Guide to the Human Genome
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Search of human proteins with 11321577

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11321577 2'-5'-oligoadenylate synthetase-like isoform a
[Homo sapiens]
         (514 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11321577 2'-5'-oligoadenylate synthetase-like isoform a [Homo...  1047   0.0  
gi|38016930 2'-5'-oligoadenylate synthetase-like isoform b [Homo...   446   e-125
gi|45007007 2'-5'oligoadenylate synthetase 3 [Homo sapiens]           266   3e-71
gi|74229015 2',5'-oligoadenylate synthetase 1 isoform 3 [Homo sa...   240   2e-63
gi|74229013 2',5'-oligoadenylate synthetase 1 isoform 1 [Homo sa...   240   2e-63
gi|74229011 2',5'-oligoadenylate synthetase 1 isoform 2 [Homo sa...   240   2e-63
gi|74229017 2'-5'-oligoadenylate synthetase 2 isoform 2 [Homo sa...   228   8e-60
gi|74229019 2'-5'-oligoadenylate synthetase 2 isoform 1 [Homo sa...   228   8e-60
gi|67191208 ubiquitin C [Homo sapiens]                                 73   5e-13
gi|11024714 ubiquitin B precursor [Homo sapiens]                       71   3e-12
gi|208022622 ubiquitin and ribosomal protein S27a precursor [Hom...    51   3e-06
gi|4506713 ubiquitin and ribosomal protein S27a precursor [Homo ...    51   3e-06
gi|4507761 ubiquitin and ribosomal protein L40 precursor [Homo s...    51   3e-06
gi|77539055 ubiquitin and ribosomal protein L40 precursor [Homo ...    51   3e-06
gi|4826774 ISG15 ubiquitin-like modifier [Homo sapiens]                50   4e-06
gi|74229021 2'-5'-oligoadenylate synthetase 2 isoform 3 [Homo sa...    48   2e-05
gi|239757745 PREDICTED: similar to hCG1790904 [Homo sapiens]           48   2e-05
gi|239752254 PREDICTED: similar to hCG1790904 [Homo sapiens]           48   2e-05
gi|239746765 PREDICTED: similar to hCG1790904 [Homo sapiens]           48   2e-05
gi|222352096 ubiquitin D [Homo sapiens]                                43   6e-04
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]    36   0.073
gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]     36   0.073
gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]     36   0.073
gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]    36   0.073
gi|4506387 UV excision repair protein RAD23 homolog B [Homo sapi...    35   0.16 
gi|7657667 ubiquitin-like 4 [Homo sapiens]                             35   0.21 
gi|5453760 neural precursor cell expressed, developmentally down...    34   0.36 
gi|171906567 peripheral benzodiazepine receptor-associated prote...    32   1.4  
gi|171906559 peripheral benzodiazepine receptor-associated prote...    32   1.4  
gi|5454180 zinc finger protein 193 [Homo sapiens]                      31   2.4  

>gi|11321577 2'-5'-oligoadenylate synthetase-like isoform a [Homo
           sapiens]
          Length = 514

 Score = 1047 bits (2707), Expect = 0.0
 Identities = 514/514 (100%), Positives = 514/514 (100%)

Query: 1   MALMQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVR 60
           MALMQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVR
Sbjct: 1   MALMQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVR 60

Query: 61  VLKVVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLD 120
           VLKVVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLD
Sbjct: 61  VLKVVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLD 120

Query: 121 LGLEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKA 180
           LGLEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKA
Sbjct: 121 LGLEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKA 180

Query: 181 CGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALELLT 240
           CGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALELLT
Sbjct: 181 CGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALELLT 240

Query: 241 IYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKKER 300
           IYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKKER
Sbjct: 241 IYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKKER 300

Query: 301 PIILDPADPTLNVAEGYRWDIVAQRASQCLKQDCCYDNRENPISSWNVKRARDIHLTVEQ 360
           PIILDPADPTLNVAEGYRWDIVAQRASQCLKQDCCYDNRENPISSWNVKRARDIHLTVEQ
Sbjct: 301 PIILDPADPTLNVAEGYRWDIVAQRASQCLKQDCCYDNRENPISSWNVKRARDIHLTVEQ 360

Query: 361 RGYPDFNLIVNPYEPIRKVKEKIRRTRGYSGLQRLSFQVPGSERQLLSSRCSLAKYGIFS 420
           RGYPDFNLIVNPYEPIRKVKEKIRRTRGYSGLQRLSFQVPGSERQLLSSRCSLAKYGIFS
Sbjct: 361 RGYPDFNLIVNPYEPIRKVKEKIRRTRGYSGLQRLSFQVPGSERQLLSSRCSLAKYGIFS 420

Query: 421 HTHIYLLETIPSEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQG 480
           HTHIYLLETIPSEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQG
Sbjct: 421 HTHIYLLETIPSEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQG 480

Query: 481 QVLQDWLGLGIYGIQDSDTLILSKKKGEALFPAS 514
           QVLQDWLGLGIYGIQDSDTLILSKKKGEALFPAS
Sbjct: 481 QVLQDWLGLGIYGIQDSDTLILSKKKGEALFPAS 514


>gi|38016930 2'-5'-oligoadenylate synthetase-like isoform b [Homo
           sapiens]
          Length = 255

 Score =  446 bits (1148), Expect = e-125
 Identities = 219/219 (100%), Positives = 219/219 (100%)

Query: 1   MALMQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVR 60
           MALMQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVR
Sbjct: 1   MALMQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVR 60

Query: 61  VLKVVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLD 120
           VLKVVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLD
Sbjct: 61  VLKVVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLD 120

Query: 121 LGLEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKA 180
           LGLEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKA
Sbjct: 121 LGLEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKA 180

