Guide to the Human Genome
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Search of human proteins with 189181750

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189181750 human immunodeficiency virus type I enhancer
binding protein 3 b [Homo sapiens]
         (2405 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189181750 human immunodeficiency virus type I enhancer bindin...  4893   0.0  
gi|116089331 human immunodeficiency virus type I enhancer bindin...  4888   0.0  
gi|110347463 human immunodeficiency virus type I enhancer bindin...  1042   0.0  
gi|116805342 human immunodeficiency virus type I enhancer bindin...   721   0.0  
gi|123701326 zinc finger protein 831 [Homo sapiens]                   171   1e-41
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...   106   2e-22
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    88   9e-17
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    86   4e-16
gi|163965366 nascent polypeptide-associated complex alpha subuni...    80   2e-14
gi|49087132 sal-like 2 [Homo sapiens]                                  79   7e-14
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        75   6e-13
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    74   2e-12
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    74   2e-12
gi|154146199 sal-like 3 [Homo sapiens]                                 73   4e-12
gi|150170670 piccolo isoform 2 [Homo sapiens]                          71   1e-11
gi|150378539 piccolo isoform 1 [Homo sapiens]                          71   1e-11
gi|189217876 sal-like 1 isoform b [Homo sapiens]                       71   1e-11
gi|118442837 sal-like 1 isoform a [Homo sapiens]                       71   1e-11
gi|40807465 zinc finger protein 341 [Homo sapiens]                     71   1e-11
gi|221139761 zinc finger protein 853 [Homo sapiens]                    69   4e-11
gi|193082982 zinc finger protein 837 isoform 1 [Homo sapiens]          69   6e-11
gi|193082980 zinc finger protein 837 isoform 2 [Homo sapiens]          69   6e-11
gi|4508009 zinc finger protein 177 [Homo sapiens]                      69   7e-11
gi|138175817 zinc finger protein 236 [Homo sapiens]                    68   1e-10
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              67   2e-10
gi|10047144 sal-like 4 [Homo sapiens]                                  67   2e-10
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        67   2e-10
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          67   2e-10
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          67   2e-10
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          67   2e-10

>gi|189181750 human immunodeficiency virus type I enhancer binding
            protein 3 b [Homo sapiens]
          Length = 2405

 Score = 4893 bits (12691), Expect = 0.0
 Identities = 2405/2405 (100%), Positives = 2405/2405 (100%)

Query: 1    MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFP 60
            MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFP
Sbjct: 1    MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFP 60

Query: 61   GPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQ 120
            GPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQ
Sbjct: 61   GPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQ 120

Query: 121  LVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAH 180
            LVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAH
Sbjct: 121  LVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAH 180

Query: 181  KKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRK 240
            KKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRK
Sbjct: 181  KKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRK 240

Query: 241  SHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSP 300
            SHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSP
Sbjct: 241  SHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSP 300

Query: 301  RPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTI 360
            RPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTI
Sbjct: 301  RPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTI 360

Query: 361  KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFG 420
            KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFG
Sbjct: 361  KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFG 420

Query: 421  KCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSE 480
            KCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSE
Sbjct: 421  KCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSE 480

Query: 481  IDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRS 540
            IDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRS
Sbjct: 481  IDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRS 540

Query: 541  HSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGE 600
            HSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGE
Sbjct: 541  HSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGE 600

Query: 601  YSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEA 660
            YSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEA
Sbjct: 601  YSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEA 660

Query: 661  HKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKS 720
            HKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKS
Sbjct: 661  HKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKS 720

Query: 721  LGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKP 780
            LGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKP
Sbjct: 721  LGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKP 780

Query: 781  GSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSA 840
            GSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSA
Sbjct: 781  GSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSA 840

Query: 841  HSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEK 900
            HSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEK
Sbjct: 841  HSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEK 900

Query: 901  LPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAP 960
            LPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAP
Sbjct: 901  LPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAP 960

Query: 961  SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSL 1020
            SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSL
Sbjct: 961  SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSL 1020

Query: 1021 TGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS 1080
            TGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS
Sbjct: 1021 TGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS 1080

Query: 1081 AKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLP 1140
            AKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLP
Sbjct: 1081 AKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLP 1140

Query: 1141 PPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHP 1200
            PPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHP
Sbjct: 1141 PPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHP 1200

Query: 1201 GQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQ 1260
            GQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQ
Sbjct: 1201 GQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQ 1260

Query: 1261 IKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVP 1320
            IKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVP
Sbjct: 1261 IKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVP 1320

Query: 1321 VRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGP 1380
            VRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGP
Sbjct: 1321 VRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGP 1380

Query: 1381 SGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLEL 1440
            SGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLEL
Sbjct: 1381 SGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLEL 1440

Query: 1441 TMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLS 1500
            TMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLS
Sbjct: 1441 TMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLS 1500

Query: 1501 SLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQP 1560
            SLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQP
Sbjct: 1501 SLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQP 1560

Query: 1561 DLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHA 1620
            DLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHA
Sbjct: 1561 DLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHA 1620

Query: 1621 DRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSS 1680
            DRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSS
Sbjct: 1621 DRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSS 1680

Query: 1681 RKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSN 1740
            RKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSN
Sbjct: 1681 RKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSN 1740

Query: 1741 EEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800
            EEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH
Sbjct: 1741 EEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800

Query: 1801 MKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLD 1860
            MKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLD
Sbjct: 1801 MKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLD 1860

Query: 1861 EDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSE 1920
            EDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSE
Sbjct: 1861 EDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSE 1920

Query: 1921 AERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPP 1980
            AERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPP
Sbjct: 1921 AERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPP 1980

Query: 1981 LARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCP 2040
            LARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCP
Sbjct: 1981 LARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCP 2040

Query: 2041 LGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAG 2100
            LGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAG
Sbjct: 2041 LGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAG 2100

Query: 2101 EHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSAL 2160
            EHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSAL
Sbjct: 2101 EHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSAL 2160

Query: 2161 HDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAW 2220
            HDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAW
Sbjct: 2161 HDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAW 2220

Query: 2221 VSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERT 2280
            VSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERT
Sbjct: 2221 VSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERT 2280

Query: 2281 GGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNP 2340
            GGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNP
Sbjct: 2281 GGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNP 2340

Query: 2341 EPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDR 2400
            EPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDR
Sbjct: 2341 EPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDR 2400

Query: 2401 VPPNA 2405
            VPPNA
Sbjct: 2401 VPPNA 2405


>gi|116089331 human immunodeficiency virus type I enhancer binding
            protein 3 [Homo sapiens]
          Length = 2406

 Score = 4888 bits (12679), Expect = 0.0
 Identities = 2405/2406 (99%), Positives = 2405/2406 (99%), Gaps = 1/2406 (0%)

Query: 1    MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFP 60
            MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFP
Sbjct: 1    MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFP 60

Query: 61   GPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQ 120
            GPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQ
Sbjct: 61   GPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQ 120

Query: 121  LVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAH 180
            LVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAH
Sbjct: 121  LVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAH 180

Query: 181  KKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRK 240
            KKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRK
Sbjct: 181  KKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRK 240

Query: 241  SHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSP 300
            SHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSP
Sbjct: 241  SHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSP 300

Query: 301  RPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTI 360
            RPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTI
Sbjct: 301  RPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTI 360

Query: 361  KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFG 420
            KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFG
Sbjct: 361  KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFG 420

Query: 421  KCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSE 480
            KCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSE
Sbjct: 421  KCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSE 480

Query: 481  IDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRS 540
            IDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRS
Sbjct: 481  IDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRS 540

Query: 541  HSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGE 600
            HSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGE
Sbjct: 541  HSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGE 600

Query: 601  YSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEA 660
            YSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEA
Sbjct: 601  YSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEA 660

Query: 661  HKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKS 720
            HKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKS
Sbjct: 661  HKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKS 720

Query: 721  LGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKP 780
            LGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKP
Sbjct: 721  LGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKP 780

Query: 781  GSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSA 840
            GSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSA
Sbjct: 781  GSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSA 840

Query: 841  HSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEK 900
            HSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEK
Sbjct: 841  HSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEK 900

Query: 901  LPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAP 960
            LPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAP
Sbjct: 901  LPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAP 960

Query: 961  SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSL 1020
            SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSL
Sbjct: 961  SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSL 1020

Query: 1021 TGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS 1080
            TGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS
Sbjct: 1021 TGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS 1080

Query: 1081 AKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLP 1140
            AKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLP
Sbjct: 1081 AKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLP 1140

Query: 1141 PPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHP 1200
            PPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHP
Sbjct: 1141 PPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHP 1200

Query: 1201 GQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQ 1260
            GQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQ
Sbjct: 1201 GQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQ 1260

Query: 1261 IKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVP 1320
            IKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVP
Sbjct: 1261 IKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVP 1320

Query: 1321 VRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGP 1380
            VRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGP
Sbjct: 1321 VRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGP 1380

Query: 1381 SGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLEL 1440
            SGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLEL
Sbjct: 1381 SGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLEL 1440

Query: 1441 TMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLS 1500
            TMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLS
Sbjct: 1441 TMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLS 1500

Query: 1501 SLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQP 1560
            SLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQP
Sbjct: 1501 SLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQP 1560

Query: 1561 DLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHA 1620
            DLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHA
Sbjct: 1561 DLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHA 1620

Query: 1621 DRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSS 1680
            DRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSS
Sbjct: 1621 DRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSS 1680

Query: 1681 RKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSN 1740
            RKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSN
Sbjct: 1681 RKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSN 1740

Query: 1741 EEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800
            EEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH
Sbjct: 1741 EEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800

Query: 1801 MKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLD 1860
            MKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLD
Sbjct: 1801 MKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLD 1860

Query: 1861 EDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSE 1920
            EDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSE
Sbjct: 1861 EDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSE 1920

Query: 1921 AERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPP 1980
            AERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPP
Sbjct: 1921 AERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPP 1980

Query: 1981 LARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCP 2040
            LARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCP
Sbjct: 1981 LARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCP 2040

Query: 2041 LGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAG 2100
            LGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAG
Sbjct: 2041 LGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAG 2100

Query: 2101 EHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPW-KAESRSPSCSPGPAHPLSSRPFSA 2159
            EHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPW KAESRSPSCSPGPAHPLSSRPFSA
Sbjct: 2101 EHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQKAESRSPSCSPGPAHPLSSRPFSA 2160

Query: 2160 LHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAA 2219
            LHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAA
Sbjct: 2161 LHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAA 2220

Query: 2220 WVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERER 2279
            WVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERER
Sbjct: 2221 WVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERER 2280

Query: 2280 TGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTN 2339
            TGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTN
Sbjct: 2281 TGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTN 2340

Query: 2340 PEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPED 2399
            PEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPED
Sbjct: 2341 PEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPED 2400

Query: 2400 RVPPNA 2405
            RVPPNA
Sbjct: 2401 RVPPNA 2406


>gi|110347463 human immunodeficiency virus type I enhancer binding
            protein 2 [Homo sapiens]
          Length = 2446

 Score = 1042 bits (2695), Expect = 0.0
 Identities = 864/2362 (36%), Positives = 1132/2362 (47%), Gaps = 367/2362 (15%)

Query: 52   ELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPE 111
            +L        PS V+++       ++Q PP RP   +  H    PQH L    M   KP 
Sbjct: 62   QLFGSGKLASPSEVVQQ-----VAEKQYPPHRPSPYSCQHSLSFPQHSLPQGVMHSTKPH 116

Query: 112  HLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQV 171
              LEG  W     + PGP  S  +  L P    +  H+   P + +  +   +  + SQ 
Sbjct: 117  QSLEGPPW-----LFPGPLPSVASEDLFPFP--IHGHSGGYPRKKISSLNPAY-SQYSQK 168

Query: 172  SLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKT 231
            S++  EEAHKKE KP+KPGKYIC YCSR CAKPSVL+KHIRSHTGERPYPC PCGFSFKT
Sbjct: 169  SIEQAEEAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKT 228

Query: 232  KSNLYKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSAT 291
            KSNLYKHRKSHAH IKAGL       +    LE   I  E        +STD++EE+S  
Sbjct: 229  KSNLYKHRKSHAHAIKAGLVPFTESAVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLF 288

Query: 292  SGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPP---PFVEPSSEH 348
            +    ++SP P  PL    + S G +  S E  SL        L  P    P    SS++
Sbjct: 289  AEASDKMSPGPPIPL---DIASRGGYHGSLEE-SLGGPMKVPILIIPKSGIPLPNESSQY 344

Query: 349  ---------PLSHKPEDTHTIKQKLALRLSERKKVIDEQAF--LSPGSKGSTESGYFSRS 397
                      L+ K +D+HT+KQKLALRLSE+K    E +   LSP SKGST+SGYFSRS
Sbjct: 345  IGPDMLPNPSLNTKADDSHTVKQKLALRLSEKKGQDSEPSLNLLSPHSKGSTDSGYFSRS 404

Query: 398  ESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVP 457
            ESAEQQ+SPPNTNAKSY EIIFGK  R+  R A+   T++Q    +  +     +P    
Sbjct: 405  ESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNALSVTTTSQERAAMGRKGIMEPLPHVNT 464

Query: 458  RTQV--IEHITKLITINEAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLYREPL-SSHSE 514
            R  V   E     +  ++  VD S+   +K  + +   R     P S      L  ++ +
Sbjct: 465  RLDVKMFEDPVSQLIPSKGDVDPSQTSMLKSTKFNSESRQPQIIPSSIRNEGKLYPANFQ 524

Query: 515  KTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALS 574
             + P    + L+ P  ++P   L+RS+S+P+++ T  T     RGS+SFD+ +T S+ + 
Sbjct: 525  GSNP----VLLEAPVDSSP---LIRSNSVPTSSATNLTIPPSLRGSHSFDERMTGSDDVF 577

Query: 575  HSSHVFTSHPRMLKRQPAIELPL--GGEYSSEEPGPSSKDTASKPSDEVEPKESELTKKT 632
            +   V     RML+RQ A ELP    G    E  G   K  +S        KE +L+   
Sbjct: 578  YPGTVGIPPQRMLRRQAAFELPSVQEGHVEVEHHGRMLKGISSSSL-----KEKKLSPGD 632

Query: 633  KKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEH 692
            + G       Y+ ++C   YKK ++ E  K+ Y       + IS  +      E      
Sbjct: 633  RVG-------YDYDVCRKPYKKWEDSETPKQNY-------RDISCLSSLKHGGEYFMDPV 678

Query: 693  EPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAF---------------------- 730
             P  Q +    GTT E    RKRRKEKS+GDEE+ P                        
Sbjct: 679  VPL-QGVPSMFGTTCEN---RKRRKEKSVGDEEDTPMICSSIVSTPVGIMASDYDPKLQM 734

Query: 731  -ESTKSQFGSPGPSDAA-----RNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGS 784
             E  +S F   G  + +     R  P      P  PS  + S E P+           G 
Sbjct: 735  QEGVRSGFAMAGHENLSHGHTERFDPCRPQLQPGSPS--LVSEESPSAIDSDKMSDLGG- 791

Query: 785  ESGKERRTTSKEISVIQHTSS------FEKSDSLE--------QPSGLEGEDKPLAQFP- 829
                 R+     ISVIQHT+S      FE+S+S E         PS  E  D  +++ P 
Sbjct: 792  -----RKPPGNVISVIQHTNSLSRPNSFERSESAELVACTQDKAPSPSETCDSEISEAPV 846

Query: 830  SPPPAPHGRSAHS----------------LQPKLVRQPNIQVPEILVTEEPDRPDTEPEP 873
            SP  AP G  A S                 QP+LVRQ NIQVPEI VTEEPD+P+ E E 
Sbjct: 847  SPEWAPPGDGAESGGKPSPSQQVQQQSYHTQPRLVRQHNIQVPEIRVTEEPDKPEKEKEA 906

Query: 874  PPKEPEK-TEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESS-VPLSRS 931
              KEPEK  EEFQWPQRS+TL+QLPAEKLPPKKKRLRLA+M  SSGESSFES+   LSRS
Sbjct: 907  QSKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTGTGLSRS 966

Query: 932  PSQESNVSLSGSSRSASFERDDHGKAEAPSPS------SDMRPKPLGTHMLTVPSHHPHA 985
            PSQESN+S S SS S SFER++  K  A          S+    P G++ L+VP HH H 
Sbjct: 967  PSQESNLSHS-SSFSMSFEREETSKLSALPKQDEFGKHSEFLTVPAGSYSLSVPGHH-HQ 1024

Query: 986  REMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPP-ERRKCF 1044
            +EMRR +SEQ P   H A + E RSKSFDYG+LS     AP   A  + V+P  ER+KCF
Sbjct: 1025 KEMRRCSSEQMP-CPHPAEVPEVRSKSFDYGNLS----HAPVSGAAASTVSPSRERKKCF 1079

Query: 1045 LVRQASLSRPPE-SELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATS--HGGPPGG 1101
            LVRQAS S  PE S+ EV      + E+             L  + +   S  H GPP  
Sbjct: 1080 LVRQASFSGSPEISQGEVGMDQSVKQEQ-------------LEHLHAGLRSGWHHGPPAV 1126

Query: 1102 KGPGQDRPP----LGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPG 1157
              P Q   P     GP  P +             PLH    L  P       H+   E  
Sbjct: 1127 LPPLQQEDPGKQVAGPCPPLSSG-----------PLH----LAQP----QIMHMDSQESL 1167

Query: 1158 QSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPF 1217
            ++P    T  M+S       +P  P        +P  P      Q   P +     ++P 
Sbjct: 1168 RNPLIQPTSYMTSK-----HLPEQPHLFPHQETIPFSPIQNALFQFQYPTVCM--VHLPA 1220

Query: 1218 RQPP---SFLPMPY---PTSSALSSGFFLPLQSQFALQLPGDVESHLP----QIKTSLAP 1267
            +QPP   +  P P+   P  S     F   + S + L+   +     P      K    P
Sbjct: 1221 QQPPWWQAHFPHPFAQHPQKSYGKPSFQTEIHSSYPLEHVAEHTGKKPAEYAHTKEQTYP 1280

Query: 1268 LATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPP---------LALPACPDTMVSLV 1318
              +G++GL P         L P  P   SS  T  P           A      ++   V
Sbjct: 1281 CYSGASGLHPKN-------LLPKFPSDQSSKSTETPSEQVLQEDFASANAGSLQSLPGTV 1333

Query: 1319 VPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGP 1378
            VPVR+QT++PSYGS MYT++SQIL    Q S A V + K +E  ++ T V  A +  +G 
Sbjct: 1334 VPVRIQTHVPSYGSVMYTSISQIL---GQNSPAIV-ICKVDENMTQRTLVTNAAMQGIGF 1389

Query: 1379 GPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSL 1438
              + +  + +     P  + P TLP    +S+    + S   S +T GGSKR+LSPA SL
Sbjct: 1390 NIAQVLGQHAGLEKYPIWKAPQTLPLGLESSIPL-CLPSTSDSVATLGGSKRMLSPASSL 1448

Query: 1439 ELTMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGK----RPEKSHLGNQGQGRR 1494
            EL MET+QQKRVKEE+        ++V+  S V  +  D K    RP+K  L  QG    
Sbjct: 1449 ELFMETKQQKRVKEEKMYG-----QIVEELSAVELTNSDIKKDLSRPQKPQLVRQGCASE 1503

Query: 1495 ELEMLSSLSSD-----PSDTKEIPPLPHPALSHGTAPGSEALK--EYPQPSGKPHRRGLT 1547
              + L S SS      PS +++ P +  P+      P  E L     P P  K      +
Sbjct: 1504 PKDGLQSGSSSFSSLSPSSSQDYPSVS-PSSREPFLPSKEMLSGSRAPLPGQKSSGPSES 1562

Query: 1548 PLSVKKEDSKEQPDLPSLAPPSS-LPLSETSS---------------RPAKSQEGT---- 1587
              S  + D  E     S++P SS LP  +                  R A +  G     
Sbjct: 1563 KESSDELDIDETASDMSMSPQSSSLPAGDGQLEEEGKGHKRPVGMLVRMASAPSGNVADS 1622

Query: 1588 --------DSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNL 1639
                    D +++LQFPSL TTT VSWC+LNY KPN++Q A  +SSVYA WCIS  NPN 
Sbjct: 1623 TLLLTDMADFQQILQFPSLRTTTTVSWCFLNYTKPNYVQQATFKSSVYASWCISSCNPNP 1682

Query: 1640 PGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPS--LVSPE 1697
             G++TK  L+LLRSKQK++ E YT+A    P  G+L  SS+ K + T++   +  L   +
Sbjct: 1683 SGLNTKTTLALLRSKQKITAEIYTLAAMHRPGTGKLTSSSAWK-QFTQMKPDASFLFGSK 1741

Query: 1698 GQKDLARVEKEEERRGEPEEDAP-ASQRGEPARIKIFEGGYKSNEEYVYVRGRGRGKYVC 1756
             ++ L     +E  +G+   D    S++ EP RIKIFEGGYKSNE+YVYVRGRGRGKY+C
Sbjct: 1742 LERKLVGNILKERGKGDIHGDKDIGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYIC 1801

Query: 1757 EECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQETGV- 1815
            EECGIRCKKPSMLKKHIRTHTDVRPYVCK C+FAFKTKGNLTKHMKSKAH KKC E GV 
Sbjct: 1802 EECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVS 1861

Query: 1816 ---LEELEAEEGTS-DDLFQDSEGREGSEAVEEHQFSDLEDSDS---DSDLDEDEDEDEE 1868
               +++ E EE  + +DL + +E    S    +HQFSD E+SD    D + D+DEDED+ 
Sbjct: 1862 MTSVDDTETEEAENLEDLHKAAEKHSMSSISTDHQFSDAEESDGEDGDDNDDDDEDEDDF 1921

Query: 1869 ESQDELS-RPSSEAPPPGPPHALRADSSPI-LGPQPPDAPASG----------------- 1909
            + Q +L+ +  S +  P PP   R  S P+ +G  P   P+                   
Sbjct: 1922 DDQGDLTPKTRSRSTSPQPP---RFSSLPVNVGAVPHGVPSDSSLGHSSLISYLVTLPSI 1978

Query: 1910 --TEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRR 1967
              T+    S   E  ++T       S+S    P      + S   D    L  +P S  R
Sbjct: 1979 RVTQLMTPSDSCEDTQMTEYQRLFQSKSTDSEPDKDRLDIPSC-MDEECMLPSEPSSSPR 2037

Query: 1968 PWSPSKEAGSRPPLARKHSLTKNDSSPQRC-SPAREPQASAPSPPGLHVDPGRGMGALPC 2026
             +SPS            HS    DSSP R  SP R         P  H+ P R +     
Sbjct: 2038 DFSPSSH----------HSSPGYDSSPCRDNSPKRYLIPKGDLSPRRHLSPRRDL----- 2082

Query: 2027 GSPRLQLSPLTLCPLGRELA-----PRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPP 2081
             SP   LSP     L RE++     PR H+               SP R  SPG+  +  
Sbjct: 2083 -SPMRHLSPRKEAALRREMSQRDVSPRRHL---------------SPRRPVSPGKDITAR 2126

Query: 2082 RSAPPGK-----WALAGPGSPSAGEHGPGLGLDPRVLFPPAPL-PHKLLSRSPETCASPW 2135
            R   P +       +  P    A  H P L +   +   P  L P  L    P+      
Sbjct: 2127 RDLSPRRERRYMTTIRAPSPRRALYHNPPLSMGQYLQAEPIVLGPPNLRRGLPQVPYFSL 2186

Query: 2136 KAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIP 2195
              +           HP SS      +D+           +FSHLPLHSQ   RAP P++P
Sbjct: 2187 YGDQEGAY-----EHPGSSLFPEGPNDY-----------VFSHLPLHSQQQVRAPIPMVP 2230

Query: 2196 IGGIQMVQARPGAHPTLLPGPT 2217
            +GGIQMV + P A  +L P PT
Sbjct: 2231 VGGIQMVHSMPPALSSLHPSPT 2252


>gi|116805342 human immunodeficiency virus type I enhancer binding
            protein 1 [Homo sapiens]
          Length = 2718

 Score =  721 bits (1861), Expect = 0.0
 Identities = 685/2116 (32%), Positives = 940/2116 (44%), Gaps = 369/2116 (17%)

Query: 182  KERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKS 241
            K++KP+K GKYIC+YC+R CAKPSVL KHIRSHTGERPYPC  CGFSFKTKSNLYKH+KS
Sbjct: 396  KDQKPKKQGKYICEYCNRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKS 455

Query: 242  HAHRIKAGLA--SGMGGEMYPH----GLEMERIPGEEFEEPTEGESTDSEEETSATSGHP 295
            HAH IK GL      GG    H     L +     +  E   EG + + + +  A    P
Sbjct: 456  HAHTIKLGLVLQPDAGGLFLSHESPKALSIHSDVEDSGESEEEGATDERQHDLGAMELQP 515

Query: 296  AELSPRPK--QPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFV---------EP 344
              +  R    + LL S    S   +   +     +S+ +Q++ + P  V           
Sbjct: 516  VHIIKRMSNAETLLKSSFTPSSPENVIGDFLLQDRSAESQAVTELPKVVVHHVTVSPLRT 575

Query: 345  SSEHPLSHKPEDTHTIKQK---------LALRLSE------------------------- 370
             S   +  KPE +   KQK         L+  +S+                         
Sbjct: 576  DSPKAMDPKPELSSAQKQKDLQVTNVQPLSANMSQGGVSRLETNENSHQKGDMNPLEGKQ 635

Query: 371  ------------RKKVID-----EQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKS 413
                        R++  D     +   LSP S GST+SGYFSRSESA+Q VSPP   A+ 
Sbjct: 636  DSHVGTVHAQLQRQQATDYSQEQQGKLLSPRSLGSTDSGYFSRSESADQTVSPPTPFARR 695

Query: 414  YAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVP---RTQVIEH-ITKLI 469
                     GR    +A L  TST   LP  T +K  L+P  +     T+ +E  I+KLI
Sbjct: 696  LPSTEQDS-GRSNGPSAALVTTSTPSALP--TGEKALLLPGQMRPPLATKTLEERISKLI 752

Query: 470  TINEAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLYREPL-----------SSHSE---- 514
            + NEA+VD  ++DSVKPRR+SLSRR S++SPKS ++++             SS S+    
Sbjct: 753  SDNEALVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPVGRRTSSSSDIPKS 812

Query: 515  ---KTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAA-----CTISTPHHPFRGSYSFDDH 566
                T+  + +  L  P  +   +P+ RS+SMP+         I  P HP RGS SFDD 
Sbjct: 813  PFTPTEKSKQVFLLSVP--SLDCLPITRSNSMPTTGYSAVPANIIPPPHPLRGSQSFDDK 870

Query: 567  I---TDSEALS--HSSHVFTSHPRMLKRQPAIELPLGGEYSSEEPGPS---SKDTASKPS 618
            I    D   +S  ++    + HPR L RQ AIE     E      G S   S        
Sbjct: 871  IGTFYDDVFVSGPNAPVPQSGHPRTLVRQAAIEDSSANESHVLGTGQSLDESHQGCHAAG 930

Query: 619  DEVEPKESELTK----KTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKP 674
            + +  +   L +    + KK  + +G ++EC  C  RY+K +N+E HKK+YCSEL   K 
Sbjct: 931  EAMSVRSKALAQGPHIEKKKSHQGRGTMFECETCRNRYRKLENFENHKKFYCSELHGPKT 990

Query: 675  ISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTT---LELTP-LRKRRKEKSLGDEEEPPAF 730
              A      E E S +      Q++HY++  +    E TP +RKRRK KS+GD+EE    
Sbjct: 991  KVA----MREPEHSPVPGGLQPQILHYRVAGSSGIWEQTPQIRKRRKMKSVGDDEELQQN 1046

Query: 731  ESTKSQFGSPG----------PSDAARNLPLESTKS----PAEPSKSVPSLEGPTGFQPR 776
            ES  S   S G          PS    N+ + S +       + S       GP   Q  
Sbjct: 1047 ESGTSPKSSEGLQFQNALGCNPSLPKHNVTIRSDQQHKNIQLQNSHIHLVARGPE--QTM 1104

Query: 777  TPK--------PGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPS------------ 816
             PK          S ++   E +     ISVIQHT+S  + +S ++P             
Sbjct: 1105 DPKLSTIMEQQISSAAQDKIELQRHGTGISVIQHTNSLSRPNSFDKPEPFERASPVSFQE 1164

Query: 817  -------------GLEGEDKPLAQFPSPP------------------PAPHGRSAHSLQP 845
                         G+  E+   ++  S P                   +P  R       
Sbjct: 1165 LNRTGKSGSLKVIGISQEESHPSRDGSHPHQLALSDALRGELQESSRKSPSERHVLGQPS 1224

Query: 846  KLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKK 905
            +LVRQ NIQVPEILVTEEPDR   + E    + EK+E+F WPQRS+TL++LP EKLPPKK
Sbjct: 1225 RLVRQHNIQVPEILVTEEPDR---DLEAQCHDQEKSEKFSWPQRSETLSKLPTEKLPPKK 1281

Query: 906  KRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSD 965
            KRLRLAE+  SS ESSF+S+  LSRS S+ES++S + SS SAS + +D  K EA SP  D
Sbjct: 1282 KRLRLAEIEHSSTESSFDST--LSRSLSRESSLSHT-SSFSASLDIEDVSKTEA-SPKID 1337

Query: 966  MRPK------PLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLS 1019
               K      P G + L VP  H   REMRR+ASEQ      S  +++ RSKSFD GS++
Sbjct: 1338 FLNKAEFLMIPAGLNTLNVPGCH---REMRRTASEQINCTQTSMEVSDLRSKSFDCGSIT 1394

Query: 1020 ---------LTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELE-VAPKGRQES 1069
                     L  PS+P+ V     V   ERR+  LVRQ SL+  P+S L  V P   Q +
Sbjct: 1395 PPQTTPLTELQPPSSPSRVGVTGHVPLLERRRGPLVRQISLNIAPDSHLSPVHPTSFQNT 1454

Query: 1070 EEPQ----PSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFH 1125
              P     P        +SL++  SA T H               L      + +  VF 
Sbjct: 1455 ALPSVNAVPYQGPQLTSTSLAEF-SANTLHS--------QTQVKDLQAETSNSSSTNVF- 1504

Query: 1126 HPVAQ---TPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLP 1182
             PV Q     L  + + PP            H+  Q     STQ      +S  S     
Sbjct: 1505 -PVQQLCDINLLNQIHAPP-----------SHQSTQLSLQVSTQGSKPDKNSVLSGSSKS 1552

Query: 1183 PSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPL 1242
               F AP   L   V   G    P    +P +     P   +  P  T   ++S      
Sbjct: 1553 EDCF-APKYQLHCQVFTSG----PSCSSNPVH---SLPNQVISDPVGTDHCVTS------ 1598

Query: 1243 QSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSA 1302
             +    +L   + +  P +   L PL  GS      + +   IRL    P    +  TS 
Sbjct: 1599 -ATLPTKLIDSMSNSHPLLPPELRPL--GSQVQKVPSSFMLPIRLQSSVPAYCFATLTSL 1655

Query: 1303 PPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPP 1362
            P +        +V+  +P     N P       T  S + +++ Q S  T+        P
Sbjct: 1656 PQI--------LVTQDLP-----NQP----ICQTNHSVVPISEEQNSVPTLQKGHQNALP 1698

Query: 1363 SKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSS 1422
            +        +V       S LSE            +P+T            S+  L    
Sbjct: 1699 NPEKEFLCENVFSEMSQNSSLSES-----------LPIT---------QKISVGRLSPQQ 1738

Query: 1423 STAGGSKRVLSPAGSLELTMETQQQKRVKEEE--------------ASKADEKLELVKPC 1468
             ++  SKR+LSPA SL++ ME + QKR K+E               +S+ +E  +  KP 
Sbjct: 1739 ESSASSKRMLSPANSLDIAME-KHQKRAKDENGAVCATDVRPLEALSSRVNEASKQKKPI 1797

Query: 1469 ---SVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDT--------KEIPPLPH 1517
                V  T   DG   EK            + + + L +D S T        + I  L  
Sbjct: 1798 LVRQVCTTEPLDGVMLEKDVFSQPEISNEAVNLTNVLPADNSSTGCSKFVVIEPISELQE 1857

Query: 1518 PALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLA-PPSSLPLSET 1576
                  +   +  ++  P PS   H   ++PL  K  D+ ++   P +      + + E 
Sbjct: 1858 FENIKSSTSLTLTVRSSPAPSENTH---ISPL--KCTDNNQERKSPGVKNQGDKVNIQEQ 1912

Query: 1577 SSRPAKSQEGTDSK--KVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISL 1634
            S +P  S    + K  + L FPSL TTTN +WCYL   K  H+   D+++S Y  W +S 
Sbjct: 1913 SQQPVTSLSLFNIKDTQQLAFPSLKTTTNFTWCYLLRQKSLHLPQKDQKTSAYTDWTVSA 1972

Query: 1635 YNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHL---P 1691
             NPN  G+ TK AL+LL SKQ   K  Y  A   H ++  LV SS  K  +++  L    
Sbjct: 1973 SNPNPLGLPTKVALALLNSKQNTGKSLYCQAITTHSKSDLLVYSSKWKSSLSKRALGNQK 2032

Query: 1692 SLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSNEEYVYVRGRGR 1751
            S V     KD + +  E+++         +  + EP RIKIF+GGYKSNEEYVYVRGRGR
Sbjct: 2033 STVVEFSNKDASEINSEQDKEN-------SLIKSEPRRIKIFDGGYKSNEEYVYVRGRGR 2085

Query: 1752 GKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQ 1811
            GKY+CEECGIRCKKPSMLKKHIRTHTDVRPY C +C+F+FKTKGNLTKHMKSKAHSKKC 
Sbjct: 2086 GKYICEECGIRCKKPSMLKKHIRTHTDVRPYHCTYCNFSFKTKGNLTKHMKSKAHSKKCV 2145

Query: 1812 ETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQ 1871
            + GV   L  E+ T        E  E      E    DLE+SD   + D + ++D+E+SQ
Sbjct: 2146 DLGVSVGLIDEQDT-------EESDEKQRFSYERSGYDLEESDGPDEDDNENEDDDEDSQ 2198

Query: 1872 DELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAE--------R 1923
             E    ++ +    P H      S +  P   D     T+   G      +        R
Sbjct: 2199 AESVLSATPSVTASPQHL--PSRSSLQDPVSTDEDVRITDCFSGVHTDPMDVLPRALLTR 2256

Query: 1924 LTASSCSMSSQSMPGL-PWLGPAPLGSVEKDTGSAL--SYKPVSPRRPWSPSKEAGSRPP 1980
            +T  S + S  +   L P          E DT  ++  S  P        P  E   R  
Sbjct: 2257 MTVLSTAQSDYNRKTLSPGKARQRAARDENDTIPSVDTSRSPCHQMSVDYPESEEILRSS 2316

Query: 1981 LARKH-SLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLC 2039
            +A K  ++T++ SS       R P A+A   P      G    A P   P+ Q   +TL 
Sbjct: 2317 MAGKAVAITQSPSS------VRLPPAAAEHSP--QTAAGMPSVASPHPDPQEQKQQITLQ 2368

Query: 2040 PLGRELAPRAHVLSKL 2055
            P     +P  H+ S L
Sbjct: 2369 PTPGLPSPHTHLFSHL 2384



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 46/140 (32%), Positives = 60/140 (42%), Gaps = 29/140 (20%)

Query: 2067 SPTRRWSPGQAESPP--RSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLL 2124
            SP  + S    ES    RS+  GK A+A   SPS+            V  PPA   H   
Sbjct: 2297 SPCHQMSVDYPESEEILRSSMAGK-AVAITQSPSS------------VRLPPAAAEH--- 2340

Query: 2125 SRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQ 2184
              SP+T A      S  P         ++ +P   L   H H+        FSHLPLHSQ
Sbjct: 2341 --SPQTAAGMPSVASPHPDPQE-QKQQITLQPTPGLPSPHTHL--------FSHLPLHSQ 2389

Query: 2185 HLTRAPCPLIPIGGIQMVQA 2204
              +R P  ++P+GGI +V A
Sbjct: 2390 QQSRTPYNMVPVGGIHVVPA 2409


>gi|123701326 zinc finger protein 831 [Homo sapiens]
          Length = 1677

 Score =  171 bits (432), Expect = 1e-41
 Identities = 272/1136 (23%), Positives = 424/1136 (37%), Gaps = 225/1136 (19%)

Query: 49   PAQELLAPQPFPGPSSVLREGSQEKT-GQQQKPPKRPPIEASVHISQLP---QHPLTPAF 104
            PA++  AP P P P +   + S   T G    PP++     +V +  LP    H + P  
Sbjct: 12   PARDQPAPTPGP-PGAPGGQASPHLTLGPVLLPPEQGLAPPTVFLKALPIPLYHTVPPGG 70

Query: 105  MSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPE------DLP 158
            + P  P  L+ GS       +  G     ++P L P+    P    +  P       ++ 
Sbjct: 71   LQPRAP--LVTGS-------LDGGNVPFILSPVLQPEG---PGPTQVGKPAAPTLTVNIV 118

Query: 159  GVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGER 218
            G   V  P      L PT  +  K R     GKY+C +C R C KPSVL+KHIRSHTGER
Sbjct: 119  GTLPVLSP-----GLGPTLGSPGKVRNA---GKYLCPHCGRDCLKPSVLEKHIRSHTGER 170

Query: 219  PYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLAS---GMGGEMYPHGLEMERIPGEEFEE 275
            P+PC  CG +FKT+SNLYKHR++  H   + L+S   G GG +   G +     GE    
Sbjct: 171  PFPCATCGIAFKTQSNLYKHRRTQTHLNNSRLSSESEGAGGGLLEEGDK----AGEPPRP 226

Query: 276  PTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSL 335
               GES        A+      LSP    PLL+  L       +    C  S  +  ++ 
Sbjct: 227  EGRGESRCQGMHEGASE---RPLSPGAHVPLLAKNL----DVRTEAAPCPGSAFADREAP 279

Query: 336  EDPPPFVEP----SSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKG---- 387
             D  P   P    +S  P    PE       K    L  ++    E+ + +   +G    
Sbjct: 280  WDSAPMASPGLPAASTQPWRKLPEQKSPTAGK-PCALQRQQATAAEKPWDAKAPEGRLRK 338

Query: 388  --STESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLST 445
              ST+SGY SRS+SAEQ  +P +    S +E      G  G       A           
Sbjct: 339  CESTDSGYLSRSDSAEQPHAPCSP-LHSLSEHSAESEGEGGPGPGPGVA---------GA 388

Query: 446  EDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLY 505
            E       L + + ++ E I +LI+ N+AVVD +++D+V+PR++ LS++ S++ P    Y
Sbjct: 389  EPGAREAGLELEKKRLEERIAQLISHNQAVVDDAQLDNVRPRKTGLSKQGSIDLPTPYTY 448

Query: 506  ----------------REPLSSHSEKTKPEQSLLSLQHP-----PSTAPPVPLLRSHSMP 544
                            R P    S  T P++S     H       +T   VP+ RS+S+P
Sbjct: 449  KDSFHFDIRALEPGRRRAPGPVRSTWTPPDKSRPLFFHSVPTQLSTTVECVPVTRSNSLP 508

Query: 545  --SAACTISTPHHPFRGSYSFDD----------HITDSEALSHSSHVFTSHPRMLKRQPA 592
                + T   P  P R  +S              +     LS S+ V + HPR L RQ A
Sbjct: 509  FVEGSRTWLEPREP-RDPWSRTQKPLSPRPGPARLGCRSGLS-STDVPSGHPRALVRQAA 566

Query: 593  IELPLGGEYSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARY 652
            +E         + PG    D A  P+++ + K +   +      +  G       CG R 
Sbjct: 567  VE---------DLPGTPIGD-ALVPAEDTDAKRTAAREAMAGKGRAGG-----RKCGQRR 611

Query: 653  KKRDNYEAHKKYYCSEL-QIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTP 711
             K  + E  + Y      +I + + A  H                               
Sbjct: 612  LKMFSQEKWQVYGDETFKRIYQKMKASPHGG----------------------------- 642

Query: 712  LRKRRKEKSLGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPT 771
              K+ +E  +G   E   F   K   GS G       +P +  ++P     S  +   P 
Sbjct: 643  --KKAREVGMGSGAE-LGFPLQKEAAGSSG------TVPTQDRRTPVHEDISAGATPEPW 693

Query: 772  GFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSP 831
            G  P   +    +E  K   T ++     +  S   + +       L G D P +   SP
Sbjct: 694  G-NPPALEASLVTEPTKHGETVAR-----RGDSDRPRVEEAVSSPALGGRDSPCSGSRSP 747

Query: 832  PPAPHGRSAHSLQ----PKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEE---- 883
              +P+GR     Q    P  ++  +++ P       P  PD + E   +     +E    
Sbjct: 748  LVSPNGRLELGWQMPPAPGPLKGGDVEAP------RPVWPDPKLEGGARGVGDVQETCLW 801

Query: 884  ----FQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVS 939
                 +WP R         +KLP ++K+L++ ++          +  P    P+Q +   
Sbjct: 802  AQTVLRWPSRGS-----GEDKLPSERKKLKVEDLHSWKQPEPVSAETP--GGPTQPA--- 851

Query: 940  LSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNV 999
                  S S ++ D    E P  S +   +                 E   S+       
Sbjct: 852  ------SLSSQKQDADPGEVPGGSKESARQ---------------VGEPLESSGASLAAA 890

Query: 1000 SHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQAS------LSR 1053
            S +      R K+      +   P+APAP   P+   PP+  +       +      L R
Sbjct: 891  SVALKRVGPRDKA------TPLHPAAPAPAEHPSLATPPQAPRVLSALADNAFSPKYLLR 944

Query: 1054 PPESELEV---APKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQ 1106
             P++E  +    P G + S++   SS  P  ++S             P  G  PG+
Sbjct: 945  LPQAETPLPLPIPWGPRHSQDSLCSSGWPEERASFVGSGLGTPLSPSPASGPSPGE 1000



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 125/471 (26%), Positives = 167/471 (35%), Gaps = 77/471 (16%)

Query: 1749 RGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK 1808
            R  GKY+C  CG  C KPS+L+KHIR+HT  RP+ C  C  AFKT+ NL KH +++ H  
Sbjct: 139  RNAGKYLCPHCGRDCLKPSVLEKHIRSHTGERPFPCATCGIAFKTQSNLYKHRRTQTHLN 198

Query: 1809 KCQETGVLEELEA---EEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDE 1865
              + +   E       EEG         EGR  S     H        +  S+       
Sbjct: 199  NSRLSSESEGAGGGLLEEGDKAGEPPRPEGRGESRCQGMH--------EGASERPLSPGA 250

Query: 1866 DEEESQDELSRPSSEAPPPGPPHALRA---DSSPILGPQPPDAPASGTEATRGSSVSEAE 1922
                    L   +  AP PG   A R    DS+P+     P  PA+ T+  R   + E +
Sbjct: 251  HVPLLAKNLDVRTEAAPCPGSAFADREAPWDSAPMAS---PGLPAASTQPWR--KLPEQK 305

Query: 1923 RLTASS-CSMSSQSMPGL--PWLGPAPLGSVEK--DTGSALSYKPVSPRRPWSPSKEAGS 1977
              TA   C++  Q       PW   AP G + K   T S    +  S  +P +P      
Sbjct: 306  SPTAGKPCALQRQQATAAEKPWDAKAPEGRLRKCESTDSGYLSRSDSAEQPHAPCS---- 361

Query: 1978 RPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLT 2037
              PL   HSL+++ +       +       P P     +PG     L     RL+     
Sbjct: 362  --PL---HSLSEHSAE------SEGEGGPGPGPGVAGAEPGAREAGLELEKKRLEERIAQ 410

Query: 2038 LCPLGR---------ELAPRAHVLSKLEGTTDPGLP------------RYSPTRRWSPGQ 2076
            L    +          + PR   LSK +G+ D   P               P RR +PG 
Sbjct: 411  LISHNQAVVDDAQLDNVRPRKTGLSK-QGSIDLPTPYTYKDSFHFDIRALEPGRRRAPGP 469

Query: 2077 AESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPA----PLPHKLLSRS---PE 2129
              S     PP K       S     H     L   V   P      LP    SR+   P 
Sbjct: 470  VRS--TWTPPDK-------SRPLFFHSVPTQLSTTVECVPVTRSNSLPFVEGSRTWLEPR 520

Query: 2130 TCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLP 2180
                PW    +  S  PGPA        S+     GH  A   +     LP
Sbjct: 521  EPRDPWSRTQKPLSPRPGPARLGCRSGLSSTDVPSGHPRALVRQAAVEDLP 571


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score =  106 bits (265), Expect = 2e-22
 Identities = 185/729 (25%), Positives = 257/729 (35%), Gaps = 124/729 (17%)

Query: 725  EEPPAFESTKSQFGSPGPSDAARNLP-------------LESTKSP-AEPSKSVPSLEGP 770
            E P    S+ S+  +  PS AAR  P             L S+ +P + P++S PS  G 
Sbjct: 203  EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262

Query: 771  --TGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSD-SLEQPSGLEGEDKPLAQ 827
                  P  PKP  G ++ +  + T               S  +   PSG +        
Sbjct: 263  PRAPAHPSQPKP-KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR------ 315

Query: 828  FPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRP---DTEPEPPPKEPEK---- 880
             P PPP     +A  L   L   P +  P  L    P  P    T P PP   P +    
Sbjct: 316  -PVPPP---DNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371

Query: 881  --TEEFQWPQRSQTLAQL--------PAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSR 930
              T   Q P   QT+  +        P+ + PP    L   +   S G  + +++     
Sbjct: 372  MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLT 431

Query: 931  SPSQESNVSLSGSSRSASFERDDHGKAEAP-----SPSSDMRPKPLGTHMLTVPSHHP-H 984
               +++  SL+  SR AS   D     +AP     SP       P  + + +  + HP  
Sbjct: 432  MSPRQTQASLTSPSRPASTPPDSP-PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ 490

Query: 985  AREMRRSASEQSPNVSHSAHMTETRSK----SFDYGSLSLTGP--------------SAP 1026
            A     S S Q+P  S      ET+S     S      SLT P              +A 
Sbjct: 491  ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS 550

Query: 1027 APVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLS 1086
            AP+  P    PP    C       L  PP       P+       P P +    A   L 
Sbjct: 551  APLTTPHLETPPCPAPC------PLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQ 604

Query: 1087 QISSAATSH-GGPPGGKGPGQDRPPLG--PTVPYTEALQVFHHPVAQTP------LHEKP 1137
             + S   S    PP    P    PPL   P+ P +  L     P  Q P      L + P
Sbjct: 605  GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 664

Query: 1138 YLPPPVSLFSFQHLVQHEPGQSPEFFS-TQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPT 1196
            + PPP             P  SP     +QA  SL + P  +PP PP    A P P+ P+
Sbjct: 665  FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP----ASP-PMSPS 719

Query: 1197 VLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVES 1256
               P     PQ  P  A  P + PPS    P  + SA       PL +   LQ+P    +
Sbjct: 720  ATPP-----PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774

Query: 1257 HLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSA---PPLALPACPDT 1313
             LP     ++PLA                + PP APPA ++ P  A   PP + P     
Sbjct: 775  SLP-----MSPLA----------------KPPPQAPPALATPPLQALPSPPASFPGQAPF 813

Query: 1314 MVSLVVPVR-VQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGAD 1372
              S  +P+  + T  P     +   L Q  V  S  +S T+  P+    P   T+V G  
Sbjct: 814  SPSASLPMSPLATPPPQAPPVLAAPLLQ--VPPSPPASPTLQAPRRPPTPGPDTSVSGPR 871

Query: 1373 VH-EVGPGP 1380
            +   + PGP
Sbjct: 872  LTLALAPGP 880



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 179/769 (23%), Positives = 267/769 (34%), Gaps = 141/769 (18%)

Query: 734  KSQFGSPGPSDAARNLPLESTKSPAEPSKSVP---------SLEGPTGFQPRTPKPGSGS 784
            K++ G+   + AAR   L + + P  P    P            G  G +P   +  +G 
Sbjct: 7    KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER--AGG 64

Query: 785  ESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPH-GRSAHSL 843
              G     ++      +   +  ++ +   P+   GE  P A+  SP P    GR++ + 
Sbjct: 65   IGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124

Query: 844  QPKLVRQPNIQ------VPEILVTEEPDRP--------DTE-PEPPPKEPEKTE------ 882
            +P  + Q  ++      V     TE P R         DT  P P    P          
Sbjct: 125  RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184

Query: 883  -EFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQ------- 934
             E   P+ + +    P  + P K        ++ +S  S+ E S    R PS        
Sbjct: 185  TEVGLPRPAPSARPRPPTEGPRKS-------VSSASEHSTTEPSPAARRRPSAGGGLQRP 237

Query: 935  -ESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSAS 993
               ++S S +  S+        +    +P+   +PKP G   L  P   P  ++   +  
Sbjct: 238  ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297

Query: 994  --EQSPNVSHSAHMTETRSKSFDYGS---LSLTGP-----SAPAPVAPPARVAPPERRKC 1043
                SP  + S   T+ R       +   L  T P     + P P+APP+  APP  +  
Sbjct: 298  PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL 357

Query: 1044 FLVRQASLSRPPES----------ELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAAT 1093
                    S+ P S           L+  P  +       PS   P +  +LS +  A T
Sbjct: 358  PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQ-ATT 416

Query: 1094 SHGGP-------------------------PGGKGPGQDRPPLGP--TVPYTEALQVFHH 1126
            S G P                         P    P  D PPL    ++P +  LQ    
Sbjct: 417  SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP--DSPPLQAPLSLPASPPLQTSLS 474

Query: 1127 PVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPP---LPP 1183
            P A +PL     + P  +L S   L  H P Q+P   S+  M  L +     PP    PP
Sbjct: 475  P-AVSPLSSPLTIHPLQALSS---LASHSP-QAP--LSSLIMPPLETQSSLAPPSLQTPP 527

Query: 1184 SLFQAPPLPLQPTVLHP------GQLHLPQLM--PHPANIPFRQPPSFLPMPYP-TSSAL 1234
            +    PPL   P++  P        L  P L   P PA  P + PPS L  P P T S++
Sbjct: 528  ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI 587

Query: 1235 SSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPA 1294
            ++    P Q+  AL  P      LP     L+PLAT      P  +    + LPP+  P 
Sbjct: 588  ATP---PPQAPPALASPP--LQGLPS--PPLSPLAT------PPPQAPPXLALPPLQAPP 634

Query: 1295 SSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVA 1354
            S  A     PLA P+ P    +L V +      P     +    S           A+  
Sbjct: 635  SPPASPPLSPLATPS-PQAPNALAVHLLQAPFSPPPSPPVQAPFSP---------PASPP 684

Query: 1355 LPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLP 1403
            +     PPS+      A   +V P P         A P P    P+  P
Sbjct: 685  VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733



 Score = 73.2 bits (178), Expect = 3e-12
 Identities = 211/970 (21%), Positives = 322/970 (33%), Gaps = 193/970 (19%)

Query: 486  PRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHSMPS 545
            P RS  S R +  +P          +H  + KP+   L    PP   PP         P 
Sbjct: 252  PARSGPSARGTPRAP----------AHPSQPKPKG--LQALRPPQVTPPRKDAAPALGPL 299

Query: 546  AACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYSSEE 605
            ++  ++TP              T +  +    +  T  P  L   P +  PL     S  
Sbjct: 300  SSSPLATP----------SPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS 349

Query: 606  PGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYY 665
              PS +   S P+         +T    +   +   I                       
Sbjct: 350  APPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTI----------------------- 386

Query: 666  CSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEE 725
               +Q+   +++ +  +P +  +    +  + +    L  T     +  R+ + SL    
Sbjct: 387  -PPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS 445

Query: 726  EPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSE 785
             P +         +P    A+   PL+++ SPA     V  L  P    P        S 
Sbjct: 446  RPASTPPDSPPLQAPLSLPASP--PLQTSLSPA-----VSPLSSPLTIHPLQALSSLASH 498

Query: 786  SGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAP-HGRSAHSLQ 844
            S  +   +S  +  ++  SS         P+ L     PL   PS  P P    SA    
Sbjct: 499  S-PQAPLSSLIMPPLETQSSLAPPSLQTPPASLT--TPPLENLPSLAPPPLQTASAPLTT 555

Query: 845  PKLVRQP-----NIQVPEI-LVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPA 898
            P L   P      +Q P   L T  P+ P +   PPP+ P              LA  P 
Sbjct: 556  PHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPP------------ALASPPL 603

Query: 899  EKLPPKKKRLRLAEMAQSSGESSFESSVP-LSRSPSQESNVSLSGSSRSASFERDDHGKA 957
            + LP       L+ +A    ++    ++P L   PS  ++  LS  +             
Sbjct: 604  QGLPSPP----LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLA------------- 646

Query: 958  EAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQ-SPNVSHSAHMTETRSKSFDYG 1016
              PSP +   P  L  H+L  P   P +  ++   S   SP VS SA        S    
Sbjct: 647  -TPSPQA---PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS---- 698

Query: 1017 SLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSS 1076
               L  P    P +PPA  +PP           S + PP++   +A    Q    P P +
Sbjct: 699  ---LAAPPLQVPPSPPA--SPP--------MSPSATPPPQAPPPLAAPPLQVP--PSPPA 743

Query: 1077 SKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEK 1136
            S P + S+             PP    P    PPL   VP +    +   P+A+ P    
Sbjct: 744  SPPMSPSAT------------PPPRVPPLLAAPPL--QVPPSPPASLPMSPLAKPP---- 785

Query: 1137 PYLPPPVSLFSFQHLVQHE---PGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPL 1193
            P  PP ++    Q L       PGQ+P   S     S L++P   PP  P +  AP L +
Sbjct: 786  PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP---PPQAPPVLAAPLLQV 842

Query: 1194 QPTVLHPGQLHLPQLMPHPA--------NIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQ 1245
             P+      L  P+  P P          +     P   P P  + S+  SG  L   S 
Sbjct: 843  PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902

Query: 1246 FALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYS-------SDIRLPPVAPPASSSA 1298
             A   P ++  +         P    +A   P  E +       S    PP+A   +  A
Sbjct: 903  SATSTPEELRGY------DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA 956

Query: 1299 PTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKF 1358
            P   PP   P   D + ++      +T  P                     SAT A    
Sbjct: 957  PLPWPPATGPGSADGLCTI-----YETEGP--------------------ESATPAPGAL 991

Query: 1359 EEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSL 1418
            +  PS GT+  G      G G S  S +Q+R    P   +  ++ +     L S ++L L
Sbjct: 992  DPGPSPGTS-GGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQH----LLSRTLL-L 1045

Query: 1419 EGSSSTAGGS 1428
              +   AGGS
Sbjct: 1046 AAAEGAAGGS 1055



 Score = 63.9 bits (154), Expect = 2e-09
 Identities = 146/591 (24%), Positives = 203/591 (34%), Gaps = 86/591 (14%)

Query: 1865 EDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEA--- 1921
            E   +S    S  S+  P P    A R   S   G Q P + +  + AT  SS + +   
Sbjct: 203  EGPRKSVSSASEHSTTEPSP----AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 258

Query: 1922 ERLTASSCSMSSQSMP-GLPWLGPAPLGSVEKDTGSALSYKPVSP----------RRPWS 1970
             R T  + +  SQ  P GL  L P  +    KD   AL     SP           RP  
Sbjct: 259  ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVP 318

Query: 1971 PSKEAGS--------RPPLARKHSLTK-NDSSPQRCSPAREPQASAPS--PPGLHVDPGR 2019
            P   A +         PPLA    L   + S+P        P A+ PS  PP +   P +
Sbjct: 319  PPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ 378

Query: 2020 GMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRW------- 2072
               +L    P +Q+ P +L     +  P    LS L+ TT  G P    T  +       
Sbjct: 379  APPSLQT-IPPIQV-PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436

Query: 2073 ------SPGQAESPPRSAPPGKWALAGPGSPSAGEH-GPGLG-LDPRVLFPPAPLPHKLL 2124
                  SP +  S P  +PP +  L+ P SP       P +  L   +   P      L 
Sbjct: 437  TQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLA 496

Query: 2125 SRSPETCAS-----PWKAESR-SPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSH 2178
            S SP+   S     P + +S  +P     P   L++ P   L       L        + 
Sbjct: 497  SHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT------AS 550

Query: 2179 LPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQ 2238
             PL + HL   PCP               A P+ L  P     S  +        A  + 
Sbjct: 551  APLTTPHLETPPCP---------APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP 601

Query: 2239 E-RGRWSPTESSSASVSPVA--KVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGT 2295
              +G  SP  S  A+  P A   ++   L +       P         P  P     H  
Sbjct: 602  PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 661

Query: 2296 GAPAEPTPT---HSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSS 2352
             AP  P P+    +P +PP + P  P     +Q+  P L +P     P P A+PP+  S+
Sbjct: 662  QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA-PPSLAAPPLQVPPSPPASPPMSPSA 720

Query: 2353 SVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPP 2403
            +           P     L+  P     SP  S    P A    P  RVPP
Sbjct: 721  TPP---------PQAPPPLAAPPLQVPPSPPASPPMSPSA---TPPPRVPP 759



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 146/572 (25%), Positives = 193/572 (33%), Gaps = 138/572 (24%)

Query: 1875 SRPSSEAPPPGPPHALRADSSPILGPQ---PPDAPASGTEATRGSSVSEAERLTASSCSM 1931
            +R  +  P PG P    A  S   G +   P  AP++     R    +E  R + SS S 
Sbjct: 160  ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA-----RPRPPTEGPRKSVSSASE 214

Query: 1932 SSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKND 1991
             S + P                        P + RRP   S   G + P +R  S +   
Sbjct: 215  HSTTEPS-----------------------PAARRRP---SAGGGLQRPASRSLSSSATP 248

Query: 1992 -SSPQRCSPARE--PQASA----PSPPGLH------VDPGRGMGALPCGSPRLQLSPL-T 2037
             SSP R  P+    P+A A    P P GL       V P R   A P   P L  SPL T
Sbjct: 249  LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR-KDAAPALGP-LSSSPLAT 306

Query: 2038 LCPLG---RELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGP 2094
              P G   R + P  +  + L  T  P  P  +P           P  SAPP    L  P
Sbjct: 307  PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL------PLAPPSPSAPPSLQTLPSP 360

Query: 2095 GSPSAGEHGPGLGLDPRVL------FPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGP 2148
             +    +  P +   P          PP  +PH L S S +   SP    S   + S   
Sbjct: 361  PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS--- 417

Query: 2149 AHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGA 2208
               L S    A H F      +T+ ++ S            P    P+     + A P  
Sbjct: 418  ---LGSPTLQATHSFLTMSPRQTQASLTS-----PSRPASTPPDSPPLQAPLSLPASPPL 469

Query: 2209 HPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTE--SSSASVSPVAKVSKFTLSS 2266
              +L P      VS  S   S LT            P +  SS AS SP A +S   +  
Sbjct: 470  QTSLSPA-----VSPLS---SPLT----------IHPLQALSSLASHSPQAPLSSLIM-- 509

Query: 2267 ELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPP----DTLPRPPQGRR 2322
                                PP  T      P+  TP  S  TPP     +L  PP    
Sbjct: 510  --------------------PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA 549

Query: 2323 AAQSWSPRLESPRAP------TNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPR 2376
            +A   +P LE+P  P        P P  TPP +  SS+      +   P     L+  P 
Sbjct: 550  SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI------ATPPPQAPPALASPPL 603

Query: 2377 TRQDSP--KPSGSGEPRAHPH--QPEDRVPPN 2404
                SP   P  +  P+A P    P  + PP+
Sbjct: 604  QGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635



 Score = 62.4 bits (150), Expect = 5e-09
 Identities = 130/531 (24%), Positives = 179/531 (33%), Gaps = 97/531 (18%)

Query: 1874 LSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSS 1933
            L+ P  E PP   P  L+A  SP+  P PP+ P+S   AT       A         ++S
Sbjct: 553  LTTPHLETPPCPAPCPLQAPPSPLTTP-PPETPSS--IATPPPQAPPA---------LAS 600

Query: 1934 QSMPGLPWLGPAPLGSVEKDTGSALSYKPV----SP--RRPWSPSKEAGSRPPLARKHSL 1987
              + GLP    +PL +        L+  P+    SP    P SP      + P A    L
Sbjct: 601  PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 660

Query: 1988 TKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAP 2047
             +   SP    P + P +   SPP             P  +P  Q  P    P   ++ P
Sbjct: 661  LQAPFSPPPSPPVQAPFSPPASPP-----------VSPSATPPSQAPPSLAAP-PLQVPP 708

Query: 2048 RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLG 2107
                       + P  P  SP+   +P     PP +APP +   + P SP          
Sbjct: 709  -----------SPPASPPMSPSA--TPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT--- 752

Query: 2108 LDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHP--LSSRPFSALHDFHG 2165
                   PP  +P  L +   +   SP  +   SP   P P  P  L++ P  AL     
Sbjct: 753  -------PPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPA 805

Query: 2166 HILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTL-------LPGPTA 2218
                +   +  + LP+          P +    +  V   P A PTL        PGP  
Sbjct: 806  SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 865

Query: 2219 AWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSS--ELEGGDYPKE 2276
                  S  G  LT A         S + SS+ S   +A  S    S+  EL G D   E
Sbjct: 866  ------SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 919

Query: 2277 RERTGGGPGRPPD-----------WTPHGT------GAPAEPTPTHSPCTPPDTLPRPPQ 2319
                GG    PP            W+          GAP  P P      PP T P    
Sbjct: 920  ----GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP-----WPPATGPGSAD 970

Query: 2320 GRRAAQSWSPRLESPRAPTNPEPSATPPLD-RSSSVGCLAEASARFPARTR 2369
            G            +  AP   +P  +P      ++ G  A AS+R P + R
Sbjct: 971  GLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 1021



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 137/558 (24%), Positives = 182/558 (32%), Gaps = 138/558 (24%)

Query: 1874 LSRPSSEAPP-----PGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASS 1928
            L+ PS  APP     P PP    + + P +   P  AP S              ++  S 
Sbjct: 343  LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPS-------LQTIPPIQVPHSL 395

Query: 1929 CSMSSQSMPGLPWLGPAPLGSVEKDTG-------SALSYKPVSPRRPW----SPSKEAGS 1977
             S S Q+ P      P  L S++  T        +  S+  +SPR+      SPS+ A +
Sbjct: 396  TSPSLQAPPS-----PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAST 450

Query: 1978 ---RPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLS 2034
                PPL    SL  +       SPA  P +S      L + P + + +L   SP+  LS
Sbjct: 451  PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSP-----LTIHPLQALSSLASHSPQAPLS 505

Query: 2035 PLTLCPLGRE--LAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALA 2092
             L + PL  +  LAP +        TT P                E+ P  APP     +
Sbjct: 506  SLIMPPLETQSSLAPPSLQTPPASLTTPP---------------LENLPSLAPPPLQTAS 550

Query: 2093 GPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSR-SPETCASPWKAESRSPSCSPGPAHP 2151
             P +             P +  PP P P  L +  SP T   P   E+ S   +P P  P
Sbjct: 551  APLTT------------PHLETPPCPAPCPLQAPPSPLTTPPP---ETPSSIATPPPQAP 595

Query: 2152 --LSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAH 2209
              L+S P   L       LA         L L    L   P P           A P   
Sbjct: 596  PALASPPLQGLPSPPLSPLATPPPQAPPXLALPP--LQAPPSP----------PASPPLS 643

Query: 2210 PTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELE 2269
            P   P P A          +  +       +  +SP   +S  VSP A            
Sbjct: 644  PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP--ASPPVSPSAT----------- 690

Query: 2270 GGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPP--DTLPRPPQGRRAAQSW 2327
                             PP   P    AP    P   P +PP   +   PPQ        
Sbjct: 691  -----------------PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA------- 726

Query: 2328 SPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGS 2387
             P L +P     P P A+PP+            SA  P R   L   P   Q  P P   
Sbjct: 727  PPPLAAPPLQVPPSPPASPPM----------SPSATPPPRVPPLLAAP-PLQVPPSP--- 772

