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Search of human proteins with 18426915
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18426915 drebrin 1 isoform a [Homo sapiens]
(649 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18426915 drebrin 1 isoform a [Homo sapiens] 1307 0.0
gi|18426913 drebrin 1 isoform b [Homo sapiens] 1251 0.0
gi|171906575 drebrin-like isoform c [Homo sapiens] 219 5e-57
gi|62198235 drebrin-like isoform b [Homo sapiens] 215 1e-55
gi|21361670 drebrin-like isoform a [Homo sapiens] 214 3e-55
gi|56549694 enabled homolog isoform a [Homo sapiens] 93 7e-19
gi|39930375 enabled homolog isoform b [Homo sapiens] 93 7e-19
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 71 3e-12
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 70 8e-12
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 67 5e-11
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 67 5e-11
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 67 5e-11
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 67 7e-11
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 67 7e-11
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 67 7e-11
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 67 7e-11
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 66 9e-11
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 65 1e-10
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 65 1e-10
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 65 2e-10
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 65 2e-10
gi|55741677 SET domain containing 1A [Homo sapiens] 65 2e-10
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 65 3e-10
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 64 3e-10
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 64 4e-10
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 64 4e-10
gi|148746195 trichohyalin [Homo sapiens] 64 4e-10
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 64 6e-10
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 64 6e-10
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 64 6e-10
>gi|18426915 drebrin 1 isoform a [Homo sapiens]
Length = 649
Score = 1307 bits (3383), Expect = 0.0
Identities = 649/649 (100%), Positives = 649/649 (100%)
Query: 1 MAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFEN 60
MAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFEN
Sbjct: 1 MAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFEN 60
Query: 61 QKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASS 120
QKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASS
Sbjct: 61 QKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASS 120
Query: 121 VEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQF 180
VEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQF
Sbjct: 121 VEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQF 180
Query: 181 WEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQ 240
WEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQ
Sbjct: 181 WEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQ 240
Query: 241 TLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERV 300
TLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERV
Sbjct: 241 TLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERV 300
Query: 301 ASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVT 360
ASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVT
Sbjct: 301 ASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVT 360
Query: 361 SSQPPPLPPPPPPAQETQEPSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAED 420
SSQPPPLPPPPPPAQETQEPSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAED
Sbjct: 361 SSQPPPLPPPPPPAQETQEPSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAED 420
Query: 421 LMFMESAEQAVLAAPVEPATADATEIHDAADTIETDTATADTTVANNVPPAATSLIDLWP 480
LMFMESAEQAVLAAPVEPATADATEIHDAADTIETDTATADTTVANNVPPAATSLIDLWP
Sbjct: 421 LMFMESAEQAVLAAPVEPATADATEIHDAADTIETDTATADTTVANNVPPAATSLIDLWP 480
Query: 481 GNGEGASTLQGEPRAPTPPSGTEVTLAEVPLLDEVAPEPLLPAGEGCATLLNFDELPEPP 540
GNGEGASTLQGEPRAPTPPSGTEVTLAEVPLLDEVAPEPLLPAGEGCATLLNFDELPEPP
Sbjct: 481 GNGEGASTLQGEPRAPTPPSGTEVTLAEVPLLDEVAPEPLLPAGEGCATLLNFDELPEPP 540
Query: 541 ATFCDPEEVEGEPLAAPQTPTLPSALEELEQEQEPEPHLLTNGETTQKEGTQASEGYFSQ 600
ATFCDPEEVEGEPLAAPQTPTLPSALEELEQEQEPEPHLLTNGETTQKEGTQASEGYFSQ
Sbjct: 541 ATFCDPEEVEGEPLAAPQTPTLPSALEELEQEQEPEPHLLTNGETTQKEGTQASEGYFSQ 600
Query: 601 SQEEEFAQSEELCAKAPPPVFYNKPPEIDITCWDADPVPEEEEGFEGGD 649
SQEEEFAQSEELCAKAPPPVFYNKPPEIDITCWDADPVPEEEEGFEGGD
Sbjct: 601 SQEEEFAQSEELCAKAPPPVFYNKPPEIDITCWDADPVPEEEEGFEGGD 649
>gi|18426913 drebrin 1 isoform b [Homo sapiens]
Length = 651
Score = 1251 bits (3237), Expect = 0.0
Identities = 620/620 (100%), Positives = 620/620 (100%)
Query: 30 ALYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGED 89
ALYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGED
Sbjct: 32 ALYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGED 91
Query: 90 VPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLR 149
VPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLR
Sbjct: 92 VPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLR 151
Query: 150 LREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQE 209
LREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQE
Sbjct: 152 LREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQE 211
Query: 210 RMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHM 269
RMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHM
Sbjct: 212 RMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHM 271
Query: 270 KKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGSHLDSHRRMA 329
KKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGSHLDSHRRMA
Sbjct: 272 KKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGSHLDSHRRMA 331
Query: 330 PTPIPTRSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEPSPILDSEET 389
PTPIPTRSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEPSPILDSEET
Sbjct: 332 PTPIPTRSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEPSPILDSEET 391
Query: 390 RAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPATADATEIHDA 449
RAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPATADATEIHDA
Sbjct: 392 RAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPATADATEIHDA 451
Query: 450 ADTIETDTATADTTVANNVPPAATSLIDLWPGNGEGASTLQGEPRAPTPPSGTEVTLAEV 509
ADTIETDTATADTTVANNVPPAATSLIDLWPGNGEGASTLQGEPRAPTPPSGTEVTLAEV
Sbjct: 452 ADTIETDTATADTTVANNVPPAATSLIDLWPGNGEGASTLQGEPRAPTPPSGTEVTLAEV 511
Query: 510 PLLDEVAPEPLLPAGEGCATLLNFDELPEPPATFCDPEEVEGEPLAAPQTPTLPSALEEL 569
PLLDEVAPEPLLPAGEGCATLLNFDELPEPPATFCDPEEVEGEPLAAPQTPTLPSALEEL
Sbjct: 512 PLLDEVAPEPLLPAGEGCATLLNFDELPEPPATFCDPEEVEGEPLAAPQTPTLPSALEEL 571
Query: 570 EQEQEPEPHLLTNGETTQKEGTQASEGYFSQSQEEEFAQSEELCAKAPPPVFYNKPPEID 629
EQEQEPEPHLLTNGETTQKEGTQASEGYFSQSQEEEFAQSEELCAKAPPPVFYNKPPEID
Sbjct: 572 EQEQEPEPHLLTNGETTQKEGTQASEGYFSQSQEEEFAQSEELCAKAPPPVFYNKPPEID 631
Query: 630 ITCWDADPVPEEEEGFEGGD 649
ITCWDADPVPEEEEGFEGGD
Sbjct: 632 ITCWDADPVPEEEEGFEGGD 651
>gi|171906575 drebrin-like isoform c [Homo sapiens]
Length = 439
Score = 219 bits (559), Expect = 5e-57
Identities = 132/372 (35%), Positives = 204/372 (54%), Gaps = 35/372 (9%)
Query: 2 AGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFENQ 61
A +S +G L+ AY V+ E+S DWAL+TYE S+D+++A +GEGGL+E+ +
Sbjct: 3 ANLSRNGPALQ--EAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEEMVEELNSG 60
Query: 62 KVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSV 121
KVMY FC VKD + LPK+VLINW GE V D RK ACASHV+ +A F +G V +NA +
Sbjct: 61 KVMYAFCRVKDPNSGLPKFVLINWTGEGVNDVRKGACASHVSTMASFLKGAHVTINARAE 120
Query: 122 EDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFW 181
ED++ I ++++ S R ++ PVG+ YQKT+A E+KR+ ++ FW
Sbjct: 121 EDVEPECIMEKVAKASGANYSFHKESGRFQDVGPQAPVGSVYQKTNAVSEIKRVGKDSFW 180
Query: 182 EQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQT 241
+A+KEEE R+ EE+++A + + + EQER E+E +E RE+RY+E+ + R +
Sbjct: 181 AKAEKEEENRRLEEKRRAEEAQRQLEQERRERELREAARREQRYQEQGGEASPQSRTWE- 239
Query: 242 LEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVA 301
++Q + +R+E+ T ES V +PRE FKQ+ER
Sbjct: 240 ----------QQQEVVSRNRNEQGSTCASLQESAV------------HPREIFKQKERAM 277
Query: 302 SASAGSCDVP----SPFNHRPGSHLDSHRRMAPTPIPTRS----PSDSSTASTPVAEQIE 353
S ++ S P SPF + + ++H P +R P++ STP +
Sbjct: 278 STTSISSPQPGKLRSPFLQKQLTQPETHFGREPAAAISRPRADLPAEEPAPSTPPC--LV 335
Query: 354 RALDEVTSSQPP 365
+A +E +PP
Sbjct: 336 QAEEEAVYEEPP 347
>gi|62198235 drebrin-like isoform b [Homo sapiens]
Length = 430
Score = 215 bits (547), Expect = 1e-55
Identities = 130/372 (34%), Positives = 201/372 (54%), Gaps = 44/372 (11%)
Query: 2 AGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFENQ 61
A +S +G L+ AY V+ E+S DWAL+TYE S+D+++A +GEGGL+E+ +
Sbjct: 3 ANLSRNGPALQ--EAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEEMVEELNSG 60
Query: 62 KVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSV 121
KVMY FC VKD + LPK+VLINW GE V D RK ACASHV+ +A F +G V +NA +
Sbjct: 61 KVMYAFCRVKDPNSGLPKFVLINWTGEGVNDVRKGACASHVSTMASFLKGAHVTINARAE 120
Query: 122 EDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFW 181
ED++ I ++++ S R ++ PVG+ YQKT+A E+KR+ ++ FW
Sbjct: 121 EDVEPECIMEKVAKASGANYSFHKESGRFQDVGPQAPVGSVYQKTNAVSEIKRVGKDSFW 180
Query: 182 EQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQT 241
+A+KEEE R+ EE+++A + + + EQER E+E +E RE+RY+E+ + R +Q
Sbjct: 181 AKAEKEEENRRLEEKRRAEEAQRQLEQERRERELREAARREQRYQEQGGEASPQRTWEQ- 239
Query: 242 LEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVA 301
+Q + +R+E+E +PRE FKQ+ER
Sbjct: 240 -----------QQEVVSRNRNEQESA--------------------VHPREIFKQKERAM 268
Query: 302 SASAGSCDVP----SPFNHRPGSHLDSHRRMAPTPIPTRS----PSDSSTASTPVAEQIE 353
S ++ S P SPF + + ++H P +R P++ STP +
Sbjct: 269 STTSISSPQPGKLRSPFLQKQLTQPETHFGREPAAAISRPRADLPAEEPAPSTPPC--LV 326
Query: 354 RALDEVTSSQPP 365
+A +E +PP
Sbjct: 327 QAEEEAVYEEPP 338
>gi|21361670 drebrin-like isoform a [Homo sapiens]
Length = 431
Score = 214 bits (544), Expect = 3e-55
Identities = 129/372 (34%), Positives = 201/372 (54%), Gaps = 43/372 (11%)
Query: 2 AGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFENQ 61
A +S +G L+ AY V+ E+S DWAL+TYE S+D+++A +GEGGL+E+ +
Sbjct: 3 ANLSRNGPALQ--EAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEEMVEELNSG 60
Query: 62 KVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSV 121
KVMY FC VKD + LPK+VLINW GE V D RK ACASHV+ +A F +G V +NA +
Sbjct: 61 KVMYAFCRVKDPNSGLPKFVLINWTGEGVNDVRKGACASHVSTMASFLKGAHVTINARAE 120
Query: 122 EDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFW 181
ED++ I ++++ S R ++ PVG+ YQKT+A E+KR+ ++ FW
Sbjct: 121 EDVEPECIMEKVAKASGANYSFHKESGRFQDVGPQAPVGSVYQKTNAVSEIKRVGKDSFW 180
Query: 182 EQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQT 241
+A+KEEE R+ EE+++A + + + EQER E+E +E RE+RY+E+ + R +
Sbjct: 181 AKAEKEEENRRLEEKRRAEEAQRQLEQERRERELREAARREQRYQEQGGEASPQSRTWE- 239
Query: 242 LEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVA 301
++Q + +R+E+E +PRE FKQ+ER
Sbjct: 240 ----------QQQEVVSRNRNEQESA--------------------VHPREIFKQKERAM 269
Query: 302 SASAGSCDVP----SPFNHRPGSHLDSHRRMAPTPIPTRS----PSDSSTASTPVAEQIE 353
S ++ S P SPF + + ++H P +R P++ STP +
Sbjct: 270 STTSISSPQPGKLRSPFLQKQLTQPETHFGREPAAAISRPRADLPAEEPAPSTPPC--LV 327
Query: 354 RALDEVTSSQPP 365
+A +E +PP
Sbjct: 328 QAEEEAVYEEPP 339
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 93.2 bits (230), Expect = 7e-19
Identities = 98/374 (26%), Positives = 151/374 (40%), Gaps = 43/374 (11%)
Query: 141 SSPVLHRLRLREDENAEPVGTTYQKTDAAV----------EMKRINREQFWEQAKKEEEL 190
+S ++H L + N++ G T + ++ + E I R Q EQ +++E
Sbjct: 101 ASAMMHALEVL---NSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELE 157
Query: 191 RKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRR 250
R+ ER++ ER R E+ER+E+ER E+E E+ ERE+Q E + + + E E + R
Sbjct: 158 RERLERERM--ERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQER 215
Query: 251 LKEQSIFGDHRDE-EEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCD 309
L+ Q R E +E +++ E E +E Q + ++ER S++A
Sbjct: 216 LERQERLDRERQERQERERLERLERERQERE---RQEQLEREQLEWERERRISSAAAPAS 272
Query: 310 VPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERAL-----DEVTSSQP 364
V +P N G S + P +PS P+A L + P
Sbjct: 273 VETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPP 332
Query: 365 PPLPPPPPPAQETQEPSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFM 424
PP PPPPPP T P P P P + PP PP P PA
Sbjct: 333 PPGPPPPPPLPSTGPPPP-----------PPPPPLPNQVPPPPPPPP-APPLPASGFFLA 380
Query: 425 ESAEQAVLAAPVEPATADATEIHDAADTIETDTATADTTVANNVPPAATSLIDLWPGNGE 484
+E + A A A ++ + +T + + N +A+S D GNG
Sbjct: 381 SMSEDNRPLTGLAAAIAGA-KLRKVSRMEDTSFPSGGNAIGVN---SASSKTDTGRGNGP 436
Query: 485 ---GASTLQGEPRA 495
G S L E A
Sbjct: 437 LPLGGSGLMEEMSA 450
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 93.2 bits (230), Expect = 7e-19
Identities = 98/374 (26%), Positives = 151/374 (40%), Gaps = 43/374 (11%)
Query: 141 SSPVLHRLRLREDENAEPVGTTYQKTDAAV----------EMKRINREQFWEQAKKEEEL 190
+S ++H L + N++ G T + ++ + E I R Q EQ +++E
Sbjct: 101 ASAMMHALEVL---NSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELE 157
Query: 191 RKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRR 250
R+ ER++ ER R E+ER+E+ER E+E E+ ERE+Q E + + + E E + R
Sbjct: 158 RERLERERM--ERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQER 215
Query: 251 LKEQSIFGDHRDE-EEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCD 309
L+ Q R E +E +++ E E +E Q + ++ER S++A
Sbjct: 216 LERQERLDRERQERQERERLERLERERQERE---RQEQLEREQLEWERERRISSAAAPAS 272
Query: 310 VPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERAL-----DEVTSSQP 364
V +P N G S + P +PS P+A L + P
Sbjct: 273 VETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPP 332
Query: 365 PPLPPPPPPAQETQEPSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFM 424
PP PPPPPP T P P P P + PP PP P PA
Sbjct: 333 PPGPPPPPPLPSTGPPPP-----------PPPPPLPNQVPPPPPPPP-APPLPASGFFLA 380
Query: 425 ESAEQAVLAAPVEPATADATEIHDAADTIETDTATADTTVANNVPPAATSLIDLWPGNGE 484
+E + A A A ++ + +T + + N +A+S D GNG
Sbjct: 381 SMSEDNRPLTGLAAAIAGA-KLRKVSRMEDTSFPSGGNAIGVN---SASSKTDTGRGNGP 436
Query: 485 ---GASTLQGEPRA 495
G S L E A
Sbjct: 437 LPLGGSGLMEEMSA 450
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 71.2 bits (173), Expect = 3e-12
Identities = 103/484 (21%), Positives = 182/484 (37%), Gaps = 54/484 (11%)
Query: 124 IDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQ 183
I G I L GL ++ S H ++++ +E + V + ++T + ++ Q E+
Sbjct: 413 IGFGPIPFSLPEGLPKIPSVSTH-IKVKSEEKIKVVEKSEKET--VIVEEQTEETQVTEE 469
Query: 184 AKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQI----------- 232
+EEE +EE K + E E E+E + E E+E +
Sbjct: 470 VTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAE 529
Query: 233 ------EEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMK-----KSESEVEEAAA 281
EE + + E+AK KE++ E+ K KS + + A
Sbjct: 530 AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAK 589
Query: 282 IIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHR---PGSHLDSHRRMAPTPIPTRSP 338
A+ P + K + V + + SP P + +PT +SP
Sbjct: 590 EEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSP 649
Query: 339 SDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEPSPILDSEETRAAAPQAWA 398
+ + A+ E+A V + P P E + P + A +P+
Sbjct: 650 EKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAK 709
Query: 399 GPMEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPATADATEIHDAADTIETDTA 458
P++E +A++P + E+ E A+ V P A + E A T++ +
Sbjct: 710 SPVKE--EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE---KAKTLDVKSP 764
Query: 459 TADTTVANNVPPAATSLIDLWPGNGEGASTLQGEPRAPTPPSGTEVTLAEVPLLDEV-AP 517
A T A S D +P + S ++ E ++P A+ PL ++ AP
Sbjct: 765 EAKTPAKEE----ARSPADKFPEKAK--SPVKEEVKSPEK--------AKSPLKEDAKAP 810
Query: 518 EPLLPAGEGCATLLNFDELPEPPATFCDPEEVEGEPLAAPQTPTL----PSALEELEQEQ 573
E +P E + + +E P+ P++ E E AP TP S EE +++
Sbjct: 811 EKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE--KAPATPKTEEKKDSKKEEAPKKE 868
Query: 574 EPEP 577
P+P
Sbjct: 869 APKP 872
Score = 35.8 bits (81), Expect = 0.13
Identities = 33/133 (24%), Positives = 63/133 (47%), Gaps = 14/133 (10%)
Query: 152 EDENAEPVGTTYQKTDAAVEMKR-INREQFWEQAKKEEELRKEEERKKALDERLRFEQER 210
E E+ + V T ++ A VE+K ++ E AKKE + K +E K +++ E
Sbjct: 896 EAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKK-----EA 950
