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Search of human proteins with 17572824
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17572824 advillin [Homo sapiens]
(819 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17572824 advillin [Homo sapiens] 1659 0.0
gi|194394237 villin 1 [Homo sapiens] 1040 0.0
gi|94721268 villin-like protein [Homo sapiens] 756 0.0
gi|162951877 scinderin isoform 1 [Homo sapiens] 685 0.0
gi|4504165 gelsolin isoform a precursor [Homo sapiens] 642 0.0
gi|38044288 gelsolin isoform b [Homo sapiens] 642 0.0
gi|189083782 gelsolin isoform c [Homo sapiens] 642 0.0
gi|189083780 gelsolin isoform c [Homo sapiens] 642 0.0
gi|189083778 gelsolin isoform b [Homo sapiens] 642 0.0
gi|189083776 gelsolin isoform b [Homo sapiens] 642 0.0
gi|189083774 gelsolin isoform b [Homo sapiens] 642 0.0
gi|189083772 gelsolin isoform b [Homo sapiens] 642 0.0
gi|14916473 scinderin isoform 2 [Homo sapiens] 453 e-127
gi|4503743 flightless I homolog [Homo sapiens] 280 5e-75
gi|63252913 gelsolin-like capping protein [Homo sapiens] 257 3e-68
gi|150417973 supervillin isoform 2 [Homo sapiens] 182 1e-45
gi|150417971 supervillin isoform 1 [Homo sapiens] 182 1e-45
gi|7662330 actin binding LIM protein family, member 3 [Homo sapi... 50 6e-06
gi|166706877 erythrocyte membrane protein band 4.9 isoform 1 [Ho... 43 0.001
gi|166706879 erythrocyte membrane protein band 4.9 isoform 1 [Ho... 43 0.001
gi|166706875 erythrocyte membrane protein band 4.9 isoform 1 [Ho... 43 0.001
gi|153792514 actin binding LIM protein family, member 2 isoform ... 43 0.001
gi|194272204 actin binding LIM protein family, member 2 isoform ... 43 0.001
gi|194272202 actin binding LIM protein family, member 2 isoform ... 43 0.001
gi|194272200 actin binding LIM protein family, member 2 isoform ... 43 0.001
gi|194272198 actin binding LIM protein family, member 2 isoform ... 43 0.001
gi|194272196 actin binding LIM protein family, member 2 isoform ... 43 0.001
gi|166706885 erythrocyte membrane protein band 4.9 isoform 3 [Ho... 42 0.003
gi|166706883 erythrocyte membrane protein band 4.9 isoform 2 [Ho... 42 0.003
gi|166706881 erythrocyte membrane protein band 4.9 isoform 2 [Ho... 42 0.003
>gi|17572824 advillin [Homo sapiens]
Length = 819
Score = 1659 bits (4295), Expect = 0.0
Identities = 819/819 (100%), Positives = 819/819 (100%)
Query: 1 MPLTSAFRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIH 60
MPLTSAFRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIH
Sbjct: 1 MPLTSAFRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIH 60
Query: 61 FWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVA 120
FWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVA
Sbjct: 61 FWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVA 120
Query: 121 SGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESN 180
SGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESN
Sbjct: 121 SGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESN 180
Query: 181 SGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDE 240
SGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDE
Sbjct: 181 SGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDE 240
Query: 241 IIDQKQKSTIMLYHISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGA 300
IIDQKQKSTIMLYHISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGA
Sbjct: 241 IIDQKQKSTIMLYHISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGA 300
Query: 301 TKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFS 360
TKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFS
Sbjct: 301 TKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFS 360
Query: 361 IGKIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYG 420
IGKIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYG
Sbjct: 361 IGKIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYG 420
Query: 421 GDCYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGT 480
GDCYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGT
Sbjct: 421 GDCYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGT 480
Query: 481 EPRHFMAIFKGKLVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSN 540
EPRHFMAIFKGKLVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSN
Sbjct: 481 EPRHFMAIFKGKLVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSN 540
Query: 541 DVFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTP 600
DVFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTP
Sbjct: 541 DVFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTP 600
Query: 601 YANDKRLQQEILDVQSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIG 660
YANDKRLQQEILDVQSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIG
Sbjct: 601 YANDKRLQQEILDVQSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIG 660
Query: 661 AEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWSAGK 720
AEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWSAGK
Sbjct: 661 AEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWSAGK 720
Query: 721 TYEQLKEELGDAAAIMRITADMKNATLSLNSNDSEPKYYPIAVLLKNQNQELPEDVNPAK 780
TYEQLKEELGDAAAIMRITADMKNATLSLNSNDSEPKYYPIAVLLKNQNQELPEDVNPAK
Sbjct: 721 TYEQLKEELGDAAAIMRITADMKNATLSLNSNDSEPKYYPIAVLLKNQNQELPEDVNPAK 780
Query: 781 KENYLSEQDFVSVFGITRGQFAALPGWKQLQMKKEKGLF 819
KENYLSEQDFVSVFGITRGQFAALPGWKQLQMKKEKGLF
Sbjct: 781 KENYLSEQDFVSVFGITRGQFAALPGWKQLQMKKEKGLF 819
>gi|194394237 villin 1 [Homo sapiens]
Length = 827
Score = 1040 bits (2690), Expect = 0.0
Identities = 500/811 (61%), Positives = 620/811 (76%), Gaps = 5/811 (0%)
Query: 14 PGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGKDSSQDEQS 73
PG+ +WRIE M++ VP S G+F++GDCY+IL+ + AS LS DIH+WIG+DSS DEQ
Sbjct: 17 PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQG 76
Query: 74 CAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKHVETNTYDV 133
AAIYTTQ+DD+L G VQHREVQ +ES+ FRGYFKQG++ ++GGVASGMKHVETN+YDV
Sbjct: 77 AAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYDV 136
Query: 134 KRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLAKD 193
+RLLHVKGKRN+ A EVEMSW SFNRGDVFLLDLGK+IIQWNGPES ERL+ M LAK+
Sbjct: 137 QRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKE 196
Query: 194 IRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEIIDQKQKSTIMLY 253
IRD+ERGGR +GV++G+ E ASP+LM+V+ LG+R +K VPD +++ K+ + LY
Sbjct: 197 IRDQERGGRTYVGVVDGENELASPKLMEVMNHVLGKRRELKAAVPDTVVEPALKAALKLY 256
Query: 254 HISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSKAL 313
H+SDS G L V EVATRPL QDLL+H+DCYILDQ G KIYVWKGK A + EK+ AMS AL
Sbjct: 257 HVSDSEGNLVVREVATRPLTQDLLSHEDCYILDQGGLKIYVWKGKKANEQEKKGAMSHAL 316
Query: 314 GFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFSIGKIAKVFQDKFD 373
FIK K YP ST VE NDGAESA+F+QLFQKW+ ++T GLGKT ++G +AKV Q KFD
Sbjct: 317 NFIKAKQYPPSTQVEVQNDGAESAVFQQLFQKWTASNRTSGLGKTHTVGSVAKVEQVKFD 376
Query: 374 VTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVN 433
T +H KP+VAAQ++MVDDG+G+V+VWRIENLELVPV+ +W G FYGGDCYL+LYTY +
Sbjct: 377 ATSMHVKPQVAAQQKMVDDGSGEVQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIG 436
Query: 434 GKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGKL 493
K H++LY+WQG ASQDE+ ASAYQAV +D++++G VQ+RV MG EP H M+IFKG++
Sbjct: 437 EKQHYLLYVWQGSQASQDEITASAYQAVILDQKYNGEPVQIRVPMGKEPPHLMSIFKGRM 496
Query: 494 VIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYL 553
V+++GGTSR N E P RLFQ+ G +NTKA EVPA A+ LNSNDVF+L+TQ+ YL
Sbjct: 497 VVYQGGTSRTNNLETGPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYL 556
Query: 554 WYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTPYANDKRLQQEILD 613
W GKG SGDER MAK +A + + V EGQEPA FW LGGK PYAN KRLQ+E L
Sbjct: 557 WCGKGCSGDEREMAKMVADTISRTEKQVVVEGQEPANFWMALGGKAPYANTKRLQEENLV 616
Query: 614 VQSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKESALA 673
+ RLFECSNKTG+F+ TEI DF QDDL DV LLD WDQVF WIG AN EK++A
Sbjct: 617 ITPRLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAAAT 676