Query: 2388 GEPRAHPHQPEDRVPPNA 2405
              P + P  P  + PP A
Sbjct: 773  --PASLPMSPLAKPPPQA 788



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 127/483 (26%), Positives = 165/483 (34%), Gaps = 112/483 (23%)

Query: 2000 AREPQASAPSPPGLHVDPGRGMGALPCGSPRLQ--LSPLTLCPLGRELA----PRAHVLS 2053
            AR P A AP   GL       +   P GSPR    ++P  L  LG   A    P A    
Sbjct: 14   ARTPAARAP---GL-------LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63

Query: 2054 KLEGTTDP-GLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDP-- 2110
             + G T P   PR  PTR  S G +   P S PP      G  +P A    PG    P  
Sbjct: 64   GIGGATIPESAPRAGPTR--SAGTSSRNPASRPPASGR--GERAPPAKNTSPGPVSSPGR 119

Query: 2111 -RVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCS--------------PGPAHPLSSR 2155
                  P PL  K L  S E   +  KA + +P  S              PG   P  +R
Sbjct: 120  ASGTTRPGPLGQKGLRISAEETVARGKA-TEAPKRSALSAGARRDTSGPTPGTPSPAMAR 178

Query: 2156 PFSALHDFHGHILARTEENIFSHLPLH---------SQHLTRAPCPLIPI-----GGIQM 2201
               A     G  L R   +     P           S+H T  P P         GG+Q 
Sbjct: 179  RSRAAGTEVG--LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236

Query: 2202 VQARP-GAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRW----------SPTESSS 2250
              +R   +  T L  P     SG S  G+    A  +Q + +            P + ++
Sbjct: 237  PASRSLSSSATPLSSPAR---SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293

Query: 2251 ASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPD--WTP-HGTGAPAEPTPTHSP 2307
             ++ P+   S   L++    G        T   P  PPD   TP   T  P+ P  T  P
Sbjct: 294  PALGPL---SSSPLATPSPSG--------TKARPVPPPDNAATPLPATLPPSPPLATPLP 342

Query: 2308 CTPP--------DTLPRPP----------------QGRRAAQSWSPRLESPRAPTNPEPS 2343
              PP         TLP PP                Q   + Q+  P ++ P + T+P   
Sbjct: 343  LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQT-IPPIQVPHSLTSPSLQ 401

Query: 2344 ATP-PLDRSSSVGCLAEASARFPARTRNLSGEPRTRQ---DSPKPSGSGEPRAHPHQPED 2399
            A P PL  SS     +  S    A    L+  PR  Q    SP    S  P + P Q   
Sbjct: 402  APPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL 461

Query: 2400 RVP 2402
             +P
Sbjct: 462  SLP 464



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 35/119 (29%), Positives = 50/119 (42%), Gaps = 35/119 (29%)

Query: 442 PLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRS-SMESP 500
           PL T   P++ PLS P T                        + P ++  S  S S ++P
Sbjct: 468 PLQTSLSPAVSPLSSPLT------------------------IHPLQALSSLASHSPQAP 503

Query: 501 KSSLYREPLSSHSEKTKPEQSLLSLQHPPS--TAPP---VPLLRSHSMPSAACTISTPH 554
            SSL   PL + S    P     SLQ PP+  T PP   +P L    + +A+  ++TPH
Sbjct: 504 LSSLIMPPLETQSSLAPP-----SLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH 557



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 42/171 (24%), Positives = 67/171 (39%), Gaps = 12/171 (7%)

Query: 16  SPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTG 75
           +P    TK   +    +++ P P +   +   +    L  P P   P S+    S   T 
Sbjct: 306 TPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP-SAPPSLQTLPSPPATP 364

Query: 76  QQQKPPKR--PPIEASVHISQLPQ----HPLT-PAFMSPGKPEHL--LEGSTWQLVDPMR 126
             Q PP    PP++A   +  +P     H LT P+  +P  P  L  L+ +T      ++
Sbjct: 365 PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424

Query: 127 PGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPR--PSQVSLKP 175
              S   ++P     S   PS  +  PP+  P    + +P   P Q SL P
Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSP 475



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 34/131 (25%), Positives = 46/131 (35%), Gaps = 25/131 (19%)

Query: 38  PGSGTAATQESPAQELLAPQP-FPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLP 96
           P     A    P Q L +P   FPG +      S   +     PP+ PP+ A+  +   P
Sbjct: 785 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 844

Query: 97  QHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSF--------VAPGLHPQSQLLPSH 148
             P +P   +P +P                PGP  S         +APG  P     PS 
Sbjct: 845 SPPASPTLQAPRRPP--------------TPGPDTSVSGPRLTLALAPGPPPPPSRSPS- 889

Query: 149 ASIIPPEDLPG 159
            S +   DL G
Sbjct: 890 -STLSGPDLAG 899


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 151/594 (25%), Positives = 212/594 (35%), Gaps = 98/594 (16%)

Query: 849  RQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRL 908
            R P  + P +L      RP   P PPP           P     L  L A     +K   
Sbjct: 15   RTPAARAPGLLTP----RPPGSPRPPP-----------PVTPAALRVLGAAGAVGRKP-- 57

Query: 909  RLAEMAQSSGESSFESSVPLSRSPSQESNVSLSG-SSRSASFERDDHGKAEAPSPSSDM- 966
             LAE A   G ++   S P +  P++ S    SG   R+   +    G   +P  +S   
Sbjct: 58   -LAERAGGIGGATIPESAPRA-GPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 115

Query: 967  RPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAP 1026
            RP PLG   L + +    AR     A ++S   + +   T              +GP+  
Sbjct: 116  RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT--------------SGPTPG 161

Query: 1027 APVAPPARVAPPERRKCFLVRQASLSRP-PESE---LEVAPKGRQESEEPQPSSSK-PSA 1081
             P    AR +     +  L R A  +RP P +E     V+      + EP P++ + PSA
Sbjct: 162  TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 221

Query: 1082 KSSLSQ-----ISSAATSHGGPP--GGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLH 1134
               L +     +SS+AT    P   G    G  R P  P+ P  + LQ    P    P  
Sbjct: 222  GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 281

Query: 1135 E----------------KPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSM 1178
            +                 P  PP  S       +   P   P   +T   S  L + +S 
Sbjct: 282  DAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF 341

Query: 1179 ---PPL----------PPSL----FQAPPLPLQPTVLHPGQLHLPQ----LMPHPANIPF 1217
               PPL          PP+L     QAPP P     L P     PQ    L  H    PF
Sbjct: 342  LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 401

Query: 1218 RQPPS---FLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAG 1274
              PPS     P   P S  +S     P Q+  +L  P       P     ++P AT    
Sbjct: 402  SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461

Query: 1275 LSPSTEYSSDIRL---PPVAPPASSSAPTSA---PPLALPACPDTMVSLVVPVR-VQTNM 1327
              P    +  ++L   PP APPA ++ P  A   PP + P       S  +P+  + T  
Sbjct: 462  APPPLA-APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520

Query: 1328 PSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVH-EVGPGP 1380
            P     +   L Q  V  S  +S T+  P+    P   T+V G  +   + PGP
Sbjct: 521  PQAPPVLAAPLLQ--VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 572



 Score = 72.0 bits (175), Expect = 7e-12
 Identities = 183/770 (23%), Positives = 257/770 (33%), Gaps = 153/770 (19%)

Query: 711  PLRKRRKEKSLGDEEEPPAFESTKSQFGSPG-PSDAARNLPL----------------ES 753
            P R  R   S   E  PPA  ++     SPG  S   R  PL                ++
Sbjct: 79   PTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 138

Query: 754  TKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLE 813
            T++P   + S  +    +G  P TP P     S    R    E+ + +   S       E
Sbjct: 139  TEAPKRSALSAGARRDTSGPTPGTPSPAMARRS----RAAGTEVGLPRPAPSARPRPPTE 194

Query: 814  QP-SGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPE 872
             P   +    +     PSP       +   LQ    R  +     +     P R      
Sbjct: 195  GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL---SSPARSGPSAR 251

Query: 873  PPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSP 932
              P+ P    +   P+     A  P +  PP+K      + A + G        PLS SP
Sbjct: 252  GTPRAPAHPSQ---PKPKGLQALRPPQVTPPRK------DAAPALG--------PLSSSP 294

Query: 933  SQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSA 992
                   L+  S SA            PSPS+    + L +   T PS        + + 
Sbjct: 295  -------LATPSPSAP-----------PSPSAPPSLQTLPSPPATPPS--------QATT 328

Query: 993  SEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVA-PPARVAPPERRKCFLVRQASL 1051
            S  SP +      T +   S     L+   P AP  +A PP +  P       L   A+ 
Sbjct: 329  SLGSPTLQ----ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 384

Query: 1052 SRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPL 1111
            S    + L V       S  P P    P +  +   +S +AT    PP    P    PPL
Sbjct: 385  SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT----PPSQAPPSLAAPPL 440

Query: 1112 GPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSL 1171
               VP +        P A  P    P  PPP++    Q  +   P Q+P   +T  + +L
Sbjct: 441  --QVPPSPPASPPMSPSATPP----PQAPPPLAAPPLQ--LAKPPPQAPPALATPPLQAL 492

Query: 1172 LSSPYSMP---------PLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPS 1222
             S P S P          LP S    PP P  P VL    L +P   P P   P  Q P 
Sbjct: 493  PSPPASFPGQAPFSPSASLPMSPLATPP-PQAPPVLAAPLLQVP---PSPPASPTLQAPR 548

Query: 1223 FLPMPYPTSS--------ALSSGFFLPLQSQFALQLPG-DVESHLPQIKTSLAPLA---- 1269
              P P P +S        AL+ G   P     +  L G D+  H     ++   L     
Sbjct: 549  RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 608

Query: 1270 --TGSAGLSPSTEYS---------SDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLV 1318
               G A  SP  +           S    PP+A   +  AP   PP   P   D + ++ 
Sbjct: 609  GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTI- 667

Query: 1319 VPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGP 1378
                 +T  P                     SAT A    +  PS GT+  G      G 
Sbjct: 668  ----YETEGP--------------------ESATPAPGALDPGPSPGTS-GGKAAAGAGA 702

Query: 1379 GPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGS 1428
            G S  S +Q+R    P   +  ++ +     L S ++L L  +   AGGS
Sbjct: 703  GASSRSPKQARLGELPLGALQASVVQH----LLSRTLL-LAAAEGAAGGS 747



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 124/509 (24%), Positives = 176/509 (34%), Gaps = 95/509 (18%)

Query: 1870 SQDELSRPSSEAPP-PGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASS 1928
            S   L+ PS  APP P  P +L+        P PP  P S    + GS   +A      S
Sbjct: 291  SSSPLATPSPSAPPSPSAPPSLQTL------PSPPATPPSQATTSLGSPTLQATHSFLPS 344

Query: 1929 CSMSSQSMP---GLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKH 1985
              +S  + P     P L   PL         A    P SP  P SP      + P A   
Sbjct: 345  PPLSPLATPPPQAPPALALPPL--------QAPPSPPASP--PLSPLATPSPQAPNALAV 394

Query: 1986 SLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGREL 2045
             L +   SP    P + P +   SPP             P  +P  Q  P    P   ++
Sbjct: 395  HLLQAPFSPPPSPPVQAPFSPPASPP-----------VSPSATPPSQAPPSLAAP-PLQV 442

Query: 2046 APRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPG 2105
             P           + P  P  SP+   +P     PP +APP + A   P +P      P 
Sbjct: 443  PP-----------SPPASPPMSPSA--TPPPQAPPPLAAPPLQLAKPPPQAP------PA 483

Query: 2106 LGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGP-AHPLSSRPFSALHDFH 2164
            L   P    P  P      S   +   SP  +   SP  +P P A P+ + P        
Sbjct: 484  LATPPLQALPSPP-----ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP-------- 530

Query: 2165 GHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQA-RPGAHPTLLPGPTAAWVSG 2223
               L +   +  +   L +      P P   + G ++  A  PG  P     P++  +SG
Sbjct: 531  ---LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST-LSG 586

Query: 2224 --FSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTG 2281
               +G  S  T   E        P   ++AS  P A+++    ++   G   P       
Sbjct: 587  PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG---PAPPLAFR 643

Query: 2282 GGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPE 2341
            G PG P  W P  TG    P      CT  +T           +S +P      AP   +
Sbjct: 644  GAPGAPLPWPP-ATG----PGSADGLCTIYET--------EGPESATP------APGALD 684

Query: 2342 PSATPPLD-RSSSVGCLAEASARFPARTR 2369
            P  +P      ++ G  A AS+R P + R
Sbjct: 685  PGPSPGTSGGKAAAGAGAGASSRSPKQAR 713



 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 105/483 (21%), Positives = 150/483 (31%), Gaps = 46/483 (9%)

Query: 1877 PSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSM 1936
            P+  + PP      RA  +    P P  +P   +  TR   + +     ++  +++    
Sbjct: 79   PTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 138

Query: 1937 PGLPWLGPAPLGSVEKDTGSALSY-KPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQ 1995
               P       G+    +G       P   RR  +   E G   P          +   +
Sbjct: 139  TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 198

Query: 1996 RCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKL 2055
              S A E   + PSP      P  G G        LQ       P  R L+  A  LS  
Sbjct: 199  SVSSASEHSTTEPSPAARR-RPSAGGG--------LQR------PASRSLSSSATPLSSP 243

Query: 2056 EGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPG-SPSAGEHGPGLG-LDPRVL 2113
                     R  P+ R +P     P +  P G  AL  P  +P   +  P LG L    L
Sbjct: 244  A--------RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 295

Query: 2114 FPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEE 2173
              P+P      S  P   A P      SP  +P P+   +S     L   H  + +    
Sbjct: 296  ATPSP------SAPPSPSAPPSLQTLPSPPATP-PSQATTSLGSPTLQATHSFLPSPPLS 348

Query: 2174 NIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTG 2233
             + +  P     L   P    P        A P   P   P P A          +  + 
Sbjct: 349  PLATPPPQAPPALALPPLQAPP-----SPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 403

Query: 2234 AREAQERGRWSPTESS--SASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWT 2291
                  +  +SP  S   S S +P ++      +  L+    P            PP   
Sbjct: 404  PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 463

Query: 2292 PHGTGAP---AEPTPTHSPC--TPP-DTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSAT 2345
            P     P   A+P P   P   TPP   LP PP        +SP    P +P    P   
Sbjct: 464  PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 523

Query: 2346 PPL 2348
            PP+
Sbjct: 524  PPV 526



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 98/408 (24%), Positives = 139/408 (34%), Gaps = 54/408 (13%)

Query: 1979 PPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGAL---PCGSPRLQLSP 2035
            P  A +   T+    P      R P A   SP G    PGR  G     P G   L++S 
Sbjct: 71   PESAPRAGPTRTSRPPASGRGERAPPAKNTSP-GPVSSPGRASGTTRPGPLGQKGLRISA 129

Query: 2036 LTLCPLGREL-APRAHVLSK-----LEGTTDPGLPRYSPTRRW-SPGQAESPPRSAPPGK 2088
                  G+   AP+   LS        G T PG P  +  RR  + G     PR AP  +
Sbjct: 130  EETVARGKATEAPKRSALSAGARRDTSGPT-PGTPSPAMARRSRAAGTEVGLPRPAPSAR 188

Query: 2089 WALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKL----------LSRSPETCASPWKAE 2138
                 P  P+ G               P+P   +            SRS  + A+P  + 
Sbjct: 189  -----PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243

Query: 2139 SRSPSCSPG----PAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLI 2194
            +RS   + G    PAHP   +P          +    ++   +  PL S  L   P P  
Sbjct: 244  ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA-TPSPSA 302

Query: 2195 PIGGIQMVQARPGAHPTL--LPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSAS 2252
            P          P A P+L  LP P A   S      +   G+   Q    + P+   S  
Sbjct: 303  P--------PSPSAPPSLQTLPSPPATPPSQ----ATTSLGSPTLQATHSFLPSPPLSPL 350

Query: 2253 VSPVAKVSKFTLSSELEGGDYPKERERTGG----GPGRPPDWTPHGTGAPAEPTPT---H 2305
             +P  +         L+    P             P  P     H   AP  P P+    
Sbjct: 351  ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 410

Query: 2306 SPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSS 2353
            +P +PP + P  P     +Q+  P L +P     P P A+PP+  S++
Sbjct: 411  APFSPPASPPVSPSATPPSQA-PPSLAAPPLQVPPSPPASPPMSPSAT 457



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 102/373 (27%), Positives = 130/373 (34%), Gaps = 72/373 (19%)

Query: 2000 AREPQASAPSPPGLHVDPGRGMGALPCGSPRLQ--LSPLTLCPLGRELA----PRAHVLS 2053
            AR P A AP   GL       +   P GSPR    ++P  L  LG   A    P A    
Sbjct: 14   ARTPAARAP---GL-------LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63

Query: 2054 KLEGTTDP-GLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRV 2112
             + G T P   PR  PTR   P  A      APP K    GP S      G         
Sbjct: 64   GIGGATIPESAPRAGPTRTSRP-PASGRGERAPPAKNTSPGPVSSPGRASGTTR------ 116

Query: 2113 LFPPAPLPHKLLSRSPETCASPWKA-ESRSPSCSPGPAHPLSSRPFSALHDFHGHILART 2171
               P PL  K L  S E   +  KA E+   S     A   +S P           +AR 
Sbjct: 117  ---PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS---PAMARR 170

Query: 2172 EENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDL 2231
                 + + L     +  P P  P  G +   +    H T  P P AA     +GGG   
Sbjct: 171  SRAAGTEVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEPSP-AARRRPSAGGGLQR 227

Query: 2232 TGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSE--LEGGDYPKERERTGGGPGRPPD 2289
              +R            S S+S +P++  ++   S+        +P + +  G    RPP 
Sbjct: 228  PASR------------SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 275

Query: 2290 WTP-HGTGAPA------EPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEP 2342
             TP     APA       P  T SP  PP   P  P               P   T P P
Sbjct: 276  VTPPRKDAAPALGPLSSSPLATPSPSAPPS--PSAP---------------PSLQTLPSP 318

Query: 2343 SATPPLDRSSSVG 2355
             ATPP   ++S+G
Sbjct: 319  PATPPSQATTSLG 331



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 57/215 (26%), Positives = 81/215 (37%), Gaps = 23/215 (10%)

Query: 2196 IGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSP 2255
            IGG  + ++ P A PT    P A+   G     +  T        GR S T         
Sbjct: 65   IGGATIPESAPRAGPTRTSRPPASG-RGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123

Query: 2256 VAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEP-------TPTHSPC 2308
              ++S     +  +  + PK R     G  R       GT +PA         T    P 
Sbjct: 124  GLRISAEETVARGKATEAPK-RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 182

Query: 2309 TPPDTLPRPP-QGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPAR 2367
              P   PRPP +G R + S +    S  + T P P+A     R S+ G L   ++R    
Sbjct: 183  PAPSARPRPPTEGPRKSVSSA----SEHSTTEPSPAARR---RPSAGGGLQRPASR---- 231

Query: 2368 TRNLSGEPRTRQDSPKPSGSGEPR--AHPHQPEDR 2400
            + + S  P +      PS  G PR  AHP QP+ +
Sbjct: 232  SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 266



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 34/131 (25%), Positives = 46/131 (35%), Gaps = 25/131 (19%)

Query: 38  PGSGTAATQESPAQELLAPQP-FPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLP 96
           P     A    P Q L +P   FPG +      S   +     PP+ PP+ A+  +   P
Sbjct: 477 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 536

Query: 97  QHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSF--------VAPGLHPQSQLLPSH 148
             P +P   +P +P                PGP  S         +APG  P     PS 
Sbjct: 537 SPPASPTLQAPRRPP--------------TPGPDTSVSGPRLTLALAPGPPPPPSRSPS- 581

Query: 149 ASIIPPEDLPG 159
            S +   DL G
Sbjct: 582 -STLSGPDLAG 591



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 55/243 (22%), Positives = 82/243 (33%), Gaps = 16/243 (6%)

Query: 1361 PPSKGTTVCGADVHEVGPGP-SGLSEEQSRAFPTPY----LRVPV--TLPERKGTSLSSE 1413
            PP+ G            PGP S          P P     LR+    T+   K T     
Sbjct: 85   PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKR 144

Query: 1414 SILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPCSVVLT 1473
            S LS      T+G +    SPA +        +    +   +++     E   P   V +
Sbjct: 145  SALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE--GPRKSVSS 202

Query: 1474 STEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALSHGTAPGSEALKE 1533
            ++E            +      L+  +S S   S T    PL  PA S  +A G+     
Sbjct: 203  ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT----PLSSPARSGPSARGTPRAPA 258

Query: 1534 YPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVL 1593
            +P    +P  +GL  L   +     +   P+L P SS PL+  S     S     S + L
Sbjct: 259  HPS---QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315

Query: 1594 QFP 1596
              P
Sbjct: 316  PSP 318


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 85.9 bits (211), Expect = 4e-16
 Identities = 159/662 (24%), Positives = 234/662 (35%), Gaps = 93/662 (14%)

Query: 755  KSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERR---TTSKEISVIQHTSSFEKSDS 811
            K+ A  +   P+   P    PR P        G  R     T   + V+    +  +   
Sbjct: 7    KAKAGAAARTPAARAPGLLTPRPP--------GSPRPPPPVTPAALRVLGAAGAVGRKPL 58

Query: 812  LEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEE-PDRPDTE 870
             E+  G+ G   P     S P A   RSA +      R P  + P     E  P   +T 
Sbjct: 59   AERAGGIGGATIP----ESAPRAGPTRSAGTSS----RNPASRPPASGRGERAPPAKNTS 110

Query: 871  PEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSR 930
            P P       +   +     Q   ++ AE+   + K     + +  S  +  ++S P   
Sbjct: 111  PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 170

Query: 931  SPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRR 990
            +PS     +++  SR+A  E         P+PS+  RP   G    +V S   H+     
Sbjct: 171  TPSP----AMARRSRAAGTEVG----LPRPAPSARPRPPTEGPRK-SVSSASEHSTTEPS 221

Query: 991  SASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQAS 1050
             A+ + P+         +RS S           S+  P++ PAR  P  R          
Sbjct: 222  PAARRRPSAGGGLQRPASRSLS-----------SSATPLSSPARSGPSAR---------G 261

Query: 1051 LSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPP 1110
              R P    +  PKG Q    PQ +  +  A  +L  +SS+  +   P          PP
Sbjct: 262  TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQ--SQAPP 319

Query: 1111 LGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSS 1170
              P  P++ +L         TPL   P  PP  S       +   P   P   +T   S 
Sbjct: 320  TLPATPHSSSLTC----QLATPL---PLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP 372

Query: 1171 LLSSPYSM---PPL----------PPSL----FQAPPLPLQPTVLHPGQLHLPQ----LM 1209
             L + +S    PPL          PP+L     QAPP P     L P     PQ    L 
Sbjct: 373  TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 432

Query: 1210 PHPANIPFRQPPS---FLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLA 1266
             H    PF  PPS     P   P S  +S     P Q+  +L  P       P     ++
Sbjct: 433  VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 492

Query: 1267 PLATGSAGLSPSTEYSSDIRL---PPVAPPASSSAPTSA---PPLALPACPDTMVSLVVP 1320
            P AT      P    +  ++L   PP APPA ++ P  A   PP + P       S  +P
Sbjct: 493  PSATPPPQAPPPLA-APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 551

Query: 1321 VR-VQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVH-EVGP 1378
            +  + T  P     +   L Q  V  S  +S T+  P+    P   T+V G  +   + P
Sbjct: 552  MSPLATPPPQAPPVLAAPLLQ--VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 609

Query: 1379 GP 1380
            GP
Sbjct: 610  GP 611



 Score = 79.0 bits (193), Expect = 5e-14
 Identities = 138/578 (23%), Positives = 192/578 (33%), Gaps = 107/578 (18%)

Query: 849  RQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRL 908
            R P  + P +L      RP   P PPP           P     L  L A     +K   
Sbjct: 15   RTPAARAPGLLTP----RPPGSPRPPP-----------PVTPAALRVLGAAGAVGRKP-- 57

Query: 909  RLAEMAQSSGESSFESSVPLS---RSPSQESNVSLSGSSRSASFERDDHGKAEAPSP--- 962
             LAE A   G ++   S P +   RS    S    S    S   ER    K  +P P   
Sbjct: 58   -LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116

Query: 963  ----SSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSL 1018
                S   RP PLG   L + +    AR     A ++S   + +   T            
Sbjct: 117  PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT------------ 164

Query: 1019 SLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRP-PESE---LEVAPKGRQESEEPQP 1074
              +GP+   P    AR +     +  L R A  +RP P +E     V+      + EP P
Sbjct: 165  --SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP 222

Query: 1075 SSSK-PSAKSSLSQ-----ISSAATSHGGPP--GGKGPGQDRPPLGPTVPYTEALQVFHH 1126
            ++ + PSA   L +     +SS+AT    P   G    G  R P  P+ P  + LQ    
Sbjct: 223  AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282

Query: 1127 PVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLF 1186
            P    P  +                            +  A+  L SSP + P  P +  
Sbjct: 283  PQVTPPRKD----------------------------AAPALGPLSSSPLATPS-PSAAL 313

Query: 1187 QAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQ-PPSFLPMPYPTSSALSSGFFLPLQSQ 1245
            Q+   P  P   H   L      P P   P    PPS   +P P ++        P Q+ 
Sbjct: 314  QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATP-------PSQAT 366

Query: 1246 FALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPL 1305
             +L  P    +H       L+PLAT      P  +    + LPP+  P S  A     PL
Sbjct: 367  TSLGSPTLQATHSFLPSPPLSPLAT------PPPQAPPALALPPLQAPPSPPASPPLSPL 420

Query: 1306 ALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKG 1365
            A P+ P    +L V +      P     +    S           A+  +     PPS+ 
Sbjct: 421  ATPS-PQAPNALAVHLLQAPFSPPPSPPVQAPFSP---------PASPPVSPSATPPSQA 470

Query: 1366 TTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLP 1403
                 A   +V P P         A P P    P+  P
Sbjct: 471  PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 508



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 175/758 (23%), Positives = 256/758 (33%), Gaps = 125/758 (16%)

Query: 724  EEEPPAFESTKSQFGSPG-PSDAARNLPL----------------ESTKSPAEPSKSVPS 766
            E  PPA  ++     SPG  S   R  PL                ++T++P   + S  +
Sbjct: 101  ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 160

Query: 767  LEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQP-SGLEGEDKPL 825
                +G  P TP P     S    R    E+ + +   S       E P   +    +  
Sbjct: 161  RRDTSGPTPGTPSPAMARRS----RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS 216

Query: 826  AQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQ 885
               PSP       +   LQ    R  +     +     P R        P+ P    +  
Sbjct: 217  TTEPSPAARRRPSAGGGLQRPASRSLSSSATPL---SSPARSGPSARGTPRAPAHPSQ-- 271

Query: 886  WPQRSQTLAQLPAEKLPPKKKRL-RLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSS 944
             P+     A  P +  PP+K     L  ++ S   +   S+   S++P     +  +  S
Sbjct: 272  -PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPP---TLPATPHS 327

Query: 945  RSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAH 1004
             S + +         PSPS+    + L +   T PS        + + S  SP +     
Sbjct: 328  SSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS--------QATTSLGSPTLQ---- 375

Query: 1005 MTETRSKSFDYGSLSLTGPSAPAPVA-PPARVAPPERRKCFLVRQASLSRPPESELEVAP 1063
             T +   S     L+   P AP  +A PP +  P       L   A+ S    + L V  
Sbjct: 376  ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 435

Query: 1064 KGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQV 1123
                 S  P P    P +  +   +S +AT    PP    P    PPL   VP +     
Sbjct: 436  LQAPFSPPPSPPVQAPFSPPASPPVSPSAT----PPSQAPPSLAAPPL--QVPPSPPASP 489

Query: 1124 FHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMP---- 1179
               P A  P    P  PPP++    Q  +   P Q+P   +T  + +L S P S P    
Sbjct: 490  PMSPSATPP----PQAPPPLAAPPLQ--LAKPPPQAPPALATPPLQALPSPPASFPGQAP 543

Query: 1180 -----PLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSS-- 1232
                  LP S    PP P  P VL    L +P   P P   P  Q P   P P P +S  
Sbjct: 544  FSPSASLPMSPLATPP-PQAPPVLAAPLLQVP---PSPPASPTLQAPRRPPTPGPDTSVS 599

Query: 1233 ------ALSSGFFLPLQSQFALQLPG-DVESHLPQIKTSLAPLA------TGSAGLSPST 1279
                  AL+ G   P     +  L G D+  H     ++   L        G A  SP  
Sbjct: 600  GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 659

Query: 1280 EYS---------SDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSY 1330
            +           S    PP+A   +  AP   PP   P   D + ++      +T  P  
Sbjct: 660  DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTI-----YETEGP-- 712

Query: 1331 GSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRA 1390
                               SAT A    +  PS GT+  G      G G S  S +Q+R 
Sbjct: 713  ------------------ESATPAPGALDPGPSPGTS-GGKAAAGAGAGASSRSPKQARL 753

Query: 1391 FPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGS 1428
               P   +  ++ +     L S ++L L  +   AGGS
Sbjct: 754  GELPLGALQASVVQH----LLSRTLL-LAAAEGAAGGS 786



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 128/560 (22%), Positives = 161/560 (28%), Gaps = 91/560 (16%)

Query: 1875 SRPSSEAPPPGPPHALRADSSPILG-------PQPPDAPASGTEATRGSSVSEAERLTAS 1927
            +R  +  P PG P    A  S   G       P P   P   TE  R S  S +E  T  
Sbjct: 160  ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 219

Query: 1928 SCSMS----------------SQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSP 1971
                +                S S    P   PA  G   + T  A    P  P +P   
Sbjct: 220  PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA----PAHPSQPKPK 275

Query: 1972 SKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAP----SPPGLHVDPGRGMGALPCG 2027
              +A   P +            P   SP   P  SA     +PP L   P          
Sbjct: 276  GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLA 335

Query: 2028 SPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAES----PPRS 2083
            +P     P    P   +  P        + TT  G P    T  + P    S    PP  
Sbjct: 336  TPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 395

Query: 2084 APPGKWAL----AGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAES 2139
            APP   AL    A P  P++    P     P+    P  L   LL        SP     
Sbjct: 396  APPA-LALPPLQAPPSPPASPPLSPLATPSPQA---PNALAVHLLQAPFSPPPSPPVQAP 451

Query: 2140 RSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGG- 2198
             SP  SP P  P ++ P  A        L        S  P  S   T  P    P+   
Sbjct: 452  FSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPAS--PPMSPSATPPPQAPPPLAAP 508

Query: 2199 -IQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVA 2257
             +Q+ +  P A P L   P  A  S              A   G+   + S+S  +SP+A
Sbjct: 509  PLQLAKPPPQAPPALATPPLQALPS------------PPASFPGQAPFSPSASLPMSPLA 556

Query: 2258 KVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLP-R 2316
                                         PP   P    AP    P   P +P    P R
Sbjct: 557  ----------------------------TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 588

Query: 2317 PPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASA--RFPARTRNLSGE 2374
            PP          PRL    AP  P P +  P    S       +S+    P   R     
Sbjct: 589  PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG 648

Query: 2375 PRTRQDSPKPSGSGEPRAHP 2394
            P     +  P  +     HP
Sbjct: 649  PEGGAAASPPPDAELAACHP 668



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 115/456 (25%), Positives = 150/456 (32%), Gaps = 97/456 (21%)

Query: 1874 LSRPSSEAPPPGPPHALRADSSPILGPQPP-----DAPASGTEATRGSSVSEAERLTASS 1928
            L+ PS +AP     H L+A  SP   P PP       PAS   +   +  S+A    A+ 
Sbjct: 420  LATPSPQAPNALAVHLLQAPFSP--PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 477

Query: 1929 CSMSSQSMPGLPWLGPAPLGSVEKDTGSA------LSYKPVSPRRPWSPSKEAGSRPPLA 1982
                  S P  P + P+     +     A          P +P    +P  +A   PP +
Sbjct: 478  PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS 537

Query: 1983 RKHSLTKNDSSPQRCSPAREPQASAP---SPPGLHVDPGRGMGALPCGSPRLQLS----- 2034
                   + S+    SP   P   AP   + P L V P       P  SP LQ       
Sbjct: 538  FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS------PPASPTLQAPRRPPT 591

Query: 2035 ------------PLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSP-------- 2074
                         L L P G    P     S L G   P L  +S +   +P        
Sbjct: 592  PGPDTSVSGPRLTLALAP-GPPPPPSRSPSSTLSG---PDLAGHSSSATSTPEELRGYDS 647

Query: 2075 ----GQAESPPRSAP-----PGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKL-- 2123
                G A SPP  A      P  W+  GP  P A    PG  L     +PPA  P     
Sbjct: 648  GPEGGAAASPPPDAELAACHPAAWS-RGPAPPLAFRGAPGAPLP----WPPATGPGSADG 702

Query: 2124 LSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHS 2183
            L    ET   P  A     +  PGP+   S           G   A       S  P   
Sbjct: 703  LCTIYET-EGPESATPAPGALDPGPSPGTSG----------GKAAAGAGAGASSRSP--- 748

Query: 2184 QHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGG-----GSDLTGAREA- 2237
                +A    +P+G +Q    +     TLL         G  GG     G  +TG   A 
Sbjct: 749  ---KQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAA 805

Query: 2238 ---QERGRW----SPTESSSASVSPVAKVSKFTLSS 2266
                E GRW    SP + S AS++ V   S   ++S
Sbjct: 806  LSDAELGRWAELLSPLDESRASITSVTSFSPDDVAS 841



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 59/223 (26%), Positives = 85/223 (38%), Gaps = 30/223 (13%)

Query: 2196 IGGIQMVQARPGAHPTLLPGPTA---AWVSGFSGGGSDLTGAREAQERGRWSPTESSSAS 2252
            IGG  + ++ P A PT   G ++   A     SG G     A+        SP  +S  +
Sbjct: 65   IGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124

Query: 2253 VSPVAKVSKFTLSSEL-----EGGDYPKERERTGGGPGRPPDWTPHGTGAPAEP------ 2301
                       +S+E      +  + PK R     G  R       GT +PA        
Sbjct: 125  RPGPLGQKGLRISAEETVARGKATEAPK-RSALSAGARRDTSGPTPGTPSPAMARRSRAA 183

Query: 2302 -TPTHSPCTPPDTLPRPP-QGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAE 2359
             T    P   P   PRPP +G R + S +    S  + T P P+A     R S+ G L  
Sbjct: 184  GTEVGLPRPAPSARPRPPTEGPRKSVSSA----SEHSTTEPSPAARR---RPSAGGGLQR 236

Query: 2360 ASARFPARTRNLSGEPRTRQDSPKPSGSGEPR--AHPHQPEDR 2400
             ++R    + + S  P +      PS  G PR  AHP QP+ +
Sbjct: 237  PASR----SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 275



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 34/131 (25%), Positives = 46/131 (35%), Gaps = 25/131 (19%)

Query: 38  PGSGTAATQESPAQELLAPQP-FPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLP 96
           P     A    P Q L +P   FPG +      S   +     PP+ PP+ A+  +   P
Sbjct: 516 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 575

Query: 97  QHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSF--------VAPGLHPQSQLLPSH 148
             P +P   +P +P                PGP  S         +APG  P     PS 
Sbjct: 576 SPPASPTLQAPRRPP--------------TPGPDTSVSGPRLTLALAPGPPPPPSRSPS- 620

Query: 149 ASIIPPEDLPG 159
            S +   DL G
Sbjct: 621 -STLSGPDLAG 630


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 229/1013 (22%), Positives = 345/1013 (34%), Gaps = 169/1013 (16%)

Query: 739  SPGPSDAARNLPLESTKSPAEPSK-SVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEI 797
            SP P  + +  P  S  +P  P   ++P  E PT      P P  G  +   ++  +  +
Sbjct: 855  SPTPP-SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSM 913

Query: 798  SVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPP----PAPHGRSAHSLQPKLVRQPNI 853
            +    +SS +K+ +   P G+     P    P+PP    P+P G  A +  PK    P  
Sbjct: 914  T----SSSPKKARATPAPKGIPASPSPKGA-PTPPAATPPSPKGGPA-TPSPKWAPTPPA 967

Query: 854  QVPEIL----VTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLR 909
              P        T  P    T P   P  P+       P+ + T    P    PP  K   
Sbjct: 968  ATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPT----PPAVTPPSPKGSP 1023

Query: 910  LAEMAQSSGESSFESSVPLSR-SPSQESNVSLSGSSRSASFERDDHGKAE-----APSPS 963
             A        +   ++ P  + SP+       + ++ +A+      G A      AP+P 
Sbjct: 1024 AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP 1083

Query: 964  SDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVS------HSAHMTETRSKSFDYGS 1017
            +   P P G      P   P    M  +A+  SP           A  T   +     G 
Sbjct: 1084 AATPPSPKGGPATPSPKGAP----MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139

Query: 1018 LSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSS 1077
            L+ T P   AP  P A    P+           L+ PP       PKG   +    P+++
Sbjct: 1140 LA-TPPPKGAPTTPAATPPSPK---------GGLATPP-------PKGAPTT----PAAT 1178

Query: 1078 KPSAKSSLSQIS---SAATSHGGPPGGKGPGQDRPPLG-PTVPYTEALQVFHHPVAQTPL 1133
             PS K  L+  S   +  T    PP  KG      P G PT P            A TP 
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP------------AATPP 1226

Query: 1134 HEKPYL--PPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPL 1191
              K  L  P P    +        P   P   +T       + P + PP        PP 
Sbjct: 1227 SPKGGLATPSPKGAPTTPAATPPSPKGGP---ATPPPKGAPTPPAATPPSLKGGLATPPH 1283

Query: 1192 P--LQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMP---YPTSSALSSGFFLPLQSQF 1246
                 P V+ P         P P   P   PP   P P    P S   S G   P  +  
Sbjct: 1284 KGAPNPAVVTP---------PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAP- 1333

Query: 1247 ALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLA 1306
                P  V    P+  T   P  T S+   P+T  S +   PP A P+    P   PP  
Sbjct: 1334 ---TPPAVTPPSPK-GTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSP 1389

Query: 1307 L--PACP----DTMVSLVVPV-----------RVQTNMPSYGSAMYTTLSQILVTQSQGS 1349
               PA P    D     V+P+           R     PS G      ++ + + ++  +
Sbjct: 1390 KRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT 1449

Query: 1350 SA-----------------TVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRA-F 1391
            SA                  V  P  +EPP+       +   +    P+ +      A  
Sbjct: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509

Query: 1392 PTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVK 1451
            P+    VP T   R+     + ++LS + + +T    + ++ PA ++    +T      K
Sbjct: 1510 PSSPKEVPATPSSRRDPIAPTATLLS-KKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK 1568

Query: 1452 EEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKE 1511
            E  A+ + +  E   P +V  ++ +    P+              E+L   +      KE
Sbjct: 1569 EAPATPSSK--EASSPPAVTPSTYKGAPSPK--------------ELLIPPAVTSPSPKE 1612

Query: 1512 IPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSSL 1571
             P  P       T P  E     P P G P    +TP S+K  DS   P   +    +++
Sbjct: 1613 APTPPAV-----TPPSPEKGPATPAPKGTPTSPPVTPSSLK--DSPTSPASVTCKMGATV 1665

Query: 1572 PLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWC 1631
            P   +   PAK +  T  K+VL  P+  +T  ++        P       ++SS  +   
Sbjct: 1666 P-QASKGLPAK-KGPTALKEVLVAPAPESTPIIT-------APTRKGPQTKKSSATSPPI 1716

Query: 1632 I---SLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSR 1681
                S  N +   +ST A   LL   QK S +T     A H   G L P  S+
Sbjct: 1717 CPDPSAKNGSKGPLSTVAPAPLL-PVQKDSSKTAKGKDASHSPKGPLAPPESK 1768



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 197/854 (23%), Positives = 289/854 (33%), Gaps = 135/854 (15%)

Query: 727  PPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEG------PTGFQPRTPKP 780
            PP    T      P P       P +   +P  P+ + PS +G      P G  P TP  
Sbjct: 1144 PPKGAPTTPAATPPSPKGGLATPPPKG--APTTPAATPPSPKGGLATPSPKG-APTTPAA 1200

Query: 781  GSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPP-------- 832
               S  G     + K        +       L  PS       P A  PSP         
Sbjct: 1201 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPP 1260

Query: 833  ---PAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDR--------PDTEPEPP---PKEP 878
               P P   +  SL+  L   P+   P   V   P          P   P PP   P  P
Sbjct: 1261 KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP 1320

Query: 879  EKTEEFQWPQRSQTLAQL--PAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQES 936
            + +     P+ + T   +  P+ K  P       +     +  SS E   P + +PS + 
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380

Query: 937  NVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTV-PSHHPHAREMRRSASEQ 995
              +++  S          G A  PSP  D    P    ++ + P   P     R  A+  
Sbjct: 1381 GPAMTPPSPK-------RGPA-IPSPKGD----PTSPAVIPLSPKKAPATPVTREGAATP 1428

Query: 996  SPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPA--RVAPPERRKCFLVRQ-ASLS 1052
            S        +T    K     S    GP+ P+    P    V PP  ++    +Q A+ S
Sbjct: 1429 SKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSS 1488

Query: 1053 RPPESELEVAPKGRQESEEPQPSSSK--PSAKSS-----------LSQISSAATSHGG-- 1097
             P ++    AP G        PSS K  P+  SS           LS+ + A  +     
Sbjct: 1489 SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548

Query: 1098 -PPGGKGPGQDRPPLGPT---VPYTEALQVFHHPVAQTPLHEKP-------YLPPPVSLF 1146
             PP    P   + P  PT    P T + +    P A TP   K         +PP V+  
Sbjct: 1549 IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP 1608

Query: 1147 SFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQ------------ 1194
            S +          P      A  +   +P S P  P SL  +P  P              
Sbjct: 1609 SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQA 1668

Query: 1195 ----PTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGF------------ 1238
                P    P  L    + P P + P    P+        SSA S               
Sbjct: 1669 SKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728

Query: 1239 ---------FLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPP 1289
                      LP+Q   +    G   SH P  K  LAP    S   +P T  + +  LP 
Sbjct: 1729 PLSTVAPAPLLPVQKDSSKTAKGKDASHSP--KGPLAP--PESKASTPLTAAAFEKVLPK 1784

Query: 1290 VAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGS 1349
                + S+AP+  PP++LP  P  + +L  P + Q  +PS    +  + S+ L    +  
Sbjct: 1785 PESASVSAAPS--PPVSLPLAPSPVPTL--PPK-QQFLPSSPGLVLESPSKPLAPADEDE 1839

Query: 1350 SATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGT- 1408
               +  P   EP S G       V+   P  +G+        PTP  + PVT    KG+ 
Sbjct: 1840 LLPLIPP---EPISGGVPFQSVLVNMPTPKSAGI------PVPTPSAKQPVT-KNNKGSG 1889

Query: 1409 --SLSSESILSLEGSSSTAGGSKRV-LSPAGSLELTMETQQQKRVKEEEASKADEKLELV 1465
              S S ES+  LE   ST   +++  L+ A  ++    ++ ++   E++A KA  KL L 
Sbjct: 1890 TESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLR 1949

Query: 1466 KPCSVVLTSTEDGK 1479
            +   V   +    K
Sbjct: 1950 QVTGVTRVTIRKSK 1963



 Score = 72.8 bits (177), Expect = 4e-12
 Identities = 121/516 (23%), Positives = 164/516 (31%), Gaps = 67/516 (12%)

Query: 1900 PQPPDAPASGTE---ATRGSSVSEAERLTASSCSMS-SQSMPGLPWLGPAPLGSVEKDTG 1955
            P P  AP        + +G ++   E  T S  ++   +  P  P    AP  S+   + 
Sbjct: 859  PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP 918

Query: 1956 SALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHV 2015
                  P     P SPS +    PP A   S     ++P        P A+ PSP G   
Sbjct: 919  KKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPA 978

Query: 2016 DPG-RGMGALPCGS-PRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWS 2073
             P  +G    P  + P  +  P T  P G    P             P  P+ SP     
Sbjct: 979  TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP----------AVTPPSPKGSPAATPF 1028

Query: 2074 PGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFP-----PAPLPHKLLSRSP 2128
            P  A +PP + PP     +  GSP+A     G    P    P     PA    K     P
Sbjct: 1029 PKGASTPPAATPP-----SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP 1083

Query: 2129 ETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTR 2188
                   K    +PS    P  P ++ P              + +   +  P      T 
Sbjct: 1084 AATPPSPKGGPATPSPKGAPMPPAATPP--------------SPKGGLATPPHKGAPTTP 1129

Query: 2189 APCPLIPIGGI-----QMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRW 2243
            A  P  P GG+     +     P A P   P P     +    G      A     +G  
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATP---PSPKGGLATPPPKGAPTTPAATPPSPKGGL 1186

Query: 2244 SPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTP 2303
            +      A  +P A     T  S   G   P  +    G P  P    P   G  A P+P
Sbjct: 1187 ATPSPKGAPTTPAA-----TPPSPKGGLATPSPK----GAPTTPAATPPSPKGGLATPSP 1237

Query: 2304 THSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPS-----ATPPLDRSSSVGCLA 2358
              +P TP  T P P  G     +  P   +P  P    PS     ATPP   + +   + 
Sbjct: 1238 KGAPTTPAATPPSPKGG----PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVT 1293

Query: 2359 EASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHP 2394
              S +    T    G P     +P PS  G P   P
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATP-PSPKGSPGTPP 1328



 Score = 72.8 bits (177), Expect = 4e-12
 Identities = 252/1153 (21%), Positives = 358/1153 (31%), Gaps = 188/1153 (16%)

Query: 498  ESPKSSLYREPL-----SSHSEKTKPEQSLLSLQHPPSTAPPVPL-LRSHSMPSAACT-- 549
            E+P  S+   P      ++ + K  P  S+ S     + A P P  + +   P  A T  
Sbjct: 884  ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP 943

Query: 550  ISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYSSEEPGPS 609
             +TP  P  G        T S   + +    T  P   K  PA   P G         PS
Sbjct: 944  AATPPSPKGGP------ATPSPKWAPTPPAAT--PPSPKGGPATPSPKGAPTPPAATPPS 995

Query: 610  SKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSEL 669
             K   + PS +  P    +T  + KG                                  
Sbjct: 996  PKGGPATPSPKGAPTPPAVTPPSPKGSPA------------------------------- 1024

Query: 670  QIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPA 729
              A P   G  T P A     +  P +             TPL K            P  
Sbjct: 1025 --ATPFPKGASTPPAATPPSPKGSPAA-------------TPLPKGAPTTPAATLPSPKG 1069

Query: 730  FESTKSQFGSPGPSDAARNLPLESTKSPAEPS-KSVPSLEGPTGFQPRTPKPGSGSESGK 788
              +T S  G+P P  A    P      PA PS K  P    P    P +PK G  +   K
Sbjct: 1070 GPATPSLKGAPTPPAAT---PPSPKGGPATPSPKGAPM---PPAATPPSPKGGLATPPHK 1123

Query: 789  ERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSP----------------- 831
               TT          +       L  P        P A  PSP                 
Sbjct: 1124 GAPTTPA-------ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1176

Query: 832  --PPAPHGRSAHSLQPKLVRQPNIQVPEI---LVTEEPDRPDTEPEPPPKEPEKTEEFQW 886
              PP+P G  A          P    P     L T  P    T P   P  P+       
Sbjct: 1177 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236

Query: 887  PQRSQT--LAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSV---PLSRSPSQESNVSLS 941
            P+ + T   A  P+ K  P     + A    ++   S +  +   P   +P+    V   
Sbjct: 1237 PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA--VVTP 1294

Query: 942  GSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSH 1001
             S +         G   AP+P +   P P G+     P   P       + +  SP  + 
Sbjct: 1295 PSPKGGPATSPPKG---APTPPAATPPSPKGSPGTPPPKGAP----TPPAVTPPSPKGTP 1347

Query: 1002 SAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEV 1061
            +   T   SK       S  GP+ PA  A P+    P           +   P       
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPTPPA--ATPSHKGGP---------AMTPPSPKRGPAIP 1396

Query: 1062 APKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGG--PPG------GKGPGQDRPPLGP 1113
            +PKG   S    P S K +  + +++  +A  S G   PP        K P    P  GP
Sbjct: 1397 SPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP 1456

Query: 1114 TVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLS 1173
              P ++       P    P  ++P  P  V+  S     +  P       +    + + S
Sbjct: 1457 ATPSSKGDPTL--PAVTPPSPKEPPAPKQVATSSSP---KKAPATPAPMGAPTLPAVIPS 1511

Query: 1174 SPYSMPPLPPSLFQ--APPLPL----QPTVLHPGQLHLPQLM--PHPANIPFRQPPSFLP 1225
            SP  +P  P S     AP   L     P  L P +  +P  M  P P   P    P   P
Sbjct: 1512 SPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAP 1571

Query: 1226 MPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAP--LATGSAGLSPSTEYSS 1283
                +  A S     P   + A   P   E  +P   TS +P    T  A   PS E   
Sbjct: 1572 ATPSSKEASSPPAVTPSTYKGA---PSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628

Query: 1284 DIRLPPVAPPASSSAPTSAP--PLALPACPDTMVSLVVPVRVQTNMPSYGSAMY---TTL 1338
                   A PA    PTS P  P +L   P +  S+   +       S G       T L
Sbjct: 1629 -------ATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTAL 1681

Query: 1339 SQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRV 1398
             ++LV  +  S+  +  P  + P +K ++     +       +G     S   P P    
Sbjct: 1682 KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP---- 1737

Query: 1399 PVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKA 1458
               LP +K +S +++     + +S +  G         S  LT    ++   K E AS +
Sbjct: 1738 --LLPVQKDSSKTAKG----KDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVS 1791

Query: 1459 DEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSD--PSDTKEIPPLP 1516
                    P S+ L  +     P K        G     +L S S    P+D  E+ PL 
Sbjct: 1792 AAP---SPPVSLPLAPSPVPTLPPKQQFLPSSPGL----VLESPSKPLAPADEDELLPLI 1844

Query: 1517 HPALSHGTAPGSEALKEYPQPSGK----PHRRGLTPLSVKKEDSKEQPDLPSLAPPSSLP 1572
             P    G  P    L   P P       P      P++   + S  + D     P     
Sbjct: 1845 PPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVP----E 1900

Query: 1573 LSETSSRPAKSQE 1585
            L E  S  A +Q+
Sbjct: 1901 LEEQDSTQATTQQ 1913



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 133/569 (23%), Positives = 187/569 (32%), Gaps = 97/569 (17%)

Query: 1877 PSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSM 1936
            PS +  P   P    A + P   P  P    + T   +G+  + A  L +     ++ S+
Sbjct: 1017 PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSL 1076

Query: 1937 PGLPWLGPAPLGSVEKDTGSALSYKPVSPRR-PWSPSKEAGSRPPLARKHSLTKNDSSPQ 1995
             G P    A                P SP+  P +PS +    PP A   S     ++P 
Sbjct: 1077 KGAPTPPAAT---------------PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121

Query: 1996 RCSPAREPQASAPSPPG-LHVDPGRGMGALPCGSPRLQLSPL-TLCPLGRELAPRAHVLS 2053
                   P A+ PSP G L   P +G    P  +P      L T  P G    P A   S
Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1181

Query: 2054 KLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVL 2113
               G   P  P+ +PT         +P  + P  K  LA P SP      P         
Sbjct: 1182 PKGGLATPS-PKGAPT---------TPAATPPSPKGGLATP-SPKGAPTTPAAT------ 1224

Query: 2114 FPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHP----LSSRPFSALHDFHGHILA 2169
             PP+P   K    +P    +P    +  PS   GPA P      + P +      G +  
Sbjct: 1225 -PPSP---KGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT 1280

Query: 2170 RTEENIFSHLPLHSQHLTRAPCPLI-----PIGGIQMVQARPGAHPTLLPGPTAAWVSGF 2224
                      P H      AP P +     P GG      +    P     P+     G 
Sbjct: 1281 ----------PPHKG----APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT 1326

Query: 2225 SGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGP 2284
                   T         + +PT  ++   +P +K    T SS+ EG   P       GGP
Sbjct: 1327 PPPKGAPTPPAVTPPSPKGTPTLPAT---TPSSKGGPTTPSSK-EGPTPPAATPSHKGGP 1382

Query: 2285 GRPPDWTPHGTGAPAEPTPTHSPCTP------PDTLPRPPQGRRAAQSWS-----PRLES 2333
               P   P     PA P+P   P +P      P   P  P  R  A + S     P   +
Sbjct: 1383 AMTP---PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT 1439

Query: 2334 P----RAPTNPEPS---ATPPLDRSSSVGCLAEASARFPARTRNL--SGEPRTRQDSPKP 2384
            P    +AP    P    ATP      ++  +   S + P   + +  S  P+    +P P
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499

Query: 2385 SGS--------GEPRAHPHQPEDRVPPNA 2405
             G+          P+  P  P  R  P A
Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPIA 1528



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 133/558 (23%), Positives = 186/558 (33%), Gaps = 48/558 (8%)

Query: 1877 PSSEAPPPGPPHALRADSSPILGPQPPDA----PASG--TEATRGSSVSEAERLTASSCS 1930
            P+  A  P  P    A  SP   P PP A    P  G  T   +G+  + A    +    
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139

Query: 1931 MSSQSMPGLPWLG----PAPLGSVE----KDTGSALSYKPVSPRRPWS-PSKEAGSRPPL 1981
            +++    G P       P+P G +     K   +  +  P SP+   + PS +     P 
Sbjct: 1140 LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199

Query: 1982 ARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPG-RGMGALPCGSPRLQLS-PLTLC 2039
            A   S     ++P        P A+ PSP G    P  +G    P  +P      P T  
Sbjct: 1200 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP 1259

Query: 2040 PLGRELAPRAHVLSKLEGTTDP---GLPRYSPTRRWSP--GQAESPPRSAPPGKWALAGP 2094
            P G    P A   S   G   P   G P  +     SP  G A SPP+ AP    A    
Sbjct: 1260 PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS 1319

Query: 2095 GSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSS 2154
               S G   P     P  + PP+P     L   P T  S  K    +PS   GP  P ++
Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTPPSPKGTPTL---PATTPSS-KGGPTTPSSKEGPTPPAAT 1375

Query: 2155 RPFSALHDFHGHILARTEENIFSHLPLHSQHLTR-APCPLIPIGGIQMVQARPGAHPTLL 2213
                      G  +          +P      T  A  PL P         R GA     
Sbjct: 1376 PSHKG-----GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSK 1430

Query: 2214 PGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDY 2273
               T   V+  S   +  T A +       S  + +  +V+P +         ++     
Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP-PAPKQVATSSS 1489

Query: 2274 PKERERTGGGPGRP--PDWTPHGTG-APAEPTPTHSPCTPPDTL----------PRPPQG 2320
            PK+   T    G P  P   P      PA P+    P  P  TL          P+    
Sbjct: 1490 PKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALI 1549

Query: 2321 RRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQD 2380
              A    SP+ ++P  PT  E  ATP    +SS   +  ++ +     + L   P     
Sbjct: 1550 PPAMTVPSPK-KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP 1608

Query: 2381 SPKPSGSGEPRAHPHQPE 2398
            SPK + +  P   P  PE
Sbjct: 1609 SPKEAPT-PPAVTPPSPE 1625



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 127/568 (22%), Positives = 180/568 (31%), Gaps = 100/568 (17%)

Query: 1877 PSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSC--SMSSQ 1934
            P  E P P          S +  P P + PA     T     + A  +T+SS   + ++ 
Sbjct: 881  PPKETPTP----------SVVNLPFPKEGPA-----TPAPKQAPALSMTSSSPKKARATP 925

Query: 1935 SMPGLPWLGPAPLGSVEKDTGSALSYK--PVSPRRPWSPSKEAGSRPPLARKHSLTKNDS 1992
            +  G+P   P+P G+      +  S K  P +P   W+P+      PP A   S     +
Sbjct: 926  APKGIP-ASPSPKGAPTPPAATPPSPKGGPATPSPKWAPT------PPAATPPSPKGGPA 978

Query: 1993 SPQRCSPAREPQASAPSPPGLHVDPG-RGMGALPCGSPRLQL-SPL-TLCPLGRELAPRA 2049
            +P        P A+ PSP G    P  +G    P  +P     SP  T  P G    P A
Sbjct: 979  TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAA 1038

Query: 2050 HVLSKLEGTTDPGLPRYSPTR--------RWSPGQ-----AESPPRSAPPGKWALAGPGS 2096
               S         LP+ +PT         +  P       A +PP + PP      GP +
Sbjct: 1039 TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP--KGGPAT 1096

Query: 2097 PSAGEHGPGLGLDPRVLFPPAPL------PHKLLSRSPETCASPWKAESRSPSCSPGPAH 2150
            PS     P     P    PP+P       PHK    +P       K    +P     P  
Sbjct: 1097 PS-----PKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151

Query: 2151 PLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQAR----- 2205
            P ++ P              + +   +  P      T A  P  P GG+     +     
Sbjct: 1152 PAATPP--------------SPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1197

Query: 2206 PGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERG-------RWSPTESSSASVSPV-- 2256
            P A P   P P     +    G      A     +G       + +PT  ++   SP   
Sbjct: 1198 PAATP---PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1254

Query: 2257 --------AKVSKFTLSSELEGG-DYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSP 2307
                    A          L+GG   P  +         PP        +P +  PT   
Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA 1314

Query: 2308 CTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPAR 2367
             TPP     P           P +  P     P   AT P  +       ++     PA 
Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA 1374

Query: 2368 TRNLSGEPRTRQDSPK-----PSGSGEP 2390
            T +  G P     SPK     PS  G+P
Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 238/1118 (21%), Positives = 373/1118 (33%), Gaps = 209/1118 (18%)

Query: 732  STKSQFGSPGP------SDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSE 785
            S  +  G PGP      S A +  PL S  + A P  S PS    T  +   P+  SG+ 
Sbjct: 33   SVTAALGQPGPTLPPPCSPAPQQCPL-SAANQASPFPS-PSTIASTPLEVPFPQSSSGTA 90

Query: 786  ----SGKERRTTSKE-ISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHG-RS 839
                +  E  T     I      ++   +  +  P+ L+G     A       APH  + 
Sbjct: 91   LPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPT-LKGTPSSSAPLALVALAPHSVQK 149

Query: 840  AHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAE 899
            + +  P L+  P    P + V E            P EP+             L ++P+E
Sbjct: 150  SSAFPPNLLTSP----PSVAVAESGSVITLSAPIAPSEPKTN-----------LNKVPSE 194

Query: 900  KLPPKKKRLR------------LAEMAQ-SSGESSFESSVP---LSRSPSQESNVSLSGS 943
             +P  K                +  MA   SG +S   + P   L+ +  Q  + ++S  
Sbjct: 195  VVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTIS-- 252

Query: 944  SRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPN---VS 1000
              S      + G      P S      L T  L      P     +++A   +P    +S
Sbjct: 253  --SVLISPQNPGSLSLKGPVSPPAALSLSTQSL------PVVTSSQKTAGPNTPPDFPIS 304

Query: 1001 HSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELE 1060
              +H+      SF  GS+ L G + P+ ++ P         K   V  +S      S+  
Sbjct: 305  LGSHLAPLHQSSF--GSVQLLGQTGPSALSDPTV-------KTISVDHSSTGASYPSQRS 355

Query: 1061 VAPKGRQESEE-PQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPY-- 1117
            V P     +E  P   ++ P    S+ +  S  +S    P G         L PT     
Sbjct: 356  VIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLIL 415

Query: 1118 -TEALQVFHHP-VAQTPLHEKPYLPPPVSLFSFQHLVQHEP---GQSPEFFSTQAMSSLL 1172
             +     +H+P VAQ P+      P          LV   P     +P   +T  +++ +
Sbjct: 416  KSSPNATYHYPLVAQMPVSSVGTTP----------LVVTNPCTIAAAPT--TTFEVATCV 463

Query: 1173 SSPYSMPPL-------PPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLP 1225
            S P S  P+       P +L  AP  P +P+      L +P   P P     +  PS + 
Sbjct: 464  SPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVL 523

Query: 1226 MPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDI 1285
            + +PT   L +   +P   + A   P        +  T L PL   +   SPS + +S  
Sbjct: 524  VKFPTQKDLQT---VPASLEGAPFSPAQAGLTTKKDPTVL-PLVQAAPKNSPSFQSTSSS 579

Query: 1286 RLPPVAPPASSSAPTSAPPLALPACPDTMVS--------LVVPVRVQTNMPSYGSAMYTT 1337
               P++P A+ +  +   PL +     +M S         V+         S G  + ++
Sbjct: 580  PEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSS 639

Query: 1338 L---------------SQILVTQSQGSS-----------ATVALPKFEEPPSKGTTV--- 1368
            L               + +  T ++G+S            TV+L     P  +GT     
Sbjct: 640  LITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLP 699

Query: 1369 ---CGADVHEVGPGPSG---------LSEEQSRAFPTPYLRVPVTLPERKGTSLSSESIL 1416
                 ++   V P P           L+ E  ++ P+P L    T P  K          
Sbjct: 700  LVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTK---------- 749

Query: 1417 SLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTE 1476
             ++G S T+      L+P  S      T +        +SK         P  + ++ + 
Sbjct: 750  KVDGISHTS-----ALAPVASSPKECPT-EDSGASATASSKGTLTYLADSPSPLGVSVSP 803

Query: 1477 DGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEY-- 1534
              KRP  +  G+ G        + +LSS P    E   LP  +LS   +  S A      
Sbjct: 804  QTKRP-PTKKGSAGPD----TPIGNLSS-PVSPVEASFLPENSLSFQGSKDSPATTHSPT 857

Query: 1535 -PQPSGKPHRRGLTPLSVK------KED----------SKEQPDLPSLAPPSSLPLSETS 1577
             P P G P    +TPLS K      KE            KE P  P  AP  +  LS TS
Sbjct: 858  PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP--APKQAPALSMTS 915

Query: 1578 SRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNP 1637
            S P K++     K +   PS               K      + +            + P
Sbjct: 916  SSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK------------WAP 963

Query: 1638 NLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPE 1697
              P  +  +      +       T   AT P P+ G   PS    P       P  V+P 
Sbjct: 964  TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAP------TPPAVTPP 1017

Query: 1698 GQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEG 1735
              K         +    P    P S +G PA   + +G
Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKG 1055



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 97/385 (25%), Positives = 148/385 (38%), Gaps = 65/385 (16%)

Query: 1055 PESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPT 1114
            P    E  P   QE  +PQ  ++     S+LS      T+  G PG   P    PP  P 
Sbjct: 2    PGEATETVPATEQELPQPQAETAVLPMSSALS-----VTAALGQPGPTLP----PPCSPA 52

Query: 1115 ---VPYTEALQVFHHP----VAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQA 1167
                P + A Q    P    +A TPL E P+  P  S  +   L     G +PE  +   
Sbjct: 53   PQQCPLSAANQASPFPSPSTIASTPL-EVPF--PQSSSGTALPL-----GTAPE--APTF 102

Query: 1168 MSSLLSSPYSMPPLPPSLFQAPPL---PLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFL 1224
            + +L+  P S    P +L  A P+    L+ T      L L  L PH        PP+ L
Sbjct: 103  LPNLIGPPIS----PAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLL 158

Query: 1225 PMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSD 1284
              P P+ +   SG  + L +  A   P + +++L ++ + + P   G+   SP    S+ 
Sbjct: 159  TSP-PSVAVAESGSVITLSAPIA---PSEPKTNLNKVPSEVVPNPKGTP--SPPCIVST- 211

Query: 1285 IRLPPVAPPAS---------SSAPTSAPPLALPACPDTMVSLVV-----PVRVQTNMPSY 1330
            +    V P AS          + PT+   +A P   DT +S V+     P  +    P  
Sbjct: 212  VPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVS 271

Query: 1331 GSAMYTTLSQIL--VTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVG-------PGPS 1381
              A  +  +Q L  VT SQ ++     P F  P S G+ +        G        GPS
Sbjct: 272  PPAALSLSTQSLPVVTSSQKTAGPNTPPDF--PISLGSHLAPLHQSSFGSVQLLGQTGPS 329

