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Search of human proteins with 10190698
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]
(321 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens] 650 0.0
gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens] 222 3e-58
gi|55953076 connexin 50 [Homo sapiens] 220 1e-57
gi|122939172 connexin 45 [Homo sapiens] 218 6e-57
gi|69122473 connexin 45 [Homo sapiens] 218 6e-57
gi|22779877 connexin 46 [Homo sapiens] 215 5e-56
gi|32483412 connexin 40 [Homo sapiens] 201 6e-52
gi|6631083 connexin 40 [Homo sapiens] 201 6e-52
gi|14211941 gap junction protein, alpha 10 [Homo sapiens] 196 2e-50
gi|62865885 connexin 37 [Homo sapiens] 192 4e-49
gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens] 190 1e-48
gi|4504001 connexin 43 [Homo sapiens] 184 1e-46
gi|159032020 gap junction protein, beta 6 [Homo sapiens] 153 2e-37
gi|158966714 gap junction protein, beta 6 [Homo sapiens] 153 2e-37
gi|158966717 gap junction protein, beta 6 [Homo sapiens] 153 2e-37
gi|40254837 gap junction protein, beta 6 [Homo sapiens] 153 2e-37
gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens] 140 2e-33
gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens] 130 1e-30
gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens] 113 2e-25
gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens] 113 2e-25
gi|42558283 gap junction protein beta 2 [Homo sapiens] 107 1e-23
gi|23397464 gap junction protein, beta 4 [Homo sapiens] 107 2e-23
gi|54607056 connexin 31 [Homo sapiens] 102 5e-22
gi|13128960 connexin 31 [Homo sapiens] 102 5e-22
gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens] 100 3e-21
gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens] 94 2e-19
gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens] 94 2e-19
gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens] 94 2e-19
gi|239508957 PREDICTED: similar to hCG1770601 [Homo sapiens] 94 2e-19
gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens] 94 2e-19
>gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]
Length = 321
Score = 650 bits (1677), Expect = 0.0
Identities = 321/321 (100%), Positives = 321/321 (100%)
Query: 1 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60
MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP
Sbjct: 1 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60
Query: 61 GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDP 120
GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDP
Sbjct: 61 GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDP 120
Query: 121 PESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSG 180
PESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSG
Sbjct: 121 PESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSG 180
Query: 181 LRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEV 240
LRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEV
Sbjct: 181 LRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEV 240
Query: 241 ECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRGAQAKRKSIYEIRNK 300
ECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRGAQAKRKSIYEIRNK
Sbjct: 241 ECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRGAQAKRKSIYEIRNK 300
Query: 301 DLPRVSVPNFGRTQSSDSAYV 321
DLPRVSVPNFGRTQSSDSAYV
Sbjct: 301 DLPRVSVPNFGRTQSSDSAYV 321
>gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]
Length = 439
Score = 222 bits (566), Expect = 3e-58
Identities = 125/299 (41%), Positives = 177/299 (59%), Gaps = 20/299 (6%)
Query: 4 WTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCN 63
W+ L RLLE + HST +G++ LTV+V+FRI++ A+ GE +Y DEQ F CNT QPGC+
Sbjct: 6 WSFLTRLLEE-IHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGCD 64
Query: 64 QACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAK--QRERRYSTVFLALDRD-- 119
CYD P+SH+R+WVFQI+++ TPS+ ++ Y+VH+ A+ ++ERR + R
Sbjct: 65 NVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGPRRAP 124
Query: 120 ----PPESIGGPGGTGGGGS----GGGKREDKKLQNAIVNGVLQNTENTSKE---TEPDC 168
PP G P G G G+ E+++ + G + E E T+
Sbjct: 125 RAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEE-ETGAAEGAGEEAEEAGAEEACTKAVG 183
Query: 169 LEVKEL-TPHPSGLRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPG 227