Query: 674 TAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWSAGKTYEQLKEELGDAA 733
TAQ+YL THPSGRDP+TPI+++KQG EPP FTGWFLAWDP WS K+YE LK ELG++
Sbjct: 677 TAQEYLKTHPSGRDPETPIIVVKQGHEPPTFTGWFLAWDPFKWSNTKSYEDLKAELGNSR 736
Query: 734 AIMRITADM---KNATLSLNSNDSEP--KYYPIAVLLKNQNQELPEDVNPAKKENYLSEQ 788
+ITA++ K + NSN S +P+ L+ +ELPE V+P++KE +LS +
Sbjct: 737 DWSQITAEVTSPKVDVFNANSNLSSGPLPIFPLEQLVNKPVEELPEGVDPSRKEEHLSIE 796
Query: 789 DFVSVFGITRGQFAALPGWKQLQMKKEKGLF 819
DF FG+T F+ALP WKQ +KKEKGLF
Sbjct: 797 DFTQAFGMTPAAFSALPRWKQQNLKKEKGLF 827
Score = 119 bits (297), Expect = 1e-26
Identities = 119/420 (28%), Positives = 179/420 (42%), Gaps = 48/420 (11%)
Query: 8 RAVDNDPGII-VWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGKD 66
+ VD+ G + VWRIE +EL V G+FY GDCY++L T + ++ W G
Sbjct: 391 KMVDDGSGEVQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQHYLLYVWQGSQ 450
Query: 67 SSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKHV 126
+SQDE + +A LD G PVQ R E FK ++ QGG S ++
Sbjct: 451 ASQDEITASAYQAVILDQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGG-TSRTNNL 509
Query: 127 ETNTYDVKRLLHVK--GKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGER 184
ET RL V+ G N +A EV + N DVF+L W G + ER
Sbjct: 510 ETG--PSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGCSGDER 567
Query: 185 LKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEIIDQ 244
A ++A I E+ V+EG + A LG ++ T + ++
Sbjct: 568 EMAKMVADTISRTEKQ-----VVVEGQEPAN-------FWMALGGKAPYANT--KRLQEE 613
Query: 245 KQKSTIMLYHISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKAE 304
T L+ S+ G+ TE+ QD L DD ++LD +++ W GK A + E
Sbjct: 614 NLVITPRLFECSNKTGRFLATEIP--DFNQDDLEEDDVFLLD-VWDQVFFWIGKHANEEE 670
Query: 305 KQAAMSKALGFIKMKSYPSSTNVET----VNDGAESAMFKQLFQKW---------SVKDQ 351
K+AA + A + +K++PS + ET V G E F F W S +D
Sbjct: 671 KKAAATTAQEY--LKTHPSGRDPETPIIVVKQGHEPPTFTGWFLAWDPFKWSNTKSYEDL 728
Query: 352 TMGLGKTFSIGKIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVE 411
LG + +D +T T P+V + +G + ++ +E L PVE
Sbjct: 729 KAELGNS----------RDWSQITAEVTSPKVDVFNANSNLSSGPLPIFPLEQLVNKPVE 778
>gi|94721268 villin-like protein [Homo sapiens]
Length = 856
Score = 756 bits (1952), Expect = 0.0
Identities = 385/853 (45%), Positives = 554/853 (64%), Gaps = 57/853 (6%)
Query: 15 GIIVWRIEKMELALVPVSAHGNFYEGDCYVIL---STRRVASLLSQDIHFWIGKDSSQDE 71
G+ +W E ++ VP A+GNF+E CYVIL + + S D+H+W+GK + +
Sbjct: 13 GLHIWISENRKMVPVPEGAYGNFFEEHCYVILHVPQSPKATQGASSDLHYWVGKQAGAEA 72
Query: 72 QSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKHVETNTY 131
Q A + +L D LGG V HRE Q HESD F YF+ GIIY++GG+AS +KHVETN +
Sbjct: 73 QGAAEAFQQRLQDELGGQTVLHREAQGHESDCFCSYFRPGIIYRKGGLASDLKHVETNLF 132
Query: 132 DVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLA 191
+++RLLH+KG++++ ATEVE+SW+SFN+GD+FLLDLGK++IQWNGP+++ E+ + + L
Sbjct: 133 NIQRLLHIKGRKHVSATEVELSWNSFNKGDIFLLDLGKMMIQWNGPKTSISEKARGLALT 192
Query: 192 KDIRDRERGG-RAEIGVIEGDKEAASPELMKVLQDTLGRR-SIIKPTVPDEIIDQKQKST 249
+RDRERGG RA+IGV+ D EA +P+LM++++ LGRR ++ P + I+Q QK+
Sbjct: 193 YSLRDRERGGGRAQIGVV--DDEAKAPDLMQIMEAVLGRRVGSLRAATPSKDINQLQKAN 250
Query: 250 IMLYHISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKAEKQAAM 309
+ LYH+ + L V E+AT PL QDLL +D YILDQ G KIYVW+G+ ++ E++AA
Sbjct: 251 VRLYHVYEKGKDLVVLELATPPLTQDLLQEEDFYILDQGGFKIYVWQGRMSSLQERKAAF 310
Query: 310 SKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFSIGKIAKVFQ 369
S+A+GFI+ K YP+ TNVE VNDGAESA FKQLF+ WS K + + +G K
Sbjct: 311 SRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWSEKRR-----RNQKLGGRDKSIH 365
Query: 370 DKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGDCYLVLYT 429
K DV LHT+P++AAQ RMVDDG+GKVEVW I++L PV+ + +G G+CYLVLYT
Sbjct: 366 VKLDVGKLHTQPKLAAQLRMVDDGSGKVEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYT 425
Query: 430 YEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIF 489
Y+ G+ +ILY+WQG A+ DE+ A A E+D + G VQ V MG+EP HF+AIF
Sbjct: 426 YQRLGRVQYILYLWQGHQATADEIEALNSNAEELDVMYGGVLVQEHVTMGSEPPHFLAIF 485
Query: 490 KGKLVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQA 549
+G+LVIF+ G + RLFQ+ G D NT+ +EVPA ASSLNS+D+FLL T +
Sbjct: 486 QGQLVIFQERAGHHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTAS 545
Query: 550 EHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTPYANDKRLQQ 609
YLW+GKG +GD+R MA+ + +++ +E TV EGQEP FW+ LGG+ PY ++KRL +
Sbjct: 546 VCYLWFGKGCNGDQREMARVVVTVISRKNEETVLEGQEPPHFWEALGGRAPYPSNKRLPE 605
Query: 610 EILDVQSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKE 669
E+ Q RLFECS+ G V+ E+ F+Q+DL+ D+MLLDTW ++FLW+G A+E +
Sbjct: 606 EVPSFQPRLFECSSHMGCLVLAEVGFFSQEDLDKYDIMLLDTWQEIFLWLGEA--ASEWK 663
Query: 670 SALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWSAGKTYEQLKEEL 729
A+A Q+YL THP+GR P TPI+++KQG EPP F GWF WDP W++ +++++ +
Sbjct: 664 EAVAWGQEYLKTHPAGRSPATPIVLVKQGHEPPTFIGWFFTWDPYKWTSHPSHKEVVDGS 723
Query: 730 GDAAA-IMRITADMKNATL-------------------SLNSNDSEPKYYPIAV------ 763
AA+ I ITA++ N L S +S++++ P +
Sbjct: 724 PAAASTISEITAEVNNLRLSRWPGNGRAGAVALQALKGSQDSSENDLVRSPKSAGSRTSS 783
Query: 764 -----------------LLKNQNQELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALPG 806
L+ ++LPE V+PA++E YLS+ DF +FG ++ +F ++
Sbjct: 784 SVSSTSATINGGLRREQLMHQAVEDLPEGVDPARREFYLSDSDFQDIFGKSKEEFYSMAT 843
Query: 807 WKQLQMKKEKGLF 819
W+Q Q KK+ G F
Sbjct: 844 WRQRQEKKQLGFF 856
Score = 79.0 bits (193), Expect = 2e-14
Identities = 86/351 (24%), Positives = 141/351 (40%), Gaps = 31/351 (8%)
Query: 3 LTSAFRAVDNDPGII-VWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHF 61
L + R VD+ G + VW I+ + V HG G+CY++L T + + ++
Sbjct: 379 LAAQLRMVDDGSGKVEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRVQYILYL 438
Query: 62 WIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVAS 121
W G ++ DE +LD GG VQ E F F+ ++ Q
Sbjct: 439 WQGHQATADEIEALNSNAEELDVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVIFQERAG- 497
Query: 122 GMKHVETNTYDVKRLLHVKG--KRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPES 179
H + + RL V+G N R EV S N D+FLL V W G
Sbjct: 498 --HHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGKGC 555
Query: 180 NSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPD 239
N +R A ++ I + E V+EG + P + L S +P+
Sbjct: 556 NGDQREMARVVVTVISRKN-----EETVLEGQE---PPHFWEALGGRAPYPS--NKRLPE 605
Query: 240 EIIDQKQKSTIMLYHISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKG 299
E+ + + L+ S G L + EV Q+ L+ D +LD + +I++W G+
Sbjct: 606 EVPSFQPR----LFECSSHMGCLVLAEVGF--FSQEDLDKYDIMLLD-TWQEIFLWLGEA 658
Query: 300 ATKAEKQAAMSKALGFIKMKSYPS----STNVETVNDGAESAMFKQLFQKW 346
A++ ++ A + +K++P+ +T + V G E F F W
Sbjct: 659 ASEWKEAVAWGQEY----LKTHPAGRSPATPIVLVKQGHEPPTFIGWFFTW 705
Score = 76.6 bits (187), Expect = 8e-14
Identities = 79/341 (23%), Positives = 133/341 (39%), Gaps = 29/341 (8%)
Query: 395 GKVEVWRIENLELVPVEYQWYGFFYGGDCYLVLY---TYEVNGKPHHILYIWQGRHASQD 451
G + +W EN ++VPV YG F+ CY++L+ + + L+ W G+ A +
Sbjct: 12 GGLHIWISENRKMVPVPEGAYGNFFEEHCYVILHVPQSPKATQGASSDLHYWVGKQAGAE 71
Query: 452 ELAASAYQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEGGTSRKGNAEPDPP 511
A+ + + G V R G E F + F+ ++ +GG + +
Sbjct: 72 AQGAAEAFQQRLQDELGGQTVLHREAQGHESDCFCSYFRPGIIYRKGGLA---SDLKHVE 128
Query: 512 VRLFQI----HGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMA 567
LF I H + + A EV +S N D+FLL W G +S E+A
Sbjct: 129 TNLFNIQRLLHIKGRKHVSATEVELSWNSFNKGDIFLLDLGKMMIQWNGPKTSISEKARG 188
Query: 568 KELASLLCD----GSENTVAEGQEPAEFWDLLG----------GKTPYANDKRLQQEILD 613
L L D G + + A+ DL+ G A + ++
Sbjct: 189 LALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGRRVGSLRAATPSKDINQLQK 248
Query: 614 VQSRLFECSNKTGQFVVTEIT--DFTQDDLNPTDVMLLDTWD-QVFLWIGAEANATEKES 670
RL+ K VV E+ TQD L D +LD ++++W G ++ E+++
Sbjct: 249 ANVRLYHVYEKGKDLVVLELATPPLTQDLLQEEDFYILDQGGFKIYVWQGRMSSLQERKA 308
Query: 671 ALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAW 711
A + A ++ G T + ++ G E F F W
Sbjct: 309 AFSRAVGFIQA--KGYPTYTNVEVVNDGAESAAFKQLFRTW 347
>gi|162951877 scinderin isoform 1 [Homo sapiens]