Query: 1382 GLSEEQSRAFPTPYLRVPVTLPERK 1406
             LS+   +     +     + P ++
Sbjct: 330  ALSDPTVKTISVDHSSTGASYPSQR 354



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 119/507 (23%), Positives = 186/507 (36%), Gaps = 82/507 (16%)

Query: 1877 PSSEAPPPGPPHALRADSSPILGP-QPPDAPASGTEATRGSSVSEAERLTASSCSMSSQS 1935
            P S    P  P      +SP + P  P  APA+       ++ S+ +    +   +S + 
Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445

Query: 1936 MPGL--PWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSS 1993
             P    P  GPA   S    T  A++  P SP+ P +P + A S              SS
Sbjct: 1446 APATSAPKGGPATPSSKGDPTLPAVT--PPSPKEPPAPKQVATS--------------SS 1489

Query: 1994 PQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRE----LAPRA 2049
            P++ +PA      AP+ P +     + + A P  S R  ++P T   L ++    LAP+ 
Sbjct: 1490 PKK-APATPAPMGAPTLPAVIPSSPKEVPATP-SSRRDPIAP-TATLLSKKTPATLAPKE 1546

Query: 2050 HVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLD 2109
             ++        P      PT + +P    S   S+PP        G+PS  E        
Sbjct: 1547 ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE-------- 1598

Query: 2110 PRVLFPPAPLPHKLLSRSPETCASPWKAESRSPS---CSPGPAHPLSSRPFSALHDFHGH 2166
              +L PPA     + S SP+   +P      SP     +P P    +S P +        
Sbjct: 1599 --LLIPPA-----VTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVT-------- 1643

Query: 2167 ILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSG 2226
                         P   +    +P  +    G  + QA  G       GPTA        
Sbjct: 1644 -------------PSSLKDSPTSPASVTCKMGATVPQASKGL--PAKKGPTAL-KEVLVA 1687

Query: 2227 GGSDLTGAREAQERGRWSPTESSSASVSPVA------KVSKFTLSSELEGGDYPKERERT 2280
               + T    A  R +   T+ SSA+  P+         SK  LS+       P +++ +
Sbjct: 1688 PAPESTPIITAPTR-KGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSS 1746

Query: 2281 GGGPGRPPDWTPHGTGAPAEPTPTHSPCTP---PDTLPRPPQGRRAAQSWSPRLESPRAP 2337
                G+    +P G  AP E +   +P T       LP+P     +A   SP +  P AP
Sbjct: 1747 KTAKGKDASHSPKGPLAPPE-SKASTPLTAAAFEKVLPKPESASVSAAP-SPPVSLPLAP 1804

Query: 2338 TNPEPSATPPLD-RSSSVGCLAEASAR 2363
             +P P+  P      SS G + E+ ++
Sbjct: 1805 -SPVPTLPPKQQFLPSSPGLVLESPSK 1830



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 127/558 (22%), Positives = 180/558 (32%), Gaps = 109/558 (19%)

Query: 1877 PSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSM 1936
            P   A P G        +S       P    + + A +   V E    T      +S++ 
Sbjct: 649  PLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENC 708

Query: 1937 PGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARK-------HSLTK 1989
            P    + P+P  +        L+  P  P+   SPS      PP  +K        +L  
Sbjct: 709  P----VAPSPQNTCAPLATLVLA--PEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAP 762

Query: 1990 NDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRA 2049
              SSP+ C P  +  ASA +         +G       SP          PLG  ++P+ 
Sbjct: 763  VASSPKEC-PTEDSGASATAS-------SKGTLTYLADSPS---------PLGVSVSPQT 805

Query: 2050 HVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLD 2109
                  +G+  P  P  + +   SP +A   P ++     +  G     A  H P     
Sbjct: 806  KRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS----LSFQGSKDSPATTHSPT---- 857

Query: 2110 PRVLFPP----APLPHKLLSRSPETCASPWKAESRSPSC------SPGPAHPLSSRPFSA 2159
                 PP    AP P  +   SP+    P K E+ +PS         GPA P   +  + 
Sbjct: 858  -----PPSPKGAPTPSAVTPLSPKGVTLPPK-ETPTPSVVNLPFPKEGPATPAPKQAPA- 910

Query: 2160 LHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAA 2219
                               L + S    +A     P G    + A P   P   P P AA
Sbjct: 911  -------------------LSMTSSSPKKARATPAPKG----IPASPS--PKGAPTPPAA 945

Query: 2220 WVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERER 2279
                  GG         A    +W+PT  ++   SP  K    T S +            
Sbjct: 946  TPPSPKGG--------PATPSPKWAPTPPAATPPSP--KGGPATPSPKGAPTPPAATPPS 995

Query: 2280 TGGGPGRPPDWTPHGTGAP---AEPTPTHSPC---------TPPDTLPRPPQGRRAAQSW 2327
              GGP  P   +P G   P     P+P  SP          TPP   P  P+G  AA   
Sbjct: 996  PKGGPATP---SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052

Query: 2328 SPRLESPRAPTNPEPS---ATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKP 2384
                 +  A T P P    ATP L  + +       S +    T +  G P     +P P
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP-P 1111

Query: 2385 SGSGEPRAHPHQPEDRVP 2402
            S  G     PH+     P
Sbjct: 1112 SPKGGLATPPHKGAPTTP 1129



 Score = 38.5 bits (88), Expect = 0.080
 Identities = 195/950 (20%), Positives = 295/950 (31%), Gaps = 97/950 (10%)

Query: 5    QSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAP-QPFPGPS 63
            +  + T   +G P     KG     + +   P  G  T + + +P      P  P  GP+
Sbjct: 919  KKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPA 978

Query: 64   SVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVD 123
            +   +G+          PK  P   S      P+   TP  ++P  P+    GS      
Sbjct: 979  TPSPKGAPTPPAATPPSPKGGPATPS------PKGAPTPPAVTPPSPK----GSP----- 1023

Query: 124  PMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRP----SQVSLK--PTE 177
               P P G+   P   P S    S A+   P+  P  P   +P P    +  SLK  PT 
Sbjct: 1024 AATPFPKGASTPPAATPPSPK-GSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP 1082

Query: 178  EAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYK 237
             A         P     +    P A      K   +    +  P  P       K  L  
Sbjct: 1083 PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT 1142

Query: 238  HRKSHAHRIKAGLA-SGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPA 296
                 A    A    S  GG   P        P      P  G +T S +    T   PA
Sbjct: 1143 PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTT---PA 1199

Query: 297  ELSPRPKQPLLS---SGLYSSGSHSSSHERCSLSQSS-----TAQSLEDPPPFVEPSSEH 348
               P PK  L +    G  ++ + +    +  L+  S     T  +   P P   P++  
Sbjct: 1200 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP 1259

Query: 349  PL-SHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKG--STESGYFSRSESAEQQVS 405
            P  +  P        K  L     K   +      P  KG  +T     + +  A    S
Sbjct: 1260 PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS 1319

Query: 406  P---PNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQ----PLLPLSTEDKPSLVPLSVPR 458
            P   P T     A           + T  L AT+      P  P S E      P + P 
Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP--PAATPS 1377

Query: 459  TQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHS--EKT 516
             +    +T         + + + D   P    LS +   ++P + + RE  ++ S  + T
Sbjct: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK---KAPATPVTREGAATPSKGDLT 1434

Query: 517  KPEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHS 576
             P  + +SL+  P+T+ P         P+   +   P  P     S  +     +  + S
Sbjct: 1435 PPAVTPVSLKKAPATSAP------KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSS 1488

Query: 577  SHVFTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDTASKPS---DEVEPKESELTKKTK 633
            S          K+ PA   P+G          S K+  + PS   D + P  + L+KKT 
Sbjct: 1489 SP---------KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP 1539

Query: 634  KGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHE 693
              L  K  +    +     KK       K+        A P S    + P    S  +  
Sbjct: 1540 ATLAPKEALIPPAMTVPSPKKTPAIPTPKE------APATPSSKEASSPPAVTPSTYKGA 1593

Query: 694  PWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFESTKSQFGSPGPSDAARNLPLES 753
            P  + +      T   +P  K            P    +T +  G+P       +   +S
Sbjct: 1594 PSPKELLIPPAVT---SPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDS 1650

Query: 754  TKSPA-----------EPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQH 802
              SPA           + SK +P+ +GPT  +     P   S       T          
Sbjct: 1651 PTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPES---TPIITAPTRKGPQTK 1707

Query: 803  TSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAP----HGRSAHSLQPKLVRQPNIQVPEI 858
             SS         PS   G   PL+     P  P      ++A         +  +  PE 
Sbjct: 1708 KSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPES 1767

Query: 859  LVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRL 908
              +        E   P  E         P  S  LA  P   LPPK++ L
Sbjct: 1768 KASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFL 1817



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 76/352 (21%), Positives = 120/352 (34%), Gaps = 46/352 (13%)

Query: 1867 EEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPP-DAPASGTEATRGSSVSEAERLT 1925
            E  +  +++  SS    P  P  + A + P + P  P + PA  T ++R   ++    L 
Sbjct: 1477 EPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPA--TPSSRRDPIAPTATLL 1534

Query: 1926 ASSCSM----------------SSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPW 1969
            +                     S +  P +P    AP     K+  S  +  P + +   
Sbjct: 1535 SKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG-- 1592

Query: 1970 SPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSP 2029
            +PS +    PP     S  +  + P    P+ E   + P+P G    P       P    
Sbjct: 1593 APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP-------PVTPS 1645

Query: 2030 RLQLSPLT----LCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAP 2085
             L+ SP +     C +G  +   +  L   +G T       +P    +P    +P R  P
Sbjct: 1646 SLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTP-IITAPTRKGP 1704

Query: 2086 PGKWALAGP----GSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRS 2141
              K + A        PSA     G    P     PAPL   L  +   +  +  K  S S
Sbjct: 1705 QTKKSSATSPPICPDPSAKNGSKG----PLSTVAPAPL---LPVQKDSSKTAKGKDASHS 1757

Query: 2142 PSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPL 2193
            P     P    +S P +A       +L + E    S  P     L  AP P+
Sbjct: 1758 PKGPLAPPESKASTPLTAA--AFEKVLPKPESASVSAAPSPPVSLPLAPSPV 1807



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 36/147 (24%), Positives = 48/147 (32%), Gaps = 31/147 (21%)

Query: 34   SVPYPGSGTAA-----------TQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPK 82
            ++P+P  G A            T  SP +    P P   P+S   +G+          PK
Sbjct: 892  NLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK 951

Query: 83   RPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQS 142
              P   S      P+   TP   +P  P+            P  P P G+   P   P S
Sbjct: 952  GGPATPS------PKWAPTPPAATPPSPKG----------GPATPSPKGAPTPPAATPPS 995

Query: 143  QLLPSHASIIP-PEDLPGVPKVFVPRP 168
               P      P P+  P  P V  P P
Sbjct: 996  ---PKGGPATPSPKGAPTPPAVTPPSP 1019


>gi|49087132 sal-like 2 [Homo sapiens]
          Length = 1007

 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 116/429 (27%), Positives = 171/429 (39%), Gaps = 103/429 (24%)

Query: 18  RKRLTKGEAIQTSVSSSVP--YPGSGTAATQESPAQELLAP-QPFPGPSSVLREGSQEKT 74
           R+ L  G   QT  + + P   PG+GTA++ + P   L +P +P     ++    S   +
Sbjct: 205 RQVLLLGSLGQTVGAPASPSELPGTGTASSTK-PLLPLFSPIKPVQTSKTLASSSSSSSS 263

Query: 75  GQQQKPPKRPPIEASVHI-----SQLP--------QHPLTPAFMSPGKPEHLLEGSTWQL 121
               + PK    +A  H+     SQ P         H  TPA      P   L GST QL
Sbjct: 264 SSGAETPK----QAFFHLYHPLGSQHPFSAGGVGRSHKPTPA------PSPALPGSTDQL 313

Query: 122 VDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPT----E 177
           +            +P L       PS   ++  + L G  +      S   LKP     E
Sbjct: 314 I-----------ASPHL-----AFPSTTGLLAAQCL-GAARGLEATASPGLLKPKNGSGE 356

Query: 178 EAHKKERKP-QKPG-KYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNL 235
            ++ +   P +KPG ++ C++C++     S LQ H+RSHTGERPY C  CG  F T+ NL
Sbjct: 357 LSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNL 416

Query: 236 YKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGES---------TDSEE 286
             H   H HR           E YPH ++M   P  E  +     S          +  E
Sbjct: 417 KVH--FHRHR-----------EKYPH-VQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAE 462

Query: 287 ETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSS 346
           E +AT G   E     ++PL++S    S + S +     LS S+   +    P F     
Sbjct: 463 EEAATPGGGVE-----RKPLVASTTALSATESLT----LLSTSAGTATAPGLPAF----- 508

Query: 347 EHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSP 406
                          + + ++  E K   DE     PGS+GS  SG    S +   Q+S 
Sbjct: 509 --------------NKFVLMKAVEPKNKADENT--PPGSEGSAISGVAESSTATRMQLSK 552

Query: 407 PNTNAKSYA 415
             T+  S+A
Sbjct: 553 LVTSLPSWA 561



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 20/49 (40%), Positives = 25/49 (51%)

Query: 194 CQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242
           C  C R  + P  L+ H   H GERP+ C  CG +F T+ NL  H   H
Sbjct: 633 CVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGH 681



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 61/249 (24%), Positives = 86/249 (34%), Gaps = 41/249 (16%)

Query: 1766 PSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHS-------------KKCQE 1812
            P  L+ H   H   RP+ CK C  AF T+GNL  H      S             KK   
Sbjct: 643  PRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTN 702

Query: 1813 TGVLEE----------------LEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSD 1856
               L++                L    G + +   +     G+ +  + Q       +  
Sbjct: 703  AVTLQQHVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEEL 762

Query: 1857 SDLDEDEDEDEEE---SQDELSRPSSEAPPPGPPHAL--RADSSPILGPQPPDAPASGTE 1911
            S+ +E+EDE+EEE    +D L+   SE+   G   A+  R DS    G +  +       
Sbjct: 763  SEEEEEEDEEEEEDVTDEDSLAGRGSES---GGEKAISVRGDSEEASGAE-EEVGTVAAA 818

Query: 1912 ATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKP---VSPRRP 1968
            AT G  +   E+ T  S          L    P   GS     G     KP    SP   
Sbjct: 819  ATAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASA 878

Query: 1969 WSPSKEAGS 1977
             +P  EA S
Sbjct: 879  LTPEGEATS 887



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 20/49 (40%), Positives = 26/49 (53%)

Query: 1752 GKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800
            G++ C  C       S L+ H+R+HT  RPY C  C   F T+GNL  H
Sbjct: 371  GRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVH 419



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 40/136 (29%), Positives = 58/136 (42%), Gaps = 21/136 (15%)

Query: 1811 QETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDE----- 1865
            +E    EE E EE   D   +DS    GSE+  E   S   DS+  S  +E+        
Sbjct: 760  EELSEEEEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVAAAA 819

Query: 1866 ---DEEESQDELSRPSSEAPPPGP-----PHALRADSSPILG-------PQPPDAPASG- 1909
                E +S ++ ++ SS  PPP P     P  +   SS +LG       P+   +PAS  
Sbjct: 820  TAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASAL 879

Query: 1910 TEATRGSSVSEAERLT 1925
            T     +SV+  E L+
Sbjct: 880  TPEGEATSVTLVEELS 895



 Score = 38.9 bits (89), Expect = 0.062
 Identities = 109/442 (24%), Positives = 159/442 (35%), Gaps = 78/442 (17%)

Query: 507 EPLSSHSEKTKP--EQSLLSLQHPPSTAPPVPLLRS-HSMPSAACTISTPHHPFRGSYSF 563
           EP +   E T P  E S +S     STA  + L +   S+PS A  + T H    GS+ F
Sbjct: 518 EPKNKADENTPPGSEGSAISGVAESSTATRMQLSKLVTSLPSWA--LLTNHFKSTGSFPF 575

Query: 564 DDHITDSEALSHSSHVFTSHPRMLKRQPAIELP--LGGEYSSEEPGPSSKDTASKPSDEV 621
              +    A    +         + RQ A+ +     G  ++  P PSS   +S P+  V
Sbjct: 576 PYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSS-ASSGPNQCV 634

Query: 622 E-------PKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKP 674
                   P+   L      G +     ++C +CG  +  R N  AH   +      A P
Sbjct: 635 ICLRVLSCPRALRLHYGQHGGERP----FKCKVCGRAFSTRGNLRAHFVGH-----KASP 685

Query: 675 ISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFESTK 734
            +   ++ P  +K         Q +   LG  +   P       +  G  +E  + +ST 
Sbjct: 686 AARAQNSCPICQKKFTNAVTLQQHVRMHLGGQI---PNGGTALPEGGGAAQENGSEQSTV 742

Query: 735 SQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTS 794
           S  GS     + +  P E      E        E            G GSESG E     
Sbjct: 743 SGAGSFPQQQSQQPSPEEELSEEEEEEDE----EEEEDVTDEDSLAGRGSESGGE----- 793

Query: 795 KEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQ 854
           K ISV        + DS E+ SG E E   +A       A  G+   S   K  +Q ++ 
Sbjct: 794 KAISV--------RGDS-EEASGAEEEVGTVA-----AAATAGKEMDS-NEKTTQQSSL- 837

Query: 855 VPEILVTEEPDRPDTEPEPPPKEPEKT------EEFQWPQRSQTLAQLPAEKLPPK---- 904
                    P  PD+  +P P E   +      EE   P+RS +    PA  L P+    
Sbjct: 838 -------PPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSS----PASALTPEGEAT 886

Query: 905 ----KKRLRLAE-MAQSSGESS 921
                + L L E M +  GESS
Sbjct: 887 SVTLVEELSLQEAMRKEPGESS 908



 Score = 38.9 bits (89), Expect = 0.062
 Identities = 41/158 (25%), Positives = 66/158 (41%), Gaps = 13/158 (8%)

Query: 1659 KETYTMATAPHPEAGRLVPSSSRKPRMTEVHLP----SLVSPEG-QKDLARVEKEEERRG 1713
            +E  T+A A    AG+ + S+ +  + + +  P    SL  P+  ++  + V   +E  G
Sbjct: 810  EEVGTVAAAA--TAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGG 867

Query: 1714 EPEEDA-PASQ---RGEPARIKIFEGGYKSNEEYVYVRGRGRGKYVCEECGIRCKKPSML 1769
            +PE  + PAS     GE   + + E      E      G    +  CE CG      + L
Sbjct: 868  KPERSSSPASALTPEGEATSVTLVEE-LSLQEAMRKEPGESSSRKACEVCGQAFPSQAAL 926

Query: 1770 KKHIRTHTDVRP-YVCKHCHFAFKTKGNLTKHMKSKAH 1806
            ++H +TH    P + C  C   F  +  L KHM    H
Sbjct: 927  EEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHH 964



 Score = 36.6 bits (83), Expect = 0.31
 Identities = 23/99 (23%), Positives = 41/99 (41%), Gaps = 5/99 (5%)

Query: 154 PEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPG----KYICQYCSRPCAKPSVLQK 209
           PE          P     S+   EE   +E   ++PG    +  C+ C +     + L++
Sbjct: 869 PERSSSPASALTPEGEATSVTLVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEE 928

Query: 210 HIRSHTGERP-YPCGPCGFSFKTKSNLYKHRKSHAHRIK 247
           H ++H  E P + C  C   F  ++ L KH     H+++
Sbjct: 929 HQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQ 967



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 60/260 (23%), Positives = 92/260 (35%), Gaps = 55/260 (21%)

Query: 2057 GTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPP 2116
            G++ P  P + P RR              PG + +A  G+ + G  G             
Sbjct: 103  GSSVPTDPTWGPERRGEES----------PGHFLVAATGTAAGGGGG------------- 139

Query: 2117 APLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEE-NI 2175
                  L+  SP+  A+P   ES     +P P  P    P   +   H +I    EE  +
Sbjct: 140  ------LILASPKLGATPLPPES-----TPAPPPPPPPPPPPGVGSGHLNIPLILEELRV 188

Query: 2176 FSHLPLHSQHLTRAPC-PLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGA 2234
                 +H   +T   C  ++ +G +      P A P+ LPG      +G +     L   
Sbjct: 189  LQQRQIHQMQMTEQICRQVLLLGSLGQTVGAP-ASPSELPG------TGTASSTKPLLPL 241

Query: 2235 REAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGP-GRPPDWTPH 2293
                +  + S T +SS+S S           S   G + PK+       P G    ++  
Sbjct: 242  FSPIKPVQTSKTLASSSSSS-----------SSSSGAETPKQAFFHLYHPLGSQHPFSAG 290

Query: 2294 GTGAPAEPTPTHSPCTPPDT 2313
            G G   +PTP  SP  P  T
Sbjct: 291  GVGRSHKPTPAPSPALPGST 310


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 355/1711 (20%), Positives = 570/1711 (33%), Gaps = 320/1711 (18%)

Query: 482  DSVKPRR-----SSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVP 536
            +S  PRR     S   +  S    K   +R P      K+K ++   S     ST P   
Sbjct: 201  ESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSR----STTPAPK 256

Query: 537  LLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELP 596
              R+H   SA    S+                 S + S S+   T    +  R P+    
Sbjct: 257  SRRAHRSTSADSASSSD---------------TSRSRSRSAAAKTHTTALAGRSPSPASG 301

Query: 597  LGGEYSS--EEPG------PSSKDTASK-PSDEVEPKESELTKKTKKGLKTKGVIYECNI 647
              GE  +   EPG      PSS +TA+K PS   E K+ +  +K+               
Sbjct: 302  RRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSAT------------- 348

Query: 648  CGARYKKRDNYEAHKKYYCSELQIAKPISAGTHT-SPEA-EKSQIEHEPWSQMMHYKLGT 705
                   R +    +     E     P+ A  H  SP+    + +  EP        +  
Sbjct: 349  -------RPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEP--------VNP 393

Query: 706  TLELTPLRKRRKEKS-------LGDEEEPPAFESTK------SQFGSPGPSDAA------ 746
              E +P R R   KS          E  PP+ + TK      S   SP P+ A       
Sbjct: 394  PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREI 453

Query: 747  RNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSF 806
             + P    +S     +       P+    R+  P +        RT +K       +  +
Sbjct: 454  SSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQW 513

Query: 807  EKSDSLEQ-PSGLEGEDKPLAQFPSPP---------------PAPHGRSAHSLQPKLVRQ 850
             +S S ++       + +  ++ P  P                A  GRS HS  P    +
Sbjct: 514  RRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRS-HSRSPATRGR 572

Query: 851  PNIQVPEILV---TEEPDRPDTEPEPPPKEPEK--TEEFQWPQRSQTLAQLPAEKLPPKK 905
               + P       +  P R  +    P +   +  T   +   RS+T A+  +    P +
Sbjct: 573  SRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVR 632

Query: 906  KRLRLAEMAQSSGESSFESSVPLSRSPSQ----------ESNVSLSGSSRSASFERDDHG 955
            +R R    A+ SG S   +     RS S+           +    SG SRS +  R    
Sbjct: 633  RRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRS 692

Query: 956  KAEAP-------------SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVS-- 1000
            ++  P               S    P+  G    +    +      RRS S  SP +   
Sbjct: 693  RSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKS 752

Query: 1001 -----HSAHMTETRSKSFDYGSL--SLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSR 1053
                  S  ++  RSK+    SL  SL+G S   P        PP R +       S S 
Sbjct: 753  RISSRRSRSLSSPRSKAKSRLSLRRSLSGSS---PCPKQKSQTPPRRSR-------SGSS 802

Query: 1054 PPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGP 1113
             P+++    P+  + S  P P   K  +K+   Q  S+++ H     G  P Q       
Sbjct: 803  QPKAKSRTPPRRSRSSSSPPP---KQKSKTPSRQSHSSSSPHPKVKSGTPPRQGS----- 854

Query: 1114 TVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAM--SSL 1171
                          +     +E+   P   S F        E    PE  S      S  
Sbjct: 855  --------------ITSPQANEQSVTPQRRSCF--------ESSPDPELKSRTPSRHSCS 892

Query: 1172 LSSP----YSMPPLPPSLFQAPPLPLQPTVLHPGQL-HLPQLMPHPANIPFRQPPSFLPM 1226
             SSP     S PP       + P P    ++ P Q  H     P P+ +  R  P     
Sbjct: 893  GSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRS 952

Query: 1227 PYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIR 1286
              P S+  S    LP  S      P        ++K    P  + S  +SP  +  +   
Sbjct: 953  VSPCSNVESR--LLPRYSHSGSSSPDT------KVKPETPPRQSHSGSISPYPKVKAQTP 1004

Query: 1287 LPPVAPPASSSAPTSAPPLAL-PACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQ 1345
              P    + S  P      +L  +CP    SL +   V+++ P  G + +   S  L  Q
Sbjct: 1005 PGPSLSGSKSPCPQEKSKDSLVQSCPG---SLSLCAGVKSSTPP-GESYFGVSSLQLKGQ 1060

Query: 1346 SQGS--------SATVALPKFEEP---------PSKGTTVCGADVHEVGPGPSGLSEEQS 1388
            SQ S        S  V     E P         P  G +   + V E+    S + +++ 
Sbjct: 1061 SQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELA-SRSPIRQDRG 1119

Query: 1389 RAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQK 1448
                +P L+  ++ PE+      S S  +++ S+S  G S+        LE T E++++ 
Sbjct: 1120 EFSASPMLKSGMS-PEQSRFQSDSSSYPTVD-SNSLLGQSR--------LE-TAESKEKM 1168

Query: 1449 RVKEEEASKADEKLELVK----------PCSVVLTSTEDGKRPEKSHLGNQGQGRRELEM 1498
             +  +E + A    +  K            S+V   T      E+S  G+  + + +   
Sbjct: 1169 ALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSA 1228

Query: 1499 LSSLSSDPSDTKEIPPLPHPA---LSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKED 1555
            L + S D    + +     PA   LSH ++   E      + S +   R    L++ +  
Sbjct: 1229 LPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQ 1288

Query: 1556 SK---EQPDLPSLA-----PPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWC 1607
            S+   E  ++PS+A     P  S    E S+ P +        +      L T  N  + 
Sbjct: 1289 SQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFS 1348

Query: 1608 ----------YLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKV 1657
                      +LN ++ +       +S+  +G   S  +P+      KA +S   S Q +
Sbjct: 1349 SEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPD---AVEKAGMS---SNQSI 1402

Query: 1658 SKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEE 1717
            S        +P  +A    PS  R          S  SPE +  L R      R G    
Sbjct: 1403 S--------SPVLDAVPRTPSRERSS--------SASSPEMKDGLPRTPSRRSRSGSSPG 1446

Query: 1718 DAPASQRGEPARIKIFEGGYKSNEEYVYVRGRGRG--------KYVCEECGIRCKKPSML 1769
                S  G P+R  +  G     ++      RGR         K + +    R + PS  
Sbjct: 1447 LRDGS--GTPSRHSL-SGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSP 1503

Query: 1770 KKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDL 1829
            + + +  T  R           KT        +S++ S   QE  V      +E +  D 
Sbjct: 1504 ELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSS--QELDVKPSASPQERSESDS 1561

Query: 1830 FQDSEGREGSEAVEEHQFSDLEDSDSDSDLD----------EDEDEDE-----EESQDEL 1874
              DS+ +  +   +  +     + DS S L           E +D+       +   D  
Sbjct: 1562 SPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSS 1621

Query: 1875 SRPSSEAPPPGPPHALRADSSPILGPQP---------PDAPASGTEATRGSSVSEAERLT 1925
              P + AP   P  +    SS   GP P         P+ P     A RGS  S   +  
Sbjct: 1622 PEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTK 1681

Query: 1926 ASSCSM--SSQSMPGLPWLGPAPLGSVEKDTGSALSYKP-VSPRRPWSPSKEAGSRPPLA 1982
            + +     SS+S P L     A L    +   S+   +    PR   SPS  +      +
Sbjct: 1682 SRTPPRRRSSRSSPELT--RKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKS 1739

Query: 1983 RKHSLTKNDSSPQRCSPAREPQASAPSPPGL 2013
            R     ++ SSP+  + +R  ++ +P P GL
Sbjct: 1740 RSSRRRRSASSPRTKTTSRRGRSPSPKPRGL 1770



 Score = 69.7 bits (169), Expect = 3e-11
 Identities = 230/1093 (21%), Positives = 360/1093 (32%), Gaps = 216/1093 (19%)

Query: 16   SPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTG 75
            SPR +     +++ S+S S P P                  Q    P    R GS +   
Sbjct: 764  SPRSKAKSRLSLRRSLSGSSPCP-----------------KQKSQTPPRRSRSGSSQPKA 806

Query: 76   QQQKPPKR-------PPIEASV------HISQLPQHPLTPAFMSPGKPEHLLEGSTWQLV 122
            + + PP+R       PP + S       H S  P HP   +   P +       +  Q V
Sbjct: 807  KSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSP-HPKVKSGTPPRQGSITSPQANEQSV 865

Query: 123  DPMR-------PGPSGSFVAPGLHPQSQLLPSHA-SIIPPEDLPG-----VPKVFV---- 165
             P R       P P      P  H  S   P    S  PP   P       PKV      
Sbjct: 866  TPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISP 925

Query: 166  ----------PRPSQVSLKPTEEAHKKER-----KPQKPGKYICQYCSRPCAKPSVLQKH 210
                      P PS+V+ + T    +        + +   +Y     S P  K       
Sbjct: 926  RQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPP 985

Query: 211  IRSHTGE-RPYPC-------GPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMG------- 255
             +SH+G   PYP        GP     K+     K + S        L+   G       
Sbjct: 986  RQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPP 1045

Query: 256  GEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPA-----ELSPRPKQPLLSSG 310
            GE Y  G+   ++ G+    P     T S E   + S  P+     + SP+  +   SS 
Sbjct: 1046 GESY-FGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSP 1104

Query: 311  LYSSGSHSS-SHERCSLSQSSTAQSLEDPPP--FVEPSSEHPLSHKPEDTHTIKQKLALR 367
            +    S S    +R   S S   +S   P    F   SS +P      D++++  +  L 
Sbjct: 1105 VTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTV----DSNSLLGQSRLE 1160

Query: 368  LSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQ 427
             +E K     +    P  + +T S         + + SP     +  + ++F    R   
Sbjct: 1161 TAESK-----EKMALPPQEDATAS-----PPRQKDKFSPFPVQDRPESSLVFKDTLRTPP 1210

Query: 428  RTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPR 487
            R      +S +      T+++ S +P S    +++E           VV+ SE    +P 
Sbjct: 1211 RERSGAGSSPE------TKEQNSALPTSSQDEELME-----------VVEKSE----EPA 1249

Query: 488  RSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAA 547
               LS  SS     S+   E  SS   + +P  SL +L    S A     L +  +PS A
Sbjct: 1250 GQILSHLSSELKEMSTSNFE--SSPEVEERPAVSL-TLDQSQSQAS----LEAVEVPSMA 1302

Query: 548  CTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYSSEEPG 607
             +   PH                         F+   + L   P  E   G        G
Sbjct: 1303 SSWGGPH-------------------------FSPEHKELSNSPLRENSFGSPLEFRNSG 1337

Query: 608  PSSKDTASKPSDEVE-----PKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHK 662
            P   +  +  S EV+     P  ++L       +K +         G    +       K
Sbjct: 1338 PLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQST----RSSGHSSSELSPDAVEK 1393

Query: 663  KYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLG 722
                S   I+ P+      +P  E+S     P       ++   L  TP R+ R   S G
Sbjct: 1394 AGMSSNQSISSPVLDAVPRTPSRERSSSASSP-------EMKDGLPRTPSRRSRSGSSPG 1446

Query: 723  --DEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPS-KSVPSLEGPTGFQPRTP- 778
              D    P+  S      SPG  D  R      ++  + P  K++P    P    P +P 
Sbjct: 1447 LRDGSGTPSRHSLSGS--SPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPE 1504

Query: 779  ---------KPGSGSESGKERRT-------------TSKEISVIQHTSSFEKSDSLEQPS 816
                     +  SGSES  +++T             +S+E+ V    S  E+S+S   P 
Sbjct: 1505 LNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPD 1564

Query: 817  GLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVR---QPNIQVPEILVTEEPDRPDTEPEP 873
                   PL Q      +P   S   L P+  R    P ++             D+ PEP
Sbjct: 1565 SKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEP 1624

Query: 874  PPKEPE---------KTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFES 924
                P           + + + P    + +   + + PPK +  R    ++SS E   +S
Sbjct: 1625 KAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRG--SRSSPEPKTKS 1682

Query: 925  SVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPH 984
              P    P + S+ S    +R A   R     + +P   S   P+   +  ++ P     
Sbjct: 1683 RTP----PRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEK 1738

Query: 985  AREMRRSASEQSP 997
            +R  RR  S  SP
Sbjct: 1739 SRSSRRRRSASSP 1751



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 129/543 (23%), Positives = 192/543 (35%), Gaps = 124/543 (22%)

Query: 604  EEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKK 663
            E P P S    S  S    PK+ +  KK  +G +++          +  ++     + KK
Sbjct: 166  EPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSE---------SSSPRRERKKSSKKK 216

Query: 664  YYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGD 723
             + SE +  K      H SP  +  +   +        K   +   TP  K R+      
Sbjct: 217  KHRSESESKK----RKHRSPTPKSKRKSKDK-------KRKRSRSTTPAPKSRR------ 259

Query: 724  EEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSG 783
                 A  ST +   S   SD +R+            S+S  +    T    R+P P SG
Sbjct: 260  -----AHRSTSAD--SASSSDTSRS-----------RSRSAAAKTHTTALAGRSPSPASG 301

Query: 784  ---------SESG--KERRTTSKEISVIQHTSSFEKSD------SLEQPSGLEGEDKPLA 826
                     SE G    +R +S E +  Q +S +E  D      S  +PS          
Sbjct: 302  RRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGP 361

Query: 827  QFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEP-----PPKEPEKT 881
            + P+P P    R   S QP L   P        +++EP  P +E  P     PPK PEK 
Sbjct: 362  EPPAPTPLLAERHGGSPQP-LATTP--------LSQEPVNPPSEASPTRDRSPPKSPEKL 412

Query: 882  EEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLS 941
                 PQ S       +E  PP  +  +++  A SS ES   +      +P     +S S
Sbjct: 413  -----PQSSS------SESSPPSPQPTKVSRHASSSPESPKPAP-----APGSHREISSS 456

Query: 942  GSSRSASFERDDHGKAEAPSPSSDM------RPKPLGTHMLTVPSHHPHAR----EMRRS 991
             +S++ S  R    K+ + +PS  M           G      P+   H+R    + RRS
Sbjct: 457  PTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRS 516

Query: 992  ASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASL 1051
             S Q    S S      RS+S          P  P      +R    +RR     R  S 
Sbjct: 517  RSAQRWGRSRSP-QRRGRSRS----------PQRPG----WSRSRNTQRRG----RSRSA 557

Query: 1052 SRPPESELEVAPKGRQESEEP----QPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQD 1107
             R        A +GR  S  P    +  S  P+ + S S+  +   S    P  +G  + 
Sbjct: 558  RRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRS 617

Query: 1108 RPP 1110
            R P
Sbjct: 618  RTP 620



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 139/597 (23%), Positives = 199/597 (33%), Gaps = 109/597 (18%)

Query: 1838 GSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPI 1897
            GS    + Q S L  S  D +L E  ++ EE +   LS  SSE       +    +SSP 
Sbjct: 1217 GSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNF---ESSPE 1273

Query: 1898 LGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSA 1957
            +  +P          T   S S+A        SM+S       W GP             
Sbjct: 1274 VEERP------AVSLTLDQSQSQASLEAVEVPSMASS------WGGP------------- 1308

Query: 1958 LSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDP 2017
              + P       SP +E     PL  ++S           S   +   + P    L  DP
Sbjct: 1309 -HFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDP 1367

Query: 2018 GRGM---GALPCGSPRLQLSPLTLCPLGR-----------ELAPRAHVLSKLEGTTDP-- 2061
               M        G    +LSP  +   G            +  PR     +    + P  
Sbjct: 1368 SLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEM 1427

Query: 2062 --GLPRYSPTRRWSPGQAES-PPRSAPPGKWALAG--------PGSPSAGEHGPGLGLDP 2110
              GLPR +P+RR   G +      S  P + +L+G        P +PS G        +P
Sbjct: 1428 KDGLPR-TPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEP 1486

Query: 2111 RVLFPPAPLPHKLLSRSPET---CASPWKAESRSPSCSPGPA---HPLSSRPFS-ALHDF 2163
            + L P  P P      SPE    C +P +  S S S          PL  R  S +  + 
Sbjct: 1487 KAL-PQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQEL 1545

Query: 2164 HGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSG 2223
                 A  +E   S     S+  TR P            ++R G+ P +         S 
Sbjct: 1546 DVKPSASPQERSESDSSPDSKAKTRTPL---------RQRSRSGSSPEVDSK------SR 1590

Query: 2224 FSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGG 2283
             S   S    + E +++ R +P   S +  SP  K               P+        
Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRA--------LPRRSRSGSSS 1642

Query: 2284 PGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPS 2343
             GR P  +P G+ +  E +P H           PP+ R A      R  S  +P     S
Sbjct: 1643 KGRGP--SPEGSSS-TESSPEH-----------PPKSRTA------RRGSRSSPEPKTKS 1682

Query: 2344 ATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDR 2400
             TPP  RSS         AR   R+R+ S  P TR  +P P     P     +P ++
Sbjct: 1683 RTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTP-PRHRRSPSVSSPEPAEK 1738



 Score = 55.8 bits (133), Expect = 5e-07
 Identities = 71/268 (26%), Positives = 104/268 (38%), Gaps = 31/268 (11%)

Query: 871  PEPPPKEPEKTEEFQWPQRSQTLAQLPAEKL-PPKKKRLRLAEMAQSSGESS--FESSVP 927
            P   P +   T E + P  S  + Q P++ L PP + + R    +  S +S      + P
Sbjct: 2410 PPSAPSQSRMTSE-RAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTP 2468

Query: 928  LSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPS---SDMRPKPL--GTHMLTVPSHH 982
            ++ S S  S    + +S +     D +G    P+P    SD+   P   G    +  +  
Sbjct: 2469 VAGSQSLSSGAVATTTSSAG----DHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAAL 2524

Query: 983  PHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPA---RVAPPE 1039
              A+E RRS+S  S + S S+  + + S S   GS S     +  PV P     RV  P 
Sbjct: 2525 QPAKE-RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583

Query: 1040 RRKCFLVRQASLSRPPE-----------SELEVAPKGRQESEEPQPSSSKPSAKSSLSQI 1088
                  VR+    RPPE           S    +      S     SSS  S+ SS S  
Sbjct: 2584 PAPKEAVREG---RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2640

Query: 1089 SSAATSHGGPPGGKGPGQDRPPLGPTVP 1116
            SS+++S    P   GP     P  P  P
Sbjct: 2641 SSSSSSSSPSPAKPGPQALPKPASPKKP 2668



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 84/338 (24%), Positives = 116/338 (34%), Gaps = 73/338 (21%)

Query: 743  SDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQH 802
            S A  +  + S  +P  P   V      TG Q   P   +  +  KERR++S   S    
Sbjct: 2485 SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQ--PSALAALQPAKERRSSSSSSSSSSS 2542

Query: 803  TSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTE 862
            +SS   S S    SG    D   +  P  P                        E+ +  
Sbjct: 2543 SSSSSSSSSSSSSSGSSSSDSEGSSLPVQP------------------------EVALKR 2578

Query: 863  EPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSF 922
             P      P P PKE  +                P E  P K+KR   +  + SS  SS 
Sbjct: 2579 VPS-----PTPAPKEAVREGR-------------PPEPTPAKRKRRSSSSSSSSSSSSSS 2620

Query: 923  ESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHH 982
             SS   S S S  S+ S S SS S+S          +PSP+   +P P        P   
Sbjct: 2621 SSSSSSSSSSSSSSSSSSSSSSSSSS---------SSPSPA---KPGPQALPKPASPKKP 2668

Query: 983  PHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRK 1042
            P     RRS S + P  S    + ++RS S+     S      P+P   P         +
Sbjct: 2669 PPGE--RRSRSPRKPIDS----LRDSRSLSY-----SPVERRRPSPQPSPRDQQSSSSER 2717

Query: 1043 CFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS 1080
                 Q   SR P      + K R+E+  P+P   + S
Sbjct: 2718 GSRRGQRGDSRSP------SHKRRRETPSPRPMRHRSS 2749



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 78/325 (24%), Positives = 118/325 (36%), Gaps = 57/325 (17%)

Query: 863  EPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSF 922
            +P R   E + P  EP K        R  + ++ P  K   KKK+       +  G  S 
Sbjct: 152  DPQRRAREAKQPAPEPPKPYSLV---RESSSSRSPTPKQKKKKKK-------KDRGRRS- 200

Query: 923  ESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHH 982
            ESS P  R   ++S+      S S S +R    K  +P+P S  + K          +  
Sbjct: 201  ESSSP--RRERKKSSKKKKHRSESESKKR----KHRSPTPKSKRKSKDKKRKRSRSTTPA 254

Query: 983  PHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRK 1042
            P +R   RS S  S + S ++  + +RS +    + +L G S P+P +            
Sbjct: 255  PKSRRAHRSTSADSASSSDTSR-SRSRSAAAKTHTTALAGRS-PSPAS------------ 300

Query: 1043 CFLVRQASLSRPPESELEVAPKGR---QESEEPQPSSSKPSAKSSLSQISSAATSHGGPP 1099
                      R  E +   +  G    Q    P+ ++ +PS+            S   P 
Sbjct: 301  ---------GRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRP- 350

Query: 1100 GGKGPGQDRPPLGPTVPYTEALQVFHH-----PVAQTPLHEKPYLPPPVSLFSFQHLVQH 1154
                P  +R   GP  P    L    H     P+A TPL ++P  PP  +          
Sbjct: 351  ---SPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEA----SPTRDR 403

Query: 1155 EPGQSPEFFSTQAMSSLLSSPYSMP 1179
             P +SPE    Q+ SS  S P   P
Sbjct: 404  SPPKSPEKL-PQSSSSESSPPSPQP 427



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 139/624 (22%), Positives = 224/624 (35%), Gaps = 102/624 (16%)

Query: 1809 KCQETGVLEELEAEEGTSDDLFQDSEGR--EG-SEAVEEHQFSDLEDSDSDSDLDEDEDE 1865
            +C+  G+LE L +   T   + Q + G   +G    + +HQ + + ++ + S +      
Sbjct: 2129 RCRSPGMLEPLGSSR-TPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRI------ 2181

Query: 1866 DEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLT 1925
                +   +S  ++  PP      L A  S +  P P  +  +   A   S +  A   +
Sbjct: 2182 --ALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAA---S 2236

Query: 1926 ASSCSMSSQSMPGLPWL----------GPAPLGSVEKDTGSALSYKPVS-PRRPWSPSKE 1974
            A++ +++S   P +P              A +      T  A S   ++ PR P +P+  
Sbjct: 2237 AAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVN 2296

Query: 1975 -AGSRPPLARKH-SLTKNDSSPQRC---SPAREPQASAPSPPGLHVDPGRGMGALPCGSP 2029
             AG+R P A    SLT + + P      S +R PQA  P+   L V P       P    
Sbjct: 2297 LAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQA--PASANL-VGPRSAHATAPVNIA 2353

Query: 2030 RLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTR---RWSPGQAESPPRSAPP 2086
              + +   L P     A  A  LS     T P +P  +  R   R SP   +      PP
Sbjct: 2354 GSRTAA-ALAPASLTSARMAPALSGAN-LTSPRVPLSAYERVSGRTSPPLLDRARSRTPP 2411

Query: 2087 GKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSP-ETCASPWKAESRSPSCS 2145
                     +PS            R+    AP P   + ++P ++   P + + RSP  S
Sbjct: 2412 S--------APSQS----------RMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPS 2453

Query: 2146 PGPAHP----LSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQM 2201
                        + P +         +A T  +   H  + S      P P +P   +  
Sbjct: 2454 AFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLS-----VPAPGVPHSDVGE 2508

Query: 2202 VQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSK 2261
              A  GA     P   AA               R +      S + SSS+S S  +  S 
Sbjct: 2509 PPASTGAQQ---PSALAALQPAKE---------RRSSSSSSSSSSSSSSSSSSSSSSSSS 2556

Query: 2262 FTLSSELEGGDYPKERERTGGGPGRPPDWTPH-----GTGAPAEPTPTHSPCTPPDTLPR 2316
             + SS+ EG   P + E       R P  TP        G P EPTP             
Sbjct: 2557 GSSSSDSEGSSLPVQPE---VALKRVPSPTPAPKEAVREGRPPEPTPA------------ 2601

Query: 2317 PPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPR 2376
              + RR++ S S    S  + ++   S++     SSS    + +S+  P+  +    +  
Sbjct: 2602 -KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP-GPQAL 2659

Query: 2377 TRQDSPKPSGSGEPRAH-PHQPED 2399
             +  SPK    GE R+  P +P D
Sbjct: 2660 PKPASPKKPPPGERRSRSPRKPID 2683



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 265/1375 (19%), Positives = 446/1375 (32%), Gaps = 197/1375 (14%)

Query: 276  PTEGEST-DSEEETSATSGHPAELSPRPKQPLLSSGLYS-----SGSHSSSHERC----- 324
            P+ G S  DS  E  A    P   S  P  P L++   +     SGS SS  ++      
Sbjct: 1473 PSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTP 1532

Query: 325  --SLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTIKQKLALRL-SERKKVIDEQAFL 381
                S+S ++Q L D  P   P         P+     +  L  R  S     +D ++ L
Sbjct: 1533 LGQRSRSGSSQEL-DVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRL 1591

Query: 382  SPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLL 441
            SP           SRS S+ +    P                R   R    + +S +P  
Sbjct: 1592 SPRR---------SRSGSSPEVKDKP----------------RAAPRAQSGSDSSPEPKA 1626

Query: 442  PLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRSSMESPK 501
            P          P ++PR       +K    +     ++E     P +S  +RR S  SP+
Sbjct: 1627 P---------APRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPE 1677

Query: 502  -SSLYREPLSSHSEKTKPE---QSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHHPF 557
              +  R P    S ++ PE   ++ LS +   +++ P    R+      + ++S+P  P 
Sbjct: 1678 PKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPE-PA 1736

Query: 558  RGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDTASKP 617
              S S       S     +S   T       R P+ + P G + S      S ++     
Sbjct: 1737 EKSRS-------SRRRRSASSPRTKTTSRRGRSPSPK-PRGLQRSRSR---SRREKTRTT 1785

Query: 618  SDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKPISA 677
                    S+ T + ++  +++  +      G+ Y  R           S  +  +  S 
Sbjct: 1786 RRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGR--SR 1843

Query: 678  GTHTSPEAEKSQIEHEPWSQMMHYKLGTT----LELTPLRKRRKEKSLGDEEEPPAFEST 733
               TS +  +S+    PW +        T       TPL  RR+ +S      P +   +
Sbjct: 1844 TPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRS---RTSPVSRRRS 1900

Query: 734  KSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGK--ERR 791
            +S+         +R  P+   +S    S++ P     +  +  T +  S S +     RR
Sbjct: 1901 RSRTSVTRRRSRSRASPVSRRRSR---SRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRR 1957

Query: 792  TTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPS---PPPAPHGRSAHSLQPKLV 848
            + S+   V +  S    S    + S       P+ +  S     P    RS     P   
Sbjct: 1958 SRSRTPPVTRRRSRSRTSPITRRRS--RSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTR 2015

Query: 849  RQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAE---KLPPKK 905
            R+   + P  +      R    P  P K           +RS++     A     L    
Sbjct: 2016 RRSRSRTPPAIRRRSRSRT---PLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSP 2072

Query: 906  KRLRLAEMAQSSGESSFESSVPLSR--SPSQESNVSLSGSSRSASFERDDHGKAEAPSPS 963
              +R    + SS + S  ++ P +R  S S+   V+L+ SSR + F R            
Sbjct: 2073 PAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALN-SSRMSCFSRPSMSPTPLDRCR 2131

Query: 964  SDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGP 1023
            S    +PLG+    +         M      + P+   ++ + E  ++S    +L+LT  
Sbjct: 2132 SPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTS-VPENHAQSRI--ALALTAI 2188

Query: 1024 SAPAPVAPPARVAPPERRKCFLVRQASLSRP-PESELEVAPKGRQESEEPQPSSSKPSAK 1082
            S      PP+  A          R + +  P P   L  AP     S  P  S++  +  
Sbjct: 2189 SLGTARPPPSMSAAG-----LAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLA 2243

Query: 1083 S--------------SLSQISSAATSHGGP-----PGGKGPGQDRPPLGPTVPYT----- 1118
            S              S +  ++AA +   P     P        R P  P V        
Sbjct: 2244 SARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTP 2303

Query: 1119 EALQVFHHPVAQTP--------LHEKPYLPPPVSLFSFQHLVQHEP----------GQSP 1160
             AL       + TP            P  P   +L   +      P            +P
Sbjct: 2304 AALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAP 2363

Query: 1161 EFFSTQAMSSLLSSP-YSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQ 1219
               ++  M+  LS    + P +P S ++       P +L   +   P   P  + +   +
Sbjct: 2364 ASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSER 2423

Query: 1220 PPSFLPMPYPTS---SALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLA----TGS 1272
             PS      P+S    A S     P Q Q    +P         +     P+A      S
Sbjct: 2424 APS------PSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSS 2477

Query: 1273 AGLSPSTEYSSDIR-LPPVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYG 1331
              ++ +T  + D   +  V  P    +    PP +  A   + ++ + P + + +  S  
Sbjct: 2478 GAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSS 2537

Query: 1332 SAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAF 1391
            S+  ++ S    + S  SS + +             V    V    P P     E     
Sbjct: 2538 SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE 2597

Query: 1392 PTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVK 1451
            PTP  R   +      +S SS S  S   SSS++  S    S                  
Sbjct: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------------------ 2639

Query: 1452 EEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEML---SSLSSDPSD 1508
               +S +       KP    L      K+P      ++   R+ ++ L    SLS  P +
Sbjct: 2640 -SSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSP-RKPIDSLRDSRSLSYSPVE 2697

Query: 1509 TKEIPPLPHPALSHGT---------------APGSEALKEYPQPSGKPHRRGLTP 1548
             +   P P P     +               +P  +  +E P P    HR   +P
Sbjct: 2698 RRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 148/691 (21%), Positives = 219/691 (31%), Gaps = 118/691 (17%)

Query: 1764 KKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQETGVLEELEAEE 1823
            KK S  KKH R+ ++ +    +      K K    K  +S++ +   +         A+ 
Sbjct: 210  KKSSKKKKH-RSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADS 268

Query: 1824 GTSDDLFQDSEGREGSEAVEEHQ--FSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEA 1881
             +S D    S  R  S A + H    +    S +     E +    E       RPSS  
Sbjct: 269  ASSSDT---SRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSS-- 323

Query: 1882 PPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPW 1941
                P  A +  SSP    +  D       ATR S   E         S   +     P 
Sbjct: 324  ----PETATKQPSSPY---EDKDKDKKEKSATRPSPSPERS-------STGPEPPAPTPL 369

Query: 1942 LGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAG---SRPPLARKHSLTKNDSSPQRCS 1998
            L     GS +    + LS +PV+P    SP+++     S   L +  S   +  SPQ   
Sbjct: 370  LAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTK 429

Query: 1999 PAREPQASAPSP-----PGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLS 2053
             +R   +S  SP     PG H    R + + P    R           GR    ++H   
Sbjct: 430  VSRHASSSPESPKPAPAPGSH----REISSSPTSKNRSH---------GRAKRDKSH--- 473

Query: 2054 KLEGTTDPGLPRYSPTRRWSPGQAESP-------PRSAPPGKWALAGPGSP----SAGEH 2102
                        ++P+RR   G++ SP        RS  P K   +   SP    S    
Sbjct: 474  -----------SHTPSRRM--GRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQ 520

Query: 2103 GPGLGLDPRVLFPPAPLPHKLLSRSPE----TCASPWKAESRSPSCSPGPAHPLS----S 2154
              G    P+          +  SRSP+    + +   +   RS S   G +H  S     
Sbjct: 521  RWGRSRSPQ---------RRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRG 571

Query: 2155 RPFSALHDFHGHILART--EENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTL 2212
            R  S      G   +RT       S  P   +  +R P            + R      +
Sbjct: 572  RSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPV 631

Query: 2213 LPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGD 2272
                 +   +  SG     T AR  + R R       S S +P  +  +    +    G 
Sbjct: 632  RRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGR 691

Query: 2273 YPKERERTGGG-------PGRPPDWTPHGTGAPAEPTPTHSPC----------TPPDTLP 2315
                  R G          GR    TP   G     +   +            + P+   
Sbjct: 692  SRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKK 751

Query: 2316 RPPQGRRAAQSWSPRLE-----------SPRAPTNPEPSATPPLDRSSSVGCLAEASARF 2364
                 RR+    SPR +           S  +P   + S TPP  RS S     +A +R 
Sbjct: 752  SRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPP-RRSRSGSSQPKAKSRT 810

Query: 2365 PARTRNLSGEPRTRQDSPKPSGSGEPRAHPH 2395
            P R    S  P  +Q S  PS      + PH
Sbjct: 811  PPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH 841



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 50/204 (24%), Positives = 70/204 (34%), Gaps = 22/204 (10%)

Query: 1831 QDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHAL 1890
            + S     S +      S    S S      D +      Q E++     +P P P  A+
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590

Query: 1891 RADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSV 1950
            R    P   P      +S + ++  SS S +   ++SS S SS S         +     
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650

Query: 1951 EKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSP 2010
                G     KP SP++P  P  E  SR P  RK   +  DS     SP  E +  +P P
Sbjct: 2651 PAKPGPQALPKPASPKKP--PPGERRSRSP--RKPIDSLRDSRSLSYSPV-ERRRPSPQP 2705

Query: 2011 PGLHVDPGRGMGALPCGSPRLQLS 2034
                             SPR Q S
Sbjct: 2706 -----------------SPRDQQS 2712



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 113/518 (21%), Positives = 175/518 (33%), Gaps = 65/518 (12%)

Query: 1908 SGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKP---VS 1964
            S T   RG S S +ER   S  S         P +  + + S    + S+   K    +S
Sbjct: 715  SRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLS 774

Query: 1965 PRRPWS---PSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGM 2021
             RR  S   P  +  S+ P  R  S +    +  R  P R   +S+P P      P R  
Sbjct: 775  LRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQS 834

Query: 2022 GALPCGSPRLQLSP-----LTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQ 2076
             +     P+++            P   E +      S  E + DP L   +P+R    G 
Sbjct: 835  HSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGS 894

Query: 2077 AESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWK 2136
            +    +S+ P + + +   SP            P+V    A +  +  S S  +  SP +
Sbjct: 895  SPPRVKSSTPPRQSPSRSSSP-----------QPKV---KAIISPRQRSHSGSSSPSPSR 940

Query: 2137 AESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPI 2196
              SR+         P  SR  S   +    +L R     +SH    S      P      
Sbjct: 941  VTSRTT--------PRRSRSVSPCSNVESRLLPR-----YSHSGSSSPDTKVKP------ 981

Query: 2197 GGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGARE--AQERGRWSPTESSSASVS 2254
                    R     ++ P P    V   +  G  L+G++    QE+ + S  +S   S+S
Sbjct: 982  ----ETPPRQSHSGSISPYPK---VKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLS 1034

Query: 2255 PVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTL 2314
              A V   T   E   G    + +   G     PD     +      + + SP     + 
Sbjct: 1035 LCAGVKSSTPPGESYFGVSSLQLK---GQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQ 1091

Query: 2315 PRPPQGRRAAQSWSPRL--ESPRAPTNPEPSATPPL--DRSSSVGCLAEASARFPARTRN 2370
              P  GR  + S    L   SP      E SA+P L    S         S+ +P    N
Sbjct: 1092 TSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSN 1151

Query: 2371 -LSGEPRTRQDSPKPSGSGEPR----AHPHQPEDRVPP 2403
             L G+ R      K   +  P+    A P + +D+  P
Sbjct: 1152 SLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSP 1189



 Score = 40.0 bits (92), Expect = 0.028
 Identities = 66/291 (22%), Positives = 97/291 (33%), Gaps = 31/291 (10%)

Query: 1877 PSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSM 1936
            P ++  P  P  +  +D S  L  Q    P +G+++    +V+           M S   
Sbjct: 2441 PPAQDQPRSPVPSAFSDQSRCLIAQT--TPVAGSQSLSSGAVATTTSSAGDHNGMLSVPA 2498

Query: 1937 PGLPW--LGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSP 1994
            PG+P   +G  P  +  +   +  + +P   RR  S S  + S    +   S + + S  
Sbjct: 2499 PGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGS 2558

Query: 1995 -----QRCSPAREPQAS---APSP---PGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGR 2043
                 +  S   +P+ +    PSP   P   V  GR     P    R   S         
Sbjct: 2559 SSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSS-------SS 2611

Query: 2044 ELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHG 2103
              +  +   S    ++       S +   S   + S P  A PG  AL  P SP     G
Sbjct: 2612 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG 2671

Query: 2104 PGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSS 2154
                  PR        P   L  S     SP   E R PS  P P    SS
Sbjct: 2672 ERRSRSPR-------KPIDSLRDSRSLSYSP--VERRRPSPQPSPRDQQSS 2713



 Score = 37.4 bits (85), Expect = 0.18
 Identities = 57/241 (23%), Positives = 79/241 (32%), Gaps = 20/241 (8%)

Query: 1497 EMLSSLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQP-------SGKPHRRGLTPL 1549
            E  SS S  P   K+         S  ++P  E  K   +        S K   R  TP 
Sbjct: 176  ESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPK 235

Query: 1550 SVKKEDSKEQPDLPSL--APPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWC 1607
            S +K   K++    S   AP S      TS+  A S + + S+        HTT      
Sbjct: 236  SKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG-- 293

Query: 1608 YLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATA 1667
                  P   +  +  +        S   P+ P  +TK   S    K K  KE      +
Sbjct: 294  --RSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPS 351

Query: 1668 PHPEAGRLVPS-SSRKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGE 1726
            P PE     P   +  P + E H  S       + LA     +E    P E +P   R  
Sbjct: 352  PSPERSSTGPEPPAPTPLLAERHGGS------PQPLATTPLSQEPVNPPSEASPTRDRSP 405

Query: 1727 P 1727
            P
Sbjct: 406  P 406



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 128/636 (20%), Positives = 193/636 (30%), Gaps = 113/636 (17%)

Query: 1796 NLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSE---------------GREGSE 1840
            ++  H + +    +C E   LEE+  E+G  +   Q+                 G+E + 
Sbjct: 56   DILDHERKRRVELRCLE---LEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETP 112

Query: 1841 A-----VEEHQFSDLEDSDSD------SDLDEDEDEDEEESQDELSRPSSEAPPPGPPHA 1889
                   E HQ ++L +  ++         D   D    + Q         AP P  P++
Sbjct: 113  GQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYS 172

Query: 1890 LRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGS 1949
            L  +SS    P P        +     S S + R      S   +               
Sbjct: 173  LVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESE-------SK 225

Query: 1950 VEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDS-SPQRCSPAREPQASAP 2008
              K        K  S  +    S+     P   R H  T  DS S    S +R   A+A 
Sbjct: 226  KRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAK 285

Query: 2009 SPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSP 2068
            +    H     G    P    R           G   AP +       GTT    P    
Sbjct: 286  T----HTTALAGRSPSPASGRR-----------GEGDAPFSE-----PGTTSTQRPSSPE 325

Query: 2069 TRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSP 2128
            T    P             K A     SP     GP          PPAP          
Sbjct: 326  TATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPE---------PPAP---------- 366

Query: 2129 ETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTR 2188
                +P  AE    S  P    PLS  P +   +       R+       LP  S   + 
Sbjct: 367  ----TPLLAERHGGSPQPLATTPLSQEPVNPPSE-ASPTRDRSPPKSPEKLPQSSSSESS 421

Query: 2189 APCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTES 2248
             P P  P    +   + P + P   P P         G   +++ +  ++ R        
Sbjct: 422  PPSPQ-PTKVSRHASSSPES-PKPAPAP---------GSHREISSSPTSKNRSHGRAKRD 470

Query: 2249 SSASVSPVAKVSKFTLSSELEGGDYPKERERT----GGGPGRPPDWTPHGTG-------A 2297
             S S +P  ++ +    +  + G   + R RT    G    R P W    +        +
Sbjct: 471  KSHSHTPSRRMGRSRSPATAKRG---RSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRS 527

Query: 2298 PAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCL 2357
            P     + SP  P  +  R  Q R  ++S      + R  ++    AT    RS +    
Sbjct: 528  PQRRGRSRSPQRPGWSRSRNTQRRGRSRS------ARRGRSHSRSPATRGRSRSRTPARR 581

Query: 2358 AEASARFPARTRNLSGEP-RTRQDSPKPSGSGEPRA 2392
              + +R PAR R+ S  P R R  S  P+  G  R+
Sbjct: 582  GRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRS 617



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 32/132 (24%), Positives = 45/132 (34%), Gaps = 22/132 (16%)

Query: 2274 PKERERTGGGPG----RPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSP 2329
            P   ER GG P      P    P    + A PT   SP   P+ LP+      +  S  P
Sbjct: 368  PLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQP 427

Query: 2330 RLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGE 2389
               S  A ++PE     P                 P   R +S  P ++  S     +  
Sbjct: 428  TKVSRHASSSPESPKPAPA----------------PGSHREISSSPTSKNRS--HGRAKR 469

Query: 2390 PRAHPHQPEDRV 2401
             ++H H P  R+
Sbjct: 470  DKSHSHTPSRRM 481



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 31/135 (22%), Positives = 47/135 (34%)

Query: 274  EEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQ 333
            ++P+   +    +E  ++S   +  S        SS   SSGS SS  E  SL       
Sbjct: 2516 QQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVA 2575

Query: 334  SLEDPPPFVEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGY 393
                P P   P         PE T   +++ +   S         +  S  S  S+ S  
Sbjct: 2576 LKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2635

Query: 394  FSRSESAEQQVSPPN 408
             S S S+    S P+
Sbjct: 2636 SSSSSSSSSSSSSPS 2650



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 43/168 (25%), Positives = 60/168 (35%), Gaps = 17/168 (10%)

Query: 2234 AREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPH 2293
            +R A          SS  S S     +  T ++ L G        R G G     +    
Sbjct: 257  SRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTT 316

Query: 2294 GTGAPAEP-TPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSS 2352
             T  P+ P T T  P +P +   +  + + A +   P     R+ T PEP A  PL    
Sbjct: 317  STQRPSSPETATKQPSSPYEDKDKDKKEKSATR---PSPSPERSSTGPEPPAPTPL---- 369

Query: 2353 SVGCLAE--ASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPE 2398
                LAE    +  P  T  LS EP    + P  +     R+ P  PE
Sbjct: 370  ----LAERHGGSPQPLATTPLSQEP---VNPPSEASPTRDRSPPKSPE 410



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 35/137 (25%), Positives = 54/137 (39%), Gaps = 23/137 (16%)

Query: 3    PEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGP 62
            P+++V+  +  E +P KR  +  +  +S SSS     S ++++  S +    +       
Sbjct: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSS---SSSSSSSSSSSSSSSSSSSSSSSSS 2642

Query: 63   SSVLREGSQEKTGQQQKP----PKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGS- 117
            SS     S  K G Q  P    PK+PP             P      SP KP   L  S 
Sbjct: 2643 SSSSSSPSPAKPGPQALPKPASPKKPP-------------PGERRSRSPRKPIDSLRDSR 2689

Query: 118  --TWQLVDPMRPGPSGS 132
              ++  V+  RP P  S
Sbjct: 2690 SLSYSPVERRRPSPQPS 2706


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
            sapiens]
          Length = 1560

 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 126/516 (24%), Positives = 177/516 (34%), Gaps = 111/516 (21%)