+ K TP P+G + R EG+ R Y+ Q+V R A E+ FLVGQY LYGF V
Sbjct: 184 ADGKAAGTPGPTGQHDGRRRIQR--EGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVRP 241
Query: 228 LYECNRYPCIKEVECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRG 286
+ C+R PC V+C+VSRPTEKTVFL+ M+ VS +C++LNL E+ HLG + AVRG
Sbjct: 242 FFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVRG 300
>gi|55953076 connexin 50 [Homo sapiens]
Length = 433
Score = 220 bits (560), Expect = 1e-57
Identities = 123/314 (39%), Positives = 176/314 (56%), Gaps = 50/314 (15%)
Query: 1 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60
MG+W+ L +LE V +HST+IGR+ LTV+ IFRILI+ E V+ DEQ+ FVCNT QP
Sbjct: 1 MGDWSFLGNILEE-VNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQP 59
Query: 61 GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDP 120
GC CYD AFPISHIR WV QII V TPSL ++ ++VH + E+R S
Sbjct: 60 GCENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHY-VRMEEKRKSR--------E 110
Query: 121 PESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSG 180
E +G GT GG G ++ + SK T+
Sbjct: 111 AEELGQQAGTNGGPDQGSVKK----------------SSGSKGTK--------------- 139
Query: 181 LRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEV 240
K R + + R YI ++F+ E+GF+VG YFLYGF + LY C+R+PC V
Sbjct: 140 -------KFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPLYRCSRWPCPNVV 192
Query: 241 ECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRGAQAKRKSIYEIRNK 300
+C+VSRPTEKT+F++FM +V+ + + LN+ EL HLG + I+ A++ + + + EI K
Sbjct: 193 DCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALK--RPVEQPLGEIPEK 250
Query: 301 DLPRVSVPNFGRTQ 314
L ++V + + +
Sbjct: 251 SLHSIAVSSIQKAK 264
>gi|122939172 connexin 45 [Homo sapiens]
Length = 396
Score = 218 bits (555), Expect = 6e-57
Identities = 107/278 (38%), Positives = 170/278 (61%), Gaps = 21/278 (7%)
Query: 4 WTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCN 63
W+ L RLLE + HST +G+I LTV+++FRI++ A+ GE++Y DEQ+ FVCNT QPGC
Sbjct: 3 WSFLTRLLEE-IHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCE 61
Query: 64 QACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDPPES 123
CYD P+SH+R+WVFQII+V TPS+ ++ Y++H+ AK + R P +
Sbjct: 62 NVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKM---EHGEADKKAARSKPYA 118
Query: 124 IGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSGLRT 183
+ + ED + + L++ + ++++P P G R
Sbjct: 119 MRWKQHRALEETEEDNEEDPMMYPEM---ELESDKENKEQSQP--------KPKHDGRRR 167
Query: 184 ASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEVECY 243
R++G+ + Y++Q++ R E+GFL+GQYFLYGF V Y C+R PC +++C+
Sbjct: 168 I------REDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCF 221
Query: 244 VSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIK 281
+SRPTEKT+FL+ M+ V+G+C++LN+ E+ HLG+ I+
Sbjct: 222 ISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIR 259
>gi|69122473 connexin 45 [Homo sapiens]
Length = 396
Score = 218 bits (555), Expect = 6e-57
Identities = 107/278 (38%), Positives = 170/278 (61%), Gaps = 21/278 (7%)
Query: 4 WTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCN 63
W+ L RLLE + HST +G+I LTV+++FRI++ A+ GE++Y DEQ+ FVCNT QPGC
Sbjct: 3 WSFLTRLLEE-IHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCE 61
Query: 64 QACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDPPES 123
CYD P+SH+R+WVFQII+V TPS+ ++ Y++H+ AK + R P +
Sbjct: 62 NVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKM---EHGEADKKAARSKPYA 118
Query: 124 IGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSGLRT 183
+ + ED + + L++ + ++++P P G R
Sbjct: 119 MRWKQHRALEETEEDNEEDPMMYPEM---ELESDKENKEQSQP--------KPKHDGRRR 167
Query: 184 ASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEVECY 243
R++G+ + Y++Q++ R E+GFL+GQYFLYGF V Y C+R PC +++C+
Sbjct: 168 I------REDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCF 221
Query: 244 VSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIK 281
+SRPTEKT+FL+ M+ V+G+C++LN+ E+ HLG+ I+
Sbjct: 222 ISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIR 259
>gi|22779877 connexin 46 [Homo sapiens]
Length = 435
Score = 215 bits (547), Expect = 5e-56
Identities = 112/284 (39%), Positives = 164/284 (57%), Gaps = 50/284 (17%)
