGSF------VAPGLHPQSQL 144 + L QH LT H L+ QL DP GPS S AP + Sbjct: 1017 MGNLKQHLLT----------HRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKME-- 1064 Query: 145 LPSHASIIPPEDLPGVPK-VFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAK 203 + H + + P +P V VP Q + P + P ++ CQ C + + Sbjct: 1065 VNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSS 1124 Query: 204 PSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242 S LQ H R+HTGE+P+ C CG +F TK NL H +H Sbjct: 1125 ASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 Score = 56.2 bits (134), Expect = 4e-07 Identities = 167/708 (23%), Positives = 240/708 (33%), Gaps = 129/708 (18%) Query: 753 STKSPAEPS--KSVPSLEGPTGFQPRTPKPGSGSE---SGKERRTTSKEISVIQHTSS-- 805 S + A+P KS L P G P PG G+E SG E R+ +E SV + + Sbjct: 2 SRRKQAKPQHLKSDEELLPPDG-APEHAAPGEGAEDADSGPESRSGGEETSVCEKCCAEF 60 Query: 806 FEKSDSLEQ--------PSGLEGEDKPLA---QFPSPPPAPH-GRSAHSLQPKLVRQPNI 853 F+ +D LE P + ED P FP P PA A S + Sbjct: 61 FKWADFLEHQRSCTKLPPVLIVHEDAPAPPPEDFPEPSPASSPSERAESEAAEEAGAEGA 120 Query: 854 QVPEILVTEEPDRPDTEP-------EPPPKEPEK-TEEFQWPQRSQTLAQLPAEKLPPKK 905 + V +E + D EP PPP P T + P + TL L L K Sbjct: 121 EGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTPAYGAPSTNVTLEAL----LSTKV 176 Query: 906 KRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFE-----RDDHGKAEAP 960 + ++ A+++G S V + P + + + R + P Sbjct: 177 AVAQFSQGARAAGGSGAGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRP 236 Query: 961 SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSL 1020 P + P + PS P + SA + ++ S Sbjct: 237 PPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGS------------------ 278 Query: 1021 TGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS 1080 GP+APA ++ PE ++ P E AP P P+ + S Sbjct: 279 -GPAAPAAFEGAQPLSRPESGA------STPGGPAEPSAPAAPSAAPAPAAPAPAPAPQS 331 Query: 1081 AKSSLSQISSAATSHGGPPG---GKGPGQDRPPLGPTVPYTEALQV-FHHPV-------- 1128 A S SQ SA+T PG G PG P +P T A V F +P+ Sbjct: 332 AAS--SQPQSASTPPALAPGSLLGAAPGLP----SPLLPQTSASGVIFPNPLVSIAATAN 385 Query: 1129 AQTPL-----HEKPYLPPPVSLFS---------FQHLVQHEPGQSPEFFSTQAMSSLLSS 1174 A PL H K PP VS+F F+H + + F S A+ L S Sbjct: 386 ALDPLSALMKHRKG-KPPNVSVFEPKASAEDPFFKHKCRF---CAKVFGSDSALQIHLRS 441 Query: 1175 PYSMPPLPPSL----FQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPT 1230 P ++ F H + Q+ P+P P +L PT Sbjct: 442 HTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPV-------PEYLD-NVPT 493 Query: 1231 SSALSSGFFLPLQSQFALQLPGDVESHLPQIKTS----LAPLATGSAGLSPSTEYSSDIR 1286 S + G LP + L D + LP + TS L P G+ G + S + R Sbjct: 494 CSGIPYGMSLPPEKPVTTWL--DSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASR 551 Query: 1287 LPPVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILV--T 1344 P PASS + +P L V V ++ G T + + T Sbjct: 552 SPQRPSPASSECASLSPGL-------NHVESGVSATAESPQSLLGGPPLTKAEPVSLPCT 604 Query: 1345 QSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFP 1392 ++ A V P T+V GA PG +SE+ FP Sbjct: 605 NARAGDAPVGAQASAAP----TSVDGAPTSLGSPGLPAVSEQFKAQFP 648 Score = 53.1 bits (126), Expect = 3e-06 Identities = 78/368 (21%), Positives = 123/368 (33%), Gaps = 83/368 (22%) Query: 79 KPPKRPPIEASVHISQLP--QHPLTPAFMSPGKPEHLLEGSTWQLVDPMR-PGPSGSFVA 135 + P+RP +S S P H + + P+ LL G +P+ P + Sbjct: 551 RSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGD 610 Query: 136 PGLHPQSQLLPSHASIIPPE-DLPGVP------KVFVPRPSQVSLKPTEEAHKKERKPQK 188 + Q+ P+ P PG+P K P + T E K ++ + Sbjct: 611 APVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVEN 670 Query: 189 PGKYI-----CQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHA 243 K + C C R + S L+ H R+HTGERP+ C CG +F TK NL H H Sbjct: 671 IDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHR 730 Query: 244 HR---------------------IKAGLASGMGGEM--------YPHGLEMERIPGEEFE 274 + ++ + MGG++ + ++ E ++ Sbjct: 731 AKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMDSELAYDDKNA 790 Query: 275 EPTEGESTDSEEETSATSGHPAELSPRPKQPLLS-------------------------- 308 E D +E + + + P +PLLS Sbjct: 791 ETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSIAALENQMKMI 850 Query: 309 ---------SGLYSSGSHSSSHERCSLSQSSTAQSLED----PPPFVEPSSEHPLSHKPE 355 +GL S + S +R S SS LE P E SS LS P Sbjct: 851 DSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSSQALSPAPS 910 Query: 356 DTHTIKQK 363 + + + K Sbjct: 911 NGESFRSK 918 Score = 51.2 bits (121), Expect = 1e-05 Identities = 48/149 (32%), Positives = 65/149 (43%), Gaps = 24/149 (16%) Query: 1657 VSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPE 1716 +S+ + + A +P P G S S P L +PE ++ + + ER P Sbjct: 896 LSESSSSQALSPAPSNGESFRSKS----------PGLGAPEEPQE---IPLKTERPDSPA 942 Query: 1717 EDAPASQRGEPARIKIFEGGYKSNEEYVYVRGRGRGKYVCEECGIRCKKP----SMLKKH 1772 AP S G P R I E S + R RGK CG+ C KP S L+ H Sbjct: 943 A-APGSG-GAPGRAGIKEEAPFS----LLFLSRERGKCPSTVCGV-CGKPFACKSALEIH 995 Query: 1773 IRTHTDVRPYVCKHCHFAFKTKGNLTKHM 1801 R+HT RP+VC C T GNL +H+ Sbjct: 996 YRSHTKERPFVCALCRRGCSTMGNLKQHL 1024 Score = 47.8 bits (112), Expect = 1e-04 Identities = 22/46 (47%), Positives = 26/46 (56%) Query: 1756 CEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM 1801 C+ CG S L+ H RTHT +P+ C C AF TKGNL HM Sbjct: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHM 1160 Score = 47.4 bits (111), Expect = 2e-04 Identities = 21/50 (42%), Positives = 27/50 (54%) Query: 193 ICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242 +C C +P A S L+ H RSHT ERP+ C C T NL +H +H Sbjct: 978 VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 Score = 37.7 bits (86), Expect = 0.14 Identities = 81/339 (23%), Positives = 119/339 (35%), Gaps = 44/339 (12%) Query: 1837 EGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE---EESQDELSRPSSEAPPPG--PPHALR 1891 E + A F + + S S+ E E +E E ++ E EA P P R Sbjct: 84 EDAPAPPPEDFPEPSPASSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTR 143 Query: 1892 ADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVE 1951 A P P PP PA G +T + E L ++ +++ S G G Sbjct: 144 APRPPPAAPAPP-TPAYGAPSTNVT----LEALLSTKVAVAQFSQ------GARAAGGSG 192 Query: 1952 KDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKH----SLTKNDSSPQRCSPAREPQASA 2007 G A + P+ + + ++ + L + +L + SPA P A Sbjct: 193 AGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPG 252 Query: 2008 PSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLE-GTTDPGLPRY 2066 P+P L PG L G+P ++ P A LS+ E G + PG P Sbjct: 253 PAPSQL---PGLAALPLSAGAPAAAIAGSG--PAAPAAFEGAQPLSRPESGASTPGGPA- 306 Query: 2067 SPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSR 2126 P+ +P A +P AP P SA P PPA P LL Sbjct: 307 EPSAPAAPSAAPAPAAPAP-------APAPQSAASSQP-----QSASTPPALAPGSLLGA 354 Query: 2127 SPETCASPWKAESRSPSCSPGPAHPLSSR-----PFSAL 2160 +P + S S P P +++ P SAL Sbjct: 355 APGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSAL 393 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 71.2 bits (173), Expect = 1e-11 Identities = 185/906 (20%), Positives = 311/906 (34%), Gaps = 170/906 (18%) Query: 748 NLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFE 807 ++P + +SP+ K P R P PG ++ G + T+ Sbjct: 70 SVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTT------------- 116 Query: 808 KSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAH--SLQPKLVRQPNIQVPEILVTEEPD 865 D+ L G + H S+ P + + N V + + Sbjct: 117 --DTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFN 174 Query: 866 RPDTEPEPPPKEPEKTEEFQWPQRSQT----LAQLPAEKLPPKKKRLRLAEMAQSSGESS 921 D + + E T++ + Q+ Q + + P ++ PPK Sbjct: 175 PFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKP---------------- 218 Query: 922 FESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSH 981 +P + P ++ + G+ +S S ++ + K++ P KP+ T + Sbjct: 219 ----IPKQQGPGRDP-LQQDGTPKSISSQQPEKIKSQPPGTG-----KPIQGPTQTPQTD 268 Query: 982 H---PHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGP----------SAPAP 1028 H P R+ R ++Q+ V + S S G S P P Sbjct: 269 HAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP 328 Query: 1029 VAPPAR--------------VAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQP 1074 PPA+ V PP V+ ++PP L A Q++ +P Sbjct: 329 AKPPAQPSGLTKPLAQQPGTVKPP-------VQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381 Query: 1075 SSSKPSAKSSLSQISSAATSHGGPPG-GKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPL 1133 SS +P K+ L+Q PPG GK P Q GP P T+ + P+AQ P Sbjct: 382 SSEQPGPKA-LAQ----------PPGVGKTPAQQP---GPAKPPTQQVGT-PKPLAQQPG 426 Query: 1134 HEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAP---- 1189 + P P + Q Q PG+ P + QA S+ + P PPS P Sbjct: 427 LQSPAKAPGPTKTPVQ---QPGPGKIP---AQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480 Query: 1190 ---PLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQF 1246 P P +P PG P P P +QP P P S Sbjct: 481 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS--------- 531 Query: 1247 ALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLA 1306 Q PG + Q + P A S T ++ P V+P A P Sbjct: 532 --QQPGSAKPSAQQ-PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588 Query: 1307 LPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGT 1366 P C T + L VP + N T Q V G + L + +E Sbjct: 589 CPLCNTTELLLHVPEKANFNT--------CTECQTTVCSLCGFNPNPHLTEVKEWLCLNC 640 Query: 1367 TVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESI----------- 1415 + A ++ P PS + A T V + P+ + TS ++ Sbjct: 641 QMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEP 700 Query: 1416 ---------LSLEGSSSTAG----GSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKL 1462 +L GS S + + PA E ++ ++Q K ++ K + Sbjct: 701 KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPK---QP 757 Query: 1463 ELVKPCSVVLTSTEDGKRPEKSHLGNQGQG-RRELEMLSSLSSDPSDT-----KEIPPLP 1516 ++VKP + +++S+ +P+ Q Q + L + S+ PS + +++ P Sbjct: 758 KMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD 817 Query: 1517 HPALSHGTAPGSEA-LKEYPQPSGKPH-RRGLTPLSVKKEDSKEQPDLPSLAPPSSLPLS 1574 A+ P S++ + +P PS + ++ + P+ K+E K Q + P + P+ Sbjct: 818 SKAIPR---PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMS--PKPDAKPMP 872 Query: 1575 ETSSRP 1580 + S P Sbjct: 873 KGSPTP 878 Score = 58.9 bits (141), Expect = 6e-08 Identities = 105/449 (23%), Positives = 166/449 (36%), Gaps = 102/449 (22%) Query: 1971 PSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPR 2030 P ++ R PL + D +P+ S +++P+ PPG P +G P +P+ Sbjct: 220 PKQQGPGRDPL-------QQDGTPKSIS-SQQPEKIKSQPPGTG-KPIQG----PTQTPQ 266 Query: 2031 LQLSPLTLCPLGRELA-PRAHVLSKLEG-TTDPGLPRYS--PTRRWSPGQAESPPRSAPP 2086 + L PL R+ + P+ + G + P LP S P ++ +PG+ PP P Sbjct: 267 TDHAKL---PLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK---PPAQQPG 320 Query: 2087 GKWALAGPGSPSAGEHG--PGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSC 2144 + + GP P A G L P + PP P ++ P+ Sbjct: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP----------------GTTKPPAQ 364 Query: 2145 SPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQA 2204 GPA P + + S P Q +A +G Q Sbjct: 365 PLGPAKPPA-------------------QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP 405 Query: 2205 RPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTL 2264 P PT G T AQ+ G SP ++ + +PV + + Sbjct: 406 GPAKPPTQQVG----------------TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449 Query: 2265 SSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTH-SPCTPPDTLP---RPPQG 2320 ++ G P + GP +PP P PA+P P P PP P +PP Sbjct: 450 PAQQAG---PGKTSAQQTGPTKPPSQLP----GPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502 Query: 2321 RRAAQSWSPRLESPRAPTNPEPSAT-PPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQ 2379 + + P+ P P+ +P +T PP + S A+ SA+ P+ + + Q Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS----AKPSAQQPSPAK------PSAQ 552 Query: 2380 DSPKP---SGSGEPRAHPH-QPEDRVPPN 2404 S KP +GSG+P P P + PP+ Sbjct: 553 QSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581 Score = 57.0 bits (136), Expect = 2e-07 Identities = 178/861 (20%), Positives = 293/861 (34%), Gaps = 120/861 (13%) Query: 803 TSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTE 862 TS+ KS Q + + + P Q S P P P LV+QP + + Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAP-KQDLSKAPEP------KKPPPLVKQPTLHGSPSAKAK 721 Query: 863 EPDRPDTEPEP-PPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESS 921 +P D+ +P PPKEP E Q A + +K P + K ++ SS ++ Sbjct: 722 QPPEADSLSKPAPPKEPSVPSE-------QDKAPVADDK-PKQPKMVKPTTDLVSSSSAT 773 Query: 922 FESSVPLSRSPSQ---ESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTV 978 + +P S+ SQ ++ L S S G+ +P S + + +++ Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISH 833 Query: 979 P---SHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGP------SAPAPV 1029 P S +++ ++ P + + + +K GS + GP + P P Sbjct: 834 PGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQ 893 Query: 1030 APPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQIS 1089 P P E+ + F + S++ P+S+ P QE+ + S S S + Sbjct: 894 QSP---KPQEQSRRFSLNLGSITDAPKSQ----PTTPQETVTGKLFGFGASIFSQASNLI 946 Query: 1090 SAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPP-PVSLFSF 1148 S A GP GPG P +A P +Q P PP P Sbjct: 947 STA-GQPGPHSQSGPG---------APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996 Query: 1149 QHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPL---PPSLFQAPPLPLQPTVLH--PGQL 1203 + + + E + QA + + PP SL P + PT L P Sbjct: 997 KKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056 Query: 1204 HLPQLMPHPANIPFRQPPSFLPM--------------PYPTSSALSSGFFLPLQSQFAL- 1248 L NI + PP+F P P + + L Q+Q A+ Sbjct: 1057 STCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116 Query: 1249 -QLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSD-IRLPP---VAPPASSSAPTSAP 1303 QL GD+ P AP ++ + TE SS +PP + T A Sbjct: 1117 GQL-GDIRKMPP------APSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAE 1169 Query: 1304 PLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQI------------LVTQSQGSSA 1351 + L +T+ +P V T+ S + + L+ + + + Sbjct: 1170 KVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRS 1229 Query: 1352 TVALPKFEEP----------PSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVT 1401 P EE P T+ H++ ++EE+ P Sbjct: 1230 EEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGK 1289 Query: 1402 LPERKGTSLSSESILSL--EGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKAD 1459 P+ K L S + SL E +T ++ P + +E ++K KE++ S Sbjct: 1290 QPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTS 1349 Query: 1460 EKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQ--GRRELEMLSSLSSD-------PSDTK 1510 + P L+ T S LG E ++L L D PS Sbjct: 1350 SSQQPKSPQG--LSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPS 1407 Query: 1511 EIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSS 1570 ++ L LS A S E + +PH V E K+Q SL+ Sbjct: 1408 DLAKLESTVLSILEAQASTLADEKSEKKTQPH-------EVSPEQPKDQEKTQSLSETLE 1460 Query: 1571 LPLSETSSRPAKSQEGTDSKK 1591 + +SE + ++ + KK Sbjct: 1461 ITISEEEIKESQEERKDTFKK 1481 Score = 53.1 bits (126), Expect = 3e-06 Identities = 180/827 (21%), Positives = 265/827 (32%), Gaps = 129/827 (15%) Query: 673 KPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFES 732 KPI T T Q +H T + +R + SL +PP + Sbjct: 256 KPIQGPTQTP------QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309 Query: 733 TKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKP------------ 780 T PG A + +S PA+P L P QP T KP Sbjct: 310 T------PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363 Query: 781 -----------GSGSESGKERRTTSKEISVIQHT--SSFEKSDSLEQPSGLEGEDKPLAQ 827 +GSE + K ++ + ++ + P+ G KPLAQ Sbjct: 364 QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423 Query: 828 FP---SPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEP-------EPPPKE 877 P SP AP QP + P Q + + P P +PPP++ Sbjct: 424 QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQ 483 Query: 878 PEKTE-EFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPS--Q 934 P + Q P ++ +Q P PP ++ Q G + S P S PS Q Sbjct: 484 PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543 Query: 935 ESNVSLSGSSRSASFERDDHGKAEAP---SPSSDMRPK--------PLGTHMLTVPSHHP 983 S S + + GK P SPS+ P PL + + H P Sbjct: 544 PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPL-CNTTELLLHVP 602 Query: 984 HAREMRRSASEQSP-----NVSHSAHMTETRSKSFDYGSL--SLTGPSAPAPVAP-PARV 1035 Q+ + + H+TE + + +L G AP P +P P Sbjct: 603 EKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLK 662 Query: 1036 APPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSH 1095 P + + + + + + APK + S+ P+P P K S +A + Sbjct: 663 TAPVTTTSAVSKSSPQPQQTSPKKDAAPK-QDLSKAPEPKKPPPLVKQPTLHGSPSAKAK 721 Query: 1096 GGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLV--- 1152 PP + PP P+VP + PVA + + P L S Sbjct: 722 -QPPEADSLSKPAPPKEPSVPSEQD----KAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776 Query: 1153 ---------QHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPT--VLHP- 1200 Q E +P + A S S P + + P +A P P + + HP Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPS-QSFPPTGEKVSPFDSKAIPRPASDSKIISHPG 835 Query: 1201 ------GQLHLPQLM----PHPANIPFRQPPSFLPM----PYPTSSALSSGFFLPLQSQ- 1245 GQ + + P A P PM P P ++G +P Q Sbjct: 836 PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQS 895 Query: 1246 ---------FALQLPGDVESHLPQIKTSLAPLATGSA---GLSPSTEYSSDIRLPPVAPP 1293 F+L L G + T+ TG G S ++ S+ I P Sbjct: 896 PKPQEQSRRFSLNL-GSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGP 954 Query: 1294 ASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATV 1353 S S P AP PA P Q S G A I V + + A Sbjct: 955 HSQSGP-GAPMKQAPAPSQ-------PPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAE 1006 Query: 1354 AL-PKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVP 1399 L PK E+ P+ T + S +E Q PT + P Sbjct: 1007 KLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053 Score = 52.4 bits (124), Expect = 5e-06 Identities = 136/588 (23%), Positives = 201/588 (34%), Gaps = 103/588 (17%) Query: 1865 EDEEESQDELSRPSSEAPPPGPPHALRAD---SSPILGPQPPDAPASGTEATRGSSVSEA 1921 E + S S+P + P PG P A + S P GP P A SG Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP--GPAKPPAQPSGLTKPLAQQPGTV 349 Query: 1922 ERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPL 1981 + PG PLG + S KP S + P +A ++PP Sbjct: 350 K---------PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ----PGPKALAQPPG 396 Query: 1982 ARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPL 2041 K + Q+ PA+ P +P L PG P +P +P+ Sbjct: 397 VGK-------TPAQQPGPAKPPTQQVGTPKPLAQQPGLQS---PAKAPGPTKTPVQQPGP 446 Query: 2042 GRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGE 2101 G+ A +A T P P P++ PG A+ PP+ P K PGS Sbjct: 447 GKIPAQQAGPGKTSAQQTGPTKP---PSQL--PGPAKPPPQQPGPAKPPPQQPGSAKPPS 501 Query: 2102 HGPGLGLDPRVLFPPAPLPHKLLSRSPETCASP-WKAESRSPSC-SPGPAHP---LSSRP 2156 PG P P P P K + P + P + S PS P PA P S++P Sbjct: 502 QQPGSTKPP----PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557 Query: 2157 FSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQM-VQARPGAHPTLLPG 2215 S G L + + P SQ L + CPL + + V + + Sbjct: 558 VSQTGS--GKPLQPPTVSPSAKQP-PSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQ 614 Query: 2216 PTAAWVSGFSGGGSDLTGARE-----AQER----GRWSPTESSS---------ASVSPVA 2257 T + GF+ LT +E Q + G +P SS + S V+ Sbjct: 615 TTVCSLCGFN-PNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVS 673 Query: 2258 KVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGT--GAP-------------AEPT 2302 K S + + PK+ P +PP T G+P ++P Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733 Query: 2303 PTHSPCTP--------PDTLPRPPQGRR--------AAQSWSPRLESPRAPTNPEPSATP 2346 P P P D P+ P+ + ++ + P + S + + E TP Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793 Query: 2347 PLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHP 2394 PL S A+ S FP +S P + P+P+ + +HP Sbjct: 794 PLKTDS-----AKPSQSFPPTGEKVS--PFDSKAIPRPASDSKIISHP 834 Score = 50.8 bits (120), Expect = 2e-05 Identities = 245/1192 (20%), Positives = 368/1192 (30%), Gaps = 262/1192 (21%) Query: 30 SVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEAS 89 SV S+P P + P Q QP PG + G + + Q P +PP + S Sbjct: 293 SVKPSLPSPS-------KPPIQ-----QPTPGKPPAQQPGHE----KSQPGPAKPPAQPS 336 Query: 90 VHISQLPQHPLT-------------PAF-MSPGKPEHLLEGSTWQLVDPMRPGPSGSFVA 135 L Q P T PA + P KP GS + +PGP Sbjct: 337 GLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGS--EKPSSEQPGPKALAQP 394 Query: 136 PGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQ 195 PG+ P A PP G PK +P S K + PGK Q Sbjct: 395 PGVGKTPAQQPGPAK--PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452 Query: 196 YCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMG 255 K S Q + P P P + A S Sbjct: 453 QAGP--GKTSAQQTGPTKPPSQLPGPAKP------PPQQPGPAKPPPQQPGSAKPPSQQP 504 Query: 256 GEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGLYSSG 315 G P + PG P + S T S P P +QP S Sbjct: 505 GSTKPPPQQ----PGPAKPSPQQPGS------TKPPSQQPGSAKPSAQQP-------SPA 547 Query: 316 SHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSH-KPEDTHTIKQKLALRLSERKKV 374 S+ +SQ+ + + L+ PP V PS++ P S P+ + L L Sbjct: 548 KPSAQQSTKPVSQTGSGKPLQ--PPTVSPSAKQPPSQGLPKTICPLCNTTELLLH----- 600 Query: 375 IDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTA 434 + E+A + ++ T + +P T K + + +G A + Sbjct: 601 VPEKANFNTCTECQT-----TVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPV-P 654 Query: 435 TSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRR 494 +S QP L + S V S P+ Q TS P++ LS+ Sbjct: 655 SSPQPKLKTAPVTTTSAVSKSSPQPQ----------------QTSPKKDAAPKQ-DLSKA 697 Query: 495 SSMESPKSSLYREPL--SSHSEKTK--PEQSLLSLQHPPSTAPPVP-------------- 536 + P L ++P S S K K PE LS PP P VP Sbjct: 698 PEPKKP-PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK-EPSVPSEQDKAPVADDKPK 755 Query: 537 ----LLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKR--- 589 + + + S++ + P P S + T + S+ S P ++ Sbjct: 756 QPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP 815 Query: 590 --QPAIELPLGGEYSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNI 647 AI P PGPSS+ K D V+ KE +TK K Sbjct: 816 FDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD-------- 867 Query: 648 CGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTL 707 AKP+ G+ T P + + P Q Sbjct: 868 ------------------------AKPMPKGSPTPPGPRPTAGQTVPTPQQS-------- 895 Query: 708 ELTPLRKRRKEKSLGDEEEPPAFESTKSQ---------FGSPGPSDAARNLPLESTKSP- 757 + RR +LG + P + T Q FG+ S A+ + P Sbjct: 896 PKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPH 955 Query: 758 AEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSG 817 ++ P + P QP T + G +G+ +K I V + T + ++ LE + Sbjct: 956 SQSGPGAPMKQAPAPSQPPTSQ-GPPKSTGQAPPAPAKSIPVKKETKA-PAAEKLEPKAE 1013 Query: 818 LEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEP------ 871 K PPP +S L +P V + + P T P Sbjct: 1014 QAPTVKRTETEKKPPPIKDSKS-------LTAEPQKAVLPTKLEKSPKPESTCPLCKTEL 1066 Query: 872 ----EPPPK-------------------EPEKTEEFQW------PQRSQTLAQLPAEKLP 902 + PP P TE +W QR+ + K+P Sbjct: 1067 NIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP 1126 Query: 903 PKKKRLRLAEMAQSSGESSFESSVP----LSRSPSQE-----SNVSLSGSSRSASFE--- 950 P + + M + SS +++VP L + QE V L + S E Sbjct: 1127 PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIP 1186 Query: 951 -------RDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSA 1003 + + K E S+ KPL +P E + + E+ P + Sbjct: 1187 PMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIP------EEEKIRSEEKKPLLEEKK 1240 Query: 1004 HMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAP 1063 E + + P A+ + PE +K L++ + E VAP Sbjct: 1241 PTPEDKK------------------LLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAP 1282 Query: 1064 KGRQESEEPQ------PSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRP 1109 K QE ++PQ PS + S + + PP P Q P Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP 1334 Score = 47.4 bits (111), Expect = 2e-04 Identities = 204/1046 (19%), Positives = 347/1046 (33%), Gaps = 163/1046 (15%) Query: 26 AIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPP 85 A Q + S PG Q+ ++ A Q PG +S + G + Q P K PP Sbjct: 422 AQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP 481 Query: 86 IEASVHISQLPQHPLTPAFMSPG--KPEHLLEGSTWQLVDPMRPGPS-------GSFVAP 136 + P P PG KP GST P +PGP+ GS P Sbjct: 482 QQPG---------PAKPPPQQPGSAKPPSQQPGST--KPPPQQPGPAKPSPQQPGSTKPP 530 Query: 137 GLHP----QSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKY 192 P S PS A + V + +P Q PT K+ Q K Sbjct: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ---PPTVSPSAKQPPSQGLPKT 587 Query: 193 ICQYCSRPCAKPSVLQK-HIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLA 251 IC C+ V +K + + T + C CGF+ N + + + Sbjct: 588 ICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN----PNPHLTEVKEWLCLNCQMK 643 Query: 252 SGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGL 311 +GG++ P +P P T TSA S + SP+P+Q Sbjct: 644 RALGGDLAP-------VP----SSPQPKLKTAPVTTTSAVS----KSSPQPQQT------ 682 Query: 312 YSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEH----PLSHKPEDTHTI------K 361 S + S A + PPP V+ + H + +P + ++ K Sbjct: 683 ------SPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK 736 Query: 362 QKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGK 421 + ++ V D++ K +T+ S SA + P++ +S AE Sbjct: 737 EPSVPSEQDKAPVADDKPKQPKMVKPTTD---LVSSSSATTKPDIPSSKVQSQAE----- 788 Query: 422 CGRIGQRTAMLTATSTQP--LLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTS 479 + T L S +P P + E ++PR I + Sbjct: 789 ----EKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844 Query: 480 EIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLR 539 ++D V+ + ++ M SPK P S + + ++ P + P R Sbjct: 845 QVDPVQKKEEPKKAQTKM-SPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSR 903 Query: 540 SHSMPSAACT------ISTPHHPFRGS-YSFDDHITD------SEALSHSSHVFTSHPRM 586 S+ + T +TP G + F I S A H + Sbjct: 904 RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963 Query: 587 LKRQPAIELPLGGEYSSEEPG----------PSSKDTASKPSDEVEP--------KESEL 628 +K+ PA P + + G P K+T + ++++EP K +E Sbjct: 964 MKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTET 1023 Query: 629 TKKTKKGLKTKGVIYECN--ICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAE 686 KK +K + E + + +K E+ +EL I +T E + Sbjct: 1024 EKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECK 1083 Query: 687 KSQIEHEPWSQMMHY-KLGTTLELTPLRKRRKEKSLGDEEEPPAFESTKSQFGSPGPSDA 745 ++ H ++ L L +R LGD + P S P P+++ Sbjct: 1084 NQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTES 1143 Query: 746 A----------RNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSK 795 + + + + + E K + T + P + + +E + Sbjct: 1144 SSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKD 1203 Query: 796 EISVIQHTSSFEKSDSL--EQPSGLEGEDKPLAQFPSPPP-----APHGR-SAHSLQPKL 847 + S +Q + L E+ E KPL + P P P + SA Q Sbjct: 1204 KASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD 1263 Query: 848 VRQPNIQVPEILV--------TEEPDRPDTE--------PEPPPKEPEKTEEFQWPQRSQ 891 + + +Q+ E + +E +P T+ P+ PKE +KT + Q Sbjct: 1264 LLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQP 1323 Query: 892 TLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLS-GSSRS---- 946 P + P K+K + + + +S +S LS + +S S G S Sbjct: 1324 PCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPT 1383 Query: 947 ------ASFERDDHGKAEAPSPSSDM 966 ++D + +PS SD+ Sbjct: 1384 DEKDILKGLKKDSFSQESSPSSPSDL 1409 Score = 43.5 bits (101), Expect = 0.003 Identities = 142/626 (22%), Positives = 218/626 (34%), Gaps = 132/626 (21%) Query: 1873 ELSRPSSEAPPPG---PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSC 1929 ++ P A PG P A +P+ P P PA +A G + ++ T Sbjct: 414 QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ--QAGPGKTSAQQTGPTKPPS 471 Query: 1930 SMSSQSMPGLPWLGPAPL-----GSVEKDTGSALSYKPV---------SPRRPWS---PS 1972 + + P GPA GS + + S KP SP++P S PS Sbjct: 472 QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531 Query: 1973 KEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQ 2032 ++ GS P A++ S K S+ Q P + + P P V P P Q Sbjct: 532 QQPGSAKPSAQQPSPAK-PSAQQSTKPVSQTGSGKPLQPPT-VSPS-------AKQPPSQ 582 Query: 2033 LSPLTLCPLGRELAPRAHVLSKLEGTT--------------DPGLPRYSPTRRWSPGQAE 2078 P T+CPL HV K T +P P + + W + Sbjct: 583 GLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPN-PHLTEVKEWLCLNCQ 641 Query: 2079 SPPRSAPPGKWALAGPGSPSAGEHGPGLGLDP----RVLFPPAPLPHKLLSRSPETCASP 2134 K AL G +P P L P + +P P + SP+ A+P Sbjct: 642 M--------KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQT---SPKKDAAP 690 Query: 2135 WKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLI 2194 + S++P P PL +P HG A+ ++ P + L++ P Sbjct: 691 KQDLSKAPEPKKPP--PLVKQP-----TLHGSPSAKAKQ------PPEADSLSKPAPPKE 737 Query: 2195 PIGGIQMVQARPGAHPTLLPG---PTAAWVSGFSGGGS-DLTGAR-EAQERGRWSP---T 2246 P + +A P PT VS S D+ ++ ++Q + +P T Sbjct: 738 PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKT 797 Query: 2247 ESSSASVS--PVA-KVSKFTL------------------SSELEGGDY-----PKERERT 2280 +S+ S S P KVS F SSE +G KE + Sbjct: 798 DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857 Query: 2281 GGGPGRP-PDWTPHGTGAPAE--PTPTHSPCTP-PDTLPRP-PQGRRAAQSWSPRLESPR 2335 P PD P G+P P PT P P P+P Q RR + + ++P+ Sbjct: 858 AQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK 917 Query: 2336 A-PTNPEPSATPPL---------------DRSSSVGCLAEASARFPARTRNLSGEPRTRQ 2379 + PT P+ + T L + G +++ P + +P T Q Sbjct: 918 SQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQ 977 Query: 2380 DSPKPSGSGEP---RAHPHQPEDRVP 2402 PK +G P ++ P + E + P Sbjct: 978 GPPKSTGQAPPAPAKSIPVKKETKAP 1003 Score = 43.5 bits (101), Expect = 0.003 Identities = 155/751 (20%), Positives = 250/751 (33%), Gaps = 117/751 (15%) Query: 228 SFKTKSNLYKHRKSHAHRIKAGLASGMGGEMYPH-----GLEMERIPGEEFEEPTEGEST 282 + K+ +Y+ H+ KA A+ E++ G+ +E E E T S Sbjct: 1910 ALKSAEEMYEEMMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSV 1969 Query: 283 DSEEETSATSGHP-AELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPF 341 D T + + R ++ LS +Y + + + + S+ Sbjct: 1970 DGSLLTRQEEENGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDI 2029 Query: 342 VEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAE 401 V S P SH+ D T + E +K++D A Y + + Sbjct: 2030 VSSSFIIPESHEIVDLGT----MVTSTEEERKLLDADA------------AYEELMKRQQ 2073 Query: 402 QQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQV 461 Q++P ++ ++ + R + TS+ L S D S LS+P ++ Sbjct: 2074 MQLTPGSSPTQAPIGEDMTESTMDFDRMPDASLTSSV-LSGASLTDSTSSATLSIPDVKI 2132 Query: 462 IEHITKLITINEAVVD-TSEIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQ 520 +H + +E V D T EI + S + Y EP S S + P Sbjct: 2133 TQHFSTEEIEDEYVTDYTREIQEIIAHESLILT-----------YSEP--SESATSVPPS 2179 Query: 521 SLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHV- 579 PS V + + S T+ + + DSE +S S++ Sbjct: 2180 DT------PSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFP 2233 Query: 580 --FTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDTASKPSDEVEPK------------- 624 +P + P G S++ S D AS + V PK Sbjct: 2234 GSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDL 2293 Query: 625 ---ESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHT 681 E + KK KK G+I E Y+ + EA + T Sbjct: 2294 LISEKDPVKKAKKETGN-GIILEVL---EAYRDKKELEAER------------------T 2331 Query: 682 SPEAEKSQIEHEPWSQM---MHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFESTKSQFG 738 ++ +H P S + M +L TT T +EK + P S S Sbjct: 2332 KSSLSETVFDHPPSSVIALPMKEQLSTTY-FTSGETFGQEKPAS--QLPSGSPSVSSLPA 2388 Query: 739 SPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEIS 798 P P + +L + + P P P P P P P S + ++ + Sbjct: 2389 KPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASP 2448 Query: 799 VIQHTSSFEKSDSLEQPSGLEGEDKPLAQF--PSPPPAPHGRSAHSLQPKLVRQPNIQVP 856 V T F+ +LE + L P+ + +PPP P PK P+ Sbjct: 2449 VTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVP---------PK----PSSIPS 2495 Query: 857 EILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQS 916 ++ T P EP PP P+ PQ T Q P + + PK L L Sbjct: 2496 GLVFTHRP-----EPSKPPIAPKPV----IPQ-LPTTTQKPTD-IHPKPTGLSLTSSMTL 2544 Query: 917 SGESSFESSVPLSRSP-SQESNVSLSGSSRS 946 + +S + +P SP S SN S S+S Sbjct: 2545 NLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575 Score = 39.3 bits (90), Expect = 0.047 Identities = 117/557 (21%), Positives = 188/557 (33%), Gaps = 75/557 (13%) Query: 1181 LPPSLFQAPPLPLQPTVLHPGQLHLPQ-------LMPHPANIPFRQPPSFLPMPYPTSSA 1233 + P L Q PP P+ P PG+ L Q P I + P + P+ PT + Sbjct: 207 IKPPLQQQPPKPI-PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTP 265 Query: 1234 LSSGFFLPLQ--------SQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDI 1285 + LPLQ Q + V+ LP S P+ + G P+ + + Sbjct: 266 QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS--PSKPPIQQPTPGKPPAQQPGHEK 323 Query: 1286 RLP-PVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVT 1344 P P PPA S T PLA P T+ V P T P+ +Q T Sbjct: 324 SQPGPAKPPAQPSGLTK--PLAQQ--PGTVKPPVQPPGT-TKPPAQPLGPAKPPAQ--QT 376 Query: 1345 QSQGSSATVALPK-FEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLP 1403 S+ S+ PK +PP G T PGP+ PT + P L Sbjct: 377 GSEKPSSEQPGPKALAQPPGVGKTPAQQ------PGPAKP--------PTQQVGTPKPLA 422 Query: 1404 ERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLE 1463 ++ G L+ + G +K + G ++ + + ++ + Sbjct: 423 QQPG----------LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472 Query: 1464 LVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALSHG 1523 L P +P G ++ S P TK P P PA Sbjct: 473 LPGPA-----------KPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP 521 Query: 1524 TAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSSLPLSETSSRPAKS 1583 PGS S KP + +P + S +Q P S PL + P+ Sbjct: 522 QQPGSTKPPSQQPGSAKPSAQQPSP----AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAK 577 Query: 1584 QEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVS 1643 Q + P +TT L+ + + + C NP+L V Sbjct: 578 QPPSQGLPKTICPLCNTTE----LLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVK 633 Query: 1644 TKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLA 1703 L+ + K+ + + + ++P P+ + P ++ P SP +KD A Sbjct: 634 EWLCLN-CQMKRALGGDLAPVPSSPQPKL-KTAPVTTTSAVSKSSPQPQQTSP--KKD-A 688 Query: 1704 RVEKEEERRGEPEEDAP 1720 +++ + EP++ P Sbjct: 689 APKQDLSKAPEPKKPPP 705 Score = 38.1 bits (87), Expect = 0.11 Identities = 181/856 (21%), Positives = 289/856 (33%), Gaps = 138/856 (16%) Query: 1 MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFP 60 +DP Q + KKA+ K K +A S P PG A Q P PQ P Sbjct: 846 VDPVQKKEEPKKAQ---TKMSPKPDAKPMPKGSPTP-PGPRPTAGQTVPT-----PQQSP 896 Query: 61 GPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQL---------PQHPLTPAFMSPGKPE 111 P R S P +P +L L PG Sbjct: 897 KPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHS 956 Query: 112 HLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVP-KVFVPRPSQ 170 G+ PM+ P AP P SQ P PP +P K P+ Sbjct: 957 QSGPGA------PMKQAP-----APSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAA 1005 Query: 171 VSLKP------TEEAHKKERKPQKPGKYICQYCSRP--CAKPSVLQKHIRSHTGERPYPC 222 L+P T + + E+KP P K + P P+ L+K P P Sbjct: 1006 EKLEPKAEQAPTVKRTETEKKPP-PIKDSKSLTAEPQKAVLPTKLEKS--------PKPE 1056 Query: 223 GPCGFSFKTKSNLYKHRKSHAH---RIKAGLASGMGGEMYPHGLEMER--IPGEEFEEPT 277 C KT+ N+ + + K + + G PH E++ + + Sbjct: 1057 STCPLC-KTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAI 1115 Query: 278 EGESTDSEEETSATSGHPAELSPRPKQ---------PLLSSGLYSSGSHSSSHERCSLSQ 328 G+ D + A SG A P P + P + + E+ L + Sbjct: 1116 SGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEK 1175 Query: 329 SSTAQSLEDPPPFV-----------EPSSEHPLSHK---PEDTHTIKQKLALRLSERKKV 374 S+E PP V E L K PE+ I ++ +R E+K + Sbjct: 1176 VKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPL 1235 Query: 375 IDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKC-GRIGQRTAMLT 433 ++E+ K E +++ + E+Q + KS +I K GR+ +T Sbjct: 1236 LEEKKPTPEDKKLLPE----AKTSAPEEQ---KHDLLKSQVQIAEEKLEGRVAPKTVQ-- 1286 Query: 434 ATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSR 493 QP + E PS P S+P+ + TK I T++ D V+P + Sbjct: 1287 -EGKQPQTKM--EGLPSGTPQSLPKED--DKTTKTIKEQPQPPCTAKPDQVEPGK----E 1337 Query: 494 RSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTP 553 ++ E KS +S S++ K Q L + S S+ I T Sbjct: 1338 KTEKEDDKSD------TSSSQQPKSPQGLSDTGYSSDGI-------SSSLGEIPSLIPTD 1384 Query: 554 HHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDT 613 D +S S S + K + + L + S+ S K T Sbjct: 1385 EKDILKGLKKDSFSQESSPSSPSD--------LAKLESTVLSILEAQASTLADEKSEKKT 1436 Query: 614 ASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAK 673 +PK+ E T+ + L+ I E I ++ +++D + KK ++ +K Sbjct: 1437 QPHEVSPEQPKDQEKTQSLSETLEI--TISEEEIKESQEERKDTF---KKDSQQDIPSSK 1491 Query: 674 PISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFEST 733 S + EP+ + + + E +P+ +R++ S+G ++ Sbjct: 1492 D---HKEKSEFVDDITTRREPYDSV---EESSESENSPVPQRKRRTSVGSSSS-DEYKQE 1544 Query: 734 KSQFGSPGPSDAARNLPLE-STKSPAEPSK-------SVPSLEGPTGFQPRTPKPGSGS- 784 SQ GS D R +E S A S+ + + T Q + G G Sbjct: 1545 DSQ-GSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKI 1603 Query: 785 ESGKERRTTSKEISVI 800 +GK RR T K + I Sbjct: 1604 TAGKHRRLTRKSSTSI 1619 Score = 36.2 bits (82), Expect = 0.40 Identities = 57/223 (25%), Positives = 82/223 (36%), Gaps = 29/223 (13%) Query: 1217 FRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLS 1276 F PPS + + P LS+ +F ++ F + P S LP S++ L Sbjct: 2340 FDHPPSSV-IALPMKEQLSTTYFTSGET-FGQEKPA---SQLPSGSPSVSSLPAKPRPFF 2394 Query: 1277 PSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDT--------MVSLVVPVRVQTNMP 1328 S+ + PP PP P PP P P T L V V T P Sbjct: 2395 RSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454 Query: 1329 SYGSAMYTTLSQILVTQSQGSSATVALPKFEEP-PSKGTTVCGADVHEVGPGPSGLSEEQ 1387 + + TTL V +S G T P P K +++ V P PS + Sbjct: 2455 LFDAV--TTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPS-----K 2507 Query: 1388 SRAFPTPYL-RVPVTL-------PERKGTSLSSESILSLEGSS 1422 P P + ++P T P+ G SL+S L+L S+ Sbjct: 2508 PPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSA 2550 Score = 35.0 bits (79), Expect = 0.89 Identities = 86/360 (23%), Positives = 129/360 (35%), Gaps = 83/360 (23%) Query: 1107 DRPPLGP-TVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFST 1165 D PP +P E L + +T EKP P S L P + FF + Sbjct: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSL----PAKPRPFFRS 2396 Query: 1166 QAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLP 1225 ++ + + P PP PP PP P P PP P Sbjct: 2397 SSLD-ISAQPPPPPPPPP-----PPPPPPP------------------------PPPPPP 2426 Query: 1226 MPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDI 1285 +P PTS + LP + + + P + L T+L A + P T + Sbjct: 2427 LPPPTSPKPT---ILP-KKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT-- 2480 Query: 1286 RLPPVAPPASSSAPT----------SAPPLA-LPACPDTMVSLVVPVRVQTNMPSYGSAM 1334 PP PP SS P+ S PP+A P P + P + G ++ Sbjct: 2481 TAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPK--PTGLSL 2538 Query: 1335 YTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTP 1394 ++++ LVT SA LP P + P + S S++ Sbjct: 2539 TSSMTLNLVT-----SADYKLPSPTSP--------------LSPHSNKSSPRFSKSLTET 2579 Query: 1395 YLRVPVTLPERKGT---SLSSESILSLE-GSSSTAGGSKR----VLSPAGSLELTMETQQ 1446 Y V +TLP GT S +S++I S GS S S V+ P ++E+ + ++Q Sbjct: 2580 Y--VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQ 2637 Score = 34.7 bits (78), Expect = 1.2 Identities = 46/161 (28%), Positives = 60/161 (37%), Gaps = 26/161 (16%) Query: 2245 PTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPT 2304 P+ S S S P AK F SS L+ P P PP P P P P Sbjct: 2377 PSGSPSVSSLP-AKPRPFFRSSSLDISAQPP--------PPPPPPPPP-----PPPPPPP 2422 Query: 2305 HSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARF 2364 P PP T P+P + P+ + A +P +ATP D +++ A + Sbjct: 2423 PPPPLPPPTSPKP--------TILPKKKLTVA--SPVTTATPLFDAVTTLETTAVLRSNG 2472 Query: 2365 PARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPPNA 2405 TR + P PKPS H+PE PP A Sbjct: 2473 LPVTRICTTAP--PPVPPKPSSIPSGLVFTHRPEPSKPPIA 2511 Score = 34.3 bits (77), Expect = 1.5 Identities = 38/172 (22%), Positives = 64/172 (37%), Gaps = 19/172 (11%) Query: 1860 DEDEDEDEEESQDELSRPSSEAPPP----GPPHALRADSSPILGPQPPDAP----ASGTE 1911 + D D + S P + P G LRADS+ L P PP +P + + Sbjct: 3570 EADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISP 3629 Query: 1912 ATRGSSVSEA----ERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRR 1967 + G ++ A E+ S P + + PA + + + +S + Sbjct: 3630 LSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPA------SPKTAKMMQRSMSDPK 3683 Query: 1968 PWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPA-REPQASAPSPPGLHVDPG 2018 P SP+ + SR P T S S A ++ + + P+PP + G Sbjct: 3684 PLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTG 3735 Score = 33.1 bits (74), Expect = 3.4 Identities = 35/172 (20%), Positives = 56/172 (32%), Gaps = 14/172 (8%) Query: 1877 PSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSM 1936 P PPP PP L +SP P + T + + +A ++ + S + Sbjct: 2414 PPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGL 2473 Query: 1937 PGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQR 1996 P AP PV P+ PS + P K + PQ Sbjct: 2474 PVTRICTTAP--------------PPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQL 2519 Query: 1997 CSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPR 2048 + ++P P P GL + + + +L L P + +PR Sbjct: 2520 PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPR 2571 Score = 32.3 bits (72), Expect = 5.8 Identities = 65/285 (22%), Positives = 99/285 (34%), Gaps = 50/285 (17%) Query: 1329 SYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQS 1388 S S TT Q +V + QG + P ++ P K + GPG L ++ Sbjct: 182 SEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIP------KQQGPGRDPLQQD-- 233 Query: 1389 RAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQK 1448 GT S S + S G K + P T +T K Sbjct: 234 ------------------GTPKSISSQQPEKIKSQPPGTGKPIQGPT----QTPQTDHAK 271 Query: 1449 RVKEEEASKADEK-LELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPS 1507 + +AS+ K ++V+ SV + P K + G+ + S P Sbjct: 272 LPLQRDASRPQTKQADIVRGESVKPSLPS----PSKPPIQQPTPGKPPAQQPGHEKSQPG 327 Query: 1508 DTKEIPPLPHPALSHGTAPGSEALKEYPQPSG--KPHRRGLTPL------SVKKEDSKEQ 1559 K PP L+ A +K QP G KP + L P + ++ S EQ Sbjct: 328 PAK--PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ 385 Query: 1560 PDLPSLAPPSSLPLSETS----SRPAKSQEGTDSKKVLQFPSLHT 1600 P +LA P + + ++P Q GT K + Q P L + Sbjct: 386 PGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT-PKPLAQQPGLQS 429 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 71.2 bits (173), Expect = 1e-11 Identities = 185/906 (20%), Positives = 311/906 (34%), Gaps = 170/906 (18%) Query: 748 NLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFE 807 ++P + +SP+ K P R P PG ++ G + T+ Sbjct: 70 SVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTT------------- 116 Query: 808 KSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAH--SLQPKLVRQPNIQVPEILVTEEPD 865 D+ L G + H S+ P + + N V + + Sbjct: 117 --DTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFN 174 Query: 866 RPDTEPEPPPKEPEKTEEFQWPQRSQT----LAQLPAEKLPPKKKRLRLAEMAQSSGESS 921 D + + E T++ + Q+ Q + + P ++ PPK Sbjct: 175 PFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKP---------------- 218 Query: 922 FESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSH 981 +P + P ++ + G+ +S S ++ + K++ P KP+ T + Sbjct: 219 ----IPKQQGPGRDP-LQQDGTPKSISSQQPEKIKSQPPGTG-----KPIQGPTQTPQTD 268 Query: 982 H---PHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGP----------SAPAP 1028 H P R+ R ++Q+ V + S S G S P P Sbjct: 269 HAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP 328 Query: 1029 VAPPAR--------------VAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQP 1074 PPA+ V PP V+ ++PP L A Q++ +P Sbjct: 329 AKPPAQPSGLTKPLAQQPGTVKPP-------VQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381 Query: 1075 SSSKPSAKSSLSQISSAATSHGGPPG-GKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPL 1133 SS +P K+ L+Q PPG GK P Q GP P T+ + P+AQ P Sbjct: 382 SSEQPGPKA-LAQ----------PPGVGKTPAQQP---GPAKPPTQQVGT-PKPLAQQPG 426 Query: 1134 HEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAP---- 1189 + P P + Q Q PG+ P + QA S+ + P PPS P Sbjct: 427 LQSPAKAPGPTKTPVQ---QPGPGKIP---AQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480 Query: 1190 ---PLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQF 1246 P P +P PG P P P +QP P P S Sbjct: 481 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS--------- 531 Query: 1247 ALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLA 1306 Q PG + Q + P A S T ++ P V+P A P Sbjct: 532 --QQPGSAKPSAQQ-PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588 Query: 1307 LPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGT 1366 P C T + L VP + N T Q V G + L + +E Sbjct: 589 CPLCNTTELLLHVPEKANFNT--------CTECQTTVCSLCGFNPNPHLTEVKEWLCLNC 640 Query: 1367 TVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESI----------- 1415 + A ++ P PS + A T V + P+ + TS ++ Sbjct: 641 QMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEP 700 Query: 1416 ---------LSLEGSSSTAG----GSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKL 1462 +L GS S + + PA E ++ ++Q K ++ K + Sbjct: 701 KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPK---QP 757 Query: 1463 ELVKPCSVVLTSTEDGKRPEKSHLGNQGQG-RRELEMLSSLSSDPSDT-----KEIPPLP 1516 ++VKP + +++S+ +P+ Q Q + L + S+ PS + +++ P Sbjct: 758 KMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD 817 Query: 1517 HPALSHGTAPGSEA-LKEYPQPSGKPH-RRGLTPLSVKKEDSKEQPDLPSLAPPSSLPLS 1574 A+ P S++ + +P PS + ++ + P+ K+E K Q + P + P+ Sbjct: 818 SKAIPR---PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMS--PKPDAKPMP 872 Query: 1575 ETSSRP 1580 + S P Sbjct: 873 KGSPTP 878 Score = 58.9 bits (141), Expect = 6e-08 Identities = 105/449 (23%), Positives = 166/449 (36%), Gaps = 102/449 (22%) Query: 1971 PSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPR 2030 P ++ R PL + D +P+ S +++P+ PPG P +G P +P+ Sbjct: 220 PKQQGPGRDPL-------QQDGTPKSIS-SQQPEKIKSQPPGTG-KPIQG----PTQTPQ 266 Query: 2031 LQLSPLTLCPLGRELA-PRAHVLSKLEG-TTDPGLPRYS--PTRRWSPGQAESPPRSAPP 2086 + L PL R+ + P+ + G + P LP S P ++ +PG+ PP P Sbjct: 267 TDHAKL---PLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK---PPAQQPG 320 Query: 2087 GKWALAGPGSPSAGEHG--PGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSC 2144 + + GP P A G L P + PP P ++ P+ Sbjct: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP----------------GTTKPPAQ 364 Query: 2145 SPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQA 2204 GPA P + + S P Q +A +G Q Sbjct: 365 PLGPAKPPA-------------------QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP 405 Query: 2205 RPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTL 2264 P PT G T AQ+ G SP ++ + +PV + + Sbjct: 406 GPAKPPTQQVG----------------TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449 Query: 2265 SSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTH-SPCTPPDTLP---RPPQG 2320 ++ G P + GP +PP P PA+P P P PP P +PP Sbjct: 450 PAQQAG---PGKTSAQQTGPTKPPSQLP----GPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502 Query: 2321 RRAAQSWSPRLESPRAPTNPEPSAT-PPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQ 2379 + + P+ P P+ +P +T PP + S A+ SA+ P+ + + Q Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS----AKPSAQQPSPAK------PSAQ 552 Query: 2380 DSPKP---SGSGEPRAHPH-QPEDRVPPN 2404 S KP +GSG+P P P + PP+ Sbjct: 553 QSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581 Score = 57.0 bits (136), Expect = 2e-07 Identities = 178/861 (20%), Positives = 293/861 (34%), Gaps = 120/861 (13%) Query: 803 TSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTE 862 TS+ KS Q + + + P Q S P P P LV+QP + + Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAP-KQDLSKAPEP------KKPPPLVKQPTLHGSPSAKAK 721 Query: 863 EPDRPDTEPEP-PPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESS 921 +P D+ +P PPKEP E Q A + +K P + K ++ SS ++ Sbjct: 722 QPPEADSLSKPAPPKEPSVPSE-------QDKAPVADDK-PKQPKMVKPTTDLVSSSSAT 773 Query: 922 FESSVPLSRSPSQ---ESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTV 978 + +P S+ SQ ++ L S S G+ +P S + + +++ Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISH 833 Query: 979 P---SHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGP------SAPAPV 1029 P S +++ ++ P + + + +K GS + GP + P P Sbjct: 834 PGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQ 893 Query: 1030 APPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQIS 1089 P P E+ + F + S++ P+S+ P QE+ + S S S + Sbjct: 894 QSP---KPQEQSRRFSLNLGSITDAPKSQ----PTTPQETVTGKLFGFGASIFSQASNLI 946 Query: 1090 SAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPP-PVSLFSF 1148 S A GP GPG P +A P +Q P PP P Sbjct: 947 STA-GQPGPHSQSGPG---------APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996 Query: 1149 QHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPL---PPSLFQAPPLPLQPTVLH--PGQL 1203 + + + E + QA + + PP SL P + PT L P Sbjct: 997 KKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056 Query: 1204 HLPQLMPHPANIPFRQPPSFLPM--------------PYPTSSALSSGFFLPLQSQFAL- 1248 L NI + PP+F P P + + L Q+Q A+ Sbjct: 1057 STCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116 Query: 1249 -QLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSD-IRLPP---VAPPASSSAPTSAP 1303 QL GD+ P AP ++ + TE SS +PP + T A Sbjct: 1117 GQL-GDIRKMPP------APSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAE 1169 Query: 1304 PLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQI------------LVTQSQGSSA 1351 + L +T+ +P V T+ S + + L+ + + + Sbjct: 1170 KVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRS 1229 Query: 1352 TVALPKFEEP----------PSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVT 1401 P EE P T+ H++ ++EE+ P Sbjct: 1230 EEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGK 1289 Query: 1402 LPERKGTSLSSESILSL--EGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKAD 1459 P+ K L S + SL E +T ++ P + +E ++K KE++ S Sbjct: 1290 QPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTS 1349 Query: 1460 EKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQ--GRRELEMLSSLSSD-------PSDTK 1510 + P L+ T S LG E ++L L D PS Sbjct: 1350 SSQQPKSPQG--LSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPS 1407 Query: 1511 EIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSS 1570 ++ L LS A S E + +PH V E K+Q SL+ Sbjct: 1408 DLAKLESTVLSILEAQASTLADEKSEKKTQPH-------EVSPEQPKDQEKTQSLSETLE 1460 Query: 1571 LPLSETSSRPAKSQEGTDSKK 1591 + +SE + ++ + KK Sbjct: 1461 ITISEEEIKESQEERKDTFKK 1481 Score = 53.1 bits (126), Expect = 3e-06 Identities = 180/827 (21%), Positives = 265/827 (32%), Gaps = 129/827 (15%) Query: 673 KPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFES 732 KPI T T Q +H T + +R + SL +PP + Sbjct: 256 KPIQGPTQTP------QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309 Query: 733 TKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKP------------ 780 T PG A + +S PA+P L P QP T KP Sbjct: 310 T------PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363 Query: 781 -----------GSGSESGKERRTTSKEISVIQHT--SSFEKSDSLEQPSGLEGEDKPLAQ 827 +GSE + K ++ + ++ + P+ G KPLAQ Sbjct: 364 QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423 Query: 828 FP---SPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEP-------EPPPKE 877 P SP AP QP + P Q + + P P +PPP++ Sbjct: 424 QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQ 483 Query: 878 PEKTE-EFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPS--Q 934 P + Q P ++ +Q P PP ++ Q G + S P S PS Q Sbjct: 484 PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543 Query: 935 ESNVSLSGSSRSASFERDDHGKAEAP---SPSSDMRPK--------PLGTHMLTVPSHHP 983 S S + + GK P SPS+ P PL + + H P Sbjct: 544 PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPL-CNTTELLLHVP 602 Query: 984 HAREMRRSASEQSP-----NVSHSAHMTETRSKSFDYGSL--SLTGPSAPAPVAP-PARV 1035 Q+ + + H+TE + + +L G AP P +P P Sbjct: 603 EKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLK 662 Query: 1036 APPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSH 1095 P + + + + + + APK + S+ P+P P K S +A + Sbjct: 663 TAPVTTTSAVSKSSPQPQQTSPKKDAAPK-QDLSKAPEPKKPPPLVKQPTLHGSPSAKAK 721 Query: 1096 GGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLV--- 1152 PP + PP P+VP + PVA + + P L S Sbjct: 722 -QPPEADSLSKPAPPKEPSVPSEQD----KAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776 Query: 1153 ---------QHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPT--VLHP- 1200 Q E +P + A S S P + + P +A P P + + HP Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPS-QSFPPTGEKVSPFDSKAIPRPASDSKIISHPG 835 Query: 1201 ------GQLHLPQLM----PHPANIPFRQPPSFLPM----PYPTSSALSSGFFLPLQSQ- 1245 GQ + + P A P PM P P ++G +P Q Sbjct: 836 PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQS 895 Query: 1246 ---------FALQLPGDVESHLPQIKTSLAPLATGSA---GLSPSTEYSSDIRLPPVAPP 1293 F+L L G + T+ TG G S ++ S+ I P Sbjct: 896 PKPQEQSRRFSLNL-GSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGP 954 Query: 1294 ASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATV 1353 S S P AP PA P Q S G A I V + + A Sbjct: 955 HSQSGP-GAPMKQAPAPSQ-------PPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAE 1006 Query: 1354 AL-PKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVP 1399 L PK E+ P+ T + S +E Q PT + P Sbjct: 1007 KLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053 Score = 52.4 bits (124), Expect = 5e-06 Identities = 136/588 (23%), Positives = 201/588 (34%), Gaps = 103/588 (17%) Query: 1865 EDEEESQDELSRPSSEAPPPGPPHALRAD---SSPILGPQPPDAPASGTEATRGSSVSEA 1921 E + S S+P + P PG P A + S P GP P A SG Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP--GPAKPPAQPSGLTKPLAQQPGTV 349 Query: 1922 ERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPL 1981 + PG PLG + S KP S + P +A ++PP Sbjct: 350 K---------PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ----PGPKALAQPPG 396 Query: 1982 ARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPL 2041 K + Q+ PA+ P +P L PG P +P +P+ Sbjct: 397 VGK-------TPAQQPGPAKPPTQQVGTPKPLAQQPGLQS---PAKAPGPTKTPVQQPGP 446 Query: 2042 GRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGE 2101 G+ A +A T P P P++ PG A+ PP+ P K PGS Sbjct: 447 GKIPAQQAGPGKTSAQQTGPTKP---PSQL--PGPAKPPPQQPGPAKPPPQQPGSAKPPS 501 Query: 2102 HGPGLGLDPRVLFPPAPLPHKLLSRSPETCASP-WKAESRSPSC-SPGPAHP---LSSRP 2156 PG P P P P K + P + P + S PS P PA P S++P Sbjct: 502 QQPGSTKPP----PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557 Query: 2157 FSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQM-VQARPGAHPTLLPG 2215 S G L + + P SQ L + CPL + + V + + Sbjct: 558 VSQTGS--GKPLQPPTVSPSAKQP-PSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQ 614 Query: 2216 PTAAWVSGFSGGGSDLTGARE-----AQER----GRWSPTESSS---------ASVSPVA 2257 T + GF+ LT +E Q + G +P SS + S V+ Sbjct: 615 TTVCSLCGFN-PNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVS 673 Query: 2258 KVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGT--GAP-------------AEPT 2302 K S + + PK+ P +PP T G+P ++P Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733 Query: 2303 PTHSPCTP--------PDTLPRPPQGRR--------AAQSWSPRLESPRAPTNPEPSATP 2346 P P P D P+ P+ + ++ + P + S + + E TP Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793 Query: 2347 PLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHP 2394 PL S A+ S FP +S P + P+P+ + +HP Sbjct: 794 PLKTDS-----AKPSQSFPPTGEKVS--PFDSKAIPRPASDSKIISHP 834 Score = 50.8 bits (120), Expect = 2e-05 Identities = 245/1192 (20%), Positives = 368/1192 (30%), Gaps = 262/1192 (21%) Query: 30 SVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEAS 89 SV S+P P + P Q QP PG + G + + Q P +PP + S Sbjct: 293 SVKPSLPSPS-------KPPIQ-----QPTPGKPPAQQPGHE----KSQPGPAKPPAQPS 336 Query: 90 VHISQLPQHPLT-------------PAF-MSPGKPEHLLEGSTWQLVDPMRPGPSGSFVA 135 L Q P T PA + P KP GS + +PGP Sbjct: 337 GLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGS--EKPSSEQPGPKALAQP 394 Query: 136 PGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQ 195 PG+ P A PP G PK +P S K + PGK Q Sbjct: 395 PGVGKTPAQQPGPAK--PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452 Query: 196 YCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMG 255 K S Q + P P P + A S Sbjct: 453 QAGP--GKTSAQQTGPTKPPSQLPGPAKP------PPQQPGPAKPPPQQPGSAKPPSQQP 504 Query: 256 GEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGLYSSG 315 G P + PG P + S T S P P +QP S Sbjct: 505 GSTKPPPQQ----PGPAKPSPQQPGS------TKPPSQQPGSAKPSAQQP-------SPA 547 Query: 316 SHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSH-KPEDTHTIKQKLALRLSERKKV 374 S+ +SQ+ + + L+ PP V PS++ P S P+ + L L Sbjct: 548 KPSAQQSTKPVSQTGSGKPLQ--PPTVSPSAKQPPSQGLPKTICPLCNTTELLLH----- 600 Query: 375 IDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTA 434 + E+A + ++ T + +P T K + + +G A + Sbjct: 601 VPEKANFNTCTECQT-----TVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPV-P 654 Query: 435 TSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRR 494 +S QP L + S V S P+ Q TS P++ LS+ Sbjct: 655 SSPQPKLKTAPVTTTSAVSKSSPQPQ----------------QTSPKKDAAPKQ-DLSKA 697 Query: 495 SSMESPKSSLYREPL--SSHSEKTK--PEQSLLSLQHPPSTAPPVP-------------- 536 + P L ++P S S K K PE LS PP P VP Sbjct: 698 PEPKKP-PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK-EPSVPSEQDKAPVADDKPK 755 Query: 537 ----LLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKR--- 589 + + + S++ + P P S + T + S+ S P ++ Sbjct: 756 QPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP 815 Query: 590 --QPAIELPLGGEYSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNI 647 AI P PGPSS+ K D V+ KE +TK K Sbjct: 816 FDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD-------- 867 Query: 648 CGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTL 707 AKP+ G+ T P + + P Q Sbjct: 868 ------------------------AKPMPKGSPTPPGPRPTAGQTVPTPQQS-------- 895 Query: 708 ELTPLRKRRKEKSLGDEEEPPAFESTKSQ---------FGSPGPSDAARNLPLESTKSP- 757 + RR +LG + P + T Q FG+ S A+ + P Sbjct: 896 PKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPH 955 Query: 758 AEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSG 817 ++ P + P QP T + G +G+ +K I V + T + ++ LE + Sbjct: 956 SQSGPGAPMKQAPAPSQPPTSQ-GPPKSTGQAPPAPAKSIPVKKETKA-PAAEKLEPKAE 1013 Query: 818 LEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEP------ 871 K PPP +S L +P V + + P T P Sbjct: 1014 QAPTVKRTETEKKPPPIKDSKS-------LTAEPQKAVLPTKLEKSPKPESTCPLCKTEL 1066 Query: 872 ----EPPPK-------------------EPEKTEEFQW------PQRSQTLAQLPAEKLP 902 + PP P TE +W QR+ + K+P Sbjct: 1067 NIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP 1126 Query: 903 PKKKRLRLAEMAQSSGESSFESSVP----LSRSPSQE-----SNVSLSGSSRSASFE--- 950 P + + M + SS +++VP L + QE V L + S E Sbjct: 1127 PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIP 1186 Query: 951 -------RDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSA 1003 + + K E S+ KPL +P E + + E+ P + Sbjct: 1187 PMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIP------EEEKIRSEEKKPLLEEKK 1240 Query: 1004 HMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAP 1063 E + + P A+ + PE +K L++ + E VAP Sbjct: 1241 PTPEDKK------------------LLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAP 1282 Query: 1064 KGRQESEEPQ------PSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRP 1109 K QE ++PQ PS + S + + PP P Q P Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP 1334 Score = 47.4 bits (111), Expect = 2e-04 Identities = 204/1046 (19%), Positives = 347/1046 (33%), Gaps = 163/1046 (15%) Query: 26 AIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPP 85 A Q + S PG Q+ ++ A Q PG +S + G + Q P K PP Sbjct: 422 AQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP 481 Query: 86 IEASVHISQLPQHPLTPAFMSPG--KPEHLLEGSTWQLVDPMRPGPS-------GSFVAP 136 + P P PG KP GST P +PGP+ GS P Sbjct: 482 QQPG---------PAKPPPQQPGSAKPPSQQPGST--KPPPQQPGPAKPSPQQPGSTKPP 530 Query: 137 GLHP----QSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKY 192 P S PS A + V + +P Q PT K+ Q K Sbjct: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ---PPTVSPSAKQPPSQGLPKT 587 Query: 193 ICQYCSRPCAKPSVLQK-HIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLA 251 IC C+ V +K + + T + C CGF+ N + + + Sbjct: 588 ICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN----PNPHLTEVKEWLCLNCQMK 643 Query: 252 SGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGL 311 +GG++ P +P P T TSA S + SP+P+Q Sbjct: 644 RALGGDLAP-------VP----SSPQPKLKTAPVTTTSAVS----KSSPQPQQT------ 682 Query: 312 YSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEH----PLSHKPEDTHTI------K 361 S + S A + PPP V+ + H + +P + ++ K Sbjct: 683 ------SPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK 736 Query: 362 QKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGK 421 + ++ V D++ K +T+ S SA + P++ +S AE Sbjct: 737 EPSVPSEQDKAPVADDKPKQPKMVKPTTD---LVSSSSATTKPDIPSSKVQSQAE----- 788 Query: 422 CGRIGQRTAMLTATSTQP--LLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTS 479 + T L S +P P + E ++PR I + Sbjct: 789 ----EKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844 Query: 480 EIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLR 539 ++D V+ + ++ M SPK P S + + ++ P + P R Sbjct: 845 QVDPVQKKEEPKKAQTKM-SPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSR 903 Query: 540 SHSMPSAACT------ISTPHHPFRGS-YSFDDHITD------SEALSHSSHVFTSHPRM 586 S+ + T +TP G + F I S A H + Sbjct: 904 RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963 Query: 587 LKRQPAIELPLGGEYSSEEPG----------PSSKDTASKPSDEVEP--------KESEL 628 +K+ PA P + + G P K+T + ++++EP K +E Sbjct: 964 MKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTET 1023 Query: 629 TKKTKKGLKTKGVIYECN--ICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAE 686 KK +K + E + + +K E+ +EL I +T E + Sbjct: 1024 EKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECK 1083 Query: 687 KSQIEHEPWSQMMHY-KLGTTLELTPLRKRRKEKSLGDEEEPPAFESTKSQFGSPGPSDA 745 ++ H ++ L L +R LGD + P S P P+++ Sbjct: 1084 NQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTES 1143 Query: 746 A----------RNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSK 795 + + + + + E K + T + P + + +E + Sbjct: 1144 SSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKD 1203 Query: 796 EISVIQHTSSFEKSDSL--EQPSGLEGEDKPLAQFPSPPP-----APHGR-SAHSLQPKL 847 + S +Q + L E+ E KPL + P P P + SA Q Sbjct: 1204 KASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD 1263 Query: 848 VRQPNIQVPEILV--------TEEPDRPDTE--------PEPPPKEPEKTEEFQWPQRSQ 891 + + +Q+ E + +E +P T+ P+ PKE +KT + Q Sbjct: 1264 LLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQP 1323 Query: 892 TLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLS-GSSRS---- 946 P + P K+K + + + +S +S LS + +S S G S Sbjct: 1324 PCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPT 1383 Query: 947 ------ASFERDDHGKAEAPSPSSDM 966 ++D + +PS SD+ Sbjct: 1384 DEKDILKGLKKDSFSQESSPSSPSDL 1409 Score = 43.5 bits (101), Expect = 0.003 Identities = 142/626 (22%), Positives = 218/626 (34%), Gaps = 132/626 (21%) Query: 1873 ELSRPSSEAPPPG---PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSC 1929 ++ P A PG P A +P+ P P PA +A G + ++ T Sbjct: 414 QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ--QAGPGKTSAQQTGPTKPPS 471 Query: 1930 SMSSQSMPGLPWLGPAPL-----GSVEKDTGSALSYKPV---------SPRRPWS---PS 1972 + + P GPA GS + + S KP SP++P S PS Sbjct: 472 QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531 Query: 1973 KEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQ 2032 ++ GS P A++ S K S+ Q P + + P P V P P Q Sbjct: 532 QQPGSAKPSAQQPSPAK-PSAQQSTKPVSQTGSGKPLQPPT-VSPS-------AKQPPSQ 582 Query: 2033 LSPLTLCPLGRELAPRAHVLSKLEGTT--------------DPGLPRYSPTRRWSPGQAE 2078 P T+CPL HV K T +P P + + W + Sbjct: 583 GLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPN-PHLTEVKEWLCLNCQ 641 Query: 2079 SPPRSAPPGKWALAGPGSPSAGEHGPGLGLDP----RVLFPPAPLPHKLLSRSPETCASP 2134 K AL G +P P L P + +P P + SP+ A+P Sbjct: 642 M--------KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQT---SPKKDAAP 690 Query: 2135 WKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLI 2194 + S++P P PL +P HG A+ ++ P + L++ P Sbjct: 691 KQDLSKAPEPKKPP--PLVKQP-----TLHGSPSAKAKQ------PPEADSLSKPAPPKE 737 Query: 2195 PIGGIQMVQARPGAHPTLLPG---PTAAWVSGFSGGGS-DLTGAR-EAQERGRWSP---T 2246 P + +A P PT VS S D+ ++ ++Q + +P T Sbjct: 738 PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKT 797 Query: 2247 ESSSASVS--PVA-KVSKFTL------------------SSELEGGDY-----PKERERT 2280 +S+ S S P KVS F SSE +G KE + Sbjct: 798 DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857 Query: 2281 GGGPGRP-PDWTPHGTGAPAE--PTPTHSPCTP-PDTLPRP-PQGRRAAQSWSPRLESPR 2335 P PD P G+P P PT P P P+P Q RR + + ++P+ Sbjct: 858 AQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK 917 Query: 2336 A-PTNPEPSATPPL---------------DRSSSVGCLAEASARFPARTRNLSGEPRTRQ 2379 + PT P+ + T L + G +++ P + +P T Q Sbjct: 918 SQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQ 977 Query: 2380 DSPKPSGSGEP---RAHPHQPEDRVP 2402 PK +G P ++ P + E + P Sbjct: 978 GPPKSTGQAPPAPAKSIPVKKETKAP 1003 Score = 43.5 bits (101), Expect = 0.003 Identities = 155/751 (20%), Positives = 250/751 (33%), Gaps = 117/751 (15%) Query: 228 SFKTKSNLYKHRKSHAHRIKAGLASGMGGEMYPH-----GLEMERIPGEEFEEPTEGEST 282 + K+ +Y+ H+ KA A+ E++ G+ +E E E T S Sbjct: 1910 ALKSAEEMYEEMMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSV 1969 Query: 283 DSEEETSATSGHP-AELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPF 341 D T + + R ++ LS +Y + + + + S+ Sbjct: 1970 DGSLLTRQEEENGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDI 2029 Query: 342 VEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAE 401 V S P SH+ D T + E +K++D A Y + + Sbjct: 2030 VSSSFIIPESHEIVDLGT----MVTSTEEERKLLDADA------------AYEELMKRQQ 2073 Query: 402 QQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQV 461 Q++P ++ ++ + R + TS+ L S D S LS+P ++ Sbjct: 2074 MQLTPGSSPTQAPIGEDMTESTMDFDRMPDASLTSSV-LSGASLTDSTSSATLSIPDVKI 2132 Query: 462 IEHITKLITINEAVVD-TSEIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQ 520 +H + +E V D T EI + S + Y EP S S + P Sbjct: 2133 TQHFSTEEIEDEYVTDYTREIQEIIAHESLILT-----------YSEP--SESATSVPPS 2179 Query: 521 SLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHV- 579 PS V + + S T+ + + DSE +S S++ Sbjct: 2180 DT------PSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFP 2233 Query: 580 --FTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDTASKPSDEVEPK------------- 624 +P + P G S++ S D AS + V PK Sbjct: 2234 GSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDL 2293 Query: 625 ---ESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHT 681 E + KK KK G+I E Y+ + EA + T Sbjct: 2294 LISEKDPVKKAKKETGN-GIILEVL---EAYRDKKELEAER------------------T 2331 Query: 682 SPEAEKSQIEHEPWSQM---MHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFESTKSQFG 738 ++ +H P S + M +L TT T +EK + P S S Sbjct: 2332 KSSLSETVFDHPPSSVIALPMKEQLSTTY-FTSGETFGQEKPAS--QLPSGSPSVSSLPA 2388 Query: 739 SPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEIS 798 P P + +L + + P P P P P P P S + ++ + Sbjct: 2389 KPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASP 2448 Query: 799 VIQHTSSFEKSDSLEQPSGLEGEDKPLAQF--PSPPPAPHGRSAHSLQPKLVRQPNIQVP 856 V T F+ +LE + L P+ + +PPP P PK P+ Sbjct: 2449 VTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVP---------PK----PSSIPS 2495 Query: 857 EILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQS 916 ++ T P EP PP P+ PQ T Q P + + PK L L Sbjct: 2496 GLVFTHRP-----EPSKPPIAPKPV----IPQ-LPTTTQKPTD-IHPKPTGLSLTSSMTL 2544 Query: 917 SGESSFESSVPLSRSP-SQESNVSLSGSSRS 946 + +S + +P SP S SN S S+S Sbjct: 2545 NLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575 Score = 39.3 bits (90), Expect = 0.047 Identities = 117/557 (21%), Positives = 188/557 (33%), Gaps = 75/557 (13%) Query: 1181 LPPSLFQAPPLPLQPTVLHPGQLHLPQ-------LMPHPANIPFRQPPSFLPMPYPTSSA 1233 + P L Q PP P+ P PG+ L Q P I + P + P+ PT + Sbjct: 207 IKPPLQQQPPKPI-PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTP 265 Query: 1234 LSSGFFLPLQ--------SQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDI 1285 + LPLQ Q + V+ LP S P+ + G P+ + + Sbjct: 266 QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS--PSKPPIQQPTPGKPPAQQPGHEK 323 Query: 1286 RLP-PVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVT 1344 P P PPA S T PLA P T+ V P T P+ +Q T Sbjct: 324 SQPGPAKPPAQPSGLTK--PLAQQ--PGTVKPPVQPPGT-TKPPAQPLGPAKPPAQ--QT 376 Query: 1345 QSQGSSATVALPK-FEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLP 1403 S+ S+ PK +PP G T PGP+ PT + P L Sbjct: 377 GSEKPSSEQPGPKALAQPPGVGKTPAQQ------PGPAKP--------PTQQVGTPKPLA 422 Query: 1404 ERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLE 1463 ++ G L+ + G +K + G ++ + + ++ + Sbjct: 423 QQPG----------LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472 Query: 1464 LVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALSHG 1523 L P +P G ++ S P TK P P PA Sbjct: 473 LPGPA-----------KPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP 521 Query: 1524 TAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSSLPLSETSSRPAKS 1583 PGS S KP + +P + S +Q P S PL + P+ Sbjct: 522 QQPGSTKPPSQQPGSAKPSAQQPSP----AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAK 577 Query: 1584 QEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVS 1643 Q + P +TT L+ + + + C NP+L V Sbjct: 578 QPPSQGLPKTICPLCNTTE----LLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVK 633 Query: 1644 TKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLA 1703 L+ + K+ + + + ++P P+ + P ++ P SP +KD A Sbjct: 634 EWLCLN-CQMKRALGGDLAPVPSSPQPKL-KTAPVTTTSAVSKSSPQPQQTSP--KKD-A 688 Query: 1704 RVEKEEERRGEPEEDAP 1720 +++ + EP++ P Sbjct: 689 APKQDLSKAPEPKKPPP 705 Score = 38.1 bits (87), Expect = 0.11 Identities = 181/856 (21%), Positives = 289/856 (33%), Gaps = 138/856 (16%) Query: 1 MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFP 60 +DP Q + KKA+ K K +A S P PG A Q P PQ P Sbjct: 846 VDPVQKKEEPKKAQ---TKMSPKPDAKPMPKGSPTP-PGPRPTAGQTVPT-----PQQSP 896 Query: 61 GPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQL---------PQHPLTPAFMSPGKPE 111 P R S P +P +L L PG Sbjct: 897 KPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHS 956 Query: 112 HLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVP-KVFVPRPSQ 170 G+ PM+ P AP P SQ P PP +P K P+ Sbjct: 957 QSGPGA------PMKQAP-----APSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAA 1005 Query: 171 VSLKP------TEEAHKKERKPQKPGKYICQYCSRP--CAKPSVLQKHIRSHTGERPYPC 222 L+P T + + E+KP P K + P P+ L+K P P Sbjct: 1006 EKLEPKAEQAPTVKRTETEKKPP-PIKDSKSLTAEPQKAVLPTKLEKS--------PKPE 1056 Query: 223 GPCGFSFKTKSNLYKHRKSHAH---RIKAGLASGMGGEMYPHGLEMER--IPGEEFEEPT 277 C KT+ N+ + + K + + G PH E++ + + Sbjct: 1057 STCPLC-KTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAI 1115 Query: 278 EGESTDSEEETSATSGHPAELSPRPKQ---------PLLSSGLYSSGSHSSSHERCSLSQ 328 G+ D + A SG A P P + P + + E+ L + Sbjct: 1116 SGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEK 1175 Query: 329 SSTAQSLEDPPPFV-----------EPSSEHPLSHK---PEDTHTIKQKLALRLSERKKV 374 S+E PP V E L K PE+ I ++ +R E+K + Sbjct: 1176 VKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPL 1235 Query: 375 IDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKC-GRIGQRTAMLT 433 ++E+ K E +++ + E+Q + KS +I K GR+ +T Sbjct: 1236 LEEKKPTPEDKKLLPE----AKTSAPEEQ---KHDLLKSQVQIAEEKLEGRVAPKTVQ-- 1286 Query: 434 ATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSR 493 QP + E PS P S+P+ + TK I T++ D V+P + Sbjct: 1287 -EGKQPQTKM--EGLPSGTPQSLPKED--DKTTKTIKEQPQPPCTAKPDQVEPGK----E 1337 Query: 494 RSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTP 553 ++ E KS +S S++ K Q L + S S+ I T Sbjct: 1338 KTEKEDDKSD------TSSSQQPKSPQGLSDTGYSSDGI-------SSSLGEIPSLIPTD 1384 Query: 554 HHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDT 613 D +S S S + K + + L + S+ S K T Sbjct: 1385 EKDILKGLKKDSFSQESSPSSPSD--------LAKLESTVLSILEAQASTLADEKSEKKT 1436 Query: 614 ASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAK 673 +PK+ E T+ + L+ I E I ++ +++D + KK ++ +K Sbjct: 1437 QPHEVSPEQPKDQEKTQSLSETLEI--TISEEEIKESQEERKDTF---KKDSQQDIPSSK 1491 Query: 674 PISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFEST 733 S + EP+ + + + E +P+ +R++ S+G ++ Sbjct: 1492 D---HKEKSEFVDDITTRREPYDSV---EESSESENSPVPQRKRRTSVGSSSS-DEYKQE 1544 Query: 734 KSQFGSPGPSDAARNLPLE-STKSPAEPSK-------SVPSLEGPTGFQPRTPKPGSGS- 784 SQ GS D R +E S A S+ + + T Q + G G Sbjct: 1545 DSQ-GSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKI 1603 Query: 785 ESGKERRTTSKEISVI 800 +GK RR T K + I Sbjct: 1604 TAGKHRRLTRKSSTSI 1619 Score = 36.2 bits (82), Expect = 0.40 Identities = 57/223 (25%), Positives = 82/223 (36%), Gaps = 29/223 (13%) Query: 1217 FRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLS 1276 F PPS + + P LS+ +F ++ F + P S LP S++ L Sbjct: 2340 FDHPPSSV-IALPMKEQLSTTYFTSGET-FGQEKPA---SQLPSGSPSVSSLPAKPRPFF 2394 Query: 1277 PSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDT--------MVSLVVPVRVQTNMP 1328 S+ + PP PP P PP P P T L V V T P Sbjct: 2395 RSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454 Query: 1329 SYGSAMYTTLSQILVTQSQGSSATVALPKFEEP-PSKGTTVCGADVHEVGPGPSGLSEEQ 1387 + + TTL V +S G T P P K +++ V P PS + Sbjct: 2455 LFDAV--TTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPS-----K 2507 Query: 1388 SRAFPTPYL-RVPVTL-------PERKGTSLSSESILSLEGSS 1422 P P + ++P T P+ G SL+S L+L S+ Sbjct: 2508 PPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSA 2550 Score = 35.0 bits (79), Expect = 0.89 Identities = 86/360 (23%), Positives = 129/360 (35%), Gaps = 83/360 (23%) Query: 1107 DRPPLGP-TVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFST 1165 D PP +P E L + +T EKP P S L P + FF + Sbjct: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSL----PAKPRPFFRS 2396 Query: 1166 QAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLP 1225 ++ + + P PP PP PP P P PP P Sbjct: 2397 SSLD-ISAQPPPPPPPPP-----PPPPPPP------------------------PPPPPP 2426 Query: 1226 MPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDI 1285 +P PTS + LP + + + P + L T+L A + P T + Sbjct: 2427 LPPPTSPKPT---ILP-KKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT-- 2480 Query: 1286 RLPPVAPPASSSAPT----------SAPPLA-LPACPDTMVSLVVPVRVQTNMPSYGSAM 1334 PP PP SS P+ S PP+A P P + P + G ++ Sbjct: 2481 TAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPK--PTGLSL 2538 Query: 1335 YTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTP 1394 ++++ LVT SA LP P + P + S S++ Sbjct: 2539 TSSMTLNLVT-----SADYKLPSPTSP--------------LSPHSNKSSPRFSKSLTET 2579 Query: 1395 YLRVPVTLPERKGT---SLSSESILSLE-GSSSTAGGSKR----VLSPAGSLELTMETQQ 1446 Y V +TLP GT S +S++I S GS S S V+ P ++E+ + ++Q Sbjct: 2580 Y--VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQ 2637 Score = 34.7 bits (78), Expect = 1.2 Identities = 46/161 (28%), Positives = 60/161 (37%), Gaps = 26/161 (16%) Query: 2245 PTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPT 2304 P+ S S S P AK F SS L+ P P PP P P P P Sbjct: 2377 PSGSPSVSSLP-AKPRPFFRSSSLDISAQPP--------PPPPPPPPP-----PPPPPPP 2422 Query: 2305 HSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARF 2364 P PP T P+P + P+ + A +P +ATP D +++ A + Sbjct: 2423 PPPPLPPPTSPKP--------TILPKKKLTVA--SPVTTATPLFDAVTTLETTAVLRSNG 2472 Query: 2365 PARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPPNA 2405 TR + P PKPS H+PE PP A Sbjct: 2473 LPVTRICTTAP--PPVPPKPSSIPSGLVFTHRPEPSKPPIA 2511 Score = 34.3 bits (77), Expect = 1.5 Identities = 38/172 (22%), Positives = 64/172 (37%), Gaps = 19/172 (11%) Query: 1860 DEDEDEDEEESQDELSRPSSEAPPP----GPPHALRADSSPILGPQPPDAP----ASGTE 1911 + D D + S P + P G LRADS+ L P PP +P + + Sbjct: 3570 EADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISP 3629 Query: 1912 ATRGSSVSEA----ERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRR 1967 + G ++ A E+ S P + + PA + + + +S + Sbjct: 3630 LSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPA------SPKTAKMMQRSMSDPK 3683 Query: 1968 PWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPA-REPQASAPSPPGLHVDPG 2018 P SP+ + SR P T S S A ++ + + P+PP + G Sbjct: 3684 PLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTG 3735 Score = 33.1 bits (74), Expect = 3.4 Identities = 35/172 (20%), Positives = 56/172 (32%), Gaps = 14/172 (8%) Query: 1877 PSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSM 1936 P PPP PP L +SP P + T + + +A ++ + S + Sbjct: 2414 PPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGL 2473 Query: 1937 PGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQR 1996 P AP PV P+ PS + P K + PQ Sbjct: 2474 PVTRICTTAP--------------PPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQL 2519 Query: 1997 CSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPR 2048 + ++P P P GL + + + +L L P + +PR Sbjct: 2520 PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPR 2571 Score = 32.3 bits (72), Expect = 5.8 Identities = 65/285 (22%), Positives = 99/285 (34%), Gaps = 50/285 (17%) Query: 1329 SYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQS 1388 S S TT Q +V + QG + P ++ P K + GPG L ++ Sbjct: 182 SEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIP------KQQGPGRDPLQQD-- 233 Query: 1389 RAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQK 1448 GT S S + S G K + P T +T K Sbjct: 234 ------------------GTPKSISSQQPEKIKSQPPGTGKPIQGPT----QTPQTDHAK 271 Query: 1449 RVKEEEASKADEK-LELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPS 1507 + +AS+ K ++V+ SV + P K + G+ + S P Sbjct: 272 LPLQRDASRPQTKQADIVRGESVKPSLPS----PSKPPIQQPTPGKPPAQQPGHEKSQPG 327 Query: 1508 DTKEIPPLPHPALSHGTAPGSEALKEYPQPSG--KPHRRGLTPL------SVKKEDSKEQ 1559 K PP L+ A +K QP G KP + L P + ++ S EQ Sbjct: 328 PAK--PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ 385 Query: 1560 PDLPSLAPPSSLPLSETS----SRPAKSQEGTDSKKVLQFPSLHT 1600 P +LA P + + ++P Q GT K + Q P L + Sbjct: 386 PGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT-PKPLAQQPGLQS 429 >gi|189217876 sal-like 1 isoform b [Homo sapiens] Length = 1227 Score = 70.9 bits (172), Expect = 1e-11 Identities = 109/453 (24%), Positives = 166/453 (36%), Gaps = 84/453 (18%) Query: 38 PGSGTAATQESPAQEL---LAPQ--PFPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHI 92 P GT T +P L L+ Q G + L S +G +Q PP + P +S + Sbjct: 173 PSQGTLRTSANPLSTLSSHLSQQLAAAAGLAQSLASQSASISGVKQLPPIQLPQSSSGNT 232 Query: 93 -------SQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSG------SFVAPGLH 139 S + L A +P + + +P S S ++P + Sbjct: 233 IIPSNSGSSPNMNILAAAVTTPSSEKVASSAGASHVSNPAVSSSSSPAFAISSLLSPASN 292 Query: 140 PQSQLLPSHASI--IPPEDLPGVPKVFVPRPSQVSLKPTEEA--------HKKERKPQKP 189 P LLP AS + P LP + S +L ++ K + Sbjct: 293 P---LLPQQASANSVFPSPLPNIGTTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAF 349 Query: 190 GKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAG 249 K+ C++C++ S LQ H+RSHTGERP+ C CG F TK NL H + H Sbjct: 350 FKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK------ 403 Query: 250 LASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSS 309 E YPH ++M P E + ++G P +S P++P+ Sbjct: 404 -------EKYPH-IQMNPYPVPE-----------HLDNIPTSTGIPYGMSIPPEKPVT-- 