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Search of human proteins with 188497683
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188497683 FAST kinase domains 1 [Homo sapiens]
(847 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188497683 FAST kinase domains 1 [Homo sapiens] 1684 0.0
gi|169167993 PREDICTED: hypothetical protein [Homo sapiens] 407 e-113
gi|169167430 PREDICTED: hypothetical protein [Homo sapiens] 407 e-113
gi|40068497 FAST kinase domains 3 [Homo sapiens] 97 8e-20
gi|11141903 FAST kinase domains 5 [Homo sapiens] 70 8e-12
gi|40217812 cell cycle progression 2 protein isoform 1 [Homo sap... 69 1e-11
gi|40217810 cell cycle progression 2 protein isoform 2 [Homo sap... 69 2e-11
gi|13569848 cell cycle progression 2 protein isoform 2 [Homo sap... 69 2e-11
gi|209969832 FAST kinase domains 2 [Homo sapiens] 57 6e-08
gi|209969830 FAST kinase domains 2 [Homo sapiens] 57 6e-08
gi|45267832 FAST kinase domains 2 [Homo sapiens] 57 6e-08
gi|5729822 Fas-activated serine/threonine kinase isoform 1 [Homo... 42 0.003
gi|39995107 Fas-activated serine/threonine kinase isoform 4 [Hom... 42 0.003
gi|126032350 protein kinase, DNA-activated, catalytic polypeptid... 35 0.22
gi|13654237 protein kinase, DNA-activated, catalytic polypeptide... 35 0.22
gi|113430845 PREDICTED: similar to protein kinase, DNA-activated... 35 0.29
gi|112293287 tudor domain containing 7 [Homo sapiens] 33 0.85
gi|12597641 leucine rich repeat containing 19 [Homo sapiens] 33 1.5
gi|157694513 leucine-rich repeat-containing G protein-coupled re... 32 1.9
gi|148277106 hypothetical protein LOC442213 [Homo sapiens] 31 4.2
gi|71143104 potassium channel tetramerisation domain containing ... 31 4.2
gi|7662320 leucine-rich repeats and immunoglobulin-like domains ... 31 5.5
gi|239754394 PREDICTED: hypothetical protein XP_002345990 [Homo ... 30 7.2
gi|239748968 PREDICTED: hypothetical protein XP_002346842 [Homo ... 30 7.2
gi|239742990 PREDICTED: hypothetical protein XP_002342728 [Homo ... 30 7.2
>gi|188497683 FAST kinase domains 1 [Homo sapiens]
Length = 847
Score = 1684 bits (4362), Expect = 0.0
Identities = 847/847 (100%), Positives = 847/847 (100%)
Query: 1 MKKTPVFLESLVTNMLRLRAICPFSWRVFQFRPISCEPLIIQMNKCTDEEQMFGFIERNK 60
MKKTPVFLESLVTNMLRLRAICPFSWRVFQFRPISCEPLIIQMNKCTDEEQMFGFIERNK
Sbjct: 1 MKKTPVFLESLVTNMLRLRAICPFSWRVFQFRPISCEPLIIQMNKCTDEEQMFGFIERNK 60
Query: 61 AILSEKQVGCAFDMLWKLQKQKTSLLKNAEYVRDHPQFLTLHNLATNKFKLMNDDTLVNV 120
AILSEKQVGCAFDMLWKLQKQKTSLLKNAEYVRDHPQFLTLHNLATNKFKLMNDDTLVNV
Sbjct: 61 AILSEKQVGCAFDMLWKLQKQKTSLLKNAEYVRDHPQFLTLHNLATNKFKLMNDDTLVNV 120
Query: 121 LYVTQQFAGEAHDPLVEALVTEAWRRLERFDIKLLSEFSSCLADQHLYFSPLMGKIADIV 180
LYVTQQFAGEAHDPLVEALVTEAWRRLERFDIKLLSEFSSCLADQHLYFSPLMGKIADIV
Sbjct: 121 LYVTQQFAGEAHDPLVEALVTEAWRRLERFDIKLLSEFSSCLADQHLYFSPLMGKIADIV 180
Query: 181 HRNLETTQDLSSLSVLMVNISSLISRHFQQQLVNKTELLFDTIDSSEVNVAKSIAKFLRN 240
HRNLETTQDLSSLSVLMVNISSLISRHFQQQLVNKTELLFDTIDSSEVNVAKSIAKFLRN
Sbjct: 181 HRNLETTQDLSSLSVLMVNISSLISRHFQQQLVNKTELLFDTIDSSEVNVAKSIAKFLRN 240
Query: 241 VRYRYQPLLERCNNVFLSNVDHLDLDSISKILSVYKFLQFNSFEFIIMAKKKLTEMIPLC 300
VRYRYQPLLERCNNVFLSNVDHLDLDSISKILSVYKFLQFNSFEFIIMAKKKLTEMIPLC
Sbjct: 241 VRYRYQPLLERCNNVFLSNVDHLDLDSISKILSVYKFLQFNSFEFIIMAKKKLTEMIPLC 300
Query: 301 NHPASFVKLFVALGPIAGPEEKKQLKSTMLLMSEDLTGEQALAVLGAMGDMESRNSCLIK 360
NHPASFVKLFVALGPIAGPEEKKQLKSTMLLMSEDLTGEQALAVLGAMGDMESRNSCLIK
Sbjct: 301 NHPASFVKLFVALGPIAGPEEKKQLKSTMLLMSEDLTGEQALAVLGAMGDMESRNSCLIK 360
Query: 361 RVTSVLHKHLDGYKPLELLKITQELTFLHFQRKEFFAKLRELLLSYLKNSFIPTEVSVLV 420
RVTSVLHKHLDGYKPLELLKITQELTFLHFQRKEFFAKLRELLLSYLKNSFIPTEVSVLV
Sbjct: 361 RVTSVLHKHLDGYKPLELLKITQELTFLHFQRKEFFAKLRELLLSYLKNSFIPTEVSVLV 420
Query: 421 RAISLLPSPHLDEVGISRIEAVLPQCDLNNLSSFATSVLRWIQHDHMYLDNMTAKQLKLL 480
RAISLLPSPHLDEVGISRIEAVLPQCDLNNLSSFATSVLRWIQHDHMYLDNMTAKQLKLL
Sbjct: 421 RAISLLPSPHLDEVGISRIEAVLPQCDLNNLSSFATSVLRWIQHDHMYLDNMTAKQLKLL 480
Query: 481 QKLDHYGRQRLQHSNSLDLLRKELKSLKGNTFPESLLEEMIATLQHFMDDINYINVGEIA 540
QKLDHYGRQRLQHSNSLDLLRKELKSLKGNTFPESLLEEMIATLQHFMDDINYINVGEIA
Sbjct: 481 QKLDHYGRQRLQHSNSLDLLRKELKSLKGNTFPESLLEEMIATLQHFMDDINYINVGEIA 540
