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Search of human proteins with 18152787
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18152787 neuralized-like protein 2 [Homo sapiens]
(285 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18152787 neuralized-like protein 2 [Homo sapiens] 583 e-167
gi|53829370 neuralized homolog 4 isoform 1 [Homo sapiens] 87 2e-17
gi|53829368 neuralized homolog 4 isoform 2 [Homo sapiens] 87 2e-17
gi|217416388 neuralized homolog 1B [Homo sapiens] 63 3e-10
gi|223278368 neuralized-like [Homo sapiens] 57 2e-08
gi|195976771 cytokine-inducible SH2-containing protein isoform 1... 33 0.29
gi|21614507 cytokine-inducible SH2-containing protein isoform 2 ... 33 0.29
gi|18254474 ankyrin repeat and SOCS box-containing protein 11 is... 33 0.37
gi|60218887 ankyrin repeat and SOCS box-containing protein 11 is... 33 0.37
gi|39930571 leucine rich repeat containing 56 [Homo sapiens] 32 0.64
gi|21618354 suppressor of cytokine signaling 5 [Homo sapiens] 32 0.83
gi|7662240 suppressor of cytokine signaling 5 [Homo sapiens] 32 0.83
gi|81295809 pericentrin [Homo sapiens] 31 1.1
gi|46559761 PDZ domain containing 4 [Homo sapiens] 31 1.1
gi|4507263 suppressor of cytokine signaling-2 [Homo sapiens] 30 1.9
gi|4557679 jagged 1 precursor [Homo sapiens] 29 4.1
gi|239754042 PREDICTED: similar to hCG1646049 [Homo sapiens] 29 4.1
gi|239748572 PREDICTED: similar to hCG1646049 [Homo sapiens] 29 4.1
gi|169167670 PREDICTED: similar to hCG1646049 [Homo sapiens] 29 4.1
gi|217416354 sphingosine kinase type 1-interacting protein isofo... 29 4.1
gi|217416352 sphingosine kinase type 1-interacting protein isofo... 29 4.1
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 29 5.4
gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo ... 29 5.4
gi|193794843 BEN domain containing 2 [Homo sapiens] 28 7.0
gi|212286172 RNA polymerase I polypeptide B isoform 2 [Homo sapi... 28 9.2
gi|33469941 RNA polymerase I polypeptide B isoform 1 [Homo sapiens] 28 9.2
gi|194578891 abhydrolase domain-containing protein 1 [Homo sapiens] 28 9.2
gi|46560555 transmembrane protein 132E [Homo sapiens] 28 9.2
>gi|18152787 neuralized-like protein 2 [Homo sapiens]
Length = 285
Score = 583 bits (1504), Expect = e-167
Identities = 285/285 (100%), Positives = 285/285 (100%)
Query: 1 MAAASEPVDSGALWGLERPEPPPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPL 60
MAAASEPVDSGALWGLERPEPPPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPL
Sbjct: 1 MAAASEPVDSGALWGLERPEPPPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPL 60
Query: 61 APGQVFLVEIEEKELGWCGHLRLGLTALDPASLAPVPEFSLPDLVNLGHTWVFAITRHHN 120
APGQVFLVEIEEKELGWCGHLRLGLTALDPASLAPVPEFSLPDLVNLGHTWVFAITRHHN
Sbjct: 61 APGQVFLVEIEEKELGWCGHLRLGLTALDPASLAPVPEFSLPDLVNLGHTWVFAITRHHN 120
Query: 121 RVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYSHLLDQLYELNV 180
RVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYSHLLDQLYELNV
Sbjct: 121 RVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYSHLLDQLYELNV 180
