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Search of human proteins with 102467242
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|102467242 inner centromere protein antigens 135/155kDa
isoform 2 [Homo sapiens]
(914 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 1794 0.0
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 1788 0.0
gi|148746195 trichohyalin [Homo sapiens] 141 3e-33
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 132 2e-30
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 131 3e-30
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 129 2e-29
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 128 2e-29
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 127 6e-29
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 120 6e-27
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 120 6e-27
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 120 6e-27
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 120 6e-27
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 118 2e-26
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 115 2e-25
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 115 2e-25
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 114 5e-25
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 112 2e-24
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 111 3e-24
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 110 8e-24
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 110 8e-24
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 110 8e-24
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 107 7e-23
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 103 6e-22
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 102 2e-21
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 102 2e-21
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 102 2e-21
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 102 2e-21
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 102 2e-21
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 102 2e-21
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 102 2e-21
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 1794 bits (4646), Expect = 0.0
Identities = 914/914 (100%), Positives = 914/914 (100%)
Query: 1 MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTP 60
MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTP
Sbjct: 1 MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTP 60
Query: 61 SQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSV 120
SQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSV
Sbjct: 61 SQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSV 120
Query: 121 LRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAE 180
LRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAE
Sbjct: 121 LRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAE 180
Query: 181 QHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATP 240
QHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATP
Sbjct: 181 QHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATP 240
Query: 241 QDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILPDNFSTPTGSRTDS 300
QDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILPDNFSTPTGSRTDS
Sbjct: 241 QDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILPDNFSTPTGSRTDS 300
Query: 301 QSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLE 360
QSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLE
Sbjct: 301 QSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLE 360
Query: 361 RLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAAS 420
RLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAAS
Sbjct: 361 RLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAAS 420
Query: 421 SPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPS 480
SPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPS
Sbjct: 421 SPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPS 480
Query: 481 SPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLEN 540
SPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLEN
Sbjct: 481 SPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLEN 540
Query: 541 LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFA 600
LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFA
Sbjct: 541 LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFA 600
Query: 601 QIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELL 660
QIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELL
Sbjct: 601 QIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELL 660
Query: 661 QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQER 720
QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQER
Sbjct: 661 QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQER 720
Query: 721 RREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAA 780
RREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAA
Sbjct: 721 RREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAA 780
Query: 781 GASKALNVTVDVQSPACTSYQMTPQGHRAPPKINPDNYGMDLNSDDSTDDEAHPRKPIPT 840
GASKALNVTVDVQSPACTSYQMTPQGHRAPPKINPDNYGMDLNSDDSTDDEAHPRKPIPT
Sbjct: 781 GASKALNVTVDVQSPACTSYQMTPQGHRAPPKINPDNYGMDLNSDDSTDDEAHPRKPIPT 840
Query: 841 WARGTPLSQAIIHQYYHPPNLLELFGTILPLDLEDIFKKSKPRYHKRTSSAVWNSPPLQG 900
WARGTPLSQAIIHQYYHPPNLLELFGTILPLDLEDIFKKSKPRYHKRTSSAVWNSPPLQG
Sbjct: 841 WARGTPLSQAIIHQYYHPPNLLELFGTILPLDLEDIFKKSKPRYHKRTSSAVWNSPPLQG 900
Query: 901 ARVPSSLAYSLKKH 914
ARVPSSLAYSLKKH
Sbjct: 901 ARVPSSLAYSLKKH 914
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 1788 bits (4631), Expect = 0.0
Identities = 914/918 (99%), Positives = 914/918 (99%), Gaps = 4/918 (0%)
Query: 1 MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTP 60
MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTP
Sbjct: 1 MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTP 60
Query: 61 SQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSV 120
SQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSV
Sbjct: 61 SQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSV 120
Query: 121 LRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAE 180
LRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAE
Sbjct: 121 LRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAE 180
Query: 181 QHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATP 240
QHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATP
Sbjct: 181 QHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATP 240
Query: 241 QDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILPDNFSTPTGSRTDS 300
QDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILPDNFSTPTGSRTDS
Sbjct: 241 QDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILPDNFSTPTGSRTDS 300
Query: 301 QSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLE 360
QSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLE
Sbjct: 301 QSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLE 360
Query: 361 RLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAAS 420
RLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAAS
Sbjct: 361 RLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAAS 420
Query: 421 SPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPS 480
SPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPS
Sbjct: 421 SPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPS 480
Query: 481 SPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPK----EKERQ 536
SPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPK EKERQ
Sbjct: 481 SPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQ 540
Query: 537 RLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIE 596
RLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIE
Sbjct: 541 RLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIE 600
Query: 597 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 656
QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH
Sbjct: 601 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 660
Query: 657 QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLA 716
QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLA
Sbjct: 661 QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLA 720
Query: 717 EQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 776
EQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA
Sbjct: 721 EQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 780
Query: 777 KEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKINPDNYGMDLNSDDSTDDEAHPRK 836
KEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKINPDNYGMDLNSDDSTDDEAHPRK
Sbjct: 781 KEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKINPDNYGMDLNSDDSTDDEAHPRK 840
Query: 837 PIPTWARGTPLSQAIIHQYYHPPNLLELFGTILPLDLEDIFKKSKPRYHKRTSSAVWNSP 896
PIPTWARGTPLSQAIIHQYYHPPNLLELFGTILPLDLEDIFKKSKPRYHKRTSSAVWNSP
Sbjct: 841 PIPTWARGTPLSQAIIHQYYHPPNLLELFGTILPLDLEDIFKKSKPRYHKRTSSAVWNSP 900
Query: 897 PLQGARVPSSLAYSLKKH 914
PLQGARVPSSLAYSLKKH
Sbjct: 901 PLQGARVPSSLAYSLKKH 918
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 141 bits (355), Expect = 3e-33
Identities = 100/345 (28%), Positives = 196/345 (56%), Gaps = 32/345 (9%)
Query: 442 EPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQR 501
EP Q R+KR ++ EEQ + E L+ + ++ R + + +R
Sbjct: 132 EPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDE-----ELWRQRQEWQEREER 186
Query: 502 NQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRK--EEAEQLRR------- 552
A ++S T D ++ R+ L LRRK EE +Q RR
Sbjct: 187 R--------AEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVF 238
Query: 553 QKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEE 612
Q+ EE + R+ E V K EE+L++ R+R Q +EE+ +++E++ + + + E+ +++
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 613 RLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLR 672
RL E+ ++ ++ E RR+Q+EE R + ++++EERR Q+L ++++E +++LR
Sbjct: 299 RLRREQQLRR------KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLR 352
Query: 673 KAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERE 732
+ E +R +Q +E+ E+ R +Q RREQ+ R +++ +E+QL +++ R +++L+ E++
Sbjct: 353 REQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 412
Query: 733 LQEREKALRLQKEQLQRELEEKK--KKEEQQRLAERQLQEEQEKK 775
L+ RE+ LR +++QL+RE EE++ +K EQ+R +R +E++E++
Sbjct: 413 LR-REQQLR-REQQLRREQEEERHEQKHEQERREQRLKREQEERR 455
Score = 140 bits (353), Expect = 5e-33
Identities = 91/266 (34%), Positives = 171/266 (64%), Gaps = 24/266 (9%)
Query: 531 KEKERQRLENLRRKEEAE----QLRRQKVEEDKRRRLE-EVKLKREERLRKVLQARERVE 585
+E+E +R + LRR++E E QLRR++ EE + ++L E +L+RE++LR+ Q R R +
Sbjct: 341 REQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLR-REQ 399
Query: 586 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 645
Q++ E++ + EQ Q+ + + +E++L E+ +++ K +E +R + E+ R
Sbjct: 400 QLRREQQLRREQ---QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRD 456
Query: 646 WLQQEEEERRHQELLQK---KKEEEQERLRKAAEAKRLAEQREQERREQE--RREQERRE 700
WL++EEE RH++ +K K+++E+ER + + + + +QERREQ+ R ++ERRE
Sbjct: 457 WLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERRE 516
Query: 701 Q--ERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK--EQLQRELEEKK- 755
Q +R+E+E R Q+R +EQ+ RREQE + + +E EK L ++ ++L+RE EE++
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Query: 756 ---KKEEQQRLAERQLQEEQEKKAKE 778
K+EE++R +++L+ EQE++ ++
Sbjct: 577 QLLKREEERR--QQRLKREQEERLEQ 600
Score = 140 bits (353), Expect = 5e-33
Identities = 106/361 (29%), Positives = 202/361 (55%), Gaps = 24/361 (6%)
Query: 429 QQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLE-DEELQPPRSKTPSSPCPASK 487
+Q+ + +Q + RE Q RR++ ++ +L EQ L +++L+ + +
Sbjct: 348 EQQLRREQEEERRE--QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405
Query: 488 VVRPLRTFLHTVQ--RNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKE 545
+R + Q R Q L R K +R K ++ +R + L+R+E
Sbjct: 406 QLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR---EQRLKREQEERRDWLKREE 462
Query: 546 EAE----QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQ 601
E E + R+Q+++ D+ E LK EE R+ Q R R +Q++ E++++ EQ+ +
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQER-REQQLRREQEERREQRLKR 521
Query: 602 IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQE--EEARRLRWLQQEEEERRHQEL 659
+E E+ ++RL E+ ++ ++ E++ R +++ E+ RR + L++E+EERR Q L
Sbjct: 522 QEE--EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ-L 578
Query: 660 LQKKKEEEQERLRKAAEAK--RLAEQREQERREQERREQERREQERREQERREQERQLAE 717
L++++E Q+RL++ E + + ++ E ER EQE R ++R ++E E+ERR+Q + E
Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE 638
Query: 718 QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777
QE RR+Q Q RE QER + RL++E+ + LE++ K+E ++ E++L EE++++A+
Sbjct: 639 QEERRQQ---QLRREQQERREQ-RLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR 694
Query: 778 E 778
E
Sbjct: 695 E 695
Score = 138 bits (348), Expect = 2e-32
Identities = 106/398 (26%), Positives = 220/398 (55%), Gaps = 43/398 (10%)
Query: 423 ETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRS-KTPSS 481
E +++ + +Q D R + R+++ +++ EE+ E+E+LQ + +T
Sbjct: 150 EGEEQSEKQERLEQRDRQRRDEELWRQRQEWQER-----EERRAEEEQLQSCKGHETEEF 204
Query: 482 PCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVM----KSFIKRNTPLRMDPK---EKE 534
P R L + + R K + KR T LR + + E+E
Sbjct: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE 264
Query: 535 RQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV----KLKREERLRKVLQARERVEQ---- 586
QR L+ EE EQLR+ + +E +R R EE +L+RE++LR+ + R +Q
Sbjct: 265 PQRQRELQ--EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERR 322
Query: 587 -MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAK-KMEEVEARRKQ------- 637
+E +++Q E++ Q+ + E+ +E++L E+ +++ + + E+ E RR+Q
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
Query: 638 ---EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR-LAEQREQERREQER 693
E++ RR + L++E++ RR Q+L ++++ +++LR+ + +R E+R +++ EQER
Sbjct: 383 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQER 442
Query: 694 REQ--ERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQREL 751
REQ +R ++ERR+ +RE+E + EQERR++Q L+ ++E + RE+ L+L++E+ + +
Sbjct: 443 REQRLKREQEERRDWLKREEETERHEQERRKQQ--LKRDQEEERRERWLKLEEEERREQQ 500
Query: 752 EEKK---KKEEQQRLAERQLQEEQEKKAKEAAGASKAL 786
E ++ ++E+++R +R ++E+E++ ++ + + L
Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL 538
Score = 138 bits (348), Expect = 2e-32
Identities = 102/361 (28%), Positives = 197/361 (54%), Gaps = 35/361 (9%)
Query: 441 REPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQ 500
RE Q RR+R + E ++E + L+ K + ++ L ++
Sbjct: 223 REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282
Query: 501 RNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKR 560
R ++ + + ++R LR +E+ R++ E R ++E + + ++ E+ R
Sbjct: 283 RQELRRERQEEEQQQQR--LRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLR 340
Query: 561 RRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK 620
R EE +RE++LR+ + R +Q++ E+++ E++ Q+ + + +E++L E+
Sbjct: 341 REQEE---RREQQLRREQEEERREQQLRREQEE--ERREQQLRREQQLRREQQLRREQQL 395
Query: 621 KKAAAKKMEEVEARRKQ---EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEA 677
++ + E+ R +Q E++ RR + L++E+EE RH++ + ++E ++RL++ E
Sbjct: 396 RREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQ--KHEQERREQRLKREQEE 453
Query: 678 KR--LAEQREQERREQERREQERR---EQERR-------EQERREQERQLAEQERRREQE 725
+R L + E ER EQERR+Q+ + E+ERR E+ERREQ+ + +Q RR ++E
Sbjct: 454 RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE 513
Query: 726 RLQAERELQEREKAL--RLQKE-QLQRELEEKK----KKEEQQRL----AERQLQEEQEK 774
R + + QE E+ L RL+ E QL+RE EE++ K+EE++RL E++L+ EQE+
Sbjct: 514 RREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE 573
Query: 775 K 775
+
Sbjct: 574 R 574
Score = 138 bits (348), Expect = 2e-32
Identities = 114/391 (29%), Positives = 201/391 (51%), Gaps = 58/391 (14%)
Query: 429 QQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKV 488
Q+E + +Q + RE Q RR++ ++ +L EQ E E Q R + +
Sbjct: 310 QEEERREQQEERRE--QQERREQQEERREQQLRREQE-ERREQQLRREQEEE------RR 360
Query: 489 VRPLRTFLHTVQRNQMLMTPTSAPRSVM---KSFIKRNTPLRMDPKEKERQRLENLRRKE 545
+ LR +R Q L R + ++R LR + + + Q+L ++
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 546 EAEQLRRQKVEE------DKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKF 599
+QLRR++ EE ++ RR + +K ++EER R L+ E E+ ++E++KQ
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEER-RDWLKREEETERHEQERRKQ----- 474
Query: 600 AQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL 659
Q+ E+ + ER + + +++ ++ E + RR+QEE R R +QEEEER Q L
Sbjct: 475 -QLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEER-REQRLKRQEEEERLQQRL 532
Query: 660 -----LQKKKEEEQERLRKAAEAKRLAEQREQER--REQERREQE--RREQERREQE-RR 709
L++++EE +E+L K E KRL ++R ++R REQE R + +RE+ERR+Q +R
Sbjct: 533 RSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
Query: 710 EQERQLAEQERRREQERLQAER----------------------ELQEREKALRLQKEQL 747
EQE +L ++ +R E ERL+ E E QE + +L++EQ
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Query: 748 QRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
+R + K++EE++RL +R +E +E++ ++
Sbjct: 653 ERREQRLKREEEEERLEQRLKREHEEERREQ 683
Score = 130 bits (327), Expect = 6e-30
Identities = 110/394 (27%), Positives = 198/394 (50%), Gaps = 45/394 (11%)
Query: 429 QQEAKTDQADGPREPPQSARRKRSYKQAVSELDE--EQHLEDEELQPPRSKTPSSPCPAS 486
Q+E + + E + +R RS +Q E +E EQ L+ EE + +
Sbjct: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE 570
Query: 487 KVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRL-------- 538
+ R + +R Q + R ++ +KR R++ +E+ QRL
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEER--LEQRLKREEVERLEQEERREQRLKREEPEEE 628
Query: 539 --ENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE-------RLRKVLQARERVEQMKE 589
+ L + EE E+ R+Q++ +++ R E+ +LKREE RL++ + R +++ E
Sbjct: 629 RRQQLLKSEEQEERRQQQLRREQQERREQ-RLKREEEEERLEQRLKREHEEERREQELAE 687
Query: 590 EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR----LR 645
E+++Q ++ K + E ++K + +K E R++QEE+ RR L+
Sbjct: 688 EEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQ 747
Query: 646 W-------LQQEEEERRHQELLQKKKEEEQERLRKAAEAK-RLAEQREQERREQERREQE 697
W QQ+EEE+R Q + EE+ ER R+ A+ L EQRE++ R +ER+++E
Sbjct: 748 WQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQRE 807
Query: 698 RR---EQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQ--LQRELE 752
+R E+E +EQ RR++ +ER +E + L+ E +LQ RE+A +LQ+E+ LQ + E
Sbjct: 808 QRFLPEEEEKEQRRRQR------REREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQE 861
Query: 753 EKKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 786
++ +E+++ R EE+ K+ + A AL
Sbjct: 862 RRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPAL 895
Score = 129 bits (324), Expect = 1e-29
Identities = 101/353 (28%), Positives = 192/353 (54%), Gaps = 48/353 (13%)
Query: 429 QQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKV 488
Q+ + +Q E Q RR+ +Q E D + EDE+L R +
Sbjct: 1586 QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFR-EDEQLLQEREEQQ--------- 1635
Query: 489 VRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAE 548
LH +R++ + R +R LR D K R+ E L ++ E +
Sbjct: 1636 -------LHRQERDRKFLEEEPQLRRQ-----EREQQLRHDRDRKFREE-EQLLQEGEEQ 1682
Query: 549 QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEK 608
QLRRQ E D++ R EE +L+R+ER RK LQ +++ +++++E+KF + ++ ++
Sbjct: 1683 QLRRQ--ERDRKFREEEQQLRRQERERKFLQEEQQL------RRQELERKFREEEQLRQE 1734
Query: 609 AKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ 668
++E+L ++ +K +EE + R ++EE+ L+++E +R+ +E Q ++E E+
Sbjct: 1735 TEQEQLRRQERYRKI----LEEEQLRPEREEQQ-----LRRQERDRKFREEEQLRQEREE 1785
Query: 669 ERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER-QLAEQERRREQER- 726
++LR ++ RE+E+ QER EQ+ R Q+R + R E+E+ QL EQE+R QER
Sbjct: 1786 QQLRSQESDRKF---REEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERD 1842
Query: 727 --LQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777
+AE + +EK+ R ++++L +E E+K+++E +++L E ++ +Q+++ +
Sbjct: 1843 RQYRAEEQFATQEKS-RREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQR 1894
Score = 127 bits (319), Expect = 5e-29
Identities = 108/376 (28%), Positives = 199/376 (52%), Gaps = 37/376 (9%)
Query: 429 QQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLE--DEELQPPRSKTPSSPCPAS 486
+Q+ + +Q + + ++ R +Q E +EE+H + ++E + R K
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEE-RRD 456
Query: 487 KVVRPLRTFLHTVQRN-QMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKE 545
+ R T H +R Q L R + ++K R + +E+ Q+L + +
Sbjct: 457 WLKREEETERHEQERRKQQLKRDQEEERR--ERWLKLEEEERREQQERREQQLRREQEER 514
Query: 546 EAEQLRRQKVEEDKRRRL---EEVKLKREERLRKVLQARE--RVEQMKEEK--KKQIEQK 598
++L+RQ+ EE ++RL ++++ ++EER ++L+ E R+EQ + E+ K++ E++
Sbjct: 515 REQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEER 574
Query: 599 FAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQE 658
Q+ ++ E+ +++RL E+ ++ K EEVE R ++EE R R ++E EE R Q+
Sbjct: 575 RDQLLKREEERRQQRLKREQEERLEQRLKREEVE--RLEQEERREQRLKREEPEEERRQQ 632
Query: 659 LLQKKKEEEQERLRKAAEAKRLAEQREQE-RREQERREQERREQERREQERREQERQLAE 717
LL K EEQE R+ + E+REQ +RE+E E+R + E+ERREQE E
Sbjct: 633 LL---KSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE 689
Query: 718 QERRRE---------QERLQAERELQEREKALRLQKEQLQR---ELEEKKKKEE------ 759
QE+ RE Q +L++E + ++ + R +K++ QR E EEK+++ E
Sbjct: 690 QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQ 749
Query: 760 QQRLAERQLQEEQEKK 775
++ A RQ QEE++++
Sbjct: 750 EEERAHRQQQEEEQRR 765
Score = 124 bits (312), Expect = 3e-28
Identities = 112/402 (27%), Positives = 201/402 (50%), Gaps = 77/402 (19%)
Query: 441 REPPQSARRKRSYKQAVSELDEEQHLEDEELQPP-RSKTPSSPCPASKVVRPLRTFLHTV 499
RE Q R++R K L+EEQ L +E R + S P K + + LH
Sbjct: 1473 REEQQLHRQERDRKF----LEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQ-LHRQ 1527
Query: 500 QRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDK 559
QR + + R +R R D K R+ E LR++ E +QL RQ E D+
Sbjct: 1528 QRQRKFLQEEQQLRRQ-----ERGQQRRQDRDRKFREE-EQLRQEREEQQLSRQ--ERDR 1579
Query: 560 RRRLEEVKLKREERLRKVLQARE--RVEQMKEEKKKQIEQKFAQIDEKTEKAKEERL--- 614
+ RLEE K++R+E+ RK ++ + R ++ +++ +++ ++KF + ++ ++ +E++L
Sbjct: 1580 KFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQ 1639
Query: 615 -------------------------------AEEKAKKKAAAKKMEEVEARRKQEEEARR 643
EE+ ++ +++ E RK EE ++
Sbjct: 1640 ERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQ 1699
Query: 644 LRWLQ------QEEEERRHQELLQKKKEEE-------------QERLRKAAEAKRLAEQR 684
LR + QEE++ R QEL +K +EEE QER RK E ++L +R
Sbjct: 1700 LRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPER 1759
Query: 685 EQERREQERREQERREQERREQERREQERQLAEQERR-REQERLQAERE-----LQEREK 738
E+++ ++ R+++ RE+E+ QER EQ+ + E +R+ RE+E+L+ ERE Q+R+
Sbjct: 1760 EEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDG 1819
Query: 739 ALRLQKEQLQRELEEKKKKEEQQR--LAERQLQEEQEKKAKE 778
R ++EQLQ E +E++ ++E+ R AE Q +++ + +E
Sbjct: 1820 KYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREE 1861
Score = 124 bits (311), Expect = 4e-28
Identities = 114/403 (28%), Positives = 208/403 (51%), Gaps = 57/403 (14%)
Query: 429 QQEAKTD--QADGPREPPQSARRKRSYKQAVSELDEEQ--HLEDEELQPPRSKTPSSPCP 484
+QE + D + + E + RRK+ K+ E E+ LE+EE + + +
Sbjct: 450 EQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR 509
Query: 485 ASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRR- 543
+ R R L + + L + + + + +R L K +E +RLE RR
Sbjct: 510 EQEERREQR--LKRQEEEERLQQRLRSEQQLRREQEERREQLL---KREEEKRLEQERRE 564
Query: 544 ---KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFA 600
K E E+ R Q ++ ++ RR + +K ++EERL + L+ RE VE++++E++++ K
Sbjct: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK-REEVERLEQEERREQRLKRE 623
Query: 601 QIDE-KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL--RWLQQEEEERRHQ 657
+ +E + ++ + EE+ +++ ++ E E R K+EEE RL R ++ EEERR Q
Sbjct: 624 EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683
Query: 658 ELLQKKKEEEQERLRK--------------AAEAKRLAEQREQE---RREQERREQERRE 700
EL ++++E+ +ER++ A ++K + R+QE RR+++ ++ RRE
Sbjct: 684 ELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRE 743
Query: 701 QERREQERREQERQLAEQERRRE--------------QERLQAERELQE-REKALRLQKE 745
E + QE RQ E+E+RR+ ++RL A L+E RE+ LR ++
Sbjct: 744 SELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER 803
Query: 746 QL--QRELEEKKKKEE---QQRLAERQLQ---EEQEKKAKEAA 780
Q QR L E+++KE+ Q+R E++LQ EE++ + +E A
Sbjct: 804 QQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERA 846
Score = 124 bits (311), Expect = 4e-28
Identities = 108/381 (28%), Positives = 198/381 (51%), Gaps = 44/381 (11%)
Query: 429 QQEAKTDQADGPREPPQSARRKRSYKQAVSELD-----EEQHLEDEELQPPRSKTPSSPC 483
Q+EAK +E Q R +R K+ E D EEQ L++ E QP R +
Sbjct: 1304 QKEAKRRDRKS-QEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKF 1362
Query: 484 PASKVVRPL--RTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENL 541
++ R FL QR + + + F+K LR +E++ ++ +
Sbjct: 1363 REEELRHQEQGRKFLEEEQRLRR--------QERERKFLKEEQQLRCQEREQQLRQDRDR 1414
Query: 542 RRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQ 601
+ +EE +QL RQ E D++ R EE +++R+ER RK L+ +++ Q + K ++ EQ +
Sbjct: 1415 KFREEEQQLSRQ--ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472
Query: 602 IDE----KTEKAK-----EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ---- 648
+E + E+ + E++L ++ +K +++ E RK EE ++L Q
Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRK 1532
Query: 649 --QEEEERRHQELLQKKKEE------EQERLRKAAEAKRLAEQREQERREQERREQERRE 700
QEE++ R QE Q+++++ E+E+LR+ E ++L+ Q + E ++ R+E
Sbjct: 1533 FLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQE 1592
Query: 701 QERREQERREQ-ERQLAEQERRREQERLQAERE--LQEREKALRLQKEQLQRELEEKKKK 757
QER+ E +Q RQ +Q+ R+E++R E E LQERE+ ++E+ ++ LEE+ +
Sbjct: 1593 QERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQL 1652
Query: 758 EEQQRLAERQLQEEQEKKAKE 778
Q+R E+QL+ ++++K +E
Sbjct: 1653 RRQER--EQQLRHDRDRKFRE 1671
Score = 122 bits (307), Expect = 1e-27
Identities = 94/279 (33%), Positives = 163/279 (58%), Gaps = 33/279 (11%)
Query: 521 KRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQA 580
+R L P +E+ R E +EE E+L+R+ E +KRRR E+ + REE Q
Sbjct: 884 RRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE--EREKRRRQEQERQYREEE-----QL 936
Query: 581 RERVEQM----KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRK 636
++ EQ+ +E++++Q ++ + D+K ++ +E+ L EE K++ ++ + E
Sbjct: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEEL 996
Query: 637 QEEEARRLRWLQQEEEERRHQELLQ--KKKEE---EQERLRKAAEAKRLAEQREQERREQ 691
Q+EE + LR +E E+RR QE + +KK+E E+E+L + KR ++RE++ RE+
Sbjct: 997 QQEEEQLLR---EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE 1053
Query: 692 ERREQERRE---QERREQERREQERQLA-EQERRREQERLQAE----RELQEREKALRLQ 743
E +QE + +ER + R+E ERQ E+E ++E+E+L E R QERE+ R +
Sbjct: 1054 EELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCR-E 1112
Query: 744 KEQLQRE----LEEKKKKEEQQRLAERQLQEEQEKKAKE 778
+E+LQ+E L E+++K +Q L ERQ +EE+E + +E
Sbjct: 1113 EEELQQEEEQLLREEREKRRRQEL-ERQYREEEEVQQEE 1150
Score = 122 bits (305), Expect = 2e-27
Identities = 116/403 (28%), Positives = 192/403 (47%), Gaps = 79/403 (19%)
Query: 429 QQEAKTDQADGPREPPQSARRKRSYKQAVSEL---DEEQHLEDEELQPPRSKTPSSPCPA 485
+QE + DQ E + R KR ++ + + +E + LE EE + R K
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLK-------- 621
Query: 486 SKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKE 545
R +R Q+L + R R LR + +E+ QRL +R+E
Sbjct: 622 -------REEPEEERRQQLLKSEEQEER--------RQQQLRREQQERREQRL---KREE 663
Query: 546 EAEQL-RRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQ-KFAQID 603
E E+L +R K E ++ RR +E+ + +E+ R+ +++R Q + E + Q K
Sbjct: 664 EEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRP 723
Query: 604 EKTEKAKEERLAEEKAKKKAAAKKMEEVEA--RRKQEEEARR---LRWLQQEEEERRHQE 658
K E + + EEK +++ + + +E E R++QEEE RR +W +E+ ER Q
Sbjct: 724 RKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR 783
Query: 659 LLQKKKEEEQERLRKAAEAKRLAEQR---EQERREQERREQERREQE-----------RR 704
L + EQ + AE ++ EQR E+E +EQ RR++ RE+E RR
Sbjct: 784 LSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRR 843
Query: 705 E---------------QERREQERQ--------LAEQERRREQERLQAERELQER----E 737
E QERR + Q E+ER+R + L A+ LQE+ +
Sbjct: 844 ERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQ 903
Query: 738 KALRLQKEQLQRELEEKKKKEEQQR--LAERQLQEEQEKKAKE 778
+ L+ ++E+LQRE EK++++EQ+R E QLQ+E+E+ +E
Sbjct: 904 QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946
Score = 120 bits (301), Expect = 6e-27
Identities = 109/358 (30%), Positives = 187/358 (52%), Gaps = 33/358 (9%)
Query: 430 QEAKTDQADGPREPPQSARRKRSY--KQAVSE-LDEEQHL---EDEELQPPRSKTPSSPC 483
QE + DQ + + RR+ + K A+ E L +EQ L E+EELQ +
Sbjct: 866 QEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRR-- 923
Query: 484 PASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRR 543
+ R R Q + L+ R +R R K+K+ Q+ E
Sbjct: 924 --QEQERQYREEEQLQQEEEQLLREEREKR-------RRQERERQYRKDKKLQQKEEQLL 974
Query: 544 KEEAEQLRRQ----KVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKF 599
EE E+ RRQ K E++ + EE +L REER ++ Q ER + K+E +++ EQ
Sbjct: 975 GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL 1034
Query: 600 AQIDEKTEKAKEERLAEEKAKKKAAAKKM--EEVEARRKQEEEA--RRLRWLQQEEEERR 655
+ EK + ER E+ + + +++ EE E RR+QE E R+ LQQEEE+
Sbjct: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL 1094
Query: 656 HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQL 715
+E +++++E + + R+ E ++ EQ +E RE+ RR++ R+ E+ ++E+E+ L
Sbjct: 1095 REEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLL 1154
Query: 716 AEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE 773
E+ +R ++ L ER+ +E E+ L+ ++EQL RE E++K+++E+ ERQ +EE+E
Sbjct: 1155 REEPEKRRRQEL--ERQYREEEE-LQQEEEQLLRE-EQEKRRQER----ERQYREEEE 1204
Score = 119 bits (299), Expect = 1e-26
Identities = 104/387 (26%), Positives = 194/387 (50%), Gaps = 58/387 (14%)
Query: 442 EPPQSARRKRSYKQAVSELDEEQHL-----------EDEELQPPRSKTPSSPCPASKVVR 490
E Q R++R ++ + L+EE+ L E++ LQ + + S + R
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWR 875
Query: 491 PLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQL 550
+R+ + P ++ + K L+ + +E +R+ E RR+E+ Q
Sbjct: 876 WQLEEERKRRRHTLYAKP-----ALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQY 930
Query: 551 RRQKV---EEDKRRRLEEVKLKREERLR-----KVLQARER--VEQMKEEKKKQIEQKFA 600
R ++ EE++ R E K +R+ER R K LQ +E + + E++++Q +K
Sbjct: 931 REEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKY 990
Query: 601 QIDEKTEKAKEERLAEEKAKKKAAA-----KKMEEVEARRKQE-EEARRLRWLQQEEEER 654
+ +E+ ++ +E+ L EE+ K++ +K +E++ +Q E R R LQ+ E +
Sbjct: 991 REEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQY 1050
Query: 655 RHQELLQKKKEE---EQERLRKAAEAKRLAEQREQERREQE---------RREQERREQE 702
R +E LQ+++E+ E+ R+ E +R + E+ ++E+E RR QER Q
Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC 1110
Query: 703 RREQERREQERQLAEQERR-----------REQERLQAERELQEREKALRLQKEQLQREL 751
R E+E +++E QL +ER RE+E +Q E E RE+ + ++++L+R+
Sbjct: 1111 REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY 1170
Query: 752 EEKKKKEEQQRLAERQLQEEQEKKAKE 778
E +EE Q+ E+ L+EEQEK+ +E
Sbjct: 1171 RE---EEELQQEEEQLLREEQEKRRQE 1194
Score = 119 bits (298), Expect = 1e-26
Identities = 75/270 (27%), Positives = 161/270 (59%), Gaps = 21/270 (7%)
Query: 527 RMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVE- 585
R +P++++ + RR+++ ++ R+ E +++ +E +R+ + R R+R E
Sbjct: 121 RFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEW 180
Query: 586 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ-------- 637
Q +EE++ + EQ + +TE+ +E + + K EE + +R++
Sbjct: 181 QEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQE 240
Query: 638 --EEEARRLRWLQQEEEERRHQELLQKKKE--EEQERLRKAAEAKRLAEQREQERREQER 693
E+E R+ + ++EEE+ +E Q+++E EE+E+LRK E + L +R++E ++Q+R
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL-ERQELRRERQEEEQQQQR 299
Query: 694 REQERREQERREQERREQERQLAEQERRREQERLQAEREL-----QEREKALRLQKEQLQ 748
+E++ + ++E+ERREQ+ + EQ+ RREQ+ + E++L + RE+ LR ++E+ +
Sbjct: 300 LRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER 359
Query: 749 RELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
RE + ++++EE++R E+QL+ EQ+ + ++
Sbjct: 360 REQQLRREQEEERR--EQQLRREQQLRREQ 387
Score = 119 bits (297), Expect = 2e-26
Identities = 98/365 (26%), Positives = 191/365 (52%), Gaps = 39/365 (10%)
Query: 436 QADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTF 495
+AD + S RK+ ++ E +E++ + ELQ + + R
Sbjct: 711 EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQ 770
Query: 496 LHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKV 555
++++ SA + + +R LR + +++ QR L +EE EQ RRQ+
Sbjct: 771 WQAEEKSERGRQRLSARPPLRE---QRERQLRAEERQQREQRF--LPEEEEKEQRRRQRR 825
Query: 556 EEDKRRRL--EEVKLKREERLRKVLQARERVE-------------------QMKEEKKKQ 594
E +K + EE +L+R ER +++ + + ++ Q++EE+K++
Sbjct: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885
Query: 595 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEA--RRLRWLQQEEE 652
+A+ + + KE++L +E+ ++ + EE E RR+QE+E R LQQEEE
Sbjct: 886 RHTLYAKPALQEQLRKEQQLLQEEEEE----LQREEREKRRRQEQERQYREEEQLQQEEE 941
Query: 653 ERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ-ERREQERREQERREQERREQ 711
+ +E ++K QER R+ + K+L ++ EQ E+ E+R ++ RE++ RE+E +Q
Sbjct: 942 QLLREE---REKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998
Query: 712 ERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQR--LAERQLQ 769
E + +E R ++ R + ER+ +++++ L+ ++EQL RE EK++ +E++R E +LQ
Sbjct: 999 EEEQLLREEREKRRRQEWERQYRKKDE-LQQEEEQLLREEREKRRLQERERQYREEEELQ 1057
Query: 770 EEQEK 774
+E+E+
Sbjct: 1058 QEEEQ 1062
Score = 116 bits (290), Expect = 1e-25
Identities = 101/365 (27%), Positives = 191/365 (52%), Gaps = 36/365 (9%)
Query: 429 QQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKV 488
+QE + +Q RE P+ RR++ K E +Q L E+ Q R + ++
Sbjct: 611 EQEERREQRL-KREEPEEERRQQLLKSEEQEERRQQQLRREQ-QERREQRLKREEEEERL 668
Query: 489 VRPLRTFLHTVQRNQMLMTPTSAP-RSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEA 547
+ L+ +R Q L R +KS I + +++ + RQ R +++
Sbjct: 669 EQRLKREHEEERREQELAEEEQEQARERIKSRIPK-WQWQLESEADARQSKVYSRPRKQE 727
Query: 548 EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTE 607
Q RRQ+ EE +RRR E++ + EER + +Q +EE+++ ++ Q +EK+E
Sbjct: 728 GQRRRQEQEEKRRRRESELQWQEEERAHR--------QQQEEEQRRDFTWQW-QAEEKSE 778
Query: 608 KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE-- 665
+ ++ A +++ + ++ A +Q+ E R L ++EE+E+R ++ +++KE
Sbjct: 779 RGRQRLSARPPLREQ----RERQLRAEERQQREQRFLP--EEEEKEQRRRQRREREKELQ 832
Query: 666 --EEQERLRKAAEAKRLAEQRE--QERREQERREQERREQERREQERREQERQ------- 714
EE+E+L++ A++L E+ + QE +E+ R +++RR+Q+ R Q E++R+
Sbjct: 833 FLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK 892
Query: 715 --LAEQERRREQERLQAERELQ--EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQE 770
L EQ R+ +Q + E ELQ EREK R ++E+ RE E+ +++EEQ ER+ +
Sbjct: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR 952
Query: 771 EQEKK 775
QE++
Sbjct: 953 RQERE 957
Score = 115 bits (289), Expect = 1e-25
Identities = 112/431 (25%), Positives = 213/431 (49%), Gaps = 40/431 (9%)
Query: 374 EQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPN------PKPAASSPETPSA 427
+++E +E E + EPE + E+ K E
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR 1141
Query: 428 GQQEAKTDQADGPREPPQSARRK---RSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCP 484
++E + ++ RE P+ RR+ R Y++ EE+ L EE + R +
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE 1201
Query: 485 ASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRK 544
++ R R + + + + P ++ ++ N ++ K +E ++ L
Sbjct: 1202 EEELQRQKRKQRYRDEDQRSDLKWQWEPEK--ENAVRDN---KVYCKGRENEQFRQL--- 1253
Query: 545 EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER----VEQMKEEKKKQIEQKFA 600
E QLR ++ ++D + L E + + E+ R+ Q R+R EQ++ E++K+ +++
Sbjct: 1254 -EDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDR 1312
Query: 601 QIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEA---RRLRWLQQEEEERRHQ 657
+ E+ + +EER EEK +++ +K E E ++ EE R+ R + EEE RHQ
Sbjct: 1313 KSQEEKQLLREER--EEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQ 1370
Query: 658 ELLQKKKEEEQERLRKAAEAKRLAEQRE---QERREQERREQERREQERREQ-ERREQER 713
E +K EEEQ R+ E K L E+++ QER +Q R++++R+ +E +Q R+E++R
Sbjct: 1371 EQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR 1430
Query: 714 QLAEQE---RRREQER--LQAEREL-QEREKALRLQKEQLQRELEEKKKKEEQQRLAERQ 767
+ E+E RR+E+ER L+ E++L QER + R +++ LQ E++ ++E+ R +
Sbjct: 1431 KFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR---KF 1487
Query: 768 LQEEQEKKAKE 778
L+EEQ+ + +E
Sbjct: 1488 LEEEQQLRRQE 1498
Score = 114 bits (284), Expect = 5e-25
Identities = 180/771 (23%), Positives = 318/771 (41%), Gaps = 94/771 (12%)
Query: 35 EEIQEE--AERMFTREFSKEPELMPKTPSQKN---RRKKRRISYVQDENRDPI-RRRLSR 88
E +Q+ +E+ RE + E + K +K R+++R+ Q+E RD + +R R
Sbjct: 526 ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
Query: 89 RKSRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATMALAAPSSPTPES 148
R+ R + RL + E++ + E RR R P E
Sbjct: 586 RQQRLKREQEERLEQRLKREEVERLEQEE----RREQRLKR------------EEPEEER 629
Query: 149 PTMLTKKPEDNHTQCQLVPVVEIGISERQNAEQHVTQLMSTEPLPRTLSPTPASATAPTS 208
L K E + Q ++ +++ EQ + + E L + L
Sbjct: 630 RQQLLKSEEQEERRQQ-----QLRREQQERREQRLKREEEEERLEQRLKREHEEERR--E 682
Query: 209 QGIPTSDEESTPKKSKARI------LES---ITVSSLMATPQDPKGQGVGTGRSASKLRI 259
Q + ++E ++ K+RI LES S + + P+ +GQ + + R
Sbjct: 683 QELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742
Query: 260 AQVSPGPRDSPAFPDSPWRERVLAPILPDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLA 319
+ A E+ +F+ + S+ R S P +
Sbjct: 743 ESELQWQEEERAHRQQQEEEQ------RRDFTWQWQAEEKSERGRQR----LSARPPLRE 792
Query: 320 QKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVE-VPQKVGSEQKEP 378
Q+ + +E +R R L ++ +E R L+ L E + ++ ++Q +
Sbjct: 793 QRERQLRAEERQ-QREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE 851
Query: 379 PEEAEPVAAAEPEVPENNGNNSWP---HNDTEIANSTPNPKPAASSPETPSAGQQEAKTD 435
E+ E + W + + T KPA E QQ + +
Sbjct: 852 EEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQ--EQLRKEQQLLQEE 909
Query: 436 QADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTF 495
+ + RE + RR+ +Q EE+ L+ EE Q R + + R R
Sbjct: 910 EEELQREEREKRRRQEQERQ----YREEEQLQQEEEQLLREEREKRRRQERE--RQYRKD 963
Query: 496 LHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKV 555
Q+ + L+ R +R + +E+E Q+ E +EE E+ RRQ+
Sbjct: 964 KKLQQKEEQLLGEEPEKR-------RRQEREKKYREEEELQQEEEQLLREEREKRRRQEW 1016
Query: 556 EEDKRRR----LEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 611
E R++ EE +L REER ++ LQ RER + +EE +++ EQ + E + +
Sbjct: 1017 ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL 1076
Query: 612 ERL--AEEKAKKKAAAKKMEEVEARRKQEEE--ARRLRWLQQEEEERRHQELLQKKKEEE 667
ER EE+ +++ EE E RR+QE E R LQQEEE+ +E +++++E
Sbjct: 1077 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQEL 1136
Query: 668 QERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERL 727
+ + R+ E ++ EQ +E E+ RR QE Q R E+E +++E QL R EQE+
Sbjct: 1137 ERQYREEEEVQQEEEQLLREEPEKRRR-QELERQYREEEELQQEEEQLL----REEQEKR 1191
Query: 728 QAERELQEREKALRLQKEQLQRELEEKKKKE---EQQRLAERQLQEEQEKK 775
+ ERE Q RE + EL+ +K+K+ ++ + ++ + Q E EK+
Sbjct: 1192 RQERERQYRE----------EEELQRQKRKQRYRDEDQRSDLKWQWEPEKE 1232
Score = 113 bits (283), Expect = 7e-25
Identities = 79/259 (30%), Positives = 153/259 (59%), Gaps = 15/259 (5%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
+E++++ R+ +E +QL R++ EE +RR+ + K + EE+L LQ RE ++E
Sbjct: 1301 REEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQL---LQEREEQPLRRQE 1357
Query: 591 KKKQIEQKFAQIDEKTEK--AKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
+ ++ ++ + E+ K +E+RL ++ ++K ++ + R+Q+ R R +
Sbjct: 1358 RDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFR 1417
Query: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQRE-QERREQERREQERREQERREQE 707
+EE++ QE +K +EEEQ+ R+ E K L E+++ ++ R ++ RE+E+ QER EQ+
Sbjct: 1418 EEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQ 1477
Query: 708 --RREQERQLAEQE---RRREQERLQAEREL--QEREKALRLQKEQLQRELEEKK--KKE 758
R+E++R+ E+E RR+E++R E+EL QE E+ +++QL R+ ++K ++E
Sbjct: 1478 LHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEE 1537
Query: 759 EQQRLAERQLQEEQEKKAK 777
+Q R ER Q Q++ K
Sbjct: 1538 QQLRRQERGQQRRQDRDRK 1556
Score = 113 bits (283), Expect = 7e-25
Identities = 101/396 (25%), Positives = 199/396 (50%), Gaps = 80/396 (20%)
Query: 448 RRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMT 507
R+ R +Q +S + ++ +EE Q R + R FL + Q L
Sbjct: 1414 RKFREEEQQLSRQERDRKFREEEQQVRRQERE-------------RKFL---EEEQQLRQ 1457
Query: 508 PTSAPRSVMKSFIKRNTPLRMDPKEKERQRLEN---LRRKEEAEQLRRQKV--EEDKRRR 562
+ ++ ++ +E++R+ LE LRR+E + R Q++ +E +R+
Sbjct: 1458 ERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKF 1517
Query: 563 LEEVK-LKREERLRKVLQARERVEQMK--EEKKKQIEQKFAQIDEKTEKAKEE------- 612
LEE + L R++R RK LQ +++ + + +++++ ++KF + ++ ++ +E+
Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577
Query: 613 ----RLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRW------------LQQEEEERRH 656
RL E+K +++ +K E E + +++E ++LR LQ+ EE++ H
Sbjct: 1578 DRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLH 1637
Query: 657 QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQER----REQE 712
++ +K EE+ +LR+ ++L R+++ RE+E+ QE EQ+ R QER RE+E
Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEE 1697
Query: 713 RQLAEQERRR-------------------EQERLQAERELQEREKALR----LQKEQLQR 749
+QL QER R E+E+L+ E E ++ + R L++EQL+
Sbjct: 1698 QQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRP 1757
Query: 750 ELEEK--KKKEEQQRLAE----RQLQEEQEKKAKEA 779
E EE+ +++E ++ E RQ +EEQ+ +++E+
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQES 1793
Score = 113 bits (282), Expect = 9e-25
Identities = 87/269 (32%), Positives = 158/269 (58%), Gaps = 24/269 (8%)
Query: 531 KEKERQRLENLRRK-EEAEQLRRQKVEEDKRR---RLEEVKLKREERLRKVLQARERVEQ 586
+E+ER+R + R E EQL R++ +E KRR EE +L REER K + R+ ++
Sbjct: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEK--RRRQETDR 1336
Query: 587 MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRW 646
E+++ ++++ Q + E+ ++ R EE ++ K +EE + R+QE E + L+
Sbjct: 1337 KFREEEQLLQEREEQPLRRQERDRKFR-EEELRHQEQGRKFLEEEQRLRRQERERKFLKE 1395
Query: 647 LQQEEEERRHQELLQ----KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE 702
QQ + R Q+L Q K +EEEQ+ R+ + K E+++ R+E+ER+ E +Q
Sbjct: 1396 EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQL 1455
Query: 703 RREQER--REQERQLAEQER----RREQER--LQAERELQEREKALRLQKEQLQRELEEK 754
R+E+ R RE+E+ L E+E R+E++R L+ E++L+ +E+ + ++++L+ + E+
Sbjct: 1456 RQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPER 1515
Query: 755 KKKEEQQRLAERQ-----LQEEQEKKAKE 778
K EE+Q+L +Q LQEEQ+ + +E
Sbjct: 1516 KFLEEEQQLHRQQRQRKFLQEEQQLRRQE 1544
Score = 112 bits (279), Expect = 2e-24
Identities = 121/501 (24%), Positives = 230/501 (45%), Gaps = 48/501 (9%)
Query: 304 RHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLL 363
RH+ A + Q L ++ L+ ++E ++R R ++ +E E+LL
Sbjct: 886 RHTLYAKPALQEQ-LRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944
Query: 364 NVEVPQKVGSEQ-------KEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPN-- 414
E ++ E+ K+ ++ E + EPE + E+
Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
Query: 415 ----PKPAASSPETPSAGQQEAKTDQADGPREPPQSAR---RKRSYKQAVSELDEEQHLE 467
K E + E + ++ RE + R R+R Y++ EE+ L
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064
Query: 468 DEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLR 527
EE + R + ++ R R Q + L+ R +R R
Sbjct: 1065 GEERETRRRQ---------ELERQYRKEEELQQEEEQLLREEPEKR-------RRQERER 1108
Query: 528 MDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVE-- 585
+E+E Q+ E +EE E+ RRQ++E R EEV+ + E+ LR+ + R R E
Sbjct: 1109 QCREEEELQQEEEQLLREEREKRRRQELERQYREE-EEVQQEEEQLLREEPEKRRRQELE 1167
Query: 586 -QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 644
Q +EE++ Q E++ + E+ EK ++ER + + +++ +K ++ R + E++ L
Sbjct: 1168 RQYREEEELQQEEE-QLLREEQEKRRQERERQYREEEELQRQKRKQ---RYRDEDQRSDL 1223
Query: 645 RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER-REQER 703
+W + E+E ++ K E E+ R+ +++ Q +Q+ + +QER REQER
Sbjct: 1224 KWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQER 1283
Query: 704 REQERREQERQLAEQ-ERRREQERLQAERELQEREKALRLQKEQLQRELE-EKKKKEEQQ 761
R ++R++ EQ ER ++E + +R+ QE ++ LR ++E+ +R E ++K +EE+Q
Sbjct: 1284 RRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQ 1343
Query: 762 RLAERQLQ----EEQEKKAKE 778
L ER+ Q +E+++K +E
Sbjct: 1344 LLQEREEQPLRRQERDRKFRE 1364
Score = 107 bits (267), Expect = 5e-23
Identities = 73/229 (31%), Positives = 139/229 (60%), Gaps = 20/229 (8%)
Query: 563 LEEVKLKREERLRKVLQARERVEQMK--EEKKKQIEQKFAQIDEKTEKAKEERLAE--EK 618
L+E K R + +LQ R + E + E + +Q+E++ Q + + +E LAE E+
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
Query: 619 AKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKK--------EEEQER 670
++K+ +++E+ + +R+ EE R+ + Q+ EE R +E LQ K +EEQ R
Sbjct: 155 SEKQ---ERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLR 211
Query: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730
R+ E +R + +E+++Q R Q+R QE E+E R++E L ++E + ++E Q +
Sbjct: 212 RRELLELRR---KGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ 268
Query: 731 RELQEREKALR-LQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
RELQE E+ LR L++++L+RE +E+++++++ R E+QL+ +QE++ +E