Query: 181 CGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQ 219
           CGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQ
Sbjct: 181 CGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQ 219


>gi|45007007 2'-5'oligoadenylate synthetase 3 [Homo sapiens]
          Length = 1087

 Score =  266 bits (680), Expect = 3e-71
 Identities = 142/348 (40%), Positives = 207/348 (59%), Gaps = 11/348 (3%)

Query: 7    LYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVVK 66
            LY TPA  LD F++++LQP+R++  +V  AV T+  FL++  F+     +  ++V+KVVK
Sbjct: 747  LYQTPAGDLDKFISEFLQPNRQFLAQVNKAVDTICSFLKENCFR-----NSPIKVIKVVK 801

Query: 67   VGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTM--WQSQDLLDLGLE 124
             GS   GT LR   + +LV FLSCF  F E      +++  I   +   Q +   ++  E
Sbjct: 802  GGSSAKGTALRGRSDADLVVFLSCFSQFTEQGNKRAEIISEIRAQLEACQQERQFEVKFE 861

Query: 125  DLRMEQRVPDALVFTIQTRGTAEP-ITVTIVPAYRALGPSLPNSQPPPEVYVSLIKACGG 183
              + E   P  L F++ ++   +  +   ++PA+ ALG  +  S+P  +VYV LI +   
Sbjct: 862  VSKWEN--PRVLSFSLTSQTMLDQSVDFDVLPAFDALGQLVSGSRPSSQVYVDLIHSYSN 919

Query: 184  PGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALELLTIYA 243
             G +   F+ELQR+F+  RPTKLKSL+RLVKHWYQQ  K    R +LPP + LELLT+YA
Sbjct: 920  AGEYSTCFTELQRDFIISRPTKLKSLIRLVKHWYQQCTKISKGRGSLPPQHGLELLTVYA 979

Query: 244  WEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKKERPII 303
            WE G  +D  F + EGF TV++L+ +Y  +CIYWT  Y   +  + D +++QL+K RPII
Sbjct: 980  WEQG-GKDSQFNMAEGFRTVLELVTQYRQLCIYWTINYNAKDKTVGDFLKQQLQKPRPII 1038

Query: 304  LDPADPTLNVAEGYRWDIVAQRASQCLKQDCCYDNRENPISSWNVKRA 351
            LDPADPT N+    RWD++A+ A+ C    CC      PI  W VK A
Sbjct: 1039 LDPADPTGNLGHNARWDLLAKEAAACTSALCCMGRNGIPIQPWPVKAA 1086



 Score =  239 bits (611), Expect = 3e-63
 Identities = 137/346 (39%), Positives = 201/346 (58%), Gaps = 12/346 (3%)

Query: 6   ELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVV 65
           +LYSTPA+ LD FVA+ LQP +E+ E+   A+  +   LR+   +G R      RVLK V
Sbjct: 2   DLYSTPAAALDRFVARRLQPRKEFVEKARRALGALAAALRE---RGGRLGAAAPRVLKTV 58

Query: 66  KVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVL---RLIWKTMWQSQDLLDLG 122
           K GS G GT L+   + ELV FL CF S+ +      ++L   R   ++ WQ+      G
Sbjct: 59  KGGSSGRGTALKGGCDSELVIFLDCFKSYVDQRARRAEILSEMRASLESWWQNPVP---G 115

Query: 123 LEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKACG 182
           L     EQ VP AL F + +    + + V++VPA+  LG +    +P P+VY +L+ +  
Sbjct: 116 LRLTFPEQSVPGALQFRLTSVDLEDWMDVSLVPAFNVLGQAGSGVKPKPQVYSTLLNSGC 175

Query: 183 GPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALELLTIY 242
             G     F+EL+RNFV  RP KLK+L+ LVKHWY Q       +  LPP+YALELLTI+
Sbjct: 176 QGGEHAACFTELRRNFVNIRPAKLKNLILLVKHWYHQVCLQGLWKETLPPVYALELLTIF 235

Query: 243 AWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKKERPI 302
           AWE G ++D  F L EG  TV+ L+ +++ +C++WT  Y   +  +   +++QLK+ RP+
Sbjct: 236 AWEQGCKKDA-FSLAEGLRTVLGLIQQHQHLCVFWTVNYGFEDPAVGQFLQRQLKRPRPV 294

Query: 303 ILDPADPTLNVAEG--YRWDIVAQRASQCLKQDCCYDNRENPISSW 346
           ILDPADPT ++  G  + WD++AQ A+ C    C      +P+ SW
Sbjct: 295 ILDPADPTWDLGNGAAWHWDLLAQEAASCYDHPCFLRGMGDPVQSW 340



 Score =  211 bits (537), Expect = 1e-54
 Identities = 126/353 (35%), Positives = 195/353 (55%), Gaps = 21/353 (5%)

Query: 6   ELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVV 65
           +L   P   LD F+   L+P  +++E+V  A+  +   L +             +  +V 
Sbjct: 407 DLSQIPTKELDRFIQDHLKPSPQFQEQVKKAIDIILRCLHENCVH---------KASRVS 457

Query: 66  KVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVL---RLIWKTMWQSQDLLDLG 122
           K GSFG GT LR   +VEL+ FL+CF  +++      ++L   R   ++ WQ Q +  L 
Sbjct: 458 KGGSFGRGTDLRDGCDVELIIFLNCFTDYKDQGPRRAEILDEMRAQLESWWQDQ-VPSLS 516

Query: 123 LEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKACG 182
           L+    EQ VP+AL F + +        V+++PA+ A+G     ++P P+VY  L+ +  
Sbjct: 517 LQF--PEQNVPEALQFQLVSTALKSWTDVSLLPAFDAVGQLSSGTKPNPQVYSRLLTSGC 574

