Guide to the Human Genome
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Search of human proteins with 187761343

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
         (576 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]      1177   0.0  
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]      1177   0.0  
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H...   133   4e-31
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s...   130   3e-30
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho...   129   1e-29
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H...   123   4e-28
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [...   122   7e-28
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [...   122   7e-28
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]       114   2e-25
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H...   110   3e-24
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC...   109   6e-24
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC...   109   6e-24
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso...   103   6e-22
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo...   103   6e-22
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom...    98   2e-20
gi|57165410 acyl-CoA synthetase long-chain family member 6 isofo...    90   6e-18
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo...    89   1e-17
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo...    89   1e-17
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo...    89   1e-17
gi|57165412 acyl-CoA synthetase long-chain family member 6 isofo...    88   2e-17
gi|13325057 solute carrier family 27 (fatty acid transporter), m...    87   5e-17
gi|13236579 solute carrier family 27 member 3 [Homo sapiens]           85   2e-16
gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo...    82   2e-15
gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]     75   2e-13
gi|27477105 lipidosin [Homo sapiens]                                   72   2e-12
gi|38524616 solute carrier family 27, member 1 [Homo sapiens]          71   2e-12
gi|227499619 solute carrier family 27 (fatty acid transporter), ...    70   5e-12
gi|13375727 acyl-CoA synthetase short-chain family member 3 [Hom...    70   7e-12
gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens]     68   3e-11
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s...    67   3e-11

>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score = 1177 bits (3046), Expect = 0.0
 Identities = 576/576 (100%), Positives = 576/576 (100%)

Query: 1   MLPHVVLTFRRLGCALASCRLAPARHRGSGLLHTAPVARSDRSAPVFTRALAFGDRIALV 60
           MLPHVVLTFRRLGCALASCRLAPARHRGSGLLHTAPVARSDRSAPVFTRALAFGDRIALV
Sbjct: 1   MLPHVVLTFRRLGCALASCRLAPARHRGSGLLHTAPVARSDRSAPVFTRALAFGDRIALV 60

Query: 61  DQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGG 120
           DQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGG
Sbjct: 61  DQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGG 120

Query: 121 VAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVE 180
           VAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVE
Sbjct: 121 VAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVE 180

Query: 181 EPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILH 240
           EPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILH
Sbjct: 181 EPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILH 240

Query: 241 VLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKL 300
           VLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKL
Sbjct: 241 VLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKL 300

Query: 301 MEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI 360
           MEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI
Sbjct: 301 MEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI 360

Query: 361 GMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEE 420
           GMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEE
Sbjct: 361 GMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEE 420

Query: 421 KEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTG 480
           KEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTG
Sbjct: 421 KEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTG 480

Query: 481 GYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNV 540
           GYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNV
Sbjct: 481 GYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNV 540

Query: 541 LAPYAVPSELVLVEEIPRNQMGKIDKKALIRHFHPS 576
           LAPYAVPSELVLVEEIPRNQMGKIDKKALIRHFHPS
Sbjct: 541 LAPYAVPSELVLVEEIPRNQMGKIDKKALIRHFHPS 576


>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score = 1177 bits (3046), Expect = 0.0
 Identities = 576/576 (100%), Positives = 576/576 (100%)

Query: 1   MLPHVVLTFRRLGCALASCRLAPARHRGSGLLHTAPVARSDRSAPVFTRALAFGDRIALV 60
           MLPHVVLTFRRLGCALASCRLAPARHRGSGLLHTAPVARSDRSAPVFTRALAFGDRIALV
Sbjct: 1   MLPHVVLTFRRLGCALASCRLAPARHRGSGLLHTAPVARSDRSAPVFTRALAFGDRIALV 60

Query: 61  DQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGG 120
           DQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGG
Sbjct: 61  DQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGG 120

Query: 121 VAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVE 180
           VAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVE
Sbjct: 121 VAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVE 180

Query: 181 EPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILH 240
           EPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILH
Sbjct: 181 EPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILH 240

Query: 241 VLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKL 300
           VLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKL
Sbjct: 241 VLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKL 300

Query: 301 MEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI 360
           MEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI
Sbjct: 301 MEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI 360

Query: 361 GMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEE 420
           GMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEE
Sbjct: 361 GMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEE 420

Query: 421 KEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTG 480
           KEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTG
Sbjct: 421 KEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTG 480

Query: 481 GYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNV 540
           GYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNV
Sbjct: 481 GYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNV 540

Query: 541 LAPYAVPSELVLVEEIPRNQMGKIDKKALIRHFHPS 576
           LAPYAVPSELVLVEEIPRNQMGKIDKKALIRHFHPS
Sbjct: 541 LAPYAVPSELVLVEEIPRNQMGKIDKKALIRHFHPS 576


>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
           sapiens]
          Length = 580

 Score =  133 bits (335), Expect = 4e-31
 Identities = 136/525 (25%), Positives = 233/525 (44%), Gaps = 64/525 (12%)

Query: 67  TYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLY 126
           ++REL S S + +  + + CG   GD    R++ +      + +   A   +G + +P  
Sbjct: 90  SFRELGSLSRKAANVLTKPCGLQRGD----RLAVILPRIPEWWLVNVACIRTGIIFMPGT 145

Query: 127 RKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRK---LGVPLLPLTPAIYTG--AVEE 181
            +  A  + Y +  S++  ++AS+E    +  +V +   L   LL ++P  + G  + +E
Sbjct: 146 IQLTAKDILYRLRASKAKCIVASEEVAPAVESIVLECPDLKTKLL-VSPQSWNGWLSFQE 204

Query: 182 PAEVPVPEQGWRNKGAM----IIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKD-D 236
             +    E      G+     I +TSGTTG PK    +  ++    T     W   K  D
Sbjct: 205 LFQFASEEHSCVETGSQEPMTIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYWLDLKSSD 264

Query: 237 VILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPR-INVFMAVPT 295
           +I ++     V   + ++    W+   CV +   + Q   + FL + T   I    + PT
Sbjct: 265 IIWNMSDTGWVKAAIGSVFSS-WLCGACVFVHRMA-QFDTDTFLDTLTTYPITTLCSPPT 322

Query: 296 IYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERY 355
           +Y  L+            Q  L+    + +R  ++G   L   VLE+W+  TG  L E Y
Sbjct: 323 VYRMLV------------QKDLKRYKFKSLRHCLTGGEPLNPEVLEQWRVQTGLELYEGY 370

Query: 356 GMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVT 415
           G TE+GM  +      ++ PGS+G  +    V+I+ EN                 G  + 
Sbjct: 371 GQTEVGMICANQKGQEIK-PGSMGKGMLPYDVQIIDEN-----------------GNVLP 412

Query: 416 PGFEEKEGELLVRGPSV-----FREYWNKPEETKSAFTLDGWFKTGDT-VVFKDGQYWIR 469
           PG   KEGE+ +R         F +Y + P++T +    D ++ TGD  V+  DG +W  
Sbjct: 413 PG---KEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGD-FYVTGDRGVMDSDGYFWFV 468

Query: 470 GRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLS 529
           GR   D+I + GY++   EVE  L+ HP++ + AV+  PD   G+ V A V L       
Sbjct: 469 GRAD-DVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKAFVVLAAPFKSY 527

Query: 530 H-----RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
           +      EL++  +   APY  P ++  V+E+P+   GKI +  L
Sbjct: 528 NPEKLTLELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVL 572


>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
           sapiens]
          Length = 586

 Score =  130 bits (327), Expect = 3e-30
 Identities = 134/531 (25%), Positives = 225/531 (42%), Gaps = 72/531 (13%)

Query: 65  RHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVP 124
           R ++ EL S S + +  +   C    GD    RV  +      + +A  A   +G V +P
Sbjct: 94  RWSFEELGSLSRKFANILSEACSLQRGD----RVILILPRVPEWWLANVACLRTGTVLIP 149

Query: 125 LYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGA------ 178
              +     + Y +  S+++ ++ +    ++L+P V  +      L   +          
Sbjct: 150 GTTQLTQKDILYRLQSSKANCIITN----DVLAPAVDAVASKCENLHSKLIVSENSREGW 205

Query: 179 ------VEEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWA- 231
                 ++  ++     +   N+   I +TSGT+G PK    TH +    ++     W  
Sbjct: 206 GNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLD 265

Query: 232 WTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVM---MPEFSPQQVWEKFLSSETPRIN 288
            T  DV+ +           +++  P W+   CV    +P F P  + +    S+ P I 
Sbjct: 266 LTPSDVMWNTSDTGWAKSAWSSVFSP-WIQGACVFTHHLPRFEPTSILQTL--SKYP-IT 321

Query: 289 VFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITG 348
           VF + PT+Y  L+            Q+ + +   + ++  VS    +   V EKW+N TG
Sbjct: 322 VFCSAPTVYRMLV------------QNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG 369

