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Search of human proteins with 188497716
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188497716 catenin, alpha 3 [Homo sapiens]
(895 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188497718 catenin, alpha 3 [Homo sapiens] 1730 0.0
gi|188497716 catenin, alpha 3 [Homo sapiens] 1730 0.0
gi|55770846 catenin, alpha 2 [Homo sapiens] 1077 0.0
gi|55770844 catenin, alpha 1 [Homo sapiens] 1044 0.0
gi|4507877 vinculin isoform VCL [Homo sapiens] 173 7e-43
gi|4503129 catenin, alpha-like 1 [Homo sapiens] 145 2e-34
gi|7669550 vinculin isoform meta-VCL [Homo sapiens] 107 4e-23
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 47 1e-04
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 47 1e-04
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 47 1e-04
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 47 1e-04
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 43 0.001
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 42 0.003
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 40 0.010
gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens] 38 0.037
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 37 0.063
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 37 0.082
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 36 0.14
gi|55770834 centromere protein F [Homo sapiens] 36 0.14
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 36 0.18
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 35 0.31
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 35 0.41
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 34 0.53
gi|110611218 ribosome binding protein 1 [Homo sapiens] 34 0.69
gi|110611220 ribosome binding protein 1 [Homo sapiens] 34 0.69
gi|39725952 angiogenic factor VG5Q [Homo sapiens] 33 0.91
gi|33946313 ninein isoform 4 [Homo sapiens] 33 0.91
gi|33946321 ninein isoform 5 [Homo sapiens] 33 0.91
gi|148536871 ninein isoform 1 [Homo sapiens] 33 0.91
gi|148536869 ninein isoform 2 [Homo sapiens] 33 0.91
>gi|188497718 catenin, alpha 3 [Homo sapiens]
Length = 895
Score = 1730 bits (4481), Expect = 0.0
Identities = 895/895 (100%), Positives = 895/895 (100%)
Query: 1 MSAETPITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLA 60
MSAETPITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLA
Sbjct: 1 MSAETPITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLA 60
Query: 61 SVEEATWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREA 120
SVEEATWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREA
Sbjct: 61 SVEEATWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREA 120
Query: 121 VVQAARALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKE 180
VVQAARALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKE
Sbjct: 121 VVQAARALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKE 180
Query: 181 LENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDT 240
LENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDT
Sbjct: 181 LENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDT 240
Query: 241 VCEEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSL 300
VCEEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSL
Sbjct: 241 VCEEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSL 300
Query: 301 EKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLN 360
EKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLN
Sbjct: 301 EKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLN 360
Query: 361 IALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFHE 420
IALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFHE
Sbjct: 361 IALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFHE 420
Query: 421 HTSRLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAVKNTME 480
HTSRLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAVKNTME
Sbjct: 421 HTSRLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAVKNTME 480
Query: 481 MYKRTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAI 540
MYKRTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAI
Sbjct: 481 MYKRTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAI 540
Query: 541 RGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALSKSSLNV 600
RGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALSKSSLNV
Sbjct: 541 RGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALSKSSLNV 600
Query: 601 LDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEEHEVRSHTSIQTEGKTDRA 660
LDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEEHEVRSHTSIQTEGKTDRA
Sbjct: 601 LDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEEHEVRSHTSIQTEGKTDRA 660
Query: 661 KMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFTR 720
KMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFTR
Sbjct: 661 KMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFTR 720
Query: 721 GKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSHQLK 780
GKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSHQLK
Sbjct: 721 GKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSHQLK 780
Query: 781 ICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSPAG 840
ICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSPAG
Sbjct: 781 ICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSPAG 840
Query: 841 PRHPVVMWRMKAPAKKPLIKREKPEETCAAVRRGSAKKKIHPLQVMSEFRGRQIY 895
PRHPVVMWRMKAPAKKPLIKREKPEETCAAVRRGSAKKKIHPLQVMSEFRGRQIY
Sbjct: 841 PRHPVVMWRMKAPAKKPLIKREKPEETCAAVRRGSAKKKIHPLQVMSEFRGRQIY 895
>gi|188497716 catenin, alpha 3 [Homo sapiens]
Length = 895
Score = 1730 bits (4481), Expect = 0.0
Identities = 895/895 (100%), Positives = 895/895 (100%)
Query: 1 MSAETPITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLA 60
MSAETPITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLA
Sbjct: 1 MSAETPITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLA 60
Query: 61 SVEEATWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREA 120
SVEEATWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREA
Sbjct: 61 SVEEATWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREA 120
Query: 121 VVQAARALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKE 180
VVQAARALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKE
Sbjct: 121 VVQAARALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKE 180
Query: 181 LENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDT 240
LENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDT
Sbjct: 181 LENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDT 240
Query: 241 VCEEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSL 300
VCEEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSL
Sbjct: 241 VCEEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSL 300
Query: 301 EKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLN 360
EKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLN
Sbjct: 301 EKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLN 360
Query: 361 IALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFHE 420
IALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFHE
Sbjct: 361 IALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFHE 420
Query: 421 HTSRLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAVKNTME 480
HTSRLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAVKNTME
Sbjct: 421 HTSRLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAVKNTME 480
Query: 481 MYKRTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAI 540
MYKRTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAI
Sbjct: 481 MYKRTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAI 540
Query: 541 RGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALSKSSLNV 600
RGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALSKSSLNV
Sbjct: 541 RGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALSKSSLNV 600
Query: 601 LDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEEHEVRSHTSIQTEGKTDRA 660
LDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEEHEVRSHTSIQTEGKTDRA
Sbjct: 601 LDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEEHEVRSHTSIQTEGKTDRA 660
