Guide to the Human Genome
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Search of human proteins with 102467481

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|102467481 sphingomyelin phosphodiesterase 4 isoform 2 [Homo
sapiens]
         (866 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|102467481 sphingomyelin phosphodiesterase 4 isoform 2 [Homo s...  1761   0.0  
gi|102467484 sphingomyelin phosphodiesterase 4 isoform 1 [Homo s...  1690   0.0  
gi|160420295 hypothetical protein LOC85459 [Homo sapiens]              39   0.021
gi|149192855 HLA-B associated transcript 2-like [Homo sapiens]         33   1.1  
gi|78000158 eukaryotic translation initiation factor 2B, subunit...    32   1.9  
gi|78000156 eukaryotic translation initiation factor 2B, subunit...    32   1.9  
gi|187607323 eukaryotic translation initiation factor 2B, subuni...    32   1.9  
gi|23510413 sorting nexin 26 [Homo sapiens]                            32   1.9  
gi|18959210 WIRE protein [Homo sapiens]                                32   1.9  
gi|87298937 centrosomal protein 110kDa [Homo sapiens]                  32   1.9  
gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]                32   2.5  
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    32   2.5  
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]    32   2.5  
gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]                32   2.5  
gi|239757337 PREDICTED: hypothetical protein XP_002345251 [Homo ...    32   2.5  
gi|239751874 PREDICTED: hypothetical protein XP_002348034 [Homo ...    32   2.5  
gi|11386183 WAS protein family, member 2 [Homo sapiens]                32   2.5  
gi|100913204 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 iso...    32   2.5  
gi|100913202 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 iso...    32   2.5  
gi|132566527 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 iso...    32   2.5  
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     32   3.3  
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     32   3.3  
gi|55741571 leucine rich repeat and fibronectin type III domain ...    32   3.3  
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]         32   3.3  
gi|38505213 YTH domain containing 2 [Homo sapiens]                     32   3.3  
gi|148236531 hypothetical protein LOC339779 [Homo sapiens]             32   3.3  
gi|12232415 hypothetical protein LOC64762 [Homo sapiens]               31   4.3  
gi|45580719 osteoclast-associated receptor isoform 1 [Homo sapiens]    31   4.3  
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]    31   4.3  
gi|54112420 Cas-Br-M (murine) ecotropic retroviral transforming ...    31   5.7  

>gi|102467481 sphingomyelin phosphodiesterase 4 isoform 2 [Homo
           sapiens]
          Length = 866

 Score = 1761 bits (4561), Expect = 0.0
 Identities = 866/866 (100%), Positives = 866/866 (100%)

Query: 1   MTTFGAVAEWRLPSLRRATLWIPQWFAKKAIFNSPLEAAMAFPHLQQPSFLLASLKADSI 60
           MTTFGAVAEWRLPSLRRATLWIPQWFAKKAIFNSPLEAAMAFPHLQQPSFLLASLKADSI
Sbjct: 1   MTTFGAVAEWRLPSLRRATLWIPQWFAKKAIFNSPLEAAMAFPHLQQPSFLLASLKADSI 60

Query: 61  NKPFAQQCQDLVKVIEDFPAKELHTIFPWLVESIFGSLDGVLVGWNLRCLQGRVNPVEYS 120
           NKPFAQQCQDLVKVIEDFPAKELHTIFPWLVESIFGSLDGVLVGWNLRCLQGRVNPVEYS
Sbjct: 61  NKPFAQQCQDLVKVIEDFPAKELHTIFPWLVESIFGSLDGVLVGWNLRCLQGRVNPVEYS 120

Query: 121 IVMEFLDPGGPMMKLVYKLQAEDYKFDFPVSYLPGPVKASIQECILPDSPLYHNKVQFTP 180
           IVMEFLDPGGPMMKLVYKLQAEDYKFDFPVSYLPGPVKASIQECILPDSPLYHNKVQFTP
Sbjct: 121 IVMEFLDPGGPMMKLVYKLQAEDYKFDFPVSYLPGPVKASIQECILPDSPLYHNKVQFTP 180

Query: 181 TGGLGLNLALNPFEYYIFFFALSLITQKPLPVSLHVRTSDCAYFILVDRYLSWFLPTEGS 240
           TGGLGLNLALNPFEYYIFFFALSLITQKPLPVSLHVRTSDCAYFILVDRYLSWFLPTEGS
Sbjct: 181 TGGLGLNLALNPFEYYIFFFALSLITQKPLPVSLHVRTSDCAYFILVDRYLSWFLPTEGS 240

Query: 241 VPPPLSSSPGGTSPSPPPRTPAIPFASYGLHHTSLLKRHISHQTSVNADPASHEIWRSET 300
           VPPPLSSSPGGTSPSPPPRTPAIPFASYGLHHTSLLKRHISHQTSVNADPASHEIWRSET
Sbjct: 241 VPPPLSSSPGGTSPSPPPRTPAIPFASYGLHHTSLLKRHISHQTSVNADPASHEIWRSET 300