Sbjct: 269 RELQEEEEQLRKLERQELRRERQEEEQQQQRLR-REQQLRRKQEEERRE 316
Score = 107 bits (267), Expect = 5e-23
Identities = 73/251 (29%), Positives = 152/251 (60%), Gaps = 19/251 (7%)
Query: 531 KEKERQRLENLRRK--EEAEQLRRQKVEEDKRRRLE-EVKLKREERLRKVLQARERVEQM 587
+E++++R E R+ EE Q RRQK +E +R E E + +++ERL +R Q
Sbjct: 115 QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLE------QRDRQR 168
Query: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWL 647
++E+ + Q++ + +E+ +A+EE+L + K + +E + RR++ E RR
Sbjct: 169 RDEELWRQRQEWQEREER--RAEEEQL--QSCKGHETEEFPDEEQLRRRELLELRRKGRE 224
Query: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 707
+++++ R Q+ + + EEE++ RK R E++ QE Q +RE + E++ R+ E
Sbjct: 225 EKQQQRRERQDRVFQ--EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282
Query: 708 RREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQ 767
R+E R+ QE ++Q+RL+ E++L+ +++ R ++++ +RE +E+++++E++R E+Q
Sbjct: 283 RQELRRE--RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR--EQQ 338
Query: 768 LQEEQEKKAKE 778
L+ EQE++ ++
Sbjct: 339 LRREQEERREQ 349
Score = 62.8 bits (151), Expect = 1e-09
Identities = 62/268 (23%), Positives = 127/268 (47%), Gaps = 14/268 (5%)
Query: 429 QQEAKTDQADGP-REPPQSARRKRSYKQAVSELDEEQHLEDEELQPP-RSKTPSSPCPAS 486
+Q+ + + D RE Q RR+ ++ L EEQ L +EL+ R +
Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKF---LQEEQQLRRQELERKFREEEQLRQETEQ 1737
Query: 487 KVVRPLRTFLHTVQRNQML--MTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRK 544
+ +R + ++ Q+ R + LR + +E++ + E+ R+
Sbjct: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKF 1797
Query: 545 EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ--IEQKFAQI 602
E EQLR+++ E+ R + + K + EE + LQ E+ +++++E+ +Q E++FA
Sbjct: 1798 REEEQLRQEREEQQLRPQQRDGKYRWEE---EQLQLEEQEQRLRQERDRQYRAEEQFATQ 1854
Query: 603 DEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ-QEEEERRHQELLQ 661
++ + +E EE+ +++ +K+ E RR+Q+EE R + + + +E + H LL+
Sbjct: 1855 EKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLE 1914
Query: 662 KKKEE-EQERLRKAAEAKRLAEQREQER 688
+ +R + + + EQR Q R
Sbjct: 1915 PGTHQFASVPVRSSPLYEYIQEQRSQYR 1942
Score = 50.4 bits (119), Expect = 7e-06
Identities = 39/109 (35%), Positives = 64/109 (58%), Gaps = 9/109 (8%)
Query: 676 EAKRLAEQREQERREQERREQERREQERREQERRE-QERQLAEQE-RRREQERLQAEREL 733
+A L E++ +E Q+RR++E +Q R E ++RQL E+ +RR Q+R + EREL
Sbjct: 91 QATGLDEEKRARCDGKESLLQDRRQEE--DQRRFEPRDRQLEEEPGQRRRQKRQEQEREL 148
Query: 734 ----QEREKALRLQKEQLQRELEEK-KKKEEQQRLAERQLQEEQEKKAK 777
++ EK RL++ QR EE ++++E Q ER+ +EEQ + K
Sbjct: 149 AEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCK 197
Score = 31.6 bits (70), Expect = 3.5
Identities = 23/88 (26%), Positives = 45/88 (51%), Gaps = 11/88 (12%)
Query: 33 WLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDP------IRRRL 86
+L+E Q+ + R+F +E +L +T ++ RR++R +++E P +RR+
Sbjct: 1709 FLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQE 1768
Query: 87 SRRKSRS-----SQLSSRRLRSKDSVEK 109
RK R + ++LRS++S K
Sbjct: 1769 RDRKFREEEQLRQEREEQQLRSQESDRK 1796
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 132 bits (331), Expect = 2e-30
Identities = 96/290 (33%), Positives = 175/290 (60%), Gaps = 44/290 (15%)
Query: 529 DPKEKERQRLENLRRKEEA-----EQLRRQKV----EEDKRRRLEEVKLKREERLRKVLQ 579
+ +EK R++ E +RR+EE E++RRQ+ +E+K RRLEE+ ++EE++R++ +
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEE 384
Query: 580 ARERVEQMKE-EKKKQIEQKFAQIDEKTEKA-----KEERLAEEKAKKKAAAKKMEEVEA 633
E+++E E+K+Q E+K + +++ E+ +EE++ E++ K + KKM E
Sbjct: 385 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 444
Query: 634 RRKQEEEARRLRWLQQEEEERRHQELL--------QKKKEEEQERLRKAAEA-------- 677
+ ++E+ R Q++EE R +E + QK+K EQE++RK E
Sbjct: 445 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKM 504
Query: 678 ----KRLAEQREQERREQER-REQER--REQER--REQER--REQERQLAEQERR-REQE 725
+++ EQ E+ R++E+ REQE REQE REQE +EQE ++ EQE + +EQE
Sbjct: 505 HDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE 564
Query: 726 RLQAERE-LQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 774
+++ + E ++E+E+ +R QKE+++ + E+ ++EE+ R E +QE++EK
Sbjct: 565 KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK 614
Score = 125 bits (314), Expect = 2e-28
Identities = 83/268 (30%), Positives = 165/268 (61%), Gaps = 28/268 (10%)
Query: 529 DPKEKERQRLENLRRKEEAEQLRRQKV----EEDKRRRLEEVKLKREERLRKVLQARERV 584
+ +EK R++ E +R +EE ++RRQ+ +E+K RR EE+ ++EE++R++ E +
Sbjct: 318 EQEEKIREQEEKIREQEE--KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRL----EEM 371
Query: 585 EQMKEEKKKQIEQKF---AQIDEKTEK-AKEERLAEEKAKKKAAAKKMEEVEARRKQEEE 640
KEEK +++E+K +I E+ EK +EE++ E++ +++ AK + E R+QEE+
Sbjct: 372 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 431
Query: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER-R 699
R +EE+ H++ +++E+ QE+ + +++ EQ E R++++ EQE+ R
Sbjct: 432 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIR 491
Query: 700 EQE----RREQERREQERQLAEQER---RREQERLQAERELQEREKALRLQKEQLQR--- 749
+QE R+E++ +QE ++ EQE R+E++ + E +++E+E+ +R Q+E +Q
Sbjct: 492 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEE 551
Query: 750 ---ELEEKKKKEEQQRLAERQLQEEQEK 774
E EEK +++E+ R E +++E++EK
Sbjct: 552 KMGEQEEKMQEQEKMRRQEEKIREQEEK 579
Score = 124 bits (311), Expect = 4e-28
Identities = 104/464 (22%), Positives = 231/464 (49%), Gaps = 40/464 (8%)
Query: 318 LAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKE 377
L +K LV ++S ++ + L +K LER + Q++ +E
Sbjct: 226 LQEKLQLVESEKSEIQLNVKELKRK----------------LERAKLLLPQQQLQAEADH 269
Query: 378 PPEEAEPVAAA-EPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQ 436
+E + V+A + +V EN W + + + E Q+E +Q
Sbjct: 270 LGKELQSVSAKLQAQVEENE---LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQ 326
Query: 437 ADGPREPPQSARRKRSYKQAVSELDEEQHLEDE---ELQPPRSKTPSSPCPASKVVRPLR 493
+ RE + RR+ ++ + E +E+ ++E E + + + +R L
Sbjct: 327 EEKIREQEEKMRRQ---EEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE 383
Query: 494 TFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRM-DPKEKERQRLENLRRKEEAEQLRR 552
+H ++ + + + ++ +M +EK R++ E +R +E+ +
Sbjct: 384 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 443
Query: 553 QKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEE 612
+K+ E ++ R EE + ++EE R+ + RE+ E ++++K ++K + +EK + +E+
Sbjct: 444 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEK 503
Query: 613 RLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLR 672
+E+ ++ K + E R+QEE+ R +QEE+ R +E++Q+++E+ E
Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKIR-----EQEEKIREQEEMMQEQEEKMGE--- 555
Query: 673 KAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERE 732
+ +++ EQ + R+E++ REQE + +E++E+ R ++E+ ++E+ REQE + E+E
Sbjct: 556 ---QEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE 612
Query: 733 --LQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 774
+ E+E+ + Q+E++Q + E+ +++EE+ E +L++++EK
Sbjct: 613 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 656
Score = 120 bits (300), Expect = 8e-27
Identities = 72/260 (27%), Positives = 159/260 (61%), Gaps = 13/260 (5%)
Query: 527 RMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR----KVLQARE 582
+M +EK R++ E + +E+ + +++ +E K R EE ++EE++R K+ + E
Sbjct: 385 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 444
Query: 583 RV---EQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
++ E+++EE+K+Q +++ + +EK + +E +EK ++ +K EE R++++
Sbjct: 445 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKM 504
Query: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 699
+ + +QEE+ R +E +++++E+ +E+ K E + + +++E++ EQE + QE+
Sbjct: 505 HDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE 564
Query: 700 EQERREQERREQERQLAEQ-ERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKE 758
+ R+E++ REQE ++ EQ E+ REQ E ++ E+E+ +R Q+E +Q + E+ ++E
Sbjct: 565 KMRRQEEKIREQEEKIREQKEKIREQ-----EEKIWEQEEKIREQEEMMQEQEEKMWEQE 619
Query: 759 EQQRLAERQLQEEQEKKAKE 778
E+ E ++QE++EK ++
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQ 639
Score = 115 bits (288), Expect = 2e-25
Identities = 86/299 (28%), Positives = 167/299 (55%), Gaps = 38/299 (12%)
Query: 513 RSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL---- 568
R + + RNT + KEK + E L+ E + + V+E KR+ LE KL
Sbjct: 202 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRK-LERAKLLLPQ 260
Query: 569 -----------KREERLRKVLQAR-------ERVEQMKEEKKKQIEQKFAQIDEKTEKAK 610
K + + LQA+ R+ Q +EEK + E+K + +EK ++ +
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE-Q 319
Query: 611 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARR----LRWLQQEEEERRHQELLQKKKEE 666
EE++ E++ K + +KM E ++EE R + W ++EE+ RR +E++ +K+E+
Sbjct: 320 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW-EKEEKMRRLEEMMWEKEEK 378
Query: 667 EQERLRKAAEAKRLAEQREQERREQERREQERREQE-----RREQERREQERQLAEQERR 721
+E K E +++ EQ E+ + E++ REQE+R+++ R+E++ REQE ++ EQE++
Sbjct: 379 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 438
Query: 722 --REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
R++E++ + +++E EK R ++E++ R+ E+ +++EE R E+ ++E+ +K +E
Sbjct: 439 MWRQEEKIHEQEKIREEEK--RQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEE 495
Score = 97.8 bits (242), Expect = 4e-20
Identities = 75/219 (34%), Positives = 135/219 (61%), Gaps = 26/219 (11%)
Query: 531 KEKERQRLENLRRKEEA----EQLRRQKV---EEDKRRRLEEVKLKREERLR-KVLQARE 582
+E++RQ E + R+EE E++ RQK E++K R+ EE ++EE++ + + RE
Sbjct: 454 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIRE 513
Query: 583 RVEQM--KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE 640
+ E+M +EEK ++ E+K + +EK + +EE + E++ K +KM+E E R+QEE+
Sbjct: 514 QEEKMWRQEEKIREQEEKIREQEEKIRE-QEEMMQEQEEKMGEQEEKMQEQEKMRRQEEK 572
Query: 641 ARRLRWLQQEEEERRHQELLQKKKE---EEQERLRKAAEAKRLAEQR--EQERR--EQER 693
R +QEE+ R +E +++++E E++E++R+ E + E++ EQE + EQE
Sbjct: 573 IR-----EQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627
Query: 694 REQERREQERREQERR-EQERQLAEQERR--REQERLQA 729
+ QE+ E+ RR++E+ EQE +L +QE + QE L+A
Sbjct: 628 KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 666
Score = 91.3 bits (225), Expect = 4e-18
Identities = 62/206 (30%), Positives = 118/206 (57%), Gaps = 29/206 (14%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKV--EEDKRRRLEEVKLKREERLRKVLQARERVEQMK 588
KEK ++ E +R++EE + +K+ +E+K R EE ++EE++ RE+ E+++
Sbjct: 481 KEKMHEQ-EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI------REQEEKIR 533
Query: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
E+++K EQ EE + E++ K +KM+E E R+QEE+ R +
Sbjct: 534 EQEEKIREQ-------------EEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIR-----E 575
Query: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERR--EQERREQERREQ 706
QEE+ R +E +++++E+ E+ K E + + +++E++ EQE + EQE + QE+ E+
Sbjct: 576 QEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 635
Query: 707 ERREQERQLAEQERRREQERLQAERE 732
RR++E+ ++ R R+QE E +
Sbjct: 636 MRRQEEKMWEQEVRLRQQEEKMQEHQ 661
Score = 84.3 bits (207), Expect = 5e-16
Identities = 66/251 (26%), Positives = 134/251 (53%), Gaps = 32/251 (12%)
Query: 531 KEKERQRLENLRRKEEAEQLR--RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK 588
K+K + +E L ++ +A L R + +++ L+E K +E+L+ V + ++
Sbjct: 188 KKKADRYIEELTKERDALSLELYRNTITDEE---LKEKNAKLQEKLQLVESEKSEIQLNV 244
Query: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
+E K+++E+ + ++ +A+ + L +E A +++A+ ++ E RL Q
Sbjct: 245 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA------KLQAQVEENELWNRLNQ-Q 297
Query: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQER 708
QEE+ R +E +Q+ +E+ QE+ E++ REQE + +E+ E+ R
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQ-------------------EEKIREQEEKIREQEEKMR 338
Query: 709 REQERQLAEQERRREQERLQAERELQERE-KALRLQKEQLQRELEEKKKKEEQQRLAERQ 767
R++E ++E+ R QE + E+E + R + + +KE+ RELEEK ++E+ R E +
Sbjct: 339 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK 398
Query: 768 LQEEQEKKAKE 778
QEE++ + +E
Sbjct: 399 RQEEEKIREQE 409
Score = 73.6 bits (179), Expect = 8e-13
Identities = 70/294 (23%), Positives = 141/294 (47%), Gaps = 45/294 (15%)
Query: 529 DPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVL-QARERVEQM 587
D ++ Q E LRR+ EA Q+ ++ ++ L+ + ++++ +AR+ + ++
Sbjct: 109 DEQKASHQHQEALRRELEA-QVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAA------AKKMEEVEARRKQEEEA 641
+ K E + A T+K K +R EE K++ A + + E + K +
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 642 RRLRWLQQEEE-------------ERRHQELLQKKKEEEQERLRKAAEA----------- 677
+L+ ++ E+ ER L Q++ + E + L K ++
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 287
Query: 678 ----KRLAEQREQERREQERREQERREQERREQER-REQERQLAEQER--RREQERLQAE 730
RL +Q+E++ QE + QE E+ + ++E+ REQE ++ EQE RR++E + +
Sbjct: 288 NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEK 347
Query: 731 RELQEREKALRLQKEQLQRELE------EKKKKEEQQRLAERQLQEEQEKKAKE 778
E R++ + +KE+ R LE E+K +E ++++ E++ EQE+K +E
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 401
Score = 70.5 bits (171), Expect = 7e-12
Identities = 66/249 (26%), Positives = 120/249 (48%), Gaps = 25/249 (10%)
Query: 429 QQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKV 488
+QE K + + RE + ++ ++Q EE+ E EE+ + K
Sbjct: 441 RQEEKIHEQEKIREEEKRQEQEEMWRQ------EEKIREQEEIWRQKEKMHEQ------- 487
Query: 489 VRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAE 548
+R V R + M + + R + +EK R++ E +R +EE
Sbjct: 488 -EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMM 546
Query: 549 QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEK 608
Q + +K+ E + + E+ K++R+E + RE+ E+++E+K+K EQ+ +I E+ EK
Sbjct: 547 QEQEEKMGEQEEKMQEQEKMRRQEE-----KIREQEEKIREQKEKIREQE-EKIWEQEEK 600
Query: 609 AK--EERLAEEKAKKKAAAKKM-EEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 665
+ EE + E++ K +KM E+ E ++QEE+ RR E+E R Q+ ++K +
Sbjct: 601 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ--EEKMQ 658
Query: 666 EEQERLRKA 674
E QE L A
Sbjct: 659 EHQEHLEAA 667
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 131 bits (330), Expect = 3e-30
Identities = 87/266 (32%), Positives = 170/266 (63%), Gaps = 25/266 (9%)
Query: 529 DPKEKERQRLENLRRKEEA-----EQLRRQKV----EEDKRRRLEEVKLKREERLRKVLQ 579
+ +EK R++ E +RR+EE E++RRQ+ +E+K R LEE K+ +E++R+ +
Sbjct: 306 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE-KMHEQEKIREQEE 364
Query: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
R+ E+++E++K+Q ++ E+ + +EE++ E++ + +KM E E + ++E
Sbjct: 365 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQE 424
Query: 640 EARRLRWLQQEEEERRHQELL---QKKKEEEQERLRKAAEAKRLAEQR--EQERR--EQE 692
E + +QEE+ RR +E + +KK E++E++R+ E + E++ EQE + EQE
Sbjct: 425 EEMQ----EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQE 480
Query: 693 RREQERREQERREQER-REQERQLAEQERR-REQERLQAERE--LQEREKALRLQKEQLQ 748
+ QE+ E+ RR++E+ REQE+++ EQE + REQE + E+E + E+E+ + Q+E++Q
Sbjct: 481 AKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 540
Query: 749 RELEEKKKKEEQQRLAERQLQEEQEK 774
+ E+ +++EE+ R E +L++++EK
Sbjct: 541 EQEEKMRRQEEKMREQEVRLRQQEEK 566
Score = 129 bits (324), Expect = 1e-29
Identities = 82/255 (32%), Positives = 162/255 (63%), Gaps = 18/255 (7%)
Query: 526 LRMDPKEKERQRLENLRRKEEAEQLRRQKV--EEDKRRRLEEVKLKREERLRKVLQARER 583
L +EK ++ E ++ +EE Q + +K+ +E+K RR EE+ ++EE++R+ +E
Sbjct: 282 LNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRR----QEE 337
Query: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 643
+ KEEK +++E+K + EK + +E+R EEK +++ +K +E EA+ ++EE R
Sbjct: 338 MMWEKEEKIRELEEKMHE-QEKIREQEEKRQEEEKIREQ---EKRQEQEAKMWRQEEKIR 393
Query: 644 LRWLQQEEEERRHQELLQKKKEEEQERLRKAAE-AKRLAEQREQERREQER-REQERREQ 701
+QEE+ R +E++Q+++E+ E+ K E + + EQ E+ RR++E+ REQE++ +
Sbjct: 394 ----EQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 702 ERREQERREQERQLAEQERRREQERLQAERE--LQEREKALRLQKEQLQRELEEKKKKEE 759
E+ E+ R ++E ++E+ EQE E+E +QE+E+ +R Q+E+++ + ++ +++EE
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEE 509
Query: 760 QQRLAERQLQEEQEK 774
+ R E +QE++EK
Sbjct: 510 KIREQEEMMQEQEEK 524
Score = 118 bits (295), Expect = 3e-26
Identities = 74/257 (28%), Positives = 161/257 (62%), Gaps = 11/257 (4%)
Query: 520 IKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQ 579
++R + + +EK R++ E + KEE + +K+ E ++ R +E K + EE++R+ +
Sbjct: 318 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 377
Query: 580 ARERVEQM--KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEAR-RK 636
+E+ +M +EEK ++ E+K + +E ++ +EE++ E++ K ++M+E E + R+
Sbjct: 378 RQEQEAKMWRQEEKIREQEEKIREQEEMMQE-QEEKMGEQEEKMWEQEEEMQEQEEKMRR 436
Query: 637 QEEEARRL--RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERR 694
QEE+ R + +QEE+ R +E++Q+++E+ E+ K E E + QE+ E+ RR
Sbjct: 437 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQ----EAKMQEQEEKMRR 492
Query: 695 EQER-REQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEE 753
++E+ REQE++ +E+ E+ R+ E + +E++ + E ++ E+E+ ++ Q+E+++R+ E+
Sbjct: 493 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 552
Query: 754 KKKKEEQQRLAERQLQE 770
+++E + R E ++QE
Sbjct: 553 MREQEVRLRQQEEKMQE 569
Score = 117 bits (293), Expect = 5e-26
Identities = 84/293 (28%), Positives = 165/293 (56%), Gaps = 32/293 (10%)
Query: 513 RSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE 572
R + + RNT + KEK + E L+ E + + V+E KR KL+R +
Sbjct: 190 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKR------KLERAK 243
Query: 573 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDE-----KTEKAKEERLAEEKAKKKAAAKK 627
L Q + + + +E + + AQ++E + + +EE++ ++ K + +K
Sbjct: 244 LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEK 303
Query: 628 MEEVEAR-RKQEEEARRLRWLQQEEEE--RRHQELLQKKKEEEQERLRKAAEAKRLAEQR 684
++E E + R+QEE+ RR + E+EE RR +E++ +K+E+ +E K E +++ EQ
Sbjct: 304 IQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 363
Query: 685 EQERREQERREQERREQE-----RREQERREQERQLAEQER----------RREQERLQA 729
E+ + E++ REQE+R+++ R+E++ REQE ++ EQE +E++ +
Sbjct: 364 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQ 423
Query: 730 ERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAER-QLQEEQEKKAKEAAG 781
E E+QE+E+ +R Q+E+++ + EKK +E+++++ E+ ++ +EQE+K E G
Sbjct: 424 EEEMQEQEEKMRRQEEKIREQ--EKKIREQEEKIREQEEMMQEQEEKMGEQEG 474
Score = 95.9 bits (237), Expect = 2e-19
Identities = 60/251 (23%), Positives = 138/251 (54%), Gaps = 7/251 (2%)
Query: 531 KEKERQRLENLRRKEEAEQLR--RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK 588
K+K + +E L ++ +A L R + +++ L+E K +E+L+ V + ++
Sbjct: 176 KKKADRYIEELTKERDALSLELYRNTITDEE---LKEKNAKLQEKLQLVESEKSEIQLNV 232
Query: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAK-KMEEVEARRKQEEEARRLRWL 647
+E K+++E+ + ++ +A+ + L +E A + ++EE E + ++ W
Sbjct: 233 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR 292
Query: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 707
Q+E+ + R +E +Q+++E+ +E+ K + + ++E++ R QE E+ E+ R +E
Sbjct: 293 QEEKIQER-EEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 351
Query: 708 RREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQ 767
+ ++ ++ EQE +R++E E+E ++ ++A ++E+ RE EEK +++E+ + +
Sbjct: 352 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEE 411
Query: 768 LQEEQEKKAKE 778
EQE+K E
Sbjct: 412 KMGEQEEKMWE 422
Score = 67.0 bits (162), Expect = 8e-11
Identities = 61/276 (22%), Positives = 133/276 (48%), Gaps = 30/276 (10%)
Query: 529 DPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVL-QARERVEQM 587
D ++ Q E LRR+ EA Q++ ++ ++ L+ + ++++ +AR+ + ++
Sbjct: 97 DEQKASHQHQEALRRELEA-QVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 155
Query: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAK------KMEEVEARRKQEEEA 641
+ K E + A T+K K +R EE K++ A + + E + K +
Sbjct: 156 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 215
Query: 642 RRLRWLQQEEEE-------------RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER 688
+L+ ++ E+ E R L Q++ + E + L K ++ Q + E
Sbjct: 216 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 275
Query: 689 REQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ 748
E R +++E++ QE + QER E++ + ++E+++ + E R++ + +KE+
Sbjct: 276 NELWNRLNQQQEEKMWRQEEKIQER---EEKIQEQEEKIREQEEKMRRQEEMMWEKEEKM 332
Query: 749 RELE------EKKKKEEQQRLAERQLQEEQEKKAKE 778
R E E+K +E ++++ E++ EQE+K +E
Sbjct: 333 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 368
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 129 bits (323), Expect = 2e-29
Identities = 87/280 (31%), Positives = 163/280 (58%), Gaps = 33/280 (11%)
Query: 529 DPKEKERQRLENLRRKEEA--EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQ 586
+ +EK R++ E + R+EE EQ ++ + +E K R EE +++ERLR+ + E+
Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 418
Query: 587 MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR- 645
M E+ +K E+K Q EK + +EE++ EE+ ++ K EE E R+QEE+ ++
Sbjct: 419 MWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 478
Query: 646 --WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQER--------RE 695
W Q+E+E ++ + QK+K EQE++++ E ++ EQ E+ R ++E R+
Sbjct: 479 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE--KIWEQEEKIRDQEEMWGQEKKMWRQ 536
Query: 696 QERREQE----RREQERREQERQLAEQERRRE-------------QERLQAERELQEREK 738
++ REQE +E++ R+QE+++ +QE R E +E+++ E ++EREK
Sbjct: 537 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREK 596
Query: 739 ALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
+R ++E++ RE EEK +++E++ + + EQE+K +E
Sbjct: 597 KMR-EEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQE 635
Score = 125 bits (314), Expect = 2e-28
Identities = 82/269 (30%), Positives = 163/269 (60%), Gaps = 22/269 (8%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKV--EEDKRRRLEEVKLKREERL-RKVLQARERVEQM 587
+EKE + + LR +EE Q + +K+ +E+K R EE ++EERL + Q RE+ ++M
Sbjct: 333 QEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 392
Query: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEA------ 641
++++++ EQ ++ EK E+ +E+ E+ +K KKM+E E + + +EE
Sbjct: 393 RDQEERMWEQD-ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEER 451
Query: 642 --RRLRWLQQEEEERRHQ-ELLQKKKEEEQERLRKAAEAKRLAEQRE-----QERREQER 693
R + +++EEE R Q E +QK++E E+ K + +RL EQ+E ++ +EQE
Sbjct: 452 IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 511
Query: 694 REQERREQERREQERREQERQLAEQERRREQE--RLQAERELQEREKALRLQKEQLQREL 751
+ E+ E+ R ++E QE+++ QE+ REQE + E +++++E+ + Q+E+++++
Sbjct: 512 KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKT 571
Query: 752 EEKKKK--EEQQRLAERQLQEEQEKKAKE 778
+E++KK ++++++ E + E+EKK +E
Sbjct: 572 QEQEKKTWDQEEKMREEERMREREKKMRE 600
Score = 122 bits (306), Expect = 2e-27
Identities = 112/440 (25%), Positives = 217/440 (49%), Gaps = 50/440 (11%)
Query: 369 QKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAG 428
QK EQ+E +E E + E W + + E
Sbjct: 340 QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER-----LWEQEKQMREQEQKMRD 394
Query: 429 QQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKV 488
Q+E +Q + RE + R + + V ++ EE+ ++++E +++ +
Sbjct: 395 QEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQE---KKTRDQEEKMQEEER 451
Query: 489 VRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPL-RMDPKEKERQRLENLRRK--- 544
+R +R + + R + K+ + + KE ++QRL + K
Sbjct: 452 IR---------EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 502
Query: 545 EEAEQLRRQKV-EEDKRRRLEEVKLKREERLRKVLQARERVEQM--KEEKKKQIEQKFAQ 601
+E Q + +K+ E++++ R +E +E+++ + + RE+ +QM +EEK + EQK
Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 562
Query: 602 IDEKTEKA----------KEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE 651
+E+ EK +EE++ EE+ ++ K EE E R+QEE+ + QE+
Sbjct: 563 QEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 622
Query: 652 EER--RHQELLQKKKE---EEQERL----RKAAEAKRLAEQREQERREQERREQER-REQ 701
EE+ +E +Q+++E E++E++ K E +RL EQ+E+ ++ +EQE+ +EQ
Sbjct: 623 EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQ 682
Query: 702 ERREQERREQERQLAEQERRR-EQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQ 760
E + E+ + E++ EQE++ +QE+++ E ++EREK +R ++E++ RE EEK +EQ
Sbjct: 683 EEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMR-EEEEMMREQEEKM--QEQ 739
Query: 761 QRLAERQLQE--EQEKKAKE 778
+ + Q +E EQE+K E
Sbjct: 740 EEKMQEQEEEMWEQEEKMWE 759
Score = 117 bits (292), Expect = 6e-26
Identities = 97/344 (28%), Positives = 192/344 (55%), Gaps = 41/344 (11%)
Query: 461 DEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFI 520
+EE ++ ELQ K P + S++ ++ ++R + L+ P ++ +
Sbjct: 220 NEELKKKNAELQ---EKLPLAESEKSEIQLNVKELKRKLERAKFLL-PQVQTNTLQEEMW 275
Query: 521 KRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEE--------DKRRRLEEVKLKREE 572
++ LR + ++K R++ E + R+EE + + K+ E +KR R +E +L+ +E
Sbjct: 276 RQEEELR-EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQE 334
Query: 573 R-LRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKA--KEERLAEEKAKKKAAAKKME 629
+ LR+ + RE+ EQM+E+++K EQ+ ++ E+ EK +EERL E++ + + +KM
Sbjct: 335 KELREQKELREQEEQMQEQEEKMWEQE-EKMREQEEKMWRQEERLWEQEKQMREQEQKMR 393
Query: 630 EVEARRKQEEEARRLRWLQQEEEERRHQE--------LLQKKKEEEQERLRKAAEAKRLA 681
+ E R +++E L+++EE R QE + ++KK +EQE+ + E K
Sbjct: 394 DQEERMWEQDER-----LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQE 448
Query: 682 EQREQERREQERREQE-RREQERREQERRE-----QERQLAEQERRREQERLQAERELQE 735
E+R +ER ++ R E+E REQE + Q++ E +E++ +Q ++E+L + ++QE
Sbjct: 449 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 508
Query: 736 REKALRLQKEQL--QREL---EEKKKKEEQQRLAERQLQEEQEK 774
+E+ + Q+E++ Q E+ E+K ++E+ R E Q+ E++EK
Sbjct: 509 QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 552
Score = 114 bits (285), Expect = 4e-25
Identities = 73/255 (28%), Positives = 152/255 (59%), Gaps = 21/255 (8%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
+E+ER R + +EE E +R Q E+K + EE ++EE++ E+ E+M+E+
Sbjct: 586 REEERMREREKKMREEEEMMREQ---EEKMQEQEEKMQEQEEKMW------EQEEKMQEQ 636
Query: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE---EARRLRWL 647
++K EQ+ +++ + +++RL E+K +K +KM+E E ++QEE E ++
Sbjct: 637 EEKMWEQEEKMWEQEEKMWEQQRLPEQK-EKLWEHEKMQEQEKMQEQEEKIWEQEKMEKK 695
Query: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 707
QE+E++ + +++E +ER +K E + + ++E++ +EQE + QE+ E+ ++E
Sbjct: 696 TQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE 755
Query: 708 RR-EQERQLAEQERRREQ-------ERLQAERELQEREKALRLQKEQLQRELEEKKKKEE 759
+ EQE ++ EQ+R EQ E++Q + ++ E+E+ +R Q+E+++ + E+ + +EE
Sbjct: 756 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEE 815
Query: 760 QQRLAERQLQEEQEK 774
+ R E ++ ++EK
Sbjct: 816 KMRGQEEKMWGQEEK 830
Score = 112 bits (279), Expect = 2e-24
Identities = 74/260 (28%), Positives = 159/260 (61%), Gaps = 21/260 (8%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
+++E+ R + + ++ E++ ++ E++K+ +E K++ EER+R+ RE+ + +EE
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRE----REKKMREEEE 603
Query: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 650
++ E+K + +EK ++ +EE++ E++ K + +KM E E + ++EE W QQ
Sbjct: 604 MMREQEEKMQEQEEKMQE-QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEK---MWEQQR 659
Query: 651 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERR----EQERREQERREQ 706
E++ ++L + +K +EQE++++ E E+ E++ +EQE++ E+ R E+ RE+
Sbjct: 660 LPEQK-EKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRER 718
Query: 707 ER--REQERQLAEQERR---REQERLQAERELQEREKALRLQKEQL---QRELEEKKKKE 758
E+ RE+E + EQE + +E++ + E E+ E+E+ + Q+E++ QR E+K+K
Sbjct: 719 EKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 778
Query: 759 EQQRLAERQLQEEQEKKAKE 778
E +++ E++ EQE+K ++
Sbjct: 779 EHEKMQEQEKIWEQEEKMRD 798
Score = 112 bits (279), Expect = 2e-24
Identities = 71/256 (27%), Positives = 148/256 (57%), Gaps = 10/256 (3%)
Query: 527 RMDPKEKERQRLENLRRKEEA--EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQAR-ER 583
+M +E+ R+R + +R +EE EQ + + +E+K + EE ++EE++++ + E+
Sbjct: 584 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643
Query: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 643
E+M E+++K EQ+ ++ E+ EK E +E+ K + +K+ E E K+ +E +
Sbjct: 644 EEKMWEQEEKMWEQQ--RLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK 701
Query: 644 LRWLQQEEEERRHQELLQKKKEEEQERLR----KAAEAKRLAEQREQERREQERREQERR 699
W Q++ E +KK EE+E +R K E + +++E+E EQE + E+
Sbjct: 702 KTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQE 761
Query: 700 EQERREQERREQERQLAEQERRREQERL-QAERELQEREKALRLQKEQLQRELEEKKKKE 758
E+ +Q EQ+ +L E E+ +EQE++ + E +++++E+ +R Q+E+++ + E+ + +E
Sbjct: 762 EKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821
Query: 759 EQQRLAERQLQEEQEK 774
E+ E ++ ++EK
Sbjct: 822 EKMWGQEEKMWGQEEK 837
Score = 104 bits (259), Expect = 4e-22
Identities = 76/272 (27%), Positives = 154/272 (56%), Gaps = 29/272 (10%)
Query: 513 RSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE 572
R + + RNT + K+K + E L E + + V+E KR KL+R +
Sbjct: 206 RDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKR------KLERAK 259
Query: 573 RLRKVLQARERVEQM--KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEE 630
L +Q E+M +EE+ ++ E+K + +EK + +EERL E++ K + +KM
Sbjct: 260 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR-QEERLREQEGKMREQEEKMWR 318
Query: 631 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAK-RLAEQREQERR 689
E R +++E+ L+++E+E R Q+ L++++E+ QE+ K E + ++ EQ E+ R
Sbjct: 319 QEKRLREQEKE-----LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWR 373
Query: 690 EQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK---EQ 746
++ER ++ ++ +EQ+ R+QE ++ EQ+ R L+E+E+ +R Q+ EQ
Sbjct: 374 QEERLWEQEKQMREQEQKMRDQEERMWEQDER-----------LREKEERMREQEKMWEQ 422
Query: 747 LQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
+++ EEKK +E++++ +++ + ++E++ +E
Sbjct: 423 VEKMREEKKMQEQEKKTRDQEEKMQEEERIRE 454
Score = 102 bits (254), Expect = 2e-21
Identities = 102/497 (20%), Positives = 227/497 (45%), Gaps = 57/497 (11%)
Query: 318 LAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKE 377
L +K + +QE + + + +K +E R ++ ++ +++ +K+
Sbjct: 406 LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTR-------DQEEKMQEEERIREREKK 458
Query: 378 PPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQA 437
EE E + E ++ + N W + E + + Q+E +Q
Sbjct: 459 MREEEETMREQEEKMQKQE-ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 517
Query: 438 DGPREPPQS-ARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFL 496
+ R+ + + K+ ++Q E+Q E EE R + ++ + +
Sbjct: 518 EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM--RDQEQKMWDQEERMEKKTQEQE 575
Query: 497 HTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEA--EQLRRQK 554
+ M R K + +R + +EK +++ E ++ +EE EQ + +
Sbjct: 576 KKTWDQEEKMREEERMREREKKMREEEEMMR-EQEEKMQEQEEKMQEQEEKMWEQEEKMQ 634
Query: 555 VEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKT-EKAKEER 613
+E+K EE ++EE++ + + E+ E++ E +K Q ++K + +EK E+ K E+
Sbjct: 635 EQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEK 694
Query: 614 LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ----- 668
+E+ KK +KM E E+ R++E++ R + +E+EE+ ++ + +++EE+
Sbjct: 695 KTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQE 754
Query: 669 ----ERLRKAAEAKRLAEQREQERREQERREQER---REQERREQE---RREQERQLAEQ 718
E+ K E +RL EQ+E+ ++ +EQE+ +E++ R+QE R ++E+ ++
Sbjct: 755 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQE 814
Query: 719 ERRREQERL---------------------------QAERELQEREKALRLQKEQLQREL 751
E+ R QE + E ++Q +E+ +R Q+E+++ +
Sbjct: 815 EKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQE 874
Query: 752 EEKKKKEEQQRLAERQL 768
E+ +++EE+ R E ++
Sbjct: 875 EKMREQEEKMRGQEEKI 891
Score = 96.3 bits (238), Expect = 1e-19
Identities = 82/371 (22%), Positives = 179/371 (48%), Gaps = 55/371 (14%)
Query: 429 QQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKV 488
+QE K + + K++ +Q D+E+ + +EE R K
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKK---------- 597
Query: 489 VRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAE 548
++ + +M + ++ + +EK +++ E + +EE
Sbjct: 598 ----------MREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKM 647
Query: 549 QLRRQKVEEDKRRRLEEVKLKREERLR---KVLQARERV-EQMKEEKKKQIEQKFAQIDE 604
+ +K+ E +R ++ KL E+++ K+ + E++ EQ K EKK Q ++K
Sbjct: 648 WEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK------ 701
Query: 605 KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKK 664
+ +E++ EE++ ++ K EE E R+QEE+ + +QEE+ + +E + +++
Sbjct: 702 --KTWDQEKMREEESMREREKKMREEEEMMREQEEKMQ-----EQEEKMQEQEEEMWEQE 754
Query: 665 EEEQERLRKAAEAKRLAEQRE-----QERREQER-REQERREQERREQERREQERQLAEQ 718
E+ E+ K E +RL EQ+E ++ +EQE+ EQE + +++ E+ R ++E+ ++
Sbjct: 755 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQE 814
Query: 719 ERRREQERLQ---------AERELQEREKALRLQKEQLQREL---EEKKKKEEQQRLAER 766
E+ R QE E ++ +E+ + Q+E+++ ++ EEK +++E++ +
Sbjct: 815 EKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQE 874
Query: 767 QLQEEQEKKAK 777
+ EQE+K +
Sbjct: 875 EKMREQEEKMR 885
Score = 75.1 bits (183), Expect = 3e-13
Identities = 54/181 (29%), Positives = 98/181 (54%), Gaps = 11/181 (6%)
Query: 606 TEKAKEERLAEEKAKKKAAAK------KMEEVEARRKQEEEARRLRWLQQEEEERRHQEL 659
T K +R EE K++ A + E ++K E +L + E+ E +
Sbjct: 190 TRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVK 249
Query: 660 LQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQE 719
K+K E + L + L Q E R+E+E REQE++ +++ E+ R++ER ++
Sbjct: 250 ELKRKLERAKFLLPQVQTNTL--QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEG 307
Query: 720 RRREQERL--QAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777
+ REQE + E+ L+E+EK LR Q+++L RE +E +++EEQ + E ++ E++EK +
Sbjct: 308 KMREQEEKMWRQEKRLREQEKELREQEKEL-REQKELREQEEQMQEQEEKMWEQEEKMRE 366
Query: 778 E 778
+
Sbjct: 367 Q 367
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 128 bits (322), Expect = 2e-29
Identities = 93/290 (32%), Positives = 171/290 (58%), Gaps = 44/290 (15%)
Query: 529 DPKEKERQRLENLRRKEEA-----EQLRRQKV----EEDKRRRLEEVKLKREERLRKVLQ 579
+ +EK R++ E +RR+EE E++RRQ+ +E+K RR EE+ ++EE++R+
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR--- 381
Query: 580 ARERVEQMKEEKKKQIEQKFAQ---IDEKTEKAKEE-RLAEEKAKKKAAAKKMEEVEARR 635
+E + KEEK +++E+K + I E+ EK +EE ++ E++ +++ AK + E R
Sbjct: 382 -QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 440
Query: 636 KQEEEAR---RLRWLQQE----------EEERRHQELLQKKKEEEQERLRKAAEAKRLAE 682
+QEE+ R + W Q+E EE+R+ QE + +++E+ E+ + +++ E
Sbjct: 441 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHE 500
Query: 683 QREQERREQER--------REQER--REQE----RREQERREQERQLAEQERRREQERLQ 728
Q E+ R+++E+ REQE REQE R+E++ REQE E+E+ EQE++
Sbjct: 501 QEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIW 560
Query: 729 AERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
E + QE+E + Q+E+++ + E+ ++EE+ R E + QE++EK K+
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
Score = 124 bits (312), Expect = 3e-28
Identities = 79/257 (30%), Positives = 161/257 (62%), Gaps = 18/257 (7%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKV--EEDKRRRLEEVKLKREERLRKVLQARERVEQMK 588
KEK ++ E +R++EE + +K+ +E+K R EE ++EE++R+ + E+M
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Query: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
E++K E+K + ++K + +EE++ E++ K +K+ E E +R+++EE + +
Sbjct: 555 EQEKIWEEEKRQEQEDKMWR-QEEKIREQEEKVWRQEEKIREQEEKRQEQEE----KMWK 609
Query: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERR--EQERREQE---- 702
QEE+ R +E +Q+++E+ +E+ K E + + +++E++ EQE + EQE + QE
Sbjct: 610 QEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET 669
Query: 703 --RREQERREQERQLAEQERR-REQERLQAERE--LQEREKALRLQKEQLQRELEEKKKK 757
R+E++ REQE+++ EQE + REQE + E+E + E+E+ + Q+E++Q + E+ +++
Sbjct: 670 MWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 729
Query: 758 EEQQRLAERQLQEEQEK 774
EE+ E +L++++EK
Sbjct: 730 EEKMWEQEVRLRQQEEK 746
Score = 118 bits (296), Expect = 2e-26
Identities = 92/318 (28%), Positives = 179/318 (56%), Gaps = 61/318 (19%)
Query: 520 IKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKV----EEDKRRRLEEVKLKREERLR 575
++R + + +EK R++ E + KEE ++RRQ+ +E+K RR EE+ ++EE++R
Sbjct: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEE--KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 394
Query: 576 KVLQARERVEQMKE-EKKKQIEQKFAQIDEKTEKA-----KEERLAEEKAKKKAAAKKM- 628
++ + E+++E E+K+Q E+K + +++ E+ +EE++ E++ K + KKM
Sbjct: 395 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 454
Query: 629 ------------EEVEARRKQEEEARRLR--------WLQ------QEEEERRHQELLQK 662
E E R++QEE R+ W Q QEE+ R+ +E + +
Sbjct: 455 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWR 514
Query: 663 KKE---EEQERLRKAAE-----AKRLAEQREQERREQERREQE-------RREQE----R 703
++E E++E++R+ E +++ EQ E R E++ EQE R+EQE R
Sbjct: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWR 574
Query: 704 REQERREQERQLAEQE---RRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQ 760
+E++ REQE ++ QE R +E++R + E ++ ++E+ +R Q+E++Q + E+ +++EE+
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634
Query: 761 QRLAERQLQEEQEKKAKE 778
R E QE++EK ++
Sbjct: 635 IREQEEMTQEQEEKMGEQ 652
Score = 116 bits (290), Expect = 1e-25
Identities = 79/263 (30%), Positives = 161/263 (61%), Gaps = 16/263 (6%)
Query: 531 KEKERQRLENLRRKEEA----EQLRRQKV----EEDKRRRLEEVKLKREERLRKVLQA-R 581
+E++RQ E + R+EE E++ RQK +E+K R+ EE ++EE++R+ + R
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
Query: 582 ERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEA 641
E+ E+M +++K EQ+ +E+ + ++E++ EE+ +++ K + E R+QEE+
Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEE-KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKV 586
Query: 642 RRLRWLQQEEEERR--HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 699
R +E+EE+R +E + K++E+ +E+ K E + ++E++ REQE QE+
Sbjct: 587 WRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQE 646
Query: 700 EQERREQERR-EQERQLAEQER---RREQERLQAERELQEREKALRLQKEQLQRELEEKK 755
E+ ++E+ EQE ++ EQE R+E++ + E++++E+E+ +R Q+E +Q + E+
Sbjct: 647 EKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 706
Query: 756 KKEEQQRLAERQLQEEQEKKAKE 778
++EE+ E ++QE++EK ++
Sbjct: 707 EQEEKMCEQEEKMQEQEEKMRRQ 729
Score = 113 bits (283), Expect = 7e-25
Identities = 112/492 (22%), Positives = 237/492 (48%), Gaps = 62/492 (12%)
Query: 318 LAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKE 377
L +K LV ++S ++ + L +K LER + Q++ +E
Sbjct: 226 LQEKLQLVESEKSEIQLNVKELKRK----------------LERAKLLLPQQQLQAEADH 269
Query: 378 PPEEAEPVAAA-EPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQ 436
+E + V+A + +V EN W + + + E Q+E +Q
Sbjct: 270 LGKELQSVSAKLQAQVEENE---LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQ 326
Query: 437 ADGPREPPQSARRK-----------RSYKQAVSELDEEQHLEDE---ELQPPRSKTPSSP 482
+ RE + RR+ R ++ + E +E+ ++E E + +
Sbjct: 327 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 386
Query: 483 CPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRM-DPKEKERQRLENL 541
+ +R L +H ++ + + + ++ +M +EK R++ E +
Sbjct: 387 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 446
Query: 542 RRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKE-EKKKQIEQKFA 600
R +E+ + +K+ E ++ R EE + ++EE R+ + E+ E ++ EK + E+K
Sbjct: 447 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIR 506
Query: 601 QIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQE-- 658
+ +EK + +EE++ E++ K + +KM E + +++EE R EEE+ H++
Sbjct: 507 KQEEKVWR-QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWR-------EEEKMHEQEK 558
Query: 659 -LLQKKKEEEQERLRKAAEAKRLAEQR----EQERREQERREQERREQERREQER-REQE 712
++K++E+++++ + E R E++ E++ REQE + QE+ E+ +++E+ REQE
Sbjct: 559 IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618
Query: 713 RQLAEQERR--------REQERLQAERE--LQEREKALRLQKEQLQRELEEKKKKEEQQR 762
++ EQE + REQE + E+E + E+E+ + Q+E++Q + E ++EE+ R
Sbjct: 619 EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 763 LAERQLQEEQEK 774
E++++E++EK
Sbjct: 679 EQEKKIREQEEK 690
Score = 105 bits (262), Expect = 2e-22
Identities = 73/239 (30%), Positives = 141/239 (58%), Gaps = 17/239 (7%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQM--K 588
+EK R++ E +R +EE + +K+ E + EE K+ +E++ + + +E+ ++M +
Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQ 575
Query: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
EEK ++ E+K + +EK + +E+R +E+ K K E+ E ++QEE+ R +
Sbjct: 576 EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIR-----E 630
Query: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQE--RREQERREQER--REQER- 703
QEE+ R +E+ Q+++E+ E+ K E + +++E+ R+E++ REQE+ REQE
Sbjct: 631 QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEK 690
Query: 704 -REQER--REQERQLAEQERR--REQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
REQE +EQE ++ EQE + ++E++Q + E R++ ++E R+ EEK ++
Sbjct: 691 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 96.7 bits (239), Expect = 9e-20
Identities = 75/280 (26%), Positives = 152/280 (54%), Gaps = 26/280 (9%)
Query: 513 RSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE 572
R + + RNT + KEK + E L+ E + + V+E KR KL+R +
Sbjct: 202 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKR------KLERAK 255
Query: 573 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDE-----KTEKAKEERLAEEKAKKKAAAKK 627
L Q + + + +E + + AQ++E + + +EE++ ++ K + +K
Sbjct: 256 LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK 315
Query: 628 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE----EQERLRKAAEAKRLAEQ 683
++E E + +++EE ++++EE+ R QE + +KEE ++E + + E R E+
Sbjct: 316 IQEQEEKIREQEEK-----IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 370
Query: 684 REQERREQERREQE---RREQERREQERR--EQERQLAEQERRREQERLQAERELQEREK 738
E+ E+ RR++E +E++ RE E + EQE+ ++E+R+E+E+++ + + QE+E
Sbjct: 371 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 430
Query: 739 ALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
+ Q+E++ RE EEK +++E++ + + EQEK +E
Sbjct: 431 KMWRQEEKI-REQEEKIREQEKKMWRQEEKIHEQEKIREE 469
Score = 95.1 bits (235), Expect = 3e-19
Identities = 72/264 (27%), Positives = 145/264 (54%), Gaps = 26/264 (9%)
Query: 531 KEKERQRLENLRRKEEAEQLR--RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK 588
K+K + +E L ++ +A L R + +++ L+E K +E+L+ V + ++
Sbjct: 188 KKKADRYIEELTKERDALSLELYRNTITDEE---LKEKNAKLQEKLQLVESEKSEIQLNV 244
Query: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
+E K+++E+ + ++ +A+ + L +E A +++A+ ++ E RL Q
Sbjct: 245 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA------KLQAQVEENELWNRLNQ-Q 297
Query: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAK-RLAEQREQERREQE--------RREQERR 699
QEE+ R +E +Q+ +E+ QE+ K E + ++ EQ E+ RR++E R QE
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 357
Query: 700 EQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE 759
E+ E+ RR++E ++E+ R QE + E+E + RE ++ +++ RE EEK+++EE
Sbjct: 358 MWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE 417
Query: 760 QQRLAERQLQEE-----QEKKAKE 778
+ R E++ ++E QE+K +E
Sbjct: 418 KIREQEKRQEQEAKMWRQEEKIRE 441
Score = 89.4 bits (220), Expect = 1e-17
Identities = 61/201 (30%), Positives = 120/201 (59%), Gaps = 19/201 (9%)
Query: 527 RMDPKEKERQRLENLRRKEEAEQLRRQKV--EEDKRRRLEEVKLKREERLRKVLQARERV 584
R + ++K ++ E +R +EE + +K+ +E+KR+ EE K+EE++R+ +E
Sbjct: 565 RQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIRE----QEEK 620
Query: 585 EQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 644
Q +EEK ++ E+K + +E T++ +EE++ E++ K +KM+E E ++EE R
Sbjct: 621 IQEQEEKIREQEEKIREQEEMTQE-QEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR- 678
Query: 645 RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR 704
+QE++ R +E +++++E QE+ K E +E++ EQE + QE+ E+ RR
Sbjct: 679 ---EQEKKIREQEEKIREQEEMMQEQEEKMWE-------QEEKMCEQEEKMQEQEEKMRR 728
Query: 705 EQERR-EQERQLAEQERRREQ 724
++E+ EQE +L +QE + ++
Sbjct: 729 QEEKMWEQEVRLRQQEEKMQE 749
Score = 64.3 bits (155), Expect = 5e-10
Identities = 67/281 (23%), Positives = 135/281 (48%), Gaps = 38/281 (13%)
Query: 529 DPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVL-QARERVEQM 587
D ++ Q E LRR+ EA Q+ ++ ++ L+ + ++++ +AR+ + ++
Sbjct: 109 DEQKASHQHQEALRRELEA-QVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAK------KMEEVEARRKQEEEA 641
+ K E + A T+K K +R EE K++ A + + E + K +
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 642 RRLRWLQQEEEE-------------RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER 688
+L+ ++ E+ E R L Q++ + E + L K ++ Q + E
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 287
Query: 689 REQERREQERREQE--RREQERREQERQLAEQERR-REQERLQAERELQEREKALRLQKE 745
E R +++E++ R+E++ +E E ++ EQE + REQE +++E+E+ +R Q+E
Sbjct: 288 NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE-----KIREQEEKMRRQEE 342
Query: 746 QLQRELEEKKK--------KEEQQRLAERQLQEEQEKKAKE 778
+ E EEK + KEE+ R E + E++EK ++
Sbjct: 343 MMW-EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 382
Score = 58.9 bits (141), Expect = 2e-08
Identities = 38/133 (28%), Positives = 78/133 (58%), Gaps = 10/133 (7%)
Query: 529 DPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK 588
+ +EK R++ E +R +EE Q + +K+ E EE ++EE++++ + R E+
Sbjct: 623 EQEEKIREQEEKIREQEEMTQEQEEKMGEQ-----EEKMCEQEEKMQEQEETMWRQEEKI 677
Query: 589 EEKKKQIEQKFAQIDEKTE--KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE---ARR 643
E++K+I ++ +I E+ E + +EE++ E++ K +KM+E E + +++EE +
Sbjct: 678 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737
Query: 644 LRWLQQEEEERRH 656
+R QQEE+ + H
Sbjct: 738 VRLRQQEEKMQEH 750
Score = 48.9 bits (115), Expect = 2e-05
Identities = 31/121 (25%), Positives = 68/121 (56%), Gaps = 10/121 (8%)