Query: 181 LPPTARRSRLGVLFCPRPDGTADMHIIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVR 240
LPPTARRSRLGVLFCPRPDGTADMHIIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVR
Sbjct: 181 LPPTARRSRLGVLFCPRPDGTADMHIIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVR 240
Query: 241 LVQLEYGLPSLQTLCRLVIQRSMVHRLAIDGLHLPKELKDFCKYE 285
LVQLEYGLPSLQTLCRLVIQRSMVHRLAIDGLHLPKELKDFCKYE
Sbjct: 241 LVQLEYGLPSLQTLCRLVIQRSMVHRLAIDGLHLPKELKDFCKYE 285
>gi|53829370 neuralized homolog 4 isoform 1 [Homo sapiens]
Length = 1562
Score = 87.0 bits (214), Expect = 2e-17
Identities = 68/224 (30%), Positives = 99/224 (44%), Gaps = 60/224 (26%)
Query: 25 RFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLRLG 84
RFH G N+ ++ GTRA R +AHG+ FS + L +VF V++EE + W G LRLG
Sbjct: 915 RFHSTCGKNVTLEEDGTRAVRAAGYAHGLVFSTKELRAEEVFEVKVEELDEKWAGSLRLG 974
Query: 85 LTALDPASLAPVPEFSLPDLVNLGHTWVFAITRHHNRVPREGRPEAEAAAPSRPPTLLVE 144
LT L P + P A P PP+L
Sbjct: 975 LTTLAPGEMG---------------------------------PGAGGGGPGLPPSL--- 998
Query: 145 PYLR------IEQFRIPRDRLVGRSRPGLYSHLLDQLYELNVLPPTARRSRLGVLFCPRP 198
P LR + + RD + R Y L++L SR+GV R
Sbjct: 999 PELRTKTTWMVSSCEVRRDGQLQRMN---YGRNLERL---------GVGSRVGV----RR 1042
Query: 199 DGTADMHIIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVRLV 242
MHI+++GEDMGP+A G+ A+ ++AV+D++ + V +V
Sbjct: 1043 GADDTMHILVDGEDMGPAATGI--AKNVWAVLDLYGPVRGVSIV 1084
Score = 56.6 bits (135), Expect = 2e-08
Identities = 55/201 (27%), Positives = 80/201 (39%), Gaps = 58/201 (28%)
Query: 47 ESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLRLGLTALDPASLAPVPEFSLPDLVN 106
+ F HG+ SREPL G+VF V I+ K W G + +G+TALDP+ L +F
Sbjct: 68 QEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVL----DFPSSATGL 123
Query: 107 LGHTWVFAITRHHNRVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPG 166
G +WV + + RD GRS
Sbjct: 124 KGGSWV------------------------------------VSGCSVLRD---GRSVLE 144
Query: 167 LYSHLLDQLYELNVLPPTARRSRLGVLFCPRPDGTADMHIIINGEDMGPSARGLPAAQPL 226
Y LDQL E R+GV ++ + +NG D G +A GLP +
Sbjct: 145 EYGQDLDQLGE---------GDRVGV----ERTVAGELRLWVNGRDCGVAATGLPPR--V 189
Query: 227 YAVVDVFASTKSVRLVQLEYG 247
+AVVD++ + ++ E G
Sbjct: 190 WAVVDLYGKCTQITVLPPEPG 210
Score = 50.8 bits (120), Expect = 1e-06
Identities = 62/228 (27%), Positives = 85/228 (37%), Gaps = 65/228 (28%)
Query: 20 EPPPTRFHRVHGANIRVDPSGTRATR---VESFAHGVCFSREPLAPGQVFLVEIEEKELG 76
EP FH G + G A R + F HGV S L G+VF V I++
Sbjct: 517 EPERLLFHPNCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDK 576
Query: 77 WCGHLRLGLTALDPASLAPVPEFSLPD-LVNL-GHTWVFAITRHHNRVPREGRPEAEAAA 134
W G + +G+T +PA L LP + NL TW+ N V G
Sbjct: 577 WAGSIEIGVTTHNPAYL------QLPSTMTNLRSGTWMMT----GNGVMHNG-------- 618
Query: 135 PSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYSHLLDQLYELNVLPPTARRSRLGVLF 194
T+L E Y H LD+L +GV+
Sbjct: 619 ----TTILDE-----------------------YGHNLDRL---------KAGDTVGVV- 641
Query: 195 CPRPDGTADMHIIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVRLV 242
