Guide to the Human Genome
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Search of human proteins with 189027121

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189027121 solute carrier family 35, member F1 [Homo sapiens]
         (408 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189027121 solute carrier family 35, member F1 [Homo sapiens]       811   0.0  
gi|31542943 solute carrier family 35, member F2 [Homo sapiens]        414   e-116
gi|27735127 solute carrier family 35, member F3 [Homo sapiens]         48   2e-05
gi|31542711 ANT2-binding protein [Homo sapiens]                        45   9e-05
gi|122937311 solute carrier family 35, member F4 [Homo sapiens]        45   1e-04
gi|27881499 solute carrier family 35, member C2 isoform a [Homo ...    43   4e-04
gi|21314776 solute carrier family 35, member C2 isoform a [Homo ...    43   4e-04
gi|19920317 cytoskeleton-associated protein 4 [Homo sapiens]           37   0.042
gi|87299628 biorientation of chromosomes in cell division 1-like...    36   0.072
gi|134254450 patched isoform S [Homo sapiens]                          33   0.36 
gi|134254435 patched isoform S [Homo sapiens]                          33   0.36 
gi|134254468 patched isoform S [Homo sapiens]                          33   0.36 
gi|134254452 patched isoform S [Homo sapiens]                          33   0.36 
gi|134254432 patched isoform L' [Homo sapiens]                         33   0.36 
gi|134254466 patched isoform M [Homo sapiens]                          33   0.36 
gi|134254446 patched isoform L [Homo sapiens]                          33   0.36 
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    33   0.47 
gi|156564359 hypothetical protein LOC113278 [Homo sapiens]             32   0.79 
gi|189491742 ataxin 7 isoform b [Homo sapiens]                         32   1.0  
gi|4506797 ataxin 7 isoform a [Homo sapiens]                           32   1.0  
gi|239752866 PREDICTED: similar to hCG1997308 [Homo sapiens]           32   1.4  
gi|239747418 PREDICTED: hypothetical protein XP_002346694 [Homo ...    32   1.4  
gi|239741243 PREDICTED: hypothetical protein XP_002342142 [Homo ...    32   1.4  
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    32   1.4  
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    31   2.3  
gi|52145305 patched 2 [Homo sapiens]                                   31   2.3  
gi|89257348 homeo box HB9 [Homo sapiens]                               31   2.3  
gi|13128980 proline rich 14 [Homo sapiens]                             31   2.3  
gi|21687252 zinc finger protein 296 [Homo sapiens]                     30   3.0  
gi|5453666 G protein-coupled receptor 19 [Homo sapiens]                30   3.0  

>gi|189027121 solute carrier family 35, member F1 [Homo sapiens]
          Length = 408

 Score =  811 bits (2095), Expect = 0.0
 Identities = 408/408 (100%), Positives = 408/408 (100%)

Query: 1   MIPPEQPQQQLQPPSPAPPNHVVTTIENLPAEGSGGGGSLSASSRAGVRQRIRKVLNREM 60
           MIPPEQPQQQLQPPSPAPPNHVVTTIENLPAEGSGGGGSLSASSRAGVRQRIRKVLNREM
Sbjct: 1   MIPPEQPQQQLQPPSPAPPNHVVTTIENLPAEGSGGGGSLSASSRAGVRQRIRKVLNREM 60

Query: 61  LISVALGQVLSLLICGIGLTSKYLSEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEEN 120
           LISVALGQVLSLLICGIGLTSKYLSEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEEN
Sbjct: 61  LISVALGQVLSLLICGIGLTSKYLSEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEEN 120

Query: 121 LLAILRRRWWKYMILGLIDLEANYLVVKAYQYTTLTSIQLLDCFVIPVVILLSWFFLLIR 180
           LLAILRRRWWKYMILGLIDLEANYLVVKAYQYTTLTSIQLLDCFVIPVVILLSWFFLLIR
Sbjct: 121 LLAILRRRWWKYMILGLIDLEANYLVVKAYQYTTLTSIQLLDCFVIPVVILLSWFFLLIR 180