Query: 211 MEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLK--EQSIFGDHRDEEEETH 268
+++ +EE+ ++ E+ + + + +TL E +K + + E+S D +D
Sbjct: 951 APEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDS----- 1005
Query: 269 MKKSESEVEEAAA 281
K E E+ AA
Sbjct: 1006 -KPPEKATEDKAA 1017
Score = 33.9 bits (76), Expect = 0.48
Identities = 34/173 (19%), Positives = 81/173 (46%), Gaps = 23/173 (13%)
Query: 140 LSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELR-KEEERKK 198
+ SPV + +E + EP ++ A ++ E+A K+E + K EE+K+
Sbjct: 820 VKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKE 879
Query: 199 ALDERLRFEQERMEQERQEQEER------ERRYREREQQIEEHRRKQQT---------LE 243
E+ + + ++E +++E E++ E+ + + E+ + K++T +
Sbjct: 880 PAVEKPK--ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAK 937
Query: 244 AEEAKRRLKEQSIFGDHRDEEEETHMK-----KSESEVEEAAAIIAQRPDNPR 291
A+E + +++ + +D +EE K K+E++ +E +++ P P+
Sbjct: 938 AKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPK 990
Score = 32.3 bits (72), Expect = 1.4
Identities = 47/247 (19%), Positives = 95/247 (38%), Gaps = 35/247 (14%)
Query: 169 AVEMKRINREQFWEQAKK--EEELRKEEERKKALDERLRFEQERMEQE-------RQEQE 219
A E R ++F E+AK +EE++ E+ K L E + ++ + ++ ++E++
Sbjct: 770 AKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK 829
Query: 220 ERERRYREREQQIEEHR--------RKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKK 271
+E + +E ++ EE + K+ + + E K+ + + E+ K
Sbjct: 830 PQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESK 889
Query: 272 SESEVEEA---AAIIAQRPDNP-----REFFKQQERVASASAGSCDVPSPFNHRPGSHLD 323
E++ EEA + + P +E K +E+ A D + +P
Sbjct: 890 VEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPA---- 945
Query: 324 SHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEPSPI 383
+ AP T+ P E + D+ S + P P E E S
Sbjct: 946 EKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE------PSKPKAEKAEKSSS 999
Query: 384 LDSEETR 390
D ++++
Sbjct: 1000 TDQKDSK 1006
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 69.7 bits (169), Expect = 8e-12
Identities = 66/299 (22%), Positives = 128/299 (42%), Gaps = 52/299 (17%)
Query: 164 QKTDAAVEMKRINREQFWEQ--------AKKEEELRKEEERKKALDERLRFEQERMEQER 215
++++A + + +Q EQ A++++ + +++E+++ L+E+ R E+E Q+
Sbjct: 365 ERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQE 424
Query: 216 QEQEERERRYREREQQIEEHRRKQQTLE-AEEAKRRLKEQSIFGDHRDEEEETHMKKSES 274
+EQ RE+ + R +++E R++++ AEE KRR++ + + + EEE+ H++ +
Sbjct: 425 REQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQ 484
Query: 275 EV--EEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNH---------------- 316
++ E+A + R +P+ + S S P P H
Sbjct: 485 QLLQEQAMLLHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVEDRFRK 544
Query: 317 ----RPGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPP 372
P + R+ P+P+RS S S+ S V ++R P P
Sbjct: 545 TNHSSPEAQSKQTGRVLEPPVPSRSESFSNGNSESVHPALQR-------------PAEPQ 591
Query: 373 PAQETQEPSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFMESAEQAV 431
T SP+L +R +P +G +QA R S E + E E+ V
Sbjct: 592 VPVRTTSRSPVL----SRRDSPLQGSGQQ----NSQAGQRNSTSSIEPRLLWERVEKLV 642
Score = 48.1 bits (113), Expect = 2e-05
Identities = 34/124 (27%), Positives = 67/124 (54%), Gaps = 9/124 (7%)
Query: 182 EQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRY-REREQQIEEHRRKQQ 240
E + + LR ++E K+ E LR +Q EQ+ +EQEE +R+ ER+++IE+ + +++
Sbjct: 349 ESTLRRDFLRLQQENKER-SEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRR 407
Query: 241 TLEAEEAKRR--LKEQSIFGDHRDEE-----EETHMKKSESEVEEAAAIIAQRPDNPREF 293
LE ++ + R ++Q R++E EE ++ E E A +R + +E+
Sbjct: 408 RLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEY 467
Query: 294 FKQQ 297
++Q
Sbjct: 468 IRRQ 471
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 67.0 bits (162), Expect = 5e-11
Identities = 77/369 (20%), Positives = 146/369 (39%), Gaps = 63/369 (17%)
Query: 164 QKTDAAVEMKRINREQFWEQ--------AKKEEELRKEEERKKALDERLRFEQERMEQER 215
++++A + + +Q EQ A++++ + +++E+++ L+E+ R E+E Q+
Sbjct: 365 ERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQE 424
Query: 216 QEQEERERRYREREQQIEEHRRKQQTLE-AEEAKRRLKEQSIFGDHRDEEEETHMKKSES 274
+EQ RE+ + R +++E R++++ AEE KRR++ + + + EEE+ H++ +
Sbjct: 425 REQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQ 484
Query: 275 EVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIP 334
++ + A++ + E +Q ER+ H HRR P P
Sbjct: 485 QLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQH-------DHRR--PHPQH 535
Query: 335 TRSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEPSPILDSEETRAAAP 394
++ P PPP P+ EP + +
Sbjct: 536 SQQP-------------------------PPPQQERSKPSFHAPEPKAHYEPADRAREVE 570
Query: 395 QAWAGPMEEPPQAQAPPRG----PGSPAEDLMFMESAEQAVLAAPVEPATADATEIHDAA 450
+ P+AQ+ G P P+ F ++V A PA H A
Sbjct: 571 DRFRKTNHSSPEAQSKQTGRVLEPPVPSRSESFSNGNSESVHPALQRPAEPQVQWSHLA- 629
Query: 451 DTIETDTATADTTVANNVPPAATSLIDLWPGNGEGASTLQGEPRAPTPPSGTEVTLAEVP 510
++ NNV P + S P L+ + P PPS +EV L++
Sbjct: 630 ------------SLKNNVSPVSRSHSFSDPSPKFAHHHLRSQD--PCPPSRSEV-LSQSS 674
Query: 511 LLDEVAPEP 519
AP+P
Sbjct: 675 DSKSEAPDP 683
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 67.0 bits (162), Expect = 5e-11
Identities = 57/151 (37%), Positives = 82/151 (54%), Gaps = 24/151 (15%)
Query: 177 REQFWEQAKKEEE---LRKEEERKKALDERL--RFEQERMEQERQEQE--ERERRYRERE 229
R Q Q KKEEE LRK E K+ ++R R EQER EQER+EQE E+ERR +ER+
Sbjct: 659 RHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQ 718
Query: 230 QQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDN 289
+E RR+Q+ L+AE R L+E R++ ++ + E+EE Q+
Sbjct: 719 LAEQERRREQERLQAE---RELQE-------REKALRLQKEQLQRELEEKKKKEEQQRLA 768
Query: 290 PREFFKQQERVASASAG-------SCDVPSP 313
R+ ++QE+ A +AG + DV SP
Sbjct: 769 ERQLQEEQEKKAKEAAGASKALNVTVDVQSP 799
Score = 57.4 bits (137), Expect = 4e-08
Identities = 38/109 (34%), Positives = 65/109 (59%), Gaps = 8/109 (7%)
Query: 169 AVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERM--EQERQEQEER---ER 223
A E KR+ ++ EQ ++E+E R++E R++ E+ R EQER EQER+ ++ER ER
Sbjct: 678 AAEAKRLAEQR--EQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAER 735
Query: 224 RYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKS 272
+ERE+ + + + Q E EE K++ ++Q + EE+E K++
Sbjct: 736 ELQEREKALRLQKEQLQR-ELEEKKKKEEQQRLAERQLQEEQEKKAKEA 783
Score = 49.3 bits (116), Expect = 1e-05
Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 45/202 (22%)
Query: 145 LHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAK------KEEELRKEEERKK 198
L ++L+ +E V ++ + E K+ EQ + Q KEE L +E+ +KK
Sbjct: 567 LEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKK 626
Query: 199 ALDERLRFEQERMEQERQ-------EQEERERRYRE------------------------ 227
A +++ + R +QE + +QEE ERR++E
Sbjct: 627 AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAE 686
Query: 228 -REQQI-EEHRRKQQTLEAE--EAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAII 283
REQ+ E+ RR+Q+ E E E +RR +E+ + R E+E + E + E A +
Sbjct: 687 QREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRL 746
Query: 284 ----AQRPDNPREFFKQQERVA 301
QR ++ ++Q+R+A
Sbjct: 747 QKEQLQRELEEKKKKEEQQRLA 768
Score = 48.5 bits (114), Expect = 2e-05
Identities = 31/106 (29%), Positives = 58/106 (54%), Gaps = 5/106 (4%)
Query: 178 EQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEE--H 235
EQ Q +E++ R+ EE K +ERLR + E+ Q +EE++++ ++ QI+E
Sbjct: 552 EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTE 611
Query: 236 RRKQQTLEAEEAKRRL---KEQSIFGDHRDEEEETHMKKSESEVEE 278
+ K++ L E+AK++ K + + + EEE ++ + E EE
Sbjct: 612 KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEE 657
Score = 43.5 bits (101), Expect = 6e-04
Identities = 33/124 (26%), Positives = 66/124 (53%), Gaps = 13/124 (10%)
Query: 182 EQAKKEEELRKEEE----RKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRR 237
++ ++ E LR++EE R++ ++E R E ++ +R+E+ + + RER +Q++E ++
Sbjct: 537 KERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKK 596
Query: 238 K---QQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFF 294
K Q+ + +E + KE+ R EE+ K + ++EE A Q + R +
Sbjct: 597 KQIEQKFAQIDEKTEKAKEE------RLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRW 650
Query: 295 KQQE 298
QQE
Sbjct: 651 LQQE 654
Score = 38.1 bits (87), Expect = 0.026
Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 193 EEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLK 252
E+ER++ E LR ++E + RQ+ EE +RR R E +++ R ++ L+A E ++K
Sbjct: 536 EKERQRL--ENLRRKEEAEQLRRQKVEEDKRR-RLEEVKLKREERLRKVLQARERVEQMK 592
Query: 253 EQ---SIFGDHRDEEEETHMKKSESEVEEAA 280
E+ I +E+T K E EE A
Sbjct: 593 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKA 623
Score = 37.4 bits (85), Expect = 0.044
Identities = 49/214 (22%), Positives = 87/214 (40%), Gaps = 41/214 (19%)
Query: 188 EELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEA 247
EE+++E ER E E M + ++ R++R R +++ R +
Sbjct: 35 EEIQEEAERM--FTREFSKEPELMPKTPSQKNRRKKR---RISYVQDENR-------DPI 82
Query: 248 KRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGS 307
+RRL + R + + +S+ VE+ A ++ + N + A+A+A +
Sbjct: 83 RRRLSRRK----SRSSQLSSRRLRSKDSVEKLATVVGE---NGSVLRRVTRAAAAAAAAT 135
Query: 308 CDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDSSTAS--TPVAE-------QIERALDE 358
+ +P + P S PT + T+ P D+ T PV E E+ + +
Sbjct: 136 MALAAPSSPTPES---------PTML-TKKPEDNHTQCQLVPVVEIGISERQNAEQHVTQ 185
Query: 359 VTSSQPPPLPPPPPPAQETQEPS---PILDSEET 389
+ S++P P P PA T S P D E T
Sbjct: 186 LMSTEPLPRTLSPTPASATAPTSQGIPTSDEEST 219
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 67.0 bits (162), Expect = 5e-11
Identities = 57/151 (37%), Positives = 82/151 (54%), Gaps = 24/151 (15%)
Query: 177 REQFWEQAKKEEE---LRKEEERKKALDERL--RFEQERMEQERQEQE--ERERRYRERE 229
R Q Q KKEEE LRK E K+ ++R R EQER EQER+EQE E+ERR +ER+
Sbjct: 655 RHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQ 714
Query: 230 QQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDN 289
+E RR+Q+ L+AE R L+E R++ ++ + E+EE Q+
Sbjct: 715 LAEQERRREQERLQAE---RELQE-------REKALRLQKEQLQRELEEKKKKEEQQRLA 764
Query: 290 PREFFKQQERVASASAG-------SCDVPSP 313
R+ ++QE+ A +AG + DV SP
Sbjct: 765 ERQLQEEQEKKAKEAAGASKALNVTVDVQSP 795
Score = 57.4 bits (137), Expect = 4e-08
Identities = 38/109 (34%), Positives = 65/109 (59%), Gaps = 8/109 (7%)
Query: 169 AVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERM--EQERQEQEER---ER 223
A E KR+ ++ EQ ++E+E R++E R++ E+ R EQER EQER+ ++ER ER
Sbjct: 674 AAEAKRLAEQR--EQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAER 731
Query: 224 RYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKS 272
+ERE+ + + + Q E EE K++ ++Q + EE+E K++
Sbjct: 732 ELQEREKALRLQKEQLQR-ELEEKKKKEEQQRLAERQLQEEQEKKAKEA 779
Score = 49.3 bits (116), Expect = 1e-05
Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 45/202 (22%)
Query: 145 LHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAK------KEEELRKEEERKK 198
L ++L+ +E V ++ + E K+ EQ + Q KEE L +E+ +KK
Sbjct: 563 LEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKK 622
Query: 199 ALDERLRFEQERMEQERQ-------EQEERERRYRE------------------------ 227
A +++ + R +QE + +QEE ERR++E
Sbjct: 623 AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAE 682
Query: 228 -REQQI-EEHRRKQQTLEAE--EAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAII 283
REQ+ E+ RR+Q+ E E E +RR +E+ + R E+E + E + E A +
Sbjct: 683 QREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRL 742
Query: 284 ----AQRPDNPREFFKQQERVA 301
QR ++ ++Q+R+A
Sbjct: 743 QKEQLQRELEEKKKKEEQQRLA 764
Score = 48.5 bits (114), Expect = 2e-05
Identities = 31/106 (29%), Positives = 58/106 (54%), Gaps = 5/106 (4%)
Query: 178 EQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEE--H 235
EQ Q +E++ R+ EE K +ERLR + E+ Q +EE++++ ++ QI+E
Sbjct: 548 EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTE 607
Query: 236 RRKQQTLEAEEAKRRL---KEQSIFGDHRDEEEETHMKKSESEVEE 278
+ K++ L E+AK++ K + + + EEE ++ + E EE
Sbjct: 608 KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEE 653
Score = 43.1 bits (100), Expect = 8e-04
Identities = 35/138 (25%), Positives = 70/138 (50%), Gaps = 12/138 (8%)
Query: 164 QKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERER 223
+ T ++ K R++ E +++EE + +K D+R R E+ ++ +R+E+ +
Sbjct: 522 RNTPLRMDPKEKERQRL-ENLRRKEEAEQLRRQKVEEDKRRRLEEVKL--KREERLRKVL 578
Query: 224 RYREREQQIEEHRRK---QQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAA 280
+ RER +Q++E ++K Q+ + +E + KE+ R EE+ K + ++EE
Sbjct: 579 QARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEE------RLAEEKAKKKAAAKKMEEVE 632
Query: 281 AIIAQRPDNPREFFKQQE 298
A Q + R + QQE
Sbjct: 633 ARRKQEEEARRLRWLQQE 650
Score = 37.4 bits (85), Expect = 0.044
Identities = 49/214 (22%), Positives = 87/214 (40%), Gaps = 41/214 (19%)
Query: 188 EELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEA 247
EE+++E ER E E M + ++ R++R R +++ R +
Sbjct: 35 EEIQEEAERM--FTREFSKEPELMPKTPSQKNRRKKR---RISYVQDENR-------DPI 82
Query: 248 KRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGS 307
+RRL + R + + +S+ VE+ A ++ + N + A+A+A +
Sbjct: 83 RRRLSRRK----SRSSQLSSRRLRSKDSVEKLATVVGE---NGSVLRRVTRAAAAAAAAT 135
Query: 308 CDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDSSTAS--TPVAE-------QIERALDE 358
+ +P + P S PT + T+ P D+ T PV E E+ + +
Sbjct: 136 MALAAPSSPTPES---------PTML-TKKPEDNHTQCQLVPVVEIGISERQNAEQHVTQ 185
Query: 359 VTSSQPPPLPPPPPPAQETQEPS---PILDSEET 389
+ S++P P P PA T S P D E T
Sbjct: 186 LMSTEPLPRTLSPTPASATAPTSQGIPTSDEEST 219
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 66.6 bits (161), Expect = 7e-11
Identities = 47/158 (29%), Positives = 78/158 (49%), Gaps = 21/158 (13%)
Query: 175 INREQFWEQAKKEEE----LRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQ 230
+ R+Q E+ ++EEE ++EE ++ ++ + ++R E+ERQ+QEE RR ER +
Sbjct: 763 LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRR 822
Query: 231 QIEEHRRKQQTL-------------EAEEAKRRLKEQSIFGDH---RDEEEETHMKKSES 274
+ EE RRKQ+ L E EEA+RRL+E + + R EE K+ E
Sbjct: 823 E-EEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 881
Query: 275 EVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPS 312
EV+ ++ QR + Q++ +PS
Sbjct: 882 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPS 919
Score = 64.3 bits (155), Expect = 3e-10
Identities = 49/160 (30%), Positives = 88/160 (55%), Gaps = 14/160 (8%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEE---RKKALDERLR 205
+L++ E A+ ++ +A + KR E+ K++EELR+++E R++ +ER R
Sbjct: 719 QLQQLEKAKAAKLEQERREAEMRAKREEEER-----KRQEELRRQQEEILRRQQEEERKR 773
Query: 206 FEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEE 265
E+E E R++QEE RR RE+E + R +++ + EEA RRL+E+ + R ++E
Sbjct: 774 REEE--ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 831
Query: 266 ETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASA 305
E ++K E EEAA + + R + + R+ +A
Sbjct: 832 EL-LRKQE---EEAAKWAREEEEAQRRLEENRLRMEEEAA 867
Score = 50.4 bits (119), Expect = 5e-06
Identities = 42/119 (35%), Positives = 67/119 (56%), Gaps = 25/119 (21%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEEL------------RKEEER 196
R RE+E + Q+ +A ++ RE+ E+ +K+EEL R+EEE
Sbjct: 800 RQREEEERQ------QQEEALRRLEERRREE--EERRKQEELLRKQEEEAAKWAREEEEA 851
Query: 197 KKALDE-RLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQ 254
++ L+E RLR E+E R E+EER+R+ E ++Q E R++QQ +EA RRL++Q
Sbjct: 852 QRRLEENRLRMEEEAARL-RHEEEERKRKELEVQRQKELMRQRQQ---QQEALRRLQQQ 906
Score = 35.8 bits (81), Expect = 0.13
Identities = 36/188 (19%), Positives = 83/188 (44%), Gaps = 40/188 (21%)
Query: 151 REDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEE----RKKALDERLRF 206
+++E A ++ +E R+ E+ + + EEE RK +E R+K L + +
Sbjct: 836 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 895
Query: 207 EQERMEQERQEQEER---------------------------------ERRYREREQQIE 233
+QE + + +Q+Q+++ ++ ERE+Q+
Sbjct: 896 QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLR 955
Query: 234 EHRRKQQ--TLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPR 291
E +R+QQ ++A + +++ ++Q + G + + + KS E+++ A Q+ +
Sbjct: 956 EEQRRQQRELMKALQQQQQQQQQKLSG-WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1014
Query: 292 EFFKQQER 299
+ +Q R
Sbjct: 1015 QQHQQPNR 1022
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 66.6 bits (161), Expect = 7e-11
Identities = 47/158 (29%), Positives = 78/158 (49%), Gaps = 21/158 (13%)
Query: 175 INREQFWEQAKKEEE----LRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQ 230
+ R+Q E+ ++EEE ++EE ++ ++ + ++R E+ERQ+QEE RR ER +
Sbjct: 790 LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRR 849
Query: 231 QIEEHRRKQQTL-------------EAEEAKRRLKEQSIFGDH---RDEEEETHMKKSES 274
