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Search of human proteins with 17921982
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17921982 heme A:farnesyltransferase [Homo sapiens]
(443 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17921982 heme A:farnesyltransferase [Homo sapiens] 906 0.0
gi|90403590 para-hydroxybenzoate-polyprenyltransferase, mitochon... 53 5e-07
gi|89886466 hematopoietic signal peptide-containing isoform 1 [H... 37 0.028
gi|33188443 microfilament and actin filament cross-linker protei... 33 0.52
gi|33188445 microfilament and actin filament cross-linker protei... 33 0.52
gi|219842343 glutamate receptor, metabotropic 5 isoform a precur... 33 0.68
gi|4504143 glutamate receptor, metabotropic 5 isoform b precurso... 33 0.68
gi|134244291 G-protein coupled receptor 37 like 1 [Homo sapiens] 33 0.68
gi|148612801 KIAA1009 protein [Homo sapiens] 31 2.6
gi|5453994 RAD21 homolog [Homo sapiens] 30 3.4
gi|223029510 echinoderm microtubule associated protein like 4 is... 30 4.4
gi|19923497 echinoderm microtubule associated protein like 4 iso... 30 4.4
gi|46276889 proteoglycan 2 preproprotein [Homo sapiens] 30 4.4
gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens] 30 4.4
gi|5729734 activator of S phase kinase [Homo sapiens] 30 5.7
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] 30 5.7
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 29 7.5
gi|52317215 olfactory receptor, family 2, subfamily T, member 10... 29 7.5
gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens] 29 9.8
gi|52351208 solute carrier family 30 (zinc transporter), member ... 29 9.8
gi|122937229 zinc finger protein 629 [Homo sapiens] 29 9.8
>gi|17921982 heme A:farnesyltransferase [Homo sapiens]
Length = 443
Score = 906 bits (2342), Expect = 0.0
Identities = 443/443 (100%), Positives = 443/443 (100%)
Query: 1 MAASPHTLSSRLLTGCVGGSVWYLERRTIQDSPHKFLHLLRNVNKQWITFQHFSFLKRMY 60
MAASPHTLSSRLLTGCVGGSVWYLERRTIQDSPHKFLHLLRNVNKQWITFQHFSFLKRMY
Sbjct: 1 MAASPHTLSSRLLTGCVGGSVWYLERRTIQDSPHKFLHLLRNVNKQWITFQHFSFLKRMY 60
Query: 61 VTQLNRSHNQQVRPKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLSLSRKPNEKELIE 120
VTQLNRSHNQQVRPKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLSLSRKPNEKELIE
Sbjct: 61 VTQLNRSHNQQVRPKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLSLSRKPNEKELIE 120
Query: 121 LEPDSVIEDSIDVGKETKEEKRWKEMKLQVYDLPGILARLSKIKLTALVVSTTAAGFALA 180
LEPDSVIEDSIDVGKETKEEKRWKEMKLQVYDLPGILARLSKIKLTALVVSTTAAGFALA
Sbjct: 121 LEPDSVIEDSIDVGKETKEEKRWKEMKLQVYDLPGILARLSKIKLTALVVSTTAAGFALA 180
Query: 181 PGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFA 240
PGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFA
Sbjct: 181 PGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFA 240
Query: 241 TCCAVPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGW 300
TCCAVPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGW
Sbjct: 241 TCCAVPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGW 300
Query: 301 TAATGSLDAGAFLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRH 360
TAATGSLDAGAFLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRH
Sbjct: 301 TAATGSLDAGAFLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRH 360
Query: 361 CLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLP 420
CLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLP
Sbjct: 361 CLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLP 420
Query: 421 LLLLLMLTCKRPSGGGDAGPPPS 443
LLLLLMLTCKRPSGGGDAGPPPS
Sbjct: 421 LLLLLMLTCKRPSGGGDAGPPPS 443
>gi|90403590 para-hydroxybenzoate-polyprenyltransferase,