Query: 349 HTLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGD 408
             + E YG TE  + + G        PGS+G P P   V+IV  N               
Sbjct: 370 LDIYEGYGQTET-VLICGNFKGMKIKPGSMGKPSPAFDVKIVDVN--------------- 413

Query: 409 ERGTKVTPGFEEKEG-ELLVRGP-SVFREYWNKPEETKSAFTLDG-WFKTGDT-VVFKDG 464
             G  + PG E   G ++L   P  +F  Y + P +T S  TL G ++ TGD   + KDG
Sbjct: 414 --GNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTAS--TLRGNFYITGDRGYMDKDG 469

Query: 465 QYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLRE 524
            +W   R   D+I + GY++   EVE  L  HPS+ + AV+  PD   G+ V A V L  
Sbjct: 470 YFWFVARAD-DVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNP 528

Query: 525 GHSLSH------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
            +  SH      +E++E  +   APY  P ++  ++E+P+   GK  +  L
Sbjct: 529 DYK-SHDQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNEL 578


>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
           sapiens]
          Length = 579

 Score =  129 bits (323), Expect = 1e-29
 Identities = 137/530 (25%), Positives = 220/530 (41%), Gaps = 75/530 (14%)

Query: 67  TYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLY 126
           ++ EL  +S + +  +   CG   GD    R+  +      + +   A   +G V +P  
Sbjct: 91  SFEELGKQSRKAANVLGGACGLQPGD----RMMLVLPRLPEWWLVSVACMRTGTVMIPGV 146

Query: 127 RKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVEEPA--- 183
            +     L+Y +  S++  ++ S      L+P V  +      L   +       P    
Sbjct: 147 TQLTEKDLKYRLQASRAKSIITSDS----LAPRVDAISAECPSLQTKLLVSDSSRPGWLN 202

Query: 184 ------EVPVPEQGWRNKGA---MIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW-AWT 233
                 E        R K      I +TSGTTG PK V  +  +          +W A T
Sbjct: 203 FRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALT 262

Query: 234 KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPR--INVFM 291
           + D+  +      V       L   W   +C+ + E    +V  K + +   +  I    
Sbjct: 263 ESDIFWNTTDTGWVKAAWT--LFSAWPNGSCIFVHELP--RVDAKVILNTLSKFPITTLC 318

Query: 292 AVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTL 351
            VPTI+  L+            Q+ L     + +R  ++G  AL   V EKWK+ TG  L
Sbjct: 319 CVPTIFRLLV------------QEDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTGVEL 366

Query: 352 LERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERG 411
            E YG +E  +  + P    ++  GS+G   P   V+IV                 D+ G
Sbjct: 367 YEGYGQSETVVICANPKGMKIK-SGSMGKASPPYDVQIV-----------------DDEG 408

Query: 412 TKVTPGFEEKEGELLVR-GPS----VFREYWNKPEETKSAFTLDGWFKTGDTV-VFKDGQ 465
             + PG   +EG + VR  P+     F  Y + PE+T ++   D ++ TGD   + KDG 
Sbjct: 409 NVLPPG---EEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGD-FYITGDRARMDKDGY 464

Query: 466 YWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREG 525
           +W  GR   D+I +  Y++  +EVE  L  HP++ + AV+  PD   G+ V A + L   
Sbjct: 465 FWFMGRND-DVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPA 523

Query: 526 HSLSH------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
           +S SH      REL+E  + V APY  P ++  V E+P+   GKI +  L
Sbjct: 524 YS-SHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKL 572


>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
           sapiens]
          Length = 577

 Score =  123 bits (309), Expect = 4e-28
 Identities = 129/525 (24%), Positives = 225/525 (42%), Gaps = 67/525 (12%)

Query: 68  YRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYR 127
           +REL   S + +  +   CG   GD    RV+ +      + +       +G + +P   
Sbjct: 83  FRELSENSQQAANVLSGACGLQRGD----RVAVVLPRVPEWWLVILGCIRAGLIFMPGTI 138

Query: 128 KHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRK---LGVPLLPLTPAI-----YTGAV 179
           +  +  + Y +  S++  ++A  E ++ +  V  +   L + LL    +      +   +
Sbjct: 139 QMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLL 198

Query: 180 EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW--AWT---K 234
            E +      +    + + I +TSGT+G PK    ++ ++     GL  K    WT    
Sbjct: 199 NEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSL-----GLKAKMDAGWTGLQA 253

Query: 235 DDVILHVLPLHHVHGVVNALLCPLWVGATCV--MMPEFSPQQVWEKFLSSETPRINVFMA 292
            D++  +     +  ++ +L+ P  +GA     ++P+F P  +  K LSS    I   M 
Sbjct: 254 SDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVIL-KTLSSYP--IKSMMG 310

Query: 293 VPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLL 352
            P +Y  L++     +  PH Q+ +             G + LP   LE W+  TG  + 
Sbjct: 311 APIVYRMLLQQDLSSYKFPHLQNCVTV-----------GESLLP-ETLENWRAQTGLDIR 358

Query: 353 ERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGT 412
           E YG TE G+      T  ++ PG +GT      V+I+                 D++G 
Sbjct: 359 ESYGQTETGLTCMVSKTMKIK-PGYMGTAASCYDVQII-----------------DDKGN 400

Query: 413 KVTPGFEEKEGELL--VRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRG 470
            + PG E   G  +  +R   +F  Y + P++T +    D W      +  +DG +   G
Sbjct: 401 VLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMG 460

Query: 471 RTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSH 530
           R   DII + GY++   EVE  L+ HP++ + AVI  PD   G+ V A V L     LSH
Sbjct: 461 RAD-DIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVL-ASQFLSH 518

Query: 531 ------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
                 +EL++  ++V APY  P ++  V  +P+   GKI +  L
Sbjct: 519 DPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKL 563


>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score =  122 bits (307), Expect = 7e-28
 Identities = 129/526 (24%), Positives = 222/526 (42%), Gaps = 69/526 (13%)

Query: 68  YRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYR 127
           +REL   S + +  +   CG   GD    RV+ +      + +       +G + +P   
Sbjct: 83  FRELSENSQQAANILSGACGLQRGD----RVAVMLPRVPEWWLVILGCIRAGLIFMPGTI 138

Query: 128 KHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRK---LGVPLLPLTPAI-----YTGAV 179
           +  +  + Y +  S++  ++A  E ++ +  V  +   L + LL    +      +   +
Sbjct: 139 QMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLL 198

Query: 180 EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW--AWT---K 234
            E +      +    + + I +TSGT+G PK    ++ ++     GL  K    WT    
Sbjct: 199 NEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSL-----GLKAKMDAGWTGLQA 253

Query: 235 DDVILHVLPLHHVHGVVNALLCPLWVGATCV---MMPEFSPQQVWEKFLSSETPRINVFM 291
            D++  +     +  ++ +LL   W    C    ++P+F P  +  K LSS    I   M
Sbjct: 254 SDIMWTISDTGWILNILGSLL-ESWTLGACTFVHLLPKFDPLVIL-KTLSSYP--IKSMM 309

Query: 292 AVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTL 351
             P +Y  L++     +  PH Q+ L             G + LP   LE W+  TG  +
Sbjct: 310 GAPIVYRMLLQQDLSSYKFPHLQNCL-----------AGGESLLP-ETLENWRAQTGLDI 357

Query: 352 LERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERG 411
            E YG TE G+      T  ++ PG +GT      V+++                 D++G
Sbjct: 358 REFYGQTETGLTCMVSKTMKIK-PGYMGTAASCYDVQVI-----------------DDKG 399

Query: 412 TKVTPGFEEKEGELL--VRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIR 469
             + PG E   G  +  +R   +F  Y   P++T +    D W      +  +DG +   
Sbjct: 400 NVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWLLGDRGIKDEDGYFQFM 459

Query: 470 GRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLS 529
           GR   DII + GY++   EVE  L+ HP++ + AVI  PD   G+ V A V L     LS
Sbjct: 460 GRAD-DIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVIL-ASQFLS 517

Query: 530 H------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
           H      +EL++  ++V APY  P ++  V  +P+   GKI +  L
Sbjct: 518 HDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 563


>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score =  122 bits (307), Expect = 7e-28
 Identities = 129/526 (24%), Positives = 222/526 (42%), Gaps = 69/526 (13%)

Query: 68  YRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYR 127
           +REL   S + +  +   CG   GD    RV+ +      + +       +G + +P   
Sbjct: 83  FRELSENSQQAANILSGACGLQRGD----RVAVMLPRVPEWWLVILGCIRAGLIFMPGTI 138

Query: 128 KHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRK---LGVPLLPLTPAI-----YTGAV 179
           +  +  + Y +  S++  ++A  E ++ +  V  +   L + LL    +      +   +
Sbjct: 139 QMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLL 198

Query: 180 EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW--AWT---K 234
            E +      +    + + I +TSGT+G PK    ++ ++     GL  K    WT    
Sbjct: 199 NEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSL-----GLKAKMDAGWTGLQA 253