Query: 520 IKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQ 579
I+ + + +EK ++ E + +EE + Q+ EE R+ E+++ E+ +K+ +
Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEE----KMQEQEETMWRQEEKIR----EQEKKIRE 686
Query: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
E++ + +E ++Q E+ + Q ++ E +EE++ E++ K + +KM E E R +Q+E
Sbjct: 687 QEEKIREQEEMMQEQEEKMWEQEEKMCE--QEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 744
Query: 640 E 640
E
Sbjct: 745 E 745
Score = 35.4 bits (80), Expect = 0.24
Identities = 36/189 (19%), Positives = 82/189 (43%), Gaps = 13/189 (6%)
Query: 429 QQEAKTDQADGPREPPQSARRK----RSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCP 484
Q++ Q + RE + R+ R ++ E +E+ ++E+++ K
Sbjct: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK 627
Query: 485 ASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRK 544
+ +R Q + M + ++ +EK R++ + +R +
Sbjct: 628 IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQ 687
Query: 545 EEA--EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQI 602
EE EQ + +E+K EE ++EE++ +E+ E+M+ +++K EQ+ ++
Sbjct: 688 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM------QEQEEKMRRQEEKMWEQE-VRL 740
Query: 603 DEKTEKAKE 611
++ EK +E
Sbjct: 741 RQQEEKMQE 749
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 127 bits (318), Expect = 6e-29
Identities = 83/273 (30%), Positives = 170/273 (62%), Gaps = 29/273 (10%)
Query: 529 DPKEKERQRLENLRRKEEA-----EQLRRQKV----EEDKRRRLEEVKLKREERLRKVLQ 579
+ +EK R++ E +RR+EE E++RRQ+ +E+K RR EE+ ++EE++R++ +
Sbjct: 386 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 445
Query: 580 ARERVEQMKE-EKKKQIEQKFAQIDEKTE------------KAKEERLAEEKAKKKAAAK 626
E+++E E+K+Q E+K + +++ E + +EE++ E++ K +
Sbjct: 446 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEE 505
Query: 627 KMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE--EEQERLRKAAEAKRLAEQR 684
K+ E E R++E+ + +QEE+ R +E+ ++K++ E++E++RK E K ++
Sbjct: 506 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEE-KMWRQEE 564
Query: 685 EQERREQERREQERREQERREQERREQERQLAEQERR-REQERLQAERE--LQEREKALR 741
+ +E++ REQE + R+E++ REQE ++ EQE + REQE + E+E + E+E+ +
Sbjct: 565 KMHDQEEKIREQEEKVW-RQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 623
Query: 742 LQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 774
Q+E++Q + E+ +++EE+ R E++++E++EK
Sbjct: 624 EQEEKMQEQEEKMRRQEEKIREQEKKIREQEEK 656
Score = 124 bits (310), Expect = 5e-28
Identities = 83/265 (31%), Positives = 163/265 (61%), Gaps = 27/265 (10%)
Query: 536 QRLENLRRKEE-----AEQLRRQK----VEEDKRRRLEEVKLKREERLRKVLQARERVEQ 586
++ E +RR+EE E++RRQ+ +E+K R LEE K+ +E++R+ + R+ E+
Sbjct: 407 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE-KMHEQEKIREQEEKRQEEEK 465
Query: 587 MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRW 646
++E++K+Q ++ E+ + +EE++ E++ K +K+ E E R++E+ +
Sbjct: 466 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEM 525
Query: 647 LQQEEEERRHQELLQKKKE--EEQERLRKAAEAKRLAEQR----EQERREQE----RREQ 696
+QEE+ R +E+ ++K++ E++E++RK E E++ E++ REQE R+E+
Sbjct: 526 WRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEE 585
Query: 697 ERREQER--REQER--REQERQLAEQERR---REQERLQAERELQEREKALRLQKEQLQR 749
+ REQE REQE REQE EQE + +E++ + E ++QE+E+ +R Q+E+++
Sbjct: 586 KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE 645
Query: 750 ELEEKKKKEEQQRLAERQLQEEQEK 774
+ ++ +++EE+ R E +QE++EK
Sbjct: 646 QEKKIREQEEKIREQEEMMQEQEEK 670
Score = 123 bits (308), Expect = 9e-28
Identities = 81/267 (30%), Positives = 163/267 (61%), Gaps = 23/267 (8%)
Query: 529 DPKEKERQRLENLRRKEEAEQLRRQKV----EEDKRRRLEEVKLKREERLRKVLQARERV 584
+ +EK R++ E +R +EE ++RRQ+ +E+K RR EE+ ++EE++R+ +E +
Sbjct: 379 EQEEKIREQEEKIREQEE--KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR----QEEM 432
Query: 585 EQMKEEKKKQIEQKFAQ---IDEKTEKAKEE-RLAEEKAKKKAAAKKMEEVEARRKQEEE 640
KEEK +++E+K + I E+ EK +EE ++ E++ +++ AK + E R+QEE+
Sbjct: 433 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 492
Query: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER-- 698
R +EE+ H++ +++E+ QE+ + +++ EQ E R++++ EQE
Sbjct: 493 IREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKI 552
Query: 699 REQE----RREQERREQERQLAEQER---RREQERLQAERELQEREKALRLQKEQLQREL 751
R+QE R+E++ +QE ++ EQE R+E++ + E +++E+E+ +R Q+E Q +
Sbjct: 553 RKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQE 612
Query: 752 EEKKKKEEQQRLAERQLQEEQEKKAKE 778
E+ ++EE+ E ++QE++EK ++
Sbjct: 613 EKMGEQEEKMCEQEEKMQEQEEKMRRQ 639
Score = 122 bits (305), Expect = 2e-27
Identities = 83/284 (29%), Positives = 170/284 (59%), Gaps = 25/284 (8%)
Query: 520 IKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQ 579
++R + + +EK R++ E + KEE + +K+ E ++ R +E K + EE++R+ +
Sbjct: 412 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 471
Query: 580 ARERVEQM--KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEV----EA 633
+E+ +M +EEK ++ E+K + +EK + +E+ +EK +++ ++ EE+ E
Sbjct: 472 RQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 531
Query: 634 RRKQEEEARRLRWLQQEEEERRHQE----LLQKKKEEEQERLRKAAE-----AKRLAEQR 684
R+QEE R+ + ++EE+ R QE ++K +++E++R+ E +++ EQ
Sbjct: 532 IREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE 591
Query: 685 EQERREQER-REQERREQERR----EQERR--EQERQLAEQE---RRREQERLQAERELQ 734
E+ R ++E+ REQE QE+ EQE + EQE ++ EQE RR+E++ + E++++
Sbjct: 592 EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIR 651
Query: 735 EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
E+E+ +R Q+E +Q + E+ ++EE+ E ++QE++EK ++
Sbjct: 652 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 695
Score = 120 bits (301), Expect = 6e-27
Identities = 107/463 (23%), Positives = 229/463 (49%), Gaps = 38/463 (8%)
Query: 318 LAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKE 377
L +K LV ++S ++ + L +K LER + Q++ +E
Sbjct: 287 LQEKLQLVESEKSEIQLNVKELKRK----------------LERAKLLLPQQQLQAEADH 330
Query: 378 PPEEAEPVAAA-EPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQ 436
+E + V+A + +V EN W + + + E Q+E +Q
Sbjct: 331 LGKELQSVSAKLQAQVEENE---LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQ 387
Query: 437 ADGPREPPQSARRKRSYKQAVSELDEEQHLEDE---ELQPPRSKTPSSPCPASKVVRPLR 493
+ RE + RR+ ++ + E +E+ ++E E + + + +R L
Sbjct: 388 EEKIREQEEKMRRQ---EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 444
Query: 494 TFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRM-DPKEKERQRLENLRRKEEAEQLRR 552
+H ++ + + + ++ +M +EK R++ E +R +EE +
Sbjct: 445 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQE 504
Query: 553 QKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKK-KQIEQKFAQIDEKTEKAKE 611
+K+ E ++ R EE + ++EE R+ + RE+ E ++++K + E+K + +EK + +E
Sbjct: 505 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEE 564
Query: 612 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERL 671
+ +E+ ++ K + E R+QEE+ R +QEE+ R +E+ Q+++E+ E+
Sbjct: 565 KMHDQEEKIREQEEKVWRQEEKIREQEEKIR-----EQEEKIREQEEMTQEQEEKMGEQE 619
Query: 672 RKAAEAKRLAEQREQERREQERREQER-REQERREQERREQERQLAEQERRREQERLQAE 730
K E E++ QE+ E+ RR++E+ REQE++ +E+ E+ R+ E + +E++ + E
Sbjct: 620 EKMCEQ----EEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 675
Query: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE 773
++ E+E+ ++ Q+E+++R+ E+ ++E + R E ++QE QE
Sbjct: 676 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 116 bits (291), Expect = 8e-26
Identities = 80/261 (30%), Positives = 162/261 (62%), Gaps = 21/261 (8%)
Query: 531 KEKERQRLENLRRKEE-AEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKE 589
+E++RQ E +R +E+ EQ + +E+K R EE ++EE++ + + E+++E
Sbjct: 456 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE 515
Query: 590 EKKKQIEQKFAQIDEKTEKAKE-----ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 644
E+K+Q +++ + +EK + +E E++ E++ K + +KM E + +EE R
Sbjct: 516 EEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIR- 574
Query: 645 RWLQQEEEERRHQELLQKKKE---EEQERLRKAAEAKRLAEQR--EQERR--EQERREQE 697
+QEE+ R +E +++++E E++E++R+ E + E++ EQE + EQE + QE
Sbjct: 575 ---EQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 631
Query: 698 RREQERREQER-REQERQLAEQERR-REQERLQAERE--LQEREKALRLQKEQLQRELEE 753
+ E+ RR++E+ REQE+++ EQE + REQE + E+E + E+E+ + Q+E++Q + E+
Sbjct: 632 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 691
Query: 754 KKKKEEQQRLAERQLQEEQEK 774
+++EE+ E +L++++EK
Sbjct: 692 MRRQEEKMWEQEVRLRQQEEK 712
Score = 114 bits (285), Expect = 4e-25
Identities = 87/299 (29%), Positives = 166/299 (55%), Gaps = 39/299 (13%)
Query: 513 RSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL---- 568
R + + RNT + KEK + E L+ E + + V+E KR+ LE KL
Sbjct: 263 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRK-LERAKLLLPQ 321
Query: 569 -----------KREERLRKVLQAR-------ERVEQMKEEKKKQIEQKFAQIDEKTEKAK 610
K + + LQA+ R+ Q +EEK + E+K + +EK ++ +
Sbjct: 322 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE-Q 380
Query: 611 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARR----LRWLQQEEEERRHQELLQKKKEE 666
EE++ E++ K + +KM E ++EE R + W ++EE+ RR +E++ +K+E+
Sbjct: 381 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW-EKEEKMRRQEEMMWEKEEK 439
Query: 667 EQERLRKAAEAKRLAEQREQERREQERREQERREQE-----RREQERREQERQLAEQERR 721
+E K E +++ EQ E+ + E++ REQE+R+++ R+E++ REQE ++ EQE +
Sbjct: 440 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEK 499
Query: 722 --REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
R++E++ + +++E EK R ++E++ R+ E+ +++EE R E+ + E++EK K+
Sbjct: 500 MWRQEEKIHEQEKIREEEK--RQEQEEMWRQEEKIREQEEIWRQKEK-IHEQEEKIRKQ 555
Score = 111 bits (277), Expect = 4e-24
Identities = 79/248 (31%), Positives = 147/248 (59%), Gaps = 26/248 (10%)
Query: 535 RQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 594
+Q+ E + R+EE Q +K++E + + E+ EE++R+ + R E+M EK+++
Sbjct: 357 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQ-----EEKIREQEEKMRRQEEMMWEKEEK 411
Query: 595 IEQKFAQIDEKTEKAK--EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE 652
+ ++ + EK EK + EE + E++ K + +KM E E R+QEE+ +QEEE
Sbjct: 412 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK-------RQEEE 464
Query: 653 ERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE---RREQERREQE--RREQE 707
+ R QE K +EQE + + +++ EQ E+ R ++E R+E++ EQE R E++
Sbjct: 465 KIREQE-----KRQEQE-AKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEK 518
Query: 708 RREQERQLAEQERRREQERLQAERE-LQEREKALRLQKEQLQRELEEKKKKEEQQRLAER 766
R+EQE ++E+ REQE + ++E + E+E+ +R Q+E++ R+ E+ +EE+ R E
Sbjct: 519 RQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEE 578
Query: 767 QLQEEQEK 774
++ ++EK
Sbjct: 579 KVWRQEEK 586
Score = 85.9 bits (211), Expect = 2e-16
Identities = 66/251 (26%), Positives = 134/251 (53%), Gaps = 32/251 (12%)
Query: 531 KEKERQRLENLRRKEEAEQLR--RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK 588
K+K + +E L ++ +A L R + +++ L+E K +E+L+ V + ++
Sbjct: 249 KKKADRYIEELTKERDALSLELYRNTITDEE---LKEKNAKLQEKLQLVESEKSEIQLNV 305
Query: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
+E K+++E+ + ++ +A+ + L +E A +++A+ ++ E RL Q
Sbjct: 306 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA------KLQAQVEENELWNRLNQ-Q 358
Query: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQER 708
QEE+ R +E +Q+ +E+ QE+ E++ REQE + +E+ E+ R
Sbjct: 359 QEEKMWRQEEKIQEWEEKIQEQ-------------------EEKIREQEEKIREQEEKMR 399
Query: 709 REQERQLAEQERRREQERLQAER-ELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQ 767
R++E ++E+ R QE + E+ E R++ + +KE+ RELEEK ++E+ R E +
Sbjct: 400 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 459
Query: 768 LQEEQEKKAKE 778
QEE++ + +E
Sbjct: 460 RQEEEKIREQE 470
Score = 65.5 bits (158), Expect = 2e-10
Identities = 48/158 (30%), Positives = 92/158 (58%), Gaps = 14/158 (8%)
Query: 529 DPKEKERQRLENLRRKEEAEQLRRQKV--EEDKRRRLEEVKLKREERL----RKVLQARE 582
D +EK R++ E + R+EE + + +K+ +E+K R EE+ ++EE++ K+ + E
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 627
Query: 583 RVEQMKEEKKKQ---IEQKFAQIDEKTEKAKE--ERLAEEKAKKKAAAKKM-EEVEARRK 636
++++ +E+ ++Q I ++ +I E+ EK +E E + E++ K +KM E+ E ++
Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687
Query: 637 QEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKA 674
QEE+ RR E+E R Q+ ++K +E QE L A
Sbjct: 688 QEEKMRRQEEKMWEQEVRLRQQ--EEKMQEHQEHLEAA 723
Score = 63.5 bits (153), Expect = 8e-10
Identities = 67/277 (24%), Positives = 133/277 (48%), Gaps = 38/277 (13%)
Query: 529 DPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVL-QARERVEQM 587
D ++ Q E LRR+ EA Q+ ++ ++ L+ + ++++ +AR+ + ++
Sbjct: 170 DEQKASHQHQEALRRELEA-QVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 228
Query: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAK------KMEEVEARRKQEEEA 641
+ K E + A T+K K +R EE K++ A + + E + K +
Sbjct: 229 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 288
Query: 642 RRLRWLQQEEEE-------------RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER 688
+L+ ++ E+ E R L Q++ + E + L K ++ Q + E
Sbjct: 289 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 348
Query: 689 REQERREQERREQE--RREQERREQERQLAEQERR-REQERLQAERELQEREKALRLQKE 745
E R +++E++ R+E++ +E E ++ EQE + REQE +++E+E+ +R Q+E
Sbjct: 349 NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE-----KIREQEEKMRRQEE 403
Query: 746 QLQRELEEKKK--------KEEQQRLAERQLQEEQEK 774
+ E EEK + KEE+ R E + E++EK
Sbjct: 404 MMW-EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 439
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
Length = 1293
Score = 120 bits (301), Expect = 6e-27
Identities = 95/306 (31%), Positives = 164/306 (53%), Gaps = 36/306 (11%)
Query: 521 KRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV-KLKREERLRKVLQ 579
+R +R +E+ER+R E LRR++E E LRRQ+ EE KRR EE+ + K+EE LR+ +
Sbjct: 735 RREAEMRAKREEEERKRQEELRRQQE-EILRRQQEEERKRREEEELARRKQEEALRRQRE 793
Query: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
+ + +EE+++Q Q +E + +E R EE+ +K + E RKQEE
Sbjct: 794 QEIALRRQREEEERQ------QQEEALRRLEERRREEEERRK--------QEELLRKQEE 839
Query: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 699
EA +W ++EEE +R E + + EEE RLR E ++ E Q ++E R+ Q+++
Sbjct: 840 EA--AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ 897
Query: 700 EQERREQERREQERQLAE----------QERRREQERLQAERELQEREKALRLQKEQLQR 749
E RR Q+ ++Q++QLA+ Q+ + QA L E +K L ++E+ R
Sbjct: 898 EALRRLQQ-QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQK-LEEERERQLR 955
Query: 750 ELEEKKKKEEQQRLAERQLQEEQEK-----KAKEAAGASKALNVTVDVQSPACTSYQMTP 804
E E+++++ E + ++Q Q++Q+K + +G +K+L ++ Q
Sbjct: 956 E-EQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1014
Query: 805 QGHRAP 810
Q H+ P
Sbjct: 1015 QQHQQP 1020
Score = 115 bits (288), Expect = 2e-25
Identities = 87/291 (29%), Positives = 157/291 (53%), Gaps = 32/291 (10%)
Query: 506 MTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEE 565
+ PT++ +V + + PL ++L+ L K +A +L +++ E + R + EE
Sbjct: 688 LQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLE-KAKAAKLEQERREAEMRAKREE 746
Query: 566 VKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAA 625
+ KR+E LR+ Q E + + +EE++K+ E+ E+ + K+E + +++ A
Sbjct: 747 EERKRQEELRR--QQEEILRRQQEEERKRREE------EELARRKQEEALRRQREQEIAL 798
Query: 626 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE----------------EQE 669
++ E E R++QEE RRL ++EEEERR QE L +K+EE E+
Sbjct: 799 RRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEEN 858
Query: 670 RLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRRE--QERL 727
RLR EA RL + E+ER+ +E Q ++E R+ Q+++E R+L +Q+++++ Q +L
Sbjct: 859 RLRMEEEAARLRHE-EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 917
Query: 728 QAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
+ ++ Q Q L E +K EE++ ERQL+EEQ ++ +E
Sbjct: 918 PSSSTWGQQSNTTACQ-SQATLSLAEIQKLEEER---ERQLREEQRRQQRE 964
Score = 81.6 bits (200), Expect = 3e-15
Identities = 48/133 (36%), Positives = 85/133 (63%), Gaps = 11/133 (8%)
Query: 660 LQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER--REQERREQERREQERQLAE 717
L+K K + E+ R+ AE + E+ E++R+E+ RR+QE R Q+ E++RRE+E E
Sbjct: 723 LEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE----E 778
Query: 718 QERRREQERLQAERELQ-----EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ 772
RR+++E L+ +RE + +RE+ R Q+E+ R LEE++++EE++R E L++++
Sbjct: 779 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 838
Query: 773 EKKAKEAAGASKA 785
E+ AK A +A
Sbjct: 839 EEAAKWAREEEEA 851
Score = 65.9 bits (159), Expect = 2e-10
Identities = 112/531 (21%), Positives = 205/531 (38%), Gaps = 97/531 (18%)
Query: 287 PDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEE 346
PD + G +TD V S P + S S QE+ + R+ KT +
Sbjct: 342 PDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEA--SQFERKDEPKTEQT 399
Query: 347 PAASGRIICHSYLERLLNVEVPQKVGSEQ---------KEPPEEAEPVAAAEPEVPENNG 397
A + +E L +VP + G E + P + A P+ P VP
Sbjct: 400 EKAEEE----TRMENSLPAKVPSR-GDEMVADVQQPLSQIPSDTASPLLILPPPVP---- 450
Query: 398 NNSWPHNDTEIANSTPNPKPAASSPETP-----SAGQQEAKTDQADGPREPPQSARRKRS 452
NP P ETP G + D +G + Q A + +
Sbjct: 451 ----------------NPSPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVA 494
Query: 453 YKQAVSELDEEQHLEDEELQPPRSKTPSSPC------------PASKVVRPLRTFLHTVQ 500
Y Q S LD+E+ +LQ R+K S P P ++ P
Sbjct: 495 YLQD-SALDDERLAS--KLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFN------- 544
Query: 501 RNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKR 560
NQ + A M +KR ++ Q L ++ +
Sbjct: 545 -NQEMAEWFQAGYFTMSLLVKRAC-------DESFQPLGDIMKMWGRVPFSPGPAPPPHM 596
Query: 561 RRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK 620
L++ +L R++ L + Q Q + ++ I+Q++AQ+ A++++ A +
Sbjct: 597 GELDQERLTRQQELTALYQM-----QHLQYQQFLIQQQYAQV-----LAQQQKAALSSQQ 646
Query: 621 KKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER---------- 670
++ A +++ + + + + + + + + + + Q
Sbjct: 647 QQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDL 706
Query: 671 -LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQA 729
L L + ++ E+ + + EQERRE E R + R E+ER+ E+ RR+++E L
Sbjct: 707 PLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAK-REEEERKRQEELRRQQEEIL-- 763
Query: 730 ERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA-ERQLQEEQEKKAKEA 779
R QE E+ R ++E +R+ EE +++ +Q +A RQ +EE+ ++ +EA
Sbjct: 764 -RRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEA 813
Score = 61.6 bits (148), Expect = 3e-09
Identities = 78/375 (20%), Positives = 163/375 (43%), Gaps = 70/375 (18%)
Query: 381 EAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPK-PAASSPETPSAGQQEAKTDQAD- 438
E +P A+ +P V E G + W D + +TP P E A + E + +A+
Sbjct: 687 ELQPTAS-QPTVWE--GGSVW---DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEM 740
Query: 439 -GPREPPQSARR---KRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRT 494
RE + R+ +R ++ + EE+ EE + R K + + LR
Sbjct: 741 RAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRR 800
Query: 495 FLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQK 554
+R Q + ++R R + E+ER++ E L RK+E E + +
Sbjct: 801 QREEEERQQQ------------EEALRRLEERRRE--EEERRKQEELLRKQEEEAAKWAR 846
Query: 555 VEEDKRRRLEEVKLK-----------REERLRKVLQARERVEQMKEEKKKQIEQKFAQID 603
EE+ +RRLEE +L+ EER RK L+ + + E M++ +++Q + Q
Sbjct: 847 EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 906
Query: 604 EKTEKAKEERL-----------------------AEEKAKKKAAAKKMEEVEARRKQEEE 640
++ ++ + +L AE + ++ +++ E + R+++E
Sbjct: 907 QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE-- 964
Query: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
++ LQQ+++++ Q+K + + K L E +++E R+ ++++Q++++
Sbjct: 965 --LMKALQQQQQQQ------QQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1016
Query: 701 QERREQERREQERQL 715
++ + R L
Sbjct: 1017 HQQPNRARNNTHSNL 1031
Score = 34.3 bits (77), Expect = 0.54
Identities = 21/93 (22%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
Query: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730
L +EAK A+Q ERR +++ Q+R++Q+ +Q++++ +Q +Q ++++
Sbjct: 1172 LGDTSEAKEFAKQF-LERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNH 1230
Query: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRL 763
L + + +Q E + KK+++Q++
Sbjct: 1231 STLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKM 1263
Score = 32.3 bits (72), Expect = 2.1
Identities = 35/168 (20%), Positives = 73/168 (43%), Gaps = 14/168 (8%)
Query: 17 QKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQD 76
+K E L + + W E +EEA+R + E + ++ RK++ + VQ
Sbjct: 828 RKQEELLRKQEEEAAKWARE-EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELE-VQ- 884
Query: 77 ENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATM 136
R++ R+ + Q + RRL+ + ++LA + + S + + A + AT+
Sbjct: 885 ------RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 938
Query: 137 ALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAEQHVT 184
+LA E L + E Q +L+ ++ ++Q +Q ++
Sbjct: 939 SLAEIQKLEEERERQL--REEQRRQQRELMKALQ---QQQQQQQQKLS 981
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 120 bits (301), Expect = 6e-27
Identities = 95/306 (31%), Positives = 164/306 (53%), Gaps = 36/306 (11%)
Query: 521 KRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV-KLKREERLRKVLQ 579
+R +R +E+ER+R E LRR++E E LRRQ+ EE KRR EE+ + K+EE LR+ +
Sbjct: 762 RREAEMRAKREEEERKRQEELRRQQE-EILRRQQEEERKRREEEELARRKQEEALRRQRE 820
Query: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
+ + +EE+++Q Q +E + +E R EE+ +K + E RKQEE
Sbjct: 821 QEIALRRQREEEERQ------QQEEALRRLEERRREEEERRK--------QEELLRKQEE 866
Query: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 699
EA +W ++EEE +R E + + EEE RLR E ++ E Q ++E R+ Q+++
Sbjct: 867 EA--AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ 924
Query: 700 EQERREQERREQERQLAE----------QERRREQERLQAERELQEREKALRLQKEQLQR 749
E RR Q+ ++Q++QLA+ Q+ + QA L E +K L ++E+ R
Sbjct: 925 EALRRLQQ-QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQK-LEEERERQLR 982
Query: 750 ELEEKKKKEEQQRLAERQLQEEQEK-----KAKEAAGASKALNVTVDVQSPACTSYQMTP 804
E E+++++ E + ++Q Q++Q+K + +G +K+L ++ Q
Sbjct: 983 E-EQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1041
Query: 805 QGHRAP 810
Q H+ P
Sbjct: 1042 QQHQQP 1047
Score = 115 bits (288), Expect = 2e-25
Identities = 87/291 (29%), Positives = 157/291 (53%), Gaps = 32/291 (10%)
Query: 506 MTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEE 565
+ PT++ +V + + PL ++L+ L K +A +L +++ E + R + EE
Sbjct: 715 LQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLE-KAKAAKLEQERREAEMRAKREE 773
Query: 566 VKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAA 625
+ KR+E LR+ Q E + + +EE++K+ E+ E+ + K+E + +++ A
Sbjct: 774 EERKRQEELRR--QQEEILRRQQEEERKRREE------EELARRKQEEALRRQREQEIAL 825
Query: 626 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE----------------EQE 669
++ E E R++QEE RRL ++EEEERR QE L +K+EE E+
Sbjct: 826 RRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEEN 885
Query: 670 RLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRRE--QERL 727
RLR EA RL + E+ER+ +E Q ++E R+ Q+++E R+L +Q+++++ Q +L
Sbjct: 886 RLRMEEEAARLRHE-EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 944
Query: 728 QAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
+ ++ Q Q L E +K EE++ ERQL+EEQ ++ +E
Sbjct: 945 PSSSTWGQQSNTTACQ-SQATLSLAEIQKLEEER---ERQLREEQRRQQRE 991
Score = 81.6 bits (200), Expect = 3e-15
Identities = 48/133 (36%), Positives = 85/133 (63%), Gaps = 11/133 (8%)
Query: 660 LQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER--REQERREQERREQERQLAE 717
L+K K + E+ R+ AE + E+ E++R+E+ RR+QE R Q+ E++RRE+E E
Sbjct: 750 LEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE----E 805
Query: 718 QERRREQERLQAERELQ-----EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ 772
RR+++E L+ +RE + +RE+ R Q+E+ R LEE++++EE++R E L++++
Sbjct: 806 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 865
Query: 773 EKKAKEAAGASKA 785
E+ AK A +A
Sbjct: 866 EEAAKWAREEEEA 878
Score = 63.2 bits (152), Expect = 1e-09
Identities = 85/396 (21%), Positives = 164/396 (41%), Gaps = 61/396 (15%)
Query: 413 PNPKPAASSPETP-----SAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLE 467
PNP P ETP G + D +G + Q A + +Y Q S LD+E+
Sbjct: 477 PNPSPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVAYLQD-SALDDERLAS 535
Query: 468 DEELQPPRSKTPSSPC------------PASKVVRPLRTFLHTVQRNQMLMTPTSAPRSV 515
+LQ R+K S P P ++ P NQ + A
Sbjct: 536 --KLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFN--------NQEMAEWFQAGYFT 585
Query: 516 MKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR 575
M +KR ++ Q L ++ + L++ +L R++ L
Sbjct: 586 MSLLVKRAC-------DESFQPLGDIMKMWGRVPFSPGPAPPPHMGELDQERLTRQQELT 638
Query: 576 KVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARR 635
+ Q Q + ++ I+Q++AQ+ A++++ A +++ A +++ + +
Sbjct: 639 ALYQM-----QHLQYQQFLIQQQYAQV-----LAQQQKAALSSQQQQQLALLLQQFQTLK 688
Query: 636 KQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER-----------LRKAAEAKRLAEQR 684
+ + + + + + + + Q L L + +
Sbjct: 689 MRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQ 748
Query: 685 EQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 744
+ E+ + + EQERRE E R + R E+ER+ E+ RR+++E L R QE E+ R ++
Sbjct: 749 QLEKAKAAKLEQERREAEMRAK-REEEERKRQEELRRQQEEIL---RRQQEEERKRREEE 804
Query: 745 EQLQRELEEKKKKEEQQRLA-ERQLQEEQEKKAKEA 779
E +R+ EE +++ +Q +A RQ +EE+ ++ +EA
Sbjct: 805 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEA 840
Score = 61.6 bits (148), Expect = 3e-09
Identities = 78/375 (20%), Positives = 163/375 (43%), Gaps = 70/375 (18%)
Query: 381 EAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPK-PAASSPETPSAGQQEAKTDQAD- 438
E +P A+ +P V E G + W D + +TP P E A + E + +A+
Sbjct: 714 ELQPTAS-QPTVWE--GGSVW---DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEM 767
Query: 439 -GPREPPQSARR---KRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRT 494
RE + R+ +R ++ + EE+ EE + R K + + LR
Sbjct: 768 RAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRR 827
Query: 495 FLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQK 554
+R Q + ++R R + E+ER++ E L RK+E E + +
Sbjct: 828 QREEEERQQQ------------EEALRRLEERRRE--EEERRKQEELLRKQEEEAAKWAR 873
Query: 555 VEEDKRRRLEEVKLK-----------REERLRKVLQARERVEQMKEEKKKQIEQKFAQID 603
EE+ +RRLEE +L+ EER RK L+ + + E M++ +++Q + Q
Sbjct: 874 EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 933
Query: 604 EKTEKAKEERL-----------------------AEEKAKKKAAAKKMEEVEARRKQEEE 640
++ ++ + +L AE + ++ +++ E + R+++E
Sbjct: 934 QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE-- 991
Query: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
++ LQQ+++++ Q+K + + K L E +++E R+ ++++Q++++
Sbjct: 992 --LMKALQQQQQQQ------QQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1043
Query: 701 QERREQERREQERQL 715
++ + R L
Sbjct: 1044 HQQPNRARNNTHSNL 1058
Score = 34.3 bits (77), Expect = 0.54
Identities = 21/93 (22%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
Query: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730
L +EAK A+Q ERR +++ Q+R++Q+ +Q++++ +Q +Q ++++
Sbjct: 1199 LGDTSEAKEFAKQF-LERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNH 1257
Query: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRL 763
L + + +Q E + KK+++Q++
Sbjct: 1258 STLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKM 1290
Score = 32.3 bits (72), Expect = 2.1
Identities = 35/168 (20%), Positives = 73/168 (43%), Gaps = 14/168 (8%)
Query: 17 QKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQD 76
+K E L + + W E +EEA+R + E + ++ RK++ + VQ
Sbjct: 855 RKQEELLRKQEEEAAKWARE-EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELE-VQ- 911
Query: 77 ENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATM 136
R++ R+ + Q + RRL+ + ++LA + + S + + A + AT+
Sbjct: 912 ------RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 965
Query: 137 ALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAEQHVT 184
+LA E L + E Q +L+ ++ ++Q +Q ++
Sbjct: 966 SLAEIQKLEEERERQL--REEQRRQQRELMKALQ---QQQQQQQQKLS 1008
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 120 bits (301), Expect = 6e-27
Identities = 95/306 (31%), Positives = 164/306 (53%), Gaps = 36/306 (11%)
Query: 521 KRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV-KLKREERLRKVLQ 579
+R +R +E+ER+R E LRR++E E LRRQ+ EE KRR EE+ + K+EE LR+ +
Sbjct: 741 RREAEMRAKREEEERKRQEELRRQQE-EILRRQQEEERKRREEEELARRKQEEALRRQRE 799
Query: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
+ + +EE+++Q Q +E + +E R EE+ +K + E RKQEE
Sbjct: 800 QEIALRRQREEEERQ------QQEEALRRLEERRREEEERRK--------QEELLRKQEE 845
Query: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 699
EA +W ++EEE +R E + + EEE RLR E ++ E Q ++E R+ Q+++
Sbjct: 846 EA--AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ 903
Query: 700 EQERREQERREQERQLAE----------QERRREQERLQAERELQEREKALRLQKEQLQR 749
E RR Q+ ++Q++QLA+ Q+ + QA L E +K L ++E+ R
Sbjct: 904 EALRRLQQ-QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQK-LEEERERQLR 961
Query: 750 ELEEKKKKEEQQRLAERQLQEEQEK-----KAKEAAGASKALNVTVDVQSPACTSYQMTP 804
E E+++++ E + ++Q Q++Q+K + +G +K+L ++ Q
Sbjct: 962 E-EQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
Query: 805 QGHRAP 810
Q H+ P
Sbjct: 1021 QQHQQP 1026
Score = 115 bits (288), Expect = 2e-25
Identities = 87/291 (29%), Positives = 157/291 (53%), Gaps = 32/291 (10%)
Query: 506 MTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEE 565
+ PT++ +V + + PL ++L+ L K +A +L +++ E + R + EE
Sbjct: 694 LQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLE-KAKAAKLEQERREAEMRAKREE 752
Query: 566 VKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAA 625
+ KR+E LR+ Q E + + +EE++K+ E+ E+ + K+E + +++ A
Sbjct: 753 EERKRQEELRR--QQEEILRRQQEEERKRREE------EELARRKQEEALRRQREQEIAL 804
Query: 626 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE----------------EQE 669
++ E E R++QEE RRL ++EEEERR QE L +K+EE E+
Sbjct: 805 RRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEEN 864
Query: 670 RLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRRE--QERL 727
RLR EA RL + E+ER+ +E Q ++E R+ Q+++E R+L +Q+++++ Q +L
Sbjct: 865 RLRMEEEAARLRHE-EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 923
Query: 728 QAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
+ ++ Q Q L E +K EE++ ERQL+EEQ ++ +E
Sbjct: 924 PSSSTWGQQSNTTACQ-SQATLSLAEIQKLEEER---ERQLREEQRRQQRE 970
Score = 81.6 bits (200), Expect = 3e-15
Identities = 48/133 (36%), Positives = 85/133 (63%), Gaps = 11/133 (8%)
Query: 660 LQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER--REQERREQERREQERQLAE 717
L+K K + E+ R+ AE + E+ E++R+E+ RR+QE R Q+ E++RRE+E E
Sbjct: 729 LEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE----E 784
Query: 718 QERRREQERLQAERELQ-----EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ 772
RR+++E L+ +RE + +RE+ R Q+E+ R LEE++++EE++R E L++++
Sbjct: 785 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 844
Query: 773 EKKAKEAAGASKA 785
E+ AK A +A
Sbjct: 845 EEAAKWAREEEEA 857
Score = 65.9 bits (159), Expect = 2e-10
Identities = 112/531 (21%), Positives = 205/531 (38%), Gaps = 97/531 (18%)
Query: 287 PDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEE 346
PD + G +TD V S P + S S QE+ + R+ KT +
Sbjct: 348 PDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEA--SQFERKDEPKTEQT 405
Query: 347 PAASGRIICHSYLERLLNVEVPQKVGSEQ---------KEPPEEAEPVAAAEPEVPENNG 397
A + +E L +VP + G E + P + A P+ P VP
Sbjct: 406 EKAEEE----TRMENSLPAKVPSR-GDEMVADVQQPLSQIPSDTASPLLILPPPVP---- 456
Query: 398 NNSWPHNDTEIANSTPNPKPAASSPETP-----SAGQQEAKTDQADGPREPPQSARRKRS 452
NP P ETP G + D +G + Q A + +
Sbjct: 457 ----------------NPSPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVA 500
Query: 453 YKQAVSELDEEQHLEDEELQPPRSKTPSSPC------------PASKVVRPLRTFLHTVQ 500
Y Q S LD+E+ +LQ R+K S P P ++ P
Sbjct: 501 YLQD-SALDDERLAS--KLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFN------- 550
Query: 501 RNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKR 560
NQ + A M +KR ++ Q L ++ +
Sbjct: 551 -NQEMAEWFQAGYFTMSLLVKRAC-------DESFQPLGDIMKMWGRVPFSPGPAPPPHM 602
Query: 561 RRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK 620
L++ +L R++ L + Q Q + ++ I+Q++AQ+ A++++ A +
Sbjct: 603 GELDQERLTRQQELTALYQM-----QHLQYQQFLIQQQYAQV-----LAQQQKAALSSQQ 652
Query: 621 KKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER---------- 670
++ A +++ + + + + + + + + + + Q
Sbjct: 653 QQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDL 712
Query: 671 -LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQA 729
L L + ++ E+ + + EQERRE E R + R E+ER+ E+ RR+++E L
Sbjct: 713 PLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAK-REEEERKRQEELRRQQEEIL-- 769
Query: 730 ERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA-ERQLQEEQEKKAKEA 779
R QE E+ R ++E +R+ EE +++ +Q +A RQ +EE+ ++ +EA
Sbjct: 770 -RRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEA 819
Score = 61.6 bits (148), Expect = 3e-09
Identities = 78/375 (20%), Positives = 163/375 (43%), Gaps = 70/375 (18%)
Query: 381 EAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPK-PAASSPETPSAGQQEAKTDQAD- 438
E +P A+ +P V E G + W D + +TP P E A + E + +A+
Sbjct: 693 ELQPTAS-QPTVWE--GGSVW---DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEM 746
Query: 439 -GPREPPQSARR---KRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRT 494
RE + R+ +R ++ + EE+ EE + R K + + LR
Sbjct: 747 RAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRR 806
Query: 495 FLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQK 554
+R Q + ++R R + E+ER++ E L RK+E E + +
Sbjct: 807 QREEEERQQQ------------EEALRRLEERRRE--EEERRKQEELLRKQEEEAAKWAR 852
Query: 555 VEEDKRRRLEEVKLK-----------REERLRKVLQARERVEQMKEEKKKQIEQKFAQID 603
EE+ +RRLEE +L+ EER RK L+ + + E M++ +++Q + Q
Sbjct: 853 EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 912
Query: 604 EKTEKAKEERL-----------------------AEEKAKKKAAAKKMEEVEARRKQEEE 640
++ ++ + +L AE + ++ +++ E + R+++E
Sbjct: 913 QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE-- 970
Query: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
++ LQQ+++++ Q+K + + K L E +++E R+ ++++Q++++
Sbjct: 971 --LMKALQQQQQQQ------QQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1022
Query: 701 QERREQERREQERQL 715
++ + R L
Sbjct: 1023 HQQPNRARNNTHSNL 1037
Score = 34.3 bits (77), Expect = 0.54
Identities = 21/93 (22%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
Query: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730
L +EAK A+Q ERR +++ Q+R++Q+ +Q++++ +Q +Q ++++
Sbjct: 1178 LGDTSEAKEFAKQF-LERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNH 1236
Query: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRL 763
L + + +Q E + KK+++Q++
Sbjct: 1237 STLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKM 1269
Score = 32.3 bits (72), Expect = 2.1
Identities = 35/168 (20%), Positives = 73/168 (43%), Gaps = 14/168 (8%)
Query: 17 QKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQD 76
+K E L + + W E +EEA+R + E + ++ RK++ + VQ
Sbjct: 834 RKQEELLRKQEEEAAKWARE-EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELE-VQ- 890
Query: 77 ENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATM 136
R++ R+ + Q + RRL+ + ++LA + + S + + A + AT+
Sbjct: 891 ------RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 944
Query: 137 ALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAEQHVT 184
+LA E L + E Q +L+ ++ ++Q +Q ++
Sbjct: 945 SLAEIQKLEEERERQL--REEQRRQQRELMKALQ---QQQQQQQQKLS 987
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 120 bits (301), Expect = 6e-27
Identities = 95/306 (31%), Positives = 164/306 (53%), Gaps = 36/306 (11%)
Query: 521 KRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV-KLKREERLRKVLQ 579
+R +R +E+ER+R E LRR++E E LRRQ+ EE KRR EE+ + K+EE LR+ +
Sbjct: 741 RREAEMRAKREEEERKRQEELRRQQE-EILRRQQEEERKRREEEELARRKQEEALRRQRE 799
Query: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
+ + +EE+++Q Q +E + +E R EE+ +K + E RKQEE
Sbjct: 800 QEIALRRQREEEERQ------QQEEALRRLEERRREEEERRK--------QEELLRKQEE 845
Query: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 699
EA +W ++EEE +R E + + EEE RLR E ++ E Q ++E R+ Q+++
Sbjct: 846 EA--AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ 903
Query: 700 EQERREQERREQERQLAE----------QERRREQERLQAERELQEREKALRLQKEQLQR 749
E RR Q+ ++Q++QLA+ Q+ + QA L E +K L ++E+ R
Sbjct: 904 EALRRLQQ-QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQK-LEEERERQLR 961
Query: 750 ELEEKKKKEEQQRLAERQLQEEQEK-----KAKEAAGASKALNVTVDVQSPACTSYQMTP 804
E E+++++ E + ++Q Q++Q+K + +G +K+L ++ Q
Sbjct: 962 E-EQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
Query: 805 QGHRAP 810
Q H+ P
Sbjct: 1021 QQHQQP 1026
Score = 115 bits (288), Expect = 2e-25
Identities = 87/291 (29%), Positives = 157/291 (53%), Gaps = 32/291 (10%)
Query: 506 MTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEE 565
+ PT++ +V + + PL ++L+ L K +A +L +++ E + R + EE
Sbjct: 694 LQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLE-KAKAAKLEQERREAEMRAKREE 752
Query: 566 VKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAA 625
+ KR+E LR+ Q E + + +EE++K+ E+ E+ + K+E + +++ A
Sbjct: 753 EERKRQEELRR--QQEEILRRQQEEERKRREE------EELARRKQEEALRRQREQEIAL 804
Query: 626 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE----------------EQE 669
++ E E R++QEE RRL ++EEEERR QE L +K+EE E+
Sbjct: 805 RRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEEN 864
Query: 670 RLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRRE--QERL 727
RLR EA RL + E+ER+ +E Q ++E R+ Q+++E R+L +Q+++++ Q +L
Sbjct: 865 RLRMEEEAARLRHE-EEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 923
Query: 728 QAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
+ ++ Q Q L E +K EE++ ERQL+EEQ ++ +E
Sbjct: 924 PSSSTWGQQSNTTACQ-SQATLSLAEIQKLEEER---ERQLREEQRRQQRE 970
Score = 81.6 bits (200), Expect = 3e-15
Identities = 48/133 (36%), Positives = 85/133 (63%), Gaps = 11/133 (8%)
Query: 660 LQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER--REQERREQERREQERQLAE 717
L+K K + E+ R+ AE + E+ E++R+E+ RR+QE R Q+ E++RRE+E E
Sbjct: 729 LEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE----E 784
Query: 718 QERRREQERLQAERELQ-----EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ 772
RR+++E L+ +RE + +RE+ R Q+E+ R LEE++++EE++R E L++++
Sbjct: 785 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 844
Query: 773 EKKAKEAAGASKA 785
E+ AK A +A
Sbjct: 845 EEAAKWAREEEEA 857
Score = 65.9 bits (159), Expect = 2e-10
Identities = 112/531 (21%), Positives = 205/531 (38%), Gaps = 97/531 (18%)
Query: 287 PDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEE 346
PD + G +TD V S P + S S QE+ + R+ KT +
Sbjct: 348 PDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEA--SQFERKDEPKTEQT 405
Query: 347 PAASGRIICHSYLERLLNVEVPQKVGSEQ---------KEPPEEAEPVAAAEPEVPENNG 397
A + +E L +VP + G E + P + A P+ P VP
Sbjct: 406 EKAEEE----TRMENSLPAKVPSR-GDEMVADVQQPLSQIPSDTASPLLILPPPVP---- 456
Query: 398 NNSWPHNDTEIANSTPNPKPAASSPETP-----SAGQQEAKTDQADGPREPPQSARRKRS 452
NP P ETP G + D +G + Q A + +
Sbjct: 457 ----------------NPSPTLRPVETPVVGAPGMGSVSTEPDDEEGLKHLEQQAEKMVA 500
Query: 453 YKQAVSELDEEQHLEDEELQPPRSKTPSSPC------------PASKVVRPLRTFLHTVQ 500
Y Q S LD+E+ +LQ R+K S P P ++ P
Sbjct: 501 YLQD-SALDDERLAS--KLQEHRAKGVSIPLMHEAMQKWYYKDPQGEIQGPFN------- 550
Query: 501 RNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKR 560
NQ + A M +KR ++ Q L ++ +
Sbjct: 551 -NQEMAEWFQAGYFTMSLLVKRAC-------DESFQPLGDIMKMWGRVPFSPGPAPPPHM 602
Query: 561 RRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK 620
L++ +L R++ L + Q Q + ++ I+Q++AQ+ A++++ A +
Sbjct: 603 GELDQERLTRQQELTALYQM-----QHLQYQQFLIQQQYAQV-----LAQQQKAALSSQQ 652
Query: 621 KKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER---------- 670
++ A +++ + + + + + + + + + + Q
Sbjct: 653 QQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDL 712
Query: 671 -LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQA 729
L L + ++ E+ + + EQERRE E R + R E+ER+ E+ RR+++E L
Sbjct: 713 PLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAK-REEEERKRQEELRRQQEEIL-- 769
Query: 730 ERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA-ERQLQEEQEKKAKEA 779
R QE E+ R ++E +R+ EE +++ +Q +A RQ +EE+ ++ +EA
Sbjct: 770 -RRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEA 819
Score = 61.6 bits (148), Expect = 3e-09
Identities = 78/375 (20%), Positives = 163/375 (43%), Gaps = 70/375 (18%)
Query: 381 EAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPK-PAASSPETPSAGQQEAKTDQAD- 438
E +P A+ +P V E G + W D + +TP P E A + E + +A+
Sbjct: 693 ELQPTAS-QPTVWE--GGSVW---DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEM 746
Query: 439 -GPREPPQSARR---KRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRT 494
RE + R+ +R ++ + EE+ EE + R K + + LR
Sbjct: 747 RAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRR 806
Query: 495 FLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQK 554
+R Q + ++R R + E+ER++ E L RK+E E + +
Sbjct: 807 QREEEERQQQ------------EEALRRLEERRRE--EEERRKQEELLRKQEEEAAKWAR 852
Query: 555 VEEDKRRRLEEVKLK-----------REERLRKVLQARERVEQMKEEKKKQIEQKFAQID 603
EE+ +RRLEE +L+ EER RK L+ + + E M++ +++Q + Q
Sbjct: 853 EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 912
Query: 604 EKTEKAKEERL-----------------------AEEKAKKKAAAKKMEEVEARRKQEEE 640
++ ++ + +L AE + ++ +++ E + R+++E
Sbjct: 913 QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE-- 970
Query: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
++ LQQ+++++ Q+K + + K L E +++E R+ ++++Q++++
Sbjct: 971 --LMKALQQQQQQQ------QQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1022
Query: 701 QERREQERREQERQL 715
++ + R L
Sbjct: 1023 HQQPNRARNNTHSNL 1037
Score = 34.3 bits (77), Expect = 0.54
Identities = 21/93 (22%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
Query: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730
L +EAK A+Q ERR +++ Q+R++Q+ +Q++++ +Q +Q ++++
Sbjct: 1178 LGDTSEAKEFAKQF-LERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQPQQQDSVWGMNH 1236
Query: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRL 763
L + + +Q E + KK+++Q++
Sbjct: 1237 STLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKM 1269
Score = 32.3 bits (72), Expect = 2.1
Identities = 35/168 (20%), Positives = 73/168 (43%), Gaps = 14/168 (8%)
Query: 17 QKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQD 76
+K E L + + W E +EEA+R + E + ++ RK++ + VQ
Sbjct: 834 RKQEELLRKQEEEAAKWARE-EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELE-VQ- 890
Query: 77 ENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATM 136
R++ R+ + Q + RRL+ + ++LA + + S + + A + AT+
Sbjct: 891 ------RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 944
Query: 137 ALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAEQHVT 184
+LA E L + E Q +L+ ++ ++Q +Q ++
Sbjct: 945 SLAEIQKLEEERERQL--REEQRRQQRELMKALQ---QQQQQQQQKLS 987
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 118 bits (296), Expect = 2e-26
Identities = 83/251 (33%), Positives = 158/251 (62%), Gaps = 22/251 (8%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREER-LRKVLQARERVEQMKE 589
+++ER R + + +E+ E++RRQ +KR R +E +L+ +E+ LR+ + RE+ EQM+E
Sbjct: 259 RQEERLREQEGKMREQEEKMRRQ----EKRLREQEKELREQEKELREQKKLREQEEQMQE 314
Query: 590 EKKKQIEQKFAQIDEKTEK--AKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWL 647
+++K EQ+ ++ E+ EK +EERL E++ + + +KM + E R +++E L
Sbjct: 315 QEEKMWEQE-EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDER-----L 368
Query: 648 QQEEEERRHQELL--QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERRE 705
+++EE R QE + Q++K +E+ER+R E ++ + E+ REQE + Q++ E +
Sbjct: 369 REKEERMREQEKMWEQEEKMQEEERIR---EREKKMREEEETMREQEEKMQKQEENMWEQ 425
Query: 706 QERREQERQLAEQ-ERRREQERLQAERE-LQEREKALRLQKEQLQRELEEKKKKEEQQRL 763
+E+ Q+++L EQ E+ EQE++Q + E + E+E+ +R Q+E + E+K ++E+ R
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ--EKKMWRQEKMRE 483
Query: 764 AERQLQEEQEK 774
E Q+ E++EK
Sbjct: 484 QEDQMWEQEEK 494
Score = 117 bits (293), Expect = 5e-26
Identities = 84/280 (30%), Positives = 163/280 (58%), Gaps = 35/280 (12%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKV--EEDKRRRLEEVKLKREERL-RKVLQARERVEQM 587
+EKE + + LR +EE Q + +K+ +E+K R EE ++EERL + Q RE+ ++M
Sbjct: 295 QEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 354
Query: 588 KEEKKKQIEQKFAQIDEKTEKAKE--------ERLAEEKAKKKAAAKKMEEVEARRKQEE 639
++++++ EQ ++ EK E+ +E E++ EE+ ++ K EE E R+QEE
Sbjct: 355 RDQEERMWEQD-ERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEE 413
Query: 640 EARRLR---WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQER--- 693
+ ++ W Q+E+E ++ + QK+K EQE++++ E ++ EQ E+ R ++E
Sbjct: 414 KMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE--KIWEQEEKIRDQEEMWGQ 471
Query: 694 -----REQERREQE----RREQERREQERQLAEQERR--REQERLQAERELQEREKALRL 742
R+++ REQE +E++ R+QE+++ +QE R + ERL+ + E +K +
Sbjct: 472 EKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQ 531
Query: 743 QKEQLQREL----EEKKKKEEQQRLAERQLQEEQEKKAKE 778
Q+E+++ E +EKK ++++++ E + E+EKK +E
Sbjct: 532 QEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 571
Score = 117 bits (292), Expect = 6e-26
Identities = 74/249 (29%), Positives = 147/249 (59%), Gaps = 14/249 (5%)
Query: 531 KEKERQRLENLRRKEEA--EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK 588
+EK+ R E +R +E+ EQ + + +E K EE +++ERLR+ + ++M
Sbjct: 471 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMW 530
Query: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
++++K E+K Q EK +EE++ EE+ ++ K EE E R+QEE+ +Q
