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Search of human proteins with 182515228
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|182515228 mouse Mdm1 nuclear protein homolog isoform 1 [Homo
sapiens]
(714 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|182515228 mouse Mdm1 nuclear protein homolog isoform 1 [Homo ... 1445 0.0
gi|9910418 mouse Mdm1 nuclear protein homolog isoform 2 [Homo sa... 338 1e-92
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 55 2e-07
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 55 2e-07
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 53 1e-06
gi|150170670 piccolo isoform 2 [Homo sapiens] 45 2e-04
gi|150378539 piccolo isoform 1 [Homo sapiens] 45 2e-04
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 42 0.002
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 42 0.002
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 42 0.003
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 41 0.003
gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens] 40 0.006
gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens] 40 0.006
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 40 0.006
gi|55741677 SET domain containing 1A [Homo sapiens] 40 0.008
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 40 0.010
gi|215422388 death-domain associated protein isoform a [Homo sap... 40 0.010
gi|215422366 death-domain associated protein isoform b [Homo sap... 40 0.010
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H... 40 0.010
gi|46409304 glutamate-rich 1 [Homo sapiens] 40 0.010
gi|21735415 centromere protein B [Homo sapiens] 39 0.013
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 39 0.013
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 39 0.017
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 39 0.017
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 39 0.017
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 39 0.017
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 39 0.022
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 39 0.022
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 39 0.022
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 38 0.029
>gi|182515228 mouse Mdm1 nuclear protein homolog isoform 1 [Homo
sapiens]
Length = 714
Score = 1445 bits (3741), Expect = 0.0
Identities = 714/714 (100%), Positives = 714/714 (100%)
Query: 1 MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPY 60
MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPY
Sbjct: 1 MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPY 60
Query: 61 HDPQISKSLEWNGAISESNVVASPEPEAPETPKSQEAEQKDVTQERVHSLEASRVPKRTR 120
HDPQISKSLEWNGAISESNVVASPEPEAPETPKSQEAEQKDVTQERVHSLEASRVPKRTR
Sbjct: 61 HDPQISKSLEWNGAISESNVVASPEPEAPETPKSQEAEQKDVTQERVHSLEASRVPKRTR 120
Query: 121 SHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGLDRLLRKKAGLTVV 180
SHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGLDRLLRKKAGLTVV
Sbjct: 121 SHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGLDRLLRKKAGLTVV 180
Query: 181 PSYNALRNSEYQRQFVWKTSKETAPAFAANQVFHNKSQFVPPFKGNSVIHETEYKRNFKG 240
PSYNALRNSEYQRQFVWKTSKETAPAFAANQVFHNKSQFVPPFKGNSVIHETEYKRNFKG
Sbjct: 181 PSYNALRNSEYQRQFVWKTSKETAPAFAANQVFHNKSQFVPPFKGNSVIHETEYKRNFKG 240
Query: 241 LSPVKEPKLRNDLRENRNLETVSPERKSNKIDDRLKLEAEMELKDLHQPKRKLTPWKHQR 300
LSPVKEPKLRNDLRENRNLETVSPERKSNKIDDRLKLEAEMELKDLHQPKRKLTPWKHQR
Sbjct: 241 LSPVKEPKLRNDLRENRNLETVSPERKSNKIDDRLKLEAEMELKDLHQPKRKLTPWKHQR 300
Query: 301 LGKVNSEYRAKFLSPAQYLYKAGAWTHVKGNMPNQVKELREKAEFYRKRVQGTHFSRDHL 360
LGKVNSEYRAKFLSPAQYLYKAGAWTHVKGNMPNQVKELREKAEFYRKRVQGTHFSRDHL
Sbjct: 301 LGKVNSEYRAKFLSPAQYLYKAGAWTHVKGNMPNQVKELREKAEFYRKRVQGTHFSRDHL 360
Query: 361 NQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGDPTSHKTLQKCPSTEPEEKGNIVEEQ 420
NQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGDPTSHKTLQKCPSTEPEEKGNIVEEQ
Sbjct: 361 NQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGDPTSHKTLQKCPSTEPEEKGNIVEEQ 420
Query: 421 PQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFM 480
PQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFM
Sbjct: 421 PQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFM 480
Query: 481 GEQEKLDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAV 540
GEQEKLDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAV
Sbjct: 481 GEQEKLDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAV 540
Query: 541 LVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKKESRAVSLLTSPAAGIKTVDPLPLRED 600
LVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKKESRAVSLLTSPAAGIKTVDPLPLRED
Sbjct: 541 LVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKKESRAVSLLTSPAAGIKTVDPLPLRED 600
Query: 601 SEDNIHKFAEATLPVSKIPKYPTNPPGQLPSPPHVPSYWHPSRRIQGSLRDPEFQHNVGK 660
SEDNIHKFAEATLPVSKIPKYPTNPPGQLPSPPHVPSYWHPSRRIQGSLRDPEFQHNVGK
Sbjct: 601 SEDNIHKFAEATLPVSKIPKYPTNPPGQLPSPPHVPSYWHPSRRIQGSLRDPEFQHNVGK 660
Query: 661 ARMNNLQLPQHEAFNDEDEDRLSEISARSAASSLRAFQTLARAKKRKENFWGKT 714
ARMNNLQLPQHEAFNDEDEDRLSEISARSAASSLRAFQTLARAKKRKENFWGKT
Sbjct: 661 ARMNNLQLPQHEAFNDEDEDRLSEISARSAASSLRAFQTLARAKKRKENFWGKT 714
>gi|9910418 mouse Mdm1 nuclear protein homolog isoform 2 [Homo
sapiens]
Length = 222
Score = 338 bits (867), Expect = 1e-92
Identities = 166/167 (99%), Positives = 167/167 (100%)
Query: 1 MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPY 60
MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPY
Sbjct: 1 MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPY 60
Query: 61 HDPQISKSLEWNGAISESNVVASPEPEAPETPKSQEAEQKDVTQERVHSLEASRVPKRTR 120
HDPQISKSLEWNGAISESNVVASPEPEAPETPKSQEAEQKDVTQERVHSLEASRVPKRTR
Sbjct: 61 HDPQISKSLEWNGAISESNVVASPEPEAPETPKSQEAEQKDVTQERVHSLEASRVPKRTR 120
Query: 121 SHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGL 167
SHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNG+
Sbjct: 121 SHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGV 167
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 55.1 bits (131), Expect = 2e-07
Identities = 53/215 (24%), Positives = 86/215 (40%), Gaps = 17/215 (7%)
Query: 411 EEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEG 470
EEK EE+ ++ E+ V+A PV+ T+ +V+++ GEKEEE+ EEE
Sbjct: 486 EEKKEAAEEKEEEPEAEEEEVAAKKSPVKA--------TAPEVKEEEGEKEEEEGQEEEE 537
Query: 471 DRKTG---KQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRT 527
+ G QA G EK EK + ++ + +++ E+ K+ E T
Sbjct: 538 EEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVAT 597
Query: 528 HHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKKESRAVSLLTSPAA 587
+L V A + P K K P P + + + K+ +K V
Sbjct: 598 KEEL----VADAKVEKPEKAKSPVP--KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 651
Query: 588 GIKTVDPLPLREDSEDNIHKFAEATLPVSKIPKYP 622
G V P+ E + + K S +PK P
Sbjct: 652 GKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSP 686
Score = 31.6 bits (70), Expect = 2.7
Identities = 30/122 (24%), Positives = 51/122 (41%), Gaps = 8/122 (6%)
Query: 396 PTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRR-LAWDTENTSEDVQ 454
P K P + EEKG P+ EK P PV + + +++ E+
Sbjct: 621 PVEEKGKSPVPKSPVEEKGK--SPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA 678
Query: 455 KQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKM--KEGSDSSVSSEKGGR 512
K P K ++ + + + G+Q E+E+ +V+E K +K+ KE V +K
Sbjct: 679 KSPVPKSPVEEAKSKAEVGKGEQK---EEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAE 735
Query: 513 LP 514
P
Sbjct: 736 SP 737
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 55.1 bits (131), Expect = 2e-07
Identities = 53/215 (24%), Positives = 86/215 (40%), Gaps = 17/215 (7%)
Query: 411 EEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEG 470
EEK EE+ ++ E+ V+A PV+ T+ +V+++ GEKEEE+ EEE
Sbjct: 110 EEKKEAAEEKEEEPEAEEEEVAAKKSPVKA--------TAPEVKEEEGEKEEEEGQEEEE 161
Query: 471 DRKTG---KQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRT 527
+ G QA G EK EK + ++ + +++ E+ K+ E T
Sbjct: 162 EEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVAT 221
Query: 528 HHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKKESRAVSLLTSPAA 587
+L V A + P K K P P + + + K+ +K V
Sbjct: 222 KEEL----VADAKVEKPEKAKSPVP--KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 275
Query: 588 GIKTVDPLPLREDSEDNIHKFAEATLPVSKIPKYP 622
G V P+ E + + K S +PK P
Sbjct: 276 GKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSP 310
Score = 31.6 bits (70), Expect = 2.7
Identities = 30/122 (24%), Positives = 51/122 (41%), Gaps = 8/122 (6%)
Query: 396 PTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRR-LAWDTENTSEDVQ 454
P K P + EEKG P+ EK P PV + + +++ E+
Sbjct: 245 PVEEKGKSPVPKSPVEEKGK--SPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA 302
Query: 455 KQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKM--KEGSDSSVSSEKGGR 512
K P K ++ + + + G+Q E+E+ +V+E K +K+ KE V +K
Sbjct: 303 KSPVPKSPVEEAKSKAEVGKGEQK---EEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAE 359
Query: 513 LP 514
P
Sbjct: 360 SP 361
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 52.8 bits (125), Expect = 1e-06
Identities = 114/542 (21%), Positives = 197/542 (36%), Gaps = 86/542 (15%)
Query: 94 SQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAE-GASDVENNEGVTNHTP--VNENV 150
+QE + RV ++ + K+ S++S ++ G S ++EG+++ + E+
Sbjct: 213 NQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDE 272
Query: 151 ELEHSTKVLSENVDNGLDRLLRKKAGLTVV------PSYNALRNSEYQRQFVWKTSKETA 204
E E + SE+ D+ + + K+ V+ P + + +E ++ K +
Sbjct: 273 EEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQE---KRIHQPL 329
Query: 205 PAFAANQVFHNKSQFVPPF---------------------KGNSVIHETEYKRNFKGLSP 243
P + +Q +SQ P K SVI T N K LS
Sbjct: 330 PLASESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSL 389
Query: 244 VKEPKLRNDLRENRNLETVSPE--RKSNKIDDRLKLEAEMELKDLHQPKRKLTPWKHQRL 301
V + K ++ L SP+ + NK EL+ + ++ P +L
Sbjct: 390 VNQAKKETYMK----LIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAFP---SQL 442
Query: 302 GKVNSEYRAKFLSPAQYLYKAGAWTHVKGNMPNQVKELREKAEFYRKRVQGTHFSRDHLN 361
K S K + A KA T P Q E F + G H +
Sbjct: 443 KKQESSKSLKKVIAALSNPKA---TSSSPAHPKQTLENNHPNPFLTNALLGNHQPNGVIQ 499
Query: 362 QILSDSNCCWDVSSTTSSEGTVSSNIRA-----------LDLAGDPTSHKTLQKCPSTEP 410
++ ++ +++ T + ++ NI A L +G T PS P
Sbjct: 500 SVIQEAPLA--LTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSASP 557
Query: 411 ------EEKG-----NIVEEQ----PQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQK 455
+EK N V+ Q P K+ E+ + IP + D+E+++ED ++
Sbjct: 558 ILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSK----DSEDSNEDEEE 613
Query: 456 QPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEK------ 509
E++EEDD ++E D + E + E+ DK ++ SDS EK
Sbjct: 614 DDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLN 673
Query: 510 --GGRLPTPKLRELG-GIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDCLET 566
+ +P + G R H P A L S S+ +TS T
Sbjct: 674 KTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHSGT 733
Query: 567 SK 568
SK
Sbjct: 734 SK 735
Score = 32.3 bits (72), Expect = 1.6
Identities = 54/248 (21%), Positives = 95/248 (38%), Gaps = 29/248 (11%)
Query: 439 RRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMK 498
RRR D++ +D + +E+D++EE+ + K GK+ + E E + S + K
Sbjct: 1290 RRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEK 1349
Query: 499 EGSDSSVSSEKGGRL---PTPKLREL--GGIQRTHHDLTTPAVGGAVL--VSPSKMKPPA 551
+ S + R + LR + G + P GG + + +
Sbjct: 1350 QIEKLSKQQSQYRRKLFDASHSLRSVMFGQDRYRRRYWILPQCGGIFVEGMESGEGLEEI 1409
Query: 552 PEQRKRMTSQDCLETSKNDFTKKESRAVSLLTSPAAGIKTVDPLPLRED--SEDNIHKFA 609
++R+++ + ++ + F E+ SL S D +ED +DN + F
Sbjct: 1410 AKEREKLKKAESVQIKEEMF---ETSGDSLNCS------NTDHCEQKEDLKEKDNTNLFL 1460
