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Search of human proteins with 18254456
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18254456 testis-specific gene A2 [Homo sapiens]
(309 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18254456 testis-specific gene A2 [Homo sapiens] 657 0.0
gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens] 97 2e-20
gi|157502187 radial spoke head 10 homolog B [Homo sapiens] 97 2e-20
gi|13376267 MORN repeat containing 1 [Homo sapiens] 92 6e-19
gi|50355990 MORN repeat containing 3 [Homo sapiens] 89 6e-18
gi|40316935 alsin isoform 1 [Homo sapiens] 83 3e-16
gi|21704283 junctophilin 3 [Homo sapiens] 77 2e-14
gi|21704281 junctophilin 2 isoform 1 [Homo sapiens] 72 5e-13
gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens] 72 8e-13
gi|21735575 junctophilin 1 [Homo sapiens] 71 1e-12
gi|29893812 junctophilin 2 isoform 2 [Homo sapiens] 69 7e-12
gi|149999376 MORN repeat containing 4 [Homo sapiens] 66 3e-11
gi|30520314 MORN repeat containing 4 [Homo sapiens] 66 3e-11
gi|225690502 junctophilin 4 [Homo sapiens] 65 8e-11
gi|225690500 junctophilin 4 [Homo sapiens] 65 8e-11
gi|75750529 ankyrin repeat and MYND domain containing 1 isoform ... 65 8e-11
gi|75750531 ankyrin repeat and MYND domain containing 1 isoform ... 60 2e-09
gi|18139549 SET domain-containing protein 7 [Homo sapiens] 56 4e-08
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 55 8e-08
gi|224282170 MORN repeat containing 2 [Homo sapiens] 48 1e-05
gi|223278407 MORN repeat containing 5 [Homo sapiens] 47 2e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 40 0.003
gi|82830424 gon-4-like isoform a [Homo sapiens] 36 0.049
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 36 0.049
gi|58761530 polycomb group ring finger 6 isoform a [Homo sapiens] 36 0.049
gi|37655165 polycomb group ring finger 6 isoform b [Homo sapiens] 36 0.049
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 35 0.065
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear... 35 0.084
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear... 35 0.084
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 35 0.084
>gi|18254456 testis-specific gene A2 [Homo sapiens]
Length = 309
Score = 657 bits (1696), Expect = 0.0
Identities = 309/309 (100%), Positives = 309/309 (100%)
Query: 1 MSDLGSEELEEEGENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYK 60
MSDLGSEELEEEGENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYK
Sbjct: 1 MSDLGSEELEEEGENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYK 60
Query: 61 FKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAH 120
FKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAH
Sbjct: 61 FKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAH 120
Query: 121 QRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHRYQGKFLNKNPVGPGKYVFDVGC 180
QRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHRYQGKFLNKNPVGPGKYVFDVGC
Sbjct: 121 QRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHRYQGKFLNKNPVGPGKYVFDVGC 180
Query: 181 EQHGEYRLTDMERGEEEEEEELVTVVPKWKATQITELALWTPTLPKKPTSTDGPGQDAPG 240
EQHGEYRLTDMERGEEEEEEELVTVVPKWKATQITELALWTPTLPKKPTSTDGPGQDAPG
Sbjct: 181 EQHGEYRLTDMERGEEEEEEELVTVVPKWKATQITELALWTPTLPKKPTSTDGPGQDAPG 240
Query: 241 AESAGEPGEEAQALLEGFEGEMDMRPGDEDADVLREESREYDQEEFRYDMDEGNINSEEE 300
AESAGEPGEEAQALLEGFEGEMDMRPGDEDADVLREESREYDQEEFRYDMDEGNINSEEE
Sbjct: 241 AESAGEPGEEAQALLEGFEGEMDMRPGDEDADVLREESREYDQEEFRYDMDEGNINSEEE 300
Query: 301 ETRQSDLQD 309
ETRQSDLQD
Sbjct: 301 ETRQSDLQD 309
>gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens]
Length = 870
Score = 97.1 bits (240), Expect = 2e-20
Identities = 65/230 (28%), Positives = 88/230 (38%), Gaps = 61/230 (26%)
Query: 17 IGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKK 76
+ YEG + G G G A G TY G + G HGQG Y + +G +Y G++V+N
Sbjct: 83 VESYEGEKVR-GLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVP 141
Query: 77 HGQGTFIYPDGSRYEGE------------------------WANDLRHGHGVYYYINNDT 112
G + +PDGS YEGE W N RHG G YY T
Sbjct: 142 MNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGT 201
Query: 113 -------------------------YTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQE 147
Y G+W + RHG+G + T +Y G W G Q
Sbjct: 202 CWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQN 261
Query: 148 G-----------TAELIHLNHRYQGKFLNKNPVGPGKYVFDVGCEQHGEY 186
G + L + Y G+F+N G GK+ + G GE+
Sbjct: 262 GFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEW 311
Score = 83.6 bits (205), Expect = 2e-16
Identities = 48/158 (30%), Positives = 76/158 (48%), Gaps = 6/158 (3%)
Query: 42 DTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHG 101
++YEG G G+G F+ G Y G + HGQGT+I+ DG +YEG++ ++
Sbjct: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMN 143
Query: 102 HGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHR--- 158
HGVY + + Y GE R+G G + + Y+G W NG++ G I+ N
Sbjct: 144 HGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGS-IYYNQEGTC 202
Query: 159 -YQGKFLNKNPVGPGKYVFDVGCEQHGEYRLTDMERGE 195
Y+G ++ G G + G G++ +M GE
Sbjct: 203 WYEGDWVQNIKKGWGIRCYKSGNIYEGQWE-DNMRHGE 239
Score = 73.2 bits (178), Expect = 3e-13
Identities = 42/134 (31%), Positives = 64/134 (47%), Gaps = 12/134 (8%)
Query: 30 RHGRGRARLPNGDTYEGSYEFGKRHGQGIYKF-KNGARYIGEYVRNKKHGQGTFI----- 83
+ G G +G+ YEG +E RHG+G ++ Y G + R ++G GT
Sbjct: 213 KKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKR 272
Query: 84 -----YPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYV 138
YP + Y GE+ N RHG G +YY + Y GEW ++++HG G + + G Y
Sbjct: 273 IRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTF-KNGRVYE 331
Query: 139 GTWVNGQQEGTAEL 152
G + N G +L
Sbjct: 332 GAFSNDHIAGFPDL 345
Score = 67.8 bits (164), Expect = 1e-11
Identities = 39/111 (35%), Positives = 54/111 (48%), Gaps = 15/111 (13%)
Query: 18 GEYEGGRNEAGERHGRGRAR-LPNGDTYEGSYEFGKRHGQGI------------YKFKNG 64
G G+ E RHG GR R L + Y G +E G ++G G Y +N
Sbjct: 224 GNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRN- 282
Query: 65 ARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTG 115
YIGE+V +HG+G F Y G+ Y+GEW ++ +HG G + N Y G
Sbjct: 283 -EYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEG 332
Score = 60.1 bits (144), Expect = 2e-09
Identities = 32/85 (37%), Positives = 47/85 (55%), Gaps = 10/85 (11%)
Query: 23 GRNEAGERHGRGR----------ARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYV 72
GR E G ++G G ++ P + Y G + G RHG+G + + +GA Y GE+V
Sbjct: 253 GRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWV 312
Query: 73 RNKKHGQGTFIYPDGSRYEGEWAND 97
NKKHG G + +G YEG ++ND
Sbjct: 313 SNKKHGMGRLTFKNGRVYEGAFSND 337
>gi|157502187 radial spoke head 10 homolog B [Homo sapiens]
Length = 870
Score = 97.1 bits (240), Expect = 2e-20
Identities = 65/230 (28%), Positives = 88/230 (38%), Gaps = 61/230 (26%)
Query: 17 IGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKK 76
+ YEG + G G G A G TY G + G HGQG Y + +G +Y G++V+N
Sbjct: 83 VESYEGEKVR-GLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVP 141
Query: 77 HGQGTFIYPDGSRYEGE------------------------WANDLRHGHGVYYYINNDT 112
G + +PDGS YEGE W N RHG G YY T
Sbjct: 142 MNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGT 201
Query: 113 -------------------------YTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQE 147
Y G+W + RHG+G + T +Y G W G Q
Sbjct: 202 CWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQN 261
Query: 148 G-----------TAELIHLNHRYQGKFLNKNPVGPGKYVFDVGCEQHGEY 186
G + L + Y G+F+N G GK+ + G GE+
