Guide to the Human Genome
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Search of human proteins with 103485143

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|103485143 defensin, beta 106B precursor [Homo sapiens]
         (65 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22748611 defensin, beta 106A precursor [Homo sapiens]              141   1e-34
gi|103485143 defensin, beta 106B precursor [Homo sapiens]             141   1e-34
gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]            39   9e-04
gi|50344744 beta-defensin 108B [Homo sapiens]                          39   9e-04
gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]            37   0.003
gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]            37   0.003
gi|116517226 beta-defensin 135 [Homo sapiens]                          35   0.010
gi|22748617 defensin, beta 105A precursor [Homo sapiens]               35   0.013
gi|103485141 defensin, beta 105B precursor [Homo sapiens]              35   0.013
gi|239744548 PREDICTED: hypothetical protein XP_002343194 [Homo ...    35   0.017
gi|74136827 beta-defensin 134 [Homo sapiens]                           35   0.017
gi|76563936 defensin, beta 125 preproprotein [Homo sapiens]            35   0.017
gi|82734219 beta-defensin 114 [Homo sapiens]                           35   0.017
gi|82734214 beta-defensin 111 [Homo sapiens]                           34   0.029
gi|239743480 PREDICTED: hypothetical protein XP_002342858 [Homo ...    33   0.037
gi|239742274 PREDICTED: hypothetical protein XP_002342470 [Homo ...    33   0.037
gi|149944551 defensin, beta 131 [Homo sapiens]                         33   0.037
gi|239743495 PREDICTED: hypothetical protein XP_002342880 [Homo ...    33   0.064
gi|169173154 PREDICTED: hypothetical protein [Homo sapiens]            32   0.083
gi|239754319 PREDICTED: defensin, beta 133 [Homo sapiens]              32   0.083
gi|239753810 PREDICTED: similar to beta-defensin 130 [Homo sapiens]    32   0.083
gi|169172390 PREDICTED: similar to defensin, beta 131 [Homo sapi...    32   0.083
gi|239748864 PREDICTED: defensin, beta 133 [Homo sapiens]              32   0.083
gi|239748374 PREDICTED: hypothetical protein XP_002346650 [Homo ...    32   0.083
gi|169172908 PREDICTED: similar to beta-defensin 130 [Homo sapiens]    32   0.083
gi|239742893 PREDICTED: beta-defensin 133 [Homo sapiens]               32   0.083
gi|239742299 PREDICTED: hypothetical protein XP_002342487 [Homo ...    32   0.083
gi|83699414 beta-defensin 130 [Homo sapiens]                           32   0.083
gi|42558283 gap junction protein beta 2 [Homo sapiens]                 32   0.11 
gi|83582794 beta-defensin 110 [Homo sapiens]                           32   0.11 

>gi|22748611 defensin, beta 106A precursor [Homo sapiens]
          Length = 65

 Score =  141 bits (355), Expect = 1e-34
 Identities = 65/65 (100%), Positives = 65/65 (100%)

Query: 1  MRTFLFLFAVLFFLTPAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPC 60
          MRTFLFLFAVLFFLTPAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPC
Sbjct: 1  MRTFLFLFAVLFFLTPAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPC 60

Query: 61 GSIID 65
          GSIID
Sbjct: 61 GSIID 65


>gi|103485143 defensin, beta 106B precursor [Homo sapiens]
          Length = 65

 Score =  141 bits (355), Expect = 1e-34
 Identities = 65/65 (100%), Positives = 65/65 (100%)

Query: 1  MRTFLFLFAVLFFLTPAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPC 60
          MRTFLFLFAVLFFLTPAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPC
Sbjct: 1  MRTFLFLFAVLFFLTPAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPC 60

Query: 61 GSIID 65
          GSIID
Sbjct: 61 GSIID 65


>gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 73

 Score = 38.9 bits (89), Expect = 9e-04
 Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 4/57 (7%)

Query: 1  MRTFLFLFAVLFFLT---PAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCC 54
          MR  + LFA+ FF++   PA+  F  E C +  G+C++ C + E  +  C  S  CC
Sbjct: 1  MRIAVLLFAIFFFMSQVLPARGKF-KEICERPNGSCRDFCLETEIHVGRCLNSRPCC 56


>gi|50344744 beta-defensin 108B [Homo sapiens]
          Length = 73

 Score = 38.9 bits (89), Expect = 9e-04
 Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 4/57 (7%)

Query: 1  MRTFLFLFAVLFFLT---PAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCC 54
          MR  + LFA+ FF++   PA+  F  E C +  G+C++ C + E  +  C  S  CC
Sbjct: 1  MRIAVLLFAIFFFMSQVLPARGKF-KEICERPNGSCRDFCLETEIHVGRCLNSQPCC 56


>gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 83

 Score = 37.4 bits (85), Expect = 0.003
 Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 4/57 (7%)

Query: 1  MRTFLFLFAVLFFLT---PAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCC 54
          +R  + LFA+ FF++   PA+  F  E C +  G+C++ C + E  +  C  S  CC
Sbjct: 11 VRIAVLLFAIFFFMSQVLPARGKF-KEICERPNGSCRDFCLETEIHVGRCLNSRPCC 66


>gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 83

 Score = 37.4 bits (85), Expect = 0.003
 Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 4/57 (7%)

Query: 1  MRTFLFLFAVLFFLT---PAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCC 54
          +R  + LFA+ FF++   PA+  F  E C +  G+C++ C + E  +  C  S  CC
Sbjct: 11 VRIAVLLFAIFFFMSQVLPARGKF-KEICERPNGSCRDFCLETEIHVGRCLNSRPCC 66


>gi|116517226 beta-defensin 135 [Homo sapiens]
          Length = 77

 Score = 35.4 bits (80), Expect = 0.010
 Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 6/56 (10%)

Query: 5  LFLFAVLFFLTPAK---NAFFDE---KCNKLKGTCKNNCGKNEELIALCQKSLKCC 54
          L +  +LF++ P +   N +  +    C +L+GTC+  C KNE+   LC     CC
Sbjct: 10 LVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCC 65


>gi|22748617 defensin, beta 105A precursor [Homo sapiens]
          Length = 78

 Score = 35.0 bits (79), Expect = 0.013
 Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 16/70 (22%)

Query: 2  RTFLFLFAVLFFLT----------------PAKNAFFDEKCNKLKGTCKNNCGKNEELIA 45
          +TF FLFA+ F L                 P+      E C   +G C+  C +NE+   
Sbjct: 6  KTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDG 65

Query: 46 LCQKSLKCCR 55
           C+ +  CCR
Sbjct: 66 NCRLNFLCCR 75


>gi|103485141 defensin, beta 105B precursor [Homo sapiens]
          Length = 78

 Score = 35.0 bits (79), Expect = 0.013
 Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 16/70 (22%)

Query: 2  RTFLFLFAVLFFLT----------------PAKNAFFDEKCNKLKGTCKNNCGKNEELIA 45
          +TF FLFA+ F L                 P+      E C   +G C+  C +NE+   
Sbjct: 6  KTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDG 65

Query: 46 LCQKSLKCCR 55
           C+ +  CCR
Sbjct: 66 NCRLNFLCCR 75


>gi|239744548 PREDICTED: hypothetical protein XP_002343194 [Homo
           sapiens]
          Length = 192

 Score = 34.7 bits (78), Expect = 0.017
 Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 5/54 (9%)

Query: 5   LFLFAVLFFLTPAKNAF--FDEKCNKLKGTCKNN-CGKNEELIALCQKSLKCCR 55
           L LF++L  L+P + A    +  C  L G C+ + C   E+ I  C++ +KCCR
Sbjct: 73  LLLFSIL--LSPVRGALGPAEVHCLSLSGVCRRDVCKVVEDQIGACRRRMKCCR 124


>gi|74136827 beta-defensin 134 [Homo sapiens]
          Length = 66

 Score = 34.7 bits (78), Expect = 0.017
 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 7/60 (11%)

Query: 1  MRTFLFLFAVLFFLTP------AKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCC 54
          M+  L +F  LF   P      + ++   +KC K  G C+  C ++E L+A C   L+CC
Sbjct: 1  MKPLLVVFVFLFLWDPVLAGINSLSSEMHKKCYK-NGICRLECYESEMLVAYCMFQLECC 59


>gi|76563936 defensin, beta 125 preproprotein [Homo sapiens]
          Length = 156

 Score = 34.7 bits (78), Expect = 0.017
 Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 2/59 (3%)

Query: 1  MRTFLFLFAVLFFLTPA-KNAFFDEKCNKLK-GTCKNNCGKNEELIALCQKSLKCCRTI 57
          M   +  F +   LT   K +F  +KC K   G C+  C   E  I LC+  L CC +I
Sbjct: 1  MNILMLTFIICGLLTRVTKGSFEPQKCWKNNVGHCRRRCLDTERYILLCRNKLSCCISI 59


>gi|82734219 beta-defensin 114 [Homo sapiens]
          Length = 69

 Score = 34.7 bits (78), Expect = 0.017
 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 3/59 (5%)

Query: 1  MRTFLFLFAVLF--FLTPAKNAFFD-EKCNKLKGTCKNNCGKNEELIALCQKSLKCCRT 56
          MR F +L  + +  F+ PA     + ++C K  G CK +C ++E+ I +C    K C T
Sbjct: 1  MRIFYYLHFLCYVTFILPATCTLVNADRCTKRYGRCKRDCLESEKQIDICSLPRKICCT 59