Query: 181 YKAVHFIGIVVCILGMGCMVGADVLVGRHQGAGENKLVGDLLVLGGATLYGISNVWEEYI 240
           YKAVHFIGIVVCILGMGCMVGADVLVGRHQGAGENKLVGDLLVLGGATLYGISNVWEEYI
Sbjct: 181 YKAVHFIGIVVCILGMGCMVGADVLVGRHQGAGENKLVGDLLVLGGATLYGISNVWEEYI 240

Query: 241 IRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFM 300
           IRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFM
Sbjct: 241 IRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGFSACMFGLYSFM 300

Query: 301 PVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYSSTSTYI 360
           PVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYSSTSTYI
Sbjct: 301 PVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYSSTSTYI 360

Query: 361 AQDPRVYKQFRNPSGPVVDLPTTAQVEPSVTYTSLGQETEEEPHVRVA 408
           AQDPRVYKQFRNPSGPVVDLPTTAQVEPSVTYTSLGQETEEEPHVRVA
Sbjct: 361 AQDPRVYKQFRNPSGPVVDLPTTAQVEPSVTYTSLGQETEEEPHVRVA 408


>gi|31542943 solute carrier family 35, member F2 [Homo sapiens]
          Length = 374

 Score =  414 bits (1064), Expect = e-116
 Identities = 197/323 (60%), Positives = 256/323 (79%), Gaps = 1/323 (0%)

Query: 41  SASSRAGVRQRIR-KVLNREMLISVALGQVLSLLICGIGLTSKYLSEDFHANTPVFQSFL 99
           +A+  + + +RI+ K+    +L ++ALGQ+LSL ICG  +TS+YL+E +  NTP+ QSF+
Sbjct: 19  AAAEFSSLLRRIKGKLFTWNILKTIALGQMLSLCICGTAITSQYLAERYKVNTPMLQSFI 78

Query: 100 NYILLFLVYTTTLAVRQGEENLLAILRRRWWKYMILGLIDLEANYLVVKAYQYTTLTSIQ 159
           NY LLFL+YT  LA R G +NLL IL+R+WWKY++LGL D+EANY++V+AYQYTTLTS+Q
Sbjct: 79  NYCLLFLIYTVMLAFRSGSDNLLVILKRKWWKYILLGLADVEANYVIVRAYQYTTLTSVQ 138

Query: 160 LLDCFVIPVVILLSWFFLLIRYKAVHFIGIVVCILGMGCMVGADVLVGRHQGAGENKLVG 219
           LLDCF IPV++ LSWF L  RY+ +HFI + VC+LG+G MVGAD+L GR   +G + L+G
Sbjct: 139 LLDCFGIPVLMALSWFILHARYRVIHFIAVAVCLLGVGTMVGADILAGREDNSGSDVLIG 198

Query: 220 DLLVLGGATLYGISNVWEEYIIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWD 279
           D+LVL GA+LY ISNV EEYI++ LSR EFLGM+GLFG   SGIQL I+E+K++  + WD
Sbjct: 199 DILVLLGASLYAISNVCEEYIVKKLSRQEFLGMVGLFGTIISGIQLLIVEYKDIASIHWD 258

Query: 280 WQIGLLYVGFSACMFGLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLY 339
           W+I LL+V F+ CMF LYSFMP+VIK TSATSVNL +LTADLYSLF GLFLF YKFSGLY
Sbjct: 259 WKIALLFVAFALCMFCLYSFMPLVIKVTSATSVNLGILTADLYSLFVGLFLFGYKFSGLY 318

Query: 340 LLSFFTILIGLVLYSSTSTYIAQ 362
           +LSF  I++G +LY ST T  A+
Sbjct: 319 ILSFTVIMVGFILYCSTPTRTAE 341


>gi|27735127 solute carrier family 35, member F3 [Homo sapiens]
          Length = 490

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 50/226 (22%), Positives = 95/226 (42%), Gaps = 21/226 (9%)

Query: 136 GLIDLEANYLVVKAYQYTTLTSIQLLDCFVIPVVILLSWFFLLIRYKAVHFIGIVVCILG 195
           G++    NYL + A +    T + +L C     V LLSW  L  R+  V  +  ++ I G
Sbjct: 227 GVLWTLTNYLYLHAIKKINTTDVSVLFCCNKAFVFLLSWIVLRDRFMGVRIVAAILAIAG 286