Sbjct: 262 GFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEW 311
Score = 83.6 bits (205), Expect = 2e-16
Identities = 48/158 (30%), Positives = 76/158 (48%), Gaps = 6/158 (3%)
Query: 42 DTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHG 101
++YEG G G+G F+ G Y G + HGQGT+I+ DG +YEG++ ++
Sbjct: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMN 143
Query: 102 HGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHR--- 158
HGVY + + Y GE R+G G + + Y+G W NG++ G I+ N
Sbjct: 144 HGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGS-IYYNQEGTC 202
Query: 159 -YQGKFLNKNPVGPGKYVFDVGCEQHGEYRLTDMERGE 195
Y+G ++ G G + G G++ +M GE
Sbjct: 203 WYEGDWVQNIKKGWGIRCYKSGNIYEGQWE-DNMRHGE 239
Score = 73.2 bits (178), Expect = 3e-13
Identities = 42/134 (31%), Positives = 64/134 (47%), Gaps = 12/134 (8%)
Query: 30 RHGRGRARLPNGDTYEGSYEFGKRHGQGIYKF-KNGARYIGEYVRNKKHGQGTFI----- 83
+ G G +G+ YEG +E RHG+G ++ Y G + R ++G GT
Sbjct: 213 KKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKR 272
Query: 84 -----YPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYV 138
YP + Y GE+ N RHG G +YY + Y GEW ++++HG G + + G Y
Sbjct: 273 IRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTF-KNGRVYE 331
Query: 139 GTWVNGQQEGTAEL 152
G + N G +L
Sbjct: 332 GAFSNDHIAGFPDL 345
Score = 67.8 bits (164), Expect = 1e-11
Identities = 39/111 (35%), Positives = 54/111 (48%), Gaps = 15/111 (13%)
Query: 18 GEYEGGRNEAGERHGRGRAR-LPNGDTYEGSYEFGKRHGQGI------------YKFKNG 64
G G+ E RHG GR R L + Y G +E G ++G G Y +N
Sbjct: 224 GNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRN- 282
Query: 65 ARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTG 115
YIGE+V +HG+G F Y G+ Y+GEW ++ +HG G + N Y G
Sbjct: 283 -EYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEG 332
Score = 60.1 bits (144), Expect = 2e-09
Identities = 32/85 (37%), Positives = 47/85 (55%), Gaps = 10/85 (11%)
Query: 23 GRNEAGERHGRGR----------ARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYV 72
GR E G ++G G ++ P + Y G + G RHG+G + + +GA Y GE+V
Sbjct: 253 GRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWV 312
Query: 73 RNKKHGQGTFIYPDGSRYEGEWAND 97
NKKHG G + +G YEG ++ND
Sbjct: 313 SNKKHGMGRLTFKNGRVYEGAFSND 337
>gi|13376267 MORN repeat containing 1 [Homo sapiens]
Length = 497
Score = 92.0 bits (227), Expect = 6e-19
Identities = 44/127 (34%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 18 GEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKH 77
G+ G+ GE G G G YEG G R G G ++G Y G + NK+H
Sbjct: 83 GDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRH 142
Query: 78 GQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKY 137
G G ++ +G +Y+G+W D R GHGV + TY G+W + G G+ + +G Y
Sbjct: 143 GPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHC-SGVTY 201
Query: 138 VGTWVNG 144
G W+NG
Sbjct: 202 YGLWING 208
Score = 89.7 bits (221), Expect = 3e-18
Identities = 52/166 (31%), Positives = 77/166 (46%), Gaps = 3/166 (1%)
Query: 18 GEYEGGRNEAGERHGRGRARLP-NGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKK 76
G Y G GE G GR +GDT+ G + G+ G G+ ++K G Y GE +
Sbjct: 59 GSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMR 118
Query: 77 HGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSK 136
G G + DG Y+G + ++ RHG G + N D Y G+W +R G G A+ GS
Sbjct: 119 EGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCAD-GST 177
Query: 137 YVGTWVNGQQEGTAELIHLNH-RYQGKFLNKNPVGPGKYVFDVGCE 181
Y G W + G + H + Y G ++N +P + +G E
Sbjct: 178 YKGQWHSDVFSGLGSMAHCSGVTYYGLWINGHPAEQATRIVILGPE 223
Score = 73.9 bits (180), Expect = 2e-13
Identities = 44/137 (32%), Positives = 73/137 (53%), Gaps = 4/137 (2%)
Query: 53 RHGQGIYKFKNGA-RYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYI-NN 110
R+G G+Y + N RY GE+ +KHG G ++ DGS YEG + + G G ++ +
Sbjct: 24 RNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSG 83
Query: 111 DTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHR-YQGKFLNKNPV 169
DT++G++ + G G Y + G Y G +G +EG L+ + + YQG F +
Sbjct: 84 DTFSGQFVLGEPQGYGVMEY-KAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRH 142
Query: 170 GPGKYVFDVGCEQHGEY 186
GPG+ +F G + G++
Sbjct: 143 GPGQMLFQNGDKYDGDW 159
Score = 72.8 bits (177), Expect = 4e-13
Identities = 44/144 (30%), Positives = 66/144 (45%), Gaps = 26/144 (18%)
Query: 30 RHGRGRARLPNGD-TYEGSYEFGKRHGQGIYKFKNGARY--------------------- 67
R+G G PN YEG ++ G++HG G FK+G+ Y
Sbjct: 24 RNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSG 83
Query: 68 ---IGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHG 124
G++V + G G Y G YEGE ++ +R GHG + Y G + ++RHG
Sbjct: 84 DTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHG 143
Query: 125 QGTYLYAETGSKYVGTWVNGQQEG 148
G L+ + G KY G WV +++G
Sbjct: 144 PGQMLF-QNGDKYDGDWVRDRRQG 166
>gi|50355990 MORN repeat containing 3 [Homo sapiens]
Length = 240
Score = 88.6 bits (218), Expect = 6e-18
Identities = 49/147 (33%), Positives = 69/147 (46%), Gaps = 8/147 (5%)
Query: 18 GEYEGGRNEAGERHGRG-RARLPNGDTYEGSYEFGKRHGQGIYKFKNGAR------YIGE 70
G+Y G E +HG+G + G YEG ++FGKR G G + Y G
Sbjct: 35 GDYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSGW 94
Query: 71 YVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLY 130
+ +KK G G + YEG+W R G G YY N D Y G+W + +G+G L
Sbjct: 95 WKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGM-LR 153
Query: 131 AETGSKYVGTWVNGQQEGTAELIHLNH 157
+ G++Y G W G + G HL+H
Sbjct: 154 LKNGNRYEGCWERGMKNGAGRFFHLDH 180
Score = 73.2 bits (178), Expect = 3e-13
Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 7/130 (5%)
Query: 20 YEGGRNEAGERHGRGRARLPNGDT------YEGSYEFGKRHGQGIYKFKNGARYIGEYVR 73
YEG + G+R G G LP+ T Y G ++ K+ G GI F Y G++
Sbjct: 62 YEGDW-KFGKRDGYGTLSLPDQQTGKCRRVYSGWWKGDKKSGYGIQFFGPKEYYEGDWCG 120
Query: 74 NKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAET 133
+++ G G Y +G YEG+W ND +G G+ N + Y G W ++G G + + +
Sbjct: 121 SQRSGWGRMYYSNGDIYEGQWENDKPNGEGMLRLKNGNRYEGCWERGMKNGAGRFFHLDH 180
Query: 134 GSKYVGTWVN 143
G + G WV+
Sbjct: 181 GQLFEGFWVD 190
Score = 63.2 bits (152), Expect = 3e-10
Identities = 33/81 (40%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Query: 19 EYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHG 78
EY G +R G GR NGD YEG +E K +G+G+ + KNG RY G + R K+G
Sbjct: 112 EYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGMLRLKNGNRYEGCWERGMKNG 171
Query: 79 QGTFIYPD-GSRYEGEWANDL 98
G F + D G +EG W +++
Sbjct: 172 AGRFFHLDHGQLFEGFWVDNM 192
Score = 62.0 bits (149), Expect = 6e-10
Identities = 37/118 (31%), Positives = 56/118 (47%), Gaps = 9/118 (7%)
Query: 63 NGARYIGEYVRNKKHGQGTFIY-PDGSRYEGEWANDLRHGHGVYYYINNDT------YTG 115
NG Y+GE+ N KHG+GT ++ G+ YEG+W R G+G + T Y+G
Sbjct: 34 NGDYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSG 93
Query: 116 EWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLN-HRYQGKFLNKNPVGPG 172
W ++ G G + Y G W Q+ G + + N Y+G++ N P G G
Sbjct: 94 WWKGDKKSGYGIQFFGPK-EYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEG 150
Score = 45.8 bits (107), Expect = 5e-05
Identities = 18/47 (38%), Positives = 29/47 (61%)
Query: 106 YYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAEL 152
Y +N D Y GEW + +HG+GT ++ + G+ Y G W G+++G L
Sbjct: 31 YAVNGDYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTL 77
Score = 37.0 bits (84), Expect = 0.022
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Query: 18 GEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQG-IYKFKNGARYIGEYVRN 74
G+ G+ E + +G G RL NG+ YEG +E G ++G G + +G + G +V N
Sbjct: 134 GDIYEGQWENDKPNGEGMLRLKNGNRYEGCWERGMKNGAGRFFHLDHGQLFEGFWVDN 191