mitochondrial [Homo sapiens]
Length = 384
Score = 53.1 bits (126), Expect = 5e-07
Identities = 48/150 (32%), Positives = 66/150 (44%), Gaps = 17/150 (11%)
Query: 172 TTAAGFALAPGPF-DWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQ 230
T + G A PG F DW L G L A +IN ++ +D + RT NRP+ G
Sbjct: 107 TWSIGLAAEPGCFPDWYMLSLFGTGAILMRGAGCTINDMWDQDYDKKVTRTANRPIAAGD 166
Query: 231 ISPLLAVSFATCCAVPGVAILTLGV----NPLTGALGLFNIFLYTCCYTPLKRISIANTW 286
IS +F + + G L LGV N + ALG ++ L Y +KRIS W
Sbjct: 167 IS-----TFQSFVFLGGQLTLALGVLLCLNYYSIALGAGSLLL-VITYPLMKRISY---W 217
Query: 287 VGAVVGAI---PPVMGWTAATGSLDAGAFL 313
+G ++GW+A GS D L
Sbjct: 218 PQLALGLTFNWGALLGWSAIKGSCDPSVCL 247
>gi|89886466 hematopoietic signal peptide-containing isoform 1 [Homo
sapiens]
Length = 254
Score = 37.4 bits (85), Expect = 0.028
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 347 VTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRR 406
VTHPG CR + + L + + + + TT P A A+I L A
Sbjct: 162 VTHPGGCRGHEVED-VDLELFNTSVQLQPPTTAPGPETA----AFIERLEMEQAQKAKNP 216
Query: 407 SSRRLFFCSLWHLPLLLLLMLTCKRPSGGGDAGPP 441
++ FF WH+ L ++LT RP+ G A PP
Sbjct: 217 QEQKSFFAKYWHIILGGAVLLTALRPAAPGPAPPP 251
>gi|33188443 microfilament and actin filament cross-linker protein
isoform b [Homo sapiens]
Length = 5938
Score = 33.1 bits (74), Expect = 0.52
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 14/102 (13%)
Query: 51 QHFSFLKRMYVTQ--LNRSHNQQVRPKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLS 108
+H +F++ M Q ++R R EP +PF+EK+ SG K+ + + P P LS
Sbjct: 5466 EHQTFMEEMTRKQPDVDRVTKTYKRKNIEPTHAPFIEKSRSGGRKS-LSQPTPPPMPILS 5524
Query: 109 LSRKPNEK-----------ELIELEPDSVIEDSIDVGKETKE 139
S N + L+ LE + D++D +E KE
Sbjct: 5525 QSEAKNPRINQLSARWQQVWLLALERQRKLNDALDRLEELKE 5566
>gi|33188445 microfilament and actin filament cross-linker protein
isoform a [Homo sapiens]
Length = 5430
Score = 33.1 bits (74), Expect = 0.52
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 14/102 (13%)
Query: 51 QHFSFLKRMYVTQ--LNRSHNQQVRPKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLS 108
+H +F++ M Q ++R R EP +PF+EK+ SG K+ + + P P LS
Sbjct: 4964 EHQTFMEEMTRKQPDVDRVTKTYKRKNIEPTHAPFIEKSRSGGRKS-LSQPTPPPMPILS 5022
Query: 109 LSRKPNEK-----------ELIELEPDSVIEDSIDVGKETKE 139
S N + L+ LE + D++D +E KE
Sbjct: 5023 QSEAKNPRINQLSARWQQVWLLALERQRKLNDALDRLEELKE 5064
>gi|219842343 glutamate receptor, metabotropic 5 isoform a precursor
[Homo sapiens]
Length = 1212
Score = 32.7 bits (73), Expect = 0.68
Identities = 18/67 (26%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
Query: 71 QVRPKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLSLSRKPNEKELIELEPDSVIEDS 130
+++P P + + + QA + P + P + + KP+ +EL+ L P S DS
Sbjct: 1114 EIQPLPAIEVTGGAQPAAGAQAAGDAARESPAAGPEAAAA-KPDLEELVALTPPSPFRDS 1172
Query: 131 IDVGKET 137
+D G T
Sbjct: 1173 VDSGSTT 1179
>gi|4504143 glutamate receptor, metabotropic 5 isoform b precursor
[Homo sapiens]
Length = 1180
Score = 32.7 bits (73), Expect = 0.68
Identities = 18/67 (26%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
Query: 71 QVRPKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLSLSRKPNEKELIELEPDSVIEDS 130
+++P P + + + QA + P + P + + KP+ +EL+ L P S DS
Sbjct: 1082 EIQPLPAIEVTGGAQPAAGAQAAGDAARESPAAGPEAAAA-KPDLEELVALTPPSPFRDS 1140
Query: 131 IDVGKET 137
+D G T
Sbjct: 1141 VDSGSTT 1147
>gi|134244291 G-protein coupled receptor 37 like 1 [Homo sapiens]
Length = 481
Score = 32.7 bits (73), Expect = 0.68
Identities = 50/190 (26%), Positives = 76/190 (40%), Gaps = 32/190 (16%)
Query: 163 IKLTALVVSTTAAGFALAPGPFDWPCFLLTSVGTGLASCAA--NSINQFFEVPFDSNMNR 220
I L ALVV L+ W + L S + + A + + FF +P