Query: 815  PSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPD--TEPE 872
            P+   GE  P+      P AP   S     P  ++QP  Q P    T +   P   T P+
Sbjct: 608  PAAATGEAAPVLTVQPAPQAPPAVSTPL--PLGLQQPQAQQPPQAPTPQAAAPPQATTPQ 665

Query: 873  PPP---KEPEKTEEFQWPQRSQT--LAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVP 927
            P P     PEK    Q P  + T  L Q   +   P+++  +   ++      S  +SV 
Sbjct: 666  PSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQ--PLSAEGPHLSVPASVI 723

Query: 928  LSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHARE 987
            +S  P  +     +  ++ A           +P+P+  +                P A  
Sbjct: 724  VSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQI----------------PAAAP 767

Query: 988  MRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVR 1047
            ++      SP++ H A + ++                +P P  PP+R  PP R +     
Sbjct: 768  LKGPGPSSSPSLPHQAPLGDSPHLP------------SPHPTRPPSR--PPSRPQ----- 808

Query: 1048 QASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGP--- 1104
              S+SRPP             SE P      P A  +L  I       G PP    P   
Sbjct: 809  --SVSRPP-------------SEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPT 853

Query: 1105 --GQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVS---LFSFQHLVQHEPGQS 1159
              G  +PPL P     E            PL   P+LPP  +   + S        P  +
Sbjct: 854  APGPPQPPLRPQSQPPEG-----------PLPPAPHLPPSSTSSAVASSSETSSRLPAPT 902

Query: 1160 PEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQ 1219
            P  F  Q   S    P+  P  PP+L                      L+P PA  P   
Sbjct: 903  PSDFQLQFPPS--QGPHKSPTPPPTL---------------------HLVPEPAAPPPPP 939

Query: 1220 PPSF----LPMP-YPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAG 1274
            P +F     P P  P   AL   F   + S   LQ         PQ  TSL PL + +A 
Sbjct: 940  PRTFQMVTTPFPALPQPKALLERFH-QVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAAS 998

Query: 1275 LSPSTEYSSDI-RLPPVAPPASSSAPTSAPPLALPA 1309
            +  S +  S     P  AP  +  A T  PPL LPA
Sbjct: 999  VLVSGQAPSGTPTAPSHAPAPAPMAATGLPPL-LPA 1033



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 129/557 (23%), Positives = 198/557 (35%), Gaps = 110/557 (19%)

Query: 1089 SSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKP--YLPP----- 1141
            + AA++  G P G+ P    P LG + P   A  V  H    TP+  KP   LPP     
Sbjct: 310  AGAASAPTGTPSGQ-PLAVAPGLGSS-PLVPAPNVILHRTP-TPIQPKPAGVLPPKLYQL 366

Query: 1142 ---PVSLFSFQHLVQHEPGQSPE----------FFSTQAMSSLLSSPYSMPPLPPSLFQA 1188
               P +       +Q EPG  P+            + +A  +++ S +  P L  ++F+ 
Sbjct: 367  TPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQ 426

Query: 1189 PPL------PLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPL 1242
            PP       P QP    PG L  P  + H  N               +S  + +   LP 
Sbjct: 427  PPATTTGAAPPQP----PGALSKPMSV-HLLN-------------QGSSIVIPAQHMLPG 468

Query: 1243 QSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSA 1302
            Q+QF L  PG     LPQ  ++L     G    + +      +   P+    + + P S 
Sbjct: 469  QNQFLL--PGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSL 526

Query: 1303 PPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQ----GSSATVALPKF 1358
             P+  P        ++    +Q   P+      +  +  L TQSQ    G +AT  L   
Sbjct: 527  GPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGV 586

Query: 1359 EEPPS-----------------KGTTVCGADVHEVGPGPS-----------GLSEEQSR- 1389
              PPS                    T   A V  V P P            GL + Q++ 
Sbjct: 587  TLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQ 646

Query: 1390 --AFPTPYLRVP--VTLPE-RKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMET 1444
                PTP    P   T P+   G + S E I+  +  S+T       +    SL++ +  
Sbjct: 647  PPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSAT----PTAILTQDSLQMFLPQ 702

Query: 1445 QQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSS 1504
            ++ ++    E         L  P SV++++    + P  +    +G G       S  S 
Sbjct: 703  ERSQQPLSAEGP------HLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQAS- 755

Query: 1505 DPSDTKEIP---------PLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKED 1555
             P+   +IP         P   P+L H    G       P P+  P R    P SV +  
Sbjct: 756  -PAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPP 814

Query: 1556 SKEQPDLPSLAPPSSLP 1572
            S  +P L    PP + P
Sbjct: 815  S--EPPLHPCPPPQAPP 829



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 129/524 (24%), Positives = 173/524 (33%), Gaps = 130/524 (24%)

Query: 1884 PGPPHALRADSSPILGPQP-PDAP-ASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPW 1941
            P  P A   +++P+L  QP P AP A  T    G    +A++                P 
Sbjct: 605  PATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQ----------------PP 648

Query: 1942 LGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAR 2001
              P P  +       A + +P SP    SP K    +PP A   ++   DS        R
Sbjct: 649  QAPTPQAAAPPQ---ATTPQP-SPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQER 704

Query: 2002 EPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDP 2061
              Q  +   P L V     + A P   P    +P T    G  L P+A            
Sbjct: 705  SQQPLSAEGPHLSVPASVIVSAPP---PAQDPAPATPVAKGAGLGPQA------------ 749

Query: 2062 GLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPG---SPSAGEHGPGLGLDPRVLFPPAP 2118
                  P  + SP  A   P +AP     L GPG   SPS     P LG  P +   P+P
Sbjct: 750  ------PDSQASPAPAPQIPAAAP-----LKGPGPSSSPSLPHQAP-LGDSPHL---PSP 794

Query: 2119 LPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSH 2178
             P +  SR P          SR  S S  P+ P                           
Sbjct: 795  HPTRPPSRPP----------SRPQSVSRPPSEP--------------------------- 817

Query: 2179 LPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLL-PGPTAAWVSGFSGGGSDLTGAREA 2237
             PLH     +AP P +P  GI ++Q + G  P    P PTA       G        +  
Sbjct: 818  -PLHPCPPPQAP-PTLP--GIFVIQNQLGVPPPASNPAPTAP------GPPQPPLRPQSQ 867

Query: 2238 QERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGA 2297
               G   P      S +  A  S    SS L     P + +        PP   PH +  
Sbjct: 868  PPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPT-PSDFQLQF-----PPSQGPHKS-- 919

Query: 2298 PAEPTPTH---SPCTPPDTLPRPPQGRRAAQSWSPRLESPRA--------PT-----NPE 2341
            P  P   H    P  PP   P PP+  +   +  P L  P+A        P+     N  
Sbjct: 920  PTPPPTLHLVPEPAAPP---PPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKA 976

Query: 2342 PSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPS 2385
              A      S+S+G L   +A      +  SG P     +P P+
Sbjct: 977  GGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPA 1020



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 178/794 (22%), Positives = 272/794 (34%), Gaps = 143/794 (18%)

Query: 735  SQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESG----KER 790
            S FG  G + A    P     + A    S P +  P     RTP P     +G    K  
Sbjct: 305  SVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLY 364

Query: 791  RTTSKEISVIQHTSSFEKSDSL--EQP----------SGLEGEDKPLAQFPSPPPAPHGR 838
            + T K  +    T + +       +QP          +G  G++  L+ FP+P       
Sbjct: 365  QLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAP------- 417

Query: 839  SAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTE--------EFQWPQRS 890
               +LQ  + +QP    P       P +P      P       +        +   P ++
Sbjct: 418  ---ALQANVFKQP----PATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQN 470

Query: 891  Q-TLAQLPAEKLPPKKKRLR-------LAEMAQSSGESSFESSVPLSRSPSQESNVSLSG 942
            Q  L   PA +LP +   L        LA  A  +G     +  P+  + +    +SL  
Sbjct: 471  QFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIAN--PILTNQNLAGPLSLGP 528

Query: 943  SSRSASFERDDHGKAEAP----SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPN 998
                 S     H  + AP     P+    P  L    L   S    A     +  +    
Sbjct: 529  VLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTL 588

Query: 999  VSHSAHMTETRSKSFDYGS-LSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPES 1057
               +  M  T        +  + TG +AP     PA  APP           ++S P   
Sbjct: 589  PPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPP-----------AVSTPLPL 637

Query: 1058 ELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPY 1117
             L+  P+ +Q  + P P ++ P   ++       A+S    P     GQ  P   PT   
Sbjct: 638  GLQ-QPQAQQPPQAPTPQAAAPPQATTPQPSPGLASS----PEKIVLGQP-PSATPTAIL 691

Query: 1118 T-EALQVF-HHPVAQTPLH-EKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLL-- 1172
            T ++LQ+F     +Q PL  E P+L  P S+     +    P Q P   +  A  + L  
Sbjct: 692  TQDSLQMFLPQERSQQPLSAEGPHLSVPASVI----VSAPPPAQDPAPATPVAKGAGLGP 747

Query: 1173 ------SSPYSMPPLPPSL-FQAPPLPLQPTVLHPGQL----HLPQLMPHPANIPFRQP- 1220
                  +SP   P +P +   + P     P++ H   L    HLP   PHP   P R P 
Sbjct: 748  QAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS--PHPTRPPSRPPS 805

Query: 1221 -----------PSFLPMPYPTSSALSSGFFL--------PLQSQFALQLPGDVESHL-PQ 1260
                       P   P P P +     G F+        P  S  A   PG  +  L PQ
Sbjct: 806  RPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQ 865

Query: 1261 IKTSLAPL--------ATGSAGLSPSTEYSSDIRLPPVA------PPASSSAPTSAPPLA 1306
             +    PL        ++ S+ ++ S+E SS +  P  +      PP+     +  PP  
Sbjct: 866  SQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPT 925

Query: 1307 LPACPDTMVSLVVPVR----VQTNMPS--YGSAMYTTLSQI---LVTQSQGSSATVALPK 1357
            L   P+       P R    V T  P+     A+     Q+   ++ Q++   A  A   
Sbjct: 926  LHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAP-- 983

Query: 1358 FEEPPSKG-TTVCGADVHEVGPGPSGLSEEQSRA---FPTPYLRVPVTLPERKGTSLSSE 1413
             +   S G  T   A V   G  PSG     S A    P     +P  LP       S+ 
Sbjct: 984  -QTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNL 1042

Query: 1414 SILSLEGSSSTAGG 1427
              L++  ++S+  G
Sbjct: 1043 PTLNVAKAASSGPG 1056



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 109/431 (25%), Positives = 161/431 (37%), Gaps = 62/431 (14%)

Query: 1021 TGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS 1080
            TG +AP     PA  APP           ++S P    L+  P+ +Q  + P P ++ P 
Sbjct: 612  TGEAAPVLTVQPAPQAPP-----------AVSTPLPLGLQ-QPQAQQPPQAPTPQAAAPP 659

Query: 1081 AKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTE-ALQVF-HHPVAQTPLH-EKP 1137
              ++       A+S    P     GQ  P   PT   T+ +LQ+F     +Q PL  E P
Sbjct: 660  QATTPQPSPGLASS----PEKIVLGQP-PSATPTAILTQDSLQMFLPQERSQQPLSAEGP 714

Query: 1138 YLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTV 1197
            +L  P S+     +    P Q P   +  A  + L      P    S   AP +P    +
Sbjct: 715  HLSVPASVI----VSAPPPAQDPAPATPVAKGAGLGP--QAPDSQASPAPAPQIPAAAPL 768

Query: 1198 LHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESH 1257
              PG    P L PH A  P    P  LP P+PT          P + Q   + P +   H
Sbjct: 769  KGPGPSSSPSL-PHQA--PLGDSPH-LPSPHPTRPPSRP----PSRPQSVSRPPSEPPLH 820

Query: 1258 L---PQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTM 1314
                PQ   +L  +      L              V PPAS+ APT+  P   P  P + 
Sbjct: 821  PCPPPQAPPTLPGIFVIQNQLG-------------VPPPASNPAPTAPGPPQPPLRPQSQ 867

Query: 1315 VSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKG---TTVCGA 1371
                 P+    ++P   S+  + ++    T S+  + T +  + + PPS+G   +     
Sbjct: 868  PP-EGPLPPAPHLPP--SSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPP 924

Query: 1372 DVHEVGPGPSGLSEEQSRAF-----PTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAG 1426
             +H V P P+       R F     P P L  P  L ER     S   + +  G +  A 
Sbjct: 925  TLHLV-PEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAP 983

Query: 1427 GSKRVLSPAGS 1437
             +   L P  S
Sbjct: 984  QTSTSLGPLTS 994



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 73/296 (24%), Positives = 102/296 (34%), Gaps = 46/296 (15%)

Query: 1867 EEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTA 1926
            +E SQ  LS           PH     S  +  P P   PA  T   +G+ +      + 
Sbjct: 702  QERSQQPLSAEG--------PHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQ 753

Query: 1927 SSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHS 1986
            +S + + Q     P  GP P  S      + L     SP  P        SRPP +R  S
Sbjct: 754  ASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLG---DSPHLPSPHPTRPPSRPP-SRPQS 809

Query: 1987 LTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELA 2046
            +++  S P    P   PQA  P+ PG+ V   +     P  +P                A
Sbjct: 810  VSRPPSEPP-LHPCPPPQA-PPTLPGIFVIQNQLGVPPPASNP----------------A 851

Query: 2047 PRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPR-SAPPGKWALAGPGSPSAGEHGPG 2105
            P           T PG P+     +  P +   PP    PP   + A   S       P 
Sbjct: 852  P-----------TAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPA 900

Query: 2106 -LGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSAL 2160
                D ++ FPP+  PHK  +  P     P   E  +P   P     + + PF AL
Sbjct: 901  PTPSDFQLQFPPSQGPHKSPTPPPTLHLVP---EPAAPPPPPPRTFQMVTTPFPAL 953



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 110/528 (20%), Positives = 169/528 (32%), Gaps = 126/528 (23%)

Query: 742  PSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKER-------RTTS 794
            P   +  LPL   +  A+     P+ +     Q  TP+P  G  S  E+         T 
Sbjct: 628  PPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATP 687

Query: 795  KEISVIQHTSSFEKSDSLEQPSGLEG-----------EDKPLAQFPSP-----------P 832
              I        F   +  +QP   EG              P AQ P+P           P
Sbjct: 688  TAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGP 747

Query: 833  PAPHGRSAHSLQPKLVRQPNIQVP----------EILVTEEPDRPDTEP-EPPPKEPEKT 881
             AP  +++ +  P++     ++ P          +  + + P  P   P  PP + P + 
Sbjct: 748  QAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRP 807

Query: 882  EEFQWPQRSQTLAQLPAEKLPPK-------KKRLRLAEMAQSSGESSFESSVPLSRSPSQ 934
            +    P     L   P  + PP        + +L +   A +   ++     P  R  SQ
Sbjct: 808  QSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQ 867

Query: 935  ESNVSL--------SGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAR 986
                 L        S +S + +   +   +  AP+PS      P        PS  PH  
Sbjct: 868  PPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFP--------PSQGPH-- 917

Query: 987  EMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLV 1046
                    +SP    + H+                    P P APP    PP  R   +V
Sbjct: 918  --------KSPTPPPTLHL-------------------VPEPAAPP----PPPPRTFQMV 946

Query: 1047 RQASLSRP-PESELE---VAPKGRQESEEPQPSSSKPSAKSSLSQISSAATS---HGGPP 1099
                 + P P++ LE     P G     +   + + P   +SL  ++S A S    G  P
Sbjct: 947  TTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAP 1006

Query: 1100 GGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLF-------SFQHLV 1152
             G           PT P          P+A T L   P LP     F       +     
Sbjct: 1007 SGT----------PTAPSHAPAPA---PMAATGL--PPLLPAENKAFASNLPTLNVAKAA 1051

Query: 1153 QHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHP 1200
               PG+ P     ++  S L  P ++ P   + F       Q +VLHP
Sbjct: 1052 SSGPGK-PSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHP 1098



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 125/527 (23%), Positives = 167/527 (31%), Gaps = 158/527 (29%)

Query: 1887 PHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAP 1946
            P +L A S P      P  PA+ T       V +   L  S+ +M +            P
Sbjct: 558  PVSLAAGSLPTQSQPAPAGPAATT-------VLQGVTLPPSAVAMLN-----------TP 599

Query: 1947 LGSVEKDTGSALSYK--PVSPRRPWSPSKEAGSRP-PLARKHSLTKNDSSPQRCSPAREP 2003
             G V+  T +A + +  PV   +P   +  A S P PL  +    +          A  P
Sbjct: 600  DGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPP 659

Query: 2004 QASAPSP-PGLHVDPGR-GMGALPCGSPRLQLSPLTL---CPLGRELAPRAHVLSKLEGT 2058
            QA+ P P PGL   P +  +G  P  +P   L+  +L    P  R   P +      EG 
Sbjct: 660  QATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLS-----AEG- 713

Query: 2059 TDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAP 2118
              P L   +     +P  A+ P  + P  K A  GP +P +                PAP
Sbjct: 714  --PHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQAS-------------PAP 758

Query: 2119 LPHKLLSRSPETCASPWKAESRSPSCSPGPAH--PLSSRPFSALHDFHGHILARTEENIF 2176
             P           A+P K     PS SP   H  PL   P                    
Sbjct: 759  APQI-------PAAAPLKGPG--PSSSPSLPHQAPLGDSP-------------------- 789

Query: 2177 SHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGARE 2236
             HLP  S H TR P    P    Q V +RP + P L P P                    
Sbjct: 790  -HLP--SPHPTRPPSR--PPSRPQSV-SRPPSEPPLHPCPPPQ----------------- 826

Query: 2237 AQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTG 2296
                             +P      F + ++L                G PP  +     
Sbjct: 827  -----------------APPTLPGIFVIQNQL----------------GVPPPASNPAPT 853

Query: 2297 APAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGC 2356
            AP  P P   P + P   P PP         +P L              PP   SS+V  
Sbjct: 854  APGPPQPPLRPQSQPPEGPLPP---------APHL--------------PPSSTSSAVAS 890

Query: 2357 LAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPP 2403
             +E S+R PA T +           P  S +  P  H   PE   PP
Sbjct: 891  SSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLH-LVPEPAAPP 936



 Score = 38.5 bits (88), Expect = 0.080
 Identities = 63/275 (22%), Positives = 95/275 (34%), Gaps = 50/275 (18%)

Query: 1049 ASLSRPPESELEVAPKGRQESEEPQPSSSKPSAK-SSLSQISSAATSHGGPPGGKGPGQD 1107
            AS   PP    ++  +       P  + ++ S+  SS S  SSAA+S      G  P ++
Sbjct: 1234 ASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRN 1293

Query: 1108 RPP-----------LGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEP 1156
            RPP           L   +     L    H  A  P+H+ P  PPP +L     + +  P
Sbjct: 1294 RPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPP--PPPATL----KVAEPPP 1347

Query: 1157 GQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIP 1216
               P    T  M+  +  P      PP+  +  PL   P        H P+L   P    
Sbjct: 1348 RPPPPPPPTGQMNGTVDHP------PPAAPERKPLGTAP--------HCPRL---PLRKT 1390

Query: 1217 FRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLS 1276
            +R+       P  T +  + G            LP  V+     +   LA +        
Sbjct: 1391 YRENVGGPGAPEGTPAGRARG-------GSPAPLPAKVDEATSGLIRELAAV-------- 1435

Query: 1277 PSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACP 1311
                Y   ++ PP  P AS++  T  P    P  P
Sbjct: 1436 EDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLP 1470



 Score = 37.4 bits (85), Expect = 0.18
 Identities = 90/381 (23%), Positives = 129/381 (33%), Gaps = 56/381 (14%)

Query: 2005 ASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCP-LGRE-LAPRAHVLSKLEGTTDPG 2062
            A A +  G  V  G G  + P G+P  Q  PL + P LG   L P  +V+  L  T  P 
Sbjct: 296  AVATTLNGNSVFGGAGAASAPTGTPSGQ--PLAVAPGLGSSPLVPAPNVI--LHRTPTPI 351

Query: 2063 LPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSP----------------SAGEHGPGL 2106
             P+  P     P   +  P+   P    L   G P                +AG+ G  +
Sbjct: 352  QPK--PAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNV 409

Query: 2107 GLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGH 2166
             L     FP   L   +  + P T       +       P   H L+    S++     H
Sbjct: 410  VLSG---FPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQG--SSIVIPAQH 464

Query: 2167 ILARTEENIFSHLPLHS--QHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGF 2224
            +L    + +    P     Q L+  P     +GG  +  A P     L+  P    ++  
Sbjct: 465  MLPGQNQFLLPGAPAVQLPQQLSALPAN---VGGQILAAAAPHTGGQLIANPI---LTNQ 518

Query: 2225 SGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGP 2284
            +  G    G   A   G  S    S+A +  V + + F +   L  G  P + +    GP
Sbjct: 519  NLAGPLSLGPVLAPHSGAHSAHILSAAPIQ-VGQPALFQMPVSLAAGSLPTQSQPAPAGP 577

Query: 2285 GR---------PPDW-----TPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSP- 2329
                       PP       TP G   PA P        P  T+   PQ   A  +  P 
Sbjct: 578  AATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPL 637

Query: 2330 RLESPRA---PTNPEPSATPP 2347
             L+ P+A   P  P P A  P
Sbjct: 638  GLQQPQAQQPPQAPTPQAAAP 658



 Score = 36.6 bits (83), Expect = 0.31
 Identities = 47/200 (23%), Positives = 72/200 (36%), Gaps = 18/200 (9%)

Query: 33  SSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEA---- 88
           ++ P P  G A+   SP + +L   P   P+++L + S +    Q++   + P+ A    
Sbjct: 661 ATTPQPSPGLAS---SPEKIVLGQPPSATPTAILTQDSLQMFLPQER--SQQPLSAEGPH 715

Query: 89  -SVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMR---PGPSGSFVAPGLHPQSQL 144
            SV  S +   P      +P  P     G   Q  D      P P     AP   P    
Sbjct: 716 LSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSS 775

Query: 145 LPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKP 204
            PS     P  D P +P    P P++   +P        R P +P  + C     P   P
Sbjct: 776 SPSLPHQAPLGDSPHLPS---PHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLP 832

Query: 205 SVLQKHIRSHTGERPYPCGP 224
            +    I++  G  P    P
Sbjct: 833 GIFV--IQNQLGVPPPASNP 850



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 49/199 (24%), Positives = 71/199 (35%), Gaps = 36/199 (18%)

Query: 8   KGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLA-----PQPFPG- 61
           KG      +P  + +   A Q  + ++ P  G G +++   P Q  L      P P P  
Sbjct: 741 KGAGLGPQAPDSQASPAPAPQ--IPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTR 798

Query: 62  --------PSSVLREGSQEKTGQQQKPPKRPPIEASVHISQ----LPQHPLTPAFMSPGK 109
                   P SV R  S+        PP+ PP    + + Q    +P     PA  +PG 
Sbjct: 799 PPSRPPSRPQSVSRPPSEPPL-HPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGP 857

Query: 110 PEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPS 169
           P+  L   +     P+ P       AP L P S      +S      LP       P PS
Sbjct: 858 PQPPLRPQSQPPEGPLPP-------APHLPPSSTSSAVASSSETSSRLP------APTPS 904

Query: 170 --QVSLKPTEEAHKKERKP 186
             Q+   P++  HK    P
Sbjct: 905 DFQLQFPPSQGPHKSPTPP 923


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 176/720 (24%), Positives = 237/720 (32%), Gaps = 151/720 (20%)

Query: 897  PAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGK 956
            P E+LP    + +   + ++ G  S E    L+ +     N SL      A   +     
Sbjct: 306  PMEELPAHSWKCKACRVCRACGAGSAE----LNPNSEWFENYSLCHRCHKAQGGQTIRSV 361

Query: 957  AEAPSP--SSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFD 1014
            AE  +P  S    P+P  T     P+  P A  +   A +  P   H   M         
Sbjct: 362  AEQHTPVCSRFSPPEPGDT-----PTDEPDALYV---ACQGQPKGGHVTSMQ-------- 405

Query: 1015 YGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQP 1074
                    P  P P+   A+       K  +  +  L  P   E+ + P   +    P P
Sbjct: 406  --------PKEPGPLQCEAKPLG----KAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPP 453

Query: 1075 SSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLH 1134
              S  S     S++S        PP         P   P  P  EAL +        PL 
Sbjct: 454  EESPTSPPPEASRLS--------PP---------PEELPASPLPEALHL------SRPLE 490

Query: 1135 EKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQ 1194
            E P  PPP      +  +   P  SP        S L  SP S P       ++PP P  
Sbjct: 491  ESPLSPPPE-----ESPLSPPPESSP-------FSPLEESPLSPPE------ESPPSPAL 532

Query: 1195 PTVLHPGQLHLPQLMPHPANIPFRQPPSFLPM-PYPTSSALS----SGFFLPLQSQFALQ 1249
             T L P     P L P     P   PP  LP  P P +S LS         P   +  + 
Sbjct: 533  ETPLSPPPEASP-LSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMS 591

Query: 1250 LPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPA 1309
             P +     P  + S        + LSP  E S   RL P  PP  S  P S PP   P 
Sbjct: 592  PPPEASRLFPPFEESPLSPPPEESPLSPPPEAS---RLSP--PPEDS--PMSPPPEESPM 644

Query: 1310 CPDTMVSLVVPVRVQTNM--PSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTT 1367
             P   VS + P+ V + +  P   S +          +   +S      +   PP    T
Sbjct: 645  SPPPEVSRLSPLPVVSRLSPPPEESPLSPP------PEESPTSPPPEASRLSPPPEDSPT 698

Query: 1368 VCGADVHEVGPGPS----GLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSS 1423
                +     P P      L  E+S   P P    P   P  +G  LS            
Sbjct: 699  SPPPEDSPASPPPEDSLMSLPLEESPLLPLP--EEPQLCPRSEGPHLSPRP--------- 747

Query: 1424 TAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEK 1483
                 +  LSP        E     + +E   S   E+     PC   +        PE+
Sbjct: 748  ----EEPHLSPRPE-----EPHLSPQAEEPHLSPQPEE-----PCLCAV--------PEE 785

Query: 1484 SHLGNQGQG-----RRELEMLSSLSSDP--SDTKEIPPL-PHPALSHGTAPGSE--ALKE 1533
             HL  Q +G     + E   LS  + +P  S   E P L P P  SH  +P SE   L  
Sbjct: 786  PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESH-LSPQSEEPCLSP 844

Query: 1534 YPQPSGKPHRRGLTPLSVKKEDSKEQP-------DLPSLAPPSSLPLSETSSRPAKSQEG 1586
             P+ S         PLS + E   E+P       +LP   PP    LS     PA S+ G
Sbjct: 845  RPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPG 904



 Score = 72.4 bits (176), Expect = 5e-12
 Identities = 160/608 (26%), Positives = 209/608 (34%), Gaps = 129/608 (21%)

Query: 1871 QDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCS 1930
            +  LS P  E+P   PP A R      L P P D+P S       +S    + L     S
Sbjct: 668  ESPLSPPPEESPTSPPPEASR------LSPPPEDSPTSPPPEDSPASPPPEDSLM----S 717

Query: 1931 MSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKN 1990
            +  +  P LP   P       +  G  LS +P  P    SP  E     P A +  L+  
Sbjct: 718  LPLEESPLLPL--PEEPQLCPRSEGPHLSPRPEEPHL--SPRPEEPHLSPQAEEPHLSPQ 773

Query: 1991 DSSPQRCSPAREPQAS--------APSPPGLHVDPGRGMGAL------PCGSPRLQLSPL 2036
               P  C+   EP  S        +P P  LH+ P      L      PC SP+ + S L
Sbjct: 774  PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHL 833

Query: 2037 TLCPLGRE--LAPR---AHVLSKLEGTTDPGLPRYSPTRRWSPGQAESP---PRSAPPGK 2088
            +  P   E  L+PR   +H+  +LE       P   P     PGQ  +P   P   PPG+
Sbjct: 834  S--PQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEE---PGQCPAPEELPLFPPPGE 888

Query: 2089 W---------ALAGPGSPSAGEHGPGLGLDPR-------VLFPPAPLPHKL---LSRSPE 2129
                      AL+ PG P        L L P         L PP PLP  L   ++ +  
Sbjct: 889  PSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAP 948

Query: 2130 TCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRA 2189
               SP   E   P  + G + P S      L      I    E N     P+    L  +
Sbjct: 949  PALSPL-GELEYPFGAKGDSDPESPLAAPILET---PISPPPEANCTDPEPVPPMILPPS 1004

Query: 2190 P-CPLIPIGGIQMV----------------------QARPGAHPTLLPGPTAAWVSGFSG 2226
            P  P+ P   I M                       Q  P A P  +P P +    G   
Sbjct: 1005 PGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSP--IGKVV 1062

Query: 2227 GGSDLTGARE------------AQERGRWSPTES-----SSASVSPVAKVSKFTLSSE-- 2267
            G SD     E            A E    SP  S     S  + SP   +  F+   E  
Sbjct: 1063 GVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDT 1122

Query: 2268 --LEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTH-SPCTPPDTLPRPPQGRRAA 2324
              L+G D P  +   G  PG          G+P    P   +P TP +  P   + ++ A
Sbjct: 1123 APLDGIDAPGSQPEPGQTPG---SLASELKGSPVLLDPEELAPVTPMEVYP---ECKQTA 1176

Query: 2325 QSWSP--RLESPRAPTNPEPSATPPLDRSSSVGCLA--EASARFPARTRNLSGEPRTRQD 2380
               SP    E PRAP  P P      D  + +  L+  +ASA FP        EP     
Sbjct: 1177 GQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFP------GSEPLL--G 1228

Query: 2381 SPKPSGSG 2388
            SP P G G
Sbjct: 1229 SPDPEGGG 1236



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 169/733 (23%), Positives = 245/733 (33%), Gaps = 140/733 (19%)

Query: 1755 VCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQETG 1814
            VC  CG    + +   +    ++     +C  CH   K +G  T    ++ H+  C    
Sbjct: 322  VCRACGAGSAELNPNSEWFENYS-----LCHRCH---KAQGGQTIRSVAEQHTPVCSRFS 373

Query: 1815 VLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLE----------------DSDSDSD 1858
              E  +      D L+   +G+     V   Q  +                  +   ++ 
Sbjct: 374  PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAP 433

Query: 1859 LDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGT-EATRGSS 1917
            L+E+        +  LS P  E+P   PP A R      L P P + PAS   EA   S 
Sbjct: 434  LNEEMPLLPPPEESPLSPPPEESPTSPPPEASR------LSPPPEELPASPLPEALHLSR 487

Query: 1918 VSEAERLTA----SSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSK 1973
              E   L+     S  S   +S P  P L  +PL   E+   S     P+SP    SP  
Sbjct: 488  PLEESPLSPPPEESPLSPPPESSPFSP-LEESPLSPPEESPPSPALETPLSPPPEASPLS 546

Query: 1974 EAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRL-- 2031
                  PL+           P+    +  P+ S  SPP     P     + P  + RL  
Sbjct: 547  PPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP-----PEESPMSPPPEASRLFP 601

Query: 2032 --QLSPLTLCPLGRELAPRAHVLSKLEGTTD----------------PGLPRYSP---TR 2070
              + SPL+  P    L+P     S+L    +                P + R SP     
Sbjct: 602  PFEESPLSPPPEESPLSPPPEA-SRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS 660

Query: 2071 RWSPGQAESP--------PRSAPPGKWALAGP-----------GSPSAGEHGPGLGLDPR 2111
            R SP   ESP        P S PP    L+ P            SP++      L   P 
Sbjct: 661  RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720

Query: 2112 VLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHP-LSSR---PFSALHDFHGHI 2167
               P  PLP +     P+ C       S  P  SP P  P LS R   P  +      H+
Sbjct: 721  EESPLLPLPEE-----PQLC-----PRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHL 770

Query: 2168 LARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGG 2227
              + EE     +P       +A  P +     ++  +     P L P P    +S     
Sbjct: 771  SPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLS----- 825

Query: 2228 GSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGR- 2286
                       E    SP +S    +SP  + S   LS ELE        E+    PG+ 
Sbjct: 826  --------PQPEESHLSP-QSEEPCLSPRPEESH--LSPELEKPPLSPRPEKPPEEPGQC 874

Query: 2287 ---------PPDWTPHGT---GAPAEPTPTHSPCTP-PDTLPRPPQGRRAAQSWSPRLES 2333
                     PP   P  +   G PA   P   P +P P+ LP  P G        P L  
Sbjct: 875  PAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG-------EPSLSP 927

Query: 2334 PRAPTNPEPSATPPLDRSSSVGCLAE-ASARFPARTRNLSGEPRTRQDSP--KPSGSGEP 2390
               P +P P    P+  +++   L+      +P   +    +P +   +P  +   S  P
Sbjct: 928  QLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKG-DSDPESPLAAPILETPISPPP 986

Query: 2391 RAHPHQPEDRVPP 2403
             A+   PE  VPP
Sbjct: 987  EANCTDPEP-VPP 998



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 209/918 (22%), Positives = 304/918 (33%), Gaps = 146/918 (15%)

Query: 674  PISAGTHTSP-----EAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDE-EEP 727
            P+S    +SP     E+  S  E  P S  +   L    E +PL    +E  L    EE 
Sbjct: 502  PLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL 561

Query: 728  PAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESG 787
            P     ++   SP P ++  + P E  +SP  P      L  P    P +P P    ES 
Sbjct: 562  PTSPPPEASRLSPPPEESPMSPPPE--ESPMSPPPEASRLFPPFEESPLSPPP---EESP 616

Query: 788  KERRTTSKEISVIQHTSSF----EKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSL 843
                  +  +S     S      E+S     P        P+    SPPP         L
Sbjct: 617  LSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPP-----EESPL 671

Query: 844  QPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLP- 902
             P     P    PE      P  P+  P  PP E         P    +L  LP E+ P 
Sbjct: 672  SPPPEESPTSPPPEASRLSPP--PEDSPTSPPPEDSPAS----PPPEDSLMSLPLEESPL 725

Query: 903  -PKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAP- 960
             P  +  +L   ++    S       LS  P +E ++S        S + ++      P 
Sbjct: 726  LPLPEEPQLCPRSEGPHLSPRPEEPHLSPRP-EEPHLSPQAEEPHLSPQPEEPCLCAVPE 784

Query: 961  ----SPSSD---MRPKPLGTHMLTVPSHHPHAREM-RRSASEQSPNVSHSAHMTETRSKS 1012
                SP ++   + P+P   H L+  +  PH   +         P  SH +  +E    S
Sbjct: 785  EPHLSPQAEGPHLSPQPEELH-LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLS 843

Query: 1013 FDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPK-GRQESEE 1071
                   L+      P++P     P E  +C    +  L  PP  E  ++P  G     E
Sbjct: 844  PRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLF-PPPGEPSLSPLLGEPALSE 902

Query: 1072 P-QPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTV-----PYTEALQVFH 1125
            P +P  S    +  LS     + S    P    P    PPL P +     P    L    
Sbjct: 903  PGEPPLSPLPEELPLSPSGEPSLS----PQLMPPDPLPPPLSPIITAAAPPALSPLGELE 958

Query: 1126 HPVAQ-----------TPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLL-- 1172
            +P               P+ E P  PPP +  +       +P   P      +  S +  
Sbjct: 959  YPFGAKGDSDPESPLAAPILETPISPPPEANCT-------DPEPVPPMILPPSPGSPVGP 1011

Query: 1173 SSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPP----------- 1221
            +SP  M PLPP         L P    P Q   P L   P ++P    P           
Sbjct: 1012 ASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPAL---PLSVPSPLSPIGKVVGVSDEA 1068

Query: 1222 -----SFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLS 1276
                     +  P   AL      PL S       GD+    P    S AP     +GL 
Sbjct: 1069 ELHEMETEKVSEPECPALEPSATSPLPSPM-----GDLSCPAP----SPAPALDDFSGLG 1119

Query: 1277 PSTEYSSDIRLP-----PVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYG 1331
              T     I  P     P   P S ++     P+ L   P+ +   V P+ V        
Sbjct: 1120 EDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLD--PEELAP-VTPMEV-------- 1168

Query: 1332 SAMYTTLSQILVTQSQGSSA-TVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSE-EQSR 1389
               Y    Q   T  QGS       P+    P+  T +    V+E+    S LS+ + S 
Sbjct: 1169 ---YPECKQ---TAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEI----SNLSQGDASA 1218

Query: 1390 AFP--TPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPA-----GSLELTM 1442
            +FP   P L  P       G SLS E  +S + S +   GS R+ + +      SL    
Sbjct: 1219 SFPGSEPLLGSP---DPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDA 1275

Query: 1443 ETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELE----- 1497
             T       E E  +        +      +S    +RP     G +G+GR  L+     
Sbjct: 1276 GTAISGGKAEGEKGRRRSSPARSRIKQGRSSSFPGRRRPRGGAHGGRGRGRARLKSTASS 1335

Query: 1498 ----MLSSLSSDPSDTKE 1511
                +++ + S PS  +E
Sbjct: 1336 IETLVVADIDSSPSKEEE 1353



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 221/1024 (21%), Positives = 329/1024 (32%), Gaps = 162/1024 (15%)

Query: 184  RKPQKPGKY-ICQYCSRP----CAKPSVLQKHIRSHTGERPYPCGPCGFSFK--TKSNLY 236
            RKP    K  +C+ C +     C KP + +    S   +    C  CG        ++ +
Sbjct: 280  RKPGNDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEW 339

Query: 237  KHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEET-------S 289
                S  HR         GG+      E        F  P  G++   E +         
Sbjct: 340  FENYSLCHRCH----KAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQ 395

Query: 290  ATSGHPAELSPRPKQPLLSSG--LYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSE 347
               GH   + P+   PL      L  +G          L++           P + P  E
Sbjct: 396  PKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEM---------PLLPPPEE 446

Query: 348  HPLSHKPEDTHTIKQKLALRLSERKKVID--------------EQAFLSPGSKGS----- 388
             PLS  PE++ T     A RLS   + +               E++ LSP  + S     
Sbjct: 447  SPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPP 506

Query: 389  TESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDK 448
             ES  FS  E  E  +SPP  +  S A             T +       PL P   E  
Sbjct: 507  PESSPFSPLE--ESPLSPPEESPPSPA-----------LETPLSPPPEASPLSPPFEESP 553

Query: 449  PSLVPLSVPRTQVIEHITKLITINEAVVD--TSEIDSVKPRRSSLSRRSSMESPKSSLYR 506
             S  P  +P +   E         E+ +     E     P  +S       ESP S    
Sbjct: 554  LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE 613

Query: 507  E-PLSSHSEKTK-------------PEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTI-- 550
            E PLS   E ++             PE+S +S     S   P+P++   S P     +  
Sbjct: 614  ESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP 673

Query: 551  -------STPHHPFRGSYSFDDHIT-----DSEALSHSSHVFTSHPRMLKRQPAIELPLG 598
                   S P    R S   +D  T     DS A         S P  L+  P + LP  
Sbjct: 674  PPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLP--LEESPLLPLPEE 731

Query: 599  GEYSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNY 658
             +      GP       +P     P+E  L+ + ++   +      C +C    +   + 
Sbjct: 732  PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPC-LCAVPEEPHLSP 790

Query: 659  EA---HKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKR 715
            +A   H      EL ++ P +   H SP  E+  +  +P        L    E   L  R
Sbjct: 791  QAEGPHLSPQPEELHLS-PQTEEPHLSPVPEEPCLSPQPEES----HLSPQSEEPCLSPR 845

Query: 716  RKEKSLGDE-EEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQ 774
             +E  L  E E+PP     +     PG   A   LPL     P EPS S P L  P    
Sbjct: 846  PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPL--FPPPGEPSLS-PLLGEP---- 898

Query: 775  PRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPA 834
                   + SE G+   +   E   +  +     S  L  P  L     P+    +PP  
Sbjct: 899  -------ALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL 951

Query: 835  --------PHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQW 886
                    P G    S     +  P ++ P I    E +  D EP PP   P        
Sbjct: 952  SPLGELEYPFGAKGDSDPESPLAAPILETP-ISPPPEANCTDPEPVPPMILPPSPGSPVG 1010

Query: 887  PQRSQTLAQLPAEKLPPKKKRLRLAEMAQSS-GESSFESSVPLSRSPSQESNVSLSGSSR 945
            P     +  LP +  P  +  L       S     +   SVP   SP  +  V +S  + 
Sbjct: 1011 PASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKV-VGVSDEAE 1069

Query: 946  SASFERDDHGKAEAPS---PSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHS 1002
                E +   + E P+    ++   P P+G      PS  P   +      + +P     
Sbjct: 1070 LHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAP----- 1124

Query: 1003 AHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVA 1062
                           +   G S P P   P  +A   +    L+    L+  P + +EV 
Sbjct: 1125 ------------LDGIDAPG-SQPEPGQTPGSLASELKGSPVLLDPEELA--PVTPMEVY 1169

Query: 1063 PKGRQ---------ESEEPQ-PSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLG 1112
            P+ +Q         E EEP+ P +  P        ++  +    G      PG + P LG
Sbjct: 1170 PECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSE-PLLG 1228

Query: 1113 PTVP 1116
               P
Sbjct: 1229 SPDP 1232



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 124/544 (22%), Positives = 189/544 (34%), Gaps = 97/544 (17%)

Query: 812  LEQPSG-LEGEDKPLAQFPSPPPA---------PHGRS-AHSLQPKLVRQPNIQVPEILV 860
            L+ P+G + G D P   F   PP          P G + A+ L+P+    P    P    
Sbjct: 2143 LKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSP 2202

Query: 861  TEEPDRPDTEPEPPPKEPEKTEEFQW--PQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSG 918
            T  P +P            +  EF    P   +     P   L P+   L    + +S G
Sbjct: 2203 TGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG 2262

Query: 919  ESSFESSVPL-SRSPSQESNVSLS------GSSRSASFERDDHGKAEAPSPSSDMRPKPL 971
                ++S PL S  P  ES  +L       G+S S S+   + G  ++PS  + +    L
Sbjct: 2263 VGGGKASEPLLSPPPFGESRKALEVKKEELGAS-SPSYGPPNLGFVDSPSSGTHLGGLEL 2321

Query: 972  GTHMLTVPSHHPHAREMRRSAS------EQSPNVSHSAHMTETRSKSFDYGSLSLTGPSA 1025
             T  +      P A ++   +       ++ P     A    +    F  GS   T P A
Sbjct: 2322 KTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSY--TDPYA 2379

Query: 1026 PAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEE---PQPSSSKPSAK 1082
              P+ P  +  PPE   C  +   SL   P S +  +P+ +  S+    P+P S++    
Sbjct: 2380 QPPLTPRPQPPPPE--SCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCP 2437

Query: 1083 SSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPP 1142
            S ++    +   +  PP      Q R P                     PLH+ P   PP
Sbjct: 2438 SPVTPRFQSPDPYSRPPSRP---QSRDPF-------------------APLHKPPRPQPP 2475

Query: 1143 VSLFSFQHLVQHE-----------------------PGQSPEFFSTQAMSSLLSSPYSMP 1179
               F    L                            GQ P F  +    + + +P  M 
Sbjct: 2476 EVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMR 2535

Query: 1180 PLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFF 1239
               P     P   L+P V  PG   LP   PH  N  F   P+ L  P  T+  +++G F
Sbjct: 2536 FTFPQAVGEP--SLKPPVPQPG---LPP--PHGINSHFGPGPT-LGKPQSTNYTVATGNF 2587

Query: 1240 LPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAP 1299
             P  S          ES+       L+PL   S    P+ + S    LP ++  AS  + 
Sbjct: 2588 HPSGSPLGPSSGSTGESY------GLSPLRPPSVLPPPAPDGS----LPYLSHGASQRSG 2637

Query: 1300 TSAP 1303
             ++P
Sbjct: 2638 ITSP 2641



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 266/1251 (21%), Positives = 380/1251 (30%), Gaps = 260/1251 (20%)

Query: 1022 GPSAPAPVAPPARVAPP--ERRKCFLVRQASLSR------PPESELEVAPKGRQES---E 1070
            G  A  P+  P    PP  E RK   V++  L        PP      +P         E
Sbjct: 2265 GGKASEPLLSP----PPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLE 2320

Query: 1071 EPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQ 1130
               P   K       SQ+   +   G  P    P Q   P  P+ P       +  P AQ
Sbjct: 2321 LKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQ 2380

Query: 1131 TPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAP- 1189
             PL  +P  PPP S  +        P   P    ++  +S  S   S  PL P    A  
Sbjct: 2381 PPLTPRPQPPPPESCCAL------PPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEA 2434

Query: 1190 --PLPLQPTVLHPGQLHLPQLMPHPAN--IPFRQPPSFLPMPYPTSSALSSGFFLPLQ-- 1243
              P P+ P    P     P   P   +   P  +P    P P P   A  +G        
Sbjct: 2435 FCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKP----PRPQPPEVAFKAGSLAHTSLG 2490

Query: 1244 -SQFALQLPGDVESHL-PQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTS 1301
               F   LP      L  ++ +   P    S G        S +R      P +   P+ 
Sbjct: 2491 AGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRF---TFPQAVGEPSL 2547

Query: 1302 APPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEP 1361
             PP+  P  P                P +G   +      L  + Q ++ TVA   F   
Sbjct: 2548 KPPVPQPGLP----------------PPHGINSHFGPGPTL-GKPQSTNYTVATGNFHPS 2590

Query: 1362 -----PSKGTTVCGADVHEVGP-GPSGLSEEQSRAFPTPYL------RVPVTLPERK--- 1406
                 PS G+T    + + + P  P  +    +     PYL      R  +T P  K   
Sbjct: 2591 GSPLGPSSGST---GESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKRED 2647

Query: 1407 -GTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQK------RVKEEEASKAD 1459
             GT + S        ++   G     +S     EL  + Q+Q+      R + +  +   
Sbjct: 2648 PGTGMGSSL-----ATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQ 2702

Query: 1460 EKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPP--LPH 1517
            EK         V      G  P         +G+       + + D S    +PP  L  
Sbjct: 2703 EKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPF----AGTQDKSSLVGLPPSKLSG 2758

Query: 1518 PALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSK----EQPDLPSLAPPSSLPL 1573
            P L  G+ P  + L   P P+        TP S+     +     Q        P SLPL
Sbjct: 2759 PILGPGSFPSDDRLSRPPPPA--------TPSSMDVNSRQLVGGSQAFYQRAPYPGSLPL 2810

Query: 1574 SETSSRPAKSQEGTDSKKV-----LQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYA 1628
             +   +  + Q+ T +  +      +FPS                P          S  A
Sbjct: 2811 QQQQQQLWQQQQATAATSMRFAMSARFPS---------------TPGPELGRQALGSPLA 2855

Query: 1629 GWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEV 1688
            G    L  P  P          +  +  V K      T P P  G       ++PR   V
Sbjct: 2856 GISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGT-PFPGQG-----PPQRPRFYPV 2909

Query: 1689 -HLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGE-------------PARIKIFE 1734
               P  ++PEG + LA      ++   P    PA +                P  +++  
Sbjct: 2910 SEDPHRLAPEGLRGLAVSGLPPQKPSAP----PAPELNNSLHPTPHTKGPTLPTGLELVN 2965

Query: 1735 GGYKSNEEYVYVRGRGRGKYVCEECG-IRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKT 1793
                S E        GR   +  E G + C+ P +                   H A + 
Sbjct: 2966 RPPSSTE-------LGRPNPLALEAGKLPCEDPELDDDF-------------DAHKALED 3005

Query: 1794 KGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDS 1853
               L         +K   E G LE LE  +   DDL    E    +    E    D +D 
Sbjct: 3006 DEELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDI 3065

Query: 1854 DSDSDLDEDEDEDEEESQDELSR---PSSEAPPPGPPHALRADS---------------- 1894
             ++  L   E  +E+  ++ L R   P    P   PP A  A                  
Sbjct: 3066 FNE-HLRLVESANEKAEREALLRGVEPGPLGPEERPPPAADASEPRLASVLPEVKPKVEE 3124

Query: 1895 -----SP----ILGPQPPDAPAS--------------GTEATR-GSSVSEAERLTASSCS 1930
                 SP    I  P+   APA+              G+  TR G+    +   TA   S
Sbjct: 3125 GGRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKAS 3184

Query: 1931 MSSQSMPGLPWLGPAPL----GSVEKDTGSALSYKPVSPRRPWSPSKE--------AGSR 1978
              +   P    L P+PL    GS   +     S     P  P +   E          S 
Sbjct: 3185 FGATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASE 3244

Query: 1979 PPLA-------RKHSLTKNDSSPQRCSPAREPQ--------ASAPSPPGLHVDPGRGMGA 2023
             PL         K  L K      +  PA++ Q         SAP P      P  G   
Sbjct: 3245 LPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSP 3304

Query: 2024 LPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRS 2083
               GS + QLS      LG            L G   PGLP+  P     P  A +  + 
Sbjct: 3305 SLAGSQQ-QLS------LG------------LAGARQPGLPQ--PLMPTQP-PAHALQQR 3342

Query: 2084 APPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASP 2134
              P    ++  G   +G+HG   GL P+    P      + +  P  C  P
Sbjct: 3343 LAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKP 3393



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 46/161 (28%), Positives = 62/161 (38%), Gaps = 28/161 (17%)

Query: 38  PGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEA-------SV 90
           P    + T   P    L+P P   P+S L E        ++ P   PP E+       S 
Sbjct: 451 PPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESS 510

Query: 91  HISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHAS 150
             S L + PL+P   SP  P          L  P+ P P  S ++P    +S L P    
Sbjct: 511 PFSPLEESPLSPPEESPPSP---------ALETPLSPPPEASPLSPPFE-ESPLSP---- 556

Query: 151 IIPPEDLPGVPKVFVPRPSQVSLKPTEE--AHKKERKPQKP 189
             PPE+LP  P    P  S++S  P E   +   E  P  P
Sbjct: 557 --PPEELPTSPP---PEASRLSPPPEESPMSPPPEESPMSP 592



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 69/313 (22%), Positives = 101/313 (32%), Gaps = 58/313 (18%)

Query: 46  QESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFM 105
           +ESP        P   P    R     +      PP+  P+     +S+L   P+     
Sbjct: 604 EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLS 663

Query: 106 SPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLH--PQSQLLPSHASIIPPED----LPG 159
            P +   L   S      P  P P  S ++P     P S       +  PPED    LP 
Sbjct: 664 PPPEESPL---SPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720

Query: 160 VPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERP 219
                +P P +  L P  E      +P++P  ++      P   P   + H+       P
Sbjct: 721 EESPLLPLPEEPQLCPRSEGPHLSPRPEEP--HLSPRPEEPHLSPQAEEPHL------SP 772

Query: 220 YPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEG 279
            P  PC  +   + +L    +              G  + P   E+   P  + EEP   
Sbjct: 773 QPEEPCLCAVPEEPHLSPQAE--------------GPHLSPQPEELHLSP--QTEEP--- 813

Query: 280 ESTDSEEETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERC---SLSQSSTAQSLE 336
                             LSP P++P LS     S     S E C      +S  +  LE
Sbjct: 814 -----------------HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELE 856

Query: 337 DPPPFVEPSSEHP 349
            PP  + P  E P
Sbjct: 857 KPP--LSPRPEKP 867



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 66/262 (25%), Positives = 86/262 (32%), Gaps = 70/262 (26%)

Query: 1867 EEESQDELSRPSSEAPPPGPPHALRADSSP----ILGPQP-----PDAPASGTEATRGSS 1917
            + + +  L+ P  E P   PP A   D  P    IL P P     P +P          S
Sbjct: 966  DSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCS 1025

Query: 1918 VSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGS 1977
                  L   +   S  S P LP   P+PL  + K  G       VS             
Sbjct: 1026 PLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVG-------VSDE----------- 1067

Query: 1978 RPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLT 2037
                A  H +     S   C PA EP A++P P          MG L C +P    +   
Sbjct: 1068 ----AELHEMETEKVSEPEC-PALEPSATSPLP--------SPMGDLSCPAPSPAPALDD 1114

Query: 2038 LCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSP 2097
               LG + AP       L+G   PG        +  PGQ                 PGS 
Sbjct: 1115 FSGLGEDTAP-------LDGIDAPG-------SQPEPGQT----------------PGSL 1144

Query: 2098 SAGEHGPGLGLDPRVLFPPAPL 2119
            ++   G  + LDP  L P  P+
Sbjct: 1145 ASELKGSPVLLDPEELAPVTPM 1166



 Score = 38.5 bits (88), Expect = 0.080
 Identities = 110/443 (24%), Positives = 150/443 (33%), Gaps = 96/443 (21%)

Query: 1976 GSRPPLARKHSLTKNDSSPQRCSPARE-----PQASAPSPPGLHVDPGRGMGALPCGSPR 2030
            GS PP A       + ++P   S + +     P  S P P      PG     LP   P+
Sbjct: 2114 GSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDS----PGELFLKLP---PQ 2166

Query: 2031 LQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQ-----AESPPRSAP 2085
            +     +  P G  LAP A+ L     T  P  P Y P+   +P Q     A S P +  
Sbjct: 2167 VPAQVPSQDPFG--LAP-AYPLEPRFPTAPPTYPPY-PSPTGAPAQPPMLGASSRPGAGQ 2222

Query: 2086 PGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCS 2145
            PG++    PG+P    H P    DP  L P  P        S +  A P      SP   
Sbjct: 2223 PGEFHTTPPGTP---RHQPSTP-DP-FLKPRCP--------SLDNLAVP-----ESPGVG 2264

Query: 2146 PGPAHP--LSSRPFSALHDFHGHILARTEENIFSHLPLHSQH---LTRAPCPLIPIGGIQ 2200
             G A    LS  PF          L   +E + +  P +         +P     +GG++
Sbjct: 2265 GGKASEPLLSPPPFGESRK----ALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLE 2320

Query: 2201 MVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVS 2260
            +        P     P A+ V   S G     G R  +      P  + + + SP +   
Sbjct: 2321 LKTPDVFKAPLT---PRASQVEPQSPG----LGLRPQE------PPPAQALAPSPPSHPD 2367

Query: 2261 KFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQG 2320
             F   S  +              P   P  TP     P  P P      PP +LP  P  
Sbjct: 2368 IFRPGSYTD--------------PYAQPPLTPR----PQPPPPESCCALPPRSLPSDPFS 2409

Query: 2321 RRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQD 2380
            R  A   S    S ++P  P P +             AEA    P   R  S +P +R  
Sbjct: 2410 RVPASPQSQ--SSSQSPLTPRPLS-------------AEAFCPSPVTPRFQSPDPYSR-- 2452

Query: 2381 SPKPSGSGEPRAHPHQPEDRVPP 2403
             P    S +P A  H+P    PP
Sbjct: 2453 PPSRPQSRDPFAPLHKPPRPQPP 2475



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 57/271 (21%), Positives = 99/271 (36%), Gaps = 35/271 (12%)

Query: 840  AHSLQPKLVRQP-----NIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLA 894
            +HS QPKL  QP      +Q  + L  ++  +   + +   ++  + ++ Q  Q+ Q L 
Sbjct: 3882 SHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQ 3941

Query: 895  QLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDH 954
            Q   ++L  ++++L   +  Q   +  F+          Q+  + L   SR+    +   
Sbjct: 3942 QQQQQQLQQQQQQL---QQQQQQQQQQFQQQ-------QQQQQMGLLNQSRTLLSPQQQQ 3991

Query: 955  GKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFD 1014
             +  A  P   M  KPL  H  +  +  P      +  +   P VS  A    T   S  
Sbjct: 3992 QQQVALGPG--MPAKPL-QHFSSPGALGPTLLLTGKEQNTVDPAVSSEA----TEGPSTH 4044

Query: 1015 YGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQP 1074
             G     G +  +    P  V P       L+      +P  S L++ P  R   ++ Q 
Sbjct: 4045 QGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQ- 4103

Query: 1075 SSSKPSAKSSLSQISSAATSHGGPPGGKGPG 1105
                        Q+S   T+ GG  G  G G
Sbjct: 4104 ------------QVSLLHTAGGGSHGQLGSG 4122



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 69/273 (25%), Positives = 97/273 (35%), Gaps = 49/273 (17%)

Query: 1856 DSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPP------------ 1903
            +++L E E E   E +     PS+ +P P P   L   S P   P P             
Sbjct: 1067 EAELHEMETEKVSEPECPALEPSATSPLPSPMGDL---SCPAPSPAPALDDFSGLGEDTA 1123

Query: 1904 -----DAPASGTE--ATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGS 1956
                 DAP S  E   T GS  SE   L  S   +  + +  +  +   P        GS
Sbjct: 1124 PLDGIDAPGSQPEPGQTPGSLASE---LKGSPVLLDPEELAPVTPMEVYPECKQTAGQGS 1180

Query: 1957 ALSYKPVSPRRPWSPSKEAGSRPPLARKHS-LTKNDSSPQRCSPAREPQASAPSPPG--- 2012
                +   PR P +P+     +  +  + S L++ D+S     P  EP   +P P G   
Sbjct: 1181 PCE-EQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASAS--FPGSEPLLGSPDPEGGGS 1237

Query: 2013 --------LHVDPGRGMGALP-CGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGL 2063
                      V P R  G+L  C     +     LC  G  ++       K EG  + G 
Sbjct: 1238 LSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISG-----GKAEG--EKGR 1290

Query: 2064 PRYSPTR-RWSPGQAESPPRSAPPGKWALAGPG 2095
             R SP R R   G++ S P    P   A  G G
Sbjct: 1291 RRSSPARSRIKQGRSSSFPGRRRPRGGAHGGRG 1323



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 28/95 (29%), Positives = 35/95 (36%), Gaps = 15/95 (15%)

Query: 1021 TGP-----SAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPS 1075
            TGP     + P P  PP   APP       V       PP S            +EP+  
Sbjct: 4271 TGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSS----------PQEPKRP 4320

Query: 1076 SSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPP 1110
            S  PS  S L   +    +H G P  +GP  + PP
Sbjct: 4321 SQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPP 4355



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 21/67 (31%), Positives = 26/67 (38%), Gaps = 1/67 (1%)

Query: 2287 PPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATP 2346
            PP   P    +P  P+P   P  P   LP  P       S  P   SP +   P+P A P
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPES-ARPKPRARP 4967

Query: 2347 PLDRSSS 2353
            P +   S
Sbjct: 4968 PEEGEDS 4974



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 29/112 (25%), Positives = 47/112 (41%), Gaps = 8/112 (7%)

Query: 795  KEISVIQHTSSFEKSDSLEQP-SGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNI 853
            ++   ++ T  +++  +   P  GL G    L  FP P   P        +P+    P +
Sbjct: 4232 QQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQ--GPPRL 4289

Query: 854  QVPEILVTEEPDRPDTEPEPPPKEPEKTEE-FQWPQRSQTLAQLPAE-KLPP 903
              P   ++  P      P PPP  P++ +   Q P  S   +QLP E +LPP
Sbjct: 4290 PAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPS---SQLPTEAQLPP 4338



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 14/96 (14%)

Query: 1500 SSLSSDPSDTKEIPPLPHPALS----HGTAPGSEALKEYPQ--PSGKPHRRGLTPLSVKK 1553
            ++LS+ P+    +PP P P++     +G  P SE L E+P+   S +   R L       
Sbjct: 4614 NNLSNPPTPPSSLPPTPPPSVQQKMVNGVTP-SEELGEHPKDAASARDSERAL------- 4665

Query: 1554 EDSKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDS 1589
             D+ E   L  LA   + P ++T     +S E +DS
Sbjct: 4666 RDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDS 4701


>gi|154146199 sal-like 3 [Homo sapiens]
          Length = 1300

 Score = 72.8 bits (177), Expect = 4e-12
 Identities = 108/423 (25%), Positives = 156/423 (36%), Gaps = 78/423 (18%)

Query: 3   PEQSVKGTKKAEGSPRKRLTKGEAIQTSVSS-SVPYPGSGTAATQE-SPAQELLAPQPFP 60
           P  S      A G    +L    A+  S  + +    GSG AA      AQ L  P+   
Sbjct: 240 PSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGA 299

Query: 61  GPSSVLREGSQEKTGQQQKPPKRP---PIEASVHISQLPQHPLTPAFMSPGKPEHLLEGS 117
                  E S          P  P   P   S   SQ PQ   TP  ++PG     L G+
Sbjct: 300 STPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQ-PQSASTPPALAPGS----LLGA 354

Query: 118 TWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTE 177
              L  P+ P  S S    G+   + L+   A+    + L  + K    +P  VS+    
Sbjct: 355 APGLPSPLLPQTSAS----GVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSV---- 406

Query: 178 EAHKKERKPQKPG-KYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLY 236
              + +   + P  K+ C++C++     S LQ H+RSHTGERP+ C  CG  F TK NL 
Sbjct: 407 --FEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLK 464

Query: 237 KHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPA 296
            H + H              E YPH ++M   P  E+            +     SG P 
Sbjct: 465 VHFQRHK-------------EKYPH-IQMNPYPVPEY-----------LDNVPTCSGIPY 499

Query: 297 ELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPP------FVEPSSEHPL 350
            +S  P++P+           +    +  L    T+  L+ PP       + +  S  P 
Sbjct: 500 GMSLPPEKPVT----------TWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPA 549

Query: 351 SHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQV-SPPNT 409
           S  P+                     E A LSPG     ESG  + +ES +  +  PP T
Sbjct: 550 SRSPQ--------------RPSPASSECASLSPG-LNHVESGVSATAESPQSLLGGPPLT 594

Query: 410 NAK 412
            A+
Sbjct: 595 KAE 597



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 171/785 (21%), Positives = 275/785 (35%), Gaps = 124/785 (15%)

Query: 1288 PPVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQ 1347
            P ++P A+ SAP  AP   LP      +S   P            A +     +  ++ +
Sbjct: 240  PSLSPAAAPSAPGPAPS-QLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPL--SRPE 296

Query: 1348 GSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKG 1407
              ++T   P     P+  +           P P   +  Q ++  TP    P +L    G
Sbjct: 297  SGASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSL---LG 353

Query: 1408 TSLSSESILSLEGSSSTAGGSKRVLS---PAGSLELTMETQQQKRVKEEEASKADEKLEL 1464
             +    S L  + S+S       ++S    A +L+      + ++ K    S  + K   
Sbjct: 354  AAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASA 413

Query: 1465 VKP--------CSVVLTS---------TEDGKRPEKSHL-GNQGQGRRELEMLSSLSSDP 1506
              P        C+ V  S         +  G+RP K ++ GN+   +  L++      + 
Sbjct: 414  EDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK 473

Query: 1507 SDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLA 1566
                ++ P P P          E L   P  SG P+   L P          +P LP++ 
Sbjct: 474  YPHIQMNPYPVP----------EYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVP 523

Query: 1567 PPSSLPLSET---SSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCY-LNYIKPNHIQHADR 1622
                L L  T   +   A S   T + +  Q PS  ++   S    LN+++      A+ 
Sbjct: 524  TSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAES 583

Query: 1623 RSSVYAGWCISLYNP-NLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSR 1681
              S+  G  ++   P +LP  + +A  + + ++   +  +   A       G    S   
Sbjct: 584  PQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQF 643

Query: 1682 KPRMTEVHL-PSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSN 1740
            K +     L  S+ + E  K    VE  +++  +P +                       
Sbjct: 644  KAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQ----------------------- 680

Query: 1741 EEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800
                           C  C       S LK H RTHT  RP+ CK C  AF TKGNL  H
Sbjct: 681  ---------------CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTH 725

Query: 1801 M---KSK-----AHS-----KKCQETGVLEE-LEAEEGTSDDLFQDSEGREGSEAVEEHQ 1846
                ++K      HS     KK     VL++ +    G         EG +  +A++   
Sbjct: 726  FGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQ--DAMDSEL 783

Query: 1847 FSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAP 1906
              D +++++ S  D+D DE+  E   EL      A  P  P    A S P   P PP   
Sbjct: 784  AYDDKNAETLSSYDDDMDENSMEDDAEL---KDAATDPAKPLLSYAGSCP---PSPPSVI 837