>gi|40316935 alsin isoform 1 [Homo sapiens]
Length = 1657
Score = 83.2 bits (204), Expect = 3e-16
Identities = 49/175 (28%), Positives = 80/175 (45%), Gaps = 11/175 (6%)
Query: 23 GRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGA-----RYIGEYVRNKKH 77
GR +G+ HGRG + P+G Y G + G G G Y+ N A Y+G + K
Sbjct: 1051 GRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGKMC 1110
Query: 78 GQGTFIYPDGSRYEGEWANDLRHGHGV-----YYYINNDTYTGEWFAHQRHGQGTYLYAE 132
GQG + Y G +EG + +++RHGHG+ + + G+W ++ G G +
Sbjct: 1111 GQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFDDIT 1170
Query: 133 TGSKYVGTWVNGQQEGTAELI-HLNHRYQGKFLNKNPVGPGKYVFDVGCEQHGEY 186
G KY+G W + +G ++ Y+G F +G G + + GE+
Sbjct: 1171 RGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEF 1225
Score = 69.3 bits (168), Expect = 4e-12
Identities = 44/160 (27%), Positives = 71/160 (44%), Gaps = 11/160 (6%)
Query: 43 TYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGS-----RYEGEWAND 97
TY+G + GK HG+G+ K+ +G Y G + + G G + P+ + Y G W
Sbjct: 1048 TYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEG 1107
Query: 98 LRHGHGVYYYINNDTYTGEWFAHQRHGQGTY----LYAETGSKYVGTWVNGQQE--GTAE 151
G GVY Y + + + G + + RHG G L + + S ++G WV ++ G +
Sbjct: 1108 KMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFD 1167
Query: 152 LIHLNHRYQGKFLNKNPVGPGKYVFDVGCEQHGEYRLTDM 191
I +Y G + + G G V G G + L M
Sbjct: 1168 DITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKM 1207
Score = 60.1 bits (144), Expect = 2e-09
Identities = 43/138 (31%), Positives = 64/138 (46%), Gaps = 16/138 (11%)
Query: 65 ARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYIN-----NDTYTGEWFA 119
A Y G ++ K HG+G +PDG Y G + N L G+G Y N D Y G W
Sbjct: 1047 ATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKE 1106
Query: 120 HQRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHRYQGKFLNKNP-VGPGKYVFDV 178
+ GQG Y YA +G + G + + + G L GK + +P + G++V D
Sbjct: 1107 GKMCGQGVYSYA-SGEVFEGCFQDNMRHGHGLL------RSGKLTSSSPSMFIGQWVMD- 1158
Query: 179 GCEQHGEYRLTDMERGEE 196
++ G D+ RGE+
Sbjct: 1159 --KKAGYGVFDDITRGEK 1174
Score = 57.8 bits (138), Expect = 1e-08
Identities = 44/158 (27%), Positives = 68/158 (43%), Gaps = 13/158 (8%)
Query: 18 GEYEGGRNEAGERHGRGRARLPNG-----DTYEGSYEFGKRHGQGIYKFKNGARYIGEYV 72
G+ G G G G R+PN D Y G ++ GK GQG+Y + +G + G +
Sbjct: 1069 GKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGKMCGQGVYSYASGEVFEGCFQ 1128
Query: 73 RNKKHG-----QGTFIYPDGSRYEGEWANDLRHGHGVYYYI-NNDTYTGEWFAHQRHGQG 126
N +HG G S + G+W D + G+GV+ I + Y G W G G
Sbjct: 1129 DNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFDDITRGEKYMGMWQDDVCQGNG 1188
Query: 127 TYLYAETGSKYVGTWVNGQQEGTAELIHLNHR-YQGKF 163
+ + G Y G + + G L+ + Y+G+F
Sbjct: 1189 V-VVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEF 1225
Score = 41.2 bits (95), Expect = 0.001
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 5/85 (5%)
Query: 38 LPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWAND 97
+ G+ Y G ++ G G+ + G Y G + NK G G + D + YEGE+++D
Sbjct: 1169 ITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSDD 1228
Query: 98 -LRHGHGVYYYINND----TYTGEW 117
G G N D ++GEW
Sbjct: 1229 WTLSGKGTLTMPNGDYIEGYFSGEW 1253
Score = 34.3 bits (77), Expect = 0.14
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 6/59 (10%)
Query: 108 INNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHRYQGKFLNK 166
+ + TY G W + + HG+G + + G Y G + NG ++G E +R K +NK
Sbjct: 1044 LKDATYDGRWLSGKPHGRGVLKWPD-GKMYSGMFRNGLEDGYGE-----YRIPNKAMNK 1096
>gi|21704283 junctophilin 3 [Homo sapiens]
Length = 748
Score = 77.0 bits (188), Expect = 2e-14
Identities = 50/143 (34%), Positives = 67/143 (46%), Gaps = 8/143 (5%)
Query: 34 GRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHG---QGTFIYPDGSRY 90
GR +G +Y G +E GK HG G+ G + GEY + HG G + +P G+ Y
Sbjct: 5 GRFNFDDGGSYCGGWEDGKAHGHGVC---TGPKGQGEYTGSWSHGFEVLGVYTWPSGNTY 61
Query: 91 EGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEG-T 149
+G WA RHG G+ Y GEW + G A G+KY GTW NG Q+G
Sbjct: 62 QGTWAQGKRHGIGLESK-GKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYG 120
Query: 150 AELIHLNHRYQGKFLNKNPVGPG 172
E YQG+++ G G
Sbjct: 121 TETYSDGGTYQGQWVGGMRQGYG 143
Score = 67.4 bits (163), Expect = 2e-11
Identities = 43/138 (31%), Positives = 63/138 (45%), Gaps = 30/138 (21%)
Query: 15 NDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHG---QGIYKFKNGARYIGEY 71
+D G Y GG E G+ HG G P G +G Y HG G+Y + +G Y G +
Sbjct: 10 DDGGSYCGGW-EDGKAHGHGVCTGPKG---QGEYTGSWSHGFEVLGVYTWPSGNTYQGTW 65
Query: 72 VRNKKHG-----QGTFIYP------------------DGSRYEGEWANDLRHGHGVYYYI 108
+ K+HG +G ++Y +G++YEG W+N L+ G+G Y
Sbjct: 66 AQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYS 125
Query: 109 NNDTYTGEWFAHQRHGQG 126
+ TY G+W R G G
Sbjct: 126 DGGTYQGQWVGGMRQGYG 143
Score = 61.2 bits (147), Expect = 1e-09
Identities = 40/115 (34%), Positives = 54/115 (46%), Gaps = 25/115 (21%)
Query: 13 GENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQG-------IYK----- 60
G GEY G + E G P+G+TY+G++ GKRHG G +YK
Sbjct: 32 GPKGQGEYTGSWSHGFEV--LGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTH 89
Query: 61 -FK----------NGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGV 104
FK NGA+Y G + + G GT Y DG Y+G+W +R G+GV
Sbjct: 90 GFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGV 144
Score = 52.8 bits (125), Expect = 4e-07
Identities = 21/60 (35%), Positives = 38/60 (63%)
Query: 42 DTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHG 101
+TY G ++ KR G G+ + +G +Y GE+ N++HG G +PDG++ EG++ ++ G
Sbjct: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
Score = 45.8 bits (107), Expect = 5e-05
Identities = 19/51 (37%), Positives = 31/51 (60%)
Query: 67 YIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEW 117
Y+GE+ +K+ G G DG +YEGEWA++ RHG+G + + G++
Sbjct: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKY 338
Score = 43.5 bits (101), Expect = 2e-04
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 90 YEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTW 141
Y GEW ND R G GV + Y GEW +++RHG G + + G+K G +
Sbjct: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPD-GTKEEGKY 338
Score = 36.6 bits (83), Expect = 0.029
Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 5/61 (8%)
Query: 14 ENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVR 73
E +GE++ + R G G ++ +G YEG + +RHG G F +G + G+Y +
Sbjct: 286 ETYVGEWKNDK-----RSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQ 340
Query: 74 N 74
N
Sbjct: 341 N 341
Score = 30.8 bits (68), Expect = 1.6
Identities = 23/98 (23%), Positives = 42/98 (42%), Gaps = 1/98 (1%)
Query: 131 AETGSKYVGTWVNGQQEGTAELIHLNH-RYQGKFLNKNPVGPGKYVFDVGCEQHGEYRLT 189
A T YVG W N ++ G + +Y+G++ + G G F G ++ G+Y+
Sbjct: 282 ATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQN 341
Query: 190 DMERGEEEEEEELVTVVPKWKATQITELALWTPTLPKK 227
+ G+ + L + K + E A T+ K+
Sbjct: 342 ILVGGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQ 379
Score = 30.8 bits (68), Expect = 1.6
Identities = 14/38 (36%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Query: 111 DTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEG 148
+TY GEW +R G G ++ G KY G W + ++ G
Sbjct: 286 ETYVGEWKNDKRSGFGVSQRSD-GLKYEGEWASNRRHG 322
>gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]
Length = 696
Score = 72.4 bits (176), Expect = 5e-13
Identities = 47/136 (34%), Positives = 64/136 (47%), Gaps = 8/136 (5%)
Query: 34 GRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHG---QGTFIYPDGSRY 90
GR +G Y G +E GK HG G+ G + GEY + G G + +P G+ +
