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Search of human proteins with 18375603
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18375603 T-box 22 isoform 1 [Homo sapiens]
(520 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|158187509 T-box 22 isoform 1 [Homo sapiens] 1063 0.0
gi|18375603 T-box 22 isoform 1 [Homo sapiens] 1063 0.0
gi|158187511 T-box 22 isoform 2 [Homo sapiens] 830 0.0
gi|55770860 T-box 15 [Homo sapiens] 375 e-104
gi|122937456 T-box 18 [Homo sapiens] 353 3e-97
gi|117676399 T-box transcription factor TBX20 [Homo sapiens] 251 1e-66
gi|5174711 T-box 1 isoform B [Homo sapiens] 228 1e-59
gi|18104952 T-box 1 isoform C [Homo sapiens] 223 3e-58
gi|18104950 T-box 1 isoform A [Homo sapiens] 223 3e-58
gi|32567784 T-box 10 [Homo sapiens] 218 8e-57
gi|18201900 T-box 6 [Homo sapiens] 213 3e-55
gi|18129690 T-box 4 [Homo sapiens] 211 1e-54
gi|197333868 T-box 2 [Homo sapiens] 209 4e-54
gi|47419905 T-box 3 protein isoform 1 [Homo sapiens] 204 1e-52
gi|18201896 T-box 5 isoform 2 [Homo sapiens] 200 2e-51
gi|18201892 T-box 5 isoform 1 [Homo sapiens] 200 2e-51
gi|31652232 T-box 5 isoform 1 [Homo sapiens] 200 2e-51
gi|18201894 T-box 5 isoform 3 [Homo sapiens] 198 1e-50
gi|47419907 T-box 3 protein isoform 2 [Homo sapiens] 193 4e-49
gi|122937388 MAX gene associated [Homo sapiens] 186 3e-47
gi|4827024 T-box 19 [Homo sapiens] 175 8e-44
gi|22538470 eomesodermin [Homo sapiens] 174 2e-43
gi|5730081 T-box, brain, 1 [Homo sapiens] 173 3e-43
gi|7019549 T-box 21 [Homo sapiens] 169 6e-42
gi|4507339 transcription factor T [Homo sapiens] 167 2e-41
gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens] 36 0.075
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 36 0.075
gi|24430146 nucleoporin 153kDa [Homo sapiens] 36 0.097
gi|169167062 PREDICTED: hypothetical protein LOC285556 [Homo sap... 35 0.13
gi|113416182 PREDICTED: hypothetical protein LOC285556 [Homo sap... 35 0.13
>gi|158187509 T-box 22 isoform 1 [Homo sapiens]
Length = 520
Score = 1063 bits (2749), Expect = 0.0
Identities = 520/520 (100%), Positives = 520/520 (100%)
Query: 1 MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEK 60
MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEK
Sbjct: 1 MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEK 60
Query: 61 QPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRR 120
QPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRR
Sbjct: 61 QPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRR 120
Query: 121 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP 180
MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP
Sbjct: 121 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP 180
Query: 181 DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS 240
DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS
Sbjct: 181 DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS 240
Query: 241 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPW 300
LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPW
Sbjct: 241 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPW 300
Query: 301 RPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCP 360
RPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCP
Sbjct: 301 RPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCP 360
Query: 361 EAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTN 420
EAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTN
Sbjct: 361 EAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTN 420
Query: 421 SKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFS 480
SKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFS
Sbjct: 421 SKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFS 480
Query: 481 MPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL 520
MPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL
Sbjct: 481 MPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL 520
>gi|18375603 T-box 22 isoform 1 [Homo sapiens]
Length = 520
Score = 1063 bits (2749), Expect = 0.0
Identities = 520/520 (100%), Positives = 520/520 (100%)
Query: 1 MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEK 60
MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEK
Sbjct: 1 MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEK 60
Query: 61 QPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRR 120
QPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRR
Sbjct: 61 QPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRR 120
Query: 121 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP 180
MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP
Sbjct: 121 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP 180
Query: 181 DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS 240
DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS
Sbjct: 181 DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS 240
Query: 241 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPW 300
LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPW
Sbjct: 241 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPW 300
Query: 301 RPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCP 360
RPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCP
Sbjct: 301 RPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCP 360
Query: 361 EAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTN 420
EAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTN
Sbjct: 361 EAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTN 420
Query: 421 SKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFS 480
SKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFS
Sbjct: 421 SKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFS 480
Query: 481 MPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL 520
MPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL
Sbjct: 481 MPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL 520
>gi|158187511 T-box 22 isoform 2 [Homo sapiens]
Length = 400
Score = 830 bits (2145), Expect = 0.0
Identities = 400/400 (100%), Positives = 400/400 (100%)
Query: 121 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP 180
MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP
Sbjct: 1 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP 60
Query: 181 DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS 240
DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS
Sbjct: 61 DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS 120
Query: 241 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPW 300
LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPW
Sbjct: 121 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPW 180
Query: 301 RPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCP 360
RPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCP
Sbjct: 181 RPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCP 240
Query: 361 EAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTN 420
EAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTN
Sbjct: 241 EAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTN 300
Query: 421 SKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFS 480
SKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFS
Sbjct: 301 SKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFS 360
Query: 481 MPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL 520
MPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL
Sbjct: 361 MPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL 400
>gi|55770860 T-box 15 [Homo sapiens]
Length = 496
Score = 375 bits (964), Expect = e-104
Identities = 219/449 (48%), Positives = 281/449 (62%), Gaps = 39/449 (8%)
Query: 90 KDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDS 149
++IQ+ELQ ++LWKRFHDIGTEMIITKAGRRMFP++RVK+ GLDP +QY++A+D+VPVD+
Sbjct: 5 EEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDN 64
Query: 150 KRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDK 209
KRYRYVYHSS+WMVAGN D + PR Y+HPDS SG+TWMRQ++SFD++KLTNNE+DD+
Sbjct: 65 KRYRYVYHSSKWMVAGNADS-PVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQ 123
Query: 210 GHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPT-EGVKTFSFKETEFTTVTAYQNQQIT 268
GHIIL SMHKY+PRVHVI + S DLS + +P +GVKTF+F ET FTTVTAYQNQQIT
Sbjct: 124 GHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQIT 183
Query: 269 KLKIERNPFAKGFRDTGRNRGVLDGLLETYP-WRPSF-TLDFKTFGA--DTQSGSSGSSP 324
+LKI+RNPFAKGFRD+GRNR L+ ++ETY WRP TL F+ F Q GS+G+SP
Sbjct: 184 RLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSP 243
Query: 325 VTSSGGAPSPLNS--LLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNL---PLCYKICPTN 379
TSS G PSP S LLSP C P FHL ++ + C E+ L N+NL P C +
Sbjct: 244 TTSSTGTPSPSASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAA 303
Query: 380 FWQQQPLVLPAPERLASSNSSQ----------------SLAPLMMEVPMLSSLGVTNSKS 423
L RL S +S S P +P S + +
Sbjct: 304 LQSYPGLSDSGYNRLQSGTTSATQPSETFMPQRTPSLISGIPTPPSLPGNSKMEAYGGQL 363
Query: 424 GSSEDSSDQY-LQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNF--- 479
GS S QY +QA N+ + G+ +S + S H Y+ Y YNF
Sbjct: 364 GSFPTSQFQYVMQAGNAASSSSSPHMFGGSHMQQSSYN----AFSLHNPYNLYGYNFPTS 419
Query: 480 ----SMPSRLISGSNHLKVNDDSQVSFGE 504
+ P +L + + L + S +FGE
Sbjct: 420 PRLAASPEKLSASQSTLLCSSPSNGAFGE 448
>gi|122937456 T-box 18 [Homo sapiens]
Length = 607
Score = 353 bits (905), Expect = 3e-97
Identities = 231/537 (43%), Positives = 305/537 (56%), Gaps = 63/537 (11%)
Query: 3 LSSRARAFSVEALVGRPSKRKLQDP---IQAEQPELR------EKKGGEEEEERRSSAAG 53