Query: 661 KMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFTR 720
KMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFTR
Sbjct: 661 KMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFTR 720
Query: 721 GKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSHQLK 780
GKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSHQLK
Sbjct: 721 GKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSHQLK 780
Query: 781 ICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSPAG 840
ICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSPAG
Sbjct: 781 ICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSPAG 840
Query: 841 PRHPVVMWRMKAPAKKPLIKREKPEETCAAVRRGSAKKKIHPLQVMSEFRGRQIY 895
PRHPVVMWRMKAPAKKPLIKREKPEETCAAVRRGSAKKKIHPLQVMSEFRGRQIY
Sbjct: 841 PRHPVVMWRMKAPAKKPLIKREKPEETCAAVRRGSAKKKIHPLQVMSEFRGRQIY 895
>gi|55770846 catenin, alpha 2 [Homo sapiens]
Length = 905
Score = 1077 bits (2784), Expect = 0.0
Identities = 549/903 (60%), Positives = 704/903 (77%), Gaps = 19/903 (2%)
Query: 2 SAETPITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNCP-QNPSSRKKGRSKRASVLLA 60
SA +PI L DP+ L+++T TVE+LLEPL+ QVTTLVN + PS +KKGRSK+A VL A
Sbjct: 3 SATSPIILKWDPKSLEIRTLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVLAA 62
Query: 61 SVEEATWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREA 120
SVE+AT N L+KGE+IA+E+ LK+EL A++E+VRK+ E +++++ F DDPC KR
Sbjct: 63 SVEQATQNFLEKGEQIAKESQDLKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKRGT 122
Query: 121 VVQAARALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKE 180
+V+AARALL+AVTRLLILADM DVM LL H+ + E++KN N+ DL +++ GKE
Sbjct: 123 MVRAARALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFGKE 182
Query: 181 LENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDT 240
+ L+Y+A +RQQ+LK P+ RDE+A AR +LK+N+ +L++ A L H DVA+ +A++D
Sbjct: 183 MVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRDY 242
Query: 241 VCEEIQNALNVISNASQGIQNMTTPPEPQA------ATLGSALDELENLIVLNPLTVTEE 294
V +++Q A+ ISNA+Q T P +A L +AL+E +N I+L+P+T +E
Sbjct: 243 VFKQVQEAIAGISNAAQA-----TSPTDEAKGHTGIGELAAALNEFDNKIILDPMTFSEA 297
Query: 295 EIRPSLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKE 354
RPSLE+RLE+IISGAAL+ADSSCTRD RERI+AECNA+RQALQDLLSEYMNN G+KE
Sbjct: 298 RFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKE 357
Query: 355 RSNTLNIALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEY 414
+ + LNIA+D M KKTRDLRRQLRKA++DH+SDSFL+T VPLLVLIEAAK+G EKE+KEY
Sbjct: 358 KGDPLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEY 417
Query: 415 AAIFHEHTSRLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQA 474
A +F EH ++LVEVANLACS+S NE+G+K+V++AA +++LCPQ+INAAL LAARP+S+
Sbjct: 418 AQVFREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKV 477
Query: 475 VKNTMEMYKRTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLD 534
++ M+++K WE + VLTEAVDDITS+DDFL+VSE+HILEDVNKC+IAL++ D D LD
Sbjct: 478 AQDNMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLD 537
Query: 535 RAAGAIRGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALS 594
R AGAIRGRAARV HI+ EM++YE G YTE V+ L+ TV+P F QV VA+EALS
Sbjct: 538 RTAGAIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALS 597
Query: 595 KSSLNVLDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLE-EEHEVRSHTSIQT 653
+ ++N+F+D S+ +YD + DIR +V+MIRTPEELED SD E E+++VRS TS+QT
Sbjct: 598 ANVPQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQEDYDVRSRTSVQT 657
Query: 654 E------GKTDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKN 707
E G++ RA M QLP+ EK KIAEQV F + KSKLDAE+ WDD+ NDIIVLAK
Sbjct: 658 EDDQLIAGQSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQ 717
Query: 708 MCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLA 767
MCMIMMEMTDFTRGKGPLK+T+DVI AAK I+E+GSRMD LAR +A+QCPD +CKQDLLA
Sbjct: 718 MCMIMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLLA 777
Query: 768 YLEQIKFYSHQLKICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYI 827
YL++I Y HQL ICS+VKAE+QNLGGELI+S LDS TSLIQAAKNLMNAVV TVK SY+
Sbjct: 778 YLQRIALYCHQLNICSKVKAEVQNLGGELIVSGLDSATSLIQAAKNLMNAVVLTVKASYV 837
Query: 828 ASTKIIRIQSPAGPRHPVVMWRMKAPAKKPLIKREKPEETCAAVRRGSAKKKIHPLQVMS 887
ASTK ++ A PVV W+MKAP KKPL+KREKPEE VRRGS KK I P+Q +S
Sbjct: 838 ASTKYQKVYGTAAVNSPVVSWKMKAPEKKPLVKREKPEEFQTRVRRGSQKKHISPVQALS 897
Query: 888 EFR 890
EF+
Sbjct: 898 EFK 900
>gi|55770844 catenin, alpha 1 [Homo sapiens]
Length = 906
Score = 1044 bits (2699), Expect = 0.0
Identities = 531/893 (59%), Positives = 684/893 (76%), Gaps = 9/893 (1%)
Query: 7 ITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNC-PQNPSSRKKGRSKRASVLLASVEEA 65
I DP+ L+++T VE+LLEPL+ QVTTLVN + PS++K+GRSK+A VL ASVE+A
Sbjct: 9 INFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQA 68
Query: 66 TWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAA 125
T N L+KG+KIA+E+ LK+EL A++E+VRK+ + +K +A F DDPC KR +V+AA
Sbjct: 69 TENFLEKGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAA 128
Query: 126 RALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKELENLD 185
RALL+AVTRLLILADM DV LL + + L+N N+ DL Y+ L E++ L+
Sbjct: 129 RALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLN 188
Query: 186 YLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVCEEI 245
+A KRQQ+LK RD++A AR L++N P+L++ ACL+H DVA+ KA++D + +++
Sbjct: 189 IMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQL 248
Query: 246 QNALNVISNASQGIQNMTTPPEPQAA--TLGSALDELENLIVLNPLTVTEEEIRPSLEKR 303
Q A+ ISNA+Q + L AL+ + I+++PL+ +EE RPSLE+R
Sbjct: 249 QQAVTGISNAAQATASDDASQHQGGGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEER 308
Query: 304 LEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLNIAL 363
LE+IISGAAL+ADSSCTRD RERI+AECNA+RQALQDLLSEYM NAG+KERS+ LN A+
Sbjct: 309 LESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKERSDALNSAI 368
Query: 364 DNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFHEHTS 423
D M KKTRDLRRQLRKA++DHVSDSFL+T VPLLVLIEAAKNG EKE+KEYA +F EH +
Sbjct: 369 DKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHAN 428
Query: 424 RLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAVKNTMEMYK 483
+L+EVANLACS+S NE+G+K+V+++A+ LE LCPQ+INAALALAA+P+S+ + M+++K
Sbjct: 429 KLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDLFK 488
Query: 484 RTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAIRGR 543
WE + VLT+AVDDITSIDDFLAVSE+HILEDVNKC+IAL+++D D LDR AGAIRGR
Sbjct: 489 EQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGR 548
Query: 544 AARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALSKSSLNVLDD 603
AARV H+VT EMD+YEPG YTE V+ L++TV+P F QV A+EALS +D+
Sbjct: 549 AARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDE 608
Query: 604 NQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEEHEVRSHTSIQTE------GKT 657
N+F+D S+ +YD I DIR +V+MIRTPEEL+D E+ +VRS TS+QTE G++
Sbjct: 609 NEFIDASRLVYDGIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTEDDQLIAGQS 668
Query: 658 DRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTD 717
RA M QLP+ +K KIAEQVA F++ KSKLDAE+ WDD+ NDIIVLAK MCMIMMEMTD
Sbjct: 669 ARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTD 728
Query: 718 FTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSH 777
FTRGKGPLK+T+DVI AAK I+E+GSRMD L R IA+ CPD +CKQDLLAYL++I Y H
Sbjct: 729 FTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALYCH 788
Query: 778 QLKICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQS 837
QL ICS+VKAE+QNLGGEL++S +DS SLIQAAKNLMNAVVQTVK SY+ASTK + Q
Sbjct: 789 QLNICSKVKAEVQNLGGELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVASTKYQKSQG 848
Query: 838 PAGPRHPVVMWRMKAPAKKPLIKREKPEETCAAVRRGSAKKKIHPLQVMSEFR 890
A P V W+MKAP KKPL+KREK +ET ++R S KK ++P+Q +SEF+
Sbjct: 849 MASLNLPAVSWKMKAPEKKPLVKREKQDETQTKIKRASQKKHVNPVQALSEFK 901
>gi|4507877 vinculin isoform VCL [Homo sapiens]
Length = 1066
Score = 173 bits (438), Expect = 7e-43
Identities = 170/665 (25%), Positives = 282/665 (42%), Gaps = 48/665 (7%)
Query: 198 PNQRDEIAGARASL----------KENSPLLHSICSACLEHSDVASLKASKDTVCEEIQN 247
P ++I GA A KE +L S+ S +A L+ E +