Length = 715
Score = 685 bits (1768), Expect = 0.0
Identities = 355/721 (49%), Positives = 473/721 (65%), Gaps = 26/721 (3%)
Query: 7 FRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGKD 66
F G+ VWRIEK+EL VP SAHG+FY GD Y++L T + + + +HFW+GK+
Sbjct: 10 FARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWLGKE 69
Query: 67 SSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKHV 126
SQDE + AAI+T Q+DDYLGG PVQ+RE+Q +ES+ F YFK G+ YK GGVASG+ HV
Sbjct: 70 CSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGLNHV 129
Query: 127 ETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLK 186
TN KRLLHVKG+R +RATEV +SWDSFN+GD F++DLG I QW G N ERLK
Sbjct: 130 LTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLK 189
Query: 187 AMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDE------ 240
A +A IR ER GR+E+ V+E E + EL+KVL + KP +PD
Sbjct: 190 ANQVATGIRYNERKGRSELIVVEEGSEPS--ELIKVLGE--------KPELPDGGDDDDI 239
Query: 241 IIDQKQKSTIMLYHISDSAGQLAVTEVA-TRPLVQDLLNHDDCYILDQSGTK-IYVWKGK 298
I D + LY +SD++G + VT VA P +L ++C+ILD K I+VWKGK
Sbjct: 240 IADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGK 299
Query: 299 GATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKT 358
A E++AAM A F++ +Y +T ++ + +G E+ +FKQ F+ W KDQ+ G GK
Sbjct: 300 DANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKV 359
Query: 359 FSIGKIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFF 418
+ K+A++ Q FD + LH+ P++AAQ MVDDG+GKVE+WR+EN + V+ YG F
Sbjct: 360 YVTEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEF 419
Query: 419 YGGDCYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRM 478
YGGDCY++LYTY I+Y WQG +A++DEL SA+ V++DR G AVQ+RV
Sbjct: 420 YGGDCYIILYTYPRG----QIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQ 475
Query: 479 GTEPRHFMAIFKGK-LVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSL 537
G EP H +++FK K L+I++ GTS+KG P PP RLFQ+ N S T+ VEV A+SL
Sbjct: 476 GKEPVHLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSL 535
Query: 538 NSNDVFLLR-TQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLG 596
NSNDVF+L+ Q Y+W GKG+S +E A+ +AS+L + EG+EP EFW+ LG
Sbjct: 536 NSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVASVL-KCKTLRIQEGEEPEEFWNSLG 594
Query: 597 GKTPYANDKRLQQEILDVQSRLFECSNKTGQFVVTEIT-DFTQDDLNPTDVMLLDTWDQV 655
GK Y L+ + D RL+ CSNKTG+FV+ EI +FTQDDL DVMLLD W+Q+
Sbjct: 595 GKKDYQTSPLLETQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQI 654
Query: 656 FLWIGAEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNI 715
F+WIG +AN EK+ +L +A+ YL T PSGRD TPI+IIKQG EPP FTGWFL WD +
Sbjct: 655 FIWIGKDANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSK 714
Query: 716 W 716
W
Sbjct: 715 W 715
>gi|4504165 gelsolin isoform a precursor [Homo sapiens]
Length = 782
Score = 642 bits (1655), Expect = 0.0
Identities = 339/718 (47%), Positives = 442/718 (61%), Gaps = 14/718 (1%)
Query: 7 FRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVAS-LLSQDIHFWIGK 65
F +PG+ +WR+EK +L VP + +G+F+ GD YVIL T ++ + L D+H+W+G
Sbjct: 59 FLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGN 118
Query: 66 DSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKH 125
+ SQDE AAI+T QLDDYL G VQHREVQ ES TF GYFK G+ YK+GGVASG KH
Sbjct: 119 ECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKH 178
Query: 126 VETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERL 185
V N V+RL VKG+R +RATEV +SW+SFN GD F+LDLG I QW G SN ERL
Sbjct: 179 VVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERL 238
Query: 186 KAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEII-DQ 244
KA ++K IRD ER GRA + V E E PE M LG + + D D
Sbjct: 239 KATQVSKGIRDNERSGRARVHVSE---EGTEPEAML---QVLGPKPALPAGTEDTAKEDA 292
Query: 245 KQKSTIMLYHISDSAGQLAVTEVATR-PLVQDLLNHDDCYILDQSGT-KIYVWKGKGATK 302
+ LY +S+ AG ++V+ VA P Q L +DC+ILD KI+VWKGK A
Sbjct: 293 ANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANT 352
Query: 303 AEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFSIG 362
E++AA+ A FI YP T V + +G E+ +FKQ F+ W DQT GLG ++
Sbjct: 353 EERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSS 412
Query: 363 KIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGD 422
IA V + FD LHT +AAQ M DDG G+ ++WRIE VPV+ YG FYGGD
Sbjct: 413 HIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGD 472
Query: 423 CYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEP 482
Y++LY Y G+ I+Y WQG ++QDE+AASA ++D + G VQ RV G EP
Sbjct: 473 SYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 532
Query: 483 RHFMAIFKGK-LVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND 541
H M++F GK ++I++GGTSR+G RLFQ+ N T+AVEV A +LNSND
Sbjct: 533 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 592
Query: 542 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTPY 601
F+L+T + YLW G G+S E+ A+EL +L VAEG EP FW+ LGGK Y
Sbjct: 593 AFVLKTPSAAYLWVGTGASEAEKTGAQELLRVL-RAQPVQVAEGSEPDGFWEALGGKAAY 651
Query: 602 ANDKRLQQEILDVQ-SRLFECSNKTGQFVVTEIT-DFTQDDLNPTDVMLLDTWDQVFLWI 659
RL+ + +D RLF CSNK G+FV+ E+ + Q+DL DVMLLDTWDQVF+W+
Sbjct: 652 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 711
Query: 660 GAEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWS 717
G ++ EK AL +A++Y+ T P+ RD TPI ++KQGFEPP F GWFL WD + WS
Sbjct: 712 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWS 769
>gi|38044288 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 642 bits (1655), Expect = 0.0
Identities = 339/718 (47%), Positives = 442/718 (61%), Gaps = 14/718 (1%)
Query: 7 FRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVAS-LLSQDIHFWIGK 65
F +PG+ +WR+EK +L VP + +G+F+ GD YVIL T ++ + L D+H+W+G
Sbjct: 8 FLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGN 67
Query: 66 DSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKH 125
+ SQDE AAI+T QLDDYL G VQHREVQ ES TF GYFK G+ YK+GGVASG KH
Sbjct: 68 ECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKH 127
Query: 126 VETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERL 185
V N V+RL VKG+R +RATEV +SW+SFN GD F+LDLG I QW G SN ERL
Sbjct: 128 VVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERL 187
Query: 186 KAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEII-DQ 244
KA ++K IRD ER GRA + V E E PE M LG + + D D
Sbjct: 188 KATQVSKGIRDNERSGRARVHVSE---EGTEPEAML---QVLGPKPALPAGTEDTAKEDA 241
Query: 245 KQKSTIMLYHISDSAGQLAVTEVATR-PLVQDLLNHDDCYILDQSGT-KIYVWKGKGATK 302
+ LY +S+ AG ++V+ VA P Q L +DC+ILD KI+VWKGK A
Sbjct: 242 ANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANT 301
Query: 303 AEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFSIG 362
E++AA+ A FI YP T V + +G E+ +FKQ F+ W DQT GLG ++
Sbjct: 302 EERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSS 361
Query: 363 KIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGD 422
IA V + FD LHT +AAQ M DDG G+ ++WRIE VPV+ YG FYGGD
Sbjct: 362 HIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGD 421
Query: 423 CYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEP 482
Y++LY Y G+ I+Y WQG ++QDE+AASA ++D + G VQ RV G EP
Sbjct: 422 SYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 481
Query: 483 RHFMAIFKGK-LVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND 541
H M++F GK ++I++GGTSR+G RLFQ+ N T+AVEV A +LNSND
Sbjct: 482 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 541
Query: 542 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTPY 601
F+L+T + YLW G G+S E+ A+EL +L VAEG EP FW+ LGGK Y
Sbjct: 542 AFVLKTPSAAYLWVGTGASEAEKTGAQELLRVL-RAQPVQVAEGSEPDGFWEALGGKAAY 600
Query: 602 ANDKRLQQEILDVQ-SRLFECSNKTGQFVVTEIT-DFTQDDLNPTDVMLLDTWDQVFLWI 659
RL+ + +D RLF CSNK G+FV+ E+ + Q+DL DVMLLDTWDQVF+W+
Sbjct: 601 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 660
Query: 660 GAEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWS 717
G ++ EK AL +A++Y+ T P+ RD TPI ++KQGFEPP F GWFL WD + WS
Sbjct: 661 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWS 718
>gi|189083782 gelsolin isoform c [Homo sapiens]