Query: 235 DDVILHVLPLHHVHGVVNALLCPLWVGATCV---MMPEFSPQQVWEKFLSSETPRINVFM 291
            D++  +     +  ++ +LL   W    C    ++P+F P  +  K LSS    I   M
Sbjct: 254 SDIMWTISDTGWILNILGSLL-ESWTLGACTFVHLLPKFDPLVIL-KTLSSYP--IKSMM 309

Query: 292 AVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTL 351
             P +Y  L++     +  PH Q+ L             G + LP   LE W+  TG  +
Sbjct: 310 GAPIVYRMLLQQDLSSYKFPHLQNCL-----------AGGESLLP-ETLENWRAQTGLDI 357

Query: 352 LERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERG 411
            E YG TE G+      T  ++ PG +GT      V+++                 D++G
Sbjct: 358 REFYGQTETGLTCMVSKTMKIK-PGYMGTAASCYDVQVI-----------------DDKG 399

Query: 412 TKVTPGFEEKEGELL--VRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIR 469
             + PG E   G  +  +R   +F  Y   P++T +    D W      +  +DG +   
Sbjct: 400 NVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWLLGDRGIKDEDGYFQFM 459

Query: 470 GRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLS 529
           GR   DII + GY++   EVE  L+ HP++ + AVI  PD   G+ V A V L     LS
Sbjct: 460 GRAD-DIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVIL-ASQFLS 517

Query: 530 H------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
           H      +EL++  ++V APY  P ++  V  +P+   GKI +  L
Sbjct: 518 HDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 563


>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
          Length = 615

 Score =  114 bits (285), Expect = 2e-25
 Identities = 141/565 (24%), Positives = 232/565 (41%), Gaps = 88/565 (15%)

Query: 48  TRALAFGDRIALVDQHG--RHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCAND 105
           T A    +R ALV  H   R T+ +L     + +  +  +  C G     +R+     N 
Sbjct: 80  TTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLSIGLCKG-----DRLGMWGPNS 134

Query: 106 ASYVVAQWASWMSGGVAVPLYRKHPAAQLEYVICDSQSSVVL-----ASQEYLELLSPV- 159
            ++V+ Q A+  +G + V +   + A +LEYV+       ++      +Q+Y  +L  + 
Sbjct: 135 YAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQIC 194

Query: 160 ---------------------VRKLGVPL---LPLTPAIYTGAVEEPAEVPVPEQGWRN- 194
                                V  +  PL   L L   +  G+  +  +     Q + + 
Sbjct: 195 PEVENAQPGALKSQRLPDLTTVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSC 254

Query: 195 -KGAMIIYTSGTTGRPKGVLSTHQNI--RAVVTGLVHKWAWTKDDVILHVLP--LHHVHG 249
                I +TSGTTG PKG   +H NI   + + G   K      + +  +LP  L+H  G
Sbjct: 255 HDPINIQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLG 314

Query: 250 VVNALLCPLWVGATCVMM-PEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHF 308
            V   +  L  GAT ++  P F+ ++  E  +S E  R       PT++  ++       
Sbjct: 315 SVAGTMMCLMYGATLILASPIFNGKKALEA-ISRE--RGTFLYGTPTMFVDILN------ 365

Query: 309 TQPHAQDF-LRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSG- 366
            QP    + +  +C      +++GS A P  +      I    L+  YG TE        
Sbjct: 366 -QPDFSSYDISTMCGG----VIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPVTFAH 420

Query: 367 -PLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKV---TPGFEEKE 422
            P  T  +   SVG  +P  + RI++                 E GT     TPG     
Sbjct: 421 FPEDTVEQKAESVGRIMPHTEARIMNM----------------EAGTLAKLNTPG----- 459

Query: 423 GELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKD-GQYWIRGRTSVDIIKTGG 481
            EL +RG  V   YW +P++T+ A   D W+ TGD     + G   I GR S D+I  GG
Sbjct: 460 -ELCIRGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGR-SKDMIIRGG 517

Query: 482 YKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNVL 541
             +   E+E     HP + +V V+GV D   G+ + A + L++G   +  E+K + +  +
Sbjct: 518 ENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRLKDGEETTVEEIKAFCKGKI 577

Query: 542 APYAVPSELVLVEEIPRNQMGKIDK 566
           + + +P  +V V   P    GKI K
Sbjct: 578 SHFKIPKYIVFVTNYPLTISGKIQK 602


>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
           sapiens]
          Length = 577

 Score =  110 bits (276), Expect = 3e-24
 Identities = 106/384 (27%), Positives = 169/384 (44%), Gaps = 48/384 (12%)

Query: 198 MIIYTSGTTGRPKGVLSTHQ-NIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLC 256
           +I +TSGTTG PK    +H   ++    G     +    DV   +     +   +  L+ 
Sbjct: 222 VIFFTSGTTGFPKMAKHSHGLALQPSFPGSRKLRSLKTSDVSWCLSDSGWIVATIWTLVE 281

Query: 257 PLWVGATCVM--MPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQ 314
           P   G T  +  +P+F  + + +  L      IN F  V +IY  +++           Q
Sbjct: 282 PWTAGCTVFIHHLPQFDTKVIIQTLLKYP---INHFWGVSSIYRMILQ-----------Q 327

Query: 315 DFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVRL 374
           DF              G   LP    E+WK  TG  L E YG +E G+  +      ++ 
Sbjct: 328 DFTSIRFPALEHCYTGGEVVLPKDQ-EEWKRRTGLLLYENYGQSETGLICATYWGMKIK- 385

Query: 375 PGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELL--VRGPSV 432
           PG +G   P   V+++                 D++G+ + P  E   G  +  VR  S+
Sbjct: 386 PGFMGKATPPYDVQVI-----------------DDKGSILPPNTEGNIGIRIKPVRPVSL 428

Query: 433 FREYWNKPEETKSAFTLDGWFKTGDT-VVFKDGQYWIRGRTSVDIIKTGGYKVSALEVEW 491
           F  Y   PE+T      D ++ TGD   + ++G     GR+  DII   GY++   EVE 
Sbjct: 429 FMCYEGDPEKTAKVECGD-FYNTGDRGKMDEEGYICFLGRSD-DIINASGYRIGPAEVES 486

Query: 492 HLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSH------RELKEWARNVLAPYA 545
            L+ HP++ + AV+G PD   G+ V A + L     LSH      +EL++  ++V APY 
Sbjct: 487 ALVEHPAVAESAVVGSPDPIRGEVVKAFIVLTP-QFLSHDKDQLTKELQQHVKSVTAPYK 545

Query: 546 VPSELVLVEEIPRNQMGKIDKKAL 569
            P ++  V E+P+   GKI++K L
Sbjct: 546 YPRKVEFVSELPKTITGKIERKEL 569


>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 2 [Homo sapiens]
          Length = 571

 Score =  109 bits (273), Expect = 6e-24
 Identities = 125/526 (23%), Positives = 217/526 (41%), Gaps = 75/526 (14%)

Query: 68  YRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYR 127
           +REL   S + +  +   CG   GD    RV+ +      + +       +G + +P   
Sbjct: 83  FRELSENSQQAANVLSGACGLQRGD----RVAVMLPRVPEWWLVILGCIRAGLIFMPGTI 138

Query: 128 KHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRK---LGVPLLPLTPAI-----YTGAV 179
           +  +  + Y +  S++  ++A  E ++ +  V  +   L + LL    +      +   +
Sbjct: 139 QMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLL 198

Query: 180 EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW--AWT---K 234
            E +      +    + + I +TSGT+G PK    ++ ++     GL  K    WT    
Sbjct: 199 NEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSL-----GLKAKMDAGWTGLQA 253

Query: 235 DDVILHVLPLHHVHGVVNALLCPLWVGATCV---MMPEFSPQQVWEKFLSSETPRINVFM 291
            D++  +     +  ++ +LL   W    C    ++P+F P  +  K LSS    I   M
Sbjct: 254 SDIMWTISDTGWILNILGSLL-ESWTLGACTFVHLLPKFDPLVIL-KTLSSYP--IKSMM 309

Query: 292 AVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTL 351
             P +Y  L++     +  PH Q+ L             G + LP   LE W+  TG  +
Sbjct: 310 GAPIVYRMLLQQDLSSYKFPHLQNCL-----------AGGESLLP-ETLENWRAQTGLDI 357

Query: 352 LERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERG 411
            E YG TE G+      T  ++ PG +GT      V++++           +H       
Sbjct: 358 REFYGQTETGLTCMVSKTMKIK-PGYMGTAASCYDVQVIA----------FVHG------ 400

Query: 412 TKVTPGFEEKEGELLVRGPSV--FREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIR 469
                    + G+L   G     F  +   P++T +    D W      +  +DG +   
Sbjct: 401 -------SPRAGDLGFAGTMTLSFCGHQENPDKTAANIRGDFWLLGDRGIKDEDGYFQFM 453