Query: 610 EATLPVSK------IPKYPTNPPGQLPSPPH-----VPSYWHPSRRIQGSLRDPEFQHNV 658
+ SK + K P P P SY + + GS++ Q NV
Sbjct: 1461 QKPGSFSKLSKLLEVAKMPPESEVMTPKPNAGANGCTLSYQNSGKHSLGSVQSTATQSNV 1520
Query: 659 GKARMNNL 666
KA NNL
Sbjct: 1521 EKADSNNL 1528
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 45.1 bits (105), Expect = 2e-04
Identities = 95/462 (20%), Positives = 170/462 (36%), Gaps = 54/462 (11%)
Query: 58 VPYHDPQISKSLEWNGAISESNVVASPEPEAPETPKSQEAEQKDVTQERVHSLEASRVPK 117
+P + I K L+ + ES+ P +P E+ + + + +L + K
Sbjct: 1381 IPTDEKDILKGLKKDSFSQESS------PSSPSDLAKLESTVLSILEAQASTLADEKSEK 1434
Query: 118 RTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGLDRLLRKKAGL 177
+T+ H E D E + ++ E +E+ S + + E+ + D KK
Sbjct: 1435 KTQPHEVSP--EQPKDQEKTQSLS------ETLEITISEEEIKESQEERKDTF--KKDSQ 1484
Query: 178 TVVPSYNALRNSEYQRQFVWKTSKETAPAFAANQVFHNKSQFVPPFKGNSVIHET---EY 234
+PS ++ + + +FV + P + + +++ VP K + + + EY
Sbjct: 1485 QDIPSS---KDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEY 1541
Query: 235 KRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNKIDDRLK---LEAEMELKDLHQPKR 291
K+ S +E +R + E E S I ++LK E + K+ + K
Sbjct: 1542 KQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKG 1601
Query: 292 KLTPWKHQRLGKVNSEYRAKFLSPAQYLYKAGAWTHVKGNMPNQVKELR----EKAEFYR 347
K+T KH+RL + +S S + + +W ++ EL+ + E
Sbjct: 1602 KITAGKHRRLTRKSS------TSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEE 1655
Query: 348 KRVQG----THFSRDHLNQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGDP------- 396
V G F LN ++D TS + L P
Sbjct: 1656 LVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGE 1715
Query: 397 --TSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQ 454
+S P T P ++ +E + + K G S R R T ED
Sbjct: 1716 GSSSLHASSFTPGTSPTSVSSL-DEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIED-- 1772
Query: 455 KQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADK 496
+EEE EEE ++ KQ + +Q++ +KSK DK
Sbjct: 1773 ---SSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDK 1811
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 45.1 bits (105), Expect = 2e-04
Identities = 95/462 (20%), Positives = 170/462 (36%), Gaps = 54/462 (11%)
Query: 58 VPYHDPQISKSLEWNGAISESNVVASPEPEAPETPKSQEAEQKDVTQERVHSLEASRVPK 117
+P + I K L+ + ES+ P +P E+ + + + +L + K
Sbjct: 1381 IPTDEKDILKGLKKDSFSQESS------PSSPSDLAKLESTVLSILEAQASTLADEKSEK 1434
Query: 118 RTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGLDRLLRKKAGL 177
+T+ H E D E + ++ E +E+ S + + E+ + D KK
Sbjct: 1435 KTQPHEVSP--EQPKDQEKTQSLS------ETLEITISEEEIKESQEERKDTF--KKDSQ 1484
Query: 178 TVVPSYNALRNSEYQRQFVWKTSKETAPAFAANQVFHNKSQFVPPFKGNSVIHET---EY 234
+PS ++ + + +FV + P + + +++ VP K + + + EY
Sbjct: 1485 QDIPSS---KDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEY 1541
Query: 235 KRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNKIDDRLK---LEAEMELKDLHQPKR 291
K+ S +E +R + E E S I ++LK E + K+ + K
Sbjct: 1542 KQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKG 1601
Query: 292 KLTPWKHQRLGKVNSEYRAKFLSPAQYLYKAGAWTHVKGNMPNQVKELR----EKAEFYR 347
K+T KH+RL + +S S + + +W ++ EL+ + E
Sbjct: 1602 KITAGKHRRLTRKSS------TSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEE 1655
Query: 348 KRVQG----THFSRDHLNQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGDP------- 396
V G F LN ++D TS + L P
Sbjct: 1656 LVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGE 1715
Query: 397 --TSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQ 454
+S P T P ++ +E + + K G S R R T ED
Sbjct: 1716 GSSSLHASSFTPGTSPTSVSSL-DEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIED-- 1772
Query: 455 KQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADK 496
+EEE EEE ++ KQ + +Q++ +KSK DK
Sbjct: 1773 ---SSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDK 1811
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 42.4 bits (98), Expect = 0.002
Identities = 55/273 (20%), Positives = 93/273 (34%), Gaps = 26/273 (9%)
Query: 444 WDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEK-----LDVREKSKADKMK 498
W+ +N P D E + G A ++++ V + +D+M+
Sbjct: 82 WEIQNNPHASYSAPPPVSSSDSEAPEANPADGSDADEDDEDRGVMAVTAVTATAASDRME 141
Query: 499 EGSDSSVSSEKGG---RLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQR 555
SDS SS+ G + P K+ ++ DL + VSPS E+
Sbjct: 142 SDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQAS------VSPS-------EEE 188
Query: 556 KRMTSQDCLETSKNDFTKKESRAVSLLTSPAAGIKTVDPLPLREDSEDNIHKFAEATLPV 615
+S + +TS DFT ++ AV G + P DS+ PV
Sbjct: 189 NSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPV 248
Query: 616 SKIPKYPTNPPGQLPSPPHVPSYWHPSRRIQGSLRDPEFQHNVGKARMNNLQLPQHEAFN 675
+ ++ S V P R P+ + R + P + +
Sbjct: 249 AMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPK-----PRGRKPKPERPPSSSSS 303
Query: 676 DEDEDRLSEISARSAASSLRAFQTLARAKKRKE 708
D D D + IS R + AR ++ +E
Sbjct: 304 DSDSDEVDRISEWKRRDEARRRELEARRRREQE 336
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 42.4 bits (98), Expect = 0.002
Identities = 55/273 (20%), Positives = 93/273 (34%), Gaps = 26/273 (9%)
Query: 444 WDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEK-----LDVREKSKADKMK 498
W+ +N P D E + G A ++++ V + +D+M+
Sbjct: 82 WEIQNNPHASYSAPPPVSSSDSEAPEANPADGSDADEDDEDRGVMAVTAVTATAASDRME 141
Query: 499 EGSDSSVSSEKGG---RLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQR 555
SDS SS+ G + P K+ ++ DL + VSPS E+
Sbjct: 142 SDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQAS------VSPS-------EEE 188
Query: 556 KRMTSQDCLETSKNDFTKKESRAVSLLTSPAAGIKTVDPLPLREDSEDNIHKFAEATLPV 615
+S + +TS DFT ++ AV G + P DS+ PV
Sbjct: 189 NSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPV 248
Query: 616 SKIPKYPTNPPGQLPSPPHVPSYWHPSRRIQGSLRDPEFQHNVGKARMNNLQLPQHEAFN 675
+ ++ S V P R P+ + R + P + +