+ EE RRKQ+ L E EEA+RRL+E + + R EE K+ E
Sbjct: 850 E-EEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 908
Query: 275 EVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPS 312
EV+ ++ QR + Q++ +PS
Sbjct: 909 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPS 946
Score = 64.3 bits (155), Expect = 3e-10
Identities = 49/160 (30%), Positives = 88/160 (55%), Gaps = 14/160 (8%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEE---RKKALDERLR 205
+L++ E A+ ++ +A + KR E+ K++EELR+++E R++ +ER R
Sbjct: 746 QLQQLEKAKAAKLEQERREAEMRAKREEEER-----KRQEELRRQQEEILRRQQEEERKR 800
Query: 206 FEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEE 265
E+E E R++QEE RR RE+E + R +++ + EEA RRL+E+ + R ++E
Sbjct: 801 REEE--ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 858
Query: 266 ETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASA 305
E ++K E EEAA + + R + + R+ +A
Sbjct: 859 EL-LRKQE---EEAAKWAREEEEAQRRLEENRLRMEEEAA 894
Score = 50.4 bits (119), Expect = 5e-06
Identities = 42/119 (35%), Positives = 67/119 (56%), Gaps = 25/119 (21%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEEL------------RKEEER 196
R RE+E + Q+ +A ++ RE+ E+ +K+EEL R+EEE
Sbjct: 827 RQREEEERQ------QQEEALRRLEERRREE--EERRKQEELLRKQEEEAAKWAREEEEA 878
Query: 197 KKALDE-RLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQ 254
++ L+E RLR E+E R E+EER+R+ E ++Q E R++QQ +EA RRL++Q
Sbjct: 879 QRRLEENRLRMEEEAARL-RHEEEERKRKELEVQRQKELMRQRQQ---QQEALRRLQQQ 933
Score = 35.8 bits (81), Expect = 0.13
Identities = 36/188 (19%), Positives = 83/188 (44%), Gaps = 40/188 (21%)
Query: 151 REDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEE----RKKALDERLRF 206
+++E A ++ +E R+ E+ + + EEE RK +E R+K L + +
Sbjct: 863 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 922
Query: 207 EQERMEQERQEQEER---------------------------------ERRYREREQQIE 233
+QE + + +Q+Q+++ ++ ERE+Q+
Sbjct: 923 QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLR 982
Query: 234 EHRRKQQ--TLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPR 291
E +R+QQ ++A + +++ ++Q + G + + + KS E+++ A Q+ +
Sbjct: 983 EEQRRQQRELMKALQQQQQQQQQKLSG-WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1041
Query: 292 EFFKQQER 299
+ +Q R
Sbjct: 1042 QQHQQPNR 1049
Score = 33.5 bits (75), Expect = 0.63
Identities = 43/227 (18%), Positives = 82/227 (36%), Gaps = 50/227 (22%)
Query: 154 ENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQ 213
E+AE T+ + A + +K++ +E E+ +E + R +E ++ D +E E
Sbjct: 313 EDAEEEMGTFDSSGAFLSLKKVQKEPIPEE--QEMDFRPVDEGEECSDSEGSHNEEAKEP 370
Query: 214 ERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSE 273
++ ++E E+ R E + + +++ + +DE + +K+E
Sbjct: 371 DKTNKKEGEKTDRVGVASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAE 430
Query: 274 SEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPI 333
E ++ A+ P + E VA DV P + P
Sbjct: 431 EETRMENSLPAKVPS------RGDEMVA-------DVQQPLSQIP--------------- 462
Query: 334 PTRSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEP 380
S TAS + PPP+P P P + + P
Sbjct: 463 -------SDTASPLLI-------------LPPPVPNPSPTLRPVETP 489
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 66.6 bits (161), Expect = 7e-11
Identities = 47/158 (29%), Positives = 78/158 (49%), Gaps = 21/158 (13%)
Query: 175 INREQFWEQAKKEEE----LRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQ 230
+ R+Q E+ ++EEE ++EE ++ ++ + ++R E+ERQ+QEE RR ER +
Sbjct: 769 LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRR 828
Query: 231 QIEEHRRKQQTL-------------EAEEAKRRLKEQSIFGDH---RDEEEETHMKKSES 274
+ EE RRKQ+ L E EEA+RRL+E + + R EE K+ E
Sbjct: 829 E-EEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 887
Query: 275 EVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPS 312
EV+ ++ QR + Q++ +PS
Sbjct: 888 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPS 925
Score = 64.3 bits (155), Expect = 3e-10
Identities = 49/160 (30%), Positives = 88/160 (55%), Gaps = 14/160 (8%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEE---RKKALDERLR 205
+L++ E A+ ++ +A + KR E+ K++EELR+++E R++ +ER R
Sbjct: 725 QLQQLEKAKAAKLEQERREAEMRAKREEEER-----KRQEELRRQQEEILRRQQEEERKR 779
Query: 206 FEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEE 265
E+E E R++QEE RR RE+E + R +++ + EEA RRL+E+ + R ++E
Sbjct: 780 REEE--ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 837
Query: 266 ETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASA 305
E ++K E EEAA + + R + + R+ +A
Sbjct: 838 EL-LRKQE---EEAAKWAREEEEAQRRLEENRLRMEEEAA 873
Score = 50.4 bits (119), Expect = 5e-06
Identities = 42/119 (35%), Positives = 67/119 (56%), Gaps = 25/119 (21%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEEL------------RKEEER 196
R RE+E + Q+ +A ++ RE+ E+ +K+EEL R+EEE
Sbjct: 806 RQREEEERQ------QQEEALRRLEERRREE--EERRKQEELLRKQEEEAAKWAREEEEA 857
Query: 197 KKALDE-RLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQ 254
++ L+E RLR E+E R E+EER+R+ E ++Q E R++QQ +EA RRL++Q
Sbjct: 858 QRRLEENRLRMEEEAARL-RHEEEERKRKELEVQRQKELMRQRQQ---QQEALRRLQQQ 912
Score = 35.8 bits (81), Expect = 0.13
Identities = 36/188 (19%), Positives = 83/188 (44%), Gaps = 40/188 (21%)
Query: 151 REDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEE----RKKALDERLRF 206
+++E A ++ +E R+ E+ + + EEE RK +E R+K L + +
Sbjct: 842 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 901
Query: 207 EQERMEQERQEQEER---------------------------------ERRYREREQQIE 233
+QE + + +Q+Q+++ ++ ERE+Q+
Sbjct: 902 QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLR 961
Query: 234 EHRRKQQ--TLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPR 291
E +R+QQ ++A + +++ ++Q + G + + + KS E+++ A Q+ +
Sbjct: 962 EEQRRQQRELMKALQQQQQQQQQKLSG-WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
Query: 292 EFFKQQER 299
+ +Q R
Sbjct: 1021 QQHQQPNR 1028
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 66.6 bits (161), Expect = 7e-11
Identities = 47/158 (29%), Positives = 78/158 (49%), Gaps = 21/158 (13%)
Query: 175 INREQFWEQAKKEEE----LRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQ 230
+ R+Q E+ ++EEE ++EE ++ ++ + ++R E+ERQ+QEE RR ER +
Sbjct: 769 LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRR 828
Query: 231 QIEEHRRKQQTL-------------EAEEAKRRLKEQSIFGDH---RDEEEETHMKKSES 274
+ EE RRKQ+ L E EEA+RRL+E + + R EE K+ E
Sbjct: 829 E-EEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 887
Query: 275 EVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPS 312
EV+ ++ QR + Q++ +PS
Sbjct: 888 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPS 925
Score = 64.3 bits (155), Expect = 3e-10
Identities = 49/160 (30%), Positives = 88/160 (55%), Gaps = 14/160 (8%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEE---RKKALDERLR 205
+L++ E A+ ++ +A + KR E+ K++EELR+++E R++ +ER R
Sbjct: 725 QLQQLEKAKAAKLEQERREAEMRAKREEEER-----KRQEELRRQQEEILRRQQEEERKR 779
Query: 206 FEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEE 265
E+E E R++QEE RR RE+E + R +++ + EEA RRL+E+ + R ++E
Sbjct: 780 REEE--ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 837
Query: 266 ETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASA 305
E ++K E EEAA + + R + + R+ +A
Sbjct: 838 EL-LRKQE---EEAAKWAREEEEAQRRLEENRLRMEEEAA 873
Score = 50.4 bits (119), Expect = 5e-06
Identities = 42/119 (35%), Positives = 67/119 (56%), Gaps = 25/119 (21%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEEL------------RKEEER 196
R RE+E + Q+ +A ++ RE+ E+ +K+EEL R+EEE
Sbjct: 806 RQREEEERQ------QQEEALRRLEERRREE--EERRKQEELLRKQEEEAAKWAREEEEA 857
Query: 197 KKALDE-RLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQ 254
++ L+E RLR E+E R E+EER+R+ E ++Q E R++QQ +EA RRL++Q
Sbjct: 858 QRRLEENRLRMEEEAARL-RHEEEERKRKELEVQRQKELMRQRQQ---QQEALRRLQQQ 912
Score = 35.8 bits (81), Expect = 0.13
Identities = 36/188 (19%), Positives = 83/188 (44%), Gaps = 40/188 (21%)
Query: 151 REDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEE----RKKALDERLRF 206
+++E A ++ +E R+ E+ + + EEE RK +E R+K L + +
Sbjct: 842 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 901
Query: 207 EQERMEQERQEQEER---------------------------------ERRYREREQQIE 233
+QE + + +Q+Q+++ ++ ERE+Q+
Sbjct: 902 QQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLR 961
Query: 234 EHRRKQQ--TLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPR 291
E +R+QQ ++A + +++ ++Q + G + + + KS E+++ A Q+ +
Sbjct: 962 EEQRRQQRELMKALQQQQQQQQQKLSG-WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQ 1020
Query: 292 EFFKQQER 299
+ +Q R
Sbjct: 1021 QQHQQPNR 1028
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 66.2 bits (160), Expect = 9e-11
Identities = 44/142 (30%), Positives = 70/142 (49%), Gaps = 11/142 (7%)
Query: 169 AVEMKRINREQFWEQAKKEEELRK--EEERKKALDERLRFEQERMEQERQEQEERERRYR 226
A+EM+ R+ + K + K EEE+ K ER E+ER E+ER+ + ERERR R
Sbjct: 266 AIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRER 325
Query: 227 EREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDH---------RDEEEETHMKKSESEVE 277
ERE++ E R K++ E E + R ++++ D RD E + K S
Sbjct: 326 EREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSR 385
Query: 278 EAAAIIAQRPDNPREFFKQQER 299
E + + + RE +++ER
Sbjct: 386 EKSRDRERERERERERERERER 407
Score = 51.2 bits (121), Expect = 3e-06
Identities = 50/220 (22%), Positives = 96/220 (43%), Gaps = 38/220 (17%)
Query: 116 VNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRI 175
+NA +E+ I + +S R + L + ++++ + + ++ + E +R
Sbjct: 264 INAIEMEEDKRDLISREISK--FRDTHKKLEEEKGKKEKERQEIEKERRERERERERERE 321
Query: 176 NREQFWEQAK-KEEELRKEEERKKALD---ERLRFEQERMEQERQEQEERER-------- 223
RE+ E+ + +E E KE ER++ D +R + ++ER +RER
Sbjct: 322 RREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDR 381
Query: 224 ---------------RYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETH 268
R RERE++ E R +++ E E + R +E+ D ++EE+ +
Sbjct: 382 SRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAY 441
Query: 269 -MKKSESEVEEAAAIIAQRPDN--------PREFFKQQER 299
+K E ++ E A +R N RE+ K+ ER
Sbjct: 442 ERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAER 481
Score = 47.0 bits (110), Expect = 5e-05
Identities = 29/120 (24%), Positives = 60/120 (50%), Gaps = 4/120 (3%)
Query: 182 EQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERE-RRYREREQQIEEHRRKQQ 240
++++ E+ R E ++ ER R + E+ER+ + ERE R RE++++ + ++
Sbjct: 380 DRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEED 439
Query: 241 TLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERV 300
E + +R+L+E+ R + E +K E E+ A + + RE K+ +R+
Sbjct: 440 AYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEA---EREEERRREMAKEAKRL 496
Score = 46.2 bits (108), Expect = 9e-05
Identities = 32/137 (23%), Positives = 66/137 (48%), Gaps = 7/137 (5%)
Query: 164 QKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERER 223
+ +D + R + + ++E E +E ER++ + E+ER E+ER+ +++++R
Sbjct: 373 RSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERER-EREREREKDKKR 431
Query: 224 RYREREQQIEEHRRKQQTLEAEEA--KRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAA 281
E E+ E R+ ++ L +EA + RLK I R+ ++ +K EE
Sbjct: 432 DREEDEEDAYERRKLERKLREKEAAYQERLKNWEI----RERKKTREYEKEAEREEERRR 487
Query: 282 IIAQRPDNPREFFKQQE 298
+A+ +EF + +
Sbjct: 488 EMAKEAKRLKEFLEDYD 504
Score = 44.3 bits (103), Expect = 4e-04
Identities = 43/181 (23%), Positives = 75/181 (41%), Gaps = 34/181 (18%)
Query: 147 RLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRF 206
R R RE E + + DA E +++ R+ ++A +E L+ E R++
Sbjct: 419 REREREREKDKKRDREEDEEDA-YERRKLERKLREKEAAYQERLKNWEIRERKKTREYEK 477
Query: 207 EQERMEQERQEQEERERRY----------------------------REREQQIEEHRRK 238
E ER E+ R+E + +R RE+E + +E RK
Sbjct: 478 EAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRK 537
Query: 239 QQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQE 298
++ E EE ++RL + H D + E + E+E I Q P++ E ++QE
Sbjct: 538 REKEELEEIRQRLLAEG----HPDPDAELQRMEQEAE-RRRQPQIKQEPESEEEEEEKQE 592
Query: 299 R 299
+
Sbjct: 593 K 593
Score = 43.9 bits (102), Expect = 5e-04
Identities = 34/142 (23%), Positives = 66/142 (46%), Gaps = 5/142 (3%)
Query: 153 DENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERME 212
D N + + + D E +R + + ++E E +E ER++ ER R + ++ +
Sbjct: 376 DRNKDRSRSREKSRDRERERERERERERERERERERERERERERER---EREREKDKKRD 432
Query: 213 QERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGD-HRDEEEETHMKK 271
+E E++ ERR ER+ + E+ Q+ L+ E + R K + + R+EE M K
Sbjct: 433 REEDEEDAYERRKLERKLR-EKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAK 491
Query: 272 SESEVEEAAAIIAQRPDNPREF 293
++E D+P+ +
Sbjct: 492 EAKRLKEFLEDYDDDRDDPKYY 513
Score = 38.5 bits (88), Expect = 0.020
Identities = 39/168 (23%), Positives = 71/168 (42%), Gaps = 36/168 (21%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQ 208
+LRE E A YQ+ E++ + + +E+ + EE R+ E K+A +RL+
Sbjct: 449 KLREKEAA------YQERLKNWEIRERKKTREYEKEAEREEERRREMAKEA--KRLKEFL 500
Query: 209 ERMEQERQEQE-------ERERRYREREQQIEEHRRKQQTLEAEEAKRRL---------- 251
E + +R + + ++ R RE+E + +E RK++ E EE ++RL
Sbjct: 501 EDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDA 560
Query: 252 -----------KEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPD 288
+ Q + EEE K+ + E E + P+
Sbjct: 561 ELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPE 608
Score = 35.4 bits (80), Expect = 0.17
Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
Query: 142 SPVLHRLRLREDE-NAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKAL 200
S + RLR RE E A+ +K + +R+ E + + + + +E ER++
Sbjct: 516 SALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQP 575
Query: 201 DERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTL 242
+ E E E+E+QE+EE+ E E++ E+ + TL
Sbjct: 576 QIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTL 617
Score = 31.2 bits (69), Expect = 3.1
Identities = 22/92 (23%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query: 213 QERQEQEERERRYRERE-QQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKK 271
++ ++ E E+ +E+E Q+IE+ RR+++ E +RR +E+ + E+E+ ++
Sbjct: 285 RDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERE 344
Query: 272 SESEVEEAAAIIAQRPDNPREFFKQQERVASA 303
E + + R D RE + ++R S+
Sbjct: 345 RERDRDRDRTKERDR-DRDRERDRDRDRERSS 375
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 65.5 bits (158), Expect = 1e-10
Identities = 42/185 (22%), Positives = 91/185 (49%), Gaps = 12/185 (6%)
Query: 164 QKTDAAVEMKRINREQFWEQ--------AKKEEELRKEEERKKALDERLRFEQERMEQER 215
++++A + + +Q EQ A++++ + +++E+++ L+E+ R E+E Q+
Sbjct: 365 ERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQE 424
Query: 216 QEQEERERRYREREQQIEEHRRKQQTLE-AEEAKRRLKEQSIFGDHRDEEEETHMKKSES 274
+EQ RE+ + R +++E R++++ AEE KRR++ + + + EEE+ H++ +
Sbjct: 425 REQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQ 484
Query: 275 EVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIP 334
++ + A++ P QQ PS P +H + R P+
Sbjct: 485 QLLQEQAMLLHDHRRPHPQHSQQPPPPQQERSK---PSFHAPEPKAHYEPADRAREVPVR 541
Query: 335 TRSPS 339
T S S
Sbjct: 542 TTSRS 546
Score = 58.2 bits (139), Expect = 2e-08
Identities = 68/257 (26%), Positives = 110/257 (42%), Gaps = 48/257 (18%)
Query: 182 EQAKKEEELRKEEERKKAL--DERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQ 239
+Q +E++LR++EE K+ L + + R EQ++ ++ R E+++R R R+Q+ E+ RR+Q
Sbjct: 373 QQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQ 432
Query: 240 QTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVE-EAAAIIAQRPDNPREFFKQQE 298
E KRRL+E + ++EEE ++ + VE E I Q + R Q+
Sbjct: 433 ------EEKRRLEE--LERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQ 484
Query: 299 RVASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDE 358
++ A L HRR P P S P Q ER+
Sbjct: 485 QLLQEQA--------------MLLHDHRR----PHPQHS-------QQPPPPQQERSKPS 519
Query: 359 VTSSQPPPLPPPPPPAQE----TQEPSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGP 414
+ +P P A+E T SP+L +R +P +G +QA R
Sbjct: 520 FHAPEPKAHYEPADRAREVPVRTTSRSPVL----SRRDSPLQGSGQQ----NSQAGQRNS 571
Query: 415 GSPAEDLMFMESAEQAV 431
S E + E E+ V
Sbjct: 572 TSSIEPRLLWERVEKLV 588
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 65.5 bits (158), Expect = 1e-10
Identities = 62/268 (23%), Positives = 121/268 (45%), Gaps = 19/268 (7%)
Query: 173 KRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERE-RRYREREQQ 231
K + +EQ E+ K+ E+ R+ ++ K+ E+ + +Q ME+ER++++E+E R +E+E++
Sbjct: 517 KELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKE 576
Query: 232 IEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPR 291