R DGT +H +NG GP+A +P +YAVVD++ +V
Sbjct: 642 -RREDGT--LHFFVNGMTQGPAAWNVPPG--VYAVVDLYGQAAQATIV 684
Score = 41.6 bits (96), Expect = 8e-04
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 25 RFHRVHGANIRVDPSGTRATRVE---SFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHL 81
RFH++HG+N + G A R F + S L G++F + I++ W G +
Sbjct: 718 RFHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSI 777
Query: 82 RLGLTALDPASL 93
G+TA+ P L
Sbjct: 778 EAGVTAIRPEDL 789
Score = 40.0 bits (92), Expect = 0.002
Identities = 16/39 (41%), Positives = 24/39 (61%)
Query: 203 DMHIIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVRL 241
D+H ING+D G + GLP + +YAVVD++ V +
Sbjct: 843 DLHYFINGQDQGAACSGLPPGKEVYAVVDLYGQCVQVSI 881
Score = 39.3 bits (90), Expect = 0.004
Identities = 23/73 (31%), Positives = 30/73 (41%)
Query: 21 PPPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGH 80
P F HG NI + ATRV S+ G+ +PL P + V I+ W
Sbjct: 1129 PTTLEFLENHGKNILLSNGNRTATRVASYNQGIVVINQPLVPQLLVQVRIDFLNRQWTSS 1188
Query: 81 LRLGLTALDPASL 93
L LG+ P L
Sbjct: 1189 LVLGVITCAPERL 1201
Score = 37.4 bits (85), Expect = 0.015
Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
Query: 26 FHRVHGANIRVDPSGTRATR---VESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLR 82
FH G I++ + A R ++ F +GV + PL ++F + I++ W G +
Sbjct: 320 FHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRIDKLVDKWSGSIE 379
Query: 83 LGLTALDPASL 93
+G+T +P SL
Sbjct: 380 IGVTTHNPNSL 390
Score = 36.6 bits (83), Expect = 0.026
Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Query: 191 GVLFCPRPDGTADMHIIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVRLVQLEYGLPS 250
G + R D + +H+ +NG D G + +P QP +A+VD++ + V +V E G S
Sbjct: 1243 GTILGLRLDSSGGLHLHVNGVDQGVAVPDVP--QPCHALVDLYGQCEQVTIVNPEPGAAS 1300
>gi|53829368 neuralized homolog 4 isoform 2 [Homo sapiens]
Length = 1560
Score = 87.0 bits (214), Expect = 2e-17
Identities = 68/224 (30%), Positives = 99/224 (44%), Gaps = 60/224 (26%)
Query: 25 RFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLRLG 84
RFH G N+ ++ GTRA R +AHG+ FS + L +VF V++EE + W G LRLG
Sbjct: 913 RFHSTCGKNVTLEEDGTRAVRAAGYAHGLVFSTKELRAEEVFEVKVEELDEKWAGSLRLG 972
Query: 85 LTALDPASLAPVPEFSLPDLVNLGHTWVFAITRHHNRVPREGRPEAEAAAPSRPPTLLVE 144
LT L P + P A P PP+L
Sbjct: 973 LTTLAPGEMG---------------------------------PGAGGGGPGLPPSL--- 996
Query: 145 PYLR------IEQFRIPRDRLVGRSRPGLYSHLLDQLYELNVLPPTARRSRLGVLFCPRP 198
P LR + + RD + R Y L++L SR+GV R
Sbjct: 997 PELRTKTTWMVSSCEVRRDGQLQRMN---YGRNLERL---------GVGSRVGV----RR 1040
Query: 199 DGTADMHIIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVRLV 242
MHI+++GEDMGP+A G+ A+ ++AV+D++ + V +V
Sbjct: 1041 GADDTMHILVDGEDMGPAATGI--AKNVWAVLDLYGPVRGVSIV 1082
Score = 56.6 bits (135), Expect = 2e-08
Identities = 55/201 (27%), Positives = 80/201 (39%), Gaps = 58/201 (28%)
Query: 47 ESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLRLGLTALDPASLAPVPEFSLPDLVN 106
+ F HG+ SREPL G+VF V I+ K W G + +G+TALDP+ L +F