Sbjct: 249 AMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPK-----PRGRKPKPERPPSSSSS 303
Query: 676 DEDEDRLSEISARSAASSLRAFQTLARAKKRKE 708
D D D + IS R + AR ++ +E
Sbjct: 304 DSDSDEVDRISEWKRRDEARRRELEARRRREQE 336
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 41.6 bits (96), Expect = 0.003
Identities = 59/255 (23%), Positives = 98/255 (38%), Gaps = 39/255 (15%)
Query: 393 AGDPTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTI--PVRRRLAWDTENTS 450
A P + K +K S++ E+ EE+ Q +K V A + P + A +E++S
Sbjct: 70 ANGPVAKKAKKKASSSDSEDSSE-EEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSS 128
Query: 451 EDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKG 510
+ E DD++EE +K Q + Q K KA SDSS S ++
Sbjct: 129 SE--------ESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSS-SEDEP 179
Query: 511 GRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPE----QRKRMTSQDCLET 566
+ PK+ TP A +P K AP+ + +S +
Sbjct: 180 PKNQKPKI--------------TPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSS 225
Query: 567 SKNDFTKKESRAVSLLTSPAAGIKTVDPL-----PLREDS---EDNIHKFAEATLPVSKI 618
S +D ++++ A T P + P+ P R+ S + + + E P+
Sbjct: 226 SSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNK 285
Query: 619 P-KYPTNPPGQLPSP 632
P Y + PP P P
Sbjct: 286 PGPYSSVPPPSAPPP 300
Score = 35.0 bits (79), Expect = 0.24
Identities = 55/262 (20%), Positives = 96/262 (36%), Gaps = 24/262 (9%)
Query: 392 LAGDPTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLG----VSAPTIPVRRRLAWDTE 447
+A P T S+ E+ + EE+ +K K G V P+ P ++ + T+
Sbjct: 249 VAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKK-SLGTQ 307
Query: 448 NTSEDVQKQPGEKEEEDDNEE-----EGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSD 502
+ V+KQ + ED ++E E ++K +A + + K A+ + SD
Sbjct: 308 PPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSD 367
Query: 503 SSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQD 562
S SSE P + +PAV A +P + + R
Sbjct: 368 SD-SSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPA--AAPKQPVGGGQKLLTRKADSS 424
Query: 563 CLETSKNDFTKKESRAVSLLTSPAAGIKTVDPLPLRE----------DSEDNIHKFAEAT 612
E + +++++ + T P A K LP ++ DS+ + + E
Sbjct: 425 SSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEK 484
Query: 613 LPVSKIPKYPTN-PPGQLPSPP 633
S + K P G PS P
Sbjct: 485 TSKSAVKKKPQKVAGGAAPSKP 506
Score = 33.1 bits (74), Expect = 0.92
Identities = 32/134 (23%), Positives = 51/134 (38%), Gaps = 17/134 (12%)
Query: 403 QKCPSTEPEEKGNIVEEQPQKN--------TTEKLGVSAPTIPVRRRLAWDTENTSEDVQ 454
+K S+ EE+ + EE+ K T K +S P ++ + ++S D
Sbjct: 419 RKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPA----KQAPQGSRDSSSDSD 474
Query: 455 KQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSE-----K 509
E+EEE ++ +K K A K +K KA+ S S E K
Sbjct: 475 SSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLK 534
Query: 510 GGRLPTPKLRELGG 523
G P P+ + G
Sbjct: 535 GKGSPRPQAPKANG 548
>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
Length = 2440
Score = 41.2 bits (95), Expect = 0.003
Identities = 36/125 (28%), Positives = 53/125 (42%), Gaps = 15/125 (12%)
Query: 447 ENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKAD-KMKEGSDSSV 505
E ED ++ +KEEE +EEE D K E K + +EK K D +E +
Sbjct: 515 EEKEEDKAEKTEKKEEEKKDEEEKDEK--------EDSKENTKEKDKIDGTAEETEEREQ 566
Query: 506 SSEKGGRLPTPKLRELGGIQR--THHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDC 563
++ +G + + R G I R T+ A A P PP PE S +
Sbjct: 567 ATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEP----ISTEP 622
Query: 564 LETSK 568
+ETS+
Sbjct: 623 VETSR 627
Score = 31.6 bits (70), Expect = 2.7
Identities = 27/121 (22%), Positives = 50/121 (41%), Gaps = 7/121 (5%)
Query: 438 VRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKAD-K 496
VRR + + EK EE + E++ ++ K+ ++E+ D +E SK + K
Sbjct: 491 VRRNYGKRRGRNQQIARPSQEEKVEEKE-EDKAEKTEKKEEEKKDEEEKDEKEDSKENTK 549
Query: 497 MKEGSDSSVSSEKGGRLPTPKLRELGGIQ-----RTHHDLTTPAVGGAVLVSPSKMKPPA 551
K+ D + + TP+ R+ Q R +T A + + + +PP
Sbjct: 550 EKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEEPPP 609
Query: 552 P 552
P
Sbjct: 610 P 610
>gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens]
Length = 1123
Score = 40.4 bits (93), Expect = 0.006
Identities = 31/91 (34%), Positives = 49/91 (53%), Gaps = 12/91 (13%)
Query: 402 LQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKE 461
L + P+T PEE EE+ + LG A T+P R + ++E+T ED++ E++
Sbjct: 542 LPRQPTTHPEE----TEEELTEQQEVLLGEGALTMP--REGSTESESTQEDLE----EED 591
Query: 462 EEDDNEEEGD--RKTGKQAFMGEQEKLDVRE 490
EEDD EEE D + ++ G +E D+ E
Sbjct: 592 EEDDGEEEEDCIQVKDEEGESGAEEGPDLEE 622
>gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens]
Length = 1122
Score = 40.4 bits (93), Expect = 0.006
Identities = 31/91 (34%), Positives = 49/91 (53%), Gaps = 12/91 (13%)
Query: 402 LQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKE 461
L + P+T PEE EE+ + LG A T+P R + ++E+T ED++ E++
Sbjct: 541 LPRQPTTHPEE----TEEELTEQQEVLLGEGALTMP--REGSTESESTQEDLE----EED 590
Query: 462 EEDDNEEEGD--RKTGKQAFMGEQEKLDVRE 490
EEDD EEE D + ++ G +E D+ E
Sbjct: 591 EEDDGEEEEDCIQVKDEEGESGAEEGPDLEE 621
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 40.4 bits (93), Expect = 0.006
Identities = 29/125 (23%), Positives = 56/125 (44%), Gaps = 4/125 (3%)
Query: 446 TENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSV 505
+E E+ +++ E+EEE++ EEE D ++G Q+ ++ R K+K K ++ S
Sbjct: 299 SEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQS---DRSGSSGRRKAK-KKWRKDSPWVK 354
Query: 506 SSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDCLE 565
S K + P+ +E G+ L T + + +M+ P ++ C+
Sbjct: 355 PSRKRRKREPPRAKEPRGVSNDTSSLETERGFEELPLCSCRMEAPKIDRISERAGHKCMA 414
Query: 566 TSKND 570
T D
Sbjct: 415 TESVD 419
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 40.0 bits (92), Expect = 0.008
Identities = 53/252 (21%), Positives = 84/252 (33%), Gaps = 33/252 (13%)