Query: 1 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60
MG+W+ L RLLE A Q+HST+IG++ LTV+ IFRIL++ E V+ DEQ+ F CNT QP
Sbjct: 1 MGDWSFLGRLLENA-QEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQP 59
Query: 61 GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDP 120
GC CYDRAFPISHIR+W QII V TP+L ++ + +H + +++ +R+
Sbjct: 60 GCENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKK--------EREE 111
Query: 121 PESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSG 180
E + KRE + KE D +PS
Sbjct: 112 EEQL--------------KRESP----------------SPKEPPQD---------NPSS 132
Query: 181 LRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEV 240
+ ++R + R Y+ ++F+ E+GF+ GQYFLYGF + LY C+R+PC V
Sbjct: 133 --RDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKPLYRCDRWPCPNTV 190
Query: 241 ECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAV 284
+C++SRPTEKT+F++FM AV+ ++LN+ E+ HLGW+K+K V
Sbjct: 191 DCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGV 234
>gi|32483412 connexin 40 [Homo sapiens]
Length = 358
Score = 201 bits (512), Expect = 6e-52
Identities = 107/281 (38%), Positives = 156/281 (55%), Gaps = 46/281 (16%)
Query: 1 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60
MG+W+ L LE V +HST++G++ LTV+ IFR+L++ E+ + DEQ F C+T+QP
Sbjct: 1 MGDWSFLGNFLEE-VHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQP 59
Query: 61 GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDP 120
GC CYD+AFPISHIRYWV QII V TPSL ++ +++H Q +R+
Sbjct: 60 GCQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKL----------- 108
Query: 121 PESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSG 180
RE ++ + V G +++ E C E
Sbjct: 109 -------------------REAERAKE--VRGSGSYEYPVAEKAELSCWE---------- 137
Query: 181 LRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEV 240
++ Q + Y+ ++ R +E+GF+VGQYF+YG + L+ C R PC V
Sbjct: 138 ---EGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLTTLHVCRRSPCPHPV 194
Query: 241 ECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIK 281
CYVSRPTEK VF+VFM AV+ + ++L+LAEL HLGW+KI+
Sbjct: 195 NCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIR 235
>gi|6631083 connexin 40 [Homo sapiens]
Length = 358
Score = 201 bits (512), Expect = 6e-52
Identities = 107/281 (38%), Positives = 156/281 (55%), Gaps = 46/281 (16%)
Query: 1 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60
MG+W+ L LE V +HST++G++ LTV+ IFR+L++ E+ + DEQ F C+T+QP
Sbjct: 1 MGDWSFLGNFLEE-VHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQP 59
Query: 61 GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDP 120
GC CYD+AFPISHIRYWV QII V TPSL ++ +++H Q +R+
Sbjct: 60 GCQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKL----------- 108
Query: 121 PESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSG 180
RE ++ + V G +++ E C E
Sbjct: 109 -------------------REAERAKE--VRGSGSYEYPVAEKAELSCWE---------- 137
Query: 181 LRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEV 240
++ Q + Y+ ++ R +E+GF+VGQYF+YG + L+ C R PC V
Sbjct: 138 ---EGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLTTLHVCRRSPCPHPV 194
Query: 241 ECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIK 281
CYVSRPTEK VF+VFM AV+ + ++L+LAEL HLGW+KI+
Sbjct: 195 NCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIR 235
>gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
Length = 543
Score = 196 bits (498), Expect = 2e-50
Identities = 107/281 (38%), Positives = 165/281 (58%), Gaps = 44/281 (15%)
Query: 1 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60
MG+W +L +LE V HST++G+I LT++ IFR+L++ + E V+DDEQ+ F CNT QP
Sbjct: 1 MGDWNLLGGILEE-VHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQP 59
Query: 61 GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQ-SAKQRERRYSTVFLALDRD 119
GCN CYD AFPIS IR+WV QII V +PSL ++ +++++ A +++R+ L +
Sbjct: 60 GCNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQME 119
Query: 120 PPESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPS 179
P+ +R D++L+ L+ + K CL
Sbjct: 120 NPDL----------DLEEQQRIDRELRR------LEEQKRIHKVPLKGCL---------- 153
Query: 180 GLRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKE 239
LRT Y++ ++ R+ LE+GF++GQY LYGF + LY+C + PC
Sbjct: 154 -LRT---------------YVLHILTRSVLEVGFMIGQYILYGFQMHPLYKCTQPPCPNA 197