Query: 183 GPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYV---KARSPR-ANLPPLYALEL 238
             G     F+EL+RNF+  RP KLK+L+ LVKHWY+Q     K + P  A+LPP YALEL
Sbjct: 575 QEGEHKACFAELRRNFMNIRPVKLKNLILLVKHWYRQVAAQNKGKGPAPASLPPAYALEL 634

Query: 239 LTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKK 298
           LTI+AWE G  +D  F + +GF TV+ L+ +++ +C+YWT  Y+  +  +   +  QL+K
Sbjct: 635 LTIFAWEQGCRQD-CFNMAQGFRTVLGLVQQHQQLCVYWTVNYSTEDPAMRMHLLGQLRK 693

Query: 299 ERPIILDPADPTLNVAEGYRWDIVAQRASQCLKQDCCYDNRENPISSWNVKRA 351
            RP++LDPADPT NV  G  W+++AQ A+    Q C        +  W+V  A
Sbjct: 694 PRPLVLDPADPTWNVGHG-SWELLAQEAAALGMQACFLSRDGTSVQPWDVMPA 745


>gi|74229015 2',5'-oligoadenylate synthetase 1 isoform 3 [Homo
           sapiens]
          Length = 414

 Score =  240 bits (613), Expect = 2e-63
 Identities = 141/350 (40%), Positives = 198/350 (56%), Gaps = 14/350 (4%)

Query: 4   MQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLK 63
           M +L +TPA  LD F+  +L P   ++ ++  A+  +  FL++  F   RG    V V K
Sbjct: 1   MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCF---RGSSYPVCVSK 57

Query: 64  VVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTM--WQSQDLLDL 121
           VVK GS G GT LR   + +LV FLS   +FQ+      + ++ I + +   Q +    +
Sbjct: 58  VVKGGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSV 117

Query: 122 GLEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKAC 181
             E        P AL F + +    E +   ++PA+ ALG      +P P++YV LI+ C
Sbjct: 118 KFEVQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEEC 177

Query: 182 GG---PGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALEL 238
                 G F   F+ELQR+F+K RPTKLKSL+RLVKHWYQ     +     LPP YALEL
Sbjct: 178 TDLQKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQN---CKKKLGKLPPQYALEL 234

Query: 239 LTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKK 298
           LT+YAWE G+ +  +F   +GF TV++L++ Y+ +CIYWTKYY   N IIE  +R+QL K
Sbjct: 235 LTVYAWERGSMKT-HFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTK 293

Query: 299 ERPIILDPADPTLNVAEG--YRWDIVAQRASQCLKQDCCYDNRENPISSW 346
            RP+ILDPADPT N+  G    W  +AQ A   L   C  +   +P+SSW
Sbjct: 294 PRPVILDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSW 343


>gi|74229013 2',5'-oligoadenylate synthetase 1 isoform 1 [Homo
           sapiens]
          Length = 400

 Score =  240 bits (613), Expect = 2e-63
 Identities = 141/350 (40%), Positives = 198/350 (56%), Gaps = 14/350 (4%)

Query: 4   MQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLK 63
           M +L +TPA  LD F+  +L P   ++ ++  A+  +  FL++  F   RG    V V K
Sbjct: 1   MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCF---RGSSYPVCVSK 57

Query: 64  VVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTM--WQSQDLLDL 121
           VVK GS G GT LR   + +LV FLS   +FQ+      + ++ I + +   Q +    +
Sbjct: 58  VVKGGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSV 117

Query: 122 GLEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKAC 181
             E        P AL F + +    E +   ++PA+ ALG      +P P++YV LI+ C
Sbjct: 118 KFEVQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEEC 177

Query: 182 GG---PGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALEL 238
                 G F   F+ELQR+F+K RPTKLKSL+RLVKHWYQ     +     LPP YALEL
Sbjct: 178 TDLQKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQN---CKKKLGKLPPQYALEL 234

Query: 239 LTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKK 298
           LT+YAWE G+ +  +F   +GF TV++L++ Y+ +CIYWTKYY   N IIE  +R+QL K
Sbjct: 235 LTVYAWERGSMKT-HFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTK 293

Query: 299 ERPIILDPADPTLNVAEG--YRWDIVAQRASQCLKQDCCYDNRENPISSW 346
            RP+ILDPADPT N+  G    W  +AQ A   L   C  +   +P+SSW
Sbjct: 294 PRPVILDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSW 343


>gi|74229011 2',5'-oligoadenylate synthetase 1 isoform 2 [Homo
           sapiens]
          Length = 364

 Score =  240 bits (613), Expect = 2e-63
 Identities = 141/350 (40%), Positives = 198/350 (56%), Gaps = 14/350 (4%)

Query: 4   MQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLK 63
           M +L +TPA  LD F+  +L P   ++ ++  A+  +  FL++  F   RG    V V K
Sbjct: 1   MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCF---RGSSYPVCVSK 57

Query: 64  VVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTM--WQSQDLLDL 121
           VVK GS G GT LR   + +LV FLS   +FQ+      + ++ I + +   Q +    +
Sbjct: 58  VVKGGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSV 117

Query: 122 GLEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKAC 181
             E        P AL F + +    E +   ++PA+ ALG      +P P++YV LI+ C
Sbjct: 118 KFEVQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEEC 177

Query: 182 GG---PGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALEL 238
                 G F   F+ELQR+F+K RPTKLKSL+RLVKHWYQ     +     LPP YALEL
Sbjct: 178 TDLQKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQN---CKKKLGKLPPQYALEL 234

Query: 239 LTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKK 298
           LT+YAWE G+ +  +F   +GF TV++L++ Y+ +CIYWTKYY   N IIE  +R+QL K
Sbjct: 235 LTVYAWERGSMKT-HFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTK 293

