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Search of human proteins with 186910300
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|186910300 Rac GTPase activating protein 1 [Homo sapiens]
(632 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|186910302 Rac GTPase activating protein 1 [Homo sapiens] 1253 0.0
gi|186910300 Rac GTPase activating protein 1 [Homo sapiens] 1253 0.0
gi|21361397 Rac GTPase activating protein 1 [Homo sapiens] 1253 0.0
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 125 1e-28
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 122 1e-27
gi|194272142 myosin IXB isoform 2 [Homo sapiens] 118 2e-26
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 118 2e-26
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 114 3e-25
gi|91106928 beta chimerin isoform 1 [Homo sapiens] 114 3e-25
gi|229094128 active breakpoint cluster region-related protein i... 106 7e-23
gi|38679957 active breakpoint cluster region-related protein is... 106 7e-23
gi|38679954 active breakpoint cluster region-related protein is... 106 7e-23
gi|208022687 GTPase regulator associated with the focal adhesion... 102 1e-21
gi|7662208 GTPase regulator associated with the focal adhesion k... 102 1e-21
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens] 100 3e-21
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 100 7e-21
gi|156119615 myosin IXA [Homo sapiens] 99 2e-20
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 98 3e-20
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 98 3e-20
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 97 5e-20
gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo s... 95 2e-19
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 94 3e-19
gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens] 94 5e-19
gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens] 94 5e-19
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 93 8e-19
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa... 93 8e-19
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 93 8e-19
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 92 1e-18
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 92 1e-18
gi|4505507 oligophrenin 1 [Homo sapiens] 92 1e-18
>gi|186910302 Rac GTPase activating protein 1 [Homo sapiens]
Length = 632
Score = 1253 bits (3243), Expect = 0.0
Identities = 632/632 (100%), Positives = 632/632 (100%)
Query: 1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK 60
MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
Sbjct: 1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK 60
Query: 61 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE 120
AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
Sbjct: 61 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE 120
Query: 121 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR 180
QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
Sbjct: 121 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR 180
Query: 181 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP 240
EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
Sbjct: 181 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP 240
Query: 241 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC 300
YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
Sbjct: 241 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC 300
Query: 301 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP 360
VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
Sbjct: 301 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP 360
Query: 361 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS 420
MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
Sbjct: 361 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS 420
Query: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL 480
LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
Sbjct: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL 480
Query: 481 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS 540
QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
Sbjct: 481 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS 540
Query: 541 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS 600
QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
Sbjct: 541 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS 600
Query: 601 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK 632
TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
Sbjct: 601 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK 632
