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Search of human proteins with 17978469
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17978469 cyclin T2 isoform b [Homo sapiens]
(730 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17978469 cyclin T2 isoform b [Homo sapiens] 1472 0.0
gi|4502629 cyclin T2 isoform a [Homo sapiens] 1293 0.0
gi|17978466 cyclin T1 [Homo sapiens] 551 e-156
gi|150417989 cyclin K isoform 1 [Homo sapiens] 135 2e-31
gi|38176158 cyclin K isoform 2 [Homo sapiens] 135 2e-31
gi|88758580 cyclin L2 isoform A [Homo sapiens] 101 2e-21
gi|9945320 cyclin L1 [Homo sapiens] 100 4e-21
gi|196049382 family with sequence similarity 58, member A isofor... 85 3e-16
gi|221554516 cyclin L2 isoform C [Homo sapiens] 79 2e-14
gi|221554518 cyclin L2 isoform D [Homo sapiens] 78 3e-14
gi|88758578 cyclin L2 isoform B [Homo sapiens] 78 3e-14
gi|157502165 family with sequence similarity 58 member B [Homo s... 78 3e-14
gi|196049384 family with sequence similarity 58, member A isofor... 75 2e-13
gi|61676091 cyclin C isoform a [Homo sapiens] 74 5e-13
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 59 2e-08
gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regula... 55 3e-07
gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regula... 55 3e-07
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 54 4e-07
gi|57864582 hornerin [Homo sapiens] 53 9e-07
gi|60097902 filaggrin [Homo sapiens] 52 1e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 51 3e-06
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 49 2e-05
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 49 2e-05
gi|50962882 G patch domain containing 8 [Homo sapiens] 49 2e-05
gi|113415504 PREDICTED: similar to ribonucleic acid binding prot... 46 1e-04
gi|169166499 PREDICTED: similar to ribonucleic acid binding prot... 46 1e-04
gi|113415498 PREDICTED: similar to ribonucleic acid binding prot... 46 1e-04
gi|88973230 PREDICTED: similar to ribonucleic acid binding prote... 46 1e-04
gi|28559039 mediator complex subunit 1 [Homo sapiens] 46 1e-04
gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens] 46 1e-04
>gi|17978469 cyclin T2 isoform b [Homo sapiens]
Length = 730
Score = 1472 bits (3810), Expect = 0.0
Identities = 730/730 (100%), Positives = 730/730 (100%)
Query: 1 MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINT 60
MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINT
Sbjct: 1 MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINT 60
Query: 61 AIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDT 120
AIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDT
Sbjct: 61 AIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDT 120
Query: 121 KCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNS 180
KCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNS
Sbjct: 121 KCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNS 180
Query: 181 LHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEF 240
LHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEF
Sbjct: 181 LHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEF 240
Query: 241 LQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPS 300
LQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPS
Sbjct: 241 LQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPS 300
Query: 301 FQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSART 360
FQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSART
Sbjct: 301 FQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSART 360
Query: 361 EQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHH 420
EQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHH
Sbjct: 361 EQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHH 420
Query: 421 GPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTS 480
GPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTS
Sbjct: 421 GPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTS 480
Query: 481 PIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE 540
PIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE
Sbjct: 481 PIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE 540
Query: 541 GSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLR 600
GSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLR
Sbjct: 541 GSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLR 600
Query: 601 SPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNS 660
SPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNS
Sbjct: 601 SPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNS 660
Query: 661 VFNHPLPPPPPVTYQVGYGHLSTLVKLDKKPVETNGPDANHEYSTSSQHMDYKDTFDMLD 720
VFNHPLPPPPPVTYQVGYGHLSTLVKLDKKPVETNGPDANHEYSTSSQHMDYKDTFDMLD
Sbjct: 661 VFNHPLPPPPPVTYQVGYGHLSTLVKLDKKPVETNGPDANHEYSTSSQHMDYKDTFDMLD 720
Query: 721 SLLSAQGMNM 730
SLLSAQGMNM
Sbjct: 721 SLLSAQGMNM 730
>gi|4502629 cyclin T2 isoform a [Homo sapiens]
Length = 663
Score = 1293 bits (3347), Expect = 0.0
Identities = 643/647 (99%), Positives = 644/647 (99%)
Query: 1 MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINT 60
MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINT
Sbjct: 1 MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINT 60
Query: 61 AIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDT 120
AIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDT
Sbjct: 61 AIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDT 120
Query: 121 KCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNS 180
KCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNS
Sbjct: 121 KCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNS 180
Query: 181 LHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEF 240
LHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEF
Sbjct: 181 LHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEF 240
Query: 241 LQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPS 300
LQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPS
Sbjct: 241 LQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPS 300
Query: 301 FQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSART 360
FQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSART
Sbjct: 301 FQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSART 360
Query: 361 EQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHH 420
EQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHH
Sbjct: 361 EQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHH 420
Query: 421 GPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTS 480
GPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTS
Sbjct: 421 GPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTS 480
Query: 481 PIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE 540
PIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE
Sbjct: 481 PIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE 540
Query: 541 GSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLR 600
GSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLR
Sbjct: 541 GSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLR 600
Query: 601 SPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSS 647
SPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSG +S
Sbjct: 601 SPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGGLRTS 647
>gi|17978466 cyclin T1 [Homo sapiens]
Length = 726
Score = 551 bits (1419), Expect = e-156
Identities = 345/740 (46%), Positives = 443/740 (59%), Gaps = 94/740 (12%)
Query: 8 SSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHR 67
+ RW+FTREQLEN+PSRR GV+ DKELS RQQAANL+Q+MGQRLNVSQLTINTAIVYMHR
Sbjct: 9 NKRWYFTREQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHR 68
Query: 68 FYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQ 127
FYM SFT+F N ++ ALFLAAKVEEQ +KLEHVIKVAH CLHP E L DT+ +AYLQ
Sbjct: 69 FYMIQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQ 128
Query: 128 QTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFC 187
Q Q+LVILE+I+LQTLGFE+TI+HPHT VVKCTQLVRASKDLAQTSYFMATNSLHLTTF
Sbjct: 129 QVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFS 188
Query: 188 LQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKT 247
LQY P V+ACVCIHLACKWSNWEIPVSTDGKHWWEYVD TVTLELLDELTHEFLQILEKT
Sbjct: 189 LQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKT 248
Query: 248 PNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPSFQKPSTS 307
PNRLK+I NWRA +AA+K K D + ++ +++ S T + S +TS
Sbjct: 249 PNRLKRIWNWRACEAAKKTKADDRGTDEKTSEQTILNMISQSSSDTTIAGLMSMSTSTTS 308
Query: 308 AFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQK 367
A P+ +P++ +S NL TS + + W Q S + E +
Sbjct: 309 AVPS-LPVS--------EESSSNL---------TSVEMLPGKRWLSSQPSFKLEPTQGHR 350
Query: 368 QETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTP 427
+L+ +G+ H + ++ + Q+ K+ S
Sbjct: 351 TSENLA----------------LTGVDHSLPQDGSNAFISQKQNSKSVPS---------- 384
Query: 428 GIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIP 487
K+SL +YR K E + + A V+ Q+ S S + +K+P
Sbjct: 385 ----AKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSHHDSHSSVILKMP 440
Query: 488 I---ANTEKYMADKKEKSGSLKLRIPIPPTDKSASK--EELKMKIKV-SSSERHSSSDEG 541
I N E+ +K +K+ +LK+RIP+ DK+AS EE+KM+IKV +++++H+S ++
Sbjct: 441 IEGSENPERPFLEKADKT-ALKMRIPVAGGDKAASSKPEEIKMRIKVHAAADKHNSVEDS 499
Query: 542 SGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSS---------SGGSKHSAD 592
K SR+HKEKHK HPS+ HH +H HSH HS S G KHS+
Sbjct: 500 VTK--------SREHKEKHKTHPSNHHHHHNH-HSHKHSHSQLPVGTGNKRPGDPKHSSQ 550
Query: 593 GIPPTVLRSPVGLSSDGISSSSSSSRKR---LHVNDASHNHHSKMSKSSKSSG-SSSSSS 648
+ LSS SSSSS+RKR A +H +K++KS+KSS + S S
Sbjct: 551 --TSNLAHKTYSLSSS--FSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSSSLNFSFPS 606
Query: 649 SSVKQYISSHNSVFNHPLPPPPPVTYQVGYGHLSTLVKLDKKPVETNGPDANHEYSTSSQ 708
+ H+S + P +V + KLDK P NG ++Q
Sbjct: 607 LPTMGQMPGHSSDTSGLSFSQPSCKTRVPHS------KLDKGPTGANG-------HNTTQ 653
Query: 709 HMDYKDTFDMLDSLLSAQGM 728
+DY+DT +ML SLLSAQG+
Sbjct: 654 TIDYQDTVNMLHSLLSAQGV 673
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 135 bits (339), Expect = 2e-31
Identities = 80/258 (31%), Positives = 142/258 (55%), Gaps = 21/258 (8%)
Query: 11 WFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYM 70
W++ ++ L +TPS+ G++ E R++ A I ++G RL + T+ T I+Y HRFYM
Sbjct: 24 WYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYM 83
Query: 71 HHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQ-T 129
HSF +F + + + LFLA KVEE +K + +IK A + L+ D + +
Sbjct: 84 FHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLN------DVQFGQFGDDPK 137
Query: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMA---TNSLHLTTF 186
+E+++LE I+LQT+ F++ +EHP+ ++K + ++ K+ Q MA N TT
Sbjct: 138 EEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTL 197
Query: 187 CLQYKPTVIACVCIHLACKWSNWEIPVSTDG---KHWWEYVDPTVTLELLDELTHEFL-- 241
LQ++P +IA ++LA + +EI T + WWE V +++L+++ H+ L
Sbjct: 198 SLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDL 257
Query: 242 ------QILEKTPNRLKK 253
Q+ TP++L++
Sbjct: 258 YSQGKQQMPHHTPHQLQQ 275
>gi|38176158 cyclin K isoform 2 [Homo sapiens]
Length = 354
Score = 135 bits (339), Expect = 2e-31
Identities = 80/258 (31%), Positives = 142/258 (55%), Gaps = 21/258 (8%)
Query: 11 WFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYM 70
W++ ++ L +TPS+ G++ E R++ A I ++G RL + T+ T I+Y HRFYM
Sbjct: 24 WYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYM 83
Query: 71 HHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQ-T 129
HSF +F + + + LFLA KVEE +K + +IK A + L+ D + +
Sbjct: 84 FHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLN------DVQFGQFGDDPK 137
Query: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMA---TNSLHLTTF 186
+E+++LE I+LQT+ F++ +EHP+ ++K + ++ K+ Q MA N TT
Sbjct: 138 EEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTL 197
Query: 187 CLQYKPTVIACVCIHLACKWSNWEIPVSTDG---KHWWEYVDPTVTLELLDELTHEFL-- 241
LQ++P +IA ++LA + +EI T + WWE V +++L+++ H+ L
Sbjct: 198 SLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDL 257
Query: 242 ------QILEKTPNRLKK 253
Q+ TP++L++
Sbjct: 258 YSQGKQQMPHHTPHQLQQ 275
>gi|88758580 cyclin L2 isoform A [Homo sapiens]
Length = 520
Score = 101 bits (252), Expect = 2e-21
Identities = 97/374 (25%), Positives = 162/374 (43%), Gaps = 34/374 (9%)
Query: 16 EQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFT 75
++L TPS G++ D E R LIQ G L + Q+ + T V RF+ SF
Sbjct: 57 DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116
Query: 76 KFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLH------PLEPLLDTKCDAYLQQT 129
K + +S + LA+K+EE R++ VI V H P+ LLD Y+
Sbjct: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLD---QDYVNLK 173
Query: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKD--LAQTSYFMATNSLHLTTFC 187
+++ E +L+ LGF + ++HPH +V Q++ ++ L QTS+ +SL F
Sbjct: 174 NQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVF- 232
Query: 188 LQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKT 247
++++P IAC CI+LA + EIP+ + HW+ T +E+ L+IL+
Sbjct: 233 VRFQPESIACACIYLAAR--TLEIPL-PNRPHWFLLFGATE-----EEIQEICLKILQLY 284
Query: 248 PNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPSF-QKPST 306
+ + + RK ++ ++ L L + ++D +G P + P
Sbjct: 285 ARKKVDLTHLEGEVEKRKHAIEEAKAQARGL---LPGGTQVLDGTSGFSPAPKLVESPKE 341
Query: 307 SAFPAPVPLNSGNI-----SVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTE 361
P PL+ N + + ++ L G S S S Q + S
Sbjct: 342 GKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSY-----SRSPS 396
Query: 362 QLYSQKQETSLSGS 375
+ S K+ S SGS
Sbjct: 397 RSASPKRRKSDSGS 410
Score = 35.0 bits (79), Expect = 0.25
Identities = 37/141 (26%), Positives = 57/141 (40%), Gaps = 13/141 (9%)
Query: 519 SKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHS 578
S + K +++ + + S G K + S SR ++ + PS ++S K S
Sbjct: 351 SVKNTKRRLEGAKKAKADSPVNGLPKGRESRSR-SRSREQSYSRSPS---RSASPKRRKS 406
Query: 579 HSGSSSGGSK-----HSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSK 633
SGS+SGGSK S PP ++P G S SRK H S+
Sbjct: 407 DSGSTSGGSKSQSRSRSRSDSPPR--QAPRSAPYKG--SEIRGSRKSKDCKYPQKPHKSR 462
Query: 634 MSKSSKSSGSSSSSSSSVKQY 654
SS+S S + + +Y
Sbjct: 463 SRSSSRSRSRSRERADNPGKY 483
>gi|9945320 cyclin L1 [Homo sapiens]
Length = 526
Score = 100 bits (250), Expect = 4e-21
Identities = 74/243 (30%), Positives = 121/243 (49%), Gaps = 18/243 (7%)
Query: 16 EQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFT 75
E+L TPS + G++ E R LIQ G L + Q+ + T V HRF+ SF
Sbjct: 62 ERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFV 121
Query: 76 KFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLH------PLEPLLDTKCDAYLQQT 129
K + I++ + LA+K+EE R++ VI V H P +LD Y+
Sbjct: 122 KHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQN---YINTK 178
Query: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKD--LAQTSYFMATNSLHLTTFC 187
+++ E +L+ LGF + ++HPH +V Q++ ++ L QT++ +SL F
Sbjct: 179 NQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVF- 237
Query: 188 LQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQI-LEK 246
++++P IAC CI+LA + +IP+ T HW+ T E + E+ E L++ K
Sbjct: 238 VRFQPETIACACIYLAAR--ALQIPLPT-RPHWFLLFG--TTEEEIQEICIETLRLYTRK 292
Query: 247 TPN 249
PN
Sbjct: 293 KPN 295
Score = 33.9 bits (76), Expect = 0.55
Identities = 53/225 (23%), Positives = 81/225 (36%), Gaps = 22/225 (9%)
Query: 440 REKRKLETLDLDVRDHYIAAQVEQQHKQGQSQ----AASSSSVTSPIKMKIPIANTEKYM 495
R+K E L+ +V +A Q + +G + A S+ SP P + E
Sbjct: 291 RKKPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASK--PSSPREVKA 348
Query: 496 ADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHS--SSDEGSGKSKHSSPHIS 553
+K S ++K P + ASK K S R+S +S S S H
Sbjct: 349 EEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTP 408
Query: 554 RDHKEKHKEHPS---------SRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVG 604
R H + SR H+ S + H+H GS +KH+ D + +
Sbjct: 409 RRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNH-GSPHLKAKHTRDDLKSSNRHG--- 464
Query: 605 LSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSS 649
S S S S+ R H + A + H + + S S S
Sbjct: 465 -HKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERS 508
Score = 32.3 bits (72), Expect = 1.6
Identities = 22/65 (33%), Positives = 29/65 (44%), Gaps = 8/65 (12%)
Query: 529 VSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSR-HHTSSHKHSHS----HSGSS 583
+ SS RH + KS+ S SRDH + K+H R HH + S S H
Sbjct: 457 LKSSNRHGHKRK---KSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSKH 513
Query: 584 SGGSK 588
GGS+
Sbjct: 514 HGGSR 518
>gi|196049382 family with sequence similarity 58, member A isoform 1