Query: 301 LLQVFVEMWLHHYSLEMYQKMQSPHAKLEVLHYRLSVSSALYSPAQPSLQALHAYQESFT 360
           LLQVFVEMWLHHYSLEMYQKMQSPHAKLEVLHYRLSVSSALYSPAQPSLQALHAYQESFT
Sbjct: 301 LLQVFVEMWLHHYSLEMYQKMQSPHAKLEVLHYRLSVSSALYSPAQPSLQALHAYQESFT 360

Query: 361 PTEEHVLVVRLLLKHLHAFANSLKPEQASPSAHSHATSPLEEFKRAAVPRFVQQKLYLFL 420
           PTEEHVLVVRLLLKHLHAFANSLKPEQASPSAHSHATSPLEEFKRAAVPRFVQQKLYLFL
Sbjct: 361 PTEEHVLVVRLLLKHLHAFANSLKPEQASPSAHSHATSPLEEFKRAAVPRFVQQKLYLFL 420

Query: 421 QHCFGHWPLDASFRAVLEMWLSYLQPWRYAPDKQAPGSDSQPRCVSEKWAPFVQENLLMY 480
           QHCFGHWPLDASFRAVLEMWLSYLQPWRYAPDKQAPGSDSQPRCVSEKWAPFVQENLLMY
Sbjct: 421 QHCFGHWPLDASFRAVLEMWLSYLQPWRYAPDKQAPGSDSQPRCVSEKWAPFVQENLLMY 480

Query: 481 TKLFVGFLNRALRTDLVSPKHALMVFRVAKVFAQPNLAEMIQKGEQLFLEPELVIPHRQH 540
           TKLFVGFLNRALRTDLVSPKHALMVFRVAKVFAQPNLAEMIQKGEQLFLEPELVIPHRQH
Sbjct: 481 TKLFVGFLNRALRTDLVSPKHALMVFRVAKVFAQPNLAEMIQKGEQLFLEPELVIPHRQH 540

Query: 541 RLFTAPTFTGSFLSPWPPAVTDASFKVKSHVYSLEGQDCKYTPMFGPEARTLVLRLAQLI 600
           RLFTAPTFTGSFLSPWPPAVTDASFKVKSHVYSLEGQDCKYTPMFGPEARTLVLRLAQLI
Sbjct: 541 RLFTAPTFTGSFLSPWPPAVTDASFKVKSHVYSLEGQDCKYTPMFGPEARTLVLRLAQLI 600

Query: 601 TQAKHTAKSISDQCAESPAGHSFLSWLGFSSMDTNGSYTANDLDEMGQDSVRKTDEYLEK 660
           TQAKHTAKSISDQCAESPAGHSFLSWLGFSSMDTNGSYTANDLDEMGQDSVRKTDEYLEK
Sbjct: 601 TQAKHTAKSISDQCAESPAGHSFLSWLGFSSMDTNGSYTANDLDEMGQDSVRKTDEYLEK 660

Query: 661 ALEYLRQIFRLSEAQLRQFTLALGTTQDENGKKQLPDCIVGEDGLILTPLGRYQIINGLR 720
           ALEYLRQIFRLSEAQLRQFTLALGTTQDENGKKQLPDCIVGEDGLILTPLGRYQIINGLR
Sbjct: 661 ALEYLRQIFRLSEAQLRQFTLALGTTQDENGKKQLPDCIVGEDGLILTPLGRYQIINGLR 720

Query: 721 RFEIEYQGDPELQPIRSYEIASLVRTLFRLSSAINHRFAGQMAALCSRDDFLGSFCRYHL 780
           RFEIEYQGDPELQPIRSYEIASLVRTLFRLSSAINHRFAGQMAALCSRDDFLGSFCRYHL
Sbjct: 721 RFEIEYQGDPELQPIRSYEIASLVRTLFRLSSAINHRFAGQMAALCSRDDFLGSFCRYHL 780

Query: 781 TEPGLASRHLLSPVGRRQVAGHTRGPRLSLRFLGSYRTLVSLLLAFFVASLFCVGPLPCT 840
           TEPGLASRHLLSPVGRRQVAGHTRGPRLSLRFLGSYRTLVSLLLAFFVASLFCVGPLPCT
Sbjct: 781 TEPGLASRHLLSPVGRRQVAGHTRGPRLSLRFLGSYRTLVSLLLAFFVASLFCVGPLPCT 840

Query: 841 LLLTLGYVLYASAMTLLTERGKLHQP 866
           LLLTLGYVLYASAMTLLTERGKLHQP
Sbjct: 841 LLLTLGYVLYASAMTLLTERGKLHQP 866


>gi|102467484 sphingomyelin phosphodiesterase 4 isoform 1 [Homo
           sapiens]
          Length = 837