Sbjct: 402 PEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARA 461
Query: 248 ALNVISNASQGIQNMT------TPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSLE 301
++ A Q +Q T + P A L +++ + I NP TV + + +
Sbjct: 462 LAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWID-NP-TVDDRGVGQAAI 519
Query: 302 KRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLNI 361
+ L A G L ++ +R+ ++A+C+ + Q L G+ ++ L
Sbjct: 520 RGLVA--EGHRL---ANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALAS 574
Query: 362 ALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKN-----GREKEIKEYAA 416
L + K DL+ ++++A+ VSD F DTT P+ +L AA RE+ E AA
Sbjct: 575 QLQDSLK---DLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAA 631
Query: 417 IFHEHTSRLVEVANLACSMST-NEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAV 475
F H+ +L A A ++ T N+ ++ ++ + L PQ+++AA L P +QA
Sbjct: 632 NFENHSGKLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAA 691
Query: 476 KNTMEMYKRTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDR 535
E K W +++ +T VD+ L SE I +D++KC +A+ + L
Sbjct: 692 YEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVA 751
Query: 536 AAGAIRGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALSK 595
A +I RA R+ + E+++ E + E V + L+ T+ P V +S
Sbjct: 752 GATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISP-MVMDAKAVAGNISD 810
Query: 596 SSLNVLDDNQFVDISKKIYDTIHDIRCSVMMIRT--PEELEDVSDLEEEHEVRSHTSIQT 653
L F+D +I + +R + P D+ L E+
Sbjct: 811 PGL----QKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLP 866
Query: 654 EGKTDRAKMTQLPEAEKEKIAEQVA------DFKKVKSKLDAEIEIWDDTSNDIIVLAKN 707
EG+ + PE + E+ EQ A +L E W NDII AK
Sbjct: 867 EGEVPPPRPPP-PEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKGNDIIAAAKR 925
Query: 708 MCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLA 767
M ++M EM+ RG K +I AK I+++ + LA+++A QC D + +LL
Sbjct: 926 MALLMAEMSRLVRGGSGTKRA--LIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQ 983
Query: 768 YLEQIKFYSHQLKICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYI 827
E+I S QLKI S VKA + + + L+ A+NLM +V +TV+ +
Sbjct: 984 VCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEA 1043
Query: 828 ASTKI 832
AS KI
Sbjct: 1044 ASIKI 1048
Score = 59.7 bits (143), Expect = 1e-08
Identities = 48/203 (23%), Positives = 93/203 (45%), Gaps = 3/203 (1%)
Query: 20 TFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLASVEEATWNLLDKGEKIAQ- 78
T T+E +LEP+ Q++ LV + K + + A+V+ A NL+ G++ Q
Sbjct: 6 TRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPV-AAVQAAVSNLVRVGKETVQT 64
Query: 79 -EATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAARALLAAVTRLLI 137
E +LK ++ + +V L +A+ DP +P R+ ++ +R +L+ + LL+
Sbjct: 65 TEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLL 124
Query: 138 LADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKELENLDYLAFKRQQDLKS 197
D +V +++ + V DL + LG + + + +RQQ+L
Sbjct: 125 TFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTH 184
Query: 198 PNQRDEIAGARASLKENSPLLHS 220
R + + ++KE P+L S
Sbjct: 185 QEHRVMLVNSMNTVKELLPVLIS 207
>gi|4503129 catenin, alpha-like 1 [Homo sapiens]
Length = 734
Score = 145 bits (366), Expect = 2e-34
Identities = 125/506 (24%), Positives = 233/506 (46%), Gaps = 28/506 (5%)
Query: 16 LQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLA-SVEEATWNLLDKGE 74
L+++T +VE+ L PL+ Q+TTL+N N ++K ++ +A + +V A + GE
Sbjct: 30 LEIKTRSVEQTLLPLVSQITTLINHKDN--TKKSDKTLQAIQRVGQAVNLAVGRFVKVGE 87
Query: 75 KIAQEATVLKDELTASLEEVRKESEALKVSAE-------RFTDDPCFLPKREAVVQAARA 127
IA E LK+E+ + E ++ E + + + V++AAR
Sbjct: 88 AIANENWDLKEEINIACIEAKQAGETIAALTDITNLNHLESDGQITIFTDKTGVIKAARL 147
Query: 128 LLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKELENLDYL 187
LL++VT++L+LAD + + ++ + T E L+ V + + + + + G E+ +L
Sbjct: 148 LLSSVTKVLLLADRVVIKQIITSRNKVLATMERLEKVNSFQEFVQIFSQFGNEMVEFAHL 207
Query: 188 AFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQN 247
+ RQ DLK ++ ++A ARA L++ + +L + CL H + S +K+ V + ++
Sbjct: 208 SGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKV 267
Query: 248 ALNVISNASQGIQNMTTPPEPQAATLGSALDELENL--IVLNPLTVTEE---EIRPSLEK 302
AL+ + + T +P T S++ + +N + E + + +L
Sbjct: 268 ALDKVI-------EIVTDCKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSV 320
Query: 303 RLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERS--NTLN 360
LE I+ DS+ T HRERI+ R LQ L+S ++ KK +S L
Sbjct: 321 TLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSKKTKSIAEELE 380
Query: 361 IALDNMCKKTRDLRRQLRKAIIDHVSD--SFLDTTVPLLVLIEAAKNGREKEIKEYAAIF 418
+++ + +L+++L +D + V L L G + + EYA
Sbjct: 381 LSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACKL 440
Query: 419 HEHTSRLVEVANLACSMSTNEDGIKIVKIAANH-LETLCPQIINAALALAARPKSQAVKN 477
E +LVE L +S E ++I I A + QII+AA L P S+ K
Sbjct: 441 SEQKEQLVETCRLLRHISGTEP-LEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKE 499
Query: 478 TMEMYKRTWENHIHVLTEAVDDITSI 503
++++ WE+ I ++ + +I +
Sbjct: 500 NLDVFCEAWESQISDMSTLLREINDV 525
Score = 62.4 bits (150), Expect = 2e-09
Identities = 44/162 (27%), Positives = 79/162 (48%), Gaps = 11/162 (6%)
Query: 666 PEAEKE-KIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFTRGKGP 724
P++E++ KIA+ + S D EIE W+D N+I+ +NM + + FTRG+GP
Sbjct: 557 PDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGP 616
Query: 725 LKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSHQLKICSQ 784
LK + D+I+ ++ + G ++ + + Q D K LL + ++ HQL+ +
Sbjct: 617 LKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDD-KLMLLLEINKLIPLCHQLQ--TV 673
Query: 785 VKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSY 826
K +QN V I +++M +VQ + + Y
Sbjct: 674 TKTSLQN-------KVFLKVDKCITKTRSMMALLVQLLSLCY 708
>gi|7669550 vinculin isoform meta-VCL [Homo sapiens]
Length = 1134
Score = 107 bits (268), Expect = 4e-23
Identities = 100/405 (24%), Positives = 176/405 (43%), Gaps = 32/405 (7%)
Query: 198 PNQRDEIAGARASL----------KENSPLLHSICSACLEHSDVASLKASKDTVCEEIQN 247
P ++I GA A KE +L S+ S +A L+ E +
Sbjct: 402 PEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARA 461
Query: 248 ALNVISNASQGIQNMT------TPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSLE 301
++ A Q +Q T + P A L +++ + I NP TV + + +
Sbjct: 462 LAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWID-NP-TVDDRGVGQAAI 519
Query: 302 KRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLNI 361
+ L A G L ++ +R+ ++A+C+ + Q L G+ ++ L
Sbjct: 520 RGLVA--EGHRL---ANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALAS 574
Query: 362 ALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKN-----GREKEIKEYAA 416
L + K DL+ ++++A+ VSD F DTT P+ +L AA RE+ E AA
Sbjct: 575 QLQDSLK---DLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAA 631
Query: 417 IFHEHTSRLVEVANLACSMST-NEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAV 475
F H+ +L A A ++ T N+ ++ ++ + L PQ+++AA L P +QA
Sbjct: 632 NFENHSGKLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAA 691
Query: 476 KNTMEMYKRTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDR 535
E K W +++ +T VD+ L SE I +D++KC +A+ + L
Sbjct: 692 YEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVA 751
Query: 536 AAGAIRGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIP 580
A +I RA R+ + E+++ E + E V + L+ T+ P
Sbjct: 752 GATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISP 796
Score = 78.2 bits (191), Expect = 3e-14
Identities = 51/146 (34%), Positives = 74/146 (50%), Gaps = 2/146 (1%)
Query: 687 LDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMD 746
L E W NDII AK M ++M EM+ RG K +I AK I+++ +
Sbjct: 973 LHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRA--LIQCAKDIAKASDEVT 1030
Query: 747 VLARQIANQCPDPSCKQDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIMSALDSVTS 806
LA+++A QC D + +LL E+I S QLKI S VKA + + +
Sbjct: 1031 RLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEM 1090
Query: 807 LIQAAKNLMNAVVQTVKMSYIASTKI 832
L+ A+NLM +V +TV+ + AS KI
Sbjct: 1091 LVHNAQNLMQSVKETVREAEAASIKI 1116
Score = 59.7 bits (143), Expect = 1e-08
Identities = 48/203 (23%), Positives = 93/203 (45%), Gaps = 3/203 (1%)