Query: 406 PSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPV---------RRRLAWDTENTSEDVQKQ 456
PST EE + E++ + + G P R+ A D+E E Q+
Sbjct: 914 PSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEG-EEASQES 972
Query: 457 PGEKEEEDDNEEEGDR---------KTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSS 507
EK+EEDD E+E D K + GE E+ D K +G + S S
Sbjct: 973 SSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSD 1032
Query: 508 EKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDCLETS 567
+ + ++ + + S S+ E+ +R +
Sbjct: 1033 SESSS------------SSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPP 1080
Query: 568 KNDFTKKESRAVSLLTSPAAGIKTVDPLPLREDSEDNIHKFAEATLPVSKI--PKYPTNP 625
+ V + V PLP +E S E + P + + P+ P P
Sbjct: 1081 PREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGP 1140
Query: 626 PGQLPSPPHVPS 637
P P P PS
Sbjct: 1141 PAPAPRPDERPS 1152
Score = 34.7 bits (78), Expect = 0.32
Identities = 50/238 (21%), Positives = 89/238 (37%), Gaps = 20/238 (8%)
Query: 434 PTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQ--EKLDVREK 491
P+ V+R+ + SE+ + +P EED+++ E +++ G+ G + ++ + R K
Sbjct: 891 PSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGK 950
Query: 492 SKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPA 551
++ K + S E + K E D AV + + +
Sbjct: 951 TQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREE-----AVDTTKKETEVSD 1005
Query: 552 PEQRKRMTSQDCL----ETSKNDFT---KKESRAVSLLTSPAAGIKTVDPLPLREDSEDN 604
E + +S C +ND T + S + S +S ++ + SED
Sbjct: 1006 GEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDE 1065
Query: 605 IHKFAEATLPVSKIPKYPTNPPGQLPSPPHVPSYWHPSRRIQGSLRDPEFQHNVGKAR 662
+ A LP + P P P P+P VP R+ GS P + AR
Sbjct: 1066 EEEERPAALPSASPP--PREVPVPTPAPVEVP----VPERVAGSPVTPLPEQEASPAR 1117
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 39.7 bits (91), Expect = 0.010
Identities = 31/133 (23%), Positives = 57/133 (42%), Gaps = 22/133 (16%)
Query: 393 AGDPTSHKTLQKCPST-------EPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWD 445
+G+ S Q CPS E +E+ + EE+ ++ E+ A D
Sbjct: 415 SGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEE--------------ATD 460
Query: 446 TENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSV 505
+E + Q Q G++++E++ +EE + GK L + + + K+ S SS
Sbjct: 461 SEEEEDLEQMQEGQEDDEEE-DEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSG 519
Query: 506 SSEKGGRLPTPKL 518
+ GR+ +P L
Sbjct: 520 EQQNKGRIVSPSL 532
Score = 33.1 bits (74), Expect = 0.92
Identities = 31/141 (21%), Positives = 67/141 (47%), Gaps = 10/141 (7%)
Query: 430 GVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTG---KQAFMGEQEKL 486
G+++ P R D E+ E +++ E+EEE++ EE D + +Q G+++
Sbjct: 421 GMASQGCPSASRAETDDEDDEESDEEE--EEEEEEEEEEATDSEEEEDLEQMQEGQEDDE 478
Query: 487 DVREKSKADKMKEGSDSSVS----SEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLV 542
+ E+ +A K+G S +S S + P ++ G Q+ + +P++ +
Sbjct: 479 EEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPL 538
Query: 543 SPSKMKPPA-PEQRKRMTSQD 562
+PS + + EQ + +T ++
Sbjct: 539 APSSIDAESNGEQPEELTLEE 559
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 39.7 bits (91), Expect = 0.010
Identities = 31/133 (23%), Positives = 57/133 (42%), Gaps = 22/133 (16%)
Query: 393 AGDPTSHKTLQKCPST-------EPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWD 445
+G+ S Q CPS E +E+ + EE+ ++ E+ A D
Sbjct: 415 SGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEE--------------ATD 460
Query: 446 TENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSV 505
+E + Q Q G++++E++ +EE + GK L + + + K+ S SS
Sbjct: 461 SEEEEDLEQMQEGQEDDEEE-DEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSG 519
Query: 506 SSEKGGRLPTPKL 518
+ GR+ +P L
Sbjct: 520 EQQNKGRIVSPSL 532
Score = 33.1 bits (74), Expect = 0.92
Identities = 31/141 (21%), Positives = 67/141 (47%), Gaps = 10/141 (7%)
Query: 430 GVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTG---KQAFMGEQEKL 486
G+++ P R D E+ E +++ E+EEE++ EE D + +Q G+++
Sbjct: 421 GMASQGCPSASRAETDDEDDEESDEEE--EEEEEEEEEEATDSEEEEDLEQMQEGQEDDE 478
Query: 487 DVREKSKADKMKEGSDSSVS----SEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLV 542
+ E+ +A K+G S +S S + P ++ G Q+ + +P++ +
Sbjct: 479 EEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPL 538
Query: 543 SPSKMKPPA-PEQRKRMTSQD 562
+PS + + EQ + +T ++
Sbjct: 539 APSSIDAESNGEQPEELTLEE 559
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 39.7 bits (91), Expect = 0.010
Identities = 31/133 (23%), Positives = 57/133 (42%), Gaps = 22/133 (16%)
Query: 393 AGDPTSHKTLQKCPST-------EPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWD 445
+G+ S Q CPS E +E+ + EE+ ++ E+ A D
Sbjct: 427 SGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEE--------------ATD 472
Query: 446 TENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSV 505
+E + Q Q G++++E++ +EE + GK L + + + K+ S SS
Sbjct: 473 SEEEEDLEQMQEGQEDDEEE-DEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSG 531
Query: 506 SSEKGGRLPTPKL 518
+ GR+ +P L
Sbjct: 532 EQQNKGRIVSPSL 544
Score = 33.1 bits (74), Expect = 0.92
Identities = 31/141 (21%), Positives = 67/141 (47%), Gaps = 10/141 (7%)
Query: 430 GVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTG---KQAFMGEQEKL 486
G+++ P R D E+ E +++ E+EEE++ EE D + +Q G+++
Sbjct: 433 GMASQGCPSASRAETDDEDDEESDEEE--EEEEEEEEEEATDSEEEEDLEQMQEGQEDDE 490
Query: 487 DVREKSKADKMKEGSDSSVS----SEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLV 542
+ E+ +A K+G S +S S + P ++ G Q+ + +P++ +
Sbjct: 491 EEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPL 550
Query: 543 SPSKMKPPA-PEQRKRMTSQD 562
+PS + + EQ + +T ++
Sbjct: 551 APSSIDAESNGEQPEELTLEE 571
>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
sapiens]
Length = 1082
Score = 39.7 bits (91), Expect = 0.010
Identities = 39/151 (25%), Positives = 60/151 (39%), Gaps = 16/151 (10%)