LS +A AFSVEAL+G +++LQ + AE+ + GG E+ G
Sbjct: 13 LSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAAGAVDDGGCSRGGGAGEKGSSEGDEG 72
Query: 54 KSEPLEKQPKTEPSTS-------ASSGCGSD-------------SGYGNSSESLEEKDI- 92
+ P + P+ S A+ GC S G+ + SL
Sbjct: 73 AALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKGSPARSLARPGTP 132
Query: 93 -------QMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVV 145
+++LQG+ELWKRFH+IGTEMIITKAGRRMFP++RVK+ GLDP +QY++A+D+V
Sbjct: 133 LPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIV 192
Query: 146 PVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNE 205
PVD+KRYRYVYHSS+WMVAGN D + PR Y+HPDSP SGETWMRQ+ISFD++KLTNNE
Sbjct: 193 PVDNKRYRYVYHSSKWMVAGNADS-PVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNE 251
Query: 206 MDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPT-EGVKTFSFKETEFTTVTAYQN 264
+DD+GHIIL SMHKY+PRVHVI + DLS I+ +P+ EGVK FSF ET FTTVTAYQN
Sbjct: 252 LDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETVFTTVTAYQN 311
Query: 265 QQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYP-WRPSF-TLDFKTFGADTQSGSSGS 322
QQIT+LKI+RNPFAKGFRD+GRNR L+ L+E+Y WRPS TL F+ + G++ S
Sbjct: 312 QQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPGIPKQGNASS 371
Query: 323 SPVT--SSGGAPSPLNSLLS-PLCFSPMFHL--PTSSLGMPCPEAYLPNVNLPLCYKICP 377
S + + G P+ LLS C SP FHL TS L P Y L
Sbjct: 372 STLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNTSQLCSLAPADYSACARSGLTLNRYS 431
Query: 378 TNFWQQQPLVLPAPERLASSNSSQSLAP--LMMEVPMLSSLGVTNSKSGSSEDS-----S 430
T+ L ++ + ++ AP V + SS V S G+ D+ +
Sbjct: 432 TS--------LAETYNRLTNQAGETFAPPRTPSYVGVSSSTSVNMSMGGTDGDTFSCPQT 483
Query: 431 DQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSF--HPSYDFYRYNFSMPSRL 485
+Q + Q+ Y + SP + + T + +F H Y YNFS +L
Sbjct: 484 SLSMQISGMSPQLQYIMPSPSSNAFATNQTHQGSYNTFRLHSPCALYGYNFSTSPKL 540
>gi|117676399 T-box transcription factor TBX20 [Homo sapiens]
Length = 447
Score = 251 bits (641), Expect = 1e-66
Identities = 161/397 (40%), Positives = 216/397 (54%), Gaps = 66/397 (16%)
Query: 3 LSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEP-LEKQ 61
LSSRA AFS+ AL+ GG +E+E + E +EK
Sbjct: 11 LSSRANAFSIAALMS---------------------SGGSKEKEATENTIKPLEQFVEKS 49
Query: 62 PKTEP-----STSASSGCGSDSGYGNSSESL---------------EEKDIQMELQGSEL 101
+P S A G SG SS SL E I L+ EL
Sbjct: 50 SCAQPLGELTSLDAHGEFGGGSGSSPSSSSLCTEPLIPTTPIIPSEEMAKIACSLETKEL 109
Query: 102 WKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQW 161
W +FH++GTEMIITK+GRRMFP++RV G+DP +Y V +D+VPVD+KRYRY YH S W
Sbjct: 110 WDKFHELGTEMIITKSGRRMFPTIRVSFSGVDPEAKYIVLMDIVPVDNKRYRYAYHRSSW 169
Query: 162 MVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYK 221
+VAG D + R YVHPDSP +GE ++Q++SF+++KLTNNE+D GHIIL SMHKY+
Sbjct: 170 LVAGKADP-PLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQ 228
Query: 222 PRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGF 281
PRVH+I++ + + +L +E +TF F ET FT VTAYQNQ ITKLKI+ NPFAKGF
Sbjct: 229 PRVHIIKKKDHT--ASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGF 286
Query: 282 RDTGR----NRGVLDGLLETYPWRPSFTLDFKTFGA--DTQSGSSGSSPVTSSGGAPS-- 333
RD+ R R ++ L++ + + S +T+G D S ++P S S
Sbjct: 287 RDSSRLTDIERESVESLIQKHSYARS---PIRTYGGEEDVLGDESQTTPNRGSAFTTSDN 343
Query: 334 -PLNSLLSPLCFSPMFHLP---------TSSLGMPCP 360
L+S +S P F P T+S+ P P
Sbjct: 344 LSLSSWVSSSSSFPGFQHPQSLTALGTSTASIATPIP 380
>gi|5174711 T-box 1 isoform B [Homo sapiens]
Length = 372
Score = 228 bits (580), Expect = 1e-59
Identities = 128/301 (42%), Positives = 167/301 (55%), Gaps = 14/301 (4%)
Query: 51 AAGKSEPLEKQPKTEPSTSASSGCGSDSGYGNS---------SESLEEKDIQMELQGSEL 101
A G P P + +A+S G G S ++ + + ++L+ L
Sbjct: 60 APGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKAL 119
Query: 102 WKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQW 161
W F+ +GTEMI+TKAGRRMFP+ +VK+ G+DP Y + +D VPVD KRYRY +HSS W
Sbjct: 120 WDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSW 179
Query: 162 MVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYK 221
+VAG D R + HPDSP G WM+QI+SFD++KLTNN +DD GHIIL SMH+Y+
Sbjct: 180 LVAGKADP-ATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQ 238
Query: 222 PRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGF 281
PR HV+ D + E KTF F+ET FT VTAYQN +IT+LKI NPFAKGF
Sbjct: 239 PRFHVVYVDPRKD---SEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGF 295
Query: 282 RDTGRNRGVLDGLLETYPWRPSFTLDFKTFGADTQ-SGSSGSSPVTSSGGAPSPLNSLLS 340
RD + P +F + TQ SG+ SG P L+ LL
Sbjct: 296 RDCDPEDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGLVTEGSGLQPGLLDVLLK 355
Query: 341 P 341
P
Sbjct: 356 P 356
>gi|18104952 T-box 1 isoform C [Homo sapiens]
Length = 495
Score = 223 bits (569), Expect = 3e-58
Identities = 115/242 (47%), Positives = 149/242 (61%), Gaps = 13/242 (5%)