Query: 20 TFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLASVEEATWNLLDKGEKIAQ- 78
T T+E +LEP+ Q++ LV + K + + A+V+ A NL+ G++ Q
Sbjct: 6 TRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPV-AAVQAAVSNLVRVGKETVQT 64
Query: 79 -EATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAARALLAAVTRLLI 137
E +LK ++ + +V L +A+ DP +P R+ ++ +R +L+ + LL+
Sbjct: 65 TEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLL 124
Query: 138 LADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKELENLDYLAFKRQQDLKS 197
D +V +++ + V DL + LG + + + +RQQ+L
Sbjct: 125 TFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTH 184
Query: 198 PNQRDEIAGARASLKENSPLLHS 220
R + + ++KE P+L S
Sbjct: 185 QEHRVMLVNSMNTVKELLPVLIS 207
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 46.6 bits (109), Expect = 1e-04
Identities = 99/418 (23%), Positives = 166/418 (39%), Gaps = 61/418 (14%)
Query: 14 QDLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVL---LASVEEATWNLL 70
Q LQ++ T E ++ L ++ + + S +K +R S L LA EE NL
Sbjct: 967 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1026
Query: 71 ---DKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKR--EAVVQAA 125
+K E + E V + S +E+ K L+ A F + L + E +Q A
Sbjct: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1086
Query: 126 RALLAAVTRLLILADMI--------DVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKL 177
+ L L D I + L H+S Q +S + NK++ QK + L
Sbjct: 1087 KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK--RDL 1144
Query: 178 GKELENL-----DYL-AFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDV 231
G+ELE L D L + QQ+L++ +++ +A +E + +H+
Sbjct: 1145 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1204
Query: 232 ---------------ASLKASKDTVCEE---IQNALNVISNASQGIQNMTTPPEPQAATL 273
A+L +K T+ +E + L V+ A Q +++ E Q L
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1264
Query: 274 GS-------ALDELENLI--VLNPLTVTEEEIRPSLEKRLEAIISGAALLADSSCTRDLH 324
S A EL + + + N + + + K ++ A+L + T++L
Sbjct: 1265 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1324
Query: 325 RERIIAECNAI---------RQALQDLLSEYMNNAGKKERS-NTLNIALDNMCKKTRD 372
+E + N R +LQD L E M ER +TLNI L + KK +D
Sbjct: 1325 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382
Score = 31.2 bits (69), Expect = 4.5
Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 18/119 (15%)
Query: 612 KIYDTIHDIRCSVMMIRTPEELEDV-----SDLEEEHEVRSHTSIQTEGKTDRAKMTQLP 666
++Y ++R V + +ELE++ + LEEE + +Q E K +M L
Sbjct: 901 ELYAEAEEMR--VRLAAKKQELEEILHEMEARLEEEED--RGQQLQAERKKMAQQMLDLE 956
Query: 667 EA-EKEKIAEQVADFKKVKS-----KLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFT 719
E E+E+ A Q +KV + KL+ EI + DD +N L+K ++ ++D T
Sbjct: 957 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNK---LSKERKLLEERISDLT 1012
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 46.6 bits (109), Expect = 1e-04
Identities = 99/418 (23%), Positives = 166/418 (39%), Gaps = 61/418 (14%)
Query: 14 QDLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVL---LASVEEATWNLL 70
Q LQ++ T E ++ L ++ + + S +K +R S L LA EE NL
Sbjct: 974 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1033
Query: 71 ---DKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKR--EAVVQAA 125
+K E + E V + S +E+ K L+ A F + L + E +Q A
Sbjct: 1034 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1093
Query: 126 RALLAAVTRLLILADMI--------DVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKL 177
+ L L D I + L H+S Q +S + NK++ QK + L
Sbjct: 1094 KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK--RDL 1151
Query: 178 GKELENL-----DYL-AFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDV 231
G+ELE L D L + QQ+L++ +++ +A +E + +H+
Sbjct: 1152 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1211
Query: 232 ---------------ASLKASKDTVCEE---IQNALNVISNASQGIQNMTTPPEPQAATL 273
A+L +K T+ +E + L V+ A Q +++ E Q L
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1271
Query: 274 GS-------ALDELENLI--VLNPLTVTEEEIRPSLEKRLEAIISGAALLADSSCTRDLH 324
S A EL + + + N + + + K ++ A+L + T++L
Sbjct: 1272 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1331
Query: 325 RERIIAECNAI---------RQALQDLLSEYMNNAGKKERS-NTLNIALDNMCKKTRD 372
+E + N R +LQD L E M ER +TLNI L + KK +D
Sbjct: 1332 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389
Score = 31.2 bits (69), Expect = 4.5
Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 18/119 (15%)
Query: 612 KIYDTIHDIRCSVMMIRTPEELEDV-----SDLEEEHEVRSHTSIQTEGKTDRAKMTQLP 666
++Y ++R V + +ELE++ + LEEE + +Q E K +M L
Sbjct: 908 ELYAEAEEMR--VRLAAKKQELEEILHEMEARLEEEED--RGQQLQAERKKMAQQMLDLE 963
Query: 667 EA-EKEKIAEQVADFKKVKS-----KLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFT 719
E E+E+ A Q +KV + KL+ EI + DD +N L+K ++ ++D T
Sbjct: 964 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNK---LSKERKLLEERISDLT 1019
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 46.6 bits (109), Expect = 1e-04
Identities = 99/418 (23%), Positives = 166/418 (39%), Gaps = 61/418 (14%)
Query: 14 QDLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVL---LASVEEATWNLL 70
Q LQ++ T E ++ L ++ + + S +K +R S L LA EE NL
Sbjct: 974 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1033
Query: 71 ---DKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKR--EAVVQAA 125
+K E + E V + S +E+ K L+ A F + L + E +Q A
Sbjct: 1034 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1093
Query: 126 RALLAAVTRLLILADMI--------DVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKL 177
+ L L D I + L H+S Q +S + NK++ QK + L
Sbjct: 1094 KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK--RDL 1151
Query: 178 GKELENL-----DYL-AFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDV 231
G+ELE L D L + QQ+L++ +++ +A +E + +H+
Sbjct: 1152 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1211
Query: 232 ---------------ASLKASKDTVCEE---IQNALNVISNASQGIQNMTTPPEPQAATL 273
A+L +K T+ +E + L V+ A Q +++ E Q L
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1271
Query: 274 GS-------ALDELENLI--VLNPLTVTEEEIRPSLEKRLEAIISGAALLADSSCTRDLH 324
S A EL + + + N + + + K ++ A+L + T++L
Sbjct: 1272 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1331
Query: 325 RERIIAECNAI---------RQALQDLLSEYMNNAGKKERS-NTLNIALDNMCKKTRD 372
+E + N R +LQD L E M ER +TLNI L + KK +D
Sbjct: 1332 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389
Score = 31.2 bits (69), Expect = 4.5
Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 18/119 (15%)
Query: 612 KIYDTIHDIRCSVMMIRTPEELEDV-----SDLEEEHEVRSHTSIQTEGKTDRAKMTQLP 666
++Y ++R V + +ELE++ + LEEE + +Q E K +M L
Sbjct: 908 ELYAEAEEMR--VRLAAKKQELEEILHEMEARLEEEED--RGQQLQAERKKMAQQMLDLE 963
Query: 667 EA-EKEKIAEQVADFKKVKS-----KLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFT 719
E E+E+ A Q +KV + KL+ EI + DD +N L+K ++ ++D T
Sbjct: 964 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNK---LSKERKLLEERISDLT 1019
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 46.6 bits (109), Expect = 1e-04
Identities = 99/418 (23%), Positives = 166/418 (39%), Gaps = 61/418 (14%)
Query: 14 QDLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVL---LASVEEATWNLL 70
Q LQ++ T E ++ L ++ + + S +K +R S L LA EE NL
Sbjct: 967 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1026
Query: 71 ---DKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKR--EAVVQAA 125
+K E + E V + S +E+ K L+ A F + L + E +Q A
Sbjct: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1086
Query: 126 RALLAAVTRLLILADMI--------DVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKL 177
+ L L D I + L H+S Q +S + NK++ QK + L
Sbjct: 1087 KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK--RDL 1144
Query: 178 GKELENL-----DYL-AFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDV 231
G+ELE L D L + QQ+L++ +++ +A +E + +H+
Sbjct: 1145 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1204
Query: 232 ---------------ASLKASKDTVCEE---IQNALNVISNASQGIQNMTTPPEPQAATL 273
A+L +K T+ +E + L V+ A Q +++ E Q L
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1264
Query: 274 GS-------ALDELENLI--VLNPLTVTEEEIRPSLEKRLEAIISGAALLADSSCTRDLH 324