Length = 742
Score = 642 bits (1655), Expect = 0.0
Identities = 339/718 (47%), Positives = 442/718 (61%), Gaps = 14/718 (1%)
Query: 7 FRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVAS-LLSQDIHFWIGK 65
F +PG+ +WR+EK +L VP + +G+F+ GD YVIL T ++ + L D+H+W+G
Sbjct: 19 FLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGN 78
Query: 66 DSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKH 125
+ SQDE AAI+T QLDDYL G VQHREVQ ES TF GYFK G+ YK+GGVASG KH
Sbjct: 79 ECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKH 138
Query: 126 VETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERL 185
V N V+RL VKG+R +RATEV +SW+SFN GD F+LDLG I QW G SN ERL
Sbjct: 139 VVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERL 198
Query: 186 KAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEII-DQ 244
KA ++K IRD ER GRA + V E E PE M LG + + D D
Sbjct: 199 KATQVSKGIRDNERSGRARVHVSE---EGTEPEAML---QVLGPKPALPAGTEDTAKEDA 252
Query: 245 KQKSTIMLYHISDSAGQLAVTEVATR-PLVQDLLNHDDCYILDQSGT-KIYVWKGKGATK 302
+ LY +S+ AG ++V+ VA P Q L +DC+ILD KI+VWKGK A
Sbjct: 253 ANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANT 312
Query: 303 AEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFSIG 362
E++AA+ A FI YP T V + +G E+ +FKQ F+ W DQT GLG ++
Sbjct: 313 EERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSS 372
Query: 363 KIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGD 422
IA V + FD LHT +AAQ M DDG G+ ++WRIE VPV+ YG FYGGD
Sbjct: 373 HIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGD 432
Query: 423 CYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEP 482
Y++LY Y G+ I+Y WQG ++QDE+AASA ++D + G VQ RV G EP
Sbjct: 433 SYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 492
Query: 483 RHFMAIFKGK-LVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND 541
H M++F GK ++I++GGTSR+G RLFQ+ N T+AVEV A +LNSND
Sbjct: 493 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 552
Query: 542 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTPY 601
F+L+T + YLW G G+S E+ A+EL +L VAEG EP FW+ LGGK Y
Sbjct: 553 AFVLKTPSAAYLWVGTGASEAEKTGAQELLRVL-RAQPVQVAEGSEPDGFWEALGGKAAY 611
Query: 602 ANDKRLQQEILDVQ-SRLFECSNKTGQFVVTEIT-DFTQDDLNPTDVMLLDTWDQVFLWI 659
RL+ + +D RLF CSNK G+FV+ E+ + Q+DL DVMLLDTWDQVF+W+
Sbjct: 612 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 671
Query: 660 GAEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWS 717
G ++ EK AL +A++Y+ T P+ RD TPI ++KQGFEPP F GWFL WD + WS
Sbjct: 672 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWS 729
>gi|189083780 gelsolin isoform c [Homo sapiens]
Length = 742
Score = 642 bits (1655), Expect = 0.0
Identities = 339/718 (47%), Positives = 442/718 (61%), Gaps = 14/718 (1%)
Query: 7 FRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVAS-LLSQDIHFWIGK 65
F +PG+ +WR+EK +L VP + +G+F+ GD YVIL T ++ + L D+H+W+G
Sbjct: 19 FLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGN 78
Query: 66 DSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKH 125
+ SQDE AAI+T QLDDYL G VQHREVQ ES TF GYFK G+ YK+GGVASG KH
Sbjct: 79 ECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKH 138
Query: 126 VETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERL 185
V N V+RL VKG+R +RATEV +SW+SFN GD F+LDLG I QW G SN ERL
Sbjct: 139 VVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERL 198
Query: 186 KAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEII-DQ 244
KA ++K IRD ER GRA + V E E PE M LG + + D D
Sbjct: 199 KATQVSKGIRDNERSGRARVHVSE---EGTEPEAML---QVLGPKPALPAGTEDTAKEDA 252
Query: 245 KQKSTIMLYHISDSAGQLAVTEVATR-PLVQDLLNHDDCYILDQSGT-KIYVWKGKGATK 302
+ LY +S+ AG ++V+ VA P Q L +DC+ILD KI+VWKGK A
Sbjct: 253 ANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANT 312
Query: 303 AEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFSIG 362
E++AA+ A FI YP T V + +G E+ +FKQ F+ W DQT GLG ++
Sbjct: 313 EERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSS 372
Query: 363 KIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGD 422
IA V + FD LHT +AAQ M DDG G+ ++WRIE VPV+ YG FYGGD
Sbjct: 373 HIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGD 432
Query: 423 CYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEP 482
Y++LY Y G+ I+Y WQG ++QDE+AASA ++D + G VQ RV G EP
Sbjct: 433 SYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 492
Query: 483 RHFMAIFKGK-LVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND 541
H M++F GK ++I++GGTSR+G RLFQ+ N T+AVEV A +LNSND
Sbjct: 493 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 552
Query: 542 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTPY 601
F+L+T + YLW G G+S E+ A+EL +L VAEG EP FW+ LGGK Y
Sbjct: 553 AFVLKTPSAAYLWVGTGASEAEKTGAQELLRVL-RAQPVQVAEGSEPDGFWEALGGKAAY 611
Query: 602 ANDKRLQQEILDVQ-SRLFECSNKTGQFVVTEIT-DFTQDDLNPTDVMLLDTWDQVFLWI 659
RL+ + +D RLF CSNK G+FV+ E+ + Q+DL DVMLLDTWDQVF+W+
Sbjct: 612 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 671
Query: 660 GAEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWS 717
G ++ EK AL +A++Y+ T P+ RD TPI ++KQGFEPP F GWFL WD + WS
Sbjct: 672 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWS 729
>gi|189083778 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 642 bits (1655), Expect = 0.0
Identities = 339/718 (47%), Positives = 442/718 (61%), Gaps = 14/718 (1%)
Query: 7 FRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVAS-LLSQDIHFWIGK 65
F +PG+ +WR+EK +L VP + +G+F+ GD YVIL T ++ + L D+H+W+G
Sbjct: 8 FLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGN 67
Query: 66 DSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKH 125
+ SQDE AAI+T QLDDYL G VQHREVQ ES TF GYFK G+ YK+GGVASG KH
Sbjct: 68 ECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKH 127
Query: 126 VETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERL 185
V N V+RL VKG+R +RATEV +SW+SFN GD F+LDLG I QW G SN ERL
Sbjct: 128 VVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERL 187
Query: 186 KAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEII-DQ 244
KA ++K IRD ER GRA + V E E PE M LG + + D D
Sbjct: 188 KATQVSKGIRDNERSGRARVHVSE---EGTEPEAML---QVLGPKPALPAGTEDTAKEDA 241
Query: 245 KQKSTIMLYHISDSAGQLAVTEVATR-PLVQDLLNHDDCYILDQSGT-KIYVWKGKGATK 302
+ LY +S+ AG ++V+ VA P Q L +DC+ILD KI+VWKGK A
Sbjct: 242 ANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANT 301
Query: 303 AEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFSIG 362
E++AA+ A FI YP T V + +G E+ +FKQ F+ W DQT GLG ++
Sbjct: 302 EERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSS 361
Query: 363 KIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGD 422
IA V + FD LHT +AAQ M DDG G+ ++WRIE VPV+ YG FYGGD
Sbjct: 362 HIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGD 421
Query: 423 CYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEP 482
Y++LY Y G+ I+Y WQG ++QDE+AASA ++D + G VQ RV G EP
Sbjct: 422 SYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 481
Query: 483 RHFMAIFKGK-LVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND 541
H M++F GK ++I++GGTSR+G RLFQ+ N T+AVEV A +LNSND
Sbjct: 482 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 541
Query: 542 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTPY 601
F+L+T + YLW G G+S E+ A+EL +L VAEG EP FW+ LGGK Y
Sbjct: 542 AFVLKTPSAAYLWVGTGASEAEKTGAQELLRVL-RAQPVQVAEGSEPDGFWEALGGKAAY 600
Query: 602 ANDKRLQQEILDVQ-SRLFECSNKTGQFVVTEIT-DFTQDDLNPTDVMLLDTWDQVFLWI 659
RL+ + +D RLF CSNK G+FV+ E+ + Q+DL DVMLLDTWDQVF+W+
Sbjct: 601 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 660
Query: 660 GAEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWS 717
G ++ EK AL +A++Y+ T P+ RD TPI ++KQGFEPP F GWFL WD + WS
Sbjct: 661 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWS 718
>gi|189083776 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 642 bits (1655), Expect = 0.0
Identities = 339/718 (47%), Positives = 442/718 (61%), Gaps = 14/718 (1%)
Query: 7 FRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVAS-LLSQDIHFWIGK 65