Query: 445 DTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSS 504
+++N +D ++ G E + +EE+G RKT K+ K +A EGSDSS
Sbjct: 717 ESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKV---------PERKGEASSSDEGSDSS 767
Query: 505 VS---SEKGGRLPTPKLRELGGIQRT-HHDLTTPAVGGAVLVSPSKMKPPA--PEQRKRM 558
S SE +L ++T + PA L+ PP+ P +
Sbjct: 768 SSSSESEMTSESEEEQLEPASWSRKTPPSSKSAPATKEISLLDLEDFTPPSVQPVSPPAI 827
Query: 559 TSQDCLETSKNDFTKKESRAVSLLTSPAAGI 589
S L T +S V L SP +G+
Sbjct: 828 VSTS-LAADLEGLTLTDSTLVPSLLSPVSGV 857
Score = 31.6 bits (70), Expect = 2.7
Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 2/69 (2%)
Query: 457 PGEKEEED-DNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMK-EGSDSSVSSEKGGRLP 514
P E + D ++E E D K+ ++ GE E D+ K GS+S S E G R
Sbjct: 687 PTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKT 746
Query: 515 TPKLRELGG 523
K+ E G
Sbjct: 747 KKKVPERKG 755
>gi|46409304 glutamate-rich 1 [Homo sapiens]
Length = 443
Score = 39.7 bits (91), Expect = 0.010
Identities = 59/258 (22%), Positives = 104/258 (40%), Gaps = 16/258 (6%)
Query: 264 PERKSNKIDDRLKLEAEMELKDLH-QPKRKLTPWKHQRLGKVNSEY-----RAKFLSPAQ 317
PE S + + E +D H QPKR+ KH+ K + +A+
Sbjct: 83 PEPSSCGSPENASSGDDTEDQDPHDQPKRRRIR-KHKSKKKFKNPNNVLIEQAELEKQQS 141
Query: 318 YLYKAGAWTHVKGNM--PNQVKELREKAEFYRKRVQGTHFSR---DHLNQILSDSNCCWD 372
L + H G N+ ++L++K + RK+ G + Q SN
Sbjct: 142 LLQEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEG 201
Query: 373 VSSTTSSEGTVSSNIRALDLAGDPTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVS 432
V +G V ++ LAG+ T ++ + EE ++ + +E+
Sbjct: 202 VGEACEEDG-VDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTP 260
Query: 433 APTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEG-DRKTGKQAFMGEQEKLDVREK 491
A V+ D +T E+ + GE++ +D EE+G D + GE+E D E+
Sbjct: 261 AGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEE 320
Query: 492 SKADKMKEGSDSSVSSEK 509
AD +E D ++++EK
Sbjct: 321 DGADASEE--DDTITNEK 336
Score = 37.4 bits (85), Expect = 0.049
Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 3/102 (2%)
Query: 411 EEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEG 470
EE + E+ K+T E+ G A + R + + SE+ GE++ +D EE+G
Sbjct: 215 EEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDG 274
Query: 471 -DRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKGG 511
D GE++ D RE+ AD +E D + + E+ G
Sbjct: 275 VDTIEEDLTRAGEEDGKDTREEDGADASEE--DPTWAGEEEG 314
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 39.3 bits (90), Expect = 0.013
Identities = 20/66 (30%), Positives = 37/66 (56%), Gaps = 2/66 (3%)
Query: 445 DTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSS 504
+ E E+ +++ GE EEE++ EE + + G+ +GE+E +V E+ D +E +
Sbjct: 407 EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEE--EVEEEGDVDSDEEEEEDE 464
Query: 505 VSSEKG 510
SS +G
Sbjct: 465 ESSSEG 470
Score = 31.6 bits (70), Expect = 2.7
Identities = 11/27 (40%), Positives = 21/27 (77%)
Query: 445 DTENTSEDVQKQPGEKEEEDDNEEEGD 471
D+++ ED +++ E E++DD+EE+GD
Sbjct: 511 DSDSEEEDDEEEDDEDEDDDDDEEDGD 537
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 39.3 bits (90), Expect = 0.013
Identities = 31/106 (29%), Positives = 45/106 (42%), Gaps = 3/106 (2%)
Query: 445 DTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSS 504
D E ED +++ E+EEE++ EEE + + A + E L R S ++ + +D S
Sbjct: 741 DEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRS 800
Query: 505 VSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGG--AVLVSPSKMK 548
L + G DL P G VLVSP MK
Sbjct: 801 QEGAPSTLLADDQKESRGRASMADGDL-EPEEGSKTLVLVSPGDMK 845
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 38.9 bits (89), Expect = 0.017
Identities = 48/228 (21%), Positives = 91/228 (39%), Gaps = 22/228 (9%)
Query: 409 EPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEE 468
E ++ + E+ Q+ EKL +++ +E +KQ KEE + E
Sbjct: 474 EKNKQEKELRERQQEEQKEKLRKEEQEQKAKKK---QEAEENEITEKQQKAKEEMEKKES 530
Query: 469 EGDRKTGKQAFMGEQEKLD-VREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRT 527
E +K K+ +++ V+ +SK++ + SV ++G R PTP++++
Sbjct: 531 EQAKKEDKETSAKRGKEITGVKRQSKSEHETSDAKKSVE-DRGKRCPTPEIQKKSTGDVP 589
Query: 528 HHDLTTPAVGGAVLVSPSKMK--PPAPEQRKRMTSQDCLETSKN-----DFTKKESRAVS 580
H +T + G P K+K P + R +D +T +N T+ S +
Sbjct: 590 HTSVTGDSGSG----KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMG 645
Query: 581 LLTS--PAAGIKTVDPLP----LREDSEDNIHKFAEATLPVSKIPKYP 622
+ P+ K +DP+ + +H + P S P P
Sbjct: 646 RIVPGLPSGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTP 693
Score = 32.7 bits (73), Expect = 1.2
Identities = 34/165 (20%), Positives = 73/165 (44%), Gaps = 13/165 (7%)
Query: 442 LAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGS 501
L + ++++++ E+++E +EE ++K K+ E E + ++K+K + K+ S
Sbjct: 471 LLMEKNKQEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKES 530
Query: 502 DSSVSSEKGGRLPTPKLRELGGIQR---THHDLTTPAVGGAVLVSPSKMKPPAPEQRKRM 558
+ + +K + +E+ G++R + H+ + V + P PE +K+
Sbjct: 531 EQAKKEDK--ETSAKRGKEITGVKRQSKSEHETSDAKKS----VEDRGKRCPTPEIQKKS 584
Query: 559 TSQDCLETSKNDFTKKESRAVSLLTSPAAGIKTVDPLPLREDSED 603
T D TS + + P +GI RED++D
Sbjct: 585 TG-DVPHTSVTG-DSGSGKPFKIKGQPESGILRTG--TFREDTDD 625
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 38.9 bits (89), Expect = 0.017
Identities = 48/228 (21%), Positives = 91/228 (39%), Gaps = 22/228 (9%)
Query: 409 EPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEE 468
E ++ + E+ Q+ EKL +++ +E +KQ KEE + E
Sbjct: 474 EKNKQEKELRERQQEEQKEKLRKEEQEQKAKKK---QEAEENEITEKQQKAKEEMEKKES 530
Query: 469 EGDRKTGKQAFMGEQEKLD-VREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRT 527
E +K K+ +++ V+ +SK++ + SV ++G R PTP++++
Sbjct: 531 EQAKKEDKETSAKRGKEITGVKRQSKSEHETSDAKKSVE-DRGKRCPTPEIQKKSTGDVP 589
Query: 528 HHDLTTPAVGGAVLVSPSKMK--PPAPEQRKRMTSQDCLETSKN-----DFTKKESRAVS 580