S A EL + + + N + + + K ++ A+L + T++L
Sbjct: 1265 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1324
Query: 325 RERIIAECNAI---------RQALQDLLSEYMNNAGKKERS-NTLNIALDNMCKKTRD 372
+E + N R +LQD L E M ER +TLNI L + KK +D
Sbjct: 1325 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382
Score = 31.2 bits (69), Expect = 4.5
Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 18/119 (15%)
Query: 612 KIYDTIHDIRCSVMMIRTPEELEDV-----SDLEEEHEVRSHTSIQTEGKTDRAKMTQLP 666
++Y ++R V + +ELE++ + LEEE + +Q E K +M L
Sbjct: 901 ELYAEAEEMR--VRLAAKKQELEEILHEMEARLEEEED--RGQQLQAERKKMAQQMLDLE 956
Query: 667 EA-EKEKIAEQVADFKKVKS-----KLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFT 719
E E+E+ A Q +KV + KL+ EI + DD +N L+K ++ ++D T
Sbjct: 957 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNK---LSKERKLLEERISDLT 1012
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 43.1 bits (100), Expect = 0.001
Identities = 62/289 (21%), Positives = 126/289 (43%), Gaps = 28/289 (9%)
Query: 126 RALLAAVTRLLILADMIDV--MCLLQHVSAFQRTFESLK-NVANKSDLQKTYQKLGKELE 182
+ + AA TRL L D I+ +L+ F++ E+++ +++ Y++L L+
Sbjct: 444 KKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQ 503
Query: 183 NLDYLAFKRQQ----DLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASK 238
++ L RQ+ +L+ Q+ EIAG + +K+ + S+ S +HS + + K+ K
Sbjct: 504 LVNKL---RQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGK 560
Query: 239 DTVCEEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRP 298
+ L++++ Q +++ + A + +LE + + E
Sbjct: 561 -------EQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANE----- 608
Query: 299 SLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNT 358
+L+K LE +ISG L + T + EC +R + LL ++++
Sbjct: 609 ALKKDLEGVISG---LQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEI 665
Query: 359 LNIALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGR 407
+ + +NM K+ +L L++ H ++ L T L EA R
Sbjct: 666 VAMDAENMRKELAELESALQE---QHEVNASLQQTQGDLSAYEAELEAR 711
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 41.6 bits (96), Expect = 0.003
Identities = 160/761 (21%), Positives = 300/761 (39%), Gaps = 126/761 (16%)
Query: 24 EKLLEPLIIQVTT-LVNCPQNPSSRKKGRSKRASVLLASVEEATWNLLDKGEKIAQEATV 82
+KL+E I + ++ L + + K R+K+ V+++ +EE L K EK QE
Sbjct: 1001 KKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQ-EVMISDLEER----LKKEEKTRQELEK 1055
Query: 83 LKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAARALLAAVTRLLILADMI 142
K +L +++ + L+ + L K+E +Q A L L + +
Sbjct: 1056 AKRKLDGETTDLQDQIAELQAQIDELKLQ---LAKKEEELQGA--LARGDDETLHKNNAL 1110
Query: 143 DVMCLLQ-HVSAFQRTFESLKNVANKS-----DLQKTYQKLGKELEN-LDYLAFKRQQDL 195
V+ LQ ++ Q FES K NK+ DL + + L ELE+ LD A QQ+L
Sbjct: 1111 KVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTA--AQQEL 1168
Query: 196 KSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQNALNVISNA 255
++ ++ E+A + +L+E + H + +L + + E+++ A +N
Sbjct: 1169 RTKREQ-EVAELKKALEEETK-NHEAQIQDMRQRHATAL----EELSEQLEQAKRFKANL 1222
Query: 256 SQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSLEKRLEAIISGAALLA 315
+ Q + T + A + VL + E R L+ +++
Sbjct: 1223 EKNKQGLETDNKELAC----------EVKVLQQVKAESEHKRKKLDAQVQ---------- 1262
Query: 316 DSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLNIALDNMCKKTRD--- 372
+LH + ++E + +R L + S+ N S L A K +D
Sbjct: 1263 ------ELHAK--VSEGDRLRVELAEKASKLQNELDNV--STLLEEAEKKGIKFAKDAAS 1312
Query: 373 LRRQLR--KAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFHEHTSRLVEVAN 430
L QL+ + ++ + L+ + + L E + +E++ +E A + L +
Sbjct: 1313 LESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQ 1372
Query: 431 LACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAVK-NTMEMYKRTWENH 489
LA + +D + ++ LE +++ A AL+ R + +A+ + +E K +
Sbjct: 1373 LADTKKKVDDDLGTIE----SLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQE 1428
Query: 490 IHVLTEAVDDITSIDDFLAVSESHI--LEDVNKCIIALRDQDADNLDRAAGAIRGRAARV 547
+ LT +D + L + L K I A ++ D + A +A +
Sbjct: 1429 LDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSL 1488
Query: 548 AHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALSKSSLNVLDDNQFV 607
A + +++ E EF Q N L A + ++ D
Sbjct: 1489 ARALEEALEAKE---------------------EFERQ-NKQLRADMEDLMSSKD----- 1521
Query: 608 DISKKIYDTIHDIRC---SVMMIRTP-EELEDVSDLEEEHEVRSHTSIQT---------- 653
D+ K +++ R V +RT EELED E+ ++R ++Q
Sbjct: 1522 DVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQ 1581
Query: 654 -------EGKTDRAKMTQLPEAEKEKIAEQ----VADFKKVK---SKLDAEIEIWDDTSN 699
E K K + EAE E +Q VA KK++ L+A+IE + +
Sbjct: 1582 TRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARD 1641
Query: 700 DIIVLAKNMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISE 740
++I K + + +M D+ R + + D I+A SE
Sbjct: 1642 EVI---KQLRKLQAQMKDYQRELEEARASRDEIFAQSKESE 1679
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 40.0 bits (92), Expect = 0.010
Identities = 135/737 (18%), Positives = 279/737 (37%), Gaps = 119/737 (16%)
Query: 168 SDLQKTYQKLGKELENLDYLAFKRQQDLKSPNQRDEIAGARA-SLKENSPLLHSICSACL 226
+ L + QKL + + + QDL+ N++ +A RA +LK+ + L
Sbjct: 740 TSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEM--------L 791
Query: 227 EHSDVASLKASKDTVCEEIQNALNVISNASQGIQNMTTPPEPQA-ATLGSALDELENLIV 285
+ S+V + + + E Q N++ Q IQ + E + L S +++LE+ I
Sbjct: 792 KLSEVRLSQQRESLLAE--QRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEIS 849
Query: 286 -LNPLTVTEEEIRPSLEKRLEAIISGAALLADSSCTRDLHRERII----AECNAIRQALQ 340
L E E R +L + L+ + D+ L+ + ++ E ++Q L
Sbjct: 850 HLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLS 909
Query: 341 DL----LSEYMNNAGKKERSNTLNI-----ALDNMCKKTRDLRRQLRKAIIDHVSDSFLD 391
++ S+ GK + SN ++ L ++ DL+ +L+ + + +
Sbjct: 910 NMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMV 969
Query: 392 TTVPLLV-----LIEAAKNGREKEIKEYAAIFHEHTSRLVEVA--------NLACSMSTN 438
T++ + + E + E +KE A + +L+EV + ++ +
Sbjct: 970 TSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESM 1029
Query: 439 EDGIKIVKIAANHLETLCPQIINAALALAARPKSQAVKNTMEM----------YKRTWEN 488
E + +K + ++ + + A + A + QA ++ E Y+R
Sbjct: 1030 EQQLSELKKTLSSVQNEVQEALQRA-STALSNEQQARRDCQEQAKIAVEAQNKYERELML 1088
Query: 489 H---IHVLTEAVDDITS-------IDDFLAVSESHILE--------------DVNKCIIA 524
H + L A + ++ +++ +ES +LE +V+KC+
Sbjct: 1089 HAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCR 1148
Query: 525 LRDQDADNLDRAAGAIRGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVT 584
D + N R+ H ++ + EGV
Sbjct: 1149 CEDLEKQN-------------RLLHDQIEKLSDKVVASVKEGVQ---------------G 1180
Query: 585 QVNVALEALSKSSLNVLDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEE-H 643
+NV+L KS +L+ +F+ K+I +T R V + + + V LE E
Sbjct: 1181 PLNVSLSEEGKSQEQILEILRFIRREKEIAET----RFEVAQVESLRYRQRVELLERELQ 1236
Query: 644 EVRSHTSIQTEGKTDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIV 703
E++ + + E + ++T A+ E++ ++ V E + D+
Sbjct: 1237 ELQDSLNAERE----KVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQ 1292
Query: 704 LAKNMCMIMMEMTDFTRGKGPLKHTTDVIYA-AKMISESGSRMDVLARQIANQCPDPSCK 762
+ + + +++ L + ++ A K++ E R + + +Q DP +
Sbjct: 1293 MQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTE 1352
Query: 763 QDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIMS--ALDSVTSLIQAAKNLMNAV-V 819
+ Y + + K Q+ EI L E+ S +L + +LIQ+ K +N V
Sbjct: 1353 E----YRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRT 1408
Query: 820 QTVKMSYIASTKIIRIQ 836
+ + KII IQ
Sbjct: 1409 EKETIQKDLDAKIIDIQ 1425
>gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens]
Length = 731
Score = 38.1 bits (87), Expect = 0.037
Identities = 67/348 (19%), Positives = 138/348 (39%), Gaps = 37/348 (10%)
Query: 43 NPSSRKKGRSKRASVLLASVEEATWNLLDKGEKIA------QEATVLKDELTASLEEVRK 96
N K R R L A V++ T + K ++A QEA L T +LE ++
Sbjct: 270 NADHSKSDRMTRG--LRAQVDDLTEAVAAKDSQLAVLKVRLQEADQLLSTRTEALEALQS 327
Query: 97 E---------------SEALKVSAERFTDDPCFLPKREAVVQAARALLAAVTRLLILADM 141
E ++AL+ ER + L + + + ++ AA + +
Sbjct: 328 EKSRIMQDQSEGNSLQNQALQTFQERLHEADATLKREQESYKQMQSEFAARLNKVEM--- 384
Query: 142 IDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKELENLDYLAFKRQQDLKSPNQR 201
+ L + ++ +R + K ++ Q KL E + + +K Q+ + +