Query: 240 VECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKI 280
V+C+VSRPTEKT+F++FM +++ I ++LN+ E+ HLG RKI
Sbjct: 198 VDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKI 238
>gi|62865885 connexin 37 [Homo sapiens]
Length = 333
Score = 192 bits (487), Expect = 4e-49
Identities = 109/290 (37%), Positives = 160/290 (55%), Gaps = 44/290 (15%)
Query: 1 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60
MG+W LE+LL+ VQ+HST++G+I LTV+ IFRILI+ + GE+V+ DEQ+ F CNT QP
Sbjct: 1 MGDWGFLEKLLDQ-VQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQP 59
Query: 61 GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDP 120
GC CYD+AFPISHIRYWV Q + V TP+L ++ + ++ S
Sbjct: 60 GCTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLS------------------- 100
Query: 121 PESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSG 180
+RE++ Q G L+ + E V+ +
Sbjct: 101 ------------------RREERLRQK---EGELRALPAKDPQVERALAAVER---QMAK 136
Query: 181 LRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEV 240
+ A +LR + + Y+ V+ ++ LE GFL GQ+ LYG+++ ++ C R PC V
Sbjct: 137 ISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWTMEPVFVCQRAPCPYLV 196
Query: 241 ECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRGAQAK 290
+C+VSRPTEKT+F++FM V I +VLNL EL HL R + +R Q +
Sbjct: 197 DCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGMRARQGQ 246
>gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
Length = 515
Score = 190 bits (483), Expect = 1e-48
Identities = 106/295 (35%), Positives = 173/295 (58%), Gaps = 48/295 (16%)
Query: 1 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60
MG+W +L LE V HSTMIG+I LT++ IFR+L++ + E V++DEQ+ F+CNT QP
Sbjct: 1 MGDWNLLGDTLEE-VHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQP 59
Query: 61 GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQ---SAKQRERRYSTVFLALD 117
GC CYD+AFPIS IRYWV Q+I V +PSL ++ +++++ ++R+R + + + L+
Sbjct: 60 GCRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELE 119
Query: 118 RDPPESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPH 177
E R+ ++L+ + LE ++L
Sbjct: 120 EVEFEM---------------PRDRRRLEQELCQ-----------------LEKRKL--- 144
Query: 178 PSGLRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCI 237
+K+ LR + Y+I + R+ +E+GF++GQY LYGF + L++C+ +PC
Sbjct: 145 -------NKAPLRGT--LLCTYVIHIFTRSVVEVGFMIGQYLLYGFHLEPLFKCHGHPCP 195
Query: 238 KEVECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRGAQAKRK 292
++C+VSRPTEKT+FL+FM +++ I + LN+ E+ HLG++KIK + G +K
Sbjct: 196 NIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKRGLWGKYKLKK 250
>gi|4504001 connexin 43 [Homo sapiens]
Length = 382
Score = 184 bits (466), Expect = 1e-46
Identities = 100/286 (34%), Positives = 167/286 (58%), Gaps = 44/286 (15%)
Query: 1 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60
MG+W+ L +LL+ VQ +ST G++ L+V+ IFRIL++ E+ + DEQ+ F CNT QP
Sbjct: 1 MGDWSALGKLLDK-VQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQP 59
Query: 61 GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDP 120
GC CYD++FPISH+R+WV QII V P+L ++ + + K+ +
Sbjct: 60 GCENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKL------------- 106
Query: 121 PESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSG 180
+++++L+ A +GV N + K+ +E+K+ G
Sbjct: 107 ------------------NKKEEELKVAQTDGV--NVDMHLKQ-----IEIKKF---KYG 138
Query: 181 LRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEV 240
+ K K+R G+ R YII ++F++ E+ FL+ Q+++YGFS+ +Y C R PC +V
Sbjct: 139 IEEHGKVKMR--GGLLRTYIISILFKSIFEVAFLLIQWYIYGFSLSAVYTCKRDPCPHQV 196
Query: 241 ECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRG 286
+C++SRPTEKT+F++FM VS + + LN+ EL ++ ++ +K V+G
Sbjct: 197 DCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRVKG 242
>gi|159032020 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 153 bits (386), Expect = 2e-37
Identities = 93/277 (33%), Positives = 134/277 (48%), Gaps = 69/277 (24%)
Query: 3 EWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGC 62
+W L + V +HST IG++ +TV+ IFR++I+ + + V+ DEQ FVCNTLQPGC
Sbjct: 2 DWGTLHTFI-GGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
Query: 63 NQACYDRAFPISHIRYWVFQIIMVCTPSL---CFITYSVHQSAKQRERRYSTVFLALDRD 119