Sbjct: 68 QEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVL----DFPSSATGL 123
Query: 107 LGHTWVFAITRHHNRVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPG 166
G +WV + + RD GRS
Sbjct: 124 KGGSWV------------------------------------VSGCSVLRD---GRSVLE 144
Query: 167 LYSHLLDQLYELNVLPPTARRSRLGVLFCPRPDGTADMHIIINGEDMGPSARGLPAAQPL 226
Y LDQL E R+GV ++ + +NG D G +A GLP +
Sbjct: 145 EYGQDLDQLGE---------GDRVGV----ERTVAGELRLWVNGRDCGVAATGLPPR--V 189
Query: 227 YAVVDVFASTKSVRLVQLEYG 247
+AVVD++ + ++ E G
Sbjct: 190 WAVVDLYGKCTQITVLPPEPG 210
Score = 50.8 bits (120), Expect = 1e-06
Identities = 62/228 (27%), Positives = 85/228 (37%), Gaps = 65/228 (28%)
Query: 20 EPPPTRFHRVHGANIRVDPSGTRATR---VESFAHGVCFSREPLAPGQVFLVEIEEKELG 76
EP FH G + G A R + F HGV S L G+VF V I++
Sbjct: 517 EPERLLFHPNCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDK 576
Query: 77 WCGHLRLGLTALDPASLAPVPEFSLPD-LVNL-GHTWVFAITRHHNRVPREGRPEAEAAA 134
W G + +G+T +PA L LP + NL TW+ N V G
Sbjct: 577 WAGSIEIGVTTHNPAYL------QLPSTMTNLRSGTWMMT----GNGVMHNG-------- 618
Query: 135 PSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYSHLLDQLYELNVLPPTARRSRLGVLF 194
T+L E Y H LD+L +GV+
Sbjct: 619 ----TTILDE-----------------------YGHNLDRL---------KAGDTVGVV- 641
Query: 195 CPRPDGTADMHIIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVRLV 242
R DGT +H +NG GP+A +P +YAVVD++ +V
Sbjct: 642 -RREDGT--LHFFVNGMTQGPAAWNVPPG--VYAVVDLYGQAAQATIV 684
Score = 41.6 bits (96), Expect = 8e-04
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 25 RFHRVHGANIRVDPSGTRATRVE---SFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHL 81
RFH++HG+N + G A R F + S L G++F + I++ W G +
Sbjct: 718 RFHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSI 777
Query: 82 RLGLTALDPASL 93
G+TA+ P L
Sbjct: 778 EAGVTAIRPEDL 789
Score = 39.3 bits (90), Expect = 0.004
Identities = 23/73 (31%), Positives = 30/73 (41%)
Query: 21 PPPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGH 80
P F HG NI + ATRV S+ G+ +PL P + V I+ W
Sbjct: 1127 PTTLEFLENHGKNILLSNGNRTATRVASYNQGIVVINQPLVPQLLVQVRIDFLNRQWTSS 1186
Query: 81 LRLGLTALDPASL 93
L LG+ P L
Sbjct: 1187 LVLGVITCAPERL 1199
Score = 37.4 bits (85), Expect = 0.015
Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
Query: 26 FHRVHGANIRVDPSGTRATR---VESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLR 82
FH G I++ + A R ++ F +GV + PL ++F + I++ W G +
Sbjct: 320 FHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRIDKLVDKWSGSIE 379
Query: 83 LGLTALDPASL 93
+G+T +P SL
Sbjct: 380 IGVTTHNPNSL 390
Score = 36.6 bits (83), Expect = 0.026
Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Query: 191 GVLFCPRPDGTADMHIIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVRLVQLEYGLPS 250
G + R D + +H+ +NG D G + +P QP +A+VD++ + V +V E G S
Sbjct: 1241 GTILGLRLDSSGGLHLHVNGVDQGVAVPDVP--QPCHALVDLYGQCEQVTIVNPEPGAAS 1298
Score = 34.7 bits (78), Expect = 0.098
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Query: 203 DMHIIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVRL 241