>gi|186910300 Rac GTPase activating protein 1 [Homo sapiens]
Length = 632
Score = 1253 bits (3243), Expect = 0.0
Identities = 632/632 (100%), Positives = 632/632 (100%)
Query: 1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK 60
MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
Sbjct: 1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK 60
Query: 61 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE 120
AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
Sbjct: 61 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE 120
Query: 121 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR 180
QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
Sbjct: 121 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR 180
Query: 181 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP 240
EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
Sbjct: 181 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP 240
Query: 241 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC 300
YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
Sbjct: 241 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC 300
Query: 301 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP 360
VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
Sbjct: 301 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP 360
Query: 361 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS 420
MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
Sbjct: 361 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS 420
Query: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL 480
LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
Sbjct: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL 480
Query: 481 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS 540
QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
Sbjct: 481 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS 540
Query: 541 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS 600
QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
Sbjct: 541 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS 600
Query: 601 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK 632
TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
Sbjct: 601 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK 632
>gi|21361397 Rac GTPase activating protein 1 [Homo sapiens]
Length = 632
Score = 1253 bits (3243), Expect = 0.0
Identities = 632/632 (100%), Positives = 632/632 (100%)
Query: 1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK 60
MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
Sbjct: 1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK 60
Query: 61 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE 120
AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
Sbjct: 61 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE 120
Query: 121 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR 180
QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
Sbjct: 121 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR 180
Query: 181 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP 240
EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
Sbjct: 181 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP 240
Query: 241 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC 300
YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
Sbjct: 241 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC 300
Query: 301 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP 360
VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
Sbjct: 301 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP 360
Query: 361 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS 420
MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
Sbjct: 361 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS 420
Query: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL 480
LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
Sbjct: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL 480
Query: 481 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS 540
QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
Sbjct: 481 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS 540
Query: 541 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS 600
QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
Sbjct: 541 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS 600
Query: 601 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK 632
TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