F +PG+ +WR+EK +L VP + +G+F+ GD YVIL T ++ + L D+H+W+G
Sbjct: 8 FLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGN 67
Query: 66 DSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKH 125
+ SQDE AAI+T QLDDYL G VQHREVQ ES TF GYFK G+ YK+GGVASG KH
Sbjct: 68 ECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKH 127
Query: 126 VETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERL 185
V N V+RL VKG+R +RATEV +SW+SFN GD F+LDLG I QW G SN ERL
Sbjct: 128 VVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERL 187
Query: 186 KAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEII-DQ 244
KA ++K IRD ER GRA + V E E PE M LG + + D D
Sbjct: 188 KATQVSKGIRDNERSGRARVHVSE---EGTEPEAML---QVLGPKPALPAGTEDTAKEDA 241
Query: 245 KQKSTIMLYHISDSAGQLAVTEVATR-PLVQDLLNHDDCYILDQSGT-KIYVWKGKGATK 302
+ LY +S+ AG ++V+ VA P Q L +DC+ILD KI+VWKGK A
Sbjct: 242 ANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANT 301
Query: 303 AEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFSIG 362
E++AA+ A FI YP T V + +G E+ +FKQ F+ W DQT GLG ++
Sbjct: 302 EERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSS 361
Query: 363 KIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGD 422
IA V + FD LHT +AAQ M DDG G+ ++WRIE VPV+ YG FYGGD
Sbjct: 362 HIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGD 421
Query: 423 CYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEP 482
Y++LY Y G+ I+Y WQG ++QDE+AASA ++D + G VQ RV G EP
Sbjct: 422 SYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 481
Query: 483 RHFMAIFKGK-LVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND 541
H M++F GK ++I++GGTSR+G RLFQ+ N T+AVEV A +LNSND
Sbjct: 482 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 541
Query: 542 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTPY 601
F+L+T + YLW G G+S E+ A+EL +L VAEG EP FW+ LGGK Y
Sbjct: 542 AFVLKTPSAAYLWVGTGASEAEKTGAQELLRVL-RAQPVQVAEGSEPDGFWEALGGKAAY 600
Query: 602 ANDKRLQQEILDVQ-SRLFECSNKTGQFVVTEIT-DFTQDDLNPTDVMLLDTWDQVFLWI 659
RL+ + +D RLF CSNK G+FV+ E+ + Q+DL DVMLLDTWDQVF+W+
Sbjct: 601 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 660
Query: 660 GAEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWS 717
G ++ EK AL +A++Y+ T P+ RD TPI ++KQGFEPP F GWFL WD + WS
Sbjct: 661 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWS 718
>gi|189083774 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 642 bits (1655), Expect = 0.0
Identities = 339/718 (47%), Positives = 442/718 (61%), Gaps = 14/718 (1%)
Query: 7 FRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVAS-LLSQDIHFWIGK 65
F +PG+ +WR+EK +L VP + +G+F+ GD YVIL T ++ + L D+H+W+G
Sbjct: 8 FLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGN 67
Query: 66 DSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKH 125
+ SQDE AAI+T QLDDYL G VQHREVQ ES TF GYFK G+ YK+GGVASG KH
Sbjct: 68 ECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKH 127
Query: 126 VETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERL 185
V N V+RL VKG+R +RATEV +SW+SFN GD F+LDLG I QW G SN ERL
Sbjct: 128 VVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERL 187
Query: 186 KAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEII-DQ 244
KA ++K IRD ER GRA + V E E PE M LG + + D D
Sbjct: 188 KATQVSKGIRDNERSGRARVHVSE---EGTEPEAML---QVLGPKPALPAGTEDTAKEDA 241
Query: 245 KQKSTIMLYHISDSAGQLAVTEVATR-PLVQDLLNHDDCYILDQSGT-KIYVWKGKGATK 302
+ LY +S+ AG ++V+ VA P Q L +DC+ILD KI+VWKGK A
Sbjct: 242 ANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANT 301
Query: 303 AEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFSIG 362
E++AA+ A FI YP T V + +G E+ +FKQ F+ W DQT GLG ++
Sbjct: 302 EERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSS 361
Query: 363 KIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGD 422
IA V + FD LHT +AAQ M DDG G+ ++WRIE VPV+ YG FYGGD
Sbjct: 362 HIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGD 421
Query: 423 CYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEP 482
Y++LY Y G+ I+Y WQG ++QDE+AASA ++D + G VQ RV G EP
Sbjct: 422 SYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 481
Query: 483 RHFMAIFKGK-LVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND 541
H M++F GK ++I++GGTSR+G RLFQ+ N T+AVEV A +LNSND
Sbjct: 482 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 541
Query: 542 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTPY 601
F+L+T + YLW G G+S E+ A+EL +L VAEG EP FW+ LGGK Y
Sbjct: 542 AFVLKTPSAAYLWVGTGASEAEKTGAQELLRVL-RAQPVQVAEGSEPDGFWEALGGKAAY 600
Query: 602 ANDKRLQQEILDVQ-SRLFECSNKTGQFVVTEIT-DFTQDDLNPTDVMLLDTWDQVFLWI 659
RL+ + +D RLF CSNK G+FV+ E+ + Q+DL DVMLLDTWDQVF+W+
Sbjct: 601 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 660
Query: 660 GAEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWS 717
G ++ EK AL +A++Y+ T P+ RD TPI ++KQGFEPP F GWFL WD + WS
Sbjct: 661 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWS 718
>gi|189083772 gelsolin isoform b [Homo sapiens]
Length = 731
Score = 642 bits (1655), Expect = 0.0
Identities = 339/718 (47%), Positives = 442/718 (61%), Gaps = 14/718 (1%)
Query: 7 FRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVAS-LLSQDIHFWIGK 65
F +PG+ +WR+EK +L VP + +G+F+ GD YVIL T ++ + L D+H+W+G
Sbjct: 8 FLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGN 67
Query: 66 DSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKH 125
+ SQDE AAI+T QLDDYL G VQHREVQ ES TF GYFK G+ YK+GGVASG KH
Sbjct: 68 ECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKH 127
Query: 126 VETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERL 185
V N V+RL VKG+R +RATEV +SW+SFN GD F+LDLG I QW G SN ERL
Sbjct: 128 VVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERL 187
Query: 186 KAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEII-DQ 244
KA ++K IRD ER GRA + V E E PE M LG + + D D
Sbjct: 188 KATQVSKGIRDNERSGRARVHVSE---EGTEPEAML---QVLGPKPALPAGTEDTAKEDA 241
Query: 245 KQKSTIMLYHISDSAGQLAVTEVATR-PLVQDLLNHDDCYILDQSGT-KIYVWKGKGATK 302
+ LY +S+ AG ++V+ VA P Q L +DC+ILD KI+VWKGK A
Sbjct: 242 ANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANT 301
Query: 303 AEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFSIG 362
E++AA+ A FI YP T V + +G E+ +FKQ F+ W DQT GLG ++
Sbjct: 302 EERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSS 361
Query: 363 KIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGD 422
IA V + FD LHT +AAQ M DDG G+ ++WRIE VPV+ YG FYGGD
Sbjct: 362 HIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGD 421
Query: 423 CYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEP 482
Y++LY Y G+ I+Y WQG ++QDE+AASA ++D + G VQ RV G EP
Sbjct: 422 SYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 481
Query: 483 RHFMAIFKGK-LVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND 541
H M++F GK ++I++GGTSR+G RLFQ+ N T+AVEV A +LNSND
Sbjct: 482 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 541
Query: 542 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTPY 601
F+L+T + YLW G G+S E+ A+EL +L VAEG EP FW+ LGGK Y
Sbjct: 542 AFVLKTPSAAYLWVGTGASEAEKTGAQELLRVL-RAQPVQVAEGSEPDGFWEALGGKAAY 600
Query: 602 ANDKRLQQEILDVQ-SRLFECSNKTGQFVVTEIT-DFTQDDLNPTDVMLLDTWDQVFLWI 659
RL+ + +D RLF CSNK G+FV+ E+ + Q+DL DVMLLDTWDQVF+W+
Sbjct: 601 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 660
Query: 660 GAEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWS 717
G ++ EK AL +A++Y+ T P+ RD TPI ++KQGFEPP F GWFL WD + WS
Sbjct: 661 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWS 718
>gi|14916473 scinderin isoform 2 [Homo sapiens]
Length = 468
Score = 453 bits (1165), Expect = e-127
Identities = 229/470 (48%), Positives = 312/470 (66%), Gaps = 10/470 (2%)
Query: 252 LYHISDSAGQLAVTEVATR-PLVQDLLNHDDCYILDQSGTK-IYVWKGKGATKAEKQAAM 309
LY +SD++G + VT VA P +L ++C+ILD K I+VWKGK A E++AAM
Sbjct: 4 LYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAM 63