Query: 1907 ASGTEATRGSSVSEAE-RLTASSCSMSSQSMPGLPWL--GPAPLGSVEKDTGSAL----S 1959
                     SS++  E ++      MS Q + GL  +  G      +  D+ SA+    S
Sbjct: 838  ---------SSIAALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLES 888

Query: 1960 YKPVSPRRPWSPSKEAGSRPPLARKHSLTKN-----DSSPQRCSPAREPQASAPSPPGLH 2014
                SP    S S +A S  P   +   +K+        PQ      E   S  + PG  
Sbjct: 889  RSAGSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSG 948

Query: 2015 VDPGR 2019
              PGR
Sbjct: 949  GAPGR 953



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 49/159 (30%), Positives = 67/159 (42%), Gaps = 20/159 (12%)

Query: 92   ISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDP-MRPGPSGSF------VAPGLHPQSQL 144
            +  L QH LT          H L+    QL DP    GPS S        AP +      
Sbjct: 1017 MGNLKQHLLT----------HRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKME-- 1064

Query: 145  LPSHASIIPPEDLPGVPK-VFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAK 203
            +  H   +   + P +P  V VP   Q  + P           + P ++ CQ C +  + 
Sbjct: 1065 VNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSS 1124

Query: 204  PSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242
             S LQ H R+HTGE+P+ C  CG +F TK NL  H  +H
Sbjct: 1125 ASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 167/708 (23%), Positives = 240/708 (33%), Gaps = 129/708 (18%)

Query: 753  STKSPAEPS--KSVPSLEGPTGFQPRTPKPGSGSE---SGKERRTTSKEISVIQHTSS-- 805
            S +  A+P   KS   L  P G  P    PG G+E   SG E R+  +E SV +   +  
Sbjct: 2    SRRKQAKPQHLKSDEELLPPDG-APEHAAPGEGAEDADSGPESRSGGEETSVCEKCCAEF 60

Query: 806  FEKSDSLEQ--------PSGLEGEDKPLA---QFPSPPPAPH-GRSAHSLQPKLVRQPNI 853
            F+ +D LE         P  +  ED P      FP P PA      A S   +       
Sbjct: 61   FKWADFLEHQRSCTKLPPVLIVHEDAPAPPPEDFPEPSPASSPSERAESEAAEEAGAEGA 120

Query: 854  QVPEILVTEEPDRPDTEP-------EPPPKEPEK-TEEFQWPQRSQTLAQLPAEKLPPKK 905
            +     V +E +  D EP        PPP  P   T  +  P  + TL  L    L  K 
Sbjct: 121  EGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTPAYGAPSTNVTLEAL----LSTKV 176

Query: 906  KRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFE-----RDDHGKAEAP 960
               + ++ A+++G S     V  +  P     +      +    +     R      + P
Sbjct: 177  AVAQFSQGARAAGGSGAGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRP 236

Query: 961  SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSL 1020
             P   + P    +     PS  P    +  SA   +  ++ S                  
Sbjct: 237  PPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGS------------------ 278

Query: 1021 TGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPS 1080
             GP+APA       ++ PE         ++   P E     AP        P P+ +  S
Sbjct: 279  -GPAAPAAFEGAQPLSRPESGA------STPGGPAEPSAPAAPSAAPAPAAPAPAPAPQS 331

Query: 1081 AKSSLSQISSAATSHGGPPG---GKGPGQDRPPLGPTVPYTEALQV-FHHPV-------- 1128
            A S  SQ  SA+T     PG   G  PG       P +P T A  V F +P+        
Sbjct: 332  AAS--SQPQSASTPPALAPGSLLGAAPGLP----SPLLPQTSASGVIFPNPLVSIAATAN 385

Query: 1129 AQTPL-----HEKPYLPPPVSLFS---------FQHLVQHEPGQSPEFFSTQAMSSLLSS 1174
            A  PL     H K   PP VS+F          F+H  +     +  F S  A+   L S
Sbjct: 386  ALDPLSALMKHRKG-KPPNVSVFEPKASAEDPFFKHKCRF---CAKVFGSDSALQIHLRS 441

Query: 1175 PYSMPPLPPSL----FQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPT 1230
                 P   ++    F            H  +    Q+ P+P        P +L    PT
Sbjct: 442  HTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPV-------PEYLD-NVPT 493

Query: 1231 SSALSSGFFLPLQSQFALQLPGDVESHLPQIKTS----LAPLATGSAGLSPSTEYSSDIR 1286
             S +  G  LP +      L  D +  LP + TS    L P   G+ G + S   +   R
Sbjct: 494  CSGIPYGMSLPPEKPVTTWL--DSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASR 551

Query: 1287 LPPVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILV--T 1344
             P    PASS   + +P L         V   V    ++     G    T    + +  T
Sbjct: 552  SPQRPSPASSECASLSPGL-------NHVESGVSATAESPQSLLGGPPLTKAEPVSLPCT 604

Query: 1345 QSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFP 1392
             ++   A V       P    T+V GA      PG   +SE+    FP
Sbjct: 605  NARAGDAPVGAQASAAP----TSVDGAPTSLGSPGLPAVSEQFKAQFP 648



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 78/368 (21%), Positives = 123/368 (33%), Gaps = 83/368 (22%)

Query: 79  KPPKRPPIEASVHISQLP--QHPLTPAFMSPGKPEHLLEGSTWQLVDPMR-PGPSGSFVA 135
           + P+RP   +S   S  P   H  +    +   P+ LL G      +P+  P  +     
Sbjct: 551 RSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGD 610

Query: 136 PGLHPQSQLLPSHASIIPPE-DLPGVP------KVFVPRPSQVSLKPTEEAHKKERKPQK 188
             +  Q+   P+     P     PG+P      K   P    +    T E  K ++  + 
Sbjct: 611 APVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVEN 670

Query: 189 PGKYI-----CQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHA 243
             K +     C  C R  +  S L+ H R+HTGERP+ C  CG +F TK NL  H   H 
Sbjct: 671 IDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHR 730

Query: 244 HR---------------------IKAGLASGMGGEM--------YPHGLEMERIPGEEFE 274
            +                     ++  +   MGG++        +   ++ E    ++  
Sbjct: 731 AKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMDSELAYDDKNA 790

Query: 275 EPTEGESTDSEEETSATSGHPAELSPRPKQPLLS-------------------------- 308
           E       D +E +        + +  P +PLLS                          
Sbjct: 791 ETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSIAALENQMKMI 850

Query: 309 ---------SGLYSSGSHSSSHERCSLSQSSTAQSLED----PPPFVEPSSEHPLSHKPE 355
                    +GL S  + S   +R S   SS    LE      P   E SS   LS  P 
Sbjct: 851 DSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSSQALSPAPS 910

Query: 356 DTHTIKQK 363
           +  + + K
Sbjct: 911 NGESFRSK 918



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 48/149 (32%), Positives = 65/149 (43%), Gaps = 24/149 (16%)

Query: 1657 VSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPE 1716
            +S+ + + A +P P  G    S S          P L +PE  ++   +  + ER   P 
Sbjct: 896  LSESSSSQALSPAPSNGESFRSKS----------PGLGAPEEPQE---IPLKTERPDSPA 942

Query: 1717 EDAPASQRGEPARIKIFEGGYKSNEEYVYVRGRGRGKYVCEECGIRCKKP----SMLKKH 1772
              AP S  G P R  I E    S    +    R RGK     CG+ C KP    S L+ H
Sbjct: 943  A-APGSG-GAPGRAGIKEEAPFS----LLFLSRERGKCPSTVCGV-CGKPFACKSALEIH 995

Query: 1773 IRTHTDVRPYVCKHCHFAFKTKGNLTKHM 1801
             R+HT  RP+VC  C     T GNL +H+
Sbjct: 996  YRSHTKERPFVCALCRRGCSTMGNLKQHL 1024



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 22/46 (47%), Positives = 26/46 (56%)

Query: 1756 CEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM 1801
            C+ CG      S L+ H RTHT  +P+ C  C  AF TKGNL  HM
Sbjct: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHM 1160



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 21/50 (42%), Positives = 27/50 (54%)

Query: 193  ICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242
            +C  C +P A  S L+ H RSHT ERP+ C  C     T  NL +H  +H
Sbjct: 978  VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 81/339 (23%), Positives = 119/339 (35%), Gaps = 44/339 (12%)

Query: 1837 EGSEAVEEHQFSDLEDSDSDSDLDEDEDEDE---EESQDELSRPSSEAPPPG--PPHALR 1891
            E + A     F +   + S S+  E E  +E   E ++ E      EA P    P    R
Sbjct: 84   EDAPAPPPEDFPEPSPASSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTR 143

Query: 1892 ADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVE 1951
            A   P   P PP  PA G  +T  +     E L ++  +++  S       G    G   
Sbjct: 144  APRPPPAAPAPP-TPAYGAPSTNVT----LEALLSTKVAVAQFSQ------GARAAGGSG 192

Query: 1952 KDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKH----SLTKNDSSPQRCSPAREPQASA 2007
               G A +  P+   +  +  ++   +  L  +     +L +        SPA  P A  
Sbjct: 193  AGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPG 252

Query: 2008 PSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLE-GTTDPGLPRY 2066
            P+P  L   PG     L  G+P   ++     P        A  LS+ E G + PG P  
Sbjct: 253  PAPSQL---PGLAALPLSAGAPAAAIAGSG--PAAPAAFEGAQPLSRPESGASTPGGPA- 306

Query: 2067 SPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSR 2126
             P+   +P  A +P   AP        P   SA    P          PPA  P  LL  
Sbjct: 307  EPSAPAAPSAAPAPAAPAP-------APAPQSAASSQP-----QSASTPPALAPGSLLGA 354

Query: 2127 SPETCASPWKAESRSPSCSPGPAHPLSSR-----PFSAL 2160
            +P   +      S S    P P   +++      P SAL
Sbjct: 355  APGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSAL 393


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 185/906 (20%), Positives = 311/906 (34%), Gaps = 170/906 (18%)

Query: 748  NLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFE 807
            ++P  + +SP+   K       P     R P PG  ++ G  +  T+             
Sbjct: 70   SVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTT------------- 116

Query: 808  KSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAH--SLQPKLVRQPNIQVPEILVTEEPD 865
              D+      L G                 +  H  S+ P  + + N       V  + +
Sbjct: 117  --DTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFN 174

Query: 866  RPDTEPEPPPKEPEKTEEFQWPQRSQT----LAQLPAEKLPPKKKRLRLAEMAQSSGESS 921
              D   +    + E T++ +  Q+ Q     + + P ++ PPK                 
Sbjct: 175  PFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKP---------------- 218

Query: 922  FESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSH 981
                +P  + P ++  +   G+ +S S ++ +  K++ P        KP+     T  + 
Sbjct: 219  ----IPKQQGPGRDP-LQQDGTPKSISSQQPEKIKSQPPGTG-----KPIQGPTQTPQTD 268

Query: 982  H---PHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGP----------SAPAP 1028
            H   P  R+  R  ++Q+  V   +      S S         G           S P P
Sbjct: 269  HAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP 328

Query: 1029 VAPPAR--------------VAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQP 1074
              PPA+              V PP       V+    ++PP   L  A    Q++   +P
Sbjct: 329  AKPPAQPSGLTKPLAQQPGTVKPP-------VQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381

Query: 1075 SSSKPSAKSSLSQISSAATSHGGPPG-GKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPL 1133
            SS +P  K+ L+Q          PPG GK P Q     GP  P T+ +     P+AQ P 
Sbjct: 382  SSEQPGPKA-LAQ----------PPGVGKTPAQQP---GPAKPPTQQVGT-PKPLAQQPG 426

Query: 1134 HEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAP---- 1189
             + P   P  +    Q   Q  PG+ P   + QA     S+  + P  PPS    P    
Sbjct: 427  LQSPAKAPGPTKTPVQ---QPGPGKIP---AQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480

Query: 1190 ---PLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQF 1246
               P P +P    PG    P   P     P +QP    P P    S              
Sbjct: 481  PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS--------- 531

Query: 1247 ALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLA 1306
              Q PG  +    Q  +   P A  S      T     ++ P V+P A        P   
Sbjct: 532  --QQPGSAKPSAQQ-PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588

Query: 1307 LPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGT 1366
             P C  T + L VP +   N          T  Q  V    G +    L + +E      
Sbjct: 589  CPLCNTTELLLHVPEKANFNT--------CTECQTTVCSLCGFNPNPHLTEVKEWLCLNC 640

Query: 1367 TVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESI----------- 1415
             +  A   ++ P PS    +   A  T    V  + P+ + TS   ++            
Sbjct: 641  QMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEP 700

Query: 1416 ---------LSLEGSSSTAG----GSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKL 1462
                      +L GS S        +  +  PA   E ++ ++Q K    ++  K   + 
Sbjct: 701  KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPK---QP 757

Query: 1463 ELVKPCSVVLTSTEDGKRPEKSHLGNQGQG-RRELEMLSSLSSDPSDT-----KEIPPLP 1516
            ++VKP + +++S+    +P+      Q Q   +    L + S+ PS +     +++ P  
Sbjct: 758  KMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD 817

Query: 1517 HPALSHGTAPGSEA-LKEYPQPSGKPH-RRGLTPLSVKKEDSKEQPDLPSLAPPSSLPLS 1574
              A+     P S++ +  +P PS +   ++ + P+  K+E  K Q  +     P + P+ 
Sbjct: 818  SKAIPR---PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMS--PKPDAKPMP 872

Query: 1575 ETSSRP 1580
            + S  P
Sbjct: 873  KGSPTP 878



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 105/449 (23%), Positives = 166/449 (36%), Gaps = 102/449 (22%)

Query: 1971 PSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPR 2030
            P ++   R PL       + D +P+  S +++P+     PPG    P +G    P  +P+
Sbjct: 220  PKQQGPGRDPL-------QQDGTPKSIS-SQQPEKIKSQPPGTG-KPIQG----PTQTPQ 266

Query: 2031 LQLSPLTLCPLGRELA-PRAHVLSKLEG-TTDPGLPRYS--PTRRWSPGQAESPPRSAPP 2086
               + L   PL R+ + P+      + G +  P LP  S  P ++ +PG+   PP   P 
Sbjct: 267  TDHAKL---PLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK---PPAQQPG 320

Query: 2087 GKWALAGPGSPSAGEHG--PGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSC 2144
             + +  GP  P A   G    L   P  + PP   P                  ++ P+ 
Sbjct: 321  HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP----------------GTTKPPAQ 364

Query: 2145 SPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQA 2204
              GPA P +                   +   S  P   Q   +A      +G     Q 
Sbjct: 365  PLGPAKPPA-------------------QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP 405

Query: 2205 RPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTL 2264
             P   PT   G                T    AQ+ G  SP ++   + +PV +     +
Sbjct: 406  GPAKPPTQQVG----------------TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449

Query: 2265 SSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTH-SPCTPPDTLP---RPPQG 2320
             ++  G   P +      GP +PP   P     PA+P P    P  PP   P   +PP  
Sbjct: 450  PAQQAG---PGKTSAQQTGPTKPPSQLP----GPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502

Query: 2321 RRAAQSWSPRLESPRAPTNPEPSAT-PPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQ 2379
            +  +    P+   P  P+  +P +T PP  +  S    A+ SA+ P+  +       + Q
Sbjct: 503  QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS----AKPSAQQPSPAK------PSAQ 552

Query: 2380 DSPKP---SGSGEPRAHPH-QPEDRVPPN 2404
             S KP   +GSG+P   P   P  + PP+
Sbjct: 553  QSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 178/861 (20%), Positives = 293/861 (34%), Gaps = 120/861 (13%)

Query: 803  TSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTE 862
            TS+  KS    Q +  + +  P  Q  S  P P         P LV+QP +        +
Sbjct: 669  TSAVSKSSPQPQQTSPKKDAAP-KQDLSKAPEP------KKPPPLVKQPTLHGSPSAKAK 721

Query: 863  EPDRPDTEPEP-PPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESS 921
            +P   D+  +P PPKEP    E       Q  A +  +K P + K ++      SS  ++
Sbjct: 722  QPPEADSLSKPAPPKEPSVPSE-------QDKAPVADDK-PKQPKMVKPTTDLVSSSSAT 773

Query: 922  FESSVPLSRSPSQ---ESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTV 978
             +  +P S+  SQ   ++   L   S   S      G+  +P  S  +      + +++ 
Sbjct: 774  TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISH 833

Query: 979  P---SHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGP------SAPAPV 1029
            P   S     +++     ++ P  + +    +  +K    GS +  GP      + P P 
Sbjct: 834  PGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQ 893

Query: 1030 APPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQIS 1089
              P    P E+ + F +   S++  P+S+    P   QE+   +      S  S  S + 
Sbjct: 894  QSP---KPQEQSRRFSLNLGSITDAPKSQ----PTTPQETVTGKLFGFGASIFSQASNLI 946

Query: 1090 SAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPP-PVSLFSF 1148
            S A    GP    GPG          P  +A      P +Q P       PP P      
Sbjct: 947  STA-GQPGPHSQSGPG---------APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996

Query: 1149 QHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPL---PPSLFQAPPLPLQPTVLH--PGQL 1203
            +   +    +  E  + QA +   +     PP      SL   P   + PT L   P   
Sbjct: 997  KKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056

Query: 1204 HLPQLMPHPANIPFRQPPSFLPM--------------PYPTSSALSSGFFLPLQSQFAL- 1248
                L     NI  + PP+F                 P P  + +     L  Q+Q A+ 
Sbjct: 1057 STCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116

Query: 1249 -QLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSD-IRLPP---VAPPASSSAPTSAP 1303
             QL GD+    P      AP    ++ +   TE SS    +PP   +         T A 
Sbjct: 1117 GQL-GDIRKMPP------APSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAE 1169

Query: 1304 PLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQI------------LVTQSQGSSA 1351
             + L    +T+    +P  V T+     S +    +              L+ + +   +
Sbjct: 1170 KVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRS 1229

Query: 1352 TVALPKFEEP----------PSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVT 1401
                P  EE           P   T+      H++      ++EE+      P       
Sbjct: 1230 EEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGK 1289

Query: 1402 LPERKGTSLSSESILSL--EGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKAD 1459
             P+ K   L S +  SL  E   +T    ++   P  +    +E  ++K  KE++ S   
Sbjct: 1290 QPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTS 1349

Query: 1460 EKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQ--GRRELEMLSSLSSD-------PSDTK 1510
               +   P    L+ T        S LG         E ++L  L  D       PS   
Sbjct: 1350 SSQQPKSPQG--LSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPS 1407

Query: 1511 EIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSS 1570
            ++  L    LS   A  S    E  +   +PH        V  E  K+Q    SL+    
Sbjct: 1408 DLAKLESTVLSILEAQASTLADEKSEKKTQPH-------EVSPEQPKDQEKTQSLSETLE 1460

Query: 1571 LPLSETSSRPAKSQEGTDSKK 1591
            + +SE   + ++ +     KK
Sbjct: 1461 ITISEEEIKESQEERKDTFKK 1481



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 180/827 (21%), Positives = 265/827 (32%), Gaps = 129/827 (15%)

Query: 673  KPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFES 732
            KPI   T T       Q +H             T +   +R    + SL    +PP  + 
Sbjct: 256  KPIQGPTQTP------QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309

Query: 733  TKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKP------------ 780
            T      PG   A +    +S   PA+P      L  P   QP T KP            
Sbjct: 310  T------PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363

Query: 781  -----------GSGSESGKERRTTSKEISVIQHT--SSFEKSDSLEQPSGLEGEDKPLAQ 827
                        +GSE     +   K ++       +  ++    + P+   G  KPLAQ
Sbjct: 364  QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423

Query: 828  FP---SPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEP-------EPPPKE 877
             P   SP  AP        QP   + P  Q      + +   P   P       +PPP++
Sbjct: 424  QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQ 483

Query: 878  PEKTE-EFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPS--Q 934
            P   +   Q P  ++  +Q P    PP ++        Q  G +   S  P S  PS  Q
Sbjct: 484  PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543

Query: 935  ESNVSLSGSSRSASFERDDHGKAEAP---SPSSDMRPK--------PLGTHMLTVPSHHP 983
             S    S    +    +   GK   P   SPS+   P         PL  +   +  H P
Sbjct: 544  PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPL-CNTTELLLHVP 602

Query: 984  HAREMRRSASEQSP-----NVSHSAHMTETRSKSFDYGSL--SLTGPSAPAPVAP-PARV 1035
                       Q+        + + H+TE +        +  +L G  AP P +P P   
Sbjct: 603  EKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLK 662

Query: 1036 APPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSH 1095
              P      + + +   +    + + APK +  S+ P+P    P  K      S +A + 
Sbjct: 663  TAPVTTTSAVSKSSPQPQQTSPKKDAAPK-QDLSKAPEPKKPPPLVKQPTLHGSPSAKAK 721

Query: 1096 GGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLV--- 1152
              PP      +  PP  P+VP  +       PVA     +   + P   L S        
Sbjct: 722  -QPPEADSLSKPAPPKEPSVPSEQD----KAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776

Query: 1153 ---------QHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPT--VLHP- 1200
                     Q E   +P   +  A  S  S P +   + P   +A P P   +  + HP 
Sbjct: 777  DIPSSKVQSQAEEKTTPPLKTDSAKPS-QSFPPTGEKVSPFDSKAIPRPASDSKIISHPG 835

Query: 1201 ------GQLHLPQLM----PHPANIPFRQPPSFLPM----PYPTSSALSSGFFLPLQSQ- 1245
                  GQ  +  +     P  A       P   PM    P P     ++G  +P   Q 
Sbjct: 836  PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQS 895

Query: 1246 ---------FALQLPGDVESHLPQIKTSLAPLATGSA---GLSPSTEYSSDIRLPPVAPP 1293
                     F+L L G +        T+     TG     G S  ++ S+ I       P
Sbjct: 896  PKPQEQSRRFSLNL-GSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGP 954

Query: 1294 ASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATV 1353
             S S P  AP    PA          P   Q    S G A       I V +   + A  
Sbjct: 955  HSQSGP-GAPMKQAPAPSQ-------PPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAE 1006

Query: 1354 AL-PKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVP 1399
             L PK E+ P+   T        +    S  +E Q    PT   + P
Sbjct: 1007 KLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053



 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 136/588 (23%), Positives = 201/588 (34%), Gaps = 103/588 (17%)

Query: 1865 EDEEESQDELSRPSSEAPPPGPPHALRAD---SSPILGPQPPDAPASGTEATRGSSVSEA 1921
            E  + S    S+P  + P PG P A +     S P  GP  P A  SG            
Sbjct: 292  ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP--GPAKPPAQPSGLTKPLAQQPGTV 349

Query: 1922 ERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPL 1981
            +              PG       PLG  +       S KP S +    P  +A ++PP 
Sbjct: 350  K---------PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ----PGPKALAQPPG 396

Query: 1982 ARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPL 2041
              K       +  Q+  PA+ P     +P  L   PG      P  +P    +P+     
Sbjct: 397  VGK-------TPAQQPGPAKPPTQQVGTPKPLAQQPGLQS---PAKAPGPTKTPVQQPGP 446

Query: 2042 GRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGE 2101
            G+  A +A         T P  P   P++   PG A+ PP+   P K     PGS     
Sbjct: 447  GKIPAQQAGPGKTSAQQTGPTKP---PSQL--PGPAKPPPQQPGPAKPPPQQPGSAKPPS 501

Query: 2102 HGPGLGLDPRVLFPPAPLPHKLLSRSPETCASP-WKAESRSPSC-SPGPAHP---LSSRP 2156
              PG    P    P  P P K   + P +   P  +  S  PS   P PA P    S++P
Sbjct: 502  QQPGSTKPP----PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557

Query: 2157 FSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQM-VQARPGAHPTLLPG 2215
             S      G  L     +  +  P  SQ L +  CPL     + + V  +   +      
Sbjct: 558  VSQTGS--GKPLQPPTVSPSAKQP-PSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQ 614

Query: 2216 PTAAWVSGFSGGGSDLTGARE-----AQER----GRWSPTESSS---------ASVSPVA 2257
             T   + GF+     LT  +E      Q +    G  +P  SS           + S V+
Sbjct: 615  TTVCSLCGFN-PNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVS 673

Query: 2258 KVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGT--GAP-------------AEPT 2302
            K S     +  +    PK+       P +PP      T  G+P             ++P 
Sbjct: 674  KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733

Query: 2303 PTHSPCTP--------PDTLPRPPQGRR--------AAQSWSPRLESPRAPTNPEPSATP 2346
            P   P  P         D  P+ P+  +        ++ +  P + S +  +  E   TP
Sbjct: 734  PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793

Query: 2347 PLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHP 2394
            PL   S     A+ S  FP     +S  P   +  P+P+   +  +HP
Sbjct: 794  PLKTDS-----AKPSQSFPPTGEKVS--PFDSKAIPRPASDSKIISHP 834



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 245/1192 (20%), Positives = 368/1192 (30%), Gaps = 262/1192 (21%)

Query: 30   SVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEAS 89
            SV  S+P P        + P Q     QP PG     + G +    + Q  P +PP + S
Sbjct: 293  SVKPSLPSPS-------KPPIQ-----QPTPGKPPAQQPGHE----KSQPGPAKPPAQPS 336

Query: 90   VHISQLPQHPLT-------------PAF-MSPGKPEHLLEGSTWQLVDPMRPGPSGSFVA 135
                 L Q P T             PA  + P KP     GS  +     +PGP      
Sbjct: 337  GLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGS--EKPSSEQPGPKALAQP 394

Query: 136  PGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQ 195
            PG+       P  A   PP    G PK    +P   S        K   +   PGK   Q
Sbjct: 395  PGVGKTPAQQPGPAK--PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452

Query: 196  YCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMG 255
                   K S  Q        + P P  P              +        A   S   
Sbjct: 453  QAGP--GKTSAQQTGPTKPPSQLPGPAKP------PPQQPGPAKPPPQQPGSAKPPSQQP 504

Query: 256  GEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGLYSSG 315
            G   P   +    PG     P +  S      T   S  P    P  +QP       S  
Sbjct: 505  GSTKPPPQQ----PGPAKPSPQQPGS------TKPPSQQPGSAKPSAQQP-------SPA 547

Query: 316  SHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSH-KPEDTHTIKQKLALRLSERKKV 374
              S+      +SQ+ + + L+  PP V PS++ P S   P+    +     L L      
Sbjct: 548  KPSAQQSTKPVSQTGSGKPLQ--PPTVSPSAKQPPSQGLPKTICPLCNTTELLLH----- 600

Query: 375  IDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTA 434
            + E+A  +  ++  T     +         +P  T  K +  +       +G   A +  
Sbjct: 601  VPEKANFNTCTECQT-----TVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPV-P 654

Query: 435  TSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRR 494
            +S QP L  +     S V  S P+ Q                 TS      P++  LS+ 
Sbjct: 655  SSPQPKLKTAPVTTTSAVSKSSPQPQ----------------QTSPKKDAAPKQ-DLSKA 697

Query: 495  SSMESPKSSLYREPL--SSHSEKTK--PEQSLLSLQHPPSTAPPVP-------------- 536
               + P   L ++P    S S K K  PE   LS   PP   P VP              
Sbjct: 698  PEPKKP-PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK-EPSVPSEQDKAPVADDKPK 755

Query: 537  ----LLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKR--- 589
                +  +  + S++   + P  P     S  +  T     + S+    S P   ++   
Sbjct: 756  QPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP 815

Query: 590  --QPAIELPLGGEYSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNI 647
                AI  P         PGPSS+    K  D V+ KE     +TK   K          
Sbjct: 816  FDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD-------- 867

Query: 648  CGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTL 707
                                    AKP+  G+ T P    +  +  P  Q          
Sbjct: 868  ------------------------AKPMPKGSPTPPGPRPTAGQTVPTPQQS-------- 895

Query: 708  ELTPLRKRRKEKSLGDEEEPPAFESTKSQ---------FGSPGPSDAARNLPLESTKSP- 757
                 + RR   +LG   + P  + T  Q         FG+   S A+  +       P 
Sbjct: 896  PKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPH 955

Query: 758  AEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSG 817
            ++     P  + P   QP T + G    +G+     +K I V + T +   ++ LE  + 
Sbjct: 956  SQSGPGAPMKQAPAPSQPPTSQ-GPPKSTGQAPPAPAKSIPVKKETKA-PAAEKLEPKAE 1013

Query: 818  LEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEP------ 871
                 K       PPP    +S       L  +P   V    + + P    T P      
Sbjct: 1014 QAPTVKRTETEKKPPPIKDSKS-------LTAEPQKAVLPTKLEKSPKPESTCPLCKTEL 1066

Query: 872  ----EPPPK-------------------EPEKTEEFQW------PQRSQTLAQLPAEKLP 902
                + PP                     P  TE  +W       QR+ +       K+P
Sbjct: 1067 NIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP 1126

Query: 903  PKKKRLRLAEMAQSSGESSFESSVP----LSRSPSQE-----SNVSLSGSSRSASFE--- 950
            P     + + M   +  SS +++VP    L +   QE       V L     + S E   
Sbjct: 1127 PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIP 1186

Query: 951  -------RDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSA 1003
                   + +  K E    S+    KPL      +P       E +  + E+ P +    
Sbjct: 1187 PMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIP------EEEKIRSEEKKPLLEEKK 1240

Query: 1004 HMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAP 1063
               E +                   + P A+ + PE +K  L++        + E  VAP
Sbjct: 1241 PTPEDKK------------------LLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAP 1282

Query: 1064 KGRQESEEPQ------PSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRP 1109
            K  QE ++PQ      PS +  S      + +        PP    P Q  P
Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP 1334



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 204/1046 (19%), Positives = 347/1046 (33%), Gaps = 163/1046 (15%)

Query: 26   AIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPP 85
            A Q  + S    PG      Q+    ++ A Q  PG +S  + G  +   Q   P K PP
Sbjct: 422  AQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP 481

Query: 86   IEASVHISQLPQHPLTPAFMSPG--KPEHLLEGSTWQLVDPMRPGPS-------GSFVAP 136
             +           P  P    PG  KP     GST     P +PGP+       GS   P
Sbjct: 482  QQPG---------PAKPPPQQPGSAKPPSQQPGST--KPPPQQPGPAKPSPQQPGSTKPP 530

Query: 137  GLHP----QSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKY 192
               P     S   PS A     +    V +    +P Q    PT     K+   Q   K 
Sbjct: 531  SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ---PPTVSPSAKQPPSQGLPKT 587

Query: 193  ICQYCSRPCAKPSVLQK-HIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLA 251
            IC  C+       V +K +  + T  +   C  CGF+     N +         +   + 
Sbjct: 588  ICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN----PNPHLTEVKEWLCLNCQMK 643

Query: 252  SGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGL 311
              +GG++ P       +P      P     T     TSA S    + SP+P+Q       
Sbjct: 644  RALGGDLAP-------VP----SSPQPKLKTAPVTTTSAVS----KSSPQPQQT------ 682

Query: 312  YSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEH----PLSHKPEDTHTI------K 361
                  S   +       S A   + PPP V+  + H      + +P +  ++      K
Sbjct: 683  ------SPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK 736

Query: 362  QKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGK 421
            +       ++  V D++       K +T+      S SA  +   P++  +S AE     
Sbjct: 737  EPSVPSEQDKAPVADDKPKQPKMVKPTTD---LVSSSSATTKPDIPSSKVQSQAE----- 788

Query: 422  CGRIGQRTAMLTATSTQP--LLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTS 479
                 + T  L   S +P    P + E        ++PR      I      +       
Sbjct: 789  ----EKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844

Query: 480  EIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLR 539
            ++D V+ +      ++ M SPK      P  S +       +  ++  P  +  P    R
Sbjct: 845  QVDPVQKKEEPKKAQTKM-SPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSR 903

Query: 540  SHSMPSAACT------ISTPHHPFRGS-YSFDDHITD------SEALSHSSHVFTSHPRM 586
              S+   + T       +TP     G  + F   I        S A     H  +     
Sbjct: 904  RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963

Query: 587  LKRQPAIELPLGGEYSSEEPG----------PSSKDTASKPSDEVEP--------KESEL 628
            +K+ PA   P   +   +  G          P  K+T +  ++++EP        K +E 
Sbjct: 964  MKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTET 1023

Query: 629  TKKTKKGLKTKGVIYECN--ICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAE 686
             KK      +K +  E    +   + +K    E+      +EL I        +T  E +
Sbjct: 1024 EKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECK 1083

Query: 687  KSQIEHEPWSQMMHY-KLGTTLELTPLRKRRKEKSLGDEEEPPAFESTKSQFGSPGPSDA 745
                    ++   H  ++   L L    +R     LGD  + P   S       P P+++
Sbjct: 1084 NQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTES 1143

Query: 746  A----------RNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSK 795
            +          + +  +  +   E  K +      T    + P   +  +  +E +    
Sbjct: 1144 SSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKD 1203

Query: 796  EISVIQHTSSFEKSDSL--EQPSGLEGEDKPLAQFPSPPP-----APHGR-SAHSLQPKL 847
            + S +Q      +   L  E+      E KPL +   P P      P  + SA   Q   
Sbjct: 1204 KASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD 1263

Query: 848  VRQPNIQVPEILV--------TEEPDRPDTE--------PEPPPKEPEKTEEFQWPQRSQ 891
            + +  +Q+ E  +         +E  +P T+        P+  PKE +KT +    Q   
Sbjct: 1264 LLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQP 1323

Query: 892  TLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLS-GSSRS---- 946
                 P +  P K+K  +  + + +S     +S   LS +      +S S G   S    
Sbjct: 1324 PCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPT 1383

Query: 947  ------ASFERDDHGKAEAPSPSSDM 966
                     ++D   +  +PS  SD+
Sbjct: 1384 DEKDILKGLKKDSFSQESSPSSPSDL 1409



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 142/626 (22%), Positives = 218/626 (34%), Gaps = 132/626 (21%)

Query: 1873 ELSRPSSEAPPPG---PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSC 1929
            ++  P   A  PG   P  A     +P+  P P   PA   +A  G + ++    T    
Sbjct: 414  QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ--QAGPGKTSAQQTGPTKPPS 471

Query: 1930 SMSSQSMPGLPWLGPAPL-----GSVEKDTGSALSYKPV---------SPRRPWS---PS 1972
             +   + P     GPA       GS +  +    S KP          SP++P S   PS
Sbjct: 472  QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531

Query: 1973 KEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQ 2032
            ++ GS  P A++ S  K  S+ Q   P  +  +  P  P   V P           P  Q
Sbjct: 532  QQPGSAKPSAQQPSPAK-PSAQQSTKPVSQTGSGKPLQPPT-VSPS-------AKQPPSQ 582

Query: 2033 LSPLTLCPLGRELAPRAHVLSKLEGTT--------------DPGLPRYSPTRRWSPGQAE 2078
              P T+CPL        HV  K    T              +P  P  +  + W     +
Sbjct: 583  GLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPN-PHLTEVKEWLCLNCQ 641

Query: 2079 SPPRSAPPGKWALAGPGSPSAGEHGPGLGLDP----RVLFPPAPLPHKLLSRSPETCASP 2134
                     K AL G  +P      P L   P      +   +P P +    SP+  A+P
Sbjct: 642  M--------KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQT---SPKKDAAP 690

Query: 2135 WKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLI 2194
             +  S++P     P  PL  +P       HG   A+ ++      P  +  L++   P  
Sbjct: 691  KQDLSKAPEPKKPP--PLVKQP-----TLHGSPSAKAKQ------PPEADSLSKPAPPKE 737

Query: 2195 PIGGIQMVQARPGAHPTLLPG---PTAAWVSGFSGGGS-DLTGAR-EAQERGRWSP---T 2246
            P    +  +A         P    PT   VS  S     D+  ++ ++Q   + +P   T
Sbjct: 738  PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKT 797

Query: 2247 ESSSASVS--PVA-KVSKFTL------------------SSELEGGDY-----PKERERT 2280
            +S+  S S  P   KVS F                    SSE +G         KE  + 
Sbjct: 798  DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857

Query: 2281 GGGPGRP-PDWTPHGTGAPAE--PTPTHSPCTP-PDTLPRP-PQGRRAAQSWSPRLESPR 2335
                  P PD  P   G+P    P PT     P P   P+P  Q RR + +     ++P+
Sbjct: 858  AQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK 917

Query: 2336 A-PTNPEPSATPPL---------------DRSSSVGCLAEASARFPARTRNLSGEPRTRQ 2379
            + PT P+ + T  L                 +   G  +++    P +      +P T Q
Sbjct: 918  SQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQ 977

Query: 2380 DSPKPSGSGEP---RAHPHQPEDRVP 2402
              PK +G   P   ++ P + E + P
Sbjct: 978  GPPKSTGQAPPAPAKSIPVKKETKAP 1003



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 155/751 (20%), Positives = 250/751 (33%), Gaps = 117/751 (15%)

Query: 228  SFKTKSNLYKHRKSHAHRIKAGLASGMGGEMYPH-----GLEMERIPGEEFEEPTEGEST 282
            + K+   +Y+      H+ KA  A+    E++       G+ +E    E   E T   S 
Sbjct: 1910 ALKSAEEMYEEMMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSV 1969

Query: 283  DSEEETSATSGHP-AELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPF 341
            D    T     +   +   R ++  LS  +Y       +  +    +  +  S+      
Sbjct: 1970 DGSLLTRQEEENGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDI 2029

Query: 342  VEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAE 401
            V  S   P SH+  D  T    +     E +K++D  A             Y    +  +
Sbjct: 2030 VSSSFIIPESHEIVDLGT----MVTSTEEERKLLDADA------------AYEELMKRQQ 2073

Query: 402  QQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQV 461
             Q++P ++  ++       +      R    + TS+  L   S  D  S   LS+P  ++
Sbjct: 2074 MQLTPGSSPTQAPIGEDMTESTMDFDRMPDASLTSSV-LSGASLTDSTSSATLSIPDVKI 2132

Query: 462  IEHITKLITINEAVVD-TSEIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQ 520
             +H +     +E V D T EI  +    S +             Y EP  S S  + P  
Sbjct: 2133 TQHFSTEEIEDEYVTDYTREIQEIIAHESLILT-----------YSEP--SESATSVPPS 2179

Query: 521  SLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHV- 579
                    PS    V  + +    S   T+ +    +           DSE +S S++  
Sbjct: 2180 DT------PSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFP 2233

Query: 580  --FTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDTASKPSDEVEPK------------- 624
                 +P  +        P  G  S++    S  D AS   + V PK             
Sbjct: 2234 GSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDL 2293

Query: 625  ---ESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHT 681
               E +  KK KK     G+I E       Y+ +   EA +                  T
Sbjct: 2294 LISEKDPVKKAKKETGN-GIILEVL---EAYRDKKELEAER------------------T 2331

Query: 682  SPEAEKSQIEHEPWSQM---MHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFESTKSQFG 738
                 ++  +H P S +   M  +L TT   T      +EK     + P    S  S   
Sbjct: 2332 KSSLSETVFDHPPSSVIALPMKEQLSTTY-FTSGETFGQEKPAS--QLPSGSPSVSSLPA 2388

Query: 739  SPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEIS 798
             P P   + +L + +   P  P    P    P    P  P P S   +   ++  +    
Sbjct: 2389 KPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASP 2448

Query: 799  VIQHTSSFEKSDSLEQPSGLEGEDKPLAQF--PSPPPAPHGRSAHSLQPKLVRQPNIQVP 856
            V   T  F+   +LE  + L     P+ +    +PPP P         PK    P+    
Sbjct: 2449 VTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVP---------PK----PSSIPS 2495

Query: 857  EILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQS 916
             ++ T  P     EP  PP  P+       PQ   T  Q P + + PK   L L      
Sbjct: 2496 GLVFTHRP-----EPSKPPIAPKPV----IPQ-LPTTTQKPTD-IHPKPTGLSLTSSMTL 2544

Query: 917  SGESSFESSVPLSRSP-SQESNVSLSGSSRS 946
            +  +S +  +P   SP S  SN S    S+S
Sbjct: 2545 NLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 117/557 (21%), Positives = 188/557 (33%), Gaps = 75/557 (13%)

Query: 1181 LPPSLFQAPPLPLQPTVLHPGQLHLPQ-------LMPHPANIPFRQPPSFLPMPYPTSSA 1233
            + P L Q PP P+ P    PG+  L Q           P  I  + P +  P+  PT + 
Sbjct: 207  IKPPLQQQPPKPI-PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTP 265

Query: 1234 LSSGFFLPLQ--------SQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDI 1285
             +    LPLQ         Q  +     V+  LP    S  P+   + G  P+ +   + 
Sbjct: 266  QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS--PSKPPIQQPTPGKPPAQQPGHEK 323

Query: 1286 RLP-PVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVT 1344
              P P  PPA  S  T   PLA    P T+   V P    T  P+         +Q   T
Sbjct: 324  SQPGPAKPPAQPSGLTK--PLAQQ--PGTVKPPVQPPGT-TKPPAQPLGPAKPPAQ--QT 376

Query: 1345 QSQGSSATVALPK-FEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLP 1403
             S+  S+    PK   +PP  G T          PGP+          PT  +  P  L 
Sbjct: 377  GSEKPSSEQPGPKALAQPPGVGKTPAQQ------PGPAKP--------PTQQVGTPKPLA 422

Query: 1404 ERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLE 1463
            ++ G          L+  +   G +K  +   G  ++  +     +   ++        +
Sbjct: 423  QQPG----------LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472

Query: 1464 LVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALSHG 1523
            L  P            +P     G      ++       S  P  TK  P  P PA    
Sbjct: 473  LPGPA-----------KPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP 521

Query: 1524 TAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSSLPLSETSSRPAKS 1583
              PGS         S KP  +  +P     + S +Q   P     S  PL   +  P+  
Sbjct: 522  QQPGSTKPPSQQPGSAKPSAQQPSP----AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAK 577

Query: 1584 QEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVS 1643
            Q  +        P  +TT       L+  +  +        +     C    NP+L  V 
Sbjct: 578  QPPSQGLPKTICPLCNTTE----LLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVK 633

Query: 1644 TKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLA 1703
                L+  + K+ +  +   + ++P P+  +  P ++          P   SP  +KD A
Sbjct: 634  EWLCLN-CQMKRALGGDLAPVPSSPQPKL-KTAPVTTTSAVSKSSPQPQQTSP--KKD-A 688

Query: 1704 RVEKEEERRGEPEEDAP 1720
              +++  +  EP++  P
Sbjct: 689  APKQDLSKAPEPKKPPP 705



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 181/856 (21%), Positives = 289/856 (33%), Gaps = 138/856 (16%)

Query: 1    MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFP 60
            +DP Q  +  KKA+    K   K +A      S  P PG    A Q  P      PQ  P
Sbjct: 846  VDPVQKKEEPKKAQ---TKMSPKPDAKPMPKGSPTP-PGPRPTAGQTVPT-----PQQSP 896

Query: 61   GPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQL---------PQHPLTPAFMSPGKPE 111
             P    R  S         P  +P         +L             L      PG   
Sbjct: 897  KPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHS 956

Query: 112  HLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVP-KVFVPRPSQ 170
                G+      PM+  P     AP   P SQ  P      PP     +P K     P+ 
Sbjct: 957  QSGPGA------PMKQAP-----APSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAA 1005

Query: 171  VSLKP------TEEAHKKERKPQKPGKYICQYCSRP--CAKPSVLQKHIRSHTGERPYPC 222
              L+P      T +  + E+KP  P K      + P     P+ L+K         P P 
Sbjct: 1006 EKLEPKAEQAPTVKRTETEKKPP-PIKDSKSLTAEPQKAVLPTKLEKS--------PKPE 1056

Query: 223  GPCGFSFKTKSNLYKHRKSHAH---RIKAGLASGMGGEMYPHGLEMER--IPGEEFEEPT 277
              C    KT+ N+      + +     K  + +  G    PH  E++       + +   
Sbjct: 1057 STCPLC-KTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAI 1115

Query: 278  EGESTDSEEETSATSGHPAELSPRPKQ---------PLLSSGLYSSGSHSSSHERCSLSQ 328
             G+  D  +   A SG  A   P P +         P +           +  E+  L +
Sbjct: 1116 SGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEK 1175

Query: 329  SSTAQSLEDPPPFV-----------EPSSEHPLSHK---PEDTHTIKQKLALRLSERKKV 374
                 S+E  PP V           E      L  K   PE+   I ++  +R  E+K +
Sbjct: 1176 VKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPL 1235

Query: 375  IDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKC-GRIGQRTAMLT 433
            ++E+       K   E    +++ + E+Q    +   KS  +I   K  GR+  +T    
Sbjct: 1236 LEEKKPTPEDKKLLPE----AKTSAPEEQ---KHDLLKSQVQIAEEKLEGRVAPKTVQ-- 1286

Query: 434  ATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSR 493
                QP   +  E  PS  P S+P+    +  TK I        T++ D V+P +     
Sbjct: 1287 -EGKQPQTKM--EGLPSGTPQSLPKED--DKTTKTIKEQPQPPCTAKPDQVEPGK----E 1337

Query: 494  RSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTP 553
            ++  E  KS       +S S++ K  Q L    +            S S+      I T 
Sbjct: 1338 KTEKEDDKSD------TSSSQQPKSPQGLSDTGYSSDGI-------SSSLGEIPSLIPTD 1384

Query: 554  HHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDT 613
                      D    +S   S S         + K +  +   L  + S+     S K T
Sbjct: 1385 EKDILKGLKKDSFSQESSPSSPSD--------LAKLESTVLSILEAQASTLADEKSEKKT 1436

Query: 614  ASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAK 673
                    +PK+ E T+   + L+    I E  I  ++ +++D +   KK    ++  +K
Sbjct: 1437 QPHEVSPEQPKDQEKTQSLSETLEI--TISEEEIKESQEERKDTF---KKDSQQDIPSSK 1491

Query: 674  PISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFEST 733
                    S   +      EP+  +   +  +  E +P+ +R++  S+G       ++  
Sbjct: 1492 D---HKEKSEFVDDITTRREPYDSV---EESSESENSPVPQRKRRTSVGSSSS-DEYKQE 1544

Query: 734  KSQFGSPGPSDAARNLPLE-STKSPAEPSK-------SVPSLEGPTGFQPRTPKPGSGS- 784
             SQ GS    D  R   +E S    A  S+        +  +   T  Q +    G G  
Sbjct: 1545 DSQ-GSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKI 1603

Query: 785  ESGKERRTTSKEISVI 800
             +GK RR T K  + I
Sbjct: 1604 TAGKHRRLTRKSSTSI 1619



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 57/223 (25%), Positives = 82/223 (36%), Gaps = 29/223 (13%)

Query: 1217 FRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLS 1276
            F  PPS + +  P    LS+ +F   ++ F  + P    S LP    S++ L        
Sbjct: 2340 FDHPPSSV-IALPMKEQLSTTYFTSGET-FGQEKPA---SQLPSGSPSVSSLPAKPRPFF 2394

Query: 1277 PSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDT--------MVSLVVPVRVQTNMP 1328
             S+      + PP  PP     P   PP   P  P T           L V   V T  P
Sbjct: 2395 RSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454

Query: 1329 SYGSAMYTTLSQILVTQSQGSSATVALPKFEEP-PSKGTTVCGADVHEVGPGPSGLSEEQ 1387
             + +   TTL    V +S G   T        P P K +++    V    P PS     +
Sbjct: 2455 LFDAV--TTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPS-----K 2507

Query: 1388 SRAFPTPYL-RVPVTL-------PERKGTSLSSESILSLEGSS 1422
                P P + ++P T        P+  G SL+S   L+L  S+
Sbjct: 2508 PPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSA 2550



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 86/360 (23%), Positives = 129/360 (35%), Gaps = 83/360 (23%)

Query: 1107 DRPPLGP-TVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFST 1165
            D PP     +P  E L   +    +T   EKP    P    S   L    P +   FF +
Sbjct: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSL----PAKPRPFFRS 2396

Query: 1166 QAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLP 1225
             ++  + + P   PP PP     PP P  P                        PP   P
Sbjct: 2397 SSLD-ISAQPPPPPPPPP-----PPPPPPP------------------------PPPPPP 2426

Query: 1226 MPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDI 1285
            +P PTS   +    LP + +  +  P    + L    T+L   A   +   P T   +  
Sbjct: 2427 LPPPTSPKPT---ILP-KKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT-- 2480

Query: 1286 RLPPVAPPASSSAPT----------SAPPLA-LPACPDTMVSLVVPVRVQTNMPSYGSAM 1334
              PP  PP  SS P+          S PP+A  P  P    +   P  +       G ++
Sbjct: 2481 TAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPK--PTGLSL 2538

Query: 1335 YTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTP 1394
             ++++  LVT     SA   LP    P              + P  +  S   S++    
Sbjct: 2539 TSSMTLNLVT-----SADYKLPSPTSP--------------LSPHSNKSSPRFSKSLTET 2579

Query: 1395 YLRVPVTLPERKGT---SLSSESILSLE-GSSSTAGGSKR----VLSPAGSLELTMETQQ 1446
            Y  V +TLP   GT   S +S++I S   GS S    S      V+ P  ++E+ + ++Q
Sbjct: 2580 Y--VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQ 2637



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 46/161 (28%), Positives = 60/161 (37%), Gaps = 26/161 (16%)

Query: 2245 PTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPT 2304
            P+ S S S  P AK   F  SS L+    P         P  PP   P     P  P P 
Sbjct: 2377 PSGSPSVSSLP-AKPRPFFRSSSLDISAQPP--------PPPPPPPPP-----PPPPPPP 2422

Query: 2305 HSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARF 2364
              P  PP T P+P        +  P+ +   A  +P  +ATP  D  +++   A   +  
Sbjct: 2423 PPPPLPPPTSPKP--------TILPKKKLTVA--SPVTTATPLFDAVTTLETTAVLRSNG 2472

Query: 2365 PARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPPNA 2405
               TR  +  P      PKPS         H+PE   PP A
Sbjct: 2473 LPVTRICTTAP--PPVPPKPSSIPSGLVFTHRPEPSKPPIA 2511



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 38/172 (22%), Positives = 64/172 (37%), Gaps = 19/172 (11%)

Query: 1860 DEDEDEDEEESQDELSRPSSEAPPP----GPPHALRADSSPILGPQPPDAP----ASGTE 1911
            + D D    +     S P  +  P     G    LRADS+  L P PP +P    +  + 
Sbjct: 3570 EADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISP 3629

Query: 1912 ATRGSSVSEA----ERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRR 1967
             + G ++  A    E+      S      P +  + PA          + +  + +S  +
Sbjct: 3630 LSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPA------SPKTAKMMQRSMSDPK 3683

Query: 1968 PWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPA-REPQASAPSPPGLHVDPG 2018
            P SP+ +  SR P       T   S     S A ++ + + P+PP   +  G
Sbjct: 3684 PLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTG 3735



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 35/172 (20%), Positives = 56/172 (32%), Gaps = 14/172 (8%)

Query: 1877 PSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSM 1936
            P    PPP PP  L   +SP     P       +  T  + + +A     ++  + S  +
Sbjct: 2414 PPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGL 2473

Query: 1937 PGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQR 1996
            P       AP               PV P+    PS    +  P   K  +      PQ 
Sbjct: 2474 PVTRICTTAP--------------PPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQL 2519

Query: 1997 CSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPR 2048
             +  ++P    P P GL +     +  +     +L      L P   + +PR
Sbjct: 2520 PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPR 2571



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 65/285 (22%), Positives = 99/285 (34%), Gaps = 50/285 (17%)

Query: 1329 SYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQS 1388
            S  S   TT  Q +V + QG    +  P  ++ P K          + GPG   L ++  
Sbjct: 182  SEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIP------KQQGPGRDPLQQD-- 233

Query: 1389 RAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQK 1448
                              GT  S  S    +  S   G  K +  P      T +T   K
Sbjct: 234  ------------------GTPKSISSQQPEKIKSQPPGTGKPIQGPT----QTPQTDHAK 271

Query: 1449 RVKEEEASKADEK-LELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPS 1507
               + +AS+   K  ++V+  SV  +       P K  +     G+   +      S P 
Sbjct: 272  LPLQRDASRPQTKQADIVRGESVKPSLPS----PSKPPIQQPTPGKPPAQQPGHEKSQPG 327

Query: 1508 DTKEIPPLPHPALSHGTAPGSEALKEYPQPSG--KPHRRGLTPL------SVKKEDSKEQ 1559
              K  PP     L+   A     +K   QP G  KP  + L P       +  ++ S EQ
Sbjct: 328  PAK--PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ 385

Query: 1560 PDLPSLAPPSSLPLSETS----SRPAKSQEGTDSKKVLQFPSLHT 1600
            P   +LA P  +  +       ++P   Q GT  K + Q P L +
Sbjct: 386  PGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT-PKPLAQQPGLQS 429


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 185/906 (20%), Positives = 311/906 (34%), Gaps = 170/906 (18%)

Query: 748  NLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFE 807
            ++P  + +SP+   K       P     R P PG  ++ G  +  T+             
Sbjct: 70   SVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTT------------- 116

Query: 808  KSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAH--SLQPKLVRQPNIQVPEILVTEEPD 865
              D+      L G                 +  H  S+ P  + + N       V  + +
Sbjct: 117  --DTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFN 174

Query: 866  RPDTEPEPPPKEPEKTEEFQWPQRSQT----LAQLPAEKLPPKKKRLRLAEMAQSSGESS 921
              D   +    + E T++ +  Q+ Q     + + P ++ PPK                 
Sbjct: 175  PFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKP---------------- 218

Query: 922  FESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSH 981
                +P  + P ++  +   G+ +S S ++ +  K++ P        KP+     T  + 
Sbjct: 219  ----IPKQQGPGRDP-LQQDGTPKSISSQQPEKIKSQPPGTG-----KPIQGPTQTPQTD 268

Query: 982  H---PHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGP----------SAPAP 1028
            H   P  R+  R  ++Q+  V   +      S S         G           S P P
Sbjct: 269  HAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP 328

Query: 1029 VAPPAR--------------VAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQP 1074
              PPA+              V PP       V+    ++PP   L  A    Q++   +P
Sbjct: 329  AKPPAQPSGLTKPLAQQPGTVKPP-------VQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381

Query: 1075 SSSKPSAKSSLSQISSAATSHGGPPG-GKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPL 1133
            SS +P  K+ L+Q          PPG GK P Q     GP  P T+ +     P+AQ P 
Sbjct: 382  SSEQPGPKA-LAQ----------PPGVGKTPAQQP---GPAKPPTQQVGT-PKPLAQQPG 426

Query: 1134 HEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAP---- 1189
             + P   P  +    Q   Q  PG+ P   + QA     S+  + P  PPS    P    
Sbjct: 427  LQSPAKAPGPTKTPVQ---QPGPGKIP---AQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480

Query: 1190 ---PLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQF 1246
               P P +P    PG    P   P     P +QP    P P    S              
Sbjct: 481  PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS--------- 531

Query: 1247 ALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLA 1306
              Q PG  +    Q  +   P A  S      T     ++ P V+P A        P   
Sbjct: 532  --QQPGSAKPSAQQ-PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588

Query: 1307 LPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGT 1366
             P C  T + L VP +   N          T  Q  V    G +    L + +E      
Sbjct: 589  CPLCNTTELLLHVPEKANFNT--------CTECQTTVCSLCGFNPNPHLTEVKEWLCLNC 640

Query: 1367 TVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESI----------- 1415
             +  A   ++ P PS    +   A  T    V  + P+ + TS   ++            
Sbjct: 641  QMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEP 700

Query: 1416 ---------LSLEGSSSTAG----GSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKL 1462
                      +L GS S        +  +  PA   E ++ ++Q K    ++  K   + 
Sbjct: 701  KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPK---QP 757

Query: 1463 ELVKPCSVVLTSTEDGKRPEKSHLGNQGQG-RRELEMLSSLSSDPSDT-----KEIPPLP 1516
            ++VKP + +++S+    +P+      Q Q   +    L + S+ PS +     +++ P  
Sbjct: 758  KMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD 817

Query: 1517 HPALSHGTAPGSEA-LKEYPQPSGKPH-RRGLTPLSVKKEDSKEQPDLPSLAPPSSLPLS 1574
              A+     P S++ +  +P PS +   ++ + P+  K+E  K Q  +     P + P+ 
Sbjct: 818  SKAIPR---PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMS--PKPDAKPMP 872

Query: 1575 ETSSRP 1580
            + S  P
Sbjct: 873  KGSPTP 878



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 105/449 (23%), Positives = 166/449 (36%), Gaps = 102/449 (22%)

Query: 1971 PSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPR 2030
            P ++   R PL       + D +P+  S +++P+     PPG    P +G    P  +P+
Sbjct: 220  PKQQGPGRDPL-------QQDGTPKSIS-SQQPEKIKSQPPGTG-KPIQG----PTQTPQ 266

Query: 2031 LQLSPLTLCPLGRELA-PRAHVLSKLEG-TTDPGLPRYS--PTRRWSPGQAESPPRSAPP 2086
               + L   PL R+ + P+      + G +  P LP  S  P ++ +PG+   PP   P 
Sbjct: 267  TDHAKL---PLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK---PPAQQPG 320

Query: 2087 GKWALAGPGSPSAGEHG--PGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSC 2144
             + +  GP  P A   G    L   P  + PP   P                  ++ P+ 
Sbjct: 321  HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP----------------GTTKPPAQ 364

Query: 2145 SPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQA 2204
              GPA P +                   +   S  P   Q   +A      +G     Q 
Sbjct: 365  PLGPAKPPA-------------------QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP 405

Query: 2205 RPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTL 2264
             P   PT   G                T    AQ+ G  SP ++   + +PV +     +
Sbjct: 406  GPAKPPTQQVG----------------TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449

Query: 2265 SSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTH-SPCTPPDTLP---RPPQG 2320
             ++  G   P +      GP +PP   P     PA+P P    P  PP   P   +PP  
Sbjct: 450  PAQQAG---PGKTSAQQTGPTKPPSQLP----GPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502

Query: 2321 RRAAQSWSPRLESPRAPTNPEPSAT-PPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQ 2379
            +  +    P+   P  P+  +P +T PP  +  S    A+ SA+ P+  +       + Q
Sbjct: 503  QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS----AKPSAQQPSPAK------PSAQ 552

Query: 2380 DSPKP---SGSGEPRAHPH-QPEDRVPPN 2404
             S KP   +GSG+P   P   P  + PP+
Sbjct: 553  QSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 178/861 (20%), Positives = 293/861 (34%), Gaps = 120/861 (13%)

Query: 803  TSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTE 862
            TS+  KS    Q +  + +  P  Q  S  P P         P LV+QP +        +
Sbjct: 669  TSAVSKSSPQPQQTSPKKDAAP-KQDLSKAPEP------KKPPPLVKQPTLHGSPSAKAK 721

Query: 863  EPDRPDTEPEP-PPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESS 921
            +P   D+  +P PPKEP    E       Q  A +  +K P + K ++      SS  ++
Sbjct: 722  QPPEADSLSKPAPPKEPSVPSE-------QDKAPVADDK-PKQPKMVKPTTDLVSSSSAT 773

Query: 922  FESSVPLSRSPSQ---ESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTV 978
             +  +P S+  SQ   ++   L   S   S      G+  +P  S  +      + +++ 
Sbjct: 774  TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISH 833

Query: 979  P---SHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGP------SAPAPV 1029
            P   S     +++     ++ P  + +    +  +K    GS +  GP      + P P 
Sbjct: 834  PGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQ 893

Query: 1030 APPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQIS 1089
              P    P E+ + F +   S++  P+S+    P   QE+   +      S  S  S + 
Sbjct: 894  QSP---KPQEQSRRFSLNLGSITDAPKSQ----PTTPQETVTGKLFGFGASIFSQASNLI 946

Query: 1090 SAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPP-PVSLFSF 1148
            S A    GP    GPG          P  +A      P +Q P       PP P      
Sbjct: 947  STA-GQPGPHSQSGPG---------APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996

Query: 1149 QHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPL---PPSLFQAPPLPLQPTVLH--PGQL 1203
            +   +    +  E  + QA +   +     PP      SL   P   + PT L   P   
Sbjct: 997  KKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056

Query: 1204 HLPQLMPHPANIPFRQPPSFLPM--------------PYPTSSALSSGFFLPLQSQFAL- 1248
                L     NI  + PP+F                 P P  + +     L  Q+Q A+ 
Sbjct: 1057 STCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116

Query: 1249 -QLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSD-IRLPP---VAPPASSSAPTSAP 1303
             QL GD+    P      AP    ++ +   TE SS    +PP   +         T A 
Sbjct: 1117 GQL-GDIRKMPP------APSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAE 1169

Query: 1304 PLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQI------------LVTQSQGSSA 1351
             + L    +T+    +P  V T+     S +    +              L+ + +   +
Sbjct: 1170 KVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRS 1229

Query: 1352 TVALPKFEEP----------PSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVT 1401
                P  EE           P   T+      H++      ++EE+      P       
Sbjct: 1230 EEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGK 1289

Query: 1402 LPERKGTSLSSESILSL--EGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKAD 1459
             P+ K   L S +  SL  E   +T    ++   P  +    +E  ++K  KE++ S   
Sbjct: 1290 QPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTS 1349

Query: 1460 EKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQ--GRRELEMLSSLSSD-------PSDTK 1510
               +   P    L+ T        S LG         E ++L  L  D       PS   
Sbjct: 1350 SSQQPKSPQG--LSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPS 1407

Query: 1511 EIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSS 1570
            ++  L    LS   A  S    E  +   +PH        V  E  K+Q    SL+    
Sbjct: 1408 DLAKLESTVLSILEAQASTLADEKSEKKTQPH-------EVSPEQPKDQEKTQSLSETLE 1460

Query: 1571 LPLSETSSRPAKSQEGTDSKK 1591
            + +SE   + ++ +     KK
Sbjct: 1461 ITISEEEIKESQEERKDTFKK 1481



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 180/827 (21%), Positives = 265/827 (32%), Gaps = 129/827 (15%)

Query: 673  KPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFES 732
            KPI   T T       Q +H             T +   +R    + SL    +PP  + 
Sbjct: 256  KPIQGPTQTP------QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309

Query: 733  TKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKP------------ 780
            T      PG   A +    +S   PA+P      L  P   QP T KP            
Sbjct: 310  T------PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363

Query: 781  -----------GSGSESGKERRTTSKEISVIQHT--SSFEKSDSLEQPSGLEGEDKPLAQ 827
                        +GSE     +   K ++       +  ++    + P+   G  KPLAQ
Sbjct: 364  QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423

Query: 828  FP---SPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEP-------EPPPKE 877
             P   SP  AP        QP   + P  Q      + +   P   P       +PPP++
Sbjct: 424  QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQ 483

Query: 878  PEKTE-EFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPS--Q 934
            P   +   Q P  ++  +Q P    PP ++        Q  G +   S  P S  PS  Q
Sbjct: 484  PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543

Query: 935  ESNVSLSGSSRSASFERDDHGKAEAP---SPSSDMRPK--------PLGTHMLTVPSHHP 983
             S    S    +    +   GK   P   SPS+   P         PL  +   +  H P
Sbjct: 544  PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPL-CNTTELLLHVP 602

Query: 984  HAREMRRSASEQSP-----NVSHSAHMTETRSKSFDYGSL--SLTGPSAPAPVAP-PARV 1035
                       Q+        + + H+TE +        +  +L G  AP P +P P   
Sbjct: 603  EKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLK 662

Query: 1036 APPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSH 1095
              P      + + +   +    + + APK +  S+ P+P    P  K      S +A + 
Sbjct: 663  TAPVTTTSAVSKSSPQPQQTSPKKDAAPK-QDLSKAPEPKKPPPLVKQPTLHGSPSAKAK 721

Query: 1096 GGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLV--- 1152
              PP      +  PP  P+VP  +       PVA     +   + P   L S        
Sbjct: 722  -QPPEADSLSKPAPPKEPSVPSEQD----KAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776

Query: 1153 ---------QHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPT--VLHP- 1200
                     Q E   +P   +  A  S  S P +   + P   +A P P   +  + HP 
Sbjct: 777  DIPSSKVQSQAEEKTTPPLKTDSAKPS-QSFPPTGEKVSPFDSKAIPRPASDSKIISHPG 835