 Score = 1690 bits (4377), Expect = 0.0
 Identities = 837/866 (96%), Positives = 837/866 (96%), Gaps = 29/866 (3%)

Query: 1   MTTFGAVAEWRLPSLRRATLWIPQWFAKKAIFNSPLEAAMAFPHLQQPSFLLASLKADSI 60
           MTTFGAVAEWRLPSLRRATLWIPQWFAKKAIFNSPLEAAMAFPHLQQPSFLLASLKADSI
Sbjct: 1   MTTFGAVAEWRLPSLRRATLWIPQWFAKKAIFNSPLEAAMAFPHLQQPSFLLASLKADSI 60

Query: 61  NKPFAQQCQDLVKVIEDFPAKELHTIFPWLVESIFGSLDGVLVGWNLRCLQGRVNPVEYS 120
           NKPFAQQCQDLVKVIEDFPAKELHTIFPWLVESIFGSLDGVLVGWNLRCLQGRVNPVEYS
Sbjct: 61  NKPFAQQCQDLVKVIEDFPAKELHTIFPWLVESIFGSLDGVLVGWNLRCLQGRVNPVEYS 120

Query: 121 IVMEFLDPGGPMMKLVYKLQAEDYKFDFPVSYLPGPVKASIQECILPDSPLYHNKVQFTP 180
           IVMEFLDPGGPMMKLVYKLQAEDYKFDFPVSYLPGPVKASIQECILPDSPLYHNKVQFTP
Sbjct: 121 IVMEFLDPGGPMMKLVYKLQAEDYKFDFPVSYLPGPVKASIQECILPDSPLYHNKVQFTP 180

Query: 181 TGGLGLNLALNPFEYYIFFFALSLITQKPLPVSLHVRTSDCAYFILVDRYLSWFLPTEGS 240
           TGGLGLNLALNPFEYYIFFFALSLITQKPLPVSLHVRTSDCAYFILVDRYLSWFLPTEGS
Sbjct: 181 TGGLGLNLALNPFEYYIFFFALSLITQKPLPVSLHVRTSDCAYFILVDRYLSWFLPTEGS 240

Query: 241 VPPPLSSSPGGTSPSPPPRTPAIPFASYGLHHTSLLKRHISHQTSVNADPASHEIWRSET 300
           VPPPLSSSPGGTSPSPPPRTPAIPFASYGLHHTSLLKRHISHQTSVNADPASHEIWRSET
Sbjct: 241 VPPPLSSSPGGTSPSPPPRTPAIPFASYGLHHTSLLKRHISHQTSVNADPASHEIWRSET 300

Query: 301 LLQVFVEMWLHHYSLEMYQKMQSPHAKLEVLHYRLSVSSALYSPAQPSLQALHAYQESFT 360
           LLQVFVEMWLHHYSLEMYQKMQSPHAK                             ESFT
Sbjct: 301 LLQVFVEMWLHHYSLEMYQKMQSPHAK-----------------------------ESFT 331

Query: 361 PTEEHVLVVRLLLKHLHAFANSLKPEQASPSAHSHATSPLEEFKRAAVPRFVQQKLYLFL 420
           PTEEHVLVVRLLLKHLHAFANSLKPEQASPSAHSHATSPLEEFKRAAVPRFVQQKLYLFL
Sbjct: 332 PTEEHVLVVRLLLKHLHAFANSLKPEQASPSAHSHATSPLEEFKRAAVPRFVQQKLYLFL 391

Query: 421 QHCFGHWPLDASFRAVLEMWLSYLQPWRYAPDKQAPGSDSQPRCVSEKWAPFVQENLLMY 480
           QHCFGHWPLDASFRAVLEMWLSYLQPWRYAPDKQAPGSDSQPRCVSEKWAPFVQENLLMY
Sbjct: 392 QHCFGHWPLDASFRAVLEMWLSYLQPWRYAPDKQAPGSDSQPRCVSEKWAPFVQENLLMY 451

Query: 481 TKLFVGFLNRALRTDLVSPKHALMVFRVAKVFAQPNLAEMIQKGEQLFLEPELVIPHRQH 540
           TKLFVGFLNRALRTDLVSPKHALMVFRVAKVFAQPNLAEMIQKGEQLFLEPELVIPHRQH
Sbjct: 452 TKLFVGFLNRALRTDLVSPKHALMVFRVAKVFAQPNLAEMIQKGEQLFLEPELVIPHRQH 511

Query: 541 RLFTAPTFTGSFLSPWPPAVTDASFKVKSHVYSLEGQDCKYTPMFGPEARTLVLRLAQLI 600
           RLFTAPTFTGSFLSPWPPAVTDASFKVKSHVYSLEGQDCKYTPMFGPEARTLVLRLAQLI
Sbjct: 512 RLFTAPTFTGSFLSPWPPAVTDASFKVKSHVYSLEGQDCKYTPMFGPEARTLVLRLAQLI 571