[Homo sapiens]
Length = 248
Score = 84.7 bits (208), Expect = 3e-16
Identities = 54/216 (25%), Positives = 110/216 (50%), Gaps = 15/216 (6%)
Query: 39 QAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQAR 98
+ A I E G +L + + I TA H+F+ + ++ +I+ ++++LA KVEEQ
Sbjct: 29 RVARFIMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHL 88
Query: 99 KLEHVIKVAHACLHPL-EPL-LDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDV 156
+ +I V++ +P EPL LD++ + + +V E +ML+ L F+++ +HPH +
Sbjct: 89 RTRDIINVSNRYFNPSGEPLELDSR---FWELRDSIVQCELLMLRVLRFQVSFQHPHKYL 145
Query: 157 VKCTQLVR--------ASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSN 208
+ ++ +A T++ + +S H CL+++ IA ++LA +
Sbjct: 146 LHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYH-GALCLRFQAQHIAVAVLYLALQVYG 204
Query: 209 WEIPVSTDG-KHWWEYVDPTVTLELLDELTHEFLQI 243
E+P + K WW+ + +T ++D + + +QI
Sbjct: 205 VEVPAEVEAEKPWWQVFNDDLTKPIIDNIVSDLIQI 240
>gi|221554516 cyclin L2 isoform C [Homo sapiens]
Length = 236
Score = 78.6 bits (192), Expect = 2e-14
Identities = 52/174 (29%), Positives = 85/174 (48%), Gaps = 11/174 (6%)
Query: 16 EQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFT 75
++L TPS G++ D E R LIQ G L + Q+ + T V RF+ SF
Sbjct: 57 DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116
Query: 76 KFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLH------PLEPLLDTKCDAYLQQT 129
K + +S + LA+K+EE R++ VI V H P+ LLD Y+
Sbjct: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLD---QDYVNLK 173
Query: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKD--LAQTSYFMATNSL 181
+++ E +L+ LGF + ++HPH +V Q++ ++ L QTS+ + + L
Sbjct: 174 NQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWVASEDPL 227
>gi|221554518 cyclin L2 isoform D [Homo sapiens]
Length = 227
Score = 77.8 bits (190), Expect = 3e-14
Identities = 51/167 (30%), Positives = 82/167 (49%), Gaps = 11/167 (6%)
Query: 16 EQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFT 75
++L TPS G++ D E R LIQ G L + Q+ + T V RF+ SF
Sbjct: 57 DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116
Query: 76 KFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLH------PLEPLLDTKCDAYLQQT 129
K + +S + LA+K+EE R++ VI V H P+ LLD Y+
Sbjct: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLD---QDYVNLK 173
Query: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKD--LAQTSY 174
+++ E +L+ LGF + ++HPH +V Q++ ++ L QTS+
Sbjct: 174 NQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSW 220
>gi|88758578 cyclin L2 isoform B [Homo sapiens]
Length = 226
Score = 77.8 bits (190), Expect = 3e-14
Identities = 51/167 (30%), Positives = 82/167 (49%), Gaps = 11/167 (6%)
Query: 16 EQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFT 75
++L TPS G++ D E R LIQ G L + Q+ + T V RF+ SF
Sbjct: 57 DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116
Query: 76 KFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLH------PLEPLLDTKCDAYLQQT 129
K + +S + LA+K+EE R++ VI V H P+ LLD Y+
Sbjct: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLD---QDYVNLK 173
Query: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKD--LAQTSY 174
+++ E +L+ LGF + ++HPH +V Q++ ++ L QTS+
Sbjct: 174 NQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSW 220
>gi|157502165 family with sequence similarity 58 member B [Homo
sapiens]
Length = 252
Score = 77.8 bits (190), Expect = 3e-14
Identities = 57/218 (26%), Positives = 106/218 (48%), Gaps = 19/218 (8%)
Query: 39 QAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQAR 98
+ A I E G +L + + I TA +F+ F+ +I+ ++++LA KVEEQ
Sbjct: 33 RVARFIMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQPL 92
Query: 99 KLEHVIKVAHACLHP-LEPL-LDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPH--- 153
+I V++ +P EPL LD++ + +V E +ML+ L F+++ +HPH
Sbjct: 93 WAHDIISVSNRYFNPSSEPLGLDSR---LWELRDSIVQRELLMLRVLRFQVSFQHPHKYL 149
Query: 154 -------TDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKW 206
+ + C R +A T++ + +S H CL+++ IA V ++LA +
Sbjct: 150 LYYLVSLKNWLNCHSWQRT--PVAVTAWALLRDSYH-GGLCLRFQAQHIAVVVLYLALQV 206
Query: 207 SNWEIPVSTDG-KHWWEYVDPTVTLELLDELTHEFLQI 243
E+P + K WW+ +T ++D + + +QI
Sbjct: 207 YGVEVPAEVEAEKLWWQAFSDDLTKPIIDTIVSDLIQI 244
>gi|196049384 family with sequence similarity 58, member A isoform 2
[Homo sapiens]
Length = 228
Score = 75.5 bits (184), Expect = 2e-13
Identities = 50/195 (25%), Positives = 99/195 (50%), Gaps = 15/195 (7%)
Query: 39 QAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQAR 98
+ A I E G +L + + I TA H+F+ + ++ +I+ ++++LA KVEEQ
Sbjct: 29 RVARFIMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHL 88
Query: 99 KLEHVIKVAHACLHPL-EPL-LDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDV 156
+ +I V++ +P EPL LD++ + + +V E +ML+ L F+++ +HPH +
Sbjct: 89 RTRDIINVSNRYFNPSGEPLELDSR---FWELRDSIVQCELLMLRVLRFQVSFQHPHKYL 145
Query: 157 VKCTQLVR--------ASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSN 208
+ ++ +A T++ + +S H CL+++ IA ++LA +
Sbjct: 146 LHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYH-GALCLRFQAQHIAVAVLYLALQVYG 204
Query: 209 WEIPVSTDG-KHWWE 222
E+P + K WW+
Sbjct: 205 VEVPAEVEAEKPWWQ 219
>gi|61676091 cyclin C isoform a [Homo sapiens]
Length = 283
Score = 73.9 bits (180), Expect = 5e-13
Identities = 53/216 (24%), Positives = 98/216 (45%), Gaps = 26/216 (12%)
Query: 42 NLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEE------ 95
N+IQ +G+ L + Q I TA VY RFY +S + +++ T +FLA+KVEE
Sbjct: 46 NVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSN 105
Query: 96 --QARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPH 153
V+K + P E + + ++ E +L+ + + + HP+
Sbjct: 106 TRLIAAATSVLKTRFSYAFPKE---------FPYRMNHILECEFYLLELMDCCLIVYHPY 156
Query: 154 TDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPV 213
+++ Q + +D+ + N + T CL Y P +IA C+H+AC +
Sbjct: 157 RPLLQYVQDM-GQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVAC------VVQ 209
Query: 214 STDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPN 249
D + W + + +V +E + E+ L++ E+ N
Sbjct: 210 QKDARQW--FAELSVDMEKILEIIRVILKLYEQWKN 243
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 58.5 bits (140), Expect = 2e-08
Identities = 114/470 (24%), Positives = 168/470 (35%), Gaps = 79/470 (16%)
Query: 291 SVTGVPTNPSFQKPSTSAFPAPVPLNSGNISVQDSH--TSDNLSMLATGMPSTSYGLSSH 348
SV + NP +P T P+ L++ + DS T D L +G S H
Sbjct: 125 SVGNISHNPKMAQPRTEPMPS---LHAKSCGPPDSQHLTQDRLGQ-------EGFGSSHH 174
Query: 349 QEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQ 408
++ + D + E LS P ISL S + +S S +Q
Sbjct: 175 KKGDRRADGDHCASVTDSAPERELS-----------PLISLPSPV----PPLSPIHSNQQ 219
Query: 409 EYTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAA--------- 459
GSSK HG + + G P K D + ET +D +A
Sbjct: 220 TLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKET----PQDSLVAPAQPPSQTFP 275
Query: 460 -------QVEQQHK--------QGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGS 504
V Q K GQ QA S S P+ EK K+
Sbjct: 276 PPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKL 335
Query: 505 LKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISR-DHKEKHKEH 563
KL++P +++ S E ++ ++ HS + S+ S+ K +H
Sbjct: 336 TKLKMPSQSVEQTYSNEVHCVE-EILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQH 394
Query: 564 PSS------RHHTSSHKHSHSHSGSSS--GGSKHSADGIPPTVLRSPVGLSSDGISSSSS 615
SS ++ TSS HS+S G+SS +D ++P S SS+
Sbjct: 395 VSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPS---SSAPP 451
Query: 616 SSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSVFNHPLPPP-PPVTY 674
S+ + L AS + S S+S+ S SSS S S S N P P P PP T
Sbjct: 452 SAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTN 511
Query: 675 QVGYGHLSTLVKLDKKPVE---TNGPDANH-------EYSTSSQHMDYKD 714
+ + T V P E + P H + +TS +H + KD
Sbjct: 512 KWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKD 561
Score = 37.4 bits (85), Expect = 0.050
Identities = 105/514 (20%), Positives = 174/514 (33%), Gaps = 106/514 (20%)
Query: 280 SSLVQNSILVDSVTGVPTNPSFQKPSTSAFPA------PVPLNSGNISVQDSH-TSDNLS 332
SS++++ + + + + +KP +S+ P P P+ S + S +S TSD+ S
Sbjct: 420 SSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDS 479
Query: 333 MLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETS--LSGSQYNINFQQGPSISLH 390
++ S S S + P + E + K + L+ +GP S
Sbjct: 480 --SSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPR-STE 536
Query: 391 SGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDL 450
H K S S+ QE++ SK P S++ P+ + KR +
Sbjct: 537 PPRRHPESKGSSDSATSQEHSE----SKDPPPKSSSKA--PRAPPEAPHPGKRSCQ---- 586
Query: 451 DVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADK---------KEK 501
+ Q + Q Q + P+K + ++ +++
Sbjct: 587 ---------KSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQ 637
Query: 502 SGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKE-KH 560
+ K ++ ++A+ E K + SS ++ S + S P ++D+ E +
Sbjct: 638 TSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRT 697
Query: 561 KEHPSSRHHTSSHKHSHSHSGSSSGGSKHSA-------------------------DGIP 595
EH + T S HS SGS + G + + D P
Sbjct: 698 PEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPP 757
Query: 596 PTVLRSPVGL------------------------------SSDGISSSSSSSRKRLHVND 625
P L + L SS+ SS SSS + +
Sbjct: 758 PQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGE 817
Query: 626 ASH---NHHSKMSKSSKSSGSSSSSS----SSVKQYISSHNSVFNHPLPPPPPVTYQVGY 678
A N ++ K KS SSSSSS S K S S LPPPP
Sbjct: 818 AERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPP--VSSSSQ 875
Query: 679 GHLSTLVKLDKKPVETNGPD-ANHEYSTSSQHMD 711
+K ++ +T G D ST S H D
Sbjct: 876 KPAKPALKRSRREADTCGQDPPKSASSTKSNHKD 909
Score = 34.3 bits (77), Expect = 0.42
Identities = 55/231 (23%), Positives = 85/231 (36%), Gaps = 20/231 (8%)
Query: 483 KMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASK--EELKMKIKVSSSERHSSSDE 540
K+ P+ +T + + + L RIP PP S + E+ + S SSD
Sbjct: 747 KLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDS 806
Query: 541 GSGKSKHSSPHISRDHKEK----HKEHPS-SRHHTSSHKHSHSHSGSSSGGSKHSADGIP 595
S +K RD K KE S S +SSHK S S + +P
Sbjct: 807 SSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLP 866
Query: 596 PTVLRS-------PVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSS 648
P + S P S + + + + S++ S + K + G S SS
Sbjct: 867 PPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSS 926
Query: 649 SSVKQYISSHNSVFNHPLPPPPPVTYQVGYGHLSTLVKLDKKPVETNGPDA 699
S K SS ++ P+P P + G VK DK+ + + +A
Sbjct: 927 SEHKG--SSGDTANPFPVPSLPNGNSKPG----KPQVKFDKQQADLHMREA 971
>gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 2 [Homo sapiens]
Length = 754
Score = 54.7 bits (130), Expect = 3e-07
Identities = 34/103 (33%), Positives = 50/103 (48%), Gaps = 17/103 (16%)
Query: 551 HISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGI 610
H++ H H +S HH H H H H G + G++ P V SP
Sbjct: 581 HVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNR-----TRPRVYNSP-------- 627
Query: 611 SSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQ 653
++SSS++ + V H+HHS S SS ++ SS+SSSS+ Q
Sbjct: 628 -TNSSSTQDSMEV---GHSHHSMTSLSSSTTSSSTSSSSTGNQ 666
>gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 1 [Homo sapiens]
Length = 763
Score = 54.7 bits (130), Expect = 3e-07
Identities = 34/103 (33%), Positives = 50/103 (48%), Gaps = 17/103 (16%)
Query: 551 HISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGI 610
H++ H H +S HH H H H H G + G++ P V SP
Sbjct: 590 HVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNR-----TRPRVYNSP-------- 636
Query: 611 SSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQ 653
++SSS++ + V H+HHS S SS ++ SS+SSSS+ Q
Sbjct: 637 -TNSSSTQDSMEV---GHSHHSMTSLSSSTTSSSTSSSSTGNQ 675
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 54.3 bits (129), Expect = 4e-07
Identities = 47/147 (31%), Positives = 61/147 (41%), Gaps = 4/147 (2%)
Query: 514 TDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSH 573
+D S S + SS+ SSD S SK S D K + SS S
Sbjct: 596 SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS----DSS 651
Query: 574 KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSK 633
+S S S+S S S+D + S S+ SS SS S +D+S + S
Sbjct: 652 DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSD 711
Query: 634 MSKSSKSSGSSSSSSSSVKQYISSHNS 660
S SS SS S+SS S S SS +S
Sbjct: 712 SSDSSDSSNSNSSDSDSSNSSDSSDSS 738
Score = 53.9 bits (128), Expect = 5e-07
Identities = 77/334 (23%), Positives = 117/334 (35%), Gaps = 26/334 (7%)
Query: 317 SGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQ 376
+GN D+ SD+ + S S S+ + DS ++ S ++S S S
Sbjct: 529 NGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSS 588
Query: 377 YNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSL 436
+ + S S +S SD S K+ SSK S +
Sbjct: 589 DSSDSDS--SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS-------- 638
Query: 437 DKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMA 496
K ++ D + D + S +S SS +S +N+ +
Sbjct: 639 -------KSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD-SS 690
Query: 497 DKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDH 556
D + S S + +D +S S S +SSD S S SS +
Sbjct: 691 DSSDSSNSSESSDSSDSSDSDSSDS--------SDSSNSNSSDSDSSNSSDSSDSSNSSD 742
Query: 557 KEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSS 616
+ +S + S S+S S S S S+D + S SS+SS
Sbjct: 743 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD 802
Query: 617 SRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSS 650
S +D+S + S S SS SS SS SS SS
Sbjct: 803 SSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS 836
Score = 52.4 bits (124), Expect = 1e-06
Identities = 72/341 (21%), Positives = 118/341 (34%), Gaps = 5/341 (1%)
Query: 321 SVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNIN 380
S S +SD+ + + S S S + DS+ + ++ S S + N
Sbjct: 740 SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799
Query: 381 FQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYR 440
+ S S D S +SS + + SS S + D
Sbjct: 800 SSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS----SDSSDSSDSSDGSDSDS 855
Query: 441 EKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKY-MADKK 499
R + D D ++ S +S+SS +S +++ +D
Sbjct: 856 SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915
Query: 500 EKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEK 559
+ S S +D S S + SS+ +SSD + +S S +
Sbjct: 916 DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD 975
Query: 560 HKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRK 619
+ +S + S S S S S S S+D + + S+ SS+SS S
Sbjct: 976 SSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 1035
Query: 620 RLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNS 660
+D+S + S S S +S SS SS S SS +S
Sbjct: 1036 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1076
Score = 51.6 bits (122), Expect = 3e-06
Identities = 51/193 (26%), Positives = 76/193 (39%), Gaps = 2/193 (1%)
Query: 470 SQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKV 529
S ++ SS S ++ +D + S S + ++ +S + K
Sbjct: 585 SDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSD 644
Query: 530 SSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSS--GGS 587
S+S S + + S S S+ S D + SS SS S S +SS S
Sbjct: 645 SNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS 704
Query: 588 KHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSS 647
S+D S SSD SS+SS S + +D+S + S S S S SS+S
Sbjct: 705 SDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS 764
Query: 648 SSSVKQYISSHNS 660
S S SS +S
Sbjct: 765 SDSSDSSDSSDSS 777
Score = 51.2 bits (121), Expect = 3e-06
Identities = 51/199 (25%), Positives = 75/199 (37%), Gaps = 3/199 (1%)
Query: 462 EQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKE 521
+ + S + S S S K +N+ +D + S S +D S S +
Sbjct: 618 DSSDSKSDSSKSESDSSDSDSKSDSSDSNSSD-SSDNSDSSDSSNSSNSSDSSDSSDSSD 676
Query: 522 ELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSG 581
+SS+ SSD S S SS + SS ++S S+S
Sbjct: 677 SSSSSDSSNSSDSSDSSD--SSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS 734
Query: 582 SSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSS 641
S S S S+D + S SS SS S +D+S++ S S +S S
Sbjct: 735 SDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS 794
Query: 642 GSSSSSSSSVKQYISSHNS 660
SS+SS S SS +S
Sbjct: 795 SDSSNSSDSSNSSDSSDSS 813
Score = 50.4 bits (119), Expect = 6e-06
Identities = 50/164 (30%), Positives = 62/164 (37%), Gaps = 5/164 (3%)
Query: 497 DKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDH 556
D +KS S K + +D S S S S SSD S SS S D
Sbjct: 535 DDNDKSDSGKGKSDSSDSDSSDSSNSSDS----SDSSDSDSSDSNSSSDSDSSDSDSSDS 590
Query: 557 KEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSS 616