Query: 541 SFISSTDYLSTLLLDRIASVAVQQIEKIHPFTIPAIIRPFSVLNYDPPQRDEFLGTCVQH 600
SFISSTDYLSTLLLDRIASVAVQQIEKIHPFTIPAIIRPFSVLNYDPPQRDEFLGTCVQH
Sbjct: 541 SFISSTDYLSTLLLDRIASVAVQQIEKIHPFTIPAIIRPFSVLNYDPPQRDEFLGTCVQH 600
Query: 601 LNSYLGILDPFILVFLGFSLATLEYFPEDLLKAIFNIKFLARLDSQLEILSPSRSARVQF 660
LNSYLGILDPFILVFLGFSLATLEYFPEDLLKAIFNIKFLARLDSQLEILSPSRSARVQF
Sbjct: 601 LNSYLGILDPFILVFLGFSLATLEYFPEDLLKAIFNIKFLARLDSQLEILSPSRSARVQF 660
Query: 661 HLMELNRSVCLECPEFQIPWFHDRFCQQYNKGIGGMDGTQQQIFKMLAEVLGGINCVKAS 720
HLMELNRSVCLECPEFQIPWFHDRFCQQYNKGIGGMDGTQQQIFKMLAEVLGGINCVKAS
Sbjct: 661 HLMELNRSVCLECPEFQIPWFHDRFCQQYNKGIGGMDGTQQQIFKMLAEVLGGINCVKAS 720
Query: 721 VLTPYYHKVDFECILDKRKKPLPYGSHNIALGQLPEMPWESNIEIVGSRLPPGAERIALE 780
VLTPYYHKVDFECILDKRKKPLPYGSHNIALGQLPEMPWESNIEIVGSRLPPGAERIALE
Sbjct: 721 VLTPYYHKVDFECILDKRKKPLPYGSHNIALGQLPEMPWESNIEIVGSRLPPGAERIALE 780
Query: 781 FLDSKALCRNIPHMKGKSAMKKRHLEILGYRVIQISQFEWNSMALSTKDARMDYLRECIF 840
FLDSKALCRNIPHMKGKSAMKKRHLEILGYRVIQISQFEWNSMALSTKDARMDYLRECIF
Sbjct: 781 FLDSKALCRNIPHMKGKSAMKKRHLEILGYRVIQISQFEWNSMALSTKDARMDYLRECIF 840
Query: 841 GEVKSCL 847
GEVKSCL
Sbjct: 841 GEVKSCL 847
>gi|169167993 PREDICTED: hypothetical protein [Homo sapiens]
Length = 302
Score = 407 bits (1045), Expect = e-113
Identities = 226/338 (66%), Positives = 241/338 (71%), Gaps = 77/338 (22%)
Query: 2 KKTPVFLESLVTNMLRLRAICPFSWRVFQFRPISCEPLIIQMNKCTDEEQMFGFIERNKA 61
+KT V L+SLVTNMLRLRAICPFSW VFQFR ISCEPLIIQMNKC DEEQ+F FIERNK
Sbjct: 42 QKTSVCLDSLVTNMLRLRAICPFSWTVFQFRLISCEPLIIQMNKCIDEEQIFDFIERNKI 101
Query: 62 ILSEKQVGCAFDMLWKLQKQKTSLLKNAEYVRDHPQFLTLHNLATNKFKLMNDDTLVNVL 121
ILSEKQVGC F++LWKLQKQK SLLKN EYVRDH QFLTLHNLATNKFKLMN +TLVNVL
Sbjct: 102 ILSEKQVGCTFNILWKLQKQKISLLKNVEYVRDHSQFLTLHNLATNKFKLMNGNTLVNVL 161
Query: 122 YVTQQFAGEAHDPLVEALVTEAWRRLERFDIKLLSEFSSCLADQHLYFSPLMGKIADIVH 181
Y+TQQ FDIKLLSEFSSCLADQHLYFSPLMGKIADIVH
Sbjct: 162 YITQQ-----------------------FDIKLLSEFSSCLADQHLYFSPLMGKIADIVH 198
Query: 182 RNLETTQDLSSLSVLMVNISSLISRHFQQQLVNKTELLFDTIDSSEVNVAKSIAKFLRNV 241
RNLET Q+LSSLSVLMVNISSLISRHFQ+QLVNKTEL+FDT DSSEVNVAK + +FLRN
Sbjct: 199 RNLETIQNLSSLSVLMVNISSLISRHFQEQLVNKTELVFDTTDSSEVNVAKRMVQFLRNF 258
Query: 242 RYRYQPLLERCNNVFLSNVDHLDLDSISKILSVYKFLQFNSFEFIIMAKKKLTEMIPLCN 301
RY YQPLLE F++F
Sbjct: 259 RYHYQPLLE-------------------------SFVKF--------------------- 272
Query: 302 HPASFVKLFVALGPIAGPEEKKQLKSTMLLMSEDLTGE 339
FVALGPIAGPEEKKQLKSTMLLMSE+LT E
Sbjct: 273 --------FVALGPIAGPEEKKQLKSTMLLMSEELTNE 302
>gi|169167430 PREDICTED: hypothetical protein [Homo sapiens]
Length = 302
Score = 407 bits (1045), Expect = e-113
Identities = 226/338 (66%), Positives = 241/338 (71%), Gaps = 77/338 (22%)
Query: 2 KKTPVFLESLVTNMLRLRAICPFSWRVFQFRPISCEPLIIQMNKCTDEEQMFGFIERNKA 61
+KT V L+SLVTNMLRLRAICPFSW VFQFR ISCEPLIIQMNKC DEEQ+F FIERNK
Sbjct: 42 QKTSVCLDSLVTNMLRLRAICPFSWTVFQFRLISCEPLIIQMNKCIDEEQIFDFIERNKI 101
Query: 62 ILSEKQVGCAFDMLWKLQKQKTSLLKNAEYVRDHPQFLTLHNLATNKFKLMNDDTLVNVL 121
ILSEKQVGC F++LWKLQKQK SLLKN EYVRDH QFLTLHNLATNKFKLMN +TLVNVL
Sbjct: 102 ILSEKQVGCTFNILWKLQKQKISLLKNVEYVRDHSQFLTLHNLATNKFKLMNGNTLVNVL 161
Query: 122 YVTQQFAGEAHDPLVEALVTEAWRRLERFDIKLLSEFSSCLADQHLYFSPLMGKIADIVH 181
Y+TQQ FDIKLLSEFSSCLADQHLYFSPLMGKIADIVH
Sbjct: 162 YITQQ-----------------------FDIKLLSEFSSCLADQHLYFSPLMGKIADIVH 198
Query: 182 RNLETTQDLSSLSVLMVNISSLISRHFQQQLVNKTELLFDTIDSSEVNVAKSIAKFLRNV 241
RNLET Q+LSSLSVLMVNISSLISRHFQ+QLVNKTEL+FDT DSSEVNVAK + +FLRN
Sbjct: 199 RNLETIQNLSSLSVLMVNISSLISRHFQEQLVNKTELVFDTTDSSEVNVAKRMVQFLRNF 258
Query: 242 RYRYQPLLERCNNVFLSNVDHLDLDSISKILSVYKFLQFNSFEFIIMAKKKLTEMIPLCN 301
RY YQPLLE F++F
Sbjct: 259 RYHYQPLLE-------------------------SFVKF--------------------- 272
Query: 302 HPASFVKLFVALGPIAGPEEKKQLKSTMLLMSEDLTGE 339
FVALGPIAGPEEKKQLKSTMLLMSE+LT E
Sbjct: 273 --------FVALGPIAGPEEKKQLKSTMLLMSEELTNE 302
>gi|40068497 FAST kinase domains 3 [Homo sapiens]
Length = 662
Score = 96.7 bits (239), Expect = 8e-20
Identities = 133/518 (25%), Positives = 213/518 (41%), Gaps = 98/518 (18%)
Query: 349 GDMESRNSCLIKRVTSVLHKHLDGYKPLELLKITQELTFLHFQRKEFFAKLRELLLSYLK 408
G ME RN C++ S++ H G LEL+ + L ++ E
Sbjct: 211 GGMEVRNLCILGE--SLITLHSSGCVTLELI-----INQLQGEKLE-------------- 249