Query: 1201 ------GQLHLPQLM----PHPANIPFRQPPSFLPM----PYPTSSALSSGFFLPLQSQ- 1245
                  GQ  +  +     P  A       P   PM    P P     ++G  +P   Q 
Sbjct: 836  PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQS 895

Query: 1246 ---------FALQLPGDVESHLPQIKTSLAPLATGSA---GLSPSTEYSSDIRLPPVAPP 1293
                     F+L L G +        T+     TG     G S  ++ S+ I       P
Sbjct: 896  PKPQEQSRRFSLNL-GSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGP 954

Query: 1294 ASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATV 1353
             S S P  AP    PA          P   Q    S G A       I V +   + A  
Sbjct: 955  HSQSGP-GAPMKQAPAPSQ-------PPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAE 1006

Query: 1354 AL-PKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVP 1399
             L PK E+ P+   T        +    S  +E Q    PT   + P
Sbjct: 1007 KLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053



 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 136/588 (23%), Positives = 201/588 (34%), Gaps = 103/588 (17%)

Query: 1865 EDEEESQDELSRPSSEAPPPGPPHALRAD---SSPILGPQPPDAPASGTEATRGSSVSEA 1921
            E  + S    S+P  + P PG P A +     S P  GP  P A  SG            
Sbjct: 292  ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP--GPAKPPAQPSGLTKPLAQQPGTV 349

Query: 1922 ERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPL 1981
            +              PG       PLG  +       S KP S +    P  +A ++PP 
Sbjct: 350  K---------PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ----PGPKALAQPPG 396

Query: 1982 ARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPL 2041
              K       +  Q+  PA+ P     +P  L   PG      P  +P    +P+     
Sbjct: 397  VGK-------TPAQQPGPAKPPTQQVGTPKPLAQQPGLQS---PAKAPGPTKTPVQQPGP 446

Query: 2042 GRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGE 2101
            G+  A +A         T P  P   P++   PG A+ PP+   P K     PGS     
Sbjct: 447  GKIPAQQAGPGKTSAQQTGPTKP---PSQL--PGPAKPPPQQPGPAKPPPQQPGSAKPPS 501

Query: 2102 HGPGLGLDPRVLFPPAPLPHKLLSRSPETCASP-WKAESRSPSC-SPGPAHP---LSSRP 2156
              PG    P    P  P P K   + P +   P  +  S  PS   P PA P    S++P
Sbjct: 502  QQPGSTKPP----PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557

Query: 2157 FSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQM-VQARPGAHPTLLPG 2215
             S      G  L     +  +  P  SQ L +  CPL     + + V  +   +      
Sbjct: 558  VSQTGS--GKPLQPPTVSPSAKQP-PSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQ 614

Query: 2216 PTAAWVSGFSGGGSDLTGARE-----AQER----GRWSPTESSS---------ASVSPVA 2257
             T   + GF+     LT  +E      Q +    G  +P  SS           + S V+
Sbjct: 615  TTVCSLCGFN-PNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVS 673

Query: 2258 KVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGT--GAP-------------AEPT 2302
            K S     +  +    PK+       P +PP      T  G+P             ++P 
Sbjct: 674  KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733

Query: 2303 PTHSPCTP--------PDTLPRPPQGRR--------AAQSWSPRLESPRAPTNPEPSATP 2346
            P   P  P         D  P+ P+  +        ++ +  P + S +  +  E   TP
Sbjct: 734  PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793

Query: 2347 PLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHP 2394
            PL   S     A+ S  FP     +S  P   +  P+P+   +  +HP
Sbjct: 794  PLKTDS-----AKPSQSFPPTGEKVS--PFDSKAIPRPASDSKIISHP 834



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 245/1192 (20%), Positives = 368/1192 (30%), Gaps = 262/1192 (21%)

Query: 30   SVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEAS 89
            SV  S+P P        + P Q     QP PG     + G +    + Q  P +PP + S
Sbjct: 293  SVKPSLPSPS-------KPPIQ-----QPTPGKPPAQQPGHE----KSQPGPAKPPAQPS 336

Query: 90   VHISQLPQHPLT-------------PAF-MSPGKPEHLLEGSTWQLVDPMRPGPSGSFVA 135
                 L Q P T             PA  + P KP     GS  +     +PGP      
Sbjct: 337  GLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGS--EKPSSEQPGPKALAQP 394

Query: 136  PGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQ 195
            PG+       P  A   PP    G PK    +P   S        K   +   PGK   Q
Sbjct: 395  PGVGKTPAQQPGPAK--PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452

Query: 196  YCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMG 255
                   K S  Q        + P P  P              +        A   S   
Sbjct: 453  QAGP--GKTSAQQTGPTKPPSQLPGPAKP------PPQQPGPAKPPPQQPGSAKPPSQQP 504

Query: 256  GEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGLYSSG 315
            G   P   +    PG     P +  S      T   S  P    P  +QP       S  
Sbjct: 505  GSTKPPPQQ----PGPAKPSPQQPGS------TKPPSQQPGSAKPSAQQP-------SPA 547

Query: 316  SHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSH-KPEDTHTIKQKLALRLSERKKV 374
              S+      +SQ+ + + L+  PP V PS++ P S   P+    +     L L      
Sbjct: 548  KPSAQQSTKPVSQTGSGKPLQ--PPTVSPSAKQPPSQGLPKTICPLCNTTELLLH----- 600

Query: 375  IDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTA 434
            + E+A  +  ++  T     +         +P  T  K +  +       +G   A +  
Sbjct: 601  VPEKANFNTCTECQT-----TVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPV-P 654

Query: 435  TSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRR 494
            +S QP L  +     S V  S P+ Q                 TS      P++  LS+ 
Sbjct: 655  SSPQPKLKTAPVTTTSAVSKSSPQPQ----------------QTSPKKDAAPKQ-DLSKA 697

Query: 495  SSMESPKSSLYREPL--SSHSEKTK--PEQSLLSLQHPPSTAPPVP-------------- 536
               + P   L ++P    S S K K  PE   LS   PP   P VP              
Sbjct: 698  PEPKKP-PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK-EPSVPSEQDKAPVADDKPK 755

Query: 537  ----LLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKR--- 589
                +  +  + S++   + P  P     S  +  T     + S+    S P   ++   
Sbjct: 756  QPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP 815

Query: 590  --QPAIELPLGGEYSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNI 647
                AI  P         PGPSS+    K  D V+ KE     +TK   K          
Sbjct: 816  FDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD-------- 867

Query: 648  CGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTL 707
                                    AKP+  G+ T P    +  +  P  Q          
Sbjct: 868  ------------------------AKPMPKGSPTPPGPRPTAGQTVPTPQQS-------- 895

Query: 708  ELTPLRKRRKEKSLGDEEEPPAFESTKSQ---------FGSPGPSDAARNLPLESTKSP- 757
                 + RR   +LG   + P  + T  Q         FG+   S A+  +       P 
Sbjct: 896  PKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPH 955

Query: 758  AEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSG 817
            ++     P  + P   QP T + G    +G+     +K I V + T +   ++ LE  + 
Sbjct: 956  SQSGPGAPMKQAPAPSQPPTSQ-GPPKSTGQAPPAPAKSIPVKKETKA-PAAEKLEPKAE 1013

Query: 818  LEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEP------ 871
                 K       PPP    +S       L  +P   V    + + P    T P      
Sbjct: 1014 QAPTVKRTETEKKPPPIKDSKS-------LTAEPQKAVLPTKLEKSPKPESTCPLCKTEL 1066

Query: 872  ----EPPPK-------------------EPEKTEEFQW------PQRSQTLAQLPAEKLP 902
                + PP                     P  TE  +W       QR+ +       K+P
Sbjct: 1067 NIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP 1126

Query: 903  PKKKRLRLAEMAQSSGESSFESSVP----LSRSPSQE-----SNVSLSGSSRSASFE--- 950
            P     + + M   +  SS +++VP    L +   QE       V L     + S E   
Sbjct: 1127 PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIP 1186

Query: 951  -------RDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSA 1003
                   + +  K E    S+    KPL      +P       E +  + E+ P +    
Sbjct: 1187 PMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIP------EEEKIRSEEKKPLLEEKK 1240

Query: 1004 HMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAP 1063
               E +                   + P A+ + PE +K  L++        + E  VAP
Sbjct: 1241 PTPEDKK------------------LLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAP 1282

Query: 1064 KGRQESEEPQ------PSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRP 1109
            K  QE ++PQ      PS +  S      + +        PP    P Q  P
Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP 1334



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 204/1046 (19%), Positives = 347/1046 (33%), Gaps = 163/1046 (15%)

Query: 26   AIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPP 85
            A Q  + S    PG      Q+    ++ A Q  PG +S  + G  +   Q   P K PP
Sbjct: 422  AQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP 481

Query: 86   IEASVHISQLPQHPLTPAFMSPG--KPEHLLEGSTWQLVDPMRPGPS-------GSFVAP 136
             +           P  P    PG  KP     GST     P +PGP+       GS   P
Sbjct: 482  QQPG---------PAKPPPQQPGSAKPPSQQPGST--KPPPQQPGPAKPSPQQPGSTKPP 530

Query: 137  GLHP----QSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKY 192
               P     S   PS A     +    V +    +P Q    PT     K+   Q   K 
Sbjct: 531  SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ---PPTVSPSAKQPPSQGLPKT 587

Query: 193  ICQYCSRPCAKPSVLQK-HIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLA 251
            IC  C+       V +K +  + T  +   C  CGF+     N +         +   + 
Sbjct: 588  ICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN----PNPHLTEVKEWLCLNCQMK 643

Query: 252  SGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGL 311
              +GG++ P       +P      P     T     TSA S    + SP+P+Q       
Sbjct: 644  RALGGDLAP-------VP----SSPQPKLKTAPVTTTSAVS----KSSPQPQQT------ 682

Query: 312  YSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEH----PLSHKPEDTHTI------K 361
                  S   +       S A   + PPP V+  + H      + +P +  ++      K
Sbjct: 683  ------SPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK 736

Query: 362  QKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGK 421
            +       ++  V D++       K +T+      S SA  +   P++  +S AE     
Sbjct: 737  EPSVPSEQDKAPVADDKPKQPKMVKPTTD---LVSSSSATTKPDIPSSKVQSQAE----- 788

Query: 422  CGRIGQRTAMLTATSTQP--LLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTS 479
                 + T  L   S +P    P + E        ++PR      I      +       
Sbjct: 789  ----EKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844

Query: 480  EIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLR 539
            ++D V+ +      ++ M SPK      P  S +       +  ++  P  +  P    R
Sbjct: 845  QVDPVQKKEEPKKAQTKM-SPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSR 903

Query: 540  SHSMPSAACT------ISTPHHPFRGS-YSFDDHITD------SEALSHSSHVFTSHPRM 586
              S+   + T       +TP     G  + F   I        S A     H  +     
Sbjct: 904  RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963

Query: 587  LKRQPAIELPLGGEYSSEEPG----------PSSKDTASKPSDEVEP--------KESEL 628
            +K+ PA   P   +   +  G          P  K+T +  ++++EP        K +E 
Sbjct: 964  MKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTET 1023

Query: 629  TKKTKKGLKTKGVIYECN--ICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAE 686
             KK      +K +  E    +   + +K    E+      +EL I        +T  E +
Sbjct: 1024 EKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECK 1083

Query: 687  KSQIEHEPWSQMMHY-KLGTTLELTPLRKRRKEKSLGDEEEPPAFESTKSQFGSPGPSDA 745
                    ++   H  ++   L L    +R     LGD  + P   S       P P+++
Sbjct: 1084 NQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTES 1143

Query: 746  A----------RNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSK 795
            +          + +  +  +   E  K +      T    + P   +  +  +E +    
Sbjct: 1144 SSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKD 1203

Query: 796  EISVIQHTSSFEKSDSL--EQPSGLEGEDKPLAQFPSPPP-----APHGR-SAHSLQPKL 847
            + S +Q      +   L  E+      E KPL +   P P      P  + SA   Q   
Sbjct: 1204 KASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD 1263

Query: 848  VRQPNIQVPEILV--------TEEPDRPDTE--------PEPPPKEPEKTEEFQWPQRSQ 891
            + +  +Q+ E  +         +E  +P T+        P+  PKE +KT +    Q   
Sbjct: 1264 LLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQP 1323

Query: 892  TLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLS-GSSRS---- 946
                 P +  P K+K  +  + + +S     +S   LS +      +S S G   S    
Sbjct: 1324 PCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPT 1383

Query: 947  ------ASFERDDHGKAEAPSPSSDM 966
                     ++D   +  +PS  SD+
Sbjct: 1384 DEKDILKGLKKDSFSQESSPSSPSDL 1409



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 142/626 (22%), Positives = 218/626 (34%), Gaps = 132/626 (21%)

Query: 1873 ELSRPSSEAPPPG---PPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSC 1929
            ++  P   A  PG   P  A     +P+  P P   PA   +A  G + ++    T    
Sbjct: 414  QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ--QAGPGKTSAQQTGPTKPPS 471

Query: 1930 SMSSQSMPGLPWLGPAPL-----GSVEKDTGSALSYKPV---------SPRRPWS---PS 1972
             +   + P     GPA       GS +  +    S KP          SP++P S   PS
Sbjct: 472  QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531

Query: 1973 KEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQ 2032
            ++ GS  P A++ S  K  S+ Q   P  +  +  P  P   V P           P  Q
Sbjct: 532  QQPGSAKPSAQQPSPAK-PSAQQSTKPVSQTGSGKPLQPPT-VSPS-------AKQPPSQ 582

Query: 2033 LSPLTLCPLGRELAPRAHVLSKLEGTT--------------DPGLPRYSPTRRWSPGQAE 2078
              P T+CPL        HV  K    T              +P  P  +  + W     +
Sbjct: 583  GLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPN-PHLTEVKEWLCLNCQ 641

Query: 2079 SPPRSAPPGKWALAGPGSPSAGEHGPGLGLDP----RVLFPPAPLPHKLLSRSPETCASP 2134
                     K AL G  +P      P L   P      +   +P P +    SP+  A+P
Sbjct: 642  M--------KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQT---SPKKDAAP 690

Query: 2135 WKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLI 2194
             +  S++P     P  PL  +P       HG   A+ ++      P  +  L++   P  
Sbjct: 691  KQDLSKAPEPKKPP--PLVKQP-----TLHGSPSAKAKQ------PPEADSLSKPAPPKE 737

Query: 2195 PIGGIQMVQARPGAHPTLLPG---PTAAWVSGFSGGGS-DLTGAR-EAQERGRWSP---T 2246
            P    +  +A         P    PT   VS  S     D+  ++ ++Q   + +P   T
Sbjct: 738  PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKT 797

Query: 2247 ESSSASVS--PVA-KVSKFTL------------------SSELEGGDY-----PKERERT 2280
            +S+  S S  P   KVS F                    SSE +G         KE  + 
Sbjct: 798  DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857

Query: 2281 GGGPGRP-PDWTPHGTGAPAE--PTPTHSPCTP-PDTLPRP-PQGRRAAQSWSPRLESPR 2335
                  P PD  P   G+P    P PT     P P   P+P  Q RR + +     ++P+
Sbjct: 858  AQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK 917

Query: 2336 A-PTNPEPSATPPL---------------DRSSSVGCLAEASARFPARTRNLSGEPRTRQ 2379
            + PT P+ + T  L                 +   G  +++    P +      +P T Q
Sbjct: 918  SQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQ 977

Query: 2380 DSPKPSGSGEP---RAHPHQPEDRVP 2402
              PK +G   P   ++ P + E + P
Sbjct: 978  GPPKSTGQAPPAPAKSIPVKKETKAP 1003



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 155/751 (20%), Positives = 250/751 (33%), Gaps = 117/751 (15%)

Query: 228  SFKTKSNLYKHRKSHAHRIKAGLASGMGGEMYPH-----GLEMERIPGEEFEEPTEGEST 282
            + K+   +Y+      H+ KA  A+    E++       G+ +E    E   E T   S 
Sbjct: 1910 ALKSAEEMYEEMMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSV 1969

Query: 283  DSEEETSATSGHP-AELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPF 341
            D    T     +   +   R ++  LS  +Y       +  +    +  +  S+      
Sbjct: 1970 DGSLLTRQEEENGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDI 2029

Query: 342  VEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAE 401
            V  S   P SH+  D  T    +     E +K++D  A             Y    +  +
Sbjct: 2030 VSSSFIIPESHEIVDLGT----MVTSTEEERKLLDADA------------AYEELMKRQQ 2073

Query: 402  QQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQV 461
             Q++P ++  ++       +      R    + TS+  L   S  D  S   LS+P  ++
Sbjct: 2074 MQLTPGSSPTQAPIGEDMTESTMDFDRMPDASLTSSV-LSGASLTDSTSSATLSIPDVKI 2132

Query: 462  IEHITKLITINEAVVD-TSEIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQ 520
             +H +     +E V D T EI  +    S +             Y EP  S S  + P  
Sbjct: 2133 TQHFSTEEIEDEYVTDYTREIQEIIAHESLILT-----------YSEP--SESATSVPPS 2179

Query: 521  SLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHV- 579
                    PS    V  + +    S   T+ +    +           DSE +S S++  
Sbjct: 2180 DT------PSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFP 2233

Query: 580  --FTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDTASKPSDEVEPK------------- 624
                 +P  +        P  G  S++    S  D AS   + V PK             
Sbjct: 2234 GSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDL 2293

Query: 625  ---ESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHT 681
               E +  KK KK     G+I E       Y+ +   EA +                  T
Sbjct: 2294 LISEKDPVKKAKKETGN-GIILEVL---EAYRDKKELEAER------------------T 2331

Query: 682  SPEAEKSQIEHEPWSQM---MHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFESTKSQFG 738
                 ++  +H P S +   M  +L TT   T      +EK     + P    S  S   
Sbjct: 2332 KSSLSETVFDHPPSSVIALPMKEQLSTTY-FTSGETFGQEKPAS--QLPSGSPSVSSLPA 2388

Query: 739  SPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEIS 798
             P P   + +L + +   P  P    P    P    P  P P S   +   ++  +    
Sbjct: 2389 KPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASP 2448

Query: 799  VIQHTSSFEKSDSLEQPSGLEGEDKPLAQF--PSPPPAPHGRSAHSLQPKLVRQPNIQVP 856
            V   T  F+   +LE  + L     P+ +    +PPP P         PK    P+    
Sbjct: 2449 VTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVP---------PK----PSSIPS 2495

Query: 857  EILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQS 916
             ++ T  P     EP  PP  P+       PQ   T  Q P + + PK   L L      
Sbjct: 2496 GLVFTHRP-----EPSKPPIAPKPV----IPQ-LPTTTQKPTD-IHPKPTGLSLTSSMTL 2544

Query: 917  SGESSFESSVPLSRSP-SQESNVSLSGSSRS 946
            +  +S +  +P   SP S  SN S    S+S
Sbjct: 2545 NLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 117/557 (21%), Positives = 188/557 (33%), Gaps = 75/557 (13%)

Query: 1181 LPPSLFQAPPLPLQPTVLHPGQLHLPQ-------LMPHPANIPFRQPPSFLPMPYPTSSA 1233
            + P L Q PP P+ P    PG+  L Q           P  I  + P +  P+  PT + 
Sbjct: 207  IKPPLQQQPPKPI-PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTP 265

Query: 1234 LSSGFFLPLQ--------SQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDI 1285
             +    LPLQ         Q  +     V+  LP    S  P+   + G  P+ +   + 
Sbjct: 266  QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS--PSKPPIQQPTPGKPPAQQPGHEK 323

Query: 1286 RLP-PVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVT 1344
              P P  PPA  S  T   PLA    P T+   V P    T  P+         +Q   T
Sbjct: 324  SQPGPAKPPAQPSGLTK--PLAQQ--PGTVKPPVQPPGT-TKPPAQPLGPAKPPAQ--QT 376

Query: 1345 QSQGSSATVALPK-FEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLP 1403
             S+  S+    PK   +PP  G T          PGP+          PT  +  P  L 
Sbjct: 377  GSEKPSSEQPGPKALAQPPGVGKTPAQQ------PGPAKP--------PTQQVGTPKPLA 422

Query: 1404 ERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLE 1463
            ++ G          L+  +   G +K  +   G  ++  +     +   ++        +
Sbjct: 423  QQPG----------LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472

Query: 1464 LVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALSHG 1523
            L  P            +P     G      ++       S  P  TK  P  P PA    
Sbjct: 473  LPGPA-----------KPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP 521

Query: 1524 TAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSSLPLSETSSRPAKS 1583
              PGS         S KP  +  +P     + S +Q   P     S  PL   +  P+  
Sbjct: 522  QQPGSTKPPSQQPGSAKPSAQQPSP----AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAK 577

Query: 1584 QEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVS 1643
            Q  +        P  +TT       L+  +  +        +     C    NP+L  V 
Sbjct: 578  QPPSQGLPKTICPLCNTTE----LLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVK 633

Query: 1644 TKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLA 1703
                L+  + K+ +  +   + ++P P+  +  P ++          P   SP  +KD A
Sbjct: 634  EWLCLN-CQMKRALGGDLAPVPSSPQPKL-KTAPVTTTSAVSKSSPQPQQTSP--KKD-A 688

Query: 1704 RVEKEEERRGEPEEDAP 1720
              +++  +  EP++  P
Sbjct: 689  APKQDLSKAPEPKKPPP 705



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 181/856 (21%), Positives = 289/856 (33%), Gaps = 138/856 (16%)

Query: 1    MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFP 60
            +DP Q  +  KKA+    K   K +A      S  P PG    A Q  P      PQ  P
Sbjct: 846  VDPVQKKEEPKKAQ---TKMSPKPDAKPMPKGSPTP-PGPRPTAGQTVPT-----PQQSP 896

Query: 61   GPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQL---------PQHPLTPAFMSPGKPE 111
             P    R  S         P  +P         +L             L      PG   
Sbjct: 897  KPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHS 956

Query: 112  HLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVP-KVFVPRPSQ 170
                G+      PM+  P     AP   P SQ  P      PP     +P K     P+ 
Sbjct: 957  QSGPGA------PMKQAP-----APSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAA 1005

Query: 171  VSLKP------TEEAHKKERKPQKPGKYICQYCSRP--CAKPSVLQKHIRSHTGERPYPC 222
              L+P      T +  + E+KP  P K      + P     P+ L+K         P P 
Sbjct: 1006 EKLEPKAEQAPTVKRTETEKKPP-PIKDSKSLTAEPQKAVLPTKLEKS--------PKPE 1056

Query: 223  GPCGFSFKTKSNLYKHRKSHAH---RIKAGLASGMGGEMYPHGLEMER--IPGEEFEEPT 277
              C    KT+ N+      + +     K  + +  G    PH  E++       + +   
Sbjct: 1057 STCPLC-KTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAI 1115

Query: 278  EGESTDSEEETSATSGHPAELSPRPKQ---------PLLSSGLYSSGSHSSSHERCSLSQ 328
             G+  D  +   A SG  A   P P +         P +           +  E+  L +
Sbjct: 1116 SGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEK 1175

Query: 329  SSTAQSLEDPPPFV-----------EPSSEHPLSHK---PEDTHTIKQKLALRLSERKKV 374
                 S+E  PP V           E      L  K   PE+   I ++  +R  E+K +
Sbjct: 1176 VKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPL 1235

Query: 375  IDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKC-GRIGQRTAMLT 433
            ++E+       K   E    +++ + E+Q    +   KS  +I   K  GR+  +T    
Sbjct: 1236 LEEKKPTPEDKKLLPE----AKTSAPEEQ---KHDLLKSQVQIAEEKLEGRVAPKTVQ-- 1286

Query: 434  ATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSR 493
                QP   +  E  PS  P S+P+    +  TK I        T++ D V+P +     
Sbjct: 1287 -EGKQPQTKM--EGLPSGTPQSLPKED--DKTTKTIKEQPQPPCTAKPDQVEPGK----E 1337

Query: 494  RSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTP 553
            ++  E  KS       +S S++ K  Q L    +            S S+      I T 
Sbjct: 1338 KTEKEDDKSD------TSSSQQPKSPQGLSDTGYSSDGI-------SSSLGEIPSLIPTD 1384

Query: 554  HHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDT 613
                      D    +S   S S         + K +  +   L  + S+     S K T
Sbjct: 1385 EKDILKGLKKDSFSQESSPSSPSD--------LAKLESTVLSILEAQASTLADEKSEKKT 1436

Query: 614  ASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAK 673
                    +PK+ E T+   + L+    I E  I  ++ +++D +   KK    ++  +K
Sbjct: 1437 QPHEVSPEQPKDQEKTQSLSETLEI--TISEEEIKESQEERKDTF---KKDSQQDIPSSK 1491

Query: 674  PISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFEST 733
                    S   +      EP+  +   +  +  E +P+ +R++  S+G       ++  
Sbjct: 1492 D---HKEKSEFVDDITTRREPYDSV---EESSESENSPVPQRKRRTSVGSSSS-DEYKQE 1544

Query: 734  KSQFGSPGPSDAARNLPLE-STKSPAEPSK-------SVPSLEGPTGFQPRTPKPGSGS- 784
             SQ GS    D  R   +E S    A  S+        +  +   T  Q +    G G  
Sbjct: 1545 DSQ-GSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKI 1603

Query: 785  ESGKERRTTSKEISVI 800
             +GK RR T K  + I
Sbjct: 1604 TAGKHRRLTRKSSTSI 1619



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 57/223 (25%), Positives = 82/223 (36%), Gaps = 29/223 (13%)

Query: 1217 FRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLS 1276
            F  PPS + +  P    LS+ +F   ++ F  + P    S LP    S++ L        
Sbjct: 2340 FDHPPSSV-IALPMKEQLSTTYFTSGET-FGQEKPA---SQLPSGSPSVSSLPAKPRPFF 2394

Query: 1277 PSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDT--------MVSLVVPVRVQTNMP 1328
             S+      + PP  PP     P   PP   P  P T           L V   V T  P
Sbjct: 2395 RSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454

Query: 1329 SYGSAMYTTLSQILVTQSQGSSATVALPKFEEP-PSKGTTVCGADVHEVGPGPSGLSEEQ 1387
             + +   TTL    V +S G   T        P P K +++    V    P PS     +
Sbjct: 2455 LFDAV--TTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPS-----K 2507

Query: 1388 SRAFPTPYL-RVPVTL-------PERKGTSLSSESILSLEGSS 1422
                P P + ++P T        P+  G SL+S   L+L  S+
Sbjct: 2508 PPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSA 2550



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 86/360 (23%), Positives = 129/360 (35%), Gaps = 83/360 (23%)

Query: 1107 DRPPLGP-TVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFST 1165
            D PP     +P  E L   +    +T   EKP    P    S   L    P +   FF +
Sbjct: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSL----PAKPRPFFRS 2396

Query: 1166 QAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLP 1225
             ++  + + P   PP PP     PP P  P                        PP   P
Sbjct: 2397 SSLD-ISAQPPPPPPPPP-----PPPPPPP------------------------PPPPPP 2426

Query: 1226 MPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDI 1285
            +P PTS   +    LP + +  +  P    + L    T+L   A   +   P T   +  
Sbjct: 2427 LPPPTSPKPT---ILP-KKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT-- 2480

Query: 1286 RLPPVAPPASSSAPT----------SAPPLA-LPACPDTMVSLVVPVRVQTNMPSYGSAM 1334
              PP  PP  SS P+          S PP+A  P  P    +   P  +       G ++
Sbjct: 2481 TAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPK--PTGLSL 2538

Query: 1335 YTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTP 1394
             ++++  LVT     SA   LP    P              + P  +  S   S++    
Sbjct: 2539 TSSMTLNLVT-----SADYKLPSPTSP--------------LSPHSNKSSPRFSKSLTET 2579

Query: 1395 YLRVPVTLPERKGT---SLSSESILSLE-GSSSTAGGSKR----VLSPAGSLELTMETQQ 1446
            Y  V +TLP   GT   S +S++I S   GS S    S      V+ P  ++E+ + ++Q
Sbjct: 2580 Y--VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQ 2637



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 46/161 (28%), Positives = 60/161 (37%), Gaps = 26/161 (16%)

Query: 2245 PTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPT 2304
            P+ S S S  P AK   F  SS L+    P         P  PP   P     P  P P 
Sbjct: 2377 PSGSPSVSSLP-AKPRPFFRSSSLDISAQPP--------PPPPPPPPP-----PPPPPPP 2422

Query: 2305 HSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARF 2364
              P  PP T P+P        +  P+ +   A  +P  +ATP  D  +++   A   +  
Sbjct: 2423 PPPPLPPPTSPKP--------TILPKKKLTVA--SPVTTATPLFDAVTTLETTAVLRSNG 2472

Query: 2365 PARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPPNA 2405
               TR  +  P      PKPS         H+PE   PP A
Sbjct: 2473 LPVTRICTTAP--PPVPPKPSSIPSGLVFTHRPEPSKPPIA 2511



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 38/172 (22%), Positives = 64/172 (37%), Gaps = 19/172 (11%)

Query: 1860 DEDEDEDEEESQDELSRPSSEAPPP----GPPHALRADSSPILGPQPPDAP----ASGTE 1911
            + D D    +     S P  +  P     G    LRADS+  L P PP +P    +  + 
Sbjct: 3570 EADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISP 3629

Query: 1912 ATRGSSVSEA----ERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRR 1967
             + G ++  A    E+      S      P +  + PA          + +  + +S  +
Sbjct: 3630 LSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPA------SPKTAKMMQRSMSDPK 3683

Query: 1968 PWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPA-REPQASAPSPPGLHVDPG 2018
            P SP+ +  SR P       T   S     S A ++ + + P+PP   +  G
Sbjct: 3684 PLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTG 3735



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 35/172 (20%), Positives = 56/172 (32%), Gaps = 14/172 (8%)

Query: 1877 PSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSM 1936
            P    PPP PP  L   +SP     P       +  T  + + +A     ++  + S  +
Sbjct: 2414 PPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGL 2473

Query: 1937 PGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQR 1996
            P       AP               PV P+    PS    +  P   K  +      PQ 
Sbjct: 2474 PVTRICTTAP--------------PPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQL 2519

Query: 1997 CSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPR 2048
             +  ++P    P P GL +     +  +     +L      L P   + +PR
Sbjct: 2520 PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPR 2571



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 65/285 (22%), Positives = 99/285 (34%), Gaps = 50/285 (17%)

Query: 1329 SYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQS 1388
            S  S   TT  Q +V + QG    +  P  ++ P K          + GPG   L ++  
Sbjct: 182  SEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIP------KQQGPGRDPLQQD-- 233

Query: 1389 RAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQK 1448
                              GT  S  S    +  S   G  K +  P      T +T   K
Sbjct: 234  ------------------GTPKSISSQQPEKIKSQPPGTGKPIQGPT----QTPQTDHAK 271

Query: 1449 RVKEEEASKADEK-LELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPS 1507
               + +AS+   K  ++V+  SV  +       P K  +     G+   +      S P 
Sbjct: 272  LPLQRDASRPQTKQADIVRGESVKPSLPS----PSKPPIQQPTPGKPPAQQPGHEKSQPG 327

Query: 1508 DTKEIPPLPHPALSHGTAPGSEALKEYPQPSG--KPHRRGLTPL------SVKKEDSKEQ 1559
              K  PP     L+   A     +K   QP G  KP  + L P       +  ++ S EQ
Sbjct: 328  PAK--PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ 385

Query: 1560 PDLPSLAPPSSLPLSETS----SRPAKSQEGTDSKKVLQFPSLHT 1600
            P   +LA P  +  +       ++P   Q GT  K + Q P L +
Sbjct: 386  PGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT-PKPLAQQPGLQS 429


>gi|189217876 sal-like 1 isoform b [Homo sapiens]
          Length = 1227

 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 109/453 (24%), Positives = 166/453 (36%), Gaps = 84/453 (18%)

Query: 38  PGSGTAATQESPAQEL---LAPQ--PFPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHI 92
           P  GT  T  +P   L   L+ Q     G +  L   S   +G +Q PP + P  +S + 
Sbjct: 173 PSQGTLRTSANPLSTLSSHLSQQLAAAAGLAQSLASQSASISGVKQLPPIQLPQSSSGNT 232

Query: 93  -------SQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSG------SFVAPGLH 139
                  S    + L  A  +P   +         + +P     S       S ++P  +
Sbjct: 233 IIPSNSGSSPNMNILAAAVTTPSSEKVASSAGASHVSNPAVSSSSSPAFAISSLLSPASN 292

Query: 140 PQSQLLPSHASI--IPPEDLPGVPKVFVPRPSQVSLKPTEEA--------HKKERKPQKP 189
           P   LLP  AS   + P  LP +        S  +L    ++          K    +  
Sbjct: 293 P---LLPQQASANSVFPSPLPNIGTTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAF 349

Query: 190 GKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAG 249
            K+ C++C++     S LQ H+RSHTGERP+ C  CG  F TK NL  H + H       
Sbjct: 350 FKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK------ 403

Query: 250 LASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSS 309
                  E YPH ++M   P  E             +    ++G P  +S  P++P+   
Sbjct: 404 -------EKYPH-IQMNPYPVPE-----------HLDNIPTSTGIPYGMSIPPEKPVT-- 442

Query: 310 GLYSSGSHSSSHERCSLSQSSTAQSLEDPP------PFV--EPSSEHPLSHK-PEDTHTI 360
                   S    +  L   +T+  L  PP      PF+  E  +  P+SH       ++
Sbjct: 443 --------SWLDTKPVLPTLTTSVGLPLPPTLPSLIPFIKTEEPAPIPISHSATSPPGSV 494

Query: 361 KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFG 420
           K       S  + +      L   ++GST      +SE +    +   T + S       
Sbjct: 495 KSDSGGPESATRNL----GGLPEEAEGSTLPPSGGKSEESGMVTNSVPTASSSVLSSPAA 550

Query: 421 KCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVP 453
            CG  G  T     T T PLLPL +E   +  P
Sbjct: 551 DCGPAGSAT-----TFTNPLLPLMSEQFKAKFP 578



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 43/152 (28%), Positives = 64/152 (42%), Gaps = 15/152 (9%)

Query: 95   LPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRP-GPSGSFVAPGLHPQSQLLPSHAS--- 150
            L QH LT          H +     QL +P    GP+ +      +  S L+ +  +   
Sbjct: 947  LKQHMLT----------HQMRDLPSQLFEPSSNLGPNQNSAVIPANSLSSLIKTEVNGFV 996

Query: 151  IIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKH 210
             + P+D    P   VP    +S   T          + P ++ C  C +  +  S LQ H
Sbjct: 997  HVSPQDSKDTPTSHVPS-GPLSSSATSPVLLPALPRRTPKQHYCNTCGKTFSSSSALQIH 1055

Query: 211  IRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242
             R+HTGE+P+ C  CG +F TK NL  H  +H
Sbjct: 1056 ERTHTGEKPFACTICGRAFTTKGNLKVHMGTH 1087



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 64/255 (25%), Positives = 98/255 (38%), Gaps = 20/255 (7%)

Query: 1767 SMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM---KSKAHSKKCQETGVLEELEAEE 1823
            S LK H RTHT  RP+ CK C  AF TKGNL  H    ++    +      + ++     
Sbjct: 622  SALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNA 681

Query: 1824 GTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPP 1883
                   +   G +         +S+  +SD+ S  DE   +D +   DE      E   
Sbjct: 682  VVLQQHIRMHMGGQIPNTPVPDSYSESMESDTGS-FDEKNFDDLDNFSDENMEDCPEGSI 740

Query: 1884 PGPPHALRA-----DSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPG 1938
            P  P +  A      SSP+  P    + A+     +  +   AE+L AS  S+ + S+ G
Sbjct: 741  PDTPKSADASQDSLSSSPL--PLEMSSIAALENQMKMINAGLAEQLQASLKSVENGSIEG 798

Query: 1939 --LPWLGPAPLGSVE-KDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQ 1995
              L     +  G +E +  GS    +  S  +  SPS            H     +  PQ
Sbjct: 799  DVLTNDSSSVGGDMESQSAGSPAISESTSSMQALSPSNST------QEFHKSPSIEEKPQ 852

Query: 1996 RCSPAREPQASAPSP 2010
            R  P+      +P+P
Sbjct: 853  RAVPSEFANGLSPTP 867



 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 27/66 (40%), Positives = 33/66 (50%), Gaps = 5/66 (7%)

Query: 177 EEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLY 236
           E   KK   P +     C  C R  +  S L+ H R+HTGERP+ C  CG +F TK NL 
Sbjct: 599 ENIDKKATDPNE-----CIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLK 653

Query: 237 KHRKSH 242
            H   H
Sbjct: 654 THYSVH 659



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 3/56 (5%)

Query: 1749 RGRGKY---VCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM 1801
            R RGK+    C+ CG      S L  H R+HT  RP++C  C+  F TKGNL +HM
Sbjct: 896  RDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHM 951



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 23/52 (44%), Positives = 27/52 (51%)

Query: 194 CQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHR 245
           C  C +  A  S L  H RSHT ERP+ C  C   F TK NL +H  +H  R
Sbjct: 906 CDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHMLTHQMR 957



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 22/49 (44%), Positives = 27/49 (55%)

Query: 1753 KYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM 1801
            ++ C  CG      S L+ H RTHT  +P+ C  C  AF TKGNL  HM
Sbjct: 1036 QHYCNTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHM 1084



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 64/263 (24%), Positives = 101/263 (38%), Gaps = 39/263 (14%)

Query: 1556 SKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLH---TTTNVSWCYLNYI 1612
            + +  DLP+ + PS   L  TS+ P  +     S+++     L     + + S   +  +
Sbjct: 161  ASQNADLPTSSSPSQGTL-RTSANPLSTLSSHLSQQLAAAAGLAQSLASQSASISGVKQL 219

Query: 1613 KPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEA 1672
             P  +  +   +++     I   + + P ++  AA     S +KV+      A A H   
Sbjct: 220  PPIQLPQSSSGNTI-----IPSNSGSSPNMNILAAAVTTPSSEKVASS----AGASH--V 268

Query: 1673 GRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEE-------RRGEPEED-----AP 1720
                 SSS  P      + SL+SP     L +               G   ED     A 
Sbjct: 269  SNPAVSSSSSPAFA---ISSLLSPASNPLLPQQASANSVFPSPLPNIGTTAEDLNSLSAL 325

Query: 1721 ASQR-GEPARIKIFEGGYKSNEEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDV 1779
            A QR  +P  +  FE    S+E +         K+ C  C       S L+ H+R+HT  
Sbjct: 326  AQQRKSKPPNVTAFEAKSTSDEAFF--------KHKCRFCAKVFGSDSALQIHLRSHTGE 377

Query: 1780 RPYVCKHCHFAFKTKGNLTKHMK 1802
            RP+ C  C   F TKGNL  H +
Sbjct: 378  RPFKCNICGNRFSTKGNLKVHFQ 400



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 39/152 (25%), Positives = 57/152 (37%), Gaps = 11/152 (7%)

Query: 1229 PTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLP 1288
            PTSS+ S G      +  +      + SHL Q   + A LA   A  S S   S   +LP
Sbjct: 168  PTSSSPSQGTLRTSANPLST-----LSSHLSQQLAAAAGLAQSLA--SQSASISGVKQLP 220

Query: 1289 PVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQG 1348
            P+  P SSS  T  P  +  +    +++  V       + S   A + +   +    S  
Sbjct: 221  PIQLPQSSSGNTIIPSNSGSSPNMNILAAAVTTPSSEKVASSAGASHVSNPAV----SSS 276

Query: 1349 SSATVALPKFEEPPSKGTTVCGADVHEVGPGP 1380
            SS   A+     P S       A  + V P P
Sbjct: 277  SSPAFAISSLLSPASNPLLPQQASANSVFPSP 308


>gi|118442837 sal-like 1 isoform a [Homo sapiens]
          Length = 1324

 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 109/453 (24%), Positives = 166/453 (36%), Gaps = 84/453 (18%)

Query: 38  PGSGTAATQESPAQEL---LAPQ--PFPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHI 92
           P  GT  T  +P   L   L+ Q     G +  L   S   +G +Q PP + P  +S + 
Sbjct: 270 PSQGTLRTSANPLSTLSSHLSQQLAAAAGLAQSLASQSASISGVKQLPPIQLPQSSSGNT 329

Query: 93  -------SQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSG------SFVAPGLH 139
                  S    + L  A  +P   +         + +P     S       S ++P  +
Sbjct: 330 IIPSNSGSSPNMNILAAAVTTPSSEKVASSAGASHVSNPAVSSSSSPAFAISSLLSPASN 389

Query: 140 PQSQLLPSHASI--IPPEDLPGVPKVFVPRPSQVSLKPTEEA--------HKKERKPQKP 189
           P   LLP  AS   + P  LP +        S  +L    ++          K    +  
Sbjct: 390 P---LLPQQASANSVFPSPLPNIGTTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAF 446

Query: 190 GKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAG 249
            K+ C++C++     S LQ H+RSHTGERP+ C  CG  F TK NL  H + H       
Sbjct: 447 FKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK------ 500

Query: 250 LASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSS 309
                  E YPH ++M   P  E             +    ++G P  +S  P++P+   
Sbjct: 501 -------EKYPH-IQMNPYPVPE-----------HLDNIPTSTGIPYGMSIPPEKPVT-- 539

Query: 310 GLYSSGSHSSSHERCSLSQSSTAQSLEDPP------PFV--EPSSEHPLSHK-PEDTHTI 360
                   S    +  L   +T+  L  PP      PF+  E  +  P+SH       ++
Sbjct: 540 --------SWLDTKPVLPTLTTSVGLPLPPTLPSLIPFIKTEEPAPIPISHSATSPPGSV 591

Query: 361 KQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFG 420
           K       S  + +      L   ++GST      +SE +    +   T + S       
Sbjct: 592 KSDSGGPESATRNL----GGLPEEAEGSTLPPSGGKSEESGMVTNSVPTASSSVLSSPAA 647

Query: 421 KCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVP 453
            CG  G  T     T T PLLPL +E   +  P
Sbjct: 648 DCGPAGSAT-----TFTNPLLPLMSEQFKAKFP 675



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 43/152 (28%), Positives = 64/152 (42%), Gaps = 15/152 (9%)

Query: 95   LPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRP-GPSGSFVAPGLHPQSQLLPSHAS--- 150
            L QH LT          H +     QL +P    GP+ +      +  S L+ +  +   
Sbjct: 1044 LKQHMLT----------HQMRDLPSQLFEPSSNLGPNQNSAVIPANSLSSLIKTEVNGFV 1093

Query: 151  IIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKH 210
             + P+D    P   VP    +S   T          + P ++ C  C +  +  S LQ H
Sbjct: 1094 HVSPQDSKDTPTSHVPS-GPLSSSATSPVLLPALPRRTPKQHYCNTCGKTFSSSSALQIH 1152

Query: 211  IRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242
             R+HTGE+P+ C  CG +F TK NL  H  +H
Sbjct: 1153 ERTHTGEKPFACTICGRAFTTKGNLKVHMGTH 1184



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 64/255 (25%), Positives = 98/255 (38%), Gaps = 20/255 (7%)

Query: 1767 SMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM---KSKAHSKKCQETGVLEELEAEE 1823
            S LK H RTHT  RP+ CK C  AF TKGNL  H    ++    +      + ++     
Sbjct: 719  SALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNA 778

Query: 1824 GTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPP 1883
                   +   G +         +S+  +SD+ S  DE   +D +   DE      E   
Sbjct: 779  VVLQQHIRMHMGGQIPNTPVPDSYSESMESDTGS-FDEKNFDDLDNFSDENMEDCPEGSI 837

Query: 1884 PGPPHALRA-----DSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPG 1938
            P  P +  A      SSP+  P    + A+     +  +   AE+L AS  S+ + S+ G
Sbjct: 838  PDTPKSADASQDSLSSSPL--PLEMSSIAALENQMKMINAGLAEQLQASLKSVENGSIEG 895

Query: 1939 --LPWLGPAPLGSVE-KDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQ 1995
              L     +  G +E +  GS    +  S  +  SPS            H     +  PQ
Sbjct: 896  DVLTNDSSSVGGDMESQSAGSPAISESTSSMQALSPSNST------QEFHKSPSIEEKPQ 949

Query: 1996 RCSPAREPQASAPSP 2010
            R  P+      +P+P
Sbjct: 950  RAVPSEFANGLSPTP 964



 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 27/66 (40%), Positives = 33/66 (50%), Gaps = 5/66 (7%)

Query: 177 EEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLY 236
           E   KK   P +     C  C R  +  S L+ H R+HTGERP+ C  CG +F TK NL 
Sbjct: 696 ENIDKKATDPNE-----CIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLK 750

Query: 237 KHRKSH 242
            H   H
Sbjct: 751 THYSVH 756



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 3/56 (5%)

Query: 1749 RGRGKY---VCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM 1801
            R RGK+    C+ CG      S L  H R+HT  RP++C  C+  F TKGNL +HM
Sbjct: 993  RDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHM 1048



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 23/52 (44%), Positives = 27/52 (51%)

Query: 194  CQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHR 245
            C  C +  A  S L  H RSHT ERP+ C  C   F TK NL +H  +H  R
Sbjct: 1003 CDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHMLTHQMR 1054



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 22/49 (44%), Positives = 27/49 (55%)

Query: 1753 KYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM 1801
            ++ C  CG      S L+ H RTHT  +P+ C  C  AF TKGNL  HM
Sbjct: 1133 QHYCNTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHM 1181



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 64/263 (24%), Positives = 101/263 (38%), Gaps = 39/263 (14%)

Query: 1556 SKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLH---TTTNVSWCYLNYI 1612
            + +  DLP+ + PS   L  TS+ P  +     S+++     L     + + S   +  +
Sbjct: 258  ASQNADLPTSSSPSQGTL-RTSANPLSTLSSHLSQQLAAAAGLAQSLASQSASISGVKQL 316

Query: 1613 KPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEA 1672
             P  +  +   +++     I   + + P ++  AA     S +KV+      A A H   
Sbjct: 317  PPIQLPQSSSGNTI-----IPSNSGSSPNMNILAAAVTTPSSEKVASS----AGASH--V 365

Query: 1673 GRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEE-------RRGEPEED-----AP 1720
                 SSS  P      + SL+SP     L +               G   ED     A 
Sbjct: 366  SNPAVSSSSSPAFA---ISSLLSPASNPLLPQQASANSVFPSPLPNIGTTAEDLNSLSAL 422

Query: 1721 ASQR-GEPARIKIFEGGYKSNEEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDV 1779
            A QR  +P  +  FE    S+E +         K+ C  C       S L+ H+R+HT  
Sbjct: 423  AQQRKSKPPNVTAFEAKSTSDEAFF--------KHKCRFCAKVFGSDSALQIHLRSHTGE 474

Query: 1780 RPYVCKHCHFAFKTKGNLTKHMK 1802
            RP+ C  C   F TKGNL  H +
Sbjct: 475  RPFKCNICGNRFSTKGNLKVHFQ 497



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 39/152 (25%), Positives = 57/152 (37%), Gaps = 11/152 (7%)

Query: 1229 PTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLP 1288
            PTSS+ S G      +  +      + SHL Q   + A LA   A  S S   S   +LP
Sbjct: 265  PTSSSPSQGTLRTSANPLST-----LSSHLSQQLAAAAGLAQSLA--SQSASISGVKQLP 317

Query: 1289 PVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQG 1348
            P+  P SSS  T  P  +  +    +++  V       + S   A + +   +    S  
Sbjct: 318  PIQLPQSSSGNTIIPSNSGSSPNMNILAAAVTTPSSEKVASSAGASHVSNPAV----SSS 373

Query: 1349 SSATVALPKFEEPPSKGTTVCGADVHEVGPGP 1380
            SS   A+     P S       A  + V P P
Sbjct: 374  SSPAFAISSLLSPASNPLLPQQASANSVFPSP 405


>gi|40807465 zinc finger protein 341 [Homo sapiens]
          Length = 847

 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 82/356 (23%), Positives = 123/356 (34%), Gaps = 82/356 (23%)

Query: 3   PEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGP 62
           P Q      ++ G P +    G  +    S++ P  GSGT   Q       L  QP+   
Sbjct: 193 PPQPPPPPPQSLGPPGRPNPGGNGVVEVYSAAAPLAGSGTVEIQ------ALGMQPY--- 243

Query: 63  SSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLV 122
                                PP+E      + P +P TP   SPGK             
Sbjct: 244 ---------------------PPLEVPNQCVEPPVYP-TPTVYSPGKQ------------ 269

Query: 123 DPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKK 182
                     F   G +P + +  +    +   D P   K    R ++ + KP       
Sbjct: 270 ---------GFKPKGPNPAAPMTSATGGTVATFDSPATLKT---RRAKAAGKP------- 310

Query: 183 ERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242
                K  K  C YC +   K   LQ+HIRSHTGE+P+ C  CG +F  KSN+ KH ++H
Sbjct: 311 -----KAQKLKCSYCDKSFTKNFDLQQHIRSHTGEKPFQCIACGRAFAQKSNVKKHMQTH 365

Query: 243 AHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRP 302
               K       GG +  + + ++ +      +         E+E S   G P   +P+P
Sbjct: 366 ----KVWPPGHSGGTVSRNSVTVQVMALNPSRQ---------EDEESTGLGQPLPGAPQP 412

Query: 303 KQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTH 358
           +   LS+     G    S +   +  S   Q              H   HK E  +
Sbjct: 413 Q--ALSTAGEEEGDKPESKQVVLIDSSYLCQFCPSKFSTYFQLKSHMTQHKNEQVY 466



 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 21/164 (12%)

Query: 191 KYICQY-----CSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHR 245
           KY C +     CS+   +P  L+ HI SH+G + + C  C  SF  +++L +H+++H   
Sbjct: 642 KYKCPFSTHTGCSKEFNRPDKLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAHTGN 701

Query: 246 IK---AGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRP 302
            K   AG A G     Y         P ++ +  T           S  SG    L+P P
Sbjct: 702 YKFRCAGCAKGFSRHKYLKDHRCRLGPQKDKDLQTRRPPQRRAAPRSCGSGGRKVLTPLP 761

Query: 303 KQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSS 346
             PL    L  +G+                +++   PPF EP +
Sbjct: 762 -DPLGLEELKDTGA------------GLVPEAVPGKPPFAEPDA 792



 Score = 45.1 bits (105), Expect = 9e-04
 Identities = 18/53 (33%), Positives = 27/53 (50%)

Query: 190 GKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242
           G++ CQ C +   +   L+ H   H+GE+PY C  C  +F  K  L +H   H
Sbjct: 585 GRFKCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIH 637



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 20/51 (39%), Positives = 28/51 (54%)

Query: 1753 KYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKS 1803
            K  C  C     K   L++HIR+HT  +P+ C  C  AF  K N+ KHM++
Sbjct: 314  KLKCSYCDKSFTKNFDLQQHIRSHTGEKPFQCIACGRAFAQKSNVKKHMQT 364



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 4/92 (4%)

Query: 159 GVPKVFVPRPSQVSLKPTEEAHKKERKPQK--PGKYICQYCSRPCAKPSVLQKHIRSHTG 216
           G P    P+P  +S    EE  K E K        Y+CQ+C    +    L+ H+  H  
Sbjct: 403 GQPLPGAPQPQALSTAGEEEGDKPESKQVVLIDSSYLCQFCPSKFSTYFQLKSHMTQHKN 462

Query: 217 ERPYPC--GPCGFSFKTKSNLYKHRKSHAHRI 246
           E+ Y C    C  +F       +H KSH   +
Sbjct: 463 EQVYKCVVKSCAQTFPKLDTFLEHIKSHQEEL 494



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 22/76 (28%), Positives = 38/76 (50%)

Query: 168 PSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGF 227
           PS+ S     ++H  + K ++  K + + C++   K     +HI+SH  E  Y C  CG 
Sbjct: 444 PSKFSTYFQLKSHMTQHKNEQVYKCVVKSCAQTFPKLDTFLEHIKSHQEELSYRCHLCGK 503

Query: 228 SFKTKSNLYKHRKSHA 243
            F +  +L  H+ SH+
Sbjct: 504 DFPSLYDLGVHQYSHS 519



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 17/50 (34%), Positives = 25/50 (50%)

Query: 1752 GKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM 1801
            G++ C+ C    ++   LK H   H+  +PY C  C  AF  K  L +HM
Sbjct: 585  GRFKCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHM 634



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 38/152 (25%), Positives = 59/152 (38%), Gaps = 19/152 (12%)

Query: 1654 KQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEERRG 1713
            K  V K   T    P   +G  V  +S       V + +L +P  Q+D     +E    G
Sbjct: 355  KSNVKKHMQTHKVWPPGHSGGTVSRNS-----VTVQVMAL-NPSRQED-----EESTGLG 403

Query: 1714 EPEEDAPASQRGEPARIKIFEGGYKSNEEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHI 1773
            +P   AP  Q    A  +  EG    +++ V +       Y+C+ C  +      LK H+
Sbjct: 404  QPLPGAPQPQALSTAGEE--EGDKPESKQVVLIDS----SYLCQFCPSKFSTYFQLKSHM 457

Query: 1774 RTHTDVRPYVC--KHCHFAFKTKGNLTKHMKS 1803
              H + + Y C  K C   F       +H+KS
Sbjct: 458  TQHKNEQVYKCVVKSCAQTFPKLDTFLEHIKS 489



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 37/133 (27%), Positives = 49/133 (36%), Gaps = 10/133 (7%)

Query: 748 NLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFE 807
           N P  +T S A  S   PS   PT  Q + P P +   S       S  I  +   +   
Sbjct: 79  NAPALATVSLATNSIYPPSA-APTAVQ-QAPTPANRQISTYITVPPSPLIQTLVQGNILV 136

Query: 808 KSDSLEQP-SGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDR 866
             D L    S     D+P+ Q   PPP     + HS+   L + P    P       P  
Sbjct: 137 SDDVLMSAMSAFTSLDQPMPQ--GPPPVQSSLNMHSVPSYLTQPPPPPPPP-----PPLP 189

Query: 867 PDTEPEPPPKEPE 879
           P   P+PPP  P+
Sbjct: 190 PPPPPQPPPPPPQ 202



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 4/60 (6%)

Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK--KCQ 1811
            Y C +C  +   P  L+ H++T T   P  C HC   F  +  L +H+ +       KCQ
Sbjct: 533  YKCVKCVNKYSTPEALEHHLQTATHNFP--CPHCQKVFPCERYLRRHLPTHGSGGRFKCQ 590


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 29/64 (45%), Positives = 42/64 (65%), Gaps = 2/64 (3%)

Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239
           H++    +KP  Y C YC++  ++ S L +H R+HTGERPY CG CG  F   SNL +HR
Sbjct: 531 HQRIHTGEKP--YACSYCAKRFSESSALVQHQRTHTGERPYACGDCGKRFSVSSNLLRHR 588

Query: 240 KSHA 243
           ++H+
Sbjct: 589 RTHS 592



 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 51/179 (28%), Positives = 81/179 (45%), Gaps = 20/179 (11%)

Query: 68  EGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRP 127
           E  Q++  QQ+   +  P+E      ++ Q  LTP      +PE  LE     LV     
Sbjct: 373 EQQQQQLEQQEVQLELTPVELGAQQQEV-QLELTPV-----QPELQLE-----LVPAAGG 421

Query: 128 GPSGSFVAPG---LHPQSQLLPSHASIIPPEDLPGVPKVFVPRPS-QVSLKPTEEAHKKE 183
           G +    AP    + P   ++     ++P    P V  V +P P+   +L P   A ++ 
Sbjct: 422 GGAAVPGAPAAVVVAPPGYVVVQELMVLPAVAAPAV--VAIPGPAGSAALTP---ARQRR 476

Query: 184 RKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242
           R+  +    IC  C +  ++ + L +H  +HTGERP+ CG CG  F   SNL  H++ H
Sbjct: 477 RRRARDRPTICGECGKGFSRSTDLVRHQATHTGERPHRCGECGKGFSQHSNLVTHQRIH 535



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 2/67 (2%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKK 1809
            G   Y C  C  R  + S L +H RTHT  RPY C  C   F    NL +H ++ +  + 
Sbjct: 537  GEKPYACSYCAKRFSESSALVQHQRTHTGERPYACGDCGKRFSVSSNLLRHRRTHSGERP 596

Query: 1810 --CQETG 1814
              C++ G
Sbjct: 597  YVCEDCG 603



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 7/77 (9%)

Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKH- 238
           H++    ++P  Y C  C +  +  S L +H R+H+GERPY C  CG  F+ K  + +H 
Sbjct: 559 HQRTHTGERP--YACGDCGKRFSVSSNLLRHRRTHSGERPYVCEDCGERFRHKVQIRRHE 616

Query: 239 RKSHAHRIKAGLASGMG 255
           R+ H     AG + G+G
Sbjct: 617 RQLHG----AGRSRGLG 629



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 23/67 (34%), Positives = 35/67 (52%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKK 1809
            G   Y C +CG R    S L +H RTH+  RPYVC+ C   F+ K  + +H +    + +
Sbjct: 565  GERPYACGDCGKRFSVSSNLLRHRRTHSGERPYVCEDCGERFRHKVQIRRHERQLHGAGR 624

Query: 1810 CQETGVL 1816
             +  G+L
Sbjct: 625  SRGLGLL 631



 Score = 45.1 bits (105), Expect = 9e-04
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239
           H+     ++P +  C  C +  ++ S L  H R HTGE+PY C  C   F   S L +H+
Sbjct: 503 HQATHTGERPHR--CGECGKGFSQHSNLVTHQRIHTGEKPYACSYCAKRFSESSALVQHQ 560

Query: 240 KSH 242
           ++H
Sbjct: 561 RTH 563



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 31/118 (26%), Positives = 49/118 (41%), Gaps = 9/118 (7%)

Query: 1688 VHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSNEEYVYVR 1747
            V  P++V+  G    A +    +RR     D P    GE  +      G+  + + V  +
Sbjct: 452  VAAPAVVAIPGPAGSAALTPARQRRRRRARDRPTIC-GECGK------GFSRSTDLVRHQ 504

Query: 1748 GRGRGK--YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKS 1803
                G+  + C ECG    + S L  H R HT  +PY C +C   F     L +H ++
Sbjct: 505  ATHTGERPHRCGECGKGFSQHSNLVTHQRIHTGEKPYACSYCAKRFSESSALVQHQRT 562


>gi|193082982 zinc finger protein 837 isoform 1 [Homo sapiens]
          Length = 531

 Score = 68.9 bits (167), Expect = 6e-11
 Identities = 30/66 (45%), Positives = 42/66 (63%), Gaps = 2/66 (3%)

Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239
           H++    +KP  YIC+ C +   +   L +H+R+HTGERPY CG CG +F  +SNL +HR
Sbjct: 465 HERLHSGEKP--YICRDCGKAFVRNCSLVRHLRTHTGERPYACGDCGRAFSQRSNLNEHR 522

Query: 240 KSHAHR 245
           K H  R
Sbjct: 523 KRHGGR 528



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 62/253 (24%), Positives = 88/253 (34%), Gaps = 49/253 (19%)

Query: 36  PYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPK------------- 82
           P PG+  +A      +E   P     P  V+ EG Q + G  + P +             
Sbjct: 74  PGPGTRHSAGTRPLVREPCGPTSSQNPELVIPEGLQAREGPCRSPARGGDCSRNSCLAWH 133

Query: 83  -------RPPI---------------EASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQ 120
                   PP+                  VH    P  P T A   P  P+    G    
Sbjct: 134 RGAPAGETPPVCDPCPERIQNHPRTQLCEVHTDCWPCQPGTGAPTCPRTPKPTSRGRNPL 193

Query: 121 LVDPMRPGPSGSFVAPGLH-PQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPT--- 176
           +  P       +F    L  PQ +L  +      P       K F P   Q + K     
Sbjct: 194 VEQPRACACGEAFAWRALRIPQERLQATEE----PRPCARCGKRFRPNQQQQAGKSPPVC 249

Query: 177 ----EEAHKKERKPQKPGK--YICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFK 230
               + +  +   P  P +  Y C  C +   + S L +H R HTGERPY C  CG +F 
Sbjct: 250 PECGQTSRPRPIVPDPPAQRLYACDECGKAFTRTSSLLQHQRIHTGERPYECAECGKAFV 309

Query: 231 TKSNLYKHRKSHA 243
             S LY+H+K+H+
Sbjct: 310 RCSGLYRHQKTHS 322



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 25/64 (39%), Positives = 35/64 (54%), Gaps = 2/64 (3%)

Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239
           H++     KP  Y C  C +     S L +H R+HTGERPY C  CG +F+  S L +H 
Sbjct: 409 HQRTHSSAKP--YACPLCEKAFKGRSGLVQHQRAHTGERPYGCSECGKTFRGCSELRQHE 466

Query: 240 KSHA 243
           + H+
Sbjct: 467 RLHS 470



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 22/53 (41%), Positives = 29/53 (54%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMK 1802
            G   Y+C +CG    +   L +H+RTHT  RPY C  C  AF  + NL +H K
Sbjct: 471  GEKPYICRDCGKAFVRNCSLVRHLRTHTGERPYACGDCGRAFSQRSNLNEHRK 523



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 24/57 (42%), Positives = 36/57 (63%), Gaps = 2/57 (3%)

Query: 187 QKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHA 243
           +KP  Y C  C++     S L +H R HTGE+PY C  CG +F  +SNL +H+++H+
Sbjct: 360 EKP--YECADCAKAFGLFSHLVEHRRVHTGEKPYACPECGKAFNQRSNLSRHQRTHS 414



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 2/67 (2%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKK 1809
            G   Y C ECG    + S L +H RTH+  +PY C  C  AFK +  L +H ++    + 
Sbjct: 387  GEKPYACPECGKAFNQRSNLSRHQRTHSSAKPYACPLCEKAFKGRSGLVQHQRAHTGERP 446

Query: 1810 --CQETG 1814
              C E G
Sbjct: 447  YGCSECG 453



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 21/63 (33%), Positives = 36/63 (57%), Gaps = 2/63 (3%)

Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239
           H++    +KP  Y C  C +   + S L +H R+H+  +PY C  C  +FK +S L +H+
Sbjct: 381 HRRVHTGEKP--YACPECGKAFNQRSNLSRHQRTHSSAKPYACPLCEKAFKGRSGLVQHQ 438

Query: 240 KSH 242
           ++H
Sbjct: 439 RAH 441



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 2/64 (3%)

Query: 1747 RGRGRGK--YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSK 1804
            RG G G+  Y C +C       S L +H R HT  +PY C  C  AF  + NL++H ++ 
Sbjct: 354  RGSGAGEKPYECADCAKAFGLFSHLVEHRRVHTGEKPYACPECGKAFNQRSNLSRHQRTH 413

Query: 1805 AHSK 1808
            + +K
Sbjct: 414  SSAK 417



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 2/63 (3%)

Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239
           H++    ++P  Y C  C +     S L++H R H+GE+PY C  CG +F    +L +H 
Sbjct: 437 HQRAHTGERP--YGCSECGKTFRGCSELRQHERLHSGEKPYICRDCGKAFVRNCSLVRHL 494

Query: 240 KSH 242
           ++H
Sbjct: 495 RTH 497



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 2/61 (3%)

Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQET 1813
            Y C+ECG    + S L +H R HT  RPY C  C  AF     L +H K+  HS +    
Sbjct: 271  YACDECGKAFTRTSSLLQHQRIHTGERPYECAECGKAFVRCSGLYRHQKT--HSAERHRR 328

Query: 1814 G 1814
            G
Sbjct: 329  G 329



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 19/54 (35%), Positives = 31/54 (57%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKS 1803
            G   Y C ECG   +  S L++H R H+  +PY+C+ C  AF    +L +H+++
Sbjct: 443  GERPYGCSECGKTFRGCSELRQHERLHSGEKPYICRDCGKAFVRNCSLVRHLRT 496



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 2/63 (3%)

Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKK--CQ 1811
            Y C  C    K  S L +H R HT  RPY C  C   F+    L +H +  +  K   C+
Sbjct: 419  YACPLCEKAFKGRSGLVQHQRAHTGERPYGCSECGKTFRGCSELRQHERLHSGEKPYICR 478

Query: 1812 ETG 1814
            + G
Sbjct: 479  DCG 481



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 1/81 (1%)