+ SS SS S S SS S +D S SD S+SS
Sbjct: 591 SDSDSSD-SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSD 649
Query: 617 SRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNS 660
S +D+S++ +S S S S SSSSS S SS +S
Sbjct: 650 SSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693
Score = 50.4 bits (119), Expect = 6e-06
Identities = 50/192 (26%), Positives = 74/192 (38%), Gaps = 1/192 (0%)
Query: 470 SQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKV 529
S +S SS +S K + ++ +D K S +D S S
Sbjct: 610 SSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSS 669
Query: 530 SSSERH-SSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSK 588
SS+ SSS S S SS + + + S SS S+S SS S
Sbjct: 670 DSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSS 729
Query: 589 HSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSS 648
+S+D + S SS SS S + +D+S + S S S +S S+ SS
Sbjct: 730 NSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSS 789
Query: 649 SSVKQYISSHNS 660
+S SS++S
Sbjct: 790 NSSDSSDSSNSS 801
Score = 50.1 bits (118), Expect = 7e-06
Identities = 79/373 (21%), Positives = 120/373 (32%), Gaps = 9/373 (2%)
Query: 290 DSVTGVPTNPSFQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQ 349
DS G ++ S + S+++ + +S N S + N S ++ +S S
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDS 905
Query: 350 EWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQE 409
+ + S E+S S N + S S S S+ S
Sbjct: 906 SDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNS 965
Query: 410 YTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDL-DVRDHYIAAQVEQQHKQG 468
+S S + S D + D D D ++
Sbjct: 966 SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS 1025
Query: 469 QSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIK 528
S +S SS +S ++ +D + S S +D S S +
Sbjct: 1026 DSSNSSDSSDSSD-------SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1078
Query: 529 VSSSERHSSSDEG-SGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGS 587
SSE SSD S S SS + S ++S S S S S S
Sbjct: 1079 SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1138
Query: 588 KHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSS 647
+S+D + S SS SS S +D+S++ S S S S SS S
Sbjct: 1139 SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1198
Query: 648 SSSVKQYISSHNS 660
S S SS +S
Sbjct: 1199 SDSSDSSDSSDSS 1211
Score = 49.7 bits (117), Expect = 1e-05
Identities = 56/207 (27%), Positives = 81/207 (39%), Gaps = 17/207 (8%)
Query: 459 AQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSA 518
++ + +S ++ S+S S ++ +D + S S ++ S
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688
Query: 519 SKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTS----SHK 574
S + SS+ SSD S S SS S D + S ++S S
Sbjct: 689 SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSD 748
Query: 575 HSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSK- 633
S+S S S S +S+D S SSD SS+SS ND+S++ S
Sbjct: 749 SSNSSDSSDSSDSSNSSDS-------SDSSDSSDSSDSSNSSDS-----NDSSNSSDSSD 796
Query: 634 MSKSSKSSGSSSSSSSSVKQYISSHNS 660
S SS SS SS SS SS S NS
Sbjct: 797 SSNSSDSSNSSDSSDSSDSSDSDSSNS 823
Score = 49.3 bits (116), Expect = 1e-05
Identities = 71/335 (21%), Positives = 108/335 (32%), Gaps = 10/335 (2%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+S + DS S N S + S++ SS DS+ + + S S
Sbjct: 938 SSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDS 997
Query: 376 QYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMS 435
+ N S S + D + S + + S S + S
Sbjct: 998 SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057
Query: 436 LDKYREKRKLETLDL-DVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKY 494
D ++ D D D +++ S +S SS +S ++
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD-------SSDSSD 1110
Query: 495 MADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISR 554
+D + S S +D S S + SSE SSD S S SS
Sbjct: 1111 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD--SSDSSDSSDSSDS 1168
Query: 555 DHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSS 614
+ +S + S S S S S S S+D + S SS S
Sbjct: 1169 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1228
Query: 615 SSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSS 649
S S + +D+S + S S S S SS S+S
Sbjct: 1229 SDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTS 1263
Score = 48.5 bits (114), Expect = 2e-05
Identities = 81/346 (23%), Positives = 123/346 (35%), Gaps = 26/346 (7%)
Query: 318 GNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQY 377
G DS +SD+ + + S S S+ DS ++ S ++ S S
Sbjct: 545 GKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS----SDSDSSDSDSSDSSDSDSSDSSN 600
Query: 378 NINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLD 437
+ + S S D SD S K E SK S + S D
Sbjct: 601 SSDSSDSSDSSDSSDSSDSSDSKSDSS--KSESDSSDSDSKSDSSDSNSSDSSDNSDSSD 658
Query: 438 KYREKRKLETLDL-DVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMA 496
++ D D D ++ S +S+SS +S +++ +
Sbjct: 659 SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSD--------SSDSSDS 710
Query: 497 DKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDH 556
D + S S + S+ + S S S+S + S S S+ S D
Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770
Query: 557 KEKHKEHPSSRHHTS--SHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSS 614
+ SS S S S S S+S S +S+D S SSD SS+S
Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS-------SDSSDSSDSDSSNS 823
Query: 615 SSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNS 660
S S +D+S++ S S SS SS S S SS+ +S +S
Sbjct: 824 SDSSNSSDSSDSSNS--SDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867
Score = 48.5 bits (114), Expect = 2e-05
Identities = 73/345 (21%), Positives = 114/345 (33%), Gaps = 14/345 (4%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+S + + DS+ S N S + S S S+ + DS+ ++ S S S
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDS--SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833
Query: 376 QYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMS 435
+ + S G SD S+ S+ S+ S
Sbjct: 834 DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD-----SNES 888
Query: 436 LDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYM 495
+ + D D D ++ S +S+SS S ++
Sbjct: 889 SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN-------SSDSSNS 941
Query: 496 ADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRD 555
+D + S S +D S S + SS +SS S S SS
Sbjct: 942 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001
Query: 556 HKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSS 615
+ + S ++S S+S S+S S S+D + S SS SS
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061
Query: 616 SSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNS 660
S +D+S + S S S S SS+SS S SS +S
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS 1106
Score = 47.8 bits (112), Expect = 4e-05
Identities = 83/357 (23%), Positives = 120/357 (33%), Gaps = 14/357 (3%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+S N S DS S N S + S+ SS+ + + S ++S S
Sbjct: 896 DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 955
Query: 376 QYNINFQQGPSISLHSGLHHRPDKI-------SDHSSVKQEYTHKAGSS--KHHGPISTT 426
N + S S S D S SS + + + SS S +
Sbjct: 956 SSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015
Query: 427 PGIIPQKMSLDKYREKRKLETLDL-DVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMK 485
S D ++ D D D ++ S +S SS +S
Sbjct: 1016 SNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1075
Query: 486 IPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSD--EGSG 543
+++ + +D + S S +D S S + SS SSD + S
Sbjct: 1076 SDSSDSSE-SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1134
Query: 544 KSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPV 603
S S+ S D E SS SS S S S S S +S+D +
Sbjct: 1135 SSDSSNSSDSSDSSESSDSSDSSDSSDSSDS-SDSSDSSDSSDSSNSSDSSDSSDSSDSS 1193
Query: 604 GLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNS 660
S SS SS S +D+S + S S S S SS SS S SS++S
Sbjct: 1194 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSS 1250
Score = 47.0 bits (110), Expect = 6e-05
Identities = 72/345 (20%), Positives = 114/345 (33%), Gaps = 4/345 (1%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+S + D SD+ + + S S S DS+ + + S ++S S +
Sbjct: 841 SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNES-SNSSDSSDSSN 899
Query: 376 QYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMS 435
+ + + S S + D +S + + +S S + S
Sbjct: 900 SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959
Query: 436 LDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYM 495
D ++ D D ++ S +S SS +S +++
Sbjct: 960 SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN-S 1018
Query: 496 ADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRD 555
+D S S +D S S + SS SSD S S SS
Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD--SSDSSDSSDSSDSS 1076
Query: 556 HKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSS 615
E S ++S S S S S S S+D + + S SS SS
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136
Query: 616 SSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNS 660
S +D+S + S S S S SS SS S SS++S
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1181
Score = 45.4 bits (106), Expect = 2e-04
Identities = 39/131 (29%), Positives = 51/131 (38%), Gaps = 2/131 (1%)
Query: 530 SSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKH 589
+ ++ + SD G GKS S S + S SS +S S S SS S
Sbjct: 532 NGNDDNDKSDSGKGKSDSSDSDSS--DSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSD 589
Query: 590 SADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSS 649
S+D S S S SS SS +D+S + SKS S S+SS
Sbjct: 590 SSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSD 649
Query: 650 SVKQYISSHNS 660
S SS +S
Sbjct: 650 SSDNSDSSDSS 660
Score = 42.7 bits (99), Expect = 0.001
Identities = 52/200 (26%), Positives = 72/200 (36%), Gaps = 31/200 (15%)
Query: 530 SSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKH 589
S+S+ ++S G+G + + S K K S +S+ S S S S S
Sbjct: 517 STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS 576
Query: 590 SADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSS 649
S+D S SSD S SS S N + + S S SS SS SS S S
Sbjct: 577 SSDS------DSSDSDSSDSSDSDSSDSS-----NSSDSSDSSDSSDSSDSSDSSDSKSD 625
Query: 650 SVKQYISSHNSVFNHPLPPPPPVTYQVGYGHLSTLVKLDKKPVETNGPDANHEYSTSSQH 709
S K S +S S D +++ + + S SS
Sbjct: 626 SSKSESDSSDSD--------------------SKSDSSDSNSSDSSDNSDSSDSSNSSNS 665
Query: 710 MDYKDTFDMLDSLLSAQGMN 729
D D+ D DS S+ N
Sbjct: 666 SDSSDSSDSSDSSSSSDSSN 685
Score = 42.4 bits (98), Expect = 0.002
Identities = 68/313 (21%), Positives = 107/313 (34%), Gaps = 57/313 (18%)
Query: 393 LHHRPDKISDHSSVKQEYTHKAGSSKH-----HGPISTTPGIIPQ--------------K 433
L+HR K ++ K+ TH G S+ GP S I +
Sbjct: 347 LNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHG 406
Query: 434 MSLDKYREKRKLETLDLD---------------------VRDHYIAAQVEQQHKQGQSQA 472
M L K K + E ++++ D Y + + + QG
Sbjct: 407 MILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPN 466
Query: 473 ASSSS-----VTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKI 527
+S S S Y +D+ + +G+ +D ++++
Sbjct: 467 SSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGN--------GSDSKGAEDD----D 514
Query: 528 KVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGS 587
S+S+ ++S G+G + + S K K S +S+ S S S S S
Sbjct: 515 SDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS 574
Query: 588 KHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSS 647
S+D S S SS+SS S +D+S + S SKS S S SS
Sbjct: 575 NSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS 634
Query: 648 SSSVKQYISSHNS 660
S K S NS
Sbjct: 635 DSDSKSDSSDSNS 647
Score = 42.4 bits (98), Expect = 0.002
Identities = 66/346 (19%), Positives = 105/346 (30%), Gaps = 1/346 (0%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+S + + DS S + S + S S S + DS+ + + + S S
Sbjct: 953 SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1012
Query: 376 QYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMS 435
+ N + S S D S + + S + S + S
Sbjct: 1013 SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1072
Query: 436 LDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYM 495
D E+ D + + + SS S S ++
Sbjct: 1073 SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1132
Query: 496 ADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEG-SGKSKHSSPHISR 554
+D + S S +D S S + SS+ SSD S S SS
Sbjct: 1133 SDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1192
Query: 555 DHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSS 614
+ S + S S S S S S S+D + S SS S
Sbjct: 1193 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDS 1252
Query: 615 SSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNS 660
S S S++ SKS + + S S S + S+H++
Sbjct: 1253 SDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHST 1298
Score = 38.1 bits (87), Expect = 0.029
Identities = 67/346 (19%), Positives = 111/346 (32%), Gaps = 22/346 (6%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+S + S +SD+ + + S S S + DS+ + + S S
Sbjct: 965 SSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNS 1024
Query: 376 QYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMS 435
+ N S S D S + + S S + S
Sbjct: 1025 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSES 1084
Query: 436 LDKYREKRKLETLDL-DVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKY 494
D ++ D D D ++ S +S SS +S +N+
Sbjct: 1085 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD- 1143
Query: 495 MADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEG----------SGK 544
+D E S S +D S S + +SS+ SSD S
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1203
Query: 545 SKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVG 604
S SS + S + S++ S S S S S +S+D
Sbjct: 1204 SSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSD--------- 1254
Query: 605 LSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSS 650
SSD S+S S+ + + + + +++ S S GS S+ S+S
Sbjct: 1255 -SSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 53.1 bits (126), Expect = 9e-07
Identities = 95/379 (25%), Positives = 131/379 (34%), Gaps = 71/379 (18%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+SG+ S H S + L G + G S +H + YS SGS
Sbjct: 1446 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYG----SGS 1501
Query: 376 QYNINFQQGPSISLHS-GLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKM 434
++ + S S HS GL HR + S SS ++ +G S HG +T G Q
Sbjct: 1502 GWSSSRGPYESGSSHSSGLGHRESR-SGQSSGYGQHGSSSGHSSTHGQHGSTSG---QSS 1557
Query: 435 SLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKY 494
S ++ A Q GQ + SS S
Sbjct: 1558 SCGQH------------------GASSGQSSSHGQHGSGSSQS----------------- 1582
Query: 495 MADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE---GSGKSKHSSPH 551
+ GS + P S S++ S S R SSS + G G+S H
Sbjct: 1583 --SGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 1640
Query: 552 -ISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSAD-------GIPPTVLRSPV 603
S + +H S H+S + S SG SS G +H + G + R
Sbjct: 1641 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSS 1700
Query: 604 GLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSVFN 663
G G S S SR R H + H+ S SGS SSS + S H+SVF
Sbjct: 1701 GHGRQGSGSGQSPSRGR-HGSGLGHS----SSHGQHGSGSGRSSSRGPYESRSGHSSVFG 1755
Query: 664 HPLPPPPPVTYQVGYGHLS 682
++ G GH S
Sbjct: 1756 Q---------HESGSGHSS 1765
Score = 51.6 bits (122), Expect = 3e-06
Identities = 94/379 (24%), Positives = 131/379 (34%), Gaps = 71/379 (18%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+SG+ S H S + L G + G S +H + Y + SGS
Sbjct: 976 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYR----SGS 1031
Query: 376 QYNINFQQGPSISLHS-GLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKM 434
++ + S S HS GL HR + S SS ++ +G S HG +T G Q
Sbjct: 1032 GWSSSRGPYESGSGHSSGLGHRESR-SGQSSGYGQHGSSSGHSSTHGQHGSTSG---QSS 1087
Query: 435 SLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKY 494
S ++ A Q GQ + SS S
Sbjct: 1088 SCGQH------------------GASSGQSSSHGQHGSGSSQS----------------- 1112
Query: 495 MADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE---GSGKSKHSSPH 551
+ GS + P S S++ S S R SSS + G G+S H
Sbjct: 1113 --SGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 1170
Query: 552 -ISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSAD-------GIPPTVLRSPV 603
S + +H S H+S + S SG SS G +H + G + R
Sbjct: 1171 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS 1230
Query: 604 GLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSVFN 663