Query: 310 SKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFSIGKIAKVFQ 369
A F++ +Y +T ++ + +G E+ +FKQ F+ W KDQ+ G GK + K+A++ Q
Sbjct: 64 KTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKVAQIKQ 123
Query: 370 DKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGDCYLVLYT 429
FD + LH+ P++AAQ MVDDG+GKVE+WR+EN + V+ YG FYGGDCY++LYT
Sbjct: 124 IPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYT 183
Query: 430 YEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIF 489
Y I+Y WQG +A++DEL SA+ V++DR G AVQ+RV G EP H +++F
Sbjct: 184 YPRG----QIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLF 239
Query: 490 KGK-LVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLR-T 547
K K L+I++ GTS+KG P PP RLFQ+ N S T+ VEV A+SLNSNDVF+L+
Sbjct: 240 KDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLP 299
Query: 548 QAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTPYANDKRL 607
Q Y+W GKG+S +E A+ +AS+L + EG+EP EFW+ LGGK Y L
Sbjct: 300 QNSGYIWVGKGASQEEEKGAEYVASVL-KCKTLRIQEGEEPEEFWNSLGGKKDYQTSPLL 358
Query: 608 QQEILDVQSRLFECSNKTGQFVVTEIT-DFTQDDLNPTDVMLLDTWDQVFLWIGAEANAT 666
+ + D RL+ CSNKTG+FV+ EI +FTQDDL DVMLLD W+Q+F+WIG +AN
Sbjct: 359 ETQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEV 418
Query: 667 EKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIW 716
EK+ +L +A+ YL T PSGRD TPI+IIKQG EPP FTGWFL WD + W
Sbjct: 419 EKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 468
Score = 97.8 bits (242), Expect = 4e-20
Identities = 100/356 (28%), Positives = 151/356 (42%), Gaps = 55/356 (15%)
Query: 10 VDNDPGII-VWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGKDSS 68
VD+ G + +WR+E V +++G FY GDCY+IL T Q I+ W G +++
Sbjct: 144 VDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYP----RGQIIYTWQGANAT 199
Query: 69 QDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQG--IIYKQGGVASGMKHV 126
+DE + +A T QLD LGG VQ R Q E FK IIYK G G +
Sbjct: 200 RDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQAP 259
Query: 127 ETNTYDVKRLLHVKGKRNI----RATEVEMSWDSFNRGDVFLLDL---------GKVIIQ 173
T RL V +RN+ R EV++ +S N DVF+L L GK Q
Sbjct: 260 APPT----RLFQV--RRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQ 313
Query: 174 WNGPESNSGERLKAMLLAKDIRDRERGGRAEI-GVIEGDKEAASPELMKVLQDTLGRRSI 232
E E + ++L K +R +E E + G K+ + L++
Sbjct: 314 ---EEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQTSPLLET---------- 360
Query: 233 IKPTVPDEIIDQKQKSTIMLYHISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQSGTKI 292
Q + LY S+ G+ + E+ QD L DD +LD + +I
Sbjct: 361 -----------QAEDHPPRLYGCSNKTGRFVIEEIPGE-FTQDDLAEDDVMLLD-AWEQI 407
Query: 293 YVWKGKGATKAEKQAAMSKALGFIKM--KSYPSSTNVETVNDGAESAMFKQLFQKW 346
++W GK A + EK+ ++ A +++ T + + G E F F W
Sbjct: 408 FIWIGKDANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 463
>gi|4503743 flightless I homolog [Homo sapiens]
Length = 1269
Score = 280 bits (715), Expect = 5e-75
Identities = 232/783 (29%), Positives = 360/783 (45%), Gaps = 105/783 (13%)
Query: 14 PGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVAS-LLSQDIHFWIGKDSSQDEQ 72
PG+ +W+IE LV + HG FYE DCY++L T S L+ +I++WIG +++ D++
Sbjct: 499 PGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKK 558
Query: 73 SCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKHVETNTYD 132
+C+AI+ L +YLG RE ES+ F F I Y +GG ASG VE +T+
Sbjct: 559 ACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGFYTVE-DTHY 617
Query: 133 VKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLAK 192
V R+ V GK+NI+ V + S + VFLLD G I W G ++ KA L A+
Sbjct: 618 VTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAE 677
Query: 193 DIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEIIDQKQKSTIML 252
I ER G+AEI ++ +E PE + L G S IK VP++ + K L
Sbjct: 678 KINKNERKGKAEITLLVQGQEL--PEFWEALG---GEPSEIKKHVPEDFWPPQPK----L 728
Query: 253 YHISDSAGQLAVTEV--------ATRP---------LVQDLLNHDDCYILDQSGTKIYVW 295
Y + G L + ++ RP L+Q LL+ YILD + +++W
Sbjct: 729 YKVGLGLGYLELPQINYKLSVEHKQRPKVELMPRMRLLQSLLDTRCVYILD-CWSDVFIW 787
Query: 296 KGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWS---VKDQT 352
G+ + + + AA+ M P V +G E+ +FK F+ W D T
Sbjct: 788 LGRKSPRLVRAAALKLGQELCGMLHRPRHATVSRSLEGTEAQVFKAKFKNWDDVLTVDYT 847
Query: 353 MGLGKTF-SIGKIAKVFQD-------KFDVTLLHTKPE----VAAQERMVDDGN---GKV 397
S G KV +D K D+T L + +A E+++++ N +
Sbjct: 848 RNAEAVLQSPGLSGKVKRDAEKKDQMKADLTALFLPRQPPMSLAEAEQLMEEWNEDLDGM 907
Query: 398 EVWRIENLELVPVEYQWYGFFYGGDCYLVLYTY-----------------EVNGKPHH-- 438
E + +E + + + +G FY DCY+ L Y + GK
Sbjct: 908 EGFVLEGKKFARLPEEEFGHFYTQDCYVFLCRYWVPVEYEEEEKKEDKEEKAEGKEGEEA 967
Query: 439 ---------------ILYIWQGRHAS-QDELAASAYQAVEVDRQFDGAAVQVRVRMGTEP 482
I+Y WQGR AS L + + + F G VR+ E
Sbjct: 968 TAEAEEKQPEEDFQCIVYFWQGREASNMGWLTFTFSLQKKFESLFPGKLEVVRMTQQQEN 1027
Query: 483 RHFMAIFKGKLVIFEGGTSRKGNAEPDPPVRLFQIHGNDKS-NTKAVEVPAFASSLNSND 541
F++ FK K +I G RK P L+QI N + T+ +++ +S LNS
Sbjct: 1028 PKFLSHFKRKFIIHRG--KRKAVQGAQQP-SLYQIRTNGSALCTRCIQINTDSSLLNSEF 1084
Query: 542 VFLLRTQAEH-------YLWYGKGSSGDERAMAKELASLLCDG--SENTVAEGQEPAE-F 591
F+L+ E Y W G+ S DE +A+++ + + D S+ + EG+EP F
Sbjct: 1085 CFILKVPFESEDNQGIVYAWVGRASDPDEAKLAEDILNTMFDTSYSKQVINEGEEPENFF 1144
Query: 592 WDLLGGKTPYANDKRLQQEILDVQSRLFECSNKTGQFVVTE-ITDFTQDDLNPTDVMLLD 650
W +G + PY +D + +RLF CSN+ G F VTE +DF QDDL D+MLLD
Sbjct: 1145 WVGIGAQKPYDDDAEYMK-----HTRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLD 1199
Query: 651 TWDQVFLWIGAEANATEKESALATAQQYLHTHPSGRDPDTP--ILIIKQGFEPPIFTGWF 708
+V++W+G + + E + +L Q Y+ H ++ + P + ++++G E FT F
Sbjct: 1200 NGQEVYMWVGTQTSQVEIKLSLKACQVYIQ-HMRSKEHERPRRLRLVRKGNEQHAFTRCF 1258
Query: 709 LAW 711
AW
Sbjct: 1259 HAW 1261
Score = 120 bits (302), Expect = 4e-27
Identities = 96/345 (27%), Positives = 148/345 (42%), Gaps = 39/345 (11%)
Query: 399 VWRIENLELVPVEYQWYGFFYGGDCYLVLYTY-EVNGKPHHILYIWQGRHASQDELAASA 457
+W+IEN V VE ++G FY DCY+VL T+ + +G + +Y W G A+ D+ A SA
Sbjct: 503 IWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSA 562
Query: 458 YQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEGGTSRKGNAEPDP--PVRLF 515
AV + VR MG E F+ +F + EGGT+ D R++
Sbjct: 563 IHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGFYTVEDTHYVTRMY 622
Query: 516 QIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKELASLLC 575
+++G K N K VP +SL+ VFLL + Y+W G ++ A+ A +
Sbjct: 623 RVYG--KKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEKIN 680
Query: 576 DGSENTVAE------GQEPAEFWDLLGGKTPYANDKRLQQEILDVQSRLFECSNKTGQFV 629
AE GQE EFW+ LGG+ P K + ++ Q +L++ G
Sbjct: 681 KNERKGKAEITLLVQGQELPEFWEALGGE-PSEIKKHVPEDFWPPQPKLYKVGLGLGYLE 739
Query: 630 VTEIT-------------------DFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKES 670
+ +I Q L+ V +LD W VF+W+G ++ + +
Sbjct: 740 LPQINYKLSVEHKQRPKVELMPRMRLLQSLLDTRCVYILDCWSDVFIWLGRKSPRLVRAA 799
Query: 671 ALATAQQ---YLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWD 712
AL Q+ LH R + +G E +F F WD
Sbjct: 800 ALKLGQELCGMLH-----RPRHATVSRSLEGTEAQVFKAKFKNWD 839
Score = 42.4 bits (98), Expect = 0.002
Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 5/99 (5%)
Query: 252 LYHISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSK 311
L+ S+ G AVTE + QD L DD +LD +G ++Y+W G ++ E + ++
Sbjct: 1166 LFRCSNEKGYFAVTEKCS-DFCQDDLADDDIMLLD-NGQEVYMWVGTQTSQVEIKLSLKA 1223
Query: 312 ALGFI---KMKSYPSSTNVETVNDGAESAMFKQLFQKWS 347
+I + K + + V G E F + F WS
Sbjct: 1224 CQVYIQHMRSKEHERPRRLRLVRKGNEQHAFTRCFHAWS 1262
>gi|63252913 gelsolin-like capping protein [Homo sapiens]
Length = 348
Score = 257 bits (656), Expect = 3e-68
Identities = 149/349 (42%), Positives = 206/349 (59%), Gaps = 18/349 (5%)
Query: 5 SAFRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILST--RRVASLLSQDIHFW 62
S F DPG+ VWR+EK++ V G F+ GD Y++L V+ L H W
Sbjct: 10 SPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHL-----HLW 64
Query: 63 IGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASG 122
IG+ SS+DEQ A+ L+ LG PVQHREVQ +ESD F YF +G+ Y++GGV S
Sbjct: 65 IGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESA 124