Query: 162 KVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYP 221
           K FV        + T  A +  R P    +     C  PC   S       S  GE+PY 
Sbjct: 306 KAFVRCSGLYRHQKTHSAERHRRGPVLARRAFRLGCP-PCGDYSERSPRRGSGAGEKPYE 364

Query: 222 CGPCGFSFKTKSNLYKHRKSH 242
           C  C  +F   S+L +HR+ H
Sbjct: 365 CADCAKAFGLFSHLVEHRRVH 385


>gi|193082980 zinc finger protein 837 isoform 2 [Homo sapiens]
          Length = 531

 Score = 68.9 bits (167), Expect = 6e-11
 Identities = 30/66 (45%), Positives = 42/66 (63%), Gaps = 2/66 (3%)

Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239
           H++    +KP  YIC+ C +   +   L +H+R+HTGERPY CG CG +F  +SNL +HR
Sbjct: 465 HERLHSGEKP--YICRDCGKAFVRNCSLVRHLRTHTGERPYACGDCGRAFSQRSNLNEHR 522

Query: 240 KSHAHR 245
           K H  R
Sbjct: 523 KRHGGR 528



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 62/253 (24%), Positives = 88/253 (34%), Gaps = 49/253 (19%)

Query: 36  PYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPK------------- 82
           P PG+  +A      +E   P     P  V+ EG Q + G  + P +             
Sbjct: 74  PGPGTRHSAGTRPLVREPCGPTSSQNPELVIPEGLQAREGPCRSPARGGDCSRNSCLAWH 133

Query: 83  -------RPPI---------------EASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQ 120
                   PP+                  VH    P  P T A   P  P+    G    
Sbjct: 134 RGAPAGETPPVCDPCPERIQNHPRTQLCEVHTDCWPCQPGTGAPTCPRTPKPTSRGRNPL 193

Query: 121 LVDPMRPGPSGSFVAPGLH-PQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPT--- 176
           +  P       +F    L  PQ +L  +      P       K F P   Q + K     
Sbjct: 194 VEQPRACACGEAFAWRALRIPQERLQATEE----PRPCARCGKRFRPNQQQQAGKSPPVC 249

Query: 177 ----EEAHKKERKPQKPGK--YICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFK 230
               + +  +   P  P +  Y C  C +   + S L +H R HTGERPY C  CG +F 
Sbjct: 250 PECGQTSRPRPIVPDPPAQRLYACDECGKAFTRTSSLLQHQRIHTGERPYECAECGKAFV 309

Query: 231 TKSNLYKHRKSHA 243
             S LY+H+K+H+
Sbjct: 310 RCSGLYRHQKTHS 322



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 25/64 (39%), Positives = 35/64 (54%), Gaps = 2/64 (3%)

Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239
           H++     KP  Y C  C +     S L +H R+HTGERPY C  CG +F+  S L +H 
Sbjct: 409 HQRTHSSAKP--YACPLCEKAFKGRSGLVQHQRAHTGERPYGCSECGKTFRGCSELRQHE 466

Query: 240 KSHA 243
           + H+
Sbjct: 467 RLHS 470



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 22/53 (41%), Positives = 29/53 (54%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMK 1802
            G   Y+C +CG    +   L +H+RTHT  RPY C  C  AF  + NL +H K
Sbjct: 471  GEKPYICRDCGKAFVRNCSLVRHLRTHTGERPYACGDCGRAFSQRSNLNEHRK 523



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 24/57 (42%), Positives = 36/57 (63%), Gaps = 2/57 (3%)

Query: 187 QKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHA 243
           +KP  Y C  C++     S L +H R HTGE+PY C  CG +F  +SNL +H+++H+
Sbjct: 360 EKP--YECADCAKAFGLFSHLVEHRRVHTGEKPYACPECGKAFNQRSNLSRHQRTHS 414



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 2/67 (2%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKK 1809
            G   Y C ECG    + S L +H RTH+  +PY C  C  AFK +  L +H ++    + 
Sbjct: 387  GEKPYACPECGKAFNQRSNLSRHQRTHSSAKPYACPLCEKAFKGRSGLVQHQRAHTGERP 446

Query: 1810 --CQETG 1814
              C E G
Sbjct: 447  YGCSECG 453



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 21/63 (33%), Positives = 36/63 (57%), Gaps = 2/63 (3%)

Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239
           H++    +KP  Y C  C +   + S L +H R+H+  +PY C  C  +FK +S L +H+
Sbjct: 381 HRRVHTGEKP--YACPECGKAFNQRSNLSRHQRTHSSAKPYACPLCEKAFKGRSGLVQHQ 438

Query: 240 KSH 242
           ++H
Sbjct: 439 RAH 441



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 2/64 (3%)

Query: 1747 RGRGRGK--YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSK 1804
            RG G G+  Y C +C       S L +H R HT  +PY C  C  AF  + NL++H ++ 
Sbjct: 354  RGSGAGEKPYECADCAKAFGLFSHLVEHRRVHTGEKPYACPECGKAFNQRSNLSRHQRTH 413

Query: 1805 AHSK 1808
            + +K
Sbjct: 414  SSAK 417



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 2/63 (3%)

Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239
           H++    ++P  Y C  C +     S L++H R H+GE+PY C  CG +F    +L +H 
Sbjct: 437 HQRAHTGERP--YGCSECGKTFRGCSELRQHERLHSGEKPYICRDCGKAFVRNCSLVRHL 494

Query: 240 KSH 242
           ++H
Sbjct: 495 RTH 497



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 2/61 (3%)

Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQET 1813
            Y C+ECG    + S L +H R HT  RPY C  C  AF     L +H K+  HS +    
Sbjct: 271  YACDECGKAFTRTSSLLQHQRIHTGERPYECAECGKAFVRCSGLYRHQKT--HSAERHRR 328

Query: 1814 G 1814
            G
Sbjct: 329  G 329



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 19/54 (35%), Positives = 31/54 (57%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKS 1803
            G   Y C ECG   +  S L++H R H+  +PY+C+ C  AF    +L +H+++
Sbjct: 443  GERPYGCSECGKTFRGCSELRQHERLHSGEKPYICRDCGKAFVRNCSLVRHLRT 496



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 2/63 (3%)

Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKK--CQ 1811
            Y C  C    K  S L +H R HT  RPY C  C   F+    L +H +  +  K   C+
Sbjct: 419  YACPLCEKAFKGRSGLVQHQRAHTGERPYGCSECGKTFRGCSELRQHERLHSGEKPYICR 478

Query: 1812 ETG 1814
            + G
Sbjct: 479  DCG 481



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 1/81 (1%)

Query: 162 KVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYP 221
           K FV        + T  A +  R P    +     C  PC   S       S  GE+PY 
Sbjct: 306 KAFVRCSGLYRHQKTHSAERHRRGPVLARRAFRLGCP-PCGDYSERSPRRGSGAGEKPYE 364

Query: 222 CGPCGFSFKTKSNLYKHRKSH 242
           C  C  +F   S+L +HR+ H
Sbjct: 365 CADCAKAFGLFSHLVEHRRVH 385


>gi|4508009 zinc finger protein 177 [Homo sapiens]
          Length = 321

 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)

Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239
           HK+    +KP  Y C+ C +    PS LQKH+R+HTGE+PY C  CG +F  +S+L KH 
Sbjct: 170 HKRTHTGEKP--YDCKECGKAFTVPSSLQKHVRTHTGEKPYECSDCGKAFIDQSSLKKHT 227

Query: 240 KSH 242
           +SH
Sbjct: 228 RSH 230



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 28/65 (43%), Positives = 37/65 (56%), Gaps = 2/65 (3%)

Query: 178 EAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYK 237
           + H +    +KP  Y C  C +     S L+KH RSHTGE+PY C  CG SF T S L  
Sbjct: 196 QKHVRTHTGEKP--YECSDCGKAFIDQSSLKKHTRSHTGEKPYECNQCGKSFSTGSYLIV 253

Query: 238 HRKSH 242
           H+++H
Sbjct: 254 HKRTH 258



 Score = 58.5 bits (140), Expect = 8e-08
 Identities = 28/67 (41%), Positives = 37/67 (55%), Gaps = 2/67 (2%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK- 1808
            G   Y C+ECG     PS L+KH+RTHT  +PY C  C  AF  + +L KH +S    K 
Sbjct: 176  GEKPYDCKECGKAFTVPSSLQKHVRTHTGEKPYECSDCGKAFIDQSSLKKHTRSHTGEKP 235

Query: 1809 -KCQETG 1814
             +C + G
Sbjct: 236  YECNQCG 242



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 2/63 (3%)

Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239
           H +    +KP  Y C +C +  ++ S L  H R+HTGE+PY C  CG +F   S+L KH 
Sbjct: 142 HMRSHTGEKP--YECDHCGKSFSQSSHLNVHKRTHTGEKPYDCKECGKAFTVPSSLQKHV 199

Query: 240 KSH 242
           ++H
Sbjct: 200 RTH 202



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 24/51 (47%), Positives = 32/51 (62%)

Query: 192 YICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242
           Y C  C +     S L+KH+RSHTGE+PY C  CG SF   S+L  H+++H
Sbjct: 124 YECSDCGKAFIFQSSLKKHMRSHTGEKPYECDHCGKSFSQSSHLNVHKRTH 174



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 2/63 (3%)

Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239
           HK+    +K   Y C+ C +     S L+ H+R+HTGE+PY C  C  +F T +NL  H+
Sbjct: 254 HKRTHTGEKT--YECKECGKAFRNSSCLRVHVRTHTGEKPYKCFQCEKAFSTSTNLIMHK 311

Query: 240 KSH 242
           + H
Sbjct: 312 RIH 314



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 27/67 (40%), Positives = 34/67 (50%), Gaps = 3/67 (4%)

Query: 1739 SNEEYVYVRGR---GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKG 1795
            S   Y+ V  R   G   Y C+ECG   +  S L+ H+RTHT  +PY C  C  AF T  
Sbjct: 246  STGSYLIVHKRTHTGEKTYECKECGKAFRNSSCLRVHVRTHTGEKPYKCFQCEKAFSTST 305

Query: 1796 NLTKHMK 1802
            NL  H +
Sbjct: 306  NLIMHKR 312



 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 25/67 (37%), Positives = 34/67 (50%), Gaps = 2/67 (2%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK- 1808
            G   Y C +CG      S LKKH+R+HT  +PY C HC  +F    +L  H ++    K 
Sbjct: 120  GEMPYECSDCGKAFIFQSSLKKHMRSHTGEKPYECDHCGKSFSQSSHLNVHKRTHTGEKP 179

Query: 1809 -KCQETG 1814
              C+E G
Sbjct: 180  YDCKECG 186



 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 25/67 (37%), Positives = 34/67 (50%), Gaps = 2/67 (2%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK- 1808
            G   Y C+ CG    + S L  H RTHT  +PY CK C  AF    +L KH+++    K 
Sbjct: 148  GEKPYECDHCGKSFSQSSHLNVHKRTHTGEKPYDCKECGKAFTVPSSLQKHVRTHTGEKP 207

Query: 1809 -KCQETG 1814
             +C + G
Sbjct: 208  YECSDCG 214



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 2/67 (2%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK- 1808
            G   Y C +CG      S LKKH R+HT  +PY C  C  +F T   L  H ++    K 
Sbjct: 204  GEKPYECSDCGKAFIDQSSLKKHTRSHTGEKPYECNQCGKSFSTGSYLIVHKRTHTGEKT 263

Query: 1809 -KCQETG 1814
             +C+E G
Sbjct: 264  YECKECG 270



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 9/89 (10%)

Query: 154 PEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRS 213
           P +     K F+    Q SLK    +H  E+       Y C  C +  +  S L  H R+
Sbjct: 207 PYECSDCGKAFI---DQSSLKKHTRSHTGEKP------YECNQCGKSFSTGSYLIVHKRT 257

Query: 214 HTGERPYPCGPCGFSFKTKSNLYKHRKSH 242
           HTGE+ Y C  CG +F+  S L  H ++H
Sbjct: 258 HTGEKTYECKECGKAFRNSSCLRVHVRTH 286



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 23/63 (36%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK- 1808
            G   Y C +CG      S L  H RTHT  + Y CK C  AF+    L  H+++    K 
Sbjct: 232  GEKPYECNQCGKSFSTGSYLIVHKRTHTGEKTYECKECGKAFRNSSCLRVHVRTHTGEKP 291

Query: 1809 -KC 1810
             KC
Sbjct: 292  YKC 294



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 16/32 (50%), Positives = 23/32 (71%)

Query: 211 IRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242
           +R+H+GE PY C  CG +F  +S+L KH +SH
Sbjct: 115 VRTHSGEMPYECSDCGKAFIFQSSLKKHMRSH 146



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 2/44 (4%)

Query: 1773 IRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK--KCQETG 1814
            +RTH+   PY C  C  AF  + +L KHM+S    K  +C   G
Sbjct: 115  VRTHSGEMPYECSDCGKAFIFQSSLKKHMRSHTGEKPYECDHCG 158


>gi|138175817 zinc finger protein 236 [Homo sapiens]
          Length = 1845

 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 80/383 (20%), Positives = 140/383 (36%), Gaps = 40/383 (10%)

Query: 45   TQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQ-HPLTPA 103
            T+E+   + LA QP                G   +  ++ P + S   + LPQ   +T  
Sbjct: 830  TEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDT 889

Query: 104  F-MSPGKP--EHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGV 160
            +   P  P  + L + ST +             ++   H QS L        P  D   V
Sbjct: 890  YHQQPQFPPVQQLQDSSTLE----------SQALSTSFHQQSLLQA------PSSDGMNV 933

Query: 161  PKVFVPRPSQVSLKPTEEAHK--KERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGER 218
                +   SQ  L    +  +  ++ + Q    Y C YC++   K S L++H+RSHTGE+
Sbjct: 934  TTRLIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEK 993

Query: 219  PYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTE 278
            PY C  CG  F +   L  H K+H   +KA   S        +G     +      +P +
Sbjct: 994  PYKCKLCGRGFVSSGVLKSHEKTHT-GVKAFSCSVCNASFTTNGSLTRHMATHMSMKPYK 1052

Query: 279  GESTDSEEETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDP 338
                +    T+       +        + ++G    G      E     ++++ +S  + 
Sbjct: 1053 CPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNASRKSRPEV 1112

Query: 339  PPFVEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSE 398
              F E  +      +P+++ T+ +K+ ++ +  K  I E                  R +
Sbjct: 1113 ITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISE-----------------LRDK 1155

Query: 399  SAEQQVSPPNTNAKSYAEIIFGK 421
             AE Q  P + N  +Y    F K
Sbjct: 1156 QAELQDEPKHANCCTYCPKSFKK 1178



 Score = 62.4 bits (150), Expect = 5e-09
 Identities = 38/96 (39%), Positives = 46/96 (47%), Gaps = 4/96 (4%)

Query: 149  ASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYI--CQYCSRPCAKPSV 206
            A I P E      KV V   S        E   K+ + Q   K+   C YC +   KPS 
Sbjct: 1124 AKIRPQESATVSEKVLVQ--SAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSD 1181

Query: 207  LQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242
            L +H+R HTGE+PY C  CG SF  KS L  H K+H
Sbjct: 1182 LVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTH 1217



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 27/56 (48%), Positives = 33/56 (58%)

Query: 187  QKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242
            QKP  + C  C +  AKPS L++H R HTGERP+ C  C  +F  KS L  H K H
Sbjct: 1717 QKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKH 1772



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 24/51 (47%), Positives = 29/51 (56%)

Query: 192 YICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242
           Y C +C +   KPS L +HIR HTGERP+ C  CG +F  K  L  H   H
Sbjct: 197 YSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKH 247



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 39/128 (30%), Positives = 58/128 (45%), Gaps = 10/128 (7%)

Query: 124 PMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKE 183
           P    P+ S  A    P +Q  P  +S+   +  P   +    + S   L   E+   K+
Sbjct: 406 PAAAHPNDSCHAKTSAPHAQN-PDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKK 464

Query: 184 RKPQKPGK---------YICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSN 234
           + P  PG          ++C YC++   KPS L +HIR HT E+P+ C  C  +F  KS 
Sbjct: 465 KSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKST 524

Query: 235 LYKHRKSH 242
           L  H K+H
Sbjct: 525 LTAHIKTH 532



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 35/104 (33%), Positives = 48/104 (46%), Gaps = 9/104 (8%)

Query: 174  KPTE-EAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTK 232
            KP++ E H +    ++P  + C  C +   + S LQ H++ HTGERPY C  C   F  K
Sbjct: 1733 KPSQLERHSRIHTGERP--FHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQK 1790

Query: 233  SNLYKHRKSHAHRIKAGLASGMG-----GEMYPHGLEMERIPGE 271
            SN+  H K  AH     L    G     GE     L +E +  E
Sbjct: 1791 SNMKLHMK-RAHSYAGALQESAGHPEQDGEELSRTLHLEEVVQE 1833



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 12/224 (5%)

Query: 192 YICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHA--HRIKAG 249
           Y C YC R   K   L++HIRSHTGE+P+ C  CG  F +   L  H ++H      K  
Sbjct: 657 YKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCL 716

Query: 250 LASG---MGGEMYPH-GLEMERIPGE-EFEEPTEGESTDSEEETSATSGHPAELSPRPKQ 304
           + +G    GG +  H G+  +  P    + + T   S + ++       H  EL+ + +Q
Sbjct: 717 ICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKT---HRYELAQQLQQ 773

Query: 305 PLLSSGLYSSGSHSSSHERCSLSQ-SSTAQSLEDPPPFVEPSSEHPLSHKPED-THTIKQ 362
              ++ +  S     S +  +  Q    +  L      V  + E  L  +P+    T + 
Sbjct: 774 HQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGTEEA 833

Query: 363 KLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSP 406
            L  +L+++    DE  F++P          F     A+Q   P
Sbjct: 834 GLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEP 877



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 24/48 (50%), Positives = 27/48 (56%)

Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM 1801
            Y C  CG   +KPS L +HIR HT  RP+ C  C  AF  KG L  HM
Sbjct: 197  YSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHM 244



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 42/154 (27%), Positives = 70/154 (45%), Gaps = 12/154 (7%)

Query: 1660 ETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDA 1719
            E+  ++T+ H ++    PSS      T      L+    Q++L    +  +   + E+ +
Sbjct: 909  ESQALSTSFHQQSLLQAPSSDGMNVTTR-----LIQESSQEELDLQAQGSQFLEDNEDQS 963

Query: 1720 PASQRGEPARIKIFEGGYKSNEEYVYVRGR-GRGKYVCEECGIRCKKPSMLKKHIRTHTD 1778
              S R +       +G  KS+    +VR   G   Y C+ CG       +LK H +THT 
Sbjct: 964  RRSYRCDYCN----KGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTG 1019

Query: 1779 VRPYVCKHCHFAFKTKGNLTKHMKSKAHSK--KC 1810
            V+ + C  C+ +F T G+LT+HM +    K  KC
Sbjct: 1020 VKAFSCSVCNASFTTNGSLTRHMATHMSMKPYKC 1053



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 26/60 (43%), Positives = 33/60 (55%), Gaps = 2/60 (3%)

Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK--KCQ 1811
            +VC  C    +KPS L +HIR HT  +P+ C  C  AF  K  LT H+K+    K  KCQ
Sbjct: 482  HVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQ 541



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 46/203 (22%), Positives = 84/203 (41%), Gaps = 14/203 (6%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKK 1809
            G   + C +CG       +LK HIRTHT ++ + C  C+ AF T G+L +HM      + 
Sbjct: 681  GEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRP 740

Query: 1810 -----CQETGVLEELEAEEGTSD---DLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDE 1861
                 CQ+T     L  ++       +L Q  +  + + ++++    D +   + + +  
Sbjct: 741  YMCPYCQKT-FKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTV-DQQSMQASTQMQV 798

Query: 1862 DEDEDEEESQDELSRPSSEAP-PPGPPHALRADSSPI---LGPQPPDAPASGTEATRGSS 1917
            + + DE     E+   + EA     P H +  + + +   L  QP +A   G  A +   
Sbjct: 799  EIESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPL 858

Query: 1918 VSEAERLTASSCSMSSQSMPGLP 1940
                ++    S +  S    GLP
Sbjct: 859  RGHVDQFEEQSPAQQSFEPAGLP 881



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 6/71 (8%)

Query: 172 SLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKT 231
           ++K T  AH K     K  K  CQYC +  +    L+ HIR HTG RP+ C  C   F+T
Sbjct: 520 AVKSTLTAHIKTHTGIKAFK--CQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRT 577

Query: 232 KSNLYKHRKSH 242
                 HRK+H
Sbjct: 578 SG----HRKTH 584



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 25/63 (39%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK- 1808
            G   Y C+ECG      S L  H++THT  + + C  C  AF TKG+L  HM+    +K 
Sbjct: 1191 GEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKP 1250

Query: 1809 -KC 1810
             KC
Sbjct: 1251 FKC 1253



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 1/59 (1%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK 1808
            G   + C ECG    +   L+ H+  HT  +P+ C  C  AF  KGNL  H++ + HS+
Sbjct: 221  GERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQ-RVHSE 278



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 20/50 (40%), Positives = 26/50 (52%)

Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKS 1803
            + C+ C         LK HIR HT VRP+ C HC   F+T G+   H+ S
Sbjct: 538  FKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIAS 587



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 21/53 (39%), Positives = 27/53 (50%)

Query: 1756 CEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK 1808
            C  C    KKPS L +H+R HT  +PY C  C  +F  K  L  H+K+    K
Sbjct: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQK 1221



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 21/49 (42%), Positives = 26/49 (53%)

Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMK 1802
            + C+ C     KPS L++H R HT  RP+ C  C  AF  K  L  HMK
Sbjct: 1722 FKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMK 1770



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 3/76 (3%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHS-- 1807
            G   + C  C     + S L+ H++ HT  RPY C +C   F  K N+  HMK +AHS  
Sbjct: 1746 GERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMK-RAHSYA 1804

Query: 1808 KKCQETGVLEELEAEE 1823
               QE+    E + EE
Sbjct: 1805 GALQESAGHPEQDGEE 1820



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 12/87 (13%)

Query: 167 RPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCG 226
           +PSQ++       H +    ++P K  C  C +   +   LQ H+  HTGE+P+ C  C 
Sbjct: 208 KPSQLT------RHIRIHTGERPFK--CSECGKAFNQKGALQTHMIKHTGEKPHACAFCP 259

Query: 227 FSFKTKSNLYKHRKSHAHRIKAGLASG 253
            +F  K NL    +SH  R+ + + +G
Sbjct: 260 AAFSQKGNL----QSHVQRVHSEVKNG 282



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 18/53 (33%), Positives = 25/53 (47%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMK 1802
            G+  + C  C         LK H+R HT  +P+ C HC   F+T G    HM+
Sbjct: 1219 GQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQ 1271



 Score = 45.1 bits (105), Expect = 9e-04
 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 2/71 (2%)

Query: 172  SLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKT 231
            ++K T + H K    QK   + C  CS   +    L+ H+R HTG +P+ C  C   F+T
Sbjct: 1205 TVKSTLDCHVKTHTGQK--LFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRT 1262

Query: 232  KSNLYKHRKSH 242
                  H + H
Sbjct: 1263 SGRRKTHMQFH 1273



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 2/63 (3%)

Query: 180  HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239
            H +    +KP  Y C  C +     S L  H+++HTG++ + C  C  +F TK +L  H 
Sbjct: 1185 HVRIHTGEKP--YKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHM 1242

Query: 240  KSH 242
            + H
Sbjct: 1243 RLH 1245



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 2/59 (3%)

Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK--KC 1810
            Y C  C    KK   LK+HIR+HT  +P+ C  C   F + G L  H+++    K  KC
Sbjct: 657  YKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKC 715



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 2/63 (3%)

Query: 180 HKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHR 239
           H +    +KP K  C  C R  A  S L  HI++HTG + + C  C  SF T  +L  H 
Sbjct: 500 HIRIHTHEKPFK--CPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHI 557

Query: 240 KSH 242
           + H
Sbjct: 558 RLH 560



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 16/49 (32%), Positives = 28/49 (57%)

Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMK 1802
            + C +C       S L  HI+THT ++ + C++C  +F T G+L  H++
Sbjct: 510  FKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIR 558



 Score = 40.0 bits (92), Expect = 0.028
 Identities = 16/49 (32%), Positives = 23/49 (46%)

Query: 1754 YVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMK 1802
            + C  C         L +H+ TH  ++PY C  C   F+T  +  KHMK
Sbjct: 1023 FSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMK 1071



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)

Query: 187 QKPGKYICQYCSRPCAKPSVLQKHIRSH-TGERPYPCGPCGFSFKTKSNLYKHRKSHA 243
           Q P  + C+ C     K S  Q+H+R H   ++P+ C  C  +F  + NL  H+ +H+
Sbjct: 32  QVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHS 89



 Score = 38.9 bits (89), Expect = 0.062
 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 18/83 (21%)

Query: 1750 GRGKYVCEECGIRCKKPSMLKKHIRTHTDVR----------------PYVCKHCHFAFKT 1793
            G  ++ C+ C    +  S LK+H++TH  +R                 Y C HC   F+ 
Sbjct: 149  GTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQK 208

Query: 1794 KGNLTKHMKSKAHSK--KCQETG 1814
               LT+H++     +  KC E G
Sbjct: 209  PSQLTRHIRIHTGERPFKCSECG 231



 Score = 37.4 bits (85), Expect = 0.18
 Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 4/53 (7%)

Query: 1755 VCEECGIRCKKPSMLKKHIRTHTD----VRPYVCKHCHFAFKTKGNLTKHMKS 1803
            +C ECG      S L  H+  H       R + CK C   F+T   L +HMK+
Sbjct: 122  ICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKT 174



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 10/75 (13%)

Query: 172 SLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSH----TGERPYPCGPCGF 227
           SLK     H+KE         IC  C       S L  H+  H     G R + C  C  
Sbjct: 107 SLKAHIMLHEKEEN------LICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKK 160

Query: 228 SFKTKSNLYKHRKSH 242
            F+T S L +H K+H
Sbjct: 161 EFETSSELKEHMKTH 175



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 15/53 (28%), Positives = 24/53 (45%)

Query: 194 CQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRI 246
           C  C++  ++ + L+ HI  H  E    C  CG  F  +S L  H + H   +
Sbjct: 95  CPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQEL 147



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 9/60 (15%)

Query: 1756 CEECGIRCKKPSMLKKHIRTH-TDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQETG 1814
            CE C +   K S  ++H+R H  + +P+ C  C   F  + NLT H        KC  +G
Sbjct: 39   CEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLH--------KCTHSG 90



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 15/37 (40%), Positives = 22/37 (59%), Gaps = 2/37 (5%)

Query: 1780 RPYVCKHCHFAFKTKGNLTKHMKSKAHSK--KCQETG 1814
            RPY C +CH A+K   +L +H++S    K  KC + G
Sbjct: 655  RPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCG 691



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 5/65 (7%)

Query: 1746 VRGRGRGKYVCEECGIRCKKPSMLKKHI-RTHTDVR---PYVCKHCHFAFKTKGNLTKHM 1801
            ++  G   + C  C     +   L+ H+ R H++V+    Y C  C   FK+ G+L  H+
Sbjct: 245  IKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHI 304

Query: 1802 KSKAH 1806
             SK H
Sbjct: 305  -SKMH 308



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 2/51 (3%)

Query: 1764 KKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSK--KCQE 1812
            KK   L   IR    VR +VC +C   F+   +L +H++   H K  KC +
Sbjct: 464  KKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQ 514


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 138/588 (23%), Positives = 201/588 (34%), Gaps = 67/588 (11%)

Query: 774  QPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPP 833
            QPR+  P S S++    +++   +S     SS   S+   + S       P  Q  S   
Sbjct: 403  QPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRG 462

Query: 834  APHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTL 893
            +P G S       L  + + Q+    V+    R    P PPP+           QR   +
Sbjct: 463  SPSGGSTAEASDTLSIRSSGQLSGRSVSL---RKLKRPPPPPRRTHSLH-----QRGLAV 514

Query: 894  AQLPAEKLPPKKKRLRLAEMAQ--SSGESSFESSVPLSRSPSQESNVSLS-GSSRSASFE 950
               P   LPPK +R +  ++ +  ++G S    + P   +P+      LS G SR     
Sbjct: 515  PDGPL-GLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSR----- 568

Query: 951  RDDHGKAEAPSPSS---------DMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSH 1001
            R         SPSS          + PK L     +     P   E  R  S +SP  S 
Sbjct: 569  RPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPE--RVTSLRSPGASV 626

Query: 1002 SAHMTETRSKSFDYGSLSLTGPSAPAPVAP----------PARVAPPERRKCFLVRQASL 1051
            S+ +T   S S D      +GP    P+            PA  +PP  +     R  + 
Sbjct: 627  SSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKP----RSPNP 682

Query: 1052 SRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPL 1111
            + P  +   V P     ++    S   P    +  Q S   +    PP    P    PP 
Sbjct: 683  AAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPP 742

Query: 1112 GPTVPYTEALQVFHHPVAQTPLHEKPYLPPP------------------VSLFSFQHLVQ 1153
                P            A+ PL +  + PPP                   + FS      
Sbjct: 743  PTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEP 802

Query: 1154 HEPGQSPEFFSTQAMSSLLSSPYSM-PPLPPSLFQAPPLPLQPTVLHPGQL-HLPQLMPH 1211
              P  SPE  S+ A SS  ++   + PP  P    APP P  P    PG +  LPQ  P 
Sbjct: 803  AGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAP-APASSAPGHVAKLPQKEPV 861

Query: 1212 PANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATG 1271
              +     P   +  P  T S L       + +      P  +    PQ     A     
Sbjct: 862  GCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPA-LGPSAPQKPLRRALSGRA 920

Query: 1272 SAGLSPSTEYSSDIRLPPVAPPAS---SSAPTSAPPLALPACPDTMVS 1316
            S   +PS+   + +RL   +  AS   SSA  + PP A P  P +  S
Sbjct: 921  SPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPAS 968



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 159/653 (24%), Positives = 218/653 (33%), Gaps = 132/653 (20%)

Query: 753  STKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSL 812
            ST S    S+  P  E  T      P P  GS  G     ++ E S          + S+
Sbjct: 430  STLSSKGGSEGQP--ESSTASNSVVPPPQGGSGRGSPSGGSTAEAS---------DTLSI 478

Query: 813  EQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQ--------------PKLVRQPNIQVPEI 858
                 L G    L +   PPP P  R  HSL               PK  R+   Q+P  
Sbjct: 479  RSSGQLSGRSVSLRKLKRPPPPP--RRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRP 536

Query: 859  LVTEEPDRPDTEPEPP------------------PKEPEKTEEFQWPQRSQT-------- 892
              T   +     P PP                  P+ PE+T        SQ+        
Sbjct: 537  PTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPK 596

Query: 893  -LAQLPA---EKLPPKKKRLRLAEMAQSSGESSFESSVPLSR--SPSQESNVSLSGSSRS 946
             LA  PA   +  PPK +R+       +S  SS  S    S   +PS  S   +  +   
Sbjct: 597  GLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQIL-TPLG 655

Query: 947  ASFERDDHGKAEAP---SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSA 1003
              F    H K  AP    PS    P P     L  P+  P       S ++ SP    + 
Sbjct: 656  DRFVIPPHPKVPAPFSPPPSKPRSPNPAAP-ALAAPAVVPGPV----STTDASPQSPPTP 710

Query: 1004 HMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSR---------- 1053
              T T  +     S   + P +P P   P    PP ++   +V   S S           
Sbjct: 711  QTTLTPLQESPVISKDQSPPPSPPPSYHPP--PPPTKKPEVVVEAPSASETAEEPLQDPN 768

Query: 1054 --------PPESELEVAPKGRQE-------SEEPQPSSSKPSAKSSLSQISSAATSHGGP 1098
                    P E +L +A     E       S EP   S  P   SS +  SS+AT+    
Sbjct: 769  WPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQ 828

Query: 1099 PGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHE-----KPYLPP------PVSLFS 1147
            P    PG   PP  P  P   +    H  VA+ P  E     K   PP      P+   S
Sbjct: 829  P----PGSPDPPPAPPAPAPASSAPGH--VAKLPQKEPVGCSKGGGPPREDVGAPLVTPS 882

Query: 1148 FQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLF-QAPPLPLQPTVLHPGQLHLP 1206
               +V+     +P    T A+    S+P    PL  +L  +A P+P   + LH       
Sbjct: 883  LLQMVRLRSVGAPGGAPTPALGP--SAPQK--PLRRALSGRASPVPAPSSGLHAAVRLKA 938

Query: 1207 QLMPHPANIPFRQP---PSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKT 1263
              +     +   QP   P   P P  + ++ +S  F     +  L+ P   E+     + 
Sbjct: 939  CSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRN 998

Query: 1264 SLAPLATGSAGLSPSTEYSSDIRLPPVA--------PPASSS----APTSAPP 1304
             +A L + S    P     S    PPVA        PPAS S     P +APP
Sbjct: 999  LVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPP 1051



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 148/605 (24%), Positives = 195/605 (32%), Gaps = 175/605 (28%)

Query: 1867 EEESQDELSRP--------SSEAP-PPGPPHALRADSSPILGPQPPDAPASGTEATRGSS 1917
            E + Q +L RP        +  AP PP P ++     SP    +PP +P           
Sbjct: 526  ERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSP----------- 574

Query: 1918 VSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKP---VSPRRPWS---- 1970
                ER  + S   SSQS  G P L P  L       G A   KP    S R P +    
Sbjct: 575  ----ERTLSPSSGYSSQS--GTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSS 628

Query: 1971 -------------PSKEAGSR--PPLARKHSLTKNDSSPQRCSPA----REPQASAPSPP 2011
                         PS  +G +   PL  +  +  +   P   SP     R P  +AP+  
Sbjct: 629  SLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALA 688

Query: 2012 GLHVDPG--RGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPT 2069
               V PG      A P   P  Q    TL PL       + V+SK +       P Y P 
Sbjct: 689  APAVVPGPVSTTDASPQSPPTPQT---TLTPL-----QESPVISKDQSPPPSPPPSYHP- 739

Query: 2070 RRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKL------ 2123
                      PP   PP K       +PSA E       DP    PP P P +       
Sbjct: 740  ----------PP---PPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMAD 786

Query: 2124 ------------------LSRSPETCASPWKAESRS-------------PSCSPGPAHPL 2152
                               S SPE  +SP  + S +             P   P PA P 
Sbjct: 787  FPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPA-PA 845

Query: 2153 SSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQAR----PGA 2208
            SS P        GH+    ++                  PL+    +QMV+ R    PG 
Sbjct: 846  SSAP--------GHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGG 897

Query: 2209 HPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSEL 2268
             PT   GP+A                R A   GR SP  + S+ +    ++   +L++  
Sbjct: 898  APTPALGPSAPQKP-----------LRRALS-GRASPVPAPSSGLHAAVRLKACSLAAS- 944

Query: 2269 EGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPD----------TLPRPP 2318
            EG         +   P  PP+         AEP P  SP +              L RP 
Sbjct: 945  EG--------LSSAQPNGPPE---------AEPRPPQSPASTASFIFSKGSRKLQLERPV 987

Query: 2319 --------QGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRN 2370
                    Q    A+  S   + P       P A PP+ R  SVG    AS  +P R   
Sbjct: 988  SPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYP-RAEP 1046

Query: 2371 LSGEP 2375
            L+  P
Sbjct: 1047 LTAPP 1051



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 134/526 (25%), Positives = 166/526 (31%), Gaps = 129/526 (24%)

Query: 1020 LTGPSAPA-PVAP---------------PARVAPPE-----RRKCFLVRQASLSRPPESE 1058
            LTG + PA P++P               P  V PP        +C L   +  S    S 
Sbjct: 328  LTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHSASP 387

Query: 1059 LEVAPKGRQES-EEPQPSSSKPSAKS---SLSQISSAATSHGG----------------- 1097
              V   GR  S   PQP S  PS+ S   S SQ S    S G                  
Sbjct: 388  ASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTA 447

Query: 1098 -----PPGGKGPGQDRPPLGPTVPYTEAL------QVFHHPVAQTPLHEKPYLPPPVSLF 1146
                 PP   G G+  P  G T   ++ L      Q+    V+   L   P  PPP    
Sbjct: 448  SNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPP--PPPRRTH 505

Query: 1147 SFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLP 1206
            S      H+ G +           +   P  +PP P    Q P LP  PT          
Sbjct: 506  SL-----HQRGLA-----------VPDGPLGLPPKPERK-QQPQLPRPPTTGGSEGAGAA 548

Query: 1207 QLMPHPAN--IP------FRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQ----LPGDV 1254
               P+PAN  +P       R+PP         SS  SS    P      L      PG  
Sbjct: 549  PCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKA 608

Query: 1255 ESHLPQ-----------IKTSLAPLATGSAGLSPSTEYSSDIRLP-------PVAP--PA 1294
            +   P+           + +SL  L + S+  +PS      I  P       P  P  PA
Sbjct: 609  QPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPA 668

Query: 1295 SSSAPTSAPPLALPACPDTMVSLVVPVRVQT-----NMPSYGSAMYTTLSQILVTQSQGS 1349
              S P S P    PA P      VVP  V T       P       T L +  V     S
Sbjct: 669  PFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQS 728

Query: 1350 SATVALPKFEEPP----SKGTTVCGADVHEVG----------PGPSGLSEEQSRA---FP 1392
                  P +  PP         V      E            P P    EEQ  +   FP
Sbjct: 729  PPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP 788

Query: 1393 TP-YLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGS 1437
             P      V  PE  G S S E + S   SSS+A   +  + P GS
Sbjct: 789  PPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQ--IQPPGS 832



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 124/531 (23%), Positives = 172/531 (32%), Gaps = 52/531 (9%)

Query: 1874 LSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSS 1933
            LSR S  +  P    +L   SS +  PQP     S +  T   S S ++ + +   ++SS
Sbjct: 377  LSRCSLHSASPASVRSLGRFSS-VSSPQPRSRHPSSSSDTWSHSQS-SDTIVSDGSTLSS 434

Query: 1934 QSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSP--SKEAGSRPPLARKHSLTKND 1991
            +             GS  +   S  S   V P +  S   S   GS    +   S+  + 
Sbjct: 435  KG------------GSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSG 482

Query: 1992 SSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELA----P 2047
                R    R+ +   P P   H    RG+ A+P G       PL L P          P
Sbjct: 483  QLSGRSVSLRKLKRPPPPPRRTHSLHQRGL-AVPDG-------PLGLPPKPERKQQPQLP 534

Query: 2048 RAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLG 2107
            R       EG      P  +P   W PG +    R  P        P S  + + G    
Sbjct: 535  RPPTTGGSEGAGAAPCPP-NPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPT- 592

Query: 2108 LDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHI 2167
            L P+ L  P   P K     PE   S     S   S S       SS    A  D  G  
Sbjct: 593  LPPKGLAGPPASPGKAQPPKPERVTS---LRSPGASVSSSLTSLCSSSSDPAPSDRSGPQ 649

Query: 2168 LARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGG 2227
            +     + F   P        +P P  P        A   A P ++PGP +   +     
Sbjct: 650  ILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPAL--AAPAVVPGPVSTTDASPQSP 707

Query: 2228 GSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRP 2287
             +  T     QE    S  +S   S  P                + P   E T   P + 
Sbjct: 708  PTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASE-TAEEPLQD 766

Query: 2288 PDWTPHGTGAPAEPTPTHSPCTPPDTL--------PRPPQGRR------AAQSWSPRLES 2333
            P+W P    AP E   + +   PP+          P  P G        AA S S     
Sbjct: 767  PNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQ 826

Query: 2334 PRAPTNPEPSATPPLDR--SSSVGCLAEASARFPARTRNLSGEPRTRQDSP 2382
             + P +P+P   PP     SS+ G +A+   + P       G PR    +P
Sbjct: 827  IQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAP 877



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 86/395 (21%), Positives = 129/395 (32%), Gaps = 68/395 (17%)

Query: 727  PPAFESTKSQFGSPGPSDAARNLPL----------ESTKSPAEPSKSV-PSLEGPTGFQP 775
            P  F    S+  SP P+  A   P            S +SP  P  ++ P  E P   + 
Sbjct: 667  PAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKD 726

Query: 776  RTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQ--------PSGLEGEDKPLAQ 827
            ++P P            T K   V++  S+ E ++   Q        P   E +D  +A 
Sbjct: 727  QSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMAD 786

Query: 828  FPSPP--------PAPHGRSAHSLQPKLVRQP--NIQVPEILVTEEPDRPDTEPEPPP-- 875
            FP P         P P G S     P+LV  P  +      L  + P  PD  P PP   
Sbjct: 787  FPPPEEAFFSVASPEPAGPSG---SPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPA 843

Query: 876  --------------KEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESS 921
                          KEP    +   P R    A L     P   + +RL  +    G  +
Sbjct: 844  PASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVT---PSLLQMVRLRSVGAPGGAPT 900

Query: 922  -----FESSVPLSRS--------PSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRP 968
                      PL R+        P+  S +  +   ++ S    +   +  P+   +  P
Sbjct: 901  PALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEP 960

Query: 969  KPLGTHMLTVP---SHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLS-LTGPS 1024
            +P  +   T     S      ++ R  S ++        + E RS S      +    P 
Sbjct: 961  RPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPK 1020

Query: 1025 APAPVAPPARVAPPERRKCFLVRQASLSRPPESEL 1059
            AP PVA    V  P        R   L+ PP + L
Sbjct: 1021 APPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGL 1055



 Score = 37.4 bits (85), Expect = 0.18
 Identities = 90/360 (25%), Positives = 123/360 (34%), Gaps = 75/360 (20%)

Query: 34   SVPYPGSGTAATQESPA-QELLAPQPFPGPSS------------VLREGSQEKTGQQQK- 79
            S P P +     QESP   +  +P P P PS             V+   S  +T ++   
Sbjct: 706  SPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQ 765

Query: 80   ----PPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVA 135
                PP  PP      +S     P   AF S   PE                GPSGS   
Sbjct: 766  DPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPE--------------PAGPSGS--- 808

Query: 136  PGL--HPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKP---QKPG 190
            P L   P +    + A  I P   P  P    P P+  S  P   A   +++P    K G
Sbjct: 809  PELVSSPAASSSSATALQIQPPGSPDPPPA-PPAPAPASSAPGHVAKLPQKEPVGCSKGG 867

Query: 191  KYICQYCSRPCAKPSVLQK-HIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAG 249
                +    P   PS+LQ   +RS       P    G S   K  L +     A  + A 
Sbjct: 868  GPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKP-LRRALSGRASPVPAP 926

Query: 250  LASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLS- 308
             +SG+   +      +                  SE  +SA    P E  PRP Q   S 
Sbjct: 927  -SSGLHAAVRLKACSL----------------AASEGLSSAQPNGPPEAEPRPPQSPAST 969

Query: 309  -SGLYSSGSHSSSHER-------CSLSQSSTAQ----SLEDPP--PFVEPSSEHPLSHKP 354
             S ++S GS     ER         L ++  A+    S + PP  P   P +  P++ KP
Sbjct: 970  ASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKP 1029



 Score = 37.4 bits (85), Expect = 0.18
 Identities = 63/255 (24%), Positives = 83/255 (32%), Gaps = 29/255 (11%)

Query: 1873 ELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSE--AERLTASSCS 1930
            ++  P S  PPP PP    A S+P    + P     G     G    +  A  +T S   
Sbjct: 826  QIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQ 885

Query: 1931 MSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKN 1990
            M      G P  G AP  ++          + +S R    P+  +G    +  K      
Sbjct: 886  MVRLRSVGAP--GGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAA 943

Query: 1991 DSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQL----SPLTLCPLGRELA 2046
                    P   P+A  P PP               GS +LQL    SP T   L R L 
Sbjct: 944  SEGLSSAQPNGPPEAE-PRPP--QSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLV 1000

Query: 2047 PRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGL 2106
                 +S+      P  P+ SP  +  P  A  P    PP       P SPS        
Sbjct: 1001 AELRSISE---QRPPQAPKKSP--KAPPPVARKPSVGVPP-------PASPSYPR----- 1043

Query: 2107 GLDPRVLFPPAPLPH 2121
              +P    P   LPH
Sbjct: 1044 -AEPLTAPPTNGLPH 1057


>gi|10047144 sal-like 4 [Homo sapiens]
          Length = 1053

 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 67/216 (31%), Positives = 92/216 (42%), Gaps = 55/216 (25%)

Query: 132 SFVAPGLHP------QSQLLPSHASIIPPEDLPGVP--------------------KVFV 165
           S ++PGL P       +++LP+  S +P   LP  P                    K   
Sbjct: 304 SSLSPGLAPFTLKPDGTRVLPNVMSRLPSALLPQAPGSVLFQSPFSTVALDTSKKGKGKP 363

Query: 166 PRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPC 225
           P  S V +KP +EA   + K        C+YCS+     S LQ H+RSHTGERP+ C  C
Sbjct: 364 PNISAVDVKPKDEAALYKHK--------CKYCSKVFGTDSSLQIHLRSHTGERPFVCSVC 415

Query: 226 GFSFKTKSNLYKHRKSHAHRIKAG----------LASGMGGEMYPHGLEMERIPGEEFEE 275
           G  F TK NL  H   H  ++KA           +A+G G    P+ L +     +  +E
Sbjct: 416 GHRFTTKGNLKVHFHRHP-QVKANPQLFAEFQDKVAAGNG---IPYALSVP----DPIDE 467

Query: 276 PTEGESTDSEEETSATS-GHPAELSPRPKQPLLSSG 310
           P+   S DS+     TS G P  LS       L+ G
Sbjct: 468 PS--LSLDSKPVLVTTSVGLPQNLSSGTNPKDLTGG 501



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 44/141 (31%), Positives = 64/141 (45%), Gaps = 10/141 (7%)

Query: 106 SPGKPEHLLEGSTWQ-LVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLP---GVP 161
           S G P++L  G+  + L     PG     + PG  P+S+  P+   + P  + P   G  
Sbjct: 482 SVGLPQNLSSGTNPKDLTGGSLPGD----LQPGPSPESEGGPTLPGVGPNYNSPRAGGFQ 537

Query: 162 KVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYP 221
               P P   +LK  +     ++    P +  C  C R  +  S L+ H R+HTGERP+ 
Sbjct: 538 GSGTPEPGSETLKLQQLVENIDKATTDPNE--CLICHRVLSCQSSLKMHYRTHTGERPFQ 595

Query: 222 CGPCGFSFKTKSNLYKHRKSH 242
           C  CG +F TK NL  H   H
Sbjct: 596 CKICGRAFSTKGNLKTHLGVH 616



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 37/99 (37%), Positives = 50/99 (50%), Gaps = 4/99 (4%)

Query: 145 LPSHASIIPPEDLP-GVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAK 203
           LPS     PP  +   VP  FV  PS +S   T     + R+  K  ++ C  C +  + 
Sbjct: 825 LPSTFIRAPPTYVKVEVPGTFVG-PSTLSPGMTPLLAAQPRRQAK--QHGCTRCGKNFSS 881

Query: 204 PSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242
            S LQ H R+HTGE+P+ C  CG +F TK NL  H  +H
Sbjct: 882 ASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVHYMTH 920



 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 76/310 (24%), Positives = 111/310 (35%), Gaps = 66/310 (21%)

Query: 1767 SMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHM---------KSKAHSKKCQET---- 1813
            S LK H RTHT  RP+ CK C  AF TKGNL  H+         K++     CQ+     
Sbjct: 579  SSLKMHYRTHTGERPFQCKICGRAFSTKGNLKTHLGVHRTNTSIKTQHSCPICQKKFTNA 638

Query: 1814 ------------GVLEELEAEEGTSDDLFQDSE----GREGSEAVEEHQFSDLEDSDSDS 1857
                        G +      E   D  F  SE    G  GS     H     +D     
Sbjct: 639  VMLQQHIRMHMGGQIPNTPLPENPCD--FTGSEPMTVGENGSTGAICH-----DDVIESI 691

Query: 1858 DLDEDEDEDEEESQDELSRP----SSEAPPPGPPHALRADSSPILGPQPPDAPASGTEAT 1913
            D++E   ++   S  ++  P     S +P  G       D+   +GP P +    G   +
Sbjct: 692  DVEEVSSQEAPSSSSKVPTPLPSIHSASPTLGFAMMASLDAPGKVGPAPFNLQRQG---S 748

Query: 1914 RGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSK 1973
            R +   E++ LT  S S+          +G     S   D     S++ +SP    S ++
Sbjct: 749  RENGSVESDGLTNDSSSL----------MGDQEYQSRSPDILETTSFQALSPAN--SQAE 796

Query: 1974 EAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSP--------PGLHVDPGR---GMG 2022
               S+ P A   + +  +S  +    +  P     +P        PG  V P     GM 
Sbjct: 797  SIKSKSPDAGSKAESSENSRTEMEGRSSLPSTFIRAPPTYVKVEVPGTFVGPSTLSPGMT 856

Query: 2023 ALPCGSPRLQ 2032
             L    PR Q
Sbjct: 857  PLLAAQPRRQ 866



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 50/177 (28%), Positives = 71/177 (40%), Gaps = 40/177 (22%)

Query: 1646 AALSLLRSK---QKVSKETYTMATAPHPEAGRLVPSSSR-------KPRMTEV------H 1689
            AA++LL  K   Q +S +    A  PH        S S        KP  T V       
Sbjct: 270  AAVALLSQKAGSQGLSLDALKQAKLPHANIPSATSSLSPGLAPFTLKPDGTRVLPNVMSR 329

Query: 1690 LPSLVSPEG------QKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSNEEY 1743
            LPS + P+       Q   + V  +  ++G          +G+P  I   +   K +E  
Sbjct: 330  LPSALLPQAPGSVLFQSPFSTVALDTSKKG----------KGKPPNISAVDVKPK-DEAA 378

Query: 1744 VYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800
            +Y       K+ C+ C       S L+ H+R+HT  RP+VC  C   F TKGNL  H
Sbjct: 379  LY-------KHKCKYCSKVFGTDSSLQIHLRSHTGERPFVCSVCGHRFTTKGNLKVH 428



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 22/45 (48%), Positives = 25/45 (55%)

Query: 1756 CEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800
            C  CG      S L+ H RTHT  +P+VC  C  AF TKGNL  H
Sbjct: 872  CTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVH 916



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 54/236 (22%), Positives = 84/236 (35%), Gaps = 49/236 (20%)

Query: 191 KYICQYCSRPCAKPSVLQKHIRSHTG----ERPYPCGPCGFSFKTKSNLYKHRKSHAHRI 246
           ++ C  C +      +LQ+HIR H G      P P  PC F+      + ++        
Sbjct: 625 QHSCPICQKKFTNAVMLQQHIRMHMGGQIPNTPLPENPCDFTGSEPMTVGEN-------- 676

Query: 247 KAGLASGMGGEMYPHGLEMERI-----PGEEFEEPTEGESTDSEEET-----SATSGHPA 296
             G    +  +     +++E +     P    + PT   S  S   T      A+   P 
Sbjct: 677 --GSTGAICHDDVIESIDVEEVSSQEAPSSSSKVPTPLPSIHSASPTLGFAMMASLDAPG 734

Query: 297 ELSPRPKQPLLSSGLYSSGSHSS---SHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHK 353
           ++ P P   L   G   +GS  S   +++  SL      QS    P  +E +S   LS  
Sbjct: 735 KVGPAPFN-LQRQGSRENGSVESDGLTNDSSSLMGDQEYQSRS--PDILETTSFQALSPA 791

Query: 354 PEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNT 409
                +IK K                  SP +    ES   SR+E  E + S P+T
Sbjct: 792 NSQAESIKSK------------------SPDAGSKAESSENSRTE-MEGRSSLPST 828


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 296/1379 (21%), Positives = 446/1379 (32%), Gaps = 196/1379 (14%)

Query: 276  PTEGESTDSEEETSATSGHPAELSPR----PKQPLLSS-GLYSSGSHSSSHERCSLSQSS 330
            P+   ST S     +T+ H +  S +    P+    S  G  S+ SHSS+    S + S+
Sbjct: 3455 PSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPST 3514

Query: 331  TAQSLEDPPPFVEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTE 390
            T+  +E+P  +         +H P+ + T  +      S   +       L   S  S  
Sbjct: 3515 TSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVL 3574

Query: 391  SGYFSRSE----SAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTE 446
             G  + S     S E    P +T     +E                T   + P  P +T 
Sbjct: 3575 LGESTTSPISSGSMETTALPGSTTTPGLSE--------------KSTTFHSSPRSPATTL 3620

Query: 447  DKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLYR 506
               S     V       H     T   A  D++    +   R S +  SS  S  ++L  
Sbjct: 3621 SPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLS--RHSTTSHSSPGSTDTTLL- 3677

Query: 507  EPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHHPFRGSYS---F 563
             P S+ +  +  E    +  H  S +    L    +   +    ST  H   GS     F
Sbjct: 3678 -PASTTTSGSSQES---TTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF 3733

Query: 564  DDHITDSEALSHSS--HVFTSHPRMLKRQPAIELP-LGGEYSSEEPGPSSKDTA-SKPSD 619
             D  T S  +  S+  H  T  PR      +   P L GE ++ +  P+S  T  S PS 
Sbjct: 3734 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPST 3793

Query: 620  EVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKPISAGT 679
               P E   T     G          +      +K   + +       +     P SA +
Sbjct: 3794 ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS-----SPDASGTTPSSAHS 3848

Query: 680  HTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFESTKS--QF 737
             TS   E +     P S  +    G+T   TP               P    S  S    
Sbjct: 3849 TTSGRGESTTSRISPGSTEITTLPGST--TTPGLSEASTTFYSSPRSPTTTLSPASMTSL 3906

Query: 738  GSPGPSDAARNLP--LESTKSPAEPSKSVPSLEGPT------GFQPRTPKPGSGSES-GK 788
            G    S  +R+ P    ST SPA  +    S E  T      G    T  P S + S  +
Sbjct: 3907 GVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRR 3966

Query: 789  ERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLV 848
            E  TT        HT+ F +  +    SGL  E      FP  P +              
Sbjct: 3967 EEPTTFHSRPASTHTTLFTEDST---TSGLTEES---TAFPGSPAS-------------- 4006

Query: 849  RQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRL 908
                  +P  L T +     T     P     T     P RS T + L  E  P      
Sbjct: 4007 --TQTGLPATLTTADLGEEST---TFPSSSGSTGTKLSPARS-TTSGLVGESTP------ 4054

Query: 909  RLAEMAQSSGESSFESSVPLSRSPSQESNV-SLSGSSRSASFERDDHGKAEAPSPSSDMR 967
              + ++ SS E++     P + S S++S     S  S  A+        +     SS   
Sbjct: 4055 --SRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSH 4112

Query: 968  PKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHS------AHMTETRSKSFDYGSLSLT 1021
             +P  TH    P           S   Q P  SHS      A ++   + +   G  S T
Sbjct: 4113 SQPGSTHTTAFPD------STTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTT 4166

Query: 1022 GPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELE--VAPKGRQESEEPQPSSSKP 1079
              S+P        + P +     LV  ++ +      L   + P     +   + S++  
Sbjct: 4167 FHSSPGDT--ETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQ 4224

Query: 1080 SAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYL 1139
            S  SS     S  ++   P         RP   PT  ++ +          T +H  P  
Sbjct: 4225 SWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP-- 4282

Query: 1140 PPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLH 1199
                                   F T++ +S+L    +  P+     +   LP   T   
Sbjct: 4283 ----------------GATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT-- 4324

Query: 1200 PGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLP 1259
                 L +      + P R P + L     TSS +S       +S  +   PG + +   
Sbjct: 4325 ---AGLSEKSTTFYSSP-RSPDTTLSPASTTSSGVSE------ESTTSHSRPGSMHTTAF 4374

Query: 1260 QIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDT------ 1313
               T++ P  +  +  S S+  S+D  L P +  ASS  P S    + P   +T      
Sbjct: 4375 PSSTTM-PGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDN 4433

Query: 1314 -----MVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTV 1368
                 ++    PV   T  P      +TTLS    T  QG S T        P SK TT 
Sbjct: 4434 TTASGLLEASTPVHSSTGSP------HTTLSPAGSTTRQGESTTFQ----SWPNSKDTT- 4482

Query: 1369 CGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGS 1428
                     P P       + AF        V L      S SS        SS+T G S
Sbjct: 4483 ---------PAP----PTTTSAF--------VELSTTSHGSPSSTPTTHFSASSTTLGRS 4521

Query: 1429 KRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGN 1488
            +   +   S   T  T    R      S     +E          ST+    PE +    
Sbjct: 4522 EESTTVHSSPVATATTPSPAR------STTSGLVEESTTYHSSPGSTQTMHFPESNTTSG 4575

Query: 1489 QGQ--GRRELEMLSSLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGL 1546
            +G+           ++SS PS T  +   P    S+ ++PGS A   +P  S    R   
Sbjct: 4576 RGEESTTSHSSTTHTISSAPSTTSALVEEP---TSYHSSPGSTATTHFPDSSTTSGRSEE 4632

Query: 1547 TPLSVKKEDSKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVS 1605
            +  S   +D+     LP+ +  S L L E+++ P  S     S +    P   TT  +S
Sbjct: 4633 STASHSSQDATGTIVLPARSTTSVL-LGESTTSPISS----GSMETTALPGSTTTPGLS 4686



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 385/1776 (21%), Positives = 570/1776 (32%), Gaps = 311/1776 (17%)

Query: 729  AFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPT--------GFQPRTPKP 780
            AF  + +  G    S A+ ++P  ST +   P  + PS  GP         G+   T  P
Sbjct: 322  AFPDSTTMPGVSQESTASHSIP-GSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLP 380

Query: 781  GSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPP---PAPHG 837
             + + SG    +T    S     ++   S S       EGE      +PS     PAP G
Sbjct: 381  DNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTH----EGEPTTFQSWPSSKDTSPAPSG 436

Query: 838  RSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKT---EEFQWPQRSQTLA 894
             ++  ++              L T     P + P         T    E   P  S  +A
Sbjct: 437  TTSAFVK--------------LSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVA 482

Query: 895  QLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQ-------ESNVSLSGSSRSA 947
               A   PP          A+S+     E S    RSP         ES+ +   S  SA
Sbjct: 483  T--ATTPPP----------ARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESA 530

Query: 948  SFERDD-HGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAH-- 1004
            +F     H K+  PS ++ +      + + +  + H          SE+S   SHS+   
Sbjct: 531  TFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEES-KASHSSPDA 589

Query: 1005 MTETRSKSFDYGSLSLTGPSAPAPV--------APPARVAPPERRKCFLVRQASLSRPPE 1056
            M  T   +    S+ L G S P+P+        A P     P   +      +S   P  
Sbjct: 590  MATTVLPAGSTPSV-LVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDT 648

Query: 1057 SELEVAPKGRQESEEPQPSSSKPSAKSS-----------LSQISSAATSHGGPPGGK-GP 1104
            + L  +      SEE   S S+P +  +           LSQ S+A+ S  GP      P
Sbjct: 649  THLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSP 708

Query: 1105 GQDRPP-LGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQH--LVQHEPGQSPE 1161
            G      LGP   YT     FH     T   E   LP   +        +  H   +SP 
Sbjct: 709  GSTTASSLGPE--YT----TFHSRPGST---ETTLLPDNTTASGLLEASMPVHSSTRSPH 759

Query: 1162 FFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPP 1221
               + A S+      +     PS     P P   T         P    H +       P
Sbjct: 760  TTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTT----SAFVEPSTTSHGS-------P 808

Query: 1222 SFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVES-HLPQIKT----------------- 1263
            S +P  + ++ + +SG  L  +S      PG  ++ H P+  T                 
Sbjct: 809  SSIPTTHISARSTTSG--LVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTH 866

Query: 1264 --SLAPLATGSAGLSPSTEYSSDIRLPPVA-PPASSSAPTSAPPLALPACPDTMVSLVVP 1320
              S AP  T +    P++ +SS         P +S+++  S    A  +  D   ++V+P
Sbjct: 867  TISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 926

Query: 1321 VRVQTNMPSYGSAMYTTLSQ--ILVTQSQGSSATVALPK-----FEEPPSKGTTVCGADV 1373
             R  T++   G +  + +S   +  T   GS+ T  L +        P S  TT+  A  
Sbjct: 927  ARSTTSV-LLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPAST 985

Query: 1374 HEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGT-SLSSESILSLEGSSSTAGGSKRVL 1432
                   SG+SEE + +   P        P+   T  LS  S  S     S+ G +   L
Sbjct: 986  TS-----SGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTS----HSSPGSTDTTL 1036

Query: 1433 SPAGSLELTMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQG 1492
             PA +   T    Q+       +   D  L    P S   T+   G+     H  N G  
Sbjct: 1037 LPASTT--TSGPSQESTTSHSSSGSTDTALS---PGST--TALSFGQESTTFH-SNPGST 1088

Query: 1493 RRELEMLSSLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRG-LTPLSV 1551
               L   S+ SS          +   +    ++ GS      P  S  P  +G  T    
Sbjct: 1089 HTTLFPDSTTSSG---------IVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQT 1139

Query: 1552 KKEDSKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNY 1611
                +   P  PS A   + P+ E+++          S     FP+  TT+  S      
Sbjct: 1140 HPASTHTTPSPPSTA---TAPVEESTTY----HRSPGSTPTTHFPASSTTSGHS------ 1186

Query: 1612 IKPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPE 1671
             + + I H+   +S   G   S  +    G        +     +++    +  T    E
Sbjct: 1187 -EKSTIFHSSPDAS---GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSE 1242

Query: 1672 AGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIK 1731
            A     SS R P  T       +SP     L   E+    R +P      S     +   
Sbjct: 1243 ASTTFYSSPRSPTTT-------LSPASMTSLGVGEESTTSRSQP-----GSTHSTVSPAS 1290

Query: 1732 IFEGGYKSNEEYVYVRGRGRGKYVC----EECGIRCKKPSML-KKHIRTHTDVRPYVCKH 1786
                G       VY   RG  +           +  ++P+    +   THT +       
Sbjct: 1291 TTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTL------- 1343

Query: 1787 CHFAFKTKGNLTKHMKSKAHSKKCQETGVLEELE-AEEGTSDDLFQDSEGREGSEAVEEH 1845
                  T   LT+   +   S    +TG+   L  A+ G     F  S G  G++     
Sbjct: 1344 -FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTK----- 1397

Query: 1846 QFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDA 1905
              S    + S    +         S +  + P S    P  P      ++    P+ PDA
Sbjct: 1398 -LSPARSTTSGLVGESTPSRLSPSSTETTTLPGS----PTTPSLSEKSTTFYTSPRSPDA 1452

Query: 1906 PASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSP 1965
              S    T  S VSE         S +S S PG       P    +  T S LS +P + 
Sbjct: 1453 TLSPATTT-SSGVSEE--------SSTSHSQPGSTHTTAFP----DSTTTSDLSQEPTTS 1499

Query: 1966 RRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALP 2025
                  S EA   P      SL +  S+    SP        P      +  G    + P
Sbjct: 1500 HSSQG-STEATLSPGSTTASSLGQQ-STTFHSSPGDTETTLLPDDT---ITSGLVEASTP 1554

Query: 2026 CGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESP----- 2080
              S    L   TL P     A         E TT    P  S T    PG   +P     
Sbjct: 1555 THSSTGSLHT-TLTPASSTSAGLQE-----ESTTFQSWPSSSDTTPSPPGTTAAPVEVST 1608

Query: 2081 -----PRSAPPGKWALA----GPGSPSAGEHGPGLGLDPRVLFPPA---------PLPHK 2122
                 P S P   ++ +    G    S   H    G     LFP           P    
Sbjct: 1609 TYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP-GATGTALFPTRSATSVLVGEPTTSP 1667

Query: 2123 LLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLH 2182
            + S S ET A P    +   S      +     P + L          +EE+  SH    
Sbjct: 1668 ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPG 1727

Query: 2183 SQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLT----GAREAQ 2238
            S H T                A PG+  T +PG +    +  S  GS  T    G+  A 
Sbjct: 1728 STHTT----------------AFPGS--TTMPGVSQESTASHSSPGSTDTTLSPGSTTAS 1769