Query: 299 ERPIILDPADPTLNVAEG--YRWDIVAQRASQCLKQDCCYDNRENPISSW 346
            RP+ILDPADPT N+  G    W  +AQ A   L   C  +   +P+SSW
Sbjct: 294 PRPVILDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSW 343


>gi|74229017 2'-5'-oligoadenylate synthetase 2 isoform 2 [Homo
           sapiens]
          Length = 687

 Score =  228 bits (582), Expect = 8e-60
 Identities = 127/352 (36%), Positives = 201/352 (57%), Gaps = 19/352 (5%)

Query: 7   LYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVVK 66
           L++TP   LD F+ ++LQP++ + E++  AV  +  FL++  F+      Q    +++V+
Sbjct: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFR------QSTAKIQIVR 393

Query: 67  VGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIW---KTMW-QSQDLLDLG 122
            GS   GT L++  + +LV F +   S+         +++ I    K  W + ++ L++ 
Sbjct: 394 GGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVS 453

Query: 123 LEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLI---K 179
            E  +   + P  L F+++++   E ++  ++PA+ ALG     S P PEVY  LI   K
Sbjct: 454 FEPPKW--KAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYK 511

Query: 180 ACGGPGN-FCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALEL 238
           +   PG  F   F+ LQRNF++ RPTKLK L+RLVKHWY++  +   P+ +LPP YALEL
Sbjct: 512 SSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALEL 571

Query: 239 LTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKK 298
           LTIYAWE G+   + F   EGF TV++L+ +Y+ +CI+W   Y   +  +   +  QL+K
Sbjct: 572 LTIYAWEQGSGVPD-FDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQK 630

Query: 299 ERPIILDPADPTLNVAEGYR--WDIVAQRASQCLKQDCCYDNRENPISSWNV 348
            RP+ILDPA+PT +V  G R  W ++A+ A + L   C  D   NPI  W V
Sbjct: 631 TRPVILDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKV 682



 Score =  169 bits (429), Expect = 4e-42
 Identities = 122/351 (34%), Positives = 179/351 (50%), Gaps = 30/351 (8%)

Query: 6   ELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVV 65
           +L S PA +L  F+ ++L+P+ E +  + + V T+ + L++         +Q   V  V 
Sbjct: 7   QLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP--------EQFPLVQGVA 58

Query: 66  KVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLDLGL-- 123
             GS+G  TVLR   +  LV F S    FQ+  +  +D+L        ++ D L   L  
Sbjct: 59  IGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILD-------KTGDKLKFCLFT 111

Query: 124 EDLRMEQRVPDALV-FTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYV----SLI 178
           + L+    +  +L  FTIQ     + I+  ++ A+ AL     N  P P +Y     SL 
Sbjct: 112 KWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSL---NDNPSPWIYRELKRSLD 168

Query: 179 KACGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALEL 238
           K    PG F   F+ELQ+ F  +RP KLK L+ L+KHW+QQ  K      +L P YALEL
Sbjct: 169 KTNASPGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSP-YALEL 227

Query: 239 LTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKK 298
           LT+YAWE G  +D NF + EG  TV++L+   E +CIYW   Y   +  I + +  QL+ 
Sbjct: 228 LTVYAWEQGCRKD-NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQS 286

Query: 299 ERPIILDPADPTLNVA-EGYRWDIVAQRASQCLKQDCCYDNRENPISSWNV 348
            RP+ILDP DPT NV+ +   W  + + A   L       + E P  SWNV
Sbjct: 287 ARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLTSPNL--DNELPAPSWNV 335


>gi|74229019 2'-5'-oligoadenylate synthetase 2 isoform 1 [Homo
           sapiens]
          Length = 719

 Score =  228 bits (582), Expect = 8e-60
 Identities = 127/352 (36%), Positives = 201/352 (57%), Gaps = 19/352 (5%)

Query: 7   LYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVVK 66
           L++TP   LD F+ ++LQP++ + E++  AV  +  FL++  F+      Q    +++V+
Sbjct: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFR------QSTAKIQIVR 393

Query: 67  VGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIW---KTMW-QSQDLLDLG 122
            GS   GT L++  + +LV F +   S+         +++ I    K  W + ++ L++ 
Sbjct: 394 GGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVS 453

Query: 123 LEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLI---K 179
            E  +   + P  L F+++++   E ++  ++PA+ ALG     S P PEVY  LI   K
Sbjct: 454 FEPPKW--KAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYK 511

Query: 180 ACGGPGN-FCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALEL 238
           +   PG  F   F+ LQRNF++ RPTKLK L+RLVKHWY++  +   P+ +LPP YALEL
Sbjct: 512 SSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALEL 571

Query: 239 LTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKK 298
           LTIYAWE G+   + F   EGF TV++L+ +Y+ +CI+W   Y   +  +   +  QL+K
Sbjct: 572 LTIYAWEQGSGVPD-FDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQK 630

Query: 299 ERPIILDPADPTLNVAEGYR--WDIVAQRASQCLKQDCCYDNRENPISSWNV 348
            RP+ILDPA+PT +V  G R  W ++A+ A + L   C  D   NPI  W V
Sbjct: 631 TRPVILDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKV 682



 Score =  169 bits (429), Expect = 4e-42
 Identities = 122/351 (34%), Positives = 179/351 (50%), Gaps = 30/351 (8%)

Query: 6   ELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVV 65
           +L S PA +L  F+ ++L+P+ E +  + + V T+ + L++         +Q   V  V 
Sbjct: 7   QLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP--------EQFPLVQGVA 58

Query: 66  KVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLDLGL-- 123
             GS+G  TVLR   +  LV F S    FQ+  +  +D+L        ++ D L   L  
Sbjct: 59  IGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILD-------KTGDKLKFCLFT 111