Sbjct: 601 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK 632
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 125 bits (314), Expect = 1e-28
Identities = 85/253 (33%), Positives = 129/253 (50%), Gaps = 9/253 (3%)
Query: 285 RLHDFVSKTVIKPESCVPCGKRIKFGKLS--LKCRDCRVVSHPECRDRCPLPCIPTLIGT 342
++H+F T P C C +G ++ +KC DC + H +C P C P L
Sbjct: 204 KIHNFKVHTFRGPHWCEYCAN-FMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHV 262
Query: 343 PVKIGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLR 402
K+ L V + P +V C+ EIE RGL GLYR+SG ++++K F R
Sbjct: 263 K-KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDR 321
Query: 403 --VKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQ 460
K ++ +DI+ I LK + R+L PL+T+ F+E+A+I D D + +++
Sbjct: 322 DGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHE 381
Query: 461 AVGELPQANRDTLAFLMIHLQRVA-QSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQ 519
A+ LP A+ +TL +LM HL+RV M+ NL VFGPT++ P D + L
Sbjct: 382 ALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRS--PELDAMAALN 439
Query: 520 DIKRQPKVVERLL 532
DI+ Q VVE L+
Sbjct: 440 DIRYQRLVVELLI 452
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 122 bits (305), Expect = 1e-27
Identities = 90/271 (33%), Positives = 132/271 (48%), Gaps = 15/271 (5%)
Query: 267 EPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESCVPCGKRIKFGKLS--LKCRDCRVVSH 324
E E DS G R+H F P C C +G ++ +KC DC + H
Sbjct: 166 ETHDERDSTGQ-DGVSEKRVHTFRG-----PHWCEYCAN-FMWGLIAQGVKCADCGLNVH 218
Query: 325 PECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLY 384
+C P C P L K+ L V + P +V C+ EIE RGL GLY
Sbjct: 219 KQCSKMVPNDCKPDLKHVK-KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLY 277
Query: 385 RISGCDRTVKELKEKFLR--VKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAF 442
R+SG ++++K F R K ++ +DI+ I LK + R+L PL+T+ F
Sbjct: 278 RVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKF 337
Query: 443 MEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVA-QSPHTKMDVANLAKVFG 501
+E+A+I D D + +++A+ LP A+ +TL +LM HL+RV M+ NL VFG
Sbjct: 338 IESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFG 397
Query: 502 PTIVAHAVPNPDPVTMLQDIKRQPKVVERLL 532
PT++ P D + L DI+ Q VVE L+
Sbjct: 398 PTLMRS--PELDAMAALNDIRYQRLVVELLI 426
>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
Length = 2022
Score = 118 bits (295), Expect = 2e-26
Identities = 85/279 (30%), Positives = 137/279 (49%), Gaps = 15/279 (5%)
Query: 287 HDFVSKTVIKPESCVPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTL--IGTP- 343
H F S V P+SC C I +L C C++ H +C + C T G P
Sbjct: 1633 HVFASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPG 1692
Query: 344 VKIGE-GMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLR 402
V+ G G+ D ++ +P ++ + +E GL GLYR SG +EL++
Sbjct: 1693 VEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQA--- 1749
Query: 403 VKTVPLLSKVDD--IHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQ 460
++T P K+++ IHAI +LK +LR L EPL+TF F+ A E+ ++ +AA+Y
Sbjct: 1750 LQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYA 1809
Query: 461 AVGELPQANRDTLAFLMIHLQRVA-QSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQ 519
+ LP+AN ++L L+ HL +VA +M LA +F P ++ N DP+T ++
Sbjct: 1810 VLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLL-RCPDNSDPLTSMK 1868
Query: 520 DIKRQPKVVERLLSLPLEYWSQFMMVEQENIDPLHVIEN 558
D+ + VE L+ + + V+ E I L E+
Sbjct: 1869 DVLKITTCVEMLIKEQMRKYK----VKMEEISQLEAAES 1903
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 118 bits (295), Expect = 2e-26
Identities = 85/279 (30%), Positives = 137/279 (49%), Gaps = 15/279 (5%)
Query: 287 HDFVSKTVIKPESCVPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTL--IGTP- 343
H F S V P+SC C I +L C C++ H +C + C T G P
Sbjct: 1633 HVFASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPG 1692
Query: 344 VKIGE-GMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLR 402
V+ G G+ D ++ +P ++ + +E GL GLYR SG +EL++
Sbjct: 1693 VEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQA--- 1749
Query: 403 VKTVPLLSKVDD--IHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQ 460
++T P K+++ IHAI +LK +LR L EPL+TF F+ A E+ ++ +AA+Y
Sbjct: 1750 LQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYA 1809
Query: 461 AVGELPQANRDTLAFLMIHLQRVA-QSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQ 519
+ LP+AN ++L L+ HL +VA +M LA +F P ++ N DP+T ++
Sbjct: 1810 VLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLL-RCPDNSDPLTSMK 1868
Query: 520 DIKRQPKVVERLLSLPLEYWSQFMMVEQENIDPLHVIEN 558