Sbjct: 385 -ERQNLAEAITLAERKYSDEKKRVDELQQQVKLYKLNLESSKQELIDYK-QKATRILQSK 442
Query: 202 DEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQNALNVISNASQGIQN 261
+++ SLKE S + S+ ++ L+ K+ EEIQ + I +Q+
Sbjct: 443 EKLIN---SLKEGSGF-EGLDSSTASSMELEELRHEKEMQREEIQKLMGQIHQLRSELQD 498
Query: 262 MTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSLEKRLEAIISGAALLADSSCTR 321
M +A + L +L + I +++E+ LE+ + + D T+
Sbjct: 499 MEAQQVNEAESAREQLQDLHDQIA--GQKASKQELETELERLKQEF---HYIEEDLYRTK 553
Query: 322 DLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLNIALDNMCKK 369
+ + RI I++ L ++ ++N+ + E N L+ + + +K
Sbjct: 554 NTLQSRIKDRDEEIQKLRNQLTNKTLSNSSQSELENRLHQLTETLIQK 601
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 37.4 bits (85), Expect = 0.063
Identities = 152/762 (19%), Positives = 286/762 (37%), Gaps = 122/762 (16%)
Query: 15 DLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLASVEEATWNLLDKGE 74
D++ +++ LE +++ L++ ++ + + K+ L A +EE GE
Sbjct: 1071 DMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEEL-------GE 1123
Query: 75 KIAQE------ATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAARAL 128
+I E A + +L+ LEE+ SE L+ + + KREA Q R
Sbjct: 1124 EIEAERASRAKAEKQRSDLSRELEEI---SERLEEAGGATSAQVELNKKREAEFQKLRRD 1180
Query: 129 LAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVAN-KSDLQKTYQKLGKELENLDYL 187
L T + + + +H + E + N+ K L+K +L E ++L
Sbjct: 1181 LEEAT---LQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSN 1237
Query: 188 A-----FKRQQDLKSPNQRDEIAGARASLKENSPLLHSIC-------------SACLEHS 229
A K + + D+++ + +E L++ + S L+
Sbjct: 1238 AEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEK 1297
Query: 230 D--VASLKASKDTVCEEIQN----------ALNVISNASQGIQNMTTPPEPQAATLGSAL 277
D V+ L SK ++I+ A N +++A Q ++ Q
Sbjct: 1298 DALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGK 1357
Query: 278 DELENLIVLNPLTVTEEEIRPSLE--KRLEAIISGAALLADSSCTRDLHRERIIAECNAI 335
EL+ + V + + + +R E + LA + H E + A+C ++
Sbjct: 1358 AELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASL 1417
Query: 336 RQALQDLLSEYMNNAGKKERSNTLNIALDN-------------------------MCKKT 370
+ Q L +E + ERSN ALD K++
Sbjct: 1418 EKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKES 1477
Query: 371 RDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFHEHTSRLVEVAN 430
R L +L K + +V + LD L + ++EI + E ++ E+
Sbjct: 1478 RSLSTELFK--VKNVYEESLDQ----LETLRRENKNLQQEISDLTEQIAEGGKQIHELEK 1531
Query: 431 LACSMSTNEDGIK-IVKIAANHLETLCPQIINAALALAARPKSQAVKNTME------MYK 483
+ + + I+ ++ A LE +I+ L L + KS+ + E K
Sbjct: 1532 IKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLEL-NQVKSEVDRKIAEKDEEIDQLK 1590
Query: 484 RTWENHIHVLTEAVD-DITSIDDFLAVSESHILEDVNKCIIALRD------QDADNLDRA 536
R + + +D +I S +D L V + + D+N+ I L + N
Sbjct: 1591 RNHTRVVETMQSTLDAEIRSRNDALRVKKK-MEGDLNEMEIQLNHANRLAAESLRNYRNT 1649
Query: 537 AGAIRGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALSKS 596
G ++ + + G+ D E A E R N L + + + T LE +S
Sbjct: 1650 QGILKETQLHLDDALRGQEDLKEQLAIVE---RRANLLQAEIEELWAT-----LEQTERS 1701
Query: 597 SLNVLDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELE-DVSDLEEEHEVRSHTSIQTEG 655
+ + + +D S+++ +H S +I T ++LE DVS L+ E E S E
Sbjct: 1702 --RKIAEQELLDASERV-QLLHTQNTS--LINTKKKLENDVSQLQSEVEEVIQESRNAEE 1756
Query: 656 K-----TDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIE 692
K TD A M + E +K + A +++K L+ ++
Sbjct: 1757 KAKKAITDAAMMAE----ELKKEQDTSAHLERMKKNLEQTVK 1794
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 37.0 bits (84), Expect = 0.082
Identities = 77/369 (20%), Positives = 150/369 (40%), Gaps = 32/369 (8%)
Query: 68 NLLDKGEKIAQEATVLKDELTASLEEVRKE-SEALKVSAERFTDDPCFLPKREAVVQAAR 126
NLL + E+ +E +E+++ L++ E S A ++S E + L K Q R
Sbjct: 936 NLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENE--QRKR 993
Query: 127 ALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKS-DLQKTYQ-KLGKELENL 184
L AA +I+ LLQ VS + +LK+ + K L +T + ++ ++ EN
Sbjct: 994 KLQAA---------LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENK 1044
Query: 185 DYLAFKRQQDLKSPNQRDEIAGARASLKENSPLLH---SICSACLEHSDVASLKASKDTV 241
+Y ++ + S Q EI + ++ L H + +L +
Sbjct: 1045 EY----SEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQT 1100
Query: 242 CEEIQNALNVIS---NASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRP 298
++ N ++++ + +Q I A+ S E +++ P T + E +P
Sbjct: 1101 LQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKP 1160
Query: 299 SLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNT 358
LE+++ A+ L R+ I+ + + L++ L + +K+ N
Sbjct: 1161 ELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQ------QKDDYNR 1214
Query: 359 LNIALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIF 418
L D K+ ++ QLR+ I V +S +D +P E+ + E + A
Sbjct: 1215 LQEQFDEQSKENENIGDQLRQLQI-QVRES-IDGKLPSTDQQESCSSTPGLEEPLFKATE 1272
Query: 419 HEHTSRLVE 427
HT ++E
Sbjct: 1273 QHHTQPVLE 1281
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 36.2 bits (82), Expect = 0.14
Identities = 77/383 (20%), Positives = 148/383 (38%), Gaps = 59/383 (15%)
Query: 83 LKDELTASLEEVRKESEALKVSAER---FTDDPCFLPKREAVV-----QAARALLAAVTR 134
L+ E L ++R++++AL+ E+ F D+ + E V Q L V R
Sbjct: 2040 LEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPR 2099
Query: 135 LLILAD--MIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKELENLDYLAFKRQ 192
+++ +V L H+ ++T + + + +K LQ+ Q+ +E+E L++ + +
Sbjct: 2100 FQPISEHQTREVEQLANHLK--EKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELE 2157
Query: 193 QDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVC---EEIQNAL 249
Q L + A K A E S L+A +D + +EI N
Sbjct: 2158 QAL--------LVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLE 2209
Query: 250 NVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSLEKRLEAIIS 309
+ + ++N E Q + + + E+ L L + + +EK +
Sbjct: 2210 EQLEQFREELENKN--EEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEK-----LG 2262
Query: 310 GAALLADSSCTRDLH-----RERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLNIALD 364
A +D+ T+D H +II E ++ D L+E + ++ + T N ++
Sbjct: 2263 LAIKESDAMSTQDQHVLFGKFAQIIQE----KEVEIDQLNEQVTKLQQQLKITTDNKVIE 2318
Query: 365 NMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFHEHTSR 424
+ RDL Q+ + D E K RE+EI++ + +
Sbjct: 2319 EKNELIRDLETQIECLMSDQ----------------ECVKRNREEEIEQLNEVIEKLQQE 2362
Query: 425 LVEVANL----ACSMSTNEDGIK 443
L + A S+S D +K
Sbjct: 2363 LANIGQKTSMNAHSLSEEADSLK 2385
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 36.2 bits (82), Expect = 0.14
Identities = 58/305 (19%), Positives = 115/305 (37%), Gaps = 53/305 (17%)
Query: 70 LDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPK------------ 117
L + E+ Q + + ++EL S+EE++KE+ LK +E+ + C L
Sbjct: 460 LCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQS 519
Query: 118 ---------------------REAVVQAARALLAAVTRLLILADMIDVMCLLQHVSAFQR 156
+E + Q +L +L + C + +
Sbjct: 520 QNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREH 579
Query: 157 TFESLKNVANKSDLQKTYQKLGKELENLDYLAFKRQQDLKS--PNQRDEIAGARASLKEN 214
E L + +K++ + EL+ +Y K ++ L S ++ +++ S KEN
Sbjct: 580 HIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKEN 639
Query: 215 SPLLHSICSACLEHSDVAS---------LKASKDTVCEEIQNALNVISNASQGI--QNMT 263
+ CL+ + S L+ ++ + EI+N NV+ + S + Q +
Sbjct: 640 LQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLA 699
Query: 264 TPPEPQAATLGSA--LDELENLIVLNPLTVTEEEIRPSLEKRLEAIISGAALLADSSCTR 321
Q A E+EN+ + + E LE +L+ + + ++ C +
Sbjct: 700 YMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVE---DLEHKLQLLSN--EIMDKDRCYQ 754
Query: 322 DLHRE 326
DLH E
Sbjct: 755 DLHAE 759
Score = 30.4 bits (67), Expect = 7.7
Identities = 81/418 (19%), Positives = 159/418 (38%), Gaps = 52/418 (12%)
Query: 8 TLNIDPQDLQVQTFTVEKLLEPLIIQVTT----LVNCPQNPSSRKKGRSKRASVLLASVE 63
TL +D ++L V+ + +L+ ++V T + Q + K +
Sbjct: 667 TLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTS 726
Query: 64 EATWNLLDKGEKIAQEATVLKD------ELTASLEEVR---KESEALKVSAE-------R 107
+ T + D K+ + + D +L A E +R K +A V+ E
Sbjct: 727 QLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLA 786