CYD FP+SHIR W Q+I V TP+L + Y H++ ++ R
Sbjct: 61 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRR------------ 108
Query: 120 PPESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPS 179
G KR D K D ++K
Sbjct: 109 -----------------GEKRNDFK----------------------DIEDIK------- 122
Query: 180 GLRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLY-GFSVPGLYECNRYPCIK 238
K K+R + + Y + FR E F+ YFLY G+ +P + +C PC
Sbjct: 123 ------KQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPN 176
Query: 239 EVECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHL 275
V+C++SRPTEKTVF +FM + S IC++LN+AEL +L
Sbjct: 177 LVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYL 213
>gi|158966714 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 153 bits (386), Expect = 2e-37
Identities = 93/277 (33%), Positives = 134/277 (48%), Gaps = 69/277 (24%)
Query: 3 EWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGC 62
+W L + V +HST IG++ +TV+ IFR++I+ + + V+ DEQ FVCNTLQPGC
Sbjct: 2 DWGTLHTFI-GGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
Query: 63 NQACYDRAFPISHIRYWVFQIIMVCTPSL---CFITYSVHQSAKQRERRYSTVFLALDRD 119
CYD FP+SHIR W Q+I V TP+L + Y H++ ++ R
Sbjct: 61 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRR------------ 108
Query: 120 PPESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPS 179
G KR D K D ++K
Sbjct: 109 -----------------GEKRNDFK----------------------DIEDIK------- 122
Query: 180 GLRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLY-GFSVPGLYECNRYPCIK 238
K K+R + + Y + FR E F+ YFLY G+ +P + +C PC
Sbjct: 123 ------KQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPN 176
Query: 239 EVECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHL 275
V+C++SRPTEKTVF +FM + S IC++LN+AEL +L
Sbjct: 177 LVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYL 213
>gi|158966717 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 153 bits (386), Expect = 2e-37
Identities = 93/277 (33%), Positives = 134/277 (48%), Gaps = 69/277 (24%)
Query: 3 EWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGC 62
+W L + V +HST IG++ +TV+ IFR++I+ + + V+ DEQ FVCNTLQPGC
Sbjct: 2 DWGTLHTFI-GGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
Query: 63 NQACYDRAFPISHIRYWVFQIIMVCTPSL---CFITYSVHQSAKQRERRYSTVFLALDRD 119
CYD FP+SHIR W Q+I V TP+L + Y H++ ++ R
Sbjct: 61 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRR------------ 108
Query: 120 PPESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPS 179
G KR D K D ++K
Sbjct: 109 -----------------GEKRNDFK----------------------DIEDIK------- 122
Query: 180 GLRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLY-GFSVPGLYECNRYPCIK 238
K K+R + + Y + FR E F+ YFLY G+ +P + +C PC
Sbjct: 123 ------KQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPN 176
Query: 239 EVECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHL 275
V+C++SRPTEKTVF +FM + S IC++LN+AEL +L
Sbjct: 177 LVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYL 213
>gi|40254837 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 153 bits (386), Expect = 2e-37
Identities = 93/277 (33%), Positives = 134/277 (48%), Gaps = 69/277 (24%)
Query: 3 EWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGC 62
+W L + V +HST IG++ +TV+ IFR++I+ + + V+ DEQ FVCNTLQPGC
Sbjct: 2 DWGTLHTFI-GGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
Query: 63 NQACYDRAFPISHIRYWVFQIIMVCTPSL---CFITYSVHQSAKQRERRYSTVFLALDRD 119
CYD FP+SHIR W Q+I V TP+L + Y H++ ++ R
Sbjct: 61 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRR------------ 108
Query: 120 PPESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPS 179
G KR D K D ++K
Sbjct: 109 -----------------GEKRNDFK----------------------DIEDIK------- 122
Query: 180 GLRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLY-GFSVPGLYECNRYPCIK 238
K K+R + + Y + FR E F+ YFLY G+ +P + +C PC
Sbjct: 123 ------KQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPN 176
Query: 239 EVECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHL 275
V+C++SRPTEKTVF +FM + S IC++LN+AEL +L
Sbjct: 177 LVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYL 213
>gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]
Length = 279
Score = 140 bits (353), Expect = 2e-33