Query: 51 AAGKSEPLEKQPKTEPSTSASSGCGSDSGYGNS---------SESLEEKDIQMELQGSEL 101
A G P P + +A+S G G S ++ + + ++L+ L
Sbjct: 60 APGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKAL 119
Query: 102 WKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQW 161
W F+ +GTEMI+TKAGRRMFP+ +VK+ G+DP Y + +D VPVD KRYRY +HSS W
Sbjct: 120 WDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSW 179
Query: 162 MVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYK 221
+VAG D R + HPDSP G WM+QI+SFD++KLTNN +DD GHIIL SMH+Y+
Sbjct: 180 LVAGKADP-ATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQ 238
Query: 222 PRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGF 281
PR HV+ D + E KTF F+ET FT VTAYQN +IT+LKI NPFAKGF
Sbjct: 239 PRFHVVYVDPRKD---SEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGF 295
Query: 282 RD 283
RD
Sbjct: 296 RD 297
>gi|18104950 T-box 1 isoform A [Homo sapiens]
Length = 398
Score = 223 bits (569), Expect = 3e-58
Identities = 115/242 (47%), Positives = 149/242 (61%), Gaps = 13/242 (5%)
Query: 51 AAGKSEPLEKQPKTEPSTSASSGCGSDSGYGNS---------SESLEEKDIQMELQGSEL 101
A G P P + +A+S G G S ++ + + ++L+ L
Sbjct: 60 APGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKAL 119
Query: 102 WKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQW 161
W F+ +GTEMI+TKAGRRMFP+ +VK+ G+DP Y + +D VPVD KRYRY +HSS W
Sbjct: 120 WDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSW 179
Query: 162 MVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYK 221
+VAG D R + HPDSP G WM+QI+SFD++KLTNN +DD GHIIL SMH+Y+
Sbjct: 180 LVAGKADP-ATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQ 238
Query: 222 PRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGF 281
PR HV+ D + E KTF F+ET FT VTAYQN +IT+LKI NPFAKGF
Sbjct: 239 PRFHVVYVDPRKD---SEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGF 295
Query: 282 RD 283
RD
Sbjct: 296 RD 297
>gi|32567784 T-box 10 [Homo sapiens]
Length = 385
Score = 218 bits (556), Expect = 8e-57
Identities = 128/318 (40%), Positives = 178/318 (55%), Gaps = 23/318 (7%)
Query: 67 STSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVR 126
S++ + +G G + + +Q+E++ LW+ F+ +GTEMI+TKAGRRMFP +
Sbjct: 42 SSTGAQAVAEPTGQGPKNPRVSRVTVQLEMK--PLWEEFNQLGTEMIVTKAGRRMFPPFQ 99
Query: 127 VKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSG 186
VK+ G+D Y + +D +P+D KRYRY +HSS W+VAG D R + HPDSP G
Sbjct: 100 VKILGMDSLADYALLMDFIPLDDKRYRYAFHSSAWLVAGKADP-ATPGRVHFHPDSPAKG 158
Query: 187 ETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGV 246
WMRQI+SFD++KLTNN +DD GHIIL SMH+Y+PR HV+ D + E
Sbjct: 159 AQWMRQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVFVDPRKDSERYAQ---ENF 215
Query: 247 KTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNR-GVLDGLLETYPWRPSFT 305
K+F F ET+FT VTAYQN +IT+LKI NPFAKGFR++ + V L + P R +
Sbjct: 216 KSFIFTETQFTAVTAYQNHRITQLKIASNPFAKGFRESDLDSWPVAPRPLLSVPARSHSS 275
Query: 306 LDFKTFGADTQSGSSGSSPVTSSGGAPS--------PLNSLLSPLCFSP-----MFHLPT 352
L T + S+ P+ P LL+P + P ++
Sbjct: 276 LSPCVLKGATDREKDPNKASASTSKTPAWLHHQLLPPPEVLLAPATYRPVTYQSLYSGAP 335
Query: 353 SSLGMP--CPEAY-LPNV 367
S LG+P P Y LPN+
Sbjct: 336 SHLGIPRTRPAPYPLPNI 353
>gi|18201900 T-box 6 [Homo sapiens]
Length = 436
Score = 213 bits (542), Expect = 3e-55
Identities = 146/398 (36%), Positives = 195/398 (48%), Gaps = 62/398 (15%)
Query: 29 QAEQPELREKKGGEEEEERRSSAAGKSEPLEKQPKTEPSTSASSGCGSDSGYGNSSESLE 88
+ + P+L G E R +A L TEP+ SA S G
Sbjct: 40 ELDTPKLDCFLSGMEAAPRTLAAHPPLPLLPPAMGTEPAPSAPEALHSLPG--------- 90
Query: 89 EKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVD 148
+ + L+ ELWK F +GTEMIITKAGRRMFP+ RV V GLDP +Y +DV+PVD
Sbjct: 91 ---VSLSLENRELWKEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVD 147
Query: 149 SKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDD 208
RYR + +W +G + + R Y+HPDSP +G WMRQ +SF R+KLTN+ +D
Sbjct: 148 GARYR--WQGRRWEPSGKAEPR-LPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDP 204
Query: 209 KGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQIT 268
GH+IL SMHKY+PR+H++ +Q+ S G+ +F F ET F +VTAYQN QIT
Sbjct: 205 HGHLILHSMHKYQPRIHLVR------AAQLCSQHWGGMASFRFPETTFISVTAYQNPQIT 258
Query: 269 KLKIERNPFAKGFRDTGRN-------------RGVLDGLLETYPW--RPSFTLDFKTFGA 313
+LKI NPFAKGFR+ GRN RG E Y P D T G
Sbjct: 259 QLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPEPAATEAYGSGDTPGGPCD-STLGG 317
Query: 314 DTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCY 373
D + +P AP + +PLC G P EAYL + P +
Sbjct: 318 DIRESDPEQAP------APGEATAAPAPLC------------GGPSAEAYLLH---PAAF 356
Query: 374 KICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVP 411
P++ + P AP+ S S + +E+P
Sbjct: 357 HGAPSHLPTRSPSFPEAPD----SGRSAPYSAAFLELP 390
>gi|18129690 T-box 4 [Homo sapiens]
Length = 545