Sbjct: 133 IMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEI 192
Query: 221 TKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGVNPLT-GALGLFNIFLYTCCYTPLKR 279
TK R L G +S C AVP + + +LGV + ALG+ + T ++
Sbjct: 193 TKQRLL--GDVS---------CRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRP 241
Query: 280 IS--------IANTWVGAVVGAIPPVMGWTAA------TGSLDA----GAFLLGGILYSW 321
I +A WVG++ A+P ++ W A G+LD+ + L LYS
Sbjct: 242 IERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSL 301
Query: 322 QFPHFNALSW 331
+ NA W
Sbjct: 302 VMTYQNARMW 311
>gi|148612801 KIAA1009 protein [Homo sapiens]
Length = 1403
Score = 30.8 bits (68), Expect = 2.6
Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 8/83 (9%)
Query: 102 LSPPSLSLSRKPNEKELIELEPDSV--------IEDSIDVGKETKEEKRWKEMKLQVYDL 153
L +L L E E ++LE + + I I + + + K+ ++++ QV ++
Sbjct: 872 LDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEM 931
Query: 154 PGILARLSKIKLTALVVSTTAAG 176
GIL R L AL+++ +AAG
Sbjct: 932 EGILKRRYPNSLPALILAASAAG 954
>gi|5453994 RAD21 homolog [Homo sapiens]
Length = 631
Score = 30.4 bits (67), Expect = 3.4
Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 14/95 (14%)
Query: 76 PEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLS--------LSRKPNEKELIELEPDSVI 127
PEPV P Q + E+ P PP++ L K EKE + + +
Sbjct: 485 PEPVMPP----QQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEE 540
Query: 128 EDSIDVGKETKEEKRWKEMKLQVYDLPGILARLSK 162
++ G + +EE+RW + Q+ L G+ L+K
Sbjct: 541 DEDASGGDQDQEERRWNKRTQQM--LHGLQRALAK 573
>gi|223029510 echinoderm microtubule associated protein like 4
isoform b [Homo sapiens]
Length = 923
Score = 30.0 bits (66), Expect = 4.4
Identities = 21/74 (28%), Positives = 29/74 (39%), Gaps = 7/74 (9%)
Query: 74 PKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLSLSRKPNEKELIELEP-------DSV 126
P+ E VA L K ++ I P PPS L+ E+ I P +
Sbjct: 813 PQNETVADTTLTKAPVSSTESVIQSNTPTPPPSQPLNETAEEESRISSSPTLLENSLEQT 872
Query: 127 IEDSIDVGKETKEE 140
+E S D +E EE
Sbjct: 873 VEPSEDHSEEESEE 886
>gi|19923497 echinoderm microtubule associated protein like 4
isoform a [Homo sapiens]
Length = 981
Score = 30.0 bits (66), Expect = 4.4
Identities = 21/74 (28%), Positives = 29/74 (39%), Gaps = 7/74 (9%)
Query: 74 PKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLSLSRKPNEKELIELEP-------DSV 126
P+ E VA L K ++ I P PPS L+ E+ I P +
Sbjct: 871 PQNETVADTTLTKAPVSSTESVIQSNTPTPPPSQPLNETAEEESRISSSPTLLENSLEQT 930
Query: 127 IEDSIDVGKETKEE 140
+E S D +E EE
Sbjct: 931 VEPSEDHSEEESEE 944
>gi|46276889 proteoglycan 2 preproprotein [Homo sapiens]
Length = 222
Score = 30.0 bits (66), Expect = 4.4
Identities = 15/40 (37%), Positives = 20/40 (50%), Gaps = 3/40 (7%)
Query: 326 FNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRHCLALL 365
+N W + +SRGG+C+ T G RR HCL L
Sbjct: 180 WNFAYWAAHQPWSRGGHCVALCTRGGHWRRA---HCLRRL 216
>gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens]
Length = 529
Score = 30.0 bits (66), Expect = 4.4
Identities = 13/59 (22%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 245 VPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRI-SIANTWVGAVVGAIPPVMGWTA 302
+ ++LTLGV + + +Y T + + ++ W+ +++G +PP+ GW++
Sbjct: 110 ISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRAVMALVYIWLHSLIGCLPPLFGWSS 168
>gi|5729734 activator of S phase kinase [Homo sapiens]
Length = 674
Score = 29.6 bits (65), Expect = 5.7
Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 10/70 (14%)
Query: 83 FLEKTSSGQAKAEI-YEMRPLSPPSLSLSRKPNEKELIEL---------EPDSVIEDSID 132
F+E K I Y + LSP S S+ +K +KE +EL E D+ +++