D+H ING+D G + GLP +YAVVD++ V +
Sbjct: 843 DLHYFINGQDQGAACSGLP--PEVYAVVDLYGQCVQVSI 879
>gi|217416388 neuralized homolog 1B [Homo sapiens]
Length = 555
Score = 62.8 bits (151), Expect = 3e-10
Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Query: 25 RFH-RVHGANIRVDPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLRL 83
RFH + G N+R+D RATR SF +GV F++ P+ + + + GW G LR
Sbjct: 40 RFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRF 99
Query: 84 GLTALDPA--SLAPVPEFSLPDLVNLGHTWVFAI 115
G TA DP+ S +P+++ PDLV W A+
Sbjct: 100 GFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKAL 133
Score = 40.8 bits (94), Expect = 0.001
Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 12/109 (11%)
Query: 17 ERPEPPPT--------RFHRVHGANIRV--DPSGTRATRVESFAHGVCFSREPLAPGQVF 66
ERP P + RFH G ++ + D A R + + FS PL PG+
Sbjct: 265 ERPRPASSPALLEADLRFHATRGPDVSLSADRKVACAPRPDG-GRTLVFSERPLRPGESL 323
Query: 67 LVEIEEKELGWCGHLRLGLTALDPASLAPVPEFSLPD-LVNLGHTWVFA 114
VE+ L G L G+T+ DP L P + PD L++ WV A
Sbjct: 324 FVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPDALLDRKEYWVVA 372
>gi|223278368 neuralized-like [Homo sapiens]
Length = 574
Score = 56.6 bits (135), Expect = 2e-08
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Query: 23 PTRFH-RVHGANIRVDPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHL 81
P FH G+ I +D S R SF + + FS P+ + ++I +K+ W G L
Sbjct: 62 PLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGAL 121
Query: 82 RLGLTALDPASLAP--VPEFSLPDLVNLGHTWVFAI 115
RLG T+ DP+ + P +P+++ PDLV+ W A+
Sbjct: 122 RLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKAL 157
Score = 31.6 bits (70), Expect = 0.83
Identities = 19/53 (35%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Query: 219 GLPAAQPLYAVVDVFASTKSVRLVQLEYGLPS-LQTLCRLVIQRSMVHRLAID 270
G+ A PL+A+VDV+ T+ V+L+ E LP L+ ++R + R A D
Sbjct: 193 GVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLRREADD 245
Score = 30.8 bits (68), Expect = 1.4
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 11/94 (11%)
Query: 25 RFHRVH-GANIRVDPSGTRATRVESFAHG-----VCFSREPLAPGQVFLVEIEEKELGWC 78
RFH + GA++R+ T A RVE HG + F+ P+ + V++
Sbjct: 295 RFHALRAGAHVRILDEQTVA-RVE---HGRDERALVFTSRPVRVAETIFVKVTRSGGARP 350
Query: 79 GHLRLGLTALDPASLAPVP-EFSLPDLVNLGHTW 111
G L G+T DP +L P FS LV+ W
Sbjct: 351 GALSFGVTTCDPGTLRPADLPFSPEALVDRKEFW 384
>gi|195976771 cytokine-inducible SH2-containing protein isoform 1
[Homo sapiens]
Length = 275
Score = 33.1 bits (74), Expect = 0.29
Identities = 27/73 (36%), Positives = 33/73 (45%), Gaps = 16/73 (21%)
Query: 215 PSARGLPAAQPLYAV----VDVFASTKSVRLVQLEYGLPSLQTLCRLVIQRSMVHRLAID 270
PS LPA P AV V F S R SLQ LCRLVI R + +D
Sbjct: 209 PSDPALPAPPPATAVHLKLVQPFVRRSSAR---------SLQHLCRLVINRLVAD---VD 256
Query: 271 GLHLPKELKDFCK 283
L LP+ + D+ +
Sbjct: 257 CLPLPRRMADYLR 269
>gi|21614507 cytokine-inducible SH2-containing protein isoform 2
[Homo sapiens]
Length = 258
Score = 33.1 bits (74), Expect = 0.29