G G S S SR R H + H+ S SGS SSS + S H+SVF
Sbjct: 1231 GHGRQGSGSGHSPSRGR-HGSGLGHS----SSHGQHGSGSGRSSSRGPYESRSGHSSVFG 1285
Query: 664 HPLPPPPPVTYQVGYGHLS 682
++ G GH S
Sbjct: 1286 Q---------HESGSGHSS 1295
Score = 50.1 bits (118), Expect = 7e-06
Identities = 94/379 (24%), Positives = 130/379 (34%), Gaps = 71/379 (18%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+SG+ S H S + L G + G S +H + YS SGS
Sbjct: 2386 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYG----SGS 2441
Query: 376 QYNINFQQGPSISLHS-GLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKM 434
++ + S S HS GL HR + S SS ++ +G S HG +T G Q
Sbjct: 2442 GWSSSRGPYESGSGHSSGLGHRESR-SGQSSGYGQHGSSSGHSSTHGQHGSTSG---QSS 2497
Query: 435 SLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKY 494
S ++ A Q GQ + SS S
Sbjct: 2498 SCGQH------------------GASSGQSSSHGQHGSGSSQS----------------- 2522
Query: 495 MADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE---GSGKSKHSSPH 551
+ GS + P S S++ S S R SSS + G G+S H
Sbjct: 2523 --SGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 2580
Query: 552 -ISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSAD-------GIPPTVLRSPV 603
S + +H S H+S + S SG SS G +H + G + R
Sbjct: 2581 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS 2640
Query: 604 GLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSVFN 663
G G S S SR R H + H+ S SGS SSS + H+SVF
Sbjct: 2641 GHGRQGSGSGQSPSRGR-HGSGLGHS----SSHGQHGSGSGRSSSRGPYESRLGHSSVFG 2695
Query: 664 HPLPPPPPVTYQVGYGHLS 682
++ G GH S
Sbjct: 2696 Q---------HESGSGHSS 2705
Score = 49.7 bits (117), Expect = 1e-05
Identities = 94/382 (24%), Positives = 137/382 (35%), Gaps = 80/382 (20%)
Query: 317 SGNISVQDSHTSDNLSMLATGM------PSTSYGLSSHQEWPQH-----QDSARTEQLYS 365
SG+ S Q H S + ++G S+SYG H+ +H Q S+ + Q
Sbjct: 368 SGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYG--QHESASRHSSGRGQHSSGSGQSPG 425
Query: 366 QKQETSLSGS-----QYNINF----QQGPSIS---LHSGLHHRPDKISDHSSVKQEYTHK 413
Q S SG Q+ F GP +S SG H + S+HSS ++
Sbjct: 426 HGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHH-ESSSEHSSGYTQHGSG 484
Query: 414 AGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAA 473
+G S HG + G Q + +QG S +
Sbjct: 485 SGHSSGHGQHGSRSG-------------------------------QSSRGERQGSSAGS 513
Query: 474 SSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSE 533
SSS + + + + + SGS + P +S S++ S
Sbjct: 514 SSSYGQHG-------SGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSG 566
Query: 534 RHSSS---DEGSGKSKHSSPHISRDHKEK-HKEHPSSRHHTSSHKHSHSHSGSSSGGSKH 589
R SS + GSG S SR + + +H SS H+S+H S SG SS +H
Sbjct: 567 RSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQH 626
Query: 590 -------SADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSG 642
S+ G + G S S SR R H +D H+ S SG
Sbjct: 627 GATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGR-HGSDFGHS----SSYGQHGSG 681
Query: 643 SSSSSSSSVKQYISSHNSVFNH 664
S SSS+ +S +S F H
Sbjct: 682 SGWSSSNGPHGSVSGQSSGFGH 703
Score = 49.3 bits (116), Expect = 1e-05
Identities = 92/392 (23%), Positives = 134/392 (34%), Gaps = 46/392 (11%)
Query: 342 SYGLSSHQEWPQHQDSAR---TEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPD 398
S G S H H R + S + E S S + ++ Q S S S H R
Sbjct: 710 SSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQG 769
Query: 399 KISDHSSVKQEYTHKAGSSKHHGP------ISTTPGIIP----QKMSLDKYREKRKLETL 448
S HS + + +G S HG S++ G Q ++
Sbjct: 770 SGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYS 829
Query: 449 DLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLR 508
+ ++Q GQS ++ +S + + A + + GS +
Sbjct: 830 QHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQ 889
Query: 509 IPIPPTDKSASKEELKMKIKVSSSERHSSSDE---GSGKSKHSSPHISRDHKEKHKEHPS 565
P S S + S S R SSS GSG+S S + +H S
Sbjct: 890 SPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGS 949
Query: 566 SRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSS----SSSSRKRL 621
H+SS++ S SG SS +H SS G SSS S SR+ L
Sbjct: 950 GSGHSSSYEQHGSRSGQSSRSEQHG---------------SSSGSSSSYGQHGSGSRQSL 994
Query: 622 HVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSVFNHPLPPPPPVTYQVGYGHL 681
S S GS S SSS Y S S ++ P Y+ G GH
Sbjct: 995 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRS--GSGWSSSRGP-----YESGSGHS 1047
Query: 682 STLVKLDKKPVETNG----PDANHEYSTSSQH 709
S L + + +++G ++ ST QH
Sbjct: 1048 SGLGHRESRSGQSSGYGQHGSSSGHSSTHGQH 1079
Score = 47.8 bits (112), Expect = 4e-05
Identities = 84/350 (24%), Positives = 119/350 (34%), Gaps = 57/350 (16%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+SG S H S + G + G SS E +H S+ + Y Q SGS
Sbjct: 2113 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE--RHGSSSGSSSRYGQHG----SGS 2166
Query: 376 QYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMS 435
+ + + S S HS R S HSS ++ +G S GP + G S
Sbjct: 2167 RQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSG----HSS 2222
Query: 436 LDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYM 495
+ E + Y H Q Q S+S +S + ++T +
Sbjct: 2223 VFGQHESGSGHS------SAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEG--SSTGQSS 2274
Query: 496 ADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRD 555
+ + SGS S S + GSG+S H S
Sbjct: 2275 SHGQHGSGS-------------------------SQSSSYGQQGSGSGQSPSRGRHGSGS 2309
Query: 556 -HKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSS 614
H + +H S +SS S SG SSG H + + G + G S
Sbjct: 2310 GHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS------GYTQHGSGSGH 2363
Query: 615 SSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSVFNH 664
SSS ++ H S S + GSSS SSSS Q+ S H
Sbjct: 2364 SSSYEQ-------HGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGH 2406
Score = 45.8 bits (107), Expect = 1e-04
Identities = 40/136 (29%), Positives = 52/136 (38%), Gaps = 14/136 (10%)
Query: 530 SSSERHSSSDEGSGKSKHSSPHISRD-HKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSK 588
S S + GSG+S H S H + +H S +SS S SG SSG
Sbjct: 1814 SQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGH 1873
Query: 589 HSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSS 648
H + + G + G S SSS ++ H S S + GSSS SS
Sbjct: 1874 HESSSWQSS------GYTQHGSGSGHSSSYEQ-------HGSRSGQSSRGEQHGSSSGSS 1920
Query: 649 SSVKQYISSHNSVFNH 664
SS Q+ S H
Sbjct: 1921 SSYGQHGSGSRQSLGH 1936
Score = 43.9 bits (102), Expect = 5e-04
Identities = 40/136 (29%), Positives = 52/136 (38%), Gaps = 14/136 (10%)
Query: 530 SSSERHSSSDEGSGKSKHSSPHISRD-HKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSK 588
S S + GSG+S H S H + +H S +SS S SG SSG
Sbjct: 1344 SQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGH 1403
Query: 589 HSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSS 648
H + + G + G S SSS ++ H S S + GSSS SS
Sbjct: 1404 HESSSWQSS------GCTQHGSGSGHSSSYEQ-------HGSRSGQSSRGERHGSSSGSS 1450
Query: 649 SSVKQYISSHNSVFNH 664
SS Q+ S H
Sbjct: 1451 SSYGQHGSGSRQSLGH 1466
Score = 43.1 bits (100), Expect = 0.001
Identities = 42/140 (30%), Positives = 50/140 (35%), Gaps = 12/140 (8%)
Query: 532 SERHSSSDEGSGKSKHSSPHISR-DHKEKHKEHPSSRHHTSSHKHSHSHSG--------- 581
S H GSG+S P+ SR H +H S H+S++ S SG
Sbjct: 2665 SSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 2724
Query: 582 SSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDA-SHNHHSKMSKSSKS 640
S+SG S T S G G S SS R + SH H S S S
Sbjct: 2725 STSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSS 2784
Query: 641 SGSSSSSSSSVKQYISSHNS 660
G S S Y S H S
Sbjct: 2785 YGQHGSGSGQSSGY-SQHGS 2803
Score = 41.6 bits (96), Expect = 0.003
Identities = 44/160 (27%), Positives = 60/160 (37%), Gaps = 22/160 (13%)
Query: 530 SSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKH 589
S E++S S + SG+ + S + +H S +SS+ S SG SSG S+H
Sbjct: 178 SYGEQNSDSHQSSGRGQCGS---GSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQH 234
Query: 590 SADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSS 649
+ + G S G S SS H S S + SSS SSS
Sbjct: 235 KSSSGQSS------GYSQHGSGSGHSSGY-------GQHGSRSGQSSRGERHRSSSGSSS 281
Query: 650 SVKQYISSHNSVFNH------PLPPPPPVTYQVGYGHLST 683
S Q+ S H P V + G GH S+
Sbjct: 282 SYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSS 321
Score = 40.8 bits (94), Expect = 0.005
Identities = 44/129 (34%), Positives = 54/129 (41%), Gaps = 14/129 (10%)
Query: 535 HSSS----DEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHS 590
HSSS GSG S + PH S + H S +S + S S SSG KH
Sbjct: 671 HSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHG 730
Query: 591 ADGIPPTVLRSPVGLSSDGISSS-----SSSSRKRLHVNDASHNHHSKMSKSSKSSGSSS 645
+ + RS SS G+SSS S S + H S + H S S GSSS
Sbjct: 731 SRSGQSS--RSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGH---SPSRVRHGSSS 785
Query: 646 SSSSSVKQY 654
SSS Q+
Sbjct: 786 GHSSSHGQH 794
Score = 40.4 bits (93), Expect = 0.006
Identities = 45/149 (30%), Positives = 54/149 (36%), Gaps = 16/149 (10%)
Query: 532 SERHSSSDEGSGKSKHSSPHISRD-HKEKHKEHPSSRHHTSSHKHSHSHSG--------- 581
S H GSG+S P+ SR H +H S H+S++ S SG
Sbjct: 1255 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 1314
Query: 582 SSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDA-SHNHHSKMSKSSKS 640
S+SG S T S G G S SS R + S H S S S
Sbjct: 1315 STSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSS 1374
Query: 641 -----SGSSSSSSSSVKQYISSHNSVFNH 664
SGS SSSS S +S F H
Sbjct: 1375 YGQHGSGSGWSSSSGRHGSGSGQSSGFGH 1403
Score = 40.4 bits (93), Expect = 0.006
Identities = 45/149 (30%), Positives = 56/149 (37%), Gaps = 16/149 (10%)
Query: 532 SERHSSSDEGSGKSKHSSPHISRD-HKEKHKEHPSSRHHTSSHKHSHSHSG--------- 581
S H GSG+S P+ SR H +H S H+S++ S SG
Sbjct: 1725 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 1784
Query: 582 SSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDA-SHNHHSKMSKSSKS 640
S+SG S T S G G S SSS ++ + S H S S S
Sbjct: 1785 STSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSS 1844
Query: 641 -----SGSSSSSSSSVKQYISSHNSVFNH 664
SGS SSSS S +S F H
Sbjct: 1845 YGQHGSGSGWSSSSGRHGSGSGQSSGFGH 1873
Score = 40.0 bits (92), Expect = 0.008
Identities = 53/174 (30%), Positives = 66/174 (37%), Gaps = 36/174 (20%)
Query: 527 IKVSSSERHSSS--DEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSS 584
++ S HSSS GSG SS SR H E S TS S SG SS
Sbjct: 310 VRHGSGSGHSSSHGQHGSG----SSYSYSRGHYE------SGSGQTSGFGQHESGSGQSS 359
Query: 585 GGSKHSADGIPPTVLRSPVGLSSDGISSS---SSSSRKRLHVNDASHNHHSKMSKSSKSS 641
G SKH + G + + G +S SSS SSSR+ +S+ H S+ S
Sbjct: 360 GYSKHGS-GSGHSSSQGQHGSTSGQASSSGQHGSSSRQ-----SSSYGQHESASRHSSGR 413
Query: 642 GSSSS------------SSSSVKQYISSHNSVFNHPLPPPPPVT---YQVGYGH 680
G SS S S H + F P V+ Y G+GH
Sbjct: 414 GQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGH 467
Score = 39.3 bits (90), Expect = 0.013
Identities = 52/174 (29%), Positives = 62/174 (35%), Gaps = 46/174 (26%)
Query: 534 RHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADG 593
RH S S S P + H H SS +SS+ S SG SSG +H
Sbjct: 2083 RHGSGSGRSSSSGQHGPGLGESSGFGH--HESSSGQSSSYSQHGSGSGHSSGYGQHG--- 2137
Query: 594 IPPTVLRSPVGLSSDGI---SSSSSSSRKRLHVNDA-----------------SHNHHSK 633
S G SS G SSS SSSR H + + S H
Sbjct: 2138 -------SRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS 2190
Query: 634 MSKSSKS-----SGSSSSSSSSVKQYISSHNSVFNHPLPPPPPVTYQVGYGHLS 682
S S S SGS SSS + S H+SVF ++ G GH S
Sbjct: 2191 GSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQ---------HESGSGHSS 2235
Score = 38.9 bits (89), Expect = 0.017
Identities = 89/365 (24%), Positives = 130/365 (35%), Gaps = 33/365 (9%)
Query: 317 SGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQ 376
SG+ S H S + + G ++ G SS + Q+ + T Q S Q S GS
Sbjct: 1761 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD----QEGSSTGQSSSHGQHGS--GSS 1814
Query: 377 YNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAG----SSKHHGPISTTPGIIPQ 432
+ ++ Q S S S R S HSS ++ +G S +H + G
Sbjct: 1815 QSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1874
Query: 433 KMSL---DKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIA 489
+ S Y + H + + +Q S + SSSS +
Sbjct: 1875 ESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHG------S 1928
Query: 490 NTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSS---DEGSGKSK 546
+ + + + SGS + P S S + S S SS + GSG S
Sbjct: 1929 GSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSS 1988
Query: 547 HSSPHISRDHKEK-HKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGL 605
SR + + +H SS H+S+H S SG SS +H A + S G
Sbjct: 1989 GLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGAS----SGQSSSHGQ 2044
Query: 606 SSDGISSSSSSSRKRLHVNDA-SHNHHSKMSKSSKS-----SGSSSSSSSSVKQYISSHN 659
G S SS R+ + H S+ S S SGS SSSS +
Sbjct: 2045 HGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGES 2104
Query: 660 SVFNH 664
S F H
Sbjct: 2105 SGFGH 2109
Score = 37.7 bits (86), Expect = 0.038
Identities = 40/128 (31%), Positives = 49/128 (38%), Gaps = 17/128 (13%)
Query: 530 SSSERHSSSDEGSGKSKHSSPHIS-RDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSK 588
SS H S GSG+S S H S H +++H S +S + S SG SS +
Sbjct: 698 SSGFGHKS---GSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQ 754
Query: 589 HSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSS 648
H + G G S S SR R H S S S GS +S S
Sbjct: 755 HGSGS------HQSSGHGRQGSGSGHSPSRVR-------HGSSSGHSSSHGQHGSGTSCS 801
Query: 649 SSVKQYIS 656
SS Y S
Sbjct: 802 SSCGHYES 809
Score = 37.7 bits (86), Expect = 0.038
Identities = 38/133 (28%), Positives = 47/133 (35%), Gaps = 13/133 (9%)
Query: 530 SSSERHSSSD--------EGSGKSKHSSPH----ISRDHKEKHKEHPSSRHHTSSHKHSH 577
S ERH SS GSG S+ SS H H H S H+SSH
Sbjct: 1204 SRGERHGSSSGSSSHYGQHGSG-SRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHG 1262
Query: 578 SHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKS 637
S SG SS + + +V S + S S + H S S +
Sbjct: 1263 SGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSST 1322
Query: 638 SKSSGSSSSSSSS 650
GSS+ SSS
Sbjct: 1323 FDQEGSSTGQSSS 1335
Score = 36.6 bits (83), Expect = 0.085
Identities = 45/145 (31%), Positives = 55/145 (37%), Gaps = 40/145 (27%)
Query: 530 SSSERHSSSDEGSGKSKHSSPHISR-DHKEKHKEHPSSRHHTSSH-KHSH---------- 577
S S R+ GSG+S H S H + +H S +SS+ H
Sbjct: 644 SQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGH 703
Query: 578 -SHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSK 636
S SG SSG S+H + SS SS RK H S S
Sbjct: 704 KSGSGQSSGYSQHGSG------------------SSHSSGYRK--------HGSRSGQSS 737
Query: 637 SSKSSGSSSSSSSSVKQYIS-SHNS 660
S+ GSSS SSS Q+ S SH S
Sbjct: 738 RSEQHGSSSGLSSSYGQHGSGSHQS 762
Score = 36.6 bits (83), Expect = 0.085
Identities = 41/139 (29%), Positives = 53/139 (38%), Gaps = 17/139 (12%)
Query: 530 SSSERHSSSDEGSGK-------SKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGS 582
S ERH SS S + S+ SS H + + PS H S HS SH
Sbjct: 1674 SRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSG--QSPSRGRHGSGLGHSSSHGQH 1731
Query: 583 SSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASH-----NHHSKMSKS 637
SG + S+ G P + S S SS H + + H H S +S
Sbjct: 1732 GSGSGRSSSRG-PYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS 1790
Query: 638 S--KSSGSSSSSSSSVKQY 654
S GSS+ SSS Q+
Sbjct: 1791 STFDQEGSSTGQSSSHGQH 1809
Score = 30.8 bits (68), Expect = 4.7
Identities = 41/152 (26%), Positives = 52/152 (34%), Gaps = 26/152 (17%)
Query: 532 SERHSSSDEGSGKSKHSSPHISRDHKE----KHKEHPSSRHHTSSHKHSHSH-------- 579
S + GSG+S + H S + +HK S H H
Sbjct: 202 SPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHG 261
Query: 580 --SGSSSGGSKH-------SADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNH 630
SG SS G +H S+ G + R +G G S S S HV S +
Sbjct: 262 SRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPS----HVRHGSGSG 317
Query: 631 HSKMSKSSKSSGSSSSSSSSVKQYISSHNSVF 662
HS S SGSS S S + S S F
Sbjct: 318 HSS-SHGQHGSGSSYSYSRGHYESGSGQTSGF 348
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 52.4 bits (124), Expect = 1e-06
Identities = 80/361 (22%), Positives = 127/361 (35%), Gaps = 49/361 (13%)
Query: 346 SSHQEWPQHQDSARTEQ-LYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHS 404
SS Q H +S+ Q + S +Q S G ++ QQ S HSG+ HR S
Sbjct: 1325 SSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHR-----QAS 1379
Query: 405 SVKQEYTHKAGS------SKHHGPISTTPGIIPQKMS---LDKYREKRKLETLDLDVRDH 455
S ++ H+ S S+ H S T + + ++E + ++ + R
Sbjct: 1380 SAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSR 1439
Query: 456 YIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTD 515
QV + + ++ S + A + ++ +++
Sbjct: 1440 SFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGG 1499
Query: 516 KSASKEELKMKIKVSSSERHS------SSDEGSGKSKHSSPHISRDHKEKH---KEHPSS 566