>gi|82734214 beta-defensin 111 [Homo sapiens]
          Length = 67

 Score = 33.9 bits (76), Expect = 0.029
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 10/64 (15%)

Query: 1  MRTFLFLFAVLFFLT--PAKNAFFD-------EKCNKLKGTCKNNCGKNEELIALC-QKS 50
          M+  LF F + F++T  PAK  + +        +C    G CKN C +NE  IA C +  
Sbjct: 1  MKIQLFFFILHFWVTILPAKKKYPEYGSLDLRRECRIGNGQCKNQCHENEIRIAYCIRPG 60

Query: 51 LKCC 54
            CC
Sbjct: 61 THCC 64


>gi|239743480 PREDICTED: hypothetical protein XP_002342858 [Homo
          sapiens]
          Length = 87

 Score = 33.5 bits (75), Expect = 0.037
 Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 6/61 (9%)

Query: 1  MRTFLFLFAVLFF---LTPAKNAF--FDEKCNKLKGTCKNN-CGKNEELIALCQKSLKCC 54
          MR  L L  +L F   L+P +      +  C  L G C+ + C   E+ I  C++ +KCC
Sbjct: 1  MRLHLLLLILLLFSILLSPVRGGLGPAEGHCLNLFGVCRTDVCNIVEDQIGACRRRMKCC 60

Query: 55 R 55
          R
Sbjct: 61 R 61


>gi|239742274 PREDICTED: hypothetical protein XP_002342470 [Homo
          sapiens]
          Length = 87

 Score = 33.5 bits (75), Expect = 0.037
 Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 6/61 (9%)

Query: 1  MRTFLFLFAVLF--FLTPAKNAFF---DEKCNKLKGTCKNN-CGKNEELIALCQKSLKCC 54
          MR  L L  +LF   L+P         +  C  L G C+ + C   E+ I  C++ +KCC
Sbjct: 1  MRLHLLLLILLFSILLSPGNKGGLGPAEGHCLNLSGVCRRDVCKVVEDQIGACRRKMKCC 60

Query: 55 R 55
          R
Sbjct: 61 R 61


>gi|149944551 defensin, beta 131 [Homo sapiens]
          Length = 70

 Score = 33.5 bits (75), Expect = 0.037
 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 3/58 (5%)

Query: 1  MRTFLFLFAVL---FFLTPAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCR 55
          MR   F+F VL   F + PA++   +++C      C+  C  +E  I  C     CC+
Sbjct: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCK 58


>gi|239743495 PREDICTED: hypothetical protein XP_002342880 [Homo
          sapiens]
          Length = 70

 Score = 32.7 bits (73), Expect = 0.064
 Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 3/58 (5%)

Query: 1  MRTFLFLFAVLFFLT---PAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCR 55
          MR   F+F VL  ++   PA++   +++C      C+  C  +E +I  C     CC+
Sbjct: 1  MRVLFFVFGVLSLMSTVPPARSFISNDECPSEYYHCRLKCNADEHVIRYCAYFSICCK 58


>gi|169173154 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 70

 Score = 32.3 bits (72), Expect = 0.083
 Identities = 16/58 (27%), Positives = 27/58 (46%), Gaps = 3/58 (5%)

Query: 1  MRTFLFLFAVLFFLT---PAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCR 55
          MR   F+F VL  ++   PA++   +++C      C+  C  +E  I  C     CC+
Sbjct: 1  MRVLFFVFGVLSLMSTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCK 58


>gi|239754319 PREDICTED: defensin, beta 133 [Homo sapiens]
          Length = 61

 Score = 32.3 bits (72), Expect = 0.083
 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 5/54 (9%)

Query: 1  MRTFLFLFAVLFFLTPA----KNAFFDE-KCNKLKGTCKNNCGKNEELIALCQK 49
          M+  +FLF + FFL P     K A  D   C  ++G C++ C   E+ I  C K
Sbjct: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTK 54


>gi|239753810 PREDICTED: similar to beta-defensin 130 [Homo sapiens]
          Length = 128

 Score = 32.3 bits (72), Expect = 0.083
 Identities = 12/33 (36%), Positives = 20/33 (60%), Gaps = 1/33 (3%)

Query: 24  EKCNKLKGTCKNN-CGKNEELIALCQKSLKCCR 55
           ++C  LKG C++  C   ++ I +C +  KCCR
Sbjct: 78  KQCIALKGVCRDKLCSTLDDTIGICNEGKKCCR 110


>gi|169172390 PREDICTED: similar to defensin, beta 131 [Homo
          sapiens]
          Length = 70

 Score = 32.3 bits (72), Expect = 0.083
 Identities = 16/58 (27%), Positives = 27/58 (46%), Gaps = 3/58 (5%)