Sbjct: 531 QQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK------MQ 584
Query: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQER 708
++EE+ R QE +K E++E++++ E E++ E+ E+++ +++ +E++
Sbjct: 585 EQEEKMREQE---EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKM 641
Query: 709 REQERQLAEQERR-REQERLQAERE--LQEREKALRLQKEQLQRELEEKKKKEEQQRLAE 765
+EQE ++ EQE + REQE E+E +Q +E+ +R Q+E++Q + E+ +++EE+ R E
Sbjct: 642 QEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQE 701
Query: 766 RQLQEEQEK 774
++ ++EK
Sbjct: 702 EKMWGQEEK 710
Score = 116 bits (291), Expect = 8e-26
Identities = 95/300 (31%), Positives = 163/300 (54%), Gaps = 44/300 (14%)
Query: 513 RSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE 572
R + + RNT + K+K + E LR E + + V+E KR KL+R +
Sbjct: 168 RDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKR------KLERAK 221
Query: 573 RLRKVLQARERVEQM--KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEE 630
L +Q E+M +EE+ ++ E+K + +EK + +EERL E++ K + +KM
Sbjct: 222 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR-QEERLREQEGKMREQEEKMRR 280
Query: 631 VEAR--------RKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEA----- 677
E R R+QE+E R + L+++EE+ + QE +K E++E++R+ E
Sbjct: 281 QEKRLREQEKELREQEKELREQKKLREQEEQMQEQE---EKMWEQEEKMREQEEKMWRQE 337
Query: 678 KRLAEQREQER-REQERREQERR-----------EQERREQERR-EQERQLAEQERRREQ 724
+RL EQ +Q R +EQ+ R+QE R E+ REQE+ EQE ++ E+ER RE+
Sbjct: 338 ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRER 397
Query: 725 ERLQAERELQEREKALRLQK------EQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
E+ E E RE+ ++QK EQ ++E ++++ E++++L E++ +EQE+K E
Sbjct: 398 EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE 457
Score = 116 bits (290), Expect = 1e-25
Identities = 69/260 (26%), Positives = 154/260 (59%), Gaps = 12/260 (4%)
Query: 529 DPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR-KVLQARERVEQM 587
+ ++K R + E + ++E + + +++ E ++ +E K++ EER+R + + RE E M
Sbjct: 349 EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETM 408
Query: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEAR----- 642
+E+++K +Q+ +++ ++ +++RL E+K K K E+ E +QEE+ R
Sbjct: 409 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 468
Query: 643 ----RLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER 698
+ W Q++ E+ Q Q++K +QE+ + + +R+ EQ E+ R ++ER +++
Sbjct: 469 WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ-KMWDQEERMWEQDERLREKEERMREQK 527
Query: 699 REQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKE 758
+ ++ E+ R E++ Q E++ ++E+++ E ++EREK +R ++E++ RE EEK +++
Sbjct: 528 KMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMR-EEEEMMREQEEKMQEQ 586
Query: 759 EQQRLAERQLQEEQEKKAKE 778
E++ + + EQE+K +E
Sbjct: 587 EEKMREQEEKMWEQEEKMQE 606
Score = 115 bits (287), Expect = 2e-25
Identities = 75/259 (28%), Positives = 159/259 (61%), Gaps = 13/259 (5%)
Query: 527 RMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE--ERLRKVLQARERV 584
+M +EK R++ + + +EE + + QK+ + + R E+ + RE ER+R+ + ++
Sbjct: 474 KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQE 533
Query: 585 EQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 644
E+M+EEKK Q EQ+ D++ + +EER+ E + K + + M E E + +++EE R
Sbjct: 534 EKMREEKKTQ-EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592
Query: 645 R----WLQQEEEERRHQELL-QKKKEEEQERLRKAAEAKRLAEQREQERREQERR--EQE 697
+ W Q+E+ + + +++ Q++K EQE K E + + ++E++ +EQE + EQE
Sbjct: 593 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE 652
Query: 698 RREQERREQERREQERQLAEQERRREQ-ERLQAERE-LQEREKALRLQKEQLQRELEEKK 755
+ +E+ E+ R ++E+ ++E+ REQ E++Q + E ++E+E+ +R Q+E++ + EEK
Sbjct: 653 EKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQ-EEKM 711
Query: 756 KKEEQQRLAERQLQEEQEK 774
+E++ + +++E++E+
Sbjct: 712 WGQEEKMWGQEEMREKEER 730
Score = 113 bits (282), Expect = 9e-25
Identities = 74/263 (28%), Positives = 156/263 (59%), Gaps = 21/263 (7%)
Query: 529 DPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERV---E 585
+ +EK +++ EN+ +EE E ++Q++ E K + E+ K++ +E K+ + E++ E
Sbjct: 410 EQEEKMQKQEENMWEQEEKEW-QQQRLPEQKEKLWEQEKMQEQEE--KIWEQEEKIRDQE 466
Query: 586 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEAR-RKQEEEARRL 644
+M ++KK Q+ + E +EE++ +++ K ++M E + R R++EE R
Sbjct: 467 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ 526
Query: 645 RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQER--REQERREQE 702
+ + Q+EE+ R ++ Q+++++ ++ K E +R+ E RE++ RE+E REQE + QE
Sbjct: 527 KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRE-REKKMREEEEMMREQEEKMQE 585
Query: 703 RREQERREQERQLAEQERRREQERLQAERE-----------LQEREKALRLQKEQLQREL 751
+ E+ R ++E+ ++E+ +EQE E+E +QE+E+ + Q+E++Q +
Sbjct: 586 QEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQE 645
Query: 752 EEKKKKEEQQRLAERQLQEEQEK 774
E+ ++EE+ R E +++E++EK
Sbjct: 646 EKMWEQEEKMREQEEKMREQEEK 668
Score = 112 bits (281), Expect = 1e-24
Identities = 97/439 (22%), Positives = 210/439 (47%), Gaps = 45/439 (10%)
Query: 366 EVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETP 425
E +K+ ++K E+ + + E E+ E E + E
Sbjct: 273 EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
Query: 426 SAGQQEAKTDQADGPREPPQSAR--RKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPC 483
Q+E +Q RE Q R +R ++Q ++E+ + ++E + +
Sbjct: 333 MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEE 392
Query: 484 PASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRR 543
+ + +R T++ + M + + KE ++QRL +
Sbjct: 393 RIREREKKMREEEETMREQEEKMQK------------QEENMWEQEEKEWQQQRLPEQKE 440
Query: 544 K---EEAEQLRRQKV-EEDKRRRLEEVKLKREERLRKVLQARERVEQM--KEEKKKQIEQ 597
K +E Q + +K+ E++++ R +E +E+++ + + RE+ +QM +EEK + EQ
Sbjct: 441 KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ 500
Query: 598 KF-----------AQIDEKTEKAK--------EERLAEEKAKKKAAAKKMEEVEARRKQE 638
K ++ EK E+ + EE++ EEK ++ K ++ E R++E
Sbjct: 501 KMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEE 560
Query: 639 EEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER 698
R + +++EEE R QE +K +E++E++R+ E E++ QE+ E+ ++E+
Sbjct: 561 RMREREKKMREEEEMMREQE---EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617
Query: 699 REQERREQERREQERQLAEQERR---REQERLQAERELQEREKALRLQKEQLQRELEEKK 755
++ E + +EQE + EQE + +E++ + E +++E+E+ +R Q+E++Q + E+ +
Sbjct: 618 MWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 677
Query: 756 KKEEQQRLAERQLQEEQEK 774
++EE+ + E +++E++EK
Sbjct: 678 EQEEKMQGQEEKMREQEEK 696
Score = 112 bits (280), Expect = 2e-24
Identities = 99/469 (21%), Positives = 213/469 (45%), Gaps = 43/469 (9%)
Query: 318 LAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKE 377
L ++ + +QE +RR +RL ++ E L QK EQ+E
Sbjct: 264 LREQEGKMREQEEKMRRQEKRLREQEKE-------------LREQEKELREQKKLREQEE 310
Query: 378 PPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQA 437
+E E + E W + + E Q+E +Q
Sbjct: 311 QMQEQEEKMWEQEEKMREQEEKMWRQEER-----LWEQEKQMREQEQKMRDQEERMWEQD 365
Query: 438 DGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLH 497
+ RE + R + + ++ EE+ + + E + + +R
Sbjct: 366 ERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE------------ETMREQEE 413
Query: 498 TVQRNQMLMTPTSAPRSVMKSFIKRNTPL-----RMDPKEKERQRLENLRRKEEAEQLRR 552
+Q+ + M + ++ L + +EK ++ E +R +EE +
Sbjct: 414 KMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK 473
Query: 553 QKVEEDKRRRLEEVKLKREERLRKVLQAR-ERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 611
+ ++K R E+ ++EE++R Q ++ E+M E+ ++ E++ ++K +E
Sbjct: 474 KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQE 533
Query: 612 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERL 671
E++ EEK ++ K ++ E R++E R + +++EEE R QE +K +E++E++
Sbjct: 534 EKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE---EKMQEQEEKM 590
Query: 672 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR---REQERLQ 728
R+ E E++ QE+ E+ ++E+ ++ E + +EQE + EQE + +E++ +
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE 650
Query: 729 AERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777
E +++E+E+ +R Q+E++Q + EEK +++E++ + + EQE+K +
Sbjct: 651 QEEKMREQEEKMREQEEKMQGQ-EEKMREQEEKMQGQEEKMREQEEKMR 698
Score = 110 bits (275), Expect = 6e-24
Identities = 70/244 (28%), Positives = 142/244 (58%), Gaps = 27/244 (11%)
Query: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 591
E+ R++ E +R +++ Q + EE K + E+ +EE++R+ + RER ++M+EE+
Sbjct: 514 ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 573
Query: 592 KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE 651
+ EQ E+ + +EE++ E++ K +KM+E E + ++EE W Q+EE
Sbjct: 574 EMMREQ------EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK---MWEQEEE 624
Query: 652 EERRHQ-ELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERR----EQERREQERR-- 704
++ + Q E++ +++E+ QE+ K E + ++E++ REQE + E++ REQE +
Sbjct: 625 DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684
Query: 705 --EQERREQERQLAEQERRR---------EQERLQAERELQEREKALRLQKEQLQRELEE 753
E++ REQE ++ QE + ++E++ + E++E+E+ +R QKE++Q L E
Sbjct: 685 GQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPE 744
Query: 754 KKKK 757
+++
Sbjct: 745 HEER 748
Score = 105 bits (261), Expect = 3e-22
Identities = 77/261 (29%), Positives = 156/261 (59%), Gaps = 26/261 (9%)
Query: 530 PKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVL-QARERVEQMK 588
P+ + E + R+EE +LR Q E K R+ EE ++EERLR+ + RE+ E+M+
Sbjct: 225 PQVQTNTLQEEMWRQEE--ELREQ---EKKIRKQEEKMWRQEERLREQEGKMREQEEKMR 279
Query: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
++K+ EQ+ +++ E ++++L E++ + + +KM E E + +++EE W Q
Sbjct: 280 RQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKM---WRQ 336
Query: 649 QE---EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE--- 702
+E E+E++ +E QK +++E+ R + +RL E+ E+ R +++ EQE + QE
Sbjct: 337 EERLWEQEKQMREQEQKMRDQEE---RMWEQDERLREKEERMREQEKMWEQEEKMQEEER 393
Query: 703 --RREQERREQERQLAEQERR--REQERLQAERELQEREKALRLQKEQL--QRELEEKKK 756
RE++ RE+E + EQE + +++E + + E + +++ L QKE+L Q +++E+++
Sbjct: 394 IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 453
Query: 757 K--EEQQRLAERQLQEEQEKK 775
K E+++++ +++ QEKK
Sbjct: 454 KIWEQEEKIRDQEEMWGQEKK 474
Score = 93.2 bits (230), Expect = 1e-18
Identities = 78/261 (29%), Positives = 139/261 (53%), Gaps = 38/261 (14%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
KE++ LE R E+L+++ E ++ RL E + K E +L +KE
Sbjct: 166 KERDALSLELYRNTITNEELKKKNAELQEKLRLAESE-KSEIQLN-----------VKEL 213
Query: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 650
K+K KF +T +EE +E+ ++ K ++ E +QEE R +E
Sbjct: 214 KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMRE 273
Query: 651 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQER------- 703
+EE+ ++ +K+ E+++ LR+ + K L EQ++ REQE EQ + ++E+
Sbjct: 274 QEEKMRRQ--EKRLREQEKELRE--QEKELREQKKL--REQE--EQMQEQEEKMWEQEEK 325
Query: 704 -REQERR---------EQERQLAEQERR-REQERLQAERELQEREKALRLQKEQLQRELE 752
REQE + EQE+Q+ EQE++ R+QE E++ + REK R+++++ E E
Sbjct: 326 MREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQE 385
Query: 753 EKKKKEEQQRLAERQLQEEQE 773
EK ++EE+ R E++++EE+E
Sbjct: 386 EKMQEEERIREREKKMREEEE 406
Score = 89.4 bits (220), Expect = 1e-17
Identities = 72/286 (25%), Positives = 143/286 (50%), Gaps = 36/286 (12%)
Query: 529 DPKEKERQRLENLRRKEEAEQ-----LRRQKVE--------EDKRRRLEEVKLKREERLR 575
D K+ Q E LRR+ EA+ L QK E +D R+ E+ L + L
Sbjct: 71 DEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLA 130
Query: 576 -----------KVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAA 624
++ +A V ++ + IE+ + D + + + E+ KKK A
Sbjct: 131 GRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNA 190
Query: 625 A--KKMEEVEARRKQ--------EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKA 674
+K+ E+ + + + + R ++L + + QE + +++EE +E+ +K
Sbjct: 191 ELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKI 250
Query: 675 AEAKRLAEQREQERREQERREQERREQERREQER-REQERQLAEQERR-REQERLQAERE 732
+ + ++E+ REQE + +E+ E+ RR+++R REQE++L EQE+ REQ++L+ + E
Sbjct: 251 RKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEE 310
Query: 733 LQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
+ ++ ++E+ RE EEK ++E++ + + EQE+K ++
Sbjct: 311 QMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 356
Score = 72.4 bits (176), Expect = 2e-12
Identities = 48/193 (24%), Positives = 101/193 (52%), Gaps = 10/193 (5%)
Query: 520 IKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQ 579
++ + + +EK +++ E +R +EE + +K++E + + E+ + E+ +Q
Sbjct: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
Query: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
+E + +EEK ++ E+K + +EK + +EE++ E++ K + +KM E E + + +E
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKM-REQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687
Query: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 699
E R ++EE+ R QE +K QE E K ++ +E+ E+ R ++E+
Sbjct: 688 EKMR-----EQEEKMRGQE----EKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKM 738
Query: 700 EQERREQERREQE 712
++ E E R E
Sbjct: 739 QERLPEHEERCSE 751
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 115 bits (288), Expect = 2e-25
Identities = 71/247 (28%), Positives = 148/247 (59%), Gaps = 17/247 (6%)
Query: 527 RMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQ 586
+M +E++ Q+ E + E+ EQ+R+Q EE + E+V+ + E+ ++ Q R++ EQ
Sbjct: 207 QMGEQEEQMQKQEE-QMGEQEEQMRKQ--EEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQ 263
Query: 587 MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRW 646
M+E++++ EQ+ + +K + +EE+ E++ + + E+ E R+QEE+ R
Sbjct: 264 MREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMR------EQEEQMREQEEQMR---- 313
Query: 647 LQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQ 706
+QEE+ R +E + K++E+ E+ + E K ++E++ EQE + Q++ EQ R+++
Sbjct: 314 -EQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQE 372
Query: 707 ERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAER 766
EQ R+ EQ R++E++ + E ++ E+++ + QKEQ++ + E+ +++EQ R E
Sbjct: 373 ---EQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
Query: 767 QLQEEQE 773
+ E++E
Sbjct: 430 HMGEQKE 436
Score = 111 bits (278), Expect = 3e-24
Identities = 75/264 (28%), Positives = 158/264 (59%), Gaps = 26/264 (9%)
Query: 531 KEKERQ-RLENLRRKEEAEQLRRQKV---EEDKRRRLEEVKLKREERLRKVLQARERVEQ 586
+E+E Q R + + +E+ Q+R Q+ E++ + R +E ++ +E Q E+ EQ
Sbjct: 153 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEG-----QMGEQEEQ 207
Query: 587 M--KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 644
M +EE+ ++ E++ + +E+ K +E+ +E+ +K + ++ E RKQEE+ R
Sbjct: 208 MGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMR-- 265
Query: 645 RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ------ERREQERREQER 698
+QEE+ R +E + K+KE+ ++ + + +++ EQ EQ + REQE + +E+
Sbjct: 266 ---EQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQ 322
Query: 699 REQERREQERR-EQERQLAEQER---RREQERLQAERELQEREKALRLQKEQLQRELEEK 754
EQ +++E+ EQ+ Q+ EQ+ ++E++ + E ++Q++E+ +R Q+EQ++++ E+
Sbjct: 323 EEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQM 382
Query: 755 KKKEEQQRLAERQLQEEQEKKAKE 778
+K+EEQ R E Q+ E++E+ ++
Sbjct: 383 RKQEEQMRKQEEQMGEQKEQMGEQ 406
Score = 107 bits (268), Expect = 4e-23
Identities = 88/284 (30%), Positives = 162/284 (57%), Gaps = 45/284 (15%)
Query: 531 KEKERQ-RLENLRRKEEAEQLRRQKV---EEDKRRRLEEVKLKREERLRKVLQARERVEQ 586
+E+E Q R + + +E+ Q+R Q+ E++ + R +E +++ +E Q RE+ Q
Sbjct: 132 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG-----QVREQEGQ 186
Query: 587 MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRW 646
++E++ + EQ+ Q+ E+ E+ E+ E+ +K + E+ E RKQEE+
Sbjct: 187 VREQEGQMGEQE-GQMGEQEEQMGEQ----EEQMQKQEEQMGEQEEQMRKQEEQMG---- 237
Query: 647 LQQEEEERRHQELLQKKKEE---EQERLRKAAEAKRLAEQ---REQERREQERREQERRE 700
+QEE+ ++ +E +QK++E+ ++E++R+ E R E+ +++E+ EQE + E+ E
Sbjct: 238 -EQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEE 296
Query: 701 QERREQER-REQERQLAEQERR-REQERLQAERELQ----------------EREKALRL 742
Q R ++E+ REQE Q+ EQE + REQE ++E Q ++E+ +
Sbjct: 297 QMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGE 356
Query: 743 QKEQLQRELEEKKKKEEQQRLAERQL--QEEQEKKAKEAAGASK 784
Q+EQ+Q++ E+ +K+EEQ R E Q+ QEEQ +K +E G K
Sbjct: 357 QEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQK 400
Score = 102 bits (254), Expect = 2e-21
Identities = 69/257 (26%), Positives = 154/257 (59%), Gaps = 26/257 (10%)
Query: 531 KEKERQ-RLENLRRKEEAEQLRRQKV---EEDKRRRLEEVKLKREERLRKVLQARERVEQ 586
+E+E Q R + + +E+ Q+R Q+ E++ + R +E +++ +E Q RE+ Q
Sbjct: 90 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG-----QVREQEGQ 144
Query: 587 MKEEKKKQIEQKFAQIDEKTEKAKEE--RLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 644
++E++ Q+ ++ Q+ E+ + +E+ ++ E++ + + ++ E E + ++E
Sbjct: 145 VREQEG-QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMG- 202
Query: 645 RWLQQEEEERRHQELLQKKKE---EEQERLRKAAEAKRLAEQREQERREQERREQERREQ 701
+QEE+ +E +QK++E E++E++RK E ++ EQ EQ ++++E+ +++ +
Sbjct: 203 ---EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEE--QMGEQEEQVQKQEEQVQKQEEQM 257
Query: 702 ERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 761
++E++ REQE Q+ EQE + +++ Q E+E Q E Q+EQ++ + E+ +++EEQ
Sbjct: 258 RKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGE-----QEEQMREQEEQMREQEEQM 312
Query: 762 RLAERQLQEEQEKKAKE 778
R E Q++E++E+ K+
Sbjct: 313 REQEEQMREQEEQMGKQ 329
Score = 95.9 bits (237), Expect = 2e-19
Identities = 71/264 (26%), Positives = 151/264 (57%), Gaps = 26/264 (9%)
Query: 531 KEKERQ-RLENLRRKEEAEQLRRQKV---EEDKRRRLEEVKLKREERLRKVLQARERVEQ 586
+E+E Q R + + +E+ Q+R Q+ E++ + R +E +++ +E Q RE+ Q
Sbjct: 97 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG-----QVREQEGQ 151
Query: 587 MKEEKKKQIEQKFAQIDEKTEKAKEE--RLAEEKAKKKAAAKKMEEVEARRKQEEE--AR 642
++E++ Q+ ++ Q+ E+ + +E+ ++ E++ + + +M E E + ++EE
Sbjct: 152 VREQEG-QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGE 210
Query: 643 RLRWLQQEEEERRHQELLQKKKEE---EQERLRKAAEAKRLAEQREQERREQERREQERR 699
+ +Q++EE+ QE +K+EE EQE + E + ++ + ++E++ REQE +
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQ 270
Query: 700 EQERREQ-----ERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 754
+E+ EQ E+ EQE Q EQE + ++ E +++E+E+ +R Q+EQ++ + E+
Sbjct: 271 MREQEEQMLKQKEQTEQEEQTGEQEEQMREQ----EEQMREQEEQMREQEEQMREQEEQM 326
Query: 755 KKKEEQQRLAERQLQEEQEKKAKE 778
K+EEQ + Q+ E++E+ K+
Sbjct: 327 GKQEEQMWEQKEQMWEQKEQMWKQ 350
Score = 95.5 bits (236), Expect = 2e-19
Identities = 76/272 (27%), Positives = 157/272 (57%), Gaps = 24/272 (8%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRR-RLEEVKLKREERLRKVL-QARERVEQMK 588
KEK + E L+ E + + ++E KR+ +++ L +E ++R+ Q RE+ Q++
Sbjct: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR 69
Query: 589 E------EKKKQIEQKFAQIDEKTEKAKEE--RLAEEKAKKKAAAKKMEEVEAR-RKQEE 639
E E++ Q+ ++ Q+ E+ + +E+ ++ E++ + + ++ E E + R+QE
Sbjct: 70 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 129
Query: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER--REQE--RRE 695
+ R +E+E + ++ Q +++E Q R ++ ++ + REQE REQE RE
Sbjct: 130 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 189
Query: 696 QERR--EQE----RREQERREQERQLAEQERR---REQERLQAERELQEREKALRLQKEQ 746
QE + EQE +E++ EQE Q+ +QE + +E++ + E ++ E+E+ ++ Q+EQ
Sbjct: 190 QEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQ 249
Query: 747 LQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
+Q++ E+ +K+EEQ R E Q++E++E+ K+
Sbjct: 250 VQKQEEQMRKQEEQMREQEEQMREQEEQMLKQ 281
Score = 89.7 bits (221), Expect = 1e-17
Identities = 68/258 (26%), Positives = 153/258 (59%), Gaps = 21/258 (8%)
Query: 531 KEKERQ-RLENLRRKEEAEQLRRQKV---EEDKRRRLEEVKLKREERLRKVLQARERVEQ 586
+E+E Q R + + +E+ Q+R Q+ E++ + R +E +++ +E Q RE+ Q
Sbjct: 69 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG-----QVREQEGQ 123
Query: 587 MKEEKKKQIEQKFAQIDEKTEKAKEE--RLAEEKAKKKAAAKKMEEVEAR-RKQEEEARR 643
++E++ Q+ ++ Q+ E+ + +E+ ++ E++ + + ++ E E + R+QE + R
Sbjct: 124 VREQEG-QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 182
Query: 644 LRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQE-RREQERREQERR--E 700
+E+E + ++ Q ++EEQ + +++ +Q EQ +E++ R+QE + E
Sbjct: 183 QEGQVREQEGQMGEQEGQMGEQEEQ----MGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE 238
Query: 701 QERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQ 760
QE + Q++ EQ ++ EQ R++E++ + E +++E+E+ + QKEQ ++E E+ ++EEQ
Sbjct: 239 QEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQE-EQTGEQEEQ 297
Query: 761 QRLAERQLQEEQEKKAKE 778
R E Q++E++E+ ++
Sbjct: 298 MREQEEQMREQEEQMREQ 315
Score = 89.4 bits (220), Expect = 1e-17
Identities = 74/255 (29%), Positives = 140/255 (54%), Gaps = 18/255 (7%)
Query: 539 ENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQK 598
E L+ K Q Q VE +K E++L +E RK+ +++ ++ Q+ ++
Sbjct: 7 EELKEKNAELQEELQLVETEK----SEIQLHIKELKRKL-----ETDKIPLPQEGQVREQ 57
Query: 599 FAQIDEKTEKAKEE--RLAEEKAKKKAAAKKMEEVEAR-RKQEEEARRLRWLQQEEEERR 655
Q+ E+ + +E+ ++ E++ + + ++ E E + R+QE + R +E+E +
Sbjct: 58 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 117
Query: 656 HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER-REQERREQER--REQE 712
++ Q +++E Q R ++ ++ + REQE + +E+ Q R +E + REQE REQE
Sbjct: 118 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 177
Query: 713 RQLAEQERR-REQERLQAERELQ--EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 769
Q+ EQE + REQE E+E Q E+E+ + Q+EQ+Q++ E+ ++EEQ R E Q+
Sbjct: 178 GQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMG 237
Query: 770 EEQEKKAKEAAGASK 784
E++E+ K+ K
Sbjct: 238 EQEEQVQKQEEQVQK 252
Score = 88.2 bits (217), Expect = 3e-17
Identities = 69/259 (26%), Positives = 153/259 (59%), Gaps = 23/259 (8%)
Query: 530 PKEKERQRLENLRRKEEAEQLRRQKV---EEDKRRRLEEVKLKREERLRKVLQARERVEQ 586
P+E + + E R++E Q+R Q+ E++ + R +E +++ +E Q RE+ Q
Sbjct: 49 PQEGQVREQEGQVREQEG-QVREQEGQVREQEGQVREQEGQVREQEG-----QVREQEGQ 102
Query: 587 MKEEKKKQIEQKFAQIDEKTEKAKEE--RLAEEKAKKKAAAKKMEEVEAR-RKQEEEARR 643
++E++ Q+ ++ Q+ E+ + +E+ ++ E++ + + ++ E E + R+QE + R
Sbjct: 103 VREQEG-QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 161
Query: 644 LRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR--EQERREQERREQ 701
+E+E + ++ Q +++E Q R ++ ++ + EQE + EQE + Q++ EQ
Sbjct: 162 QEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQ 221
Query: 702 --ERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE 759
E+ EQ R+ QE Q+ EQE + +++ E ++Q++E+ +R Q+EQ+ RE EE+ +++E
Sbjct: 222 MGEQEEQMRK-QEEQMGEQEEQVQKQ----EEQVQKQEEQMRKQEEQM-REQEEQMREQE 275
Query: 760 QQRLAERQLQEEQEKKAKE 778
+Q L +++ E++E+ ++
Sbjct: 276 EQMLKQKEQTEQEEQTGEQ 294
Score = 87.0 bits (214), Expect = 7e-17
Identities = 58/195 (29%), Positives = 115/195 (58%), Gaps = 18/195 (9%)
Query: 521 KRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR-KVLQ 579
K+ +R ++ Q + L++KE+ EQ + +E++ R EE ++EE++R + Q
Sbjct: 259 KQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ 318
Query: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
RE+ EQM +++++ EQK ++K + K+E E+ +++ +K E E RKQEE
Sbjct: 319 MREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE---EQMGEQEEQMQKQE--EQVRKQEE 373
Query: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 699
+ R+ QEE+ R+ +E ++K++E+ E + +++ EQ+EQ REQE + E++
Sbjct: 374 QMRK-----QEEQMRKQEEQMRKQEEQMGE------QKEQMGEQKEQ-MREQEEQMGEQK 421
Query: 700 EQERREQERREQERQ 714
EQ R+++E ++++
Sbjct: 422 EQMRKQEEHMGEQKE 436
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 115 bits (287), Expect = 2e-25
Identities = 96/370 (25%), Positives = 179/370 (48%), Gaps = 21/370 (5%)
Query: 429 QQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLE-----DEELQPPRSKTPSSPC 483
Q E +TD+ R R++ +++ + ++E+ + D + + R++
Sbjct: 70 QTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERER 129
Query: 484 PASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRR 543
+ R QR + R ++ R KE+ER++ RR
Sbjct: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189
Query: 544 KEEAEQLRRQKVEEDKRRRLEEVKLKRE-----ERLRKVLQARERVEQMKEEKKKQIEQK 598
+ E ++ + K E+ R E + +RE ER R+ + R+R + + E++KQ E++
Sbjct: 190 ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERE 249
Query: 599 FAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQE 658
A + +TE+ KE ++ + + +K E + RK++ R R +++ E +R +E
Sbjct: 250 RAS-ERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERE 308
Query: 659 LLQ---KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQL 715
+ +K+E E+ER R+ + RE+ER E++R+ Q ++ER Q RE RQ
Sbjct: 309 RERERNRKRERERERERERERQRETERDREKER-ERKRKRQTEMDRERNRQTGREGRRQ- 366
Query: 716 AEQERRREQER-LQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 774
AE+ER RE+ER Q+ RE +ERE+ R + Q +RE + +K ++ Q+ E + Q E+EK
Sbjct: 367 AERERERERERDRQSAREREERERD-RDRDRQKERERQTEKDRDGQR---ETEKQREREK 422
Query: 775 KAKEAAGASK 784
+ G +
Sbjct: 423 DRESERGRER 432
Score = 105 bits (263), Expect = 1e-22
Identities = 61/256 (23%), Positives = 140/256 (54%), Gaps = 2/256 (0%)
Query: 521 KRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQA 580
KR T D K +ER+R ++ RK + + R++ E+++ R+ + + ++ E+ R +
Sbjct: 68 KRQTERETDRK-RERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKE 126
Query: 581 RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE 640
RER + + E+ + + + E+ A++ER + +++ ++ + E R++ +
Sbjct: 127 RERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQ 186
Query: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
RR R Q+E+E + ++ +E E+ER + ++ RE++R+ + RE+E++
Sbjct: 187 ERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQA 246
Query: 701 QERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKE-E 759
+ R ER + + E+ER R+++R + ++E + + R ++ + RE E K++++ E
Sbjct: 247 ERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRE 306
Query: 760 QQRLAERQLQEEQEKK 775
++R ER + E+E++
Sbjct: 307 RERERERNRKRERERE 322
Score = 101 bits (252), Expect = 3e-21
Identities = 62/253 (24%), Positives = 135/253 (53%), Gaps = 8/253 (3%)
Query: 529 DPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE---ERLRKVLQARERVE 585
D ++ER R + R+ E Q R+ + +RRR ++ KR+ ER R + RER
Sbjct: 50 DGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQT 109
Query: 586 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 645
+ +++++ E+ + E+ + + ER + + + ++ + E R+++ + R R
Sbjct: 110 DRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQR 169
Query: 646 WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERRE 705
++ ++ R +E K ++E +ER R+ + + ++ + RE+ER + E ER+
Sbjct: 170 QTERNRQKERERE---KNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR 226
Query: 706 QERREQERQ-LAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 764
Q RE++RQ E+ER ++ ER +A ER+K ++++ R+ + ++K+ E+Q
Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERERERDR-DRDRDRRQKERERQTDR 285
Query: 765 ERQLQEEQEKKAK 777
+RQ + E++++ +
Sbjct: 286 KRQRRTERDRETE 298
Score = 101 bits (251), Expect = 4e-21
Identities = 78/299 (26%), Positives = 155/299 (51%), Gaps = 44/299 (14%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRR----LEEVKLKREERLRKVLQARERVEQ 586
KE+ER+R E + + E ++ R ++ E+D+ R+ E + + +ER R+ + R+R +
Sbjct: 60 KERERRR-EKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQRE 118
Query: 587 MKEEKKKQIEQKFAQ-----IDEKTEKAKE---ERLAEEKAKKKAAAKKMEEVEARRKQE 638
+ ++K+ E++ + D +T+ +E +R AE++ +++ ++ + E R++E
Sbjct: 119 KERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKE 178
Query: 639 EE------ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE 692
E RR R Q+E+E + ++ +E E+ER + ++ RE++R+ +
Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT 238
Query: 693 RREQERREQERREQER---REQERQLAEQERRREQERLQAERELQEREKALRL------- 742
RE+E++ + R ER R++ER+ E++R R+++R Q ERE Q K R
Sbjct: 239 EREREKQAERERASERETERDKERE-RERDRDRDRDRRQKERERQTDRKRQRRTERDRET 297
Query: 743 -QKEQLQRELE-------------EKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALN 787
+K + QRE E E++++ E+QR ER ++E+E+K K + N
Sbjct: 298 ERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERN 356
Score = 100 bits (250), Expect = 5e-21
Identities = 73/258 (28%), Positives = 139/258 (53%), Gaps = 13/258 (5%)
Query: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 591
E+ R+R + E E+ R+ E D++R+ E + K+ ER R + ER ++ + E+
Sbjct: 207 ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER 266
Query: 592 KKQIE------QKFAQIDEKTEKAKE-ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 644
+ + ++ Q D K ++ E +R E K +++ ++ E +R++E E R
Sbjct: 267 DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERE 326
Query: 645 RWLQQEEEERRHQELLQKKK---EEEQERLRKAAEAKRLAEQREQERREQERREQERREQ 701
R Q+E E R +E +K+K E ++ER R+ R +RE+ER E+ER Q RE+
Sbjct: 327 RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERER-ERERDRQSARER 385
Query: 702 ERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 761
E RE++R +++RQ E+ER+ E++R ++RE+ + E+ + E++K++ ++
Sbjct: 386 EERERDR-DRDRQ-KERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRE 443
Query: 762 RLAERQLQEEQEKKAKEA 779
R ERQ + ++ K +
Sbjct: 444 RDRERQTDRQAGRQRKRS 461
Score = 100 bits (249), Expect = 6e-21
Identities = 67/260 (25%), Positives = 139/260 (53%), Gaps = 16/260 (6%)
Query: 527 RMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE-ERLRKVLQARERVE 585
R +E+ R++ + R + + RR+K KR R E + RE ER R+ + R+R
Sbjct: 58 RQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQR 117
Query: 586 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 645
+ + ++K+ E++ + E+ + + E + ++ A ++ + + R+++ E R +
Sbjct: 118 EKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQK 177
Query: 646 WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR---EQERREQERREQE 702
+ E E+ QE +++++ E+E + ++R +RE+ER E ER+ Q RE++
Sbjct: 178 ---EREREKNRQERRERERQREKENKTEDRHSER-GRERERERETETETERKRQTDRERD 233
Query: 703 RREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKE---- 758
R+ + RE+E+Q AE+ER E+E + + +ER++ + Q +RE + +K++
Sbjct: 234 RQRKTEREREKQ-AERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292
Query: 759 ---EQQRLAERQLQEEQEKK 775
E +R ERQ + E+E++
Sbjct: 293 RDRETERKRERQRERERERE 312
Score = 95.1 bits (235), Expect = 3e-19
Identities = 59/236 (25%), Positives = 128/236 (54%), Gaps = 6/236 (2%)
Query: 527 RMDPKEKERQRLENLRRKEEAEQLR--RQKVEEDKRRRLEEVKLKREERLRKVLQAR-ER 583
R +E++RQR R+++AE+ R ++ E DK R E + + +R +K + + +R
Sbjct: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDR 285
Query: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 643
Q + E+ ++ E+K + E+ + + R E + +++ ++ E E R++E E +R
Sbjct: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKR 345
Query: 644 LRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQER-REQERREQE 702
R + + E R Q + +++ E+ER R+ ++ A +RE+ R+++R R++ER Q
Sbjct: 346 KRQTEMDRERNR-QTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQT 404
Query: 703 RREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKE-QLQRELEEKKKK 757
++++ + + + E+E+ RE ER + +E++K +E Q R+ ++K+
Sbjct: 405 EKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 90.1 bits (222), Expect = 8e-18
Identities = 80/339 (23%), Positives = 157/339 (46%), Gaps = 39/339 (11%)
Query: 429 QQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKV 488
++E +TD RE + R R K+ E + ++ E E + +KT +
Sbjct: 158 ERERQTD-----RERQRQTERNRQ-KEREREKNRQERRERERQREKENKTEDRHSERGRE 211
Query: 489 VRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAE 548
R +R + R + K+ R +E ER + R + +
Sbjct: 212 RERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRD 271
Query: 549 QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEK 608
+ RRQK ++ R+ + + +R ER R+ + RER + + E+++ + +
Sbjct: 272 RDRRQK---ERERQTDRKRQRRTERDRETERKRERQRERERERER----------NRKRE 318
Query: 609 AKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ 668
+ ER E + +++ + +E E +RK++ E R R Q E RR E +++E E+
Sbjct: 319 RERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAE---RERERER 375
Query: 669 ERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQ 728
ER R++A RE+E RE++R ++E+ER+ ++ R+ +R+ E++R RE++R
Sbjct: 376 ERDRQSA--------REREERERDRDRDRQKERERQTEKDRDGQRE-TEKQREREKDR-- 424
Query: 729 AERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQ 767
E E+ +E+ +++ E+ ++ + R A RQ
Sbjct: 425 ------ESERGRERGREREKQKGRERDRERQTDRQAGRQ 457
Score = 77.0 bits (188), Expect = 7e-14
Identities = 52/203 (25%), Positives = 112/203 (55%), Gaps = 11/203 (5%)
Query: 580 ARERVEQMKEEKKKQIEQ--KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ 637
+R R + +++ + Q K A D++ ++ER E+ ++K ++ + + R++
Sbjct: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKER---ERRREKRQTERETDRKRERRR 83
Query: 638 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER---REQERR 694
E++ R R +E + R +E +++ + E++R R+ ++ +RE ER R ++R+
Sbjct: 84 EKDRHRKRDRHRERQRDREKER-ERQTDRERDRQREKERNRQKERERETEREGERGRDRQ 142
Query: 695 EQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 754
+RE+ER+ +E+ERQ ++ER+R+ ER + + +E+ + R ++E+ QRE E K
Sbjct: 143 TDGQRERERQRDAEKERERQ-TDRERQRQTERNRQKEREREKNRQERRERER-QREKENK 200
Query: 755 KKKEEQQRLAERQLQEEQEKKAK 777
+ +R ER+ + E E + +
Sbjct: 201 TEDRHSERGRERERERETETETE 223
Score = 75.1 bits (183), Expect = 3e-13
Identities = 62/298 (20%), Positives = 137/298 (45%), Gaps = 14/298 (4%)
Query: 429 QQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLE-------DEELQPPRSKTPSS 481
+Q + Q + RE + RR+R ++ E++H E + E + + +
Sbjct: 169 RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQT 228
Query: 482 PCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENL 541
+ + R +R + T + + +R+ D ++KER+R +
Sbjct: 229 DRERDRQRKTEREREKQAERERASERETERDKERER---ERDRDRDRDRRQKERERQTDR 285
Query: 542 RRKEEAEQLRR--QKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKF 599
+R+ E+ R +K E + R E + ++ ER R+ + RER + + +++K+ E+K
Sbjct: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKR 345
Query: 600 AQIDEKTEKAKEE--RLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQ 657
+ E + + R +A+++ ++ + ++ R++EE R +Q+E ER+ +
Sbjct: 346 KRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTE 405
Query: 658 ELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQL 715
+ ++E E++R R+ +R +ER +Q+ RE++R Q R+ R+ + L
Sbjct: 406 KDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
Score = 72.4 bits (176), Expect = 2e-12
Identities = 52/154 (33%), Positives = 80/154 (51%), Gaps = 15/154 (9%)
Query: 634 RRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQER 693
R +Q+E RR Q E E R +E + E++R RK + RE+ER Q
Sbjct: 56 RNRQKERERRREKRQTERETDRKRE-----RRREKDRHRKRDRHRERQRDREKERERQTD 110
Query: 694 REQER-REQERREQERREQERQLAEQERRREQERLQAERELQ---EREKALRLQKEQLQR 749
RE++R RE+ER Q+ RE+E + + R Q Q ERE Q E+E+ + +E+ QR
Sbjct: 111 RERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRER-QR 169
Query: 750 ELEEKKKKEEQ-----QRLAERQLQEEQEKKAKE 778
+ E ++KE + Q ER+ Q E+E K ++
Sbjct: 170 QTERNRQKEREREKNRQERRERERQREKENKTED 203
Score = 70.1 bits (170), Expect = 9e-12
Identities = 39/163 (23%), Positives = 91/163 (55%), Gaps = 7/163 (4%)
Query: 617 EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAE 676
E+ ++K ++ E+ + R+ + + R R + + RH+E + +++E + + + +
Sbjct: 55 ERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
Query: 677 AKRLAEQREQERREQERREQERREQERREQERREQERQL-AEQERRREQERLQAERELQE 735
+R E+ Q+ RE+E + R ++R+ +RE+ERQ AE+ER R Q +RE Q
Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER-----QTDRERQR 169
Query: 736 REKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
+ + R ++ + ++ +E++++ E+QR E + ++ ++ +E
Sbjct: 170 QTERNRQKEREREKNRQERRER-ERQREKENKTEDRHSERGRE 211
Score = 69.7 bits (169), Expect = 1e-11
Identities = 44/139 (31%), Positives = 82/139 (58%), Gaps = 3/139 (2%)
Query: 643 RLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER-REQERREQERREQ 701
R R Q+E E RR + +++ + ++ER R+ ++ RE++R RE+ER Q RE+
Sbjct: 54 RERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRER 113
Query: 702 ER-REQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQ 760
+R RE+ER Q+ + E ER E+ R + +ERE+ +KE+ ++ E++++ E+
Sbjct: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173
Query: 761 QRLAERQLQE-EQEKKAKE 778
R ER+ ++ QE++ +E
Sbjct: 174 NRQKEREREKNRQERRERE 192
Score = 58.9 bits (141), Expect = 2e-08
Identities = 35/122 (28%), Positives = 67/122 (54%), Gaps = 7/122 (5%)
Query: 666 EEQERLRKAAEAKRLAEQREQERREQERREQER------REQERREQERREQERQLAEQE 719
+E R R +A + A+ ++ER Q+ RE+ R RE +R+ + RRE++R
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
Query: 720 RRREQERLQAERELQ-EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
R Q + ERE Q +RE+ + +KE+ +++ E++ + E +R +RQ ++E++ +
Sbjct: 94 HRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153
Query: 779 AA 780
A
Sbjct: 154 DA 155
Score = 38.5 bits (88), Expect = 0.029
Identities = 57/285 (20%), Positives = 102/285 (35%), Gaps = 18/285 (6%)
Query: 360 ERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAA 419
ER E K E E E E E D E +
Sbjct: 190 ERERQREKENKTEDRHSERGRERERERETETETERKR------QTDRERDRQRKTERERE 243
Query: 420 SSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEE-QHLEDEELQPPRSKT 478
E A ++E + D+ + RE + R R K+ + D + Q + + + R +
Sbjct: 244 KQAERERASERETERDK-ERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE 302
Query: 479 PSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRL 538
+ R +R + T R + KR MD +ER R
Sbjct: 303 RQRERERERERNRKRERERERERERERQRETERDREKERER-KRKRQTEMD---RERNRQ 358
Query: 539 ENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQK 598
+ +AE+ R ++ E D++ E REER R + R++ E+ ++ +K + Q+
Sbjct: 359 TGREGRRQAERERERERERDRQSARE-----REERERDRDRDRQK-ERERQTEKDRDGQR 412
Query: 599 FAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 643
+ + EK +E E+ +++ K E R+ + R+
Sbjct: 413 ETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQ 457
Score = 36.2 bits (82), Expect = 0.14
Identities = 39/174 (22%), Positives = 77/174 (44%), Gaps = 19/174 (10%)
Query: 527 RMDPKEKERQR---LENLRRKEEAEQLR---RQK-----VEEDKRRRLEEVKLKREERLR 575
R +E+ER+R ++ R +EE E+ R RQK E+D+ + E K + E+ R
Sbjct: 365 RQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDR 424
Query: 576 KVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARR 635
+ + RER + +++K ++ +++ Q D + + ++ + A + + + R
Sbjct: 425 ESERGRERGREREKQKGRERDRE-RQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNR 483
Query: 636 KQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAK---RLAEQREQ 686
R +RW E+ + + + R R A + RL E+R Q
Sbjct: 484 ----PTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQ 533
Score = 35.8 bits (81), Expect = 0.19
Identities = 21/99 (21%), Positives = 50/99 (50%), Gaps = 13/99 (13%)
Query: 698 RREQERREQERR------------EQERQLAEQERRREQERLQAERELQEREKALRLQKE 745
RR +E RR + + ++ER R +E+ Q ERE +R++ R +K+
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERE-TDRKRERRREKD 86
Query: 746 QLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 784
+ ++ ++++ ++++ ERQ E++++ ++ K
Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQK 125
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 114 bits (284), Expect = 5e-25
Identities = 139/550 (25%), Positives = 232/550 (42%), Gaps = 121/550 (22%)
Query: 242 DPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILPDNFS------TPTG 295
DP G+G GR+ + L S A P P R +P+ P + + P G
Sbjct: 329 DP-GRGPTWGRAGASLARGPQPDRTHPSAAVPVCP-RSASASPLTPCSVTRSVHRCAPAG 386
Query: 296 SRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIIC 355
R + R P A SP+P + S V K+E + ++ +E +A R
Sbjct: 387 ERGE----RRKPNAGGSPAPVRRRPEASPVQKKEKKDKE------RENEKEKSALAR--- 433
Query: 356 HSYLERLLNVEVPQKVGSEQK---EPPEEAEPVAAAEPEVPENNGNNSW---------PH 403
ER L + E P + A P P + SW P
Sbjct: 434 ----ERSLKKRQSLPASPRARLSASTASELSPKSKARPSSP----STSWHRPASPCPSPG 485
Query: 404 NDTEIANSTPNPKPAASSPETPSAGQQEAK-TDQADGPREPPQSARRKRSYKQAVSELDE 462
+ P+P+ +SP+ ++EAK + A GP + QS RR + K++ +
Sbjct: 486 PGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPAS- 544
Query: 463 EQHLEDEELQPPRSKTPS-SPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIK 521
P S PS +P P K P T PT A +V+ S
Sbjct: 545 ----------PAPSPAPSPTPAPPQKEQPPAET-------------PTDA--AVLTS--- 576
Query: 522 RNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQAR 581
P P + + +EEA +L +K RR QAR
Sbjct: 577 ---PPAPAPPVTPSKPMAGTTDREEATRLLAEK------RR----------------QAR 611
Query: 582 ERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEA 641
E+ E+ ++E++ Q E +++R+ EE+ ++A A+ E EARR++E+EA
Sbjct: 612 EQREREEQERRLQAE-------------RDKRMREEQLAREAEARAEREAEARRREEQEA 658
Query: 642 RRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQ 701
R +QEE+ER LQK+KEE + R R+ AE +RL ++ +++EQER+E+ +R +
Sbjct: 659 REKAQAEQEEQER-----LQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLE 713
Query: 702 ERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKK---KE 758
E ++ R+ +++E +++++ + A E KA+ + LQ+E +K++ +E
Sbjct: 714 EIMKRTRKS---EVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEPIPQE 770
Query: 759 EQQRLAERQL 768
Q L ++L
Sbjct: 771 PQWSLPSKEL 780
Score = 88.2 bits (217), Expect = 3e-17
Identities = 92/393 (23%), Positives = 157/393 (39%), Gaps = 40/393 (10%)
Query: 410 NSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDE 469
N+ +P P PE ++E K + + +E AR + K+ L
Sbjct: 395 NAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSAS 454
Query: 470 ---ELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPL 526
EL P PSSP T P+ P + P
Sbjct: 455 TASELSPKSKARPSSPS--------------TSWHRPASPCPSPGPGHTLP-------PK 493
Query: 527 RMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQ 586
P+ +RRKEEA++ EDK + ++E A
Sbjct: 494 PPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKES----AAPASPAPSP 549
Query: 587 MKEEKKKQIEQKFAQIDEKTEKA---KEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 643
+++ + T+ A A K A + EA R E+ R+
Sbjct: 550 APSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQ 609
Query: 644 LR-WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE 702
R ++EE+ERR Q K+ EEQ L + AEA+ E + R EQE RE+ + EQE
Sbjct: 610 AREQREREEQERRLQAERDKRMREEQ--LAREAEARAEREAEARRREEQEAREKAQAEQE 667
Query: 703 RREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQR 762
+E+ ++++E A E++RL+ E+ Q++E+ ++++ ++ LEE K+ +
Sbjct: 668 EQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQ----ERQERRKRLEEIMKRTRKSE 723
Query: 763 LAERQLQEEQEKKAKEAAGASKALNVTVDVQSP 795
++E +++Q+ K A G+S V+ +SP
Sbjct: 724 VSE--TKQKQDSKEANANGSSPEPVKAVEARSP 754
Score = 60.5 bits (145), Expect = 7e-09
Identities = 58/215 (26%), Positives = 92/215 (42%), Gaps = 26/215 (12%)
Query: 408 IANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLE 467
+A + P P+P+ +P A D P + P + + S KQ E +
Sbjct: 18 VARTPPEPRPSPEGDPSPPPPPMSALVP--DTPPDTPPAMKNATSSKQLPLEPESPSGQV 75
Query: 468 DEELQPPRSKTPSS------PCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRS---VMKS 518
PP+ ++PSS P P + R R R +PT+ P S K
Sbjct: 76 GPRPAPPQEESPSSEAKSRGPTPPAMGPRDARP-----PRRSSQPSPTAVPASDSPPTKQ 130
Query: 519 FIKRNTPLRMDPKEKERQRLENLR-------RKEEAEQLRRQKVEEDKRRRLEEVKLKRE 571
+K+ KE+ +R + L KEE + R+K +++RRRLEE +LK E
Sbjct: 131 EVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAE 190
Query: 572 ERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKT 606
+R R L+ R+R Q E+ K++ E + +KT
Sbjct: 191 QR-RAALEERQR--QKLEKNKERYEAAIQRSVKKT 222
Score = 47.0 bits (110), Expect = 8e-05
Identities = 31/94 (32%), Positives = 56/94 (59%), Gaps = 8/94 (8%)
Query: 704 REQERREQERQLAEQERRREQERLQAERE---LQEREKALRLQKEQLQ---RELEEKKKK 757
+++ ++ ER +ERR E+ + A ++ L++ EKA L+++QLQ R LEE++ K
Sbjct: 129 KQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLK 188
Query: 758 EEQQR--LAERQLQEEQEKKAKEAAGASKALNVT 789
EQ+R L ERQ Q+ ++ K + A +++ T
Sbjct: 189 AEQRRAALEERQRQKLEKNKERYEAAIQRSVKKT 222
Score = 47.0 bits (110), Expect = 8e-05
Identities = 29/94 (30%), Positives = 57/94 (60%), Gaps = 5/94 (5%)
Query: 668 QERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERL 727
++ ++KA E +LA++R +ER + ++ E+ E+ + +E+QL E+ RR E++RL
Sbjct: 129 KQEVKKAGERHKLAKERREERAKY-LAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRL 187
Query: 728 QAERE---LQEREK-ALRLQKEQLQRELEEKKKK 757
+AE+ L+ER++ L KE+ + ++ KK
Sbjct: 188 KAEQRRAALEERQRQKLEKNKERYEAAIQRSVKK 221
Score = 43.1 bits (100), Expect = 0.001
Identities = 51/228 (22%), Positives = 92/228 (40%), Gaps = 34/228 (14%)
Query: 368 PQKVGSEQKEPPEEAEPVAAAEPEVPENNG---NNSWPHNDTEIANSTPN----PKPAAS 420
P+ S + +P P++A P+ P + N+ + +P+ P+PA
Sbjct: 23 PEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPAPP 82
Query: 421 SPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPS 480
E+PS+ EAK+ P P+ AR R QP + P+
Sbjct: 83 QEESPSS---EAKSRGPTPPAMGPRDARPPR-----------------RSSQPSPTAVPA 122
Query: 481 SPCPASKVVRPLRTFLHTV--QRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRL 538
S P +K H + +R + +A ++V ++ LR ++ R+RL
Sbjct: 123 SDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRL 182
Query: 539 ENLRRKEEA-----EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQAR 581
E R K E E+ +RQK+E++K R ++ ++ ++ Q R
Sbjct: 183 EEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAEIRQQR 230
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/127 (26%), Positives = 62/127 (48%), Gaps = 25/127 (19%)
Query: 596 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 655
+Q+ + E+ + AKE R EE+AK AA K + WL++EE+ +
Sbjct: 129 KQEVKKAGERHKLAKERR--EERAKYLAAKKAV-----------------WLEKEEKAKA 169
Query: 656 HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQL 715
+E ++ QER R+ E + AEQR E++R++ E+ ++ +R ++
Sbjct: 170 LRE------KQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTW 223
Query: 716 AEQERRR 722
AE ++R
Sbjct: 224 AEIRQQR 230
Score = 40.0 bits (92), Expect = 0.010