Sbjct: 338 FVEYEKDTPKKKRIKYSVGSLSPVSASVLKKTEQKEKVELQHISQKDCQEDDTTVKEQNF 397
Query: 133 VGKETKEEKR 142
+ KET+E ++
Sbjct: 398 LYKETQETEK 407
>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
Length = 547
Score = 29.6 bits (65), Expect = 5.7
Identities = 15/73 (20%), Positives = 39/73 (53%)
Query: 69 NQQVRPKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLSLSRKPNEKELIELEPDSVIE 128
+Q++ P P P P EK + AE+ + + + +L +K + + ++ +P+S+++
Sbjct: 435 SQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQESAQRALQNGQKKKKGKKVKKQPNSILK 494
Query: 129 DSIDVGKETKEEK 141
+ + + +E+K
Sbjct: 495 EIKNSLRSVQEKK 507
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 29.3 bits (64), Expect = 7.5
Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 17/97 (17%)
Query: 42 NVNKQWITFQHFSFLKRMYVTQLN---RSHNQQVRP------KPEPVASPFLEKTS---- 88
N N +W F+++S R + Q RS +Q P PEP +P E +
Sbjct: 334 NPNSEW--FENYSLCHRCHKAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVA 391
Query: 89 -SGQAKA-EIYEMRPLSPPSLSLSRKPNEKELIELEP 123
GQ K + M+P P L KP K ++LEP
Sbjct: 392 CQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEP 428
>gi|52317215 olfactory receptor, family 2, subfamily T, member 10
[Homo sapiens]
Length = 312
Score = 29.3 bits (64), Expect = 7.5
Identities = 25/107 (23%), Positives = 46/107 (42%), Gaps = 23/107 (21%)
Query: 235 LAVSFATC---------CAVPGVAILTLGVNPLTGALGLFNIFLYTCC----YTPLKRIS 281
+A+SF C C VP A+L L + + L+ IF+Y CC P+ IS
Sbjct: 162 IAMSFPFCRSHEIQHFFCEVP--AVLKLSCSDTS----LYKIFMYLCCVIMLLIPVTVIS 215
Query: 282 IANTWVGAVVGAIPPVMG----WTAATGSLDAGAFLLGGILYSWQFP 324
++ ++ + + V G +T + + + G +Y++ P
Sbjct: 216 VSYYYIILTIHKMNSVEGRKKAFTTCSSHITVVSLFYGAAIYNYMLP 262
>gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens]
Length = 365
Score = 28.9 bits (63), Expect = 9.8
Identities = 23/83 (27%), Positives = 34/83 (40%), Gaps = 6/83 (7%)
Query: 63 QLNRSHNQQVRPKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLSLSRKPNEKELIELE 122
Q R Q+ P+ P A+ LEK + + L+ P R P E E E
Sbjct: 264 QTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEE----ETE 319
Query: 123 PDSVIEDSIDVGKETKEEKRWKE 145
+DS++ K T +E WK+
Sbjct: 320 AQQPFDDSLEHEKLTVDE--WKQ 340
>gi|52351208 solute carrier family 30 (zinc transporter), member 10
[Homo sapiens]
Length = 485
Score = 28.9 bits (63), Expect = 9.8
Identities = 19/70 (27%), Positives = 35/70 (50%), Gaps = 5/70 (7%)
Query: 125 SVIEDSIDVGKETKEEKRWKEMKLQVYDLPGILARLSKIKLTALVVSTTAAGFALAP--- 181
+V DS + E ++ + KE K + ++ G+L + L ++VV TA F + P
Sbjct: 211 NVAGDSFNTQNEPEDMMK-KEKKSEALNIRGVLLHVMGDALGSVVVVITAIIFYVLPLKS 269
Query: 182 -GPFDWPCFL 190
P +W C++
Sbjct: 270 EDPCNWQCYI 279
>gi|122937229 zinc finger protein 629 [Homo sapiens]
Length = 869
Score = 28.9 bits (63), Expect = 9.8
Identities = 19/70 (27%), Positives = 31/70 (44%), Gaps = 4/70 (5%)
Query: 54 SFLKRMYVTQLNRSHNQQVRPKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLSLSRKP 113
SFL R+ +T+ +H Q+ P PE + ++ + + E P S S
Sbjct: 776 SFLDRVALTRHQETHTQEKPPNPEDPPPEAVTLSTDQEGEGE----TPTPTESSSHGEGQ 831
Query: 114 NEKELIELEP 123
N K L+E +P
Sbjct: 832 NPKTLVEEKP 841
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,208,802
Number of Sequences: 37866
Number of extensions: 810316
Number of successful extensions: 2306
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2295
Number of HSP's gapped (non-prelim): 27
length of query: 443
length of database: 18,247,518
effective HSP length: 105
effective length of query: 338
effective length of database: 14,271,588
effective search space: 4823796744
effective search space used: 4823796744
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.