H +T + G P K+K P + R +D +T +N T+ S +
Sbjct: 590 HTSVTGDSGSG----KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMG 645
Query: 581 LLTS--PAAGIKTVDPLP----LREDSEDNIHKFAEATLPVSKIPKYP 622
+ P+ K +DP+ + +H + P S P P
Sbjct: 646 RIVPGLPSGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTP 693
Score = 32.7 bits (73), Expect = 1.2
Identities = 34/165 (20%), Positives = 73/165 (44%), Gaps = 13/165 (7%)
Query: 442 LAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGS 501
L + ++++++ E+++E +EE ++K K+ E E + ++K+K + K+ S
Sbjct: 471 LLMEKNKQEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKES 530
Query: 502 DSSVSSEKGGRLPTPKLRELGGIQR---THHDLTTPAVGGAVLVSPSKMKPPAPEQRKRM 558
+ + +K + +E+ G++R + H+ + V + P PE +K+
Sbjct: 531 EQAKKEDK--ETSAKRGKEITGVKRQSKSEHETSDAKKS----VEDRGKRCPTPEIQKKS 584
Query: 559 TSQDCLETSKNDFTKKESRAVSLLTSPAAGIKTVDPLPLREDSED 603
T D TS + + P +GI RED++D
Sbjct: 585 TG-DVPHTSVTG-DSGSGKPFKIKGQPESGILRTG--TFREDTDD 625
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 38.9 bits (89), Expect = 0.017
Identities = 48/228 (21%), Positives = 91/228 (39%), Gaps = 22/228 (9%)
Query: 409 EPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEE 468
E ++ + E+ Q+ EKL +++ +E +KQ KEE + E
Sbjct: 474 EKNKQEKELRERQQEEQKEKLRKEEQEQKAKKK---QEAEENEITEKQQKAKEEMEKKES 530
Query: 469 EGDRKTGKQAFMGEQEKLD-VREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRT 527
E +K K+ +++ V+ +SK++ + SV ++G R PTP++++
Sbjct: 531 EQAKKEDKETSAKRGKEITGVKRQSKSEHETSDAKKSVE-DRGKRCPTPEIQKKSTGDVP 589
Query: 528 HHDLTTPAVGGAVLVSPSKMK--PPAPEQRKRMTSQDCLETSKN-----DFTKKESRAVS 580
H +T + G P K+K P + R +D +T +N T+ S +
Sbjct: 590 HTSVTGDSGSG----KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMG 645
Query: 581 LLTS--PAAGIKTVDPLP----LREDSEDNIHKFAEATLPVSKIPKYP 622
+ P+ K +DP+ + +H + P S P P
Sbjct: 646 RIVPGLPSGWAKFLDPITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTP 693
Score = 32.7 bits (73), Expect = 1.2
Identities = 34/165 (20%), Positives = 73/165 (44%), Gaps = 13/165 (7%)
Query: 442 LAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGS 501
L + ++++++ E+++E +EE ++K K+ E E + ++K+K + K+ S
Sbjct: 471 LLMEKNKQEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKES 530
Query: 502 DSSVSSEKGGRLPTPKLRELGGIQR---THHDLTTPAVGGAVLVSPSKMKPPAPEQRKRM 558
+ + +K + +E+ G++R + H+ + V + P PE +K+
Sbjct: 531 EQAKKEDK--ETSAKRGKEITGVKRQSKSEHETSDAKKS----VEDRGKRCPTPEIQKKS 584
Query: 559 TSQDCLETSKNDFTKKESRAVSLLTSPAAGIKTVDPLPLREDSED 603
T D TS + + P +GI RED++D
Sbjct: 585 TG-DVPHTSVTG-DSGSGKPFKIKGQPESGILRTG--TFREDTDD 625
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 38.9 bits (89), Expect = 0.017
Identities = 25/100 (25%), Positives = 52/100 (52%), Gaps = 7/100 (7%)
Query: 409 EPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNE- 467
E EE+ + +E+ + E+L A R RL + E+ ++Q EK++++ E
Sbjct: 416 EQEEQERVEKEEQDRLEREELKRKAEE--ERLRLEEEARKQEEERKRQEEEKKKQEGEEK 473
Query: 468 ----EEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDS 503
EE RK ++ + E+++ + +EK+ +K KE +++
Sbjct: 474 RKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAET 513
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 38.5 bits (88), Expect = 0.022
Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 4/63 (6%)
Query: 447 ENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVS 506
+ E+ +K+ G+ +E +D +E+GD+K GK + E EK RE K D + G++
Sbjct: 195 DEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEK--EREDGKED--EGGNEEEAG 250
Query: 507 SEK 509
EK
Sbjct: 251 KEK 253
Score = 34.3 bits (77), Expect = 0.41
Identities = 28/105 (26%), Positives = 50/105 (47%), Gaps = 21/105 (20%)
Query: 417 VEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGD----- 471
V+E+ ++ TEK G + +A + +N ED QK+ +EED NEE+G+
Sbjct: 100 VKEENIEDATEKGGEK------KEAVAAEVKNEEED-QKE----DEEDQNEEKGEAGKED 148
Query: 472 -----RKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKGG 511
+ GK+ G ++ D +EK K ++G + ++ G
Sbjct: 149 KDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKG 193
Score = 31.2 bits (69), Expect = 3.5
Identities = 29/105 (27%), Positives = 40/105 (38%), Gaps = 18/105 (17%)
Query: 416 IVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEK----------EEEDD 465
+VEE +N + + E ED ++ GEK EEED
Sbjct: 71 VVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQ 130
Query: 466 NEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKG 510
E+E D+ K GE K D EK + D G + +EKG
Sbjct: 131 KEDEEDQNEEK----GEAGKEDKDEKGEED----GKEDKNGNEKG 167
Score = 31.2 bits (69), Expect = 3.5
Identities = 19/66 (28%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
Query: 455 KQPGEKEEEDD---NEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKGG 511
K+ G+K+E D E+E +R+ GK+ G +E+ +EK + +EG + E G
Sbjct: 215 KEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAG-KEKEDLKEEEEGKEEDEIKEDDG 273
Query: 512 RLPTPK 517
+ P+
Sbjct: 274 KKEEPQ 279
Score = 30.8 bits (68), Expect = 4.6
Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 13/68 (19%)
Query: 445 DTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSS 504
D + ED +++ +++EE+D +E GD K + K K DK KEG D
Sbjct: 181 DGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDG------------KEKGDK-KEGKDVK 227
Query: 505 VSSEKGGR 512
V ++ R
Sbjct: 228 VKEDEKER 235
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 38.5 bits (88), Expect = 0.022
Identities = 59/236 (25%), Positives = 93/236 (39%), Gaps = 49/236 (20%)
Query: 407 STEPEEKGNIVEEQPQKNTTEKLGV-----------SAPT-------IPVRRRLAWDTEN 448
S+ EEKG+ +E+P+K V S P P R N
Sbjct: 207 SSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRN 266
Query: 449 TSEDVQKQPGEKEEEDDNEEEGDRKTGK-------QAFMGEQEKLD--VREKSKADKMKE 499
+ +++ E+EEEDD EEEGD + K + F E E++ E+ ++ K
Sbjct: 267 LKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKT 326
Query: 500 GSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAP---EQRK 556