+++ + +++ E E+ + +L+E+ + R+ E ++K ESE + + P R
Sbjct: 577 LQKMKEQEKECELEKEREKLEEKI---EPREPNLEPMVEKQESE---NSCNKEEEPVFTR 630
Query: 292 EFFKQQERVASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQ 351
+ + E+ A+ + S RP L + + +P R +Q
Sbjct: 631 QDSNRSEKEATPVVHETEPESGSQPRPAV-LSGYFKQFQKSLPPRFQRQQEQMKQQQWQQ 689
Query: 352 IER--ALDEVTSSQPPPLPPPPPPAQETQEPSPILDSE------ETRAAAPQAWAGP--M 401
++ L + SQP PPPP + +P + R Q++ P M
Sbjct: 690 QQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMM 749
Query: 402 EEPPQAQAPPRGPGS-PAEDLMFMESAE 428
P PP PG P + LM + E
Sbjct: 750 SGRPAMDIPPIHPGMIPPKPLMRRDQME 777
Score = 40.0 bits (92), Expect = 0.007
Identities = 93/434 (21%), Positives = 150/434 (34%), Gaps = 56/434 (12%)
Query: 209 ERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETH 268
E + +++Q++ + E R ++ EQ I+ +K + +L + +++ T
Sbjct: 1683 EVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFA------KKQATG 1736
Query: 269 MKKSESEVEEAAAIIAQRPDN-----PREFFKQQERVASASAGSCDVPSPFNHRPGSHLD 323
+++++S A P + P + S P P +
Sbjct: 1737 IQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLAS 1796
Query: 324 SHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEPS-- 381
+ + +P+ S S S +AS P + A +SS P P P P P+
Sbjct: 1797 TSAPVPASPLAPVSASASVSASVPASTS---AAAITSSSAPASAPAPTPILASVSTPASV 1853
Query: 382 PILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPATA 441
IL S A + P A + P P V+ AP PA+A
Sbjct: 1854 TILASASIPILASALASTSAPTPAPAASSPAAP----------------VITAPTIPASA 1897
Query: 442 DATEIHDAADTIETDTATADTTVANNVP----PAATSLIDLWPGNGEGASTLQGEPRAPT 497
+ A + A A T V+ P PA T P +T Q +
Sbjct: 1898 PTASV-PLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQ--- 1953
Query: 498 PPSGTEVTLAEVPL-LDEVAPEPLL--PAGEGCATLLNFDELPEPPATFCDPEEVEGEPL 554
PP + A+ P D VA + P G T +D PPA D + G P+
Sbjct: 1954 PPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLG-PI 2012
Query: 555 AAPQTPTLPSALEEL---------EQEQEPEPHLLTNGETTQKEGTQASEGYFSQSQEEE 605
+ PQ P++ + + L E + + L G T + G AS G E
Sbjct: 2013 SPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNG---NENEVV 2069
Query: 606 FAQSEELCAKAPPP 619
SE+ K P P
Sbjct: 2070 PVLSEKSADKIPEP 2083
Score = 37.7 bits (86), Expect = 0.033
Identities = 40/180 (22%), Positives = 65/180 (36%), Gaps = 20/180 (11%)
Query: 269 MKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGSHLDSHRRM 328
+++ E + ++ I + P + +K + S + N RP RR
Sbjct: 960 IERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPV------RRS 1013
Query: 329 APT--PIPTRSPSDSSTASTPVAEQIERALDEVT--------SSQPPPLPPPPPPA--QE 376
P P+ + E+ E+ ++V PPP PPP PPA Q
Sbjct: 1014 GPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQP 1073
Query: 377 TQEPSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPV 436
P PI E + A ++P Q P P S + +++ Q +AAPV
Sbjct: 1074 QSVPPPIQPEAEKFPSTETATLA--QKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPV 1131
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 65.1 bits (157), Expect = 2e-10
Identities = 41/155 (26%), Positives = 84/155 (54%), Gaps = 8/155 (5%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKK---EEELRKEEERKKALDERLR 205
++RE+E E + +K E R E+ WEQ +K +EE E+E K E
Sbjct: 13 KMREEE--EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 70
Query: 206 FEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEE 265
+EQ+R+ +++++ E++ R RE+E+++ E + QQ + E K+ +E+ + + +E+
Sbjct: 71 WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQ 130
Query: 266 ETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERV 300
E M + E +++E + ++ + RE Q+E++
Sbjct: 131 EEMMWEQEEKMQEQEEKMWEQEEKMRE---QEEKM 162
Score = 53.1 bits (126), Expect = 8e-07
Identities = 32/123 (26%), Positives = 68/123 (55%), Gaps = 7/123 (5%)
Query: 177 REQFWEQAKKEEELRKEEERKKALDERLRFEQERM-EQERQEQEERERRYREREQQIEEH 235
RE+ + ++EE +R++EE+ + +E++R ++E+M EQE + QE+ E+ + + E+ E+
Sbjct: 8 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67
Query: 236 RRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFK 295
+ + E K ++ EQ D R E+E M+ E ++ + + ++ E +
Sbjct: 68 EKMWEQQRLPEQKEKMWEQ----DERLREKEERMR--EQKMWQQVEKMREKKKTQEEKMQ 121
Query: 296 QQE 298
+QE
Sbjct: 122 EQE 124
Score = 52.8 bits (125), Expect = 1e-06
Identities = 37/139 (26%), Positives = 74/139 (53%), Gaps = 12/139 (8%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKAL---DERLR 205
++RE E E + +K E E+ WEQ +K E ++ E+K+ + DERLR
Sbjct: 34 KMREQE--EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLR 91
Query: 206 FEQERMEQERQEQE-----ERERRYREREQQIEEHRRKQQTL--EAEEAKRRLKEQSIFG 258
++ERM +++ Q+ E+++ E+ Q+ EE ++Q+ + E EE + +E+
Sbjct: 92 EKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQ 151
Query: 259 DHRDEEEETHMKKSESEVE 277
+ + E+E M++ E +++
Sbjct: 152 EEKMREQEEKMREQEEKMQ 170
Score = 50.1 bits (118), Expect = 6e-06
Identities = 27/118 (22%), Positives = 69/118 (58%), Gaps = 6/118 (5%)
Query: 185 KKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRK--QQTL 242
++EE +R+ E++ + +E +R ++E+M+++ ++ E+E + E+E++++E K +Q
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
Query: 243 EAEEAKRRLKEQSIFGDHRDE--EEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQE 298
+ E + ++ EQ + +++ E++ +++ E + E + Q+ + RE K QE
Sbjct: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQK--MWQQVEKMREKKKTQE 117
Score = 49.7 bits (117), Expect = 8e-06
Identities = 30/147 (20%), Positives = 86/147 (58%), Gaps = 17/147 (11%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQ 230
E ++ RE+ ++EE+++++EE+ + +E++ ++E+M+++ ++ E+E + E+E+
Sbjct: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 68
Query: 231 QIEEHRR----KQQTLEAEEAKR----RLKEQSIFGD-----HRDEEEETHMKKSESEVE 277
++ E +R K++ E +E R R++EQ ++ + + +E M++ E +++
Sbjct: 69 KMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQ 128
Query: 278 EAAAIIAQRPDNPRE----FFKQQERV 300
E ++ ++ + +E ++Q+E++
Sbjct: 129 EQEEMMWEQEEKMQEQEEKMWEQEEKM 155
Score = 49.7 bits (117), Expect = 8e-06
Identities = 36/159 (22%), Positives = 84/159 (52%), Gaps = 26/159 (16%)
Query: 147 RLRLREDENAEPVGTTYQKTDAAVEMKRI--NREQFWEQ----AKKEEELRKEE------ 194
+++ +E++ E +++ + E +R+ +E+ WEQ +KEE +R+++
Sbjct: 48 KMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVE 107
Query: 195 ---ERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRL 251
E+KK +E+++ ++E+M+++ + E+E + +E+E+++ E K + +E K R
Sbjct: 108 KMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEK---MREQEEKMRE 164
Query: 252 KEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNP 290
+E+ + G EE+ ++ + E E + DNP
Sbjct: 165 QEEKMQG---QEEKMRDVEPAGGEAGEGSP-----QDNP 195
Score = 36.6 bits (83), Expect = 0.074
Identities = 23/90 (25%), Positives = 50/90 (55%), Gaps = 5/90 (5%)
Query: 215 RQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIF--GDHRDEEEETHMKKS 272
R+E+ RER + RE++ E R +++ ++ +E K R +E+ ++ + E+EE ++
Sbjct: 2 REEERMREREKKMREEE-EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
Query: 273 ESEVEEAAAIIAQR--PDNPREFFKQQERV 300
E E+ + Q+ P+ + ++Q ER+
Sbjct: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERL 90
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 65.1 bits (157), Expect = 2e-10
Identities = 59/240 (24%), Positives = 110/240 (45%), Gaps = 34/240 (14%)
Query: 97 ACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRL-------- 148
A S A +++ + ++ +V S E + Q+L L +L + L
Sbjct: 97 ALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGP 156
Query: 149 ----RLREDEN-----AEPVGTTYQKTDAAVE----MKRINREQFWEQAKKEEELRKEEE 195
+L+++ N E VG Q A VE + +NR Q ++EE LR++EE
Sbjct: 157 SKVEQLQDETNHLRKELESVGRQLQ---AEVENNQMLSLLNRRQEERLREQEERLREQEE 213
Query: 196 RKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRK--QQTLEAEEAKRRLKE 253
R + +ERL ++ER+ ++ + E+E R E+E+++ EH + +Q E + RL+E
Sbjct: 214 RLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLRE 273
Query: 254 QSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPRE----FFKQQERVASASAGSCD 309
Q + R E+E + + E + E + ++ + RE +Q+ER+ C+
Sbjct: 274 Q----EERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCE 329
Score = 55.5 bits (132), Expect = 2e-07
Identities = 43/143 (30%), Positives = 73/143 (51%), Gaps = 6/143 (4%)
Query: 147 RLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRF 206
RLR +E+ E + + E + EQ ++EE L ++EER +ERLR
Sbjct: 235 RLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLRE 294
Query: 207 EQERM---EQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKE-QSIFGDHRD 262
++ER+ E+ +EQEER ER ++ EE +Q+ L +E R L+E + + R
Sbjct: 295 QEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQE--RLLEEVEKLLEQERR 352
Query: 263 EEEETHMKKSESEVEEAAAIIAQ 285
+EE+ + + E +EE ++ Q
Sbjct: 353 QEEQERLLERERLLEEVEELLEQ 375
Score = 53.9 bits (128), Expect = 4e-07
Identities = 43/160 (26%), Positives = 76/160 (47%), Gaps = 17/160 (10%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQ 208
RLRE E +++ + E + REQ ++EE LR++EER +ERLR ++
Sbjct: 270 RLREQEER-----LHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQE 324
Query: 209 ERM-EQERQEQEER-----------ERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSI 256
ER+ EQE+ +ER ERR E+E+ +E R ++ E E +R ++
Sbjct: 325 ERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDER 384
Query: 257 FGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQ 296
+E +++ E +E + ++ PR F++
Sbjct: 385 LWQQETLQELERLRELERMLELGWEALYEQRAEPRSGFEE 424
Score = 51.6 bits (122), Expect = 2e-06
Identities = 40/142 (28%), Positives = 71/142 (50%), Gaps = 14/142 (9%)
Query: 147 RLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRF 206
RLR E+ E ++ + E + EQ ++EE LR++EER +ERLR
Sbjct: 249 RLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLRE 308
Query: 207 EQERM---EQERQEQEER----------ERRYREREQQIEEHRRKQQTLEAEEAKRRLKE 253
++ER+ E+ +EQEER ER E E+ +E+ RR+++ E +R L+E
Sbjct: 309 QEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEE 368
Query: 254 -QSIFGDHRDEEEETHMKKSES 274
+ + R +++ + + E+
Sbjct: 369 VEELLEQERLRQQDERLWQQET 390
Score = 50.8 bits (120), Expect = 4e-06
Identities = 40/146 (27%), Positives = 73/146 (50%), Gaps = 15/146 (10%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKK--EEELR--KEEERKKALDERL 204
RLRE E ++ E R E+ EQ ++ E+E R ++EER +ERL
Sbjct: 200 RLREQE---------ERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERL 250
Query: 205 RFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEE 264
R +ER+ ++ + E+E R RE+E+++ H ++++ E EE R +E+ + R E
Sbjct: 251 REHEERLCEQEERLCEQEERLREQEERL--HEQEERLCEQEERLREQEERLCEQEERLRE 308
Query: 265 EETHMKKSESEVEEAAAIIAQRPDNP 290
+E + + E + E + ++ P
Sbjct: 309 QEERLCEQEERLREQEERLCEQEKLP 334
Score = 49.7 bits (117), Expect = 8e-06
Identities = 48/148 (32%), Positives = 74/148 (50%), Gaps = 20/148 (13%)
Query: 147 RLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRF 206
RLR +E+ E ++ + E + REQ EE LR++EER +ERLR
Sbjct: 200 RLREQEERLREQEERLREQEERLCEQEERLREQ-------EERLREQEERLCEQEERLRE 252
Query: 207 EQERM-EQERQ--EQEER--ERRYREREQQ----IEEHRRKQQTLEAEEAKRRLKEQSIF 257
+ER+ EQE + EQEER E+ R EQ+ +E R ++Q E + RL+EQ
Sbjct: 253 HEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQ--- 309
Query: 258 GDHRDEEEETHMKKSESEVEEAAAIIAQ 285
+ R E+E +++ E + E + Q
Sbjct: 310 -EERLCEQEERLREQEERLCEQEKLPGQ 336
Score = 33.9 bits (76), Expect = 0.48
Identities = 43/161 (26%), Positives = 73/161 (45%), Gaps = 23/161 (14%)
Query: 147 RLRLREDENAEPVGTTYQKTDAAVEMKRI-NREQFWEQAKK--EEELRKEE-----ERKK 198
RLR +E+ E ++ + E +++ +E+ E+ +K E+E R+EE ER++
Sbjct: 305 RLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERER 364
Query: 199 ALDE--------RLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRR 250
L+E RLR + ER+ Q+ QE R ER ++ +Q E
Sbjct: 365 LLEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQRAEPRSGFEE 424
Query: 251 LKEQSIFGDHRDEEEETHMKKS----ESEVEEAAAIIAQRP 287
L ++ + E++ +KKS E E+AA A RP
Sbjct: 425 LNNEN-KSTLQLEQQVKELKKSGGAEEPRGSESAA--AARP 462
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 65.1 bits (157), Expect = 2e-10
Identities = 110/491 (22%), Positives = 172/491 (35%), Gaps = 106/491 (21%)
Query: 186 KEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAE 245
+E+E E+E++ R + + ++ER + + + R+ + + EE ++ + + E
Sbjct: 919 EEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDE 978
Query: 246 EAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASA 305
E +E D EE K E+EV + E S S+
Sbjct: 979 EDDEEDEEDE------DREEAVDTTKKETEVSDG------------------EDEESDSS 1014
Query: 306 GSCDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVTSSQPP 365
C + + + S DS + + + S S SS++S+ +E DE +P
Sbjct: 1015 SKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSE--DEEEEERPA 1072
Query: 366 PLPPPPPPAQETQEPSP----------ILDSEET----RAAAPQAWAGPMEE-PPQA--- 407
LP PP +E P+P + S T + A+P AGP EE PP A
Sbjct: 1073 ALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLR 1132
Query: 408 -QAPPRGPGSPAEDLMFMESAEQAVLAAPVEPATADATEIHDAADTIETDTATADTT--- 463
PP GP +PA S+ +L P + + + E AT
Sbjct: 1133 PPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFP 1192
Query: 464 -------------VANNVPPAATSLIDLWP----------GNGEGASTLQGEPRAPTPPS 500
N+P SL+ WP G G T + E
Sbjct: 1193 GPASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAE-----P 1247
Query: 501 GTEV---TLAEVPLLDEVAPEPLLPAGEGCATLLNFDEL--------------------- 536
GTEV LA++ L P LPA E DE
Sbjct: 1248 GTEVDLAVLADLALTPARRGLPALPAVEDSEATETSDEAERPRPLLSHILLEHNYALAVK 1307
Query: 537 PEPPATFCDPEEVEGEPLA---APQTPTLPSALEELEQEQEPEPHLLTNGETTQKEGTQA 593
P PPA P E P A +P L + + + +EP+P L + ++EG +
Sbjct: 1308 PTPPAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEEPKPQQL---QQQREEGEEE 1364
Query: 594 SEGYFSQSQEE 604
E + +EE
Sbjct: 1365 GEEEGEEEEEE 1375
Score = 43.9 bits (102), Expect = 5e-04
Identities = 74/354 (20%), Positives = 117/354 (33%), Gaps = 50/354 (14%)
Query: 260 HRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFN---- 315
++D H S + + AI A +S+S+ S S F
Sbjct: 305 YQDAFSRRHFSASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSSSQFRSSDA 364
Query: 316 HRPGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPP---- 371
+ P + +R T P R + P AE +S PP P P
Sbjct: 365 NYPAYYESWNRYQRHTSYPPRRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQD 424
Query: 372 --PPAQETQEPSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPA----------- 418
PPA E P P P + P+ +P R GSPA
Sbjct: 425 YRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARS-GSPAPETTNESVPFA 483
Query: 419 ---------EDLMFMESAEQAVLAAPVEPATADATEIHDAADTIETDTATADTTVANNVP 469
E L+ + ++ + LA+ E +++ + A DT ++ + P
Sbjct: 484 QHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDT-GSEVPSGSGHGPCTPP 542
Query: 470 PAATSLIDLWP-GNGEGASTLQ-----GEPRAPTPPSGTEVTLAEVPLLDEVAPEPLLPA 523
PA + D+ P G+GE +T + G+ +A SG ++ +++ P P P
Sbjct: 543 PAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQ 602
Query: 524 GEGCATLLNFDELPEPPATFCDPEEVEGEPLAAPQTPTLPSALEELEQEQEPEP 577
P PP P + PL P P P+ L + P P
Sbjct: 603 ----------QPPPPPPPPPPPPPYLASLPLGYP--PHQPAYLLPPRPDGPPPP 644
Score = 33.9 bits (76), Expect = 0.48
Identities = 61/273 (22%), Positives = 95/273 (34%), Gaps = 48/273 (17%)
Query: 326 RRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQ------- 378
+R P+ I S STP E + E + +P PP E +
Sbjct: 896 KRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKH 955
Query: 379 EPSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEP 438
S LDSE A+ + E+ + + ED E E+AV E
Sbjct: 956 RKSFALDSEGEEASQESSSEKDEEDDEEDE----------ED----EDREEAVDTTKKET 1001
Query: 439 ATADATEIHD--------AADTIETDTATADTTVANNVPPAATSLIDLWPGNGEGASTLQ 490
+D + AD+ + +T+D+ +++ +++S + +S
Sbjct: 1002 EVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESS 1061
Query: 491 GE-----------PRAPTPPSGTEVTL---AEVPLLDEVAPEPLLPAGEGCATLLN---- 532
E P A PP V EVP+ + VA P+ P E A+
Sbjct: 1062 SEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGP 1121
Query: 533 FDELPEPPATFCDPEEVEGEPLAAPQTPTLPSA 565
+E P P A PE G P AP+ PS+
Sbjct: 1122 TEESP-PSAPLRPPEPPAGPPAPAPRPDERPSS 1153
Score = 32.0 bits (71), Expect = 1.8
Identities = 41/183 (22%), Positives = 58/183 (31%), Gaps = 18/183 (9%)
Query: 234 EHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHM----KKSESEVEEAAAIIAQRPDN 289
+H +E ++R K + D +EEE + M + + SEV + P
Sbjct: 484 QHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSG---HGPCT 540
Query: 290 PREFFKQQERVASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPI-PTRSPSDSSTASTPV 348
P E VA +G PG+ +S + P S D +
Sbjct: 541 PPPAPANFEDVAPTGSGE----------PGATRESPKANGQNQASPCSSGDDMEISDDDR 590
Query: 349 AEQIERALDEVTSSQPPPLPPPPPPAQETQEPSPILDSEETRAAAPQAWAGPMEEPPQAQ 408
A PPP PPPPPP P + P+ P E P