+ S E + S HS SD G+S S ++E+ H S
Sbjct: 1500 RQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGS 1559
Query: 567 RHH-----TSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRK-- 619
RHH S +HS G S+G G + R G S D S S+SR
Sbjct: 1560 RHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHY 1619
Query: 620 --------------RLHVND-ASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSVFNH 664
R H D ASH H ++SS+ SG+ + +SS Q SS +
Sbjct: 1620 GSAREQSRHGSRNPRSHQEDRASHGH---SAESSRQSGTRHAETSSGGQAASSQEQARSS 1676
Query: 665 P 665
P
Sbjct: 1677 P 1677
Score = 50.1 bits (118), Expect = 7e-06
Identities = 89/414 (21%), Positives = 142/414 (34%), Gaps = 64/414 (15%)
Query: 346 SSHQEWPQH-QDSARTEQLYSQKQETSLSGSQYNINFQ-QGPSISLHSGLHHRPDKISDH 403
SS Q +H + S+R + S +Q S +G ++ + Q Q S HSG+ H +
Sbjct: 1973 SSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVR 2032
Query: 404 SSVKQEYT-HKAGSSKHHGPISTTPGIIPQKMS---LDKYREKRKLETLDLDVRDHYIAA 459
S + Y+ +A S+ H S T + Q + ++E + ++ + R
Sbjct: 2033 DSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLY 2092
Query: 460 QVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSAS 519
QV + + S+ S A + +E +++ + S
Sbjct: 2093 QVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGS 2152
Query: 520 KEELKMKIKVSSSERHSS------SDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSH 573
+E + S HS SD G+S S SR +K + SRH S H
Sbjct: 2153 HQEQSVDRSGHSGSHHSHTTSQGRSDASRGQS--GSRSASRKTYDKEQSGDGSRHSGSHH 2210
Query: 574 KHSHSHSGSSSGGSKHSADGIPPTVLR---SPVGLSSDGISSSSSSSRKRLHVNDASHNH 630
+ S + SS P R S V SD S S R+ AS NH
Sbjct: 2211 HEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRS---GSASRNH 2267
Query: 631 HSK------------------------MSKSSKSSGSSSSSSSSVKQYISSHNSV----- 661
H ++SS+ SG+ + +SS Q SSH
Sbjct: 2268 HGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAG 2327
Query: 662 ----FNHPLPPPPPVTYQVGYGHLSTLVKLDKKPVETNGPDANHEYSTSSQHMD 711
+H +G+G S+ V+ D+ H S+ SQ D
Sbjct: 2328 ERHGSHHQQSADSSRHSGIGHGQASSAVR-----------DSGHRGSSGSQASD 2370
Score = 49.7 bits (117), Expect = 1e-05
Identities = 93/429 (21%), Positives = 150/429 (34%), Gaps = 61/429 (14%)
Query: 346 SSHQEWPQHQDSARTEQLYS-QKQETSLSGSQYNINFQQGPSISLHSGLHHRPDK-ISDH 403
SS Q +H +++ Q S Q+Q S G ++ QQ S SG R D +
Sbjct: 1649 SSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGD 1708
Query: 404 SSVKQEYTHKAGSSKHHGPISTTPGIIPQKMS---LDKYREKRKLETLDLDVRDHYIAAQ 460
S + +A S+ H S T + + ++E + ++ + R Q
Sbjct: 1709 SGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQ 1768
Query: 461 VEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASK 520
V + + + S + + A + +E +++ + S
Sbjct: 1769 VSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSH 1828
Query: 521 EELKMKIKVSSSERHS--SSDEGSGKSK--HSSPHISRDHKEKHKEHPSSRHHTSSH--- 573
E + S HS +S E S S+ S +SR + + + SRH S H
Sbjct: 1829 YEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEA 1888
Query: 574 -------KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRL----- 621
+HS G SSG G + G S D S S+SR L
Sbjct: 1889 SSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWE 1948
Query: 622 ------------HVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSV-------- 661
H + A H H + SS+ SG+ + SSS Q SSH
Sbjct: 1949 QSRDGSRHPGSHHEDRAGHGH---SADSSRQSGTRHTESSSRGQAASSHEQARSSAGERH 2005
Query: 662 -FNHPLPPPPPVTYQ-VGYGHLSTLVKLDKKPVETNGPDANHEYSTSSQHMDYKDTFDML 719
+H L + +G+G S+ V+ D+ H + SQ D + +
Sbjct: 2006 GSHHQLQSADSSRHSGIGHGQASSAVR-----------DSGHRGYSGSQASDSEGHSEDS 2054
Query: 720 DS-LLSAQG 727
D+ +SAQG
Sbjct: 2055 DTQSVSAQG 2063
Score = 48.5 bits (114), Expect = 2e-05
Identities = 67/335 (20%), Positives = 122/335 (36%), Gaps = 37/335 (11%)
Query: 324 DSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQ 383
+ H+ D+ + +G + SHQE + + R+ + S + S + +
Sbjct: 751 EGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWT 810
Query: 384 GPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHG-PISTTPGIIPQKMSLDKYREK 442
GPS + G HH + + S Q+ G G P S+ G + E+
Sbjct: 811 GPSTGVRQGSHHEQARDNSRHSASQD-----GQDTIRGHPGSSRRG------RQGSHHEQ 859
Query: 443 RKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKS 502
+ + +Q +GQS + S+S T + + ++ + ++
Sbjct: 860 SVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQS---RDGSRHSGSRHHEA 916
Query: 503 GSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKE 562
S + S+ + + SS + S S+ S S+ S SR+H+ +E
Sbjct: 917 SSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQE 976
Query: 563 -------HPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSS 615
HP S HH H HS S G+ H+ +S G ++SS
Sbjct: 977 QSRHGSRHPRS-HHEDRAGHGHSADSSRQSGTPHAE--------------TSSGGQAASS 1021
Query: 616 SSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSS 650
+ R + + H + + SS+ SG +SS
Sbjct: 1022 HEQARSSPGERHGSRHQQSADSSRHSGIPRRQASS 1056
Score = 48.5 bits (114), Expect = 2e-05
Identities = 79/345 (22%), Positives = 126/345 (36%), Gaps = 34/345 (9%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+SG+ S SDN S + +S+H + HQ S + + + SGS
Sbjct: 2681 DSGHRGYSGSQASDNEGH---SEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGS 2737
Query: 376 -QYNIN-FQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQK 433
Y ++ +Q S +G R + S H + H A S I PG +
Sbjct: 2738 FLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSA-SQDGQDTIRGHPG--SSR 2794
Query: 434 MSLDKYREKRKLETLDLDVRDH-YIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTE 492
Y + +++ H + +Q +GQS + S+S T E
Sbjct: 2795 GGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTT----------RNE 2844
Query: 493 KYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHI 552
+ D SGS R T S+ ++ + S R S +GS S+ S
Sbjct: 2845 EQSGDGSRHSGS---RHHEASTHADISRHSQAVQGQSEGSRR--SRRQGSSVSQDSDSEG 2899
Query: 553 SRDHKEKHKEHPSSRHHTSSH-------KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGL 605
+ E+ S HH S+ +H SH G HSAD + R
Sbjct: 2900 HSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQ-EDRAGHGHSADSSRQSGTRHT--Q 2956
Query: 606 SSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSS 650
+S G ++SS + R + +HH + + SS+ SG +SS
Sbjct: 2957 TSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASS 3001
Score = 48.1 bits (113), Expect = 3e-05
Identities = 77/335 (22%), Positives = 111/335 (33%), Gaps = 46/335 (13%)
Query: 340 STSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLH-HRPD 398
S+ + +S H E H D +R Q + E S + QG S+S S H D
Sbjct: 3174 SSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRR------QGSSVSQDSDSEGHSED 3227
Query: 399 KISDHSSVKQEYTHKAGSSKHHG---PISTTPGIIPQKMSLDKYREK--RKLETLDLDVR 453
S + + HG P S S D+ R+ R ET
Sbjct: 3228 SERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSS---- 3283
Query: 454 DHYIAAQVEQQHKQGQSQAAS------SSSVTSPIKMKIPIANTEKYMADKKE--KSGSL 505
Q H+Q +S S S IP + D + SGS
Sbjct: 3284 ----GGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGS- 3338
Query: 506 KLRIPIPPTDKSASKEELKMKIKVSS---------SERHSSSDEGSGKSKHSSPHISRDH 556
+D EE + VS S + S+ D G+S S + +
Sbjct: 3339 ------QASDSEGHSEESDTQ-SVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVS 3391
Query: 557 KEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSS-S 615
+ E R TS+ + SH + S+HSA +R G S G S
Sbjct: 3392 THEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYE 3451
Query: 616 SSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSS 650
S R + + H+H + +S S G S S S+S
Sbjct: 3452 QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS 3486
Score = 47.4 bits (111), Expect = 5e-05
Identities = 80/366 (21%), Positives = 129/366 (35%), Gaps = 68/366 (18%)
Query: 346 SSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGL-HHRPDK---IS 401
S H + + + S Q S S+ N +Q S HSG HH P S
Sbjct: 1512 SGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSS 1571
Query: 402 DHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYRE--KRKLETLDLDVRDHYIAA 459
HS V Q + + +S+ G + Q + + E +R+ E+ R+HY +A
Sbjct: 1572 RHSQVGQGESAGSKTSRRQG------SSVSQDRDSEGHSEDSERRSESAS---RNHYGSA 1622
Query: 460 QVEQQH-------------KQGQSQAASSSSVTSPIKMKI---PIANTEKYMADKKEKSG 503
+ + +H G S +S S T + ++ E+ + E+ G
Sbjct: 1623 REQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHG 1682
Query: 504 SLKLRIPIPPTDKSASKEELKMKI-----------KVSSSERHSSSDEGSGKSKH--SSP 550
S + TD + + + + S SE HS + S H + P
Sbjct: 1683 SRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGP 1742
Query: 551 HISRDHKEKHKEHPSSR--------HHTSSHKHS---HSHSGSSSGG------------S 587
H + H+E + R + S+H+ S H +G S+GG S
Sbjct: 1743 H-QQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSS 1801
Query: 588 KHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSS 647
+HSA +R G S G S + SH+ H+ + S S S S
Sbjct: 1802 RHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGS 1861
Query: 648 SSSVKQ 653
S +Q
Sbjct: 1862 RSVSRQ 1867
Score = 47.0 bits (110), Expect = 6e-05
Identities = 80/354 (22%), Positives = 129/354 (36%), Gaps = 49/354 (13%)
Query: 346 SSHQEWPQH-QDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHS 404
SS Q +H Q S+ + S +Q S +G ++ + QQ S HSG+ H +
Sbjct: 2622 SSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRD 2681
Query: 405 SVKQEYT-HKAGSSKHHGPISTTPGIIPQKMS---LDKYREKRKLETLDLDVRDHYIAAQ 460
S + Y+ +A ++ H S T + + ++E + + + Q
Sbjct: 2682 SGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQ 2741
Query: 461 VEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIP--PTDKSA 518
V Q+ SS T P + + + D S S + I P
Sbjct: 2742 VSTHE-----QSESSHGWTGP-STRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRG 2795
Query: 519 SKEELKMKIKVSSS------ERHSSSDEGSGKSKHSSPHISRDHKEKHKE-------HPS 565
++ + V SS H++S S S+ S S +++E H
Sbjct: 2796 GRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSG 2855
Query: 566 SRHHTSS-----HKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRK- 619
SRHH +S +HS + G S G + G + G S D S S+SR
Sbjct: 2856 SRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNH 2915
Query: 620 ---------------RLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSH 658
R H D + + HS + SS+ SG+ + +SS Q SSH
Sbjct: 2916 HGSAQEQLRDGSRHPRSHQEDRAGHGHS--ADSSRQSGTRHTQTSSGGQAASSH 2967
Score = 46.6 bits (109), Expect = 8e-05
Identities = 90/375 (24%), Positives = 125/375 (33%), Gaps = 61/375 (16%)
Query: 317 SGNISVQDSHTSDNLSMLATGMPSTSYGLS-----SHQEWPQHQDSARTEQLYSQKQETS 371
SG+ SHT+ G S+G S S Q + Q T S+ E S
Sbjct: 539 SGHSGSHHSHTTSQ------GRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEAS 592
Query: 372 LSG-----SQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTT 426
SQ GP S + G D S S E + S HHG
Sbjct: 593 SQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSA--- 649
Query: 427 PGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQ----HKQGQS--QAASSSSVTS 480
Q+ S D R R D H +A ++ H Q S QAASS
Sbjct: 650 -----QEQSRDGSRHPRSHHE---DRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQAR 701
Query: 481 PIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDE 540
+ + + AD SG+ + D S + + SE HS +
Sbjct: 702 SSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRD---SGHRGSSGSQATDSEGHSEDSD 758
Query: 541 GSGKSKHSSP-HISRDHKEKHKEHPSSR--------HHTSSHKHS---HSHSGSSSG--- 585
S H H + H+E ++ R + S+HK S H +G S+G
Sbjct: 759 TQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQ 818
Query: 586 ---------GSKHSADGIPPTVLRSPVGLSSDGISSS-SSSSRKRLHVNDASHNHHSKMS 635
S+HSA +R G S G S S R + + H+H +
Sbjct: 819 GSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQG 878
Query: 636 KSSKSSGSSSSSSSS 650
+S S G S S S+S
Sbjct: 879 RSDASRGQSGSRSAS 893
Score = 46.6 bits (109), Expect = 8e-05
Identities = 76/337 (22%), Positives = 125/337 (37%), Gaps = 45/337 (13%)
Query: 325 SHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQG 384
S SD S+ A G SHQE + + + R+ + S + S + + + G
Sbjct: 2375 SEDSDTQSVSAHGQAGPHQ--QSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTG 2432
Query: 385 PSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHG-PISTTPGIIPQKMSLDKYREKR 443
S G HH+ + S S QE G HG P S++ G R+
Sbjct: 2433 TSTGGRQGSHHKQARDSSRHSTSQE-----GQDTIHGHPGSSSGG-----------RQGS 2476
Query: 444 KLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSG 503
E L +D R + + QG+S A+ S + + ++ D SG
Sbjct: 2477 HYEQL-VD-RSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQ---TRNDEQSGDGSRHSG 2531
Query: 504 SLKLRIPIPPTDKSASKEELKMKIKVSSSERH---SSSDEGSGKSKHSSPHISRDHKEKH 560
S +++S+ + +V + +S + GS S+ S + E+
Sbjct: 2532 SRH--------HEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERW 2583
Query: 561 KEHPSSRHHTSSH-------KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSS 613
S HH S+ +H SH G HSAD + R +S G ++
Sbjct: 2584 SGSASRNHHGSAQEQLRDGSRHPRSHQ-EDRAGHGHSADSSRQSGTRHT--QTSSGGQAA 2640
Query: 614 SSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSS 650
SS + R + +HH + + SS+ SG +SS
Sbjct: 2641 SSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASS 2677
Score = 46.6 bits (109), Expect = 8e-05
Identities = 76/325 (23%), Positives = 115/325 (35%), Gaps = 40/325 (12%)
Query: 325 SHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQG 384
S SD S+ A G SHQE + + + R+ + S + S + + + G
Sbjct: 3671 SEDSDTQSVSAHGQAGPHQ--QSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAG 3728
Query: 385 PSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRK 444
PS G H + S S QE G G + G Y E+
Sbjct: 3729 PSTGGRQGSRHEQARDSSRHSASQE-----GQDTIRGHPGSRRG-----GRQGSYHEQSV 3778
Query: 445 LETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGS 504
+ + +Q GQS + S+S T E+ D SGS
Sbjct: 3779 DRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRET----------RNEEQSGDGSRHSGS 3828
Query: 505 LKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHP 564
R T +S+ + + + S R S +GS S+ S + E+ E
Sbjct: 3829 ---RHHEASTQADSSRHSQSGQGESAGSRR--SRRQGSSVSQDSDSEAYPEDSERRSESA 3883
Query: 565 SSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVN 624
S HH SS + S GS GS H + + S + S SS++++ H +
Sbjct: 3884 SRNHHGSSRE--QSRDGSRHPGSSHR---------DTASHVQSSPVQSDSSTAKEHGHFS 3932
Query: 625 DASHNHHSKMSKSSKSSGSSSSSSS 649
S + S +S GS SSSS
Sbjct: 3933 SLSQD--SAYHSGIQSRGSPHSSSS 3955
Score = 45.4 bits (106), Expect = 2e-04
Identities = 79/360 (21%), Positives = 127/360 (35%), Gaps = 47/360 (13%)
Query: 346 SSHQEWPQH-QDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHS 404
SS Q +H Q S+ + S +Q S +G ++ + QQ S HSG+ H +
Sbjct: 2946 SSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRD 3005
Query: 405 SVKQEYT-HKAGSSKHHGPISTTPGIIPQKMS---LDKYREKRKLETLDLDVRDHYIAAQ 460
S + Y+ +A ++ H S T + + ++E + + + Q
Sbjct: 3006 SGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQ 3065
Query: 461 VEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSL-KLRIPIPPTDKSAS 519
V Q+ SS T P + E+ + + + I P
Sbjct: 3066 VSTHE-----QSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGG 3120
Query: 520 KEELKMKIKVSSSER---HSSSDEGSGKSKHS-----SPHISRDHKEKHKEHPSSRHHTS 571
++ + V SS H S G+S S S SR + + + SSRH S
Sbjct: 3121 RQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVS 3180
Query: 572 SH----------KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRK-- 619
H +HS + G S G + G + G S D S S+SR
Sbjct: 3181 RHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHR 3240
Query: 620 --------------RLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSVFNHP 665
R H D + + HS + S+ SG+ + +SS Q SSH + P
Sbjct: 3241 GSVQEQSRHGSRHPRSHHEDRAGHGHS--ADRSRQSGTRHAETSSGGQAASSHEQARSSP 3298
Score = 45.1 bits (105), Expect = 2e-04
Identities = 79/344 (22%), Positives = 116/344 (33%), Gaps = 58/344 (16%)
Query: 344 GLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPD-KISD 402
G S+ H + AR +S QE Q I G S G HH S
Sbjct: 486 GTSTGGRQGSHHEQARDSSRHSASQE-----GQDTIRGHPGSSRGGRQGSHHEQSVNRSG 540
Query: 403 HSSVKQEYTHKAG-SSKHHGPISTTPGIIPQKMSLDKYREKRKLE-----TLDLDVRDHY 456
HS +T G S HG Q S R+ R E T R H
Sbjct: 541 HSGSHHSHTTSQGRSDASHG----------QSGSRSASRQTRNEEQSGDGTRHSGSRHHE 590
Query: 457 IAAQVEQ-QHKQ-GQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPT 514
++Q + +H Q GQ Q++ + + ++++ + D + SGS
Sbjct: 591 ASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRN------ 644
Query: 515 DKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHK 574
+++E+ + RH S S SR +H ++ SS SSH+
Sbjct: 645 HHGSAQEQSR------DGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHE 698
Query: 575 HSHSHSGSSSGG---------SKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVND 625
+ S +G G S+HS G S V S SS S ++ H D
Sbjct: 699 QARSSAGERHGSRHQLQSADSSRHSGTGHGQA--SSAVRDSGHRGSSGSQATDSEGHSED 756
Query: 626 -----------ASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSH 658
A H+ S + SG S S S +S+H
Sbjct: 757 SDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTH 800