Query: 470 GRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLS 529
           GR   DII + GY++   EVE  L+ HP++ + AVI  PD   G+ V A V L     LS
Sbjct: 454 GRAD-DIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVIL-ASQFLS 511

Query: 530 H------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
           H      +EL++  ++V APY  P ++  V  +P+   GKI +  L
Sbjct: 512 HDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557


>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 1 [Homo sapiens]
          Length = 571

 Score =  109 bits (273), Expect = 6e-24
 Identities = 125/526 (23%), Positives = 217/526 (41%), Gaps = 75/526 (14%)

Query: 68  YRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYR 127
           +REL   S + +  +   CG   GD    RV+ +      + +       +G + +P   
Sbjct: 83  FRELSENSQQAANVLSGACGLQRGD----RVAVMLPRVPEWWLVILGCIRAGLIFMPGTI 138

Query: 128 KHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRK---LGVPLLPLTPAI-----YTGAV 179
           +  +  + Y +  S++  ++A  E ++ +  V  +   L + LL    +      +   +
Sbjct: 139 QMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLL 198

Query: 180 EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW--AWT---K 234
            E +      +    + + I +TSGT+G PK    ++ ++     GL  K    WT    
Sbjct: 199 NEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSL-----GLKAKMDAGWTGLQA 253

Query: 235 DDVILHVLPLHHVHGVVNALLCPLWVGATCV---MMPEFSPQQVWEKFLSSETPRINVFM 291
            D++  +     +  ++ +LL   W    C    ++P+F P  +  K LSS    I   M
Sbjct: 254 SDIMWTISDTGWILNILGSLL-ESWTLGACTFVHLLPKFDPLVIL-KTLSSYP--IKSMM 309

Query: 292 AVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTL 351
             P +Y  L++     +  PH Q+ L             G + LP   LE W+  TG  +
Sbjct: 310 GAPIVYRMLLQQDLSSYKFPHLQNCL-----------AGGESLLP-ETLENWRAQTGLDI 357

Query: 352 LERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERG 411
            E YG TE G+      T  ++ PG +GT      V++++           +H       
Sbjct: 358 REFYGQTETGLTCMVSKTMKIK-PGYMGTAASCYDVQVIA----------FVHG------ 400

Query: 412 TKVTPGFEEKEGELLVRGPSV--FREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIR 469
                    + G+L   G     F  +   P++T +    D W      +  +DG +   
Sbjct: 401 -------SPRAGDLGFAGTMTLSFCGHQENPDKTAANIRGDFWLLGDRGIKDEDGYFQFM 453

Query: 470 GRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLS 529
           GR   DII + GY++   EVE  L+ HP++ + AVI  PD   G+ V A V L     LS
Sbjct: 454 GRAD-DIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVIL-ASQFLS 511

Query: 530 H------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
           H      +EL++  ++V APY  P ++  V  +P+   GKI +  L
Sbjct: 512 HDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557


>gi|253970489 acyl-CoA synthetase short-chain family member 2
           isoform 2 [Homo sapiens]
          Length = 714

 Score =  103 bits (256), Expect = 6e-22
 Identities = 102/385 (26%), Positives = 168/385 (43%), Gaps = 44/385 (11%)

Query: 199 IIYTSGTTGRPKGVLSTHQNIRA-VVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLCP 257
           I+YTSG+TG+PKGV+ T       V T   + + +  +DV      +  + G       P
Sbjct: 326 ILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGP 385

Query: 258 LWVGATCVMMPEFSPQQVWEKFLSS-ETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDF 316
           L  GAT V+           +  S  +  ++  F   PT    LM++ D   T+      
Sbjct: 386 LANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTK------ 439

Query: 317 LRAVCEEKIRLMVSGSAALPL-PVLEKWKN-ITGHT---LLERYGMTEIGMALSGPLTTA 371
                  +  L V G+   P+ P    W + + G     +++ +  TE G  +  PL  A
Sbjct: 440 -----HSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGA 494

Query: 372 VRL-PGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGP 430
             + PGS   P  GV   I++E+ +          EG+  G  V   F++         P
Sbjct: 495 TPMKPGSATFPFFGVAPAILNESGEE--------LEGEAEGYLV---FKQP-------WP 536

Query: 431 SVFREYWNKPEETKSAF--TLDGWFKTGDTVVF-KDGQYWIRGRTSVDIIKTGGYKVSAL 487
            + R  +   E  ++ +     G++ TGD     +DG YWI GR   D++   G+ +S  
Sbjct: 537 GIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRID-DMLNVSGHLLSTA 595

Query: 488 EVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHR---ELKEWARNVLAPY 544
           EVE  L+ H ++ + AV+G P    G+ +   VTL +GH+ S +   ELK+  R  + P 
Sbjct: 596 EVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPI 655

Query: 545 AVPSELVLVEEIPRNQMGKIDKKAL 569
           A P  +     +P+ + GKI ++ L
Sbjct: 656 ATPDYIQNAPGLPKTRSGKIMRRVL 680


>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
           1 [Homo sapiens]
          Length = 701

 Score =  103 bits (256), Expect = 6e-22
 Identities = 102/385 (26%), Positives = 168/385 (43%), Gaps = 44/385 (11%)

Query: 199 IIYTSGTTGRPKGVLSTHQNIRA-VVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLCP 257
           I+YTSG+TG+PKGV+ T       V T   + + +  +DV      +  + G       P
Sbjct: 313 ILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGP 372

Query: 258 LWVGATCVMMPEFSPQQVWEKFLSS-ETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDF 316
           L  GAT V+           +  S  +  ++  F   PT    LM++ D   T+      
Sbjct: 373 LANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTK------ 426

Query: 317 LRAVCEEKIRLMVSGSAALPL-PVLEKWKN-ITGHT---LLERYGMTEIGMALSGPLTTA 371
                  +  L V G+   P+ P    W + + G     +++ +  TE G  +  PL  A
Sbjct: 427 -----HSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGA 481

Query: 372 VRL-PGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGP 430
             + PGS   P  GV   I++E+ +          EG+  G  V   F++         P
Sbjct: 482 TPMKPGSATFPFFGVAPAILNESGEE--------LEGEAEGYLV---FKQP-------WP 523

Query: 431 SVFREYWNKPEETKSAF--TLDGWFKTGDTVVF-KDGQYWIRGRTSVDIIKTGGYKVSAL 487
            + R  +   E  ++ +     G++ TGD     +DG YWI GR   D++   G+ +S  
Sbjct: 524 GIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRID-DMLNVSGHLLSTA 582

Query: 488 EVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHR---ELKEWARNVLAPY 544
           EVE  L+ H ++ + AV+G P    G+ +   VTL +GH+ S +   ELK+  R  + P 
Sbjct: 583 EVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPI 642

Query: 545 AVPSELVLVEEIPRNQMGKIDKKAL 569
           A P  +     +P+ + GKI ++ L
Sbjct: 643 ATPDYIQNAPGLPKTRSGKIMRRVL 667


>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
           sapiens]
          Length = 689

 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 135/551 (24%), Positives = 224/551 (40%), Gaps = 88/551 (15%)

Query: 65  RHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVP 124
           R TYREL   + RL+  + R      G  R +RV+         V A  A    G V   
Sbjct: 140 RITYRELLETTCRLANTLKR-----HGVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTV 194

Query: 125 LYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPV-VRKLGVPLLPLTPAI--------- 174
           ++    A  L   I D++  VV+   + L     V ++K+    +   P +         
Sbjct: 195 IFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRT 254

Query: 175 ----YTGAVEEPAE--------VPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAV 222
               + G ++ P E        V  PE         ++YTSG+TG PKG++ T      +
Sbjct: 255 DNKVHMGDLDVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGY-LL 313

Query: 223 VTGLVHKWAWTKD--DVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQ-----QV 275
              L HK  +     D+   V  +  + G    +  PL  GAT V+  E +P      + 
Sbjct: 314 YAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLF-ESTPVYPNAGRY 372

Query: 276 WEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAAL 335
           WE   + E  +IN F   PT    L++Y D  + + + +  LR +          GS   
Sbjct: 373 WE---TVERLKINQFYGAPTAVRLLLKYGDA-WVKKYDRSSLRTL----------GSVGE 418

Query: 336 PLPVLEKWK---NITGH---TLLERYGMTEIGMALSGPLTT---AVRLPGSVGTPLPGVQ 386
           P+   E W+    + G    TL++ +  TE G     P  +   A  LP     P  G+ 
Sbjct: 419 PINC-EAWEWLHRVVGDSRCTLVDTWWQTETGGICIAPRPSEEGAEILPAMAMRPFFGIV 477

Query: 387 VRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRG--PSVFREYWNKPEETK 444
             ++                 DE+G+ V        G L +    P + R  +   +   
Sbjct: 478 PVLM-----------------DEKGSVVEGS--NVSGALCISQAWPGMARTIYGDHQRFV 518