Query: 601 TQAKHTAKSISDQCAESPAGHSFLSWLGFSSMDTNGSYTANDLDEMGQDSVRKTDEYLEK 660
           TQAKHTAKSISDQCAESPAGHSFLSWLGFSSMDTNGSYTANDLDEMGQDSVRKTDEYLEK
Sbjct: 572 TQAKHTAKSISDQCAESPAGHSFLSWLGFSSMDTNGSYTANDLDEMGQDSVRKTDEYLEK 631

Query: 661 ALEYLRQIFRLSEAQLRQFTLALGTTQDENGKKQLPDCIVGEDGLILTPLGRYQIINGLR 720
           ALEYLRQIFRLSEAQLRQFTLALGTTQDENGKKQLPDCIVGEDGLILTPLGRYQIINGLR
Sbjct: 632 ALEYLRQIFRLSEAQLRQFTLALGTTQDENGKKQLPDCIVGEDGLILTPLGRYQIINGLR 691

Query: 721 RFEIEYQGDPELQPIRSYEIASLVRTLFRLSSAINHRFAGQMAALCSRDDFLGSFCRYHL 780
           RFEIEYQGDPELQPIRSYEIASLVRTLFRLSSAINHRFAGQMAALCSRDDFLGSFCRYHL
Sbjct: 692 RFEIEYQGDPELQPIRSYEIASLVRTLFRLSSAINHRFAGQMAALCSRDDFLGSFCRYHL 751

Query: 781 TEPGLASRHLLSPVGRRQVAGHTRGPRLSLRFLGSYRTLVSLLLAFFVASLFCVGPLPCT 840
           TEPGLASRHLLSPVGRRQVAGHTRGPRLSLRFLGSYRTLVSLLLAFFVASLFCVGPLPCT
Sbjct: 752 TEPGLASRHLLSPVGRRQVAGHTRGPRLSLRFLGSYRTLVSLLLAFFVASLFCVGPLPCT 811

Query: 841 LLLTLGYVLYASAMTLLTERGKLHQP 866
           LLLTLGYVLYASAMTLLTERGKLHQP
Sbjct: 812 LLLTLGYVLYASAMTLLTERGKLHQP 837


>gi|160420295 hypothetical protein LOC85459 [Homo sapiens]
          Length = 2601

 Score = 38.9 bits (89), Expect = 0.021
 Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 14/105 (13%)

Query: 316  EMYQKMQSPHAKLEVLHYRLSVSSALYSPAQPSLQALHAYQESFTPTEEHVLVVRL---- 371
            E   K+ S H ++  L  RL   S L  P Q +L+AL   QE      E +++ R     
Sbjct: 1318 ESESKIFSSHLQIPQLQDRLLRISQLIQPQQDNLKAL---QEQLATQREAIILARQEARE 1374

Query: 372  -LLKHLHAFANSLKPEQASPSA------HSHATSPLEEFKRAAVP 409
             LL H   +   + PEQ   S+      HS A+ PL E +R   P
Sbjct: 1375 ELLLHQSEWEGRISPEQVDTSSLPLVPQHSFASLPLNESERNQEP 1419


>gi|149192855 HLA-B associated transcript 2-like [Homo sapiens]
          Length = 2229

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 16/54 (29%), Positives = 25/54 (46%)

Query: 235  LPTEGSVPPPLSSSPGGTSPSPPPRTPAIPFASYGLHHTSLLKRHISHQTSVNA 288
            +P+ G VP P +  P   SPS  P   A+   S   H+    K+ +  + S+ A
Sbjct: 2145 VPSGGPVPSPQTYRPSSASPSGKPSGSAVNMGSVQGHYVQQAKQRVDEKPSLGA 2198


>gi|78000158 eukaryotic translation initiation factor 2B, subunit 4
           delta isoform 2 [Homo sapiens]
          Length = 523

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 51/203 (25%), Positives = 75/203 (36%), Gaps = 26/203 (12%)

Query: 238 EGSVPPPLSSSPGGTSPSPPPRTPAIPFASYGLHHTSLLKRHISHQTSVNADPASHEIWR 297
           +G  PP  S S  G +PS   R P  P     L    L+K+    Q     D      + 
Sbjct: 122 QGGPPPKASPSTAGETPSGVKRLPEYPQVD-DLLLRRLVKKPERQQVPTRKD------YG 174

Query: 298 SETLLQVFVEMWLHHYSLEMYQKMQSPHAKLEVLHYRLSVSSALYSPAQPS----LQALH 353
           S+  L   +  +    SL  +  + S      ++   L  S  L S +       L+AL 
Sbjct: 175 SKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQ 234

Query: 354 AYQESFT--PTEEHVLVVRLLLKHLHAFANSLKPEQAS---------PSAHSHATSPLEE 402
              + +T  P EE    +   LK   +F    +P  AS             S  +S  EE
Sbjct: 235 QVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREE 294