Sbjct: 4 GRFDFDDGGAYCGGWEGGKAHGHGLC---TGPKGQGEYSGSWNFGFEVAGVYTWPSGNTF 60
Query: 91 EGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEG-T 149
EG W+ RHG G+ Y GEW + G + +G+KY GTW NG Q+G
Sbjct: 61 EGYWSQGKRHGLGIETK-GRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYG 119
Query: 150 AELIHLNHRYQGKFLN 165
E YQG+F N
Sbjct: 120 TETYADGGTYQGQFTN 135
Score = 65.9 bits (159), Expect = 4e-11
Identities = 43/115 (37%), Positives = 56/115 (48%), Gaps = 4/115 (3%)
Query: 13 GENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYV 72
G GEY G N E G P+G+T+EG + GKRHG GI + K Y GE+
Sbjct: 31 GPKGQGEYSGSWNFGFEV--AGVYTWPSGNTFEGYWSQGKRHGLGI-ETKGRWLYKGEWT 87
Query: 73 RNKKHGQGTF-IYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQG 126
K G G++YEG W N L+ G+G Y + TY G++ RHG G
Sbjct: 88 HGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYG 142
Score = 53.5 bits (127), Expect = 2e-07
Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Query: 2 SDLGSEELEEEGENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKF 61
SDL S + +GE G +EA A +TY G ++ KR G G+ +
Sbjct: 251 SDLSSGASDAASTASLGEAAEGADEAAPFEADIDATTT--ETYMGEWKNDKRSGFGVSER 308
Query: 62 KNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDL 98
+G RY GE++ N +HG G PDG R EG++ +++
Sbjct: 309 SSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNV 345
Score = 43.9 bits (102), Expect = 2e-04
Identities = 18/37 (48%), Positives = 25/37 (67%)
Query: 67 YIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHG 103
Y+GE+ +K+ G G G RYEGEW ++LRHG+G
Sbjct: 291 YMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYG 327
Score = 40.0 bits (92), Expect = 0.003
Identities = 18/37 (48%), Positives = 20/37 (54%)
Query: 90 YEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQG 126
Y GEW ND R G GV + Y GEW + RHG G
Sbjct: 291 YMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYG 327
Score = 30.8 bits (68), Expect = 1.6
Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
Query: 111 DTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEG-TAELIHLNHRYQGKF 163
+TY GEW +R G G +G +Y G W++ + G + HR +GK+
Sbjct: 289 ETYMGEWKNDKRSGFGV-SERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKY 341
>gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]
Length = 953
Score = 71.6 bits (174), Expect = 8e-13
Identities = 47/163 (28%), Positives = 66/163 (40%), Gaps = 33/163 (20%)
Query: 43 TYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSR------------- 89
TYEG + G+ HG+G K+ +G ++G + + +HG G + P S
Sbjct: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREG 416
Query: 90 ---------------YEGEWANDLRHGHGVY----YYINNDTYTGEWFAHQRHGQGTYLY 130
Y+G + LRHG GV YTG W QR G G
Sbjct: 417 SMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEED 476
Query: 131 AETGSKYVGTWVNGQQEGTAELI-HLNHRYQGKFLNKNPVGPG 172
+ G +Y+G W GQ+ G ++ YQG F VGPG
Sbjct: 477 GDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPG 519
Score = 49.7 bits (117), Expect = 3e-06
Identities = 35/115 (30%), Positives = 51/115 (44%), Gaps = 2/115 (1%)
Query: 23 GRNEAGERHGRG-RARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGT 81
G E G+R G G G+ Y G ++ G+RHG G+ + G Y G + +K G G
Sbjct: 461 GHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGI 520
Query: 82 FIYPDGSRYEGEWANDLR-HGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGS 135
+ D S YEG + DL G G + N T G + + G T +T +
Sbjct: 521 LLSEDDSLYEGTFTRDLTLMGKGKVTFPNGFTLEGSFGSGAGRGLHTQGVLDTAA 575
Score = 47.0 bits (110), Expect = 2e-05
Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 9 LEEEGENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYI 68
+EE+G D GE G +AG+RHG G G Y+G+++ K G GI ++ + Y
Sbjct: 473 IEEDG--DRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYE 530
Query: 69 GEYVRN-KKHGQGTFIYPDGSRYEGEWANDLRHG 101
G + R+ G+G +P+G EG + + G
Sbjct: 531 GTFTRDLTLMGKGKVTFPNGFTLEGSFGSGAGRG 564
>gi|21735575 junctophilin 1 [Homo sapiens]
Length = 661
Score = 71.2 bits (173), Expect = 1e-12
Identities = 45/118 (38%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 34 GRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHG---QGTFIYPDGSRY 90
GR +G TY G +E GK HG GI G + GEY + HG G + +P G+ Y
Sbjct: 4 GRFDFDDGGTYCGGWEEGKAHGHGIC---TGPKGQGEYSGSWSHGFEVVGGYTWPSGNTY 60
Query: 91 EGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEG 148
+G WA RHG GV Y GEW + G T ++Y GTW NG Q+G
Sbjct: 61 QGYWAQGKRHGLGVETK-GKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDG 117
Score = 68.6 bits (166), Expect = 7e-12
Identities = 44/117 (37%), Positives = 59/117 (50%), Gaps = 8/117 (6%)
Query: 13 GENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYV 72
G GEY G + E G P+G+TY+G + GKRHG G+ + K Y GE+
Sbjct: 31 GPKGQGEYSGSWSHGFEVVGG--YTWPSGNTYQGYWAQGKRHGLGV-ETKGKWMYRGEWS 87
Query: 73 RNKKHGQG---TFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQG 126
K G + P +RYEG W+N L+ G+GV Y + TY G+W RHG G
Sbjct: 88 HGFKGRYGVRQSLCTP--ARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYG 142
Score = 60.8 bits (146), Expect = 1e-09
Identities = 24/57 (42%), Positives = 40/57 (70%)
Query: 42 DTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDL 98
+TY G ++ KR+G G+ + NG +Y GE+ NK+HG G ++PDGS+ EG++ N++
Sbjct: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
Score = 48.1 bits (113), Expect = 1e-05
Identities = 24/54 (44%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 90 YEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVN 143
Y GEW ND R+G GV N Y GEW ++RHG G ++ + GSK G + N
Sbjct: 281 YMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPD-GSKEEGKYKN 333
Score = 46.6 bits (109), Expect = 3e-05
Identities = 19/51 (37%), Positives = 32/51 (62%)
Query: 67 YIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEW 117
Y+GE+ +K++G G +G +YEGEWAN+ RHG+G + + G++
Sbjct: 281 YMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKY 331
Score = 45.1 bits (105), Expect = 8e-05
Identities = 36/134 (26%), Positives = 51/134 (38%), Gaps = 31/134 (23%)
Query: 80 GTFIYPDGSRYEGEWANDLRHGHGV-----------------------YYYINNDTYTGE 116
G F + DG Y G W HGHG+ Y + + +TY G
Sbjct: 4 GRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGY 63
Query: 117 WFAHQRHGQGTYLYAETGSK--YVGTWVNG--QQEGTAELIHLNHRYQGKFLNKNPVGPG 172
W +RHG G ET K Y G W +G + G + + RY+G + N G G
Sbjct: 64 WAQGKRHGLG----VETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYG 119
Query: 173 KYVFDVGCEQHGEY 186
+ G G++
Sbjct: 120 VETYGDGGTYQGQW 133
Score = 38.5 bits (88), Expect = 0.008
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 5/61 (8%)
Query: 14 ENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVR 73
E +GE++ + R+G G + NG YEG + KRHG G F +G++ G+Y
Sbjct: 279 ETYMGEWKNDK-----RNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKN 333
Query: 74 N 74
N
Sbjct: 334 N 334
Score = 35.0 bits (79), Expect = 0.084
Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
Query: 131 AETGSKYVGTWVNGQQEGTAELIHLNH-RYQGKFLNKNPVGPGKYVFDVGCEQHGEYRLT 189
A T Y+G W N ++ G N +Y+G++ N G G VF G ++ G+Y+
Sbjct: 275 ATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNN 334
Query: 190 DMERG 194
+ RG
Sbjct: 335 ILVRG 339
>gi|29893812 junctophilin 2 isoform 2 [Homo sapiens]
Length = 129
Score = 68.6 bits (166), Expect = 7e-12
Identities = 41/118 (34%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 34 GRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHG---QGTFIYPDGSRY 90
GR +G Y G +E GK HG G+ G + GEY + G G + +P G+ +
Sbjct: 4 GRFDFDDGGAYCGGWEGGKAHGHGLC---TGPKGQGEYSGSWNFGFEVAGVYTWPSGNTF 60
Query: 91 EGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEG 148