Query: 445 SAF--TLDGWFKTGDTVVFKDGQYW-IRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITD 501
            A+     G++ TGD     +G Y+ I GR   D+I   G+++   E+E  +  HP++ +
Sbjct: 519 DAYFKAYPGYYFTGDGAYRTEGGYYQITGRMD-DVINISGHRLGTAEIEDAIADHPAVPE 577

Query: 502 VAVIGVPDMTWGQRVTAVVTLREGHSLSH---RELKEWARNVLAPYAVPSELVLVEEIPR 558
            AVIG P    G+   A + +++    S    +ELK      +A YAVP E+++V+ +P+
Sbjct: 578 SAVIGYPHDIKGEAAFAFIVVKDSAGDSDVVVQELKSMVATKIAKYAVPDEILVVKRLPK 637

Query: 559 NQMGKIDKKAL 569
            + GK+ ++ L
Sbjct: 638 TRSGKVMRRLL 648


>gi|57165410 acyl-CoA synthetase long-chain family member 6 isoform
           a [Homo sapiens]
          Length = 722

 Score = 89.7 bits (221), Expect = 6e-18
 Identities = 111/444 (25%), Positives = 173/444 (38%), Gaps = 104/444 (23%)

Query: 78  LSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPAAQLEYV 137
           L Q  C+ C        ++ +     N   +++ + A +    V VPLY       + Y+
Sbjct: 162 LLQHNCKAC-------TDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYI 214

Query: 138 ICDSQSSVVLAS--QEYLELLSPVVRKL--GVPLL----PLTPAIYT-----GAV----- 179
           I  +  S V+    Q+ + LL  V RK   G+ L+    P   A+       G V     
Sbjct: 215 INTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQ 274

Query: 180 ------EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVH----K 229
                 +E  + PVP Q   +  +++ +TSGTTG PKG + TH N+ A  +G +     +
Sbjct: 275 AVEDCGQENHQAPVPPQP--DDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQ 332

Query: 230 WAWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRI-- 287
           WA T  DV +  LPL H+   +   +     G       +        + LS +   +  
Sbjct: 333 WAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDI-------RLLSDDMKALCP 385

Query: 288 NVFMAVPTIYTKLMEYYDRHFTQ---PHAQDFLRAVCEEK-------------------- 324
            +F  VP +  ++   YD+ F+Q   P  +  L    + K                    
Sbjct: 386 TIFPVVPRLLNRM---YDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFF 442

Query: 325 ----------IRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVRL 374
                     +R++V+G+A     VL   +   G  + E YG TE     +   T     
Sbjct: 443 NKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFT-TPGDWT 501

Query: 375 PGSVGTPLPGVQVRIVS-ENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVF 433
            G VG PLP   +++V  E     AC                    + EGE+ VRGP+VF
Sbjct: 502 SGHVGAPLPCNHIKLVDVEELNYWAC--------------------KGEGEICVRGPNVF 541

Query: 434 REYWNKPEETKSAFTLDGWFKTGD 457
           + Y   P+ TK A   DGW  TGD
Sbjct: 542 KGYLKDPDRTKEALDSDGWLHTGD 565


>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
           b [Homo sapiens]
          Length = 683

 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 111/423 (26%), Positives = 176/423 (41%), Gaps = 89/423 (21%)

Query: 95  EERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA---------AQLEYVICDS-QSS 144
           ++ V     N   +++++ A +    VAVPLY              A +  VICD+ Q +
Sbjct: 132 DQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKA 191

Query: 145 VVLA---------SQEYLELLSPVV-------RKLGVPLLPLTPAIYTGAVEEPAEVPVP 188
           +VL          S + + L+ P          K G+ +L L  A   G  +E    PVP
Sbjct: 192 LVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLG--KEHFRKPVP 249

Query: 189 EQGWRNKGAMIIYTSGTTGRPKGVLSTHQNI----RAVVTGLVHKWAWTKDDVILHVLPL 244
                   ++I +TSGTTG PKG + THQNI     A +  + H +  T DDV +  LPL
Sbjct: 250 PSP--EDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPL 307

Query: 245 HHV-HGVVNALL--CPLWVG-----------ATCVMMPEFSP------QQVWEKFLSSET 284
            H+   +V A++  C   VG               + P   P       ++++K  +   
Sbjct: 308 AHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAK 367

Query: 285 PRINVF---MAVPTIYTKLMEYYDRH--FTQPHAQDFLRAVCEEKIRLMVSGSAALPLPV 339
             +  F   +AV + + +L +   RH  F        ++     ++R++V+G+A +   V
Sbjct: 368 TPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSV 427

Query: 340 LEKWKNITGHTLLERYGMTE----IGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQ 395
           +  ++   G  + E YG TE        L G  T+     G VG PL             
Sbjct: 428 MTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTS-----GHVGVPL------------- 469

Query: 396 REACSYT-IHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWFK 454
             AC+Y  +    D     V       EGE+ ++G +VF+ Y   PE+T+ A   DGW  
Sbjct: 470 --ACNYVKLEDVADMNYFTV-----NNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLH 522

Query: 455 TGD 457
           TGD
Sbjct: 523 TGD 525


>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
           b [Homo sapiens]
          Length = 683

 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 111/423 (26%), Positives = 176/423 (41%), Gaps = 89/423 (21%)

Query: 95  EERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA---------AQLEYVICDS-QSS 144
           ++ V     N   +++++ A +    VAVPLY              A +  VICD+ Q +
Sbjct: 132 DQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKA 191

Query: 145 VVLA---------SQEYLELLSPVV-------RKLGVPLLPLTPAIYTGAVEEPAEVPVP 188
           +VL          S + + L+ P          K G+ +L L  A   G  +E    PVP
Sbjct: 192 LVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLG--KEHFRKPVP 249

Query: 189 EQGWRNKGAMIIYTSGTTGRPKGVLSTHQNI----RAVVTGLVHKWAWTKDDVILHVLPL 244
                   ++I +TSGTTG PKG + THQNI     A +  + H +  T DDV +  LPL
Sbjct: 250 PSP--EDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPL 307

Query: 245 HHV-HGVVNALL--CPLWVG-----------ATCVMMPEFSP------QQVWEKFLSSET 284
            H+   +V A++  C   VG               + P   P       ++++K  +   
Sbjct: 308 AHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAK 367

Query: 285 PRINVF---MAVPTIYTKLMEYYDRH--FTQPHAQDFLRAVCEEKIRLMVSGSAALPLPV 339
             +  F   +AV + + +L +   RH  F        ++     ++R++V+G+A +   V
Sbjct: 368 TPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSV 427

Query: 340 LEKWKNITGHTLLERYGMTE----IGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQ 395
           +  ++   G  + E YG TE        L G  T+     G VG PL             
Sbjct: 428 MTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTS-----GHVGVPL------------- 469

Query: 396 REACSYT-IHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWFK 454
             AC+Y  +    D     V       EGE+ ++G +VF+ Y   PE+T+ A   DGW  
Sbjct: 470 --ACNYVKLEDVADMNYFTV-----NNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLH 522

Query: 455 TGD 457
           TGD
Sbjct: 523 TGD 525


>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
           a [Homo sapiens]
          Length = 739

 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 111/423 (26%), Positives = 176/423 (41%), Gaps = 89/423 (21%)

Query: 95  EERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA---------AQLEYVICDS-QSS 144
           ++ V     N   +++++ A +    VAVPLY              A +  VICD+ Q +
Sbjct: 188 DQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKA 247

Query: 145 VVLA---------SQEYLELLSPVV-------RKLGVPLLPLTPAIYTGAVEEPAEVPVP 188
           +VL          S + + L+ P          K G+ +L L  A   G  +E    PVP
Sbjct: 248 LVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLG--KEHFRKPVP 305

Query: 189 EQGWRNKGAMIIYTSGTTGRPKGVLSTHQNI----RAVVTGLVHKWAWTKDDVILHVLPL 244
                   ++I +TSGTTG PKG + THQNI     A +  + H +  T DDV +  LPL
Sbjct: 306 PSP--EDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPL 363

Query: 245 HHV-HGVVNALL--CPLWVG-----------ATCVMMPEFSP------QQVWEKFLSSET 284
            H+   +V A++  C   VG               + P   P       ++++K  +   
Sbjct: 364 AHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAK 423

Query: 285 PRINVF---MAVPTIYTKLMEYYDRH--FTQPHAQDFLRAVCEEKIRLMVSGSAALPLPV 339
             +  F   +AV + + +L +   RH  F        ++     ++R++V+G+A +   V
Sbjct: 424 TPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSV 483

Query: 340 LEKWKNITGHTLLERYGMTE----IGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQ 395
           +  ++   G  + E YG TE        L G  T+     G VG PL             
Sbjct: 484 MTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTS-----GHVGVPL------------- 525

Query: 396 REACSYT-IHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWFK 454
             AC+Y  +    D     V       EGE+ ++G +VF+ Y   PE+T+ A   DGW  
Sbjct: 526 --ACNYVKLEDVADMNYFTV-----NNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLH 578