Query: 123 MKHVETNT-YDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNS 181
T +K+L VKGK+NIRATE ++WDSFN GD F+LDLG+ I W G +SN
Sbjct: 125 FHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNI 184
Query: 182 GERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEI 241
ER KA LA IRD ER G+A++ ++ +E A E+++V LG + +K P+E
Sbjct: 185 LERNKARDLALAIRDSERQGKAQVEIVTDGEEPA--EMIQV----LGPKPALKEGNPEED 238
Query: 242 I--DQKQKSTIMLYHISDSAGQLAVTEVA-TRPLVQDLLNHDDCYILDQS-GTKIYVWKG 297
+ D+ LY +SD+ GQ+ +T+VA + P +LL DDC++LD KIY+WKG
Sbjct: 239 LTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKG 298
Query: 298 KGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKW 346
+ A + E+QAA+ A GFI Y +T VE + G ES +FKQ F+ W
Sbjct: 299 RKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDW 347
Score = 134 bits (336), Expect = 4e-31
Identities = 105/336 (31%), Positives = 163/336 (48%), Gaps = 30/336 (8%)
Query: 397 VEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKPHHI--LYIWQGRHASQDELA 454
+ VWR+E L+ VPV + G F+ GD YLVL+ NG P + L++W G+ +S+DE
Sbjct: 21 LHVWRVEKLKPVPVAQENQGVFFSGDSYLVLH----NG-PEEVSHLHLWIGQQSSRDEQG 75
Query: 455 ASAYQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEGGTS----RKGNAEPDP 510
A A AV ++ VQ R G E FM+ F L EGG + P
Sbjct: 76 ACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGAPAA 135
Query: 511 PVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKEL 570
+L+Q+ G K N +A E S N+ D F+L + W G S+ ER A++L
Sbjct: 136 IKKLYQVKG--KKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDL 193
Query: 571 ASLLCDGSE------NTVAEGQEPAEFWDLLGGKTPYAN---DKRLQQEILDVQ-SRLFE 620
A + D V +G+EPAE +LG K ++ L + + Q + L++
Sbjct: 194 ALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYK 253
Query: 621 CSNKTGQFVVTEITD---FTQDDLNPTDVMLLDT--WDQVFLWIGAEANATEKESALATA 675
S+ TGQ +T++ D F + L D +LD ++++W G +AN E+++AL A
Sbjct: 254 VSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVA 313
Query: 676 QQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAW 711
+ ++ P+T + I+ QG E PIF +F W
Sbjct: 314 EGFISRMQYA--PNTQVEILPQGHESPIFKQFFKDW 347
>gi|150417973 supervillin isoform 2 [Homo sapiens]
Length = 2214
Score = 182 bits (461), Expect = 1e-45
Identities = 208/801 (25%), Positives = 328/801 (40%), Gaps = 148/801 (18%)
Query: 136 LLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLAKDIR 195
LL +KG+R+++ VE + N GD FLL W G +N E+ KA LA I+
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 196 D-RERGGRAE-IGVIE---GDKEAASPELMKVLQDTLGRRSIIKPTVPDEIIDQKQKSTI 250
RE G RA I IE A+ + K+L +S P DE+ + T
Sbjct: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPK-EDELYEAAIIETN 1563
Query: 251 MLYHISDSAGQLAVTEVATRPLVQ-DLLNHDDCYILDQSGTKIYVWKGKGATKAEKQAAM 309
+Y + D +L + + + LL + + D G+++YVW GK T A+++ A
Sbjct: 1564 CIYRLMDD--KLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKIAF 1620
Query: 310 SKALGFIKMKSYPSSTNVETVNDGA-------------------------ESAMFKQLFQ 344
A + ++ ++ G E+ +FK+ F
Sbjct: 1621 QLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFL 1680
Query: 345 KWSVKDQTMGLGKTFSIGKIAKVFQDK------FDVTLLHTKPEVAAQERM--VDDGNG- 395
W+ ++ + G++A+ +D +DVT + + P+ A + V+ G G
Sbjct: 1681 DWTELKRS----NEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1736
Query: 396 ----------------KVEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVN------ 433
V+VW I + + Q G F+ GD Y+V + + V+
Sbjct: 1737 GLVEGHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSR 1796
Query: 434 ----------GKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEPR 483
GK + + WQGRH++ E SA VE+D + QV+V G EP
Sbjct: 1797 QKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEE---RGAQVQVLQGKEPP 1853
Query: 484 HFMAIFKGKLVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND-- 541
F+ F+G +V+ G + RL+ + G +EV SSL S
Sbjct: 1854 CFLQCFQGGMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSM 1912
Query: 542 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCD----------GSENTVAE---GQEP 588
V L +A YLW+G + + + + A+ + + S+ T+ E G EP
Sbjct: 1913 VVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEP 1972
Query: 589 AEFWDLLGGKTPYANDKRLQQE-ILDVQSRLFECSNKTGQFVVTEIT------------D 635
FWD LG + A D LQ + RLF S+ +G F TE
Sbjct: 1973 LGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMP 2032
Query: 636 FTQDDLNPTD---VMLLDTWDQVFLWIG---------AEAN---ATEKESALATAQQYLH 680
F Q+DL + L+D +V+LW G A A++++SA+ T QY
Sbjct: 2033 FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCK 2092
Query: 681 THPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWSAGKTYEQLKEELGDAAAIMRITA 740
+ + P +I G EP FT F +W E D A I +
Sbjct: 2093 GK-NLKKPAPKSYLIHAGLEPLTFTNMFPSW---------------EHREDIAEITEMDT 2136
Query: 741 DMKNATLSLNSNDSE--PKYYPIAVLLKNQNQELPEDVNPAKKENYLSEQDFVSVFGITR 798
++ N + ++ YP+A LL + LPE V+P K E YL+++DF +TR
Sbjct: 2137 EVSNQITLVEDVLAKLCKTIYPLADLLA---RPLPEGVDPLKLEIYLTDEDFEFALDMTR 2193
Query: 799 GQFAALPGWKQLQMKKEKGLF 819
++ ALP WKQ+ +KK KGLF
Sbjct: 2194 DEYNALPAWKQVNLKKAKGLF 2214
Score = 61.2 bits (147), Expect = 4e-09
Identities = 55/192 (28%), Positives = 87/192 (45%), Gaps = 23/192 (11%)
Query: 505 NAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDER 564
+A P + L QI G T+ VE A S+LNS D FLL + +LW G+ ++ E+
Sbjct: 1436 SAVPYKRLMLLQIKGRRHVQTRLVEPRA--SALNSGDCFLLLSPHCCFLWVGEFANVIEK 1493
Query: 565 AMAKELASLLCDGSE--------NTVAEG-----QEPAEFWDLLGGKTPY--ANDKRLQQ 609
A A ELA+L+ E T+ EG +FW LLGG+T Y A D + +
Sbjct: 1494 AKASELATLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPK-ED 1552
Query: 610 EILDVQSRLFECSNKTGQFVVTEITDF-----TQDDLNPTDVMLLDTWDQVFLWIGAEAN 664
E+ + C + + D+ L P +V++ D +V++W G E
Sbjct: 1553 ELYEAAIIETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVT 1612
Query: 665 ATEKESALATAQ 676
+++ A A+
Sbjct: 1613 LAQRKIAFQLAK 1624
Score = 58.9 bits (141), Expect = 2e-08
Identities = 84/383 (21%), Positives = 157/383 (40%), Gaps = 62/383 (16%)
Query: 18 VWRIEKMELALVPVSAHGNFYEGDCYVI-----LSTR-----------RVASLLSQDIHF 61
VW I + + + +P + G F+EGD YV+ +ST R A F
Sbjct: 1756 VWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVYFF 1815
Query: 62 WIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVAS 121
W G+ S+ E+ +A+ T +LD+ G Q + +Q E F F+ G++ G
Sbjct: 1816 WQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEPPCFLQCFQGGMVVHSG---- 1868
Query: 122 GMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSF---NRGDVFLLDLGKVIIQ-WNGP 177
+ E N RL V+G+ + +E++ +R + +L++ K +I W+G
Sbjct: 1869 RREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHGC 1928
Query: 178 ESNSGERLKAMLLAKDIRDR---ERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIK 234
++ + + A I+++ E G + V + + S L D LGRR
Sbjct: 1929 KAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPL--GFWDALGRRD--- 1983
Query: 235 PTVPDEIIDQKQKSTI--MLYHISDSAGQLAVTE----------VATRPLVQDLLNH--D 280
D ++ L+ +S S+G A TE V++ P +Q+ L
Sbjct: 1984 RKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAPQ 2043
Query: 281 DCYILDQSGTKIYVWKG--------KGATK----AEKQAAMSKALGFIKMKSYPS-STNV 327
L + ++Y+W+G G+ + +++++AM L + K K+ +
Sbjct: 2044 PALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPAPKS 2103
Query: 328 ETVNDGAESAMFKQLFQKWSVKD 350
++ G E F +F W ++
Sbjct: 2104 YLIHAGLEPLTFTNMFPSWEHRE 2126
>gi|150417971 supervillin isoform 1 [Homo sapiens]
Length = 1788
Score = 182 bits (461), Expect = 1e-45
Identities = 208/801 (25%), Positives = 328/801 (40%), Gaps = 148/801 (18%)
Query: 136 LLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLAKDIR 195
LL +KG+R+++ VE + N GD FLL W G +N E+ KA LA I+
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 196 D-RERGGRAE-IGVIE---GDKEAASPELMKVLQDTLGRRSIIKPTVPDEIIDQKQKSTI 250
RE G RA I IE A+ + K+L +S P DE+ + T
Sbjct: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPK-EDELYEAAIIETN 1137
Query: 251 MLYHISDSAGQLAVTEVATRPLVQ-DLLNHDDCYILDQSGTKIYVWKGKGATKAEKQAAM 309
+Y + D +L + + + LL + + D G+++YVW GK T A+++ A
Sbjct: 1138 CIYRLMDD--KLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKIAF 1194