Score = 44.3 bits (103), Expect = 4e-04
Identities = 72/345 (20%), Positives = 130/345 (37%), Gaps = 34/345 (9%)
Query: 316 NSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGS 375
+SG+ S SDN S + +S+H + HQ S + + + SGS
Sbjct: 3005 DSGHRGYSGSQASDNEGH---SEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGS 3061
Query: 376 -QYNIN-FQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQK 433
Y ++ +Q S +G R + S H + H A S I PG +
Sbjct: 3062 FLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSA-SQYGQDTIRGHPG--SSR 3118
Query: 434 MSLDKYREKRKLETLDLDVRDH-YIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTE 492
Y + +++ H + +Q +GQS + S+S T + ++
Sbjct: 3119 GGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQS---GDSS 3175
Query: 493 KYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHI 552
++ + ++ + + S+ + + + SS + S S+ S S+ S
Sbjct: 3176 RHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSA 3235
Query: 553 SRDHKEKHKE-------HPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGL 605
SR+H+ +E HP S HH H HS S G++H+
Sbjct: 3236 SRNHRGSVQEQSRHGSRHPRS-HHEDRAGHGHSADRSRQSGTRHAE-------------- 3280
Query: 606 SSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSS 650
+S G ++SS + R + + H + + SS+ SG +SS
Sbjct: 3281 TSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASS 3325
Score = 43.9 bits (102), Expect = 5e-04
Identities = 44/146 (30%), Positives = 61/146 (41%), Gaps = 18/146 (12%)
Query: 531 SSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRH-----HTSSHKHSHSHSGSS-- 583
S+ R + D+ SG S H H E SSRH SS + H GSS
Sbjct: 1215 SASRQTRKDKQSGDG---SRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVS 1271
Query: 584 --SGGSKHSADG--IPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSK 639
S +HS D + + R+ G S + S S H D + + HS + SS+
Sbjct: 1272 QDSDSERHSDDSERLSGSASRNHHGSSRE--QSRDGSRHPGFHQEDRASHGHS--ADSSR 1327
Query: 640 SSGSSSSSSSSVKQYISSHNSVFNHP 665
SG+ + SSS Q +SSH + P
Sbjct: 1328 QSGTHHTESSSHGQAVSSHEQARSSP 1353
Score = 43.5 bits (101), Expect = 7e-04
Identities = 80/359 (22%), Positives = 128/359 (35%), Gaps = 59/359 (16%)
Query: 346 SSHQEWPQH-QDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHS 404
SS Q H ++S+ + S +Q S +G ++ + QQ S HSG+ H S
Sbjct: 2298 SSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH-----GQAS 2352
Query: 405 SVKQEYTHKAGS------SKHHGPISTTPGIIPQKMS---LDKYREKRKLETLDLDVRDH 455
S ++ H+ S S+ H S T + + ++E + + R
Sbjct: 2353 SAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSG 2412
Query: 456 YIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTD 515
QV H+Q +S + + T + + K D S S + + I
Sbjct: 2413 SFLYQVST-HEQSESAHGRTGTSTGGRQ-----GSHHKQARDSSRHSTSQEGQDTIHGHP 2466
Query: 516 KSASK-------EELKMKIKVSSSERHSSSDEGSGKSKHS---SPHISRDHKEKHKEHPS 565
S+S E+L + S S ++ +G + H S SR + +
Sbjct: 2467 GSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDG 2526
Query: 566 SRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRS----------PVGLSSDGISSSSS 615
SRH S H + S + SS P R+ G S D S S
Sbjct: 2527 SRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGS 2586
Query: 616 SSRK----------------RLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSH 658
+SR R H D + + HS + SS+ SG+ + +SS Q SSH
Sbjct: 2587 ASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHS--ADSSRQSGTRHTQTSSGGQAASSH 2643
Score = 43.1 bits (100), Expect = 0.001
Identities = 32/120 (26%), Positives = 49/120 (40%), Gaps = 1/120 (0%)
Query: 532 SERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSA 591
S + S+ D G+S S I + + E R TS+ + SH + S+HSA
Sbjct: 1098 SHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSA 1157
Query: 592 DGIPPTVLRSPVGLSSDGISSS-SSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSS 650
+R+ G G S S R + + H+H + +S S G S S S+S
Sbjct: 1158 SQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSAS 1217
Score = 42.7 bits (99), Expect = 0.001
Identities = 88/412 (21%), Positives = 139/412 (33%), Gaps = 60/412 (14%)
Query: 346 SSHQEWPQHQD-SARTEQLYSQKQETSLSGSQYNINFQQGPSISLHS--GLHHRPDKISD 402
SS Q +H + S+R + S +Q S G ++ QQ S HS G +SD
Sbjct: 352 SSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSD 411
Query: 403 HSSVKQEYTHKAGSSKHHGPISTTPGIIPQK---MSLDKYREKRKLETLDLDVRDHYIAA 459
+ +A S+ H S T + + ++E + + + R
Sbjct: 412 RGH-RGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLY 470
Query: 460 QVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSAS 519
QV + + + +S A + +E +++ + S
Sbjct: 471 QVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGS 530
Query: 520 KEELKMKIKVSSSERHSS------SDEGSGKSKHSSPHISRDHKEKHKE---HPSSRHHT 570
E + S HS SD G+S S ++E+ + H SRHH
Sbjct: 531 HHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHE 590
Query: 571 SSH-----KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRK------ 619
+S +HS G SSG G + G S D S S+SR
Sbjct: 591 ASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQ 650
Query: 620 ----------RLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSV-------- 661
R H D + + HS + SS+ SG+ + +SS Q SSH
Sbjct: 651 EQSRDGSRHPRSHHEDRAGHGHS--ADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERH 708
Query: 662 -FNHPLPPPPPVTYQ-VGYGHLSTLVKLDKKPVETNGPDANHEYSTSSQHMD 711
H L + G+G S+ V+ D+ H S+ SQ D
Sbjct: 709 GSRHQLQSADSSRHSGTGHGQASSAVR-----------DSGHRGSSGSQATD 749
Score = 41.6 bits (96), Expect = 0.003
Identities = 56/175 (32%), Positives = 63/175 (36%), Gaps = 46/175 (26%)
Query: 530 SSSERHSSSDE---GSGKSKH--SSPHISRD-------HKEKHKEH--------PSSRHH 569
S SERHS E GS H SS SRD H+E H S HH
Sbjct: 1274 SDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHH 1333
Query: 570 TSSHKH-----SHSHSGSSSG---GSKH--SAD-----GIPPTVLRSPVGLSSDGISSSS 614
T S H SH + SS G GS+H SAD GI S V S SS S
Sbjct: 1334 TESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGS 1393
Query: 615 SSSRKRLHVND-----------ASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSH 658
+ H D A + S + SG SS S S +SSH
Sbjct: 1394 QVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSH 1448
Score = 41.2 bits (95), Expect = 0.003
Identities = 66/300 (22%), Positives = 113/300 (37%), Gaps = 47/300 (15%)
Query: 373 SGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQ 432
SG+ + G + S H P + H S Q+ A SS+H G IP+
Sbjct: 1005 SGTPHAETSSGGQAASSHEQARSSPGE--RHGSRHQQ---SADSSRHSG--------IPR 1051
Query: 433 KMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIK----MKIPI 488
+ + R+ H+ ++ + +G S+ + + SV+ + +
Sbjct: 1052 RQASSAVRDS-----------GHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQ 1100
Query: 489 ANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGS-GKSKH 547
+ + + +SGS ++ +SA + + S+ R S E + S+H
Sbjct: 1101 ESARDWSGGRSGRSGSFIYQVSTHEQSESAHG-----RTRTSTGRRQGSHHEQARDSSRH 1155
Query: 548 SSPHISRDHKEKHKEHPSSRH---HTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVG 604
S+ S++ ++ + HP SR S H+ S SG S H+ + RS
Sbjct: 1156 SA---SQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTT-----SQGRSDAS 1207
Query: 605 LSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSVFNH 664
G S+S +RK D S HS +S + SS S V Q SS + H
Sbjct: 1208 HGQSGSRSASRQTRKDKQSGDGSR--HSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRH 1265
Score = 40.8 bits (94), Expect = 0.005
Identities = 85/366 (23%), Positives = 124/366 (33%), Gaps = 55/366 (15%)
Query: 317 SGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQ 376
SG+ Q S + S PST SH + Q QDS+R +S QE Q
Sbjct: 2087 SGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYD--QAQDSSR----HSASQE-----GQ 2135
Query: 377 YNINFQQGPSISLHSGLHHRPD-KISDHSSVKQEYTHKAGSSK----HHGPISTTPGIIP 431
I GPS G H S HS +T G S G S +
Sbjct: 2136 DTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYD 2195
Query: 432 QKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQG-QSQAASSSSVTSPIKMKIPIAN 490
++ S D R D + V Q G ++ SSV+ ++
Sbjct: 2196 KEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQD-------SD 2248
Query: 491 TEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSP 550
+E + D + +SGS +++E+ + RH S S
Sbjct: 2249 SEGHSEDSERRSGSASRN------HHGSAQEQSR------DGSRHPRSHHEDRAGHGHSA 2296
Query: 551 HISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGG--------SKHSADG-------IP 595
SR H E+ S SSH+ + S +G G S+HS G +
Sbjct: 2297 ESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVR 2356
Query: 596 PTVLRSPVGLS---SDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVK 652
+ R G S+G S S + H H + S +S+G S S S +
Sbjct: 2357 DSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLY 2416
Query: 653 QYISSH 658
Q +S+H
Sbjct: 2417 Q-VSTH 2421
Score = 40.0 bits (92), Expect = 0.008
Identities = 83/369 (22%), Positives = 127/369 (34%), Gaps = 64/369 (17%)
Query: 346 SSHQEWPQH-QDSARTEQLYSQKQETSLSGSQYNINFQ-QGPSISLHSGLHHRPDKISDH 403
SS + +H Q+S+ + S +Q S +G ++ Q Q S HSG H
Sbjct: 676 SSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGH-----GQA 730
Query: 404 SSVKQEYTHKAGS------SKHHGPISTTPGIIPQKMS---LDKYREKRKLETLDLDVRD 454
SS ++ H+ S S+ H S T + + ++E + + + R
Sbjct: 731 SSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRS 790
Query: 455 HYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPI--- 511
QV HKQ +S + T + + + D S S + I
Sbjct: 791 GSFLYQVST-HKQSESSHGWTGPSTG-----VRQGSHHEQARDNSRHSASQDGQDTIRGH 844
Query: 512 ---PPTDKSASKEELKMKIKVSSSERHSS------SDEGSGKSKHSSPHISRDHKEKHKE 562
+ S E + S HS SD G+S S SR + + +
Sbjct: 845 PGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQS--GSRSASRTTRNEEQS 902
Query: 563 HPSSRHHTSSH----------KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISS 612
SRH S H +HS + G S G G + G S D
Sbjct: 903 RDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERW 962
Query: 613 SSSSSRK----------------RLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYIS 656
S S+SR R H D + + HS + SS+ SG+ + +SS Q S
Sbjct: 963 SGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHS--ADSSRQSGTPHAETSSGGQAAS 1020
Query: 657 SHNSVFNHP 665
SH + P
Sbjct: 1021 SHEQARSSP 1029
Score = 40.0 bits (92), Expect = 0.008
Identities = 96/449 (21%), Positives = 142/449 (31%), Gaps = 121/449 (26%)
Query: 346 SSHQEWPQHQDSA-RTEQLYSQKQETSLSGSQYNINFQQGPSI--SLHSGLHHRPDKISD 402
S H++ H SA R+ Q ++ ETS SG Q + +Q S H H + S
Sbjct: 3256 SHHEDRAGHGHSADRSRQSGTRHAETS-SGGQAASSHEQARSSPGERHGSRHQQSADSSR 3314
Query: 403 HSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVE 462
HS + + A H S + Q + + E+ ++ V H A +
Sbjct: 3315 HSGIPRGQASSAVRDSRHWGSSGS-----QASDSEGHSEESDTQS----VSGHGQAGPHQ 3365
Query: 463 QQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEE 522
Q H++ + S S + Y E+S S R + S E
Sbjct: 3366 QSHQESARDRSGGRSGRS---------GSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHE 3416
Query: 523 LKMKIKVSSSERHSSSDEGSG-----------------------KSKHSSPH-------- 551
+ S RHS+S EG +S HS H
Sbjct: 3417 -----QARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQG 3471
Query: 552 -------------ISRDHKEKHKEHPSSRHHTSSH----------KHSHSHSGSSSGGSK 588
SR + + SRH S H +HS S G S+G
Sbjct: 3472 RSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRT 3531
Query: 589 HSADGIPPTVLRSPVGLSSDGISSSSSSSRKRL-----------------HVNDASHNHH 631
G + G S D S S+SR H + A H H
Sbjct: 3532 SRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGH- 3590
Query: 632 SKMSKSSKSSGSSSSSSSSVKQYISSHNSV---------FNHPLPPPPPVTYQVGYGHLS 682
++SS+ SG+ + +SS Q SSH +H +G+G S
Sbjct: 3591 --SAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQAS 3648
Query: 683 TLVKLDKKPVETNGPDANHEYSTSSQHMD 711
+ V+ D+ H S+ SQ D
Sbjct: 3649 SAVR-----------DSGHRGSSGSQASD 3666
Score = 40.0 bits (92), Expect = 0.008
Identities = 39/149 (26%), Positives = 59/149 (39%), Gaps = 27/149 (18%)
Query: 528 KVSSSERHSSSDEGSGKSKH--SSPHISRDHKEKHKEHPSSR--------HHTSSHKHS- 576
+ S SE HS + S H + PH + H+E + + R + S+H+ S
Sbjct: 3663 QASDSEGHSEDSDTQSVSAHGQAGPH-QQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSE 3721
Query: 577 --HSHSGSSSGG------------SKHSADGIPPTVLRSPVGLSSDGISSS-SSSSRKRL 621
H +G S+GG S+HSA +R G G S S R
Sbjct: 3722 SAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRS 3781
Query: 622 HVNDASHNHHSKMSKSSKSSGSSSSSSSS 650
+ + H+H + +S S G S S S+S
Sbjct: 3782 GHSGSHHSHTTSQGRSDASHGQSGSRSAS 3810
Score = 39.7 bits (91), Expect = 0.010
Identities = 76/351 (21%), Positives = 125/351 (35%), Gaps = 59/351 (16%)
Query: 335 ATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSG-------SQYNINFQQGPSI 387
A G TS G Q +DS+R SQ+ + ++ G + +++Q
Sbjct: 3399 AHGRTRTSTGRRQGSHHEQARDSSRHSA--SQEGQDTIRGHPGSSRRGRQGSHYEQSVDR 3456
Query: 388 SLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLET 447
S HSG HH H++ + G S G S + + S D R
Sbjct: 3457 SGHSGSHH------SHTTSQGRSDASRGQS---GSRSASRQTRNDEQSGDGSRHSWS--- 3504
Query: 448 LDLDVRDHYIAAQVEQ-QHKQ-GQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSL 505
H + Q + +H Q GQ Q+A + + ++++ + D + SGS
Sbjct: 3505 -----HHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSA 3559
Query: 506 KLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPS 565
+ +++E+ + RH +S S SR H E+ S
Sbjct: 3560 SRN------HRGSAQEQSR------DGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSS 3607
Query: 566 SRHHTSSHKHSHSHSGSSSGG--------SKHSADG-------IPPTVLRSPVGLS---S 607
SSH+ + S +G G S+HS G + + R G S
Sbjct: 3608 GGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDS 3667
Query: 608 DGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSH 658
+G S S + H H + S +S+G S S S + Q +S+H
Sbjct: 3668 EGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQ-VSTH 3717
Score = 37.7 bits (86), Expect = 0.038
Identities = 72/317 (22%), Positives = 111/317 (35%), Gaps = 43/317 (13%)
Query: 351 WPQHQDSARTEQLYSQKQ--------ETSLSGSQYNINFQQGPSISLHSGLHHRPDKISD 402
W Q +D +R + + + + + SG+++ +G + S H P +
Sbjct: 326 WEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGE--R 383
Query: 403 HSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVE 462
H S Q+ A SS+H +T G +S +R + D + Q
Sbjct: 384 HGSGHQQ---SADSSRHS---ATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSV 437
Query: 463 QQH-KQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKE 521
H K G Q + S + + + Y E+ S R + S
Sbjct: 438 SGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHH 497
Query: 522 ELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSG 581
E + S RHS+S EG + P SR ++ S H S ++ HS S
Sbjct: 498 E-----QARDSSRHSASQEGQDTIR-GHPGSSRGGRQ------GSHHEQSVNRSGHSGSH 545
Query: 582 SSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRK-RLHVNDASHNHHSKMSKSSKS 640
S S+ +D +S G S S S+SR+ R HS S
Sbjct: 546 HSHTTSQGRSD-------------ASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEAS 592
Query: 641 SGSSSSSSSSVKQYISS 657
S + SS S V Q SS
Sbjct: 593 SQADSSRHSQVGQGQSS 609
Score = 37.0 bits (84), Expect = 0.065
Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 10/133 (7%)
Query: 533 ERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSAD 592
ER SSD GKS S ++R E + P T + S S G ++
Sbjct: 258 ERSRSSD---GKS---SSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSE 311
Query: 593 GIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVK 652
+ R+ G + + S S R H D + + HS + SS+ SG+ + +SS
Sbjct: 312 RHSGSASRNHHGSAWE--QSRDGSRHPRSHDEDRASHGHS--ADSSRQSGTRHAETSSRG 367
Query: 653 QYISSHNSVFNHP 665
Q SSH + P
Sbjct: 368 QTASSHEQARSSP 380
Score = 35.8 bits (81), Expect = 0.14
Identities = 34/126 (26%), Positives = 46/126 (36%), Gaps = 20/126 (15%)
Query: 532 SERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSA 591
SERHS S + ++ H S + + HP S H H HS S G++H+
Sbjct: 310 SERHSGS---ASRNHHGS---AWEQSRDGSRHPRS-HDEDRASHGHSADSSRQSGTRHAE 362
Query: 592 DGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSS--------GS 643
T R S + SS H A + HS + SS GS
Sbjct: 363 -----TSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGS 417
Query: 644 SSSSSS 649
S S +S
Sbjct: 418 SGSQAS 423
Score = 34.7 bits (78), Expect = 0.32
Identities = 69/347 (19%), Positives = 111/347 (31%), Gaps = 39/347 (11%)
Query: 321 SVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNIN 380
S + H+ ++ + +G SHQE + R+ + S + S + +
Sbjct: 1072 SDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAH 1131
Query: 381 FQQGPSISLHSGLHHRPDKISDHSSVKQEY--THKAGSSKHHGPISTTPGIIPQKMSLDK 438
+ S G HH + S S QE T +A G + + S+D+
Sbjct: 1132 GRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSH----HEQSVDR 1187
Query: 439 YREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADK 498
+ + +Q GQS + S+S T +K D
Sbjct: 1188 SGHSGSHHS--------HTTSQGRSDASHGQSGSRSASRQT----------RKDKQSGDG 1229
Query: 499 KEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERH--SSSDEGSGKSKHSSPHISRDH 556
SGS + D S + + + S + RH SS + S +HS