D+ + VE L+ + + V+ E I L E+
Sbjct: 1869 DVLKITTCVEMLIKEQMRKYK----VKMEEISQLEAAES 1903
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 114 bits (285), Expect = 3e-25
Identities = 79/253 (31%), Positives = 129/253 (50%), Gaps = 9/253 (3%)
Query: 285 RLHDFVSKTVIKPESCVPCGKRIKFGKLS--LKCRDCRVVSHPECRDRCPLPCIPTLIGT 342
+ H+F T P C C +G ++ ++C DC + H +C P C P L
Sbjct: 213 KTHNFKVHTFRGPHWCEYCAN-FMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRI 271
Query: 343 PVKIGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLR 402
K+ L V + P +V C+ EIE RGL GLYR+SG ++++K F R
Sbjct: 272 K-KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR 330
Query: 403 --VKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQ 460
K + DI+ I LK + R+L P++T+ F++AA+I++ D + A+++
Sbjct: 331 DGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHE 390
Query: 461 AVGELPQANRDTLAFLMIHLQRVAQSPHTK-MDVANLAKVFGPTIVAHAVPNPDPVTMLQ 519
+ LP A+ +TL +LMIHL++V + M+ NL VFGPT++ P +T L
Sbjct: 391 VLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLM--RPPEDSTLTTLH 448
Query: 520 DIKRQPKVVERLL 532
D++ Q +V+ L+
Sbjct: 449 DMRYQKLIVQILI 461
>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
Length = 332
Score = 114 bits (285), Expect = 3e-25
Identities = 79/253 (31%), Positives = 129/253 (50%), Gaps = 9/253 (3%)
Query: 285 RLHDFVSKTVIKPESCVPCGKRIKFGKLS--LKCRDCRVVSHPECRDRCPLPCIPTLIGT 342
+ H+F T P C C +G ++ ++C DC + H +C P C P L
Sbjct: 77 KTHNFKVHTFRGPHWCEYCAN-FMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRI 135
Query: 343 PVKIGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLR 402
K+ L V + P +V C+ EIE RGL GLYR+SG ++++K F R
Sbjct: 136 K-KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR 194
Query: 403 --VKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQ 460
K + DI+ I LK + R+L P++T+ F++AA+I++ D + A+++
Sbjct: 195 DGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHE 254
Query: 461 AVGELPQANRDTLAFLMIHLQRVAQSPHTK-MDVANLAKVFGPTIVAHAVPNPDPVTMLQ 519
+ LP A+ +TL +LMIHL++V + M+ NL VFGPT++ P +T L
Sbjct: 255 VLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLM--RPPEDSTLTTLH 312
Query: 520 DIKRQPKVVERLL 532
D++ Q +V+ L+
Sbjct: 313 DMRYQKLIVQILI 325
>gi|229094128 active breakpoint cluster region-related protein
isoform c [Homo sapiens]
Length = 813
Score = 106 bits (264), Expect = 7e-23
Identities = 64/146 (43%), Positives = 84/146 (57%), Gaps = 2/146 (1%)
Query: 362 IPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKF-LRVKTVPLLSKVDDIHAICS 420
+P IV CV E+E+RG+ E G+YRISG ++ LK F K + L+ DI+AI
Sbjct: 614 VPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAG 673
Query: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL 480
LK + R L EPLLT RL AFME ++D M + LP N T FL+ HL
Sbjct: 674 TLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHL 733
Query: 481 QRVAQ-SPHTKMDVANLAKVFGPTIV 505
+RVA+ P KM + NLA VFGPT++
Sbjct: 734 KRVAEKEPINKMSLHNLATVFGPTLL 759
>gi|38679957 active breakpoint cluster region-related protein
isoform a [Homo sapiens]
Length = 859
Score = 106 bits (264), Expect = 7e-23
Identities = 64/146 (43%), Positives = 84/146 (57%), Gaps = 2/146 (1%)
Query: 362 IPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKF-LRVKTVPLLSKVDDIHAICS 420
+P IV CV E+E+RG+ E G+YRISG ++ LK F K + L+ DI+AI
Sbjct: 660 VPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAG 719
Query: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL 480
LK + R L EPLLT RL AFME ++D M + LP N T FL+ HL
Sbjct: 720 TLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHL 779
Query: 481 QRVAQ-SPHTKMDVANLAKVFGPTIV 505
+RVA+ P KM + NLA VFGPT++
Sbjct: 780 KRVAEKEPINKMSLHNLATVFGPTLL 805
>gi|38679954 active breakpoint cluster region-related protein
isoform b [Homo sapiens]
Length = 822
Score = 106 bits (264), Expect = 7e-23
Identities = 64/146 (43%), Positives = 84/146 (57%), Gaps = 2/146 (1%)
Query: 362 IPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKF-LRVKTVPLLSKVDDIHAICS 420
+P IV CV E+E+RG+ E G+YRISG ++ LK F K + L+ DI+AI
Sbjct: 623 VPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAG 682
Query: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL 480
LK + R L EPLLT RL AFME ++D M + LP N T FL+ HL
Sbjct: 683 TLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHL 742
Query: 481 QRVAQ-SPHTKMDVANLAKVFGPTIV 505
+RVA+ P KM + NLA VFGPT++
Sbjct: 743 KRVAEKEPINKMSLHNLATVFGPTLL 768
>gi|208022687 GTPase regulator associated with the focal adhesion
kinase pp125 isoform b [Homo sapiens]
Length = 759
Score = 102 bits (254), Expect = 1e-21
Identities = 63/175 (36%), Positives = 100/175 (57%), Gaps = 10/175 (5%)