Identities = 94/279 (33%), Positives = 133/279 (47%), Gaps = 65/279 (23%)
Query: 7 LERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCNQAC 66
L RLL A + ST +GR+LL V++ FR++++A G VY DEQ+ FVC+T QPGC AC
Sbjct: 6 LRRLL-AEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAAC 64
Query: 67 YDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDPPESIGG 126
+D P+S +R+WVFQ+I+V PS ++ ++++ E
Sbjct: 65 FDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWEL------------------- 105
Query: 127 PGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSGLRTASK 186
SG GK E+ ++ G NT+ P LR
Sbjct: 106 --------SGKGKEEE-----TLIQGREGNTD----------------VPGAGSLR---- 132
Query: 187 SKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEVECYVSR 246
+ Y+ Q+ R LE L QY LYGF +P + C R PC+ + C +SR
Sbjct: 133 --------LLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFACRREPCLGSITCNLSR 184
Query: 247 PTEKTVFLVFMFAVSGICVVLNLAELNHLG----WRKIK 281
P+EKT+FL MF VSG C++ EL LG WR K
Sbjct: 185 PSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWK 223
>gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]
Length = 294
Score = 130 bits (328), Expect = 1e-30
Identities = 57/104 (54%), Positives = 79/104 (75%), Gaps = 1/104 (0%)
Query: 1 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60
MGEW L LL+A VQ S ++GR+ L V++IFRIL++A VG V++DEQ FVCNTLQP
Sbjct: 1 MGEWAFLGSLLDA-VQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQP 59
Query: 61 GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQ 104
GC Q CYDRAFP+SH R+W+F I+++ P + F+ YS+H++ K+
Sbjct: 60 GCRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKE 103
Score = 82.0 bits (201), Expect = 6e-16
Identities = 40/82 (48%), Positives = 53/82 (64%)
Query: 197 RFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEVECYVSRPTEKTVFLVF 256
R Y++ V R E+ FL GQ LYGF V + C PC V+C+VSRPTEKTVF++F
Sbjct: 134 RCYLLSVALRLLAELTFLGGQALLYGFRVAPHFACAGPPCPHTVDCFVSRPTEKTVFVLF 193
Query: 257 MFAVSGICVVLNLAELNHLGWR 278
FAV + +L++AEL HL W+
Sbjct: 194 YFAVGLLSALLSVAELGHLLWK 215
>gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 113 bits (283), Expect = 2e-25
Identities = 50/97 (51%), Positives = 70/97 (72%), Gaps = 1/97 (1%)
Query: 4 WTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCN 63
WT L LL + V +HST IGR+ L+V+ IFRI+++ + E+V+ DE++ F+CNTLQPGCN
Sbjct: 3 WTGLYTLL-SGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
Query: 64 QACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQ 100
CYD+ FPISH+R W Q+I+V TP+L + HQ
Sbjct: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQ 98
Score = 87.0 bits (214), Expect = 2e-17
Identities = 46/93 (49%), Positives = 62/93 (66%), Gaps = 4/93 (4%)
Query: 199 YIIQVVFRNALEIGFLVGQYFLY-GFSVPGLYECNRYPCIKEVECYVSRPTEKTVFLVFM 257
Y+I VVFR E F+ Y LY G+++ L +C+ YPC V+C+VSRPTEKTVF VFM
Sbjct: 135 YVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFM 194
Query: 258 FAVSGICVVLNLAELNHLGWRKIKLAVRGAQAK 290
A SGIC++LN+AE+ +L I+ R AQ +
Sbjct: 195 LAASGICIILNVAEVVYL---IIRACARRAQRR 224
>gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 113 bits (283), Expect = 2e-25
Identities = 50/97 (51%), Positives = 70/97 (72%), Gaps = 1/97 (1%)
Query: 4 WTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCN 63
WT L LL + V +HST IGR+ L+V+ IFRI+++ + E+V+ DE++ F+CNTLQPGCN
Sbjct: 3 WTGLYTLL-SGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
Query: 64 QACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQ 100
CYD+ FPISH+R W Q+I+V TP+L + HQ
Sbjct: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQ 98
Score = 87.0 bits (214), Expect = 2e-17
Identities = 46/93 (49%), Positives = 62/93 (66%), Gaps = 4/93 (4%)
Query: 199 YIIQVVFRNALEIGFLVGQYFLY-GFSVPGLYECNRYPCIKEVECYVSRPTEKTVFLVFM 257
Y+I VVFR E F+ Y LY G+++ L +C+ YPC V+C+VSRPTEKTVF VFM
Sbjct: 135 YVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFM 194
Query: 258 FAVSGICVVLNLAELNHLGWRKIKLAVRGAQAK 290
A SGIC++LN+AE+ +L I+ R AQ +
Sbjct: 195 LAASGICIILNVAEVVYL---IIRACARRAQRR 224
>gi|42558283 gap junction protein beta 2 [Homo sapiens]
Length = 226
Score = 107 bits (267), Expect = 1e-23
Identities = 51/106 (48%), Positives = 71/106 (66%), Gaps = 4/106 (3%)