Sbjct: 591 GGSPPPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPP 650
Query: 409 APP 411
PP
Sbjct: 651 PPP 653
Score = 31.2 bits (69), Expect = 3.1
Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Query: 339 SDSSTASTPVAEQIERAL-DEVTSSQPPPLPPPPPP 373
SDSS++S R+L +PPP PPPPPP
Sbjct: 1377 SDSSSSSDGEGALRRRSLRSHARRRRPPPPPPPPPP 1412
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 64.7 bits (156), Expect = 3e-10
Identities = 88/382 (23%), Positives = 141/382 (36%), Gaps = 43/382 (11%)
Query: 158 PVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQE 217
P ++ A VE + Q EE +EE R+ L + E E Q
Sbjct: 400 PAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQS 459
Query: 218 QEERERRYREREQQIEEHRRKQQTLEAEEAKRRL---KEQSIFGDHRDEE----EETHMK 270
+E E +I+ + + A+ R +E S H + + EET +
Sbjct: 460 PLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAE 519
Query: 271 KSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGSHLDSHRRMAP 330
++ +E++ AAI A + P E SA +V SP G ++ AP
Sbjct: 520 EASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSP--SAKGVSIEE----AP 573
Query: 331 TPIPTRSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPP----------PPPAQETQEP 380
+ S +++ A Q+ A + P + PP PPPA+E
Sbjct: 574 LELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 633
Query: 381 SPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPAT 440
+EE A + P EE P PP +PAE + AE+A A V+
Sbjct: 634 VQPPPAEE---APAEVQPPPAEEAPAEVQPPPAEEAPAE--VQPPPAEEA--PAEVQSLP 686
Query: 441 ADATEIHDAADTIET----DTATADTTVANNVPPAATSLIDLWPGNGEGASTLQGEPRAP 496
A+ T I + + + D + +V + PPA L + +P GE A
Sbjct: 687 AEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFP---------IGEASAE 737
Query: 497 TPPSGTEVTLAEVPLLDEVAPE 518
P +E T + L++ V+ E
Sbjct: 738 VSPPPSEQTPEDEALVENVSTE 759
Score = 57.8 bits (138), Expect = 3e-08
Identities = 124/555 (22%), Positives = 196/555 (35%), Gaps = 99/555 (17%)
Query: 143 PVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQ--FWEQAKKEEELRKEEERKKAL 200
P + ++L+ D + + T Y ++++++EQ ++ +++ R + K+
Sbjct: 119 PNIPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSK 178
Query: 201 DERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDH 260
++ L+ + + E + E + R T E ++ L E D
Sbjct: 179 EDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVLLE-----DE 233
Query: 261 RDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRPGS 320
EE + + S V++ A+ + P + K Q + + + P P
Sbjct: 234 LREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAE-PRPAE----- 287
Query: 321 HLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPP--------- 371
++H ++ P ST TP AE + QPPP P
Sbjct: 288 --ETHVQVQP-----------STEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQ 334
Query: 372 PPAQETQEPSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLM---FMESAE 428
PP+ E + PS L +E P A P EEPP PP SP+ +L+ SA+
Sbjct: 335 PPSAE-ESPSVELLAE---ILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQ 390
Query: 429 QAVL--------------AAPVEPATADAT---------EIHDAADTIETDTATADTTVA 465
+A + A VEP T + T E + E +TA T A
Sbjct: 391 KAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPA 450
Query: 466 NNVPPAATSLIDLWPGNGEGASTLQ----GEPRAPTPPSGTEVTLAEVPLLDEVAPEPLL 521
P S + E ++ +Q EP A P+ L+E +E E
Sbjct: 451 EEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQS 510
Query: 522 PAGEGCAT--------LLNFDELP--EPPATFCDPEEVEGEPLAAPQTPTLPSA----LE 567
P E LL E P E PA P E AP PSA +E
Sbjct: 511 PLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIE 570
Query: 568 ELEQEQEPEPHLLTNGETTQKEGTQASEGYFSQSQEEEFAQSEELCAKAPPPVFYNKPPE 627
E E +P +GE T E A+ + ++ A +EE A+ PP P E
Sbjct: 571 EAPLELQP-----PSGEETTAEEASAAIQLLAATE----ASAEEAPAEVQPPPAEEAPAE 621
Query: 628 IDITCWDADPVPEEE 642
+ P P EE
Sbjct: 622 V-------QPPPAEE 629
Score = 47.8 bits (112), Expect = 3e-05
Identities = 118/526 (22%), Positives = 183/526 (34%), Gaps = 75/526 (14%)
Query: 170 VEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEE--RERRYRE 227
+ K I+R F ++ KK + E+E ++ + + E +++ + E ++
Sbjct: 208 IGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPA 267
Query: 228 REQQ--IEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQ 285
+ Q +EE K + AEE ++ Q + D E T + ++ +V+ A A
Sbjct: 268 KIQPPLVEEATAKAEPRPAEET--HVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAP 325
Query: 286 RPDNPREFFKQQ-------ERVASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPTRSP 338
+ P E E +A S + SP P L +P+
Sbjct: 326 LVEFPAEIQPPSAEESPSVELLAEILPPSAE-ESPSEEPPAEILPPPAEKSPSVELLGEI 384
Query: 339 SDSSTASTPVAEQ---IERALDEVTSS-QPP----------PLPPPPPPAQETQEPSPIL 384
S P+ Q E AL+E + +PP PL P P +E +E
Sbjct: 385 RSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLST 444
Query: 385 DSEETRAAAPQAWAGPMEEPPQAQ-----------APPRGPGSPAE---DLMFMESAEQA 430
E AP + P+ + A+ P +PAE L SAE+A
Sbjct: 445 AMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEA 504
Query: 431 VLAAPVEPATADATEIHDAADTIE---TDTATADTTVANNVPP------AATSLIDLWPG 481
A V+ A+ T +A+ I+ A AD T A P A + ++
Sbjct: 505 --HAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSP 562
Query: 482 NGEGASTLQGEPRAPTPPSGTEVTLAEVPLLDEVAPEPLLPAGEGCATLLN--FDELP-- 537
+ +G S ++ P PPSG E T E ++ A E A + +E P
Sbjct: 563 SAKGVS-IEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAE 621
Query: 538 -EPPATFCDPEEVEGEPLAAPQTPTLPSALEELEQEQEPEPHLLTNGETTQKEGTQASEG 596
+PP P EV+ P P EE E +P P E Q + +
Sbjct: 622 VQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE-VQPPPAEEAPA 680
Query: 597 YFSQSQEEEFAQSEELCAKAPPPVFYNKPPEIDITCWDADPVPEEE 642
EE E L A PP AD VP EE
Sbjct: 681 EVQSLPAEETPIEETLAAVHSPP---------------ADDVPAEE 711
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 64.3 bits (155), Expect = 3e-10
Identities = 58/234 (24%), Positives = 103/234 (44%), Gaps = 21/234 (8%)
Query: 134 SNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKE 193
+ L+ LS RL+ +E+ E ++ + E REQ ++ E LRK+
Sbjct: 325 NQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQ 384
Query: 194 EERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKE 253
E+R + +ERLR E+ER++++ + ++E R ++E+++++ + + + ++L E
Sbjct: 385 EQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAE 444
Query: 254 -QSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPR-EFFKQQERVASASAGSCDVP 311
Q F D +E KKS ++E+ + ++ D E QQ + +P
Sbjct: 445 PQCSFEDLNNE------KKSALQLEQQVKELQEKLDEEHLEAASQQNQQLETQLSLVALP 498
Query: 312 SPFNHRPGSHLDSHRRMAPTPIP-----------TRSPSDSSTASTPVAEQIER 354
+ G HLDS AP P P T S D EQ+ER
Sbjct: 499 GEGD--GGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQVER 550
Score = 43.1 bits (100), Expect = 8e-04
Identities = 36/137 (26%), Positives = 74/137 (54%), Gaps = 16/137 (11%)
Query: 178 EQFWEQAKK--------EEELRKEEERKKALDERLRFEQERM-EQERQEQEERERRYRER 228
EQ ++AK E +L+ + E +AL + +++R+ EQE +E+ +R RE+
Sbjct: 298 EQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQ 357
Query: 229 EQQIEEHRR---KQQTLEAEEAKRRLKEQSI-FGDHRDEEEETHMKKSESEVEEAAAIIA 284
E+ E++ R +Q+TL+ + + R +EQ + + R +EE ++K E + + +
Sbjct: 358 ERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLW 417
Query: 285 QRPDNPREFFKQQERVA 301
++ + + KQ+ER+A
Sbjct: 418 KKEERLQ---KQEERLA 431
Score = 32.3 bits (72), Expect = 1.4
Identities = 41/189 (21%), Positives = 73/189 (38%), Gaps = 55/189 (29%)
Query: 191 RKEEERKKALDERLRFEQERMEQERQ-------EQEERERRYREREQQIEEHRRKQQTLE 243
R EE K L RL++ +R+++ + +Q+E +R RE + HRR QQT+
Sbjct: 149 RHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVL--HRRLQQTI- 205
Query: 244 AEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASA 303
KE+++ H + E+ +K+ + E +E A
Sbjct: 206 --------KERALLNAHVTQVTES-LKQVQLERDEYA----------------------- 233
Query: 304 SAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVTS-- 361
H G RM + R+ + +++ER+L E+ +
Sbjct: 234 -----------KHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQM 282
Query: 362 SQPPPLPPP 370
++PP L PP
Sbjct: 283 AKPPSLAPP 291
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 63.9 bits (154), Expect = 4e-10
Identities = 57/234 (24%), Positives = 103/234 (44%), Gaps = 21/234 (8%)
Query: 134 SNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKE 193
+ L+ LS RL+ +E+ E ++ + E REQ ++ E LRK+
Sbjct: 325 NQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQ 384
Query: 194 EERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKE 253
E+R + +ERLR E+ER++++ + ++E R ++E+++++ + + + ++L E
Sbjct: 385 EQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAE 444
Query: 254 -QSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPR-EFFKQQERVASASAGSCDVP 311
Q F D +E KKS ++E+ + ++ D E Q+ + +P
Sbjct: 445 PQCSFEDLNNE------KKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQLSLVALP 498
Query: 312 SPFNHRPGSHLDSHRRMAPTPIP-----------TRSPSDSSTASTPVAEQIER 354
+ G HLDS AP P P T S D EQ+ER
Sbjct: 499 GEGD--GGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQVER 550
Score = 44.3 bits (103), Expect = 4e-04
Identities = 37/156 (23%), Positives = 82/156 (52%), Gaps = 9/156 (5%)
Query: 152 EDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKK-EEELRKEEERKKALDERLRFEQER 210
+++ AEP + VE + + ++ + E +L+ + E +AL + +++R
Sbjct: 279 KNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQR 338
Query: 211 M-EQERQEQEERERRYREREQQIEEHRR---KQQTLEAEEAKRRLKEQSI-FGDHRDEEE 265
+ EQE +E+ +R RE+E+ E++ R +Q+TL+ + + R +EQ + + R +E
Sbjct: 339 LQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKE 398
Query: 266 ETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVA 301
E ++K E + + + ++ + + KQ+ER+A
Sbjct: 399 EERLQKQEKRLWDQEERLWKKEERLQ---KQEERLA 431
Score = 32.0 bits (71), Expect = 1.8
Identities = 46/235 (19%), Positives = 88/235 (37%), Gaps = 31/235 (13%)
Query: 158 PVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKE-----EERKKALDERLRFEQERME 212
P + YQ+ A+E + Q E + ++ +K+ EE KK +E + + E++E
Sbjct: 66 PGDSQYQELAVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQLE 125
Query: 213 Q------ERQEQE------ERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDH 260
E+ + + +R R+ E E + R + +E +R L S
Sbjct: 126 TINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQHIQELERALCAVSTQQQE 185
Query: 261 RDEEE---ETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHR 317
D E +++ + + A++ E KQ + A H
Sbjct: 186 EDRSSSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYA---------KHI 236
Query: 318 PGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVTS--SQPPPLPPP 370
G RM + R+ + +++ER+L E+ + ++PP L PP
Sbjct: 237 KGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPP 291
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 63.9 bits (154), Expect = 4e-10
Identities = 57/234 (24%), Positives = 103/234 (44%), Gaps = 21/234 (8%)
Query: 134 SNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKE 193
+ L+ LS RL+ +E+ E ++ + E REQ ++ E LRK+
Sbjct: 325 NQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQ 384
Query: 194 EERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKE 253
E+R + +ERLR E+ER++++ + ++E R ++E+++++ + + + ++L E
Sbjct: 385 EQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAE 444
Query: 254 -QSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPR-EFFKQQERVASASAGSCDVP 311
Q F D +E KKS ++E+ + ++ D E Q+ + +P
Sbjct: 445 PQCSFEDLNNE------KKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQLSLVALP 498
Query: 312 SPFNHRPGSHLDSHRRMAPTPIP-----------TRSPSDSSTASTPVAEQIER 354
+ G HLDS AP P P T S D EQ+ER
Sbjct: 499 GEGD--GGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQVER 550
Score = 44.3 bits (103), Expect = 4e-04
Identities = 37/156 (23%), Positives = 82/156 (52%), Gaps = 9/156 (5%)
Query: 152 EDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKK-EEELRKEEERKKALDERLRFEQER 210
+++ AEP + VE + + ++ + E +L+ + E +AL + +++R
Sbjct: 279 KNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQR 338
Query: 211 M-EQERQEQEERERRYREREQQIEEHRR---KQQTLEAEEAKRRLKEQSI-FGDHRDEEE 265
+ EQE +E+ +R RE+E+ E++ R +Q+TL+ + + R +EQ + + R +E
Sbjct: 339 LQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKE 398
Query: 266 ETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVA 301
E ++K E + + + ++ + + KQ+ER+A
Sbjct: 399 EERLQKQEKRLWDQEERLWKKEERLQ---KQEERLA 431
Score = 33.1 bits (74), Expect = 0.82
Identities = 46/235 (19%), Positives = 88/235 (37%), Gaps = 31/235 (13%)
Query: 158 PVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKE-----EERKKALDERLRFEQERME 212
P + YQ+ A+E + Q E + ++ +K+ EE KK +E + + E++E
Sbjct: 66 PGDSQYQELAVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQLE 125
Query: 213 Q------ERQEQE------ERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDH 260
E+ + + +R R+ E E + R + +E +R L S
Sbjct: 126 TINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALSAVSTQQQE 185
Query: 261 RDEEE---ETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHR 317
D E +++ + + A++ E KQ + A H
Sbjct: 186 EDRSSSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYA---------KHI 236
Query: 318 PGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVTS--SQPPPLPPP 370
G RM + R+ + +++ER+L E+ + ++PP L PP
Sbjct: 237 KGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPP 291
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 63.9 bits (154), Expect = 4e-10
Identities = 46/156 (29%), Positives = 80/156 (51%), Gaps = 14/156 (8%)
Query: 148 LRLREDENAEPVGTTYQKTDAAVEMKRINR-------EQFWEQAKKEEELRKE-EERKKA 199
L+L E+E E Q+ E +R R E+ ++ + E++LR+E EER++
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ 548
Query: 200 L---DERLRFEQERMEQE-RQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQS 255
L +E R EQER EQ ++EQEER + +RE++ + R K++ + E ++RLK +
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE--QEERLEQRLKREE 606
Query: 256 IFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPR 291
+ ++E E +K+ E E E ++ R
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
Score = 62.0 bits (149), Expect = 2e-09
Identities = 46/155 (29%), Positives = 83/155 (53%), Gaps = 12/155 (7%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQA---KKEEELRKEEERKKALDERLR 205
R +++E E Q+ + + R +E+ EQ ++EEE R+++ R++ +ER
Sbjct: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE 374
Query: 206 FEQERMEQERQEQEERERRYREREQQI--EEHRRKQQTLEAEEAKRRLKEQSIFGDHRDE 263
+ R +Q R+EQ+ R + REQQ+ E+ R++Q L E+ RR EQ + R++
Sbjct: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR--EQQL---RREQ 429
Query: 264 EEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQE 298
EEE H +K E E E + + + R++ K++E
Sbjct: 430 EEERHEQKHEQERREQR--LKREQEERRDWLKREE 462
Score = 61.6 bits (148), Expect = 2e-09
Identities = 31/111 (27%), Positives = 69/111 (62%), Gaps = 5/111 (4%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQE-RQEQEER--ERRYRE 227
++ + E+ EQ ++E+ L++E+E ++ D+ L+ E+ER +Q ++EQEER +R RE
Sbjct: 548 QLLKREEEKRLEQERREQRLKREQEERR--DQLLKREEERRQQRLKREQEERLEQRLKRE 605
Query: 228 REQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEE 278
+++E+ R++Q L+ EE + ++Q + + ++E + +++ + E E
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656
Score = 61.2 bits (147), Expect = 3e-09
Identities = 47/149 (31%), Positives = 73/149 (48%), Gaps = 24/149 (16%)
Query: 171 EMKRINREQFWEQAKKEEE------LRKEEER-----KKALDERLRFEQERMEQERQEQE 219
E KR+ +E+ ++ K+E+E L++EEER K+ +ERL +R E ER EQE
Sbjct: 554 EEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQE 613
Query: 220 ER-------ERRYREREQQI----EEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETH 268
ER E ER QQ+ E+ R+QQ L E+ +RR EQ + + +E E
Sbjct: 614 ERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR--EQRLKREEEEERLEQR 671
Query: 269 MKKSESEVEEAAAIIAQRPDNPREFFKQQ 297
+K+ E + + + RE K +
Sbjct: 672 LKREHEEERREQELAEEEQEQARERIKSR 700
Score = 60.8 bits (146), Expect = 4e-09
Identities = 39/142 (27%), Positives = 76/142 (53%), Gaps = 12/142 (8%)
Query: 164 QKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERM----EQERQEQE 219
Q+TD ++ E+ Q ++E+ LR++E +K +E LR +++ E++R ++
Sbjct: 1332 QETD-----RKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQ 1386
Query: 220 ERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRD---EEEETHMKKSESEV 276
ERER++ + EQQ+ R+QQ + + K R +EQ + RD EEE +++ E E
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERER 1446
Query: 277 EEAAAIIAQRPDNPREFFKQQE 298
+ R + R+F ++++
Sbjct: 1447 KFLEEEQQLRQERHRKFREEEQ 1468
Score = 60.1 bits (144), Expect = 6e-09
Identities = 36/99 (36%), Positives = 60/99 (60%), Gaps = 9/99 (9%)
Query: 182 EQAKKEE--ELRKEEERKKALDERLRFEQE---RMEQERQEQEERERRYREREQQIEEHR 236
EQ +K E ELR+E + ++ +RLR EQ+ + E+ER+EQ+E R +ER +Q EE