Query: 364 SIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVD-----DIHAI 418
SI+ C++ +E RG+ E GLYRI G + V++L + KT ++ D +I I
Sbjct: 391 SIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASE-TETDICAEWEIKTI 449
Query: 419 CSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMI 478
S LK +LR L PL+ ++ R+F++AA++ ++++ ++ ++ V LP+ NR L LM
Sbjct: 450 TSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMN 509
Query: 479 HLQRVAQS-PHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLL 532
HL VA + M VANL VFGPT++ P + V + DIK Q V+E L+
Sbjct: 510 HLANVANNHKQNLMTVANLGVVFGPTLLR---PQEETVAAIMDIKFQNIVIEILI 561
>gi|7662208 GTPase regulator associated with the focal adhesion
kinase pp125 isoform a [Homo sapiens]
Length = 814
Score = 102 bits (254), Expect = 1e-21
Identities = 63/175 (36%), Positives = 100/175 (57%), Gaps = 10/175 (5%)
Query: 364 SIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVD-----DIHAI 418
SI+ C++ +E RG+ E GLYRI G + V++L + KT ++ D +I I
Sbjct: 391 SIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASE-TETDICAEWEIKTI 449
Query: 419 CSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMI 478
S LK +LR L PL+ ++ R+F++AA++ ++++ ++ ++ V LP+ NR L LM
Sbjct: 450 TSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMN 509
Query: 479 HLQRVAQS-PHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLL 532
HL VA + M VANL VFGPT++ P + V + DIK Q V+E L+
Sbjct: 510 HLANVANNHKQNLMTVANLGVVFGPTLLR---PQEETVAAIMDIKFQNIVIEILI 561
>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
Length = 786
Score = 100 bits (250), Expect = 3e-21
Identities = 65/182 (35%), Positives = 102/182 (56%), Gaps = 8/182 (4%)
Query: 356 SQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKT---VPLLSKV 412
+Q M +I+ C++ +E RG+ + GLYR+ G V+ L + VKT V L +
Sbjct: 389 AQLDKMGFTIIRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSA 448
Query: 413 D-DIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRD 471
D ++ I S LK +LR+L EPL+T+ L+ F+ A+ ++ + A++ V +LP+ N++
Sbjct: 449 DWEVKTITSALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKE 508
Query: 472 TLAFLMIHLQRVA-QSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVER 530
L L+ HL V+ S M VANL VFGPT++ P + V L D+K Q VVE
Sbjct: 509 MLDILVKHLTNVSNHSKQNLMTVANLGVVFGPTLMR---PQEETVAALMDLKFQNIVVEI 565
Query: 531 LL 532
L+
Sbjct: 566 LI 567
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 99.8 bits (247), Expect = 7e-21
Identities = 66/184 (35%), Positives = 99/184 (53%), Gaps = 10/184 (5%)
Query: 361 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS 420
+ P +V CV+ I +RGLTE GL+R+ G V++L++ F PL D+H + S
Sbjct: 171 LAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSF-DCGEKPLFDSTTDVHTVAS 229
Query: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEI--TDEDNSIAAMYQAVGELPQANRDTLAFLMI 478
LLK +LR L EP++ F F+ A++ DE + + V LPQAN + L ++
Sbjct: 230 LLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICK 289
Query: 479 HLQRV-AQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLE 537
L V A S KM V NLA VFGP I+ V DPVT+++ +V+ L+++ +
Sbjct: 290 FLDEVQAYSNVNKMSVQNLATVFGPNILRPQV--EDPVTIMEG----TSLVQHLMTVLIR 343
Query: 538 YWSQ 541
SQ
Sbjct: 344 KHSQ 347
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 98.6 bits (244), Expect = 2e-20
Identities = 77/272 (28%), Positives = 121/272 (44%), Gaps = 13/272 (4%)
Query: 264 RQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESCVPCGKRIKFGKLSLKCRDCRVVS 323
R+ + ETD V + NG H F + P C C I + C+ C+
Sbjct: 1983 RKKRRKKETDLV--EEHNG----HIFKATQYSIPTYCEYCSSLIWIMDRASVCKLCKYAC 2036
Query: 324 HPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGL 383
H +C + C G+ ++ +P +V +N IE GL G+
Sbjct: 2037 HKKCCLKTTAKCSKKYDPELSSRQFGVELSRLTSEDRTVPLVVEKLINYIEMHGLYTEGI 2096
Query: 384 YRISGCDRTVKELKEKFLRVKTVPLLSKVDD--IHAICSLLKDFLRNLKEPLLTFRLNRA 441
YR SG +KEL++ + T +DD IH I S+ K +LR+L PL+TF L
Sbjct: 2097 YRKSGSTNKIKELRQG---LDTDAESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEE 2153
Query: 442 FMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVA-QSPHTKMDVANLAKVF 500
F+ A + + +I +Y + +L + + +TL L+ HL R+A Q +M LA VF
Sbjct: 2154 FLRAMGLQERKETIRGVYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVF 2213
Query: 501 GPTIVAHAVPNPDPVTMLQDIKRQPKVVERLL 532
P I+ DP+ +QDI + VE ++
Sbjct: 2214 APCIL-RCPDTTDPLQSVQDISKTTTCVELIV 2244
>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
Length = 1227
Score = 97.8 bits (242), Expect = 3e-20
Identities = 58/146 (39%), Positives = 82/146 (56%), Gaps = 2/146 (1%)