Query: 108 FTDDPCFLPKREAVVQAARALLAAVTRLLILADMI--DVMCLLQHVSAFQRTFESLKNVA 165
F P ++ ++ + + + AD + L V + + + ES K +
Sbjct: 787 FDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQM- 845
Query: 166 NKSDLQKTYQKL----GKELENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSI 221
SDLQK ++L G+ ENL Q + +QR I+ + + ++
Sbjct: 846 -NSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQR--ISKLQEDTSAHQNVVAET 902
Query: 222 CSACLEHSDVASLKASKDTVCEEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELE 281
SA LE+ + L+ D V E Q + + ++ +++ + + TL E+
Sbjct: 903 LSA-LENKE-KELQLLNDKV-ETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMS 959
Query: 282 NLIVLNPLTVTE--------EEIRPSLEKRLEAIISGAALLAD---------SSCTRDLH 324
++I LN + E +EI SL + +I + A+ S +
Sbjct: 960 SIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYK 1019
Query: 325 RERIIA--ECNAIRQALQDLLSEYMNNAGKKERSNTLNIALDNMCKKTRDLRRQLRKA 380
+E++I C A +DL +Y K + L ++C+ ++ QL++A
Sbjct: 1020 QEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEA 1077
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 35.8 bits (81), Expect = 0.18
Identities = 73/380 (19%), Positives = 146/380 (38%), Gaps = 61/380 (16%)
Query: 83 LKDELTASLEEVRKESEALKVSAER---FTDDPCFLPKREAVV-----QAARALLAAVTR 134
L+ E L ++R++++AL+ E+ F D+ + E V Q L V R
Sbjct: 2040 LEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPR 2099
Query: 135 LLILAD--MIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKELENLDYLAFKRQ 192
+++ +V L H+ ++T + + + +K LQ+ Q+ +E+E L++ + +
Sbjct: 2100 FQPISEHQTREVEQLANHLK--EKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELE 2157
Query: 193 QDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQNALNVI 252
Q L +++ E P L E + + + E+++ +
Sbjct: 2158 QALLVEDRK------HFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREEL 2211
Query: 253 SNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSLEKRLEAIISGAA 312
N ++ +Q + E Q + L ELE + + +EK + A
Sbjct: 2212 ENKNEEVQQLHMQLEIQKKESTTRLQELEQ---------ENKLFKDDMEK-----LGLAI 2257
Query: 313 LLADSSCTRDLH-----RERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLNIALDNMC 367
+D+ T+D H +II E ++ D L+E + ++ + T N ++
Sbjct: 2258 KESDAMSTQDQHVLFGKFAQIIQE----KEVEIDQLNEQVTKLQQQLKITTDNKVIEEKN 2313
Query: 368 KKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFHEHTSRLVE 427
+ RDL Q+ + D E K RE+EI++ + + L
Sbjct: 2314 ELIRDLETQIECLMSDQ----------------ECVKRNREEEIEQLNEVIEKLQQELAN 2357
Query: 428 VANL----ACSMSTNEDGIK 443
+ A S+S D +K
Sbjct: 2358 IGQKTSMNAHSLSEEADSLK 2377
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 35.0 bits (79), Expect = 0.31
Identities = 141/675 (20%), Positives = 260/675 (38%), Gaps = 108/675 (16%)
Query: 87 LTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAARALLAAVTRLLILADMIDVMC 146
+T++ E+ K+ EA + R ++ + EA+V A R A V
Sbjct: 1157 VTSTQIELNKKREAEFLKLRRDLEEATL--QHEAMVAALRKKHAD-----------SVAE 1203
Query: 147 LLQHVSAFQRTFESLKNVANK-----SDLQKTYQKLGKELENLDYLAFKRQQDL-KSPNQ 200
L + + QR + L+ ++ DL + + + K NL+ + + L ++ +
Sbjct: 1204 LGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGK 1263
Query: 201 RDEIAGARASLKENSPLLHSIC---SACLEHSD--VASLKASKDTVC----------EEI 245
+EI + + L L + S LE + V+ L SK EE
Sbjct: 1264 NEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEE 1323
Query: 246 QNALNVISNASQG-------IQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRP 298
A N +++A Q ++ + A L AL + N V T E +
Sbjct: 1324 NKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKA-NSEVAQWRTKYETDAIQ 1382
Query: 299 SLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNT 358
E+ EA A L DS + E + A+C ++ + Q L E + ER+N+
Sbjct: 1383 RTEELEEAKKKLAQRLQDS----EEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANS 1438
Query: 359 LNIALDNMCKKTRDLRRQLR--KAIIDHVS---DSFLDTTVPLLVLIEAAKNGREKEIKE 413
L ALD KK R+ + L K + ++ L + L + KN E+ + +
Sbjct: 1439 LAAALD---KKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQ 1495
Query: 414 YAAIFHEHTSRLVEVANLACSMSTNEDGIKIVKIAANHLE------TLCPQIINAAL--- 464
+ E+ + E+A+L ++ N I ++ + +E L + AAL
Sbjct: 1496 LETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHE 1555
Query: 465 ---ALAARPKSQAVKN-----------TMEMYKRTWENHIHVLTEAVD-DITSIDDFLAV 509
L + + VK+ +E KR ++ + + A+D ++ S ++ + +
Sbjct: 1556 EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRL 1615
Query: 510 SESHILEDVNKCIIALRD------QDADNLDRAAGAIRGRAARVAHIVTGEMDSYEPGAY 563
+ + D+N+ I L + +L G ++ + + G+ D E A
Sbjct: 1616 KKK-MEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAI 1674
Query: 564 TEGVMRNVNFLTSTVIPEFVTQVNVALEALSKSSLNVLDDNQFVDISKKIYDTIHDIRCS 623
E R N L + V E + A + +LD N+ V + +H S
Sbjct: 1675 VE---RRANLLQAEV-EELRATLEQTERARKLAEQELLDSNERVQL-------LHTQNTS 1723
Query: 624 VMMIRTPEELE-DVSDLEEEHEVRSHTSIQTEGK-----TDRAKMTQLPEAEKEKIAEQV 677
+I T ++LE D+ L+ E E S + E K TD A M + E +K +
Sbjct: 1724 --LIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAE----ELKKEQDTS 1777
Query: 678 ADFKKVKSKLDAEIE 692
A +++K L+ ++
Sbjct: 1778 AHLERMKKNLEQTVK 1792
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 34.7 bits (78), Expect = 0.41
Identities = 61/243 (25%), Positives = 112/243 (46%), Gaps = 52/243 (21%)
Query: 672 KIAEQVADFKKVKSKLDAE-----IEIWDDTSN-DIIVLAK----NMCMIMMEMTDFTRG 721
++ EQ+ + ++VK KL+ E +E+ D TSN + I+ AK MC + + + R
Sbjct: 1202 ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRS 1261
Query: 722 KG--PLKHTTDVI-YAAKMISESGSRMDVLARQIANQCPDPSCKQDLLAYLEQIKF-YSH 777
K + D+ AK+ +E+G L+RQ+ K+ L++ L + K Y+
Sbjct: 1262 KAEETQRSVNDLTSQRAKLQTENGE----LSRQLDE-------KEALISQLTRGKLTYTQ 1310
Query: 778 QLK-ICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQ 836
QL+ + Q++ E++ A +++ +Q+A++ + + + + A ++ R+
Sbjct: 1311 QLEDLKRQLEEEVK---------AKNALAHALQSARHDCDLLREQYEEETEAKAELQRVL 1361
Query: 837 SPAGPRHPVVMWRMK------------APAKKPLIKR-EKPEETCAAV--RRGSAKKKIH 881
S A V WR K AKK L +R ++ EE AV + S +K H
Sbjct: 1362 SKANSE--VAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKH 1419
Query: 882 PLQ 884
LQ
Sbjct: 1420 RLQ 1422
>gi|5031999 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
Length = 359
Score = 34.3 bits (77), Expect = 0.53
Identities = 26/133 (19%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Query: 203 EIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQNALNVISNASQGIQNM 262
E++ +R+ + + ++ S+ +H+ V K + V E +N L + +A + + +
Sbjct: 41 ELSLSRSLVNSSDKIIRKAGSSIFQHN-VEGWKINSSLVLEIRKNILRFL-DAERDVSVV 98
Query: 263 TTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSLEKRLE--AIISGAALLADSSCT 320
+ +P + LD L + + L E+ P +R + A++ + +L DS C
Sbjct: 99 KSSFKP-GDVIHYVLDRRRTLNISHDLHSLLPEVSPMKNRRFKTCAVVGNSGILLDSECG 157
Query: 321 RDLHRERIIAECN 333
+++ + CN
Sbjct: 158 KEIDSHNFVIRCN 170
>gi|110611218 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 33.9 bits (76), Expect = 0.69
Identities = 71/303 (23%), Positives = 108/303 (35%), Gaps = 45/303 (14%)
Query: 6 PITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLASVEEA 65
P L P + + KL E Q T C Q S +LA E
Sbjct: 661 PTLLKHPPAPAEPSSDLASKLREAEETQSTLQAECDQYRS------------ILAETEGM 708
Query: 66 TWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAA 125
L D + + +E V + ++ A+ EE++K +K E L + V +
Sbjct: 709 ---LRDLQKSVEEEEQVWRAKVGAAEEELQKSRVTVKHLEEIVEKLKGELESSDQVREHT 765
Query: 126 RALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNV-ANKSDLQKTYQKLGKELENL 184
L A + + + A + Q ES + A KS+ QK
Sbjct: 766 SHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEAQK----------QS 815
Query: 185 DYLAFKRQQ--DLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVC 242
D LA RQQ ++KS + +IAGA AS E P D LK
Sbjct: 816 DELALVRQQLSEMKSHVEDGDIAGAPASSPEAPPA----------EQDPVQLKT------ 859
Query: 243 EEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSLEK 302
+++ ++ + Q +T E + +ELE L PL +E E L++
Sbjct: 860 -QLEWTEAILEDEQTQRQKLTAEFEEAQTSACRLQEELEKLRTAGPLESSETEEASQLKE 918
Query: 303 RLE 305
RLE
Sbjct: 919 RLE 921
>gi|110611220 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 33.9 bits (76), Expect = 0.69
Identities = 71/303 (23%), Positives = 108/303 (35%), Gaps = 45/303 (14%)
Query: 6 PITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLASVEEA 65