Sbjct: 276 EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE-- 333
Query: 237 RKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESE 275
R++Q L E+ +RR EQ + + +E E +++ + E
Sbjct: 334 RREQQLRREQEERR--EQQLRREQEEERREQQLRREQEE 370
Score = 59.7 bits (143), Expect = 8e-09
Identities = 41/154 (26%), Positives = 76/154 (49%), Gaps = 7/154 (4%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQ 208
+ REDE Q + K + E + ++E++LR + +RK +E+L E
Sbjct: 1620 KFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG 1679
Query: 209 ERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETH 268
E + RQE R+R++RE EQQ+ R+++ L+ E+ RR + + F + +ET
Sbjct: 1680 EEQQLRRQE---RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736
Query: 269 MKKSESEVEEAAAIIAQ---RPDNPREFFKQQER 299
++ + E I+ + RP+ + ++QER
Sbjct: 1737 QEQLRRQ-ERYRKILEEEQLRPEREEQQLRRQER 1769
Score = 58.2 bits (139), Expect = 2e-08
Identities = 51/172 (29%), Positives = 90/172 (52%), Gaps = 21/172 (12%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEE----ERKKALDERL 204
R +E+E E Q+ +++R + + +Q ++E++LR+E+ E++ +++L
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 425
Query: 205 RFEQE------RMEQERQEQ----EERERR-YREREQQIEEH---RRKQQTLEAEEAKRR 250
R EQE + EQER+EQ E+ ERR + +RE++ E H RRKQQ +E +RR
Sbjct: 426 RREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERR 485
Query: 251 LKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVAS 302
+ + + R E++E ++ E EE QR E + Q+R+ S
Sbjct: 486 ERWLKLEEEERREQQERREQQLRREQEERR---EQRLKRQEEEERLQQRLRS 534
Score = 58.2 bits (139), Expect = 2e-08
Identities = 36/130 (27%), Positives = 74/130 (56%), Gaps = 9/130 (6%)
Query: 176 NREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQ--EERERRYREREQQIE 233
++EQ + ++E+ LR++E +K L E EQ+ QER++Q ++R+R++RE EQQ+
Sbjct: 1369 HQEQGRKFLEEEQRLRRQERERKFLKE----EQQLRCQEREQQLRQDRDRKFREEEQQLS 1424
Query: 234 EHRRKQQTLEAE-EAKRRLKEQSIFGDHRDEEEETHMKKSESE--VEEAAAIIAQRPDNP 290
R ++ E E + +R+ +E+ + + +E H K E E ++E R +
Sbjct: 1425 RQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERD 1484
Query: 291 REFFKQQERV 300
R+F ++++++
Sbjct: 1485 RKFLEEEQQL 1494
Score = 57.8 bits (138), Expect = 3e-08
Identities = 39/140 (27%), Positives = 76/140 (54%), Gaps = 19/140 (13%)
Query: 173 KRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQE--QEERERRYREREQ 230
++ E+ Q ++E+LR++E +K L+E EQ R E+E Q+ ++ER+R++RE EQ
Sbjct: 1723 RKFREEEQLRQETEQEQLRRQERYRKILEE----EQLRPEREEQQLRRQERDRKFREEEQ 1778
Query: 231 QIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEE--------ETHMKKSESEVEEAAAI 282
+E R++Q L ++E+ R+ +E+ R+E++ + ++ + ++EE
Sbjct: 1779 LRQE--REEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR 1836
Query: 283 IAQRPD---NPREFFKQQER 299
+ Q D E F QE+
Sbjct: 1837 LRQERDRQYRAEEQFATQEK 1856
Score = 57.8 bits (138), Expect = 3e-08
Identities = 38/122 (31%), Positives = 74/122 (60%), Gaps = 14/122 (11%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEE----RKKALDERLRFEQERMEQERQEQ---EERER 223
E +++ ++ + ++EE+LR+E E R + D + R+E+E+++ E QEQ +ER+R
Sbjct: 1784 EEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDR 1843
Query: 224 RYREREQ--QIEEHRRKQQTL--EAEEAKRRLKEQSIFGDH---RDEEEETHMKKSESEV 276
+YR EQ E+ RR++Q L E E+ +R+ +E+ + +H + +EE+ H + E +
Sbjct: 1844 QYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKS 1903
Query: 277 EE 278
+E
Sbjct: 1904 QE 1905
Score = 57.4 bits (137), Expect = 4e-08
Identities = 35/125 (28%), Positives = 64/125 (51%), Gaps = 10/125 (8%)
Query: 177 REQFWEQAKKEEELRKEEE--RKKALDERLRFEQERMEQERQEQEERERRYREREQQIEE 234
R+Q W +EE R+ K AL E+LR EQ+ +++E +E + ER R R++Q +
Sbjct: 870 RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ 929
Query: 235 HRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFF 294
+R ++Q + EE R + + R +E E +K + ++ ++ + P+ R
Sbjct: 930 YREEEQLQQEEEQLLREEREK----RRRQERERQYRKDKKLQQKEEQLLGEEPEKRR--- 982
Query: 295 KQQER 299
+QER
Sbjct: 983 -RQER 986
Score = 57.0 bits (136), Expect = 5e-08
Identities = 28/104 (26%), Positives = 61/104 (58%), Gaps = 3/104 (2%)
Query: 170 VEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYRERE 229
+E + + RE+ E+ +++ R+++ R+K +ER ++ER EQ+ + +++ ERR ++
Sbjct: 281 LERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLR 340
Query: 230 QQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSE 273
++ EE R +Q E EE +R EQ + + +E E +++ +
Sbjct: 341 REQEERREQQLRREQEEERR---EQQLRREQEEERREQQLRREQ 381
Score = 56.2 bits (134), Expect = 9e-08
Identities = 47/176 (26%), Positives = 87/176 (49%), Gaps = 12/176 (6%)
Query: 139 RLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKR--INREQFWEQAKKEEELRKEEER 196
RL RL+ +E E K++ E ++ + REQ Q ++E+ L++EEE
Sbjct: 609 RLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ---QERREQRLKREEEE 665
Query: 197 KKALDERLR--FEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQ 254
++ L++RL+ E+ER EQE E+E+ + R R + + + + + +A ++K + +
Sbjct: 666 ER-LEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724
Query: 255 SIFGDHRDEEEETHMKKSESEV----EEAAAIIAQRPDNPREFFKQQERVASASAG 306
G R +E+E ++ ESE+ EE A Q + R+F Q + + G
Sbjct: 725 KQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERG 780
Score = 56.2 bits (134), Expect = 9e-08
Identities = 38/139 (27%), Positives = 77/139 (55%), Gaps = 12/139 (8%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQE-----ERERRY 225
E K + EQ ++E++LR++ +RK +E+ QER + R+E++ ERER++
Sbjct: 1389 ERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKF 1448
Query: 226 REREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDE---EEETHMKKSESEVE-EAAA 281
E EQQ+ + R + + E E+ + +EQ + RD EEE +++ E + +
Sbjct: 1449 LEEEQQLRQERHR-KFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE 1507
Query: 282 IIAQRPDNPREFFKQQERV 300
+ +Q P+ R+F ++++++
Sbjct: 1508 LRSQEPE--RKFLEEEQQL 1524
Score = 55.8 bits (133), Expect = 1e-07
Identities = 38/128 (29%), Positives = 69/128 (53%), Gaps = 12/128 (9%)
Query: 182 EQAKKEEELRKEEE---RKKALDERLRFEQERMEQERQEQEERERRYRE-------REQQ 231
E+ EE+LR+ E R+K +E+ + +ER ++ QE+EE+E R RE + Q
Sbjct: 202 EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261
Query: 232 IEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPR 291
EE +R+++ E EE R+L+ Q + + ++EE++ + E ++ +R +
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQE--EERREQQE 319
Query: 292 EFFKQQER 299
E +QQER
Sbjct: 320 ERREQQER 327
Score = 55.8 bits (133), Expect = 1e-07
Identities = 43/154 (27%), Positives = 80/154 (51%), Gaps = 6/154 (3%)
Query: 151 REDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQER 210
++ + E +Q+ + KR + E+ +EEE +++ E ++ ++ + E++
Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQE 285
Query: 211 MEQERQEQEERERRYREREQQI----EEHRRKQQTLEAEEAKRR-LKEQSIFGDHRDEEE 265
+ +ERQE+E++++R R REQQ+ EE RR+QQ E+ +RR +E+ R E+E
Sbjct: 286 LRRERQEEEQQQQRLR-REQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE 344
Query: 266 ETHMKKSESEVEEAAAIIAQRPDNPREFFKQQER 299
E ++ E EE R + E +QQ R
Sbjct: 345 ERREQQLRREQEEERREQQLRREQEEERREQQLR 378
Score = 55.8 bits (133), Expect = 1e-07
Identities = 40/114 (35%), Positives = 67/114 (58%), Gaps = 11/114 (9%)
Query: 173 KRINREQFWEQAKKEEELRK--EEERKKALDERLRFEQERMEQ--ERQEQEERERRYRER 228
+R EQ ++ ++E++LR+ EEER++ +ER R +QER EQ ER+EQ+ R + R
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEER-REQQERREQQEERREQQLRREQEERR 347
Query: 229 EQQI----EEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEE 278
EQQ+ EE RR+QQ +E +RR EQ + + + E+ ++ + E+
Sbjct: 348 EQQLRREQEEERREQQLRREQEEERR--EQQLRREQQLRREQQLRREQQLRREQ 399
Score = 55.8 bits (133), Expect = 1e-07
Identities = 37/138 (26%), Positives = 76/138 (55%), Gaps = 22/138 (15%)
Query: 171 EMKRINREQFWEQAKK----EEELRKEEERK-KALDERLRFEQERMEQERQEQ---EERE 222
E R + W+Q + EE+L +EE+++ K D + + E++ + +ER+E+ +E +
Sbjct: 1276 ERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETD 1335
Query: 223 RRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAI 282
R++RE EQ ++E R++Q L +E R+ + EEE H ++ +EE +
Sbjct: 1336 RKFREEEQLLQE--REEQPLRRQERDRKFR----------EEELRHQEQGRKFLEEEQRL 1383
Query: 283 IAQRPDNPREFFKQQERV 300
+R + R+F K+++++
Sbjct: 1384 --RRQERERKFLKEEQQL 1399
Score = 55.8 bits (133), Expect = 1e-07
Identities = 37/136 (27%), Positives = 69/136 (50%), Gaps = 18/136 (13%)
Query: 177 REQFWEQAKKEEELRKEEERKKALDER------------LRFEQERMEQER--QEQEERE 222
R Q ++ +E+ELR +E +K L+E L+ EQ+ QER Q +++R+
Sbjct: 1495 RRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD 1554
Query: 223 RRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAI 282
R++RE EQ +E +Q + + + K RL+EQ + R +E+E + E ++
Sbjct: 1555 RKFREEEQLRQEREEQQLSRQERDRKFRLEEQKV----RRQEQERKFMEDEQQLRRQEGQ 1610
Query: 283 IAQRPDNPREFFKQQE 298
R + R+F + ++
Sbjct: 1611 QQLRQERDRKFREDEQ 1626
Score = 55.8 bits (133), Expect = 1e-07
Identities = 39/144 (27%), Positives = 82/144 (56%), Gaps = 16/144 (11%)
Query: 171 EMKRINREQFWEQ-AKKEEELRKEE---ERKKALDERLRFEQERMEQERQEQ----EERE 222
E ++++R+Q + ++E++LR++E +R++ D + R E+E++ QER+EQ +ER+
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR-EEEQLRQEREEQQLSRQERD 1578
Query: 223 RRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRD----EEEETHMKKSESEV-- 276
R++R EQ++ ++++ +E E+ RR + Q RD E+E+ ++ E ++
Sbjct: 1579 RKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHR 1638
Query: 277 -EEAAAIIAQRPDNPREFFKQQER 299
E + + P R+ +QQ R
Sbjct: 1639 QERDRKFLEEEPQLRRQEREQQLR 1662
Score = 55.5 bits (132), Expect = 2e-07
Identities = 38/133 (28%), Positives = 67/133 (50%), Gaps = 25/133 (18%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEERK----KALDERLRFEQERMEQERQEQEERERRYR 226
E + EQ EQ ++E+ L++E+E + K +E R EQER +Q+ + +E ERR R
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 227 --------------EREQQI--EEHRRKQQTLEAEEAKRRLK-----EQSIFGDHRDEEE 265
REQQ+ E+ R++Q L+ +E + RL+ EQ + + + E
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547
Query: 266 ETHMKKSESEVEE 278
+ ++ E +E+
Sbjct: 548 QLLKREEEKRLEQ 560
Score = 55.5 bits (132), Expect = 2e-07
Identities = 33/132 (25%), Positives = 71/132 (53%), Gaps = 4/132 (3%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQE--RQEQEERERRYR-- 226
E +R +E+ +Q K+++E + E K +E R +QER EQ+ R+++E RE+R +
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQ 522
Query: 227 EREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQR 286
E E+++++ R +Q L E+ +RR + + R E+E + + E ++ +
Sbjct: 523 EEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKRE 582
Query: 287 PDNPREFFKQQE 298
+ ++ K+++
Sbjct: 583 EERRQQRLKREQ 594
Score = 55.1 bits (131), Expect = 2e-07
Identities = 50/175 (28%), Positives = 83/175 (47%), Gaps = 26/175 (14%)
Query: 143 PVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWE-QAKKEEELRKEEER----- 196
P R + RE + E ++ E + R Q WE Q +K++EL++EEE+
Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
Query: 197 --KKALDERLRFEQERMEQERQEQEER---ERRYREREQQIEEHRRKQ--------QTLE 243
K+ L ER R Q R E+E Q++EE+ E R R Q++E RK+ Q L
Sbjct: 1038 REKRRLQERER--QYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLR 1095
Query: 244 AEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQE 298
E KRR +E+ R EE +++ E ++ +R + R++ +++E
Sbjct: 1096 EEPEKRRRQER-----ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEE 1145
Score = 55.1 bits (131), Expect = 2e-07
Identities = 34/112 (30%), Positives = 66/112 (58%), Gaps = 7/112 (6%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEER--KKALDERLRFEQERMEQERQEQEERERRYRER 228
E ++ R++ Q ++EEE+++EEE+ ++ ++R R E ER +E +E ++ E +
Sbjct: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE 1186
Query: 229 EQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMK-KSESEVEEA 279
EQ+ R++Q E EE +R+ ++Q +RDE++ + +K + E E E A
Sbjct: 1187 EQEKRRQERERQYREEEELQRQKRKQR----YRDEDQRSDLKWQWEPEKENA 1234
Score = 54.7 bits (130), Expect = 3e-07
Identities = 40/156 (25%), Positives = 86/156 (55%), Gaps = 21/156 (13%)
Query: 152 EDENAEPVGTTYQKTDAAVEMKRINR-----EQFWEQAKKEEELRKEEERKKALDERLRF 206
E+E T Y K ++++ + E+ ++ ++E+ R+E+ER+ +E+L+
Sbjct: 879 EEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQ 938
Query: 207 EQE---RMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDE 263
E+E R E+E++ ++ERER+YR +++++++ +++Q L E KRR R E
Sbjct: 939 EEEQLLREEREKRRRQERERQYR-KDKKLQQ--KEEQLLGEEPEKRR----------RQE 985
Query: 264 EEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQER 299
E+ + ++ E + EE + +R R+ +++Q R
Sbjct: 986 REKKYREEEELQQEEEQLLREEREKRRRQEWERQYR 1021
Score = 54.3 bits (129), Expect = 3e-07
Identities = 42/147 (28%), Positives = 71/147 (48%), Gaps = 18/147 (12%)
Query: 131 QRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEEL 190
+R L R +L RE+E + Q+ +KR E+ ++ ++E+ L
Sbjct: 561 ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620
Query: 191 RKEEERKKALDERLRFEQERMEQ--ERQEQEERERRYREREQQIEEHRRKQQTLEAEEAK 248
++EE E+ER +Q + +EQEER ++ REQQ R++Q L+ EE +
Sbjct: 621 KREEP-----------EEERRQQLLKSEEQEERRQQQLRREQQ----ERREQRLKREEEE 665
Query: 249 RRLKEQSIFGDHRDEEEETHMKKSESE 275
RL EQ + +H +E E + + E E
Sbjct: 666 ERL-EQRLKREHEEERREQELAEEEQE 691
Score = 54.3 bits (129), Expect = 3e-07
Identities = 51/173 (29%), Positives = 85/173 (49%), Gaps = 31/173 (17%)
Query: 147 RLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWE-QAKKEEELRKEEE---------R 196
RL+ RE + E ++ E + R Q E Q +KEEEL++EEE R
Sbjct: 1042 RLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKR 1101
Query: 197 KKALDERLRFEQERMEQE-----RQEQEERERRYREREQQIEE--HRRKQQTLEAEEAKR 249
++ ER E+E ++QE R+E+E+R R+ ER+ + EE + ++Q L E KR
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161
Query: 250 RLKEQSIFGDHRDEE----EETHMKKSESEVEEAAAIIAQRPDNPREFFKQQE 298
R Q + +R+EE EE + + E E +R + R++ +++E
Sbjct: 1162 R--RQELERQYREEEELQQEEEQLLREEQE--------KRRQERERQYREEEE 1204
Score = 53.9 bits (128), Expect = 4e-07
Identities = 37/136 (27%), Positives = 68/136 (50%), Gaps = 13/136 (9%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQ 230
E +R R+ Q K+E+ L +E E+++ + ++ +E Q+ +EQ RE R + R Q
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ 1014
Query: 231 QIEEHRRKQQTLEAEEA--------KRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAI 282
+ E RK+ L+ EE KRRL+E+ R EE +++ E ++
Sbjct: 1015 EWERQYRKKDELQQEEEQLLREEREKRRLQER-----ERQYREEEELQQEEEQLLGEERE 1069
Query: 283 IAQRPDNPREFFKQQE 298
+R + R++ K++E
Sbjct: 1070 TRRRQELERQYRKEEE 1085
Score = 53.5 bits (127), Expect = 6e-07
Identities = 43/169 (25%), Positives = 87/169 (51%), Gaps = 15/169 (8%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERL---R 205
RLR E Q+ +++ +++ + ++E++L ++E +K +E R
Sbjct: 1382 RLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRR 1441
Query: 206 FEQER--MEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRL--KEQSIFGDHR 261
E+ER +E+E+Q ++ER R++RE EQ ++E R++Q L +E R+ +EQ + R
Sbjct: 1442 QERERKFLEEEQQLRQERHRKFREEEQLLQE--REEQQLHRQERDRKFLEEEQQLRRQER 1499
Query: 262 DEE-EETHMKKSESE---VEEAAAIIAQRPDNPREFFKQQERVASASAG 306
D + E ++ E E +EE + R R+F ++++++ G
Sbjct: 1500 DRKFREQELRSQEPERKFLEEEQQL--HRQQRQRKFLQEEQQLRRQERG 1546
Score = 52.8 bits (125), Expect = 1e-06
Identities = 38/137 (27%), Positives = 70/137 (51%), Gaps = 17/137 (12%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQF----WEQAKKEEELRKEEERKKAL---- 200
R +E+E E QK + +R+ REQ W + ++E E ++E RK+ L
Sbjct: 427 REQEEERHE------QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 201 --DERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFG 258
+ R R+ + E+ R++QE RE++ R +++ E R K+Q E E ++RL+ +
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQE-EEERLQQRLRSEQQLR 539
Query: 259 DHRDEEEETHMKKSESE 275
++E E +K+ E +
Sbjct: 540 REQEERREQLLKREEEK 556
Score = 52.8 bits (125), Expect = 1e-06
Identities = 43/146 (29%), Positives = 76/146 (52%), Gaps = 33/146 (22%)
Query: 171 EMKRINREQFWEQAKKEEEL----------RKEEERKKALDERLRFEQERM---EQERQE 217
E +R RE+ EQ ++EEE R+E ER+ D++L+ ++E++ E E++
Sbjct: 925 EQERQYREE--EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRR 982
Query: 218 QEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVE 277
++ERE++YRE E+ +E ++Q L E KRR R E E + KK E + E
Sbjct: 983 RQEREKKYREEEELQQE---EEQLLREEREKRR----------RQEWERQYRKKDELQQE 1029
Query: 278 EAAAIIAQR-----PDNPREFFKQQE 298
E + +R + R++ +++E
Sbjct: 1030 EEQLLREEREKRRLQERERQYREEEE 1055
Score = 52.8 bits (125), Expect = 1e-06
Identities = 37/124 (29%), Positives = 68/124 (54%), Gaps = 19/124 (15%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEE----------RKKALDERLRFEQERMEQE----RQ 216
E ++ R++ Q ++EEEL++EEE R++ L+ + R E+E ++E R+
Sbjct: 1097 EPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLRE 1156