Query: 455 TGD 457
           TGD
Sbjct: 579 TGD 581


>gi|57165412 acyl-CoA synthetase long-chain family member 6 isoform
           b [Homo sapiens]
          Length = 722

 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 110/444 (24%), Positives = 172/444 (38%), Gaps = 104/444 (23%)

Query: 78  LSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPAAQLEYV 137
           L Q  C+ C        ++ +     N   +++ + A +    V VPLY       + Y+
Sbjct: 162 LLQHNCKAC-------TDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYI 214

Query: 138 ICDSQSSVVLAS--QEYLELLSPVVRKL--GVPLL----PLTPAIYT-----GAV----- 179
           I  +  S V+    Q+ + LL  V RK   G+ L+    P   A+       G V     
Sbjct: 215 INTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQ 274

Query: 180 ------EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWT 233
                 +E  + PVP Q   +  +++ +TSGTTG PKG + TH N+ A  +G +      
Sbjct: 275 AVEDCGQENHQAPVPPQP--DDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTEKV 332

Query: 234 ----KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRI-- 287
               +DDV++  LPL H+   V   +     G       +        + LS +   +  
Sbjct: 333 IFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDI-------RLLSDDMKALCP 385

Query: 288 NVFMAVPTIYTKLMEYYDRHFTQ---PHAQDFLRAVCEEK-------------------- 324
            +F  VP +  ++   YD+ F+Q   P  +  L    + K                    
Sbjct: 386 TIFPVVPRLLNRM---YDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFF 442

Query: 325 ----------IRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVRL 374
                     +R++V+G+A     VL   +   G  + E YG TE     +   T     
Sbjct: 443 NKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFT-TPGDWT 501

Query: 375 PGSVGTPLPGVQVRIVS-ENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVF 433
            G VG PLP   +++V  E     AC                    + EGE+ VRGP+VF
Sbjct: 502 SGHVGAPLPCNHIKLVDVEELNYWAC--------------------KGEGEICVRGPNVF 541

Query: 434 REYWNKPEETKSAFTLDGWFKTGD 457
           + Y   P+ TK A   DGW  TGD
Sbjct: 542 KGYLKDPDRTKEALDSDGWLHTGD 565


>gi|13325057 solute carrier family 27 (fatty acid transporter),
           member 5 [Homo sapiens]
          Length = 690

 Score = 86.7 bits (213), Expect = 5e-17
 Identities = 137/542 (25%), Positives = 215/542 (39%), Gaps = 66/542 (12%)

Query: 64  GRHTYRELYSRSLRLSQEICRLCG-----CVGGDLREERVSFLCANDASYVVAQWASWMS 118
           G  T+ EL +R+ + +  +    G     C G    E     + A+ A   +  W     
Sbjct: 141 GSVTFGELDARACQAAWALKAELGDPASLCAG----EPTALLVLASQAVPALCMWLGLAK 196

Query: 119 GGVAVPLYRKHPAAQ-LEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPL------- 170
            G        H     L + +  S + V++   +  E L  ++ KL    +         
Sbjct: 197 LGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTS 256

Query: 171 -TPAIYT--GAVEEPAEVPVPEQ-----GWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAV 222
            TP +     A++     PVP        WR+  A+ IYTSGTTG PK  + TH+ +  +
Sbjct: 257 PTPGVGALGAALDAAPSHPVPADLRAGITWRSP-ALFIYTSGTTGLPKPAILTHERVLQM 315

Query: 223 VTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSS 282
              L    A T DDV+  VLPL+HV G+V  +L  L +GATCV+ P+FS    W+     
Sbjct: 316 SKMLSLSGA-TADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWD---DC 371

Query: 283 ETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEK 342
               + V + V     +L+ Y      QP  +          +RL +     L   V E 
Sbjct: 372 RQHGVTVILYV----GELLRYLCNIPQQPEDR-------THTVRLAMGN--GLRADVWET 418

Query: 343 WKNITGH-TLLERYGMTEIGMAL---------SGPLTTAVRLPGSVGTPLPGVQVRIVSE 392
           ++   G   + E YG TE  M L          G ++  +R+     +P   VQ  + + 
Sbjct: 419 FQQRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRML----SPFELVQFDMEAA 474

Query: 393 NPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGW 452
            P R+   + I     E G  +T     ++  +  RGP   RE   +        + D +
Sbjct: 475 EPVRDNQGFCIPVGLGEPGLLLTK-VVSQQPFVGYRGP---RELSERKLVRNVRQSGDVY 530

Query: 453 FKTGDTVVF-KDGQYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIG--VPD 509
           + TGD +   ++G  + R R   D  +  G  VS  EVE  L     +  V V G  VP 
Sbjct: 531 YNTGDVLAMDREGFLYFRDRLG-DTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPG 589

Query: 510 MTWGQRVTAVVTLREGHSLSHRELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
              G+   A V L  G +    +L +  R  L  YA P  + + + +      K+ K  L
Sbjct: 590 CE-GKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRL 648

Query: 570 IR 571
           +R
Sbjct: 649 VR 650


>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
          Length = 730

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 122/466 (26%), Positives = 183/466 (39%), Gaps = 69/466 (14%)

Query: 146 VLASQEYLELLSP---VVRKLGVPLLPLTPAIYTGAV-----EEPAEVPVPEQGWRNKGA 197
           ++ + E+LE L P    +R +G+ L    P  +   +     E  AEV  P  G+ +   
Sbjct: 265 LVLAPEFLESLEPDLPALRAMGLHLWAAGPGTHPAGISDLLAEVSAEVDGPVPGYLSSPQ 324

Query: 198 MI------IYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVV 251
            I      I+TSGTTG PK    +H  I     G        ++DVI   LPL+H+ G +
Sbjct: 325 SITDTCLYIFTSGTTGLPKAARISHLKILQC-QGFYQLCGVHQEDVIYLALPLYHMSGSL 383

Query: 252 NALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQP 311
             ++  + +GAT V+  +FS  Q WE     +  R+ VF  +  +   L+        QP
Sbjct: 384 LGIVGCMGIGATVVLKSKFSAGQFWE---DCQQHRVTVFQYIGELCRYLV-------NQP 433

Query: 312 HAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGH----TLLERYGMTEIGMALSGP 367
            +    +A    K+RL V GS   P    + W+          +LE YG+TE  +A    
Sbjct: 434 PS----KAERGHKVRLAV-GSGLRP----DTWERFVRRFGPLQVLETYGLTEGNVATIN- 483

Query: 368 LTTAVRLPGSVGT---------PLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGF 418
             T  R  G+VG          P   ++  + +  P R+   + +     E G  V P  
Sbjct: 484 -YTGQR--GAVGRASWLYKHIFPFSLIRYDVTTGEPIRDPQGHCMATSPGEPGLLVAP-- 538

Query: 419 EEKEGELLVRGPSVFREYWNKPEETKSAFTL------DGWFKTGDTVVFKDGQYWIRGRT 472
                   V   S F  Y   PE  +           D +F TGD +V  D  +      
Sbjct: 539 --------VSQQSPFLGYAGGPELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDR 590

Query: 473 SVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVP-DMTWGQRVTAVVTLREGHSLSHR 531
           + D  +  G  V+  EV     A   + +V V GV      G+   A + LR  H+L   
Sbjct: 591 TGDTFRWKGENVATTEVAEVFEALDFLQEVNVYGVTVPGHEGRAGMAALVLRPPHALDLM 650

Query: 532 ELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKALIRH-FHPS 576
           +L       L PYA P  L L E +   +  K  K  +    F PS
Sbjct: 651 QLYTHVSENLPPYARPRFLRLQESLATTETFKQQKVRMANEGFDPS 696


>gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo
           sapiens]
          Length = 698

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 110/452 (24%), Positives = 178/452 (39%), Gaps = 109/452 (24%)

Query: 80  QEICRLCGCVGGDL--------REERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA 131
           +++  L  C+G  L         ++ +     N   +V+ +   +    V VPLY     
Sbjct: 124 KQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGN 183

Query: 132 AQLEYVICDSQSSVVLAS--QEYLELLSPVVRKL--GVPLLPLTPAIYTGAVEEPAEVPV 187
             + Y++  ++ S+V     ++   LL  V  KL  G+ ++ +  A  +  VE      V
Sbjct: 184 EAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGV 243

Query: 188 P--------EQGWRNKG----------AMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHK 229
                    + G  N+           A+I +TSGTTG PKG + TH+NI +  +  V  
Sbjct: 244 EVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKA 303

Query: 230 WAWT----KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWE---KFLSS 282
              T     DD ++  LPL H+   V            CVM+   +    ++   + L  
Sbjct: 304 TENTVNPCPDDTLISFLPLAHMFERV----------VECVMLCHGAKIGFFQGDIRLLMD 353

Query: 283 ETPRIN--VFMAVPTIYTKLMEYYDRHFTQPHAQ------DF------------------ 316
           +   +   VF  VP +  ++   +DR F Q +        DF                  
Sbjct: 354 DLKVLQPTVFPVVPRLLNRM---FDRIFGQANTTLKRWLLDFASKRKEAELRSGIIRNNS 410