Query: 409 NSFIPTEVSVLVRAISLLPSPHLDEVGISRIEAVLPQCDLNNLSSFATSVLRWIQHDHMY 468
+F P ++ L R + + +DE Q LN +++F+ S++ + +
Sbjct: 250 -TFTPEDIVALYRILQAC-TEKVDE----------HQTFLNKINNFSLSIVSNLS-PKLI 296
Query: 469 LDNMTA-------KQLKLLQKLDHYGRQRLQHSNSLDLLRKELKSL----KGNTFPESLL 517
+TA + L+ KL Y + + H + +L R+ L++ +TF L
Sbjct: 297 SQMLTALVVLDQSQAFPLIIKLGKYVVRHVPHFTNEEL-RRVLEAFIYFGHHDTFFTKAL 355
Query: 518 EEMIATLQHFMDDINYINVGEIASFISSTDYLSTLLLDRIASVAVQQIEKIHPFTIPAII 577
E +A + +D V E + S LS +L+ +A V Q EK P I A++
Sbjct: 356 EHRVAAVCLTLDPEVVCRVME---YCSRELILSKPILNAVAETFVCQTEKFSPRQISALM 412
Query: 578 RPFSVLNYDPPQRDEFLGTCVQHLNSYLGILDPFILVFLGFSLATLEYFPEDLLKAIFNI 637
PF LNY PP L ++ P L+ L S + E P + L IF
Sbjct: 413 EPFGKLNYLPPNASALFRKLENVLFTHFNYFPPKSLLKLLHSCSLNECHPVNFLAKIFKP 472
Query: 638 KFLARL---DSQLEILSPSRSARVQFHLMELNRSVCLECP---------EFQIPWFHDRF 685
FL RL +S L+ LS ++ L +L + LECP ++Q+ F
Sbjct: 473 LFLQRLQGKESHLDTLSRAQ-------LTQLFLASVLECPFYKGPKLLPKYQVKSFLTPC 525
Query: 686 CQQYNKGIGGMDGTQQQIFKM-LAEVLGGINCVKASVLTPYYHKVDFECILDKRKKPLPY 744
C +D + K+ L +LG VLTPY + +D E LD+ LP
Sbjct: 526 CSLETP----VDSQLYRYVKIGLTNLLGARLYFAPKVLTPYCYTIDVEIKLDEEGFVLPS 581
Query: 745 GSHNIALGQLPEMPWESNIEIVGSRLPPGAERIALEFLDSKALCRNIPHMKGKSAMKKRH 804
+N +I +RIAL K C N H+ GK A+K+RH
Sbjct: 582 ---------------TANEDI--------HKRIALCIDGPKRFCSNSKHLLGKEAIKQRH 618
Query: 805 LEILGYRVIQISQFEWNSMALSTKDARMDYLRECIFGE 842
L++LGY+V+QI E L ++ ++YL+ +F +
Sbjct: 619 LQLLGYQVVQIPYHEIG--MLKSRRELVEYLQRKLFSQ 654
>gi|11141903 FAST kinase domains 5 [Homo sapiens]
Length = 764
Score = 70.1 bits (170), Expect = 8e-12
Identities = 89/403 (22%), Positives = 159/403 (39%), Gaps = 100/403 (24%)
Query: 528 MDDINYIN-VGEIAS----------------FISSTDYLSTLLLDRIASVAVQQIEKIHP 570
+D IN++ +GEIA + S+ +L+ +++ +A+ ++
Sbjct: 368 VDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAVAASLPPRVAHCRS 427
Query: 571 FTIPAIIRPFSVLNYDPPQRDEFLGTCVQHLNSYLGILD--PFILVFLGFSLATLEYFPE 628
+ I+ F LNY PP +EF + + ++ + + P L LA LEYFP
Sbjct: 428 KDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQYPEHLPTCLLGLAFLEYFPV 487
Query: 629 DLLKAIFNIKF--LARLDSQLEILSPSRSARVQFHLMELNRSVCLECPEFQIPWFHDRFC 686
+L+ + F LA+ ++ ++L L L+ +V +ECP+++
Sbjct: 488 ELIDFALSPGFVRLAQERTKFDLLK---------ELYTLDGTVGIECPDYRGNRLSTHLQ 538
Query: 687 QQYN--------KGIGGMDGTQQQIFKMLAEVLGGINCVKASVLTPYYHKVDFECILDKR 738
Q+ + K + + +F +L +LGG VK ++ P+ D E LD
Sbjct: 539 QEGSELLWYLAEKDMNSKPEFLETVF-LLETMLGGPQYVKHHMILPHTRSSDLEVQLDVN 597
Query: 739 KKPLPYG-----SHNIALGQLPEMPWESNIEIVGSRL--------------PPGAERIAL 779
KPLP+ + N+A +L + +++ L PG + + L
Sbjct: 598 LKPLPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKARGHFQGKTESEPGQQPMEL 657
Query: 780 E---------FLDS--------------KALCRNIPHMK-------------------GK 797
E FL + A C P MK G
Sbjct: 658 ENKAAVPLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTNRNQYCYGSRDLLGL 717
Query: 798 SAMKKRHLEILGYRVIQISQFEWNSMALSTKDARMDYLRECIF 840
MK+R L LGYRV+++S +EW + T+ ++ +L E +F
Sbjct: 718 HNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKVF 760
Score = 33.9 bits (76), Expect = 0.65
Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 35/166 (21%)
Query: 139 LVTEAWRRLERFDIKLLSEFSSCLADQHLYFSPLMGKIADIVH------RNLETTQDLSS 192
LV + WR L R + L+ FSS L +L++ L ++ +VH N + +QDL
Sbjct: 246 LVADLWRYLGRKVPRFLNIFSSYL---NLHWKDL--SLSQLVHLIYVIGENRQVSQDL-- 298
Query: 193 LSVLMVNISSLISRHFQQQLVNKTELLFDTIDSSEVNVAKSIAKFLRNVRYRYQPLLERC 252
M + SLI ++ L+N E+ TI + ++++F+ + +
Sbjct: 299 ----MQKLESLILKYID--LINLEEV--GTICLGFFKSSTNLSEFV----------MRKI 340
Query: 253 NNVFLSNVDHLDLDSISKILSVYKFLQFNSFEFIIMAKKKLTEMIP 298
++ +N+ HL S+ I+ +++F + F+ K++ E+ P
Sbjct: 341 GDLACANIQHLSSRSLVNIVKMFRFTHVDHINFM----KQIGEIAP 382
>gi|40217812 cell cycle progression 2 protein isoform 1 [Homo
sapiens]
Length = 631
Score = 69.3 bits (168), Expect = 1e-11
Identities = 112/521 (21%), Positives = 225/521 (43%), Gaps = 62/521 (11%)
Query: 332 MSEDLTGEQALAVLGAMGDMESRNSCLIKRVTSVLHKHLDGYKPLELLKITQELTFLHFQ 391
+S+ L AL + A +++S + R+ + +KHL + ++QE
Sbjct: 146 LSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLKYKHL-AFLAESCATLSQEQ-----H 199
Query: 392 RKEFFAKLRELLLSYLKNSFIPTEVSVLVRAISLLPSPHLDEVGISRIEAVLPQCDLNNL 451