Query: 124 EDLRMEQRVPDALV-FTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYV----SLI 178
           + L+    +  +L  FTIQ     + I+  ++ A+ AL     N  P P +Y     SL 
Sbjct: 112 KWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSL---NDNPSPWIYRELKRSLD 168

Query: 179 KACGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALEL 238
           K    PG F   F+ELQ+ F  +RP KLK L+ L+KHW+QQ  K      +L P YALEL
Sbjct: 169 KTNASPGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSP-YALEL 227

Query: 239 LTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKK 298
           LT+YAWE G  +D NF + EG  TV++L+   E +CIYW   Y   +  I + +  QL+ 
Sbjct: 228 LTVYAWEQGCRKD-NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQS 286

Query: 299 ERPIILDPADPTLNVA-EGYRWDIVAQRASQCLKQDCCYDNRENPISSWNV 348
            RP+ILDP DPT NV+ +   W  + + A   L       + E P  SWNV
Sbjct: 287 ARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLTSPNL--DNELPAPSWNV 335


>gi|67191208 ubiquitin C [Homo sapiens]
          Length = 685

 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 55/182 (30%), Positives = 90/182 (49%), Gaps = 18/182 (9%)

Query: 343 ISSWNVKRARDIHLTVEQRGYPDF----------NLIVNPYEPIRKVKEKIRRTRGY-SG 391
           +S +N+++   +HL +  RG               L V P + I  VK KI+   G  S 
Sbjct: 132 LSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPSD 191

Query: 392 LQRLSFQVPGSERQLLSSRCSLAKYGIFSHTHIYLLETIPSEIQVFVKNPDGGSYAYAIN 451
            QRL F    + +QL   R +L+ Y I   + ++L+  +   +Q+FVK   G +    + 
Sbjct: 192 QQRLIF----AGKQLEDGR-TLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVE 246

Query: 452 PNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYGIQDSDT--LILSKKKGEA 509
           P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  Y IQ   T  L+L  + G  
Sbjct: 247 PSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQ 306

Query: 510 LF 511
           +F
Sbjct: 307 IF 308



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 54/182 (29%), Positives = 89/182 (48%), Gaps = 18/182 (9%)

Query: 343 ISSWNVKRARDIHLTVEQRGYPDF----------NLIVNPYEPIRKVKEKIRRTRGYS-G 391
           +S +N+++   +HL +  RG               L V P + I  VK KI+   G    
Sbjct: 56  LSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPD 115

Query: 392 LQRLSFQVPGSERQLLSSRCSLAKYGIFSHTHIYLLETIPSEIQVFVKNPDGGSYAYAIN 451
            QRL F    + +QL   R +L+ Y I   + ++L+  +   +Q+FVK   G +    + 
Sbjct: 116 QQRLIF----AGKQLEDGR-TLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVE 170

Query: 452 PNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYGIQDSDT--LILSKKKGEA 509
           P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  Y IQ   T  L+L  + G  
Sbjct: 171 PSDTIENVKAKIQDKEGIPSDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQ 230

Query: 510 LF 511
           +F
Sbjct: 231 IF 232



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 54/182 (29%), Positives = 89/182 (48%), Gaps = 18/182 (9%)

Query: 343 ISSWNVKRARDIHLTVEQRGYPDF----------NLIVNPYEPIRKVKEKIRRTRGYS-G 391
           +S +N+++   +HL +  RG               L V P + I  VK KI+   G    
Sbjct: 208 LSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPD 267

Query: 392 LQRLSFQVPGSERQLLSSRCSLAKYGIFSHTHIYLLETIPSEIQVFVKNPDGGSYAYAIN 451
            QRL F    + +QL   R +L+ Y I   + ++L+  +   +Q+FVK   G +    + 
Sbjct: 268 QQRLIF----AGKQLEDGR-TLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVE 322

Query: 452 PNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYGIQDSDT--LILSKKKGEA 509
           P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  Y IQ   T  L+L  + G  
Sbjct: 323 PSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQ 382

Query: 510 LF 511
           +F
Sbjct: 383 IF 384



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 54/182 (29%), Positives = 89/182 (48%), Gaps = 18/182 (9%)

Query: 343 ISSWNVKRARDIHLTVEQRGYPDF----------NLIVNPYEPIRKVKEKIRRTRGYS-G 391
           +S +N+++   +HL +  RG               L V P + I  VK KI+   G    
Sbjct: 284 LSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPD 343

Query: 392 LQRLSFQVPGSERQLLSSRCSLAKYGIFSHTHIYLLETIPSEIQVFVKNPDGGSYAYAIN 451
            QRL F    + +QL   R +L+ Y I   + ++L+  +   +Q+FVK   G +    + 
Sbjct: 344 QQRLIF----AGKQLEDGR-TLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVE 398

Query: 452 PNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYGIQDSDT--LILSKKKGEA 509
           P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  Y IQ   T  L+L  + G  
Sbjct: 399 PSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQ 458

Query: 510 LF 511
           +F
Sbjct: 459 IF 460



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 54/182 (29%), Positives = 89/182 (48%), Gaps = 18/182 (9%)

Query: 343 ISSWNVKRARDIHLTVEQRGYPDF----------NLIVNPYEPIRKVKEKIRRTRGYS-G 391
           +S +N+++   +HL +  RG               L V P + I  VK KI+   G    
Sbjct: 360 LSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPD 419

Query: 392 LQRLSFQVPGSERQLLSSRCSLAKYGIFSHTHIYLLETIPSEIQVFVKNPDGGSYAYAIN 451
            QRL F    + +QL   R +L+ Y I   + ++L+  +   +Q+FVK   G +    + 
Sbjct: 420 QQRLIF----AGKQLEDGR-TLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVE 474