Query: 196 MGCMVGADVLVGRHQGAGENKLVGDLLVLGGATLYGISNVWEEYIIRTLSRVE---FLGM 252
           +  M  AD       G   + ++G  LV+  A++  +  V  + ++ +    E   FL +
Sbjct: 287 IVMMTYAD-------GFHSHSVIGIALVVASASMSALYKVLFKLLLGSAKFGEAALFLSI 339

Query: 253 IGLFGAFFSGIQLAIMEHKELL------KVPWDWQIGLLYVGFSACMFGLYSFMPVVIKK 306
           +G+F   F      I+   ++        +PW    G L  GFS  +      +   I  
Sbjct: 340 LGVFNILFITCIPIILYFTKVEYWSSFDDIPW----GNL-CGFSVLLLTFNIVLNFGIAV 394

Query: 307 TSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVL 352
           T  T ++L ++ +   +     +     F+G+ +++   I +G +L
Sbjct: 395 TYPTLMSLGIVLSIPVNAVIDHYTSQIVFNGVRVIAIIIIGLGFLL 440


>gi|31542711 ANT2-binding protein [Homo sapiens]
          Length = 371

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 67/242 (27%), Positives = 105/242 (43%), Gaps = 27/242 (11%)

Query: 137 LIDLEANYLVVKAYQYTTLTSIQLLDCFVIPVVILLSWFFLLIRYKAVHFIGIVVCILGM 196
           L D+    L+  A   T+ +S Q+L   VI    L S  FL  R     ++GI+  I G+
Sbjct: 96  LCDMTGTSLMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLGRRLVLSQWLGILATIAGL 155

Query: 197 GCMVGADVLVGRH--QGAGENKLVGDLLVLGGATLYGISNVWEEYII--RTLSRVEFLGM 252
             +VG   L+ +H  Q      + GDLL++    +  I  V EE  +    +  +  +G 
Sbjct: 156 -VVVGLADLLSKHDSQHKLSEVITGDLLIIMAQIIVAIQMVLEEKFVYKHNVHPLRAVGT 214

Query: 253 IGLFGAFFSGIQLAIMEH----------KELLKVPWD--WQIG---LLYVGF--SACMFG 295
            GLFG     + L  M +          +  L+   D   Q+G   L+ V    +     
Sbjct: 215 EGLFGFVILSLLLVPMYYIPAGSFSGNPRGTLEDALDAFCQVGQQPLIAVALLGNISSIA 274

Query: 296 LYSFMPV-VIKKTSATS--VNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVL 352
            ++F  + V K+ SAT+  V  SL T  +++L   L L    F  L +L F  +LIG  L
Sbjct: 275 FFNFAGISVTKELSATTRMVLDSLRTVVIWAL--SLALGWEAFHALQILGFLILLIGTAL 332

Query: 353 YS 354
           Y+
Sbjct: 333 YN 334


>gi|122937311 solute carrier family 35, member F4 [Homo sapiens]
          Length = 521

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 49/209 (23%), Positives = 85/209 (40%), Gaps = 23/209 (11%)

Query: 117 GEENL-LAILRRRWWKYMILGLIDLEANYLVVKAYQYTTLTSIQLLDCFVIPVVILLSWF 175
           GE+ L L +  +R   + IL  +    NYL + A +  T T +  L C     V LLSW 
Sbjct: 239 GEDGLTLKLFLKRTAPFSILWTL---TNYLYLLALKKLTATDVSALFCCNKAFVFLLSWI 295

Query: 176 FLLIRYKAVHFIGIVVCILGMGCMVGADVLVGRHQGAGENKLVGDLLVLGGATLYGISNV 235
            L  R+  V  +  ++ I G+  M  AD           + ++G    +G A+   +  V
Sbjct: 296 VLKDRFMGVRIVAAIMAITGIVMMAYAD-------NFHADSIIGVAFAVGSASTSALYKV 348

Query: 236 WEEYIIRTLS---RVEFLGMIGLFGAFFSGIQLAIM-----EH-KELLKVPWDWQIGL-- 284
             +  + + +      F+  +G F   F      I+     EH      +PW    G+  
Sbjct: 349 LFKMFLGSANFGEAAHFVSTLGFFNLIFISFTPVILYFTKVEHWSSFAALPWGCLCGMAG 408