Query: 317 ---------LRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEI--GMALS 365
                    +++    ++RLMV+G+A +   VL   +   G    E YG TE   G  L+
Sbjct: 411 LWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLT 470

Query: 366 GPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGEL 425
            P        G VG P+P   +++V      E  +Y + AEG              EGE+
Sbjct: 471 MPGDWTA---GHVGAPMPCNLIKLVDV----EEMNY-MAAEG--------------EGEV 508

Query: 426 LVRGPSVFREYWNKPEETKSAFTLDGWFKTGD 457
            V+GP+VF+ Y   P +T  A   DGW  TGD
Sbjct: 509 CVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540


>gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]
          Length = 666

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 108/482 (22%), Positives = 188/482 (39%), Gaps = 59/482 (12%)

Query: 53  FGDRIALVDQHGRH----TYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASY 108
           FG   AL  ++G+      + + Y    + ++ + +L     G  R   V  L  N A +
Sbjct: 64  FGTYPALASKNGKKWEILNFNQYYEACRKAAKSLIKL-----GLERFHGVGILGFNSAEW 118

Query: 109 VVAQWASWMSGGVAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLL 168
            +    + ++GG+ V +Y  + A   +YVI  ++ +++L   +  + L  ++      L 
Sbjct: 119 FITAVGAILAGGLCVGIYATNSAEVCQYVITHAKVNILLVEND--QQLQKILSIPQSSLE 176

Query: 169 PLTPAI--------------YTGAVEEPAEVP------VPEQGWRNKGAMIIYTSGTTGR 208
           PL   I              +   +E    +P      V E    N+ A++IYTSGTTG 
Sbjct: 177 PLKAIIQYRLPMKKNNNLYSWDDFMELGRSIPDTQLEQVIESQKANQCAVLIYTSGTTGI 236

Query: 209 PKGVLSTHQNIRAVVTGLVHKWAWT-KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMM 267
           PKGV+ +H NI  +   +   +  T K + ++  LPL H+   +  +  P+ +GA     
Sbjct: 237 PKGVMLSHDNITWIAGAVTKDFKLTDKHETVVSYLPLSHIAAQMMDIWVPIKIGALTYFA 296

Query: 268 PEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRL 327
              + +      L    P   VF+ VP I+ K+ E   ++  +         V    I  
Sbjct: 297 QADALKGTLVSTLKEVKP--TVFIGVPQIWEKIHEMVKKNSAKSMGLKKKAFVWARNIGF 354

Query: 328 MVSGSAAL---PLPVLEKW-KNITGHTLLERYGMTEIGMALSG--PLT-TAVRLPGSVGT 380
            V+    L     PV  +  K +    +    G+      +SG  PL         S+  
Sbjct: 355 KVNSKKMLGKYNTPVSYRMAKTLVFSKVKTSLGLDHCHSFISGTAPLNQETAEFFLSLDI 414

Query: 381 PLPGVQVRIVSENPQREACSYTIHAEGDER---GTKVTPG-----FEEKE---GELLVRG 429
           P+  +     S  P      +TI  + + R     K+  G     F++ +   GE+ + G
Sbjct: 415 PIGELYGLSESSGP------HTISNQNNYRLLSCGKILTGCKNMLFQQNKDGIGEICLWG 468

Query: 430 PSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKD-GQYWIRGRTSVDIIKTGGYKVSALE 488
             +F  Y     ET  A   +GW  +GD       G  ++ G     +I  GG  V  + 
Sbjct: 469 RHIFMGYLESETETTEAIDDEGWLHSGDLGQLDGLGFLYVTGHIKEILITAGGENVPPIP 528

Query: 489 VE 490
           VE
Sbjct: 529 VE 530


>gi|27477105 lipidosin [Homo sapiens]
          Length = 724

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 120/511 (23%), Positives = 204/511 (39%), Gaps = 82/511 (16%)

Query: 53  FGDRIAL----VDQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASY 108
           +GD IAL     D+    +Y + Y  + R ++   +L     G  +   V+ L  N   +
Sbjct: 116 YGDLIALGFKRQDKWEHISYSQYYLLARRAAKGFLKL-----GLKQAHSVAILGFNSPEW 170

Query: 109 VVAQWASWMSGGVAVPLYRKHPAAQLEYVICDSQSSVVLA-SQEYLELLSPVVRKL---- 163
             +   +  +GG+   +Y        +Y+  D  ++V++  +Q+ LE +  + ++L    
Sbjct: 171 FFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLPHLK 230

Query: 164 GVPLLPLTPA-----IYTGAVEEPAEV--PVPEQGWR--------NKGAMIIYTSGTTGR 208
            V +    P      +YT  +EE  E+   VPE+           N+  +++YTSGTTG 
Sbjct: 231 AVVIYKEPPPNKMANVYT--MEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTGN 288

Query: 209 PKGVLSTHQNIRAVV-----TGLVHKWAWTKDDVILHVLPLHHVHGVVNALLCPL-WVGA 262
           PKGV+ +  NI          G +   A  + +V++  LPL H+   +  L   + W   
Sbjct: 289 PKGVMLSQDNITWTARYGSQAGDIRP-AEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQ 347

Query: 263 TCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDFLR---- 318
            C   P+     +       E       M VP ++ K+ME       Q     F+R    
Sbjct: 348 VCFAEPDALKGSLVNTLREVEP---TSHMGVPRVWEKIMERIQEVAAQ---SGFIRRKML 401

Query: 319 ----AVCEEKIRLMVSGSAALPLP-------VLEKWKNITGHTLLER--YGMTEIGMALS 365
               +V  E+  L   GS   P         VL K +   G    ++  YG   + MA +
Sbjct: 402 LWAMSVTLEQ-NLTCPGSDLKPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPM-MAET 459

Query: 366 GPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFE------ 419
                 + +    G  L          +P     +Y +++ G     K+ PG        
Sbjct: 460 QHFFLGLNIRLYAGYGLSETSGPHFMSSPY----NYRLYSSG-----KLVPGCRVKLVNQ 510

Query: 420 --EKEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDT-VVFKDGQYWIRGRTSVDI 476
             E  GE+ + G ++F  Y N  ++T  A   +GW  TGD   +  DG  +I GR    I
Sbjct: 511 DAEGIGEICLWGRTIFMGYLNMEDKTCEAIDEEGWLHTGDAGRLDADGFLYITGRLKELI 570

Query: 477 IKTGGYKVSALEVEWHL-LAHPSITDVAVIG 506
           I  GG  V  + +E  + +  P I++  +IG
Sbjct: 571 ITAGGENVPPVPIEEAVKMELPIISNAMLIG 601


>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
          Length = 646

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 101/393 (25%), Positives = 155/393 (39%), Gaps = 29/393 (7%)

Query: 187 VPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILHVLPLHH 246
           +P +G  ++    IYTSGTTG PK  +  H     +     H +     DV+   LPL+H
Sbjct: 235 IPSKGMDDR-LFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYH 293

Query: 247 VHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDR 306
             G +  +   L  G T V+  +FS  + W+  +        V   +  I   L++   R
Sbjct: 294 SAGNIIGVGQCLIYGLTVVLRKKFSASRFWDDCIKY---NCTVVQYIGEICRYLLKQPVR 350

Query: 307 HFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSG 366
              + H           ++RL V G+   P    E  +      + E YG TE   +++ 
Sbjct: 351 EAERRH-----------RVRLAV-GNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIAN 398

Query: 367 PLTTAVRLPGSVGTPLPGV-QVRIVSENPQ-----REACSYTIHAEGDERGTKVTPGFEE 420
            +   V   G     LP V  +R+V  N       R+A    I  +  E G  V    + 
Sbjct: 399 -MDGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVG---QI 454

Query: 421 KEGELLVRGPSVFREYWNKPEETKSAFTL-DGWFKTGDTVVFKDGQYWIRGRTSVDIIKT 479
            + + L R      E     +   S F+  D  + +GD +V  +  Y      S D  + 
Sbjct: 455 NQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRW 514

Query: 480 GGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHS-LSHRELKEWAR 538
            G  VS  EVE  L      TDVAV GV  +   +    +  + + HS L    + +  +
Sbjct: 515 RGENVSTTEVEGVLSRLLGQTDVAVYGVA-VPGVEGKAGMAAVADPHSLLDPNAIYQELQ 573

Query: 539 NVLAPYAVPSELVLVEEIPRNQMGKIDKKALIR 571
            VLAPYA P  L L+ ++      KI K  L R
Sbjct: 574 KVLAPYARPIFLRLLPQVDTTGTFKIQKTRLQR 606


>gi|227499619 solute carrier family 27 (fatty acid transporter),
           member 2 isoform 1 [Homo sapiens]
          Length = 620

 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 131/546 (23%), Positives = 219/546 (40%), Gaps = 75/546 (13%)