Query: 452 PNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYGIQDSDT--LILSKKKGEA 509
           P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  Y IQ   T  L+L  + G  
Sbjct: 475 PSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQ 534

Query: 510 LF 511
           +F
Sbjct: 535 IF 536



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 54/182 (29%), Positives = 89/182 (48%), Gaps = 18/182 (9%)

Query: 343 ISSWNVKRARDIHLTVEQRGYPDF----------NLIVNPYEPIRKVKEKIRRTRGYS-G 391
           +S +N+++   +HL +  RG               L V P + I  VK KI+   G    
Sbjct: 436 LSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPD 495

Query: 392 LQRLSFQVPGSERQLLSSRCSLAKYGIFSHTHIYLLETIPSEIQVFVKNPDGGSYAYAIN 451
            QRL F    + +QL   R +L+ Y I   + ++L+  +   +Q+FVK   G +    + 
Sbjct: 496 QQRLIF----AGKQLEDGR-TLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVE 550

Query: 452 PNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYGIQDSDT--LILSKKKGEA 509
           P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  Y IQ   T  L+L  + G  
Sbjct: 551 PSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQ 610

Query: 510 LF 511
           +F
Sbjct: 611 IF 612



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 52/171 (30%), Positives = 84/171 (49%), Gaps = 16/171 (9%)

Query: 343 ISSWNVKRARDIHLTVEQRGYPDF----------NLIVNPYEPIRKVKEKIRRTRGYS-G 391
           +S +N+++   +HL +  RG               L V P + I  VK KI+   G    
Sbjct: 512 LSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPD 571

Query: 392 LQRLSFQVPGSERQLLSSRCSLAKYGIFSHTHIYLLETIPSEIQVFVKNPDGGSYAYAIN 451
            QRL F    + +QL   R +L+ Y I   + ++L+  +   +Q+FVK   G +    + 
Sbjct: 572 QQRLIF----AGKQLEDGR-TLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVE 626

Query: 452 PNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYGIQDSDTLIL 502
           P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  Y IQ   TL L
Sbjct: 627 PSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHL 677



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 48/147 (32%), Positives = 76/147 (51%), Gaps = 8/147 (5%)

Query: 368 LIVNPYEPIRKVKEKIRRTRGYS-GLQRLSFQVPGSERQLLSSRCSLAKYGIFSHTHIYL 426
           L V P + I  VK KI+   G     QRL F    + +QL   R +L+ Y I   + ++L
Sbjct: 15  LEVEPSDTIENVKAKIQDKEGIPPDQQRLIF----AGKQLEDGR-TLSDYNIQKESTLHL 69

Query: 427 LETIPSEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDW 486
           +  +   +Q+FVK   G +    + P+  I  +K +I+D++G+P  QQ+L F G+ L+D 
Sbjct: 70  VLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDG 129

Query: 487 LGLGIYGIQDSDT--LILSKKKGEALF 511
             L  Y IQ   T  L+L  + G  +F
Sbjct: 130 RTLSDYNIQKESTLHLVLRLRGGMQIF 156



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%)

Query: 434 IQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYG 493
           +Q+FVK   G +    + P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  Y 
Sbjct: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60

Query: 494 IQDSDT--LILSKKKGEALF 511
           IQ   T  L+L  + G  +F
Sbjct: 61  IQKESTLHLVLRLRGGMQIF 80


>gi|11024714 ubiquitin B precursor [Homo sapiens]
          Length = 229

 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 52/171 (30%), Positives = 84/171 (49%), Gaps = 16/171 (9%)

Query: 343 ISSWNVKRARDIHLTVEQRGYPDF----------NLIVNPYEPIRKVKEKIRRTRGYS-G 391
           +S +N+++   +HL +  RG               L V P + I  VK KI+   G    
Sbjct: 56  LSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPD 115

Query: 392 LQRLSFQVPGSERQLLSSRCSLAKYGIFSHTHIYLLETIPSEIQVFVKNPDGGSYAYAIN 451
            QRL F    + +QL   R +L+ Y I   + ++L+  +   +Q+FVK   G +    + 
Sbjct: 116 QQRLIF----AGKQLEDGR-TLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVE 170

Query: 452 PNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYGIQDSDTLIL 502
           P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  Y IQ   TL L
Sbjct: 171 PSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHL 221



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 48/147 (32%), Positives = 76/147 (51%), Gaps = 8/147 (5%)

Query: 368 LIVNPYEPIRKVKEKIRRTRGYS-GLQRLSFQVPGSERQLLSSRCSLAKYGIFSHTHIYL 426
           L V P + I  VK KI+   G     QRL F    + +QL   R +L+ Y I   + ++L
Sbjct: 15  LEVEPSDTIENVKAKIQDKEGIPPDQQRLIF----AGKQLEDGR-TLSDYNIQKESTLHL 69

Query: 427 LETIPSEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDW 486
           +  +   +Q+FVK   G +    + P+  I  +K +I+D++G+P  QQ+L F G+ L+D 
Sbjct: 70  VLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDG 129

Query: 487 LGLGIYGIQDSDT--LILSKKKGEALF 511
             L  Y IQ   T  L+L  + G  +F
Sbjct: 130 RTLSDYNIQKESTLHLVLRLRGGMQIF 156



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%)

Query: 434 IQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYG 493
           +Q+FVK   G +    + P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  Y 
Sbjct: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60

Query: 494 IQDSDT--LILSKKKGEALF 511
           IQ   T  L+L  + G  +F
Sbjct: 61  IQKESTLHLVLRLRGGMQIF 80


>gi|208022622 ubiquitin and ribosomal protein S27a precursor [Homo
           sapiens]
          Length = 156