EG W+ RHG G+ Y GEW + G + +G+KY GTW NG Q+G
Sbjct: 61 EGYWSQGKRHGLGIETK-GRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDG 117
Score = 57.0 bits (136), Expect = 2e-08
Identities = 41/123 (33%), Positives = 60/123 (48%), Gaps = 7/123 (5%)
Query: 15 NDIGEYEGGRNEAGERHGRGRARLPNGD-TYEGSYEFGKRHGQGIYKFKNGARYIGEYVR 73
+D G Y GG E G+ HG G P G Y GS+ FG G+Y + +G + G + +
Sbjct: 9 DDGGAYCGGW-EGGKAHGHGLCTGPKGQGEYSGSWNFGFEVA-GVYTWPSGNTFEGYWSQ 66
Query: 74 NKKHGQGTFIYPDGS-RYEGEWANDLRHGHGVYYYINNDT-YTGEWFAHQRHGQGTYLYA 131
K+HG G I G Y+GEW + + +G+ ++ Y G W + G GT YA
Sbjct: 67 GKRHGLG--IETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYA 124
Query: 132 ETG 134
+ G
Sbjct: 125 DGG 127
Score = 51.6 bits (122), Expect = 9e-07
Identities = 36/96 (37%), Positives = 46/96 (47%), Gaps = 4/96 (4%)
Query: 13 GENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYV 72
G GEY G N E G P+G+T+EG + GKRHG GI + K Y GE+
Sbjct: 31 GPKGQGEYSGSWNFGFEV--AGVYTWPSGNTFEGYWSQGKRHGLGI-ETKGRWLYKGEWT 87
Query: 73 RNKKHGQGTF-IYPDGSRYEGEWANDLRHGHGVYYY 107
K G G++YEG W N L+ G+G Y
Sbjct: 88 HGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETY 123
>gi|149999376 MORN repeat containing 4 [Homo sapiens]
Length = 146
Score = 66.2 bits (160), Expect = 3e-11
Identities = 31/85 (36%), Positives = 48/85 (56%)
Query: 33 RGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEG 92
+G +G+ Y G ++ G+RHG G F +G Y+G + +G G + DGSRYEG
Sbjct: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEG 64
Query: 93 EWANDLRHGHGVYYYINNDTYTGEW 117
E+A +G GV+ +N T+ GE+
Sbjct: 65 EFAQGKFNGVGVFIRYDNMTFEGEF 89
Score = 66.2 bits (160), Expect = 3e-11
Identities = 34/87 (39%), Positives = 48/87 (55%)
Query: 18 GEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKH 77
GE G + G RHG G+ +G TY G +E G +G G+ F +G+RY GE+ + K +
Sbjct: 13 GEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFN 72
Query: 78 GQGTFIYPDGSRYEGEWANDLRHGHGV 104
G G FI D +EGE+ N G G+
Sbjct: 73 GVGVFIRYDNMTFEGEFKNGRVDGFGL 99
Score = 54.7 bits (130), Expect = 1e-07
Identities = 26/93 (27%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
Query: 56 QGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTG 115
+G + + +G Y GE+ ++HG G ++ DG Y G + N L +G GV + + Y G
Sbjct: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEG 64
Query: 116 EWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEG 148
E+ + +G G ++ + + G + NG+ +G
Sbjct: 65 EFAQGKFNGVGVFIRYD-NMTFEGEFKNGRVDG 96
>gi|30520314 MORN repeat containing 4 [Homo sapiens]
Length = 146
Score = 66.2 bits (160), Expect = 3e-11
Identities = 31/85 (36%), Positives = 48/85 (56%)
Query: 33 RGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEG 92
+G +G+ Y G ++ G+RHG G F +G Y+G + +G G + DGSRYEG
Sbjct: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEG 64
Query: 93 EWANDLRHGHGVYYYINNDTYTGEW 117
E+A +G GV+ +N T+ GE+
Sbjct: 65 EFAQGKFNGVGVFIRYDNMTFEGEF 89
Score = 66.2 bits (160), Expect = 3e-11
Identities = 34/87 (39%), Positives = 48/87 (55%)
Query: 18 GEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKH 77
GE G + G RHG G+ +G TY G +E G +G G+ F +G+RY GE+ + K +
Sbjct: 13 GEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFN 72
Query: 78 GQGTFIYPDGSRYEGEWANDLRHGHGV 104
G G FI D +EGE+ N G G+
Sbjct: 73 GVGVFIRYDNMTFEGEFKNGRVDGFGL 99
Score = 54.7 bits (130), Expect = 1e-07
Identities = 26/93 (27%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
Query: 56 QGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTG 115
+G + + +G Y GE+ ++HG G ++ DG Y G + N L +G GV + + Y G
Sbjct: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEG 64
Query: 116 EWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEG 148
E+ + +G G ++ + + G + NG+ +G
Sbjct: 65 EFAQGKFNGVGVFIRYD-NMTFEGEFKNGRVDG 96
>gi|225690502 junctophilin 4 [Homo sapiens]
Length = 628
Score = 65.1 bits (157), Expect = 8e-11
Identities = 32/88 (36%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Query: 39 PNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDL 98
P G +Y+G ++ GKR G G+ + K+ Y GE++ K G + G RY G W +
Sbjct: 56 PGGHSYQGHWQQGKREGLGVER-KSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGF 114
Query: 99 RHGHGVYYYINNDTYTGEWFAHQRHGQG 126
+ G+G Y + TY G+W A +RHG G
Sbjct: 115 QDGYGTETYSDGGTYQGQWQAGKRHGYG 142
Score = 59.7 bits (143), Expect = 3e-09
Identities = 43/134 (32%), Positives = 59/134 (44%), Gaps = 9/134 (6%)
Query: 34 GRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHG---QGTFIYPDGSRY 90
G+ +G Y G +E G+ HG G+ G GEY HG G F P G Y
Sbjct: 5 GKFDFDDGGCYVGGWEAGRAHGYGVC---TGPGAQGEYSGCWAHGFESLGVFTGPGGHSY 61
Query: 91 EGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEG-T 149
+G W R G GV + TY GEW + G + + +G +Y G W +G Q+G
Sbjct: 62 QGHWQQGKREGLGVERK-SRWTYRGEWLGGLKGRSGVW-ESVSGLRYAGLWKDGFQDGYG 119
Query: 150 AELIHLNHRYQGKF 163
E YQG++
Sbjct: 120 TETYSDGGTYQGQW 133
Score = 56.6 bits (135), Expect = 3e-08
Identities = 45/139 (32%), Positives = 61/139 (43%), Gaps = 13/139 (9%)
Query: 15 NDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHG---QGIYKFKNGARYIGEY 71
+D G Y GG EAG HG G P +G Y HG G++ G Y G +
Sbjct: 10 DDGGCYVGGW-EAGRAHGYGVCTGPGA---QGEYSGCWAHGFESLGVFTGPGGHSYQGHW 65
Query: 72 VRNKKHGQGTFIYPDGSR--YEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYL 129
+ K+ G G SR Y GEW L+ GV+ ++ Y G W + G GT
Sbjct: 66 QQGKREGLGV---ERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTET 122
Query: 130 YAETGSKYVGTWVNGQQEG 148
Y++ G Y G W G++ G
Sbjct: 123 YSD-GGTYQGQWQAGKRHG 140
Score = 56.2 bits (134), Expect = 4e-08
Identities = 37/106 (34%), Positives = 53/106 (50%), Gaps = 6/106 (5%)
Query: 2 SDLGSEE--LEEEGENDIGEYEGGRNEAGERHGRGRARLPNG---DTYEGSYEFGKRHGQ 56
S LGS+ L E +++G +EA L G + Y G + +R G
Sbjct: 235 SSLGSKRGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGF 294
Query: 57 GIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEW-ANDLRHG 101
G+ + NG RY GE++ N++HG G PDGSR EG++ N L HG
Sbjct: 295 GVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHG 340
Score = 54.7 bits (130), Expect = 1e-07
Identities = 29/82 (35%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Query: 23 GRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTF 82
G + G+R G G R TY G + G + G+++ +G RY G + + G GT
Sbjct: 63 GHWQQGKREGLGVERKSRW-TYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTE 121
Query: 83 IYPDGSRYEGEWANDLRHGHGV 104
Y DG Y+G+W RHG+GV
Sbjct: 122 TYSDGGTYQGQWQAGKRHGYGV 143
Score = 41.6 bits (96), Expect = 0.001
Identities = 18/37 (48%), Positives = 20/37 (54%)
Query: 90 YEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQG 126
Y GEW D R G GV N Y GEW ++RHG G
Sbjct: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYG 318
Score = 38.9 bits (89), Expect = 0.006
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 67 YIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHG 103
Y GE+ +++ G G +G RYEGEW + RHG+G
Sbjct: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYG 318
Score = 38.5 bits (88), Expect = 0.008
Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 3/86 (3%)
Query: 80 GTFIYPDGSRYEGEWANDLRHGHGVYYYIN-NDTYTGEWFAHQRHGQGTYLYAETGSKYV 138
G F + DG Y G W HG+GV Y+G W AH G + G Y
Sbjct: 5 GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCW-AHGFESLGVFT-GPGGHSYQ 62
Query: 139 GTWVNGQQEGTAELIHLNHRYQGKFL 164
G W G++EG Y+G++L
Sbjct: 63 GHWQQGKREGLGVERKSRWTYRGEWL 88
Score = 30.8 bits (68), Expect = 1.6
Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 2/64 (3%)
Query: 111 DTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLN-HRYQGKFLNKNPV 169