Query: 217 EQEERERRYREREQQIEE--HRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSES 274
E E+R R+ ER+ + EE + ++Q L E+ KRR + + +R+EEE K+ +
Sbjct: 1157 EPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERER---QYREEEELQRQKRKQR 1213
Query: 275 EVEE 278
+E
Sbjct: 1214 YRDE 1217
Score = 52.4 bits (124), Expect = 1e-06
Identities = 51/147 (34%), Positives = 83/147 (56%), Gaps = 24/147 (16%)
Query: 171 EMKRINREQFWEQ-AKKEEELRKEEERKKALDERLRFEQE-RMEQ--ERQEQEER-ERRY 225
++KR E+ E+ K EEE R+E++ ++ +++LR EQE R EQ +RQE+EER ++R
Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERR--EQQLRREQEERREQRLKRQEEEERLQQRL 532
Query: 226 REREQ-QIEEHRRKQQTLEAEEAKR--------RLKEQSIFGDHRDE----EEETHMKKS 272
R +Q + E+ R++Q L+ EE KR RLK + + RD+ EEE ++
Sbjct: 533 RSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQ--EERRDQLLKREEERRQQRL 590
Query: 273 ESEVEEAAAIIAQRPDNPREFFKQQER 299
+ E EE +R + R +Q+ER
Sbjct: 591 KREQEERLEQRLKREEVER--LEQEER 615
Score = 52.4 bits (124), Expect = 1e-06
Identities = 32/128 (25%), Positives = 67/128 (52%), Gaps = 8/128 (6%)
Query: 177 REQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHR 236
R Q ++ +EEE ++E ++ L + R + R+E+++ ++E+ER++ E EQQ+
Sbjct: 1549 RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE 1608
Query: 237 RKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQ------RPDNP 290
+QQ + + K R EQ + R+E++ ++ +EE + Q R D
Sbjct: 1609 GQQQLRQERDRKFREDEQLL--QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRD 1666
Query: 291 REFFKQQE 298
R+F ++++
Sbjct: 1667 RKFREEEQ 1674
Score = 52.0 bits (123), Expect = 2e-06
Identities = 37/138 (26%), Positives = 78/138 (56%), Gaps = 17/138 (12%)
Query: 173 KRINREQFWEQAKKEEELRKEEERKK--------ALDERLRFEQERMEQ--ERQEQEERE 222
+++ REQ Q ++E++LR+E+E ++ ++RL+ EQE +R+E+ ER
Sbjct: 411 QQLRREQ---QLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467
Query: 223 RRYREREQ--QIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAA 280
+ R ++Q + +E R+++ L+ EE +RR +++ R E+EE ++ + + EE
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER 527
Query: 281 AIIAQRPDNPREFFKQQE 298
+ QR + ++ ++QE
Sbjct: 528 --LQQRLRSEQQLRREQE 543
Score = 51.2 bits (121), Expect = 3e-06
Identities = 31/126 (24%), Positives = 68/126 (53%), Gaps = 7/126 (5%)
Query: 178 EQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQ---EERERRYREREQQIEE 234
EQ ++ ++++ R+E +RK +E+ QER + R+++ +E ER++ E EQQ+
Sbjct: 1467 EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR 1526
Query: 235 HRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFF 294
+R+++ L+ E+ RR + G R ++ + ++ E +E R + R+F
Sbjct: 1527 QQRQRKFLQEEQQLRRQER----GQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR 1582
Query: 295 KQQERV 300
++++V
Sbjct: 1583 LEEQKV 1588
Score = 51.2 bits (121), Expect = 3e-06
Identities = 38/114 (33%), Positives = 64/114 (56%), Gaps = 10/114 (8%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQE-----RMEQERQ-EQEERERR 224
E K + EQ + + +++LR+E +RK DE+L E+E R E++R+ +EE + R
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653
Query: 225 YREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRD---EEEETHMKKSESE 275
+EREQQ+ H R ++ E E+ + +EQ + RD EEE +++ E E
Sbjct: 1654 RQEREQQL-RHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERE 1706
Score = 51.2 bits (121), Expect = 3e-06
Identities = 35/116 (30%), Positives = 64/116 (55%), Gaps = 12/116 (10%)
Query: 171 EMKRINREQFWEQAKKEEELRKEE-ERKKALDERLRFEQERMEQERQEQ-----EERERR 224
+++R RE+ + Q +E++LR++E ERK +E+LR E E+ + RQE+ EE + R
Sbjct: 1699 QLRRQERERKFLQ--EEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLR 1756
Query: 225 YREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRD----EEEETHMKKSESEV 276
EQQ+ R ++ E E+ ++ +EQ + D EEE+ ++ E ++
Sbjct: 1757 PEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQL 1812
Score = 50.8 bits (120), Expect = 4e-06
Identities = 35/143 (24%), Positives = 76/143 (53%), Gaps = 11/143 (7%)
Query: 164 QKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERER 223
Q+ + E++ + E+ ++ ++ ++L++EE+ + ER R +++R +Q+ + Q E ER
Sbjct: 823 QRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEER 882
Query: 224 RYRER----EQQIEEHRRKQQTL---EAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEV 276
+ R + ++E RK+Q L E EE +R +E+ R E+E + ++ + +
Sbjct: 883 KRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKR----RRQEQERQYREEEQLQQ 938
Query: 277 EEAAAIIAQRPDNPREFFKQQER 299
EE + +R R+ ++Q R
Sbjct: 939 EEEQLLREEREKRRRQERERQYR 961
Score = 50.8 bits (120), Expect = 4e-06
Identities = 38/131 (29%), Positives = 74/131 (56%), Gaps = 12/131 (9%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQ 230
E KR +R+ E+ EE R+E+ R++ D + R E+E++ QER+EQ R R+ R+R+
Sbjct: 1306 EAKRRDRKSQEEKQLLREE-REEKRRRQETDRKFR-EEEQLLQEREEQPLR-RQERDRKF 1362
Query: 231 QIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNP 290
+ EE R ++Q + E ++RL+ Q EE++ ++ E ++ R D
Sbjct: 1363 REEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQL---------RQDRD 1413
Query: 291 REFFKQQERVA 301
R+F +++++++
Sbjct: 1414 RKFREEEQQLS 1424
Score = 50.8 bits (120), Expect = 4e-06
Identities = 37/139 (26%), Positives = 74/139 (53%), Gaps = 18/139 (12%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEERKKAL----DERLRFEQERME-QERQEQEERERRY 225
E +R+ R++ + KEE+ + +ER++ L D + R E++++ Q ER+R++
Sbjct: 1379 EEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQ------ERDRKF 1432
Query: 226 REREQQIEEHRRKQQTLEAE-----EAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAA 280
RE EQQ+ R+++ LE E E R+ +E+ R+E++ ++ +EE
Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQ 1492
Query: 281 AIIAQRPDNPREFFKQQER 299
+ +R + R+F +Q+ R
Sbjct: 1493 QL--RRQERDRKFREQELR 1509
Score = 50.8 bits (120), Expect = 4e-06
Identities = 33/124 (26%), Positives = 70/124 (56%), Gaps = 16/124 (12%)
Query: 185 KKEEELRKEEERKKALDERLRF---EQERMEQERQ-EQEERERRYREREQQIEEHRRKQQ 240
++E++LR++E +K ++ LR E++ +E+E+Q +++R+R++ + EQQ+ R QQ
Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ 1548
Query: 241 TLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESE----VEEAAAIIAQRPDNPREFFKQ 296
+ + K R +EQ R E EE + + E + +EE +R + R+F +
Sbjct: 1549 RRQDRDRKFREEEQL-----RQEREEQQLSRQERDRKFRLEEQK---VRRQEQERKFMED 1600
Query: 297 QERV 300
++++
Sbjct: 1601 EQQL 1604
Score = 50.4 bits (119), Expect = 5e-06
Identities = 36/150 (24%), Positives = 80/150 (53%), Gaps = 22/150 (14%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEERKKALD--------ERLRFEQERMEQERQE--QEE 220
E++R RE+ Q ++E+ LR+E E+++ + E L+ E+E++ +E QE ++E
Sbjct: 1135 ELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE 1194
Query: 221 RERRYREREQQIEEHRRKQQTLEAE-----------EAKRRLKEQSIFGDHRDEEEETHM 269
RER+YRE E++++ +RKQ+ + + E + +++ ++ R+ E+ +
Sbjct: 1195 RERQYRE-EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQL 1253
Query: 270 KKSESEVEEAAAIIAQRPDNPREFFKQQER 299
+ S+ ++ + +E ++QER
Sbjct: 1254 EDSQLRDRQSQQDLQHLLGEQQERDREQER 1283
Score = 50.4 bits (119), Expect = 5e-06
Identities = 29/110 (26%), Positives = 60/110 (54%), Gaps = 8/110 (7%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQ 230
+++R R++ + + +E++LR++E +K L E + R E ER+ +EE + R ++
Sbjct: 1683 QLRRQERDRKFRE--EEQQLRRQERERKFLQEEQQLR--RQELERKFREEEQLRQETEQE 1738
Query: 231 QIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRD----EEEETHMKKSESEV 276
Q+ R ++ LE E+ + +EQ + RD EEE+ ++ E ++
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQL 1788
Score = 50.4 bits (119), Expect = 5e-06
Identities = 34/130 (26%), Positives = 73/130 (56%), Gaps = 4/130 (3%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQ 230
E +++ R++ + ++EE+LR+E E ++ + + EQ RQE+EE++ R ++R+
Sbjct: 1760 EEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRD- 1818
Query: 231 QIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNP 290
++R +++ L+ EE ++RL+++ +R EE+ +KS E +E Q+
Sbjct: 1819 --GKYRWEEEQLQLEEQEQRLRQER-DRQYRAEEQFATQEKSRREEQELWQEEEQKRRQE 1875
Query: 291 REFFKQQERV 300
RE ++E +
Sbjct: 1876 RERKLREEHI 1885
Score = 50.1 bits (118), Expect = 6e-06
Identities = 40/153 (26%), Positives = 73/153 (47%), Gaps = 40/153 (26%)
Query: 182 EQAKKEEELRKEEERKKALDERLRFEQERMEQ------------ERQEQEERERRYRERE 229
E ++ + R+E+ER+ A E +QER+EQ +RQE +ERE R E E
Sbjct: 132 EPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEE 191
Query: 230 Q------------QIEEHRRKQQTL-------EAEEAKRRLKEQSIFGDHRDEE---EET 267
Q EE R+++ L E ++ +RR ++ +F + ++E ET
Sbjct: 192 QLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRET 251
Query: 268 HMKKSESEVEEAAAIIAQRPDNPREFFKQQERV 300
++K E +++E + P RE +++E++
Sbjct: 252 VLRKEEEKLQE------EEPQRQRELQEEEEQL 278
Score = 49.7 bits (117), Expect = 8e-06
Identities = 39/144 (27%), Positives = 77/144 (53%), Gaps = 27/144 (18%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEER--KKALDERLRFEQER-------MEQERQE--QE 219
E ++ R++ ++ ++EEEL++EEE+ ++ ++R R E ER ++QE ++ +E
Sbjct: 977 EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036
Query: 220 ERE-RRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRD----EEEETHMKKSES 274
ERE RR +ERE+Q E QQ +E+ + G+ R+ +E E +K E
Sbjct: 1037 EREKRRLQERERQYREEEELQQ-----------EEEQLLGEERETRRRQELERQYRKEEE 1085
Query: 275 EVEEAAAIIAQRPDNPREFFKQQE 298
+E ++ + P+ R ++++
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERERQ 1109
Score = 49.7 bits (117), Expect = 8e-06
Identities = 36/132 (27%), Positives = 64/132 (48%), Gaps = 10/132 (7%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQ 208
+ RE+E G Q + K EQ + ++E + +EE++ + + +F +
Sbjct: 1668 KFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFRE 1727
Query: 209 ERMEQERQEQEERERRYREREQQIEEH-----RRKQQTLEAEEAKRRLKEQSIFGDHRDE 263
E EQ RQE E+ + R +ER ++I E R++Q L +E R+ +E+ R E
Sbjct: 1728 E--EQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEE---QLRQE 1782
Query: 264 EEETHMKKSESE 275
EE ++ ES+
Sbjct: 1783 REEQQLRSQESD 1794
Score = 48.9 bits (115), Expect = 1e-05
Identities = 37/148 (25%), Positives = 80/148 (54%), Gaps = 24/148 (16%)
Query: 171 EMKRINREQFWEQAKKEEE-LRKEEERKKALDERLRFEQERMEQERQE----QE------ 219
E ++++R++ + ++EE+ +R++E +K L+E + QER + R+E QE
Sbjct: 1419 EEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQL 1478
Query: 220 ---ERERRYREREQQIEEHRR----KQQTLEAEEAKRRL--KEQSIFGDHRDEEEETHMK 270
ER+R++ E EQQ+ R ++Q L ++E +R+ +EQ + HR + + ++
Sbjct: 1479 HRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL---HRQQRQRKFLQ 1535
Query: 271 KSESEVEEAAAIIAQRPDNPREFFKQQE 298
+ E ++ +R D R+F ++++
Sbjct: 1536 E-EQQLRRQERGQQRRQDRDRKFREEEQ 1562
Score = 48.1 bits (113), Expect = 2e-05
Identities = 39/163 (23%), Positives = 84/163 (51%), Gaps = 19/163 (11%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKK----EEELRKEEERKKALDERL 204
+LR++ + + + +E +++ R+ EQ +K E++LR++E +++ ER
Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQ---EQERKFMEDEQQLRRQEGQQQLRQERD 1618
Query: 205 RFEQERMEQERQEQE-------ERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIF 257
R +E EQ QE+E ER+R++ E E Q+ R+QQ + K R +EQ +
Sbjct: 1619 RKFRED-EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLL- 1676
Query: 258 GDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERV 300
EE++ ++ + + E + +R + R+F ++++++
Sbjct: 1677 --QEGEEQQLRRQERDRKFREEEQQL-RRQERERKFLQEEQQL 1716
Score = 47.8 bits (112), Expect = 3e-05
Identities = 38/179 (21%), Positives = 85/179 (47%), Gaps = 13/179 (7%)
Query: 131 QRLSNGLARLSSPVLHRLRLREDENA---EPVGTTYQKTDAAVEMKRINRE-QFWEQAKK 186
+RL L R L E+E E + + K +E + R+ + + + +K
Sbjct: 666 ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRK 725
Query: 187 EEELRK---EEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLE 243
+E R+ +EE+++ + L++++E +Q++EE+ R + + Q E+ R +Q L
Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS 785
Query: 244 AEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPRE--FFKQQERV 300
A R +E+ + + R + E+ + + E + + QR + +E F +++E++
Sbjct: 786 ARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRR----RQRREREKELQFLEEEEQL 840
Score = 47.0 bits (110), Expect = 5e-05
Identities = 36/129 (27%), Positives = 66/129 (51%), Gaps = 13/129 (10%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQE-----RMEQE-RQEQEE--RE 222
E +R+ + Q ++EEEL++EEE+ + R QE R E+E +QE+E+ RE
Sbjct: 1039 EKRRLQERE--RQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLRE 1096
Query: 223 RRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAI 282
+ R Q+ E R+++ L+ EE + +E+ R +E E ++ E +E +
Sbjct: 1097 EPEKRRRQERERQCREEEELQQEEEQLLREERE---KRRRQELERQYREEEEVQQEEEQL 1153
Query: 283 IAQRPDNPR 291
+ + P+ R
Sbjct: 1154 LREEPEKRR 1162
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/96 (29%), Positives = 55/96 (57%), Gaps = 10/96 (10%)
Query: 185 KKEEELRKEEERKKALDERLRFEQERMEQERQEQEERER--RYREREQQIEEHRRKQQTL 242
++E +LR EE +++ ++R E+E EQ R+++ ERE+ ++ E E+Q++ R QQ
Sbjct: 793 QRERQLRAEERQQR--EQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQ 850
Query: 243 EAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEE 278
E E+ + +E+ R +E+ +K ++EE
Sbjct: 851 EEEDGLQEDQER------RRSQEQRRDQKWRWQLEE 880
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 12/109 (11%)
Query: 177 REQFWEQAKKEEELRKEEERKKALDER--LRFEQERMEQERQ-----EQEERERRYRERE 229
+E + ++EE+ R+ E R + L+E R Q+R EQER+ EQ E++ R +R+
Sbjct: 106 KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRD 165
Query: 230 QQIEEH---RRKQQTLEAEEAKRRLKEQSIFGDHRDEE--EETHMKKSE 273
+Q + R++Q+ E EE + ++ H EE +E +++ E
Sbjct: 166 RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRE 214
Score = 44.3 bits (103), Expect = 4e-04
Identities = 30/116 (25%), Positives = 61/116 (52%), Gaps = 8/116 (6%)
Query: 171 EMKRINREQFWEQAKKEEELRKEEERKKALDERLRFE-QERMEQERQE-------QEERE 222
E KR RE + ++E R+++E ++ D +++ +E+ E+ RQ +E+RE
Sbjct: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
Query: 223 RRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEE 278
R+ R E+Q E R + E E+ +R+ +E+ +EEE+ ++ +++E
Sbjct: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE 851
Score = 43.1 bits (100), Expect = 8e-04
Identities = 40/147 (27%), Positives = 72/147 (48%), Gaps = 20/147 (13%)
Query: 173 KRINREQFW--EQAKKEEELRKEEERKKAL---DERLRFEQERMEQERQEQE----ERER 223
+R REQ + E+ +KE+ R+ ER+K L +E + ++ Q+ QE+E E +
Sbjct: 802 ERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQE 861
Query: 224 RYREREQ--------QIEEHR-RKQQTLEAEEA--KRRLKEQSIFGDHRDEEEETHMKKS 272
R R +EQ Q+EE R R++ TL A+ A ++ KEQ + + +E + +K
Sbjct: 862 RRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKR 921
Query: 273 ESEVEEAAAIIAQRPDNPREFFKQQER 299
+ +E ++ E ++ER
Sbjct: 922 RRQEQERQYREEEQLQQEEEQLLREER 948
Score = 43.1 bits (100), Expect = 8e-04
Identities = 34/95 (35%), Positives = 51/95 (53%), Gaps = 12/95 (12%)
Query: 186 KEEELRKEEERKKALDERLR--------FEQERMEQERQE--QEERERRYREREQQI-EE 234
+EE+L+ EE+ ++ ER R QE+ +E QE QEE ++R +ERE+++ EE
Sbjct: 1824 EEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREE 1883
Query: 235 HRRKQQTLEAEEAK-RRLKEQSIFGDHRDEEEETH 268
H R+QQ E + +K Q G R E TH
Sbjct: 1884 HIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTH 1918
Score = 42.7 bits (99), Expect = 0.001
Identities = 44/177 (24%), Positives = 82/177 (46%), Gaps = 28/177 (15%)
Query: 146 HRLRLREDENAEPVGTTYQKTDAAV-EMKRINREQFWEQAKKEEELRKEEERKKALDERL 204
H L +++ + E +Q+ D E +++ RE EQ + + RK +E K+ L E
Sbjct: 1269 HLLGEQQERDREQERRRWQQRDRHFPEEEQLERE---EQKEAKRRDRKSQEEKQLLREER 1325
Query: 205 RFEQERMEQER----QEQE------------ERERRYREREQQIEEHRRK----QQTLEA 244
++ R E +R +EQ ER+R++RE E + +E RK +Q L
Sbjct: 1326 EEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR 1385
Query: 245 EEAKRR-LKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERV 300
+E +R+ LKE+ R +E E +++ R + R+F +++++V
Sbjct: 1386 QERERKFLKEEQ---QLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQV 1439
Score = 41.2 bits (95), Expect = 0.003
Identities = 29/83 (34%), Positives = 48/83 (57%), Gaps = 10/83 (12%)
Query: 177 REQFWEQAKKEEELRKE-----EERKKALDERLRFEQERMEQERQEQEERERRYREREQQ 231
REQ Q + EE ++E EE +K R R E+E+ Q +E+E+ +R RER QQ
Sbjct: 791 REQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQR--RERAQQ 848
Query: 232 IEEHRRKQQTLEAEEAKRRLKEQ 254
++E ++ L+ ++ +RR +EQ
Sbjct: 849 LQE---EEDGLQEDQERRRSQEQ 868
Score = 40.0 bits (92), Expect = 0.007
Identities = 27/106 (25%), Positives = 58/106 (54%), Gaps = 6/106 (5%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQ 208
+LR++ + + + E +++ E+ ++ ++E + + E + A E+ R E+
Sbjct: 1802 QLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREE 1861
Query: 209 ERMEQERQEQ--EERERRYRE---REQQIEEHRRKQ-QTLEAEEAK 248
+ + QE +++ +ERER+ RE R QQ EE R +Q ++++E K