442 Query: 310 GLYSSGSHSSSHERCSLSQSSTAQSLEDPP------PFV--EPSSEHPLSHK-PEDTHTI 360 S + L +T+ L PP PF+ E + P+SH ++ Sbjct: 443 --------SWLDTKPVLPTLTTSVGLPLPPTLPSLIPFIKTEEPAPIPISHSATSPPGSV 494 Query: 361 KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFG 420 K S + + L ++GST +SE + + T + S Sbjct: 495 KSDSGGPESATRNL----GGLPEEAEGSTLPPSGGKSEESGMVTNSVPTASSSVLSSPAA 550 Query: 421 KCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVP 453 CG G T T T PLLPL +E + P Sbjct: 551 DCGPAGSAT-----TFTNPLLPLMSEQFKAKFP 578 Score = 57.8 bits (138), Expect = 1e-07 Identities = 43/152 (28%), Positives = 64/152 (42%), Gaps = 15/152 (9%) Query: 95 LPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRP-GPSGSFVAPGLHPQSQLLPSHAS--- 150 L QH LT H + QL +P GP+ + + S L+ + + Sbjct: 947 LKQHMLT----------HQMRDLPSQLFEPSSNLGPNQNSAVIPANSLSSLIKTEVNGFV 996 Query: 151 IIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKH 210 + P+D P VP +S T + P ++ C C + + S LQ H Sbjct: 997 HVSPQDSKDTPTSHVPS-GPLSSSATSPVLLPALPRRTPKQHYCNTCGKTFSSSSALQIH 1055 Query: 211 IRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242 R+HTGE+P+ C CG +F TK NL H +H Sbjct: 1056 ERTHTGEKPFACTICGRAFTTKGNLKVHMGTH 1087 Score = 53.1 bits (126), Expect = 3e-06 Identities = 64/255 (25%), Positives = 98/255 (38%), Gaps = 20/255 (7%) Query: 1767 SMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM---KSKAHSKKCQETGVLEELEAEE 1823 S LK H RTHT RP+ CK C AF TKGNL H ++ + + ++ Sbjct: 622 SALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNA 681 Query: 1824 GTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPP 1883 + G + +S+ +SD+ S DE +D + DE E Sbjct: 682 VVLQQHIRMHMGGQIPNTPVPDSYSESMESDTGS-FDEKNFDDLDNFSDENMEDCPEGSI 740 Query: 1884 PGPPHALRA-----DSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPG 1938 P P + A SSP+ P + A+ + + AE+L AS S+ + S+ G Sbjct: 741 PDTPKSADASQDSLSSSPL--PLEMSSIAALENQMKMINAGLAEQLQASLKSVENGSIEG 798 Query: 1939 --LPWLGPAPLGSVE-KDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQ 1995 L + G +E + GS + S + SPS H + PQ Sbjct: 799 DVLTNDSSSVGGDMESQSAGSPAISESTSSMQALSPSNST------QEFHKSPSIEEKPQ 852 Query: 1996 RCSPAREPQASAPSP 2010 R P+ +P+P Sbjct: 853 RAVPSEFANGLSPTP 867 Score = 52.4 bits (124), Expect = 5e-06 Identities = 27/66 (40%), Positives = 33/66 (50%), Gaps = 5/66 (7%) Query: 177 EEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLY 236 E KK P + C C R + S L+ H R+HTGERP+ C CG +F TK NL Sbjct: 599 ENIDKKATDPNE-----CIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLK 653 Query: 237 KHRKSH 242 H H Sbjct: 654 THYSVH 659 Score = 51.6 bits (122), Expect = 9e-06 Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 3/56 (5%) Query: 1749 RGRGKY---VCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM 1801 R RGK+ C+ CG S L H R+HT RP++C C+ F TKGNL +HM Sbjct: 896 RDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHM 951 Score = 49.7 bits (117), Expect = 3e-05 Identities = 23/52 (44%), Positives = 27/52 (51%) Query: 194 CQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHR 245 C C + A S L H RSHT ERP+ C C F TK NL +H +H R Sbjct: 906 CDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHMLTHQMR 957 Score = 48.5 bits (114), Expect = 8e-05 Identities = 22/49 (44%), Positives = 27/49 (55%) Query: 1753 KYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM 1801 ++ C CG S L+ H RTHT +P+ C C AF TKGNL HM Sbjct: 1036 QHYCNTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHM 1084 Score = 47.0 bits (110), Expect = 2e-04 Identities = 64/263 (24%), Positives = 101/263 (38%), Gaps = 39/263 (14%) Query: 1556 SKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLH---TTTNVSWCYLNYI 1612 + + DLP+ + PS L TS+ P + S+++ L + + S + + Sbjct: 161 ASQNADLPTSSSPSQGTL-RTSANPLSTLSSHLSQQLAAAAGLAQSLASQSASISGVKQL 219 Query: 1613 KPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEA 1672 P + + +++ I + + P ++ AA S +KV+ A A H Sbjct: 220 PPIQLPQSSSGNTI-----IPSNSGSSPNMNILAAAVTTPSSEKVASS----AGASH--V 268 Query: 1673 GRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEE-------RRGEPEED-----AP 1720 SSS P + SL+SP L + G ED A Sbjct: 269 SNPAVSSSSSPAFA---ISSLLSPASNPLLPQQASANSVFPSPLPNIGTTAEDLNSLSAL 325 Query: 1721 ASQR-GEPARIKIFEGGYKSNEEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDV 1779 A QR +P + FE S+E + K+ C C S L+ H+R+HT Sbjct: 326 AQQRKSKPPNVTAFEAKSTSDEAFF--------KHKCRFCAKVFGSDSALQIHLRSHTGE 377 Query: 1780 RPYVCKHCHFAFKTKGNLTKHMK 1802 RP+ C C F TKGNL H + Sbjct: 378 RPFKCNICGNRFSTKGNLKVHFQ 400 Score = 32.3 bits (72), Expect = 5.8 Identities = 39/152 (25%), Positives = 57/152 (37%), Gaps = 11/152 (7%) Query: 1229 PTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLP 1288 PTSS+ S G + + + SHL Q + A LA A S S S +LP Sbjct: 168 PTSSSPSQGTLRTSANPLST-----LSSHLSQQLAAAAGLAQSLA--SQSASISGVKQLP 220 Query: 1289 PVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQG 1348 P+ P SSS T P + + +++ V + S A + + + S Sbjct: 221 PIQLPQSSSGNTIIPSNSGSSPNMNILAAAVTTPSSEKVASSAGASHVSNPAV----SSS 276 Query: 1349 SSATVALPKFEEPPSKGTTVCGADVHEVGPGP 1380 SS A+ P S A + V P P Sbjct: 277 SSPAFAISSLLSPASNPLLPQQASANSVFPSP 308 >gi|118442837 sal-like 1 isoform a [Homo sapiens] Length = 1324 Score = 70.9 bits (172), Expect = 1e-11 Identities = 109/453 (24%), Positives = 166/453 (36%), Gaps = 84/453 (18%) Query: 38 PGSGTAATQESPAQEL---LAPQ--PFPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHI 92 P GT T +P L L+ Q G + L S +G +Q PP + P +S + Sbjct: 270 PSQGTLRTSANPLSTLSSHLSQQLAAAAGLAQSLASQSASISGVKQLPPIQLPQSSSGNT 329 Query: 93 -------SQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSG------SFVAPGLH 139 S + L A +P + + +P S S ++P + Sbjct: 330 IIPSNSGSSPNMNILAAAVTTPSSEKVASSAGASHVSNPAVSSSSSPAFAISSLLSPASN 389 Query: 140 PQSQLLPSHASI--IPPEDLPGVPKVFVPRPSQVSLKPTEEA--------HKKERKPQKP 189 P LLP AS + P LP + S +L ++ K + Sbjct: 390 P---LLPQQASANSVFPSPLPNIGTTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAF 446 Query: 190 GKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAG 249 K+ C++C++ S LQ H+RSHTGERP+ C CG F TK NL H + H Sbjct: 447 FKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK------ 500 Query: 250 LASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSS 309 E YPH ++M P E + ++G P +S P++P+ Sbjct: 501 -------EKYPH-IQMNPYPVPE-----------HLDNIPTSTGIPYGMSIPPEKPVT-- 539 Query: 310 GLYSSGSHSSSHERCSLSQSSTAQSLEDPP------PFV--EPSSEHPLSHK-PEDTHTI 360 S + L +T+ L PP PF+ E + P+SH ++ Sbjct: 540 --------SWLDTKPVLPTLTTSVGLPLPPTLPSLIPFIKTEEPAPIPISHSATSPPGSV 591 Query: 361 KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFG 420 K S + + L ++GST +SE + + T + S Sbjct: 592 KSDSGGPESATRNL----GGLPEEAEGSTLPPSGGKSEESGMVTNSVPTASSSVLSSPAA 647 Query: 421 KCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVP 453 CG G T T T PLLPL +E + P Sbjct: 648 DCGPAGSAT-----TFTNPLLPLMSEQFKAKFP 675 Score = 57.8 bits (138), Expect = 1e-07 Identities = 43/152 (28%), Positives = 64/152 (42%), Gaps = 15/152 (9%) Query: 95 LPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRP-GPSGSFVAPGLHPQSQLLPSHAS--- 150 L QH LT H + QL +P GP+ + + S L+ + + Sbjct: 1044 LKQHMLT----------HQMRDLPSQLFEPSSNLGPNQNSAVIPANSLSSLIKTEVNGFV 1093 Query: 151 IIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKH 210 + P+D P VP +S T + P ++ C C + + S LQ H Sbjct: 1094 HVSPQDSKDTPTSHVPS-GPLSSSATSPVLLPALPRRTPKQHYCNTCGKTFSSSSALQIH 1152 Query: 211 IRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242 R+HTGE+P+ C CG +F TK NL H +H Sbjct: 1153 ERTHTGEKPFACTICGRAFTTKGNLKVHMGTH 1184 Score = 53.1 bits (126), Expect = 3e-06 Identities = 64/255 (25%), Positives = 98/255 (38%), Gaps = 20/255 (7%) Query: 1767 SMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM---KSKAHSKKCQETGVLEELEAEE 1823 S LK H RTHT RP+ CK C AF TKGNL H ++ + + ++ Sbjct: 719 SALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNA 778 Query: 1824 GTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPP 1883 + G + +S+ +SD+ S DE +D + DE E Sbjct: 779 VVLQQHIRMHMGGQIPNTPVPDSYSESMESDTGS-FDEKNFDDLDNFSDENMEDCPEGSI 837 Query: 1884 PGPPHALRA-----DSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPG 1938 P P + A SSP+ P + A+ + + AE+L AS S+ + S+ G Sbjct: 838 PDTPKSADASQDSLSSSPL--PLEMSSIAALENQMKMINAGLAEQLQASLKSVENGSIEG 895 Query: 1939 --LPWLGPAPLGSVE-KDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQ 1995 L + G +E + GS + S + SPS H + PQ Sbjct: 896 DVLTNDSSSVGGDMESQSAGSPAISESTSSMQALSPSNST------QEFHKSPSIEEKPQ 949 Query: 1996 RCSPAREPQASAPSP 2010 R P+ +P+P Sbjct: 950 RAVPSEFANGLSPTP 964 Score = 52.4 bits (124), Expect = 5e-06 Identities = 27/66 (40%), Positives = 33/66 (50%), Gaps = 5/66 (7%) Query: 177 EEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLY 236 E KK P + C C R + S L+ H R+HTGERP+ C CG +F TK NL Sbjct: 696 ENIDKKATDPNE-----CIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLK 750 Query: 237 KHRKSH 242 H H Sbjct: 751 THYSVH 756 Score = 51.6 bits (122), Expect = 9e-06 Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 3/56 (5%) Query: 1749 RGRGKY---VCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM 1801 R RGK+ C+ CG S L H R+HT RP++C C+ F TKGNL +HM Sbjct: 993 RDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHM 1048 Score = 49.7 bits (117), Expect = 3e-05 Identities = 23/52 (44%), Positives = 27/52 (51%) Query: 194 CQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHR 245 C C + A S L H RSHT ERP+ C C F TK NL +H +H R Sbjct: 1003 CDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHMLTHQMR 1054 Score = 48.5 bits (114), Expect = 8e-05 Identities = 22/49 (44%), Positives = 27/49 (55%) Query: 1753 KYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM 1801 ++ C CG S L+ H RTHT +P+ C C AF TKGNL HM Sbjct: 1133 QHYCNTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHM 1181 Score = 47.0 bits (110), Expect = 2e-04 Identities = 64/263 (24%), Positives = 101/263 (38%), Gaps = 39/263 (14%) Query: 1556 SKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLH---TTTNVSWCYLNYI 1612 + + DLP+ + PS L TS+ P + S+++ L + + S + + Sbjct: 258 ASQNADLPTSSSPSQGTL-RTSANPLSTLSSHLSQQLAAAAGLAQSLASQSASISGVKQL 316 Query: 1613 KPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEA 1672 P + + +++ I + + P ++ AA S +KV+ A A H Sbjct: 317 PPIQLPQSSSGNTI-----IPSNSGSSPNMNILAAAVTTPSSEKVASS----AGASH--V 365 Query: 1673 GRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEE-------RRGEPEED-----AP 1720 SSS P + SL+SP L + G ED A Sbjct: 366 SNPAVSSSSSPAFA---ISSLLSPASNPLLPQQASANSVFPSPLPNIGTTAEDLNSLSAL 422 Query: 1721 ASQR-GEPARIKIFEGGYKSNEEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDV 1779 A QR +P + FE S+E + K+ C C S L+ H+R+HT Sbjct: 423 AQQRKSKPPNVTAFEAKSTSDEAFF--------KHKCRFCAKVFGSDSALQIHLRSHTGE 474 Query: 1780 RPYVCKHCHFAFKTKGNLTKHMK 1802 RP+ C C F TKGNL H + Sbjct: 475 RPFKCNICGNRFSTKGNLKVHFQ 497 Score = 32.3 bits (72), Expect = 5.8 Identities = 39/152 (25%), Positives = 57/152 (37%), Gaps = 11/152 (7%) Query: 1229 PTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLP 1288 PTSS+ S G + + + SHL Q + A LA A S S S +LP Sbjct: 265 PTSSSPSQGTLRTSANPLST-----LSSHLSQQLAAAAGLAQSLA--SQSASISGVKQLP 317 Query: 1289 PVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQG 1348 P+ P SSS T P + + +++ V + S A + + + S Sbjct: 318 PIQLPQSSSGNTIIPSNSGSSPNMNILAAAVTTPSSEKVASSAGASHVSNPAV----SSS 373 Query: 1349 SSATVALPKFEEPPSKGTTVCGADVHEVGPGP 1380 SS A+ P S A + V P P Sbjct: 374 SSPAFAISSLLSPASNPLLPQQASANSVFPSP 405 >gi|40807465 zinc finger protein 341 [Homo sapiens] Length = 847 Score = 70.9 bits (172), Expect = 1e-11 Identities = 82/356 (23%), Positives = 123/356 (34%), Gaps = 82/356 (23%) Query: 3 PEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGP 62 P Q ++ G P + G + S++ P GSGT Q L QP+ Sbjct: 193 PPQPPPPPPQSLGPPGRPNPGGNGVVEVYSAAAPLAGSGTVEIQ------ALGMQPY--- 243 Query: 63 SSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLV 122 PP+E + P +P TP SPGK Sbjct: 244 ---------------------PPLEVPNQCVEPPVYP-TPTVYSPGKQ------------ 269 Query: 123 DPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKK 182 F G +P + + + + D P K R ++ + KP Sbjct: 270 ---------GFKPKGPNPAAPMTSATGGTVATFDSPATLKT---RRAKAAGKP------- 310 Query: 183 ERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242 K K C YC + K LQ+HIRSHTGE+P+ C CG +F KSN+ KH ++H Sbjct: 311 -----KAQKLKCSYCDKSFTKNFDLQQHIRSHTGEKPFQCIACGRAFAQKSNVKKHMQTH 365 Query: 243 AHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRP 302 K GG + + + ++ + + E+E S G P +P+P Sbjct: 366 ----KVWPPGHSGGTVSRNSVTVQVMALNPSRQ---------EDEESTGLGQPLPGAPQP 412 Query: 303 KQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTH 358 + LS+ G S + + S Q H HK E + Sbjct: 413 Q--ALSTAGEEEGDKPESKQVVLIDSSYLCQFCPSKFSTYFQLKSHMTQHKNEQVY 466 Score = 52.0 bits (123), Expect = 7e-06 Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 21/164 (12%) Query: 191 KYICQY-----CSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHR 245 KY C + CS+ +P L+ HI SH+G + + C C SF +++L +H+++H Sbjct: 642 KYKCPFSTHTGCSKEFNRPDKLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAHTGN 701 Query: 246 IK---AGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRP 302 K AG A G Y P ++ + T S SG L+P P Sbjct: 702 YKFRCAGCAKGFSRHKYLKDHRCRLGPQKDKDLQTRRPPQRRAAPRSCGSGGRKVLTPLP 761 Query: 303 KQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSS 346 PL L +G+ +++ PPF EP + Sbjct: 762 -DPLGLEELKDTGA------------GLVPEAVPGKPPFAEPDA 792 Score = 45.1 bits (105), Expect = 9e-04 Identities = 18/53 (33%), Positives = 27/53 (50%) Query: 190 GKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242 G++ CQ C + + L+ H H+GE+PY C C +F K L +H H Sbjct: 585 GRFKCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIH 637 Score = 42.7 bits (99), Expect = 0.004 Identities = 20/51 (39%), Positives = 28/51 (54%) Query: 1753 KYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKS 1803 K C C K L++HIR+HT +P+ C C AF K N+ KHM++ Sbjct: 314 KLKCSYCDKSFTKNFDLQQHIRSHTGEKPFQCIACGRAFAQKSNVKKHMQT 364 Score = 42.7 bits (99), Expect = 0.004 Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 4/92 (4%) Query: 159 GVPKVFVPRPSQVSLKPTEEAHKKERKPQK--PGKYICQYCSRPCAKPSVLQKHIRSHTG 216 G P P+P +S EE K E K Y+CQ+C + L+ H+ H Sbjct: 403 GQPLPGAPQPQALSTAGEEEGDKPESKQVVLIDSSYLCQFCPSKFSTYFQLKSHMTQHKN 462 Query: 217 ERPYPC--GPCGFSFKTKSNLYKHRKSHAHRI 246 E+ Y C C +F +H KSH + Sbjct: 463 EQVYKCVVKSCAQTFPKLDTFLEHIKSHQEEL 494 Score = 41.2 bits (95), Expect = 0.012 Identities = 22/76 (28%), Positives = 38/76 (50%) Query: 168 PSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGF 227 PS+ S ++H + K ++ K + + C++ K +HI+SH E Y C CG Sbjct: 444 PSKFSTYFQLKSHMTQHKNEQVYKCVVKSCAQTFPKLDTFLEHIKSHQEELSYRCHLCGK 503 Query: 228 SFKTKSNLYKHRKSHA 243 F + +L H+ SH+ Sbjct: 504 DFPSLYDLGVHQYSHS 519 Score = 41.2 bits (95), Expect = 0.012 Identities = 17/50 (34%), Positives = 25/50 (50%) Query: 1752 GKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM 1801 G++ C+ C ++ LK H H+ +PY C C AF K L +HM Sbjct: 585 GRFKCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHM 634 Score = 33.5 bits (75), Expect = 2.6 Identities = 38/152 (25%), Positives = 59/152 (38%), Gaps = 19/152 (12%) Query: 1654 KQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEERRG 1713 K V K T P +G V +S V + +L +P Q+D +E G Sbjct: 355 KSNVKKHMQTHKVWPPGHSGGTVSRNS-----VTVQVMAL-NPSRQED-----EESTGLG 403 Query: 1714 EPEEDAPASQRGEPARIKIFEGGYKSNEEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHI 1773 +P AP Q A + EG +++ V + Y+C+ C + LK H+ Sbjct: 404 QPLPGAPQPQALSTAGEE--EGDKPESKQVVLIDS----SYLCQFCPSKFSTYFQLKSHM 457 Query: 1774 RTHTDVRPYVC--KHCHFAFKTKGNLTKHMKS 1803 H + + Y C K C F +H+KS Sbjct: 458 TQHKNEQVYKCVVKSCAQTFPKLDTFLEHIKS 489 Score = 32.7 bits (73), Expect = 4.4 Identities = 37/133 (27%), Positives = 49/133 (36%), Gaps = 10/133 (7%) Query: 748 NLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFE 807 N P +T S A S PS PT Q + P P + S S I + + Sbjct: 79 NAPALATVSLATNSIYPPSA-APTAVQ-QAPTPANRQISTYITVPPSPLIQTLVQGNILV 136 Query: 808 KSDSLEQP-SGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDR 866 D L S D+P+ Q PPP + HS+ L + P P P Sbjct: 137 SDDVLMSAMSAFTSLDQPMPQ--GPPPVQSSLNMHSVPSYLTQPPPPPPPP-----PPLP 189 Query: 867 PDTEPEPPPKEPE 879 P P+PPP P+ Sbjct: 190 PPPPPQPPPPPPQ 202 Score = 32.0 bits (71), Expect = 7.5 Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 4/60 (6%) Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK--KCQ 1811 Y C +C + P L+ H++T T P C HC F + L +H+ + KCQ Sbjct: 533 YKCVKCVNKYSTPEALEHHLQTATHNFP--CPHCQKVFPCERYLRRHLPTHGSGGRFKCQ 590 >gi|221139761 zinc finger protein 853 [Homo sapiens] Length = 659 Score = 69.3 bits (168), Expect = 4e-11 Identities = 29/64 (45%), Positives = 42/64 (65%), Gaps = 2/64 (3%) Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239 H++ +KP Y C YC++ ++ S L +H R+HTGERPY CG CG F SNL +HR Sbjct: 531 HQRIHTGEKP--YACSYCAKRFSESSALVQHQRTHTGERPYACGDCGKRFSVSSNLLRHR 588 Query: 240 KSHA 243 ++H+ Sbjct: 589 RTHS 592 Score = 60.8 bits (146), Expect = 2e-08 Identities = 51/179 (28%), Positives = 81/179 (45%), Gaps = 20/179 (11%) Query: 68 EGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRP 127 E Q++ QQ+ + P+E ++ Q LTP +PE LE LV Sbjct: 373 EQQQQQLEQQEVQLELTPVELGAQQQEV-QLELTPV-----QPELQLE-----LVPAAGG 421 Query: 128 GPSGSFVAPG---LHPQSQLLPSHASIIPPEDLPGVPKVFVPRPS-QVSLKPTEEAHKKE 183 G + AP + P ++ ++P P V V +P P+ +L P A ++ Sbjct: 422 GGAAVPGAPAAVVVAPPGYVVVQELMVLPAVAAPAV--VAIPGPAGSAALTP---ARQRR 476 Query: 184 RKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242 R+ + IC C + ++ + L +H +HTGERP+ CG CG F SNL H++ H Sbjct: 477 RRRARDRPTICGECGKGFSRSTDLVRHQATHTGERPHRCGECGKGFSQHSNLVTHQRIH 535 Score = 49.3 bits (116), Expect = 5e-05 Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 2/67 (2%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKK 1809 G Y C C R + S L +H RTHT RPY C C F NL +H ++ + + Sbjct: 537 GEKPYACSYCAKRFSESSALVQHQRTHTGERPYACGDCGKRFSVSSNLLRHRRTHSGERP 596 Query: 1810 --CQETG 1814 C++ G Sbjct: 597 YVCEDCG 603 Score = 49.3 bits (116), Expect = 5e-05 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 7/77 (9%) Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKH- 238 H++ ++P Y C C + + S L +H R+H+GERPY C CG F+ K + +H Sbjct: 559 HQRTHTGERP--YACGDCGKRFSVSSNLLRHRRTHSGERPYVCEDCGERFRHKVQIRRHE 616 Query: 239 RKSHAHRIKAGLASGMG 255 R+ H AG + G+G Sbjct: 617 RQLHG----AGRSRGLG 629 Score = 48.9 bits (115), Expect = 6e-05 Identities = 23/67 (34%), Positives = 35/67 (52%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKK 1809 G Y C +CG R S L +H RTH+ RPYVC+ C F+ K + +H + + + Sbjct: 565 GERPYACGDCGKRFSVSSNLLRHRRTHSGERPYVCEDCGERFRHKVQIRRHERQLHGAGR 624 Query: 1810 CQETGVL 1816 + G+L Sbjct: 625 SRGLGLL 631 Score = 45.1 bits (105), Expect = 9e-04 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 2/63 (3%) Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239 H+ ++P + C C + ++ S L H R HTGE+PY C C F S L +H+ Sbjct: 503 HQATHTGERPHR--CGECGKGFSQHSNLVTHQRIHTGEKPYACSYCAKRFSESSALVQHQ 560 Query: 240 KSH 242 ++H Sbjct: 561 RTH 563 Score = 41.6 bits (96), Expect = 0.010 Identities = 31/118 (26%), Positives = 49/118 (41%), Gaps = 9/118 (7%) Query: 1688 VHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSNEEYVYVR 1747 V P++V+ G A + +RR D P GE + G+ + + V + Sbjct: 452 VAAPAVVAIPGPAGSAALTPARQRRRRRARDRPTIC-GECGK------GFSRSTDLVRHQ 504 Query: 1748 GRGRGK--YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKS 1803 G+ + C ECG + S L H R HT +PY C +C F L +H ++ Sbjct: 505 ATHTGERPHRCGECGKGFSQHSNLVTHQRIHTGEKPYACSYCAKRFSESSALVQHQRT 562 >gi|193082982 zinc finger protein 837 isoform 1 [Homo sapiens] Length = 531 Score = 68.9 bits (167), Expect = 6e-11 Identities = 30/66 (45%), Positives = 42/66 (63%), Gaps = 2/66 (3%) Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239 H++ +KP YIC+ C + + L +H+R+HTGERPY CG CG +F +SNL +HR Sbjct: 465 HERLHSGEKP--YICRDCGKAFVRNCSLVRHLRTHTGERPYACGDCGRAFSQRSNLNEHR 522 Query: 240 KSHAHR 245 K H R Sbjct: 523 KRHGGR 528 Score = 61.2 bits (147), Expect = 1e-08 Identities = 62/253 (24%), Positives = 88/253 (34%), Gaps = 49/253 (19%) Query: 36 PYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPK------------- 82 P PG+ +A +E P P V+ EG Q + G + P + Sbjct: 74 PGPGTRHSAGTRPLVREPCGPTSSQNPELVIPEGLQAREGPCRSPARGGDCSRNSCLAWH 133 Query: 83 -------RPPI---------------EASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQ 120 PP+ VH P P T A P P+ G Sbjct: 134 RGAPAGETPPVCDPCPERIQNHPRTQLCEVHTDCWPCQPGTGAPTCPRTPKPTSRGRNPL 193 Query: 121 LVDPMRPGPSGSFVAPGLH-PQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPT--- 176 + P +F L PQ +L + P K F P Q + K Sbjct: 194 VEQPRACACGEAFAWRALRIPQERLQATEE----PRPCARCGKRFRPNQQQQAGKSPPVC 249 Query: 177 ----EEAHKKERKPQKPGK--YICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFK 230 + + + P P + Y C C + + S L +H R HTGERPY C CG +F Sbjct: 250 PECGQTSRPRPIVPDPPAQRLYACDECGKAFTRTSSLLQHQRIHTGERPYECAECGKAFV 309 Query: 231 TKSNLYKHRKSHA 243 S LY+H+K+H+ Sbjct: 310 RCSGLYRHQKTHS 322 Score = 53.5 bits (127), Expect = 2e-06 Identities = 25/64 (39%), Positives = 35/64 (54%), Gaps = 2/64 (3%) Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239 H++ KP Y C C + S L +H R+HTGERPY C CG +F+ S L +H Sbjct: 409 HQRTHSSAKP--YACPLCEKAFKGRSGLVQHQRAHTGERPYGCSECGKTFRGCSELRQHE 466 Query: 240 KSHA 243 + H+ Sbjct: 467 RLHS 470 Score = 53.1 bits (126), Expect = 3e-06 Identities = 22/53 (41%), Positives = 29/53 (54%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMK 1802 G Y+C +CG + L +H+RTHT RPY C C AF + NL +H K Sbjct: 471 GEKPYICRDCGKAFVRNCSLVRHLRTHTGERPYACGDCGRAFSQRSNLNEHRK 523 Score = 52.8 bits (125), Expect = 4e-06 Identities = 24/57 (42%), Positives = 36/57 (63%), Gaps = 2/57 (3%) Query: 187 QKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHA 243 +KP Y C C++ S L +H R HTGE+PY C CG +F +SNL +H+++H+ Sbjct: 360 EKP--YECADCAKAFGLFSHLVEHRRVHTGEKPYACPECGKAFNQRSNLSRHQRTHS 414 Score = 52.8 bits (125), Expect = 4e-06 Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 2/67 (2%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKK 1809 G Y C ECG + S L +H RTH+ +PY C C AFK + L +H ++ + Sbjct: 387 GEKPYACPECGKAFNQRSNLSRHQRTHSSAKPYACPLCEKAFKGRSGLVQHQRAHTGERP 446 Query: 1810 --CQETG 1814 C E G Sbjct: 447 YGCSECG 453 Score = 48.5 bits (114), Expect = 8e-05 Identities = 21/63 (33%), Positives = 36/63 (57%), Gaps = 2/63 (3%) Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239 H++ +KP Y C C + + S L +H R+H+ +PY C C +FK +S L +H+ Sbjct: 381 HRRVHTGEKP--YACPECGKAFNQRSNLSRHQRTHSSAKPYACPLCEKAFKGRSGLVQHQ 438 Query: 240 KSH 242 ++H Sbjct: 439 RAH 441 Score = 47.8 bits (112), Expect = 1e-04 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 2/64 (3%) Query: 1747 RGRGRGK--YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSK 1804 RG G G+ Y C +C S L +H R HT +PY C C AF + NL++H ++ Sbjct: 354 RGSGAGEKPYECADCAKAFGLFSHLVEHRRVHTGEKPYACPECGKAFNQRSNLSRHQRTH 413 Query: 1805 AHSK 1808 + +K Sbjct: 414 SSAK 417 Score = 47.0 bits (110), Expect = 2e-04 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 2/63 (3%) Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239 H++ ++P Y C C + S L++H R H+GE+PY C CG +F +L +H Sbjct: 437 HQRAHTGERP--YGCSECGKTFRGCSELRQHERLHSGEKPYICRDCGKAFVRNCSLVRHL 494 Query: 240 KSH 242 ++H Sbjct: 495 RTH 497 Score = 46.6 bits (109), Expect = 3e-04 Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 2/61 (3%) Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQET 1813 Y C+ECG + S L +H R HT RPY C C AF L +H K+ HS + Sbjct: 271 YACDECGKAFTRTSSLLQHQRIHTGERPYECAECGKAFVRCSGLYRHQKT--HSAERHRR 328 Query: 1814 G 1814 G Sbjct: 329 G 329 Score = 46.2 bits (108), Expect = 4e-04 Identities = 19/54 (35%), Positives = 31/54 (57%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKS 1803 G Y C ECG + S L++H R H+ +PY+C+ C AF +L +H+++ Sbjct: 443 GERPYGCSECGKTFRGCSELRQHERLHSGEKPYICRDCGKAFVRNCSLVRHLRT 496 Score = 37.7 bits (86), Expect = 0.14 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 2/63 (3%) Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKK--CQ 1811 Y C C K S L +H R HT RPY C C F+ L +H + + K C+ Sbjct: 419 YACPLCEKAFKGRSGLVQHQRAHTGERPYGCSECGKTFRGCSELRQHERLHSGEKPYICR 478 Query: 1812 ETG 1814 + G Sbjct: 479 DCG 481 Score = 36.2 bits (82), Expect = 0.40 Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 1/81 (1%) Query: 162 KVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYP 221 K FV + T A + R P + C PC S S GE+PY Sbjct: 306 KAFVRCSGLYRHQKTHSAERHRRGPVLARRAFRLGCP-PCGDYSERSPRRGSGAGEKPYE 364 Query: 222 CGPCGFSFKTKSNLYKHRKSH 242 C C +F S+L +HR+ H Sbjct: 365 CADCAKAFGLFSHLVEHRRVH 385 >gi|193082980 zinc finger protein 837 isoform 2 [Homo sapiens] Length = 531 Score = 68.9 bits (167), Expect = 6e-11 Identities = 30/66 (45%), Positives = 42/66 (63%), Gaps = 2/66 (3%) Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239 H++ +KP YIC+ C + + L +H+R+HTGERPY CG CG +F +SNL +HR Sbjct: 465 HERLHSGEKP--YICRDCGKAFVRNCSLVRHLRTHTGERPYACGDCGRAFSQRSNLNEHR 522 Query: 240 KSHAHR 245 K H R Sbjct: 523 KRHGGR 528 Score = 61.2 bits (147), Expect = 1e-08 Identities = 62/253 (24%), Positives = 88/253 (34%), Gaps = 49/253 (19%) Query: 36 PYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPK------------- 82 P PG+ +A +E P P V+ EG Q + G + P + Sbjct: 74 PGPGTRHSAGTRPLVREPCGPTSSQNPELVIPEGLQAREGPCRSPARGGDCSRNSCLAWH 133 Query: 83 -------RPPI---------------EASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQ 120 PP+ VH P P T A P P+ G Sbjct: 134 RGAPAGETPPVCDPCPERIQNHPRTQLCEVHTDCWPCQPGTGAPTCPRTPKPTSRGRNPL 193 Query: 121 LVDPMRPGPSGSFVAPGLH-PQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPT--- 176 + P +F L PQ +L + P K F P Q + K Sbjct: 194 VEQPRACACGEAFAWRALRIPQERLQATEE----PRPCARCGKRFRPNQQQQAGKSPPVC 249 Query: 177 ----EEAHKKERKPQKPGK--YICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFK 230 + + + P P + Y C C + + S L +H R HTGERPY C CG +F Sbjct: 250 PECGQTSRPRPIVPDPPAQRLYACDECGKAFTRTSSLLQHQRIHTGERPYECAECGKAFV 309 Query: 231 TKSNLYKHRKSHA 243 S LY+H+K+H+ Sbjct: 310 RCSGLYRHQKTHS 322 Score = 53.5 bits (127), Expect = 2e-06 Identities = 25/64 (39%), Positives = 35/64 (54%), Gaps = 2/64 (3%) Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239 H++ KP Y C C + S L +H R+HTGERPY C CG +F+ S L +H Sbjct: 409 HQRTHSSAKP--YACPLCEKAFKGRSGLVQHQRAHTGERPYGCSECGKTFRGCSELRQHE 466 Query: 240 KSHA 243 + H+ Sbjct: 467 RLHS 470 Score = 53.1 bits (126), Expect = 3e-06 Identities = 22/53 (41%), Positives = 29/53 (54%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMK 1802 G Y+C +CG + L +H+RTHT RPY C C AF + NL +H K Sbjct: 471 GEKPYICRDCGKAFVRNCSLVRHLRTHTGERPYACGDCGRAFSQRSNLNEHRK 523 Score = 52.8 bits (125), Expect = 4e-06 Identities = 24/57 (42%), Positives = 36/57 (63%), Gaps = 2/57 (3%) Query: 187 QKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHA 243 +KP Y C C++ S L +H R HTGE+PY C CG +F +SNL +H+++H+ Sbjct: 360 EKP--YECADCAKAFGLFSHLVEHRRVHTGEKPYACPECGKAFNQRSNLSRHQRTHS 414 Score = 52.8 bits (125), Expect = 4e-06 Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 2/67 (2%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKK 1809 G Y C ECG + S L +H RTH+ +PY C C AFK + L +H ++ + Sbjct: 387 GEKPYACPECGKAFNQRSNLSRHQRTHSSAKPYACPLCEKAFKGRSGLVQHQRAHTGERP 446 Query: 1810 --CQETG 1814 C E G Sbjct: 447 YGCSECG 453 Score = 48.5 bits (114), Expect = 8e-05 Identities = 21/63 (33%), Positives = 36/63 (57%), Gaps = 2/63 (3%) Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239 H++ +KP Y C C + + S L +H R+H+ +PY C C +FK +S L +H+ Sbjct: 381 HRRVHTGEKP--YACPECGKAFNQRSNLSRHQRTHSSAKPYACPLCEKAFKGRSGLVQHQ 438 Query: 240 KSH 242 ++H Sbjct: 439 RAH 441 Score = 47.8 bits (112), Expect = 1e-04 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 2/64 (3%) Query: 1747 RGRGRGK--YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSK 1804 RG G G+ Y C +C S L +H R HT +PY C C AF + NL++H ++ Sbjct: 354 RGSGAGEKPYECADCAKAFGLFSHLVEHRRVHTGEKPYACPECGKAFNQRSNLSRHQRTH 413 Query: 1805 AHSK 1808 + +K Sbjct: 414 SSAK 417 Score = 47.0 bits (110), Expect = 2e-04 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 2/63 (3%) Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239 H++ ++P Y C C + S L++H R H+GE+PY C CG +F +L +H Sbjct: 437 HQRAHTGERP--YGCSECGKTFRGCSELRQHERLHSGEKPYICRDCGKAFVRNCSLVRHL 494 Query: 240 KSH 242 ++H Sbjct: 495 RTH 497 Score = 46.6 bits (109), Expect = 3e-04 Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 2/61 (3%) Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQET 1813 Y C+ECG + S L +H R HT RPY C C AF L +H K+ HS + Sbjct: 271 YACDECGKAFTRTSSLLQHQRIHTGERPYECAECGKAFVRCSGLYRHQKT--HSAERHRR 328 Query: 1814 G 1814 G Sbjct: 329 G 329 Score = 46.2 bits (108), Expect = 4e-04 Identities = 19/54 (35%), Positives = 31/54 (57%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKS 1803 G Y C ECG + S L++H R H+ +PY+C+ C AF +L +H+++ Sbjct: 443 GERPYGCSECGKTFRGCSELRQHERLHSGEKPYICRDCGKAFVRNCSLVRHLRT 496 Score = 37.7 bits (86), Expect = 0.14 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 2/63 (3%) Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKK--CQ 1811 Y C C K S L +H R HT RPY C C F+ L +H + + K C+ Sbjct: 419 YACPLCEKAFKGRSGLVQHQRAHTGERPYGCSECGKTFRGCSELRQHERLHSGEKPYICR 478 Query: 1812 ETG 1814 + G Sbjct: 479 DCG 481 Score = 36.2 bits (82), Expect = 0.40 Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 1/81 (1%) Query: 162 KVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYP 221 K FV + T A + R P + C PC S S GE+PY Sbjct: 306 KAFVRCSGLYRHQKTHSAERHRRGPVLARRAFRLGCP-PCGDYSERSPRRGSGAGEKPYE 364 Query: 222 CGPCGFSFKTKSNLYKHRKSH 242 C C +F S+L +HR+ H Sbjct: 365 CADCAKAFGLFSHLVEHRRVH 385 >gi|4508009 zinc finger protein 177 [Homo sapiens] Length = 321 Score = 68.6 bits (166), Expect = 7e-11 Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%) Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239 HK+ +KP Y C+ C + PS LQKH+R+HTGE+PY C CG +F +S+L KH Sbjct: 170 HKRTHTGEKP--YDCKECGKAFTVPSSLQKHVRTHTGEKPYECSDCGKAFIDQSSLKKHT 227 Query: 240 KSH 242 +SH Sbjct: 228 RSH 230 Score = 60.5 bits (145), Expect = 2e-08 Identities = 28/65 (43%), Positives = 37/65 (56%), Gaps = 2/65 (3%) Query: 178 EAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYK 237 + H + +KP Y C C + S L+KH RSHTGE+PY C CG SF T S L Sbjct: 196 QKHVRTHTGEKP--YECSDCGKAFIDQSSLKKHTRSHTGEKPYECNQCGKSFSTGSYLIV 253 Query: 238 HRKSH 242 H+++H Sbjct: 254 HKRTH 258 Score = 58.5 bits (140), Expect = 8e-08 Identities = 28/67 (41%), Positives = 37/67 (55%), Gaps = 2/67 (2%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK- 1808 G Y C+ECG PS L+KH+RTHT +PY C C AF + +L KH +S K Sbjct: 176 GEKPYDCKECGKAFTVPSSLQKHVRTHTGEKPYECSDCGKAFIDQSSLKKHTRSHTGEKP 235 Query: 1809 -KCQETG 1814 +C + G Sbjct: 236 YECNQCG 242 Score = 57.0 bits (136), Expect = 2e-07 Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239 H + +KP Y C +C + ++ S L H R+HTGE+PY C CG +F S+L KH Sbjct: 142 HMRSHTGEKP--YECDHCGKSFSQSSHLNVHKRTHTGEKPYDCKECGKAFTVPSSLQKHV 199 Query: 240 KSH 242 ++H Sbjct: 200 RTH 202 Score = 56.6 bits (135), Expect = 3e-07 Identities = 24/51 (47%), Positives = 32/51 (62%) Query: 192 YICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242 Y C C + S L+KH+RSHTGE+PY C CG SF S+L H+++H Sbjct: 124 YECSDCGKAFIFQSSLKKHMRSHTGEKPYECDHCGKSFSQSSHLNVHKRTH 174 Score = 55.5 bits (132), Expect = 6e-07 Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 2/63 (3%) Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239 HK+ +K Y C+ C + S L+ H+R+HTGE+PY C C +F T +NL H+ Sbjct: 254 HKRTHTGEKT--YECKECGKAFRNSSCLRVHVRTHTGEKPYKCFQCEKAFSTSTNLIMHK 311 Query: 240 KSH 242 + H Sbjct: 312 RIH 314 Score = 54.3 bits (129), Expect = 1e-06 Identities = 27/67 (40%), Positives = 34/67 (50%), Gaps = 3/67 (4%) Query: 1739 SNEEYVYVRGR---GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKG 1795 S Y+ V R G Y C+ECG + S L+ H+RTHT +PY C C AF T Sbjct: 246 STGSYLIVHKRTHTGEKTYECKECGKAFRNSSCLRVHVRTHTGEKPYKCFQCEKAFSTST 305 Query: 1796 NLTKHMK 1802 NL H + Sbjct: 306 NLIMHKR 312 Score = 52.0 bits (123), Expect = 7e-06 Identities = 25/67 (37%), Positives = 34/67 (50%), Gaps = 2/67 (2%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK- 1808 G Y C +CG S LKKH+R+HT +PY C HC +F +L H ++ K Sbjct: 120 GEMPYECSDCGKAFIFQSSLKKHMRSHTGEKPYECDHCGKSFSQSSHLNVHKRTHTGEKP 179 Query: 1809 -KCQETG 1814 C+E G Sbjct: 180 YDCKECG 186 Score = 52.0 bits (123), Expect = 7e-06 Identities = 25/67 (37%), Positives = 34/67 (50%), Gaps = 2/67 (2%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK- 1808 G Y C+ CG + S L H RTHT +PY CK C AF +L KH+++ K Sbjct: 148 GEKPYECDHCGKSFSQSSHLNVHKRTHTGEKPYDCKECGKAFTVPSSLQKHVRTHTGEKP 207 Query: 1809 -KCQETG 1814 +C + G Sbjct: 208 YECSDCG 214 Score = 50.4 bits (119), Expect = 2e-05 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 2/67 (2%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK- 1808 G Y C +CG S LKKH R+HT +PY C C +F T L H ++ K Sbjct: 204 GEKPYECSDCGKAFIDQSSLKKHTRSHTGEKPYECNQCGKSFSTGSYLIVHKRTHTGEKT 263 Query: 1809 -KCQETG 1814 +C+E G Sbjct: 264 YECKECG 270 Score = 48.5 bits (114), Expect = 8e-05 Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 9/89 (10%) Query: 154 PEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRS 213 P + K F+ Q SLK +H E+ Y C C + + S L H R+ Sbjct: 207 PYECSDCGKAFI---DQSSLKKHTRSHTGEKP------YECNQCGKSFSTGSYLIVHKRT 257 Query: 214 HTGERPYPCGPCGFSFKTKSNLYKHRKSH 242 HTGE+ Y C CG +F+ S L H ++H Sbjct: 258 HTGEKTYECKECGKAFRNSSCLRVHVRTH 286 Score = 43.5 bits (101), Expect = 0.003 Identities = 23/63 (36%), Positives = 29/63 (46%), Gaps = 2/63 (3%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK- 1808 G Y C +CG S L H RTHT + Y CK C AF+ L H+++ K Sbjct: 232 GEKPYECNQCGKSFSTGSYLIVHKRTHTGEKTYECKECGKAFRNSSCLRVHVRTHTGEKP 291 Query: 1809 -KC 1810 KC Sbjct: 292 YKC 294 Score = 42.0 bits (97), Expect = 0.007 Identities = 16/32 (50%), Positives = 23/32 (71%) Query: 211 IRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242 +R+H+GE PY C CG +F +S+L KH +SH Sbjct: 115 VRTHSGEMPYECSDCGKAFIFQSSLKKHMRSH 146 Score = 35.4 bits (80), Expect = 0.68 Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 2/44 (4%) Query: 1773 IRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK--KCQETG 1814 +RTH+ PY C C AF + +L KHM+S K +C G Sbjct: 115 VRTHSGEMPYECSDCGKAFIFQSSLKKHMRSHTGEKPYECDHCG 158 >gi|138175817 zinc finger protein 236 [Homo sapiens] Length = 1845 Score = 67.8 bits (164), Expect = 1e-10 Identities = 80/383 (20%), Positives = 140/383 (36%), Gaps = 40/383 (10%) Query: 45 TQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQ-HPLTPA 103 T+E+ + LA QP G + ++ P + S + LPQ +T Sbjct: 830 TEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDT 889 Query: 104 F-MSPGKP--EHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGV 160 + P P + L + ST + ++ H QS L P D V Sbjct: 890 YHQQPQFPPVQQLQDSSTLE----------SQALSTSFHQQSLLQA------PSSDGMNV 933 Query: 161 PKVFVPRPSQVSLKPTEEAHK--KERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGER 218 + SQ L + + ++ + Q Y C YC++ K S L++H+RSHTGE+ Sbjct: 934 TTRLIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEK 993 Query: 219 PYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTE 278 PY C CG F + L H K+H +KA S +G + +P + Sbjct: 994 PYKCKLCGRGFVSSGVLKSHEKTHT-GVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYK 1052 Query: 279 GESTDSEEETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDP 338 + T+ + + ++G G E ++++ +S + Sbjct: 1053 CPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEV 1112 Query: 339 PPFVEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSE 398 F E + +P+++ T+ +K+ ++ + K I E R + Sbjct: 1113 ITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISE-----------------LRDK 1155 Query: 399 SAEQQVSPPNTNAKSYAEIIFGK 421 AE Q P + N +Y F K Sbjct: 1156 QAELQDEPKHANCCTYCPKSFKK 1178 Score = 62.4 bits (150), Expect = 5e-09 Identities = 38/96 (39%), Positives = 46/96 (47%), Gaps = 4/96 (4%) Query: 149 ASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYI--CQYCSRPCAKPSV 206 A I P E KV V S E K+ + Q K+ C YC + KPS Sbjct: 1124 AKIRPQESATVSEKVLVQ--SAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSD 1181 Query: 207 LQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242 L +H+R HTGE+PY C CG SF KS L H K+H Sbjct: 1182 LVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTH 1217 Score = 59.3 bits (142), Expect = 4e-08 Identities = 27/56 (48%), Positives = 33/56 (58%) Query: 187 QKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242 QKP + C C + AKPS L++H R HTGERP+ C C +F KS L H K H Sbjct: 1717 QKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKH 1772 Score = 57.4 bits (137), Expect = 2e-07 Identities = 24/51 (47%), Positives = 29/51 (56%) Query: 192 YICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242 Y C +C + KPS L +HIR HTGERP+ C CG +F K L H H Sbjct: 197 YSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKH 247 Score = 57.4 bits (137), Expect = 2e-07 Identities = 39/128 (30%), Positives = 58/128 (45%), Gaps = 10/128 (7%) Query: 124 PMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKE 183 P P+ S A P +Q P +S+ + P + + S L E+ K+ Sbjct: 406 PAAAHPNDSCHAKTSAPHAQN-PDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKK 464 Query: 184 RKPQKPGK---------YICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSN 234 + P PG ++C YC++ KPS L +HIR HT E+P+ C C +F KS Sbjct: 465 KSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKST 524 Query: 235 LYKHRKSH 242 L H K+H Sbjct: 525 LTAHIKTH 532 Score = 57.0 bits (136), Expect = 2e-07 Identities = 35/104 (33%), Positives = 48/104 (46%), Gaps = 9/104 (8%) Query: 174 KPTE-EAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTK 232 KP++ E H + ++P + C C + + S LQ H++ HTGERPY C C F K Sbjct: 1733 KPSQLERHSRIHTGERP--FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQK 1790 Query: 233 SNLYKHRKSHAHRIKAGLASGMG-----GEMYPHGLEMERIPGE 271 SN+ H K AH L G GE L +E + E Sbjct: 1791 SNMKLHMK-RAHSYAGALQESAGHPEQDGEELSRTLHLEEVVQE 1833 Score = 55.5 bits (132), Expect = 6e-07 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 12/224 (5%) Query: 192 YICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHA--HRIKAG 249 Y C YC R K L++HIRSHTGE+P+ C CG F + L H ++H K Sbjct: 657 YKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCL 716 Query: 250 LASG---MGGEMYPH-GLEMERIPGE-EFEEPTEGESTDSEEETSATSGHPAELSPRPKQ 304 + +G GG + H G+ + P + + T S + ++ H EL+ + +Q Sbjct: 717 ICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKT---HRYELAQQLQQ 773 Query: 305 PLLSSGLYSSGSHSSSHERCSLSQ-SSTAQSLEDPPPFVEPSSEHPLSHKPED-THTIKQ 362 ++ + S S + + Q + L V + E L +P+ T + Sbjct: 774 HQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGTEEA 833 Query: 363 KLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSP 406 L +L+++ DE F++P F A+Q P Sbjct: 834 GLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEP 877 Score = 54.3 bits (129), Expect = 1e-06 Identities = 24/48 (50%), Positives = 27/48 (56%) Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM 1801 Y C CG +KPS L +HIR HT RP+ C C AF KG L HM Sbjct: 197 YSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHM 244 Score = 53.9 bits (128), Expect = 2e-06 Identities = 42/154 (27%), Positives = 70/154 (45%), Gaps = 12/154 (7%) Query: 1660 ETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDA 1719 E+ ++T+ H ++ PSS T L+ Q++L + + + E+ + Sbjct: 909 ESQALSTSFHQQSLLQAPSSDGMNVTTR-----LIQESSQEELDLQAQGSQFLEDNEDQS 963 Query: 1720 PASQRGEPARIKIFEGGYKSNEEYVYVRGR-GRGKYVCEECGIRCKKPSMLKKHIRTHTD 1778 S R + +G KS+ +VR G Y C+ CG +LK H +THT Sbjct: 964 RRSYRCDYCN----KGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTG 1019 Query: 1779 VRPYVCKHCHFAFKTKGNLTKHMKSKAHSK--KC 1810 V+ + C C+ +F T G+LT+HM + K KC Sbjct: 1020 VKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKC 1053 Score = 53.5 bits (127), Expect = 2e-06 Identities = 26/60 (43%), Positives = 33/60 (55%), Gaps = 2/60 (3%) Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK--KCQ 1811 +VC C +KPS L +HIR HT +P+ C C AF K LT H+K+ K KCQ Sbjct: 482 HVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQ 541 Score = 50.4 bits (119), Expect = 2e-05 Identities = 46/203 (22%), Positives = 84/203 (41%), Gaps = 14/203 (6%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKK 1809 G + C +CG +LK HIRTHT ++ + C C+ AF T G+L +HM + Sbjct: 681 GEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRP 740 Query: 1810 -----CQETGVLEELEAEEGTSD---DLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDE 1861 CQ+T L ++ +L Q + + + ++++ D + + + + Sbjct: 741 YMCPYCQKT-FKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTV-DQQSMQASTQMQV 798 Query: 1862 DEDEDEEESQDELSRPSSEAP-PPGPPHALRADSSPI---LGPQPPDAPASGTEATRGSS 1917 + + DE E+ + EA P H + + + + L QP +A G A + Sbjct: 799 EIESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPL 858 Query: 1918 VSEAERLTASSCSMSSQSMPGLP 1940 ++ S + S GLP Sbjct: 859 RGHVDQFEEQSPAQQSFEPAGLP 881 Score = 49.3 bits (116), Expect = 5e-05 Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 6/71 (8%) Query: 172 SLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKT 231 ++K T AH K K K CQYC + + L+ HIR HTG RP+ C C F+T Sbjct: 520 AVKSTLTAHIKTHTGIKAFK--CQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRT 577 Query: 232 KSNLYKHRKSH 242 HRK+H Sbjct: 578 SG----HRKTH 584 Score = 48.9 bits (115), Expect = 6e-05 Identities = 25/63 (39%), Positives = 33/63 (52%), Gaps = 2/63 (3%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK- 1808 G Y C+ECG S L H++THT + + C C AF TKG+L HM+ +K Sbjct: 1191 GEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKP 1250 Query: 1809 -KC 1810 KC Sbjct: 1251 FKC 1253 Score = 47.0 bits (110), Expect = 2e-04 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 1/59 (1%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK 1808 G + C ECG + L+ H+ HT +P+ C C AF KGNL H++ + HS+ Sbjct: 221 GERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQ-RVHSE 278 Score = 46.6 bits (109), Expect = 3e-04 Identities = 20/50 (40%), Positives = 26/50 (52%) Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKS 1803 + C+ C LK HIR HT VRP+ C HC F+T G+ H+ S Sbjct: 538 FKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIAS 587 Score = 46.2 bits (108), Expect = 4e-04 Identities = 21/53 (39%), Positives = 27/53 (50%) Query: 1756 CEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK 1808 C C KKPS L +H+R HT +PY C C +F K L H+K+ K Sbjct: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQK 1221 Score = 46.2 bits (108), Expect = 4e-04 Identities = 21/49 (42%), Positives = 26/49 (53%) Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMK 1802 + C+ C KPS L++H R HT RP+ C C AF K L HMK Sbjct: 1722 FKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMK 1770 Score = 46.2 bits (108), Expect = 4e-04 Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 3/76 (3%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHS-- 1807 G + C C + S L+ H++ HT RPY C +C F K N+ HMK +AHS Sbjct: 1746 GERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK-RAHSYA 1804 Query: 1808 KKCQETGVLEELEAEE 1823 QE+ E + EE Sbjct: 1805 GALQESAGHPEQDGEE 1820 Score = 45.4 bits (106), Expect = 7e-04 Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 12/87 (13%) Query: 167 RPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCG 226 +PSQ++ H + ++P K C C + + LQ H+ HTGE+P+ C C Sbjct: 208 KPSQLT------RHIRIHTGERPFK--CSECGKAFNQKGALQTHMIKHTGEKPHACAFCP 259 Query: 227 FSFKTKSNLYKHRKSHAHRIKAGLASG 253 +F K NL +SH R+ + + +G Sbjct: 260 AAFSQKGNL----QSHVQRVHSEVKNG 282 Score = 45.4 bits (106), Expect = 7e-04 Identities = 18/53 (33%), Positives = 25/53 (47%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMK 1802 G+ + C C LK H+R HT +P+ C HC F+T G HM+ Sbjct: 1219 GQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQ 1271 Score = 45.1 bits (105), Expect = 9e-04 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 2/71 (2%) Query: 172 SLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKT 231 ++K T + H K QK + C CS + L+ H+R HTG +P+ C C F+T Sbjct: 1205 TVKSTLDCHVKTHTGQK--LFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRT 1262 Query: 232 KSNLYKHRKSH 242 H + H Sbjct: 1263 SGRRKTHMQFH 1273 Score = 44.7 bits (104), Expect = 0.001 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 2/63 (3%) Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239 H + +KP Y C C + S L H+++HTG++ + C C +F TK +L H Sbjct: 1185 HVRIHTGEKP--YKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHM 1242 Query: 240 KSH 242 + H Sbjct: 1243 RLH 1245 Score = 42.7 bits (99), Expect = 0.004 Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 2/59 (3%) Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK--KC 1810 Y C C KK LK+HIR+HT +P+ C C F + G L H+++ K KC Sbjct: 657 YKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKC 715 Score = 42.0 bits (97), Expect = 0.007 Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 2/63 (3%) Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239 H + +KP K C C R A S L HI++HTG + + C C SF T +L H Sbjct: 500 HIRIHTHEKPFK--CPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHI 557 Query: 240 KSH 242 + H Sbjct: 558 RLH 560 Score = 41.2 bits (95), Expect = 0.012 Identities = 16/49 (32%), Positives = 28/49 (57%) Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMK 1802 + C +C S L HI+THT ++ + C++C +F T G+L H++ Sbjct: 510 FKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIR 558 Score = 40.0 bits (92), Expect = 0.028 Identities = 16/49 (32%), Positives = 23/49 (46%) Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMK 1802 + C C L +H+ TH ++PY C C F+T + KHMK Sbjct: 1023 FSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMK 1071 Score = 39.3 bits (90), Expect = 0.047 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%) Query: 187 QKPGKYICQYCSRPCAKPSVLQKHIRSH-TGERPYPCGPCGFSFKTKSNLYKHRKSHA 243 Q P + C+ C K S Q+H+R H ++P+ C C +F + NL H+ +H+ Sbjct: 32 QVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHS 89 Score = 38.9 bits (89), Expect = 0.062 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 18/83 (21%) Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVR----------------PYVCKHCHFAFKT 1793 G ++ C+ C + S LK+H++TH +R Y C HC F+ Sbjct: 149 GTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQK 208 Query: 1794 KGNLTKHMKSKAHSK--KCQETG 1814 LT+H++ + KC E G Sbjct: 209 PSQLTRHIRIHTGERPFKCSECG 231 Score = 37.4 bits (85), Expect = 0.18 Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 4/53 (7%) Query: 1755 VCEECGIRCKKPSMLKKHIRTHTD----VRPYVCKHCHFAFKTKGNLTKHMKS 1803 +C ECG S L H+ H R + CK C F+T L +HMK+ Sbjct: 122 ICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKT 174 Score = 36.2 bits (82), Expect = 0.40 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 10/75 (13%) Query: 172 SLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSH----TGERPYPCGPCGF 227 SLK H+KE IC C S L H+ H G R + C C Sbjct: 107 SLKAHIMLHEKEEN------LICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKK 160 Query: 228 SFKTKSNLYKHRKSH 242 F+T S L +H K+H Sbjct: 161 EFETSSELKEHMKTH 175 Score = 35.0 bits (79), Expect = 0.89 Identities = 15/53 (28%), Positives = 24/53 (45%) Query: 194 CQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRI 246 C C++ ++ + L+ HI H E C CG F +S L H + H + Sbjct: 95 CPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQEL 147 Score = 34.3 bits (77), Expect = 1.5 Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 9/60 (15%) Query: 1756 CEECGIRCKKPSMLKKHIRTH-TDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQETG 1814 CE C + K S ++H+R H + +P+ C C F + NLT H KC +G Sbjct: 39 CEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLH--------KCTHSG 90 Score = 34.3 bits (77), Expect = 1.5 Identities = 15/37 (40%), Positives = 22/37 (59%), Gaps = 2/37 (5%) Query: 1780 RPYVCKHCHFAFKTKGNLTKHMKSKAHSK--KCQETG 1814 RPY C +CH A+K +L +H++S K KC + G Sbjct: 655 RPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCG 691 Score = 33.5 bits (75), Expect = 2.6 Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 5/65 (7%) Query: 1746 VRGRGRGKYVCEECGIRCKKPSMLKKHI-RTHTDVR---PYVCKHCHFAFKTKGNLTKHM 1801 ++ G + C C + L+ H+ R H++V+ Y C C FK+ G+L H+ Sbjct: 245 IKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHI 304 Query: 1802 KSKAH 1806 SK H Sbjct: 305 -SKMH 308 Score = 33.5 bits (75), Expect = 2.6 Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 2/51 (3%) Query: 1764 KKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK--KCQE 1812 KK L IR VR +VC +C F+ +L +H++ H K KC + Sbjct: 464 KKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQ 514 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 67.4 bits (163), Expect = 2e-10 Identities = 138/588 (23%), Positives = 201/588 (34%), Gaps = 67/588 (11%) Query: 774 QPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPP 833 QPR+ P S S++ +++ +S SS S+ + S P Q S Sbjct: 403 QPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRG 462 Query: 834 APHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTL 893 +P G S L + + Q+ V+ R P PPP+ QR + Sbjct: 463 SPSGGSTAEASDTLSIRSSGQLSGRSVSL---RKLKRPPPPPRRTHSLH-----QRGLAV 514 Query: 894 AQLPAEKLPPKKKRLRLAEMAQ--SSGESSFESSVPLSRSPSQESNVSLS-GSSRSASFE 950 P LPPK +R + ++ + ++G S + P +P+ LS G SR Sbjct: 515 PDGPL-GLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSR----- 568 Query: 951 RDDHGKAEAPSPSS---------DMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSH 1001 R SPSS + PK L + P E R S +SP S Sbjct: 569 RPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPE--RVTSLRSPGASV 626 Query: 1002 SAHMTETRSKSFDYGSLSLTGPSAPAPVAP----------PARVAPPERRKCFLVRQASL 1051 S+ +T S S D +GP P+ PA +PP + R + Sbjct: 627 SSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKP----RSPNP 682 Query: 1052 SRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPL 1111 + P + V P ++ S P + Q S + PP P PP Sbjct: 683 AAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPP 742 Query: 1112 GPTVPYTEALQVFHHPVAQTPLHEKPYLPPP------------------VSLFSFQHLVQ 1153 P A+ PL + + PPP + FS Sbjct: 743 PTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEP 802 Query: 1154 HEPGQSPEFFSTQAMSSLLSSPYSM-PPLPPSLFQAPPLPLQPTVLHPGQL-HLPQLMPH 1211 P SPE S+ A SS ++ + PP P APP P P PG + LPQ P Sbjct: 803 AGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAP-APASSAPGHVAKLPQKEPV 861 Query: 1212 PANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATG 1271 + P + P T S L + + P + PQ A Sbjct: 862 GCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPA-LGPSAPQKPLRRALSGRA 920 Query: 1272 SAGLSPSTEYSSDIRLPPVAPPAS---SSAPTSAPPLALPACPDTMVS 1316 S +PS+ + +RL + AS SSA + PP A P P + S Sbjct: 921 SPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPAS 968 Score = 57.8 bits (138), Expect = 1e-07 Identities = 159/653 (24%), Positives = 218/653 (33%), Gaps = 132/653 (20%) Query: 753 STKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSL 812 ST S S+ P E T P P GS G ++ E S + S+ Sbjct: 430 STLSSKGGSEGQP--ESSTASNSVVPPPQGGSGRGSPSGGSTAEAS---------DTLSI 478 Query: 813 EQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQ--------------PKLVRQPNIQVPEI 858 L G L + PPP P R HSL PK R+ Q+P Sbjct: 479 RSSGQLSGRSVSLRKLKRPPPPP--RRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRP 536 Query: 859 LVTEEPDRPDTEPEPP------------------PKEPEKTEEFQWPQRSQT-------- 892 T + P PP P+ PE+T SQ+ Sbjct: 537 PTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPK 596 Query: 893 -LAQLPA---EKLPPKKKRLRLAEMAQSSGESSFESSVPLSR--SPSQESNVSLSGSSRS 946 LA PA + PPK +R+ +S SS S S +PS S + + Sbjct: 597 GLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQIL-TPLG 655 Query: 947 ASFERDDHGKAEAP---SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSA 1003 F H K AP PS P P L P+ P S ++ SP + Sbjct: 656 DRFVIPPHPKVPAPFSPPPSKPRSPNPAAP-ALAAPAVVPGPV----STTDASPQSPPTP 710 Query: 1004 HMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSR---------- 1053 T T + S + P +P P P PP ++ +V S S Sbjct: 711 QTTLTPLQESPVISKDQSPPPSPPPSYHPP--PPPTKKPEVVVEAPSASETAEEPLQDPN 768 Query: 1054 --------PPESELEVAPKGRQE-------SEEPQPSSSKPSAKSSLSQISSAATSHGGP 1098 P E +L +A E S EP S P SS + SS+AT+ Sbjct: 769 WPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQ 828 Query: 1099 PGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHE-----KPYLPP------PVSLFS 1147 P PG PP P P + H VA+ P E K PP P+ S Sbjct: 829 P----PGSPDPPPAPPAPAPASSAPGH--VAKLPQKEPVGCSKGGGPPREDVGAPLVTPS 882 Query: 1148 FQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLF-QAPPLPLQPTVLHPGQLHLP 1206 +V+ +P T A+ S+P PL +L +A P+P + LH Sbjct: 883 LLQMVRLRSVGAPGGAPTPALGP--SAPQK--PLRRALSGRASPVPAPSSGLHAAVRLKA 938 Query: 1207 QLMPHPANIPFRQP---PSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKT 1263 + + QP P P P + ++ +S F + L+ P E+ + Sbjct: 939 CSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRN 998 Query: 1264 SLAPLATGSAGLSPSTEYSSDIRLPPVA--------PPASSS----APTSAPP 1304 +A L + S P S PPVA PPAS S P +APP Sbjct: 999 LVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPP 1051 Score = 54.3 bits (129), Expect = 1e-06 Identities = 148/605 (24%), Positives = 195/605 (32%), Gaps = 175/605 (28%) Query: 1867 EEESQDELSRP--------SSEAP-PPGPPHALRADSSPILGPQPPDAPASGTEATRGSS 1917 E + Q +L RP + AP PP P ++ SP +PP +P Sbjct: 526 ERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSP----------- 574 Query: 1918 VSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKP---VSPRRPWS---- 1970 ER + S SSQS G P L P L G A KP S R P + Sbjct: 575 ----ERTLSPSSGYSSQS--GTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSS 628 Query: 1971 -------------PSKEAGSR--PPLARKHSLTKNDSSPQRCSPA----REPQASAPSPP 2011 PS +G + PL + + + P SP R P +AP+ Sbjct: 629 SLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALA 688 Query: 2012 GLHVDPG--RGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPT 2069 V PG A P P Q TL PL + V+SK + P Y P Sbjct: 689 APAVVPGPVSTTDASPQSPPTPQT---TLTPL-----QESPVISKDQSPPPSPPPSYHP- 739 Query: 2070 RRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKL------ 2123 PP PP K +PSA E DP PP P P + Sbjct: 740 ----------PP---PPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMAD 786 Query: 2124 ------------------LSRSPETCASPWKAESRS-------------PSCSPGPAHPL 2152 S SPE +SP + S + P P PA P Sbjct: 787 FPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPA-PA 845 Query: 2153 SSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQAR----PGA 2208 SS P GH+ ++ PL+ +QMV+ R PG Sbjct: 846 SSAP--------GHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGG 897 Query: 2209 HPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSEL 2268 PT GP+A R A GR SP + S+ + ++ +L++ Sbjct: 898 APTPALGPSAPQKP-----------LRRALS-GRASPVPAPSSGLHAAVRLKACSLAAS- 944 Query: 2269 EGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPD----------TLPRPP 2318 EG + P PP+ AEP P SP + L RP Sbjct: 945 EG--------LSSAQPNGPPE---------AEPRPPQSPASTASFIFSKGSRKLQLERPV 987 Query: 2319 --------QGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRN 2370 Q A+ S + P P A PP+ R SVG AS +P R Sbjct: 988 SPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYP-RAEP 1046 Query: 2371 LSGEP 2375 L+ P Sbjct: 1047 LTAPP 1051 Score = 53.1 bits (126), Expect = 3e-06 Identities = 134/526 (25%), Positives = 166/526 (31%), Gaps = 129/526 (24%) Query: 1020 LTGPSAPA-PVAP---------------PARVAPPE-----RRKCFLVRQASLSRPPESE 1058 LTG + PA P++P P V PP +C L + S S Sbjct: 328 LTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHSASP 387 Query: 1059 LEVAPKGRQES-EEPQPSSSKPSAKS---SLSQISSAATSHGG----------------- 1097 V GR S PQP S PS+ S S SQ S S G Sbjct: 388 ASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTA 447 Query: 1098 -----PPGGKGPGQDRPPLGPTVPYTEAL------QVFHHPVAQTPLHEKPYLPPPVSLF 1146 PP G G+ P G T ++ L Q+ V+ L P PPP Sbjct: 448 SNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPP--PPPRRTH 505 Query: 1147 SFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLP 1206 S H+ G + + P +PP P Q P LP PT Sbjct: 506 SL-----HQRGLA-----------VPDGPLGLPPKPERK-QQPQLPRPPTTGGSEGAGAA 548 Query: 1207 QLMPHPAN--IP------FRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQ----LPGDV 1254 P+PAN +P R+PP SS SS P L PG Sbjct: 549 PCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKA 608 Query: 1255 ESHLPQ-----------IKTSLAPLATGSAGLSPSTEYSSDIRLP-------PVAP--PA 1294 + P+ + +SL L + S+ +PS I P P P PA Sbjct: 609 QPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPA 668 Query: 1295 SSSAPTSAPPLALPACPDTMVSLVVPVRVQT-----NMPSYGSAMYTTLSQILVTQSQGS 1349 S P S P PA P VVP V T P T L + V S Sbjct: 669 PFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQS 728 Query: 1350 SATVALPKFEEPP----SKGTTVCGADVHEVG----------PGPSGLSEEQSRA---FP 1392 P + PP V E P P EEQ + FP Sbjct: 729 PPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP 788 Query: 1393 TP-YLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGS 1437 P V PE G S S E + S SSS+A + + P GS Sbjct: 789 PPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQ--IQPPGS 832 Score = 48.1 bits (113), Expect = 1e-04 Identities = 124/531 (23%), Positives = 172/531 (32%), Gaps = 52/531 (9%) Query: 1874 LSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSS 1933 LSR S + P +L SS + PQP S + T S S ++ + + ++SS Sbjct: 377 LSRCSLHSASPASVRSLGRFSS-VSSPQPRSRHPSSSSDTWSHSQS-SDTIVSDGSTLSS 434 Query: 1934 QSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSP--SKEAGSRPPLARKHSLTKND 1991 + GS + S S V P + S S GS + S+ + Sbjct: 435 KG------------GSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSG 482 Query: 1992 SSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELA----P 2047 R R+ + P P H RG+ A+P G PL L P P Sbjct: 483 QLSGRSVSLRKLKRPPPPPRRTHSLHQRGL-AVPDG-------PLGLPPKPERKQQPQLP 534 Query: 2048 RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLG 2107 R EG P +P W PG + R P P S + + G Sbjct: 535 RPPTTGGSEGAGAAPCPP-NPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPT- 592 Query: 2108 LDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHI 2167 L P+ L P P K PE S S S S SS A D G Sbjct: 593 LPPKGLAGPPASPGKAQPPKPERVTS---LRSPGASVSSSLTSLCSSSSDPAPSDRSGPQ 649 Query: 2168 LARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGG 2227 + + F P +P P P A A P ++PGP + + Sbjct: 650 ILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPAL--AAPAVVPGPVSTTDASPQSP 707 Query: 2228 GSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRP 2287 + T QE S +S S P + P E T P + Sbjct: 708 PTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASE-TAEEPLQD 766 Query: 2288 PDWTPHGTGAPAEPTPTHSPCTPPDTL--------PRPPQGRR------AAQSWSPRLES 2333 P+W P AP E + + PP+ P P G AA S S Sbjct: 767 PNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQ 826 Query: 2334 PRAPTNPEPSATPPLDR--SSSVGCLAEASARFPARTRNLSGEPRTRQDSP 2382 + P +P+P PP SS+ G +A+ + P G PR +P Sbjct: 827 IQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAP 877 Score = 40.4 bits (93), Expect = 0.021 Identities = 86/395 (21%), Positives = 129/395 (32%), Gaps = 68/395 (17%) Query: 727 PPAFESTKSQFGSPGPSDAARNLPL----------ESTKSPAEPSKSV-PSLEGPTGFQP 775 P F S+ SP P+ A P S +SP P ++ P E P + Sbjct: 667 PAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKD 726 Query: 776 RTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQ--------PSGLEGEDKPLAQ 827 ++P P T K V++ S+ E ++ Q P E +D +A Sbjct: 727 QSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMAD 786 Query: 828 FPSPP--------PAPHGRSAHSLQPKLVRQP--NIQVPEILVTEEPDRPDTEPEPPP-- 875 FP P P P G S P+LV P + L + P PD P PP Sbjct: 787 FPPPEEAFFSVASPEPAGPSG---SPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPA 843 Query: 876 --------------KEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESS 921 KEP + P R A L P + +RL + G + Sbjct: 844 PASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVT---PSLLQMVRLRSVGAPGGAPT 900 Query: 922 -----FESSVPLSRS--------PSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRP 968 PL R+ P+ S + + ++ S + + P+ + P Sbjct: 901 PALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEP 960 Query: 969 KPLGTHMLTVP---SHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLS-LTGPS 1024 +P + T S ++ R S ++ + E RS S + P Sbjct: 961 RPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPK 1020 Query: 1025 APAPVAPPARVAPPERRKCFLVRQASLSRPPESEL 1059 AP PVA V P R L+ PP + L Sbjct: 1021 APPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGL 1055 Score = 37.4 bits (85), Expect = 0.18 Identities = 90/360 (25%), Positives = 123/360 (34%), Gaps = 75/360 (20%) Query: 34 SVPYPGSGTAATQESPA-QELLAPQPFPGPSS------------VLREGSQEKTGQQQK- 79 S P P + QESP + +P P P PS V+ S +T ++ Sbjct: 706 SPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQ 765 Query: 80 ----PPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVA 135 PP PP +S P AF S PE GPSGS Sbjct: 766 DPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPE--------------PAGPSGS--- 808 Query: 136 PGL--HPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKP---QKPG 190 P L P + + A I P P P P P+ S P A +++P K G Sbjct: 809 PELVSSPAASSSSATALQIQPPGSPDPPPA-PPAPAPASSAPGHVAKLPQKEPVGCSKGG 867 Query: 191 KYICQYCSRPCAKPSVLQK-HIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAG 249 + P PS+LQ +RS P G S K L + A + A Sbjct: 868 GPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKP-LRRALSGRASPVPAP 926 Query: 250 LASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLS- 308 +SG+ + + SE +SA P E PRP Q S Sbjct: 927 -SSGLHAAVRLKACSL----------------AASEGLSSAQPNGPPEAEPRPPQSPAST 969 Query: 309 -SGLYSSGSHSSSHER-------CSLSQSSTAQ----SLEDPP--PFVEPSSEHPLSHKP 354 S ++S GS ER L ++ A+ S + PP P P + P++ KP Sbjct: 970 ASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKP 1029 Score = 37.4 bits (85), Expect = 0.18 Identities = 63/255 (24%), Positives = 83/255 (32%), Gaps = 29/255 (11%) Query: 1873 ELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSE--AERLTASSCS 1930 ++ P S PPP PP A S+P + P G G + A +T S Sbjct: 826 QIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQ 885 Query: 1931 MSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKN 1990 M G P G AP ++ + +S R P+ +G + K Sbjct: 886 MVRLRSVGAP--GGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAA 943 Query: 1991 DSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQL----SPLTLCPLGRELA 2046 P P+A P PP GS +LQL SP T L R L Sbjct: 944 SEGLSSAQPNGPPEAE-PRPP--QSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLV 1000 Query: 2047 PRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGL 2106 +S+ P P+ SP + P A P PP P SPS Sbjct: 1001 AELRSISE---QRPPQAPKKSP--KAPPPVARKPSVGVPP-------PASPSYPR----- 1043 Query: 2107 GLDPRVLFPPAPLPH 2121 +P P LPH Sbjct: 1044 -AEPLTAPPTNGLPH 1057 >gi|10047144 sal-like 4 [Homo sapiens] Length = 1053 Score = 67.0 bits (162), Expect = 2e-10 Identities = 67/216 (31%), Positives = 92/216 (42%), Gaps = 55/216 (25%) Query: 132 SFVAPGLHP------QSQLLPSHASIIPPEDLPGVP--------------------KVFV 165 S ++PGL P +++LP+ S +P LP P K Sbjct: 304 SSLSPGLAPFTLKPDGTRVLPNVMSRLPSALLPQAPGSVLFQSPFSTVALDTSKKGKGKP 363 Query: 166 PRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPC 225 P S V +KP +EA + K C+YCS+ S LQ H+RSHTGERP+ C C Sbjct: 364 PNISAVDVKPKDEAALYKHK--------CKYCSKVFGTDSSLQIHLRSHTGERPFVCSVC 415 Query: 226 GFSFKTKSNLYKHRKSHAHRIKAG----------LASGMGGEMYPHGLEMERIPGEEFEE 275 G F TK NL H H ++KA +A+G G P+ L + + +E Sbjct: 416 GHRFTTKGNLKVHFHRHP-QVKANPQLFAEFQDKVAAGNG---IPYALSVP----DPIDE 467 Query: 276 PTEGESTDSEEETSATS-GHPAELSPRPKQPLLSSG 310 P+ S DS+ TS G P LS L+ G Sbjct: 468 PS--LSLDSKPVLVTTSVGLPQNLSSGTNPKDLTGG 501 Score = 60.5 bits (145), Expect = 2e-08 Identities = 44/141 (31%), Positives = 64/141 (45%), Gaps = 10/141 (7%) Query: 106 SPGKPEHLLEGSTWQ-LVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLP---GVP 161 S G P++L G+ + L PG + PG P+S+ P+ + P + P G Sbjct: 482 SVGLPQNLSSGTNPKDLTGGSLPGD----LQPGPSPESEGGPTLPGVGPNYNSPRAGGFQ 537 Query: 162 KVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYP 221 P P +LK + ++ P + C C R + S L+ H R+HTGERP+ Sbjct: 538 GSGTPEPGSETLKLQQLVENIDKATTDPNE--CLICHRVLSCQSSLKMHYRTHTGERPFQ 595 Query: 222 CGPCGFSFKTKSNLYKHRKSH 242 C CG +F TK NL H H Sbjct: 596 CKICGRAFSTKGNLKTHLGVH 616 Score = 54.3 bits (129), Expect = 1e-06 Identities = 37/99 (37%), Positives = 50/99 (50%), Gaps = 4/99 (4%) Query: 145 LPSHASIIPPEDLP-GVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAK 203 LPS PP + VP FV PS +S T + R+ K ++ C C + + Sbjct: 825 LPSTFIRAPPTYVKVEVPGTFVG-PSTLSPGMTPLLAAQPRRQAK--QHGCTRCGKNFSS 881 Query: 204 PSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242 S LQ H R+HTGE+P+ C CG +F TK NL H +H Sbjct: 882 ASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVHYMTH 920 Score = 52.4 bits (124), Expect = 5e-06 Identities = 76/310 (24%), Positives = 111/310 (35%), Gaps = 66/310 (21%) Query: 1767 SMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM---------KSKAHSKKCQET---- 1813 S LK H RTHT RP+ CK C AF TKGNL H+ K++ CQ+ Sbjct: 579 SSLKMHYRTHTGERPFQCKICGRAFSTKGNLKTHLGVHRTNTSIKTQHSCPICQKKFTNA 638 Query: 1814 ------------GVLEELEAEEGTSDDLFQDSE----GREGSEAVEEHQFSDLEDSDSDS 1857 G + E D F SE G GS H +D Sbjct: 639 VMLQQHIRMHMGGQIPNTPLPENPCD--FTGSEPMTVGENGSTGAICH-----DDVIESI 691 Query: 1858 DLDEDEDEDEEESQDELSRP----SSEAPPPGPPHALRADSSPILGPQPPDAPASGTEAT 1913 D++E ++ S ++ P S +P G D+ +GP P + G + Sbjct: 692 DVEEVSSQEAPSSSSKVPTPLPSIHSASPTLGFAMMASLDAPGKVGPAPFNLQRQG---S 748 Query: 1914 RGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSK 1973 R + E++ LT S S+ +G S D S++ +SP S ++ Sbjct: 749 RENGSVESDGLTNDSSSL----------MGDQEYQSRSPDILETTSFQALSPAN--SQAE 796 Query: 1974 EAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSP--------PGLHVDPGR---GMG 2022 S+ P A + + +S + + P +P PG V P GM Sbjct: 797 SIKSKSPDAGSKAESSENSRTEMEGRSSLPSTFIRAPPTYVKVEVPGTFVGPSTLSPGMT 856 Query: 2023 ALPCGSPRLQ 2032 L PR Q Sbjct: 857 PLLAAQPRRQ 866 Score = 48.1 bits (113), Expect = 1e-04 Identities = 50/177 (28%), Positives = 71/177 (40%), Gaps = 40/177 (22%) Query: 1646 AALSLLRSK---QKVSKETYTMATAPHPEAGRLVPSSSR-------KPRMTEV------H 1689 AA++LL K Q +S + A PH S S KP T V Sbjct: 270 AAVALLSQKAGSQGLSLDALKQAKLPHANIPSATSSLSPGLAPFTLKPDGTRVLPNVMSR 329 Query: 1690 LPSLVSPEG------QKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSNEEY 1743 LPS + P+ Q + V + ++G +G+P I + K +E Sbjct: 330 LPSALLPQAPGSVLFQSPFSTVALDTSKKG----------KGKPPNISAVDVKPK-DEAA 378 Query: 1744 VYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800 +Y K+ C+ C S L+ H+R+HT RP+VC C F TKGNL H Sbjct: 379 LY-------KHKCKYCSKVFGTDSSLQIHLRSHTGERPFVCSVCGHRFTTKGNLKVH 428 Score = 48.1 bits (113), Expect = 1e-04 Identities = 22/45 (48%), Positives = 25/45 (55%) Query: 1756 CEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800 C CG S L+ H RTHT +P+VC C AF TKGNL H Sbjct: 872 CTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVH 916 Score = 32.7 bits (73), Expect = 4.4 Identities = 54/236 (22%), Positives = 84/236 (35%), Gaps = 49/236 (20%) Query: 191 KYICQYCSRPCAKPSVLQKHIRSHTG----ERPYPCGPCGFSFKTKSNLYKHRKSHAHRI 246 ++ C C + +LQ+HIR H G P P PC F+ + ++ Sbjct: 625 QHSCPICQKKFTNAVMLQQHIRMHMGGQIPNTPLPENPCDFTGSEPMTVGEN-------- 676 Query: 247 KAGLASGMGGEMYPHGLEMERI-----PGEEFEEPTEGESTDSEEET-----SATSGHPA 296 G + + +++E + P + PT S S T A+ P Sbjct: 677 --GSTGAICHDDVIESIDVEEVSSQEAPSSSSKVPTPLPSIHSASPTLGFAMMASLDAPG 734 Query: 297 ELSPRPKQPLLSSGLYSSGSHSS---SHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHK 353 ++ P P L G +GS S +++ SL QS P +E +S LS Sbjct: 735 KVGPAPFN-LQRQGSRENGSVESDGLTNDSSSLMGDQEYQSRS--PDILETTSFQALSPA 791 Query: 354 PEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNT 409 +IK K SP + ES SR+E E + S P+T Sbjct: 792 NSQAESIKSK------------------SPDAGSKAESSENSRTE-MEGRSSLPST 828 >gi|239743293 PREDICTED: mucin 12 [Homo sapiens] Length = 5478 Score = 67.0 bits (162), Expect = 2e-10 Identities = 296/1379 (21%), Positives = 446/1379 (32%), Gaps = 196/1379 (14%) Query: 276 PTEGESTDSEEETSATSGHPAELSPR----PKQPLLSS-GLYSSGSHSSSHERCSLSQSS 330 P+ ST S +T+ H + S + P+ S G S+ SHSS+ S + S+ Sbjct: 3455 PSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPST 3514 Query: 331 TAQSLEDPPPFVEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTE 390 T+ +E+P + +H P+ + T + S + L S S Sbjct: 3515 TSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVL 3574 Query: 391 SGYFSRSE----SAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTE 446 G + S S E P +T +E T + P P +T Sbjct: 3575 LGESTTSPISSGSMETTALPGSTTTPGLSE--------------KSTTFHSSPRSPATTL 3620 Query: 447 DKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLYR 506 S V H T A D++ + R S + SS S ++L Sbjct: 3621 SPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLS--RHSTTSHSSPGSTDTTLL- 3677 Query: 507 EPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHHPFRGSYS---F 563 P S+ + + E + H S + L + + ST H GS F Sbjct: 3678 -PASTTTSGSSQES---TTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF 3733 Query: 564 DDHITDSEALSHSS--HVFTSHPRMLKRQPAIELP-LGGEYSSEEPGPSSKDTA-SKPSD 619 D T S + S+ H T PR + P L GE ++ + P+S T S PS Sbjct: 3734 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPST 3793 Query: 620 EVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKPISAGT 679 P E T G + +K + + + P SA + Sbjct: 3794 ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS-----SPDASGTTPSSAHS 3848 Query: 680 HTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFESTKS--QF 737 TS E + P S + G+T TP P S S Sbjct: 3849 TTSGRGESTTSRISPGSTEITTLPGST--TTPGLSEASTTFYSSPRSPTTTLSPASMTSL 3906 Query: 738 GSPGPSDAARNLP--LESTKSPAEPSKSVPSLEGPT------GFQPRTPKPGSGSES-GK 788 G S +R+ P ST SPA + S E T G T P S + S + Sbjct: 3907 GVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRR 3966 Query: 789 ERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLV 848 E TT HT+ F + + SGL E FP P + Sbjct: 3967 EEPTTFHSRPASTHTTLFTEDST---TSGLTEES---TAFPGSPAS-------------- 4006 Query: 849 RQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRL 908 +P L T + T P T P RS T + L E P Sbjct: 4007 --TQTGLPATLTTADLGEEST---TFPSSSGSTGTKLSPARS-TTSGLVGESTP------ 4054 Query: 909 RLAEMAQSSGESSFESSVPLSRSPSQESNV-SLSGSSRSASFERDDHGKAEAPSPSSDMR 967 + ++ SS E++ P + S S++S S S A+ + SS Sbjct: 4055 --SRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSH 4112 Query: 968 PKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHS------AHMTETRSKSFDYGSLSLT 1021 +P TH P S Q P SHS A ++ + + G S T Sbjct: 4113 SQPGSTHTTAFPD------STTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTT 4166 Query: 1022 GPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELE--VAPKGRQESEEPQPSSSKP 1079 S+P + P + LV ++ + L + P + + S++ Sbjct: 4167 FHSSPGDT--ETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQ 4224 Query: 1080 SAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYL 1139 S SS S ++ P RP PT ++ + T +H P Sbjct: 4225 SWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP-- 4282 Query: 1140 PPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLH 1199 F T++ +S+L + P+ + LP T Sbjct: 4283 ----------------GATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT-- 4324 Query: 1200 PGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLP 1259 L + + P R P + L TSS +S +S + PG + + Sbjct: 4325 ---AGLSEKSTTFYSSP-RSPDTTLSPASTTSSGVSE------ESTTSHSRPGSMHTTAF 4374 Query: 1260 QIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDT------ 1313 T++ P + + S S+ S+D L P + ASS P S + P +T Sbjct: 4375 PSSTTM-PGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDN 4433 Query: 1314 -----MVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTV 1368 ++ PV T P +TTLS T QG S T P SK TT Sbjct: 4434 TTASGLLEASTPVHSSTGSP------HTTLSPAGSTTRQGESTTFQ----SWPNSKDTT- 4482 Query: 1369 CGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGS 1428 P P + AF V L S SS SS+T G S Sbjct: 4483 ---------PAP----PTTTSAF--------VELSTTSHGSPSSTPTTHFSASSTTLGRS 4521 Query: 1429 KRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGN 1488 + + S T T R S +E ST+ PE + Sbjct: 4522 EESTTVHSSPVATATTPSPAR------STTSGLVEESTTYHSSPGSTQTMHFPESNTTSG 4575 Query: 1489 QGQ--GRRELEMLSSLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGL 1546 +G+ ++SS PS T + P S+ ++PGS A +P S R Sbjct: 4576 RGEESTTSHSSTTHTISSAPSTTSALVEEP---TSYHSSPGSTATTHFPDSSTTSGRSEE 4632 Query: 1547 TPLSVKKEDSKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVS 1605 + S +D+ LP+ + S L L E+++ P S S + P TT +S Sbjct: 4633 STASHSSQDATGTIVLPARSTTSVL-LGESTTSPISS----GSMETTALPGSTTTPGLS 4686 Score = 63.5 bits (153), Expect = 2e-09 Identities = 385/1776 (21%), Positives = 570/1776 (32%), Gaps = 311/1776 (17%) Query: 729 AFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPT--------GFQPRTPKP 780 AF + + G S A+ ++P ST + P + PS GP G+ T P Sbjct: 322 AFPDSTTMPGVSQESTASHSIP-GSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLP 380 Query: 781 GSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPP---PAPHG 837 + + SG +T S ++ S S EGE +PS PAP G Sbjct: 381 DNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTH----EGEPTTFQSWPSSKDTSPAPSG 436 Query: 838 RSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKT---EEFQWPQRSQTLA 894 ++ ++ L T P + P T E P S +A Sbjct: 437 TTSAFVK--------------LSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVA 482 Query: 895 QLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQ-------ESNVSLSGSSRSA 947 A PP A+S+ E S RSP ES+ + S SA Sbjct: 483 T--ATTPPP----------ARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESA 530 Query: 948 SFERDD-HGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAH-- 1004 +F H K+ PS ++ + + + + + H SE+S SHS+ Sbjct: 531 TFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEES-KASHSSPDA 589 Query: 1005 MTETRSKSFDYGSLSLTGPSAPAPV--------APPARVAPPERRKCFLVRQASLSRPPE 1056 M T + S+ L G S P+P+ A P P + +S P Sbjct: 590 MATTVLPAGSTPSV-LVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDT 648 Query: 1057 SELEVAPKGRQESEEPQPSSSKPSAKSS-----------LSQISSAATSHGGPPGGK-GP 1104 + L + SEE S S+P + + LSQ S+A+ S GP P Sbjct: 649 THLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSP 708 Query: 1105 GQDRPP-LGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQH--LVQHEPGQSPE 1161 G LGP YT FH T E LP + + H +SP Sbjct: 709 GSTTASSLGPE--YT----TFHSRPGST---ETTLLPDNTTASGLLEASMPVHSSTRSPH 759 Query: 1162 FFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPP 1221 + A S+ + PS P P T P H + P Sbjct: 760 TTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTT----SAFVEPSTTSHGS-------P 808 Query: 1222 SFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVES-HLPQIKT----------------- 1263 S +P + ++ + +SG L +S PG ++ H P+ T Sbjct: 809 SSIPTTHISARSTTSG--LVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTH 866 Query: 1264 --SLAPLATGSAGLSPSTEYSSDIRLPPVA-PPASSSAPTSAPPLALPACPDTMVSLVVP 1320 S AP T + P++ +SS P +S+++ S A + D ++V+P Sbjct: 867 TISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 926 Query: 1321 VRVQTNMPSYGSAMYTTLSQ--ILVTQSQGSSATVALPK-----FEEPPSKGTTVCGADV 1373 R T++ G + + +S + T GS+ T L + P S TT+ A Sbjct: 927 ARSTTSV-LLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPAST 985 Query: 1374 HEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGT-SLSSESILSLEGSSSTAGGSKRVL 1432 SG+SEE + + P P+ T LS S S S+ G + L Sbjct: 986 TS-----SGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTS----HSSPGSTDTTL 1036 Query: 1433 SPAGSLELTMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQG 1492 PA + T Q+ + D L P S T+ G+ H N G Sbjct: 1037 LPASTT--TSGPSQESTTSHSSSGSTDTALS---PGST--TALSFGQESTTFH-SNPGST 1088 Query: 1493 RRELEMLSSLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRG-LTPLSV 1551 L S+ SS + + ++ GS P S P +G T Sbjct: 1089 HTTLFPDSTTSSG---------IVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQT 1139 Query: 1552 KKEDSKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNY 1611 + P PS A + P+ E+++ S FP+ TT+ S Sbjct: 1140 HPASTHTTPSPPSTA---TAPVEESTTY----HRSPGSTPTTHFPASSTTSGHS------ 1186 Query: 1612 IKPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPE 1671 + + I H+ +S G S + G + +++ + T E Sbjct: 1187 -EKSTIFHSSPDAS---GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSE 1242 Query: 1672 AGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIK 1731 A SS R P T +SP L E+ R +P S + Sbjct: 1243 ASTTFYSSPRSPTTT-------LSPASMTSLGVGEESTTSRSQP-----GSTHSTVSPAS 1290 Query: 1732 IFEGGYKSNEEYVYVRGRGRGKYVC----EECGIRCKKPSML-KKHIRTHTDVRPYVCKH 1786 G VY RG + + ++P+ + THT + Sbjct: 1291 TTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTL------- 1343 Query: 1787 CHFAFKTKGNLTKHMKSKAHSKKCQETGVLEELE-AEEGTSDDLFQDSEGREGSEAVEEH 1845 T LT+ + S +TG+ L A+ G F S G G++ Sbjct: 1344 -FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTK----- 1397 Query: 1846 QFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDA 1905 S + S + S + + P S P P ++ P+ PDA Sbjct: 1398 -LSPARSTTSGLVGESTPSRLSPSSTETTTLPGS----PTTPSLSEKSTTFYTSPRSPDA 1452 Query: 1906 PASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSP 1965 S T S VSE S +S S PG P + T S LS +P + Sbjct: 1453 TLSPATTT-SSGVSEE--------SSTSHSQPGSTHTTAFP----DSTTTSDLSQEPTTS 1499 Query: 1966 RRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALP 2025 S EA P SL + S+ SP P + G + P Sbjct: 1500 HSSQG-STEATLSPGSTTASSLGQQ-STTFHSSPGDTETTLLPDDT---ITSGLVEASTP 1554 Query: 2026 CGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESP----- 2080 S L TL P A E TT P S T PG +P Sbjct: 1555 THSSTGSLHT-TLTPASSTSAGLQE-----ESTTFQSWPSSSDTTPSPPGTTAAPVEVST 1608 Query: 2081 -----PRSAPPGKWALA----GPGSPSAGEHGPGLGLDPRVLFPPA---------PLPHK 2122 P S P ++ + G S H G LFP P Sbjct: 1609 TYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP-GATGTALFPTRSATSVLVGEPTTSP 1667 Query: 2123 LLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLH 2182 + S S ET A P + S + P + L +EE+ SH Sbjct: 1668 ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPG 1727 Query: 2183 SQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLT----GAREAQ 2238 S H T A PG+ T +PG + + S GS T G+ A Sbjct: 1728 STHTT----------------AFPGS--TTMPGVSQESTASHSSPGSTDTTLSPGSTTAS 1769 Query: 2239 ERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAP 2298 G S T SS + + T +S L P TG +PH T +P Sbjct: 1770 SLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSS-TG---------SPHTTLSP 1819 Query: 2299 A-------EPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRS 2351 A E T S + DT+P PP A S ++ PS+TP S Sbjct: 1820 AGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELS-------TTSHGSPSSTPTTHFS 1872 Query: 2352 SSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGS 2387 +S L + + + P +P P+ S Sbjct: 1873 ASSTTLGRSE-----ESTTVHSSPVATATTPSPARS 1903 Score = 61.6 bits (148), Expect = 9e-09 Identities = 282/1339 (21%), Positives = 452/1339 (33%), Gaps = 189/1339 (14%) Query: 310 GLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTIKQKLALRLS 369 G S+ SHSS+ S + S+T+ +E+P + +H P+ + T + Sbjct: 854 GEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR------- 906 Query: 370 ERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRT 429 E++ S S+ +T + + + T+ S + + T Sbjct: 907 ------SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM---------ETT 951 Query: 430 AMLTATSTQPLLPLST-------EDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEID 482 A+ +T+T L ST +L P S + V E T + + T+ D Sbjct: 952 ALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPD 1011 Query: 483 SVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHS 542 S S +S SP S+ L S T + H S + L + Sbjct: 1012 STTTPGLSRHSTTSHSSPGST--DTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGST 1069 Query: 543 MPSAACTISTPHHPFRGSYS---FDDHITDSEALSHSS--HVFTSHPRMLKRQPAIELP- 596 + ST H GS F D T S + S+ H T PR + P Sbjct: 1070 TALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG 1129 Query: 597 LGGEYSSEEPGPSSKDTA-SKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKR 655 L GE ++ + P+S T S PS P E T G T + + + + ++ Sbjct: 1130 LQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG-STPTTHFPASSTTSGHSEK 1188 Query: 656 DNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKR 715 S + + P ++G T+P + S S G+T E+T L Sbjct: 1189 -----------STIFHSSPDASG--TTPSSAHSTTSGRGESTTSRISPGST-EITTLPGS 1234 Query: 716 RKEKSLGDEEEPPAFESTKSQFGSPGP-SDAARNLPLESTKSPAEPSKSVPSLEGPTGFQ 774 L E + S +S + P S + + EST S ++P S S P Sbjct: 1235 TTTPGL-SEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG-STHSTVSPAS-- 1290 Query: 775 PRTPKPGSGSESGKERRTT--SKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPP 832 T PG ES ++ S E +V H+++ + + GE+ P Sbjct: 1291 --TTTPGLSEESTTVYSSSRGSTETTVFPHSTT----------TSVHGEE---------P 1329 Query: 833 PAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQT 892 H R A + T P P + P + + + Sbjct: 1330 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS 1389 Query: 893 LAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERD 952 + KL P A+S+ S P SPS +L GS + S Sbjct: 1390 SSGSTGTKLSP----------ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEK 1439 Query: 953 DHGKAEAP-SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSK 1011 +P SP + + P + ++ S S S P +H+ ++ + Sbjct: 1440 STTFYTSPRSPDATLSPATTTSSGVSEES----------STSHSQPGSTHTTAFPDSTTT 1489 Query: 1012 SFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASL--SRPPESELEVAPKGRQES 1069 S D T S+ + A ++P L +Q++ S P ++E + P S Sbjct: 1490 S-DLSQEPTTSHSSQG--STEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITS 1546 Query: 1070 EEPQPSSSKPSAKSSL-SQISSAATSHGGPPGGKGPGQDRP--------PLGPTVPYTEA 1120 + S+ S+ SL + ++ A+++ G Q P P G T E Sbjct: 1547 GLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEV 1606 Query: 1121 LQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQS-PEFFSTQAMSSLLSSPYSMP 1179 +H + TP + V PG + F T++ +S+L + Sbjct: 1607 STTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTS 1666 Query: 1180 PLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFF 1239 P+ + LP T L + + P R P + L TSS +S Sbjct: 1667 PISSGSTETTALPGSTTT-----AGLSEKSTTFYSSP-RSPDTTLSPASTTSSGVSE--- 1717 Query: 1240 LPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAP 1299 +S + PG + T++ P + + S S+ S+D L P + ASS P Sbjct: 1718 ---ESTTSHSRPGSTHTTAFPGSTTM-PGVSQESTASHSSPGSTDTTLSPGSTTASSLGP 1773 Query: 1300 TSAPPLALPACPDT-----------MVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQG 1348 S + P +T ++ PV T P +TTLS T QG Sbjct: 1774 ESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSP------HTTLSPAGSTTRQG 1827 Query: 1349 SSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGT 1408 S T F+ PS T+ P P + AF V L Sbjct: 1828 ESTT-----FQSWPSSKDTM---------PAP----PTTTSAF--------VELSTTSHG 1861 Query: 1409 SLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPC 1468 S SS SS+T G S+ + S T T R S +E Sbjct: 1862 SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPAR------STTSGLVEESTAY 1915 Query: 1469 SVVLTSTEDGKRPEKSHLGNQGQGRR--ELEMLSSLSSDPSDTKEIPPLPHPALSHGTAP 1526 ST+ PE S + + R ++SS PS T + P S+ ++P Sbjct: 1916 HSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEP---TSYHSSP 1972 Query: 1527 GSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSSLPLSETSSRPAKSQEG 1586 GS A +P S R + S +D+ LP+ + S L L E+++ P S Sbjct: 1973 GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVL-LGESTTSPISS--- 2028 Query: 1587 TDSKKVLQFPSLHTTTNVS 1605 S + P TT +S Sbjct: 2029 -GSMETTALPGSTTTPGLS 2046 Score = 57.8 bits (138), Expect = 1e-07 Identities = 357/1703 (20%), Positives = 516/1703 (30%), Gaps = 317/1703 (18%) Query: 6 SVKGTKKAEGSPRKRLTKG-------EAIQTSVSSSVPYPGSGTAATQESPAQELL---- 54 S G+ + SP + T G + S + + PGS T + + Sbjct: 1389 SSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPR 1448 Query: 55 APQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLL 114 +P P++ G E++ P S H + P T H Sbjct: 1449 SPDATLSPATTTSSGVSEESSTSHSQP------GSTHTTAFPDSTTTSDLSQEPTTSHSS 1502 Query: 115 EGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPS-----HASIIPPEDLP-GVPKVFVPRP 168 +GST + P GS A L QS S +++P + + G+ + P Sbjct: 1503 QGSTEATLSP------GSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTH 1556 Query: 169 SQV-SLKPT-EEAHKKERKPQKPGKYICQYCSRPCAKPS-----VLQKHIRSHTGERPYP 221 S SL T A Q+ + S PS + + RP Sbjct: 1557 SSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSS 1616 Query: 222 CGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGES 281 FS + + L + +S G G ++P + GE P S Sbjct: 1617 TPTTHFS-ASSTTLGRSEESTTVHSSPGAT---GTALFPTRSATSVLVGEPTTSPISSGS 1672 Query: 282 TDSEEETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPF 341 T ET+A G K S+ YSS S S +S+ S E Sbjct: 1673 T----ETTALPGSTTTAGLSEK----STTFYSS-PRSPDTTLSPASTTSSGVSEESTTSH 1723 Query: 342 VEPSSEHPLSHKPEDTHT-IKQKLALRLSERKKVIDEQAFLSPGSKGSTESG-----YFS 395 P S H + T + Q+ S LSPGS ++ G + S Sbjct: 1724 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPGST---DTTLSPGSTTASSLGPESTTFHS 1780 Query: 396 RSESAEQQVSPPNTNAKSYAEIIF----------------GKCGRIGQRTAMLTATSTQP 439 S E + P NT A E G R G+ T + S++ Sbjct: 1781 SPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKD 1840 Query: 440 LLPLSTEDKPSLV---------PLSVPRTQVIEHITKL------ITINEAVVDTSEIDSV 484 +P + V P S P T T L T++ + V T+ S Sbjct: 1841 TMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS- 1899 Query: 485 KPRRSSLSR--------RSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVP 536 P RS+ S SS S ++ + E ++ + S S H S+ P Sbjct: 1900 -PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPP--- 1955 Query: 537 LLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELP 596 S SA T +H GS + H DS S S T+ I LP Sbjct: 1956 -----STTSALVEEPTSYHSSPGSTA-TTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 2009 Query: 597 -------LGGEYSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICG 649 L GE ++ S +T + P P GL K + Sbjct: 2010 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTP-----------GLSEKSTTFH----- 2053 Query: 650 ARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLEL 709 + P S T SP + S E S H + G+T Sbjct: 2054 ----------------------SSPRSPATTLSPASTTSSGVSEE-STTSHSRPGST--- 2087 Query: 710 TPLRKRRKEKSLGDEEEPPAFES-TKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLE 768 + D P + + SPG +D +T P++ S + S Sbjct: 2088 -------HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSP 2140 Query: 769 GPTGFQPRTPKPGSGSE-SGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQ 827 G T PGS + S + TT HT+ F DS +E + + Sbjct: 2141 GSTD---TALSPGSTTALSFGQESTTFHSSPGSTHTTLFP--DSTTSSGIVEASTRVHSS 2195 Query: 828 FPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWP 887 SP +L P P +Q P T P PP EE Sbjct: 2196 TGSPRT--------TLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTY 2247 Query: 888 QRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSA 947 RS P P A S+ E S SP SG++ S+ Sbjct: 2248 HRSP--GSTPTTHFP-----------ASSTTSGHSEKSTIFHSSP------DASGTTPSS 2288 Query: 948 SFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTE 1007 + H S+ R P T + T+P S + S S + ++ Sbjct: 2289 A-----HSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSP 2343 Query: 1008 TRSKSFDYGSLSLTGPSAP----APVAPPARVAPPERRKCFLVRQASLSRPPESELEVAP 1063 S G S T S P + V+P + P + V +S P +E V P Sbjct: 2344 ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSS---PGSTETTVFP 2400 Query: 1064 KGRQES---EEPQPSSSKPSA--------KSSLSQISSAATSHGGPPGGKGPGQDRPPLG 1112 + S EEP S+P++ S+ S ++ +T+ G P G P Sbjct: 2401 RTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG--LPATL 2458 Query: 1113 PTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLL 1172 T E F T P ++ +S L Sbjct: 2459 TTADLGEESTTFPSSSGSTGTTLSP---------------------------ARSTTSGL 2491 Query: 1173 SSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANI--PFRQPPSFLPMPYPT 1230 + L PS + LP PT P L R P + L T Sbjct: 2492 VGESTPSRLSPSSTETTTLPGSPTT--------PSLSEKSTTFYTSPRSPDATLSPATTT 2543 Query: 1231 SSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPV 1290 SS +S +S + PG + T+ L+ S S S+ S+D L P Sbjct: 2544 SSGVSE------ESSTSHSQPGSTHTTAFPDSTTTPGLSRHST-TSHSSPGSTDTTLLPA 2596 Query: 1291 APPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSS 1350 + S + S + P DT +S T S+G T S S GS+ Sbjct: 2597 STTTSGPSQESTTSHSSPGSTDTALS-----PGSTTALSFGQESTTFHS------SPGST 2645 Query: 1351 ATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPV--TLPERKGT 1408 T P + S G VH P S P T P T Sbjct: 2646 HTTLFP--DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHT 2703 Query: 1409 SLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPC 1468 + S S + ST +P + T S EK Sbjct: 2704 TPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTT-----------SGHSEK------- 2745 Query: 1469 SVVLTSTED--GKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALSHGTAP 1526 S + S+ D G P +H G+G +S P T EI LP + G + Sbjct: 2746 STIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS-----PGST-EITTLPGSTTTPGLSE 2799 Query: 1527 GSEALKEYPQ-PSGKPHRRGLTPLSVKKED--SKEQP-DLPSLAPPSSLP---LSETSSR 1579 S P+ P+ +T L V +E S+ QP S P+S LSE S+ Sbjct: 2800 ASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTT 2859 Query: 1580 PAKSQEGTDSKKVLQFPSLHTTT 1602 S G+ V FP TT+ Sbjct: 2860 VYSSSPGSTETTV--FPRSTTTS 2880 Score = 54.7 bits (130), Expect = 1e-06 Identities = 299/1432 (20%), Positives = 448/1432 (31%), Gaps = 197/1432 (13%) Query: 279 GESTDSEEETSATSGHPAELSPRPK-QPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLED 337 G +T +T+ H + SP P ++ S ++SH R + ++ Sbjct: 3595 GSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTT 3654 Query: 338 PPPFVEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAF------LSPGSK----- 386 P S+ S DT + S ++ + LSPGS Sbjct: 3655 TPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSF 3714 Query: 387 GSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQ-RTAMLTATSTQPLL---- 441 G + + S S + P +T + E G RT + A+ST P L Sbjct: 3715 GQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 3774 Query: 442 ------PLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRS 495 P ST PS P S T + E+ S S + Sbjct: 3775 TAFQTHPASTHTTPS--PPS----------TATAPVEESTTYHRSPGSTPTTHFPASSTT 3822 Query: 496 SMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHH 555 S S KS+++ + P+ S + PS+A R S S ST Sbjct: 3823 SGHSEKSTIFH---------SSPDASGTT----PSSAHSTTSGRGESTTSRISPGSTEIT 3869 Query: 556 PFRGSYSFDDHITDSEALSHSSHVFTSHPRM----LKRQPAIELPLGGEYSSEEPGPSSK 611 GS T + LS +S F S PR L L +G E ++ P S Sbjct: 3870 TLPGS-------TTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGST 3922 Query: 612 DTASKPSDEVEP---KESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSE 668 + P+ P +ES + G V R ++ + + Sbjct: 3923 HSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRP------ 3976 Query: 669 LQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEE-- 726 A THT+ E S + + T L LG+E Sbjct: 3977 --------ASTHTTLFTEDSTTSGLT-EESTAFPGSPASTQTGLPATLTTADLGEESTTF 4027 Query: 727 PPAFESTKSQF--------GSPGPSDAARNLPLESTKSPAEPSKSVPSL-EGPTGF--QP 775 P + ST ++ G G S +R P + + S + PSL E T F P Sbjct: 4028 PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 4087 Query: 776 RTP----KPGSGSESG-KERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPS 830 R+P P + + SG E +TS HT++F S + SGL E P+ Sbjct: 4088 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTT---SGLSQE-------PT 4137 Query: 831 PPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRS 890 + G + +L P ++ P +T P E P S Sbjct: 4138 TSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHS 4197 Query: 891 QTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQES----NVSLSGSSRS 946 T L P L E +S+ S+ SS + SP + VS + SR Sbjct: 4198 ST-GSLHTTLTPASSTSTGLQE--ESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRP 4254 Query: 947 ASFERDDHGKAEAP----SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHS 1002 +S + S+ + P T P+ A + SP S S Sbjct: 4255 SSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRS--ATSVLVGEPTTSPISSGS 4312 Query: 1003 AHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQA--SLSRPPESELE 1060 T + G + +P +P ++P + ++ S SRP Sbjct: 4313 TETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTT 4372 Query: 1061 VAPKGRQE---SEEPQPSSSKPSAKSSLSQISSAATSHGGPPGG---KGPGQDRPPLGPT 1114 P S+E S S P + + S S GP PG L P Sbjct: 4373 AFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPD 4432 Query: 1115 VPYTEALQVFHHPVAQTPLHEKPYLPPPVSLF------SFQHLVQHEPGQSPEFFSTQAM 1168 L PV + L P S +FQ + +T A Sbjct: 4433 NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAF 4492 Query: 1169 SSLLSSPYSMPPLPPSL-FQAPPLPL----QPTVLHPGQLHLPQLMPHPANIPFRQPPSF 1223 L ++ + P P+ F A L + T +H + P PA R S Sbjct: 4493 VELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPV-ATATTPSPA----RSTTSG 4547 Query: 1224 L---PMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTE 1280 L Y +S + P + + + SH T + +T SA + T Sbjct: 4548 LVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTS 4607 Query: 1281 YSSDIRLPPVA--PPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTL 1338 Y S P +S+++ S A + D ++V+P R T++ S T Sbjct: 4608 YHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES----TT 4663 Query: 1339 SQILVTQSQGSSATVALPKFEEPPS---KGTTVCGADVH------EVGPGPSGLSEEQSR 1389 S I S GS T ALP P K TT + G SEE + Sbjct: 4664 SPI----SSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTT 4719 Query: 1390 AFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKR 1449 +P P R TS E + S+ G ++ + P S R Sbjct: 4720 VHSSPVATATTPSPARSTTSGLVEESTAYH---SSPGSTQTMHFPESSTA-------SGR 4769 Query: 1450 VKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKS-------HLGNQGQGRRELEMLSSL 1502 +E S + + P S E+ S H E ++ Sbjct: 4770 SEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTAS 4829 Query: 1503 SSDPSDTKEIPPLPHPALSHGTAPG--SEALKEYPQP-------SGKPHRRGLTPLSVKK 1553 S P DT I PLP +H T G +E+ Y P + GL+ S Sbjct: 4830 HSSP-DTNGITPLP----AHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTIL 4884 Query: 1554 EDSKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVS 1605 S PD P+S+ S S P +S FP+ TT+ +S Sbjct: 4885 YSSSRSPD--QTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLS 4934 Score = 43.9 bits (102), Expect = 0.002 Identities = 272/1401 (19%), Positives = 444/1401 (31%), Gaps = 225/1401 (16%) Query: 269 PGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSS---GLYSSGS----HSSSH 321 PG +T S ++T H + SPR SS GL + H +S Sbjct: 2642 PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPAST 2701 Query: 322 ERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFL 381 S+ +E+ + P +H P + T SE+ + Sbjct: 2702 HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGH------SEKSTIFHSSPDA 2755 Query: 382 SPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLL 441 S + S S R ES ++SP +T + + G G A T S+ P Sbjct: 2756 SGTTPSSAHSTTSGRGESTTSRISPGSTEITT----LPGSTTTPGLSEASTTFYSS-PRS 2810 Query: 442 PLSTEDKPSLVPLSV-------------------PRTQVIEHITKLITINEAVVDTSEID 482 P +T S+ L V P + +++ T + S Sbjct: 2811 PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTET 2870 Query: 483 SVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHS 542 +V PR ++ S R E P ++ + P S+H+ + + L + P P Sbjct: 2871 TVFPRSTTTSVRG--EEP-TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG 2927 Query: 543 MPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYS 602 +P+ T + T + S S+ S R + L GE + Sbjct: 2928 LPATLTTA-----------DLGEESTTFPSSSGSTGTTLSPAR------STTSGLVGEST 2970 Query: 603 SEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHK 662 PSS +T + P P SE + ++ + ++ +H Sbjct: 2971 PSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSH- 3029 Query: 663 KYYCSELQIAKPISAGTHTSPEA-EKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSL 721 ++P S T P++ S + EP + H G+T E T SL Sbjct: 3030 ---------SQPGSTHTTAFPDSTTTSGLSQEPTAS--HSSQGST-EATLSPGSTTASSL 3077 Query: 722 GDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPG 781 G ++ F S+ P D L + T + S P+ TG T P Sbjct: 3078 G--QQSTTFHSS--------PGDTETTLLPDDTITSGLVEASTPT-HSSTGSLHTTLTPA 3126 Query: 782 SGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLA----QFPSPPPAPHG 837 S + +G + +T+ + S SD+ P G ++ PS P H Sbjct: 3127 SSTSAGLQEESTTFQ-------SWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHF 3179 Query: 838 RSAHSLQPKLVRQPNI-QVPEILVTE-EPDRPDT-----EPEPPPKEPEKTEEFQWPQRS 890 ++ + + + P T P R T EP P TE P S Sbjct: 3180 SASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALP-GS 3238 Query: 891 QTLAQLPAEKL----PPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRS 946 T A L + P+ L+ + +S S ES+ SR P + GS+ Sbjct: 3239 TTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSR-PGSTHTTAFPGSTTM 3297 Query: 947 ASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMT 1006 ++ +P S+D P T T S P + + P + + + Sbjct: 3298 PGVSQESTASHSSPG-STDTTLSPGST---TASSLGPES-----TTFHSGPGSTETTLLP 3348 Query: 1007 ETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPES-ELEVAPKG 1065 + + S G L + P + +P ++P S +R ES + P Sbjct: 3349 DNTTAS---GLLEASTPVHSSTGSPHTTLSP----------AGSTTRQGESTTFQSWPNS 3395 Query: 1066 RQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFH 1125 + + P P+ S+ ++S+ TSHG P PT ++ + Sbjct: 3396 KDTTPAP------PTTTSAFVELST--TSHGSPSS-----------TPTTHFSASSTTLG 3436 Query: 1126 HPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLP-PS 1184 T +H P P +S + ++ SSP S + P Sbjct: 3437 RSEESTTVHSSPVATATTP----------SPARSTTSGLVEESTTYHSSPGSTQTMHFPE 3486 Query: 1185 LFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQS 1244 + T H H P + +P S+ P T++ P S Sbjct: 3487 SDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATT-----HFPDSS 3541 Query: 1245 QFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPP 1304 + + SH Q ATG+ L + S + +P +S S T+A P Sbjct: 3542 TTSGRSEESTASHSSQD-------ATGTIVLPARSTTSVLLGESTTSPISSGSMETTALP 3594 Query: 1305 --LALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQ--GSSATVALPKFEE 1360 P + + R S S + +S+ T GS+ T A P Sbjct: 3595 GSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTT 3654 Query: 1361 PPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEG 1420 P GLS + + +P LP TS SS+ + Sbjct: 3655 TP-------------------GLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTT--- 3692 Query: 1421 SSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKR 1480 S S++G + LSP + L+ + ++ + +V ST Sbjct: 3693 SHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAST----- 3747 Query: 1481 PEKSHLGNQGQGRRELEMLSSLS-----------SDPSDTKEIPPLPHPALSHGTAPGSE 1529 + H + G R L SS S + P+ T P P S TAP E Sbjct: 3748 --RVH-SSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPP----STATAPVEE 3800 Query: 1530 ALKEYPQPSGKP--HRRGLTPLSVKKEDS---KEQPDLPSLAPPSSLPLSETSSRPAKSQ 1584 + + P P H + S E S PD P S+ + S+ Sbjct: 3801 STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR 3860 Query: 1585 EGTDSKKVLQFPSLHTTTNVS 1605 S ++ P TT +S Sbjct: 3861 ISPGSTEITTLPGSTTTPGLS 3881 Score = 43.9 bits (102), Expect = 0.002 Identities = 352/1805 (19%), Positives = 566/1805 (31%), Gaps = 255/1805 (14%) Query: 6 SVKGTKKAEGSPRKRLTKGEAIQTSVS-SSVPYPGSGTAATQESPAQELLAPQPFPGPSS 64 S G+ + P T G +++ S SS + S +T + +E + PG ++ Sbjct: 3474 SSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTA 3533 Query: 65 VLR-EGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVD 123 S +G+ ++ + + LP T + + GS Sbjct: 3534 TTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTAL 3593 Query: 124 PMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKE 183 P GS PGL +S H+S P P + S S +EE+ Sbjct: 3594 P------GSTTTPGLSEKSTTF--HSS-------PRSPATTLSPASTTSSGVSEESTTSH 3638 Query: 184 RKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHA 243 +PG P + + SH+ S T + + SH+ Sbjct: 3639 ---SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHS 3695 Query: 244 HRIKAGLASGMGG----EMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELS 299 A G PG +T S ++T H + S Sbjct: 3696 SSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS 3755 Query: 300 PRPKQPLLSS---GLYSSGS----HSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSH 352 PR SS GL + H +S S+ +E+ + P +H Sbjct: 3756 PRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTH 3815 Query: 353 KPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAK 412 P + T SE+ + S + S S R ES ++SP +T Sbjct: 3816 FPASSTTSGH------SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT 3869 Query: 413 SYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITIN 472 + G G A T S+ P P +T S+ L V E T Sbjct: 3870 TLP----GSTTTPGLSEASTTFYSS-PRSPTTTLSPASMTSLGVGE----ESTTSRSQPG 3920 Query: 473 EAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTA 532 S + P S S SP S+ S + + E+ P ST Sbjct: 3921 STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTH 3980 Query: 533 PPVPLLRSHSMPSAACTIST--PHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRML--K 588 L S S ST P P +T ++ L S F S K Sbjct: 3981 --TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTAD-LGEESTTFPSSSGSTGTK 4037 Query: 589 RQPAIELPLG--GEYSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECN 646 PA G GE + PSS +T + P P SE + ++ Sbjct: 4038 LSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 4097 Query: 647 ICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEK-SQIEHEPWSQMMHYKLGT 705 + ++ +H ++P S T P++ S + EP + H G+ Sbjct: 4098 TTTSSGVSEESSTSH----------SQPGSTHTTAFPDSTTTSGLSQEPTTS--HSSQGS 4145 Query: 706 TLELTPLRKRRKEKSLGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVP 765 T E T SLG ++ F S+ P D L + T + S P Sbjct: 4146 T-EATLSPGSTTASSLG--QQSTTFHSS--------PGDTETTLLPDDTITSGLVEASTP 4194 Query: 766 SLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGE-DKP 824 + TG T P S + +G + +T+ + SS + + S + + E Sbjct: 4195 T-HSSTGSLHTTLTPASSTSTGLQEESTTFQ----SWPSSSDTTPSPPSTTAVPVEVSTT 4249 Query: 825 LAQFPSPPPAPHGRSAHSLQPKLVRQPNIQV-PEILVTEE-PDRPDT-----EPEPPPKE 877 PS P H ++ + + + P T P R T EP P Sbjct: 4250 YHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPIS 4309 Query: 878 PEKTEEFQWPQRSQTLAQLPAEKLP----PKKKRLRLAEMAQSSGESSFESSVPLSRSPS 933 TE P S T A L + P+ L+ + +S S ES+ SR S Sbjct: 4310 SGSTETTALPG-STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGS 4368 Query: 934 QE-----SNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREM 988 S+ ++ G S+ ++ G + LG T S Sbjct: 4369 MHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS-------- 4420 Query: 989 RRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQ 1048 SP + + + + + S G L + P + +P ++P Sbjct: 4421 -------SPGSTETTLLPDNTTAS---GLLEASTPVHSSTGSPHTTLSPA---------- 4460 Query: 1049 ASLSRPPESE-LEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQD 1107 S +R ES + P + + P P+ S+ ++S+ TSHG P Sbjct: 4461 GSTTRQGESTTFQSWPNSKDTTPAP------PTTTSAFVELST--TSHGSPSST------ 4506 Query: 1108 RPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQA 1167 PT ++ + T +H P P +S + Sbjct: 4507 -----PTTHFSASSTTLGRSEESTTVHSSPVATATTP----------SPARSTTSGLVEE 4551 Query: 1168 MSSLLSSPYSMPPLP-PSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPM 1226 ++ SSP S + P + T H H P + +P S+ Sbjct: 4552 STTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSS 4611 Query: 1227 P-------YPTSSALSSG----------------FFLPLQSQFALQLPGDVESHLPQ--I 1261 P +P SS S LP +S ++ L S + + Sbjct: 4612 PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM 4671 Query: 1262 KTSLAPLATGSAGLSP--STEYSSDIRLPPVAPPASSSA-PTSAPPLALPACPDTMVSLV 1318 +T+ P +T + GLS +T +SS P ASS+ S + + P + Sbjct: 4672 ETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTP 4731 Query: 1319 VPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGT---TVCGADVHE 1375 P R T+ S Y + S GS+ T+ P+ + T + H Sbjct: 4732 SPARSTTSGLVEESTAYHS--------SPGSTQTMHFPESSTASGRSEESRTSHSSTTHT 4783 Query: 1376 VGPGPS---GLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAG------ 1426 + PS L EE + +P PE TS SE + S T G Sbjct: 4784 ISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPA 4843 Query: 1427 ---GSKRV-------LSPAGSLELTMET-------QQQKRVKEEEASKADEKLELVKPCS 1469 S R+ +SP GS+E T+ + + + + D+ L P S Sbjct: 4844 HFTTSGRIAESTTFYISP-GSMETTLASTATTPGLSAKSTILYSSSRSPDQTLS---PAS 4899 Query: 1470 VVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALSHGT-APGS 1528 + +S E + L +Q + +S ++ + P + T +PGS Sbjct: 4900 MTSSSISG----EPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGS 4955 Query: 1529 EALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPP--SSLPLSETSSRPAKSQEG 1586 + Q PH + + LS S P L + SS +ET++ + Sbjct: 4956 ITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMS 5015 Query: 1587 TDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHAD--RRSSVYAGWCISLYNPNLPGVST 1644 S++ FP T+ + P + D + S+ + + LP ST Sbjct: 5016 IHSQQSTPFPDSPGFTHT-------VLPATLTTTDIGQESTAFHSSSDATGTTPLPARST 5068 Query: 1645 KAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLAR 1704 + L E T +P P L P+SS +TE SP + Sbjct: 5069 ASDLV---------GEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVS 5119 Query: 1705 VEKEE 1709 E E Sbjct: 5120 TESLE 5124 Score = 41.6 bits (96), Expect = 0.010 Identities = 62/273 (22%), Positives = 90/273 (32%), Gaps = 45/273 (16%) Query: 1868 EESQDELSRPSSE----APPPGPPHALRADSSPILGPQPPDA-----PASGTEATRGSSV 1918 EES S+P S +P L +S+ + P P + T + RG Sbjct: 2353 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEP 2412 Query: 1919 SE-------------AERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSP 1965 + E T S + S + PG P S + + L+ + Sbjct: 2413 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSP-------ASTQTGLPATLTTADLGE 2465 Query: 1966 RRPWSPSKEAGSRPPLARKHSLTKN---DSSPQRCSPAREPQASAP-SPPGLHVDPGRGM 2021 PS + L+ S T +S+P R SP+ + P SP + Sbjct: 2466 ESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTT 2525 Query: 2022 GALPCGSPRLQLSPLTLCPLG--------RELAPRAHVLSKLEGTTDPGLPRYSPTRRWS 2073 SP LSP T G H + + TT PGL R+S T S Sbjct: 2526 FYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSS 2585 Query: 2074 PGQAESPPRSAPPGKWALAGPGSPSAGEH-GPG 2105 PG ++ + P +GP S H PG Sbjct: 2586 PGSTDT---TLLPASTTTSGPSQESTTSHSSPG 2615 Score = 33.9 bits (76), Expect = 2.0 Identities = 130/539 (24%), Positives = 176/539 (32%), Gaps = 85/539 (15%) Query: 1869 ESQDELSRPSSEAPPPGPPHALRA--DSSPILGPQPPDAPASGTEATRGSSVSEAERLTA 1926 ES S PSS+ P PP A + S P P + A+ + E T Sbjct: 1828 ESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTV 1887 Query: 1927 SSCSMSSQSMPGLPWLGPA---PLGSVEKDTGSALSYKPVSPRRPWSP-SKEAGSRPPLA 1982 S +++ + P PA G VE+ T A P S + P S A R + Sbjct: 1888 HSSPVATATTPS-----PARSTTSGLVEEST--AYHSSPGSTQTMHFPESSTASGRSEES 1940 Query: 1983 R-KHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPL 2041 R HS T + S SP A P H PG S P + Sbjct: 1941 RTSHSSTTHTIS----SPPSTTSALVEEPTSYHSSPG---------STATTHFPDSSTTS 1987 Query: 2042 GR-ELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAG 2100 GR E + +H GT LP S T SP S AL PGS + Sbjct: 1988 GRSEESTASHSSQDATGTIV--LPARSTTSVLLGESTTSPISSGSMETTAL--PGSTTT- 2042 Query: 2101 EHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSAL 2160 PGL + F +P RSP T SP S S +H SRP S Sbjct: 2043 ---PGLS-EKSTTFHSSP-------RSPATTLSPASTTSSGVSEESTTSH---SRPGST- 2087 Query: 2161 HDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAW 2220 H A + L HS +P G P + T GP+ Sbjct: 2088 -----HTTAFPDSTTTPGLSRHSTTSHSSP-------GSTDTTLLPAS--TTTSGPSQES 2133 Query: 2221 VSGFSGGGSDLT----GAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKE 2276 + S GS T G+ A G+ S T SS + T SS + + Sbjct: 2134 TTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAS-TRV 2192 Query: 2277 RERTGG-------GPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSP 2329 TG P T P TH+ +PP T P + +S + Sbjct: 2193 HSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVE-----ESTTY 2247 Query: 2330 RLESPRAPTNPEPSATPP---LDRSSSVGCLAEASARFPARTRNLS---GEPRTRQDSP 2382 PT P+++ ++S+ +AS P+ + + GE T + SP Sbjct: 2248 HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISP 2306 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 67.0 bits (162), Expect = 2e-10 Identities = 135/596 (22%), Positives = 190/596 (31%), Gaps = 100/596 (16%) Query: 755 KSPAEPS-KSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSF------- 806 K PA P ++ P E +P S S + + T K ++ +S Sbjct: 36 KQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKR 95 Query: 807 --EKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEP 864 EK S + + K Q S P +P S + V P+ + + Sbjct: 96 QREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDI---DQ 152 Query: 865 DRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFES 924 D T P P + +++ Q+ AQ PA + P + SS Sbjct: 153 DNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT----------GVTPAPSSAPP 202 Query: 925 SVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPS-PSSDMRPKPLGTHMLTVPSHHP 983 P +P + + S + ++AP+ P + P P TH+ P+ HP Sbjct: 203 GTPQLPTPGPTPSATAVPPQGSPT-------ASQAPNQPQAPTAPVP-HTHIQQAPALHP 254 Query: 984 HAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKC 1043 SP H T S PSAP+ PP P Sbjct: 255 QRPPSPHPPPHPSP---HPPLQPLTGSAG---------QPSAPSHAQPPLHGQGPPGPHS 302 Query: 1044 F----LVRQAS----LSRPPESELEVAPKGRQESEE-PQPSSSKPSAKSSLSQISSAATS 1094 L++ PP++ AP G + P S P+++S+L Q Sbjct: 303 LQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL-QSQQPPRE 361 Query: 1095 HGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHP---VAQTPLHEKPYLPPPVSLFSFQHL 1151 PP +PP +P A Q HP +P LPPP +L L Sbjct: 362 QPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 421 Query: 1152 -VQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMP 1210 H P P S L S P PP L Q+ LP P P LH Q+ P Sbjct: 422 STHHPPSAHPPPLQLMPQSQPLP---SSPAQPPGLTQSQNLPPPPASHPPTGLH--QVAP 476 Query: 1211 HPANIPFRQ-------PPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKT 1263 P PF Q PP P P++S +G PG T Sbjct: 477 QP---PFAQHPFVPGGPPPITPPTCPSTSTPPAG-------------PG----------T 510 Query: 1264 SLAPLATGSAGLSPSTEYSSDIRLPPVAPPA----SSSAPTSAPPLALPACPDTMV 1315 S P +G+A S S LP V + P S PP P+ V Sbjct: 511 SAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTV 566 Score = 54.3 bits (129), Expect = 1e-06 Identities = 133/588 (22%), Positives = 193/588 (32%), Gaps = 129/588 (21%) Query: 1792 KTKGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLE 1851 K+ + + S S K Q V + E + TS S+ + E + S+ E Sbjct: 77 KSAKKVKEEASSPLKSNKRQREKVASDTEEADRTS------SKKTKTQEISRPNSPSEGE 130 Query: 1852 DSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSS---PILGPQPP--DAP 1906 SDS DE + + D+ +R +S + P + +DSS +L QPP AP Sbjct: 131 GESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAP 190 Query: 1907 ASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPR 1966 T A S + P LP GP P + GS + + +P Sbjct: 191 TGVTPAP----------------SSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ--APN 232 Query: 1967 RPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQ-ASAPSPPGLHVDPGRGMGALP 2025 +P +P+ P+ H + +PA PQ +P PP P Sbjct: 233 QPQAPT------APVPHTHI---------QQAPALHPQRPPSPHPP-------------P 264 Query: 2026 CGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPP---R 2082 SP L PLT G+ AP +H L G PG P ++ P Sbjct: 265 HPSPHPPLQPLT-GSAGQPSAP-SHAQPPLHGQGPPG-----------PHSLQAGPLLQH 311 Query: 2083 SAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPL-----PHKLLSRSPETCASPWKA 2137 PP + L P A + LG P +P L L S+ P A Sbjct: 312 PGPPQPFGL----PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPA 367 Query: 2138 ESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIG 2197 P P P P+ P H H+ + ++ ++LP P L P+ Sbjct: 368 PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLP--------PPPALKPLS 419 Query: 2198 GIQMVQARPGAHPTLLP-GPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPV 2256 + P AHP L P + + LT ++ P + V Sbjct: 420 SLS-THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP----PPASHPPTGLHQV 474 Query: 2257 AKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPR 2316 A F + PG PP TP P P+ T +P P T + Sbjct: 475 APQPPFAQHPFV---------------PGGPPPITP-----PTCPS-TSTPPAGPGTSAQ 513 Query: 2317 PPQGRRAAQSWS-----------PRLESPRAPTNPEPSATPPLDRSSS 2353 PP AA S +++ EP + PP RS S Sbjct: 514 PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPS 561 Score = 42.0 bits (97), Expect = 0.007 Identities = 98/449 (21%), Positives = 149/449 (33%), Gaps = 92/449 (20%) Query: 724 EEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQ-PRTPKPGS 782 + +PPA ++ +P PS A P T P + +VP PT Q P P+ + Sbjct: 181 QAQPPALQAPTGV--TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 238 Query: 783 GSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPH------ 836 + + HT ++Q L + +P + P P P+PH Sbjct: 239 ---------------APVPHT-------HIQQAPALHPQ-RPPSPHPPPHPSPHPPLQPL 275 Query: 837 -GRSAHSLQPKLVRQP----------NIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQ 885 G + P + P ++Q +L P +P P + Sbjct: 276 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP 335 Query: 886 WPQRSQTLAQLPA------EKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESN-V 938 T QLPA + PP+++ L A +A + + +P +P + Sbjct: 336 AAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPP 395 Query: 939 SLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPN 998 LSG S + A P P + L TH PS HP ++ + + Sbjct: 396 HLSGPSPFSM-------NANLPPPPALKPLSSLSTH--HPPSAHPPPLQLMPQSQPLPSS 446 Query: 999 VSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESE 1058 + +T+ S +L P A P +VAP +PP ++ Sbjct: 447 PAQPPGLTQ---------SQNLPPPPASHPPTGLHQVAP---------------QPPFAQ 482 Query: 1059 LEVAPKGRQESEEPQ-PSSSKPSA---KSSLSQISSAATSHGGPPGGKGPGQDRPPLGPT 1114 P G P PS+S P A S+ S AA S G GG PL Sbjct: 483 HPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTV 537 Query: 1115 VPYTEALQVFHHPVAQTPLHEKPYLPPPV 1143 EAL P + P P P V Sbjct: 538 QIKEEALDDAEEPESPPPPPRSPSPEPTV 566 Score = 38.1 bits (87), Expect = 0.11 Identities = 42/150 (28%), Positives = 53/150 (35%), Gaps = 25/150 (16%) Query: 30 SVSSSVPYPGSGTAATQESPAQELLAPQP--FPGPSSVLREGSQEKTGQQQKPPKRP--- 84 S S S+P P + + S Q++L QP P+ V S G Q P P Sbjct: 156 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS 215 Query: 85 ----PIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHP 140 P + S SQ P P P +P H+ + + P RP P HP Sbjct: 216 ATAVPPQGSPTASQAPNQPQAPT--APVPHTHIQQAPA---LHPQRPPSPHPPPHPSPHP 270 Query: 141 QSQLL---------PSHASIIPPEDLPGVP 161 Q L PSHA PP G P Sbjct: 271 PLQPLTGSAGQPSAPSHAQ--PPLHGQGPP 298 Score = 32.7 bits (73), Expect = 4.4 Identities = 43/144 (29%), Positives = 50/144 (34%), Gaps = 32/144 (22%) Query: 29 TSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEA 88 T +++VP GS TA+ + Q AP P T QQ P P Sbjct: 213 TPSATAVPPQGSPTASQAPNQPQAPTAPVP--------------HTHIQQAPALHP---- 254 Query: 89 SVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSH 148 Q P P P SP P L GS Q P P S P LH Q P Sbjct: 255 -----QRPPSPHPPPHPSPHPPLQPLTGSAGQ---PSAP----SHAQPPLHGQGPPGPHS 302 Query: 149 ASIIPPEDLPGVPKVF--VPRPSQ 170 P PG P+ F P+ SQ Sbjct: 303 LQAGPLLQHPGPPQPFGLPPQASQ 326 Score = 32.3 bits (72), Expect = 5.8 Identities = 50/213 (23%), Positives = 74/213 (34%), Gaps = 21/213 (9%) Query: 2200 QMVQARPGA--HPT-LLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPV 2256 QM+QA+P A PT + P P++A G L P S +AS +P Sbjct: 178 QMLQAQPPALQAPTGVTPAPSSA-----PPGTPQLPTPGPTPSATAVPPQGSPTASQAPN 232 Query: 2257 AKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHG-----TGAPAEPT-PTHSPCTP 2310 + P + P PP +PH TG+ +P+ P+H+ Sbjct: 233 QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQ--- 289 Query: 2311 PDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRN 2370 P + P G + Q+ P L+ P P +P PP +A +P + Sbjct: 290 PPLHGQGPPGPHSLQA-GPLLQHPGPP---QPFGLPPQASQGQAPLGTSPAAAYPHTSLQ 345 Query: 2371 LSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPP 2403 L Q P P A P + PP Sbjct: 346 LPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 378 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 67.0 bits (162), Expect = 2e-10 Identities = 135/596 (22%), Positives = 190/596 (31%), Gaps = 100/596 (16%) Query: 755 KSPAEPS-KSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSF------- 806 K PA P ++ P E +P S S + + T K ++ +S Sbjct: 590 KQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKR 649 Query: 807 --EKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEP 864 EK S + + K Q S P +P S + V P+ + + Sbjct: 650 QREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDI---DQ 706 Query: 865 DRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFES 924 D T P P + +++ Q+ AQ PA + P + SS Sbjct: 707 DNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT----------GVTPAPSSAPP 756 Query: 925 SVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPS-PSSDMRPKPLGTHMLTVPSHHP 983 P +P + + S + ++AP+ P + P P TH+ P+ HP Sbjct: 757 GTPQLPTPGPTPSATAVPPQGSPT-------ASQAPNQPQAPTAPVP-HTHIQQAPALHP 808 Query: 984 HAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKC 1043 SP H T S PSAP+ PP P Sbjct: 809 QRPPSPHPPPHPSP---HPPLQPLTGSAG---------QPSAPSHAQPPLHGQGPPGPHS 856 Query: 1044 F----LVRQAS----LSRPPESELEVAPKGRQESEE-PQPSSSKPSAKSSLSQISSAATS 1094 L++ PP++ AP G + P S P+++S+L Q Sbjct: 857 LQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL-QSQQPPRE 915 Query: 1095 HGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHP---VAQTPLHEKPYLPPPVSLFSFQHL 1151 PP +PP +P A Q HP +P LPPP +L L Sbjct: 916 QPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 975 Query: 1152 -VQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMP 1210 H P P S L S P PP L Q+ LP P P LH Q+ P Sbjct: 976 STHHPPSAHPPPLQLMPQSQPLP---SSPAQPPGLTQSQNLPPPPASHPPTGLH--QVAP 1030 Query: 1211 HPANIPFRQ-------PPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKT 1263 P PF Q PP P P++S +G PG T Sbjct: 1031 QP---PFAQHPFVPGGPPPITPPTCPSTSTPPAG-------------PG----------T 1064 Query: 1264 SLAPLATGSAGLSPSTEYSSDIRLPPVAPPA----SSSAPTSAPPLALPACPDTMV 1315 S P +G+A S S LP V + P S PP P+ V Sbjct: 1065 SAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTV 1120 Score = 54.3 bits (129), Expect = 1e-06 Identities = 133/588 (22%), Positives = 193/588 (32%), Gaps = 129/588 (21%) Query: 1792 KTKGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLE 1851 K+ + + S S K Q V + E + TS S+ + E + S+ E Sbjct: 631 KSAKKVKEEASSPLKSNKRQREKVASDTEEADRTS------SKKTKTQEISRPNSPSEGE 684 Query: 1852 DSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSS---PILGPQPP--DAP 1906 SDS DE + + D+ +R +S + P + +DSS +L QPP AP Sbjct: 685 GESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAP 744 Query: 1907 ASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPR 1966 T A S + P LP GP P + GS + + +P Sbjct: 745 TGVTPAP----------------SSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ--APN 786 Query: 1967 RPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQ-ASAPSPPGLHVDPGRGMGALP 2025 +P +P+ P+ H + +PA PQ +P PP P Sbjct: 787 QPQAPT------APVPHTHI---------QQAPALHPQRPPSPHPP-------------P 818 Query: 2026 CGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPP---R 2082 SP L PLT G+ AP +H L G PG P ++ P Sbjct: 819 HPSPHPPLQPLT-GSAGQPSAP-SHAQPPLHGQGPPG-----------PHSLQAGPLLQH 865 Query: 2083 SAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPL-----PHKLLSRSPETCASPWKA 2137 PP + L P A + LG P +P L L S+ P A Sbjct: 866 PGPPQPFGL----PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPA 921 Query: 2138 ESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIG 2197 P P P P+ P H H+ + ++ ++LP P L P+ Sbjct: 922 PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLP--------PPPALKPLS 973 Query: 2198 GIQMVQARPGAHPTLLP-GPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPV 2256 + P AHP L P + + LT ++ P + V Sbjct: 974 SLS-THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP----PPASHPPTGLHQV 1028 Query: 2257 AKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPR 2316 A F + PG PP TP P P+ T +P P T + Sbjct: 1029 APQPPFAQHPFV---------------PGGPPPITP-----PTCPS-TSTPPAGPGTSAQ 1067 Query: 2317 PPQGRRAAQSWS-----------PRLESPRAPTNPEPSATPPLDRSSS 2353 PP AA S +++ EP + PP RS S Sbjct: 1068 PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPS 1115 Score = 42.0 bits (97), Expect = 0.007 Identities = 98/449 (21%), Positives = 149/449 (33%), Gaps = 92/449 (20%) Query: 724 EEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQ-PRTPKPGS 782 + +PPA ++ +P PS A P T P + +VP PT Q P P+ + Sbjct: 735 QAQPPALQAPTGV--TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 792 Query: 783 GSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPH------ 836 + + HT ++Q L + +P + P P P+PH Sbjct: 793 ---------------APVPHT-------HIQQAPALHPQ-RPPSPHPPPHPSPHPPLQPL 829 Query: 837 -GRSAHSLQPKLVRQP----------NIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQ 885 G + P + P ++Q +L P +P P + Sbjct: 830 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP 889 Query: 886 WPQRSQTLAQLPA------EKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESN-V 938 T QLPA + PP+++ L A +A + + +P +P + Sbjct: 890 AAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPP 949 Query: 939 SLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPN 998 LSG S + A P P + L TH PS HP ++ + + Sbjct: 950 HLSGPSPFSM-------NANLPPPPALKPLSSLSTH--HPPSAHPPPLQLMPQSQPLPSS 1000 Query: 999 VSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESE 1058 + +T+ S +L P A P +VAP +PP ++ Sbjct: 1001 PAQPPGLTQ---------SQNLPPPPASHPPTGLHQVAP---------------QPPFAQ 1036 Query: 1059 LEVAPKGRQESEEPQ-PSSSKPSA---KSSLSQISSAATSHGGPPGGKGPGQDRPPLGPT 1114 P G P PS+S P A S+ S AA S G GG PL Sbjct: 1037 HPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTV 1091 Query: 1115 VPYTEALQVFHHPVAQTPLHEKPYLPPPV 1143 EAL P + P P P V Sbjct: 1092 QIKEEALDDAEEPESPPPPPRSPSPEPTV 1120 Score = 38.1 bits (87), Expect = 0.11 Identities = 42/150 (28%), Positives = 53/150 (35%), Gaps = 25/150 (16%) Query: 30 SVSSSVPYPGSGTAATQESPAQELLAPQP--FPGPSSVLREGSQEKTGQQQKPPKRP--- 84 S S S+P P + + S Q++L QP P+ V S G Q P P Sbjct: 710 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS 769 Query: 85 ----PIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHP 140 P + S SQ P P P +P H+ + + P RP P HP Sbjct: 770 ATAVPPQGSPTASQAPNQPQAPT--APVPHTHIQQAPA---LHPQRPPSPHPPPHPSPHP 824 Query: 141 QSQLL---------PSHASIIPPEDLPGVP 161 Q L PSHA PP G P Sbjct: 825 PLQPLTGSAGQPSAPSHAQ--PPLHGQGPP 852 Score = 32.7 bits (73), Expect = 4.4 Identities = 43/144 (29%), Positives = 50/144 (34%), Gaps = 32/144 (22%) Query: 29 TSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEA 88 T +++VP GS TA+ + Q AP P T QQ P P Sbjct: 767 TPSATAVPPQGSPTASQAPNQPQAPTAPVP--------------HTHIQQAPALHP---- 808 Query: 89 SVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSH 148 Q P P P SP P L GS Q P P S P LH Q P Sbjct: 809 -----QRPPSPHPPPHPSPHPPLQPLTGSAGQ---PSAP----SHAQPPLHGQGPPGPHS 856 Query: 149 ASIIPPEDLPGVPKVF--VPRPSQ 170 P PG P+ F P+ SQ Sbjct: 857 LQAGPLLQHPGPPQPFGLPPQASQ 880 Score = 32.3 bits (72), Expect = 5.8 Identities = 50/213 (23%), Positives = 74/213 (34%), Gaps = 21/213 (9%) Query: 2200 QMVQARPGA--HPT-LLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPV 2256 QM+QA+P A PT + P P++A G L P S +AS +P Sbjct: 732 QMLQAQPPALQAPTGVTPAPSSA-----PPGTPQLPTPGPTPSATAVPPQGSPTASQAPN 786 Query: 2257 AKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHG-----TGAPAEPT-PTHSPCTP 2310 + P + P PP +PH TG+ +P+ P+H+ Sbjct: 787 QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQ--- 843 Query: 2311 PDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRN 2370 P + P G + Q+ P L+ P P +P PP +A +P + Sbjct: 844 PPLHGQGPPGPHSLQA-GPLLQHPGPP---QPFGLPPQASQGQAPLGTSPAAAYPHTSLQ 899 Query: 2371 LSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPP 2403 L Q P P A P + PP Sbjct: 900 LPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 932 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 67.0 bits (162), Expect = 2e-10 Identities = 135/596 (22%), Positives = 190/596 (31%), Gaps = 100/596 (16%) Query: 755 KSPAEPS-KSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSF------- 806 K PA P ++ P E +P S S + + T K ++ +S Sbjct: 590 KQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKR 649 Query: 807 --EKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEP 864 EK S + + K Q S P +P S + V P+ + + Sbjct: 650 QREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDI---DQ 706 Query: 865 DRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFES 924 D T P P + +++ Q+ AQ PA + P + SS Sbjct: 707 DNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT----------GVTPAPSSAPP 756 Query: 925 SVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPS-PSSDMRPKPLGTHMLTVPSHHP 983 P +P + + S + ++AP+ P + P P TH+ P+ HP Sbjct: 757 GTPQLPTPGPTPSATAVPPQGSPT-------ASQAPNQPQAPTAPVP-HTHIQQAPALHP 808 Query: 984 HAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKC 1043 SP H T S PSAP+ PP P Sbjct: 809 QRPPSPHPPPHPSP---HPPLQPLTGSAG---------QPSAPSHAQPPLHGQGPPGPHS 856 Query: 1044 F----LVRQAS----LSRPPESELEVAPKGRQESEE-PQPSSSKPSAKSSLSQISSAATS 1094 L++ PP++ AP G + P S P+++S+L Q Sbjct: 857 LQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL-QSQQPPRE 915 Query: 1095 HGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHP---VAQTPLHEKPYLPPPVSLFSFQHL 1151 PP +PP +P A Q HP +P LPPP +L L Sbjct: 916 QPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 975 Query: 1152 -VQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMP 1210 H P P S L S P PP L Q+ LP P P LH Q+ P Sbjct: 976 STHHPPSAHPPPLQLMPQSQPLP---SSPAQPPGLTQSQNLPPPPASHPPTGLH--QVAP 1030 Query: 1211 HPANIPFRQ-------PPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKT 1263 P PF Q PP P P++S +G PG T Sbjct: 1031 QP---PFAQHPFVPGGPPPITPPTCPSTSTPPAG-------------PG----------T 1064 Query: 1264 SLAPLATGSAGLSPSTEYSSDIRLPPVAPPA----SSSAPTSAPPLALPACPDTMV 1315 S P +G+A S S LP V + P S PP P+ V Sbjct: 1065 SAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTV 1120 Score = 54.3 bits (129), Expect = 1e-06 Identities = 133/588 (22%), Positives = 193/588 (32%), Gaps = 129/588 (21%) Query: 1792 KTKGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLE 1851 K+ + + S S K Q V + E + TS S+ + E + S+ E Sbjct: 631 KSAKKVKEEASSPLKSNKRQREKVASDTEEADRTS------SKKTKTQEISRPNSPSEGE 684 Query: 1852 DSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSS---PILGPQPP--DAP 1906 SDS DE + + D+ +R +S + P + +DSS +L QPP AP Sbjct: 685 GESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAP 744 Query: 1907 ASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPR 1966 T A S + P LP GP P + GS + + +P Sbjct: 745 TGVTPAP----------------SSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ--APN 786 Query: 1967 RPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQ-ASAPSPPGLHVDPGRGMGALP 2025 +P +P+ P+ H + +PA PQ +P PP P Sbjct: 787 QPQAPT------APVPHTHI---------QQAPALHPQRPPSPHPP-------------P 818 Query: 2026 CGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPP---R 2082 SP L PLT G+ AP +H L G PG P ++ P Sbjct: 819 HPSPHPPLQPLT-GSAGQPSAP-SHAQPPLHGQGPPG-----------PHSLQAGPLLQH 865 Query: 2083 SAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPL-----PHKLLSRSPETCASPWKA 2137 PP + L P A + LG P +P L L S+ P A Sbjct: 866 PGPPQPFGL----PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPA 921 Query: 2138 ESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIG 2197 P P P P+ P H H+ + ++ ++LP P L P+ Sbjct: 922 PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLP--------PPPALKPLS 973 Query: 2198 GIQMVQARPGAHPTLLP-GPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPV 2256 + P AHP L P + + LT ++ P + V Sbjct: 974 SLS-THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP----PPASHPPTGLHQV 1028 Query: 2257 AKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPR 2316 A F + PG PP TP P P+ T +P P T + Sbjct: 1029 APQPPFAQHPFV---------------PGGPPPITP-----PTCPS-TSTPPAGPGTSAQ 1067 Query: 2317 PPQGRRAAQSWS-----------PRLESPRAPTNPEPSATPPLDRSSS 2353 PP AA S +++ EP + PP RS S Sbjct: 1068 PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPS 1115 Score = 42.0 bits (97), Expect = 0.007 Identities = 98/449 (21%), Positives = 149/449 (33%), Gaps = 92/449 (20%) Query: 724 EEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQ-PRTPKPGS 782 + +PPA ++ +P PS A P T P + +VP PT Q P P+ + Sbjct: 735 QAQPPALQAPTGV--TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 792 Query: 783 GSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPH------ 836 + + HT ++Q L + +P + P P P+PH Sbjct: 793 ---------------APVPHT-------HIQQAPALHPQ-RPPSPHPPPHPSPHPPLQPL 829 Query: 837 -GRSAHSLQPKLVRQP----------NIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQ 885 G + P + P ++Q +L P +P P + Sbjct: 830 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP 889 Query: 886 WPQRSQTLAQLPA------EKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESN-V 938 T QLPA + PP+++ L A +A + + +P +P + Sbjct: 890 AAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPP 949 Query: 939 SLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPN 998 LSG S + A P P + L TH PS HP ++ + + Sbjct: 950 HLSGPSPFSM-------NANLPPPPALKPLSSLSTH--HPPSAHPPPLQLMPQSQPLPSS 1000 Query: 999 VSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESE 1058 + +T+ S +L P A P +VAP +PP ++ Sbjct: 1001 PAQPPGLTQ---------SQNLPPPPASHPPTGLHQVAP---------------QPPFAQ 1036 Query: 1059 LEVAPKGRQESEEPQ-PSSSKPSA---KSSLSQISSAATSHGGPPGGKGPGQDRPPLGPT 1114 P G P PS+S P A S+ S AA S G GG PL Sbjct: 1037 HPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTV 1091 Query: 1115 VPYTEALQVFHHPVAQTPLHEKPYLPPPV 1143 EAL P + P P P V Sbjct: 1092 QIKEEALDDAEEPESPPPPPRSPSPEPTV 1120 Score = 38.1 bits (87), Expect = 0.11 Identities = 42/150 (28%), Positives = 53/150 (35%), Gaps = 25/150 (16%) Query: 30 SVSSSVPYPGSGTAATQESPAQELLAPQP--FPGPSSVLREGSQEKTGQQQKPPKRP--- 84 S S S+P P + + S Q++L QP P+ V S G Q P P Sbjct: 710 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS 769 Query: 85 ----PIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHP 140 P + S SQ P P P +P H+ + + P RP P HP Sbjct: 770 ATAVPPQGSPTASQAPNQPQAPT--APVPHTHIQQAPA---LHPQRPPSPHPPPHPSPHP 824 Query: 141 QSQLL---------PSHASIIPPEDLPGVP 161 Q L PSHA PP G P Sbjct: 825 PLQPLTGSAGQPSAPSHAQ--PPLHGQGPP 852 Score = 32.7 bits (73), Expect = 4.4 Identities = 43/144 (29%), Positives = 50/144 (34%), Gaps = 32/144 (22%) Query: 29 TSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEA 88 T +++VP GS TA+ + Q AP P T QQ P P Sbjct: 767 TPSATAVPPQGSPTASQAPNQPQAPTAPVP--------------HTHIQQAPALHP---- 808 Query: 89 SVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSH 148 Q P P P SP P L GS Q P P S P LH Q P Sbjct: 809 -----QRPPSPHPPPHPSPHPPLQPLTGSAGQ---PSAP----SHAQPPLHGQGPPGPHS 856 Query: 149 ASIIPPEDLPGVPKVF--VPRPSQ 170 P PG P+ F P+ SQ Sbjct: 857 LQAGPLLQHPGPPQPFGLPPQASQ 880 Score = 32.3 bits (72), Expect = 5.8 Identities = 50/213 (23%), Positives = 74/213 (34%), Gaps = 21/213 (9%) Query: 2200 QMVQARPGA--HPT-LLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPV 2256 QM+QA+P A PT + P P++A G L P S +AS +P Sbjct: 732 QMLQAQPPALQAPTGVTPAPSSA-----PPGTPQLPTPGPTPSATAVPPQGSPTASQAPN 786 Query: 2257 AKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHG-----TGAPAEPT-PTHSPCTP 2310 + P + P PP +PH TG+ +P+ P+H+ Sbjct: 787 QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQ--- 843 Query: 2311 PDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRN 2370 P + P G + Q+ P L+ P P +P PP +A +P + Sbjct: 844 PPLHGQGPPGPHSLQA-GPLLQHPGPP---QPFGLPPQASQGQAPLGTSPAAAYPHTSLQ 899 Query: 2371 LSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPP 2403 L Q P P A P + PP Sbjct: 900 LPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 932 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.308 0.127 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 126,604,795 Number of Sequences: 37866 Number of extensions: 8256035 Number of successful extensions: 99271 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1316 Number of HSP's successfully gapped in prelim test: 2203 Number of HSP's that attempted gapping in prelim test: 39006 Number of HSP's gapped (non-prelim): 53945 length of query: 2405 length of database: 18,247,518 effective HSP length: 119 effective length of query: 2286 effective length of database: 13,741,464 effective search space: 31412986704 effective search space used: 31412986704 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.