+ Y GEW A +R G G G +Y G W+ ++ G + R +GK+ V
Sbjct: 280 EVYAGEWRADRRSGFGV-SQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLV 338
Query: 170 GPGK 173
G+
Sbjct: 339 HGGR 342
Score = 30.0 bits (66), Expect = 2.7
Identities = 18/70 (25%), Positives = 26/70 (37%)
Query: 103 GVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHRYQGK 162
G + + + Y G W A + HG G +Y G W +G + H YQG
Sbjct: 5 GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQGH 64
Query: 163 FLNKNPVGPG 172
+ G G
Sbjct: 65 WQQGKREGLG 74
>gi|225690500 junctophilin 4 [Homo sapiens]
Length = 628
Score = 65.1 bits (157), Expect = 8e-11
Identities = 32/88 (36%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Query: 39 PNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDL 98
P G +Y+G ++ GKR G G+ + K+ Y GE++ K G + G RY G W +
Sbjct: 56 PGGHSYQGHWQQGKREGLGVER-KSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGF 114
Query: 99 RHGHGVYYYINNDTYTGEWFAHQRHGQG 126
+ G+G Y + TY G+W A +RHG G
Sbjct: 115 QDGYGTETYSDGGTYQGQWQAGKRHGYG 142
Score = 59.7 bits (143), Expect = 3e-09
Identities = 43/134 (32%), Positives = 59/134 (44%), Gaps = 9/134 (6%)
Query: 34 GRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHG---QGTFIYPDGSRY 90
G+ +G Y G +E G+ HG G+ G GEY HG G F P G Y
Sbjct: 5 GKFDFDDGGCYVGGWEAGRAHGYGVC---TGPGAQGEYSGCWAHGFESLGVFTGPGGHSY 61
Query: 91 EGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEG-T 149
+G W R G GV + TY GEW + G + + +G +Y G W +G Q+G
Sbjct: 62 QGHWQQGKREGLGVERK-SRWTYRGEWLGGLKGRSGVW-ESVSGLRYAGLWKDGFQDGYG 119
Query: 150 AELIHLNHRYQGKF 163
E YQG++
Sbjct: 120 TETYSDGGTYQGQW 133
Score = 56.6 bits (135), Expect = 3e-08
Identities = 45/139 (32%), Positives = 61/139 (43%), Gaps = 13/139 (9%)
Query: 15 NDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHG---QGIYKFKNGARYIGEY 71
+D G Y GG EAG HG G P +G Y HG G++ G Y G +
Sbjct: 10 DDGGCYVGGW-EAGRAHGYGVCTGPGA---QGEYSGCWAHGFESLGVFTGPGGHSYQGHW 65
Query: 72 VRNKKHGQGTFIYPDGSR--YEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYL 129
+ K+ G G SR Y GEW L+ GV+ ++ Y G W + G GT
Sbjct: 66 QQGKREGLGV---ERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTET 122
Query: 130 YAETGSKYVGTWVNGQQEG 148
Y++ G Y G W G++ G
Sbjct: 123 YSD-GGTYQGQWQAGKRHG 140
Score = 56.2 bits (134), Expect = 4e-08
Identities = 37/106 (34%), Positives = 53/106 (50%), Gaps = 6/106 (5%)
Query: 2 SDLGSEE--LEEEGENDIGEYEGGRNEAGERHGRGRARLPNG---DTYEGSYEFGKRHGQ 56
S LGS+ L E +++G +EA L G + Y G + +R G
Sbjct: 235 SSLGSKRGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGF 294
Query: 57 GIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEW-ANDLRHG 101
G+ + NG RY GE++ N++HG G PDGSR EG++ N L HG
Sbjct: 295 GVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHG 340
Score = 54.7 bits (130), Expect = 1e-07
Identities = 29/82 (35%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Query: 23 GRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTF 82
G + G+R G G R TY G + G + G+++ +G RY G + + G GT
Sbjct: 63 GHWQQGKREGLGVERKSRW-TYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTE 121
Query: 83 IYPDGSRYEGEWANDLRHGHGV 104
Y DG Y+G+W RHG+GV
Sbjct: 122 TYSDGGTYQGQWQAGKRHGYGV 143
Score = 41.6 bits (96), Expect = 0.001
Identities = 18/37 (48%), Positives = 20/37 (54%)
Query: 90 YEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQG 126
Y GEW D R G GV N Y GEW ++RHG G
Sbjct: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYG 318
Score = 38.9 bits (89), Expect = 0.006
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 67 YIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHG 103
Y GE+ +++ G G +G RYEGEW + RHG+G
Sbjct: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYG 318
Score = 38.5 bits (88), Expect = 0.008
Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 3/86 (3%)
Query: 80 GTFIYPDGSRYEGEWANDLRHGHGVYYYIN-NDTYTGEWFAHQRHGQGTYLYAETGSKYV 138
G F + DG Y G W HG+GV Y+G W AH G + G Y
Sbjct: 5 GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCW-AHGFESLGVFT-GPGGHSYQ 62
Query: 139 GTWVNGQQEGTAELIHLNHRYQGKFL 164
G W G++EG Y+G++L
Sbjct: 63 GHWQQGKREGLGVERKSRWTYRGEWL 88
Score = 30.8 bits (68), Expect = 1.6
Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 2/64 (3%)
Query: 111 DTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLN-HRYQGKFLNKNPV 169
+ Y GEW A +R G G G +Y G W+ ++ G + R +GK+ V
Sbjct: 280 EVYAGEWRADRRSGFGV-SQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLV 338
Query: 170 GPGK 173
G+
Sbjct: 339 HGGR 342
Score = 30.0 bits (66), Expect = 2.7
Identities = 18/70 (25%), Positives = 26/70 (37%)
Query: 103 GVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHRYQGK 162
G + + + Y G W A + HG G +Y G W +G + H YQG
Sbjct: 5 GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQGH 64
Query: 163 FLNKNPVGPG 172
+ G G
Sbjct: 65 WQQGKREGLG 74
>gi|75750529 ankyrin repeat and MYND domain containing 1 isoform 1
[Homo sapiens]
Length = 941
Score = 65.1 bits (157), Expect = 8e-11
Identities = 34/102 (33%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Query: 44 YEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHG 103
Y+G + + G G + + G Y G++ R+ HG GT+++PDGS + G + R G+G
Sbjct: 2 YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYG 61
Query: 104 VYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQ 145
Y+ + G + A QR G G Y + GS+ VG W Q
Sbjct: 62 T-MYMKTRLFQGLYKADQRFGPGVETYPD-GSQDVGLWFREQ 101
Score = 53.1 bits (126), Expect = 3e-07
Identities = 25/95 (26%), Positives = 49/95 (51%), Gaps = 1/95 (1%)
Query: 90 YEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGT 149
Y+GE+ +++ G+G + + ++Y G+++ HG GTY++ + GS + GT+ +EG
Sbjct: 2 YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPD-GSSFTGTFYLSHREGY 60
Query: 150 AELIHLNHRYQGKFLNKNPVGPGKYVFDVGCEQHG 184
+ +QG + GPG + G + G
Sbjct: 61 GTMYMKTRLFQGLYKADQRFGPGVETYPDGSQDVG 95
Score = 51.6 bits (122), Expect = 9e-07
Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
Query: 32 GRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYE 91
G G+ P G++Y G + HG G Y + +G+ + G + + + G GT +Y ++
Sbjct: 13 GYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYGT-MYMKTRLFQ 71
Query: 92 GEWANDLRHGHGVYYYINNDTYTGEWFAHQ 121
G + D R G GV Y + G WF Q
Sbjct: 72 GLYKADQRFGPGVETYPDGSQDVGLWFREQ 101
Score = 42.0 bits (97), Expect = 7e-04
Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Query: 18 GEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKH 77
GE G+ HG G P+G ++ G++ R G G K + G Y +++
Sbjct: 22 GESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYGTMYMKT-RLFQGLYKADQRF 80
Query: 78 GQGTFIYPDGSRYEGEW 94
G G YPDGS+ G W
Sbjct: 81 GPGVETYPDGSQDVGLW 97
>gi|75750531 ankyrin repeat and MYND domain containing 1 isoform 2
[Homo sapiens]
Length = 717
Score = 60.5 bits (145), Expect = 2e-09
Identities = 28/78 (35%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 56 QGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTG 115
QG+ ++++G Y GE+ N K G G F +P G Y G++ D HG G Y + + ++TG
Sbjct: 80 QGVQEWQDGCMYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTG 139
Query: 116 EWFAHQRHGQGTYLYAET 133
++ R G GT +Y +T
Sbjct: 140 TFYLSHREGYGT-MYMKT 156
Score = 53.1 bits (126), Expect = 3e-07
Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 2/100 (2%)
Query: 7 EELEEEGENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGAR 66
E+ EEE E + + E+ + +G +G Y+G + + G G + + G
Sbjct: 56 EKEEEEAEGPLRAQD--LRESYIQLVQGVQEWQDGCMYQGEFGLNMKLGYGKFSWPTGES 113
Query: 67 YIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYY 106
Y G++ R+ HG GT+++PDGS + G + R G+G Y