+E A+L L++L+ + E S + + ++ HL E ++R+E +C L +
Sbjct: 200 SQELLAEL----LTHLERRWTEIEDSHTLVTV-MMKVGHLSEPLMNRLE---DKC-LELV 250
Query: 452 SSFATSVLRWIQHDHMYLDNMTAKQLKLLQKLDHYGRQRLQHSNSLDLLRKELKSLKGNT 511
F + LR + + L + + + LL+ + ++ Q+ S + D+L + +
Sbjct: 251 EHFGPNELRKVL---VMLAAQSRRSVPLLRAISYHLVQK-PFSLTKDVLLDVAYAYGKLS 306
Query: 512 FPESLLEEMIATLQHFMDDINYINVGEIASFISSTDYLSTLLLDRIASVAVQQIEKIHPF 571
F ++ + + +AT + + + GE+A S L L L + A + +
Sbjct: 307 FHQTQVSQRLAT--DLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNRAQDI 364
Query: 572 TIP---AIIRPFSVLNYDPPQRDEFLGTCVQHLNSYLGILDPFILVFLGFSLATLEYFPE 628
T+P +++ F+ LN+ P Q D+F + L S L L+P + V L ++L L+ E
Sbjct: 365 TLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQQARE 424
Query: 629 DLLKAI----FNIKFLARLDSQLEILSPSRSARVQFH-LMELNRSVCLECPEFQIPWFHD 683
L+A+ F+I+FL S+ + F L+ +N + LE PE+ P
Sbjct: 425 AELQAVLHPEFHIQFLG---------GKSQKDQNTFQKLLHINATALLEYPEYSGPLLP- 474
Query: 684 RFCQQYNKGIGGMD----GTQQQIFKMLAEVLGGINCVKASVLTPYYHKVDFECILDKRK 739
G +D Q+++ + L +LG + V T Y +D E +LD
Sbjct: 475 --ASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDG 532
Query: 740 KPLP---YGSHNIALGQLPEMPWESNIEIVGSRLPPGAERIALEFLDSKALCRNIPHMKG 796
+ LP + + ++A + P PPG++R+A + + G
Sbjct: 533 EFLPVRDFVAPHLAQPTGSQSP------------PPGSKRLAFLRWEFPNFNSRSKDLLG 580
Query: 797 KSAMKKRHLEILGYRVIQISQFEWNSMALSTKDARMDYLRE 837
+ + +RH+ G+ ++ + +EW + L ++ + YL++
Sbjct: 581 RFVLARRHIVAAGFLIVDVPFYEW--LELKSEWQKGAYLKD 619
>gi|40217810 cell cycle progression 2 protein isoform 2 [Homo
sapiens]
Length = 521
Score = 68.9 bits (167), Expect = 2e-11
Identities = 81/379 (21%), Positives = 168/379 (44%), Gaps = 46/379 (12%)
Query: 474 AKQLKLLQKLDHYGRQRLQHSNSLDLLRKELKSLKGNTFPESLLEEMIATLQHFMDDINY 533
+K+L+ +++ + ++L++ + L L + +L + LL E++ L+ +I
Sbjct: 162 SKELQSVEQEVRWRMRKLKYKH-LAFLAESCATLSQEQHSQELLAELLTHLERRWTEIED 220
Query: 534 INVGEIASFISSTDYLSTLLLDRIASVAVQQIEKIHPFTIP---AIIRPFSVLNYDPPQR 590
+ + + + +LS L++R+ V + + T+P +++ F+ LN+ P Q
Sbjct: 221 SHT--LVTVMMKVGHLSEPLMNRLEDKHV--LNRAQDITLPHLCSVLLAFARLNFHPDQE 276
Query: 591 DEFLGTCVQHLNSYLGILDPFILVFLGFSLATLEYFPEDLLKAI----FNIKFLARLDSQ 646
D+F + L S L L+P + V L ++L L+ E L+A+ F+I+FL
Sbjct: 277 DQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLG----- 331
Query: 647 LEILSPSRSARVQFH-LMELNRSVCLECPEFQIPWFHDRFCQQYNKGIGGMD----GTQQ 701
S+ + F L+ +N + LE PE+ P G +D Q+
Sbjct: 332 ----GKSQKDQNTFQKLLHINATALLEYPEYSGPLLP---ASAVAPGPSALDRKVTPLQK 384
Query: 702 QIFKMLAEVLGGINCVKASVLTPYYHKVDFECILDKRKKPLP---YGSHNIALGQLPEMP 758
++ + L +LG + V T Y +D E +LD + LP + + ++A + P
Sbjct: 385 ELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVRDFVAPHLAQPTGSQSP 444
Query: 759 WESNIEIVGSRLPPGAERIALEFLDSKALCRNIPHMKGKSAMKKRHLEILGYRVIQISQF 818
PPG++R+A + + G+ + +RH+ G+ ++ + +
Sbjct: 445 ------------PPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGFLIVDVPFY 492
Query: 819 EWNSMALSTKDARMDYLRE 837
EW + L ++ + YL++
Sbjct: 493 EW--LELKSEWQKGAYLKD 509
>gi|13569848 cell cycle progression 2 protein isoform 2 [Homo
sapiens]
Length = 521
Score = 68.9 bits (167), Expect = 2e-11
Identities = 81/379 (21%), Positives = 168/379 (44%), Gaps = 46/379 (12%)
Query: 474 AKQLKLLQKLDHYGRQRLQHSNSLDLLRKELKSLKGNTFPESLLEEMIATLQHFMDDINY 533
+K+L+ +++ + ++L++ + L L + +L + LL E++ L+ +I
Sbjct: 162 SKELQSVEQEVRWRMRKLKYKH-LAFLAESCATLSQEQHSQELLAELLTHLERRWTEIED 220
Query: 534 INVGEIASFISSTDYLSTLLLDRIASVAVQQIEKIHPFTIP---AIIRPFSVLNYDPPQR 590
+ + + + +LS L++R+ V + + T+P +++ F+ LN+ P Q
Sbjct: 221 SHT--LVTVMMKVGHLSEPLMNRLEDKHV--LNRAQDITLPHLCSVLLAFARLNFHPDQE 276
Query: 591 DEFLGTCVQHLNSYLGILDPFILVFLGFSLATLEYFPEDLLKAI----FNIKFLARLDSQ 646
D+F + L S L L+P + V L ++L L+ E L+A+ F+I+FL
Sbjct: 277 DQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLG----- 331
Query: 647 LEILSPSRSARVQFH-LMELNRSVCLECPEFQIPWFHDRFCQQYNKGIGGMD----GTQQ 701
S+ + F L+ +N + LE PE+ P G +D Q+
Sbjct: 332 ----GKSQKDQNTFQKLLHINATALLEYPEYSGPLLP---ASAVAPGPSALDRKVTPLQK 384
Query: 702 QIFKMLAEVLGGINCVKASVLTPYYHKVDFECILDKRKKPLP---YGSHNIALGQLPEMP 758
++ + L +LG + V T Y +D E +LD + LP + + ++A + P
Sbjct: 385 ELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVRDFVAPHLAQPTGSQSP 444
Query: 759 WESNIEIVGSRLPPGAERIALEFLDSKALCRNIPHMKGKSAMKKRHLEILGYRVIQISQF 818
PPG++R+A + + G+ + +RH+ G+ ++ + +
Sbjct: 445 ------------PPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGFLIVDVPFY 492
Query: 819 EWNSMALSTKDARMDYLRE 837
EW + L ++ + YL++
Sbjct: 493 EW--LELKSEWQKGAYLKD 509
>gi|209969832 FAST kinase domains 2 [Homo sapiens]
Length = 710
Score = 57.4 bits (137), Expect = 6e-08
Identities = 64/287 (22%), Positives = 116/287 (40%), Gaps = 54/287 (18%)
Query: 553 LLDRIASVAVQQIEKIHPFTIPAIIRPFSVLN--YDPPQRDEFLGTCVQHLNSYLGILDP 610
L+D V+ E ++ I +I+ +S LN Y +++F+ L YL +
Sbjct: 436 LMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISS 495
Query: 611 FILVFLGFSLATLEYFPEDLLKAIFNIKFLARLDSQLEILSPSRSARVQFHLMELN---- 666
L+ +S + YFP A FN + S+L + S + H ++
Sbjct: 496 ENLLDAVYSFCLMNYFP----LAPFNQLLQKDIISEL-LTSDDMKNAYKLHTLDTCLKLD 550
Query: 667 -----RSVCLECPEF--QIPWFHDRFCQQYNKGIGGMDGTQQQIFKMLAEVLGGINCVKA 719
R + L P+ ++P H T ++ ++L+ +LGG
Sbjct: 551 DTVYLRDIALSLPQLPRELPSSH----------------TNAKVAEVLSSLLGGEGHFSK 594
Query: 720 SVLTPYYHKVDFECILD-KRKKPLPYGSHNIALGQLPEMPWESNIEIVGSRLPPGAERIA 778
V P+ + +DFE +D R + LP L ++ S +I +R+A
Sbjct: 595 DVHLPHNYHIDFEIRMDTNRNQVLP----------LSDVDTTSATDI---------QRVA 635
Query: 779 LEFLDSKALCRNIPHMKGKSAMKKRHLEILGYRVIQISQFEWNSMAL 825
+ + A C H +G AMK RHL +G+ VI ++ +E + + +
Sbjct: 636 VLCVSRSAYCLGSSHPRGFLAMKMRHLNAMGFHVILVNNWEMDKLEM 682
Score = 35.0 bits (79), Expect = 0.29
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 7/217 (3%)
Query: 72 FDMLWKLQKQKTSLLKNAE--YVRDHPQFLTLHNLATNKFKLMNDDTLVNVLYVTQQFAG 129
F +W + K+ + K E + HP F L + K+M L+ L+ +
Sbjct: 185 FTAMWTIAKRLSDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGI 244
Query: 130 EAHDPLVEALVTEAWRRLERFDIKLLSEFSSCLADQH--LYFSPLMGKIADIVHRNLETT 187
+ LV+ L+ R+ D LS S+ L L +V + +
Sbjct: 245 PQNTILVQTLLRVTQERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQVWKI 304
Query: 188 QDLSSLSVLMVNISSLISRHFQQQLVNKTELLFDTIDSSEVNVAKSIAKFLRNVRYRYQP 247
+D+ +L V+M I +++L K +D V ++ + + L + +R
Sbjct: 305 EDVFTLQVVMKCIGKDAPIALKRKLEMKA---LRELDRFSVLNSQHMFEVLAAMNHRSLI 361
Query: 248 LLERCNNVFLSNVDHLDLDSISKILSVYKFLQFNSFE 284
LL+ C+ V L N+ L + IL K LQ+++ +
Sbjct: 362 LLDECSKVVLDNIHGCPLRIMINILQSCKDLQYHNLD 398
>gi|209969830 FAST kinase domains 2 [Homo sapiens]
Length = 710
Score = 57.4 bits (137), Expect = 6e-08
Identities = 64/287 (22%), Positives = 116/287 (40%), Gaps = 54/287 (18%)
Query: 553 LLDRIASVAVQQIEKIHPFTIPAIIRPFSVLN--YDPPQRDEFLGTCVQHLNSYLGILDP 610
L+D V+ E ++ I +I+ +S LN Y +++F+ L YL +
Sbjct: 436 LMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISS 495
Query: 611 FILVFLGFSLATLEYFPEDLLKAIFNIKFLARLDSQLEILSPSRSARVQFHLMELN---- 666
L+ +S + YFP A FN + S+L + S + H ++
Sbjct: 496 ENLLDAVYSFCLMNYFP----LAPFNQLLQKDIISEL-LTSDDMKNAYKLHTLDTCLKLD 550
Query: 667 -----RSVCLECPEF--QIPWFHDRFCQQYNKGIGGMDGTQQQIFKMLAEVLGGINCVKA 719
R + L P+ ++P H T ++ ++L+ +LGG
Sbjct: 551 DTVYLRDIALSLPQLPRELPSSH----------------TNAKVAEVLSSLLGGEGHFSK 594
Query: 720 SVLTPYYHKVDFECILD-KRKKPLPYGSHNIALGQLPEMPWESNIEIVGSRLPPGAERIA 778
V P+ + +DFE +D R + LP L ++ S +I +R+A
Sbjct: 595 DVHLPHNYHIDFEIRMDTNRNQVLP----------LSDVDTTSATDI---------QRVA 635
Query: 779 LEFLDSKALCRNIPHMKGKSAMKKRHLEILGYRVIQISQFEWNSMAL 825
+ + A C H +G AMK RHL +G+ VI ++ +E + + +
Sbjct: 636 VLCVSRSAYCLGSSHPRGFLAMKMRHLNAMGFHVILVNNWEMDKLEM 682
Score = 35.0 bits (79), Expect = 0.29
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 7/217 (3%)
Query: 72 FDMLWKLQKQKTSLLKNAE--YVRDHPQFLTLHNLATNKFKLMNDDTLVNVLYVTQQFAG 129
F +W + K+ + K E + HP F L + K+M L+ L+ +
Sbjct: 185 FTAMWTIAKRLSDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGI 244
Query: 130 EAHDPLVEALVTEAWRRLERFDIKLLSEFSSCLADQH--LYFSPLMGKIADIVHRNLETT 187
+ LV+ L+ R+ D LS S+ L L +V + +
Sbjct: 245 PQNTILVQTLLRVTQERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQVWKI 304
Query: 188 QDLSSLSVLMVNISSLISRHFQQQLVNKTELLFDTIDSSEVNVAKSIAKFLRNVRYRYQP 247
+D+ +L V+M I +++L K +D V ++ + + L + +R
Sbjct: 305 EDVFTLQVVMKCIGKDAPIALKRKLEMKA---LRELDRFSVLNSQHMFEVLAAMNHRSLI 361
Query: 248 LLERCNNVFLSNVDHLDLDSISKILSVYKFLQFNSFE 284
LL+ C+ V L N+ L + IL K LQ+++ +