Query: 1  MRTFLFLFAVLFFLT---PAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCR 55
          MR   F+F VL  ++   PA++   +++C      C+  C  +E  I  C     CC+
Sbjct: 1  MRVLFFVFGVLSLMSTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCK 58


>gi|239748864 PREDICTED: defensin, beta 133 [Homo sapiens]
          Length = 61

 Score = 32.3 bits (72), Expect = 0.083
 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 5/54 (9%)

Query: 1  MRTFLFLFAVLFFLTPA----KNAFFDE-KCNKLKGTCKNNCGKNEELIALCQK 49
          M+  +FLF + FFL P     K A  D   C  ++G C++ C   E+ I  C K
Sbjct: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTK 54


>gi|239748374 PREDICTED: hypothetical protein XP_002346650 [Homo
           sapiens]
          Length = 128

 Score = 32.3 bits (72), Expect = 0.083
 Identities = 12/33 (36%), Positives = 20/33 (60%), Gaps = 1/33 (3%)

Query: 24  EKCNKLKGTCKNN-CGKNEELIALCQKSLKCCR 55
           ++C  LKG C++  C   ++ I +C +  KCCR
Sbjct: 78  KQCIALKGVCRDKLCSTLDDTIGICNEGKKCCR 110


>gi|169172908 PREDICTED: similar to beta-defensin 130 [Homo
          sapiens]
          Length = 79

 Score = 32.3 bits (72), Expect = 0.083
 Identities = 12/33 (36%), Positives = 20/33 (60%), Gaps = 1/33 (3%)

Query: 24 EKCNKLKGTCKNN-CGKNEELIALCQKSLKCCR 55
          ++C  LKG C++  C   ++ I +C +  KCCR
Sbjct: 29 KQCIALKGVCRDKLCSTLDDTIGICNEGKKCCR 61


>gi|239742893 PREDICTED: beta-defensin 133 [Homo sapiens]
          Length = 61

 Score = 32.3 bits (72), Expect = 0.083
 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 5/54 (9%)

Query: 1  MRTFLFLFAVLFFLTPA----KNAFFDE-KCNKLKGTCKNNCGKNEELIALCQK 49
          M+  +FLF + FFL P     K A  D   C  ++G C++ C   E+ I  C K
Sbjct: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTK 54


>gi|239742299 PREDICTED: hypothetical protein XP_002342487 [Homo
           sapiens]
          Length = 128

 Score = 32.3 bits (72), Expect = 0.083
 Identities = 12/33 (36%), Positives = 20/33 (60%), Gaps = 1/33 (3%)

Query: 24  EKCNKLKGTCKNN-CGKNEELIALCQKSLKCCR 55
           ++C  LKG C++  C   ++ I +C +  KCCR
Sbjct: 78  KQCIALKGVCRDKLCSTLDDTIGICNEGKKCCR 110


>gi|83699414 beta-defensin 130 [Homo sapiens]
          Length = 79

 Score = 32.3 bits (72), Expect = 0.083
 Identities = 12/33 (36%), Positives = 20/33 (60%), Gaps = 1/33 (3%)

Query: 24 EKCNKLKGTCKNN-CGKNEELIALCQKSLKCCR 55
          ++C  LKG C++  C   ++ I +C +  KCCR
Sbjct: 29 KQCIALKGVCRDKLCSTLDDTIGICNEGKKCCR 61


>gi|42558283 gap junction protein beta 2 [Homo sapiens]
          Length = 226

 Score = 32.0 bits (71), Expect = 0.11
 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 4/39 (10%)

Query: 3  TFLFLFAVLFFLTPAKNAFFDEK----CNKLKGTCKNNC 37
          T LF+F ++  +  AK  + DE+    CN L+  CKN C
Sbjct: 26 TVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCKNVC 64


>gi|83582794 beta-defensin 110 [Homo sapiens]
          Length = 62

 Score = 32.0 bits (71), Expect = 0.11
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 7/61 (11%)

Query: 1  MRTFLFLFAVLFFLT--PAKNAFFD----EKCNKLKGTCKNNCGKNEELIALCQK-SLKC 53
          M+  LF F + F++T  PA++ F      E+C K++G CK  C   E     C K   +C
Sbjct: 1  MKIQLFFFILHFWVTILPARSNFEPKYRFERCEKVRGICKTFCDDVEYDYGYCIKWRSQC 60

Query: 54 C 54
          C
Sbjct: 61 C 61


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.331    0.142    0.469 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,517,608
Number of Sequences: 37866
Number of extensions: 87042
Number of successful extensions: 410
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 367
Number of HSP's gapped (non-prelim): 73
length of query: 65
length of database: 18,247,518
effective HSP length: 38
effective length of query: 27
effective length of database: 16,808,610
effective search space: 453832470
effective search space used: 453832470
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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