Sbjct: 1862 QELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
Score = 38.1 bits (87), Expect = 0.026
Identities = 41/169 (24%), Positives = 79/169 (46%), Gaps = 23/169 (13%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQ 208
R R+ E + +K E +R + + WE K+ + K +E+ R +
Sbjct: 1195 RERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLE 1254
Query: 209 ERMEQERQEQE-------ERERRYRERE----QQIEEHRRKQQTLEAE---EAKRR---- 250
+ ++RQ Q+ E++ R RE+E QQ + H +++ LE E EAKRR
Sbjct: 1255 DSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKS 1314
Query: 251 LKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQER 299
+E+ + + R EE+ ++++ + E ++ +R + P ++QER
Sbjct: 1315 QEEKQLLREER--EEKRRRQETDRKFREEEQLLQEREEQP---LRRQER 1358
Score = 36.6 bits (83), Expect = 0.074
Identities = 24/82 (29%), Positives = 46/82 (56%), Gaps = 8/82 (9%)
Query: 200 LDERLRFE---QERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSI 256
LDE R +E + Q+R+ QEE +RR+ R++Q+EE +++ + +E +R L E
Sbjct: 95 LDEEKRARCDGKESLLQDRR-QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAE--- 150
Query: 257 FGDHRDEEEETHMKKSESEVEE 278
G+ + E++E ++ +E
Sbjct: 151 -GEEQSEKQERLEQRDRQRRDE 171
Score = 35.0 bits (79), Expect = 0.22
Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 19/99 (19%)
Query: 193 EEERKKALDERLRFEQERMEQERQ----------EQEERERRYREREQQI------EEHR 236
+EE++ D + Q+R ++E Q E+E +RR ++R++Q EE
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQS 155
Query: 237 RKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESE 275
KQ+ LE + +RR +E R E +E +++E E
Sbjct: 156 EKQERLEQRDRQRRDEE---LWRQRQEWQEREERRAEEE 191
Score = 33.9 bits (76), Expect = 0.48
Identities = 20/88 (22%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 193 EEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLK 252
EE+R + + + R E++++ E R+R+ E Q +R++Q E E + + +
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
Query: 253 EQSIF--GDHRDEEEETHMKKSESEVEE 278
+Q D + +EE ++ E + E
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQERE 184
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 63.5 bits (153), Expect = 6e-10
Identities = 40/174 (22%), Positives = 89/174 (51%), Gaps = 18/174 (10%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKK----EEELRKEEERKKALDERL 204
++RE+E + +++ E K +E+ W Q +K EE++RK+EE+ +E++
Sbjct: 512 KIREEEKRQEQEEMWRQ-----EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKM 566
Query: 205 RFEQERMEQERQEQEERERRYREREQQIEEHRRK-----QQTLEAEEAKRRLKEQSIFGD 259
++E++ ++ ++ +E + RE+E++I E K + T E EE +E+ +
Sbjct: 567 HDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 626
Query: 260 HRDEEEETHMKKSESEVEEAAAIIAQRPDNPRE----FFKQQERVASASAGSCD 309
+ +E+E M++ E ++ E I ++ + RE +Q+E++ C+
Sbjct: 627 EKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 680
Score = 61.6 bits (148), Expect = 2e-09
Identities = 70/293 (23%), Positives = 127/293 (43%), Gaps = 27/293 (9%)
Query: 18 EEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAAL 77
EE+ +E A LY ++LK LQE E++K +VK+ + L
Sbjct: 257 EELTKERDALSLELYRNTITDEELK---EKNAKLQEKLQLVESEKSEIQL-NVKELKRKL 312
Query: 78 PKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGL 137
+ L+ +P + A A H+ K Q V + A E+ + Q+ +
Sbjct: 313 ERAKLL------LPQQQLQAEADHLGKE---LQSVSAKLQAQVEENELWNRLNQQQEEKM 363
Query: 138 ARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERK 197
R + + E E + +K E R E WE KEE++R++EE
Sbjct: 364 WRQEEKI-QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE---KEEKMRRQEEMM 419
Query: 198 KALDERLRFEQERM--------EQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKR 249
+E++R ++E M E E + E+ + R +E ++Q EE R+Q+ + +EAK
Sbjct: 420 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 479
Query: 250 RLKEQSI-FGDHRDEEEETHMKKSESEVEEAAAI-IAQRPDNPREFFKQQERV 300
+E+ I + + E+E M + E ++ E I ++ E ++Q+E++
Sbjct: 480 WRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 532
Score = 57.8 bits (138), Expect = 3e-08
Identities = 32/133 (24%), Positives = 77/133 (57%), Gaps = 2/133 (1%)
Query: 147 RLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRF 206
++R +E++ E T ++ + E + EQ + ++EE++R++EE+ + ++++R
Sbjct: 593 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIRE 652
Query: 207 EQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEE 266
++E++ ++ + +E+E + E+E+++ E K Q E EE RR +E+ + R ++E
Sbjct: 653 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ--EQEEKMRRQEEKMWEQEVRLRQQE 710
Query: 267 THMKKSESEVEEA 279
M++ + +E A
Sbjct: 711 EKMQEHQEHLEAA 723
Score = 56.2 bits (134), Expect = 9e-08
Identities = 47/163 (28%), Positives = 86/163 (52%), Gaps = 16/163 (9%)
Query: 147 RLRLREDENAEPVGTTYQKTDAAVE----MKRINREQFWEQAKKEEELRKEEERKKALDE 202
+L+ D + + + K A VE R+N++Q + ++EE++++ EE+ + +E
Sbjct: 323 QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE 382
Query: 203 RLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTL--EAEEAKRRLKEQSIFGDH 260
++R ++E++ +EQEE+ RR E + EE R+Q+ + E EE RR +E +
Sbjct: 383 KIREQEEKI----REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 438
Query: 261 --RDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVA 301
R+ EE+ H ++ E EE Q + RE K+QE+ A
Sbjct: 439 KIRELEEKMHEQEKIREQEEK----RQEEEKIREQEKRQEQEA 477
Score = 55.8 bits (133), Expect = 1e-07
Identities = 39/136 (28%), Positives = 76/136 (55%), Gaps = 10/136 (7%)
Query: 171 EMKRINREQFWEQAKK----EEELRKEEERKKALDERLRFEQE--RMEQERQEQEERERR 224
E ++ + W Q +K EE++R++EE+ +E++ EQE R E++RQEQEE R+
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIH-EQEKIREEEKRQEQEEMWRQ 528
Query: 225 YREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIA 284
+ +Q E R+K++ E EE R+ +E+ + + ++E +++ E +V I
Sbjct: 529 EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIR 588
Query: 285 QRPDNPREFFKQQERV 300
++ + RE Q+E++
Sbjct: 589 EQEEKIRE---QEEKI 601
Score = 55.8 bits (133), Expect = 1e-07
Identities = 42/155 (27%), Positives = 84/155 (54%), Gaps = 15/155 (9%)
Query: 149 RLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQ 208
++R+ E E + +K E R E+ W Q EE++R++EE+ + +E++R EQ
Sbjct: 551 KIRKQE--EKMWRQEEKMHDQEEKIREQEEKVWRQ---EEKIREQEEKIREQEEKIR-EQ 604
Query: 209 ERMEQERQ----EQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEE 264
E M QE++ EQEE+ E+ Q+ EE R+Q+ + E +++++EQ + + E
Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE-KIREQEKKIREQ----EEKIRE 659
Query: 265 EETHMKKSESEVEEAAAIIAQRPDNPREFFKQQER 299
+E M++ E ++ E + ++ + +E ++ R
Sbjct: 660 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 694
Score = 53.9 bits (128), Expect = 4e-07
Identities = 43/161 (26%), Positives = 82/161 (50%), Gaps = 14/161 (8%)
Query: 151 REDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQER 210
+E++ E +++ + E + REQ E+ +++EE+ +E+E K E EQE
Sbjct: 569 QEEKIREQEEKVWRQEEKIREQEEKIREQE-EKIREQEEMTQEQEEKMGEQEEKMCEQEE 627
Query: 211 MEQE------RQEQE--ERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRD 262
QE RQE++ E+E++ RE+E++I E Q E EE +E+ + +
Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ--EQEEKMWEQEEKMCEQEEKM 685
Query: 263 EEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASA 303
+E+E M++ E ++ E + Q+ + +E QE + +A
Sbjct: 686 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQE---HQEHLEAA 723
Score = 52.4 bits (124), Expect = 1e-06
Identities = 35/141 (24%), Positives = 70/141 (49%), Gaps = 16/141 (11%)
Query: 171 EMKRINREQFWEQAKKEEELRK---EEERKKALDERLRFEQERMEQERQEQEE-----RE 222
E R E WE+ +K EL + E+E+ + +E+ + E++ EQE+++++E +E
Sbjct: 424 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 483
Query: 223 RRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAI 282
+ RE+E++I E K E ++ EQ + +E+ M + E ++ E I
Sbjct: 484 EKIREQEEKIREQEEKMWRQE-----EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 538
Query: 283 IAQRP---DNPREFFKQQERV 300
Q+ + + KQ+E++
Sbjct: 539 WRQKEKIHEQEEKIRKQEEKM 559
Score = 50.4 bits (119), Expect = 5e-06
Identities = 34/135 (25%), Positives = 74/135 (54%), Gaps = 8/135 (5%)
Query: 171 EMKRINREQFWEQAKK--EEELRKEEERKKALDERLRFEQERMEQE---RQEQEERERRY 225
E R E+ W Q +K E+E +EEE+++ +E R E++ EQE RQ+++ E+
Sbjct: 491 EKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEE 550
Query: 226 REREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQ 285
+ R+Q+ + R++++ + EE R +E+ + + E+E +++ E ++ E + +
Sbjct: 551 KIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQE 610
Query: 286 RPDNPREFFKQQERV 300
+ + E Q+E++
Sbjct: 611 QEEKMGE---QEEKM 622
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 63.5 bits (153), Expect = 6e-10
Identities = 65/255 (25%), Positives = 98/255 (38%), Gaps = 40/255 (15%)
Query: 178 EQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRR 237
E+ E+ ++EEE +EEE ++ +E E+E E+E +E+EE E + E E ++EE
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE 947
Query: 238 KQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRP---DNPREFF 294
++ E EE +E E+ + EVEE A P P
Sbjct: 948 EEDEEEEEEL--------------EEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPP 993
Query: 295 KQQERVASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDSST---ASTPVAEQ 351
K Q +V PG+ + APT P PS +P A
Sbjct: 994 KVQPEPEPEPGLLLEV-----EEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGP 1048
Query: 352 IERALDEVTSSQPPPL-------------PPPPPPAQETQEPSPILDS--EETRAAAPQA 396
+ L E S PP L PPP PA+E E ++ E+ +
Sbjct: 1049 PPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAM 1108
Query: 397 WAGPMEEPPQAQAPP 411
A ++ PP + PP
Sbjct: 1109 LADFIDCPPDDEKPP 1123
Score = 50.4 bits (119), Expect = 5e-06
Identities = 61/237 (25%), Positives = 95/237 (40%), Gaps = 16/237 (6%)
Query: 199 ALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFG 258
AL+E L E +E+EE E E E++ EE +++ E E + +E+ F
Sbjct: 873 ALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFE 932
Query: 259 DHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRP 318
+ +EEE ++ E E EE + + D EF V + +P P P
Sbjct: 933 EEFEEEEGELEEEEEEEDEEEEEELEEVED--LEFGTAGGEVEEGAPPPPTLP-PALPPP 989
Query: 319 GSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQ 378
+S ++ P P P P P E+ ER D + P LP +E +
Sbjct: 990 ----ESPPKVQPEPEP--EPGLLLEVEEPGTEE-ERGADTAPTLAPEALPSQGEVEREGE 1042
Query: 379 EPS----PILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAEDLMFMESAEQAV 431
P+ P EE +A P E+ PP P +PAE+ M E+ +A+
Sbjct: 1043 SPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPP--PETPAEEEMETETEAEAL 1097
Score = 48.1 bits (113), Expect = 2e-05
Identities = 37/129 (28%), Positives = 47/129 (36%), Gaps = 24/129 (18%)
Query: 310 VPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDSSTASTP--------------VAEQIERA 355
+P P NHR GS+ D + TP PT P ++ P V +E
Sbjct: 724 LPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESD 783
Query: 356 LDEVTSSQPPPLPPPPPPAQETQEPSPILDSEETRAAAP----------QAWAGPMEEPP 405
D+ P LPP PPP P PI + A+ P A GP+ PP
Sbjct: 784 SDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPP 843
Query: 406 QAQAPPRGP 414
P GP
Sbjct: 844 PPPPPVPGP 852
Score = 45.4 bits (106), Expect = 2e-04
Identities = 81/302 (26%), Positives = 102/302 (33%), Gaps = 61/302 (20%)
Query: 360 TSSQPPPLPPPPPP----AQETQEPSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPG 415
T P P+PPP P A P P+ +A P AGPM P P PG
Sbjct: 644 TCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPM--PSAGPVPSARPG 701
Query: 416 SPAEDLMFMESAEQAVLAAP----VEPATADATEIHDAADTIE---------TDTATADT 462
P +A L+ P V P E H A + T D
Sbjct: 702 PPT-------TANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDE 754
Query: 463 TVANNVP-PA--------ATSLIDLWPGNGEGASTLQGE---PRAPTPPSG--------T 502
T VP PA A+ + + + + + E P P PPSG T
Sbjct: 755 TFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPT 814
Query: 503 EVTLAEVPLLDEVAPEPLLPAGEGCATLLNFDELPEP-PATFCDPEEV-EGEPLAAPQTP 560
A P+ + PE LPA G P P P T P+ V EG P P
Sbjct: 815 GPPTASPPVPAKEEPEE-LPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTP-GGGGPP 872
Query: 561 TLPSAL-----------EELEQEQEPEPHLLTNGETTQKEGTQASEGYFSQSQEEEFAQS 609
L L EE E+E+E E E +E + E YF + +EEE
Sbjct: 873 ALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFE 932
Query: 610 EE 611
EE
Sbjct: 933 EE 934
Score = 45.1 bits (105), Expect = 2e-04
Identities = 74/323 (22%), Positives = 103/323 (31%), Gaps = 43/323 (13%)
Query: 334 PTRSPSDSSTASTPV-AEQIERALDEVTSSQPPPLPPPPP-PAQETQEPSPILDSEETRA 391
P +P+ TAS PV A++ L PPP PPPPP P T P ++
Sbjct: 809 PPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGG 868
Query: 392 AAPQAWAGPM------------EEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPA 439
P A + EE + + ED E E+ E
Sbjct: 869 GGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEE 928
Query: 440 TADATEIHDAADTIETDTATADTTVANNVPPAATSLIDLWPGNGEGASTLQGEPRAPTPP 499
E + +E + D + + DL G G +G P PT P
Sbjct: 929 EEFEEEFEEEEGELEEEEEEEDEEEEEEL----EEVEDLEFGTA-GGEVEEGAPPPPTLP 983
Query: 500 SGTEVTLAEVPLLDEVAPEPLL-----------PAGEGCATLLNFDELP---------EP 539
+ + E PEP L G A L + LP E
Sbjct: 984 PALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGES 1043
Query: 540 PATFCDPEEVEGEPLAAPQTPTLPSALEELEQEQEPEPHLLTNGE---TTQKEGTQASEG 596
PA P+E+ E +AP T L E+ + +P P E T+ E Q E
Sbjct: 1044 PAAGPPPQELVEEEPSAPPT-LLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQ 1102
Query: 597 YFSQSQEEEFAQSEELCAKAPPP 619
+ + +F K PPP
Sbjct: 1103 DDTAAMLADFIDCPPDDEKPPPP 1125
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 63.5 bits (153), Expect = 6e-10
Identities = 57/234 (24%), Positives = 102/234 (43%), Gaps = 21/234 (8%)
Query: 134 SNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKE 193
+ L+ LS RL+ +E+ E ++ + E REQ ++ E LRK+
Sbjct: 325 NQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQ 384
Query: 194 EERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKE 253
E+R + +ERLR E+ER++++ + ++E R ++E+++++ + + + ++L E
Sbjct: 385 EQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAE 444
Query: 254 -QSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPR-EFFKQQERVASASAGSCDVP 311
Q F D +E KKS ++E+ + ++ D E Q + +P
Sbjct: 445 PQCSFEDLNNE------KKSALQLEQQVKELQEKLDEEHLEAASHQNQQLETQLSLVALP 498
Query: 312 SPFNHRPGSHLDSHRRMAPTPIP-----------TRSPSDSSTASTPVAEQIER 354
+ G HLDS AP P P T S D EQ+ER
Sbjct: 499 GEGD--GGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQVER 550
Score = 44.3 bits (103), Expect = 4e-04
Identities = 37/156 (23%), Positives = 82/156 (52%), Gaps = 9/156 (5%)
Query: 152 EDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKK-EEELRKEEERKKALDERLRFEQER 210
+++ AEP + VE + + ++ + E +L+ + E +AL + +++R
Sbjct: 279 KNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQR 338
Query: 211 M-EQERQEQEERERRYREREQQIEEHRR---KQQTLEAEEAKRRLKEQSI-FGDHRDEEE 265
+ EQE +E+ +R RE+E+ E++ R +Q+TL+ + + R +EQ + + R +E
Sbjct: 339 LQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKE 398
Query: 266 ETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVA 301
E ++K E + + + ++ + + KQ+ER+A
Sbjct: 399 EERLQKQEKRLWDQEERLWKKEERLQ---KQEERLA 431
Score = 32.7 bits (73), Expect = 1.1
Identities = 47/235 (20%), Positives = 88/235 (37%), Gaps = 31/235 (13%)
Query: 158 PVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKE-----EERKKALDERLRFEQERME 212
P + YQ+ A+E + Q E + ++ +K+ EE KK +E + + ER+E
Sbjct: 66 PGDSQYQELAVALESSSVTISQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMERLE 125
Query: 213 Q------ERQEQE------ERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDH 260
E+ + + +R R+ E E + R + +E +R L S
Sbjct: 126 TINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQE 185
Query: 261 RDEEE---ETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHR 317
D E +++ + + A++ E KQ + A H
Sbjct: 186 EDRSSSCREAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERDEYA---------KHI 236
Query: 318 PGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVTS--SQPPPLPPP 370
G RM + R+ + +++ER+L E+ + ++PP L PP
Sbjct: 237 KGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPP 291
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,881,595
Number of Sequences: 37866
Number of extensions: 2049020
Number of successful extensions: 54960
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1145
Number of HSP's successfully gapped in prelim test: 2000
Number of HSP's that attempted gapping in prelim test: 15981
Number of HSP's gapped (non-prelim): 17893
length of query: 649
length of database: 18,247,518
effective HSP length: 109
effective length of query: 540
effective length of database: 14,120,124
effective search space: 7624866960
effective search space used: 7624866960
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.