Identities = 28/122 (22%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Query: 610 KEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE-EQ 668
++ R ++ A + +++ ++A L +E E R + L KK E+
Sbjct: 104 RDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEK 163
Query: 669 ERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQ 728
E KA K+L E+R + ++ + EQ R E R++++ E+ ++ E +R ++
Sbjct: 164 EEKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTW 223
Query: 729 AE 730
AE
Sbjct: 224 AE 225
Score = 39.7 bits (91), Expect = 0.013
Identities = 32/115 (27%), Positives = 60/115 (52%), Gaps = 13/115 (11%)
Query: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 707
+QE ++ + L K++ EE+ + A +A L E+E + + RE++ +E+ RR +E
Sbjct: 129 KQEVKKAGERHKLAKERREERAKYLAAKKAVWL----EKEEKAKALREKQLQERRRRLEE 184
Query: 708 RREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQR 762
+R L ++RR E ER+ Q+ EK + +QR +++ + QQR
Sbjct: 185 QR-----LKAEQRRAALE----ERQRQKLEKNKERYEAAIQRSVKKTWAEIRQQR 230
Score = 38.9 bits (89), Expect = 0.022
Identities = 28/104 (26%), Positives = 53/104 (50%), Gaps = 3/104 (2%)
Query: 593 KQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE 652
KQ +K + + ++ +EER AKK +K E+ +A R+++ + RR R EE+
Sbjct: 129 KQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRR---LEEQ 185
Query: 653 ERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQ 696
+ ++ +E ++++L K E A QR ++ E R+Q
Sbjct: 186 RLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAEIRQQ 229
Score = 35.4 bits (80), Expect = 0.24
Identities = 96/452 (21%), Positives = 143/452 (31%), Gaps = 99/452 (21%)
Query: 66 RKKRRISYVQDENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVT 125
R++ S VQ + + R K +S+ R L+ + S+ +
Sbjct: 404 RRRPEASPVQKKEKKDKER--ENEKEKSALARERSLKKRQSLP---------------AS 446
Query: 126 RAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAEQHVTQ 185
A +A+ L+ S P SP+ +P
Sbjct: 447 PRARLSASTASELSPKSKARPSSPSTSWHRP----------------------------- 477
Query: 186 LMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATPQDPKG 245
P P SP P P P+ + K + R E S A P+D
Sbjct: 478 ---ASPCP---SPGPGHTLPPKP---PSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQ 528
Query: 246 QGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILPDNFSTPTGSRT-DSQSVR 304
A +P P SP P P +E+ A TPT + S
Sbjct: 529 SKRRASNEKESAAPASPAPSPAPSPT-PAPPQKEQPPA-------ETPTDAAVLTSPPAP 580
Query: 305 HSPIAPSSP---------SPQVLAQKYSLVAKQ---ESVVRRASRRLAKKTAEEP---AA 349
P+ PS P + ++LA+K +Q E RR K+ EE A
Sbjct: 581 APPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREA 640
Query: 350 SGRIICHSYLERLLNVEVPQKVGSEQKE------PPEEAEPVAAAEPEVPENNGNNSWPH 403
R + R E +K +EQ+E EEAE + E E +
Sbjct: 641 EARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQ 700
Query: 404 NDTEIANSTPN----PKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRS---YKQA 456
+ E K S + + +Q++K A+G P A RS K+A
Sbjct: 701 QEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEA 760
Query: 457 VSELDEEQHLEDEELQPPRSKTPSSPCPASKV 488
V + E+ Q P+ PS PAS V
Sbjct: 761 VQK-------EEPIPQEPQWSLPSKELPASLV 785
Score = 33.1 bits (74), Expect = 1.2
Identities = 28/114 (24%), Positives = 52/114 (45%), Gaps = 10/114 (8%)
Query: 38 QEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSR--RKSRSSQ 95
QEE ER+ ++ +E E + +++ R ++ + Q++ R R+RL +++R S+
Sbjct: 666 QEEQERL--QKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSE 723
Query: 96 LSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATMALAAPSSPTPESP 149
+S + + +DS E A NGS V A + P P+ P
Sbjct: 724 VSETK-QKQDSKEANA-----NGSSPEPVKAVEARSPGLQKEAVQKEEPIPQEP 771
Score = 31.6 bits (70), Expect = 3.5
Identities = 42/162 (25%), Positives = 58/162 (35%), Gaps = 34/162 (20%)
Query: 189 TEPLPRTLSPT--PASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATPQDPKGQ 246
T P PR SP P+ P S +P + ++ P A + + + P+ P GQ
Sbjct: 21 TPPEPRP-SPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLE-----PESPSGQ 74
Query: 247 GVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILPDNFSTPTGSRTDSQSVRHS 306
GPR +P +SP E P P D++ R S
Sbjct: 75 -----------------VGPRPAPPQEESPSSEAKSRGPTP-----PAMGPRDARPPRRS 112
Query: 307 PIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPA 348
S PSP + S KQE +LAK+ EE A
Sbjct: 113 ----SQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERA 150
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 112 bits (280), Expect = 2e-24
Identities = 82/266 (30%), Positives = 146/266 (54%), Gaps = 36/266 (13%)
Query: 517 KSFIKRNTPLRM-------DPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLK 569
++ +K NT L+M P + + E R+ E E + K E + R+ E +
Sbjct: 8 RAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKE----R 63
Query: 570 REERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKME 629
RE RK RER ++ K E+ K+ ++K E+ KEER E K +++ K
Sbjct: 64 REREKRK----REREKERKRERGKK--------EKKGERKKEER--ERKKRRREKENKEG 109
Query: 630 EVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR 689
E + +RK++E+ R R ++ +E R +E +K+EE +ER RK E+RE+ER
Sbjct: 110 EEKEKRKKKEKKERGRTSKEGKERERKEE---RKREERKERERKK-------EEREKERE 159
Query: 690 EQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQR 749
+ER+++ER++ +E+ER+E+ER+ ++ R +ER + ERE +ER + + +K++ +R
Sbjct: 160 RKERKKRERKQVGEKEEERKEKERKERKKRERNRKER-KKERERKERRERKKERKKKEER 218
Query: 750 ELEEKKKKEEQQRLAERQLQEEQEKK 775
+ E +K ++ R ER +E +E+K
Sbjct: 219 KKERQKDRQTNWREKERGKRERKERK 244
Score = 111 bits (277), Expect = 4e-24
Identities = 71/228 (31%), Positives = 136/228 (59%), Gaps = 23/228 (10%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
+E+ER+ K+E E R+++ E ++R+ E K ++ ER +K E+ E
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKK--------EKKGER 90
Query: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 650
KK++ E+K K + KE + EEK K+K K E+ E R +E R R +++
Sbjct: 91 KKEERERK------KRRREKENKEGEEKEKRK----KKEKKERGRTSKEGKERERKEERK 140
Query: 651 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERRE--QER 708
EER+ +E ++++E+E+ER + ++ ++E+ER+E+ER+E+++RE+ R+E +ER
Sbjct: 141 REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKER 200
Query: 709 REQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKK 756
+ER+ ++ER++++ER ++E Q+ + +KE+ +RE +E+KK
Sbjct: 201 ERKERRERKKERKKKEER---KKERQKDRQTNWREKERGKRERKERKK 245
Score = 110 bits (276), Expect = 5e-24
Identities = 70/206 (33%), Positives = 127/206 (61%), Gaps = 12/206 (5%)
Query: 578 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ 637
++ RER + ++E KK+ E + + + EK K ER EK +K+ KK E + RK+
Sbjct: 38 IREREREIETRKEGKKERESERKKERREREKRKRER---EKERKRERGKK--EKKGERKK 92
Query: 638 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 697
EE R+ R ++E +E +E +KK+++E+ R K + + E+R++E R++ R++E
Sbjct: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
Query: 698 RREQERREQERREQER-QLAEQERRREQ----ERLQAERELQEREKALRLQKEQLQRELE 752
RE+ER +ER+++ER Q+ E+E R++ ER + ER +ER+K R +KE+ +R+ E
Sbjct: 153 EREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKE-RERKERRERKKE 211
Query: 753 EKKKKE-EQQRLAERQLQEEQEKKAK 777
KKK+E +++R +RQ ++++ K
Sbjct: 212 RKKKEERKKERQKDRQTNWREKERGK 237
Score = 108 bits (271), Expect = 2e-23
Identities = 70/207 (33%), Positives = 132/207 (63%), Gaps = 22/207 (10%)
Query: 572 ERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEV 631
ER R++ +E ++ + E+KK+ ++ EK K ER EK +K+ KK E
Sbjct: 40 EREREIETRKEGKKERESERKKERRER--------EKRKRER---EKERKRERGKK--EK 86
Query: 632 EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 691
+ RK+EE R+ R ++E+E + +E ++KK+E++ER R + E K +R++ER+ +
Sbjct: 87 KGERKKEERERKKR--RREKENKEGEEKEKRKKKEKKERGRTSKEGKE--RERKEERKRE 142
Query: 692 ERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQREL 751
ER+E+ER+++E RE+ER +ER+ E+++ E+E + E+E +ER+K R +KE+
Sbjct: 143 ERKERERKKEE-REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER----K 197
Query: 752 EEKKKKEEQQRLAERQLQEEQEKKAKE 778
+E+++KE ++R ER+ +EE++K+ ++
Sbjct: 198 KERERKERRERKKERKKKEERKKERQK 224
Score = 84.7 bits (208), Expect = 4e-16
Identities = 45/160 (28%), Positives = 101/160 (63%), Gaps = 12/160 (7%)
Query: 630 EVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER- 688
E+ R ++ E + + ++ E ++ +E ++K+E E+ER R+ + ++ E++++ER
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
Query: 689 REQERREQERREQERREQERREQERQLA----------EQERRREQERLQAERELQEREK 738
R++ RRE+E +E E +E+ +++++++ +E R+ +ER + ER+ +EREK
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
Query: 739 ALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
R +KE+ +RE ++ +KEE+++ ER+ ++++E+ KE
Sbjct: 157 E-RERKERKKRERKQVGEKEEERKEKERKERKKRERNRKE 195
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 111 bits (278), Expect = 3e-24
Identities = 99/371 (26%), Positives = 182/371 (49%), Gaps = 64/371 (17%)
Query: 464 QHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRN 523
Q + E+++ + S A +V++P +++Q+ +T + +K+ K +
Sbjct: 512 QSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVT------AYLKNSRKEH 565
Query: 524 TPL--RMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR---KVL 578
+ R E+ ++RLE+L + E E+L +++ E K R+ EE +L++E + R ++L
Sbjct: 566 QRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERIL 625
Query: 579 QARERV------EQMKEEKKKQIEQK-FAQID--------------------EKTEKAKE 611
Q E++ E++++ KK ++ K F ID EK +K +
Sbjct: 626 QEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQ 685
Query: 612 ERLA--EEKAKKKAAAKKMEEVEARRKQEEEARRLR---WLQQEEEERRHQELLQKKKEE 666
ERL E+K AK++EE+ + EE R W QQEEE +L ++K E
Sbjct: 686 ERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALE 745
Query: 667 EQERLRKAAEAKRL----------------AEQREQERREQERREQERREQERREQERRE 710
+ R+ + E + L +Q E+ E+ E R+++R+E+ R
Sbjct: 746 HKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRIT 805
Query: 711 QERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ- 769
R+ E+E+RR +E++ ERE ERE+A R ++E+ RE +E+ KK E+ +RQ +
Sbjct: 806 YYREKEEEEQRRAEEQMLKERE--ERERAERAKREEELREYQERVKKLEEVERKKRQREL 863
Query: 770 --EEQEKKAKE 778
EE+E++ +E
Sbjct: 864 EIEERERRREE 874
Score = 81.3 bits (199), Expect = 4e-15
Identities = 72/289 (24%), Positives = 138/289 (47%), Gaps = 51/289 (17%)
Query: 525 PLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER- 583
PL E++R + +L ++E E++ ++E +K L+ + R+ ++L+ R+
Sbjct: 708 PLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKA-------LEHKNRMSRMLEDRDLF 760
Query: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 643
V ++K ++ E+K Q +E+ + + RL E K ++K ++ R K+EEE RR
Sbjct: 761 VMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRK---EERRITYYREKEEEEQRR 817
Query: 644 LR-WLQQEEEERRHQELLQKKKE--EEQERLRKAAEAKRLAEQREQERREQERREQERR- 699
+ +E EER E ++++E E QER++K E +R QRE E E+ERR +E R
Sbjct: 818 AEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERR 877
Query: 700 ----------------------------EQERR----EQERREQERQLAEQERRREQERL 727
+ E R E+E R E + ++ RR++ER
Sbjct: 878 LGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERP 937
Query: 728 QAERELQEREKALRLQKEQLQR----ELEEKKKKEEQQRLAERQLQEEQ 772
+ + ++RE +LR +++ R + ++ E+ R + R +++
Sbjct: 938 RRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDR 986
Score = 46.6 bits (109), Expect = 1e-04
Identities = 38/187 (20%), Positives = 79/187 (42%), Gaps = 21/187 (11%)
Query: 607 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE 666
EKA+EE + + + ++ + R K+ + + R ++ ER +E+
Sbjct: 1182 EKAREESWGPPRESRPSEEREWD----REKERDRDNQDREENDKDPERERDRERDVDRED 1237
Query: 667 EQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE--QERQLAEQERRREQ 724
R R +R + R+ RR+ R+ RRE++ R +ER+ +R R
Sbjct: 1238 RFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRG 1297
Query: 725 ERLQAERE---------------LQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 769
L++ERE ++ER+ R+ L R+ E + +E + + +
Sbjct: 1298 PPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWR 1357
Query: 770 EEQEKKA 776
E+++++
Sbjct: 1358 AEKDRES 1364
Score = 45.1 bits (105), Expect = 3e-04
Identities = 37/135 (27%), Positives = 70/135 (51%), Gaps = 23/135 (17%)
Query: 659 LLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQ 718
+LQ+K+E+ Q + + R QR RR+ +ER E ++E+ E E
Sbjct: 542 ILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELE------ 595
Query: 719 ERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK---EEQQRLAERQLQE--EQE 773
Q E ELQ+ KA ++E+L++E +E++K+ +E +++ ++ ++E EQ
Sbjct: 596 ---------QREAELQKVRKA---EEERLRQEAKEREKERILQEHEQIKKKTVRERLEQI 643
Query: 774 KKAKEAAGASKALNV 788
KK + A A K +++
Sbjct: 644 KKTELGAKAFKDIDI 658
Score = 41.6 bits (96), Expect = 0.003
Identities = 44/198 (22%), Positives = 89/198 (44%), Gaps = 12/198 (6%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
+EKE+ R E+ E+ ++ + +K R + REE + + R+R E
Sbjct: 1179 REKEKAREESWGPPRESRPSEEREWDREKER--DRDNQDREENDKDPERERDR------E 1230
Query: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKME-EVEARRKQEEEARRLRWLQQ 649
+ E +F + + E AEE + + ++++ + + + RR++ ++ R LR +
Sbjct: 1231 RDVDREDRFRR--PRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRD 1288
Query: 650 EEEERRHQELLQKKKEEEQERLRKAAEAK-RLAEQREQERREQERREQERREQERREQER 708
++R + + + EE R+A + K E+R+ RR RE++R +
Sbjct: 1289 LRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDRERE 1348
Query: 709 REQERQLAEQERRREQER 726
E+E+ E+ RE R
Sbjct: 1349 GEKEKASWRAEKDRESLR 1366
Score = 37.4 bits (85), Expect = 0.064
Identities = 48/198 (24%), Positives = 85/198 (42%), Gaps = 29/198 (14%)
Query: 571 EERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEE 630
EER + R+R Q +EE K E+ + D + + +E+R + +E
Sbjct: 1199 EEREWDREKERDRDNQDREENDKDPER---ERDRERDVDREDRFRRPR----------DE 1245
Query: 631 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQE--- 687
RR EE+ R + RR ++ E +R R E + L + R++
Sbjct: 1246 GGWRRGPAEESSSWR-----DSSRRDDRDRDDRRRERDDR-RDLRERRDLRDDRDRRGPP 1299
Query: 688 -RREQERREQERREQERREQ--ERREQERQLAEQERRREQER-LQAERELQEREKALRLQ 743
R E+E RR +R++ E R+ R++ R++ER ERE ++ + + R +
Sbjct: 1300 LRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAE 1359
Query: 744 KEQLQRELEEKKKKEEQQ 761
K+ RE + K E +
Sbjct: 1360 KD---RESLRRTKNETDE 1374
Score = 37.0 bits (84), Expect = 0.084
Identities = 24/139 (17%), Positives = 60/139 (43%), Gaps = 11/139 (7%)
Query: 636 KQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE 695
+++E+AR W E + ++KE +++ + RE+ ++ ER
Sbjct: 1179 REKEKAREESWGPPRESRPSEEREWDREKERDRDN-----------QDREENDKDPERER 1227
Query: 696 QERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKK 755
R+ +R ++ RR ++ + E + +R++ R ++ +R+L E++
Sbjct: 1228 DRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERR 1287
Query: 756 KKEEQQRLAERQLQEEQEK 774
+ + L+ E+E+
Sbjct: 1288 DLRDDRDRRGPPLRSEREE 1306
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 110 bits (274), Expect = 8e-24
Identities = 113/385 (29%), Positives = 192/385 (49%), Gaps = 49/385 (12%)
Query: 409 ANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLED 468
A + K SSP+T ++G + D A G Y + + + LE
Sbjct: 42 AGANRKKKINGSSPDTATSGGYHSPGDSATG------------IYGEGRASSTTLEDLES 89
Query: 469 EELQPPRSKTPSSPCPASKVVRPLRTFLHTV--QRNQMLMTPTSAPRSVMKSFIKRNTPL 526
+ Q SS S++ + + + T ++ + RS+ K + PL
Sbjct: 90 Q-YQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPL 148
Query: 527 RMDP-----KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQA- 580
+P K ++ Q N RKE R+ + E + + L + ++EERLR+ +
Sbjct: 149 APEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERL 208
Query: 581 RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE 640
RE+ E+++E++++ EQ E+ + +EERL E++ + +++ E E R ++EE
Sbjct: 209 REQEERLREQEERLCEQ------EERLREQEERLREQEERLCEQEERLREHEERLCEQEE 262
Query: 641 ARRLRWLQQEEEERRHQELLQKKKE---EEQERLRKAAEAKRLAEQREQERREQERR--- 694
R +QEE R +E L +++E E++ERLR+ E RL EQ E+ REQE R
Sbjct: 263 ----RLCEQEERLREQEERLHEQEERLCEQEERLREQEE--RLCEQ-EERLREQEERLCE 315
Query: 695 -EQERREQERR--EQERRE-QERQLAEQERRREQERLQAERE-LQEREKALRLQKEQLQR 749
E+ REQE R EQE+ QER L E E+ EQER Q E+E L ERE+ L E+++
Sbjct: 316 QEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLL----EEVEE 371
Query: 750 ELEEKKKKEEQQRLAERQLQEEQEK 774
LE+++ +++ +RL +++ +E E+
Sbjct: 372 LLEQERLRQQDERLWQQETLQELER 396
Score = 103 bits (257), Expect = 7e-22
Identities = 101/362 (27%), Positives = 176/362 (48%), Gaps = 36/362 (9%)
Query: 466 LEDEELQPPRSKTPSSPCPASKV---VRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKR 522
L+++ +P + P+ P ++ LR L +V R + M S + R
Sbjct: 140 LKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQ----AEVENNQMLSLLNR 195
Query: 523 NTPLRM-DPKEKERQRLENLRRKEE--AEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQ 579
R+ + +E+ R++ E LR +EE EQ R + +E++ R EE ++EERLR
Sbjct: 196 RQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLR---- 251
Query: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKA--KEERLAEEKAKKKAAAKKMEEVEARRKQ 637
E E++ E++++ EQ+ ++ E+ E+ +EERL E++ + + +++ E E R ++
Sbjct: 252 --EHEERLCEQEERLCEQE-ERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLRE 308
Query: 638 EEEARRLRWLQQEEEERRHQE-LLQKKKEEEQERLRKAAEAKRLAEQREQERRE------ 690
+EE R +QEE R +E L +++K QERL + E K L ++R QE +E
Sbjct: 309 QEE----RLCEQEERLREQEERLCEQEKLPGQERLLEEVE-KLLEQERRQEEQERLLERE 363
Query: 691 ---QERREQERREQERREQERREQERQLAEQERRREQERL--QAERELQEREKALRLQKE 745
+E E +E+ R++ ER Q+ L E ER RE ER+ L E+ R E
Sbjct: 364 RLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQRAEPRSGFE 423
Query: 746 QLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQ 805
+L E + + E+Q + ++ E+ + ++ AA A V + C TPQ
Sbjct: 424 ELNNENKSTLQLEQQVKELKKSGGAEEPRGSESAAAARPVAGAPVPQGAWMCGQAGWTPQ 483
Query: 806 GH 807
H
Sbjct: 484 EH 485
Score = 87.8 bits (216), Expect = 4e-17
Identities = 83/259 (32%), Positives = 135/259 (52%), Gaps = 38/259 (14%)
Query: 557 EDKRRRLEEVKLKREERLRKVLQARERVEQM----KEEKKKQIE--QKFAQIDEKTEKAK 610
ED + +E+ + + + Q E + + KEEKK +I QK + K +
Sbjct: 85 EDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQT 144
Query: 611 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE---- 666
E LA E + +++++ ++E E+ R LQ E E + LL +++EE
Sbjct: 145 AEPLAPEPPAGPSKVEQLQDETNHLRKELESVG-RQLQAEVENNQMLSLLNRRQEERLRE 203
Query: 667 EQERLRKAAEA-----KRLAEQREQERREQER-REQERR--EQERR---------EQERR 709
++ERLR+ E +RL EQ E+ R ++ER REQE R EQE R EQE R
Sbjct: 204 QEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEER 263
Query: 710 --EQERQLAEQERR--REQERL-QAERELQEREKALRLQKEQLQRELE-----EKKKKEE 759
EQE +L EQE R ++ERL + E L+E+E+ L Q+E+L+ + E E++ +E+
Sbjct: 264 LCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQ 323
Query: 760 QQRLAERQLQEEQEKKAKE 778
++RL E++ QE+ +E
Sbjct: 324 EERLCEQEKLPGQERLLEE 342
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 110 bits (274), Expect = 8e-24
Identities = 79/294 (26%), Positives = 165/294 (56%), Gaps = 20/294 (6%)
Query: 533 KERQRLENLRRKEEAEQLRRQKV--EEDKRRRLEEVKLKREERLR----KVLQARERVEQ 586
K R++ E + R+EE + +K+ +EDK R EE ++EE++R K+ + E++ +
Sbjct: 319 KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE 378
Query: 587 MKEEKKKQIEQKFAQ---IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 643
E+ ++Q E+ + Q I E+ EK +E+ +EK ++ K E+ E +QEE+ R
Sbjct: 379 QDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRE 438
Query: 644 LRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQER 703
L + Q++EE+ + +++K +EE+E++++ E + E++ QE+ E+ R+++ +QE
Sbjct: 439 LEEMMQDQEEKLRE--VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE 496
Query: 704 R--EQER---REQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKE 758
+ EQE R++E+ ++E+ +EQE +E + RE+ +RL +++ + + +E + +E
Sbjct: 497 KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556
Query: 759 EQQRLAERQLQEEQEKKAKEAAGASKALNVT----VDVQSPACTSYQMTPQGHR 808
++RL + + E A +G+ + +T V+++S S Q +R
Sbjct: 557 LEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610
Score = 107 bits (268), Expect = 4e-23
Identities = 91/319 (28%), Positives = 174/319 (54%), Gaps = 33/319 (10%)
Query: 484 PASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRR 543
P + ++ F H V+ + T R + RNT + KEK + E LR
Sbjct: 171 PENSLLEETLHFDHAVRMGTYIEKLTKE-RDAPSLELYRNTITDEELKEKNAELQEKLRL 229
Query: 544 KEEAEQLRRQKVEEDKRRRLEEVKL--------KREERLRKVLQARERVEQMKEEK---- 591
E +E+ Q +D +R+LE +L +RL K LQ+ Q + E+
Sbjct: 230 VE-SEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELW 288
Query: 592 ---KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL---R 645
+Q E+K + +EK ++ +EE++ E++ K + +KM E + ++EE R +
Sbjct: 289 NLLNQQQEEKMWRQEEKIQE-QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
Query: 646 WLQQEEEERRHQELLQKKKEE---EQERLRKAAEAKRLAEQREQERREQER-REQERREQ 701
+QEE+ R +E +++++E+ ++E++R+ E ++ EQ E+ R++E+ REQE + Q
Sbjct: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDE--KIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 702 E---RREQERREQERQLAEQER---RREQERLQAERELQEREKALRLQKEQLQRELEEKK 755
E R+E++ REQ+ ++ EQE R+E++ + E +Q++E+ LR +E++Q E E+ +
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 756 KKEEQQRLAERQLQEEQEK 774
++EE+ + E ++QE++EK
Sbjct: 466 EQEEKIQRQEEKIQEQEEK 484
Score = 107 bits (266), Expect = 7e-23
Identities = 66/256 (25%), Positives = 157/256 (61%), Gaps = 15/256 (5%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKV---EEDKRRRLEEVKLKREERLRKVLQARERVEQM 587
+++E+ + L+ +E+ E++ RQ+ E++++ R +E K+ R+E K+ + E++ +
Sbjct: 308 EQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEE--KIREQEEKIREQ 365
Query: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEV-EARRKQEEEARRLRW 646
+E+ +Q E+K + DEK ++ +EE +E+ ++ K+ E++ +K E+ ++R
Sbjct: 366 EEKMWRQ-EEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR- 423
Query: 647 LQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQ 706
+QEEE R +E +++ +E Q++ K E + ++ E++ +EQE + Q + E+ + ++
Sbjct: 424 -EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQE 482
Query: 707 ERREQERQLAEQERR---REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRL 763
E+ ++ +L +QE + +E++ + E ++ E+E+ ++ Q+E++QR+ E+K +E++ RL
Sbjct: 483 EKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ--EEKMREQEVRL 540
Query: 764 -AERQLQEEQEKKAKE 778
+ + +EQE + +E
Sbjct: 541 WQQEEKMQEQEVRLQE 556
Score = 105 bits (263), Expect = 1e-22
Identities = 70/265 (26%), Positives = 153/265 (57%), Gaps = 17/265 (6%)
Query: 526 LRMDPKEKERQRLENLRRKEE--AEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER 583
L +EK ++ E ++ +EE EQ + + +E+K R EE ++EE++R+ +E
Sbjct: 291 LNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE----QED 346
Query: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 643
+EEK ++ E+K + +EK + +EE++ E+ K + ++M E + +++EE R+
Sbjct: 347 KMWRQEEKIREQEEKIREQEEKMWR-QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 644 LRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE--Q 701
+ +QE++ R E +++++EE + K E + + + +E++ RE E + QE E Q
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 702 ERREQERREQERQLAEQERRREQERL--------QAERELQEREKALRLQKEQLQRELEE 753
E+ E+ +R++E+ ++E+ QE+L + E ++ +E+ + Q+E++Q + E+
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEK 525
Query: 754 KKKKEEQQRLAERQLQEEQEKKAKE 778
+++EE+ R E +L +++EK ++
Sbjct: 526 MQRQEEKMREQEVRLWQQEEKMQEQ 550
Score = 103 bits (256), Expect = 1e-21
Identities = 70/252 (27%), Positives = 151/252 (59%), Gaps = 12/252 (4%)
Query: 534 ERQRLENLRRKEEAEQLRRQ--KVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 591
E L NL +++ E++ RQ K++E + + E+ +LK E+ K+ + E++ + +EEK
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQ-ELKIREQEEKMWRQEEKMHE-QEEK 340
Query: 592 KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEA--RRLRWLQQ 649
++ E K + +EK + +EE++ E++ K +K+ E + + +++EE R+ +++
Sbjct: 341 IREQEDKMWRQEEKIRE-QEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIRE 399
Query: 650 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR-EQER 708
+EE+R+ + Q+KK EQ+ K E + ++E++ RE E Q++ E+ R E++
Sbjct: 400 QEEKRQEKMWRQEKKMREQD--EKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKM 457
Query: 709 REQERQLAEQERR--REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAER 766
+E+E ++ EQE + R++E++Q + E R++ L Q+E++ + E+ ++EE+ E
Sbjct: 458 QEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE 517
Query: 767 QLQEEQEKKAKE 778
++QE++EK ++
Sbjct: 518 KMQEQEEKMQRQ 529
Score = 97.1 bits (240), Expect = 7e-20
Identities = 79/288 (27%), Positives = 156/288 (54%), Gaps = 15/288 (5%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKVEE--DKRRRLEEVKLKREERLRKVLQARERVEQMK 588
+EK R++ E +R +EE + +K+ E +K + EE ++EE++R+ + R+ +
Sbjct: 352 EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQ 411
Query: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
E+K ++ ++K + +E+ + +EE++ E + + +K+ EVE + ++EEE +Q
Sbjct: 412 EKKMREQDEKIREQEEEMWR-QEEKIRELEEMMQDQEEKLREVEEKMQEEEEK-----MQ 465
Query: 649 QEEEE-RRHQELLQKKKEE--EQERLRKAAEAKRLAEQREQERREQERR-EQERREQERR 704
++EE+ +R +E +Q+++E+ QE+L K E ++ EQ E+ R++E+ EQE + QE+
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE--KIWEQEEKMWRQEEKMWEQEEKMQEQE 523
Query: 705 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE-QQRL 763
E+ +R++E+ ++ R +QE E+E++ +E RL K + EL +E QRL
Sbjct: 524 EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583
Query: 764 AERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPP 811
+ E K++EA + + +YQ G A P
Sbjct: 584 PTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALP 631
Score = 95.9 bits (237), Expect = 2e-19
Identities = 85/375 (22%), Positives = 186/375 (49%), Gaps = 45/375 (12%)
Query: 435 DQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRT 494
D+ D E S + K S K+ L +++ +ED + + + K +
Sbjct: 85 DEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNE 144
Query: 495 FLHTVQRNQMLMTP------TSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAE 548
+T ++ ++ P +A + S ++ L D + +E L ++ +A
Sbjct: 145 KNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEET--LHFDHAVRMGTYIEKLTKERDAP 202
Query: 549 QLR--RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKT 606
L R + +++ L+E + +E+LR V + ++ ++ K+++E+ + ++
Sbjct: 203 SLELYRNTITDEE---LKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQ 259
Query: 607 EKAKEERLAEE----KAKKKAAAKKMEEVEARRKQEEEA--RRLRWLQQEEEERRHQELL 660
+ + +RL +E AK +A ++ E +Q+EE R+ +Q++EE+ QEL
Sbjct: 260 LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELK 319
Query: 661 QKKKEEEQERLRKAAEAKRLAEQREQERREQE---RREQERREQE-----------RREQ 706
+++EE+ R + +++ EQ E+ R +++ R+E++ REQE R+E+
Sbjct: 320 IREQEEKMWR-----QEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 707 ERREQERQLAEQERR--REQERLQAERELQE-----REKALRLQKEQLQRELEEKKKKEE 759
+ REQ+ ++ EQE R++E+++ + E ++ +EK +R Q E+++ + EE ++EE
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE 434
Query: 760 QQRLAERQLQEEQEK 774
+ R E +Q+++EK
Sbjct: 435 KIRELEEMMQDQEEK 449
Score = 79.0 bits (193), Expect = 2e-14
Identities = 65/257 (25%), Positives = 141/257 (54%), Gaps = 25/257 (9%)
Query: 529 DPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK 588
+ +E+ ++ E +R +EE Q + + E+ R + E+++ + EE R+ + RE E M+
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
Query: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
++ E+K +++EK ++ +EE++ E++ K + +K++E ++E+ R+ + L+
Sbjct: 445 DQ-----EEKLREVEEKMQE-EEEKMQEQEEKIQRQEEKIQE-----QEEKTWRQEKLLK 493
Query: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE----RREQERREQERR 704
QEE+ +E + +++E+ E+ K E + +++E++ REQE ++E++ +EQE R
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 705 EQERREQERQLAEQE-------RRREQERLQAERELQEREKALRLQKEQ-LQRELEEKKK 756
QE E+ +L ++ R +RL + + E L+ Q+ Q LQ++ + +
Sbjct: 554 LQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVE--LKSQEAQSLQQQQDHYRG 611
Query: 757 KEEQQRLAERQLQEEQE 773
+Q A +QL +E
Sbjct: 612 HLQQYVAAYQQLASGKE 628
Score = 53.1 bits (126), Expect = 1e-06
Identities = 58/257 (22%), Positives = 111/257 (43%), Gaps = 21/257 (8%)
Query: 556 EEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEK----TEKAKE 611
+ED KL+++ ++R + R + + +EK Q+ + A ++ + T++ E
Sbjct: 27 DEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDE 86
Query: 612 ERLAEEKAKKKAAAKKMEEVEARRKQE---EEARRLRWLQQEEEERRHQELLQKKKEEEQ 668
+ EE K + ++ V + E+A + +E + + Q+K E+
Sbjct: 87 DDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKN 146
Query: 669 ERLRKAAEAK----RLAEQREQERREQERREQ----ERREQERREQERREQERQLAEQER 720
RK K RL E Q+R E E+ + + E+ +ER E
Sbjct: 147 YTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLEL 206
Query: 721 RR----EQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE--QQRLAERQLQEEQEK 774
R ++E + ELQE+ + + +K ++Q +++ K+K E Q L ++QLQ E ++
Sbjct: 207 YRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADR 266
Query: 775 KAKEAAGASKALNVTVD 791
KE S L V+
Sbjct: 267 LGKELQSVSAKLQAQVE 283
Score = 51.2 bits (121), Expect = 4e-06
Identities = 72/370 (19%), Positives = 155/370 (41%), Gaps = 29/370 (7%)
Query: 338 RLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNG 397
RL K+ A + + L LLN + +K+ ++++ E+ E + E ++ E
Sbjct: 266 RLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE- 324
Query: 398 NNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRK----RSY 453
W + + E Q+E +Q + RE + R+ R
Sbjct: 325 EKMWRQEE-----KMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQ 379
Query: 454 KQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRP----LRTFLHTVQRNQMLMTPT 509
+ + E +EE ++E+++ K K +R +R + R + +
Sbjct: 380 DEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIREL 439
Query: 510 SAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKV--------EEDKRR 561
+ ++ + +EK +++ E ++R+EE Q + +K +E+K
Sbjct: 440 EEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIW 499
Query: 562 RLEEVKLKREERL---RKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEK 618
EE ++EE++ + +Q +E Q +EEK ++ E + Q +EK ++ +E RL E +
Sbjct: 500 EQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE-QEVRLQELE 558
Query: 619 AKKKAAAKKMEEV--EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRK-AA 675
+ +K E + R + L + Q E + + + LQ++++ + L++ A
Sbjct: 559 ERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVA 618
Query: 676 EAKRLAEQRE 685
++LA +E
Sbjct: 619 AYQQLASGKE 628
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 110 bits (274), Expect = 8e-24
Identities = 79/294 (26%), Positives = 165/294 (56%), Gaps = 20/294 (6%)
Query: 533 KERQRLENLRRKEEAEQLRRQKV--EEDKRRRLEEVKLKREERLR----KVLQARERVEQ 586
K R++ E + R+EE + +K+ +EDK R EE ++EE++R K+ + E++ +
Sbjct: 319 KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE 378
Query: 587 MKEEKKKQIEQKFAQ---IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 643
E+ ++Q E+ + Q I E+ EK +E+ +EK ++ K E+ E +QEE+ R
Sbjct: 379 QDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRE 438
Query: 644 LRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQER 703
L + Q++EE+ + +++K +EE+E++++ E + E++ QE+ E+ R+++ +QE
Sbjct: 439 LEEMMQDQEEKLRE--VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE 496
Query: 704 R--EQER---REQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKE 758
+ EQE R++E+ ++E+ +EQE +E + RE+ +RL +++ + + +E + +E
Sbjct: 497 KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556
Query: 759 EQQRLAERQLQEEQEKKAKEAAGASKALNVT----VDVQSPACTSYQMTPQGHR 808
++RL + + E A +G+ + +T V+++S S Q +R
Sbjct: 557 LEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610
Score = 109 bits (272), Expect = 1e-23
Identities = 91/319 (28%), Positives = 175/319 (54%), Gaps = 33/319 (10%)
Query: 484 PASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRR 543
P + ++ F H V+ + T R + + RNT + KEK + E LR
Sbjct: 171 PENSLLEETLHFDHAVRMGTYIEKLTKE-RDALSLELYRNTITDEELKEKNAELQEKLRL 229
Query: 544 KEEAEQLRRQKVEEDKRRRLEEVKL--------KREERLRKVLQARERVEQMKEEK---- 591
E +E+ Q +D +R+LE +L +RL K LQ+ Q + E+
Sbjct: 230 VE-SEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELW 288
Query: 592 ---KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL---R 645
+Q E+K + +EK ++ +EE++ E++ K + +KM E + ++EE R +
Sbjct: 289 NLLNQQQEEKMWRQEEKIQE-QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
Query: 646 WLQQEEEERRHQELLQKKKEE---EQERLRKAAEAKRLAEQREQERREQER-REQERREQ 701
+QEE+ R +E +++++E+ ++E++R+ E ++ EQ E+ R++E+ REQE + Q
Sbjct: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDE--KIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 702 E---RREQERREQERQLAEQER---RREQERLQAERELQEREKALRLQKEQLQRELEEKK 755
E R+E++ REQ+ ++ EQE R+E++ + E +Q++E+ LR +E++Q E E+ +
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 756 KKEEQQRLAERQLQEEQEK 774
++EE+ + E ++QE++EK
Sbjct: 466 EQEEKIQRQEEKIQEQEEK 484
Score = 107 bits (266), Expect = 7e-23
Identities = 66/256 (25%), Positives = 157/256 (61%), Gaps = 15/256 (5%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKV---EEDKRRRLEEVKLKREERLRKVLQARERVEQM 587
+++E+ + L+ +E+ E++ RQ+ E++++ R +E K+ R+E K+ + E++ +
Sbjct: 308 EQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEE--KIREQEEKIREQ 365
Query: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEV-EARRKQEEEARRLRW 646
+E+ +Q E+K + DEK ++ +EE +E+ ++ K+ E++ +K E+ ++R
Sbjct: 366 EEKMWRQ-EEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR- 423
Query: 647 LQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQ 706
+QEEE R +E +++ +E Q++ K E + ++ E++ +EQE + Q + E+ + ++
Sbjct: 424 -EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQE 482
Query: 707 ERREQERQLAEQERR---REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRL 763
E+ ++ +L +QE + +E++ + E ++ E+E+ ++ Q+E++QR+ E+K +E++ RL
Sbjct: 483 EKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ--EEKMREQEVRL 540
Query: 764 -AERQLQEEQEKKAKE 778
+ + +EQE + +E
Sbjct: 541 WQQEEKMQEQEVRLQE 556
Score = 105 bits (263), Expect = 1e-22
Identities = 70/265 (26%), Positives = 153/265 (57%), Gaps = 17/265 (6%)
Query: 526 LRMDPKEKERQRLENLRRKEE--AEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER 583
L +EK ++ E ++ +EE EQ + + +E+K R EE ++EE++R+ +E
Sbjct: 291 LNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE----QED 346
Query: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 643
+EEK ++ E+K + +EK + +EE++ E+ K + ++M E + +++EE R+
Sbjct: 347 KMWRQEEKIREQEEKIREQEEKMWR-QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 644 LRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE--Q 701
+ +QE++ R E +++++EE + K E + + + +E++ RE E + QE E Q
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 702 ERREQERREQERQLAEQERRREQERL--------QAERELQEREKALRLQKEQLQRELEE 753
E+ E+ +R++E+ ++E+ QE+L + E ++ +E+ + Q+E++Q + E+
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEK 525
Query: 754 KKKKEEQQRLAERQLQEEQEKKAKE 778
+++EE+ R E +L +++EK ++
Sbjct: 526 MQRQEEKMREQEVRLWQQEEKMQEQ 550
Score = 103 bits (256), Expect = 1e-21
Identities = 70/252 (27%), Positives = 151/252 (59%), Gaps = 12/252 (4%)
Query: 534 ERQRLENLRRKEEAEQLRRQ--KVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 591
E L NL +++ E++ RQ K++E + + E+ +LK E+ K+ + E++ + +EEK
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQ-ELKIREQEEKMWRQEEKMHE-QEEK 340
Query: 592 KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEA--RRLRWLQQ 649
++ E K + +EK + +EE++ E++ K +K+ E + + +++EE R+ +++
Sbjct: 341 IREQEDKMWRQEEKIRE-QEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIRE 399
Query: 650 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR-EQER 708
+EE+R+ + Q+KK EQ+ K E + ++E++ RE E Q++ E+ R E++
Sbjct: 400 QEEKRQEKMWRQEKKMREQD--EKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKM 457
Query: 709 REQERQLAEQERR--REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAER 766
+E+E ++ EQE + R++E++Q + E R++ L Q+E++ + E+ ++EE+ E
Sbjct: 458 QEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE 517
Query: 767 QLQEEQEKKAKE 778
++QE++EK ++
Sbjct: 518 KMQEQEEKMQRQ 529
Score = 97.1 bits (240), Expect = 7e-20
Identities = 79/288 (27%), Positives = 156/288 (54%), Gaps = 15/288 (5%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKVEE--DKRRRLEEVKLKREERLRKVLQARERVEQMK 588
+EK R++ E +R +EE + +K+ E +K + EE ++EE++R+ + R+ +
Sbjct: 352 EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQ 411
Query: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
E+K ++ ++K + +E+ + +EE++ E + + +K+ EVE + ++EEE +Q
Sbjct: 412 EKKMREQDEKIREQEEEMWR-QEEKIRELEEMMQDQEEKLREVEEKMQEEEEK-----MQ 465
Query: 649 QEEEE-RRHQELLQKKKEE--EQERLRKAAEAKRLAEQREQERREQERR-EQERREQERR 704
++EE+ +R +E +Q+++E+ QE+L K E ++ EQ E+ R++E+ EQE + QE+
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE--KIWEQEEKMWRQEEKMWEQEEKMQEQE 523
Query: 705 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE-QQRL 763
E+ +R++E+ ++ R +QE E+E++ +E RL K + EL +E QRL
Sbjct: 524 EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583
Query: 764 AERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPP 811
+ E K++EA + + +YQ G A P
Sbjct: 584 PTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALP 631
Score = 95.1 bits (235), Expect = 3e-19
Identities = 85/375 (22%), Positives = 186/375 (49%), Gaps = 45/375 (12%)
Query: 435 DQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRT 494
D+ D E S + K S K+ L +++ +ED + + + K +
Sbjct: 85 DEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNE 144
Query: 495 FLHTVQRNQMLMTP------TSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAE 548
+T ++ ++ P +A + S ++ L D + +E L ++ +A
Sbjct: 145 KNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEET--LHFDHAVRMGTYIEKLTKERDAL 202
Query: 549 QLR--RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKT 606
L R + +++ L+E + +E+LR V + ++ ++ K+++E+ + ++
Sbjct: 203 SLELYRNTITDEE---LKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQ 259
Query: 607 EKAKEERLAEE----KAKKKAAAKKMEEVEARRKQEEEA--RRLRWLQQEEEERRHQELL 660
+ + +RL +E AK +A ++ E +Q+EE R+ +Q++EE+ QEL
Sbjct: 260 LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELK 319
Query: 661 QKKKEEEQERLRKAAEAKRLAEQREQERREQE---RREQERREQE-----------RREQ 706
+++EE+ R + +++ EQ E+ R +++ R+E++ REQE R+E+
Sbjct: 320 IREQEEKMWR-----QEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 707 ERREQERQLAEQERR--REQERLQAERELQE-----REKALRLQKEQLQRELEEKKKKEE 759
+ REQ+ ++ EQE R++E+++ + E ++ +EK +R Q E+++ + EE ++EE
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE 434
Query: 760 QQRLAERQLQEEQEK 774
+ R E +Q+++EK
Sbjct: 435 KIRELEEMMQDQEEK 449
Score = 79.0 bits (193), Expect = 2e-14
Identities = 65/257 (25%), Positives = 141/257 (54%), Gaps = 25/257 (9%)
Query: 529 DPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK 588
+ +E+ ++ E +R +EE Q + + E+ R + E+++ + EE R+ + RE E M+
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
Query: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
++ E+K +++EK ++ +EE++ E++ K + +K++E ++E+ R+ + L+
Sbjct: 445 DQ-----EEKLREVEEKMQE-EEEKMQEQEEKIQRQEEKIQE-----QEEKTWRQEKLLK 493
Query: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE----RREQERREQERR 704
QEE+ +E + +++E+ E+ K E + +++E++ REQE ++E++ +EQE R
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 705 EQERREQERQLAEQE-------RRREQERLQAERELQEREKALRLQKEQ-LQRELEEKKK 756
QE E+ +L ++ R +RL + + E L+ Q+ Q LQ++ + +
Sbjct: 554 LQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVE--LKSQEAQSLQQQQDHYRG 611
Query: 757 KEEQQRLAERQLQEEQE 773
+Q A +QL +E
Sbjct: 612 HLQQYVAAYQQLASGKE 628
Score = 53.1 bits (126), Expect = 1e-06
Identities = 58/257 (22%), Positives = 111/257 (43%), Gaps = 21/257 (8%)
Query: 556 EEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEK----TEKAKE 611
+ED KL+++ ++R + R + + +EK Q+ + A ++ + T++ E
Sbjct: 27 DEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDE 86
Query: 612 ERLAEEKAKKKAAAKKMEEVEARRKQE---EEARRLRWLQQEEEERRHQELLQKKKEEEQ 668
+ EE K + ++ V + E+A + +E + + Q+K E+
Sbjct: 87 DDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKN 146
Query: 669 ERLRKAAEAK----RLAEQREQERREQERREQ----ERREQERREQERREQERQLAEQER 720
RK K RL E Q+R E E+ + + E+ +ER E
Sbjct: 147 YTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLEL 206
Query: 721 RR----EQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE--QQRLAERQLQEEQEK 774
R ++E + ELQE+ + + +K ++Q +++ K+K E Q L ++QLQ E ++
Sbjct: 207 YRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADR 266
Query: 775 KAKEAAGASKALNVTVD 791
KE S L V+
Sbjct: 267 LGKELQSVSAKLQAQVE 283
Score = 51.2 bits (121), Expect = 4e-06
Identities = 72/370 (19%), Positives = 155/370 (41%), Gaps = 29/370 (7%)
Query: 338 RLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNG 397
RL K+ A + + L LLN + +K+ ++++ E+ E + E ++ E
Sbjct: 266 RLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE- 324
Query: 398 NNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRK----RSY 453
W + + E Q+E +Q + RE + R+ R
Sbjct: 325 EKMWRQEE-----KMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQ 379
Query: 454 KQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRP----LRTFLHTVQRNQMLMTPT 509
+ + E +EE ++E+++ K K +R +R + R + +
Sbjct: 380 DEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIREL 439
Query: 510 SAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKV--------EEDKRR 561
+ ++ + +EK +++ E ++R+EE Q + +K +E+K
Sbjct: 440 EEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIW 499
Query: 562 RLEEVKLKREERL---RKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEK 618
EE ++EE++ + +Q +E Q +EEK ++ E + Q +EK ++ +E RL E +
Sbjct: 500 EQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE-QEVRLQELE 558
Query: 619 AKKKAAAKKMEEV--EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRK-AA 675
+ +K E + R + L + Q E + + + LQ++++ + L++ A
Sbjct: 559 ERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVA 618
Query: 676 EAKRLAEQRE 685
++LA +E
Sbjct: 619 AYQQLASGKE 628
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 107 bits (266), Expect = 7e-23
Identities = 55/199 (27%), Positives = 127/199 (63%), Gaps = 6/199 (3%)
Query: 582 ERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEA 641
ER ++ +E +K++ E++ + E+ +K K++R E+ K++ +K E + + ++E+E
Sbjct: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKER 94
Query: 642 RRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQ 701
R+ + +++ E ++ +KKK+E +ER R E K+ E++ ++RR+++RR++ +RE+
Sbjct: 95 RKRKKEKKKRERKQRGRRERKKKKERKERER---ENKQRRERKRKKRRKKKRRKERKREK 151
Query: 702 ERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 761
ER ++ER+ ++R+ E+E++RE+ R + ++E + +E+ R ++ + +R KKK+ ++
Sbjct: 152 ERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER---RKKKERKKD 208
Query: 762 RLAERQLQEEQEKKAKEAA 780
R +RQ + + +E+A
Sbjct: 209 RKTDRQTDSQVFRPLRESA 227
Score = 102 bits (254), Expect = 2e-21
Identities = 63/213 (29%), Positives = 128/213 (60%), Gaps = 19/213 (8%)
Query: 566 VKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAA 625
VKL E ++ + Q + E+KK+ ++ + E+ ++ K ER +EK K+K
Sbjct: 11 VKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRE 70
Query: 626 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQRE 685
+ E E +RK+ E+ R+ ++ E+ERR K+K+E+++R RK R
Sbjct: 71 RGKER-ERKRKEREKQRK----ERREKERR------KRKKEKKKRERKQ-------RGRR 112
Query: 686 QERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKE 745
+ ++++ER+E+ER ++RRE++R+++ ++ +ER+RE+ER + ER+ ++R+K R +K
Sbjct: 113 ERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKR 172
Query: 746 QLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
+ R+ E KK++E ++R ++ ++++ +K KE
Sbjct: 173 ERNRK-ERKKERERKERRERKKERKKERRKKKE 204
Score = 99.0 bits (245), Expect = 2e-20
Identities = 58/215 (26%), Positives = 131/215 (60%), Gaps = 14/215 (6%)
Query: 517 KSFIKRNTPLRMDP-----KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE 571
++ +K NT L+M K ++ E + + E E+ +R++ +E KR R ++ K KR+
Sbjct: 8 RAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRK 67
Query: 572 ERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEV 631
+R R + R+R E+ K+ K+++ +++ + EK ++ +++R E+ KKK ++ E
Sbjct: 68 KRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKEREREN 127
Query: 632 EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 691
+ RR+++ + RR +++R +E ++K+ ++ER RK + + ++RE+ R+E+
Sbjct: 128 KQRRERKRKKRR--------KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKER 179
Query: 692 ERREQERREQERREQERREQERQLAEQERRREQER 726
++E+ER+E+ R++ER+++ R+ E+++ R+ +R
Sbjct: 180 -KKERERKERRERKKERKKERRKKKERKKDRKTDR 213
Score = 91.3 bits (225), Expect = 4e-18
Identities = 63/214 (29%), Positives = 123/214 (57%), Gaps = 17/214 (7%)
Query: 518 SFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLR-RQKVEEDKRRRLE-----EVKLKRE 571
S I + R ++KER+ E +R+ E E+ R R K E+ KR++ E E K K
Sbjct: 23 SHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKER 82
Query: 572 ERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEV 631
E+ RK + +ER ++ KE+KK++ +Q+ + + K +K ++ER E K +++ KK +
Sbjct: 83 EKQRKERREKERRKRKKEKKKRERKQR-GRRERKKKKERKERERENKQRRERKRKKRRKK 141
Query: 632 EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 691
+ R++++ E R + ++ + ++R +E +KK+E R E K+ E++E+ R++
Sbjct: 142 KRRKERKREKERGK--RERKRKKRKKEEREKKRE------RNRKERKKERERKERRERKK 193
Query: 692 ERREQERREQERREQERREQERQLAEQERRREQE 725
ER+++ R+++ER++ R+ +RQ Q R +E
Sbjct: 194 ERKKERRKKKERKKD--RKTDRQTDSQVFRPLRE 225
Score = 53.9 bits (128), Expect = 7e-07
Identities = 30/114 (26%), Positives = 65/114 (57%), Gaps = 1/114 (0%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
+ KER+R RR+ + ++ R++K ++++R E K +R+ + RK + ++ E+ ++E
Sbjct: 119 ERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKE 178
Query: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 644
+KK+ E+K + + K E+ KE R +E+ K + ++ + R +E R+
Sbjct: 179 RKKERERKERR-ERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRV 231
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 103 bits (258), Expect = 6e-22