Sbjct: 1230 SRHSGS-RHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSG 1288
Query: 557 KEKHKEHPSSR-------HHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDG 609
H SSR H H+ + G S+ S+ S + S +
Sbjct: 1289 SASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQ 1348
Query: 610 ISSSSSSSRKRLHVNDASHNHHS-----KMSKSSKSSGSSSSSSSSV 651
SS H A + HS + S + + SG SS S V
Sbjct: 1349 ARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQV 1395
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 51.2 bits (121), Expect = 3e-06
Identities = 47/167 (28%), Positives = 66/167 (39%), Gaps = 29/167 (17%)
Query: 512 PPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTS 571
PP A + ++ + R SSS S S SS S
Sbjct: 2509 PPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSS---------------------S 2547
Query: 572 SHKHSHSHSGSSSGGSKHSADGIPPTVLR--------SPVGLSSDGISSSSSSSRKRLHV 623
S S S SGSSS S+ S+ + P V +P +G + ++++
Sbjct: 2548 SSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRS 2607
Query: 624 NDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSVFNHPLPPPP 670
+ +S + S S SS SS SSSSSSSS SS +S + P P P
Sbjct: 2608 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP 2654
Score = 42.4 bits (98), Expect = 0.002
Identities = 48/228 (21%), Positives = 84/228 (36%), Gaps = 15/228 (6%)
Query: 428 GIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIP 487
G ++ + + ++R +++ I+++ + +S+A S S+ + P
Sbjct: 725 GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSP 784
Query: 488 IANTEKYMADKKEKSGS----LKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSG 543
+ ++ +SGS K R P P +S+S K K K S + HSSS
Sbjct: 785 CPKQKSQTPPRRSRSGSSQPKAKSRTP-PRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPK 843
Query: 544 KSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPV 603
+ P + E + S + S S S+HS G P ++S
Sbjct: 844 VKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSST 903
Query: 604 GLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSV 651
SSS + + ++ +H SGSSS S S V
Sbjct: 904 PPRQSPSRSSSPQPKVKAIISPRQRSH----------SGSSSPSPSRV 941
Score = 40.4 bits (93), Expect = 0.006
Identities = 93/453 (20%), Positives = 162/453 (35%), Gaps = 52/453 (11%)
Query: 231 ELLDELTHEFLQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVD 290
E+ ++L FL LE P+ K ++ R++ + V + + + + + +L
Sbjct: 1350 EVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVL-- 1407
Query: 291 SVTGVPTNPSFQKPSTSAFPAP---VPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSS 347
VP PS ++ S+++ P +P S S S S
Sbjct: 1408 --DAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPG 1465
Query: 348 HQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVK 407
++ P+ R+E S + + + P ++ + L + ++ SSV
Sbjct: 1466 MKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELN-NKCLTPQRERSGSESSVD 1524
Query: 408 QEYT--------HKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAA 459
Q+ ++GSS+ + P PQ+ S K +T
Sbjct: 1525 QKTVARTPLGQRSRSGSSQE---LDVKPSASPQERSESDSSPDSKAKT----------RT 1571
Query: 460 QVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSAS 519
+ Q+ + G S S S SP + + + + + DK + + P K+ +
Sbjct: 1572 PLRQRSRSGSSPEVDSKSRLSPRRSR---SGSSPEVKDKPRAAPRAQSGSDSSPEPKAPA 1628
Query: 520 KEELKMKIKV-SSSERHSSSDEGSGKSKHSSPH------------ISRDHKEKHKEHPSS 566
L + + SSS+ S EGS ++ S H S + K K + P
Sbjct: 1629 PRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRR 1688
Query: 567 RHHTSS----HKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLH 622
R SS K S S+ S + PP RSP +SS + S SSR+R
Sbjct: 1689 RSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSP-SVSSPEPAEKSRSSRRRRS 1747
Query: 623 VNDASHNHHSK--MSKSSKSSGSSSSSSSSVKQ 653
+ S+ S S K G S S S ++
Sbjct: 1748 ASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRRE 1780
Score = 37.7 bits (86), Expect = 0.038
Identities = 40/155 (25%), Positives = 60/155 (38%), Gaps = 14/155 (9%)
Query: 497 DKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDH 556
D + ++ K P PP S +E + ++ + +S+ SSP R
Sbjct: 152 DPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKK 211
Query: 557 KEKHKEHPSSRHHTSSHKHSH------SHSGSSSGGSKHSADGIP-PTVLRSPVGLSSDG 609
K K+H R + S K H S S K S P P R+ S+D
Sbjct: 212 SSKKKKH---RSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADS 268
Query: 610 ISSSSSS-SRKRLHVNDASHNHHSKMSKSSKSSGS 643
SSS +S SR R + A+ H + ++ S S S
Sbjct: 269 ASSSDTSRSRSR---SAAAKTHTTALAGRSPSPAS 300
Score = 34.7 bits (78), Expect = 0.32
Identities = 59/282 (20%), Positives = 106/282 (37%), Gaps = 37/282 (13%)
Query: 401 SDHSSVKQEYTHKAGSSKHHGPIST------TPGIIPQKMSLDKYREKRKLETLDLDVRD 454
S+ SS ++E + KH + +P ++ S DK R++ + T
Sbjct: 200 SESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTP------ 253
Query: 455 HYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPT 514
A + + H+ + +ASSS + + A K + +L R P P +
Sbjct: 254 ---APKSRRAHRSTSADSASSSDTS----------RSRSRSAAAKTHTTALAGRSPSPAS 300
Query: 515 DKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHK 574
+ + + +S++R SS + + + +D KEK PS SS
Sbjct: 301 GRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSS-T 359
Query: 575 HSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKM 634
+ + +H G P + +P LS + ++ S +S R +
Sbjct: 360 GPEPPAPTPLLAERHG--GSPQPLATTP--LSQEPVNPPSEASPTR------DRSPPKSP 409
Query: 635 SKSSKSSGSSSSSSSSVKQYISSH-NSVFNHPLPPPPPVTYQ 675
K +SS S SS S +S H +S P P P P +++
Sbjct: 410 EKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHR 451
Score = 32.7 bits (73), Expect = 1.2
Identities = 70/301 (23%), Positives = 105/301 (34%), Gaps = 25/301 (8%)
Query: 295 VPTNPSFQKPSTSAFPAPVP----LNSGNISVQDSHTSDNLSML---ATGMPSTSYGLSS 347
VP+ S Q A PV L+SG ++ S D+ ML A G+P + G
Sbjct: 2451 VPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPP 2510
Query: 348 HQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSS-- 405
Q Q SA ++++ +S S S + + S S S S+ SS
Sbjct: 2511 ASTGAQ-QPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP 2569
Query: 406 VKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQH 465
V+ E K S P P + + K + + + ++
Sbjct: 2570 VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS 2629
Query: 466 KQGQSQAASSS----SVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKE 521
S ++SSS S +SP K K + KK G + R P P D
Sbjct: 2630 SSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSR 2689
Query: 522 EL--------KMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSR--HHTS 571
L + + S ++ SSS E + S HK + +E PS R H S
Sbjct: 2690 SLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHK-RRRETPSPRPMRHRS 2748
Query: 572 S 572
S
Sbjct: 2749 S 2749
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 48.9 bits (115), Expect = 2e-05
Identities = 49/135 (36%), Positives = 62/135 (45%), Gaps = 18/135 (13%)
Query: 539 DEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKH---SADGIP 595
D G+ KS + +D E+ + SS +SS S S SGS + G + + DG
Sbjct: 2537 DSGNPKSPDKA-QAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGC 2595
Query: 596 PTVLR----------SPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSS 645
T R SP SS SSSSSSS + +S + S S SS SS SSS
Sbjct: 2596 GTGGRNCSAASSRAASPASSSSSSSSSSSSSSSS----SSSSSSSSSSSSSSSSSSSSSS 2651
Query: 646 SSSSSVKQYISSHNS 660
SSSSS SS +S
Sbjct: 2652 SSSSSSSSSSSSSSS 2666
Score = 48.1 bits (113), Expect = 3e-05
Identities = 45/160 (28%), Positives = 69/160 (43%), Gaps = 14/160 (8%)
Query: 515 DKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEH---PSSRHHTS 571
DK+ ++++ + + SSS SS S S S + +K+ + R+ ++
Sbjct: 2545 DKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSA 2604
Query: 572 SHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHH 631
+ + S + SSS S S+ SS SSSSSSS + +S +
Sbjct: 2605 ASSRAASPASSSSSSSSSSSSSS-----------SSSSSSSSSSSSSSSSSSSSSSSSSS 2653
Query: 632 SKMSKSSKSSGSSSSSSSSVKQYISSHNSVFNHPLPPPPP 671
S S SS SS SSSSSSS+ + S + P P P
Sbjct: 2654 SSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGP 2693
Score = 39.7 bits (91), Expect = 0.010
Identities = 48/193 (24%), Positives = 71/193 (36%), Gaps = 13/193 (6%)
Query: 489 ANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHS 548
A E+ A++ E S S + S+S E + E + D G G +
Sbjct: 2547 AQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETE-----GEEEGDKNGDGGCGTGGRN 2601
Query: 549 SPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSD 608
S SS +SS S S S SSS S S+ + S SS
Sbjct: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661
Query: 609 GISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQ----YISSHNSVFNH 664
SSSSSSS + S + + + ++ S ++ + + KQ S+H+
Sbjct: 2662 SSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKT 2721
Query: 665 PLP----PPPPVT 673
P P PPP T
Sbjct: 2722 PAPQPQAPPPQPT 2734
Score = 37.7 bits (86), Expect = 0.038
Identities = 36/134 (26%), Positives = 50/134 (37%), Gaps = 4/134 (2%)
Query: 459 AQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSA 518
AQ EQ + ++SSSS +S + +E ++ +K+G ++
Sbjct: 2547 AQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGD----GGCGTGGRNC 2602
Query: 519 SKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHS 578
S + SSS SSS S S SS S SS +SS S S
Sbjct: 2603 SAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2662
Query: 579 HSGSSSGGSKHSAD 592
S SSS S D
Sbjct: 2663 SSSSSSSSSTTDED 2676
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 48.5 bits (114), Expect = 2e-05
Identities = 52/210 (24%), Positives = 80/210 (38%), Gaps = 24/210 (11%)
Query: 468 GQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLR----IPIPPTDKSASKEEL 523
G +++ + S K + P K +D S S K++ + IP +KS S E+
Sbjct: 203 GIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEM 262
Query: 524 KMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSS 583
++K S + S+ S+ SP SR +K + H R H+ HS + S +
Sbjct: 263 SSRVK--SYNQASTRSRPQSHSQSRSPRRSRSGSQK-RTHSRVRSHSWKRNHSRARSRTR 319
Query: 584 SG---------GSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKM 634
G S+ + G R+P S S + S R SH+H
Sbjct: 320 KGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKER--------SHSHSRSS 371
Query: 635 SKSSKSSGSSSSSSSSVKQYISSHNSVFNH 664
SK GSSS S + S N +H
Sbjct: 372 SKERDHRGSSSPRKESGRSQSGSPNKQRDH 401
Score = 35.4 bits (80), Expect = 0.19
Identities = 32/104 (30%), Positives = 44/104 (42%), Gaps = 4/104 (3%)
Query: 516 KSASKEELKMKIKVSSSE-RHSSSDEGSGKSKHSSPHISRDHKEKH---KEHPSSRHHTS 571
+++SKE+ + + S E HS S S +S S + R K + S++ T
Sbjct: 609 RASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTP 668
Query: 572 SHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSS 615
S SHS S SGG S D S L + SSSSS
Sbjct: 669 SKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712
Score = 33.5 bits (75), Expect = 0.72
Identities = 38/149 (25%), Positives = 60/149 (40%), Gaps = 21/149 (14%)
Query: 516 KSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDH---KEKHKEHPSSRHHTSS 572
+S SKE + + + S ER S + RDH + +K+ SR SS
Sbjct: 561 RSPSKERDRRRWRSPSKERERRQSRSSSEE--------RDHSRSRSPNKQSGYSRPRASS 612
Query: 573 HKHSHSHSGSSSGGSKHS--------ADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVN 624
+ +HS S + S HS +D TV RSP S + +SS S+ R
Sbjct: 613 KEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSP--TRTSSLSQNRTPSK 670
Query: 625 DASHNHHSKMSKSSKSSGSSSSSSSSVKQ 653
+SH+ + S S S + ++ +
Sbjct: 671 TSSHSPSTFPSGGQTLSQDDSQADATTSK 699
Score = 32.7 bits (73), Expect = 1.2
Identities = 38/150 (25%), Positives = 53/150 (35%), Gaps = 12/150 (8%)
Query: 508 RIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDH---KEKHKEHP 564
R P D+S S+ K + + R S ++ S+ SP+ +RD + +K
Sbjct: 405 RSPNKARDRSRSRSPYKARDR----SRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARD 460
Query: 565 SSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTV-----LRSPVGLSSDGISSSSSSSRK 619
SR + + S S S S HS G P RSP S SSS R
Sbjct: 461 HSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERD 520
Query: 620 RLHVNDASHNHHSKMSKSSKSSGSSSSSSS 649
S + S+S S S S
Sbjct: 521 HRRSRSPSKERQRRQSRSPNKERDRSQSRS 550
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 48.5 bits (114), Expect = 2e-05
Identities = 43/137 (31%), Positives = 54/137 (39%), Gaps = 5/137 (3%)
Query: 531 SSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHS 590
S +R S D S S S H R H ++ SS+H + HK+S S S S+
Sbjct: 884 SRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSR 943
Query: 591 ADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSS 650
+ T RS S G S SSS SR R S HS +S S S S+ S
Sbjct: 944 SRSRSHTRERS----RSRGRSRSSSCSRSRSKRRSRSTTAHS-WQRSRSYSRDRSRSTRS 998
Query: 651 VKQYISSHNSVFNHPLP 667
Q S + H P
Sbjct: 999 PSQRSGSRKRSWGHESP 1015
Score = 47.4 bits (111), Expect = 5e-05
Identities = 48/214 (22%), Positives = 77/214 (35%), Gaps = 7/214 (3%)
Query: 438 KYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMAD 497
++++K+K + R H A E++ + +S S K A +
Sbjct: 674 RHKKKKKHKKSSKHKRKH--KADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGP 731
Query: 498 KKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHK 557
K E GS P PP + ++++ + + + DEG G S S H R HK
Sbjct: 732 KPEPPGSGS---PAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSS-SQDHGGRKHK 787
Query: 558 EKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTV-LRSPVGLSSDGISSSSSS 616
+ R + SH S G + S D + +SP S + S S
Sbjct: 788 GELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGS 847
Query: 617 SRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSS 650
R + + S+ S SS S +SS S
Sbjct: 848 EHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQS 881
Score = 44.7 bits (104), Expect = 3e-04
Identities = 72/316 (22%), Positives = 113/316 (35%), Gaps = 42/316 (13%)
Query: 367 KQETSLS-GSQYNINFQQGPSISLHSGLHHRPDKISDHS-SVKQEYTHKAGSSKHHGPIS 424
KQE S GS+ + PS SG HR K H S K + HKA + +
Sbjct: 644 KQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAE 703
Query: 425 TTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKM 484
+ K R+KRK R ++ + + + S S P +
Sbjct: 704 SG--------EKSKKRKKRK--------RKKNKSSAPADSERGPKPEPPGSGSPAPPRRR 747
Query: 485 KIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGK 544
+ ++++ +E S K + + + K ++ SS +R + + S
Sbjct: 748 RRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRS 807
Query: 545 SKHSSPHIS---RDHKEKHKEHPSS--------RHHTSSHKHSHSHSGSSSGGSKHSADG 593
S S P D H+ H S S +HS S S S S H +
Sbjct: 808 SHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSS- 866
Query: 594 IPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNH------HSKMSKSSKSSGSSSSS 647
R SSD S S SR+R + +D+ ++ HSK S S S +SS
Sbjct: 867 ------RRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSK 920
Query: 648 SSSVKQYISSHNSVFN 663
S + SS + ++
Sbjct: 921 HRSKRHKYSSSDDDYS 936
>gi|113415504 PREDICTED: similar to ribonucleic acid binding protein
S1 [Homo sapiens]
Length = 305
Score = 45.8 bits (107), Expect = 1e-04
Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 1/124 (0%)
Query: 516 KSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKH 575
KS+++ K K S E+ + G +K SS R + K H +S +S+
Sbjct: 20 KSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEK-DRGRDKTRKRHSASSGSSSTRSR 78
Query: 576 SHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMS 635
S S S S S S S+ G + S G SS SSSSSSS + H++ +
Sbjct: 79 SSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSR 138
Query: 636 KSSK 639
SK
Sbjct: 139 SKSK 142
Score = 42.7 bits (99), Expect = 0.001
Identities = 44/147 (29%), Positives = 63/147 (42%), Gaps = 12/147 (8%)
Query: 515 DKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDH-KEKHKEHPSSRHHTSSH 573
D S K++ + +K ++++ S+ K K S S+D K+K SS
Sbjct: 2 DLSGVKKKSLLGVK-ENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
Query: 574 KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSK 633
K HS SS S S + S SS G SSSS+SSR + S
Sbjct: 61 KTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSR----------SGSSS 110
Query: 634 MSKSSKSSGSSSSSSSSVKQYISSHNS 660
S+SS SS SS S S S +++ + S
Sbjct: 111 TSRSSSSSSSSGSPSPSRRRHDNRRRS 137
Score = 40.4 bits (93), Expect = 0.006
Identities = 42/158 (26%), Positives = 58/158 (36%), Gaps = 9/158 (5%)
Query: 492 EKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPH 551
+K + KE + R P P K S E+ K + K + + SS ++ G+ K H
Sbjct: 8 KKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESS-EKDRGRDKTRKRH 66
Query: 552 ISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSG-GSKHSADGIPPTVLRSPVGLSSDGI 610
+ + SS + S + S SGSSS S S S SS
Sbjct: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSS-------STSRSSSSSS 119
Query: 611 SSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSS 648
SS S S +R H N SK K + S S