Sbjct: 362 LLDECSKVVLDNIHGCPLRIMINILQSCKDLQYHNLD 398
>gi|45267832 FAST kinase domains 2 [Homo sapiens]
Length = 710
Score = 57.4 bits (137), Expect = 6e-08
Identities = 64/287 (22%), Positives = 116/287 (40%), Gaps = 54/287 (18%)
Query: 553 LLDRIASVAVQQIEKIHPFTIPAIIRPFSVLN--YDPPQRDEFLGTCVQHLNSYLGILDP 610
L+D V+ E ++ I +I+ +S LN Y +++F+ L YL +
Sbjct: 436 LMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISS 495
Query: 611 FILVFLGFSLATLEYFPEDLLKAIFNIKFLARLDSQLEILSPSRSARVQFHLMELN---- 666
L+ +S + YFP A FN + S+L + S + H ++
Sbjct: 496 ENLLDAVYSFCLMNYFP----LAPFNQLLQKDIISEL-LTSDDMKNAYKLHTLDTCLKLD 550
Query: 667 -----RSVCLECPEF--QIPWFHDRFCQQYNKGIGGMDGTQQQIFKMLAEVLGGINCVKA 719
R + L P+ ++P H T ++ ++L+ +LGG
Sbjct: 551 DTVYLRDIALSLPQLPRELPSSH----------------TNAKVAEVLSSLLGGEGHFSK 594
Query: 720 SVLTPYYHKVDFECILD-KRKKPLPYGSHNIALGQLPEMPWESNIEIVGSRLPPGAERIA 778
V P+ + +DFE +D R + LP L ++ S +I +R+A
Sbjct: 595 DVHLPHNYHIDFEIRMDTNRNQVLP----------LSDVDTTSATDI---------QRVA 635
Query: 779 LEFLDSKALCRNIPHMKGKSAMKKRHLEILGYRVIQISQFEWNSMAL 825
+ + A C H +G AMK RHL +G+ VI ++ +E + + +
Sbjct: 636 VLCVSRSAYCLGSSHPRGFLAMKMRHLNAMGFHVILVNNWEMDKLEM 682
Score = 35.0 bits (79), Expect = 0.29
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 7/217 (3%)
Query: 72 FDMLWKLQKQKTSLLKNAE--YVRDHPQFLTLHNLATNKFKLMNDDTLVNVLYVTQQFAG 129
F +W + K+ + K E + HP F L + K+M L+ L+ +
Sbjct: 185 FTAMWTIAKRLSDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGI 244
Query: 130 EAHDPLVEALVTEAWRRLERFDIKLLSEFSSCLADQH--LYFSPLMGKIADIVHRNLETT 187
+ LV+ L+ R+ D LS S+ L L +V + +
Sbjct: 245 PQNTILVQTLLRVTQERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQVWKI 304
Query: 188 QDLSSLSVLMVNISSLISRHFQQQLVNKTELLFDTIDSSEVNVAKSIAKFLRNVRYRYQP 247
+D+ +L V+M I +++L K +D V ++ + + L + +R
Sbjct: 305 EDVFTLQVVMKCIGKDAPIALKRKLEMKA---LRELDRFSVLNSQHMFEVLAAMNHRSLI 361
Query: 248 LLERCNNVFLSNVDHLDLDSISKILSVYKFLQFNSFE 284
LL+ C+ V L N+ L + IL K LQ+++ +
Sbjct: 362 LLDECSKVVLDNIHGCPLRIMINILQSCKDLQYHNLD 398
>gi|5729822 Fas-activated serine/threonine kinase isoform 1 [Homo
sapiens]
Length = 549
Score = 41.6 bits (96), Expect = 0.003
Identities = 58/268 (21%), Positives = 106/268 (39%), Gaps = 14/268 (5%)
Query: 553 LLDRIASVAVQQIEKIHPFTIPAIIRPFSVLNYDPPQRDEFLGTCVQHLNSYLGILDPFI 612
LL+ IA V Q ++ + ++ PF LNY P ++ +F+ C++ + + + P
Sbjct: 257 LLEAIAHFLVVQETQLSSKVVQKLVLPFGRLNYLPLEQ-QFM-PCLERILAREAGVAPLA 314
Query: 613 LVFLGFSLATLEYFPEDLLKAIFNIKFLARLDSQLEILSPSRSARVQFHLMELNRSVCLE 672
V + SL L P L +F+ F+ + L R +L L+ +V LE
Sbjct: 315 TVNILMSLCQLRCLPFRALHFVFSPGFINYISGTPHALIVRR------YLSLLDTAVELE 368
Query: 673 CPEFQIPWFHDR-----FCQQYNKGIGGMDGTQQQIFKMLAEVLGGINCVKASVLTPYYH 727
P ++ P R F Q + + I L G + + P +
Sbjct: 369 LPGYRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLRQLLGEEKYRQDLTVPPGY 428
Query: 728 KVDFECILDKRKKPLPYGSHNIALGQLPEMPWESNIEIVGSRLPPGAERIALEFLDSKAL 787
DF LP + + L P + + P A+R+ L +
Sbjct: 429 CTDFLLCASSSGAVLPVRTQDPFLPYPPRSCPQGQAASSATTRDP-AQRVVLVLRERWHF 487
Query: 788 CRNIPHMKGKSAMKKRHLEILGYRVIQI 815
CR+ + G A+++RHL ++GY+++ +
Sbjct: 488 CRDGRVLLGSRALRERHLGLMGYQLLPL 515
>gi|39995107 Fas-activated serine/threonine kinase isoform 4 [Homo
sapiens]
Length = 408
Score = 41.6 bits (96), Expect = 0.003
Identities = 58/268 (21%), Positives = 106/268 (39%), Gaps = 14/268 (5%)
Query: 553 LLDRIASVAVQQIEKIHPFTIPAIIRPFSVLNYDPPQRDEFLGTCVQHLNSYLGILDPFI 612
LL+ IA V Q ++ + ++ PF LNY P ++ +F+ C++ + + + P
Sbjct: 116 LLEAIAHFLVVQETQLSSKVVQKLVLPFGRLNYLPLEQ-QFM-PCLERILAREAGVAPLA 173
Query: 613 LVFLGFSLATLEYFPEDLLKAIFNIKFLARLDSQLEILSPSRSARVQFHLMELNRSVCLE 672
V + SL L P L +F+ F+ + L R +L L+ +V LE
Sbjct: 174 TVNILMSLCQLRCLPFRALHFVFSPGFINYISGTPHALIVRR------YLSLLDTAVELE 227
Query: 673 CPEFQIPWFHDR-----FCQQYNKGIGGMDGTQQQIFKMLAEVLGGINCVKASVLTPYYH 727
P ++ P R F Q + + I L G + + P +
Sbjct: 228 LPGYRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLRQLLGEEKYRQDLTVPPGY 287
Query: 728 KVDFECILDKRKKPLPYGSHNIALGQLPEMPWESNIEIVGSRLPPGAERIALEFLDSKAL 787
DF LP + + L P + + P A+R+ L +
Sbjct: 288 CTDFLLCASSSGAVLPVRTQDPFLPYPPRSCPQGQAASSATTRDP-AQRVVLVLRERWHF 346
Query: 788 CRNIPHMKGKSAMKKRHLEILGYRVIQI 815
CR+ + G A+++RHL ++GY+++ +