Identities = 90/286 (31%), Positives = 144/286 (50%), Gaps = 29/286 (10%)
Query: 510 SAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLK 569
S P M++ N + K + RQ + E + ++ D +E K K
Sbjct: 131 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEK 190
Query: 570 REERLRKVLQA---RERVEQMKEEKKKQIEQ-------KFAQIDEKTEKAKEERLAEEKA 619
EE K + +VE M EEK + ++ K QI + K +EER E+ +
Sbjct: 191 EEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEER--EQGS 248
Query: 620 KKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR 679
+ + +KMEE + R + E AR L+ EE ER E + K+ ER R AE K
Sbjct: 249 DEISHHEKMEEEDKERAEAERAR----LEAEERERIKAE---QDKKIADERARIEAEEKA 301
Query: 680 LAEQREQ-ERREQER-REQERREQERREQERREQERQLAEQERRREQERLQAE--RELQE 735
A++RE+ E E+ER RE+E+R E R++ + E++R E++R +E+E+ AE + ++E
Sbjct: 302 AAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKE 361
Query: 736 REKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEE----QEKKAK 777
EK ++++ + E EEK K EEQ+R +QL+E+ QE K K
Sbjct: 362 EEKRAAEERQRARAEEEEKAKVEEQKR--NKQLEEKKHAMQETKIK 405
Score = 99.8 bits (247), Expect = 1e-20
Identities = 92/399 (23%), Positives = 189/399 (47%), Gaps = 41/399 (10%)
Query: 410 NSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDE-EQHLED 468
NS P+ + ++ T G EA + RE RR++ ++A+ E + + D
Sbjct: 72 NSVPDEEAKTTTTNTQVEGDDEAAFLERLARREE----RRQKRLQEALERQKEFDPTITD 127
Query: 469 EELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRM 528
L P + + + ++ + Q + + +S K+ + +
Sbjct: 128 ASLSLPSRRMQNDTAENETTEKEEKS--ESRQERYEIEETETVTKSYQKNDWRDAEENKK 185
Query: 529 DPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL-------------KREERLR 575
+ KEKE + E +R E VEE EE + K+EE
Sbjct: 186 EDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEERE 245
Query: 576 KVLQARERVEQMKEEKKKQIEQKFAQID----EKTEKAKEERLAEEKAKKKAAAKKMEEV 631
+ E+M+EE K++ E + A+++ E+ + +++++A+E+A+ +A K +
Sbjct: 246 QGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQ- 304
Query: 632 EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 691
E R++ EE R+R EEE+R E Q+ KEEE+ R A E +R+ E+ ++ E+
Sbjct: 305 ERERREAEERERMR-----EEEKRAAEERQRIKEEEK---RAAEERQRIKEEEKRAAEER 356
Query: 692 ER-REQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRE 750
+R +E+E+R E R++ R E+E + +E++R ++ + + +QE +++ E+++++
Sbjct: 357 QRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQE----TKIKGEKVEQK 412
Query: 751 LEEK---KKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 786
+E K +KK ++ +L L+++ E+K + + L
Sbjct: 413 IEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKL 451
Score = 94.4 bits (233), Expect = 4e-19
Identities = 101/419 (24%), Positives = 190/419 (45%), Gaps = 36/419 (8%)
Query: 357 SYLERLLNVEVP-QKVGSEQKEPPEEAEP-VAAAEPEVPENNGNNSWPHNDTEIANSTPN 414
++LERL E QK E E +E +P + A +P N N+T T
Sbjct: 95 AFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET-----TEK 149
Query: 415 PKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPP 474
+ + S E + E T + +K ++ A E++ E+EE + P
Sbjct: 150 EEKSESRQERYEIEETETVT-----------KSYQKNDWRDAEENKKEDKEKEEEEEEKP 198
Query: 475 RSKTPSSPCPASKVVRPL-----RTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMD 529
+ + V T + +++ Q+ + + + +M+
Sbjct: 199 KRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKME 258
Query: 530 PKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKE 589
++KER E R + EAE+ R K E+DK+ E +++ EE+ Q RER E +
Sbjct: 259 EEDKERAEAE--RARLEAEERERIKAEQDKKIADERARIEAEEKA--AAQERERREAEER 314
Query: 590 EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 649
E+ ++ E+K A + + K +E+R AEE+ + K K+ E R K+EE+
Sbjct: 315 ERMRE-EEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKR------AA 367
Query: 650 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERR 709
EE +R E +K K EEQ+R ++ E K ++ + + + E++ + + E++ QE +
Sbjct: 368 EERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDK 427
Query: 710 EQERQLAEQERRREQERLQAERE-LQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQ 767
Q L +Q + ++QA+RE LQE + + ++ + ++ ++K+ KEE + +R+
Sbjct: 428 LQTAVLKKQGEEK-GTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRK 485
Score = 90.5 bits (223), Expect = 6e-18
Identities = 109/442 (24%), Positives = 194/442 (43%), Gaps = 40/442 (9%)
Query: 370 KVGSEQKEPPEEAEPVAAA--EPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSA 427
K ++KE EE +P + E +V + + + S N + ++ P+
Sbjct: 184 KKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEE 243
Query: 428 GQQEA-------KTDQADGPREPPQSARRKRSYKQAVSE------LDEEQHLEDEELQPP 474
+Q + K ++ D R + AR + ++ + DE +E EE
Sbjct: 244 REQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAA 303
Query: 475 RSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKE 534
+ + ++ + QR + + R +K KR R KE+E
Sbjct: 304 QERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEE 363
Query: 535 RQRLENLRRKEEAEQLRRQKVEEDKR-RRLEEVKLKREERLRKVLQARERVEQMKEEKKK 593
++ E R++ AE+ + KVEE KR ++LEE K +E K + +++E +KK
Sbjct: 364 KRAAEE-RQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKK 422
Query: 594 QIEQKFA------QIDEKTEK--AKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 645
E K Q +EK K AK E+L E+K K K E+++ ++ +EE +
Sbjct: 423 AQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFM 482
Query: 646 WLQQEEEERRHQE---LLQKKKEEEQERLRKAAEAKRLAEQREQERREQ----ERREQER 698
++ E + Q + K K E R A + +E E Q +R E+ R
Sbjct: 483 DRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRAS--VDTKEAEGAPQVEAGKRLEELR 540
Query: 699 REQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKE 758
R + E E E+ +Q +QE E E L+ +RE ER K L ++++ ++E ++K +E
Sbjct: 541 RRRGETESEEFEKLKQ-KQQEAALELEELKKKRE--ERRKVLEEEEQRRKQEEADRKLRE 597
Query: 759 EQQRLAERQLQEEQEKKAKEAA 780
E+++ R+L+EE E++ EAA
Sbjct: 598 EEEK---RRLKEEIERRRAEAA 616
Score = 83.2 bits (204), Expect = 1e-15
Identities = 90/379 (23%), Positives = 164/379 (43%), Gaps = 31/379 (8%)
Query: 370 KVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPN----PKPAASSPETP 425
++ +K E+ E A + D +IA+ K AA E
Sbjct: 250 EISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERR 309
Query: 426 SAGQQEAKTDQADGPREPPQSARRKRSYKQAVSE---LDEEQHLEDEELQ--PPRSKTPS 480
A ++E ++ E Q R K K+A E + EE+ EE Q K +
Sbjct: 310 EAEERERMREEEKRAAEERQ--RIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAA 367
Query: 481 SPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLR---MDPKEKERQR 537
++ + + +RN+ L A + K + ++ K+ + +
Sbjct: 368 EERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDK 427
Query: 538 LENLRRKEEAE------QLRRQKVEEDKRR-RLEEVKLKREERLRKVLQARERVEQMKEE 590
L+ K++ E Q +R+K++EDK + EE+K +E+++K + +E V+ +
Sbjct: 428 LQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIK---DEKIKKDKEPKEEVKSFMDR 484
Query: 591 KKKQIEQKFAQIDEKTEKAK--EERLAEEKAKKKAAAKKME---EVEARRKQEEEARRLR 645
KK E K + T K K E + + K+ E +VEA ++ EE RR
Sbjct: 485 KKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRG 544
Query: 646 WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERRE 705
+ EE E+ Q+ Q++ E E L+K E +R + E++RR+QE +++ RE+E +
Sbjct: 545 ETESEEFEKLKQK--QQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKR 602
Query: 706 QERREQERQLAEQERRREQ 724
+ + E ER+ AE +R++
Sbjct: 603 RLKEEIERRRAEAAEKRQK 621
Score = 80.9 bits (198), Expect = 5e-15
Identities = 74/293 (25%), Positives = 128/293 (43%), Gaps = 51/293 (17%)
Query: 531 KEKERQRLENLRRKEEAEQLRR------------------------QKVEEDKRRRLEEV 566
+ + R R E LR+K+E E L + +VE D E
Sbjct: 40 ERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLER 99
Query: 567 KLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAK 626
+REER +K LQ E +E+ KE + + + + E EK +K + +
Sbjct: 100 LARREERRQKRLQ--EALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQ 157
Query: 627 KMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ 686
+ E+E + ++ W EE ++ +E K+EEE+E+ ++ + + E +
Sbjct: 158 ERYEIEETETVTKSYQKNDWRDAEENKKEDKE----KEEEEEEKPKRGSIGENQVEVMVE 213
Query: 687 ERREQERRE-------------QERREQERREQ---ERREQERQLAEQERRREQERLQAE 730
E+ + + E +E +++E REQ E E+ E + R E ER + E
Sbjct: 214 EKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLE 273
Query: 731 RELQEREKA---LRLQKEQLQRELEEKKKKEEQQR--LAERQLQEEQEKKAKE 778
E +ER KA ++ E+ + E EEK +E++R ER+ E+EK+A E
Sbjct: 274 AEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAE 326
Score = 77.0 bits (188), Expect = 7e-14
Identities = 80/339 (23%), Positives = 160/339 (47%), Gaps = 97/339 (28%)
Query: 531 KEKERQRLENLRRKEEAEQLRRQKVEED-------KRRRLEEVKLKREERLRKVLQARER 583
+E RQ+ E +R EAE++ Q+ ++D +RRR + +L++++ + Q ++
Sbjct: 8 RELRRQKREEMRL--EAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQ 65
Query: 584 VE-----QMKEEKKK------QIE--------QKFAQIDEKTEKAKEERLAEEK------ 618
VE + +E+ K Q+E ++ A+ +E+ +K +E L +K
Sbjct: 66 VEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTI 125
Query: 619 --AKKKAAAKKME----EVEARRKQEE-EARRLR-----------------WLQQEEEER 654
A +++M+ E E K+E+ E+R+ R W EE ++
Sbjct: 126 TDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKK 185
Query: 655 RHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE-------------QERREQ 701
+E K+EEE+E+ ++ + + E +E+ + + E +E +++
Sbjct: 186 EDKE----KEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQE 241
Query: 702 ERREQ---------ERREQERQLAEQERRR----EQERLQAERE---------LQEREKA 739
E REQ + E++++ AE ER R E+ER++AE++ ++ EKA
Sbjct: 242 EEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKA 301
Query: 740 LRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
++E+ + E E+ ++EE++ ERQ +E+EK+A E
Sbjct: 302 AAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAE 340
Score = 68.2 bits (165), Expect = 3e-11
Identities = 72/278 (25%), Positives = 122/278 (43%), Gaps = 49/278 (17%)
Query: 545 EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK--KKQIEQKFAQI 602
E +LRRQK EE R E + +R + + ARER + ++E+ +KQ E+ Q+
Sbjct: 5 ERRRELRRQKREE-MRLEAERIAYQRNDDDEEEA-ARERRRRARQERLRQKQEEESLGQV 62
Query: 603 DEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK 662
++ E + + +E+AK ++E ++EA L L + EE R Q+ LQ+
Sbjct: 63 TDQVEVNAQNSVPDEEAKTTTTNTQVEG-------DDEAAFLERLARREERR--QKRLQE 113
Query: 663 KKEEEQE---------------RLRKAAEAKRLAEQREQERREQERREQER--------- 698
E ++E R++ E+ E+ QER E E
Sbjct: 114 ALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQ 173
Query: 699 ----REQERREQERREQERQLAEQERRREQERLQAE-------RELQEREKALRLQKEQL 747
R+ E ++E +E+E + E+ +R Q E E QE + L+ Q+
Sbjct: 174 KNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQI 233
Query: 748 QRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKA 785
E E K+++E +Q E E+ E++ KE A A +A
Sbjct: 234 SSE-EPKQEEEREQGSDEISHHEKMEEEDKERAEAERA 270
Score = 47.4 bits (111), Expect = 6e-05
Identities = 38/152 (25%), Positives = 76/152 (50%), Gaps = 16/152 (10%)
Query: 651 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 710
++ R +EL ++K+EE + EA+R+A QR + E+ RE+ RR ++ R ++++E
Sbjct: 2 DDFERRRELRRQKREEMR------LEAERIAYQRNDDDEEEAARERRRRARQERLRQKQE 55
Query: 711 QERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQE 770
+E + +Q + A+ + + E Q++ + E +RLA R +E
Sbjct: 56 EE----SLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDE----AAFLERLARR--EE 105
Query: 771 EQEKKAKEAAGASKALNVTVDVQSPACTSYQM 802
++K+ +EA K + T+ S + S +M
Sbjct: 106 RRQKRLQEALERQKEFDPTITDASLSLPSRRM 137
Score = 41.2 bits (95), Expect = 0.004
Identities = 75/368 (20%), Positives = 144/368 (39%), Gaps = 46/368 (12%)
Query: 327 KQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKEPPEEAEPVA 386
K+E R+ A+ EE A + LE + K+ E+ E E + V
Sbjct: 360 KEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVN 419
Query: 387 AAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQS 446
E + E+ + E + K + P+ ++E K ++ +EP +
Sbjct: 420 --EKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEE 477
Query: 447 AR----RKRSYKQAVSELDEE-----QHLEDEELQPP-RSKTPSSPCPASKVVRPLRTFL 496
+ RK+ + + S+ E +H E+ +P R+ + + V + L
Sbjct: 478 VKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKR-L 536
Query: 497 HTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVE 556
++R + + ++ ++ +E +++R E + EE EQ R+Q+ E
Sbjct: 537 EELRRRR-----GETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE-E 590
Query: 557 EDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAE 616
D+ KL+ EE R++ K++IE++ A+ EK +K E+ L++
Sbjct: 591 ADR-------KLREEEEKRRL--------------KEEIERRRAEAAEKRQKMPEDGLSD 629
Query: 617 EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE--ERRHQELLQKKKEEEQERLRKA 674
+K K K + K EE A L Q+ + HQ + K + E+ A
Sbjct: 630 DKKPFKCFTPKGSSL----KIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSA 685
Query: 675 AEAKRLAE 682
E + A+
Sbjct: 686 IEGTKSAK 693
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 102 bits (253), Expect = 2e-21
Identities = 100/387 (25%), Positives = 182/387 (47%), Gaps = 34/387 (8%)
Query: 418 AASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSK 477
A + + + ++EAK Q R + RR+ + AV +++ +++E Q +S
Sbjct: 1376 AEAHAQAKAQAEREAKELQQ---RMQEEVVRREEA---AVDAQQQKRSIQEELQQLRQSS 1429
Query: 478 TPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQR 537
A + R+ L + +++ A LR +E E Q+
Sbjct: 1430 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1489
Query: 538 LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERL--------RKVLQARERVEQMKE 589
+ +EEAE+LRRQ +E +R+R EV+L + ++ LQA E + E
Sbjct: 1490 RQ---AQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1546
Query: 590 EKKKQIEQ----KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 645
E ++++ Q + Q+ E A+ AE ++K+ + A+K ++E R +EE +
Sbjct: 1547 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE--RSLQEEHVAVA 1604
Query: 646 WLQQEEEERRHQELLQKKKEEEQER-----LRKAAEAKRL---AEQREQERREQERREQE 697
L++E E R Q+ ++ EE ER KA EA RL AE+ Q++ + ++
Sbjct: 1605 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1664
Query: 698 RREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
++E+ RE RR + + A ++R ++ L+ +R+L E RL EQ L + ++
Sbjct: 1665 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQ 1724
Query: 758 EEQQRLAERQLQEEQEKKAKEAAGASK 784
EQQR + L+EE + +EAA A++
Sbjct: 1725 GEQQR---QLLEEELARLQREAAAATQ 1748
Score = 96.7 bits (239), Expect = 9e-20
Identities = 150/595 (25%), Positives = 258/595 (43%), Gaps = 118/595 (19%)
Query: 296 SRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAK-QESVVRRASRRL----AKKTAEEPAAS 350
+ + QS R S ++ + L +++ VA+ +E RRA ++ A++ AE
Sbjct: 1574 AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELER 1633
Query: 351 GRIICHSYLE-RLLNVEVPQKVG---SEQKEPPEEAEPVA-----AAEPEVPENNGNNSW 401
++ + L RL EV Q+ +E ++ EEAE A A E V +
Sbjct: 1634 WQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE 1693
Query: 402 PHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELD 461
++A T + AA + A+T+Q + R+ + R ++A +
Sbjct: 1694 LEKQRQLAEGTAQQRLAAEQELI----RLRAETEQGEQQRQLLEE-ELARLQREAAAATQ 1748
Query: 462 EEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIK 521
+ Q LE EL R++ ++ R+ T ++++ + A + +
Sbjct: 1749 KRQELE-AELAKVRAEMEVLLASKARAEEESRS---TSEKSKQRL---EAEAGRFRELAE 1801
Query: 522 RNTPLRMDPKEKERQRL----ENLRRKEEAEQLRRQKV----EEDKRRRLEEVKLKREE- 572
LR +E +RQR + R++ EAE++ +K+ E + + E+ LK +E
Sbjct: 1802 EAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEA 1861
Query: 573 ---RLRKVLQ----ARERVEQMKEEKKKQIEQKFAQI----DEKTEKAK----------- 610
RLR++ + R R+E+ + K IE++ AQ+ D + E+ K
Sbjct: 1862 ENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1921
Query: 611 ---EERLAEEKAKKKAAAKKME--------------EVEARRKQEEEARRLRWLQQEEEE 653
EE LA + + +KAAA K E + ++ + E EA R R L EEE
Sbjct: 1922 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1981
Query: 654 RRHQ--ELLQKK--KEEEQERLRKAA------------EAKRLAEQREQERREQ------ 691
RR + E +QK EEE R RKAA EA+RL E+ EQE Q
Sbjct: 1982 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2041
Query: 692 -----------------ERREQERREQERREQERREQERQLAEQERR----REQERLQAE 730
+++EQE ++ ++EQ +Q R AE RR E+ R+QAE
Sbjct: 2042 AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE 2101
Query: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKA 785
RE + + + + E+L++ EE+ + Q + A +L++E E++A A A +A
Sbjct: 2102 REAAQSRRQVE-EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQA 2155
Score = 94.4 bits (233), Expect = 4e-19
Identities = 75/243 (30%), Positives = 127/243 (52%), Gaps = 22/243 (9%)
Query: 539 ENLRRKEEAE---QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI 595
+ LR KE+AE +RQ E++RRR E EER++K L A E + ++ +++
Sbjct: 1957 DTLRSKEQAELEAARQRQLAAEEERRRREA-----EERVQKSLAAEEEAARQRKAALEEV 2011
Query: 596 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 655
E+ A+++E + ER +E A++ A +E +R Q EE +QQ+E+E
Sbjct: 2012 ERLKAKVEEA--RRLRERAEQESARQLQLA---QEAAQKRLQAEEKAHAFAVQQKEQEL- 2065
Query: 656 HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQ----ERREQERREQ 711
Q+ LQ+++ + +A A+R AE+ E+ R + ER + R Q ER +Q EQ
Sbjct: 2066 -QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2124
Query: 712 ERQLAEQERRREQERLQAERELQER---EKALRLQKEQLQRELEEKKKKEEQQRLAERQL 768
+ A+ + E+ R +AE+E R E+A QK+ E+E+ KK EQ + Q+
Sbjct: 2125 AQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2184
Query: 769 QEE 771
++E
Sbjct: 2185 EQE 2187
Score = 93.6 bits (231), Expect = 8e-19
Identities = 87/327 (26%), Positives = 161/327 (49%), Gaps = 29/327 (8%)
Query: 531 KEKERQRLENLRRKEEA--EQLRRQKVEEDKRRRL---EEVKLKREERLRKVLQARERVE 585
+ KE+ LE R+++ A E+ RR++ EE ++ L EE +R+ L +V + + +VE
Sbjct: 1960 RSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE 2019
Query: 586 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE------ 639
+ + +++ ++ Q+ E A++ AEEKA A +K +E++ +QE+
Sbjct: 2020 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2079
Query: 640 --EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 697
EA R +E EE R +Q ++E Q R R+ EA+RL +Q +E+ + + Q
Sbjct: 2080 RGEAEAARRAAEEAEEAR----VQAEREAAQSR-RQVEEAERL-KQSAEEQAQARAQAQA 2133
Query: 698 RREQERREQERREQERQLAEQERRREQERLQAERELQER--EKALRLQKEQLQRELEEKK 755
E+ R+E E+ R AEQ R+++ AE E ++ E+ LR QK Q+++EL +
Sbjct: 2134 AAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR-QKAQVEQELTTLR 2192
Query: 756 KKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKINP 815
+ E+ + L EE ++ EA A++ + V+ + + + +I
Sbjct: 2193 LQLEETDHQKNLLDEELQRLKAEATEAARQRS---QVEEELFSVRVQMEELSKLKARIEA 2249
Query: 816 DNYGMDLNSDDST----DDEAHPRKPI 838
+N + L D+T +EA K +
Sbjct: 2250 ENRALILRDKDNTQRFLQEEAEKMKQV 2276
Score = 89.0 bits (219), Expect = 2e-17
Identities = 77/277 (27%), Positives = 135/277 (48%), Gaps = 18/277 (6%)
Query: 513 RSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE 572
R + ++ + + KE +++ E + R+EEA ++ KR EE++ R+
Sbjct: 1373 RQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV----DAQQQKRSIQEELQQLRQS 1428
Query: 573 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 632
++ QA+ R + E + +IE++ + + E + +R E + +A + EE E
Sbjct: 1429 SEAEI-QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAE-GELQALRARAEEAE 1486
Query: 633 A--RRKQEEEARRLRWLQQEEEERRHQ---ELLQKKKEE-----EQERLRKAAEAKRLAE 682
A R+ Q EEA RLR Q+E +R+ Q EL + K E E++R +A E RL
Sbjct: 1487 AQKRQAQ-EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQA 1545
Query: 683 QREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRL 742
+ + R Q E+ R+ Q E +R E +L + ++ Q ER LQE A+
Sbjct: 1546 EEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ 1605
Query: 743 QKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 779
+E+ +R +++ + E + AER+L E + KA EA
Sbjct: 1606 LREEAERRAQQQAEAERAREEAEREL-ERWQLKANEA 1641
Score = 87.4 bits (215), Expect = 5e-17
Identities = 138/560 (24%), Positives = 235/560 (41%), Gaps = 117/560 (20%)
Query: 316 QVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQ 375
Q L Q+ S++ + A+RR A++ E + R S R E + S +
Sbjct: 2067 QTLQQEQSVLDQLRGEAE-AARRAAEEAEEARVQAEREAAQS---RRQVEEAERLKQSAE 2122
Query: 376 KEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTD 435
++ A+ AAAE E + E A + A + A ++ K
Sbjct: 2123 EQAQARAQAQAAAEKLRKEA---------EQEAARRAQAEQAALRQKQAADAEMEKHKKF 2173
Query: 436 QADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTF 495
R+ Q + + + + E D +++L DEELQ +++ + S+V L +
Sbjct: 2174 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2233
Query: 496 LHTVQRNQMLMTPTSAPRSVMKSFIKRNTP-LRMDPKEKERQRLENLRR----KEEAEQL 550
++ L A + K NT + EK +Q E R +EA +L
Sbjct: 2234 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2293
Query: 551 RRQKVEED--KRRRLEEVKLKREERLRKVLQAR------ERVEQMKE----------EKK 592
R Q EED ++R L E LK E+++ V +A E ++Q KE E K
Sbjct: 2294 R-QLAEEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK 2350
Query: 593 KQIEQKFAQIDE---KTEKAKEERLAEEKAKKKAAAKKMEEVE-ARRKQEEEARRLRWLQ 648
+Q+ Q+ A+ + +T +A+ +R E A+ + ++ E+ A+ + EE+A+R R
Sbjct: 2351 EQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQA 2410
Query: 649 QEEEERRHQ---------------ELLQKKKEEEQERLRKA-AEAKRLAEQREQERR--- 689
+E E+ H+ E+ +++ + + ERLR+A AE +R E+ +QE +
Sbjct: 2411 EEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2470
Query: 690 ---------------------------------------EQERREQER-------REQER 703
EQE+ + E+ + Q+
Sbjct: 2471 LKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL 2530
Query: 704 REQERREQERQLAEQERRR------EQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
RE+++R+Q++ EQER+R E R Q E E R K LQ+ + QR +E+
Sbjct: 2531 REEQQRQQQQM--EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLA 2588
Query: 758 EEQQRLAER-QLQEEQEKKA 776
EE QRL E+ QL EEQ + A
Sbjct: 2589 EENQRLREQLQLLEEQHRAA 2608
Score = 86.7 bits (213), Expect = 9e-17
Identities = 98/403 (24%), Positives = 185/403 (45%), Gaps = 53/403 (13%)
Query: 445 QSARRKRSYKQAVSELDEEQHLED--------EELQPPRSKTPSSPCPASKVVRPLRTFL 496
Q ARR++ QA+ D + E EE++ K A + + ++ +
Sbjct: 1224 QDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYE 1283
Query: 497 HTVQRNQMLMTPTSAP------RSVMKSFIKRNTPLRMDPKEKERQRL-------ENLRR 543
+ + + P ++P +S +S I+ LR E E LRR
Sbjct: 1284 LQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRR 1343
Query: 544 KEEAEQLRRQKVEEDKRRRLE-EVKLKREERLRKV-LQARERVEQMKEEKKKQIEQKFAQ 601
EE E+L Q+ E++ R E E L+++ +L + QA+ + E+ +E +++++++ +
Sbjct: 1344 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1403
Query: 602 IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQ 661
+E A++++ + ++ ++ E++A+ +Q E A R R L+ EEE R +
Sbjct: 1404 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR-LRIEEEIR-----VV 1457
Query: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 721
+ + E ER R AE E + R +E Q+R+ QE E+ RR Q+ ++ +R
Sbjct: 1458 RLQLEATERQRGGAEG----ELQALRARAEEAEAQKRQAQEEAERLRR----QVQDESQR 1509
Query: 722 REQ------ERLQAERE-LQEREKA------LRLQKEQLQREL---EEKKKKEEQQRLAE 765
+ Q R++AE E +E+++A LRLQ E+ +R L E ++ ++ Q L
Sbjct: 1510 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALET 1569
Query: 766 RQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHR 808
Q E E ++K A+ A K + +Q Q+ + R
Sbjct: 1570 AQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER 1612
Score = 86.7 bits (213), Expect = 9e-17
Identities = 120/544 (22%), Positives = 218/544 (40%), Gaps = 79/544 (14%)
Query: 299 DSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSY 358
+SQ R + + +S +V A+ + KQ ++ RL + AE R + +
Sbjct: 1506 ESQRKRQAEVELAS---RVKAEAEAAREKQRALQALEELRLQAEEAE------RRLRQAE 1556
Query: 359 LERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPA 418
+ER V+V + E +++ + AE S +A +
Sbjct: 1557 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER---SLQEEHVAVAQLREEAERR 1613
Query: 419 ASSPETPSAGQQEA---------KTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDE 469
A ++EA K ++A R + +++S QA +E +E E E
Sbjct: 1614 AQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKE---EAE 1670
Query: 470 ELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMD 529
R K + VR +++ + L T+ R + + R LR +
Sbjct: 1671 REARRRGKAEE------QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR---LRAE 1721
Query: 530 PKEKERQR------LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER 583
++ E+QR L L+R+ A +RQ++E + L +V+ + E L +A E
Sbjct: 1722 TEQGEQQRQLLEEELARLQREAAAATQKRQELEAE----LAKVRAEMEVLLASKARAEEE 1777
Query: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE--- 640
E+ K+++E + + E E+A R E+AK++ + EE AR++ E E
Sbjct: 1778 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQR--QLAEEDAARQRAEAERVL 1835
Query: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
A +L + + + E+ K+KE E ERLR+ AE + +R +E+ Q + + E R
Sbjct: 1836 AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL 1895
Query: 701 QERREQERREQERQLA------EQERRREQE-------------------------RLQA 729
+ R+ E ERQ Q R+ E+E R A
Sbjct: 1896 AQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA 1955
Query: 730 ERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVT 789
E L+ +E+A Q Q EE++++ E + ++ L E+E + A + +
Sbjct: 1956 EDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLK 2015
Query: 790 VDVQ 793
V+
Sbjct: 2016 AKVE 2019
Score = 82.8 bits (203), Expect = 1e-15
Identities = 119/525 (22%), Positives = 224/525 (42%), Gaps = 92/525 (17%)
Query: 319 AQKYSLVAKQESVVRRASRRLAKK-TAEEPAASGRIICHSYLERLL-------------- 363
A++ L A++E R A R+ K AEE AA R +ERL
Sbjct: 1970 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2029
Query: 364 -----NVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPA 418
+++ Q+ ++ + E+A A + E + + + + A
Sbjct: 2030 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE---QELQQTLQQEQSVLDQLRGEAEAA 2086
Query: 419 ASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKT 478
+ E + +A+ + A R+ ++ R K+S ++ + Q ++ + +
Sbjct: 2087 RRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2146
Query: 479 PSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRL 538
+R + +++++ T ++ ++ + T LR+ +E + Q+
Sbjct: 2147 ARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQEL---TTLRLQLEETDHQKN 2203
Query: 539 ---ENLRR-KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 594
E L+R K EA + RQ+ + ++ V+++ +L+ ++A R +++ K
Sbjct: 2204 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD---KD 2260
Query: 595 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 654
Q+F Q E+ EK K+ +AEE A+ AA +EA RLR L +E+ +
Sbjct: 2261 NTQRFLQ--EEAEKMKQ--VAEEAARLSVAA-------------QEAARLRQLAEEDLAQ 2303
Query: 655 RH---QELLQKKKEEEQERLRKAAEAKRLAEQR----EQERREQERREQERRE------- 700
+ +++L++K + QE R AEA+ L +Q+ EQ RR QE +EQ ++
Sbjct: 2304 QRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2363
Query: 701 -QERREQERREQERQLAEQER-------------RREQE----RLQAER--------ELQ 734
Q E ER+ Q AE ER R E++ R QAE EL
Sbjct: 2364 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2423
Query: 735 EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 779
+EK +Q ++QR+ + + ++ +AE L+ E+EK +EA
Sbjct: 2424 TQEKVTLVQTLEIQRQQSDHDAERLREAIAE--LEREKEKLQQEA 2466
Score = 75.1 bits (183), Expect = 3e-13
Identities = 70/275 (25%), Positives = 129/275 (46%), Gaps = 16/275 (5%)
Query: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL--KREERLRKVLQARERVEQMKE 589
E ERQR + + E +LR ++ + R E+ + K+ E + + L E Q K
Sbjct: 2369 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKV 2428
Query: 590 EKKKQIEQKFAQIDEKTEKAKEE--RLAEEKAKKKAAAK--KMEEVEARRKQEEEARRLR 645
+ +E + Q D E+ +E L EK K + AK +++ E + Q+E+ +
Sbjct: 2429 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQET 2488
Query: 646 WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR- 704
Q+ LLQ+++ EQE+ + + + +Q R EQ+R++Q+ ++ +R
Sbjct: 2489 QALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRL 2548
Query: 705 ---EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 761
+E R ++ + E RR+++E Q E++ +++E+ L E+ QR E+ + EEQ
Sbjct: 2549 VASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL---AEENQRLREQLQLLEEQH 2605
Query: 762 RLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPA 796
R A L +E A + A N + PA
Sbjct: 2606 RAA---LAHSEEVTASQVAATKTLPNGRDALDGPA 2637
Score = 65.5 bits (158), Expect = 2e-10
Identities = 80/345 (23%), Positives = 153/345 (44%), Gaps = 46/345 (13%)
Query: 433 KTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPL 492
+T +A+ R+ SA +R K V+E+ Q +E+ Q R + A ++ L
Sbjct: 2366 RTLEAERQRQLEMSAEAER-LKLRVAEMSRAQARAEEDAQRFRKQ-------AEEIGEKL 2417
Query: 493 -RTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLR 551
RT L T ++ ++ T ++ + + +RL + E E+ +
Sbjct: 2418 HRTELATQEKVTLVQT----------------LEIQRQQSDHDAERLREAIAELEREKEK 2461
Query: 552 RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 611
Q+ + + + EE++ ++E+L LQ + ++Q +K + Q+ I++ EKAK
Sbjct: 2462 LQQEAKLLQLKSEEMQTVQQEQL---LQETQALQQSFLSEKDSLLQRERFIEQ--EKAKL 2516
Query: 612 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERL 671
E+L +++ K A+++ E + R++Q+ E R R + EE RR Q ++ +QE L
Sbjct: 2517 EQLFQDEVAK---AQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL 2573
Query: 672 RKAAEAKRLAEQREQERREQERREQERREQERRE-QERREQERQLAEQERRREQERLQAE 730
+Q EQ+RR+QE E ++ R + Q EQ R ++ A
Sbjct: 2574 ----------QQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAAT 2623
Query: 731 RELQEREKAL--RLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE 773
+ L AL + + + + ++K QRL E + +E
Sbjct: 2624 KTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEE 2668
Score = 47.4 bits (111), Expect = 6e-05
Identities = 61/278 (21%), Positives = 128/278 (46%), Gaps = 35/278 (12%)
Query: 541 LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR---KVLQARERVEQMKEEKKKQIEQ 597
+R + AE++ R E+ K + L E + K L+A+ +Q + + +
Sbjct: 1095 IRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELR 1154
Query: 598 KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA--------RRKQEEEARRLRWLQQ 649
++ E+ ++ ER E + ++ A+ +E +A +R+ E+ R+LR+ +
Sbjct: 1155 GAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYR- 1213
Query: 650 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR--EQERREQERREQERREQE 707
E + L ++ +EQ + A+++ + EQ QE+ E+ R E+ E+ +R +
Sbjct: 1214 ESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAK 1273
Query: 708 R-----REQERQLAEQERRRE-------QERLQ--AERELQE-------REKALRLQKEQ 746
+ ++ E QL + + E + ++Q +E +QE + L +
Sbjct: 1274 QYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQY 1333
Query: 747 LQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 784
++ E ++ EE++RLAE+Q EE+E+ A+ A K
Sbjct: 1334 IKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEK 1371
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 102 bits (253), Expect = 2e-21
Identities = 100/387 (25%), Positives = 182/387 (47%), Gaps = 34/387 (8%)
Query: 418 AASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSK 477
A + + + ++EAK Q R + RR+ + AV +++ +++E Q +S
Sbjct: 1380 AEAHAQAKAQAEREAKELQQ---RMQEEVVRREEA---AVDAQQQKRSIQEELQQLRQSS 1433
Query: 478 TPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQR 537
A + R+ L + +++ A LR +E E Q+
Sbjct: 1434 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1493
Query: 538 LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERL--------RKVLQARERVEQMKE 589
+ +EEAE+LRRQ +E +R+R EV+L + ++ LQA E + E
Sbjct: 1494 RQ---AQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1550
Query: 590 EKKKQIEQ----KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 645
E ++++ Q + Q+ E A+ AE ++K+ + A+K ++E R +EE +
Sbjct: 1551 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE--RSLQEEHVAVA 1608
Query: 646 WLQQEEEERRHQELLQKKKEEEQER-----LRKAAEAKRL---AEQREQERREQERREQE 697
L++E E R Q+ ++ EE ER KA EA RL AE+ Q++ + ++
Sbjct: 1609 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1668
Query: 698 RREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
++E+ RE RR + + A ++R ++ L+ +R+L E RL EQ L + ++
Sbjct: 1669 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQ 1728
Query: 758 EEQQRLAERQLQEEQEKKAKEAAGASK 784
EQQR + L+EE + +EAA A++
Sbjct: 1729 GEQQR---QLLEEELARLQREAAAATQ 1752
Score = 96.7 bits (239), Expect = 9e-20
Identities = 150/595 (25%), Positives = 258/595 (43%), Gaps = 118/595 (19%)
Query: 296 SRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAK-QESVVRRASRRL----AKKTAEEPAAS 350
+ + QS R S ++ + L +++ VA+ +E RRA ++ A++ AE
Sbjct: 1578 AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELER 1637
Query: 351 GRIICHSYLE-RLLNVEVPQKVG---SEQKEPPEEAEPVA-----AAEPEVPENNGNNSW 401
++ + L RL EV Q+ +E ++ EEAE A A E V +
Sbjct: 1638 WQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE 1697
Query: 402 PHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELD 461
++A T + AA + A+T+Q + R+ + R ++A +
Sbjct: 1698 LEKQRQLAEGTAQQRLAAEQELI----RLRAETEQGEQQRQLLEE-ELARLQREAAAATQ 1752
Query: 462 EEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIK 521
+ Q LE EL R++ ++ R+ T ++++ + A + +
Sbjct: 1753 KRQELE-AELAKVRAEMEVLLASKARAEEESRS---TSEKSKQRL---EAEAGRFRELAE 1805
Query: 522 RNTPLRMDPKEKERQRL----ENLRRKEEAEQLRRQKV----EEDKRRRLEEVKLKREE- 572
LR +E +RQR + R++ EAE++ +K+ E + + E+ LK +E
Sbjct: 1806 EAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEA 1865
Query: 573 ---RLRKVLQ----ARERVEQMKEEKKKQIEQKFAQI----DEKTEKAK----------- 610
RLR++ + R R+E+ + K IE++ AQ+ D + E+ K
Sbjct: 1866 ENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1925
Query: 611 ---EERLAEEKAKKKAAAKKME--------------EVEARRKQEEEARRLRWLQQEEEE 653
EE LA + + +KAAA K E + ++ + E EA R R L EEE
Sbjct: 1926 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1985
Query: 654 RRHQ--ELLQKK--KEEEQERLRKAA------------EAKRLAEQREQERREQ------ 691
RR + E +QK EEE R RKAA EA+RL E+ EQE Q
Sbjct: 1986 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2045
Query: 692 -----------------ERREQERREQERREQERREQERQLAEQERR----REQERLQAE 730
+++EQE ++ ++EQ +Q R AE RR E+ R+QAE
Sbjct: 2046 AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE 2105
Query: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKA 785
RE + + + + E+L++ EE+ + Q + A +L++E E++A A A +A
Sbjct: 2106 REAAQSRRQVE-EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQA 2159
Score = 94.4 bits (233), Expect = 4e-19
Identities = 75/243 (30%), Positives = 127/243 (52%), Gaps = 22/243 (9%)
Query: 539 ENLRRKEEAE---QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI 595
+ LR KE+AE +RQ E++RRR E EER++K L A E + ++ +++
Sbjct: 1961 DTLRSKEQAELEAARQRQLAAEEERRRREA-----EERVQKSLAAEEEAARQRKAALEEV 2015
Query: 596 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 655
E+ A+++E + ER +E A++ A +E +R Q EE +QQ+E+E
Sbjct: 2016 ERLKAKVEEA--RRLRERAEQESARQLQLA---QEAAQKRLQAEEKAHAFAVQQKEQEL- 2069
Query: 656 HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQ----ERREQERREQ 711
Q+ LQ+++ + +A A+R AE+ E+ R + ER + R Q ER +Q EQ
Sbjct: 2070 -QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2128
Query: 712 ERQLAEQERRREQERLQAERELQER---EKALRLQKEQLQRELEEKKKKEEQQRLAERQL 768
+ A+ + E+ R +AE+E R E+A QK+ E+E+ KK EQ + Q+
Sbjct: 2129 AQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2188
Query: 769 QEE 771
++E
Sbjct: 2189 EQE 2191
Score = 93.6 bits (231), Expect = 8e-19
Identities = 87/327 (26%), Positives = 161/327 (49%), Gaps = 29/327 (8%)
Query: 531 KEKERQRLENLRRKEEA--EQLRRQKVEEDKRRRL---EEVKLKREERLRKVLQARERVE 585
+ KE+ LE R+++ A E+ RR++ EE ++ L EE +R+ L +V + + +VE
Sbjct: 1964 RSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE 2023
Query: 586 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE------ 639
+ + +++ ++ Q+ E A++ AEEKA A +K +E++ +QE+
Sbjct: 2024 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2083
Query: 640 --EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 697
EA R +E EE R +Q ++E Q R R+ EA+RL +Q +E+ + + Q
Sbjct: 2084 RGEAEAARRAAEEAEEAR----VQAEREAAQSR-RQVEEAERL-KQSAEEQAQARAQAQA 2137
Query: 698 RREQERREQERREQERQLAEQERRREQERLQAERELQER--EKALRLQKEQLQRELEEKK 755
E+ R+E E+ R AEQ R+++ AE E ++ E+ LR QK Q+++EL +
Sbjct: 2138 AAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR-QKAQVEQELTTLR 2196
Query: 756 KKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKINP 815
+ E+ + L EE ++ EA A++ + V+ + + + +I
Sbjct: 2197 LQLEETDHQKNLLDEELQRLKAEATEAARQRS---QVEEELFSVRVQMEELSKLKARIEA 2253
Query: 816 DNYGMDLNSDDST----DDEAHPRKPI 838
+N + L D+T +EA K +
Sbjct: 2254 ENRALILRDKDNTQRFLQEEAEKMKQV 2280
Score = 89.0 bits (219), Expect = 2e-17
Identities = 77/277 (27%), Positives = 135/277 (48%), Gaps = 18/277 (6%)
Query: 513 RSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE 572
R + ++ + + KE +++ E + R+EEA ++ KR EE++ R+
Sbjct: 1377 RQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV----DAQQQKRSIQEELQQLRQS 1432
Query: 573 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 632
++ QA+ R + E + +IE++ + + E + +R E + +A + EE E
Sbjct: 1433 SEAEI-QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAE-GELQALRARAEEAE 1490
Query: 633 A--RRKQEEEARRLRWLQQEEEERRHQ---ELLQKKKEE-----EQERLRKAAEAKRLAE 682
A R+ Q EEA RLR Q+E +R+ Q EL + K E E++R +A E RL
Sbjct: 1491 AQKRQAQ-EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQA 1549
Query: 683 QREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRL 742
+ + R Q E+ R+ Q E +R E +L + ++ Q ER LQE A+
Sbjct: 1550 EEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ 1609
Query: 743 QKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 779
+E+ +R +++ + E + AER+L E + KA EA
Sbjct: 1610 LREEAERRAQQQAEAERAREEAEREL-ERWQLKANEA 1645
Score = 87.4 bits (215), Expect = 5e-17
Identities = 138/560 (24%), Positives = 235/560 (41%), Gaps = 117/560 (20%)
Query: 316 QVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQ 375
Q L Q+ S++ + A+RR A++ E + R S R E + S +
Sbjct: 2071 QTLQQEQSVLDQLRGEAE-AARRAAEEAEEARVQAEREAAQS---RRQVEEAERLKQSAE 2126
Query: 376 KEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTD 435
++ A+ AAAE E + E A + A + A ++ K
Sbjct: 2127 EQAQARAQAQAAAEKLRKEA---------EQEAARRAQAEQAALRQKQAADAEMEKHKKF 2177
Query: 436 QADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTF 495
R+ Q + + + + E D +++L DEELQ +++ + S+V L +
Sbjct: 2178 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2237
Query: 496 LHTVQRNQMLMTPTSAPRSVMKSFIKRNTP-LRMDPKEKERQRLENLRR----KEEAEQL 550
++ L A + K NT + EK +Q E R +EA +L
Sbjct: 2238 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2297
Query: 551 RRQKVEED--KRRRLEEVKLKREERLRKVLQAR------ERVEQMKE----------EKK 592
R Q EED ++R L E LK E+++ V +A E ++Q KE E K
Sbjct: 2298 R-QLAEEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK 2354
Query: 593 KQIEQKFAQIDE---KTEKAKEERLAEEKAKKKAAAKKMEEVE-ARRKQEEEARRLRWLQ 648
+Q+ Q+ A+ + +T +A+ +R E A+ + ++ E+ A+ + EE+A+R R
Sbjct: 2355 EQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQA 2414
Query: 649 QEEEERRHQ---------------ELLQKKKEEEQERLRKA-AEAKRLAEQREQERR--- 689
+E E+ H+ E+ +++ + + ERLR+A AE +R E+ +QE +
Sbjct: 2415 EEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2474
Query: 690 ---------------------------------------EQERREQER-------REQER 703
EQE+ + E+ + Q+
Sbjct: 2475 LKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL 2534
Query: 704 REQERREQERQLAEQERRR------EQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
RE+++R+Q++ EQER+R E R Q E E R K LQ+ + QR +E+
Sbjct: 2535 REEQQRQQQQM--EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLA 2592
Query: 758 EEQQRLAER-QLQEEQEKKA 776
EE QRL E+ QL EEQ + A
Sbjct: 2593 EENQRLREQLQLLEEQHRAA 2612
Score = 86.7 bits (213), Expect = 9e-17
Identities = 98/403 (24%), Positives = 185/403 (45%), Gaps = 53/403 (13%)
Query: 445 QSARRKRSYKQAVSELDEEQHLED--------EELQPPRSKTPSSPCPASKVVRPLRTFL 496
Q ARR++ QA+ D + E EE++ K A + + ++ +
Sbjct: 1228 QDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYE 1287
Query: 497 HTVQRNQMLMTPTSAP------RSVMKSFIKRNTPLRMDPKEKERQRL-------ENLRR 543
+ + + P ++P +S +S I+ LR E E LRR
Sbjct: 1288 LQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRR 1347
Query: 544 KEEAEQLRRQKVEEDKRRRLE-EVKLKREERLRKV-LQARERVEQMKEEKKKQIEQKFAQ 601
EE E+L Q+ E++ R E E L+++ +L + QA+ + E+ +E +++++++ +
Sbjct: 1348 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1407
Query: 602 IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQ 661
+E A++++ + ++ ++ E++A+ +Q E A R R L+ EEE R +
Sbjct: 1408 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR-LRIEEEIR-----VV 1461
Query: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 721
+ + E ER R AE E + R +E Q+R+ QE E+ RR Q+ ++ +R
Sbjct: 1462 RLQLEATERQRGGAEG----ELQALRARAEEAEAQKRQAQEEAERLRR----QVQDESQR 1513
Query: 722 REQ------ERLQAERE-LQEREKA------LRLQKEQLQREL---EEKKKKEEQQRLAE 765
+ Q R++AE E +E+++A LRLQ E+ +R L E ++ ++ Q L
Sbjct: 1514 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALET 1573
Query: 766 RQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHR 808
Q E E ++K A+ A K + +Q Q+ + R
Sbjct: 1574 AQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER 1616
Score = 86.7 bits (213), Expect = 9e-17
Identities = 120/544 (22%), Positives = 218/544 (40%), Gaps = 79/544 (14%)
Query: 299 DSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSY 358
+SQ R + + +S +V A+ + KQ ++ RL + AE R + +
Sbjct: 1510 ESQRKRQAEVELAS---RVKAEAEAAREKQRALQALEELRLQAEEAE------RRLRQAE 1560
Query: 359 LERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPA 418
+ER V+V + E +++ + AE S +A +
Sbjct: 1561 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER---SLQEEHVAVAQLREEAERR 1617
Query: 419 ASSPETPSAGQQEA---------KTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDE 469
A ++EA K ++A R + +++S QA +E +E E E
Sbjct: 1618 AQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKE---EAE 1674
Query: 470 ELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMD 529
R K + VR +++ + L T+ R + + R LR +
Sbjct: 1675 REARRRGKAEE------QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR---LRAE 1725
Query: 530 PKEKERQR------LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER 583
++ E+QR L L+R+ A +RQ++E + L +V+ + E L +A E
Sbjct: 1726 TEQGEQQRQLLEEELARLQREAAAATQKRQELEAE----LAKVRAEMEVLLASKARAEEE 1781
Query: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE--- 640
E+ K+++E + + E E+A R E+AK++ + EE AR++ E E
Sbjct: 1782 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQR--QLAEEDAARQRAEAERVL 1839
Query: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
A +L + + + E+ K+KE E ERLR+ AE + +R +E+ Q + + E R
Sbjct: 1840 AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL 1899
Query: 701 QERREQERREQERQLA------EQERRREQE-------------------------RLQA 729
+ R+ E ERQ Q R+ E+E R A
Sbjct: 1900 AQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA 1959
Query: 730 ERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVT 789
E L+ +E+A Q Q EE++++ E + ++ L E+E + A + +
Sbjct: 1960 EDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLK 2019
Query: 790 VDVQ 793
V+
Sbjct: 2020 AKVE 2023
Score = 82.8 bits (203), Expect = 1e-15
Identities = 119/525 (22%), Positives = 224/525 (42%), Gaps = 92/525 (17%)
Query: 319 AQKYSLVAKQESVVRRASRRLAKK-TAEEPAASGRIICHSYLERLL-------------- 363
A++ L A++E R A R+ K AEE AA R +ERL
Sbjct: 1974 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2033
Query: 364 -----NVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPA 418
+++ Q+ ++ + E+A A + E + + + + A
Sbjct: 2034 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE---QELQQTLQQEQSVLDQLRGEAEAA 2090
Query: 419 ASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKT 478
+ E + +A+ + A R+ ++ R K+S ++ + Q ++ + +
Sbjct: 2091 RRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2150
Query: 479 PSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRL 538
+R + +++++ T ++ ++ + T LR+ +E + Q+
Sbjct: 2151 ARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQEL---TTLRLQLEETDHQKN 2207
Query: 539 ---ENLRR-KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 594
E L+R K EA + RQ+ + ++ V+++ +L+ ++A R +++ K
Sbjct: 2208 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD---KD 2264
Query: 595 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 654
Q+F Q E+ EK K+ +AEE A+ AA +EA RLR L +E+ +
Sbjct: 2265 NTQRFLQ--EEAEKMKQ--VAEEAARLSVAA-------------QEAARLRQLAEEDLAQ 2307
Query: 655 RH---QELLQKKKEEEQERLRKAAEAKRLAEQR----EQERREQERREQERRE------- 700
+ +++L++K + QE R AEA+ L +Q+ EQ RR QE +EQ ++
Sbjct: 2308 QRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2367
Query: 701 -QERREQERREQERQLAEQER-------------RREQE----RLQAER--------ELQ 734
Q E ER+ Q AE ER R E++ R QAE EL
Sbjct: 2368 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2427
Query: 735 EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 779
+EK +Q ++QR+ + + ++ +AE L+ E+EK +EA
Sbjct: 2428 TQEKVTLVQTLEIQRQQSDHDAERLREAIAE--LEREKEKLQQEA 2470
Score = 75.1 bits (183), Expect = 3e-13
Identities = 70/275 (25%), Positives = 129/275 (46%), Gaps = 16/275 (5%)
Query: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL--KREERLRKVLQARERVEQMKE 589
E ERQR + + E +LR ++ + R E+ + K+ E + + L E Q K
Sbjct: 2373 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKV 2432
Query: 590 EKKKQIEQKFAQIDEKTEKAKEE--RLAEEKAKKKAAAK--KMEEVEARRKQEEEARRLR 645
+ +E + Q D E+ +E L EK K + AK +++ E + Q+E+ +
Sbjct: 2433 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQET 2492
Query: 646 WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR- 704
Q+ LLQ+++ EQE+ + + + +Q R EQ+R++Q+ ++ +R
Sbjct: 2493 QALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRL 2552
Query: 705 ---EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 761
+E R ++ + E RR+++E Q E++ +++E+ L E+ QR E+ + EEQ
Sbjct: 2553 VASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL---AEENQRLREQLQLLEEQH 2609
Query: 762 RLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPA 796
R A L +E A + A N + PA
Sbjct: 2610 RAA---LAHSEEVTASQVAATKTLPNGRDALDGPA 2641
Score = 65.5 bits (158), Expect = 2e-10
Identities = 80/345 (23%), Positives = 153/345 (44%), Gaps = 46/345 (13%)