Query: 403 FK----RAAVPRFVQQKLYLFLQ 421
                 RAA+ R+VQ+K+ L  Q
Sbjct: 295 EAKSELRAAIDRYVQEKIVLAAQ 317


>gi|78000156 eukaryotic translation initiation factor 2B, subunit 4
           delta isoform 3 [Homo sapiens]
          Length = 522

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 51/203 (25%), Positives = 75/203 (36%), Gaps = 26/203 (12%)

Query: 238 EGSVPPPLSSSPGGTSPSPPPRTPAIPFASYGLHHTSLLKRHISHQTSVNADPASHEIWR 297
           +G  PP  S S  G +PS   R P  P     L    L+K+    Q     D      + 
Sbjct: 121 QGGPPPKASPSTAGETPSGVKRLPEYPQVD-DLLLRRLVKKPERQQVPTRKD------YG 173

Query: 298 SETLLQVFVEMWLHHYSLEMYQKMQSPHAKLEVLHYRLSVSSALYSPAQPS----LQALH 353
           S+  L   +  +    SL  +  + S      ++   L  S  L S +       L+AL 
Sbjct: 174 SKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQ 233

Query: 354 AYQESFT--PTEEHVLVVRLLLKHLHAFANSLKPEQAS---------PSAHSHATSPLEE 402
              + +T  P EE    +   LK   +F    +P  AS             S  +S  EE
Sbjct: 234 QVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREE 293

Query: 403 FK----RAAVPRFVQQKLYLFLQ 421
                 RAA+ R+VQ+K+ L  Q
Sbjct: 294 EAKSELRAAIDRYVQEKIVLAAQ 316


>gi|187607323 eukaryotic translation initiation factor 2B, subunit 4
           delta isoform 1 [Homo sapiens]
          Length = 543

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 51/203 (25%), Positives = 75/203 (36%), Gaps = 26/203 (12%)

Query: 238 EGSVPPPLSSSPGGTSPSPPPRTPAIPFASYGLHHTSLLKRHISHQTSVNADPASHEIWR 297
           +G  PP  S S  G +PS   R P  P     L    L+K+    Q     D      + 
Sbjct: 142 QGGPPPKASPSTAGETPSGVKRLPEYPQVD-DLLLRRLVKKPERQQVPTRKD------YG 194

Query: 298 SETLLQVFVEMWLHHYSLEMYQKMQSPHAKLEVLHYRLSVSSALYSPAQPS----LQALH 353
           S+  L   +  +    SL  +  + S      ++   L  S  L S +       L+AL 
Sbjct: 195 SKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQ 254

Query: 354 AYQESFT--PTEEHVLVVRLLLKHLHAFANSLKPEQAS---------PSAHSHATSPLEE 402
              + +T  P EE    +   LK   +F    +P  AS             S  +S  EE
Sbjct: 255 QVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREE 314

Query: 403 FK----RAAVPRFVQQKLYLFLQ 421
                 RAA+ R+VQ+K+ L  Q
Sbjct: 315 EAKSELRAAIDRYVQEKIVLAAQ 337


>gi|23510413 sorting nexin 26 [Homo sapiens]
          Length = 1126

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 20/63 (31%), Positives = 25/63 (39%)

Query: 242 PPPLSSSPGGTSPSPPPRTPAIPFASYGLHHTSLLKRHISHQTSVNADPASHEIWRSETL 301
           PPPLS    G +P PPP+ PA   A         +    S Q      PAS   +     
Sbjct: 716 PPPLSLLRPGGAPPPPPKNPARLMALALAERAQQVAEQQSQQECGGTPPASQSPFHRSLS 775

Query: 302 LQV 304
           L+V
Sbjct: 776 LEV 778


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 12/23 (52%), Positives = 14/23 (60%)

Query: 236 PTEGSVPPPLSSSPGGTSPSPPP 258
           P+ G  PPP S +P G  P PPP
Sbjct: 354 PSRGKPPPPPSRTPAGPPPPPPP 376


>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
          Length = 2325

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 25/116 (21%)

Query: 242  PPPLSSS-----PG----GTSPS-------PPPRTPAIPFASYGLHHTSLLKRH-ISHQT 284
            PPPL ++     PG    G  P+       PPP   +IPF   G+ H ++ + H + ++ 
Sbjct: 1266 PPPLPNNSRPLTPGTVVYGPPPAGAPMVYGPPPPNFSIPFIPMGVLHCNVPEHHNLENEV 1325

Query: 285  SVNADPASH-------EIWRSETLLQVFVEM-WLHHYSLEMYQKMQSPHAKLEVLH 332
            S   D   H       E W   +  Q   EM  LHH   ++ Q+ +S   ++E LH
Sbjct: 1326 SRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELH 1381


>gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]
          Length = 641

 Score = 32.0 bits (71), Expect = 2.5
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 629 FSSMDTNGSYTANDLDEMGQDSVRKTDEYLEKALEYLRQIFRLSEAQLRQFTLALGTTQD 688
           F  +D   S T    +E+  D  R T E +EKAL   +    L +AQ+    L  G+T+ 
Sbjct: 288 FEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAK----LDKAQIHDLVLVGGSTRI 343

Query: 689 ENGKKQLPDCIVGED 703
              +K L D   G D
Sbjct: 344 PKVQKLLQDFFNGRD 358


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
           sapiens]
          Length = 1116

 Score = 32.0 bits (71), Expect = 2.5
 Identities = 18/60 (30%), Positives = 34/60 (56%), Gaps = 2/60 (3%)

Query: 641 NDLDEMGQDSVRKTDEYLEKALEYLRQIFRLSEAQLRQFTLALGTTQDENGKKQLPDCIV 700
           ND  +  QDS+RK D+ +E+  E LR+  +++    R+  LA   +   N +KQ+ + ++
Sbjct: 822 NDSSQQLQDSLRKKDDRIEELEEALRESVQITAE--REMVLAQEESARTNAEKQVEELLM 879


>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
          Length = 1088

 Score = 32.0 bits (71), Expect = 2.5
 Identities = 18/60 (30%), Positives = 34/60 (56%), Gaps = 2/60 (3%)

Query: 641 NDLDEMGQDSVRKTDEYLEKALEYLRQIFRLSEAQLRQFTLALGTTQDENGKKQLPDCIV 700
           ND  +  QDS+RK D+ +E+  E LR+  +++    R+  LA   +   N +KQ+ + ++
Sbjct: 794 NDSSQQLQDSLRKKDDRIEELEEALRESVQITAE--REMVLAQEESARTNAEKQVEELLM 851


>gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
          Length = 641

 Score = 32.0 bits (71), Expect = 2.5
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 629 FSSMDTNGSYTANDLDEMGQDSVRKTDEYLEKALEYLRQIFRLSEAQLRQFTLALGTTQD 688
           F  +D   S T    +E+  D  R T E +EKAL   +    L +AQ+    L  G+T+ 
Sbjct: 288 FEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAK----LDKAQIHDLVLVGGSTRI 343

Query: 689 ENGKKQLPDCIVGED 703
              +K L D   G D
Sbjct: 344 PKVQKLLQDFFNGRD 358


>gi|239757337 PREDICTED: hypothetical protein XP_002345251 [Homo
           sapiens]
          Length = 330

 Score = 32.0 bits (71), Expect = 2.5
 Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 3/50 (6%)

Query: 235 LPTEGS---VPPPLSSSPGGTSPSPPPRTPAIPFASYGLHHTSLLKRHIS 281
           LP  G      P L+ +PG  +PSPPP     P  S+ L   S L R +S
Sbjct: 256 LPERGGRALTTPALARTPGSLAPSPPPSPNPRPAPSFFLRAGSHLVRKVS 305


>gi|239751874 PREDICTED: hypothetical protein XP_002348034 [Homo
           sapiens]
          Length = 330

 Score = 32.0 bits (71), Expect = 2.5
 Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 3/50 (6%)

Query: 235 LPTEGS---VPPPLSSSPGGTSPSPPPRTPAIPFASYGLHHTSLLKRHIS 281
           LP  G      P L+ +PG  +PSPPP     P  S+ L   S L R +S
Sbjct: 256 LPERGGRALTTPALARTPGSLAPSPPPSPNPRPAPSFFLRAGSHLVRKVS 305


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 32.0 bits (71), Expect = 2.5
 Identities = 13/23 (56%), Positives = 13/23 (56%)

Query: 242 PPPLSSSPGGTSPSPPPRTPAIP 264
           PPPLS   GG  P PPP  P  P
Sbjct: 380 PPPLSQPTGGAPPPPPPPPPPGP 402


>gi|100913204 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11
           isoform 2 [Homo sapiens]
          Length = 856

 Score = 32.0 bits (71), Expect = 2.5
 Identities = 33/127 (25%), Positives = 51/127 (40%), Gaps = 12/127 (9%)

Query: 576 GQDCKYTPMFG-----PEARTLVLRLAQLITQAKHTAKSI--SDQCAESPAGHSFLSWL- 627
           G++ +  P +G     P A+ +VL    L+  A   A  I   DQ       H+ +  + 
Sbjct: 344 GKEARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTIT 403

Query: 628 GFSSMDTNGSYTANDLDEMGQDSVRKTDEYLEKALEYLRQIFRLSEAQLRQFTLALGTTQ 687
           G  S++ +GS       ++ Q   R       K L YL+QI  L    L +F   LG   
Sbjct: 404 GMHSVEVSGSQLCQAHSQLLQYVERYGKRLKAKNLMYLKQILYL----LEKFVAVLGGNI 459