Identities = 27/73 (36%), Positives = 33/73 (45%), Gaps = 16/73 (21%)
Query: 215 PSARGLPAAQPLYAV----VDVFASTKSVRLVQLEYGLPSLQTLCRLVIQRSMVHRLAID 270
PS LPA P AV V F S R SLQ LCRLVI R + +D
Sbjct: 192 PSDPALPAPPPATAVHLKLVQPFVRRSSAR---------SLQHLCRLVINRLVAD---VD 239
Query: 271 GLHLPKELKDFCK 283
L LP+ + D+ +
Sbjct: 240 CLPLPRRMADYLR 252
>gi|18254474 ankyrin repeat and SOCS box-containing protein 11
isoform a [Homo sapiens]
Length = 323
Score = 32.7 bits (73), Expect = 0.37
Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 228 AVVDVFASTKSV-RLVQLEYGLPSLQTLCRLVIQRSM--VHRLAIDGLHLPKELKDFCKY 284
+ +D+ A SV + + L G P+L LCRL +++ + AI LHLP+ L+ F Y
Sbjct: 263 SALDLAAPKSSVEQALLLREGPPALSQLCRLCVRKCLGRACHQAIHKLHLPEPLERFLLY 322
Query: 285 E 285
+
Sbjct: 323 Q 323
>gi|60218887 ankyrin repeat and SOCS box-containing protein 11
isoform b [Homo sapiens]
Length = 302
Score = 32.7 bits (73), Expect = 0.37
Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 228 AVVDVFASTKSV-RLVQLEYGLPSLQTLCRLVIQRSM--VHRLAIDGLHLPKELKDFCKY 284
+ +D+ A SV + + L G P+L LCRL +++ + AI LHLP+ L+ F Y
Sbjct: 242 SALDLAAPKSSVEQALLLREGPPALSQLCRLCVRKCLGRACHQAIHKLHLPEPLERFLLY 301
Query: 285 E 285
+
Sbjct: 302 Q 302
>gi|39930571 leucine rich repeat containing 56 [Homo sapiens]
Length = 542
Score = 32.0 bits (71), Expect = 0.64
Identities = 32/111 (28%), Positives = 42/111 (37%), Gaps = 12/111 (10%)
Query: 121 RVPREGRPEAEAAAPSRPPTLLVEPYLRIEQFRI------PRDRLVGRSRPGLYSHLLDQ 174
RVP E +AE PS PP+L EP Q + PR R G S P + L +
Sbjct: 416 RVPEEQVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGSSSPRWSTDLQSR 475
Query: 175 LYELNVLPPTARRSRLGVLFCPRPDGTADMHIIINGEDMGPSARGLPAAQP 225
L VL GV P + + + P A+G P +P
Sbjct: 476 GRRLRVLGSWGPGLGDGVAAVP------VLRALEVASRLSPRAQGCPGPKP 520
>gi|21618354 suppressor of cytokine signaling 5 [Homo sapiens]
Length = 536
Score = 31.6 bits (70), Expect = 0.83
Identities = 18/34 (52%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 250 SLQTLCRLVIQRSMVHRLAIDGLHLPKELKDFCK 283
SLQ +CR VI R + IDGL LP L+DF K
Sbjct: 483 SLQYICRAVICRCTTYD-GIDGLPLPSMLQDFLK 515
>gi|7662240 suppressor of cytokine signaling 5 [Homo sapiens]
Length = 536
Score = 31.6 bits (70), Expect = 0.83
Identities = 18/34 (52%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 250 SLQTLCRLVIQRSMVHRLAIDGLHLPKELKDFCK 283
SLQ +CR VI R + IDGL LP L+DF K
Sbjct: 483 SLQYICRAVICRCTTYD-GIDGLPLPSMLQDFLK 515
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 31.2 bits (69), Expect = 1.1
Identities = 37/172 (21%), Positives = 63/172 (36%), Gaps = 12/172 (6%)
Query: 3 AASEPVDSGALWGLERPEP---PPTRFHRVHGANIRVDPSGTRATRVESFAHGVCFSREP 59
+A +P ++ L RP+P PP H +N++++ R ESF + + ++
Sbjct: 3096 SAWKPDETAPQSSLRRPDPGRLPPAASEEAHTSNVKMEKLYLHYLRAESFRKALIYQKKY 3155
Query: 60 LAPGQVFLVEIEEKELGWCGHLRLGLTALD-PASLAPVPEFSLPDLVNLGHTWVFAITRH 118
L + E++ L HL + + + + P F V + + + +
Sbjct: 3156 LLLLIGGFQDSEQETLSMIAHLGVFPSKAERKITSRPFTRFRTAVRVVIAILRLRFLVKK 3215