Sbjct: 114 YHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYGTMY 153
Score = 50.4 bits (119), Expect = 2e-06
Identities = 22/70 (31%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
Query: 79 QGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYV 138
QG + DG Y+GE+ +++ G+G + + ++Y G+++ HG GTY++ + GS +
Sbjct: 80 QGVQEWQDGCMYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPD-GSSFT 138
Query: 139 GTWVNGQQEG 148
GT+ +EG
Sbjct: 139 GTFYLSHREG 148
>gi|18139549 SET domain-containing protein 7 [Homo sapiens]
Length = 366
Score = 56.2 bits (134), Expect = 4e-08
Identities = 39/134 (29%), Positives = 65/134 (48%), Gaps = 3/134 (2%)
Query: 21 EGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQG 80
EG ++ G HG + D +EG++ G+++G+G + F +G+ G YV + GQG
Sbjct: 13 EGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQG 72
Query: 81 TFIYPDGSRYEGEWANDLRHGHGVYYYINND-TYTGEWFAHQRHGQGTYLYAETGSKYVG 139
+ Y DG +G + + +G Y + + G++ + RHG ++Y G VG
Sbjct: 73 VYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGV-CWIYYPDGGSLVG 131
Query: 140 TWVNGQQEGTAELI 153
VN E T E I
Sbjct: 132 E-VNEDGEMTGEKI 144
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 55.1 bits (131), Expect = 8e-08
Identities = 74/310 (23%), Positives = 117/310 (37%), Gaps = 27/310 (8%)
Query: 10 EEEGENDIGEYEG--GRNEAGERHGRGRARLPNGDTYEGSYEFGK-------RHGQGIYK 60
E G+ + GE EG G E E GRG + G+ G E GK G+G +
Sbjct: 779 ERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEE 838
Query: 61 FKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAH 120
G GE + G+G +G EGE + G G + GE
Sbjct: 839 EGEGEEEEGEGEEEEGEGKGE---EEGEEGEGEEEGEEGEGEG-----EEEEGEGEG-EE 889
Query: 121 QRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHRYQGKFLNKNPVGPGKYVFDVGC 180
+ G+G E + G ++EG + +G+ + G G+ G
Sbjct: 890 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGE 949
Query: 181 EQHGEYRLTDME-RGEEEEEEELVTVVPKWKATQITELALWTPTLPKKPTSTDGPGQDAP 239
E+ GE+ + E GE EEE E + + + ++ +G G++
Sbjct: 950 EEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEG 1009
Query: 240 GAESAGEPGEEAQALLEGFEGEMDMRPGDEDADVLREESREYDQEEFRYDMDEGNINSEE 299
E E E + +EG EGE + G+E+ E E ++ E + +E N EE
Sbjct: 1010 EGEGEEEEEGEVEGEVEGEEGEGE---GEEE-----EGEEEGEEREKEGEGEENRRNREE 1061
Query: 300 EETRQSDLQD 309
EE + Q+
Sbjct: 1062 EEEEEGKYQE 1071
Score = 48.9 bits (115), Expect = 6e-06
Identities = 82/314 (26%), Positives = 114/314 (36%), Gaps = 52/314 (16%)
Query: 5 GSEELEEEGENDIG--EYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFK 62
G + E EGE G E E G + ER G+ GD EG E + G+G K +
Sbjct: 753 GEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEE--ETEGRGEEKEE 810
Query: 63 NGARYIGEYVRNK-------KHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTG 115
G GE K + G+G +G EGE + G G + G
Sbjct: 811 GGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEE---EGEEGEG 867
Query: 116 EWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHRYQGKFLNKNPVGPGKYV 175
E + G+G E + G ++EG E +G+ + G GK
Sbjct: 868 EEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE-----GEEEGEGEGEEEEGEGKGE 922
Query: 176 FD------VGCEQHGEYRLTDMERGEEEEEEELVTVVPKWKATQITELALWTPTLPKKPT 229
+ G E+ GE D E GE EEEE +W+ +
Sbjct: 923 EEGEEGEGEGEEEEGEGEGEDGE-GEGEEEE------GEWEGEE---------------- 959
Query: 230 STDGPGQDAPGAESAGEPGEEAQALLEGFEGEMDMRPGDEDADV--LREESREYDQEEFR 287
+G G+ E GE GE EG EGE + G+E+ + EE E + EE
Sbjct: 960 -EEGEGEGEEEGEGEGEEGEGEGEEEEG-EGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017
Query: 288 YDMDEGNINSEEEE 301
EG + EE E
Sbjct: 1018 EGEVEGEVEGEEGE 1031
Score = 45.1 bits (105), Expect = 8e-05
Identities = 76/297 (25%), Positives = 111/297 (37%), Gaps = 41/297 (13%)
Query: 5 GSEELEEEGENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNG 64
G EE EGE E EG R E E+ G G+ G+ EG E K G+ + + G
Sbjct: 730 GGEEEHGEGE----EEEGDREEEEEKEGEGKEE-GEGEEVEGERE--KEEGERKKEERAG 782
Query: 65 ARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHG 124
GE G+G +G E E ++ G + GE + G
Sbjct: 783 KEEKGE--EEGDQGEGEEEETEGRGEEKEEGGEVEGG-------EVEEGKGEREEEEEEG 833
Query: 125 QGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHRYQGKFLNKNPVGPGKYVFDVGCEQHG 184
+G E G + G + EG E +G+ + G G+ G E+ G
Sbjct: 834 EGEEEEGE-GEEEEGEGEEEEGEGKGE----EEGEEGEGEEEGEEGEGE-----GEEEEG 883
Query: 185 EYRLTDMERGEEEEEEELVTVVPKWKATQITELALWTPTLPKKPTSTDGPGQDAPGAESA 244
E + GE EEEE + + E +G G++ G E
Sbjct: 884 EGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE-------------EGEGKGEE-EGEEGE 929
Query: 245 GEPGEEAQALLEGFEGEMDMRPGDEDADVLREESREYDQEEFRYDMDEGNINSEEEE 301
GE GEE + EG +GE + + + + EE +EE + +EG EEEE
Sbjct: 930 GE-GEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEE 985
Score = 33.9 bits (76), Expect = 0.19
Identities = 19/51 (37%), Positives = 22/51 (43%)
Query: 7 EELEEEGENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQG 57
EE E EGE + GE EG GE G G EG E + G+G
Sbjct: 984 EEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEG 1034
Score = 32.3 bits (72), Expect = 0.55
Identities = 29/99 (29%), Positives = 38/99 (38%), Gaps = 10/99 (10%)
Query: 5 GSEELEEEGENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNG 64
G E EEEGE GE E G E E G G G+ G+ G+G + +
Sbjct: 962 GEGEGEEEGE---GEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018
Query: 65 ARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHG 103
GE + G+G +G EGE + R G
Sbjct: 1019 GEVEGEV--EGEEGEG-----EGEEEEGEEEGEEREKEG 1050
Score = 28.5 bits (62), Expect = 7.9
Identities = 33/136 (24%), Positives = 54/136 (39%), Gaps = 27/136 (19%)
Query: 184 GEYRLTDMER-----GEEEEEEELVTVVPKWKATQITELALWTPTLPKKPTSTDGPGQDA 238
GE L + E GEE+E++E K + ++ E G G++
Sbjct: 692 GEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGG----------EEEHGEGEEE 741
Query: 239 PG-----AESAGEPGEEAQALLEGFEGEMDMRPGDEDADVLREESREYDQEEFRYDMDEG 293
G E GE EE + E EGE + G+ ++E R +E+ + D+G
Sbjct: 742 EGDREEEEEKEGEGKEEGEG--EEVEGEREKEEGER-----KKEERAGKEEKGEEEGDQG 794
Query: 294 NINSEEEETRQSDLQD 309
EE E R + ++
Sbjct: 795 EGEEEETEGRGEEKEE 810
>gi|224282170 MORN repeat containing 2 [Homo sapiens]
Length = 79
Score = 48.1 bits (113), Expect = 1e-05
Identities = 22/64 (34%), Positives = 33/64 (51%)
Query: 31 HGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRY 90
+G GR +G YEG ++ HG G Y F NGA+Y G + N+ G+G + G +
Sbjct: 2 NGFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEYTDIQGLEW 61
Query: 91 EGEW 94
G +
Sbjct: 62 SGNF 65
Score = 42.0 bits (97), Expect = 7e-04
Identities = 20/64 (31%), Positives = 35/64 (54%)
Query: 54 HGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTY 113
+G G + +GA Y G++ N HG GT+ +P+G++Y G + + G G Y I +
Sbjct: 2 NGFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEYTDIQGLEW 61
Query: 114 TGEW 117
+G +
Sbjct: 62 SGNF 65
Score = 38.5 bits (88), Expect = 0.008
Identities = 17/52 (32%), Positives = 30/52 (57%)
Query: 77 HGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTY 128
+G G + G+ YEG++ +++ HG G Y + N YTG + ++ G+G Y
Sbjct: 2 NGFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEY 53
Score = 32.0 bits (71), Expect = 0.71
Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 100 HGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAE 151
+G G + + Y G++ + HG GTY + G+KY G + + EG E
Sbjct: 2 NGFGRLEHFSGAVYEGQFKDNMFHGLGTYTF-PNGAKYTGNFNENRVEGEGE 52
>gi|223278407 MORN repeat containing 5 [Homo sapiens]
Length = 161
Score = 47.0 bits (110), Expect = 2e-05
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Query: 64 GARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRH 123
G++YIGEYV + G+ +I P + Y GE + + HG G Y+ + Y W +