Query: 2239 ERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAP 2298
              G  S T  SS   +    +   T +S L     P     TG         +PH T +P
Sbjct: 1770 SLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSS-TG---------SPHTTLSP 1819

Query: 2299 A-------EPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRS 2351
            A       E T   S  +  DT+P PP    A    S         ++  PS+TP    S
Sbjct: 1820 AGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELS-------TTSHGSPSSTPTTHFS 1872

Query: 2352 SSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGS 2387
            +S   L  +       +  +   P     +P P+ S
Sbjct: 1873 ASSTTLGRSE-----ESTTVHSSPVATATTPSPARS 1903



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 282/1339 (21%), Positives = 452/1339 (33%), Gaps = 189/1339 (14%)

Query: 310  GLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTIKQKLALRLS 369
            G  S+ SHSS+    S + S+T+  +E+P  +         +H P+ + T  +       
Sbjct: 854  GEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR------- 906

Query: 370  ERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRT 429
                   E++  S  S+ +T +       +    +    T+  S   +         + T
Sbjct: 907  ------SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM---------ETT 951

Query: 430  AMLTATSTQPLLPLST-------EDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEID 482
            A+  +T+T  L   ST           +L P S   + V E  T   +   +   T+  D
Sbjct: 952  ALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPD 1011

Query: 483  SVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHS 542
            S      S    +S  SP S+     L   S  T       +  H  S +    L    +
Sbjct: 1012 STTTPGLSRHSTTSHSSPGST--DTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGST 1069

Query: 543  MPSAACTISTPHHPFRGSYS---FDDHITDSEALSHSS--HVFTSHPRMLKRQPAIELP- 596
               +    ST  H   GS     F D  T S  +  S+  H  T  PR      +   P 
Sbjct: 1070 TALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG 1129

Query: 597  LGGEYSSEEPGPSSKDTA-SKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKR 655
            L GE ++ +  P+S  T  S PS    P E   T     G  T    +  +   + + ++
Sbjct: 1130 LQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG-STPTTHFPASSTTSGHSEK 1188

Query: 656  DNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKR 715
                       S +  + P ++G  T+P +  S       S       G+T E+T L   
Sbjct: 1189 -----------STIFHSSPDASG--TTPSSAHSTTSGRGESTTSRISPGST-EITTLPGS 1234

Query: 716  RKEKSLGDEEEPPAFESTKSQFGSPGP-SDAARNLPLESTKSPAEPSKSVPSLEGPTGFQ 774
                 L  E     + S +S   +  P S  +  +  EST S ++P  S  S   P    
Sbjct: 1235 TTTPGL-SEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG-STHSTVSPAS-- 1290

Query: 775  PRTPKPGSGSESGKERRTT--SKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPP 832
              T  PG   ES     ++  S E +V  H+++          + + GE+         P
Sbjct: 1291 --TTTPGLSEESTTVYSSSRGSTETTVFPHSTT----------TSVHGEE---------P 1329

Query: 833  PAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQT 892
               H R A +                  T  P  P +     P      +  +      +
Sbjct: 1330 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS 1389

Query: 893  LAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERD 952
             +     KL P          A+S+       S P   SPS     +L GS  + S    
Sbjct: 1390 SSGSTGTKLSP----------ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEK 1439

Query: 953  DHGKAEAP-SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSK 1011
                  +P SP + + P    +  ++  S          S S   P  +H+    ++ + 
Sbjct: 1440 STTFYTSPRSPDATLSPATTTSSGVSEES----------STSHSQPGSTHTTAFPDSTTT 1489

Query: 1012 SFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASL--SRPPESELEVAPKGRQES 1069
            S D      T  S+    +  A ++P       L +Q++   S P ++E  + P     S
Sbjct: 1490 S-DLSQEPTTSHSSQG--STEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITS 1546

Query: 1070 EEPQPSSSKPSAKSSL-SQISSAATSHGGPPGGKGPGQDRP--------PLGPTVPYTEA 1120
               + S+   S+  SL + ++ A+++  G        Q  P        P G T    E 
Sbjct: 1547 GLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEV 1606

Query: 1121 LQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQS-PEFFSTQAMSSLLSSPYSMP 1179
               +H   + TP          +        V   PG +    F T++ +S+L    +  
Sbjct: 1607 STTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTS 1666

Query: 1180 PLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFF 1239
            P+     +   LP   T        L +      + P R P + L     TSS +S    
Sbjct: 1667 PISSGSTETTALPGSTTT-----AGLSEKSTTFYSSP-RSPDTTLSPASTTSSGVSE--- 1717

Query: 1240 LPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAP 1299
               +S  +   PG   +      T++ P  +  +  S S+  S+D  L P +  ASS  P
Sbjct: 1718 ---ESTTSHSRPGSTHTTAFPGSTTM-PGVSQESTASHSSPGSTDTTLSPGSTTASSLGP 1773

Query: 1300 TSAPPLALPACPDT-----------MVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQG 1348
             S    + P   +T           ++    PV   T  P      +TTLS    T  QG
Sbjct: 1774 ESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSP------HTTLSPAGSTTRQG 1827

Query: 1349 SSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGT 1408
             S T     F+  PS   T+         P P       + AF        V L      
Sbjct: 1828 ESTT-----FQSWPSSKDTM---------PAP----PTTTSAF--------VELSTTSHG 1861

Query: 1409 SLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPC 1468
            S SS        SS+T G S+   +   S   T  T    R      S     +E     
Sbjct: 1862 SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPAR------STTSGLVEESTAY 1915

Query: 1469 SVVLTSTEDGKRPEKSHLGNQGQGRR--ELEMLSSLSSDPSDTKEIPPLPHPALSHGTAP 1526
                 ST+    PE S    + +  R        ++SS PS T  +   P    S+ ++P
Sbjct: 1916 HSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEP---TSYHSSP 1972

Query: 1527 GSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSSLPLSETSSRPAKSQEG 1586
            GS A   +P  S    R   +  S   +D+     LP+ +  S L L E+++ P  S   
Sbjct: 1973 GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVL-LGESTTSPISS--- 2028

Query: 1587 TDSKKVLQFPSLHTTTNVS 1605
              S +    P   TT  +S
Sbjct: 2029 -GSMETTALPGSTTTPGLS 2046



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 357/1703 (20%), Positives = 516/1703 (30%), Gaps = 317/1703 (18%)

Query: 6    SVKGTKKAEGSPRKRLTKG-------EAIQTSVSSSVPYPGSGTAATQESPAQELL---- 54
            S  G+   + SP +  T G         +  S + +   PGS T  +    +        
Sbjct: 1389 SSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPR 1448

Query: 55   APQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLL 114
            +P     P++    G  E++      P       S H +  P    T          H  
Sbjct: 1449 SPDATLSPATTTSSGVSEESSTSHSQP------GSTHTTAFPDSTTTSDLSQEPTTSHSS 1502

Query: 115  EGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPS-----HASIIPPEDLP-GVPKVFVPRP 168
            +GST   + P      GS  A  L  QS    S       +++P + +  G+ +   P  
Sbjct: 1503 QGSTEATLSP------GSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTH 1556

Query: 169  SQV-SLKPT-EEAHKKERKPQKPGKYICQYCSRPCAKPS-----VLQKHIRSHTGERPYP 221
            S   SL  T   A       Q+       + S     PS          + +    RP  
Sbjct: 1557 SSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSS 1616

Query: 222  CGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGES 281
                 FS  + + L +  +S       G     G  ++P       + GE    P    S
Sbjct: 1617 TPTTHFS-ASSTTLGRSEESTTVHSSPGAT---GTALFPTRSATSVLVGEPTTSPISSGS 1672

Query: 282  TDSEEETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPF 341
            T    ET+A  G         K    S+  YSS   S        S +S+  S E     
Sbjct: 1673 T----ETTALPGSTTTAGLSEK----STTFYSS-PRSPDTTLSPASTTSSGVSEESTTSH 1723

Query: 342  VEPSSEHPLSHKPEDTHT-IKQKLALRLSERKKVIDEQAFLSPGSKGSTESG-----YFS 395
              P S H  +     T   + Q+     S           LSPGS  ++  G     + S
Sbjct: 1724 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPGST---DTTLSPGSTTASSLGPESTTFHS 1780

Query: 396  RSESAEQQVSPPNTNAKSYAEIIF----------------GKCGRIGQRTAMLTATSTQP 439
               S E  + P NT A    E                   G   R G+ T   +  S++ 
Sbjct: 1781 SPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKD 1840

Query: 440  LLPLSTEDKPSLV---------PLSVPRTQVIEHITKL------ITINEAVVDTSEIDSV 484
             +P       + V         P S P T      T L       T++ + V T+   S 
Sbjct: 1841 TMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS- 1899

Query: 485  KPRRSSLSR--------RSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVP 536
             P RS+ S          SS  S ++  + E  ++     +   S  S  H  S+ P   
Sbjct: 1900 -PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPP--- 1955

Query: 537  LLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELP 596
                 S  SA     T +H   GS +   H  DS   S  S   T+          I LP
Sbjct: 1956 -----STTSALVEEPTSYHSSPGSTA-TTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 2009

Query: 597  -------LGGEYSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICG 649
                   L GE ++      S +T + P     P           GL  K   +      
Sbjct: 2010 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTP-----------GLSEKSTTFH----- 2053

Query: 650  ARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLEL 709
                                  + P S  T  SP +  S    E  S   H + G+T   
Sbjct: 2054 ----------------------SSPRSPATTLSPASTTSSGVSEE-STTSHSRPGST--- 2087

Query: 710  TPLRKRRKEKSLGDEEEPPAFES-TKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLE 768
                      +  D    P     + +   SPG +D        +T  P++ S +  S  
Sbjct: 2088 -------HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSP 2140

Query: 769  GPTGFQPRTPKPGSGSE-SGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQ 827
            G T        PGS +  S  +  TT        HT+ F   DS      +E   +  + 
Sbjct: 2141 GSTD---TALSPGSTTALSFGQESTTFHSSPGSTHTTLFP--DSTTSSGIVEASTRVHSS 2195

Query: 828  FPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWP 887
              SP          +L P     P +Q         P    T P PP       EE    
Sbjct: 2196 TGSPRT--------TLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTY 2247

Query: 888  QRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSA 947
             RS      P    P           A S+     E S     SP        SG++ S+
Sbjct: 2248 HRSP--GSTPTTHFP-----------ASSTTSGHSEKSTIFHSSP------DASGTTPSS 2288

Query: 948  SFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTE 1007
            +     H        S+  R  P  T + T+P           S +  S   S +  ++ 
Sbjct: 2289 A-----HSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSP 2343

Query: 1008 TRSKSFDYGSLSLTGPSAP----APVAPPARVAPPERRKCFLVRQASLSRPPESELEVAP 1063
                S   G  S T  S P    + V+P +   P    +   V  +S   P  +E  V P
Sbjct: 2344 ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSS---PGSTETTVFP 2400

Query: 1064 KGRQES---EEPQPSSSKPSA--------KSSLSQISSAATSHGGPPGGKGPGQDRPPLG 1112
            +    S   EEP    S+P++         S+ S ++  +T+  G P     G   P   
Sbjct: 2401 RTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG--LPATL 2458

Query: 1113 PTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLL 1172
             T    E    F      T     P                            ++ +S L
Sbjct: 2459 TTADLGEESTTFPSSSGSTGTTLSP---------------------------ARSTTSGL 2491

Query: 1173 SSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANI--PFRQPPSFLPMPYPT 1230
                +   L PS  +   LP  PT         P L           R P + L     T
Sbjct: 2492 VGESTPSRLSPSSTETTTLPGSPTT--------PSLSEKSTTFYTSPRSPDATLSPATTT 2543

Query: 1231 SSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPV 1290
            SS +S       +S  +   PG   +      T+   L+  S   S S+  S+D  L P 
Sbjct: 2544 SSGVSE------ESSTSHSQPGSTHTTAFPDSTTTPGLSRHST-TSHSSPGSTDTTLLPA 2596

Query: 1291 APPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSS 1350
            +   S  +  S    + P   DT +S        T   S+G    T  S      S GS+
Sbjct: 2597 STTTSGPSQESTTSHSSPGSTDTALS-----PGSTTALSFGQESTTFHS------SPGST 2645

Query: 1351 ATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPV--TLPERKGT 1408
             T   P  +   S G       VH     P       S   P          T P    T
Sbjct: 2646 HTTLFP--DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHT 2703

Query: 1409 SLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPC 1468
            + S  S  +     ST        +P      +  T           S   EK       
Sbjct: 2704 TPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTT-----------SGHSEK------- 2745

Query: 1469 SVVLTSTED--GKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALSHGTAP 1526
            S +  S+ D  G  P  +H    G+G      +S     P  T EI  LP    + G + 
Sbjct: 2746 STIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS-----PGST-EITTLPGSTTTPGLSE 2799

Query: 1527 GSEALKEYPQ-PSGKPHRRGLTPLSVKKED--SKEQP-DLPSLAPPSSLP---LSETSSR 1579
             S      P+ P+       +T L V +E   S+ QP    S   P+S     LSE S+ 
Sbjct: 2800 ASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTT 2859

Query: 1580 PAKSQEGTDSKKVLQFPSLHTTT 1602
               S  G+    V  FP   TT+
Sbjct: 2860 VYSSSPGSTETTV--FPRSTTTS 2880



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 299/1432 (20%), Positives = 448/1432 (31%), Gaps = 197/1432 (13%)

Query: 279  GESTDSEEETSATSGHPAELSPRPK-QPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLED 337
            G +T       +T+ H +  SP     P  ++    S   ++SH R   + ++       
Sbjct: 3595 GSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTT 3654

Query: 338  PPPFVEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAF------LSPGSK----- 386
             P     S+    S    DT  +        S ++      +       LSPGS      
Sbjct: 3655 TPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSF 3714

Query: 387  GSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQ-RTAMLTATSTQPLL---- 441
            G   + + S   S    + P +T +    E         G  RT +  A+ST P L    
Sbjct: 3715 GQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 3774

Query: 442  ------PLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRS 495
                  P ST   PS  P S          T    + E+        S        S  +
Sbjct: 3775 TAFQTHPASTHTTPS--PPS----------TATAPVEESTTYHRSPGSTPTTHFPASSTT 3822

Query: 496  SMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHH 555
            S  S KS+++          + P+ S  +    PS+A      R  S  S     ST   
Sbjct: 3823 SGHSEKSTIFH---------SSPDASGTT----PSSAHSTTSGRGESTTSRISPGSTEIT 3869

Query: 556  PFRGSYSFDDHITDSEALSHSSHVFTSHPRM----LKRQPAIELPLGGEYSSEEPGPSSK 611
               GS       T +  LS +S  F S PR     L       L +G E ++    P S 
Sbjct: 3870 TLPGS-------TTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGST 3922

Query: 612  DTASKPSDEVEP---KESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSE 668
             +   P+    P   +ES     +  G     V         R ++   + +        
Sbjct: 3923 HSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRP------ 3976

Query: 669  LQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEE-- 726
                    A THT+   E S        +   +        T L        LG+E    
Sbjct: 3977 --------ASTHTTLFTEDSTTSGLT-EESTAFPGSPASTQTGLPATLTTADLGEESTTF 4027

Query: 727  PPAFESTKSQF--------GSPGPSDAARNLPLESTKSPAEPSKSVPSL-EGPTGF--QP 775
            P +  ST ++         G  G S  +R  P  +  +    S + PSL E  T F   P
Sbjct: 4028 PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 4087

Query: 776  RTP----KPGSGSESG-KERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPS 830
            R+P     P + + SG  E  +TS       HT++F  S +    SGL  E       P+
Sbjct: 4088 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTT---SGLSQE-------PT 4137

Query: 831  PPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRS 890
               +  G +  +L P      ++          P   +T   P         E   P  S
Sbjct: 4138 TSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHS 4197

Query: 891  QTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQES----NVSLSGSSRS 946
             T   L     P       L E  +S+   S+ SS   + SP   +     VS +  SR 
Sbjct: 4198 ST-GSLHTTLTPASSTSTGLQE--ESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRP 4254

Query: 947  ASFERDDHGKAEAP----SPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHS 1002
            +S        +         S+ +   P  T     P+    A  +       SP  S S
Sbjct: 4255 SSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRS--ATSVLVGEPTTSPISSGS 4312

Query: 1003 AHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQA--SLSRPPESELE 1060
               T     +   G    +     +P +P   ++P       +  ++  S SRP      
Sbjct: 4313 TETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTT 4372

Query: 1061 VAPKGRQE---SEEPQPSSSKPSAKSSLSQISSAATSHGGPPGG---KGPGQDRPPLGPT 1114
              P        S+E   S S P +  +     S   S  GP        PG     L P 
Sbjct: 4373 AFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPD 4432

Query: 1115 VPYTEALQVFHHPVAQTPLHEKPYLPPPVSLF------SFQHLVQHEPGQSPEFFSTQAM 1168
                  L     PV  +       L P  S        +FQ     +        +T A 
Sbjct: 4433 NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAF 4492

Query: 1169 SSLLSSPYSMPPLPPSL-FQAPPLPL----QPTVLHPGQLHLPQLMPHPANIPFRQPPSF 1223
              L ++ +  P   P+  F A    L    + T +H   +      P PA    R   S 
Sbjct: 4493 VELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPV-ATATTPSPA----RSTTSG 4547

Query: 1224 L---PMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTE 1280
            L      Y +S   +     P  +  + +      SH     T  +  +T SA +   T 
Sbjct: 4548 LVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTS 4607

Query: 1281 YSSDIRLPPVA--PPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTL 1338
            Y S          P +S+++  S    A  +  D   ++V+P R  T++    S    T 
Sbjct: 4608 YHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES----TT 4663

Query: 1339 SQILVTQSQGSSATVALPKFEEPPS---KGTTVCGADVH------EVGPGPSGLSEEQSR 1389
            S I    S GS  T ALP     P    K TT   +                G SEE + 
Sbjct: 4664 SPI----SSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTT 4719

Query: 1390 AFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKR 1449
               +P        P R  TS   E   +     S+ G ++ +  P  S           R
Sbjct: 4720 VHSSPVATATTPSPARSTTSGLVEESTAYH---SSPGSTQTMHFPESSTA-------SGR 4769

Query: 1450 VKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKS-------HLGNQGQGRRELEMLSSL 1502
             +E   S +     +  P S      E+      S       H           E  ++ 
Sbjct: 4770 SEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTAS 4829

Query: 1503 SSDPSDTKEIPPLPHPALSHGTAPG--SEALKEYPQP-------SGKPHRRGLTPLSVKK 1553
             S P DT  I PLP    +H T  G  +E+   Y  P       +      GL+  S   
Sbjct: 4830 HSSP-DTNGITPLP----AHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTIL 4884

Query: 1554 EDSKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVS 1605
              S   PD      P+S+  S  S  P       +S     FP+  TT+ +S
Sbjct: 4885 YSSSRSPD--QTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLS 4934



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 272/1401 (19%), Positives = 444/1401 (31%), Gaps = 225/1401 (16%)

Query: 269  PGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSS---GLYSSGS----HSSSH 321
            PG          +T S    ++T  H +  SPR      SS   GL    +    H +S 
Sbjct: 2642 PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPAST 2701

Query: 322  ERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFL 381
                   S+    +E+   +       P +H P  + T         SE+  +       
Sbjct: 2702 HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGH------SEKSTIFHSSPDA 2755

Query: 382  SPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLL 441
            S  +  S  S    R ES   ++SP +T   +    + G     G   A  T  S+ P  
Sbjct: 2756 SGTTPSSAHSTTSGRGESTTSRISPGSTEITT----LPGSTTTPGLSEASTTFYSS-PRS 2810

Query: 442  PLSTEDKPSLVPLSV-------------------PRTQVIEHITKLITINEAVVDTSEID 482
            P +T    S+  L V                   P +     +++  T   +    S   
Sbjct: 2811 PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTET 2870

Query: 483  SVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHS 542
            +V PR ++ S R   E P ++ +  P S+H+     + +   L    +  P  P      
Sbjct: 2871 TVFPRSTTTSVRG--EEP-TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG 2927

Query: 543  MPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYS 602
            +P+   T               +  T   + S S+    S  R      +    L GE +
Sbjct: 2928 LPATLTTA-----------DLGEESTTFPSSSGSTGTTLSPAR------STTSGLVGEST 2970

Query: 603  SEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHK 662
                 PSS +T + P     P  SE +       ++           +     ++  +H 
Sbjct: 2971 PSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSH- 3029

Query: 663  KYYCSELQIAKPISAGTHTSPEA-EKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSL 721
                     ++P S  T   P++   S +  EP +   H   G+T E T         SL
Sbjct: 3030 ---------SQPGSTHTTAFPDSTTTSGLSQEPTAS--HSSQGST-EATLSPGSTTASSL 3077

Query: 722  GDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPG 781
            G  ++   F S+        P D    L  + T +      S P+    TG    T  P 
Sbjct: 3078 G--QQSTTFHSS--------PGDTETTLLPDDTITSGLVEASTPT-HSSTGSLHTTLTPA 3126

Query: 782  SGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLA----QFPSPPPAPHG 837
            S + +G +  +T+ +       S    SD+   P G       ++      PS  P  H 
Sbjct: 3127 SSTSAGLQEESTTFQ-------SWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHF 3179

Query: 838  RSAHSLQPKLVRQPNI-QVPEILVTE-EPDRPDT-----EPEPPPKEPEKTEEFQWPQRS 890
             ++ +   +      +   P    T   P R  T     EP   P     TE    P  S
Sbjct: 3180 SASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALP-GS 3238

Query: 891  QTLAQLPAEKL----PPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRS 946
             T A L  +       P+     L+  + +S   S ES+   SR P      +  GS+  
Sbjct: 3239 TTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSR-PGSTHTTAFPGSTTM 3297

Query: 947  ASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMT 1006
                ++      +P  S+D    P  T   T  S  P +     +     P  + +  + 
Sbjct: 3298 PGVSQESTASHSSPG-STDTTLSPGST---TASSLGPES-----TTFHSGPGSTETTLLP 3348

Query: 1007 ETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPES-ELEVAPKG 1065
            +  + S   G L  + P   +  +P   ++P            S +R  ES   +  P  
Sbjct: 3349 DNTTAS---GLLEASTPVHSSTGSPHTTLSP----------AGSTTRQGESTTFQSWPNS 3395

Query: 1066 RQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFH 1125
            +  +  P      P+  S+  ++S+  TSHG P              PT  ++ +     
Sbjct: 3396 KDTTPAP------PTTTSAFVELST--TSHGSPSS-----------TPTTHFSASSTTLG 3436

Query: 1126 HPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLP-PS 1184
                 T +H  P                  P +S      +  ++  SSP S   +  P 
Sbjct: 3437 RSEESTTVHSSPVATATTP----------SPARSTTSGLVEESTTYHSSPGSTQTMHFPE 3486

Query: 1185 LFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQS 1244
                     + T  H    H     P   +    +P S+   P  T++        P  S
Sbjct: 3487 SDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATT-----HFPDSS 3541

Query: 1245 QFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPP 1304
              + +      SH  Q        ATG+  L   +  S  +     +P +S S  T+A P
Sbjct: 3542 TTSGRSEESTASHSSQD-------ATGTIVLPARSTTSVLLGESTTSPISSGSMETTALP 3594

Query: 1305 --LALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQ--GSSATVALPKFEE 1360
                 P   +   +     R      S  S   + +S+   T     GS+ T A P    
Sbjct: 3595 GSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTT 3654

Query: 1361 PPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEG 1420
             P                   GLS   + +  +P       LP    TS SS+   +   
Sbjct: 3655 TP-------------------GLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTT--- 3692

Query: 1421 SSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKR 1480
            S S++G +   LSP  +  L+   +         ++      +      +V  ST     
Sbjct: 3693 SHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAST----- 3747

Query: 1481 PEKSHLGNQGQGRRELEMLSSLS-----------SDPSDTKEIPPLPHPALSHGTAPGSE 1529
              + H  + G  R  L   SS S           + P+ T   P  P    S  TAP  E
Sbjct: 3748 --RVH-SSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPP----STATAPVEE 3800

Query: 1530 ALKEYPQPSGKP--HRRGLTPLSVKKEDS---KEQPDLPSLAPPSSLPLSETSSRPAKSQ 1584
            +   +  P   P  H    +  S   E S      PD     P S+   +        S+
Sbjct: 3801 STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR 3860

Query: 1585 EGTDSKKVLQFPSLHTTTNVS 1605
                S ++   P   TT  +S
Sbjct: 3861 ISPGSTEITTLPGSTTTPGLS 3881



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 352/1805 (19%), Positives = 566/1805 (31%), Gaps = 255/1805 (14%)

Query: 6    SVKGTKKAEGSPRKRLTKGEAIQTSVS-SSVPYPGSGTAATQESPAQELLAPQPFPGPSS 64
            S  G+ +    P    T G   +++ S SS  +  S   +T  +  +E  +    PG ++
Sbjct: 3474 SSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTA 3533

Query: 65   VLR-EGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVD 123
                  S   +G+ ++       + +     LP    T   +       +  GS      
Sbjct: 3534 TTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTAL 3593

Query: 124  PMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKE 183
            P      GS   PGL  +S     H+S       P  P   +   S  S   +EE+    
Sbjct: 3594 P------GSTTTPGLSEKSTTF--HSS-------PRSPATTLSPASTTSSGVSEESTTSH 3638

Query: 184  RKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHA 243
                +PG             P + +    SH+            S  T  +  +   SH+
Sbjct: 3639 ---SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHS 3695

Query: 244  HRIKAGLASGMGG----EMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELS 299
                   A   G                 PG          +T S    ++T  H +  S
Sbjct: 3696 SSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS 3755

Query: 300  PRPKQPLLSS---GLYSSGS----HSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSH 352
            PR      SS   GL    +    H +S        S+    +E+   +       P +H
Sbjct: 3756 PRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTH 3815

Query: 353  KPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAK 412
             P  + T         SE+  +       S  +  S  S    R ES   ++SP +T   
Sbjct: 3816 FPASSTTSGH------SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT 3869

Query: 413  SYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITIN 472
            +      G     G   A  T  S+ P  P +T    S+  L V      E  T      
Sbjct: 3870 TLP----GSTTTPGLSEASTTFYSS-PRSPTTTLSPASMTSLGVGE----ESTTSRSQPG 3920

Query: 473  EAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTA 532
                  S   +  P  S  S      SP S+       S +   + E+       P ST 
Sbjct: 3921 STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTH 3980

Query: 533  PPVPLLRSHSMPSAACTIST--PHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRML--K 588
                L    S  S     ST  P  P          +T ++ L   S  F S       K
Sbjct: 3981 --TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTAD-LGEESTTFPSSSGSTGTK 4037

Query: 589  RQPAIELPLG--GEYSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECN 646
              PA     G  GE +     PSS +T + P     P  SE +       ++        
Sbjct: 4038 LSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 4097

Query: 647  ICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEK-SQIEHEPWSQMMHYKLGT 705
               +     ++  +H          ++P S  T   P++   S +  EP +   H   G+
Sbjct: 4098 TTTSSGVSEESSTSH----------SQPGSTHTTAFPDSTTTSGLSQEPTTS--HSSQGS 4145

Query: 706  TLELTPLRKRRKEKSLGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVP 765
            T E T         SLG  ++   F S+        P D    L  + T +      S P
Sbjct: 4146 T-EATLSPGSTTASSLG--QQSTTFHSS--------PGDTETTLLPDDTITSGLVEASTP 4194

Query: 766  SLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGE-DKP 824
            +    TG    T  P S + +G +  +T+ +       SS + + S    + +  E    
Sbjct: 4195 T-HSSTGSLHTTLTPASSTSTGLQEESTTFQ----SWPSSSDTTPSPPSTTAVPVEVSTT 4249

Query: 825  LAQFPSPPPAPHGRSAHSLQPKLVRQPNIQV-PEILVTEE-PDRPDT-----EPEPPPKE 877
                PS  P  H  ++ +   +      +   P    T   P R  T     EP   P  
Sbjct: 4250 YHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPIS 4309

Query: 878  PEKTEEFQWPQRSQTLAQLPAEKLP----PKKKRLRLAEMAQSSGESSFESSVPLSRSPS 933
               TE    P  S T A L  +       P+     L+  + +S   S ES+   SR  S
Sbjct: 4310 SGSTETTALPG-STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGS 4368

Query: 934  QE-----SNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREM 988
                   S+ ++ G S+ ++      G  +            LG    T  S        
Sbjct: 4369 MHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS-------- 4420

Query: 989  RRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQ 1048
                   SP  + +  + +  + S   G L  + P   +  +P   ++P           
Sbjct: 4421 -------SPGSTETTLLPDNTTAS---GLLEASTPVHSSTGSPHTTLSPA---------- 4460

Query: 1049 ASLSRPPESE-LEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQD 1107
             S +R  ES   +  P  +  +  P      P+  S+  ++S+  TSHG P         
Sbjct: 4461 GSTTRQGESTTFQSWPNSKDTTPAP------PTTTSAFVELST--TSHGSPSST------ 4506

Query: 1108 RPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQA 1167
                 PT  ++ +          T +H  P                  P +S      + 
Sbjct: 4507 -----PTTHFSASSTTLGRSEESTTVHSSPVATATTP----------SPARSTTSGLVEE 4551

Query: 1168 MSSLLSSPYSMPPLP-PSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPM 1226
             ++  SSP S   +  P          + T  H    H     P   +    +P S+   
Sbjct: 4552 STTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSS 4611

Query: 1227 P-------YPTSSALSSG----------------FFLPLQSQFALQLPGDVESHLPQ--I 1261
            P       +P SS  S                    LP +S  ++ L     S +    +
Sbjct: 4612 PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM 4671

Query: 1262 KTSLAPLATGSAGLSP--STEYSSDIRLPPVAPPASSSA-PTSAPPLALPACPDTMVSLV 1318
            +T+  P +T + GLS   +T +SS    P     ASS+    S     + + P    +  
Sbjct: 4672 ETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTP 4731

Query: 1319 VPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGT---TVCGADVHE 1375
             P R  T+     S  Y +        S GS+ T+  P+      +     T   +  H 
Sbjct: 4732 SPARSTTSGLVEESTAYHS--------SPGSTQTMHFPESSTASGRSEESRTSHSSTTHT 4783

Query: 1376 VGPGPS---GLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAG------ 1426
            +   PS    L EE +    +P        PE   TS  SE   +   S  T G      
Sbjct: 4784 ISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPA 4843

Query: 1427 ---GSKRV-------LSPAGSLELTMET-------QQQKRVKEEEASKADEKLELVKPCS 1469
                S R+       +SP GS+E T+ +         +  +    +   D+ L    P S
Sbjct: 4844 HFTTSGRIAESTTFYISP-GSMETTLASTATTPGLSAKSTILYSSSRSPDQTLS---PAS 4899

Query: 1470 VVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALSHGT-APGS 1528
            +  +S       E + L +Q +        +S ++     +       P  +  T +PGS
Sbjct: 4900 MTSSSISG----EPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGS 4955

Query: 1529 EALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPP--SSLPLSETSSRPAKSQEG 1586
                 + Q    PH +  + LS     S   P L   +    SS   +ET++    +   
Sbjct: 4956 ITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMS 5015

Query: 1587 TDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHAD--RRSSVYAGWCISLYNPNLPGVST 1644
              S++   FP     T+        + P  +   D  + S+ +     +     LP  ST
Sbjct: 5016 IHSQQSTPFPDSPGFTHT-------VLPATLTTTDIGQESTAFHSSSDATGTTPLPARST 5068

Query: 1645 KAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLAR 1704
             + L           E  T   +P P    L P+SS    +TE       SP     +  
Sbjct: 5069 ASDLV---------GEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVS 5119

Query: 1705 VEKEE 1709
             E  E
Sbjct: 5120 TESLE 5124



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 62/273 (22%), Positives = 90/273 (32%), Gaps = 45/273 (16%)

Query: 1868 EESQDELSRPSSE----APPPGPPHALRADSSPILGPQPPDA-----PASGTEATRGSSV 1918
            EES    S+P S     +P       L  +S+ +    P        P + T + RG   
Sbjct: 2353 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEP 2412

Query: 1919 SE-------------AERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSP 1965
            +               E  T S  +  S + PG P        S +    + L+   +  
Sbjct: 2413 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSP-------ASTQTGLPATLTTADLGE 2465

Query: 1966 RRPWSPSKEAGSRPPLARKHSLTKN---DSSPQRCSPAREPQASAP-SPPGLHVDPGRGM 2021
                 PS    +   L+   S T     +S+P R SP+     + P SP    +      
Sbjct: 2466 ESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTT 2525

Query: 2022 GALPCGSPRLQLSPLTLCPLG--------RELAPRAHVLSKLEGTTDPGLPRYSPTRRWS 2073
                  SP   LSP T    G               H  +  + TT PGL R+S T   S
Sbjct: 2526 FYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSS 2585

Query: 2074 PGQAESPPRSAPPGKWALAGPGSPSAGEH-GPG 2105
            PG  ++   +  P     +GP   S   H  PG
Sbjct: 2586 PGSTDT---TLLPASTTTSGPSQESTTSHSSPG 2615



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 130/539 (24%), Positives = 176/539 (32%), Gaps = 85/539 (15%)

Query: 1869 ESQDELSRPSSEAPPPGPPHALRA--DSSPILGPQPPDAPASGTEATRGSSVSEAERLTA 1926
            ES    S PSS+   P PP    A  + S      P   P +   A+  +     E  T 
Sbjct: 1828 ESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTV 1887

Query: 1927 SSCSMSSQSMPGLPWLGPA---PLGSVEKDTGSALSYKPVSPRRPWSP-SKEAGSRPPLA 1982
             S  +++ + P      PA     G VE+ T  A    P S +    P S  A  R   +
Sbjct: 1888 HSSPVATATTPS-----PARSTTSGLVEEST--AYHSSPGSTQTMHFPESSTASGRSEES 1940

Query: 1983 R-KHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPL 2041
            R  HS T +  S    SP     A    P   H  PG         S      P +    
Sbjct: 1941 RTSHSSTTHTIS----SPPSTTSALVEEPTSYHSSPG---------STATTHFPDSSTTS 1987

Query: 2042 GR-ELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAG 2100
            GR E +  +H      GT    LP  S T         SP  S      AL  PGS +  
Sbjct: 1988 GRSEESTASHSSQDATGTIV--LPARSTTSVLLGESTTSPISSGSMETTAL--PGSTTT- 2042

Query: 2101 EHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSAL 2160
               PGL  +    F  +P       RSP T  SP    S   S     +H   SRP S  
Sbjct: 2043 ---PGLS-EKSTTFHSSP-------RSPATTLSPASTTSSGVSEESTTSH---SRPGST- 2087

Query: 2161 HDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAW 2220
                 H  A  +      L  HS     +P       G       P +  T   GP+   
Sbjct: 2088 -----HTTAFPDSTTTPGLSRHSTTSHSSP-------GSTDTTLLPAS--TTTSGPSQES 2133

Query: 2221 VSGFSGGGSDLT----GAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKE 2276
             +  S  GS  T    G+  A   G+ S T  SS   +        T SS +      + 
Sbjct: 2134 TTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAS-TRV 2192

Query: 2277 RERTGG-------GPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSP 2329
               TG             P      T     P  TH+  +PP T   P +     +S + 
Sbjct: 2193 HSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVE-----ESTTY 2247

Query: 2330 RLESPRAPTNPEPSATPP---LDRSSSVGCLAEASARFPARTRNLS---GEPRTRQDSP 2382
                   PT   P+++      ++S+      +AS   P+   + +   GE  T + SP
Sbjct: 2248 HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISP 2306


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 135/596 (22%), Positives = 190/596 (31%), Gaps = 100/596 (16%)

Query: 755  KSPAEPS-KSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSF------- 806
            K PA P  ++ P  E        +P   S S +  +  T  K    ++  +S        
Sbjct: 36   KQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKR 95

Query: 807  --EKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEP 864
              EK  S  + +      K   Q  S P +P      S   + V       P+ +   + 
Sbjct: 96   QREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDI---DQ 152

Query: 865  DRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFES 924
            D   T P  P  +  +++     Q+    AQ PA + P             +   SS   
Sbjct: 153  DNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT----------GVTPAPSSAPP 202

Query: 925  SVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPS-PSSDMRPKPLGTHMLTVPSHHP 983
              P   +P    + +      S +        ++AP+ P +   P P  TH+   P+ HP
Sbjct: 203  GTPQLPTPGPTPSATAVPPQGSPT-------ASQAPNQPQAPTAPVP-HTHIQQAPALHP 254

Query: 984  HAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKC 1043
                        SP   H      T S            PSAP+   PP     P     
Sbjct: 255  QRPPSPHPPPHPSP---HPPLQPLTGSAG---------QPSAPSHAQPPLHGQGPPGPHS 302

Query: 1044 F----LVRQAS----LSRPPESELEVAPKGRQESEE-PQPSSSKPSAKSSLSQISSAATS 1094
                 L++          PP++    AP G   +   P  S   P+++S+L Q       
Sbjct: 303  LQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL-QSQQPPRE 361

Query: 1095 HGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHP---VAQTPLHEKPYLPPPVSLFSFQHL 1151
               PP        +PP    +P   A Q   HP      +P      LPPP +L     L
Sbjct: 362  QPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 421

Query: 1152 -VQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMP 1210
               H P   P        S  L    S P  PP L Q+  LP  P    P  LH  Q+ P
Sbjct: 422  STHHPPSAHPPPLQLMPQSQPLP---SSPAQPPGLTQSQNLPPPPASHPPTGLH--QVAP 476

Query: 1211 HPANIPFRQ-------PPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKT 1263
             P   PF Q       PP   P   P++S   +G             PG          T
Sbjct: 477  QP---PFAQHPFVPGGPPPITPPTCPSTSTPPAG-------------PG----------T 510

Query: 1264 SLAPLATGSAGLSPSTEYSSDIRLPPVAPPA----SSSAPTSAPPLALPACPDTMV 1315
            S  P  +G+A    S    S   LP V         +  P S PP      P+  V
Sbjct: 511  SAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTV 566



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 133/588 (22%), Positives = 193/588 (32%), Gaps = 129/588 (21%)

Query: 1792 KTKGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLE 1851
            K+   + +   S   S K Q   V  + E  + TS      S+  +  E    +  S+ E
Sbjct: 77   KSAKKVKEEASSPLKSNKRQREKVASDTEEADRTS------SKKTKTQEISRPNSPSEGE 130

Query: 1852 DSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSS---PILGPQPP--DAP 1906
               SDS    DE   + +  D+ +R +S + P    +   +DSS    +L  QPP   AP
Sbjct: 131  GESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAP 190

Query: 1907 ASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPR 1966
               T A                 S +    P LP  GP P  +     GS  + +  +P 
Sbjct: 191  TGVTPAP----------------SSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ--APN 232

Query: 1967 RPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQ-ASAPSPPGLHVDPGRGMGALP 2025
            +P +P+       P+   H          + +PA  PQ   +P PP             P
Sbjct: 233  QPQAPT------APVPHTHI---------QQAPALHPQRPPSPHPP-------------P 264

Query: 2026 CGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPP---R 2082
              SP   L PLT    G+  AP +H    L G   PG           P   ++ P    
Sbjct: 265  HPSPHPPLQPLT-GSAGQPSAP-SHAQPPLHGQGPPG-----------PHSLQAGPLLQH 311

Query: 2083 SAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPL-----PHKLLSRSPETCASPWKA 2137
              PP  + L     P A +    LG  P   +P   L        L S+ P        A
Sbjct: 312  PGPPQPFGL----PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPA 367

Query: 2138 ESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIG 2197
                P   P P  P+   P    H    H+   +  ++ ++LP         P  L P+ 
Sbjct: 368  PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLP--------PPPALKPLS 419

Query: 2198 GIQMVQARPGAHPTLLP-GPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPV 2256
             +      P AHP  L   P +  +         LT ++         P       +  V
Sbjct: 420  SLS-THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP----PPASHPPTGLHQV 474

Query: 2257 AKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPR 2316
            A    F     +               PG PP  TP     P  P+ T +P   P T  +
Sbjct: 475  APQPPFAQHPFV---------------PGGPPPITP-----PTCPS-TSTPPAGPGTSAQ 513

Query: 2317 PPQGRRAAQSWS-----------PRLESPRAPTNPEPSATPPLDRSSS 2353
            PP    AA   S            +++        EP + PP  RS S
Sbjct: 514  PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPS 561



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 98/449 (21%), Positives = 149/449 (33%), Gaps = 92/449 (20%)

Query: 724  EEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQ-PRTPKPGS 782
            + +PPA ++      +P PS A    P   T  P   + +VP    PT  Q P  P+  +
Sbjct: 181  QAQPPALQAPTGV--TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 238

Query: 783  GSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPH------ 836
                           + + HT        ++Q   L  + +P +  P P P+PH      
Sbjct: 239  ---------------APVPHT-------HIQQAPALHPQ-RPPSPHPPPHPSPHPPLQPL 275

Query: 837  -GRSAHSLQPKLVRQP----------NIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQ 885
             G +     P   + P          ++Q   +L    P +P   P    +         
Sbjct: 276  TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP 335

Query: 886  WPQRSQTLAQLPA------EKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESN-V 938
                  T  QLPA       + PP+++ L  A +A    +    + +P   +P    +  
Sbjct: 336  AAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPP 395

Query: 939  SLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPN 998
             LSG S  +         A  P P +      L TH    PS HP   ++   +     +
Sbjct: 396  HLSGPSPFSM-------NANLPPPPALKPLSSLSTH--HPPSAHPPPLQLMPQSQPLPSS 446

Query: 999  VSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESE 1058
             +    +T+         S +L  P A  P     +VAP               +PP ++
Sbjct: 447  PAQPPGLTQ---------SQNLPPPPASHPPTGLHQVAP---------------QPPFAQ 482

Query: 1059 LEVAPKGRQESEEPQ-PSSSKPSA---KSSLSQISSAATSHGGPPGGKGPGQDRPPLGPT 1114
                P G      P  PS+S P A    S+    S AA S G   GG        PL   
Sbjct: 483  HPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTV 537

Query: 1115 VPYTEALQVFHHPVAQTPLHEKPYLPPPV 1143
                EAL     P +  P    P   P V
Sbjct: 538  QIKEEALDDAEEPESPPPPPRSPSPEPTV 566



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 42/150 (28%), Positives = 53/150 (35%), Gaps = 25/150 (16%)

Query: 30  SVSSSVPYPGSGTAATQESPAQELLAPQP--FPGPSSVLREGSQEKTGQQQKPPKRP--- 84
           S S S+P P    + +  S  Q++L  QP     P+ V    S    G  Q P   P   
Sbjct: 156 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS 215

Query: 85  ----PIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHP 140
               P + S   SQ P  P  P   +P    H+ +      + P RP        P  HP
Sbjct: 216 ATAVPPQGSPTASQAPNQPQAPT--APVPHTHIQQAPA---LHPQRPPSPHPPPHPSPHP 270

Query: 141 QSQLL---------PSHASIIPPEDLPGVP 161
             Q L         PSHA   PP    G P
Sbjct: 271 PLQPLTGSAGQPSAPSHAQ--PPLHGQGPP 298



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 43/144 (29%), Positives = 50/144 (34%), Gaps = 32/144 (22%)

Query: 29  TSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEA 88
           T  +++VP  GS TA+   +  Q   AP P               T  QQ P   P    
Sbjct: 213 TPSATAVPPQGSPTASQAPNQPQAPTAPVP--------------HTHIQQAPALHP---- 254

Query: 89  SVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSH 148
                Q P  P  P   SP  P   L GS  Q   P  P    S   P LH Q    P  
Sbjct: 255 -----QRPPSPHPPPHPSPHPPLQPLTGSAGQ---PSAP----SHAQPPLHGQGPPGPHS 302

Query: 149 ASIIPPEDLPGVPKVF--VPRPSQ 170
               P    PG P+ F   P+ SQ
Sbjct: 303 LQAGPLLQHPGPPQPFGLPPQASQ 326



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 50/213 (23%), Positives = 74/213 (34%), Gaps = 21/213 (9%)

Query: 2200 QMVQARPGA--HPT-LLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPV 2256
            QM+QA+P A   PT + P P++A       G   L             P  S +AS +P 
Sbjct: 178  QMLQAQPPALQAPTGVTPAPSSA-----PPGTPQLPTPGPTPSATAVPPQGSPTASQAPN 232

Query: 2257 AKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHG-----TGAPAEPT-PTHSPCTP 2310
               +             P    +    P  PP  +PH      TG+  +P+ P+H+    
Sbjct: 233  QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQ--- 289

Query: 2311 PDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRN 2370
            P    + P G  + Q+  P L+ P  P   +P   PP             +A +P  +  
Sbjct: 290  PPLHGQGPPGPHSLQA-GPLLQHPGPP---QPFGLPPQASQGQAPLGTSPAAAYPHTSLQ 345

Query: 2371 LSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPP 2403
            L       Q    P     P A    P  + PP
Sbjct: 346  LPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 378


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 135/596 (22%), Positives = 190/596 (31%), Gaps = 100/596 (16%)

Query: 755  KSPAEPS-KSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSF------- 806
            K PA P  ++ P  E        +P   S S +  +  T  K    ++  +S        
Sbjct: 590  KQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKR 649

Query: 807  --EKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEP 864
              EK  S  + +      K   Q  S P +P      S   + V       P+ +   + 
Sbjct: 650  QREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDI---DQ 706

Query: 865  DRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFES 924
            D   T P  P  +  +++     Q+    AQ PA + P             +   SS   
Sbjct: 707  DNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT----------GVTPAPSSAPP 756

Query: 925  SVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPS-PSSDMRPKPLGTHMLTVPSHHP 983
              P   +P    + +      S +        ++AP+ P +   P P  TH+   P+ HP
Sbjct: 757  GTPQLPTPGPTPSATAVPPQGSPT-------ASQAPNQPQAPTAPVP-HTHIQQAPALHP 808

Query: 984  HAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKC 1043
                        SP   H      T S            PSAP+   PP     P     
Sbjct: 809  QRPPSPHPPPHPSP---HPPLQPLTGSAG---------QPSAPSHAQPPLHGQGPPGPHS 856

Query: 1044 F----LVRQAS----LSRPPESELEVAPKGRQESEE-PQPSSSKPSAKSSLSQISSAATS 1094
                 L++          PP++    AP G   +   P  S   P+++S+L Q       
Sbjct: 857  LQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL-QSQQPPRE 915

Query: 1095 HGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHP---VAQTPLHEKPYLPPPVSLFSFQHL 1151
               PP        +PP    +P   A Q   HP      +P      LPPP +L     L
Sbjct: 916  QPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 975

Query: 1152 -VQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMP 1210
               H P   P        S  L    S P  PP L Q+  LP  P    P  LH  Q+ P
Sbjct: 976  STHHPPSAHPPPLQLMPQSQPLP---SSPAQPPGLTQSQNLPPPPASHPPTGLH--QVAP 1030

Query: 1211 HPANIPFRQ-------PPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKT 1263
             P   PF Q       PP   P   P++S   +G             PG          T
Sbjct: 1031 QP---PFAQHPFVPGGPPPITPPTCPSTSTPPAG-------------PG----------T 1064

Query: 1264 SLAPLATGSAGLSPSTEYSSDIRLPPVAPPA----SSSAPTSAPPLALPACPDTMV 1315
            S  P  +G+A    S    S   LP V         +  P S PP      P+  V
Sbjct: 1065 SAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTV 1120



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 133/588 (22%), Positives = 193/588 (32%), Gaps = 129/588 (21%)

Query: 1792 KTKGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLE 1851
            K+   + +   S   S K Q   V  + E  + TS      S+  +  E    +  S+ E
Sbjct: 631  KSAKKVKEEASSPLKSNKRQREKVASDTEEADRTS------SKKTKTQEISRPNSPSEGE 684

Query: 1852 DSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSS---PILGPQPP--DAP 1906
               SDS    DE   + +  D+ +R +S + P    +   +DSS    +L  QPP   AP
Sbjct: 685  GESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAP 744

Query: 1907 ASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPR 1966
               T A                 S +    P LP  GP P  +     GS  + +  +P 
Sbjct: 745  TGVTPAP----------------SSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ--APN 786

Query: 1967 RPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQ-ASAPSPPGLHVDPGRGMGALP 2025
            +P +P+       P+   H          + +PA  PQ   +P PP             P
Sbjct: 787  QPQAPT------APVPHTHI---------QQAPALHPQRPPSPHPP-------------P 818

Query: 2026 CGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPP---R 2082
              SP   L PLT    G+  AP +H    L G   PG           P   ++ P    
Sbjct: 819  HPSPHPPLQPLT-GSAGQPSAP-SHAQPPLHGQGPPG-----------PHSLQAGPLLQH 865

Query: 2083 SAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPL-----PHKLLSRSPETCASPWKA 2137
              PP  + L     P A +    LG  P   +P   L        L S+ P        A
Sbjct: 866  PGPPQPFGL----PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPA 921

Query: 2138 ESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIG 2197
                P   P P  P+   P    H    H+   +  ++ ++LP         P  L P+ 
Sbjct: 922  PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLP--------PPPALKPLS 973

Query: 2198 GIQMVQARPGAHPTLLP-GPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPV 2256
             +      P AHP  L   P +  +         LT ++         P       +  V
Sbjct: 974  SLS-THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP----PPASHPPTGLHQV 1028

Query: 2257 AKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPR 2316
            A    F     +               PG PP  TP     P  P+ T +P   P T  +
Sbjct: 1029 APQPPFAQHPFV---------------PGGPPPITP-----PTCPS-TSTPPAGPGTSAQ 1067

Query: 2317 PPQGRRAAQSWS-----------PRLESPRAPTNPEPSATPPLDRSSS 2353
            PP    AA   S            +++        EP + PP  RS S
Sbjct: 1068 PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPS 1115



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 98/449 (21%), Positives = 149/449 (33%), Gaps = 92/449 (20%)

Query: 724  EEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQ-PRTPKPGS 782
            + +PPA ++      +P PS A    P   T  P   + +VP    PT  Q P  P+  +
Sbjct: 735  QAQPPALQAPTGV--TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 792

Query: 783  GSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPH------ 836
                           + + HT        ++Q   L  + +P +  P P P+PH      
Sbjct: 793  ---------------APVPHT-------HIQQAPALHPQ-RPPSPHPPPHPSPHPPLQPL 829

Query: 837  -GRSAHSLQPKLVRQP----------NIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQ 885
             G +     P   + P          ++Q   +L    P +P   P    +         
Sbjct: 830  TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP 889

Query: 886  WPQRSQTLAQLPA------EKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESN-V 938
                  T  QLPA       + PP+++ L  A +A    +    + +P   +P    +  
Sbjct: 890  AAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPP 949

Query: 939  SLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPN 998
             LSG S  +         A  P P +      L TH    PS HP   ++   +     +
Sbjct: 950  HLSGPSPFSM-------NANLPPPPALKPLSSLSTH--HPPSAHPPPLQLMPQSQPLPSS 1000

Query: 999  VSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESE 1058
             +    +T+         S +L  P A  P     +VAP               +PP ++
Sbjct: 1001 PAQPPGLTQ---------SQNLPPPPASHPPTGLHQVAP---------------QPPFAQ 1036

Query: 1059 LEVAPKGRQESEEPQ-PSSSKPSA---KSSLSQISSAATSHGGPPGGKGPGQDRPPLGPT 1114
                P G      P  PS+S P A    S+    S AA S G   GG        PL   
Sbjct: 1037 HPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTV 1091

Query: 1115 VPYTEALQVFHHPVAQTPLHEKPYLPPPV 1143
                EAL     P +  P    P   P V
Sbjct: 1092 QIKEEALDDAEEPESPPPPPRSPSPEPTV 1120



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 42/150 (28%), Positives = 53/150 (35%), Gaps = 25/150 (16%)

Query: 30  SVSSSVPYPGSGTAATQESPAQELLAPQP--FPGPSSVLREGSQEKTGQQQKPPKRP--- 84
           S S S+P P    + +  S  Q++L  QP     P+ V    S    G  Q P   P   
Sbjct: 710 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS 769

Query: 85  ----PIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHP 140
               P + S   SQ P  P  P   +P    H+ +      + P RP        P  HP
Sbjct: 770 ATAVPPQGSPTASQAPNQPQAPT--APVPHTHIQQAPA---LHPQRPPSPHPPPHPSPHP 824

Query: 141 QSQLL---------PSHASIIPPEDLPGVP 161
             Q L         PSHA   PP    G P
Sbjct: 825 PLQPLTGSAGQPSAPSHAQ--PPLHGQGPP 852



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 43/144 (29%), Positives = 50/144 (34%), Gaps = 32/144 (22%)

Query: 29  TSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEA 88
           T  +++VP  GS TA+   +  Q   AP P               T  QQ P   P    
Sbjct: 767 TPSATAVPPQGSPTASQAPNQPQAPTAPVP--------------HTHIQQAPALHP---- 808

Query: 89  SVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSH 148
                Q P  P  P   SP  P   L GS  Q   P  P    S   P LH Q    P  
Sbjct: 809 -----QRPPSPHPPPHPSPHPPLQPLTGSAGQ---PSAP----SHAQPPLHGQGPPGPHS 856

Query: 149 ASIIPPEDLPGVPKVF--VPRPSQ 170
               P    PG P+ F   P+ SQ
Sbjct: 857 LQAGPLLQHPGPPQPFGLPPQASQ 880



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 50/213 (23%), Positives = 74/213 (34%), Gaps = 21/213 (9%)

Query: 2200 QMVQARPGA--HPT-LLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPV 2256
            QM+QA+P A   PT + P P++A       G   L             P  S +AS +P 
Sbjct: 732  QMLQAQPPALQAPTGVTPAPSSA-----PPGTPQLPTPGPTPSATAVPPQGSPTASQAPN 786

Query: 2257 AKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHG-----TGAPAEPT-PTHSPCTP 2310
               +             P    +    P  PP  +PH      TG+  +P+ P+H+    
Sbjct: 787  QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQ--- 843

Query: 2311 PDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRN 2370
            P    + P G  + Q+  P L+ P  P   +P   PP             +A +P  +  
Sbjct: 844  PPLHGQGPPGPHSLQA-GPLLQHPGPP---QPFGLPPQASQGQAPLGTSPAAAYPHTSLQ 899

Query: 2371 LSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPP 2403
            L       Q    P     P A    P  + PP
Sbjct: 900  LPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 932


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 135/596 (22%), Positives = 190/596 (31%), Gaps = 100/596 (16%)

Query: 755  KSPAEPS-KSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSF------- 806
            K PA P  ++ P  E        +P   S S +  +  T  K    ++  +S        
Sbjct: 590  KQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKR 649

Query: 807  --EKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEP 864
              EK  S  + +      K   Q  S P +P      S   + V       P+ +   + 
Sbjct: 650  QREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDI---DQ 706

Query: 865  DRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFES 924
            D   T P  P  +  +++     Q+    AQ PA + P             +   SS   
Sbjct: 707  DNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT----------GVTPAPSSAPP 756

Query: 925  SVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPS-PSSDMRPKPLGTHMLTVPSHHP 983
              P   +P    + +      S +        ++AP+ P +   P P  TH+   P+ HP
Sbjct: 757  GTPQLPTPGPTPSATAVPPQGSPT-------ASQAPNQPQAPTAPVP-HTHIQQAPALHP 808

Query: 984  HAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKC 1043
                        SP   H      T S            PSAP+   PP     P     
Sbjct: 809  QRPPSPHPPPHPSP---HPPLQPLTGSAG---------QPSAPSHAQPPLHGQGPPGPHS 856

Query: 1044 F----LVRQAS----LSRPPESELEVAPKGRQESEE-PQPSSSKPSAKSSLSQISSAATS 1094
                 L++          PP++    AP G   +   P  S   P+++S+L Q       
Sbjct: 857  LQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL-QSQQPPRE 915

Query: 1095 HGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHP---VAQTPLHEKPYLPPPVSLFSFQHL 1151
               PP        +PP    +P   A Q   HP      +P      LPPP +L     L
Sbjct: 916  QPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 975

Query: 1152 -VQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMP 1210
               H P   P        S  L    S P  PP L Q+  LP  P    P  LH  Q+ P
Sbjct: 976  STHHPPSAHPPPLQLMPQSQPLP---SSPAQPPGLTQSQNLPPPPASHPPTGLH--QVAP 1030

Query: 1211 HPANIPFRQ-------PPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKT 1263
             P   PF Q       PP   P   P++S   +G             PG          T
Sbjct: 1031 QP---PFAQHPFVPGGPPPITPPTCPSTSTPPAG-------------PG----------T 1064

Query: 1264 SLAPLATGSAGLSPSTEYSSDIRLPPVAPPA----SSSAPTSAPPLALPACPDTMV 1315
            S  P  +G+A    S    S   LP V         +  P S PP      P+  V
Sbjct: 1065 SAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTV 1120



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 133/588 (22%), Positives = 193/588 (32%), Gaps = 129/588 (21%)

Query: 1792 KTKGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLE 1851
            K+   + +   S   S K Q   V  + E  + TS      S+  +  E    +  S+ E
Sbjct: 631  KSAKKVKEEASSPLKSNKRQREKVASDTEEADRTS------SKKTKTQEISRPNSPSEGE 684

Query: 1852 DSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSS---PILGPQPP--DAP 1906
               SDS    DE   + +  D+ +R +S + P    +   +DSS    +L  QPP   AP
Sbjct: 685  GESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAP 744

Query: 1907 ASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPR 1966
               T A                 S +    P LP  GP P  +     GS  + +  +P 
Sbjct: 745  TGVTPAP----------------SSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ--APN 786

Query: 1967 RPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQ-ASAPSPPGLHVDPGRGMGALP 2025
            +P +P+       P+   H          + +PA  PQ   +P PP             P
Sbjct: 787  QPQAPT------APVPHTHI---------QQAPALHPQRPPSPHPP-------------P 818

Query: 2026 CGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPP---R 2082
              SP   L PLT    G+  AP +H    L G   PG           P   ++ P    
Sbjct: 819  HPSPHPPLQPLT-GSAGQPSAP-SHAQPPLHGQGPPG-----------PHSLQAGPLLQH 865

Query: 2083 SAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPL-----PHKLLSRSPETCASPWKA 2137
              PP  + L     P A +    LG  P   +P   L        L S+ P        A
Sbjct: 866  PGPPQPFGL----PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPA 921

Query: 2138 ESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIG 2197
                P   P P  P+   P    H    H+   +  ++ ++LP         P  L P+ 
Sbjct: 922  PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLP--------PPPALKPLS 973

Query: 2198 GIQMVQARPGAHPTLLP-GPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPV 2256
             +      P AHP  L   P +  +         LT ++         P       +  V
Sbjct: 974  SLS-THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP----PPASHPPTGLHQV 1028

Query: 2257 AKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPR 2316
            A    F     +               PG PP  TP     P  P+ T +P   P T  +
Sbjct: 1029 APQPPFAQHPFV---------------PGGPPPITP-----PTCPS-TSTPPAGPGTSAQ 1067

Query: 2317 PPQGRRAAQSWS-----------PRLESPRAPTNPEPSATPPLDRSSS 2353
            PP    AA   S            +++        EP + PP  RS S
Sbjct: 1068 PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPS 1115



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 98/449 (21%), Positives = 149/449 (33%), Gaps = 92/449 (20%)

Query: 724  EEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQ-PRTPKPGS 782
            + +PPA ++      +P PS A    P   T  P   + +VP    PT  Q P  P+  +
Sbjct: 735  QAQPPALQAPTGV--TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 792

Query: 783  GSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPH------ 836
                           + + HT        ++Q   L  + +P +  P P P+PH      
Sbjct: 793  ---------------APVPHT-------HIQQAPALHPQ-RPPSPHPPPHPSPHPPLQPL 829

Query: 837  -GRSAHSLQPKLVRQP----------NIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQ 885
             G +     P   + P          ++Q   +L    P +P   P    +         
Sbjct: 830  TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP 889

Query: 886  WPQRSQTLAQLPA------EKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESN-V 938
                  T  QLPA       + PP+++ L  A +A    +    + +P   +P    +  
Sbjct: 890  AAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPP 949

Query: 939  SLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPN 998
             LSG S  +         A  P P +      L TH    PS HP   ++   +     +
Sbjct: 950  HLSGPSPFSM-------NANLPPPPALKPLSSLSTH--HPPSAHPPPLQLMPQSQPLPSS 1000

Query: 999  VSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESE 1058
             +    +T+         S +L  P A  P     +VAP               +PP ++
Sbjct: 1001 PAQPPGLTQ---------SQNLPPPPASHPPTGLHQVAP---------------QPPFAQ 1036

Query: 1059 LEVAPKGRQESEEPQ-PSSSKPSA---KSSLSQISSAATSHGGPPGGKGPGQDRPPLGPT 1114
                P G      P  PS+S P A    S+    S AA S G   GG        PL   
Sbjct: 1037 HPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTV 1091

Query: 1115 VPYTEALQVFHHPVAQTPLHEKPYLPPPV 1143
                EAL     P +  P    P   P V
Sbjct: 1092 QIKEEALDDAEEPESPPPPPRSPSPEPTV 1120



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 42/150 (28%), Positives = 53/150 (35%), Gaps = 25/150 (16%)

Query: 30  SVSSSVPYPGSGTAATQESPAQELLAPQP--FPGPSSVLREGSQEKTGQQQKPPKRP--- 84
           S S S+P P    + +  S  Q++L  QP     P+ V    S    G  Q P   P   
Sbjct: 710 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS 769

Query: 85  ----PIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHP 140
               P + S   SQ P  P  P   +P    H+ +      + P RP        P  HP
Sbjct: 770 ATAVPPQGSPTASQAPNQPQAPT--APVPHTHIQQAPA---LHPQRPPSPHPPPHPSPHP 824

Query: 141 QSQLL---------PSHASIIPPEDLPGVP 161
             Q L         PSHA   PP    G P
Sbjct: 825 PLQPLTGSAGQPSAPSHAQ--PPLHGQGPP 852



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 43/144 (29%), Positives = 50/144 (34%), Gaps = 32/144 (22%)

Query: 29  TSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEA 88
           T  +++VP  GS TA+   +  Q   AP P               T  QQ P   P    
Sbjct: 767 TPSATAVPPQGSPTASQAPNQPQAPTAPVP--------------HTHIQQAPALHP---- 808

Query: 89  SVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSH 148
                Q P  P  P   SP  P   L GS  Q   P  P    S   P LH Q    P  
Sbjct: 809 -----QRPPSPHPPPHPSPHPPLQPLTGSAGQ---PSAP----SHAQPPLHGQGPPGPHS 856

Query: 149 ASIIPPEDLPGVPKVF--VPRPSQ 170
               P    PG P+ F   P+ SQ
Sbjct: 857 LQAGPLLQHPGPPQPFGLPPQASQ 880



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 50/213 (23%), Positives = 74/213 (34%), Gaps = 21/213 (9%)

Query: 2200 QMVQARPGA--HPT-LLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPV 2256
            QM+QA+P A   PT + P P++A       G   L             P  S +AS +P 
Sbjct: 732  QMLQAQPPALQAPTGVTPAPSSA-----PPGTPQLPTPGPTPSATAVPPQGSPTASQAPN 786

Query: 2257 AKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHG-----TGAPAEPT-PTHSPCTP 2310
               +             P    +    P  PP  +PH      TG+  +P+ P+H+    
Sbjct: 787  QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQ--- 843

Query: 2311 PDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRN 2370
            P    + P G  + Q+  P L+ P  P   +P   PP             +A +P  +  
Sbjct: 844  PPLHGQGPPGPHSLQA-GPLLQHPGPP---QPFGLPPQASQGQAPLGTSPAAAYPHTSLQ 899

Query: 2371 LSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPP 2403
            L       Q    P     P A    P  + PP
Sbjct: 900  LPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 932


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.127    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 126,604,795
Number of Sequences: 37866
Number of extensions: 8256035
Number of successful extensions: 99271
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1316
Number of HSP's successfully gapped in prelim test: 2203
Number of HSP's that attempted gapping in prelim test: 39006
Number of HSP's gapped (non-prelim): 53945
length of query: 2405
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2286
effective length of database: 13,741,464
effective search space: 31412986704
effective search space used: 31412986704
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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