Sbjct: 347 CRDGRVLLGSRALRERHLGLMGYQLLPL 374
>gi|126032350 protein kinase, DNA-activated, catalytic polypeptide
isoform 2 [Homo sapiens]
Length = 4097
Score = 35.4 bits (80), Expect = 0.22
Identities = 31/143 (21%), Positives = 67/143 (46%), Gaps = 26/143 (18%)
Query: 156 SEFSSCLADQHLYFSPLMGKIADIVHRNLETTQD-LSSLSVLMVNISSLISRHFQQQLVN 214
S+FS+CL D ++ ++ K H N+E + LS+L + +S++++++ + N
Sbjct: 280 SQFSTCLLDNYVSLFEVLLKWC--AHTNVELKKAALSALESFLKQVSNMVAKNAEMHK-N 336
Query: 215 KTELLFD-------TIDSSEVNVAKSIAKF-----------LRNVRYRYQPLLERCNNVF 256
K + + +DS+ ++ +I + ++V + Y L++RC +F
Sbjct: 337 KLQYFMEQFYGIIRNVDSNNKELSIAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMF 396
Query: 257 LSNVDHLDLDSISKILSVYKFLQ 279
L+ D D ++ + FLQ
Sbjct: 397 LTQTDTGD----DRVYQMPSFLQ 415
>gi|13654237 protein kinase, DNA-activated, catalytic polypeptide
isoform 1 [Homo sapiens]
Length = 4128
Score = 35.4 bits (80), Expect = 0.22
Identities = 31/143 (21%), Positives = 67/143 (46%), Gaps = 26/143 (18%)
Query: 156 SEFSSCLADQHLYFSPLMGKIADIVHRNLETTQD-LSSLSVLMVNISSLISRHFQQQLVN 214
S+FS+CL D ++ ++ K H N+E + LS+L + +S++++++ + N
Sbjct: 280 SQFSTCLLDNYVSLFEVLLKWC--AHTNVELKKAALSALESFLKQVSNMVAKNAEMHK-N 336
Query: 215 KTELLFD-------TIDSSEVNVAKSIAKF-----------LRNVRYRYQPLLERCNNVF 256
K + + +DS+ ++ +I + ++V + Y L++RC +F
Sbjct: 337 KLQYFMEQFYGIIRNVDSNNKELSIAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMF 396
Query: 257 LSNVDHLDLDSISKILSVYKFLQ 279
L+ D D ++ + FLQ
Sbjct: 397 LTQTDTGD----DRVYQMPSFLQ 415
>gi|113430845 PREDICTED: similar to protein kinase, DNA-activated,
catalytic polypeptide [Homo sapiens]
Length = 4096
Score = 35.0 bits (79), Expect = 0.29
Identities = 31/143 (21%), Positives = 67/143 (46%), Gaps = 26/143 (18%)
Query: 156 SEFSSCLADQHLYFSPLMGKIADIVHRNLETTQD-LSSLSVLMVNISSLISRHFQQQLVN 214
S+FS+CL D ++ ++ K H N+E + LS+L + +S++++++ + N
Sbjct: 280 SQFSTCLLDNYVSLFEVLLKWC--AHTNVELKKAALSALESFLKQVSNMVAKNAEMHK-N 336
Query: 215 KTELLFD-------TIDSSEVNVAKSIAKF-----------LRNVRYRYQPLLERCNNVF 256
K + + +DS+ ++ +I + ++V + Y L++RC +F
Sbjct: 337 KLQYFMEQFYGIIRNVDSNNKELSIAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMF 396
Query: 257 LSNVDHLDLDSISKILSVYKFLQ 279
L+ D D ++ + FLQ
Sbjct: 397 LTQTDTGDY----RVYQMPSFLQ 415
>gi|112293287 tudor domain containing 7 [Homo sapiens]
Length = 1098
Score = 33.5 bits (75), Expect = 0.85
Identities = 35/164 (21%), Positives = 68/164 (41%), Gaps = 12/164 (7%)
Query: 181 HRNLETTQDLSSLSVLMVNISSLISRHFQQQLVNKTELLFDTIDSSEVNVAKSIAKFLRN 240
H + T S + L + +SR +++ ++ L T++ V S +
Sbjct: 180 HVTMSTNNRFSPKASLQPPLQMHLSRTSTKEM---SDNLNQTVEKPNVKPPASYTYKMDE 236
Query: 241 VRYRYQPLLERCNN-VFLSNVDHLDLDSISKILSVYKFLQFNSFEFIIMAKKKLTEMIPL 299
V+ R + +L + NN +++S + H + + L+ QF + I +K + L
Sbjct: 237 VQNRIKEILNKHNNGIWISKLPHFYKELYKEDLNQGILQQFEHWPHICTVEKPCSGGQDL 296
Query: 300 CNHPASFVKLF--------VALGPIAGPEEKKQLKSTMLLMSED 335
+PA +L V L P+ GP++ LK +M+ D
Sbjct: 297 LLYPAKRKQLLRSELDTEKVPLSPLPGPKQTPPLKGCPTVMAGD 340
>gi|12597641 leucine rich repeat containing 19 [Homo sapiens]
Length = 370
Score = 32.7 bits (73), Expect = 1.5
Identities = 40/182 (21%), Positives = 75/182 (41%), Gaps = 20/182 (10%)
Query: 358 LIKRVTSVLHKHLDG-YKPLELLKITQELTFLHFQRKEFFA--KLRELLLSYLKNSFIPT 414
LI+ ++LH + G LE+L I + ++ Q+ F KL++L L K +
Sbjct: 80 LIENKVTILHNNGFGNLSSLEILNICRNSIYV-IQQGAFLGLNKLKQLYLCQNKIEQLNA 138
Query: 415 EVSVLVRAISLLPSP-----HLDEVGISRIEAVLPQCDLNNLSSFATSVLRWIQHDHMYL 469
+V V +R++ LL +LD + +E + +L N S ++ W+ ++ L
Sbjct: 139 DVFVPLRSLKLLNLQGNLISYLDVPPLFHLELITLYGNLWNCSCSLFNLQNWLNTSNVTL 198
Query: 470 DNMTAKQLKLLQKLDHYGRQRLQHSNSLDLLRKELKSLKGNTFPESLLEEMIATLQHFMD 529
+N L Y + + H K+ + FP S+ E++ Q +
Sbjct: 199 ENENITMCSYPNSLQSYNIKTVPH-----------KAECHSKFPSSVTEDLYIHFQPISN 247
Query: 530 DI 531
I
Sbjct: 248 SI 249
>gi|157694513 leucine-rich repeat-containing G protein-coupled
receptor 4 [Homo sapiens]
Length = 951
Score = 32.3 bits (72), Expect = 1.9
Identities = 50/223 (22%), Positives = 90/223 (40%), Gaps = 16/223 (7%)
Query: 335 DLTGEQALAVLGAMGDMESRNSCLIKRVTSVLHKHLDGYKPLELLKIT-QELTFLHFQRK 393
D +G+ AV + + +T + + LE L++ +L+F+H
Sbjct: 42 DCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIH---P 98