Query: 362 IPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKF-LRVKTVPLLSKVDDIHAICS 420
+P IV CV EIE+RG+ E G+YR+SG ++ LK F + K V ++ D++AI
Sbjct: 1023 VPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAG 1082
Query: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL 480
LK + R L EPL T F E ++D + M + LP+AN T FL+ HL
Sbjct: 1083 TLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHL 1142
Query: 481 QRVAQSPH-TKMDVANLAKVFGPTIV 505
+RVA+ KM + NLA VFGPT++
Sbjct: 1143 KRVAEKEAVNKMSLHNLATVFGPTLL 1168
>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
Length = 1271
Score = 97.8 bits (242), Expect = 3e-20
Identities = 58/146 (39%), Positives = 82/146 (56%), Gaps = 2/146 (1%)
Query: 362 IPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKF-LRVKTVPLLSKVDDIHAICS 420
+P IV CV EIE+RG+ E G+YR+SG ++ LK F + K V ++ D++AI
Sbjct: 1067 VPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAG 1126
Query: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL 480
LK + R L EPL T F E ++D + M + LP+AN T FL+ HL
Sbjct: 1127 TLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHL 1186
Query: 481 QRVAQSPH-TKMDVANLAKVFGPTIV 505
+RVA+ KM + NLA VFGPT++
Sbjct: 1187 KRVAEKEAVNKMSLHNLATVFGPTLL 1212
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 97.1 bits (240), Expect = 5e-20
Identities = 68/218 (31%), Positives = 112/218 (51%), Gaps = 10/218 (4%)
Query: 356 SQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLR-VKTVPLLS-KVD 413
+ T+ IP IV C +E+RGL TG+YR+ G + + ++E+ + + + + K
Sbjct: 1155 AHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWR 1214
Query: 414 DIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTL 473
D++ I SLLK F R L EPL T F+EA D + + + + + +LP+ + +TL
Sbjct: 1215 DLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETL 1274
Query: 474 AFLMIHLQRVAQ-SPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLL 532
FL HL+ VA+ S KM+ NLA VFGPT+V + N M+ + Q K+VE L+
Sbjct: 1275 KFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDN--MTHMVTHMPDQYKIVETLI 1332
Query: 533 SLPLEYWSQFMMVEQENIDPLHVIENSNAFSTPQTPDI 570
+ E+ +PL ++ + + P+I
Sbjct: 1333 Q-----HHDWFFTEEGAEEPLTTVQEESTVDSQPVPNI 1365
>gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo
sapiens]
Length = 874
Score = 94.7 bits (234), Expect = 2e-19
Identities = 60/173 (34%), Positives = 99/173 (57%), Gaps = 7/173 (4%)
Query: 364 SIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLS---KVDDIHAICS 420
+ V C+ +E RG+T GLYRI G + V++L K+ P + ++ D I S
Sbjct: 396 NFVRKCIQAVETRGITILGLYRIGGVNSKVQKLMNTTFSPKSPPDIDIDIELWDNKTITS 455
Query: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL 480
LK++LR L EPL+T++L++ F+ A + D++ + A++ V +LP+ NR+ L L+ HL
Sbjct: 456 GLKNYLRCLAEPLMTYKLHKDFIIAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHL 515
Query: 481 QRVA-QSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLL 532
+V+ S M V+NL +FGPT++ + V + +IK Q VVE L+
Sbjct: 516 VKVSLHSQQNLMTVSNLGVIFGPTLMR---AQEETVAAMMNIKFQNIVVEILI 565
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 94.4 bits (233), Expect = 3e-19
Identities = 66/175 (37%), Positives = 93/175 (53%), Gaps = 7/175 (4%)
Query: 362 IPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLS--KVDDIHAIC 419
+P IV C +E RGL TG+YR+ G + V L+E+ R L + D++ I
Sbjct: 825 VPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLNVIS 884
Query: 420 SLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIH 479
SLLK F R L EPL T F+EA I D + + + + +LP +TL FL+ H
Sbjct: 885 SLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHYYETLKFLVGH 944
Query: 480 LQRVA-QSPHTKMDVANLAKVFGPTIVAHAVPN-PDPVTMLQDIKRQPKVVERLL 532
L+ +A S KM+ NLA VFGPT+V + N D VT + D + K+VE L+
Sbjct: 945 LKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPD---RYKIVETLI 996
>gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens]
Length = 1136
Score = 93.6 bits (231), Expect = 5e-19
Identities = 72/263 (27%), Positives = 120/263 (45%), Gaps = 33/263 (12%)
Query: 297 PESCVPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVS 356
P C C + F +C +C + H +C + + C + +++ +
Sbjct: 711 PAKCRECNSYVYFQ--GAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAAR 768
Query: 357 QTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIH 416
+P IV CV EIE+R L G+YR++G V++L + F K + LS+ H
Sbjct: 769 SAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASP-H 827
Query: 417 AICSLLKDFLRNLKEPLLTFRLNRAFMEAAEIT-----------------DEDNSIAA-- 457
I ++LK +LR L EPL++FRL + A+ + E ++A
Sbjct: 828 DISNVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVAL 887
Query: 458 ---MYQAVGELPQANRDTLAFLMIHLQRVAQ-SPHTKMDVANLAKVFGPTIVAHAVPNPD 513