P L P + + KL E Q T C Q S +LA E
Sbjct: 661 PTLLKHPPAPAEPSSDLASKLREAEETQSTLQAECDQYRS------------ILAETEGM 708
Query: 66 TWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAA 125
L D + + +E V + ++ A+ EE++K +K E L + V +
Sbjct: 709 ---LRDLQKSVEEEEQVWRAKVGAAEEELQKSRVTVKHLEEIVEKLKGELESSDQVREHT 765
Query: 126 RALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNV-ANKSDLQKTYQKLGKELENL 184
L A + + + A + Q ES + A KS+ QK
Sbjct: 766 SHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEAQK----------QS 815
Query: 185 DYLAFKRQQ--DLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVC 242
D LA RQQ ++KS + +IAGA AS E P D LK
Sbjct: 816 DELALVRQQLSEMKSHVEDGDIAGAPASSPEAPPA----------EQDPVQLKT------ 859
Query: 243 EEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSLEK 302
+++ ++ + Q +T E + +ELE L PL +E E L++
Sbjct: 860 -QLEWTEAILEDEQTQRQKLTAEFEEAQTSACRLQEELEKLRTAGPLESSETEEASQLKE 918
Query: 303 RLE 305
RLE
Sbjct: 919 RLE 921
>gi|39725952 angiogenic factor VG5Q [Homo sapiens]
Length = 714
Score = 33.5 bits (75), Expect = 0.91
Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 7/102 (6%)
Query: 240 TVCEEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPS 299
T C E +N N+ A GI + +PP+ T G+ ++ + + N + +E+I +
Sbjct: 305 TSCNEEENFANMKKKAKIGIHHKNSPPKVTVPTSGNTIESPLHENISNSTSFKDEKIMET 364
Query: 300 LEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQD 341
+ E I+ S T D + E I +E N + +D
Sbjct: 365 DSEPEEGEIT-------DSQTEDSYDEAITSEGNVTAEDSED 399
>gi|33946313 ninein isoform 4 [Homo sapiens]
Length = 2096
Score = 33.5 bits (75), Expect = 0.91
Identities = 77/370 (20%), Positives = 143/370 (38%), Gaps = 37/370 (10%)
Query: 15 DLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRA-----SVLLASVEEATWNL 69
+L+++ +++L L +VT LV S +K +A + + +++ L
Sbjct: 1459 ELELEKTKLQELTRKLKERVTILVKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELL 1518
Query: 70 LDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAARALL 129
+ EK+ QE ++L++E+T EE LK+ + + + K E V Q A+
Sbjct: 1519 RYESEKLQQENSILRNEITTLNEE--DSISNLKLGTLNGSQEEMW-QKTETVKQENAAVQ 1575
Query: 130 AAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKL-----GKELENL 184
V L I + + + T S KN N+ LQ+ Q+L KE E
Sbjct: 1576 KMVEN---LKKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPG 1632
Query: 185 DYLAFKRQQD---LKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTV 241
+ +R+Q+ LK +R ++ + + L + + LK + +
Sbjct: 1633 NSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKM 1692
Query: 242 -----CEEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTE--- 293
C ++ + IS+ + + E + L S +D+L +L T
Sbjct: 1693 KQLHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEELNSCVDKLAKSSLLEHRIATMKQE 1752
Query: 294 ----EEIRPSLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMN- 348
E SL+ +L A L D+ +L R+ ++ +Q + L E M+
Sbjct: 1753 QKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVMSL 1812
Query: 349 -----NAGKK 353
NAG K
Sbjct: 1813 HKQLQNAGGK 1822
>gi|33946321 ninein isoform 5 [Homo sapiens]
Length = 2090
Score = 33.5 bits (75), Expect = 0.91
Identities = 77/370 (20%), Positives = 143/370 (38%), Gaps = 37/370 (10%)
Query: 15 DLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRA-----SVLLASVEEATWNL 69
+L+++ +++L L +VT LV S +K +A + + +++ L
Sbjct: 1453 ELELEKTKLQELTRKLKERVTILVKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELL 1512
Query: 70 LDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAARALL 129
+ EK+ QE ++L++E+T EE LK+ + + + K E V Q A+
Sbjct: 1513 RYESEKLQQENSILRNEITTLNEE--DSISNLKLGTLNGSQEEMW-QKTETVKQENAAVQ 1569
Query: 130 AAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKL-----GKELENL 184
V L I + + + T S KN N+ LQ+ Q+L KE E
Sbjct: 1570 KMVEN---LKKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPG 1626
Query: 185 DYLAFKRQQD---LKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTV 241
+ +R+Q+ LK +R ++ + + L + + LK + +
Sbjct: 1627 NSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKM 1686
Query: 242 -----CEEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTE--- 293
C ++ + IS+ + + E + L S +D+L +L T
Sbjct: 1687 KQLHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEELNSCVDKLAKSSLLEHRIATMKQE 1746
Query: 294 ----EEIRPSLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMN- 348
E SL+ +L A L D+ +L R+ ++ +Q + L E M+
Sbjct: 1747 QKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVMSL 1806
Query: 349 -----NAGKK 353
NAG K
Sbjct: 1807 HKQLQNAGGK 1816
>gi|148536871 ninein isoform 1 [Homo sapiens]
Length = 2046
Score = 33.5 bits (75), Expect = 0.91
Identities = 77/370 (20%), Positives = 143/370 (38%), Gaps = 37/370 (10%)
Query: 15 DLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRA-----SVLLASVEEATWNL 69
+L+++ +++L L +VT LV S +K +A + + +++ L
Sbjct: 1453 ELELEKTKLQELTRKLKERVTILVKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELL 1512
Query: 70 LDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAARALL 129
+ EK+ QE ++L++E+T EE LK+ + + + K E V Q A+
Sbjct: 1513 RYESEKLQQENSILRNEITTLNEE--DSISNLKLGTLNGSQEEMW-QKTETVKQENAAVQ 1569
Query: 130 AAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKL-----GKELENL 184
V L I + + + T S KN N+ LQ+ Q+L KE E
Sbjct: 1570 KMVEN---LKKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPG 1626
Query: 185 DYLAFKRQQD---LKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTV 241
+ +R+Q+ LK +R ++ + + L + + LK + +
Sbjct: 1627 NSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKM 1686
Query: 242 -----CEEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTE--- 293
C ++ + IS+ + + E + L S +D+L +L T
Sbjct: 1687 KQLHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEELNSCVDKLAKSSLLEHRIATMKQE 1746
Query: 294 ----EEIRPSLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMN- 348
E SL+ +L A L D+ +L R+ ++ +Q + L E M+
Sbjct: 1747 QKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVMSL 1806
Query: 349 -----NAGKK 353
NAG K
Sbjct: 1807 HKQLQNAGGK 1816
>gi|148536869 ninein isoform 2 [Homo sapiens]
Length = 2133
Score = 33.5 bits (75), Expect = 0.91
Identities = 77/370 (20%), Positives = 143/370 (38%), Gaps = 37/370 (10%)
Query: 15 DLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRA-----SVLLASVEEATWNL 69
+L+++ +++L L +VT LV S +K +A + + +++ L
Sbjct: 1453 ELELEKTKLQELTRKLKERVTILVKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELL 1512
Query: 70 LDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAARALL 129
+ EK+ QE ++L++E+T EE LK+ + + + K E V Q A+
Sbjct: 1513 RYESEKLQQENSILRNEITTLNEE--DSISNLKLGTLNGSQEEMW-QKTETVKQENAAVQ 1569
Query: 130 AAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKL-----GKELENL 184
V L I + + + T S KN N+ LQ+ Q+L KE E
Sbjct: 1570 KMVEN---LKKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPG 1626
Query: 185 DYLAFKRQQD---LKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTV 241
+ +R+Q+ LK +R ++ + + L + + LK + +
Sbjct: 1627 NSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKM 1686
Query: 242 -----CEEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTE--- 293
C ++ + IS+ + + E + L S +D+L +L T
Sbjct: 1687 KQLHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEELNSCVDKLAKSSLLEHRIATMKQE 1746
Query: 294 ----EEIRPSLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMN- 348
E SL+ +L A L D+ +L R+ ++ +Q + L E M+
Sbjct: 1747 QKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVMSL 1806
Query: 349 -----NAGKK 353
NAG K
Sbjct: 1807 HKQLQNAGGK 1816
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.129 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,772,896
Number of Sequences: 37866
Number of extensions: 1214915
Number of successful extensions: 5366
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 90
Number of HSP's that attempted gapping in prelim test: 5221
Number of HSP's gapped (non-prelim): 265
length of query: 895
length of database: 18,247,518
effective HSP length: 111
effective length of query: 784
effective length of database: 14,044,392
effective search space: 11010803328
effective search space used: 11010803328
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.