Query: 433 KTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPL 492
+T +A+ R+ SA +R K V+E+ Q +E+ Q R + A ++ L
Sbjct: 2370 RTLEAERQRQLEMSAEAER-LKLRVAEMSRAQARAEEDAQRFRKQ-------AEEIGEKL 2421
Query: 493 -RTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLR 551
RT L T ++ ++ T ++ + + +RL + E E+ +
Sbjct: 2422 HRTELATQEKVTLVQT----------------LEIQRQQSDHDAERLREAIAELEREKEK 2465
Query: 552 RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 611
Q+ + + + EE++ ++E+L LQ + ++Q +K + Q+ I++ EKAK
Sbjct: 2466 LQQEAKLLQLKSEEMQTVQQEQL---LQETQALQQSFLSEKDSLLQRERFIEQ--EKAKL 2520
Query: 612 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERL 671
E+L +++ K A+++ E + R++Q+ E R R + EE RR Q ++ +QE L
Sbjct: 2521 EQLFQDEVAK---AQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL 2577
Query: 672 RKAAEAKRLAEQREQERREQERREQERREQERRE-QERREQERQLAEQERRREQERLQAE 730
+Q EQ+RR+QE E ++ R + Q EQ R ++ A
Sbjct: 2578 ----------QQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAAT 2627
Query: 731 RELQEREKAL--RLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE 773
+ L AL + + + + ++K QRL E + +E
Sbjct: 2628 KTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEE 2672
Score = 47.4 bits (111), Expect = 6e-05
Identities = 61/278 (21%), Positives = 128/278 (46%), Gaps = 35/278 (12%)
Query: 541 LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR---KVLQARERVEQMKEEKKKQIEQ 597
+R + AE++ R E+ K + L E + K L+A+ +Q + + +
Sbjct: 1099 IRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELR 1158
Query: 598 KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA--------RRKQEEEARRLRWLQQ 649
++ E+ ++ ER E + ++ A+ +E +A +R+ E+ R+LR+ +
Sbjct: 1159 GAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYR- 1217
Query: 650 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR--EQERREQERREQERREQE 707
E + L ++ +EQ + A+++ + EQ QE+ E+ R E+ E+ +R +
Sbjct: 1218 ESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAK 1277
Query: 708 R-----REQERQLAEQERRRE-------QERLQ--AERELQE-------REKALRLQKEQ 746
+ ++ E QL + + E + ++Q +E +QE + L +
Sbjct: 1278 QYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQY 1337
Query: 747 LQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 784
++ E ++ EE++RLAE+Q EE+E+ A+ A K
Sbjct: 1338 IKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEK 1375
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 102 bits (253), Expect = 2e-21
Identities = 100/387 (25%), Positives = 182/387 (47%), Gaps = 34/387 (8%)
Query: 418 AASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSK 477
A + + + ++EAK Q R + RR+ + AV +++ +++E Q +S
Sbjct: 1376 AEAHAQAKAQAEREAKELQQ---RMQEEVVRREEA---AVDAQQQKRSIQEELQQLRQSS 1429
Query: 478 TPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQR 537
A + R+ L + +++ A LR +E E Q+
Sbjct: 1430 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1489
Query: 538 LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERL--------RKVLQARERVEQMKE 589
+ +EEAE+LRRQ +E +R+R EV+L + ++ LQA E + E
Sbjct: 1490 RQ---AQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1546
Query: 590 EKKKQIEQ----KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 645
E ++++ Q + Q+ E A+ AE ++K+ + A+K ++E R +EE +
Sbjct: 1547 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE--RSLQEEHVAVA 1604
Query: 646 WLQQEEEERRHQELLQKKKEEEQER-----LRKAAEAKRL---AEQREQERREQERREQE 697
L++E E R Q+ ++ EE ER KA EA RL AE+ Q++ + ++
Sbjct: 1605 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1664
Query: 698 RREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
++E+ RE RR + + A ++R ++ L+ +R+L E RL EQ L + ++
Sbjct: 1665 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQ 1724
Query: 758 EEQQRLAERQLQEEQEKKAKEAAGASK 784
EQQR + L+EE + +EAA A++
Sbjct: 1725 GEQQR---QLLEEELARLQREAAAATQ 1748
Score = 96.7 bits (239), Expect = 9e-20
Identities = 150/595 (25%), Positives = 258/595 (43%), Gaps = 118/595 (19%)
Query: 296 SRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAK-QESVVRRASRRL----AKKTAEEPAAS 350
+ + QS R S ++ + L +++ VA+ +E RRA ++ A++ AE
Sbjct: 1574 AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELER 1633
Query: 351 GRIICHSYLE-RLLNVEVPQKVG---SEQKEPPEEAEPVA-----AAEPEVPENNGNNSW 401
++ + L RL EV Q+ +E ++ EEAE A A E V +
Sbjct: 1634 WQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE 1693
Query: 402 PHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELD 461
++A T + AA + A+T+Q + R+ + R ++A +
Sbjct: 1694 LEKQRQLAEGTAQQRLAAEQELI----RLRAETEQGEQQRQLLEE-ELARLQREAAAATQ 1748
Query: 462 EEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIK 521
+ Q LE EL R++ ++ R+ T ++++ + A + +
Sbjct: 1749 KRQELE-AELAKVRAEMEVLLASKARAEEESRS---TSEKSKQRL---EAEAGRFRELAE 1801
Query: 522 RNTPLRMDPKEKERQRL----ENLRRKEEAEQLRRQKV----EEDKRRRLEEVKLKREE- 572
LR +E +RQR + R++ EAE++ +K+ E + + E+ LK +E
Sbjct: 1802 EAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEA 1861
Query: 573 ---RLRKVLQ----ARERVEQMKEEKKKQIEQKFAQI----DEKTEKAK----------- 610
RLR++ + R R+E+ + K IE++ AQ+ D + E+ K
Sbjct: 1862 ENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1921
Query: 611 ---EERLAEEKAKKKAAAKKME--------------EVEARRKQEEEARRLRWLQQEEEE 653
EE LA + + +KAAA K E + ++ + E EA R R L EEE
Sbjct: 1922 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1981
Query: 654 RRHQ--ELLQKK--KEEEQERLRKAA------------EAKRLAEQREQERREQ------ 691
RR + E +QK EEE R RKAA EA+RL E+ EQE Q
Sbjct: 1982 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2041
Query: 692 -----------------ERREQERREQERREQERREQERQLAEQERR----REQERLQAE 730
+++EQE ++ ++EQ +Q R AE RR E+ R+QAE
Sbjct: 2042 AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE 2101
Query: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKA 785
RE + + + + E+L++ EE+ + Q + A +L++E E++A A A +A
Sbjct: 2102 REAAQSRRQVE-EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQA 2155
Score = 94.4 bits (233), Expect = 4e-19
Identities = 75/243 (30%), Positives = 127/243 (52%), Gaps = 22/243 (9%)
Query: 539 ENLRRKEEAE---QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI 595
+ LR KE+AE +RQ E++RRR E EER++K L A E + ++ +++
Sbjct: 1957 DTLRSKEQAELEAARQRQLAAEEERRRREA-----EERVQKSLAAEEEAARQRKAALEEV 2011
Query: 596 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 655
E+ A+++E + ER +E A++ A +E +R Q EE +QQ+E+E
Sbjct: 2012 ERLKAKVEEA--RRLRERAEQESARQLQLA---QEAAQKRLQAEEKAHAFAVQQKEQEL- 2065
Query: 656 HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQ----ERREQERREQ 711
Q+ LQ+++ + +A A+R AE+ E+ R + ER + R Q ER +Q EQ
Sbjct: 2066 -QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2124
Query: 712 ERQLAEQERRREQERLQAERELQER---EKALRLQKEQLQRELEEKKKKEEQQRLAERQL 768
+ A+ + E+ R +AE+E R E+A QK+ E+E+ KK EQ + Q+
Sbjct: 2125 AQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2184
Query: 769 QEE 771
++E
Sbjct: 2185 EQE 2187
Score = 93.6 bits (231), Expect = 8e-19
Identities = 87/327 (26%), Positives = 161/327 (49%), Gaps = 29/327 (8%)
Query: 531 KEKERQRLENLRRKEEA--EQLRRQKVEEDKRRRL---EEVKLKREERLRKVLQARERVE 585
+ KE+ LE R+++ A E+ RR++ EE ++ L EE +R+ L +V + + +VE
Sbjct: 1960 RSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE 2019
Query: 586 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE------ 639
+ + +++ ++ Q+ E A++ AEEKA A +K +E++ +QE+
Sbjct: 2020 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2079
Query: 640 --EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 697
EA R +E EE R +Q ++E Q R R+ EA+RL +Q +E+ + + Q
Sbjct: 2080 RGEAEAARRAAEEAEEAR----VQAEREAAQSR-RQVEEAERL-KQSAEEQAQARAQAQA 2133
Query: 698 RREQERREQERREQERQLAEQERRREQERLQAERELQER--EKALRLQKEQLQRELEEKK 755
E+ R+E E+ R AEQ R+++ AE E ++ E+ LR QK Q+++EL +
Sbjct: 2134 AAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR-QKAQVEQELTTLR 2192
Query: 756 KKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKINP 815
+ E+ + L EE ++ EA A++ + V+ + + + +I
Sbjct: 2193 LQLEETDHQKNLLDEELQRLKAEATEAARQRS---QVEEELFSVRVQMEELSKLKARIEA 2249
Query: 816 DNYGMDLNSDDST----DDEAHPRKPI 838
+N + L D+T +EA K +
Sbjct: 2250 ENRALILRDKDNTQRFLQEEAEKMKQV 2276
Score = 89.0 bits (219), Expect = 2e-17
Identities = 77/277 (27%), Positives = 135/277 (48%), Gaps = 18/277 (6%)
Query: 513 RSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE 572
R + ++ + + KE +++ E + R+EEA ++ KR EE++ R+
Sbjct: 1373 RQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV----DAQQQKRSIQEELQQLRQS 1428
Query: 573 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 632
++ QA+ R + E + +IE++ + + E + +R E + +A + EE E
Sbjct: 1429 SEAEI-QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAE-GELQALRARAEEAE 1486
Query: 633 A--RRKQEEEARRLRWLQQEEEERRHQ---ELLQKKKEE-----EQERLRKAAEAKRLAE 682
A R+ Q EEA RLR Q+E +R+ Q EL + K E E++R +A E RL
Sbjct: 1487 AQKRQAQ-EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQA 1545
Query: 683 QREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRL 742
+ + R Q E+ R+ Q E +R E +L + ++ Q ER LQE A+
Sbjct: 1546 EEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ 1605
Query: 743 QKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 779
+E+ +R +++ + E + AER+L E + KA EA
Sbjct: 1606 LREEAERRAQQQAEAERAREEAEREL-ERWQLKANEA 1641
Score = 87.4 bits (215), Expect = 5e-17
Identities = 138/560 (24%), Positives = 235/560 (41%), Gaps = 117/560 (20%)
Query: 316 QVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQ 375
Q L Q+ S++ + A+RR A++ E + R S R E + S +
Sbjct: 2067 QTLQQEQSVLDQLRGEAE-AARRAAEEAEEARVQAEREAAQS---RRQVEEAERLKQSAE 2122
Query: 376 KEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTD 435
++ A+ AAAE E + E A + A + A ++ K
Sbjct: 2123 EQAQARAQAQAAAEKLRKEA---------EQEAARRAQAEQAALRQKQAADAEMEKHKKF 2173
Query: 436 QADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTF 495
R+ Q + + + + E D +++L DEELQ +++ + S+V L +
Sbjct: 2174 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2233
Query: 496 LHTVQRNQMLMTPTSAPRSVMKSFIKRNTP-LRMDPKEKERQRLENLRR----KEEAEQL 550
++ L A + K NT + EK +Q E R +EA +L
Sbjct: 2234 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2293
Query: 551 RRQKVEED--KRRRLEEVKLKREERLRKVLQAR------ERVEQMKE----------EKK 592
R Q EED ++R L E LK E+++ V +A E ++Q KE E K
Sbjct: 2294 R-QLAEEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK 2350
Query: 593 KQIEQKFAQIDE---KTEKAKEERLAEEKAKKKAAAKKMEEVE-ARRKQEEEARRLRWLQ 648
+Q+ Q+ A+ + +T +A+ +R E A+ + ++ E+ A+ + EE+A+R R
Sbjct: 2351 EQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQA 2410
Query: 649 QEEEERRHQ---------------ELLQKKKEEEQERLRKA-AEAKRLAEQREQERR--- 689
+E E+ H+ E+ +++ + + ERLR+A AE +R E+ +QE +
Sbjct: 2411 EEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2470
Query: 690 ---------------------------------------EQERREQER-------REQER 703
EQE+ + E+ + Q+
Sbjct: 2471 LKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL 2530
Query: 704 REQERREQERQLAEQERRR------EQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
RE+++R+Q++ EQER+R E R Q E E R K LQ+ + QR +E+
Sbjct: 2531 REEQQRQQQQM--EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLA 2588
Query: 758 EEQQRLAER-QLQEEQEKKA 776
EE QRL E+ QL EEQ + A
Sbjct: 2589 EENQRLREQLQLLEEQHRAA 2608
Score = 86.7 bits (213), Expect = 9e-17
Identities = 98/403 (24%), Positives = 185/403 (45%), Gaps = 53/403 (13%)
Query: 445 QSARRKRSYKQAVSELDEEQHLED--------EELQPPRSKTPSSPCPASKVVRPLRTFL 496
Q ARR++ QA+ D + E EE++ K A + + ++ +
Sbjct: 1224 QDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYE 1283
Query: 497 HTVQRNQMLMTPTSAP------RSVMKSFIKRNTPLRMDPKEKERQRL-------ENLRR 543
+ + + P ++P +S +S I+ LR E E LRR
Sbjct: 1284 LQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRR 1343
Query: 544 KEEAEQLRRQKVEEDKRRRLE-EVKLKREERLRKV-LQARERVEQMKEEKKKQIEQKFAQ 601
EE E+L Q+ E++ R E E L+++ +L + QA+ + E+ +E +++++++ +
Sbjct: 1344 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1403
Query: 602 IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQ 661
+E A++++ + ++ ++ E++A+ +Q E A R R L+ EEE R +
Sbjct: 1404 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR-LRIEEEIR-----VV 1457
Query: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 721
+ + E ER R AE E + R +E Q+R+ QE E+ RR Q+ ++ +R
Sbjct: 1458 RLQLEATERQRGGAEG----ELQALRARAEEAEAQKRQAQEEAERLRR----QVQDESQR 1509
Query: 722 REQ------ERLQAERE-LQEREKA------LRLQKEQLQREL---EEKKKKEEQQRLAE 765
+ Q R++AE E +E+++A LRLQ E+ +R L E ++ ++ Q L
Sbjct: 1510 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALET 1569
Query: 766 RQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHR 808
Q E E ++K A+ A K + +Q Q+ + R
Sbjct: 1570 AQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER 1612
Score = 86.7 bits (213), Expect = 9e-17
Identities = 120/544 (22%), Positives = 218/544 (40%), Gaps = 79/544 (14%)
Query: 299 DSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSY 358
+SQ R + + +S +V A+ + KQ ++ RL + AE R + +
Sbjct: 1506 ESQRKRQAEVELAS---RVKAEAEAAREKQRALQALEELRLQAEEAE------RRLRQAE 1556
Query: 359 LERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPA 418
+ER V+V + E +++ + AE S +A +
Sbjct: 1557 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER---SLQEEHVAVAQLREEAERR 1613
Query: 419 ASSPETPSAGQQEA---------KTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDE 469
A ++EA K ++A R + +++S QA +E +E E E
Sbjct: 1614 AQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKE---EAE 1670
Query: 470 ELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMD 529
R K + VR +++ + L T+ R + + R LR +
Sbjct: 1671 REARRRGKAEE------QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR---LRAE 1721
Query: 530 PKEKERQR------LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER 583
++ E+QR L L+R+ A +RQ++E + L +V+ + E L +A E
Sbjct: 1722 TEQGEQQRQLLEEELARLQREAAAATQKRQELEAE----LAKVRAEMEVLLASKARAEEE 1777
Query: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE--- 640
E+ K+++E + + E E+A R E+AK++ + EE AR++ E E
Sbjct: 1778 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQR--QLAEEDAARQRAEAERVL 1835
Query: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
A +L + + + E+ K+KE E ERLR+ AE + +R +E+ Q + + E R
Sbjct: 1836 AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL 1895
Query: 701 QERREQERREQERQLA------EQERRREQE-------------------------RLQA 729
+ R+ E ERQ Q R+ E+E R A
Sbjct: 1896 AQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA 1955
Query: 730 ERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVT 789
E L+ +E+A Q Q EE++++ E + ++ L E+E + A + +
Sbjct: 1956 EDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLK 2015
Query: 790 VDVQ 793
V+
Sbjct: 2016 AKVE 2019
Score = 82.8 bits (203), Expect = 1e-15
Identities = 119/525 (22%), Positives = 224/525 (42%), Gaps = 92/525 (17%)
Query: 319 AQKYSLVAKQESVVRRASRRLAKK-TAEEPAASGRIICHSYLERLL-------------- 363
A++ L A++E R A R+ K AEE AA R +ERL
Sbjct: 1970 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2029
Query: 364 -----NVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPA 418
+++ Q+ ++ + E+A A + E + + + + A
Sbjct: 2030 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE---QELQQTLQQEQSVLDQLRGEAEAA 2086
Query: 419 ASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKT 478
+ E + +A+ + A R+ ++ R K+S ++ + Q ++ + +
Sbjct: 2087 RRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2146
Query: 479 PSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRL 538
+R + +++++ T ++ ++ + T LR+ +E + Q+
Sbjct: 2147 ARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQEL---TTLRLQLEETDHQKN 2203
Query: 539 ---ENLRR-KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 594
E L+R K EA + RQ+ + ++ V+++ +L+ ++A R +++ K
Sbjct: 2204 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD---KD 2260
Query: 595 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 654
Q+F Q E+ EK K+ +AEE A+ AA +EA RLR L +E+ +
Sbjct: 2261 NTQRFLQ--EEAEKMKQ--VAEEAARLSVAA-------------QEAARLRQLAEEDLAQ 2303
Query: 655 RH---QELLQKKKEEEQERLRKAAEAKRLAEQR----EQERREQERREQERRE------- 700
+ +++L++K + QE R AEA+ L +Q+ EQ RR QE +EQ ++
Sbjct: 2304 QRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2363
Query: 701 -QERREQERREQERQLAEQER-------------RREQE----RLQAER--------ELQ 734
Q E ER+ Q AE ER R E++ R QAE EL
Sbjct: 2364 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2423
Query: 735 EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 779
+EK +Q ++QR+ + + ++ +AE L+ E+EK +EA
Sbjct: 2424 TQEKVTLVQTLEIQRQQSDHDAERLREAIAE--LEREKEKLQQEA 2466
Score = 75.1 bits (183), Expect = 3e-13
Identities = 70/275 (25%), Positives = 129/275 (46%), Gaps = 16/275 (5%)
Query: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL--KREERLRKVLQARERVEQMKE 589
E ERQR + + E +LR ++ + R E+ + K+ E + + L E Q K
Sbjct: 2369 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKV 2428
Query: 590 EKKKQIEQKFAQIDEKTEKAKEE--RLAEEKAKKKAAAK--KMEEVEARRKQEEEARRLR 645
+ +E + Q D E+ +E L EK K + AK +++ E + Q+E+ +
Sbjct: 2429 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQET 2488
Query: 646 WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR- 704
Q+ LLQ+++ EQE+ + + + +Q R EQ+R++Q+ ++ +R
Sbjct: 2489 QALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRL 2548
Query: 705 ---EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 761
+E R ++ + E RR+++E Q E++ +++E+ L E+ QR E+ + EEQ
Sbjct: 2549 VASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL---AEENQRLREQLQLLEEQH 2605
Query: 762 RLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPA 796
R A L +E A + A N + PA
Sbjct: 2606 RAA---LAHSEEVTASQVAATKTLPNGRDALDGPA 2637
Score = 65.5 bits (158), Expect = 2e-10
Identities = 80/345 (23%), Positives = 153/345 (44%), Gaps = 46/345 (13%)
Query: 433 KTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPL 492
+T +A+ R+ SA +R K V+E+ Q +E+ Q R + A ++ L
Sbjct: 2366 RTLEAERQRQLEMSAEAER-LKLRVAEMSRAQARAEEDAQRFRKQ-------AEEIGEKL 2417
Query: 493 -RTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLR 551
RT L T ++ ++ T ++ + + +RL + E E+ +
Sbjct: 2418 HRTELATQEKVTLVQT----------------LEIQRQQSDHDAERLREAIAELEREKEK 2461
Query: 552 RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 611
Q+ + + + EE++ ++E+L LQ + ++Q +K + Q+ I++ EKAK
Sbjct: 2462 LQQEAKLLQLKSEEMQTVQQEQL---LQETQALQQSFLSEKDSLLQRERFIEQ--EKAKL 2516
Query: 612 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERL 671
E+L +++ K A+++ E + R++Q+ E R R + EE RR Q ++ +QE L
Sbjct: 2517 EQLFQDEVAK---AQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL 2573
Query: 672 RKAAEAKRLAEQREQERREQERREQERREQERRE-QERREQERQLAEQERRREQERLQAE 730
+Q EQ+RR+QE E ++ R + Q EQ R ++ A
Sbjct: 2574 ----------QQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAAT 2623
Query: 731 RELQEREKAL--RLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE 773
+ L AL + + + + ++K QRL E + +E
Sbjct: 2624 KTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEE 2668
Score = 47.4 bits (111), Expect = 6e-05
Identities = 61/278 (21%), Positives = 128/278 (46%), Gaps = 35/278 (12%)
Query: 541 LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR---KVLQARERVEQMKEEKKKQIEQ 597
+R + AE++ R E+ K + L E + K L+A+ +Q + + +
Sbjct: 1095 IRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELR 1154
Query: 598 KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA--------RRKQEEEARRLRWLQQ 649
++ E+ ++ ER E + ++ A+ +E +A +R+ E+ R+LR+ +
Sbjct: 1155 GAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYR- 1213
Query: 650 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR--EQERREQERREQERREQE 707
E + L ++ +EQ + A+++ + EQ QE+ E+ R E+ E+ +R +
Sbjct: 1214 ESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAK 1273
Query: 708 R-----REQERQLAEQERRRE-------QERLQ--AERELQE-------REKALRLQKEQ 746
+ ++ E QL + + E + ++Q +E +QE + L +
Sbjct: 1274 QYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQY 1333
Query: 747 LQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 784
++ E ++ EE++RLAE+Q EE+E+ A+ A K
Sbjct: 1334 IKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEK 1371
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 102 bits (253), Expect = 2e-21
Identities = 100/387 (25%), Positives = 182/387 (47%), Gaps = 34/387 (8%)
Query: 418 AASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSK 477
A + + + ++EAK Q R + RR+ + AV +++ +++E Q +S
Sbjct: 1344 AEAHAQAKAQAEREAKELQQ---RMQEEVVRREEA---AVDAQQQKRSIQEELQQLRQSS 1397
Query: 478 TPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQR 537
A + R+ L + +++ A LR +E E Q+
Sbjct: 1398 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1457
Query: 538 LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERL--------RKVLQARERVEQMKE 589
+ +EEAE+LRRQ +E +R+R EV+L + ++ LQA E + E
Sbjct: 1458 RQ---AQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1514
Query: 590 EKKKQIEQ----KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 645
E ++++ Q + Q+ E A+ AE ++K+ + A+K ++E R +EE +
Sbjct: 1515 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE--RSLQEEHVAVA 1572
Query: 646 WLQQEEEERRHQELLQKKKEEEQER-----LRKAAEAKRL---AEQREQERREQERREQE 697
L++E E R Q+ ++ EE ER KA EA RL AE+ Q++ + ++
Sbjct: 1573 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1632
Query: 698 RREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
++E+ RE RR + + A ++R ++ L+ +R+L E RL EQ L + ++
Sbjct: 1633 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQ 1692
Query: 758 EEQQRLAERQLQEEQEKKAKEAAGASK 784
EQQR + L+EE + +EAA A++
Sbjct: 1693 GEQQR---QLLEEELARLQREAAAATQ 1716
Score = 96.7 bits (239), Expect = 9e-20
Identities = 150/595 (25%), Positives = 258/595 (43%), Gaps = 118/595 (19%)
Query: 296 SRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAK-QESVVRRASRRL----AKKTAEEPAAS 350
+ + QS R S ++ + L +++ VA+ +E RRA ++ A++ AE
Sbjct: 1542 AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELER 1601
Query: 351 GRIICHSYLE-RLLNVEVPQKVG---SEQKEPPEEAEPVA-----AAEPEVPENNGNNSW 401
++ + L RL EV Q+ +E ++ EEAE A A E V +
Sbjct: 1602 WQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE 1661
Query: 402 PHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELD 461
++A T + AA + A+T+Q + R+ + R ++A +
Sbjct: 1662 LEKQRQLAEGTAQQRLAAEQELI----RLRAETEQGEQQRQLLEE-ELARLQREAAAATQ 1716
Query: 462 EEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIK 521
+ Q LE EL R++ ++ R+ T ++++ + A + +
Sbjct: 1717 KRQELE-AELAKVRAEMEVLLASKARAEEESRS---TSEKSKQRL---EAEAGRFRELAE 1769
Query: 522 RNTPLRMDPKEKERQRL----ENLRRKEEAEQLRRQKV----EEDKRRRLEEVKLKREE- 572
LR +E +RQR + R++ EAE++ +K+ E + + E+ LK +E
Sbjct: 1770 EAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEA 1829
Query: 573 ---RLRKVLQ----ARERVEQMKEEKKKQIEQKFAQI----DEKTEKAK----------- 610
RLR++ + R R+E+ + K IE++ AQ+ D + E+ K
Sbjct: 1830 ENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1889
Query: 611 ---EERLAEEKAKKKAAAKKME--------------EVEARRKQEEEARRLRWLQQEEEE 653
EE LA + + +KAAA K E + ++ + E EA R R L EEE
Sbjct: 1890 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1949
Query: 654 RRHQ--ELLQKK--KEEEQERLRKAA------------EAKRLAEQREQERREQ------ 691
RR + E +QK EEE R RKAA EA+RL E+ EQE Q
Sbjct: 1950 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2009
Query: 692 -----------------ERREQERREQERREQERREQERQLAEQERR----REQERLQAE 730
+++EQE ++ ++EQ +Q R AE RR E+ R+QAE
Sbjct: 2010 AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE 2069
Query: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKA 785
RE + + + + E+L++ EE+ + Q + A +L++E E++A A A +A
Sbjct: 2070 REAAQSRRQVE-EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQA 2123
Score = 94.4 bits (233), Expect = 4e-19
Identities = 75/243 (30%), Positives = 127/243 (52%), Gaps = 22/243 (9%)
Query: 539 ENLRRKEEAE---QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI 595
+ LR KE+AE +RQ E++RRR E EER++K L A E + ++ +++
Sbjct: 1925 DTLRSKEQAELEAARQRQLAAEEERRRREA-----EERVQKSLAAEEEAARQRKAALEEV 1979
Query: 596 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 655
E+ A+++E + ER +E A++ A +E +R Q EE +QQ+E+E
Sbjct: 1980 ERLKAKVEEA--RRLRERAEQESARQLQLA---QEAAQKRLQAEEKAHAFAVQQKEQEL- 2033
Query: 656 HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQ----ERREQERREQ 711
Q+ LQ+++ + +A A+R AE+ E+ R + ER + R Q ER +Q EQ
Sbjct: 2034 -QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2092
Query: 712 ERQLAEQERRREQERLQAERELQER---EKALRLQKEQLQRELEEKKKKEEQQRLAERQL 768
+ A+ + E+ R +AE+E R E+A QK+ E+E+ KK EQ + Q+
Sbjct: 2093 AQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2152
Query: 769 QEE 771
++E
Sbjct: 2153 EQE 2155
Score = 93.6 bits (231), Expect = 8e-19
Identities = 87/327 (26%), Positives = 161/327 (49%), Gaps = 29/327 (8%)
Query: 531 KEKERQRLENLRRKEEA--EQLRRQKVEEDKRRRL---EEVKLKREERLRKVLQARERVE 585
+ KE+ LE R+++ A E+ RR++ EE ++ L EE +R+ L +V + + +VE
Sbjct: 1928 RSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE 1987
Query: 586 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE------ 639
+ + +++ ++ Q+ E A++ AEEKA A +K +E++ +QE+
Sbjct: 1988 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2047
Query: 640 --EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 697
EA R +E EE R +Q ++E Q R R+ EA+RL +Q +E+ + + Q
Sbjct: 2048 RGEAEAARRAAEEAEEAR----VQAEREAAQSR-RQVEEAERL-KQSAEEQAQARAQAQA 2101
Query: 698 RREQERREQERREQERQLAEQERRREQERLQAERELQER--EKALRLQKEQLQRELEEKK 755
E+ R+E E+ R AEQ R+++ AE E ++ E+ LR QK Q+++EL +
Sbjct: 2102 AAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR-QKAQVEQELTTLR 2160
Query: 756 KKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKINP 815
+ E+ + L EE ++ EA A++ + V+ + + + +I
Sbjct: 2161 LQLEETDHQKNLLDEELQRLKAEATEAARQRS---QVEEELFSVRVQMEELSKLKARIEA 2217
Query: 816 DNYGMDLNSDDST----DDEAHPRKPI 838
+N + L D+T +EA K +
Sbjct: 2218 ENRALILRDKDNTQRFLQEEAEKMKQV 2244
Score = 89.0 bits (219), Expect = 2e-17
Identities = 77/277 (27%), Positives = 135/277 (48%), Gaps = 18/277 (6%)
Query: 513 RSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE 572
R + ++ + + KE +++ E + R+EEA ++ KR EE++ R+
Sbjct: 1341 RQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV----DAQQQKRSIQEELQQLRQS 1396
Query: 573 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 632
++ QA+ R + E + +IE++ + + E + +R E + +A + EE E
Sbjct: 1397 SEAEI-QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAE-GELQALRARAEEAE 1454
Query: 633 A--RRKQEEEARRLRWLQQEEEERRHQ---ELLQKKKEE-----EQERLRKAAEAKRLAE 682
A R+ Q EEA RLR Q+E +R+ Q EL + K E E++R +A E RL
Sbjct: 1455 AQKRQAQ-EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQA 1513
Query: 683 QREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRL 742
+ + R Q E+ R+ Q E +R E +L + ++ Q ER LQE A+
Sbjct: 1514 EEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ 1573
Query: 743 QKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 779
+E+ +R +++ + E + AER+L E + KA EA
Sbjct: 1574 LREEAERRAQQQAEAERAREEAEREL-ERWQLKANEA 1609
Score = 87.4 bits (215), Expect = 5e-17
Identities = 138/560 (24%), Positives = 235/560 (41%), Gaps = 117/560 (20%)
Query: 316 QVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQ 375
Q L Q+ S++ + A+RR A++ E + R S R E + S +
Sbjct: 2035 QTLQQEQSVLDQLRGEAE-AARRAAEEAEEARVQAEREAAQS---RRQVEEAERLKQSAE 2090
Query: 376 KEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTD 435
++ A+ AAAE E + E A + A + A ++ K
Sbjct: 2091 EQAQARAQAQAAAEKLRKEA---------EQEAARRAQAEQAALRQKQAADAEMEKHKKF 2141
Query: 436 QADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTF 495
R+ Q + + + + E D +++L DEELQ +++ + S+V L +
Sbjct: 2142 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2201
Query: 496 LHTVQRNQMLMTPTSAPRSVMKSFIKRNTP-LRMDPKEKERQRLENLRR----KEEAEQL 550
++ L A + K NT + EK +Q E R +EA +L
Sbjct: 2202 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2261
Query: 551 RRQKVEED--KRRRLEEVKLKREERLRKVLQAR------ERVEQMKE----------EKK 592
R Q EED ++R L E LK E+++ V +A E ++Q KE E K
Sbjct: 2262 R-QLAEEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK 2318
Query: 593 KQIEQKFAQIDE---KTEKAKEERLAEEKAKKKAAAKKMEEVE-ARRKQEEEARRLRWLQ 648
+Q+ Q+ A+ + +T +A+ +R E A+ + ++ E+ A+ + EE+A+R R
Sbjct: 2319 EQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQA 2378
Query: 649 QEEEERRHQ---------------ELLQKKKEEEQERLRKA-AEAKRLAEQREQERR--- 689
+E E+ H+ E+ +++ + + ERLR+A AE +R E+ +QE +
Sbjct: 2379 EEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2438
Query: 690 ---------------------------------------EQERREQER-------REQER 703
EQE+ + E+ + Q+
Sbjct: 2439 LKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL 2498
Query: 704 REQERREQERQLAEQERRR------EQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
RE+++R+Q++ EQER+R E R Q E E R K LQ+ + QR +E+
Sbjct: 2499 REEQQRQQQQM--EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLA 2556
Query: 758 EEQQRLAER-QLQEEQEKKA 776
EE QRL E+ QL EEQ + A
Sbjct: 2557 EENQRLREQLQLLEEQHRAA 2576
Score = 86.7 bits (213), Expect = 9e-17
Identities = 98/403 (24%), Positives = 185/403 (45%), Gaps = 53/403 (13%)
Query: 445 QSARRKRSYKQAVSELDEEQHLED--------EELQPPRSKTPSSPCPASKVVRPLRTFL 496
Q ARR++ QA+ D + E EE++ K A + + ++ +
Sbjct: 1192 QDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYE 1251
Query: 497 HTVQRNQMLMTPTSAP------RSVMKSFIKRNTPLRMDPKEKERQRL-------ENLRR 543
+ + + P ++P +S +S I+ LR E E LRR
Sbjct: 1252 LQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRR 1311
Query: 544 KEEAEQLRRQKVEEDKRRRLE-EVKLKREERLRKV-LQARERVEQMKEEKKKQIEQKFAQ 601
EE E+L Q+ E++ R E E L+++ +L + QA+ + E+ +E +++++++ +
Sbjct: 1312 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1371
Query: 602 IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQ 661
+E A++++ + ++ ++ E++A+ +Q E A R R L+ EEE R +
Sbjct: 1372 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR-LRIEEEIR-----VV 1425
Query: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 721
+ + E ER R AE E + R +E Q+R+ QE E+ RR Q+ ++ +R
Sbjct: 1426 RLQLEATERQRGGAEG----ELQALRARAEEAEAQKRQAQEEAERLRR----QVQDESQR 1477
Query: 722 REQ------ERLQAERE-LQEREKA------LRLQKEQLQREL---EEKKKKEEQQRLAE 765
+ Q R++AE E +E+++A LRLQ E+ +R L E ++ ++ Q L
Sbjct: 1478 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALET 1537
Query: 766 RQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHR 808
Q E E ++K A+ A K + +Q Q+ + R
Sbjct: 1538 AQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER 1580
Score = 86.7 bits (213), Expect = 9e-17
Identities = 120/544 (22%), Positives = 218/544 (40%), Gaps = 79/544 (14%)
Query: 299 DSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSY 358
+SQ R + + +S +V A+ + KQ ++ RL + AE R + +
Sbjct: 1474 ESQRKRQAEVELAS---RVKAEAEAAREKQRALQALEELRLQAEEAE------RRLRQAE 1524
Query: 359 LERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPA 418
+ER V+V + E +++ + AE S +A +
Sbjct: 1525 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER---SLQEEHVAVAQLREEAERR 1581
Query: 419 ASSPETPSAGQQEA---------KTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDE 469
A ++EA K ++A R + +++S QA +E +E E E
Sbjct: 1582 AQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKE---EAE 1638
Query: 470 ELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMD 529
R K + VR +++ + L T+ R + + R LR +
Sbjct: 1639 REARRRGKAEE------QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR---LRAE 1689
Query: 530 PKEKERQR------LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER 583
++ E+QR L L+R+ A +RQ++E + L +V+ + E L +A E
Sbjct: 1690 TEQGEQQRQLLEEELARLQREAAAATQKRQELEAE----LAKVRAEMEVLLASKARAEEE 1745
Query: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE--- 640
E+ K+++E + + E E+A R E+AK++ + EE AR++ E E
Sbjct: 1746 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQR--QLAEEDAARQRAEAERVL 1803
Query: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
A +L + + + E+ K+KE E ERLR+ AE + +R +E+ Q + + E R
Sbjct: 1804 AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL 1863
Query: 701 QERREQERREQERQLA------EQERRREQE-------------------------RLQA 729
+ R+ E ERQ Q R+ E+E R A
Sbjct: 1864 AQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA 1923
Query: 730 ERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVT 789
E L+ +E+A Q Q EE++++ E + ++ L E+E + A + +
Sbjct: 1924 EDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLK 1983
Query: 790 VDVQ 793
V+
Sbjct: 1984 AKVE 1987
Score = 82.8 bits (203), Expect = 1e-15
Identities = 119/525 (22%), Positives = 224/525 (42%), Gaps = 92/525 (17%)
Query: 319 AQKYSLVAKQESVVRRASRRLAKK-TAEEPAASGRIICHSYLERLL-------------- 363
A++ L A++E R A R+ K AEE AA R +ERL
Sbjct: 1938 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 1997
Query: 364 -----NVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPA 418
+++ Q+ ++ + E+A A + E + + + + A
Sbjct: 1998 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE---QELQQTLQQEQSVLDQLRGEAEAA 2054
Query: 419 ASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKT 478
+ E + +A+ + A R+ ++ R K+S ++ + Q ++ + +
Sbjct: 2055 RRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2114
Query: 479 PSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRL 538
+R + +++++ T ++ ++ + T LR+ +E + Q+
Sbjct: 2115 ARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQEL---TTLRLQLEETDHQKN 2171
Query: 539 ---ENLRR-KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 594
E L+R K EA + RQ+ + ++ V+++ +L+ ++A R +++ K
Sbjct: 2172 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD---KD 2228
Query: 595 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 654
Q+F Q E+ EK K+ +AEE A+ AA +EA RLR L +E+ +
Sbjct: 2229 NTQRFLQ--EEAEKMKQ--VAEEAARLSVAA-------------QEAARLRQLAEEDLAQ 2271
Query: 655 RH---QELLQKKKEEEQERLRKAAEAKRLAEQR----EQERREQERREQERRE------- 700
+ +++L++K + QE R AEA+ L +Q+ EQ RR QE +EQ ++
Sbjct: 2272 QRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2331
Query: 701 -QERREQERREQERQLAEQER-------------RREQE----RLQAER--------ELQ 734
Q E ER+ Q AE ER R E++ R QAE EL
Sbjct: 2332 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2391
Query: 735 EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 779
+EK +Q ++QR+ + + ++ +AE L+ E+EK +EA
Sbjct: 2392 TQEKVTLVQTLEIQRQQSDHDAERLREAIAE--LEREKEKLQQEA 2434
Score = 75.1 bits (183), Expect = 3e-13
Identities = 70/275 (25%), Positives = 129/275 (46%), Gaps = 16/275 (5%)
Query: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL--KREERLRKVLQARERVEQMKE 589
E ERQR + + E +LR ++ + R E+ + K+ E + + L E Q K
Sbjct: 2337 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKV 2396
Query: 590 EKKKQIEQKFAQIDEKTEKAKEE--RLAEEKAKKKAAAK--KMEEVEARRKQEEEARRLR 645
+ +E + Q D E+ +E L EK K + AK +++ E + Q+E+ +
Sbjct: 2397 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQET 2456
Query: 646 WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR- 704
Q+ LLQ+++ EQE+ + + + +Q R EQ+R++Q+ ++ +R
Sbjct: 2457 QALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRL 2516
Query: 705 ---EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 761
+E R ++ + E RR+++E Q E++ +++E+ L E+ QR E+ + EEQ
Sbjct: 2517 VASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL---AEENQRLREQLQLLEEQH 2573
Query: 762 RLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPA 796
R A L +E A + A N + PA
Sbjct: 2574 RAA---LAHSEEVTASQVAATKTLPNGRDALDGPA 2605
Score = 65.5 bits (158), Expect = 2e-10
Identities = 80/345 (23%), Positives = 153/345 (44%), Gaps = 46/345 (13%)
Query: 433 KTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPL 492
+T +A+ R+ SA +R K V+E+ Q +E+ Q R + A ++ L
Sbjct: 2334 RTLEAERQRQLEMSAEAER-LKLRVAEMSRAQARAEEDAQRFRKQ-------AEEIGEKL 2385
Query: 493 -RTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLR 551
RT L T ++ ++ T ++ + + +RL + E E+ +
Sbjct: 2386 HRTELATQEKVTLVQT----------------LEIQRQQSDHDAERLREAIAELEREKEK 2429
Query: 552 RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 611
Q+ + + + EE++ ++E+L LQ + ++Q +K + Q+ I++ EKAK
Sbjct: 2430 LQQEAKLLQLKSEEMQTVQQEQL---LQETQALQQSFLSEKDSLLQRERFIEQ--EKAKL 2484
Query: 612 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERL 671
E+L +++ K A+++ E + R++Q+ E R R + EE RR Q ++ +QE L
Sbjct: 2485 EQLFQDEVAK---AQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL 2541
Query: 672 RKAAEAKRLAEQREQERREQERREQERREQERRE-QERREQERQLAEQERRREQERLQAE 730
+Q EQ+RR+QE E ++ R + Q EQ R ++ A
Sbjct: 2542 ----------QQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAAT 2591
Query: 731 RELQEREKAL--RLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE 773
+ L AL + + + + ++K QRL E + +E
Sbjct: 2592 KTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEE 2636
Score = 47.4 bits (111), Expect = 6e-05
Identities = 61/278 (21%), Positives = 128/278 (46%), Gaps = 35/278 (12%)
Query: 541 LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR---KVLQARERVEQMKEEKKKQIEQ 597
+R + AE++ R E+ K + L E + K L+A+ +Q + + +
Sbjct: 1063 IRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELR 1122
Query: 598 KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA--------RRKQEEEARRLRWLQQ 649
++ E+ ++ ER E + ++ A+ +E +A +R+ E+ R+LR+ +
Sbjct: 1123 GAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYR- 1181
Query: 650 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR--EQERREQERREQERREQE 707
E + L ++ +EQ + A+++ + EQ QE+ E+ R E+ E+ +R +
Sbjct: 1182 ESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAK 1241
Query: 708 R-----REQERQLAEQERRRE-------QERLQ--AERELQE-------REKALRLQKEQ 746
+ ++ E QL + + E + ++Q +E +QE + L +
Sbjct: 1242 QYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQY 1301
Query: 747 LQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 784
++ E ++ EE++RLAE+Q EE+E+ A+ A K
Sbjct: 1302 IKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEK 1339
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 102 bits (253), Expect = 2e-21
Identities = 100/387 (25%), Positives = 182/387 (47%), Gaps = 34/387 (8%)
Query: 418 AASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSK 477
A + + + ++EAK Q R + RR+ + AV +++ +++E Q +S
Sbjct: 1513 AEAHAQAKAQAEREAKELQQ---RMQEEVVRREEA---AVDAQQQKRSIQEELQQLRQSS 1566
Query: 478 TPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQR 537
A + R+ L + +++ A LR +E E Q+
Sbjct: 1567 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1626
Query: 538 LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERL--------RKVLQARERVEQMKE 589
+ +EEAE+LRRQ +E +R+R EV+L + ++ LQA E + E
Sbjct: 1627 RQ---AQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1683
Query: 590 EKKKQIEQ----KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 645
E ++++ Q + Q+ E A+ AE ++K+ + A+K ++E R +EE +
Sbjct: 1684 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE--RSLQEEHVAVA 1741
Query: 646 WLQQEEEERRHQELLQKKKEEEQER-----LRKAAEAKRL---AEQREQERREQERREQE 697
L++E E R Q+ ++ EE ER KA EA RL AE+ Q++ + ++
Sbjct: 1742 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1801
Query: 698 RREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
++E+ RE RR + + A ++R ++ L+ +R+L E RL EQ L + ++
Sbjct: 1802 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQ 1861
Query: 758 EEQQRLAERQLQEEQEKKAKEAAGASK 784
EQQR + L+EE + +EAA A++
Sbjct: 1862 GEQQR---QLLEEELARLQREAAAATQ 1885
Score = 96.7 bits (239), Expect = 9e-20
Identities = 150/595 (25%), Positives = 258/595 (43%), Gaps = 118/595 (19%)
Query: 296 SRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAK-QESVVRRASRRL----AKKTAEEPAAS 350
+ + QS R S ++ + L +++ VA+ +E RRA ++ A++ AE
Sbjct: 1711 AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELER 1770
Query: 351 GRIICHSYLE-RLLNVEVPQKVG---SEQKEPPEEAEPVA-----AAEPEVPENNGNNSW 401
++ + L RL EV Q+ +E ++ EEAE A A E V +
Sbjct: 1771 WQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE 1830
Query: 402 PHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELD 461
++A T + AA + A+T+Q + R+ + R ++A +
Sbjct: 1831 LEKQRQLAEGTAQQRLAAEQELI----RLRAETEQGEQQRQLLEE-ELARLQREAAAATQ 1885
Query: 462 EEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIK 521
+ Q LE EL R++ ++ R+ T ++++ + A + +
Sbjct: 1886 KRQELE-AELAKVRAEMEVLLASKARAEEESRS---TSEKSKQRL---EAEAGRFRELAE 1938
Query: 522 RNTPLRMDPKEKERQRL----ENLRRKEEAEQLRRQKV----EEDKRRRLEEVKLKREE- 572
LR +E +RQR + R++ EAE++ +K+ E + + E+ LK +E
Sbjct: 1939 EAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEA 1998
Query: 573 ---RLRKVLQ----ARERVEQMKEEKKKQIEQKFAQI----DEKTEKAK----------- 610
RLR++ + R R+E+ + K IE++ AQ+ D + E+ K
Sbjct: 1999 ENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR 2058
Query: 611 ---EERLAEEKAKKKAAAKKME--------------EVEARRKQEEEARRLRWLQQEEEE 653
EE LA + + +KAAA K E + ++ + E EA R R L EEE
Sbjct: 2059 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 2118
Query: 654 RRHQ--ELLQKK--KEEEQERLRKAA------------EAKRLAEQREQERREQ------ 691
RR + E +QK EEE R RKAA EA+RL E+ EQE Q
Sbjct: 2119 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2178
Query: 692 -----------------ERREQERREQERREQERREQERQLAEQERR----REQERLQAE 730
+++EQE ++ ++EQ +Q R AE RR E+ R+QAE
Sbjct: 2179 AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE 2238
Query: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKA 785
RE + + + + E+L++ EE+ + Q + A +L++E E++A A A +A
Sbjct: 2239 REAAQSRRQVE-EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQA 2292
Score = 94.4 bits (233), Expect = 4e-19
Identities = 75/243 (30%), Positives = 127/243 (52%), Gaps = 22/243 (9%)
Query: 539 ENLRRKEEAE---QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI 595
+ LR KE+AE +RQ E++RRR E EER++K L A E + ++ +++
Sbjct: 2094 DTLRSKEQAELEAARQRQLAAEEERRRREA-----EERVQKSLAAEEEAARQRKAALEEV 2148
Query: 596 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 655
E+ A+++E + ER +E A++ A +E +R Q EE +QQ+E+E
Sbjct: 2149 ERLKAKVEEA--RRLRERAEQESARQLQLA---QEAAQKRLQAEEKAHAFAVQQKEQEL- 2202
Query: 656 HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQ----ERREQERREQ 711
Q+ LQ+++ + +A A+R AE+ E+ R + ER + R Q ER +Q EQ
Sbjct: 2203 -QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2261
Query: 712 ERQLAEQERRREQERLQAERELQER---EKALRLQKEQLQRELEEKKKKEEQQRLAERQL 768
+ A+ + E+ R +AE+E R E+A QK+ E+E+ KK EQ + Q+
Sbjct: 2262 AQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2321
Query: 769 QEE 771
++E
Sbjct: 2322 EQE 2324
Score = 93.6 bits (231), Expect = 8e-19
Identities = 87/327 (26%), Positives = 161/327 (49%), Gaps = 29/327 (8%)
Query: 531 KEKERQRLENLRRKEEA--EQLRRQKVEEDKRRRL---EEVKLKREERLRKVLQARERVE 585
+ KE+ LE R+++ A E+ RR++ EE ++ L EE +R+ L +V + + +VE
Sbjct: 2097 RSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE 2156
Query: 586 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE------ 639
+ + +++ ++ Q+ E A++ AEEKA A +K +E++ +QE+
Sbjct: 2157 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2216
Query: 640 --EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 697
EA R +E EE R +Q ++E Q R R+ EA+RL +Q +E+ + + Q
Sbjct: 2217 RGEAEAARRAAEEAEEAR----VQAEREAAQSR-RQVEEAERL-KQSAEEQAQARAQAQA 2270
Query: 698 RREQERREQERREQERQLAEQERRREQERLQAERELQER--EKALRLQKEQLQRELEEKK 755
E+ R+E E+ R AEQ R+++ AE E ++ E+ LR QK Q+++EL +
Sbjct: 2271 AAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR-QKAQVEQELTTLR 2329
Query: 756 KKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKINP 815
+ E+ + L EE ++ EA A++ + V+ + + + +I
Sbjct: 2330 LQLEETDHQKNLLDEELQRLKAEATEAARQRS---QVEEELFSVRVQMEELSKLKARIEA 2386
Query: 816 DNYGMDLNSDDST----DDEAHPRKPI 838
+N + L D+T +EA K +
Sbjct: 2387 ENRALILRDKDNTQRFLQEEAEKMKQV 2413
Score = 89.0 bits (219), Expect = 2e-17
Identities = 77/277 (27%), Positives = 135/277 (48%), Gaps = 18/277 (6%)
Query: 513 RSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE 572
R + ++ + + KE +++ E + R+EEA ++ KR EE++ R+
Sbjct: 1510 RQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV----DAQQQKRSIQEELQQLRQS 1565
Query: 573 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 632
++ QA+ R + E + +IE++ + + E + +R E + +A + EE E
Sbjct: 1566 SEAEI-QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAE-GELQALRARAEEAE 1623
Query: 633 A--RRKQEEEARRLRWLQQEEEERRHQ---ELLQKKKEE-----EQERLRKAAEAKRLAE 682
A R+ Q EEA RLR Q+E +R+ Q EL + K E E++R +A E RL
Sbjct: 1624 AQKRQAQ-EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQA 1682
Query: 683 QREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRL 742
+ + R Q E+ R+ Q E +R E +L + ++ Q ER LQE A+
Sbjct: 1683 EEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ 1742
Query: 743 QKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 779
+E+ +R +++ + E + AER+L E + KA EA
Sbjct: 1743 LREEAERRAQQQAEAERAREEAEREL-ERWQLKANEA 1778
Score = 87.4 bits (215), Expect = 5e-17
Identities = 138/560 (24%), Positives = 235/560 (41%), Gaps = 117/560 (20%)
Query: 316 QVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQ 375
Q L Q+ S++ + A+RR A++ E + R S R E + S +
Sbjct: 2204 QTLQQEQSVLDQLRGEAE-AARRAAEEAEEARVQAEREAAQS---RRQVEEAERLKQSAE 2259
Query: 376 KEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTD 435
++ A+ AAAE E + E A + A + A ++ K
Sbjct: 2260 EQAQARAQAQAAAEKLRKEA---------EQEAARRAQAEQAALRQKQAADAEMEKHKKF 2310
Query: 436 QADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTF 495
R+ Q + + + + E D +++L DEELQ +++ + S+V L +
Sbjct: 2311 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2370
Query: 496 LHTVQRNQMLMTPTSAPRSVMKSFIKRNTP-LRMDPKEKERQRLENLRR----KEEAEQL 550
++ L A + K NT + EK +Q E R +EA +L
Sbjct: 2371 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2430
Query: 551 RRQKVEED--KRRRLEEVKLKREERLRKVLQAR------ERVEQMKE----------EKK 592
R Q EED ++R L E LK E+++ V +A E ++Q KE E K
Sbjct: 2431 R-QLAEEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK 2487
Query: 593 KQIEQKFAQIDE---KTEKAKEERLAEEKAKKKAAAKKMEEVE-ARRKQEEEARRLRWLQ 648
+Q+ Q+ A+ + +T +A+ +R E A+ + ++ E+ A+ + EE+A+R R