Query: 3 EWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGC 62
+W L+ +L V +HST IG+I LTV+ IFRI+I+ + + V+ DEQ FVCNTLQPGC
Sbjct: 2 DWGTLQTIL-GGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGC 60
Query: 63 NQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERR 108
CYD FPISHIR W Q+I V TP+L ++H + ++ E++
Sbjct: 61 KNVCYDHYFPISHIRLWALQLIFVSTPAL---LVAMHVAYRRHEKK 103
Score = 85.1 bits (209), Expect = 8e-17
Identities = 43/89 (48%), Positives = 58/89 (65%), Gaps = 1/89 (1%)
Query: 188 KLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLY-GFSVPGLYECNRYPCIKEVECYVSR 246
K+R + + Y + FR E F+ Y +Y GFS+ L +CN +PC V+C+VSR
Sbjct: 125 KVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDCFVSR 184
Query: 247 PTEKTVFLVFMFAVSGICVVLNLAELNHL 275
PTEKTVF VFM AVSGIC++LN+ EL +L
Sbjct: 185 PTEKTVFTVFMIAVSGICILLNVTELCYL 213
>gi|23397464 gap junction protein, beta 4 [Homo sapiens]
Length = 266
Score = 107 bits (266), Expect = 2e-23
Identities = 47/103 (45%), Positives = 69/103 (66%), Gaps = 1/103 (0%)
Query: 4 WTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCN 63
W L+ LL + V ++ST++ RI L+VV IFR+L+ + E V+DDEQ FVCNT QPGC
Sbjct: 3 WAFLQGLL-SGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCP 61
Query: 64 QACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRE 106
CYD FP+SH+R W Q+I+V PSL + + ++ ++R+
Sbjct: 62 NVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERK 104
Score = 72.0 bits (175), Expect = 7e-13
Identities = 39/130 (30%), Positives = 72/130 (55%), Gaps = 2/130 (1%)
Query: 190 RRQEGISRFYIIQVVFRNALEIGFLVGQYFLY-GFSVPGLYECNRYPCIKEVECYVSRPT 248
+++ G+ Y++ ++F+ A++ GFL + LY + +P + C+ PC V+CY+SRPT
Sbjct: 122 KKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCYISRPT 181
Query: 249 EKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRGAQAKRKSIYEIRNKDLPRVSVP 308
EK VF FM + IC++LNL+E+ +L ++ + + G + +R E P +
Sbjct: 182 EKKVFTYFMVTTAAICILLNLSEVFYLVGKRC-MEIFGPRHRRPRCRECLPDTCPPYVLS 240
Query: 309 NFGRTQSSDS 318
G + +S
Sbjct: 241 QGGHPEDGNS 250
>gi|54607056 connexin 31 [Homo sapiens]
Length = 270
Score = 102 bits (254), Expect = 5e-22
Identities = 48/106 (45%), Positives = 66/106 (62%), Gaps = 1/106 (0%)
Query: 3 EWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGC 62
+W L+ LL + V ++ST GRI L+VV +FR+L+ + E V+ DEQ F CNT QPGC
Sbjct: 2 DWKTLQALL-SGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
Query: 63 NQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERR 108
CYD FPIS+IR W Q+I V PSL I + ++ ++R R
Sbjct: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHR 106
Score = 66.6 bits (161), Expect = 3e-11
Identities = 33/88 (37%), Positives = 54/88 (61%), Gaps = 2/88 (2%)
Query: 190 RRQEGISRFYIIQVVFRNALEIGFLVGQYFLY-GFSVPGLYEC-NRYPCIKEVECYVSRP 247
++ G+ Y+ ++F+ +E FL + L+ GF++P L +C N PC V+CY++RP
Sbjct: 122 KKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARP 181
Query: 248 TEKTVFLVFMFAVSGICVVLNLAELNHL 275
TEK +F FM S +C+VL + EL +L
Sbjct: 182 TEKKIFTYFMVGASAVCIVLTICELCYL 209
>gi|13128960 connexin 31 [Homo sapiens]
Length = 270
Score = 102 bits (254), Expect = 5e-22
Identities = 48/106 (45%), Positives = 66/106 (62%), Gaps = 1/106 (0%)
Query: 3 EWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGC 62
+W L+ LL + V ++ST GRI L+VV +FR+L+ + E V+ DEQ F CNT QPGC
Sbjct: 2 DWKTLQALL-SGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
Query: 63 NQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERR 108
CYD FPIS+IR W Q+I V PSL I + ++ ++R R
Sbjct: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHR 106
Score = 66.6 bits (161), Expect = 3e-11
Identities = 33/88 (37%), Positives = 54/88 (61%), Gaps = 2/88 (2%)
Query: 190 RRQEGISRFYIIQVVFRNALEIGFLVGQYFLY-GFSVPGLYEC-NRYPCIKEVECYVSRP 247
++ G+ Y+ ++F+ +E FL + L+ GF++P L +C N PC V+CY++RP
Sbjct: 122 KKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARP 181
Query: 248 TEKTVFLVFMFAVSGICVVLNLAELNHL 275
TEK +F FM S +C+VL + EL +L
Sbjct: 182 TEKKIFTYFMVGASAVCIVLTICELCYL 209
>gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]
Length = 273
Score = 99.8 bits (247), Expect = 3e-21
Identities = 43/105 (40%), Positives = 67/105 (63%), Gaps = 1/105 (0%)
Query: 4 WTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCN 63
W+I E LL + V ++ST GRI L++V IFR+L+ + E V+ D+ F CNT QPGC+