Query: 394 EFFAKLRELLLSYLKNSFIPTEVSVLVRAISLLPSPHLDEVGISRI--EAVLPQCDLNNL 451
+ + L+EL + L+N+ + T S +R +S L S LD I+ + ++ L +L
Sbjct: 99 KALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHL 158
Query: 452 SSFATSVLRWIQHDHMYLDNMTAKQLKL--LQKLDHYGRQRLQHSNSLDLLRKELKSLKG 509
S+ H L + A L L + + + L L L +++SL
Sbjct: 159 WLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQ 218
Query: 510 NTFPESLLEEMIATLQHFMDDINYINVGEIASFISSTDYLSTL 552
+ F + + TL D+NY N+GE I + L L
Sbjct: 219 HCFDGL---DNLETL-----DLNYNNLGEFPQAIKALPSLKEL 253
>gi|148277106 hypothetical protein LOC442213 [Homo sapiens]
Length = 829
Score = 31.2 bits (69), Expect = 4.2
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Query: 525 QHFMDDINYINVGEIASFISSTDYLSTLLLDRIASVAVQQIEKIHPFTIPAIIRPFSVLN 584
QHF +DI + G+ ++ I+S YL + +EK+ P ++ IR F V N
Sbjct: 569 QHFRNDIIFSKAGDESNIIASRLYLVARTSRDKQKEITEVLEKLRPLSLSKSIR-FIVFN 627
Query: 585 YDPPQRDEF-LGTCVQHLNSYLGILDPFILVF 615
D + L V L + G+L IL F
Sbjct: 628 PSFVFMDHYSLSVTVPVLIAGFGVLLVLILTF 659
>gi|71143104 potassium channel tetramerisation domain containing 21
[Homo sapiens]
Length = 260
Score = 31.2 bits (69), Expect = 4.2
Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 619 SLATLEYFPEDLLKAIFNIKFLARLDSQLEILSPSRSARVQFHLMELNRSVCLECPE 675
SLATL FP+ +L A+F+ K + DSQ R +V +++ R+ L+ PE
Sbjct: 17 SLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFI-DRDGKVFRYILNFLRTSHLDLPE 72
>gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2
[Homo sapiens]
Length = 1065
Score = 30.8 bits (68), Expect = 5.5
Identities = 48/186 (25%), Positives = 78/186 (41%), Gaps = 29/186 (15%)
Query: 362 VTSVLHKHLDGYKPLELLKITQE-LTFLHFQRKEFFAKLRELLLSYLKNSFIPTEVSVLV 420
+T V L G + L+ L ++Q + + EF +L EL LSY N + S V
Sbjct: 275 LTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSY--NQLTRLDESAFV 332
Query: 421 RAISLLPSPHLDEV-------GISRIEAVLPQCDLNNLSSFATSVLRWIQHDHMY----L 469
+SLL +L + G+ R + L DL N + + W D L
Sbjct: 333 -GLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRN------NEISWAIEDASEAFAGL 385
Query: 470 DNMT-----AKQLKLLQKLDHYGRQRLQHSNSLDLLRKELKSLKGNTFPESLLEEMIATL 524
++T Q+K + K G + L+H LDL + S++ N F ++ L+E+I
Sbjct: 386 TSLTKLILQGNQIKSITKKAFIGLESLEH---LDLNNNAIMSIQENAFSQTHLKELILNT 442
Query: 525 QHFMDD 530
+ D
Sbjct: 443 SSLLCD 448
>gi|239754394 PREDICTED: hypothetical protein XP_002345990 [Homo
sapiens]
Length = 128
Score = 30.4 bits (67), Expect = 7.2
Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Query: 325 LKSTMLLMSEDLTGEQALAV-LGAMGDMESRNSCLIKRVTSVLHKHLDGYKPLELLKITQ 383
L LLM++ G Q+L + L +E +SC I + + KHL + L+L K +
Sbjct: 43 LSEQFLLMAD--WGVQSLCIKLSGWESIEESSSCQIILFSQIPLKHLSSFLDLDLAKYLK 100
Query: 384 ELTFLHFQRK 393
LT L QR+
Sbjct: 101 PLTDLLPQRR 110
>gi|239748968 PREDICTED: hypothetical protein XP_002346842 [Homo
sapiens]
Length = 128
Score = 30.4 bits (67), Expect = 7.2
Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Query: 325 LKSTMLLMSEDLTGEQALAV-LGAMGDMESRNSCLIKRVTSVLHKHLDGYKPLELLKITQ 383
L LLM++ G Q+L + L +E +SC I + + KHL + L+L K +
Sbjct: 43 LSEQFLLMAD--WGVQSLCIKLSGWESIEESSSCQIILFSQIPLKHLSSFLDLDLAKYLK 100
Query: 384 ELTFLHFQRK 393
LT L QR+
Sbjct: 101 PLTDLLPQRR 110
>gi|239742990 PREDICTED: hypothetical protein XP_002342728 [Homo
sapiens]
Length = 128
Score = 30.4 bits (67), Expect = 7.2
Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Query: 325 LKSTMLLMSEDLTGEQALAV-LGAMGDMESRNSCLIKRVTSVLHKHLDGYKPLELLKITQ 383
L LLM++ G Q+L + L +E +SC I + + KHL + L+L K +
Sbjct: 43 LSEQFLLMAD--WGVQSLCIKLSGWESIEESSSCQIILFSQIPLKHLSSFLDLDLAKYLK 100
Query: 384 ELTFLHFQRK 393
LT L QR+
Sbjct: 101 PLTDLLPQRR 110
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,201,602
Number of Sequences: 37866
Number of extensions: 1209403
Number of successful extensions: 3784
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3716
Number of HSP's gapped (non-prelim): 51
length of query: 847
length of database: 18,247,518
effective HSP length: 111
effective length of query: 736
effective length of database: 14,044,392
effective search space: 10336672512
effective search space used: 10336672512
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.