Query: 119 HNRVPREG--------RPEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGR 162
V R+G RP A P PP P R RD GR
Sbjct: 3216 WQEVDRKGALAQGKAPRPGPRARQPQSPPRTRESPPTRDVPSGHTRDPARGR 3267
>gi|46559761 PDZ domain containing 4 [Homo sapiens]
Length = 769
Score = 31.2 bits (69), Expect = 1.1
Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 4/75 (5%)
Query: 135 PSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYSHLLDQL-YELNVLPPTARRSRLGVL 193
P PP +++EP ++ P + + G + + LD+L YE L ++ R +LG++
Sbjct: 89 PPTPPMVILEPPPISHEYYDPAEFMEGGPQE---ADRLDELEYEEVELYKSSHRDKLGLM 145
Query: 194 FCPRPDGTADMHIII 208
C R D D+ I +
Sbjct: 146 VCYRTDDEEDLGIYV 160
>gi|4507263 suppressor of cytokine signaling-2 [Homo sapiens]
Length = 198
Score = 30.4 bits (67), Expect = 1.9
Identities = 18/33 (54%), Positives = 20/33 (60%), Gaps = 3/33 (9%)
Query: 249 PSLQTLCRLVIQRSMVHRLAIDGLHLPKELKDF 281
PSLQ LCRL I + AI GL LP LKD+
Sbjct: 161 PSLQHLCRLTINKCTG---AIWGLPLPTRLKDY 190
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 29.3 bits (64), Expect = 4.1
Identities = 14/50 (28%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Query: 165 PGLYS-HLLDQLYELNVLPPTARRSRLGVLFCPRPDGTADMHIIINGEDM 213
PGL + H+ +L LN+L + + + P P ++H+ I+ ED+
Sbjct: 972 PGLTTEHICSELRNLNILKNVSAEYSIYIACEPSPSANNEIHVAISAEDI 1021
>gi|239754042 PREDICTED: similar to hCG1646049 [Homo sapiens]
Length = 346
Score = 29.3 bits (64), Expect = 4.1
Identities = 22/54 (40%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 12 ALWGLERPEPPPTRFHRVHGANIRVDPSGTR--ATRVESFAHGVCFSREP-LAP 62
ALW R PPT F R P TR A R+ES G C P LAP
Sbjct: 229 ALWRSRRAPLPPTEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAP 282
>gi|239748572 PREDICTED: similar to hCG1646049 [Homo sapiens]
Length = 346
Score = 29.3 bits (64), Expect = 4.1
Identities = 22/54 (40%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 12 ALWGLERPEPPPTRFHRVHGANIRVDPSGTR--ATRVESFAHGVCFSREP-LAP 62
ALW R PPT F R P TR A R+ES G C P LAP
Sbjct: 229 ALWRSRRAPLPPTEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAP 282
>gi|169167670 PREDICTED: similar to hCG1646049 [Homo sapiens]
Length = 346
Score = 29.3 bits (64), Expect = 4.1
Identities = 22/54 (40%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 12 ALWGLERPEPPPTRFHRVHGANIRVDPSGTR--ATRVESFAHGVCFSREP-LAP 62
ALW R PPT F R P TR A R+ES G C P LAP
Sbjct: 229 ALWRSRRAPLPPTEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAP 282
>gi|217416354 sphingosine kinase type 1-interacting protein isoform 1
[Homo sapiens]
Length = 1700
Score = 29.3 bits (64), Expect = 4.1
Identities = 15/40 (37%), Positives = 22/40 (55%)
Query: 100 SLPDLVNLGHTWVFAITRHHNRVPREGRPEAEAAAPSRPP 139
++PD+V G T V A H + + PEAEA+ +R P
Sbjct: 1464 NIPDVVRGGDTAVSACQIHSDSLDTRDVPEAEASTEARAP 1503
>gi|217416352 sphingosine kinase type 1-interacting protein isoform 2
[Homo sapiens]
Length = 1671
Score = 29.3 bits (64), Expect = 4.1
Identities = 15/40 (37%), Positives = 22/40 (55%)
Query: 100 SLPDLVNLGHTWVFAITRHHNRVPREGRPEAEAAAPSRPP 139
++PD+V G T V A H + + PEAEA+ +R P