Score = 211 bits (537), Expect = 1e-54
Identities = 119/257 (46%), Positives = 159/257 (61%), Gaps = 17/257 (6%)
Query: 35 LREKKGGEEEEERRS--------SAAGKSEPLEKQPKTEPSTSASS-GCGSDSGYGNSSE 85
L++K E EE R+ SAA EP P + S G G+D ++E
Sbjct: 2 LQDKGLSESEEAFRAPGPALGEASAANAPEPALAAPGLSGAALGSPPGPGADVVAAAAAE 61
Query: 86 SLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVV 145
E +I++ L ELWK+FH+ GTEMIITKAGRRMFPS +VKV G++P +Y + ID+V
Sbjct: 62 QTIE-NIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIV 120
Query: 146 PVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNE 205
P D RY++ ++WMVAG + + R YVHPDSP +G WMRQ++SF ++KLTNN
Sbjct: 121 PADDHRYKFC--DNKWMVAGKAEP-AMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNH 177
Query: 206 MDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQ 265
+D GHIIL SMHKY+PR+H+++ D + T F ET F +VT+YQN
Sbjct: 178 LDPFGHIILNSMHKYQPRLHIVK----ADENNAFGSKNTAFCTHVFPETSFISVTSYQNH 233
Query: 266 QITKLKIERNPFAKGFR 282
+IT+LKIE NPFAKGFR
Sbjct: 234 KITQLKIENNPFAKGFR 250
>gi|197333868 T-box 2 [Homo sapiens]
Length = 712
Score = 209 bits (533), Expect = 4e-54
Identities = 116/253 (45%), Positives = 155/253 (61%), Gaps = 16/253 (6%)
Query: 89 EKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVD 148
E D ++ L+ ELW +FH +GTEM+ITK+GRRMFP +V+V GLD +Y + +D+V D
Sbjct: 102 EDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAAD 161
Query: 149 SKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDD 208
RY+ +H+S+WMVAG D + R Y+HPDSP +GE WM + ++F ++KLTNN D
Sbjct: 162 DCRYK--FHNSRWMVAGKADPE-MPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDK 218
Query: 209 KGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQIT 268
G IL SMHKY+PR H++ + I LP +T+ F ET+F VTAYQN +IT
Sbjct: 219 HGFTILNSMHKYQPRFHIVR------ANDILKLPYSTFRTYVFPETDFIAVTAYQNDKIT 272
Query: 269 KLKIERNPFAKGFRDTGRNRGVLDGLLETYPWRPSFTLDFK--TFGADTQSGS----SGS 322
+LKI+ NPFAKGFRDTG R L T P + K GA++ + S
Sbjct: 273 QLKIDNNPFAKGFRDTGNGRREKRKQL-TLPSLRLYEEHCKPERDGAESDASSCDPPPAR 331
Query: 323 SPVTSSGGAPSPL 335
P TS G APSPL
Sbjct: 332 EPPTSPGAAPSPL 344
>gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]
Length = 723
Score = 204 bits (520), Expect = 1e-52
Identities = 99/200 (49%), Positives = 134/200 (67%), Gaps = 9/200 (4%)
Query: 89 EKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVD 148
E D ++ L+ ELW +FH GTEM+ITK+GRRMFP +V+ GLD +Y + +D++ D
Sbjct: 100 EDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAAD 159
Query: 149 SKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDD 208
RY++ H+S+WMVAG D + R Y+HPDSP +GE WM ++++F ++KLTNN D
Sbjct: 160 DCRYKF--HNSRWMVAGKADPE-MPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDK 216
Query: 209 KGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQIT 268
G IL SMHKY+PR H++ + I LP +T+ F ETEF VTAYQN +IT
Sbjct: 217 HGFTILNSMHKYQPRFHIVR------ANDILKLPYSTFRTYLFPETEFIAVTAYQNDKIT 270
Query: 269 KLKIERNPFAKGFRDTGRNR 288
+LKI+ NPFAKGFRDTG R
Sbjct: 271 QLKIDNNPFAKGFRDTGNGR 290
>gi|18201896 T-box 5 isoform 2 [Homo sapiens]
Length = 349
Score = 200 bits (509), Expect = 2e-51
Identities = 123/301 (40%), Positives = 169/301 (56%), Gaps = 23/301 (7%)
Query: 57 PLEKQPKTEPSTSA-SSGCGSDSGYGNSSESLEEKD----IQMELQGSELWKRFHDIGTE 111
PLE K P S S G+ S +S ++ + I++ L ELW +FH++GTE
Sbjct: 14 PLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTE 73
Query: 112 MIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLC 171
MIITKAGRRMFPS +VKV GL+P +Y + +D+VP D RY++ ++W V G +
Sbjct: 74 MIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEP-A 130
Query: 172 IIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGS 231
+ R YVHPDSP +G WMRQ++SF ++KLTNN +D GHIIL SMHKY+PR+H+++
Sbjct: 131 MPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVK--- 187
Query: 232 SVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFR--DTGRNRG 289
D + T F ET F VT+YQN +IT+LKIE NPFAKGFR D
Sbjct: 188 -ADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHR 246
Query: 290 VLDGLLETYPWRPSFTLDFKT------FGADTQSGSSGS---SPVTSSGGAPSPLNSLLS 340
+ + YP P T+ K F +++++ S+ S S G P LL
Sbjct: 247 MSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGPSQDLLP 306
Query: 341 P 341
P
Sbjct: 307 P 307
>gi|18201892 T-box 5 isoform 1 [Homo sapiens]
Length = 518
Score = 200 bits (509), Expect = 2e-51
Identities = 123/301 (40%), Positives = 169/301 (56%), Gaps = 23/301 (7%)
Query: 57 PLEKQPKTEPSTSA-SSGCGSDSGYGNSSESLEEKD----IQMELQGSELWKRFHDIGTE 111
PLE K P S S G+ S +S ++ + I++ L ELW +FH++GTE
Sbjct: 14 PLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTE 73
Query: 112 MIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLC 171
MIITKAGRRMFPS +VKV GL+P +Y + +D+VP D RY++ ++W V G +
Sbjct: 74 MIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEP-A 130