Sbjct: 2488 EQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQA 2547
Query: 649 QEEEERRHQ---------------ELLQKKKEEEQERLRKA-AEAKRLAEQREQERR--- 689
+E E+ H+ E+ +++ + + ERLR+A AE +R E+ +QE +
Sbjct: 2548 EEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2607
Query: 690 ---------------------------------------EQERREQER-------REQER 703
EQE+ + E+ + Q+
Sbjct: 2608 LKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL 2667
Query: 704 REQERREQERQLAEQERRR------EQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
RE+++R+Q++ EQER+R E R Q E E R K LQ+ + QR +E+
Sbjct: 2668 REEQQRQQQQM--EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLA 2725
Query: 758 EEQQRLAER-QLQEEQEKKA 776
EE QRL E+ QL EEQ + A
Sbjct: 2726 EENQRLREQLQLLEEQHRAA 2745
Score = 86.7 bits (213), Expect = 9e-17
Identities = 98/403 (24%), Positives = 185/403 (45%), Gaps = 53/403 (13%)
Query: 445 QSARRKRSYKQAVSELDEEQHLED--------EELQPPRSKTPSSPCPASKVVRPLRTFL 496
Q ARR++ QA+ D + E EE++ K A + + ++ +
Sbjct: 1361 QDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYE 1420
Query: 497 HTVQRNQMLMTPTSAP------RSVMKSFIKRNTPLRMDPKEKERQRL-------ENLRR 543
+ + + P ++P +S +S I+ LR E E LRR
Sbjct: 1421 LQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRR 1480
Query: 544 KEEAEQLRRQKVEEDKRRRLE-EVKLKREERLRKV-LQARERVEQMKEEKKKQIEQKFAQ 601
EE E+L Q+ E++ R E E L+++ +L + QA+ + E+ +E +++++++ +
Sbjct: 1481 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1540
Query: 602 IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQ 661
+E A++++ + ++ ++ E++A+ +Q E A R R L+ EEE R +
Sbjct: 1541 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR-LRIEEEIR-----VV 1594
Query: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 721
+ + E ER R AE E + R +E Q+R+ QE E+ RR Q+ ++ +R
Sbjct: 1595 RLQLEATERQRGGAEG----ELQALRARAEEAEAQKRQAQEEAERLRR----QVQDESQR 1646
Query: 722 REQ------ERLQAERE-LQEREKA------LRLQKEQLQREL---EEKKKKEEQQRLAE 765
+ Q R++AE E +E+++A LRLQ E+ +R L E ++ ++ Q L
Sbjct: 1647 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALET 1706
Query: 766 RQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHR 808
Q E E ++K A+ A K + +Q Q+ + R
Sbjct: 1707 AQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER 1749
Score = 86.7 bits (213), Expect = 9e-17
Identities = 120/544 (22%), Positives = 218/544 (40%), Gaps = 79/544 (14%)
Query: 299 DSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSY 358
+SQ R + + +S +V A+ + KQ ++ RL + AE R + +
Sbjct: 1643 ESQRKRQAEVELAS---RVKAEAEAAREKQRALQALEELRLQAEEAE------RRLRQAE 1693
Query: 359 LERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPA 418
+ER V+V + E +++ + AE S +A +
Sbjct: 1694 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER---SLQEEHVAVAQLREEAERR 1750
Query: 419 ASSPETPSAGQQEA---------KTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDE 469
A ++EA K ++A R + +++S QA +E +E E E
Sbjct: 1751 AQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKE---EAE 1807
Query: 470 ELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMD 529
R K + VR +++ + L T+ R + + R LR +
Sbjct: 1808 REARRRGKAEE------QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR---LRAE 1858
Query: 530 PKEKERQR------LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER 583
++ E+QR L L+R+ A +RQ++E + L +V+ + E L +A E
Sbjct: 1859 TEQGEQQRQLLEEELARLQREAAAATQKRQELEAE----LAKVRAEMEVLLASKARAEEE 1914
Query: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE--- 640
E+ K+++E + + E E+A R E+AK++ + EE AR++ E E
Sbjct: 1915 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQR--QLAEEDAARQRAEAERVL 1972
Query: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
A +L + + + E+ K+KE E ERLR+ AE + +R +E+ Q + + E R
Sbjct: 1973 AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL 2032
Query: 701 QERREQERREQERQLA------EQERRREQE-------------------------RLQA 729
+ R+ E ERQ Q R+ E+E R A
Sbjct: 2033 AQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA 2092
Query: 730 ERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVT 789
E L+ +E+A Q Q EE++++ E + ++ L E+E + A + +
Sbjct: 2093 EDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLK 2152
Query: 790 VDVQ 793
V+
Sbjct: 2153 AKVE 2156
Score = 82.8 bits (203), Expect = 1e-15
Identities = 119/525 (22%), Positives = 224/525 (42%), Gaps = 92/525 (17%)
Query: 319 AQKYSLVAKQESVVRRASRRLAKK-TAEEPAASGRIICHSYLERLL-------------- 363
A++ L A++E R A R+ K AEE AA R +ERL
Sbjct: 2107 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2166
Query: 364 -----NVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPA 418
+++ Q+ ++ + E+A A + E + + + + A
Sbjct: 2167 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE---QELQQTLQQEQSVLDQLRGEAEAA 2223
Query: 419 ASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKT 478
+ E + +A+ + A R+ ++ R K+S ++ + Q ++ + +
Sbjct: 2224 RRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2283
Query: 479 PSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRL 538
+R + +++++ T ++ ++ + T LR+ +E + Q+
Sbjct: 2284 ARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQEL---TTLRLQLEETDHQKN 2340
Query: 539 ---ENLRR-KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 594
E L+R K EA + RQ+ + ++ V+++ +L+ ++A R +++ K
Sbjct: 2341 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD---KD 2397
Query: 595 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 654
Q+F Q E+ EK K+ +AEE A+ AA +EA RLR L +E+ +
Sbjct: 2398 NTQRFLQ--EEAEKMKQ--VAEEAARLSVAA-------------QEAARLRQLAEEDLAQ 2440
Query: 655 RH---QELLQKKKEEEQERLRKAAEAKRLAEQR----EQERREQERREQERRE------- 700
+ +++L++K + QE R AEA+ L +Q+ EQ RR QE +EQ ++
Sbjct: 2441 QRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2500
Query: 701 -QERREQERREQERQLAEQER-------------RREQE----RLQAER--------ELQ 734
Q E ER+ Q AE ER R E++ R QAE EL
Sbjct: 2501 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2560
Query: 735 EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 779
+EK +Q ++QR+ + + ++ +AE L+ E+EK +EA
Sbjct: 2561 TQEKVTLVQTLEIQRQQSDHDAERLREAIAE--LEREKEKLQQEA 2603
Score = 75.1 bits (183), Expect = 3e-13
Identities = 70/275 (25%), Positives = 129/275 (46%), Gaps = 16/275 (5%)
Query: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL--KREERLRKVLQARERVEQMKE 589
E ERQR + + E +LR ++ + R E+ + K+ E + + L E Q K
Sbjct: 2506 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKV 2565
Query: 590 EKKKQIEQKFAQIDEKTEKAKEE--RLAEEKAKKKAAAK--KMEEVEARRKQEEEARRLR 645
+ +E + Q D E+ +E L EK K + AK +++ E + Q+E+ +
Sbjct: 2566 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQET 2625
Query: 646 WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR- 704
Q+ LLQ+++ EQE+ + + + +Q R EQ+R++Q+ ++ +R
Sbjct: 2626 QALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRL 2685
Query: 705 ---EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 761
+E R ++ + E RR+++E Q E++ +++E+ L E+ QR E+ + EEQ
Sbjct: 2686 VASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL---AEENQRLREQLQLLEEQH 2742
Query: 762 RLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPA 796
R A L +E A + A N + PA
Sbjct: 2743 RAA---LAHSEEVTASQVAATKTLPNGRDALDGPA 2774
Score = 65.5 bits (158), Expect = 2e-10
Identities = 80/345 (23%), Positives = 153/345 (44%), Gaps = 46/345 (13%)
Query: 433 KTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPL 492
+T +A+ R+ SA +R K V+E+ Q +E+ Q R + A ++ L
Sbjct: 2503 RTLEAERQRQLEMSAEAER-LKLRVAEMSRAQARAEEDAQRFRKQ-------AEEIGEKL 2554
Query: 493 -RTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLR 551
RT L T ++ ++ T ++ + + +RL + E E+ +
Sbjct: 2555 HRTELATQEKVTLVQT----------------LEIQRQQSDHDAERLREAIAELEREKEK 2598
Query: 552 RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 611
Q+ + + + EE++ ++E+L LQ + ++Q +K + Q+ I++ EKAK
Sbjct: 2599 LQQEAKLLQLKSEEMQTVQQEQL---LQETQALQQSFLSEKDSLLQRERFIEQ--EKAKL 2653
Query: 612 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERL 671
E+L +++ K A+++ E + R++Q+ E R R + EE RR Q ++ +QE L
Sbjct: 2654 EQLFQDEVAK---AQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL 2710
Query: 672 RKAAEAKRLAEQREQERREQERREQERREQERRE-QERREQERQLAEQERRREQERLQAE 730
+Q EQ+RR+QE E ++ R + Q EQ R ++ A
Sbjct: 2711 ----------QQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAAT 2760
Query: 731 RELQEREKAL--RLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE 773
+ L AL + + + + ++K QRL E + +E
Sbjct: 2761 KTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEE 2805
Score = 47.4 bits (111), Expect = 6e-05
Identities = 61/278 (21%), Positives = 128/278 (46%), Gaps = 35/278 (12%)
Query: 541 LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR---KVLQARERVEQMKEEKKKQIEQ 597
+R + AE++ R E+ K + L E + K L+A+ +Q + + +
Sbjct: 1232 IRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELR 1291
Query: 598 KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA--------RRKQEEEARRLRWLQQ 649
++ E+ ++ ER E + ++ A+ +E +A +R+ E+ R+LR+ +
Sbjct: 1292 GAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYR- 1350
Query: 650 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR--EQERREQERREQERREQE 707
E + L ++ +EQ + A+++ + EQ QE+ E+ R E+ E+ +R +
Sbjct: 1351 ESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAK 1410
Query: 708 R-----REQERQLAEQERRRE-------QERLQ--AERELQE-------REKALRLQKEQ 746
+ ++ E QL + + E + ++Q +E +QE + L +
Sbjct: 1411 QYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQY 1470
Query: 747 LQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 784
++ E ++ EE++RLAE+Q EE+E+ A+ A K
Sbjct: 1471 IKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEK 1508
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 102 bits (253), Expect = 2e-21
Identities = 100/387 (25%), Positives = 182/387 (47%), Gaps = 34/387 (8%)
Query: 418 AASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSK 477
A + + + ++EAK Q R + RR+ + AV +++ +++E Q +S
Sbjct: 1354 AEAHAQAKAQAEREAKELQQ---RMQEEVVRREEA---AVDAQQQKRSIQEELQQLRQSS 1407
Query: 478 TPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQR 537
A + R+ L + +++ A LR +E E Q+
Sbjct: 1408 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1467
Query: 538 LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERL--------RKVLQARERVEQMKE 589
+ +EEAE+LRRQ +E +R+R EV+L + ++ LQA E + E
Sbjct: 1468 RQ---AQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1524
Query: 590 EKKKQIEQ----KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 645
E ++++ Q + Q+ E A+ AE ++K+ + A+K ++E R +EE +
Sbjct: 1525 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE--RSLQEEHVAVA 1582
Query: 646 WLQQEEEERRHQELLQKKKEEEQER-----LRKAAEAKRL---AEQREQERREQERREQE 697
L++E E R Q+ ++ EE ER KA EA RL AE+ Q++ + ++
Sbjct: 1583 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1642
Query: 698 RREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
++E+ RE RR + + A ++R ++ L+ +R+L E RL EQ L + ++
Sbjct: 1643 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQ 1702
Query: 758 EEQQRLAERQLQEEQEKKAKEAAGASK 784
EQQR + L+EE + +EAA A++
Sbjct: 1703 GEQQR---QLLEEELARLQREAAAATQ 1726
Score = 96.7 bits (239), Expect = 9e-20
Identities = 150/595 (25%), Positives = 258/595 (43%), Gaps = 118/595 (19%)
Query: 296 SRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAK-QESVVRRASRRL----AKKTAEEPAAS 350
+ + QS R S ++ + L +++ VA+ +E RRA ++ A++ AE
Sbjct: 1552 AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELER 1611
Query: 351 GRIICHSYLE-RLLNVEVPQKVG---SEQKEPPEEAEPVA-----AAEPEVPENNGNNSW 401
++ + L RL EV Q+ +E ++ EEAE A A E V +
Sbjct: 1612 WQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE 1671
Query: 402 PHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELD 461
++A T + AA + A+T+Q + R+ + R ++A +
Sbjct: 1672 LEKQRQLAEGTAQQRLAAEQELI----RLRAETEQGEQQRQLLEE-ELARLQREAAAATQ 1726
Query: 462 EEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIK 521
+ Q LE EL R++ ++ R+ T ++++ + A + +
Sbjct: 1727 KRQELE-AELAKVRAEMEVLLASKARAEEESRS---TSEKSKQRL---EAEAGRFRELAE 1779
Query: 522 RNTPLRMDPKEKERQRL----ENLRRKEEAEQLRRQKV----EEDKRRRLEEVKLKREE- 572
LR +E +RQR + R++ EAE++ +K+ E + + E+ LK +E
Sbjct: 1780 EAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEA 1839
Query: 573 ---RLRKVLQ----ARERVEQMKEEKKKQIEQKFAQI----DEKTEKAK----------- 610
RLR++ + R R+E+ + K IE++ AQ+ D + E+ K
Sbjct: 1840 ENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1899
Query: 611 ---EERLAEEKAKKKAAAKKME--------------EVEARRKQEEEARRLRWLQQEEEE 653
EE LA + + +KAAA K E + ++ + E EA R R L EEE
Sbjct: 1900 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1959
Query: 654 RRHQ--ELLQKK--KEEEQERLRKAA------------EAKRLAEQREQERREQ------ 691
RR + E +QK EEE R RKAA EA+RL E+ EQE Q
Sbjct: 1960 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2019
Query: 692 -----------------ERREQERREQERREQERREQERQLAEQERR----REQERLQAE 730
+++EQE ++ ++EQ +Q R AE RR E+ R+QAE
Sbjct: 2020 AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE 2079
Query: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKA 785
RE + + + + E+L++ EE+ + Q + A +L++E E++A A A +A
Sbjct: 2080 REAAQSRRQVE-EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQA 2133
Score = 94.4 bits (233), Expect = 4e-19
Identities = 75/243 (30%), Positives = 127/243 (52%), Gaps = 22/243 (9%)
Query: 539 ENLRRKEEAE---QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI 595
+ LR KE+AE +RQ E++RRR E EER++K L A E + ++ +++
Sbjct: 1935 DTLRSKEQAELEAARQRQLAAEEERRRREA-----EERVQKSLAAEEEAARQRKAALEEV 1989
Query: 596 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 655
E+ A+++E + ER +E A++ A +E +R Q EE +QQ+E+E
Sbjct: 1990 ERLKAKVEEA--RRLRERAEQESARQLQLA---QEAAQKRLQAEEKAHAFAVQQKEQEL- 2043
Query: 656 HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQ----ERREQERREQ 711
Q+ LQ+++ + +A A+R AE+ E+ R + ER + R Q ER +Q EQ
Sbjct: 2044 -QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2102
Query: 712 ERQLAEQERRREQERLQAERELQER---EKALRLQKEQLQRELEEKKKKEEQQRLAERQL 768
+ A+ + E+ R +AE+E R E+A QK+ E+E+ KK EQ + Q+
Sbjct: 2103 AQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2162
Query: 769 QEE 771
++E
Sbjct: 2163 EQE 2165
Score = 93.6 bits (231), Expect = 8e-19
Identities = 87/327 (26%), Positives = 161/327 (49%), Gaps = 29/327 (8%)
Query: 531 KEKERQRLENLRRKEEA--EQLRRQKVEEDKRRRL---EEVKLKREERLRKVLQARERVE 585
+ KE+ LE R+++ A E+ RR++ EE ++ L EE +R+ L +V + + +VE
Sbjct: 1938 RSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE 1997
Query: 586 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE------ 639
+ + +++ ++ Q+ E A++ AEEKA A +K +E++ +QE+
Sbjct: 1998 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2057
Query: 640 --EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 697
EA R +E EE R +Q ++E Q R R+ EA+RL +Q +E+ + + Q
Sbjct: 2058 RGEAEAARRAAEEAEEAR----VQAEREAAQSR-RQVEEAERL-KQSAEEQAQARAQAQA 2111
Query: 698 RREQERREQERREQERQLAEQERRREQERLQAERELQER--EKALRLQKEQLQRELEEKK 755
E+ R+E E+ R AEQ R+++ AE E ++ E+ LR QK Q+++EL +
Sbjct: 2112 AAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR-QKAQVEQELTTLR 2170
Query: 756 KKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKINP 815
+ E+ + L EE ++ EA A++ + V+ + + + +I
Sbjct: 2171 LQLEETDHQKNLLDEELQRLKAEATEAARQRS---QVEEELFSVRVQMEELSKLKARIEA 2227
Query: 816 DNYGMDLNSDDST----DDEAHPRKPI 838
+N + L D+T +EA K +
Sbjct: 2228 ENRALILRDKDNTQRFLQEEAEKMKQV 2254
Score = 89.0 bits (219), Expect = 2e-17
Identities = 77/277 (27%), Positives = 135/277 (48%), Gaps = 18/277 (6%)
Query: 513 RSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE 572
R + ++ + + KE +++ E + R+EEA ++ KR EE++ R+
Sbjct: 1351 RQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV----DAQQQKRSIQEELQQLRQS 1406
Query: 573 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 632
++ QA+ R + E + +IE++ + + E + +R E + +A + EE E
Sbjct: 1407 SEAEI-QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAE-GELQALRARAEEAE 1464
Query: 633 A--RRKQEEEARRLRWLQQEEEERRHQ---ELLQKKKEE-----EQERLRKAAEAKRLAE 682
A R+ Q EEA RLR Q+E +R+ Q EL + K E E++R +A E RL
Sbjct: 1465 AQKRQAQ-EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQA 1523
Query: 683 QREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRL 742
+ + R Q E+ R+ Q E +R E +L + ++ Q ER LQE A+
Sbjct: 1524 EEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ 1583
Query: 743 QKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 779
+E+ +R +++ + E + AER+L E + KA EA
Sbjct: 1584 LREEAERRAQQQAEAERAREEAEREL-ERWQLKANEA 1619
Score = 87.4 bits (215), Expect = 5e-17
Identities = 138/560 (24%), Positives = 235/560 (41%), Gaps = 117/560 (20%)
Query: 316 QVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQ 375
Q L Q+ S++ + A+RR A++ E + R S R E + S +
Sbjct: 2045 QTLQQEQSVLDQLRGEAE-AARRAAEEAEEARVQAEREAAQS---RRQVEEAERLKQSAE 2100
Query: 376 KEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTD 435
++ A+ AAAE E + E A + A + A ++ K
Sbjct: 2101 EQAQARAQAQAAAEKLRKEA---------EQEAARRAQAEQAALRQKQAADAEMEKHKKF 2151
Query: 436 QADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTF 495
R+ Q + + + + E D +++L DEELQ +++ + S+V L +
Sbjct: 2152 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2211
Query: 496 LHTVQRNQMLMTPTSAPRSVMKSFIKRNTP-LRMDPKEKERQRLENLRR----KEEAEQL 550
++ L A + K NT + EK +Q E R +EA +L
Sbjct: 2212 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2271
Query: 551 RRQKVEED--KRRRLEEVKLKREERLRKVLQAR------ERVEQMKE----------EKK 592
R Q EED ++R L E LK E+++ V +A E ++Q KE E K
Sbjct: 2272 R-QLAEEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK 2328
Query: 593 KQIEQKFAQIDE---KTEKAKEERLAEEKAKKKAAAKKMEEVE-ARRKQEEEARRLRWLQ 648
+Q+ Q+ A+ + +T +A+ +R E A+ + ++ E+ A+ + EE+A+R R
Sbjct: 2329 EQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQA 2388
Query: 649 QEEEERRHQ---------------ELLQKKKEEEQERLRKA-AEAKRLAEQREQERR--- 689
+E E+ H+ E+ +++ + + ERLR+A AE +R E+ +QE +
Sbjct: 2389 EEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2448
Query: 690 ---------------------------------------EQERREQER-------REQER 703
EQE+ + E+ + Q+
Sbjct: 2449 LKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL 2508
Query: 704 REQERREQERQLAEQERRR------EQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
RE+++R+Q++ EQER+R E R Q E E R K LQ+ + QR +E+
Sbjct: 2509 REEQQRQQQQM--EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLA 2566
Query: 758 EEQQRLAER-QLQEEQEKKA 776
EE QRL E+ QL EEQ + A
Sbjct: 2567 EENQRLREQLQLLEEQHRAA 2586
Score = 86.7 bits (213), Expect = 9e-17
Identities = 98/403 (24%), Positives = 185/403 (45%), Gaps = 53/403 (13%)
Query: 445 QSARRKRSYKQAVSELDEEQHLED--------EELQPPRSKTPSSPCPASKVVRPLRTFL 496
Q ARR++ QA+ D + E EE++ K A + + ++ +
Sbjct: 1202 QDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYE 1261
Query: 497 HTVQRNQMLMTPTSAP------RSVMKSFIKRNTPLRMDPKEKERQRL-------ENLRR 543
+ + + P ++P +S +S I+ LR E E LRR
Sbjct: 1262 LQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRR 1321
Query: 544 KEEAEQLRRQKVEEDKRRRLE-EVKLKREERLRKV-LQARERVEQMKEEKKKQIEQKFAQ 601
EE E+L Q+ E++ R E E L+++ +L + QA+ + E+ +E +++++++ +
Sbjct: 1322 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1381
Query: 602 IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQ 661
+E A++++ + ++ ++ E++A+ +Q E A R R L+ EEE R +
Sbjct: 1382 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR-LRIEEEIR-----VV 1435
Query: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 721
+ + E ER R AE E + R +E Q+R+ QE E+ RR Q+ ++ +R
Sbjct: 1436 RLQLEATERQRGGAEG----ELQALRARAEEAEAQKRQAQEEAERLRR----QVQDESQR 1487
Query: 722 REQ------ERLQAERE-LQEREKA------LRLQKEQLQREL---EEKKKKEEQQRLAE 765
+ Q R++AE E +E+++A LRLQ E+ +R L E ++ ++ Q L
Sbjct: 1488 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALET 1547
Query: 766 RQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHR 808
Q E E ++K A+ A K + +Q Q+ + R
Sbjct: 1548 AQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER 1590
Score = 86.7 bits (213), Expect = 9e-17
Identities = 120/544 (22%), Positives = 218/544 (40%), Gaps = 79/544 (14%)
Query: 299 DSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSY 358
+SQ R + + +S +V A+ + KQ ++ RL + AE R + +
Sbjct: 1484 ESQRKRQAEVELAS---RVKAEAEAAREKQRALQALEELRLQAEEAE------RRLRQAE 1534
Query: 359 LERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPA 418
+ER V+V + E +++ + AE S +A +
Sbjct: 1535 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER---SLQEEHVAVAQLREEAERR 1591
Query: 419 ASSPETPSAGQQEA---------KTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDE 469
A ++EA K ++A R + +++S QA +E +E E E
Sbjct: 1592 AQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKE---EAE 1648
Query: 470 ELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMD 529
R K + VR +++ + L T+ R + + R LR +
Sbjct: 1649 REARRRGKAEE------QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR---LRAE 1699
Query: 530 PKEKERQR------LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER 583
++ E+QR L L+R+ A +RQ++E + L +V+ + E L +A E
Sbjct: 1700 TEQGEQQRQLLEEELARLQREAAAATQKRQELEAE----LAKVRAEMEVLLASKARAEEE 1755
Query: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE--- 640
E+ K+++E + + E E+A R E+AK++ + EE AR++ E E
Sbjct: 1756 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQR--QLAEEDAARQRAEAERVL 1813
Query: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
A +L + + + E+ K+KE E ERLR+ AE + +R +E+ Q + + E R
Sbjct: 1814 AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL 1873
Query: 701 QERREQERREQERQLA------EQERRREQE-------------------------RLQA 729
+ R+ E ERQ Q R+ E+E R A
Sbjct: 1874 AQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA 1933
Query: 730 ERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVT 789
E L+ +E+A Q Q EE++++ E + ++ L E+E + A + +
Sbjct: 1934 EDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLK 1993
Query: 790 VDVQ 793
V+
Sbjct: 1994 AKVE 1997
Score = 82.8 bits (203), Expect = 1e-15
Identities = 119/525 (22%), Positives = 224/525 (42%), Gaps = 92/525 (17%)
Query: 319 AQKYSLVAKQESVVRRASRRLAKK-TAEEPAASGRIICHSYLERLL-------------- 363
A++ L A++E R A R+ K AEE AA R +ERL
Sbjct: 1948 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2007
Query: 364 -----NVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPA 418
+++ Q+ ++ + E+A A + E + + + + A
Sbjct: 2008 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE---QELQQTLQQEQSVLDQLRGEAEAA 2064
Query: 419 ASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKT 478
+ E + +A+ + A R+ ++ R K+S ++ + Q ++ + +
Sbjct: 2065 RRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2124
Query: 479 PSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRL 538
+R + +++++ T ++ ++ + T LR+ +E + Q+
Sbjct: 2125 ARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQEL---TTLRLQLEETDHQKN 2181
Query: 539 ---ENLRR-KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 594
E L+R K EA + RQ+ + ++ V+++ +L+ ++A R +++ K
Sbjct: 2182 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD---KD 2238
Query: 595 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 654
Q+F Q E+ EK K+ +AEE A+ AA +EA RLR L +E+ +
Sbjct: 2239 NTQRFLQ--EEAEKMKQ--VAEEAARLSVAA-------------QEAARLRQLAEEDLAQ 2281
Query: 655 RH---QELLQKKKEEEQERLRKAAEAKRLAEQR----EQERREQERREQERRE------- 700
+ +++L++K + QE R AEA+ L +Q+ EQ RR QE +EQ ++
Sbjct: 2282 QRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2341
Query: 701 -QERREQERREQERQLAEQER-------------RREQE----RLQAER--------ELQ 734
Q E ER+ Q AE ER R E++ R QAE EL
Sbjct: 2342 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2401
Query: 735 EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 779
+EK +Q ++QR+ + + ++ +AE L+ E+EK +EA
Sbjct: 2402 TQEKVTLVQTLEIQRQQSDHDAERLREAIAE--LEREKEKLQQEA 2444
Score = 75.1 bits (183), Expect = 3e-13
Identities = 70/275 (25%), Positives = 129/275 (46%), Gaps = 16/275 (5%)
Query: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL--KREERLRKVLQARERVEQMKE 589
E ERQR + + E +LR ++ + R E+ + K+ E + + L E Q K
Sbjct: 2347 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKV 2406
Query: 590 EKKKQIEQKFAQIDEKTEKAKEE--RLAEEKAKKKAAAK--KMEEVEARRKQEEEARRLR 645
+ +E + Q D E+ +E L EK K + AK +++ E + Q+E+ +
Sbjct: 2407 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQET 2466
Query: 646 WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR- 704
Q+ LLQ+++ EQE+ + + + +Q R EQ+R++Q+ ++ +R
Sbjct: 2467 QALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRL 2526
Query: 705 ---EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 761
+E R ++ + E RR+++E Q E++ +++E+ L E+ QR E+ + EEQ
Sbjct: 2527 VASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL---AEENQRLREQLQLLEEQH 2583
Query: 762 RLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPA 796
R A L +E A + A N + PA
Sbjct: 2584 RAA---LAHSEEVTASQVAATKTLPNGRDALDGPA 2615
Score = 65.5 bits (158), Expect = 2e-10
Identities = 80/345 (23%), Positives = 153/345 (44%), Gaps = 46/345 (13%)
Query: 433 KTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPL 492
+T +A+ R+ SA +R K V+E+ Q +E+ Q R + A ++ L
Sbjct: 2344 RTLEAERQRQLEMSAEAER-LKLRVAEMSRAQARAEEDAQRFRKQ-------AEEIGEKL 2395
Query: 493 -RTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLR 551
RT L T ++ ++ T ++ + + +RL + E E+ +
Sbjct: 2396 HRTELATQEKVTLVQT----------------LEIQRQQSDHDAERLREAIAELEREKEK 2439
Query: 552 RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 611
Q+ + + + EE++ ++E+L LQ + ++Q +K + Q+ I++ EKAK
Sbjct: 2440 LQQEAKLLQLKSEEMQTVQQEQL---LQETQALQQSFLSEKDSLLQRERFIEQ--EKAKL 2494
Query: 612 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERL 671
E+L +++ K A+++ E + R++Q+ E R R + EE RR Q ++ +QE L
Sbjct: 2495 EQLFQDEVAK---AQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL 2551
Query: 672 RKAAEAKRLAEQREQERREQERREQERREQERRE-QERREQERQLAEQERRREQERLQAE 730
+Q EQ+RR+QE E ++ R + Q EQ R ++ A
Sbjct: 2552 ----------QQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAAT 2601
Query: 731 RELQEREKAL--RLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE 773
+ L AL + + + + ++K QRL E + +E
Sbjct: 2602 KTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEE 2646
Score = 47.4 bits (111), Expect = 6e-05
Identities = 61/278 (21%), Positives = 128/278 (46%), Gaps = 35/278 (12%)
Query: 541 LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR---KVLQARERVEQMKEEKKKQIEQ 597
+R + AE++ R E+ K + L E + K L+A+ +Q + + +
Sbjct: 1073 IRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELR 1132
Query: 598 KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA--------RRKQEEEARRLRWLQQ 649
++ E+ ++ ER E + ++ A+ +E +A +R+ E+ R+LR+ +
Sbjct: 1133 GAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYR- 1191
Query: 650 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR--EQERREQERREQERREQE 707
E + L ++ +EQ + A+++ + EQ QE+ E+ R E+ E+ +R +
Sbjct: 1192 ESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAK 1251
Query: 708 R-----REQERQLAEQERRRE-------QERLQ--AERELQE-------REKALRLQKEQ 746
+ ++ E QL + + E + ++Q +E +QE + L +
Sbjct: 1252 QYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQY 1311
Query: 747 LQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 784
++ E ++ EE++RLAE+Q EE+E+ A+ A K
Sbjct: 1312 IKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEK 1349
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 102 bits (253), Expect = 2e-21
Identities = 100/387 (25%), Positives = 182/387 (47%), Gaps = 34/387 (8%)
Query: 418 AASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSK 477
A + + + ++EAK Q R + RR+ + AV +++ +++E Q +S
Sbjct: 1362 AEAHAQAKAQAEREAKELQQ---RMQEEVVRREEA---AVDAQQQKRSIQEELQQLRQSS 1415
Query: 478 TPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQR 537
A + R+ L + +++ A LR +E E Q+
Sbjct: 1416 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1475
Query: 538 LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERL--------RKVLQARERVEQMKE 589
+ +EEAE+LRRQ +E +R+R EV+L + ++ LQA E + E
Sbjct: 1476 RQ---AQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE 1532
Query: 590 EKKKQIEQ----KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 645
E ++++ Q + Q+ E A+ AE ++K+ + A+K ++E R +EE +
Sbjct: 1533 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE--RSLQEEHVAVA 1590
Query: 646 WLQQEEEERRHQELLQKKKEEEQER-----LRKAAEAKRL---AEQREQERREQERREQE 697
L++E E R Q+ ++ EE ER KA EA RL AE+ Q++ + ++
Sbjct: 1591 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1650
Query: 698 RREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
++E+ RE RR + + A ++R ++ L+ +R+L E RL EQ L + ++
Sbjct: 1651 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQ 1710
Query: 758 EEQQRLAERQLQEEQEKKAKEAAGASK 784
EQQR + L+EE + +EAA A++
Sbjct: 1711 GEQQR---QLLEEELARLQREAAAATQ 1734
Score = 96.7 bits (239), Expect = 9e-20
Identities = 150/595 (25%), Positives = 258/595 (43%), Gaps = 118/595 (19%)
Query: 296 SRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAK-QESVVRRASRRL----AKKTAEEPAAS 350
+ + QS R S ++ + L +++ VA+ +E RRA ++ A++ AE
Sbjct: 1560 AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELER 1619
Query: 351 GRIICHSYLE-RLLNVEVPQKVG---SEQKEPPEEAEPVA-----AAEPEVPENNGNNSW 401
++ + L RL EV Q+ +E ++ EEAE A A E V +
Sbjct: 1620 WQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE 1679
Query: 402 PHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELD 461
++A T + AA + A+T+Q + R+ + R ++A +
Sbjct: 1680 LEKQRQLAEGTAQQRLAAEQELI----RLRAETEQGEQQRQLLEE-ELARLQREAAAATQ 1734
Query: 462 EEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIK 521
+ Q LE EL R++ ++ R+ T ++++ + A + +
Sbjct: 1735 KRQELE-AELAKVRAEMEVLLASKARAEEESRS---TSEKSKQRL---EAEAGRFRELAE 1787
Query: 522 RNTPLRMDPKEKERQRL----ENLRRKEEAEQLRRQKV----EEDKRRRLEEVKLKREE- 572
LR +E +RQR + R++ EAE++ +K+ E + + E+ LK +E
Sbjct: 1788 EAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEA 1847
Query: 573 ---RLRKVLQ----ARERVEQMKEEKKKQIEQKFAQI----DEKTEKAK----------- 610
RLR++ + R R+E+ + K IE++ AQ+ D + E+ K
Sbjct: 1848 ENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1907
Query: 611 ---EERLAEEKAKKKAAAKKME--------------EVEARRKQEEEARRLRWLQQEEEE 653
EE LA + + +KAAA K E + ++ + E EA R R L EEE
Sbjct: 1908 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1967
Query: 654 RRHQ--ELLQKK--KEEEQERLRKAA------------EAKRLAEQREQERREQ------ 691
RR + E +QK EEE R RKAA EA+RL E+ EQE Q
Sbjct: 1968 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2027
Query: 692 -----------------ERREQERREQERREQERREQERQLAEQERR----REQERLQAE 730
+++EQE ++ ++EQ +Q R AE RR E+ R+QAE
Sbjct: 2028 AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE 2087
Query: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKA 785
RE + + + + E+L++ EE+ + Q + A +L++E E++A A A +A
Sbjct: 2088 REAAQSRRQVE-EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQA 2141
Score = 94.4 bits (233), Expect = 4e-19
Identities = 75/243 (30%), Positives = 127/243 (52%), Gaps = 22/243 (9%)
Query: 539 ENLRRKEEAE---QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI 595
+ LR KE+AE +RQ E++RRR E EER++K L A E + ++ +++
Sbjct: 1943 DTLRSKEQAELEAARQRQLAAEEERRRREA-----EERVQKSLAAEEEAARQRKAALEEV 1997
Query: 596 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 655
E+ A+++E + ER +E A++ A +E +R Q EE +QQ+E+E
Sbjct: 1998 ERLKAKVEEA--RRLRERAEQESARQLQLA---QEAAQKRLQAEEKAHAFAVQQKEQEL- 2051
Query: 656 HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQ----ERREQERREQ 711
Q+ LQ+++ + +A A+R AE+ E+ R + ER + R Q ER +Q EQ
Sbjct: 2052 -QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2110
Query: 712 ERQLAEQERRREQERLQAERELQER---EKALRLQKEQLQRELEEKKKKEEQQRLAERQL 768
+ A+ + E+ R +AE+E R E+A QK+ E+E+ KK EQ + Q+
Sbjct: 2111 AQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2170
Query: 769 QEE 771
++E
Sbjct: 2171 EQE 2173
Score = 93.6 bits (231), Expect = 8e-19
Identities = 87/327 (26%), Positives = 161/327 (49%), Gaps = 29/327 (8%)
Query: 531 KEKERQRLENLRRKEEA--EQLRRQKVEEDKRRRL---EEVKLKREERLRKVLQARERVE 585
+ KE+ LE R+++ A E+ RR++ EE ++ L EE +R+ L +V + + +VE
Sbjct: 1946 RSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE 2005
Query: 586 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE------ 639
+ + +++ ++ Q+ E A++ AEEKA A +K +E++ +QE+
Sbjct: 2006 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2065
Query: 640 --EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 697
EA R +E EE R +Q ++E Q R R+ EA+RL +Q +E+ + + Q
Sbjct: 2066 RGEAEAARRAAEEAEEAR----VQAEREAAQSR-RQVEEAERL-KQSAEEQAQARAQAQA 2119
Query: 698 RREQERREQERREQERQLAEQERRREQERLQAERELQER--EKALRLQKEQLQRELEEKK 755
E+ R+E E+ R AEQ R+++ AE E ++ E+ LR QK Q+++EL +
Sbjct: 2120 AAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLR-QKAQVEQELTTLR 2178
Query: 756 KKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKINP 815
+ E+ + L EE ++ EA A++ + V+ + + + +I
Sbjct: 2179 LQLEETDHQKNLLDEELQRLKAEATEAARQRS---QVEEELFSVRVQMEELSKLKARIEA 2235
Query: 816 DNYGMDLNSDDST----DDEAHPRKPI 838
+N + L D+T +EA K +
Sbjct: 2236 ENRALILRDKDNTQRFLQEEAEKMKQV 2262
Score = 89.0 bits (219), Expect = 2e-17
Identities = 77/277 (27%), Positives = 135/277 (48%), Gaps = 18/277 (6%)
Query: 513 RSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE 572
R + ++ + + KE +++ E + R+EEA ++ KR EE++ R+
Sbjct: 1359 RQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV----DAQQQKRSIQEELQQLRQS 1414
Query: 573 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 632
++ QA+ R + E + +IE++ + + E + +R E + +A + EE E
Sbjct: 1415 SEAEI-QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAE-GELQALRARAEEAE 1472
Query: 633 A--RRKQEEEARRLRWLQQEEEERRHQ---ELLQKKKEE-----EQERLRKAAEAKRLAE 682
A R+ Q EEA RLR Q+E +R+ Q EL + K E E++R +A E RL
Sbjct: 1473 AQKRQAQ-EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQA 1531
Query: 683 QREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRL 742
+ + R Q E+ R+ Q E +R E +L + ++ Q ER LQE A+
Sbjct: 1532 EEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ 1591
Query: 743 QKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 779
+E+ +R +++ + E + AER+L E + KA EA
Sbjct: 1592 LREEAERRAQQQAEAERAREEAEREL-ERWQLKANEA 1627
Score = 87.4 bits (215), Expect = 5e-17
Identities = 138/560 (24%), Positives = 235/560 (41%), Gaps = 117/560 (20%)
Query: 316 QVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQ 375
Q L Q+ S++ + A+RR A++ E + R S R E + S +
Sbjct: 2053 QTLQQEQSVLDQLRGEAE-AARRAAEEAEEARVQAEREAAQS---RRQVEEAERLKQSAE 2108
Query: 376 KEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTD 435
++ A+ AAAE E + E A + A + A ++ K
Sbjct: 2109 EQAQARAQAQAAAEKLRKEA---------EQEAARRAQAEQAALRQKQAADAEMEKHKKF 2159
Query: 436 QADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTF 495
R+ Q + + + + E D +++L DEELQ +++ + S+V L +
Sbjct: 2160 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2219
Query: 496 LHTVQRNQMLMTPTSAPRSVMKSFIKRNTP-LRMDPKEKERQRLENLRR----KEEAEQL 550
++ L A + K NT + EK +Q E R +EA +L
Sbjct: 2220 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2279
Query: 551 RRQKVEED--KRRRLEEVKLKREERLRKVLQAR------ERVEQMKE----------EKK 592
R Q EED ++R L E LK E+++ V +A E ++Q KE E K
Sbjct: 2280 R-QLAEEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK 2336
Query: 593 KQIEQKFAQIDE---KTEKAKEERLAEEKAKKKAAAKKMEEVE-ARRKQEEEARRLRWLQ 648
+Q+ Q+ A+ + +T +A+ +R E A+ + ++ E+ A+ + EE+A+R R
Sbjct: 2337 EQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQA 2396
Query: 649 QEEEERRHQ---------------ELLQKKKEEEQERLRKA-AEAKRLAEQREQERR--- 689
+E E+ H+ E+ +++ + + ERLR+A AE +R E+ +QE +
Sbjct: 2397 EEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2456
Query: 690 ---------------------------------------EQERREQER-------REQER 703
EQE+ + E+ + Q+
Sbjct: 2457 LKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL 2516
Query: 704 REQERREQERQLAEQERRR------EQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
RE+++R+Q++ EQER+R E R Q E E R K LQ+ + QR +E+
Sbjct: 2517 REEQQRQQQQM--EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLA 2574
Query: 758 EEQQRLAER-QLQEEQEKKA 776
EE QRL E+ QL EEQ + A
Sbjct: 2575 EENQRLREQLQLLEEQHRAA 2594
Score = 86.7 bits (213), Expect = 9e-17
Identities = 98/403 (24%), Positives = 185/403 (45%), Gaps = 53/403 (13%)
Query: 445 QSARRKRSYKQAVSELDEEQHLED--------EELQPPRSKTPSSPCPASKVVRPLRTFL 496
Q ARR++ QA+ D + E EE++ K A + + ++ +
Sbjct: 1210 QDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYE 1269
Query: 497 HTVQRNQMLMTPTSAP------RSVMKSFIKRNTPLRMDPKEKERQRL-------ENLRR 543
+ + + P ++P +S +S I+ LR E E LRR
Sbjct: 1270 LQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRR 1329
Query: 544 KEEAEQLRRQKVEEDKRRRLE-EVKLKREERLRKV-LQARERVEQMKEEKKKQIEQKFAQ 601
EE E+L Q+ E++ R E E L+++ +L + QA+ + E+ +E +++++++ +
Sbjct: 1330 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVR 1389
Query: 602 IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQ 661
+E A++++ + ++ ++ E++A+ +Q E A R R L+ EEE R +
Sbjct: 1390 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR-LRIEEEIR-----VV 1443
Query: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 721
+ + E ER R AE E + R +E Q+R+ QE E+ RR Q+ ++ +R
Sbjct: 1444 RLQLEATERQRGGAEG----ELQALRARAEEAEAQKRQAQEEAERLRR----QVQDESQR 1495
Query: 722 REQ------ERLQAERE-LQEREKA------LRLQKEQLQREL---EEKKKKEEQQRLAE 765
+ Q R++AE E +E+++A LRLQ E+ +R L E ++ ++ Q L
Sbjct: 1496 KRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALET 1555
Query: 766 RQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHR 808
Q E E ++K A+ A K + +Q Q+ + R
Sbjct: 1556 AQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER 1598
Score = 86.7 bits (213), Expect = 9e-17
Identities = 120/544 (22%), Positives = 218/544 (40%), Gaps = 79/544 (14%)
Query: 299 DSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSY 358
+SQ R + + +S +V A+ + KQ ++ RL + AE R + +
Sbjct: 1492 ESQRKRQAEVELAS---RVKAEAEAAREKQRALQALEELRLQAEEAE------RRLRQAE 1542
Query: 359 LERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPA 418
+ER V+V + E +++ + AE S +A +
Sbjct: 1543 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER---SLQEEHVAVAQLREEAERR 1599
Query: 419 ASSPETPSAGQQEA---------KTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDE 469
A ++EA K ++A R + +++S QA +E +E E E
Sbjct: 1600 AQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKE---EAE 1656
Query: 470 ELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMD 529
R K + VR +++ + L T+ R + + R LR +
Sbjct: 1657 REARRRGKAEE------QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR---LRAE 1707
Query: 530 PKEKERQR------LENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER 583
++ E+QR L L+R+ A +RQ++E + L +V+ + E L +A E
Sbjct: 1708 TEQGEQQRQLLEEELARLQREAAAATQKRQELEAE----LAKVRAEMEVLLASKARAEEE 1763
Query: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE--- 640
E+ K+++E + + E E+A R E+AK++ + EE AR++ E E
Sbjct: 1764 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQR--QLAEEDAARQRAEAERVL 1821
Query: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
A +L + + + E+ K+KE E ERLR+ AE + +R +E+ Q + + E R
Sbjct: 1822 AEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL 1881
Query: 701 QERREQERREQERQLA------EQERRREQE-------------------------RLQA 729
+ R+ E ERQ Q R+ E+E R A
Sbjct: 1882 AQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA 1941
Query: 730 ERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVT 789
E L+ +E+A Q Q EE++++ E + ++ L E+E + A + +
Sbjct: 1942 EDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLK 2001
Query: 790 VDVQ 793
V+
Sbjct: 2002 AKVE 2005
Score = 82.8 bits (203), Expect = 1e-15
Identities = 119/525 (22%), Positives = 224/525 (42%), Gaps = 92/525 (17%)
Query: 319 AQKYSLVAKQESVVRRASRRLAKK-TAEEPAASGRIICHSYLERLL-------------- 363
A++ L A++E R A R+ K AEE AA R +ERL
Sbjct: 1956 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2015
Query: 364 -----NVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPA 418
+++ Q+ ++ + E+A A + E + + + + A
Sbjct: 2016 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE---QELQQTLQQEQSVLDQLRGEAEAA 2072
Query: 419 ASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKT 478
+ E + +A+ + A R+ ++ R K+S ++ + Q ++ + +
Sbjct: 2073 RRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2132
Query: 479 PSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRL 538
+R + +++++ T ++ ++ + T LR+ +E + Q+
Sbjct: 2133 ARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQEL---TTLRLQLEETDHQKN 2189
Query: 539 ---ENLRR-KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 594
E L+R K EA + RQ+ + ++ V+++ +L+ ++A R +++ K
Sbjct: 2190 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD---KD 2246
Query: 595 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 654
Q+F Q E+ EK K+ +AEE A+ AA +EA RLR L +E+ +
Sbjct: 2247 NTQRFLQ--EEAEKMKQ--VAEEAARLSVAA-------------QEAARLRQLAEEDLAQ 2289
Query: 655 RH---QELLQKKKEEEQERLRKAAEAKRLAEQR----EQERREQERREQERRE------- 700
+ +++L++K + QE R AEA+ L +Q+ EQ RR QE +EQ ++
Sbjct: 2290 QRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG 2349
Query: 701 -QERREQERREQERQLAEQER-------------RREQE----RLQAER--------ELQ 734
Q E ER+ Q AE ER R E++ R QAE EL
Sbjct: 2350 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA 2409
Query: 735 EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 779
+EK +Q ++QR+ + + ++ +AE L+ E+EK +EA
Sbjct: 2410 TQEKVTLVQTLEIQRQQSDHDAERLREAIAE--LEREKEKLQQEA 2452
Score = 75.1 bits (183), Expect = 3e-13
Identities = 70/275 (25%), Positives = 129/275 (46%), Gaps = 16/275 (5%)
Query: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL--KREERLRKVLQARERVEQMKE 589
E ERQR + + E +LR ++ + R E+ + K+ E + + L E Q K
Sbjct: 2355 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKV 2414
Query: 590 EKKKQIEQKFAQIDEKTEKAKEE--RLAEEKAKKKAAAK--KMEEVEARRKQEEEARRLR 645
+ +E + Q D E+ +E L EK K + AK +++ E + Q+E+ +
Sbjct: 2415 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQET 2474
Query: 646 WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR- 704
Q+ LLQ+++ EQE+ + + + +Q R EQ+R++Q+ ++ +R
Sbjct: 2475 QALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRL 2534
Query: 705 ---EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 761
+E R ++ + E RR+++E Q E++ +++E+ L E+ QR E+ + EEQ
Sbjct: 2535 VASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL---AEENQRLREQLQLLEEQH 2591
Query: 762 RLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPA 796
R A L +E A + A N + PA
Sbjct: 2592 RAA---LAHSEEVTASQVAATKTLPNGRDALDGPA 2623
Score = 65.5 bits (158), Expect = 2e-10
Identities = 80/345 (23%), Positives = 153/345 (44%), Gaps = 46/345 (13%)
Query: 433 KTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPL 492
+T +A+ R+ SA +R K V+E+ Q +E+ Q R + A ++ L
Sbjct: 2352 RTLEAERQRQLEMSAEAER-LKLRVAEMSRAQARAEEDAQRFRKQ-------AEEIGEKL 2403
Query: 493 -RTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLR 551
RT L T ++ ++ T ++ + + +RL + E E+ +
Sbjct: 2404 HRTELATQEKVTLVQT----------------LEIQRQQSDHDAERLREAIAELEREKEK 2447
Query: 552 RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 611
Q+ + + + EE++ ++E+L LQ + ++Q +K + Q+ I++ EKAK
Sbjct: 2448 LQQEAKLLQLKSEEMQTVQQEQL---LQETQALQQSFLSEKDSLLQRERFIEQ--EKAKL 2502
Query: 612 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERL 671
E+L +++ K A+++ E + R++Q+ E R R + EE RR Q ++ +QE L
Sbjct: 2503 EQLFQDEVAK---AQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL 2559
Query: 672 RKAAEAKRLAEQREQERREQERREQERREQERRE-QERREQERQLAEQERRREQERLQAE 730
+Q EQ+RR+QE E ++ R + Q EQ R ++ A
Sbjct: 2560 ----------QQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAAT 2609
Query: 731 RELQEREKAL--RLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE 773
+ L AL + + + + ++K QRL E + +E
Sbjct: 2610 KTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEE 2654
Score = 47.4 bits (111), Expect = 6e-05
Identities = 61/278 (21%), Positives = 128/278 (46%), Gaps = 35/278 (12%)
Query: 541 LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR---KVLQARERVEQMKEEKKKQIEQ 597
+R + AE++ R E+ K + L E + K L+A+ +Q + + +
Sbjct: 1081 IRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELR 1140
Query: 598 KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA--------RRKQEEEARRLRWLQQ 649
++ E+ ++ ER E + ++ A+ +E +A +R+ E+ R+LR+ +
Sbjct: 1141 GAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYR- 1199
Query: 650 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR--EQERREQERREQERREQE 707
E + L ++ +EQ + A+++ + EQ QE+ E+ R E+ E+ +R +
Sbjct: 1200 ESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAK 1259
Query: 708 R-----REQERQLAEQERRRE-------QERLQ--AERELQE-------REKALRLQKEQ 746
+ ++ E QL + + E + ++Q +E +QE + L +
Sbjct: 1260 QYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQY 1319
Query: 747 LQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 784
++ E ++ EE++RLAE+Q EE+E+ A+ A K
Sbjct: 1320 IKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEK 1357
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.124 0.338
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,279,663
Number of Sequences: 37866
Number of extensions: 2382880
Number of successful extensions: 124185
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1676
Number of HSP's successfully gapped in prelim test: 1730
Number of HSP's that attempted gapping in prelim test: 18903
Number of HSP's gapped (non-prelim): 30019
length of query: 914
length of database: 18,247,518
effective HSP length: 111
effective length of query: 803
effective length of database: 14,044,392
effective search space: 11277646776
effective search space used: 11277646776
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.