+ + + +LP NR +L +L+ HL+R+ + KM NL VFGPT++ P P
Sbjct: 888 AGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLR---PRPT 944
Query: 514 PVTM----LQDIKRQPKVVERLL 532
T+ L D Q +V+E L+
Sbjct: 945 EATVSLSSLVDYPHQARVIETLI 967
>gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens]
Length = 1261
Score = 93.6 bits (231), Expect = 5e-19
Identities = 138/634 (21%), Positives = 258/634 (40%), Gaps = 98/634 (15%)
Query: 9 RNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHE-LGKYKDLLMKAETERSA 67
R L E+ +++VE E NE+ + + + E+ R + T E L + + L+ + + A
Sbjct: 372 RRLEEEALQKVE---EANELYKVCVT-NVEERRNDLENTKREILAQLRTLVFQCDLTLKA 427
Query: 68 LDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEEQK---SA 124
+ V L H ++ + ++ D KL Q E + S +EE+K +
Sbjct: 428 VTVNLFHMQHLQAASLADSLQSLCDSAKLYDPGQEYSEFVKATNS-----TEEEKVDGNV 482
Query: 125 LAFLNRGQPSSSNAGNKRLSTI---DESGSILSDISFDKTDESLDWDSSLVKTFKLKKRE 181
LN QPS N + D S I D + D + S ++++
Sbjct: 483 NKHLNSSQPSGFGPANSLEDVVRLPDSSNKIEEDRCSNSADIT---GPSFIRSWTFGMFS 539
Query: 182 KRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVPY 241
ST G ++RS+ S ESI P D
Sbjct: 540 DSEST---------GGSSESRSLDS------ESIS-------PGD--------------- 562
Query: 242 WTRSRRKTGTLQPWNSDSTLNSRQLEPRTET--DSVGTPQS---NGGMRLHDFVSKTVIK 296
+ R +T + +S L+ R+ +ET +S+GT + + H F + +
Sbjct: 563 FHRKLPRTPSSGTMSSADDLDEREPPSPSETGPNSLGTFKKTLMSKAALTHKF--RKLRS 620
Query: 297 PESCVPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVS 356
P C C + F ++C +C +V H +C + + C + + +
Sbjct: 621 PTKCRDCEGIVVFQ--GVECEECLLVCHRKCLENLVIICGHQKLPGKIHLFGAEFTQVAK 678
Query: 357 QTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIH 416
+ IP I+ C +EIE R L G+YR+ G ++L + + +S+ H
Sbjct: 679 KEPDGIPFILKICASEIENRALCLQGIYRVCGNKIKTEKLCQALENGMHLVDISEFSS-H 737
Query: 417 AICSLLKDFLRNLKEPLLTFRLNRAFMEAAE----ITDEDNS------------------ 454
IC +LK +LR L EP + FRL + F++ A+ + +E +
Sbjct: 738 DICDVLKLYLRQLPEPFILFRLYKEFIDLAKEIQHVNEEQETKKNSLEDKKWPNMCIEIN 797
Query: 455 --IAAMYQAVGELPQANRDTLAFLMIHLQRVA-QSPHTKMDVANLAKVFGPTIVAHAVPN 511
+ + +LP +N ++L FL++HL+RV + KM+ NL +FGP+++ P
Sbjct: 798 RILLKSKDLLRQLPASNFNSLHFLIVHLKRVVDHAEENKMNSKNLGVIFGPSLI-RPRPT 856
Query: 512 PDPVTM--LQDIKRQPKVVERLLSLPLEYWSQFMMVEQENIDPLHVIENS---NAFSTPQ 566
P+T+ L + Q ++VE L++ + + + Q+ + + V++ +P+
Sbjct: 857 TAPITISSLAEYSNQARLVEFLITYSQKIFDGSLQ-PQDVMCSIGVVDQGCFPKPLLSPE 915
Query: 567 TPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS 600
DI+ S+ + + + + S S + +R S
Sbjct: 916 ERDIERSMKSLFFSSKEDIHTSESESKIFERATS 949
>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
sapiens]
Length = 653
Score = 92.8 bits (229), Expect = 8e-19
Identities = 82/282 (29%), Positives = 130/282 (46%), Gaps = 25/282 (8%)
Query: 361 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS 420
+ P +V CV+ I QRGL E GL+R+ G VKEL++ F P D+H + S
Sbjct: 56 LAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAF-DCGEKPSFDSNTDVHTVAS 114
Query: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEI--TDEDNSIAAMYQAVGELPQANRDTLAFLMI 478
LLK +LR L EP++ + F+ A++ +E+ + + + V LP N + L ++
Sbjct: 115 LLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICR 174
Query: 479 HLQRV-AQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLE 537
L V + S KM V NLA VFGP I+ V DP+T+++ VV++L+S+ +
Sbjct: 175 FLDEVQSYSGVNKMSVQNLATVFGPNILRPKV--EDPLTIMEG----TVVVQQLMSVMIS 228
Query: 538 YWSQFMMVEQE-NIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLS- 595
+ E P + N+N K + +G + E+ K S S
Sbjct: 229 KHDCLFPKDAELQSKPQDGVSNNNEIQ-------KKATMGQLQNKENNNTKDSPSRQCSW 281
Query: 596 ----QRVRSTLTKNTPR--FGSKSKSATNLGRQGNFFASPML 631
RS++ +P GSK+ S N + + SP L
Sbjct: 282 DKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPL 323
>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
sapiens]
Length = 655
Score = 92.8 bits (229), Expect = 8e-19
Identities = 82/282 (29%), Positives = 130/282 (46%), Gaps = 25/282 (8%)
Query: 361 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS 420
+ P +V CV+ I QRGL E GL+R+ G VKEL++ F P D+H + S
Sbjct: 58 LAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAF-DCGEKPSFDSNTDVHTVAS 116
Query: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEI--TDEDNSIAAMYQAVGELPQANRDTLAFLMI 478
LLK +LR L EP++ + F+ A++ +E+ + + + V LP N + L ++
Sbjct: 117 LLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICR 176
Query: 479 HLQRV-AQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLE 537
L V + S KM V NLA VFGP I+ V DP+T+++ VV++L+S+ +
Sbjct: 177 FLDEVQSYSGVNKMSVQNLATVFGPNILRPKV--EDPLTIMEG----TVVVQQLMSVMIS 230
Query: 538 YWSQFMMVEQE-NIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLS- 595