Query: 172 IIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGS 231
+ R YVHPDSP +G WMRQ++SF ++KLTNN +D GHIIL SMHKY+PR+H+++
Sbjct: 131 MPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVK--- 187
Query: 232 SVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFR--DTGRNRG 289
D + T F ET F VT+YQN +IT+LKIE NPFAKGFR D
Sbjct: 188 -ADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHR 246
Query: 290 VLDGLLETYPWRPSFTLDFKT------FGADTQSGSSGS---SPVTSSGGAPSPLNSLLS 340
+ + YP P T+ K F +++++ S+ S S G P LL
Sbjct: 247 MSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGPSQDLLP 306
Query: 341 P 341
P
Sbjct: 307 P 307
>gi|31652232 T-box 5 isoform 1 [Homo sapiens]
Length = 518
Score = 200 bits (509), Expect = 2e-51
Identities = 123/301 (40%), Positives = 169/301 (56%), Gaps = 23/301 (7%)
Query: 57 PLEKQPKTEPSTSA-SSGCGSDSGYGNSSESLEEKD----IQMELQGSELWKRFHDIGTE 111
PLE K P S S G+ S +S ++ + I++ L ELW +FH++GTE
Sbjct: 14 PLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTE 73
Query: 112 MIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLC 171
MIITKAGRRMFPS +VKV GL+P +Y + +D+VP D RY++ ++W V G +
Sbjct: 74 MIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEP-A 130
Query: 172 IIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGS 231
+ R YVHPDSP +G WMRQ++SF ++KLTNN +D GHIIL SMHKY+PR+H+++
Sbjct: 131 MPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVK--- 187
Query: 232 SVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFR--DTGRNRG 289
D + T F ET F VT+YQN +IT+LKIE NPFAKGFR D
Sbjct: 188 -ADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHR 246
Query: 290 VLDGLLETYPWRPSFTLDFKT------FGADTQSGSSGS---SPVTSSGGAPSPLNSLLS 340
+ + YP P T+ K F +++++ S+ S S G P LL
Sbjct: 247 MSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGPSQDLLP 306
Query: 341 P 341
P
Sbjct: 307 P 307
>gi|18201894 T-box 5 isoform 3 [Homo sapiens]
Length = 468
Score = 198 bits (503), Expect = 1e-50
Identities = 113/261 (43%), Positives = 154/261 (59%), Gaps = 18/261 (6%)
Query: 92 IQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKR 151
I++ L ELW +FH++GTEMIITKAGRRMFPS +VKV GL+P +Y + +D+VP D R
Sbjct: 4 IKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHR 63
Query: 152 YRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGH 211
Y++ ++W V G + + R YVHPDSP +G WMRQ++SF ++KLTNN +D GH
Sbjct: 64 YKFA--DNKWSVTGKAEP-AMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120
Query: 212 IILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLK 271
IIL SMHKY+PR+H+++ D + T F ET F VT+YQN +IT+LK
Sbjct: 121 IILNSMHKYQPRLHIVK----ADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLK 176
Query: 272 IERNPFAKGFR--DTGRNRGVLDGLLETYPWRPSFTLDFKT------FGADTQSGSSGS- 322
IE NPFAKGFR D + + YP P T+ K F +++++ S+ S
Sbjct: 177 IENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSN 236
Query: 323 --SPVTSSGGAPSPLNSLLSP 341
S G P LL P
Sbjct: 237 LGSQYQCENGVSGPSQDLLPP 257
>gi|47419907 T-box 3 protein isoform 2 [Homo sapiens]
Length = 743
Score = 193 bits (490), Expect = 4e-49
Identities = 99/220 (45%), Positives = 134/220 (60%), Gaps = 29/220 (13%)
Query: 89 EKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVD 148
E D ++ L+ ELW +FH GTEM+ITK+GRRMFP +V+ GLD +Y + +D++ D
Sbjct: 100 EDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAAD 159
Query: 149 SKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDD 208
RY+ +H+S+WMVAG D + R Y+HPDSP +GE WM ++++F ++KLTNN D
Sbjct: 160 DCRYK--FHNSRWMVAGKADPE-MPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDK 216
Query: 209 KG--------------------HIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKT 248
G IL SMHKY+PR H++ + I LP +T
Sbjct: 217 HGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVR------ANDILKLPYSTFRT 270
Query: 249 FSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNR 288
+ F ETEF VTAYQN +IT+LKI+ NPFAKGFRDTG R
Sbjct: 271 YLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGR 310
>gi|122937388 MAX gene associated [Homo sapiens]
Length = 3114
Score = 186 bits (473), Expect = 3e-47
Identities = 90/196 (45%), Positives = 128/196 (65%), Gaps = 6/196 (3%)
Query: 92 IQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKR 151
I + L + +W F+ TEMI+TK GRRMFP R + GLD +Y + +D+ PVD+ R
Sbjct: 75 ITVTLDNNSMWNEFYHRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDISPVDNHR 134
Query: 152 YRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGH 211
Y++ + +W ++ R ++HP+SP +G WM Q +SF ++KLTNN +D +GH
Sbjct: 135 YKW---NGRWWEPSGKAEPHVLGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQEGH 191
Query: 212 IILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLK 271
IIL SMH+Y PR+H++ +V++ Q+ GV TF+F +TEF VTAYQN QIT+LK
Sbjct: 192 IILHSMHRYLPRLHLVPAEKAVEVIQLNG---PGVHTFTFPQTEFFAVTAYQNIQITQLK 248