Sbjct: 1464 NIPDVVRGGDTAVSACQIHSDSLDTRDVPEAEASTEARAP 1503
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 28.9 bits (63), Expect = 5.4
Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Query: 248 LPSLQTLCRLVIQRSMVHRLAIDGLHLPKELKDFCKY 284
+PSLQ LCR+ I+R M + + L +P +L +F Y
Sbjct: 384 VPSLQHLCRMSIRRVMPTQ-EVQELPIPSKLLEFLSY 419
>gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo
sapiens]
Length = 275
Score = 28.9 bits (63), Expect = 5.4
Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Query: 248 LPSLQTLCRLVIQRSMVHRLAIDGLHLPKELKDFCKY 284
+PSLQ LCR+ I+R M + + L +P +L +F Y
Sbjct: 238 VPSLQHLCRMSIRRVMPTQ-EVQELPIPSKLLEFLSY 273
>gi|193794843 BEN domain containing 2 [Homo sapiens]
Length = 799
Score = 28.5 bits (62), Expect = 7.0
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 7/67 (10%)
Query: 79 GHLRLGLTALDPASLAPVPEF-----SLPDLVNLGHTWVFAITRHHN--RVPREGRPEAE 131
G+L+ GL ALDP ++ + EF + DL G W +T ++ R R AE
Sbjct: 710 GNLKHGLCALDPNKISALREFLQENYPICDLSENGRDWKSCVTSINSGIRSLRHDVRRAE 769
Query: 132 AAAPSRP 138
A + S P
Sbjct: 770 ARSQSLP 776
>gi|212286172 RNA polymerase I polypeptide B isoform 2 [Homo
sapiens]
Length = 1079
Score = 28.1 bits (61), Expect = 9.2
Identities = 11/28 (39%), Positives = 20/28 (71%)
Query: 56 SREPLAPGQVFLVEIEEKELGWCGHLRL 83
++E L PGQ+FL+ ++EK GW +++
Sbjct: 315 NQEVLTPGQLFLMFLKEKLEGWLVSIKI 342
>gi|33469941 RNA polymerase I polypeptide B isoform 1 [Homo sapiens]
Length = 1135
Score = 28.1 bits (61), Expect = 9.2
Identities = 11/28 (39%), Positives = 20/28 (71%)
Query: 56 SREPLAPGQVFLVEIEEKELGWCGHLRL 83
++E L PGQ+FL+ ++EK GW +++
Sbjct: 371 NQEVLTPGQLFLMFLKEKLEGWLVSIKI 398
>gi|194578891 abhydrolase domain-containing protein 1 [Homo sapiens]
Length = 405
Score = 28.1 bits (61), Expect = 9.2
Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Query: 206 IIINGEDMGPSARGLPAAQPLYAVVDVFASTKSVR--LVQLEYGLPSLQTLCRLVIQRSM 263
+++N A GL AA L A D F +T+S+ L L + P LC+LV +
Sbjct: 208 LVLNHLAQARQAAGLVAALTLSACWDSFETTRSLETPLNSLLFNQPLTAGLCQLVERNRK 267
Query: 264 VHRLAID 270
V +D
Sbjct: 268 VIEKVVD 274
>gi|46560555 transmembrane protein 132E [Homo sapiens]
Length = 984
Score = 28.1 bits (61), Expect = 9.2
Identities = 17/44 (38%), Positives = 23/44 (52%)
Query: 84 GLTALDPASLAPVPEFSLPDLVNLGHTWVFAITRHHNRVPREGR 127
GLT L+ A + F L LV L + VF + H R+P EG+
Sbjct: 793 GLTDLEIGMYALLGVFCLAILVFLINCIVFVLRYRHKRIPPEGQ 836
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.140 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,174,119
Number of Sequences: 37866
Number of extensions: 671591
Number of successful extensions: 1567
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1521
Number of HSP's gapped (non-prelim): 57
length of query: 285
length of database: 18,247,518
effective HSP length: 101
effective length of query: 184
effective length of database: 14,423,052
effective search space: 2653841568
effective search space used: 2653841568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.