+ E P + N+N K + +G + E+ K S S
Sbjct: 231 KHDCLFPKDAELQSKPQDGVSNNNEIQ-------KKATMGQLQNKENNNTKDSPSRQCSW 283
Query: 596 ----QRVRSTLTKNTPR--FGSKSKSATNLGRQGNFFASPML 631
RS++ +P GSK+ S N + + SP L
Sbjct: 284 DKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPL 325
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 92.8 bits (229), Expect = 8e-19
Identities = 82/282 (29%), Positives = 130/282 (46%), Gaps = 25/282 (8%)
Query: 361 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS 420
+ P +V CV+ I QRGL E GL+R+ G VKEL++ F P D+H + S
Sbjct: 151 LAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAF-DCGEKPSFDSNTDVHTVAS 209
Query: 421 LLKDFLRNLKEPLLTFRLNRAFMEAAEI--TDEDNSIAAMYQAVGELPQANRDTLAFLMI 478
LLK +LR L EP++ + F+ A++ +E+ + + + V LP N + L ++
Sbjct: 210 LLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICR 269
Query: 479 HLQRV-AQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLE 537
L V + S KM V NLA VFGP I+ V DP+T+++ VV++L+S+ +
Sbjct: 270 FLDEVQSYSGVNKMSVQNLATVFGPNILRPKV--EDPLTIMEG----TVVVQQLMSVMIS 323
Query: 538 YWSQFMMVEQE-NIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLS- 595
+ E P + N+N K + +G + E+ K S S
Sbjct: 324 KHDCLFPKDAELQSKPQDGVSNNNEIQ-------KKATMGQLQNKENNNTKDSPSRQCSW 376
Query: 596 ----QRVRSTLTKNTPR--FGSKSKSATNLGRQGNFFASPML 631
RS++ +P GSK+ S N + + SP L
Sbjct: 377 DKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPL 418
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 92.4 bits (228), Expect = 1e-18
Identities = 63/184 (34%), Positives = 92/184 (50%), Gaps = 5/184 (2%)
Query: 351 LADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLS 410
LA + +P V C+ +E RGL GLYRISG T+++L+ K + + L
Sbjct: 331 LAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDD 390
Query: 411 -KVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQAN 469
+ +D+H I LK F R L EPL F R F+ A ++ D+ + V LP N
Sbjct: 391 GRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLVRSLPAPN 450
Query: 470 RDTLAFLMIHLQRVAQ-SPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVV 528
DTL L HL RV + +M V ++A VFGPT++ P + +M + Q +VV
Sbjct: 451 HDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLR---PEVEETSMPMTMVFQNQVV 507
Query: 529 ERLL 532
E +L
Sbjct: 508 ELIL 511
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
sapiens]
Length = 548
Score = 92.4 bits (228), Expect = 1e-18
Identities = 63/184 (34%), Positives = 92/184 (50%), Gaps = 5/184 (2%)
Query: 351 LADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLS 410
LA + +P V C+ +E RGL GLYRISG T+++L+ K + + L
Sbjct: 358 LAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDD 417
Query: 411 -KVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQAN 469
+ +D+H I LK F R L EPL F R F+ A ++ D+ + V LP N
Sbjct: 418 GRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLVRSLPAPN 477
Query: 470 RDTLAFLMIHLQRVAQ-SPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVV 528
DTL L HL RV + +M V ++A VFGPT++ P + +M + Q +VV
Sbjct: 478 HDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLR---PEVEETSMPMTMVFQNQVV 534
Query: 529 ERLL 532
E +L
Sbjct: 535 ELIL 538
>gi|4505507 oligophrenin 1 [Homo sapiens]
Length = 802
Score = 92.0 bits (227), Expect = 1e-18
Identities = 60/168 (35%), Positives = 92/168 (54%), Gaps = 7/168 (4%)
Query: 369 CVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKT---VPLLSKVDDIHAICSLLKDF 425
C+N IE +G+ GLYR G + V++L F K V + DI I S LK +
Sbjct: 393 CINIIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSSLKFY 452
Query: 426 LRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVAQ 485
LRNL EP++T+RL++ + AA+ + D + A++ V +LP+ NR+ L L+ HL V +
Sbjct: 453 LRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCE 512
Query: 486 -SPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLL 532
S M +N+ +FGPT++ D V + +IK Q VVE L+
Sbjct: 513 HSKENLMTPSNMGVIFGPTLMR---AQEDTVAAMMNIKFQNIVVEILI 557
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,443,819
Number of Sequences: 37866
Number of extensions: 1087896
Number of successful extensions: 5071
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 137
Number of HSP's successfully gapped in prelim test: 170
Number of HSP's that attempted gapping in prelim test: 4503
Number of HSP's gapped (non-prelim): 577
length of query: 632
length of database: 18,247,518
effective HSP length: 108
effective length of query: 524
effective length of database: 14,157,990
effective search space: 7418786760
effective search space used: 7418786760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.