Query: 285 LYVGFSACM-FGLYSFMPVVIKKTSATSV 312
           L++ F+  +  G+    P++I   +  SV
Sbjct: 409 LWLAFNILVNVGVVLTYPILISIGTVLSV 437


>gi|27881499 solute carrier family 35, member C2 isoform a [Homo
           sapiens]
          Length = 365

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 73/323 (22%), Positives = 138/323 (42%), Gaps = 58/323 (17%)

Query: 64  VALGQVLSLLICGIGLT--SKYLSEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEENL 121
           + LG VL      IG+T  +K+L++ FH   P+F + L+  ++FL    + A+ Q   + 
Sbjct: 16  LTLGLVLLYYCFSIGITFYNKWLTKSFHF--PLFMTMLHLAVIFLFSALSRALVQCSSHR 73

Query: 122 LAILRRRWWKYMI------------LGLIDLEANYLVVKAYQYTTLTSIQLLDCF----- 164
             ++   W  Y+             +GL +    Y+ V  Y  T  +++  +  F     
Sbjct: 74  ARVVLS-WADYLRRVAPTALATALDVGLSNWSFLYVTVSLYTMTKSSAVLFILIFSLIFK 132

Query: 165 -------VIPVVILLSWFFLLIRYKAVHFIGIVVCILGMGCMVGADVLVGRHQGAGENKL 217
                  ++ VV+L++    +  YK+  F      + G   ++GA  + G      +   
Sbjct: 133 LEELRAALVLVVLLIAGGLFMFTYKSTQFN-----VEGFALVLGASFIGGIRWTLTQ--- 184

Query: 218 VGDLLVLGGATLYGISNVWEEYIIRTLSRVEFLGMIGLFGAFFSGIQLAIMEH------- 270
               ++L  A L G+ N  +      L  + FLG+  LF A F G+ L+  E        
Sbjct: 185 ----MLLQKAEL-GLQNPIDTMF--HLQPLMFLGLFPLF-AVFEGLHLSTSEKIFRFQDT 236

Query: 271 KELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFL 330
             LL+V     +G L++G     FGL     +++ +TS+ +++++ +  ++ +L     L
Sbjct: 237 GLLLRV-----LGSLFLG-GILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHL 290

Query: 331 FHYKFSGLYLLSFFTILIGLVLY 353
              + S L  L F   L G+ L+
Sbjct: 291 LGDQISLLNWLGFALCLSGISLH 313


>gi|21314776 solute carrier family 35, member C2 isoform a [Homo
           sapiens]
          Length = 365

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 73/323 (22%), Positives = 138/323 (42%), Gaps = 58/323 (17%)

Query: 64  VALGQVLSLLICGIGLT--SKYLSEDFHANTPVFQSFLNYILLFLVYTTTLAVRQGEENL 121
           + LG VL      IG+T  +K+L++ FH   P+F + L+  ++FL    + A+ Q   + 
Sbjct: 16  LTLGLVLLYYCFSIGITFYNKWLTKSFHF--PLFMTMLHLAVIFLFSALSRALVQCSSHR 73

Query: 122 LAILRRRWWKYMI------------LGLIDLEANYLVVKAYQYTTLTSIQLLDCF----- 164
             ++   W  Y+             +GL +    Y+ V  Y  T  +++  +  F     
Sbjct: 74  ARVVLS-WADYLRRVAPTALATALDVGLSNWSFLYVTVSLYTMTKSSAVLFILIFSLIFK 132

Query: 165 -------VIPVVILLSWFFLLIRYKAVHFIGIVVCILGMGCMVGADVLVGRHQGAGENKL 217
                  ++ VV+L++    +  YK+  F      + G   ++GA  + G      +   
Sbjct: 133 LEELRAALVLVVLLIAGGLFMFTYKSTQFN-----VEGFALVLGASFIGGIRWTLTQ--- 184

Query: 218 VGDLLVLGGATLYGISNVWEEYIIRTLSRVEFLGMIGLFGAFFSGIQLAIMEH------- 270
               ++L  A L G+ N  +      L  + FLG+  LF A F G+ L+  E        
Sbjct: 185 ----MLLQKAEL-GLQNPIDTMF--HLQPLMFLGLFPLF-AVFEGLHLSTSEKIFRFQDT 236