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 26/69 (37%), Positives = 40/69 (57%)

Query: 434 IQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYG 493
           +Q+FVK   G +    + P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  Y 
Sbjct: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60

Query: 494 IQDSDTLIL 502
           IQ   TL L
Sbjct: 61  IQKESTLHL 69


>gi|4506713 ubiquitin and ribosomal protein S27a precursor [Homo
           sapiens]
          Length = 156

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 26/69 (37%), Positives = 40/69 (57%)

Query: 434 IQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYG 493
           +Q+FVK   G +    + P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  Y 
Sbjct: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60

Query: 494 IQDSDTLIL 502
           IQ   TL L
Sbjct: 61  IQKESTLHL 69


>gi|4507761 ubiquitin and ribosomal protein L40 precursor [Homo
           sapiens]
          Length = 128

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 26/69 (37%), Positives = 40/69 (57%)

Query: 434 IQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYG 493
           +Q+FVK   G +    + P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  Y 
Sbjct: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60

Query: 494 IQDSDTLIL 502
           IQ   TL L
Sbjct: 61  IQKESTLHL 69


>gi|77539055 ubiquitin and ribosomal protein L40 precursor [Homo
           sapiens]
          Length = 128

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 26/69 (37%), Positives = 40/69 (57%)

Query: 434 IQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYG 493
           +Q+FVK   G +    + P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  Y 
Sbjct: 1   MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60

Query: 494 IQDSDTLIL 502
           IQ   TL L
Sbjct: 61  IQKESTLHL 69


>gi|4826774 ISG15 ubiquitin-like modifier [Homo sapiens]
          Length = 165

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 38/150 (25%), Positives = 70/150 (46%), Gaps = 5/150 (3%)

Query: 356 LTVEQRGYPDFNLIVNPYEPIRKVKEKIRRTRGYSGLQ-RLSFQVPGSERQLLSSRCSLA 414
           LTV+     +F + ++    + ++K +I +  G    Q RL+    G     L  R  LA
Sbjct: 5   LTVKMLAGNEFQVSLSSSMSVSELKAQITQKIGVHAFQQRLAVHPSGVA---LQDRVPLA 61

Query: 415 KYGIF-SHTHIYLLETIPSEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQ 473
             G+    T + +++     + + V+N  G S  Y +     +  LKQQ+   +G+    
Sbjct: 62  SQGLGPGSTVLLVVDKCDEPLSILVRNNKGRSSTYEVRLTQTVAHLKQQVSGLEGVQDDL 121

Query: 474 QQLEFQGQVLQDWLGLGIYGIQDSDTLILS 503
             L F+G+ L+D L LG YG++   T+ ++
Sbjct: 122 FWLTFEGKPLEDQLPLGEYGLKPLSTVFMN 151


>gi|74229021 2'-5'-oligoadenylate synthetase 2 isoform 3 [Homo
           sapiens]
          Length = 172

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 8/100 (8%)

Query: 6   ELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVV 65
           +L S PA +L  F+ ++L+P+ E +  + + V T+ + L++         +Q   V  V 
Sbjct: 7   QLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP--------EQFPLVQGVA 58

Query: 66  KVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVL 105
             GS+G  TVLR   +  LV F S    FQ+  +  +D+L
Sbjct: 59  IGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDIL 98


>gi|239757745 PREDICTED: similar to hCG1790904 [Homo sapiens]
          Length = 334

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 25/71 (35%), Positives = 41/71 (57%)

Query: 432 SEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGI 491
           +++Q+FVK   G +    + P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  
Sbjct: 67  TKLQIFVKTLRGKTITLEVEPSDAIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD 126

Query: 492 YGIQDSDTLIL 502
             IQ   TL L
Sbjct: 127 CNIQKEPTLHL 137


>gi|239752254 PREDICTED: similar to hCG1790904 [Homo sapiens]
          Length = 334

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 25/71 (35%), Positives = 41/71 (57%)

Query: 432 SEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGI 491
           +++Q+FVK   G +    + P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  
Sbjct: 67  TKLQIFVKTLRGKTITLEVEPSDAIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD 126

Query: 492 YGIQDSDTLIL 502
             IQ   TL L
Sbjct: 127 CNIQKEPTLHL 137


>gi|239746765 PREDICTED: similar to hCG1790904 [Homo sapiens]
          Length = 334

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 25/71 (35%), Positives = 41/71 (57%)

Query: 432 SEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGI 491
           +++Q+FVK   G +    + P+  I  +K +I+D++G+P  QQ+L F G+ L+D   L  
Sbjct: 67  TKLQIFVKTLRGKTITLEVEPSDAIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSD 126

Query: 492 YGIQDSDTLIL 502
             IQ   TL L
Sbjct: 127 CNIQKEPTLHL 137


>gi|222352096 ubiquitin D [Homo sapiens]
          Length = 165

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 39/156 (25%), Positives = 73/156 (46%), Gaps = 12/156 (7%)

Query: 354 IHLTVEQRGYPDFNLIVNPYEPIRKVKEKIRRTRGYSGLQRLSFQVPGSERQLLSSRCSL 413
           +H+  E+     F+   NPY+ ++K+KE +R          +  QV     ++L  R SL
Sbjct: 10  VHVRSEEWDLMTFD--ANPYDSVKKIKEHVRSKTKVP----VQDQVLLLGSKILKPRRSL 63

Query: 414 AKYGIFSHTHIYLLETI--PS--EIQVFV--KNPDGGSYAYAINPNSFILGLKQQIEDQQ 467
           + YGI     I+L   +  PS  E+ +F+     +   +   +  +S +  +K  IE + 
Sbjct: 64  SSYGIDKEKTIHLTLKVVKPSDEELPLFLVESGDEAKRHLLQVRRSSSVAQVKAMIETKT 123