Query: 688 DENGKKQ 694
            +N   Q
Sbjct: 460 KQNPNTQ 466


>gi|100913202 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11
           isoform 1 [Homo sapiens]
          Length = 906

 Score = 32.0 bits (71), Expect = 2.5
 Identities = 33/127 (25%), Positives = 51/127 (40%), Gaps = 12/127 (9%)

Query: 576 GQDCKYTPMFG-----PEARTLVLRLAQLITQAKHTAKSI--SDQCAESPAGHSFLSWL- 627
           G++ +  P +G     P A+ +VL    L+  A   A  I   DQ       H+ +  + 
Sbjct: 344 GKEARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTIT 403

Query: 628 GFSSMDTNGSYTANDLDEMGQDSVRKTDEYLEKALEYLRQIFRLSEAQLRQFTLALGTTQ 687
           G  S++ +GS       ++ Q   R       K L YL+QI  L    L +F   LG   
Sbjct: 404 GMHSVEVSGSQLCQAHSQLLQYVERYGKRLKAKNLMYLKQILYL----LEKFVAVLGGNI 459

Query: 688 DENGKKQ 694
            +N   Q
Sbjct: 460 KQNPNTQ 466


>gi|132566527 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11
           isoform 3 [Homo sapiens]
          Length = 970

 Score = 32.0 bits (71), Expect = 2.5
 Identities = 33/127 (25%), Positives = 51/127 (40%), Gaps = 12/127 (9%)

Query: 576 GQDCKYTPMFG-----PEARTLVLRLAQLITQAKHTAKSI--SDQCAESPAGHSFLSWL- 627
           G++ +  P +G     P A+ +VL    L+  A   A  I   DQ       H+ +  + 
Sbjct: 344 GKEARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTIT 403

Query: 628 GFSSMDTNGSYTANDLDEMGQDSVRKTDEYLEKALEYLRQIFRLSEAQLRQFTLALGTTQ 687
           G  S++ +GS       ++ Q   R       K L YL+QI  L    L +F   LG   
Sbjct: 404 GMHSVEVSGSQLCQAHSQLLQYVERYGKRLKAKNLMYLKQILYL----LEKFVAVLGGNI 459

Query: 688 DENGKKQ 694
            +N   Q
Sbjct: 460 KQNPNTQ 466


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 31.6 bits (70), Expect = 3.3
 Identities = 14/30 (46%), Positives = 15/30 (50%)

Query: 235 LPTEGSVPPPLSSSPGGTSPSPPPRTPAIP 264
           LP E  +PPP    PGG    PPP  P  P
Sbjct: 698 LPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 727


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 31.6 bits (70), Expect = 3.3
 Identities = 14/30 (46%), Positives = 15/30 (50%)

Query: 235 LPTEGSVPPPLSSSPGGTSPSPPPRTPAIP 264
           LP E  +PPP    PGG    PPP  P  P
Sbjct: 707 LPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 736


>gi|55741571 leucine rich repeat and fibronectin type III domain
           containing 2 [Homo sapiens]
          Length = 789

 Score = 31.6 bits (70), Expect = 3.3
 Identities = 12/23 (52%), Positives = 15/23 (65%)

Query: 237 TEGSVPPPLSSSPGGTSPSPPPR 259
           T G+ PPP SS+P G  P  PP+
Sbjct: 579 TNGAQPPPPSSAPAGAPPQGPPK 601


>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
          Length = 1303

 Score = 31.6 bits (70), Expect = 3.3
 Identities = 18/38 (47%), Positives = 22/38 (57%), Gaps = 3/38 (7%)

Query: 236 PTEGSVPPPLSSSPGGTSPSPPPRTP-AIPFASYGLHH 272
           P   S PPP  S P  ++PSPPP +P A P   + LHH
Sbjct: 11  PPSESPPPP--SPPPPSTPSPPPCSPDARPATPHLLHH 46



 Score = 31.2 bits (69), Expect = 4.3
 Identities = 15/26 (57%), Positives = 17/26 (65%), Gaps = 1/26 (3%)

Query: 239 GSVPPPLSSSPGGTSPSPPPRTPAIP 264
           G+ PPP S SP   SP PPP TP+ P
Sbjct: 6   GTPPPPPSESPPPPSP-PPPSTPSPP 30


>gi|38505213 YTH domain containing 2 [Homo sapiens]
          Length = 1430

 Score = 31.6 bits (70), Expect = 3.3
 Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 9/84 (10%)

Query: 236  PTEGSVPPPLSSSPGGTSPSPPPRTPAIPFASYGLHHTSLLKRHISHQTSVNADPASHE- 294
            P+  + P P SS  G  SPSP P  P   F    +  ++L    IS Q  + +   S+E 
Sbjct: 1262 PSPCASPSPPSSGKGSKSPSPRPNMPVRYFI---MKSSNLRNLEISQQKGIWSTTPSNER 1318