Query: 271 KELLKVPWDWQIGLLYVGFSACMFGLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFL 330
             LL+V     +G L++G     FGL     +++ +TS+ +++++ +  ++ +L     L
Sbjct: 237 GLLLRV-----LGSLFLG-GILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHL 290

Query: 331 FHYKFSGLYLLSFFTILIGLVLY 353
              + S L  L F   L G+ L+
Sbjct: 291 LGDQISLLNWLGFALCLSGISLH 313


>gi|19920317 cytoskeleton-associated protein 4 [Homo sapiens]
          Length = 602

 Score = 36.6 bits (83), Expect = 0.042
 Identities = 24/76 (31%), Positives = 31/76 (40%), Gaps = 5/76 (6%)

Query: 3   PPEQPQQQLQPPSPAPPNHVVTTIENLP-----AEGSGGGGSLSASSRAGVRQRIRKVLN 57
           PP  PQQ   PP+P P  H     +N         G GGGG  S+SS +          +
Sbjct: 36  PPPAPQQPPPPPAPHPQQHPQQHPQNQAHGKGGHRGGGGGGGKSSSSSSASAAAAAAAAS 95

Query: 58  REMLISVALGQVLSLL 73
                S  LG+ L+ L
Sbjct: 96  SSASCSRRLGRALNFL 111


>gi|87299628 biorientation of chromosomes in cell division 1-like
          [Homo sapiens]
          Length = 3051

 Score = 35.8 bits (81), Expect = 0.072
 Identities = 20/55 (36%), Positives = 25/55 (45%), Gaps = 10/55 (18%)

Query: 3  PPEQPQQQLQPPSPAPPNHVVTTIENLPAEGSGGGGSLSASSRAGVRQRIRKVLN 57
          PP  PQ Q QPP P P           P  G G GG+  A + AG  Q +  ++N
Sbjct: 15 PPPPPQPQPQPPPPPPG----------PGAGPGAGGAGGAGAGAGDPQLVAMIVN 59


>gi|134254450 patched isoform S [Homo sapiens]
          Length = 1296

 Score = 33.5 bits (75), Expect = 0.36
 Identities = 33/154 (21%), Positives = 62/154 (40%), Gaps = 15/154 (9%)

Query: 240  IIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGF-----SACMF 294
            ++  L  VE  GM+GL G   S + + I+     + V +   + L ++          + 
Sbjct: 907  MVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVL 966

Query: 295  GLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYS 354
             L      V+    +T + + +L    +      F+  Y F+ L +L+   +L GLVL  
Sbjct: 967  ALEHMFAPVLDGAVSTLLGVLMLAGSEFD-----FIVRYFFAVLAILTILGVLNGLVLLP 1021

Query: 355  STSTYIAQDPRVYKQFRNPSGPVVDLPTTAQVEP 388
               ++    P V     +P+  +  LPT +   P
Sbjct: 1022 VLLSFFGPYPEV-----SPANGLNRLPTPSPEPP 1050


>gi|134254435 patched isoform S [Homo sapiens]
          Length = 1296

 Score = 33.5 bits (75), Expect = 0.36
 Identities = 33/154 (21%), Positives = 62/154 (40%), Gaps = 15/154 (9%)

Query: 240  IIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGF-----SACMF 294
            ++  L  VE  GM+GL G   S + + I+     + V +   + L ++          + 
Sbjct: 907  MVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVL 966

Query: 295  GLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYS 354
             L      V+    +T + + +L    +      F+  Y F+ L +L+   +L GLVL  
Sbjct: 967  ALEHMFAPVLDGAVSTLLGVLMLAGSEFD-----FIVRYFFAVLAILTILGVLNGLVLLP 1021

Query: 355  STSTYIAQDPRVYKQFRNPSGPVVDLPTTAQVEP 388
               ++    P V     +P+  +  LPT +   P
Sbjct: 1022 VLLSFFGPYPEV-----SPANGLNRLPTPSPEPP 1050


>gi|134254468 patched isoform S [Homo sapiens]
          Length = 1296

 Score = 33.5 bits (75), Expect = 0.36
 Identities = 33/154 (21%), Positives = 62/154 (40%), Gaps = 15/154 (9%)