Query: 468 GLPKKQQQLEFQGQVLQDWLGLGIYGIQDSDTLILS 503
           G+  + Q +   G+ L+D   +  YGI+  + L L+
Sbjct: 124 GIIPETQIVTCNGKRLEDGKMMADYGIRKGNLLFLA 159


>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 36.2 bits (82), Expect = 0.073
 Identities = 18/64 (28%), Positives = 32/64 (50%)

Query: 431 PSEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLG 490
           P  ++V VK  D  +  + +     +   K+ I     +P ++Q+L +QG+VLQD   L 
Sbjct: 14  PDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQ 73

Query: 491 IYGI 494
            Y +
Sbjct: 74  EYNV 77


>gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 36.2 bits (82), Expect = 0.073
 Identities = 18/64 (28%), Positives = 32/64 (50%)

Query: 431 PSEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLG 490
           P  ++V VK  D  +  + +     +   K+ I     +P ++Q+L +QG+VLQD   L 
Sbjct: 14  PDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQ 73

Query: 491 IYGI 494
            Y +
Sbjct: 74  EYNV 77


>gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 36.2 bits (82), Expect = 0.073
 Identities = 18/64 (28%), Positives = 32/64 (50%)

Query: 431 PSEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLG 490
           P  ++V VK  D  +  + +     +   K+ I     +P ++Q+L +QG+VLQD   L 
Sbjct: 14  PDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQ 73

Query: 491 IYGI 494
            Y +
Sbjct: 74  EYNV 77


>gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]
          Length = 1132

 Score = 36.2 bits (82), Expect = 0.073
 Identities = 18/64 (28%), Positives = 32/64 (50%)

Query: 431 PSEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLG 490
           P  ++V VK  D  +  + +     +   K+ I     +P ++Q+L +QG+VLQD   L 
Sbjct: 14  PDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQ 73

Query: 491 IYGI 494
            Y +
Sbjct: 74  EYNV 77


>gi|4506387 UV excision repair protein RAD23 homolog B [Homo
           sapiens]
          Length = 409

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 21/80 (26%), Positives = 42/80 (52%), Gaps = 3/80 (3%)

Query: 434 IQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQG---LPKKQQQLEFQGQVLQDWLGLG 490
           +QV +K     ++   I+P   +  LK++IE ++G    P   Q+L + G++L D   L 
Sbjct: 1   MQVTLKTLQQQTFKIDIDPEETVKALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTALK 60

Query: 491 IYGIQDSDTLILSKKKGEAL 510
            Y I + + +++   K +A+
Sbjct: 61  EYKIDEKNFVVVMVTKPKAV 80


>gi|7657667 ubiquitin-like 4 [Homo sapiens]
          Length = 157

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 21/72 (29%), Positives = 36/72 (50%)

Query: 434 IQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYG 493
           +Q+ VK   G   +  +  +  +  LKQ + ++  +P +QQ+L F+G+ L D   L  Y 
Sbjct: 1   MQLTVKALQGRECSLQVPEDELVSTLKQLVSEKLNVPVRQQRLLFKGKALADGKRLSDYS 60

Query: 494 IQDSDTLILSKK 505
           I  +  L L  K
Sbjct: 61  IGPNSKLNLVVK 72


>gi|5453760 neural precursor cell expressed, developmentally
           down-regulated 8 [Homo sapiens]
          Length = 81

 Score = 33.9 bits (76), Expect = 0.36
 Identities = 14/48 (29%), Positives = 28/48 (58%)

Query: 438 VKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQD 485
           VK   G      I P   +  +K+++E+++G+P +QQ+L + G+ + D
Sbjct: 5   VKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMND 52


>gi|171906567 peripheral benzodiazepine receptor-associated protein 1
            isoform b [Homo sapiens]
          Length = 1797

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 5/69 (7%)

Query: 123  LEDLRMEQRVPDALVFTIQTRGTAE-----PITVTIVPAYRALGPSLPNSQPPPEVYVSL 177
            L  L++ Q   + +V T+   G +      PIT  + PA      S P+  P PE    L
Sbjct: 983  LSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAPASLPARVSCPSPHPSPEARAPL 1042

Query: 178  IKACGGPGN 186
              A  GPG+
Sbjct: 1043 ASASPGPGD 1051


>gi|171906559 peripheral benzodiazepine receptor-associated protein 1
            isoform a [Homo sapiens]
          Length = 1857

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 5/69 (7%)

Query: 123  LEDLRMEQRVPDALVFTIQTRGTAE-----PITVTIVPAYRALGPSLPNSQPPPEVYVSL 177
            L  L++ Q   + +V T+   G +      PIT  + PA      S P+  P PE    L
Sbjct: 1043 LSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAPASLPARVSCPSPHPSPEARAPL 1102

Query: 178  IKACGGPGN 186
              A  GPG+
Sbjct: 1103 ASASPGPGD 1111


>gi|5454180 zinc finger protein 193 [Homo sapiens]
          Length = 394

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 14/32 (43%), Positives = 21/32 (65%), Gaps = 1/32 (3%)

Query: 13  SRLDSFVAQWLQPHREWKEEVLDAVRTVEEFL 44
           +RL     QWL+PH   KE++LD +  +E+FL
Sbjct: 71  TRLQELCYQWLRPHVSTKEQILDLL-VLEQFL 101


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,999,244
Number of Sequences: 37866
Number of extensions: 973039
Number of successful extensions: 2522
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 2401
Number of HSP's gapped (non-prelim): 84
length of query: 514
length of database: 18,247,518
effective HSP length: 107
effective length of query: 407
effective length of database: 14,195,856
effective search space: 5777713392
effective search space used: 5777713392
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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