Sbjct: 120 SSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPS 157
Score = 31.6 bits (70), Expect = 2.7
Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 12/132 (9%)
Query: 542 SGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSAD---GIPPTV 598
SG K S + ++K+ PS G +K S++ G T
Sbjct: 4 SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTR 63
Query: 599 LRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSH 658
R S+SS SS R + S + S + SS S SSS+SS S S
Sbjct: 64 KRH---------SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRS 114
Query: 659 NSVFNHPLPPPP 670
+S + P P
Sbjct: 115 SSSSSSSGSPSP 126
>gi|169166499 PREDICTED: similar to ribonucleic acid binding protein
S1 [Homo sapiens]
Length = 305
Score = 45.8 bits (107), Expect = 1e-04
Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 1/124 (0%)
Query: 516 KSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKH 575
KS+++ K K S E+ + G +K SS R + K H +S +S+
Sbjct: 20 KSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEK-DRGRDKTRKRHSASSGSSSTRSR 78
Query: 576 SHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMS 635
S S S S S S S+ G + S G SS SSSSSSS + H++ +
Sbjct: 79 SSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSR 138
Query: 636 KSSK 639
SK
Sbjct: 139 SKSK 142
Score = 42.7 bits (99), Expect = 0.001
Identities = 44/147 (29%), Positives = 63/147 (42%), Gaps = 12/147 (8%)
Query: 515 DKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDH-KEKHKEHPSSRHHTSSH 573
D S K++ + +K ++++ S+ K K S S+D K+K SS
Sbjct: 2 DLSGVKKKSLLGVK-ENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
Query: 574 KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSK 633
K HS SS S S + S SS G SSSS+SSR + S
Sbjct: 61 KTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSR----------SGSSS 110
Query: 634 MSKSSKSSGSSSSSSSSVKQYISSHNS 660
S+SS SS SS S S S +++ + S
Sbjct: 111 TSRSSSSSSSSGSPSPSRRRHDNRRRS 137
Score = 40.4 bits (93), Expect = 0.006
Identities = 42/158 (26%), Positives = 58/158 (36%), Gaps = 9/158 (5%)
Query: 492 EKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPH 551
+K + KE + R P P K S E+ K + K + + SS ++ G+ K H
Sbjct: 8 KKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESS-EKDRGRDKTRKRH 66
Query: 552 ISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSG-GSKHSADGIPPTVLRSPVGLSSDGI 610
+ + SS + S + S SGSSS S S S SS
Sbjct: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSS-------STSRSSSSSS 119
Query: 611 SSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSS 648
SS S S +R H N SK K + S S
Sbjct: 120 SSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPS 157
Score = 31.6 bits (70), Expect = 2.7
Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 12/132 (9%)
Query: 542 SGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSAD---GIPPTV 598
SG K S + ++K+ PS G +K S++ G T
Sbjct: 4 SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTR 63
Query: 599 LRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSH 658
R S+SS SS R + S + S + SS S SSS+SS S S
Sbjct: 64 KRH---------SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRS 114
Query: 659 NSVFNHPLPPPP 670
+S + P P
Sbjct: 115 SSSSSSSGSPSP 126
>gi|113415498 PREDICTED: similar to ribonucleic acid binding protein
S1 [Homo sapiens]
Length = 305
Score = 45.8 bits (107), Expect = 1e-04
Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 1/124 (0%)
Query: 516 KSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKH 575
KS+++ K K S E+ + G +K SS R + K H +S +S+
Sbjct: 20 KSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEK-DRGRDKTRKRHSASSGSSSTRSR 78
Query: 576 SHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMS 635
S S S S S S S+ G + S G SS SSSSSSS + H++ +
Sbjct: 79 SSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSR 138
Query: 636 KSSK 639
SK
Sbjct: 139 SKSK 142
Score = 42.7 bits (99), Expect = 0.001
Identities = 44/147 (29%), Positives = 63/147 (42%), Gaps = 12/147 (8%)
Query: 515 DKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDH-KEKHKEHPSSRHHTSSH 573
D S K++ + +K ++++ S+ K K S S+D K+K SS
Sbjct: 2 DLSGVKKKSLLGVK-ENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
Query: 574 KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSK 633
K HS SS S S + S SS G SSSS+SSR + S
Sbjct: 61 KTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSR----------SGSSS 110
Query: 634 MSKSSKSSGSSSSSSSSVKQYISSHNS 660
S+SS SS SS S S S +++ + S
Sbjct: 111 TSRSSSSSSSSGSPSPSRRRHDNRRRS 137
Score = 40.4 bits (93), Expect = 0.006
Identities = 42/158 (26%), Positives = 58/158 (36%), Gaps = 9/158 (5%)
Query: 492 EKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPH 551
+K + KE + R P P K S E+ K + K + + SS ++ G+ K H
Sbjct: 8 KKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESS-EKDRGRDKTRKRH 66
Query: 552 ISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSG-GSKHSADGIPPTVLRSPVGLSSDGI 610
+ + SS + S + S SGSSS S S S SS
Sbjct: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSS-------STSRSSSSSS 119
Query: 611 SSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSS 648
SS S S +R H N SK K + S S
Sbjct: 120 SSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPS 157
Score = 31.6 bits (70), Expect = 2.7
Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 12/132 (9%)
Query: 542 SGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSAD---GIPPTV 598
SG K S + ++K+ PS G +K S++ G T
Sbjct: 4 SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTR 63
Query: 599 LRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSH 658
R S+SS SS R + S + S + SS S SSS+SS S S
Sbjct: 64 KRH---------SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRS 114
Query: 659 NSVFNHPLPPPP 670
+S + P P
Sbjct: 115 SSSSSSSGSPSP 126
>gi|88973230 PREDICTED: similar to ribonucleic acid binding protein
S1 isoform 3 [Homo sapiens]
Length = 305
Score = 45.8 bits (107), Expect = 1e-04
Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 1/124 (0%)
Query: 516 KSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKH 575
KS+++ K K S E+ + G +K SS R + K H +S +S+
Sbjct: 20 KSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEK-DRGRDKTRKRHSASSGSSSTRSR 78
Query: 576 SHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMS 635
S S S S S S S+ G + S G SS SSSSSSS + H++ +
Sbjct: 79 SSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSR 138
Query: 636 KSSK 639
SK
Sbjct: 139 SKSK 142
Score = 42.7 bits (99), Expect = 0.001
Identities = 44/147 (29%), Positives = 63/147 (42%), Gaps = 12/147 (8%)
Query: 515 DKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDH-KEKHKEHPSSRHHTSSH 573
D S K++ + +K ++++ S+ K K S S+D K+K SS
Sbjct: 2 DLSGVKKKSLLGVK-ENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRD 60
Query: 574 KHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSK 633
K HS SS S S + S SS G SSSS+SSR + S
Sbjct: 61 KTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSR----------SGSSS 110
Query: 634 MSKSSKSSGSSSSSSSSVKQYISSHNS 660
S+SS SS SS S S S +++ + S
Sbjct: 111 TSRSSSSSSSSGSPSPSRRRHDNRRRS 137
Score = 40.4 bits (93), Expect = 0.006
Identities = 42/158 (26%), Positives = 58/158 (36%), Gaps = 9/158 (5%)
Query: 492 EKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPH 551
+K + KE + R P P K S E+ K + K + + SS ++ G+ K H
Sbjct: 8 KKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESS-EKDRGRDKTRKRH 66
Query: 552 ISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSG-GSKHSADGIPPTVLRSPVGLSSDGI 610
+ + SS + S + S SGSSS S S S SS
Sbjct: 67 SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSS-------STSRSSSSSS 119
Query: 611 SSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSS 648
SS S S +R H N SK K + S S
Sbjct: 120 SSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPS 157
Score = 31.6 bits (70), Expect = 2.7
Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 12/132 (9%)
Query: 542 SGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSAD---GIPPTV 598
SG K S + ++K+ PS G +K S++ G T
Sbjct: 4 SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTR 63
Query: 599 LRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSH 658
R S+SS SS R + S + S + SS S SSS+SS S S
Sbjct: 64 KRH---------SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRS 114
Query: 659 NSVFNHPLPPPP 670
+S + P P
Sbjct: 115 SSSSSSSGSPSP 126
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 45.8 bits (107), Expect = 1e-04
Identities = 55/215 (25%), Positives = 87/215 (40%), Gaps = 26/215 (12%)
Query: 457 IAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDK 516
+++ + H S ++SS+S + +K + K E S S KL + +
Sbjct: 1089 VSSSGSKSHHSHSSSSSSSASTSGKMK------------SSKSEGSSSSKLSSSMYSSQG 1136
Query: 517 SASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKH- 575
S+ + K +S + S +KH S K K + PSS + S K
Sbjct: 1137 SSGSSQSK------NSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPN 1190
Query: 576 -SHSHSGSSSGGSKHSA-----DGIPP-TVLRSPVGLSSDGISSSSSSSRKRLHVNDASH 628
S SHS G K ++ G PP + +SP+ S G S +SS + +
Sbjct: 1191 ISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLG 1250
Query: 629 NHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSVFN 663
+ S K+ SS S ++SSSS SS +S N
Sbjct: 1251 SSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQN 1285
Score = 41.6 bits (96), Expect = 0.003
Identities = 89/455 (19%), Positives = 152/455 (33%), Gaps = 72/455 (15%)
Query: 273 SETPLLGSSLVQNSILVDSVTGVPTNPSFQKPSTSAFPAPVPLNS----GNISVQDSHTS 328
S+ P+ ++ +++ +T P+ S P+T P P P S +S DS
Sbjct: 719 SQNPIFDVNMTADTLDTPHITPAPSQCS-TPPTTYPQPVPHPQPSIQRMVRLSSSDSIGP 777
Query: 329 DNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSIS 388
D +L+ S S+ + P R Q T + N + P
Sbjct: 778 DVTDILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTD 837
Query: 389 ---------------------LHSGLHHRPDKISDHSS--VKQEYTHKAGSSKHHGPIST 425
H G+ PD ++ S +EY ++ S G
Sbjct: 838 PADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQS---GDNDD 894
Query: 426 TPGIIPQKMSL------------DKYREKRKLETLDL-------------DVRDHYIAAQ 460
G Q ++ K++ + +T+D D+ +H+ +Q
Sbjct: 895 FKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQ 954
Query: 461 -----------VEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRI 509
+ Q + + S+S+++ P P + D K K K R
Sbjct: 955 GPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPK-RK 1013
Query: 510 PIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKH----SSPHISRDHKEKHKEHPS 565
KS S +S S S +G+S+ ++P I + + K
Sbjct: 1014 KADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVM 1073
Query: 566 SRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVND 625
+S +++ S S SSSG H + + S G S SSSS+ +
Sbjct: 1074 VGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYS 1133
Query: 626 ASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNS 660
+ + S SK+S SG SS K +SS +S
Sbjct: 1134 SQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSS 1168
Score = 40.0 bits (92), Expect = 0.008
Identities = 55/215 (25%), Positives = 79/215 (36%), Gaps = 31/215 (14%)
Query: 466 KQGQSQAASSSSVTSPIK----MKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKE 521
K G S +SS+ + K M ++ + + GS KL P+ P +
Sbjct: 1160 KHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSS 1219
Query: 522 ELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSG 581
+ K I S H S S K SS + K PSS T+S S S SG
Sbjct: 1220 KAKSPISSGSGGSHMSGTSSSSGMKSSSG-LGSSGSLSQKTPPSSNSCTASSS-SFSSSG 1277
Query: 582 SSSGGSKH---SADGIPPTVLRSPV----------GLSSDG------------ISSSSSS 616
SS S++ S+ G P+ + P G+ + G +S++SSS
Sbjct: 1278 SSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSS 1337
Query: 617 SRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSV 651
N + K KS K S+S SSV
Sbjct: 1338 HPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSV 1372
Score = 38.5 bits (88), Expect = 0.022
Identities = 59/229 (25%), Positives = 82/229 (35%), Gaps = 48/229 (20%)
Query: 514 TDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSH 573
T KE+ + ++K + +S+ SK + + K K+ P R +
Sbjct: 959 TTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTE 1018
Query: 574 KHSHSHSGS--------SSGGSKHSADG-------------IPPTVLRSPVGL------- 605
S SHS S S+GGSK IP ++ P G
Sbjct: 1019 GKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPS 1078
Query: 606 ------SSDGISSS--------SSSSRKRLHVNDASHNHHSKMSKSSKSSGS--SSSSSS 649
SS +SSS SSSS + + S+ S SSK S S SS SS
Sbjct: 1079 SHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSS 1138
Query: 650 SVKQYISSHNSVFNHPLPPPPPVT-YQVGYGHLSTLVKLDKKPVETNGP 697
Q S NS + P P+T + + G ST +K KP P
Sbjct: 1139 GSSQ---SKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNP 1184
Score = 37.7 bits (86), Expect = 0.038
Identities = 88/415 (21%), Positives = 141/415 (33%), Gaps = 66/415 (15%)
Query: 260 NQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPSFQKPSTSAFPAPVPLNSGN 319
N + KP + S P G S L + VP P K A P++SG+
Sbjct: 1183 NPSLSKPNISPSHSRPP--GGS----DKLASPMKPVPGTPPSSK-------AKSPISSGS 1229
Query: 320 ISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNI 379
S TS + M ++ +S LS + +A + S S S +Q+
Sbjct: 1230 GGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGS 1289
Query: 380 NFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKY 439
+ + PS + L DK+ HG +++ PG D
Sbjct: 1290 SKGKSPSRNKKPSLTAVIDKLK------------------HGVVTSGPG------GEDPL 1325
Query: 440 REKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKK 499
+ + T + H ++++ + Q + S S + ++ K ++ K
Sbjct: 1326 DGQMGVST---NSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESK 1382
Query: 500 EKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEG-----SGKSKHSSPHISR 554
+ +I I D + +K KV+ + SS EG + + SP IS
Sbjct: 1383 NVGSTGVAKIIISKHDGGSP----SIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISG 1438
Query: 555 D---HKEKHKEHPSSRHHTSSHKHSHSHSGSSSG-----GSKHSADGIPPTVLRSPVGLS 606
H+ H S +T + S S SGSS S S DGI P L
Sbjct: 1439 STPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRP--------LP 1490
Query: 607 SDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSV 661
+++ V D + + K S S S S K ISS S+
Sbjct: 1491 EYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWS-KSPISSDQSL 1544
Score = 37.0 bits (84), Expect = 0.065
Identities = 45/170 (26%), Positives = 62/170 (36%), Gaps = 18/170 (10%)
Query: 506 KLRIPIPP----TDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHK 561
K+ I IP K +S + VSSS S S S SS S K
Sbjct: 1062 KITIQIPKGTVMVGKPSSHSQYTSSGSVSSSG--SKSHHSHSSSSSSSASTSGKMKSSKS 1119
Query: 562 EHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRL 621
E SS +SS S SGSS + + G P + + GLSS S+ K
Sbjct: 1120 EGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPS 1179
Query: 622 HVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSVFNHPLPPPPP 671
+ + S + + S+ G S +S +K P+P PP
Sbjct: 1180 SLMNPSLSKPNISPSHSRPPGGSDKLASPMK------------PVPGTPP 1217
>gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]
Length = 738
Score = 45.8 bits (107), Expect = 1e-04
Identities = 74/261 (28%), Positives = 107/261 (40%), Gaps = 40/261 (15%)
Query: 477 SVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHS 536
S SPI IP + + K + S S K++ +D+S S ++ K + SSS S
Sbjct: 478 SAVSPIPAVIP---SPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSS 534
Query: 537 SSDEGSGKSKHSSPHISRDHKEKHKEHPSS---RHHTSSHKHSHSHSGSSSGGSKHSA-- 591
SS S ++ SSP +S HK+ + SS + + +S S S++G S SA
Sbjct: 535 SS---SLQTSLSSP-LSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKL 590
Query: 592 --------DGIPPTVLR--SPVGLSSDGISSSSSSSRKRLHVND---ASHNHHSKM---- 634
G P ++R VG SSD S S LH D ASHN S +
Sbjct: 591 EPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPS--LALHAGDLSLASHNAVSSLPLSF 648
Query: 635 --SKSSKSSGSSSSSSSSVKQYISSHNSVFNH-------PLPPPPPVTYQVGYGHLSTLV 685
S+ K SSSSS + + NSV P+P P T G S+L
Sbjct: 649 DKSEGKKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKNSSLA 708
Query: 686 KLDKKPVETNGPDANHEYSTS 706
P + P + + +T+
Sbjct: 709 LSQSSPSSISSPGHSRQKNTN 729
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.124 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,291,874
Number of Sequences: 37866
Number of extensions: 1408451
Number of successful extensions: 11643
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 135
Number of HSP's successfully gapped in prelim test: 413
Number of HSP's that attempted gapping in prelim test: 7297
Number of HSP's gapped (non-prelim): 2423
length of query: 730
length of database: 18,247,518
effective HSP length: 110
effective length of query: 620
effective length of database: 14,082,258
effective search space: 8730999960
effective search space used: 8730999960
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.