Query: 240  IIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGF-----SACMF 294
            ++  L  VE  GM+GL G   S + + I+     + V +   + L ++          + 
Sbjct: 907  MVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVL 966

Query: 295  GLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYS 354
             L      V+    +T + + +L    +      F+  Y F+ L +L+   +L GLVL  
Sbjct: 967  ALEHMFAPVLDGAVSTLLGVLMLAGSEFD-----FIVRYFFAVLAILTILGVLNGLVLLP 1021

Query: 355  STSTYIAQDPRVYKQFRNPSGPVVDLPTTAQVEP 388
               ++    P V     +P+  +  LPT +   P
Sbjct: 1022 VLLSFFGPYPEV-----SPANGLNRLPTPSPEPP 1050


>gi|134254452 patched isoform S [Homo sapiens]
          Length = 1296

 Score = 33.5 bits (75), Expect = 0.36
 Identities = 33/154 (21%), Positives = 62/154 (40%), Gaps = 15/154 (9%)

Query: 240  IIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGF-----SACMF 294
            ++  L  VE  GM+GL G   S + + I+     + V +   + L ++          + 
Sbjct: 907  MVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVL 966

Query: 295  GLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYS 354
             L      V+    +T + + +L    +      F+  Y F+ L +L+   +L GLVL  
Sbjct: 967  ALEHMFAPVLDGAVSTLLGVLMLAGSEFD-----FIVRYFFAVLAILTILGVLNGLVLLP 1021

Query: 355  STSTYIAQDPRVYKQFRNPSGPVVDLPTTAQVEP 388
               ++    P V     +P+  +  LPT +   P
Sbjct: 1022 VLLSFFGPYPEV-----SPANGLNRLPTPSPEPP 1050


>gi|134254432 patched isoform L' [Homo sapiens]
          Length = 1446

 Score = 33.5 bits (75), Expect = 0.36
 Identities = 33/154 (21%), Positives = 62/154 (40%), Gaps = 15/154 (9%)

Query: 240  IIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGF-----SACMF 294
            ++  L  VE  GM+GL G   S + + I+     + V +   + L ++          + 
Sbjct: 1057 MVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVL 1116

Query: 295  GLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYS 354
             L      V+    +T + + +L    +      F+  Y F+ L +L+   +L GLVL  
Sbjct: 1117 ALEHMFAPVLDGAVSTLLGVLMLAGSEFD-----FIVRYFFAVLAILTILGVLNGLVLLP 1171

Query: 355  STSTYIAQDPRVYKQFRNPSGPVVDLPTTAQVEP 388
               ++    P V     +P+  +  LPT +   P
Sbjct: 1172 VLLSFFGPYPEV-----SPANGLNRLPTPSPEPP 1200


>gi|134254466 patched isoform M [Homo sapiens]
          Length = 1381

 Score = 33.5 bits (75), Expect = 0.36
 Identities = 33/154 (21%), Positives = 62/154 (40%), Gaps = 15/154 (9%)

Query: 240  IIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGF-----SACMF 294
            ++  L  VE  GM+GL G   S + + I+     + V +   + L ++          + 
Sbjct: 992  MVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVL 1051

Query: 295  GLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYS 354
             L      V+    +T + + +L    +      F+  Y F+ L +L+   +L GLVL  
Sbjct: 1052 ALEHMFAPVLDGAVSTLLGVLMLAGSEFD-----FIVRYFFAVLAILTILGVLNGLVLLP 1106

Query: 355  STSTYIAQDPRVYKQFRNPSGPVVDLPTTAQVEP 388
               ++    P V     +P+  +  LPT +   P
Sbjct: 1107 VLLSFFGPYPEV-----SPANGLNRLPTPSPEPP 1135


>gi|134254446 patched isoform L [Homo sapiens]
          Length = 1447

 Score = 33.5 bits (75), Expect = 0.36
 Identities = 33/154 (21%), Positives = 62/154 (40%), Gaps = 15/154 (9%)

Query: 240  IIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYVGF-----SACMF 294
            ++  L  VE  GM+GL G   S + + I+     + V +   + L ++          + 
Sbjct: 1058 MVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVL 1117