S E+GGR R +++H A +MK +P E+R+
Sbjct: 327 RSQEQEVLERGGRF----TRSQEEARKSHL---------ARQQQEKEMKTTSPLEEEERE 373
Query: 557 RMTSQDCLETSKNDF------TKKESRAVSLLTSPAAGIKTVDPLPLREDSEDNIH 606
+SQ E SK+ +K++ V+L A+ +T PL +E S H
Sbjct: 374 IKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPPPH 429
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 38.5 bits (88), Expect = 0.022
Identities = 93/450 (20%), Positives = 160/450 (35%), Gaps = 42/450 (9%)
Query: 82 ASPEPEAPETPKSQE---AEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNE 138
ASPE EA K + AE K +E S + P++ +S A A+ + ++ E
Sbjct: 510 ASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKS-PAKEEAKSPPEAKSPE 568
Query: 139 GVTNHTPVNENVELEHSTKVLSENVDNGLDRLLRKKAGLTVVPSYNALRNSEYQRQFVWK 198
+P E++ K S + K P ++ + V +
Sbjct: 569 KEEAKSPA----EVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE 624
Query: 199 TSKETAPAFAANQVFH-NKSQFVPPFKGNSVIHETEYKRNFKGLSPVK-EPKLRNDLREN 256
+K A + + K + P K S E E K K SPVK E K +
Sbjct: 625 EAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE-EAKSPEKAKSPVKAEAKSPEKAKSP 683
Query: 257 RNLETVSPERKSNKIDDRLKL--EAEMELKD-LHQPKRKLTPWKHQRLGKVNSEYRAKFL 313
E SPE+ + + + K +A+ +K+ P++ +P K + AK
Sbjct: 684 VKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEE----------AKTP 733
Query: 314 SPAQYLYKAGAWTHVKGNMPNQVKELREKAEFYRKRVQGTHFSRDHLNQILSDSNCCWDV 373
A+ K A + K P + K L K+ + + S + S +V
Sbjct: 734 EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEV 793
Query: 374 SSTTSSEGTVSSNIRALDLAGDPTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSA 433
S ++ + + +A + K K P E E+ + ++P K E+ +
Sbjct: 794 KSPEKAKSPLKEDAKAPE---KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT 850
Query: 434 P-----------TIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRK----TGKQA 478
P P + E E ++P E + E EE D+K K+A
Sbjct: 851 PKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEA 910
Query: 479 FMGEQEKLDVREKSKADKMKEGSDSSVSSE 508
+ K D + K K + K+ D + + E
Sbjct: 911 PAKVEVKEDAKPKEKTEVAKKEPDDAKAKE 940
Score = 37.7 bits (86), Expect = 0.037
Identities = 50/200 (25%), Positives = 81/200 (40%), Gaps = 20/200 (10%)
Query: 402 LQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGE-- 459
L K PS K V+ + + EK + + TE +E+ +K+ E
Sbjct: 426 LPKIPSVSTHIK---VKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEE 482
Query: 460 -KEEEDDNEEE---GDRKT----GKQAFMGEQE-KLDVREKSKA-----DKMKEGSDSSV 505
KEEE EEE G+ +T ++A E+E K V+E++K+ KE + S
Sbjct: 483 GKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPA 542
Query: 506 SSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDCLE 565
+ + +P E A A + SP K K PA E+ K E
Sbjct: 543 EVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPE 602
Query: 566 TSKNDFTKKESRAVSLLTSP 585
+K+ K+E+++ + SP
Sbjct: 603 KAKSP-VKEEAKSPAEAKSP 621
Score = 35.0 bits (79), Expect = 0.24
Identities = 50/212 (23%), Positives = 78/212 (36%), Gaps = 19/212 (8%)
Query: 447 ENTSE-DVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSV 505
E T E V ++ E+EE++ EEEG + G GE+E+ E + + ++ +
Sbjct: 459 EQTEETQVTEEVTEEEEKEAKEEEGKEEEG-----GEEEE---AEGGEEETKSPPAEEAA 510
Query: 506 SSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQRK---RMTSQD 562
S EK + P + E A A + SP K K PA E+ K S +
Sbjct: 511 SPEKEAKSPVKE--EAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPE 568
Query: 563 CLETSKNDFTKKESRAVSLLTSPA-AGIKTVDPLPLREDSEDNIHKFAEATLPVSKIPKY 621
E K +A S A + + P + ++ AEA PV K
Sbjct: 569 KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPV----KE 624
Query: 622 PTNPPGQLPSPPHVPSYWHPSRRIQGSLRDPE 653
P ++ SP S + + PE
Sbjct: 625 EAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE 656
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 38.1 bits (87), Expect = 0.029
Identities = 76/381 (19%), Positives = 134/381 (35%), Gaps = 45/381 (11%)
Query: 250 RNDLRENRNLETVSPERKSNKIDDRLKLEAEMELKDLHQPKRKLTP------------WK 297
R ++RE+RN ERKS K R + E + + +R+ +P K
Sbjct: 804 REEIREDRNPRDGHDERKSKK---RYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEK 860
Query: 298 HQRLGKVNSEYRAKFLSPAQYLY-KAGAWTHVKGNMPNQVKELREKAEFYRKRVQGTHFS 356
H+ L +V ++ LSP+ + G W + R + + +++V
Sbjct: 861 HRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQ 920
Query: 357 RDHLNQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGDPTSHKT-LQKCPSTEPEEKGN 415
R+ + S D+ SE +S D A D K +QK P + +E
Sbjct: 921 REQTEILESSRMRAQDIIGHHQSEDRETS-----DRAHDENKKKAKIQKKPIKKKKEDDV 975
Query: 416 IVEEQPQKNTTE-------KLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEE 468
+E + T+E K G +I +R+ + + S++ Q +K+
Sbjct: 976 GIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPP 1035
Query: 469 EGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTH 528
++ + G+ L+ +K + + SD V P E +
Sbjct: 1036 ITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDV----------PDRTE---VTEAE 1082
Query: 529 HDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTS--QDCLETSKNDFTKKESRAVSLLTSPA 586
H T G S + PP P T+ T+ T + A+++ TS A
Sbjct: 1083 HTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTS-A 1141
Query: 587 AGIKTVDPLPLREDSEDNIHK 607
T + EDS H+
Sbjct: 1142 TPTNTTNNTFANEDSHRKCHR 1162
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,722,491
Number of Sequences: 37866
Number of extensions: 1522659
Number of successful extensions: 11310
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 90
Number of HSP's successfully gapped in prelim test: 336
Number of HSP's that attempted gapping in prelim test: 8771
Number of HSP's gapped (non-prelim): 1970
length of query: 714
length of database: 18,247,518
effective HSP length: 109
effective length of query: 605
effective length of database: 14,120,124
effective search space: 8542675020
effective search space used: 8542675020
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.