Query: 67  TYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLY 126
           TY ++  RS ++++ +    G   GD     V+ L  N+ +YV   W   +  G A+   
Sbjct: 80  TYAQVDRRSNQVARALHDHLGLRQGDC----VALLMGNEPAYVWL-WLGLVKLGCAMACL 134

Query: 127 RKHPAAQ-LEYVICDSQSSVVLASQEY---LELLSPVVRKLGVPLLPLTPAIYTGA---- 178
             +  A+ L +      + V+L S E    +E + P ++K  V +  ++    T      
Sbjct: 135 NYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSF 194

Query: 179 ---VEEPAEVPVPEQGWRNK-----GAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW 230
              V+E +  P+PE  WR++      A+ IYTSGTTG PK  + THQ I    TGL    
Sbjct: 195 LDKVDEVSTEPIPES-WRSEVTFSTPALYIYTSGTTGLPKAAMITHQRI-WYGTGLTFVS 252

Query: 231 AWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVF 290
               DDVI   LP +H   ++  +   +  GAT  +  +FS  Q W+     +  + NV 
Sbjct: 253 GLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWD-----DCRKYNV- 306

Query: 291 MAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKW-KNITGH 349
             V     +L+ Y      +P+ +D        K+RL +     L   V  ++ K     
Sbjct: 307 -TVIQYIGELLRYLCNSPQKPNDRD-------HKVRLALGN--GLRGDVWRQFVKRFGDI 356

Query: 350 TLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVS----------ENPQREAC 399
            + E Y  TE  +          R  G+VG  +  +Q +I++          + P R+  
Sbjct: 357 CIYEFYAATEGNIG----FMNYARKVGAVGR-VNYLQKKIITYDLIKYDVEKDEPVRDEN 411

Query: 400 SYTIHAEGDERG------TKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWF 453
            Y +     E G      T++TP F    G          R+ + K          D +F
Sbjct: 412 GYCVRVPKGEVGLLVCKITQLTP-FNGYAGAKAQTEKKKLRDVFKKG---------DLYF 461

Query: 454 KTGDTVVFKDGQYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIG--VPDMT 511
            +GD ++     +        D  +  G  V+  EV   +     + +V V G  VPD  
Sbjct: 462 NSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHE 521

Query: 512 WGQRVTAVVTLREGHSLSHRELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKALIR 571
            G+   A + ++E H    ++L +   + L  YA P  L + + I      K  K  L+ 
Sbjct: 522 -GRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVE 580

Query: 572 H-FHPS 576
             F+P+
Sbjct: 581 EGFNPA 586


>gi|13375727 acyl-CoA synthetase short-chain family member 3 [Homo
           sapiens]
          Length = 686

 Score = 69.7 bits (169), Expect = 7e-12
 Identities = 94/407 (23%), Positives = 160/407 (39%), Gaps = 83/407 (20%)

Query: 199 IIYTSGTTGRPKGVLST--------HQNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGV 250
           I+YTSGTTG PKGV+          H ++ ++      +  W   D+   V   +  +G 
Sbjct: 296 ILYTSGTTGLPKGVIRPTGGYAVMLHWSMSSIYGLQPGEVWWAASDLGWVVGHSYICYG- 354

Query: 251 VNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEY-YDRHFT 309
                 PL  G T V+  E  P           TP    +  V      L E+     FT
Sbjct: 355 ------PLLHGNTTVLY-EGKPVG---------TPDAGAYFRV------LAEHGVAALFT 392

Query: 310 QPHAQDFLRAVCEE-------------KIRLMVSGSAALPLPVLEKWKNITGHTLLERYG 356
            P A   +RA+ ++             + + +        +  LE  KN+    +L+ + 
Sbjct: 393 APTA---IRAIRQQDPGAALGKQYSLTRFKTLFVAGERCDVETLEWSKNVFRVPVLDHWW 449

Query: 357 MTEIGMALS----GPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGT 412
            TE G  ++    G   +    PG  G  +PG  V I+ +N Q+                
Sbjct: 450 QTETGSPITASCVGLGNSKTPPPGQAGKSVPGYNVMILDDNMQKLKARCL---------- 499

Query: 413 KVTPGFEEKEGELLVR---GPSVFREYWNKPEETKSAF--TLDGWFKTGDT-VVFKDGQY 466
                     G ++V+    P  F   W   E  K  +     G++ T D   + ++G  
Sbjct: 500 ----------GNIVVKLPLPPGAFSGLWKNQEAFKHLYFEKFPGYYDTMDAGYMDEEGYL 549

Query: 467 WIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGH 526
           ++  R   D+I   G+++SA  +E  +L+H ++ D AV+G  D   G    A+  LR+  
Sbjct: 550 YVMSRVD-DVINVAGHRISAGAIEESILSHGTVADCAVVGKEDPLKGHVPLALCVLRKDI 608

Query: 527 SLSH----RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
           + +      E+ +  R  + P A     V V+++P+ + GKI + AL
Sbjct: 609 NATEEQVLEEIVKHVRQNIGPVAAFRNAVFVKQLPKTRSGKIPRSAL 655


>gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens]
          Length = 1098

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 101/389 (25%), Positives = 156/389 (40%), Gaps = 64/389 (16%)

Query: 197 AMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLC 256
           A +++TSGTTG PK V   H+ I   +      +  T++DV+    PL     VV   L 
Sbjct: 193 AYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEIFLA 252

Query: 257 PLWVGATCVMMP---EFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHA 313
            L  GA+ +++P   +  P ++     S    R+ V  A PT+         R  +Q   
Sbjct: 253 -LSSGASLLIVPTSVKLLPSKLASVLFSHH--RVTVLQATPTLLR-------RFGSQLIK 302

Query: 314 QDFLRAVCEEKIRLMVSGSAALP-LPVLEKWKNITGHT-LLERYGMTEIGM--------- 362
              L A     +R++  G  A P L VL  W+     T +   YG+TE+           
Sbjct: 303 STVLSATTS--LRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPE 360

Query: 363 -ALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEK 421
             L+   T    LP  +G PL G  V +      R+   +TI               +E 
Sbjct: 361 KTLNS--TLKCELPVQLGFPLLGTVVEV------RDTNGFTI---------------QEG 397

Query: 422 EGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTGG 481
            G++ + G +  R  +   E T    T+     TGD V  KDG+ +  GR    I + G 
Sbjct: 398 SGQVFLGGRN--RVCFLDDEVTVPLGTMRA---TGDFVTVKDGEIFFLGRKDSQIKRHG- 451

Query: 482 YKVSALEVEWHLLAHPSITDVAVIGVPDMTW-GQRVTAVVTLREGHSLSHRELKEWARNV 540
                L +E   L      ++  +    +TW  Q    +  + +  S+     KE  +  
Sbjct: 452 ---KRLNIE---LVQQVAEELQQVESCAVTWYNQEKLILFMVSKDASVKEYIFKE-LQKY 504

Query: 541 LAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
           L  +AVP ELVL++ +P    GKID   L
Sbjct: 505 LPSHAVPDELVLIDSLPFTSHGKIDVSEL 533


>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
           sapiens]
          Length = 438

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 76/348 (21%), Positives = 140/348 (40%), Gaps = 41/348 (11%)

Query: 65  RHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVP 124
           R ++ EL S S + +  +   C    GD    RV  +      + +A  A   +G V +P
Sbjct: 94  RWSFEELGSLSRKFANILSEACSLQRGD----RVILILPRVPEWWLANVACLRTGTVLIP 149

Query: 125 LYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGA------ 178
              +     + Y +  S+++ ++ +    ++L+P V  +      L   +          
Sbjct: 150 GTTQLTQKDILYRLQSSKANCIITN----DVLAPAVDAVASKCENLHSKLIVSENSREGW 205

Query: 179 ------VEEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWA- 231
                 ++  ++     +   N+   I +TSGT+G PK    TH +    ++     W  
Sbjct: 206 GNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLD 265

Query: 232 WTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVM---MPEFSPQQVWEKFLSSETPRIN 288
            T  DV+ +           +++  P W+   CV    +P F P  + +    S+ P I 
Sbjct: 266 LTPSDVMWNTSDTGWAKSAWSSVFSP-WIQGACVFTHHLPRFEPTSILQTL--SKYP-IT 321

Query: 289 VFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITG 348
           VF + PT+Y  L+            Q+ + +   + ++  VS    +   V EKW+N TG
Sbjct: 322 VFCSAPTVYRMLV------------QNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG 369

Query: 349 HTLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQR 396
             + E YG TE  + + G        PGS+G P P   V++ +   +R
Sbjct: 370 LDIYEGYGQTET-VLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRR 416


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,702,522
Number of Sequences: 37866
Number of extensions: 1133647
Number of successful extensions: 2382
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2242
Number of HSP's gapped (non-prelim): 64
length of query: 576
length of database: 18,247,518
effective HSP length: 108
effective length of query: 468
effective length of database: 14,157,990
effective search space: 6625939320
effective search space used: 6625939320
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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