Query: 295  GLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLYS 354
             L      V+    +T + + +L    +      F+  Y F+ L +L+   +L GLVL  
Sbjct: 1118 ALEHMFAPVLDGAVSTLLGVLMLAGSEFD-----FIVRYFFAVLAILTILGVLNGLVLLP 1172

Query: 355  STSTYIAQDPRVYKQFRNPSGPVVDLPTTAQVEP 388
               ++    P V     +P+  +  LPT +   P
Sbjct: 1173 VLLSFFGPYPEV-----SPANGLNRLPTPSPEPP 1201


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 33.1 bits (74), Expect = 0.47
 Identities = 15/37 (40%), Positives = 18/37 (48%)

Query: 3    PPEQPQQQLQPPSPAPPNHVVTTIENLPAEGSGGGGS 39
            PPE       PP+P  P H  T  +  P+  SG GGS
Sbjct: 1405 PPEGDTDPSTPPAPPTPPHPATPGDGFPSNDSGFGGS 1441


>gi|156564359 hypothetical protein LOC113278 [Homo sapiens]
          Length = 469

 Score = 32.3 bits (72), Expect = 0.79
 Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 4/87 (4%)

Query: 249 FLGMIGLFGAFFSG--IQLAIMEHKELLKVPWDWQIGLL--YVGFSACMFGLYSFMPVVI 304
           FLG++ + G  F G  + +A+M    LL+  W  ++ ++  +V FS C+  +   + VV+
Sbjct: 362 FLGVLSVLGTCFGGYNMAMAVMSPCPLLQGHWGGEVLIVASWVLFSGCLSYVKVMLGVVL 421

Query: 305 KKTSATSVNLSLLTADLYSLFCGLFLF 331
           +  S +++        L SL   L +F
Sbjct: 422 RDLSRSALLWCGAAVQLGSLLGALLMF 448


>gi|189491742 ataxin 7 isoform b [Homo sapiens]
          Length = 945

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 8/49 (16%)

Query: 3  PPEQPQQQLQPPSPAPPNHVVTTIENLPAEGSGGGGSLSASSRAGVRQR 51
          PP QPQ+Q  PP P             P +G  G  S SA++ A V +R
Sbjct: 41 PPPQPQRQQHPPPPPR--------RTRPEDGGPGAASTSAAAMATVGER 81


>gi|4506797 ataxin 7 isoform a [Homo sapiens]
          Length = 892

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 8/49 (16%)

Query: 3  PPEQPQQQLQPPSPAPPNHVVTTIENLPAEGSGGGGSLSASSRAGVRQR 51
          PP QPQ+Q  PP P             P +G  G  S SA++ A V +R
Sbjct: 41 PPPQPQRQQHPPPPPR--------RTRPEDGGPGAASTSAAAMATVGER 81


>gi|239752866 PREDICTED: similar to hCG1997308 [Homo sapiens]
          Length = 173

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 1   MIPPEQPQQQLQPPSPAPPNHVVTTIENLPAEGSGG-GGSLSASSRAGVRQRIR 53
           + PP  P  Q+ P +P P +H+  T E       G  G S+  SS+  V  R R
Sbjct: 64  LTPPPVPTLQVAPEAPCPQSHLSFTSEGSSGTSRGATGKSMGHSSQRPVSSRAR 117


>gi|239747418 PREDICTED: hypothetical protein XP_002346694 [Homo
           sapiens]
          Length = 173

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 1   MIPPEQPQQQLQPPSPAPPNHVVTTIENLPAEGSGG-GGSLSASSRAGVRQRIR 53
           + PP  P  Q+ P +P P +H+  T E       G  G S+  SS+  V  R R
Sbjct: 64  LTPPPVPTLQVAPEAPCPQSHLSFTSEGSSGTSRGATGKSMGHSSQRPVSSRAR 117


>gi|239741243 PREDICTED: hypothetical protein XP_002342142 [Homo
           sapiens]
          Length = 173

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 1   MIPPEQPQQQLQPPSPAPPNHVVTTIENLPAEGSGG-GGSLSASSRAGVRQRIR 53
           + PP  P  Q+ P +P P +H+  T E       G  G S+  SS+  V  R R
Sbjct: 64  LTPPPVPTLQVAPEAPCPQSHLSFTSEGSSGTSRGATGKSMGHSSQRPVSSRAR 117