Query: 295  -----IWRSETLLQVFVEMWLHHY 313
                  W S  +  VF      H+
Sbjct: 1319 KLNRAFWESSIVYLVFSVQGSGHF 1342


>gi|148236531 hypothetical protein LOC339779 [Homo sapiens]
          Length = 412

 Score = 31.6 bits (70), Expect = 3.3
 Identities = 35/129 (27%), Positives = 57/129 (44%), Gaps = 21/129 (16%)

Query: 240 SVPPPLSSSPG--------GTSPSPPPRTPAIPFASYGLHHTSLLKRHISHQTSVNADPA 291
           S PPP S SPG         +  +P P +P++P +    H     + ++S      + P+
Sbjct: 60  SSPPPASPSPGFQFGSCDSNSDFAPHPYSPSLPSSPTFFH-----QNYLSLPRPRASSPS 114

Query: 292 SHEIWRSETLLQVFVEMWLHHYSLEMYQKMQSPHAKLEVLHYRLSVSSALYSPA-QPSLQ 350
           +H ++ S  L   F      + SL  +   QSP +  E LH     SS L SP   P   
Sbjct: 115 NHWLYPSPPLTPSFSPSQPQNSSLP-HSPCQSP-SHPEELH-----SSTLTSPGPSPPSH 167

Query: 351 ALHAYQESF 359
            LH+ ++++
Sbjct: 168 RLHSNRQTW 176


>gi|12232415 hypothetical protein LOC64762 [Homo sapiens]
          Length = 875

 Score = 31.2 bits (69), Expect = 4.3
 Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 23/95 (24%)

Query: 243 PPLSSSPGGTSPSPPPRT------------PAIPFASYGLHH-TSLLKRHISHQTSVNAD 289
           PP S+ P  TSPS PPRT            P + + S GLH+  +    + S  T V+  
Sbjct: 536 PPRSAKPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCY 595

Query: 290 PASHEIWRSETLLQVFVE----------MWLHHYS 314
           P +     S  L   F             W +HYS
Sbjct: 596 PCNRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYS 630


>gi|45580719 osteoclast-associated receptor isoform 1 [Homo sapiens]
          Length = 286

 Score = 31.2 bits (69), Expect = 4.3
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 3/62 (4%)

Query: 231 LSWFLPTEGSVPPPLSSSPGGTSPSPPPRTPAIPFASY-GLHHTSLLKRHISHQTSVNAD 289
           +SW    EG    P SS+PG  +P PPP  P     S        L+ + +  QT  + D
Sbjct: 219 ISW--EGEGPEARPASSAPGMQAPGPPPSDPGAQAPSLSSFRPRGLVLQPLLPQTQDSWD 276

Query: 290 PA 291
           PA
Sbjct: 277 PA 278


>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
          Length = 1073

 Score = 31.2 bits (69), Expect = 4.3
 Identities = 35/133 (26%), Positives = 53/133 (39%), Gaps = 26/133 (19%)

Query: 242 PPPLSSSPGGTSPSPP--------PRTPAIPFASYGLHHTSLLKRHISHQTSVNADPASH 293
           PPP +SS  G  P PP         +  A P A  G   T + K+     TSV     S 
Sbjct: 67  PPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGG---TQMKKKSGFQITSVTPAQISA 123

Query: 294 EIWRSETLLQVFVEMWLHHYSLEMYQKMQSPH----AKLEVLHYRLSVSSALYSPAQPSL 349
            I  + ++ +            E Y  +   H    +  E+L   LS ++ L  P + S 
Sbjct: 124 SISSNNSIAE----------DTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSS 173

Query: 350 -QALHAYQESFTP 361
            + L+ +QE+ TP
Sbjct: 174 EETLNNFQEAETP 186


>gi|54112420 Cas-Br-M (murine) ecotropic retroviral transforming
           sequence b [Homo sapiens]
          Length = 982

 Score = 30.8 bits (68), Expect = 5.7
 Identities = 22/57 (38%), Positives = 24/57 (42%), Gaps = 13/57 (22%)

Query: 242 PPPLSSSPGGTSPSPPPRTPAIPFASYGLHHTSLLKRHISHQTSVNA--DPASHEIW 296
           PPPL   P    P PP R P IP         + L RHI H  SV +   P   E W
Sbjct: 548 PPPLRDPP----PPPPERPPPIP-------PDNRLSRHIHHVESVPSRDPPMPLEAW 593


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,741,878
Number of Sequences: 37866
Number of extensions: 1759710
Number of successful extensions: 8268
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 8011
Number of HSP's gapped (non-prelim): 270
length of query: 866
length of database: 18,247,518
effective HSP length: 111
effective length of query: 755
effective length of database: 14,044,392
effective search space: 10603515960
effective search space used: 10603515960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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