Sbjct: 5 GSKYIGEYVDGRMEGKAKYILPTETIYVGEMKDGMFHGEGTLYFPSGSQYDAIW-ENGLA 63
Query: 124 GQGTYLYAE 132
+GTY +++
Sbjct: 64 IKGTYTFSD 72
Score = 47.0 bits (110), Expect = 2e-05
Identities = 21/58 (36%), Positives = 28/58 (48%)
Query: 41 GDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDL 98
G Y G Y G+ G+ Y Y+GE HG+GT +P GS+Y+ W N L
Sbjct: 5 GSKYIGEYVDGRMEGKAKYILPTETIYVGEMKDGMFHGEGTLYFPSGSQYDAIWENGL 62
Score = 43.1 bits (100), Expect = 3e-04
Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 9 LEEEGENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYI 68
+E G IGEY GR E G+ + LP Y G + G HG+G F +G++Y
Sbjct: 1 MEYTGSKYIGEYVDGRME-----GKAKYILPTETIYVGEMKDGMFHGEGTLYFPSGSQYD 55
Query: 69 GEYVRNKKHGQGTFIYPDGSRYE 91
+ N +GT+ + DG Y+
Sbjct: 56 AIW-ENGLAIKGTYTFSDGLHYD 77
Score = 30.4 bits (67), Expect = 2.1
Identities = 12/21 (57%), Positives = 17/21 (80%)
Query: 133 TGSKYVGTWVNGQQEGTAELI 153
TGSKY+G +V+G+ EG A+ I
Sbjct: 4 TGSKYIGEYVDGRMEGKAKYI 24
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 39.7 bits (91), Expect = 0.003
Identities = 34/127 (26%), Positives = 57/127 (44%), Gaps = 15/127 (11%)
Query: 182 QHGEYRLTDMERGEEEEEEELVTVVPKWKATQITELALWTPTLPKKPTSTDGPGQDAPGA 241
+H E L D E G EEEE + + +W+ + + PK+ S+
Sbjct: 2170 KHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRG----DKPKEKFSS-----QVDEV 2220
Query: 242 ESAGEPGEEAQALLEGFEGEMDMRPGDEDADVLREESREYDQEEFRYDMDEGNINSEEEE 301
ES EE ++LL+ E + + +E+ REE E ++EE R + +E EEEE
Sbjct: 2221 ESEEHFSEEMESLLDELEKQESLSSEEEEE---REEEEEREEEEVREEEEE---RKEEEE 2274
Query: 302 TRQSDLQ 308
+ ++
Sbjct: 2275 GEEKQVE 2281
>gi|82830424 gon-4-like isoform a [Homo sapiens]
Length = 2240
Score = 35.8 bits (81), Expect = 0.049
Identities = 34/117 (29%), Positives = 50/117 (42%), Gaps = 11/117 (9%)
Query: 168 PVGPGKYVFDVGCEQHGEYRLTDMERGEEEE----EEELVTVVPKWKATQITELALWTPT 223
PVGP G E+ E D+ + EE+E EE V VP+ + T E W +
Sbjct: 1445 PVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETM--EKLTWLAS 1502
Query: 224 LPKKPTSTDGPGQDAPGAESAGEPGEEAQALLEGFEGEMDMRPGDEDADVLREESRE 280
++ S +G ++ E EP EE + EG E ++ DE D +S E
Sbjct: 1503 --ERRMSQEGESEEENSQEENSEPEEEEEEEAEGME---SLQKEDEMTDEAVGDSAE 1554
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 35.8 bits (81), Expect = 0.049
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 10/121 (8%)
Query: 188 LTDMERGEEEEEEELVTVVPKWKATQITELALWTPTLPKKPTSTDGPGQDAPGAESAGEP 247
+++ ER E+E E L+ W+ + E+ + P + ES
Sbjct: 997 VSEEEREAEKEAERLMEQASCWEKEE-QEILSTRANSRQSPAKVQSKNKYLHSPESRPVT 1055
Query: 248 GEEAQALLEGFEGEMDMRPGDEDADVLREESREYDQEEFRYDMDEGNINSEEEETRQSDL 307
GE Q L E+ +E+ + EE E ++EE + DE EEEE + ++
Sbjct: 1056 GERGQLL------ELSKESSEEEEE---EEDEEEEEEEEEEEEDEEEEEEEEEEEEEENI 1106
Query: 308 Q 308
Q
Sbjct: 1107 Q 1107
>gi|58761530 polycomb group ring finger 6 isoform a [Homo sapiens]
Length = 350
Score = 35.8 bits (81), Expect = 0.049
Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 15/96 (15%)
Query: 225 PKKPTSTDGPGQ----DAPGAESAGEPGEEAQALLEGFEGEMDMRPGDEDADVLREESRE 280
P +GP APG + P E + L F G + DED ++ EE E
Sbjct: 36 PAPAAGEEGPAPLSETGAPGCSGSRPPELEPERSLGRFRGRFE----DEDEELEEEEELE 91
Query: 281 YDQEEFRYDM-------DEGNINSEEEETRQSDLQD 309
++EE DM + G +SE+EE R +L +
Sbjct: 92 EEEEEEEEDMSHFSLRLEGGRQDSEDEEERLINLSE 127
>gi|37655165 polycomb group ring finger 6 isoform b [Homo sapiens]
Length = 275
Score = 35.8 bits (81), Expect = 0.049
Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 15/96 (15%)
Query: 225 PKKPTSTDGPGQ----DAPGAESAGEPGEEAQALLEGFEGEMDMRPGDEDADVLREESRE 280
P +GP APG + P E + L F G + DED ++ EE E
Sbjct: 36 PAPAAGEEGPAPLSETGAPGCSGSRPPELEPERSLGRFRGRFE----DEDEELEEEEELE 91
Query: 281 YDQEEFRYDM-------DEGNINSEEEETRQSDLQD 309
++EE DM + G +SE+EE R +L +
Sbjct: 92 EEEEEEEEDMSHFSLRLEGGRQDSEDEEERLINLSE 127
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 35.4 bits (80), Expect = 0.065
Identities = 41/161 (25%), Positives = 63/161 (39%), Gaps = 29/161 (18%)
Query: 149 TAELIHLNHRYQGKFLNKNPVGPGKYVFDVGCEQHGEYRL-TDMERGEEEEEEELVTVVP 207
TA LI H + GKF G GE L G E+ + L+T
Sbjct: 354 TANLIGPGHSFYGKFS--------------GIRMEGEEALPAGSAAGPEQPQAGLLTPST 399
Query: 208 KWKATQITELALWTP--TLPKKPTSTDGPGQDAPGAESAGEPGEEAQALLEGFEGEMDMR 265
+T L TP ++P P ++ P + + G +S GE+ Q + +G +
Sbjct: 400 LLNLGGLTSSVLKTPITSVPLGPLASS-PTKSSEGKDSGAAEGEK-QEVGDGDCFSEKVE 457
Query: 266 PGDEDADVLREESREYDQEEFRYDMDEGNINSEEEETRQSD 306
P +E+A+ EE ++EE EEEE + D
Sbjct: 458 PAEEEAEEEEEEEEAEEEEE----------EEEEEEEEEED 488
>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 35.0 bits (79), Expect = 0.084
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 232 DGPGQDAPGAESAGEPGEEAQALLEGFEGEMDMRPGDEDADVLREESREYDQEEFRYDMD 291
D G+D E+ E GEE + L+ E E + GD+D D + EE E+ ++ D D
Sbjct: 191 DEEGEDEKDXEN--EDGEEEE--LDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDED 246
Query: 292 EGNINSEEE----ETRQSDLQD 309
E EEE E R+ + D
Sbjct: 247 EDEDEEEEESGKGENRKRETDD 268
Score = 29.3 bits (64), Expect = 4.6
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 232 DGPGQDAPGAESAGEPGEEAQALLEGFEGEMDMRPGDEDADVLREESREYDQEEFRYDMD 291
D Q+AP +++ + ++ + EG E E D D + + L EE E + E+ D D
Sbjct: 169 DPEDQEAPDSDAQVDGVDKEEEDEEG-EDEKDXENEDGEEEELDEE--EDEDEDVEGDDD 225
Query: 292 EGNINSEEEE 301
+ ++ EEEE
Sbjct: 226 KDEVSEEEEE 235
>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 35.0 bits (79), Expect = 0.084
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 232 DGPGQDAPGAESAGEPGEEAQALLEGFEGEMDMRPGDEDADVLREESREYDQEEFRYDMD 291
D G+D E+ E GEE + L+ E E + GD+D D + EE E+ ++ D D
Sbjct: 191 DEEGEDEKDXEN--EDGEEEE--LDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDED 246
Query: 292 EGNINSEEE----ETRQSDLQD 309
E EEE E R+ + D
Sbjct: 247 EDEDEEEEESGKGENRKRETDD 268
Score = 29.3 bits (64), Expect = 4.6
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 232 DGPGQDAPGAESAGEPGEEAQALLEGFEGEMDMRPGDEDADVLREESREYDQEEFRYDMD 291
D Q+AP +++ + ++ + EG E E D D + + L EE E + E+ D D
Sbjct: 169 DPEDQEAPDSDAQVDGVDKEEEDEEG-EDEKDXENEDGEEEELDEE--EDEDEDVEGDDD 225
Query: 292 EGNINSEEEE 301
+ ++ EEEE
Sbjct: 226 KDEVSEEEEE 235
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 35.0 bits (79), Expect = 0.084
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 9/92 (9%)
Query: 222 PTLPKKPTSTDGPGQDAPGAESAGEPGEEAQALLEGFE-GEMDMRPGDEDADVL---REE 277
P K +S+ D+ G E E E+ EG E E + PGDED + REE
Sbjct: 77 PFAVKADSSSVDECDDSDGTEDMDEKEED-----EGEEYSEDNDEPGDEDEEDEEGDREE 131
Query: 278 SREYDQEEFRYDMDEGNINSEEEETRQSDLQD 309
E ++E+ D D ++ EEEE + + ++
Sbjct: 132 EEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEE 163
Score = 29.6 bits (65), Expect = 3.5
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 241 AESAGEPGEEAQALLEG-FEGEMDMRPGDEDADVLREESREYDQEEFRYDMDEGNINSEE 299
+E EPG+E + EG E E ++ DED D E+ + + EE + +E EE
Sbjct: 111 SEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD---EDGEDVEDEEEEEEEEEEEEEEEE 167
Query: 300 EETRQ 304
E Q
Sbjct: 168 NEDHQ 172
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.135 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,839,832
Number of Sequences: 37866
Number of extensions: 817762
Number of successful extensions: 4426
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 120
Number of HSP's that attempted gapping in prelim test: 3569
Number of HSP's gapped (non-prelim): 665
length of query: 309
length of database: 18,247,518
effective HSP length: 102
effective length of query: 207
effective length of database: 14,385,186
effective search space: 2977733502
effective search space used: 2977733502
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.