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 12/17 (70%), Positives = 12/17 (70%)

Query: 3   PPEQPQQQLQPPSPAPP 19
           PP  PQQQ QPP P PP
Sbjct: 766 PPPPPQQQQQPPPPPPP 782


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
          potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 19/45 (42%), Positives = 20/45 (44%), Gaps = 10/45 (22%)

Query: 3  PPEQPQQQLQP---------PSPAPPNHVVTTIENLPAEGSGGGG 38
          PP  PQQQ  P         P PAPP H     E LP E +  GG
Sbjct: 27 PPAPPQQQPPPPPPPAPPPGPGPAPPQH-PPRAEALPPEAADEGG 70


>gi|52145305 patched 2 [Homo sapiens]
          Length = 1203

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 30/138 (21%), Positives = 57/138 (41%), Gaps = 12/138 (8%)

Query: 240  IIRTLSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKVPWDWQIGLLYV------GFSACM 293
            ++  +  VE  G++G  G   S I + I+     + V +   + L ++         A  
Sbjct: 994  LVLAMMTVELFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTTQGSRNLRAAH 1053

Query: 294  FGLYSFMPVVIKKTSATSVNLSLLTADLYSLFCGLFLFHYKFSGLYLLSFFTILIGLVLY 353
               ++F PV     S T + L +L    +      F+  Y F+ L +L+   +L GLVL 
Sbjct: 1054 ALEHTFAPVTDGAIS-TLLGLLMLAGSHFD-----FIVRYFFAALTVLTLLGLLHGLVLL 1107

Query: 354  SSTSTYIAQDPRVYKQFR 371
                + +   P V + ++
Sbjct: 1108 PVLLSILGPPPEVIQMYK 1125


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 16/48 (33%), Positives = 22/48 (45%), Gaps = 3/48 (6%)

Query: 3   PPEQPQQQLQPPSPAPPNHVVTTIENLPAE---GSGGGGSLSASSRAG 47
           PP  P  +L+  SP+PP  +      LP     G+GGGG  +     G
Sbjct: 65  PPAAPADRLRAESPSPPRLLAAHCALLPKPGFLGAGGGGGGTGGGHGG 112


>gi|13128980 proline rich 14 [Homo sapiens]
          Length = 585

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 1/45 (2%)

Query: 7   PQQQLQPPSPAPPNHVVTTIENLPAEGSGGG-GSLSASSRAGVRQ 50
           P +  QPP P+PP  +   I    AE SG   G+ S S R  +RQ
Sbjct: 267 PNKTPQPPPPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQ 311


>gi|21687252 zinc finger protein 296 [Homo sapiens]
          Length = 475

 Score = 30.4 bits (67), Expect = 3.0
 Identities = 17/55 (30%), Positives = 24/55 (43%), Gaps = 9/55 (16%)

Query: 2   IPPEQP------QQQLQPPSPAPPNHVVTTIENLPAEGSGGGGSLSASSRAGVRQ 50
           +PP+ P      Q+Q     P P  H       LP  G  G G   A++ AGV++
Sbjct: 284 VPPQSPLMADTSQEQASAAPPEPAVHAAAPTSTLPCSGGEGAG---AAATAGVQE 335


>gi|5453666 G protein-coupled receptor 19 [Homo sapiens]
          Length = 415

 Score = 30.4 bits (67), Expect = 3.0
 Identities = 14/43 (32%), Positives = 25/43 (58%)

Query: 139 DLEANYLVVKAYQYTTLTSIQLLDCFVIPVVILLSWFFLLIRY 181
           D   NY +  +++ T  T I  L  FVIP V+++ ++  +I+Y
Sbjct: 207 DSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVLIILFYQKVIKY 249


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.142    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,015,531
Number of Sequences: 37866
Number of extensions: 666396
Number of successful extensions: 5293
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 5083
Number of HSP's gapped (non-prelim): 218
length of query: 408
length of database: 18,247,518
effective HSP length: 105
effective length of query: 303
effective length of database: 14,271,588
effective search space: 4324291164
effective search space used: 4324291164
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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