Query: 272 IERNPFAKGFRDTGRN 287
I+ NPFAKGFRD G N
Sbjct: 249 IDYNPFAKGFRDDGLN 264
>gi|4827024 T-box 19 [Homo sapiens]
Length = 448
Score = 175 bits (444), Expect = 8e-44
Identities = 91/207 (43%), Positives = 131/207 (63%), Gaps = 20/207 (9%)
Query: 89 EKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVD 148
EK +Q+ L+ + LW+RF ++ EMI+TK GRRMFP +++ V GLDP Y + +D VP D
Sbjct: 38 EKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTD 97
Query: 149 SKRYRYVYHSSQWMVAGN---TDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNE 205
S R++YV + +W+ AG + H C+ Y+HPDSP G WM+ ISF ++KLT N+
Sbjct: 98 SHRWKYV--NGEWVPAGKPEVSSHSCV----YIHPDSPNFGAHWMKAPISFSKVKLT-NK 150
Query: 206 MDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQ 265
++ G I+L S+HKY+P+VH++ GS+ + V SF ET+F VTAYQN+
Sbjct: 151 LNGGGQIMLNSLHKYEPQVHIVRVGSAHRM----------VTNCSFPETQFIAVTAYQNE 200
Query: 266 QITKLKIERNPFAKGFRDTGRNRGVLD 292
+IT LKI+ NPFAK F D + D
Sbjct: 201 EITALKIKYNPFAKAFLDAKERNHLRD 227
>gi|22538470 eomesodermin [Homo sapiens]
Length = 686
Score = 174 bits (441), Expect = 2e-43
Identities = 95/223 (42%), Positives = 134/223 (60%), Gaps = 15/223 (6%)
Query: 66 PSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSV 125
P +A+ CG G G + L LW +FH TEMIITK GRRMFP +
Sbjct: 244 PGAAAAGSCGGLGGLGVPGSGFRA---HVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFL 300
Query: 126 RVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCS 185
+ GL+P Y+V ++VV D +R+ +W+ G D+ + YVHP+SP +
Sbjct: 301 SFNINGLNPTAHYNVFVEVVLADPNHWRF--QGGKWVTCGKADNNMQGNKMYVHPESPNT 358
Query: 186 GETWMRQIISFDRMKLTNNEMDDKGH---IILQSMHKYKPRVHVIE--QGSSVDLSQIQS 240
G WMRQ ISF ++KLTNN+ + + I+LQS+HKY+PR+H++E + DL++
Sbjct: 359 GSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNE--- 415
Query: 241 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRD 283
P++ +TF+F ET+F VTAYQN IT+LKI+ NPFAKGFRD
Sbjct: 416 -PSK-TQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRD 456
>gi|5730081 T-box, brain, 1 [Homo sapiens]
Length = 682
Score = 173 bits (439), Expect = 3e-43
Identities = 93/207 (44%), Positives = 127/207 (61%), Gaps = 8/207 (3%)
Query: 80 YGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYH 139
+ ++ L Q+ L LW +FH TEMIITK GRRMFP + + GLDP Y+
Sbjct: 192 FSSTQPGLVPGKAQVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHYN 251
Query: 140 VAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRM 199
+ +DV+ D +R + +W+ G D R Y+HPDSP +G WMRQ ISF ++
Sbjct: 252 IFVDVILADPNHWR--FQGGKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKL 309
Query: 200 KLTNNEMDDKGH---IILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEF 256
KLTNN+ + ++LQS+HKY+PR+HV+E D ++ S P V+TF+F ET+F
Sbjct: 310 KLTNNKGASNNNGQMVVLQSLHKYQPRLHVVEVNE--DGTEDTSQPGR-VQTFTFPETQF 366
Query: 257 TTVTAYQNQQITKLKIERNPFAKGFRD 283
VTAYQN IT+LKI+ NPFAKGFRD
Sbjct: 367 IAVTAYQNTDITQLKIDHNPFAKGFRD 393
>gi|7019549 T-box 21 [Homo sapiens]
Length = 535
Score = 169 bits (428), Expect = 6e-42
Identities = 105/273 (38%), Positives = 144/273 (52%), Gaps = 11/273 (4%)
Query: 14 ALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEKQPKTEPSTSASSG 73
ALV P R L +P+ G E + A G +P E +P G
Sbjct: 62 ALVPAPPSRFLGAYAYPPRPQAAGFPGAGESFPPPADAEGY-QPGEGYAAPDPRAGLYPG 120
Query: 74 CGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLD 133
D Y + +++ L LW +F+ TEMIITK GRRMFP + V GL+
Sbjct: 121 PRED--YALPAGLEVSGKLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLE 178
Query: 134 PGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQI 193
P Y + +DVV VD +R Y S +W+ G + R YVHPDSP +G WMRQ
Sbjct: 179 PTSHYRMFVDVVLVDQHHWR--YQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQE 236
Query: 194 ISFDRMKLTNNEMDDKG---HIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFS 250
+SF ++KLTNN+ I+LQS+HKY+PR+H++E + + T F+
Sbjct: 237 VSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTH---IFT 293
Query: 251 FKETEFTTVTAYQNQQITKLKIERNPFAKGFRD 283
F+ET+F VTAYQN +IT+LKI+ NPFAKGFR+
Sbjct: 294 FQETQFIAVTAYQNAEITQLKIDNNPFAKGFRE 326
>gi|4507339 transcription factor T [Homo sapiens]
Length = 435
Score = 167 bits (423), Expect = 2e-41
Identities = 120/357 (33%), Positives = 174/357 (48%), Gaps = 57/357 (15%)
Query: 81 GNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHV 140
G+ E+++++ L+ SELW RF ++ EMI+TK GRRMFP ++V V GLDP Y
Sbjct: 31 GSEKGDPTERELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSF 90
Query: 141 AIDVVPVDSKRYRYVYHSSQWMVAGNTD---HLCIIPRFYVHPDSPCSGETWMRQIISFD 197
+D V D+ R++YV + +W+ G + C+ Y+HPDSP G WM+ +SF
Sbjct: 91 LLDFVAADNHRWKYV--NGEWVPGGKPEPQAPSCV----YIHPDSPNFGAHWMKAPVSFS 144
Query: 198 RMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFT 257
++KLT N+++ G I+L S+HKY+PR+H++ G P + + F ET+F