Sbjct: 3 WSIFEGLL-SGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCS 61
Query: 64 QACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERR 108
C+D FP+SH+R W Q+I+V PSL + + ++ +++ R
Sbjct: 62 NVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHR 106
Score = 70.5 bits (171), Expect = 2e-12
Identities = 37/103 (35%), Positives = 65/103 (63%), Gaps = 3/103 (2%)
Query: 190 RRQEGISRFYIIQVVFRNALEIGFL-VGQYFLYGFSVPGLYECNRYPCIKEVECYVSRPT 248
+++ G+ Y+ +VF+ +++I FL V F + +P + +C+ PC V+C++S+P+
Sbjct: 122 KKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDCFISKPS 181
Query: 249 EKTVFLVFMFAVSGICVVLNLAELNHLGWRKIK--LAVRGAQA 289
EK +F +FM A + IC++LNL EL +L ++ LA R AQA
Sbjct: 182 EKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQA 224
>gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 94.0 bits (232), Expect = 2e-19
Identities = 40/84 (47%), Positives = 61/84 (72%)
Query: 18 HSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCNQACYDRAFPISHIR 77
HST +GR+L V++ FR++++A G VY DEQ+ FVC+T QPGC AC+D P+S +R
Sbjct: 35 HSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFHPLSPLR 94
Query: 78 YWVFQIIMVCTPSLCFITYSVHQS 101
+WVFQ+I+V PS+ ++ Y+ +S
Sbjct: 95 FWVFQVILVAVPSVLYMGYTPWES 118
>gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 94.0 bits (232), Expect = 2e-19
Identities = 40/84 (47%), Positives = 61/84 (72%)
Query: 18 HSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCNQACYDRAFPISHIR 77
HST +GR+L V++ FR++++A G VY DEQ+ FVC+T QPGC AC+D P+S +R
Sbjct: 35 HSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFHPLSPLR 94
Query: 78 YWVFQIIMVCTPSLCFITYSVHQS 101
+WVFQ+I+V PS+ ++ Y+ +S
Sbjct: 95 FWVFQVILVAVPSVLYMGYTPWES 118
>gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 94.0 bits (232), Expect = 2e-19
Identities = 40/84 (47%), Positives = 61/84 (72%)
Query: 18 HSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCNQACYDRAFPISHIR 77
HST +GR+L V++ FR++++A G VY DEQ+ FVC+T QPGC AC+D P+S +R
Sbjct: 35 HSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFHPLSPLR 94
Query: 78 YWVFQIIMVCTPSLCFITYSVHQS 101
+WVFQ+I+V PS+ ++ Y+ +S
Sbjct: 95 FWVFQVILVAVPSVLYMGYTPWES 118
>gi|239508957 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 94.0 bits (232), Expect = 2e-19
Identities = 40/84 (47%), Positives = 61/84 (72%)
Query: 18 HSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCNQACYDRAFPISHIR 77
HST +GR+L V++ FR++++A G VY DEQ+ FVC+T QPGC AC+D P+S +R
Sbjct: 35 HSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFHPLSPLR 94
Query: 78 YWVFQIIMVCTPSLCFITYSVHQS 101
+WVFQ+I+V PS+ ++ Y+ +S
Sbjct: 95 FWVFQVILVAVPSVLYMGYTPWES 118
>gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]
Length = 223
Score = 94.0 bits (232), Expect = 2e-19
Identities = 44/105 (41%), Positives = 62/105 (59%), Gaps = 1/105 (0%)
Query: 4 WTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCN 63
W L LL + V ++ST G I L VV +FR+L+ + E V+ DEQ F CN+ QPGC
Sbjct: 3 WMFLRDLL-SGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGCK 61
Query: 64 QACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERR 108
C+D FPIS +R W Q+IMV TPSL + + + +++ R
Sbjct: 62 NVCFDDFFPISQVRLWALQLIMVSTPSLLVVLHVAYHEGREKRHR 106
Score = 82.8 bits (203), Expect = 4e-16
Identities = 39/83 (46%), Positives = 57/83 (68%), Gaps = 1/83 (1%)
Query: 194 GISRFYIIQVVFRNALEIGFLVGQYFLY-GFSVPGLYECNRYPCIKEVECYVSRPTEKTV 252
G+ Y+I ++ + EIGFLV Y LY GFSVP L +C+ PC V+C++S+PTEKT+
Sbjct: 119 GLWYAYLISLIVKTGFEIGFLVLFYKLYDGFSVPYLIKCDLKPCPNTVDCFISKPTEKTI 178
Query: 253 FLVFMFAVSGICVVLNLAELNHL 275
F++F+ S +C+VLN EL+ L
Sbjct: 179 FILFLVITSCLCIVLNFIELSFL 201
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,585,912
Number of Sequences: 37866
Number of extensions: 580999
Number of successful extensions: 6121
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 131
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 4642
Number of HSP's gapped (non-prelim): 1091
length of query: 321
length of database: 18,247,518
effective HSP length: 102
effective length of query: 219
effective length of database: 14,385,186
effective search space: 3150355734
effective search space used: 3150355734
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.