Sbjct: 145 KVKLT-NKLNGGGQIMLNSLHKYEPRIHIVRVGG----------PQRMITSHCFPETQFI 193
Query: 258 TVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLE-----------TYPW-RPSFT 305
VTAYQN++IT LKI+ NPFAK F D + R ++E + W P +
Sbjct: 194 AVTAYQNEEITALKIKYNPFAKAFLD-AKERSDHKEMMEEPGDSQQPGYSQWGWLLPGTS 252
Query: 306 LDFKTFGADTQSGSSGSSPVT----------SSGGAP----------SPLNSLLSPLCFS 345
Q G + S P T S +P SP S SP C S
Sbjct: 253 TLCPPANPHPQFGGALSLPSTHSCDRYPTLRSHRSSPYPSPYAHRNNSPTYSDNSPACLS 312
Query: 346 PM-FHLPTSSLGMPCPEAYLP---NVNLPLCYKICPTNFWQQQPLVLPAPERLASSN 398
+ H SSLGMP + LP N + P P+ + V P + A SN
Sbjct: 313 MLQSHDNWSSLGMPAHPSMLPVSHNASPPTSSSQYPSLWSVSNGAVTPGSQAAAVSN 369
>gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]
Length = 1313
Score = 36.2 bits (82), Expect = 0.075
Identities = 41/119 (34%), Positives = 48/119 (40%), Gaps = 35/119 (29%)
Query: 352 TSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVP 411
TS LG P P + P LP P FW Q L LP P+R + Q L P VP
Sbjct: 920 TSVLGEPLPMPFTPT--LP------PGRFWHQYDL-LPGPQR-----TRQVLGPSRPGVP 965
Query: 412 MLSSLGVTNSKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHP 470
+S L NS + E S PN I LP+SI PEA+S P
Sbjct: 966 TMSLL---NSSRPTPEGSP------PNLP------------ILLPSSILPEAISLLLLP 1003
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 36.2 bits (82), Expect = 0.075
Identities = 30/121 (24%), Positives = 57/121 (47%), Gaps = 5/121 (4%)
Query: 1 MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEK 60
M +++ +A + +A + P+K+ Q + + EEEEE+ S +A K +P +
Sbjct: 441 MVATTKPKA-TAKAALSLPAKQAPQGSRDSSSDS--DSSSSEEEEEKTSKSAVKKKPQKV 497
Query: 61 QPKTEPS--TSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAG 118
PS SA G S +S +S EE++ +++ +GS + GT + + G
Sbjct: 498 AGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNG 557
Query: 119 R 119
+
Sbjct: 558 K 558
Score = 29.3 bits (64), Expect = 9.1
Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 6/78 (7%)
Query: 13 EALVGRPSKRKL--QDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEKQPKTEPSTSA 70
++L +P K+ + Q P+++ + E EEE++ + A S+ K P + + +
Sbjct: 302 KSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAES 361
Query: 71 SSGCGSDSGYGNSSESLE 88
S SDS +SSE E
Sbjct: 362 S----SDSSDSDSSEDDE 375
>gi|24430146 nucleoporin 153kDa [Homo sapiens]
Length = 1475
Score = 35.8 bits (81), Expect = 0.097
Identities = 61/204 (29%), Positives = 82/204 (40%), Gaps = 36/204 (17%)
Query: 311 FGADTQSGSSGSSPVTSSG-GAPSPLNSLLSPLCFSPMF---HLPTSSLGMPCPEAYLPN 366
FGA T S S+GSS V +G APS SP F PT + P
Sbjct: 1291 FGATTTSSSAGSSFVFGTGPSAPSA----------SPAFGANQTPTFGQSQGASQPNPPG 1340
Query: 367 V-NLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTNSKSGS 425
++ + PT PAP + +SS S P+ + P S+ G SG+
Sbjct: 1341 FGSISSSTALFPTG-------SQPAPPTFGTVSSS-SQPPVFGQQPSQSAFG-----SGT 1387
Query: 426 SEDSSDQYLQAPNSTNQMLYGLQSPGNIFL--PNSITPEALSCSFHPS-YDFYRYNFSMP 482
+ +SS + Q +ST + SP +F NS TP A S PS + +N S P
Sbjct: 1388 TPNSSSAF-QFGSSTTNFNFTNNSPSGVFTFGANSSTPAA---SAQPSGSGGFPFNQS-P 1442
Query: 483 SRLISGSNHLKVNDDSQVSFGEGK 506
+ GSN V S SF K
Sbjct: 1443 AAFTVGSNGKNVFSSSGTSFSGRK 1466
>gi|169167062 PREDICTED: hypothetical protein LOC285556 [Homo sapiens]
Length = 1826
Score = 35.4 bits (80), Expect = 0.13
Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 25/135 (18%)
Query: 314 DTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCY 373
D ++G P+TS A +P++ + PL SP + PT + +LP V
Sbjct: 1670 DPETGQYVDVPMTSQQQAVAPMSISVPPLALSPGAYGPTYMI----YPGFLPTV------ 1719
Query: 374 KICPTNFWQQQPLV-LPAPERLA---SSNSSQSLAPLMMEVPMLSSLGVTNSKSGSSEDS 429
PTN Q P+ P L+ + SS+ A E P + G + + S SS
Sbjct: 1720 --LPTNALQPTPIARAPRGSELSPMVAEPSSKEAAATFTEAPYFMASGQSPASSTSS--- 1774
Query: 430 SDQYLQAPNSTNQML 444
AP +T+Q+L
Sbjct: 1775 ------APAATSQLL 1783
>gi|113416182 PREDICTED: hypothetical protein LOC285556 [Homo sapiens]
Length = 1826
Score = 35.4 bits (80), Expect = 0.13
Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 25/135 (18%)
Query: 314 DTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCY 373
D ++G P+TS A +P++ + PL SP + PT + +LP V
Sbjct: 1670 DPETGQYVDVPMTSQQQAVAPMSISVPPLALSPGAYGPTYMI----YPGFLPTV------ 1719
Query: 374 KICPTNFWQQQPLV-LPAPERLA---SSNSSQSLAPLMMEVPMLSSLGVTNSKSGSSEDS 429
PTN Q P+ P L+ + SS+ A E P + G + + S SS
Sbjct: 1720 --LPTNALQPTPIARAPRGSELSPMVAEPSSKEAAATFTEAPYFMASGQSPASSTSS--- 1774
Query: 430 SDQYLQAPNSTNQML 444
AP +T+Q+L
Sbjct: 1775 ------APAATSQLL 1783
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,727,181
Number of Sequences: 37866
Number of extensions: 1108297
Number of successful extensions: 5221
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 106
Number of HSP's that attempted gapping in prelim test: 4911
Number of HSP's gapped (non-prelim): 340
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.