Query: 310 SKALGFIKMKSYPSSTNVETVNDGA-------------------------ESAMFKQLFQ 344
A + ++ ++ G E+ +FK+ F
Sbjct: 1195 QLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFL 1254
Query: 345 KWSVKDQTMGLGKTFSIGKIAKVFQDK------FDVTLLHTKPEVAAQERM--VDDGNG- 395
W+ ++ + G++A+ +D +DVT + + P+ A + V+ G G
Sbjct: 1255 DWTELKRS----NEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1310
Query: 396 ----------------KVEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVN------ 433
V+VW I + + Q G F+ GD Y+V + + V+
Sbjct: 1311 GLVEGHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSR 1370
Query: 434 ----------GKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEPR 483
GK + + WQGRH++ E SA VE+D + QV+V G EP
Sbjct: 1371 QKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEE---RGAQVQVLQGKEPP 1427
Query: 484 HFMAIFKGKLVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND-- 541
F+ F+G +V+ G + RL+ + G +EV SSL S
Sbjct: 1428 CFLQCFQGGMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSM 1486
Query: 542 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCD----------GSENTVAE---GQEP 588
V L +A YLW+G + + + + A+ + + S+ T+ E G EP
Sbjct: 1487 VVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEP 1546
Query: 589 AEFWDLLGGKTPYANDKRLQQE-ILDVQSRLFECSNKTGQFVVTEIT------------D 635
FWD LG + A D LQ + RLF S+ +G F TE
Sbjct: 1547 LGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMP 1606
Query: 636 FTQDDLNPTD---VMLLDTWDQVFLWIG---------AEAN---ATEKESALATAQQYLH 680
F Q+DL + L+D +V+LW G A A++++SA+ T QY
Sbjct: 1607 FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCK 1666
Query: 681 THPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWSAGKTYEQLKEELGDAAAIMRITA 740
+ + P +I G EP FT F +W E D A I +
Sbjct: 1667 GK-NLKKPAPKSYLIHAGLEPLTFTNMFPSW---------------EHREDIAEITEMDT 1710
Query: 741 DMKNATLSLNSNDSE--PKYYPIAVLLKNQNQELPEDVNPAKKENYLSEQDFVSVFGITR 798
++ N + ++ YP+A LL + LPE V+P K E YL+++DF +TR
Sbjct: 1711 EVSNQITLVEDVLAKLCKTIYPLADLLA---RPLPEGVDPLKLEIYLTDEDFEFALDMTR 1767
Query: 799 GQFAALPGWKQLQMKKEKGLF 819
++ ALP WKQ+ +KK KGLF
Sbjct: 1768 DEYNALPAWKQVNLKKAKGLF 1788
Score = 61.2 bits (147), Expect = 4e-09
Identities = 55/192 (28%), Positives = 87/192 (45%), Gaps = 23/192 (11%)
Query: 505 NAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDER 564
+A P + L QI G T+ VE A S+LNS D FLL + +LW G+ ++ E+
Sbjct: 1010 SAVPYKRLMLLQIKGRRHVQTRLVEPRA--SALNSGDCFLLLSPHCCFLWVGEFANVIEK 1067
Query: 565 AMAKELASLLCDGSE--------NTVAEG-----QEPAEFWDLLGGKTPY--ANDKRLQQ 609
A A ELA+L+ E T+ EG +FW LLGG+T Y A D + +
Sbjct: 1068 AKASELATLIQTKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPK-ED 1126
Query: 610 EILDVQSRLFECSNKTGQFVVTEITDF-----TQDDLNPTDVMLLDTWDQVFLWIGAEAN 664
E+ + C + + D+ L P +V++ D +V++W G E
Sbjct: 1127 ELYEAAIIETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGKEVT 1186
Query: 665 ATEKESALATAQ 676
+++ A A+
Sbjct: 1187 LAQRKIAFQLAK 1198
Score = 58.9 bits (141), Expect = 2e-08
Identities = 84/383 (21%), Positives = 157/383 (40%), Gaps = 62/383 (16%)
Query: 18 VWRIEKMELALVPVSAHGNFYEGDCYVI-----LSTR-----------RVASLLSQDIHF 61
VW I + + + +P + G F+EGD YV+ +ST R A F
Sbjct: 1330 VWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVYFF 1389
Query: 62 WIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVAS 121
W G+ S+ E+ +A+ T +LD+ G Q + +Q E F F+ G++ G
Sbjct: 1390 WQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEPPCFLQCFQGGMVVHSG---- 1442
Query: 122 GMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSF---NRGDVFLLDLGKVIIQ-WNGP 177
+ E N RL V+G+ + +E++ +R + +L++ K +I W+G
Sbjct: 1443 RREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHGC 1502
Query: 178 ESNSGERLKAMLLAKDIRDR---ERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIK 234
++ + + A I+++ E G + V + + S L D LGRR
Sbjct: 1503 KAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPL--GFWDALGRRD--- 1557
Query: 235 PTVPDEIIDQKQKSTI--MLYHISDSAGQLAVTE----------VATRPLVQDLLNH--D 280
D ++ L+ +S S+G A TE V++ P +Q+ L
Sbjct: 1558 RKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAPQ 1617
Query: 281 DCYILDQSGTKIYVWKG--------KGATK----AEKQAAMSKALGFIKMKSYPS-STNV 327
L + ++Y+W+G G+ + +++++AM L + K K+ +
Sbjct: 1618 PALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPAPKS 1677
Query: 328 ETVNDGAESAMFKQLFQKWSVKD 350
++ G E F +F W ++
Sbjct: 1678 YLIHAGLEPLTFTNMFPSWEHRE 1700
>gi|7662330 actin binding LIM protein family, member 3 [Homo
sapiens]
Length = 683
Score = 50.4 bits (119), Expect = 6e-06
Identities = 27/74 (36%), Positives = 43/74 (58%), Gaps = 2/74 (2%)
Query: 748 SLNSNDSEPKYYPIAVLLKNQN--QELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALP 805
++N E K YP +LL LP+DV+ + E +LS+++F VFG+T +F L
Sbjct: 610 AVNWGMREYKIYPYELLLVTTRGRNRLPKDVDRTRLERHLSQEEFYQVFGMTISEFDRLA 669
Query: 806 GWKQLQMKKEKGLF 819
WK+ ++KK+ LF
Sbjct: 670 LWKRNELKKQARLF 683
>gi|166706877 erythrocyte membrane protein band 4.9 isoform 1 [Homo
sapiens]
Length = 405
Score = 42.7 bits (99), Expect = 0.001
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 755 EPKYYPIAVLLKNQN--QELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALPGWKQLQM 812
E K YP +L+ +LP V+ + E +LS +DF VF ++ +F L WK+ ++
Sbjct: 339 EQKIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNEL 398
Query: 813 KKEKGLF 819
KK+ LF
Sbjct: 399 KKKASLF 405
>gi|166706879 erythrocyte membrane protein band 4.9 isoform 1 [Homo
sapiens]
Length = 405
Score = 42.7 bits (99), Expect = 0.001
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 755 EPKYYPIAVLLKNQN--QELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALPGWKQLQM 812
E K YP +L+ +LP V+ + E +LS +DF VF ++ +F L WK+ ++
Sbjct: 339 EQKIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNEL 398
Query: 813 KKEKGLF 819
KK+ LF
Sbjct: 399 KKKASLF 405
>gi|166706875 erythrocyte membrane protein band 4.9 isoform 1 [Homo
sapiens]
Length = 405
Score = 42.7 bits (99), Expect = 0.001
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 755 EPKYYPIAVLLKNQN--QELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALPGWKQLQM 812
E K YP +L+ +LP V+ + E +LS +DF VF ++ +F L WK+ ++
Sbjct: 339 EQKIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNEL 398
Query: 813 KKEKGLF 819
KK+ LF
Sbjct: 399 KKKASLF 405
>gi|153792514 actin binding LIM protein family, member 2 isoform 6
[Homo sapiens]
Length = 521
Score = 42.7 bits (99), Expect = 0.001
Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 750 NSNDSEPKYYPIAVLLKNQN--QELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALPGW 807
+S S+ K YP L+ +LP+DV+ + E +LS ++F VFG++ +F L W
Sbjct: 450 DSFHSQYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALW 509
Query: 808 KQLQMKKEKGLF 819
K+ +KK+ LF
Sbjct: 510 KRNDLKKKALLF 521
>gi|194272204 actin binding LIM protein family, member 2 isoform 5
[Homo sapiens]
Length = 531
Score = 42.7 bits (99), Expect = 0.001
Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 750 NSNDSEPKYYPIAVLLKNQN--QELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALPGW 807
+S S+ K YP L+ +LP+DV+ + E +LS ++F VFG++ +F L W
Sbjct: 460 DSFHSQYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALW 519
Query: 808 KQLQMKKEKGLF 819
K+ +KK+ LF
Sbjct: 520 KRNDLKKKALLF 531
>gi|194272202 actin binding LIM protein family, member 2 isoform 4
[Homo sapiens]
Length = 559
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 9/88 (10%)
Query: 741 DMKNATLSLNSNDS-------EPKYYPIAVLLKNQN--QELPEDVNPAKKENYLSEQDFV 791
D +NA L+ D E K YP L+ +LP+DV+ + E +LS ++F
Sbjct: 472 DQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQ 531
Query: 792 SVFGITRGQFAALPGWKQLQMKKEKGLF 819
VFG++ +F L WK+ +KK+ LF
Sbjct: 532 EVFGMSIEEFDRLALWKRNDLKKKALLF 559
>gi|194272200 actin binding LIM protein family, member 2 isoform 3
[Homo sapiens]
Length = 572
Score = 42.7 bits (99), Expect = 0.001
Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 750 NSNDSEPKYYPIAVLLKNQN--QELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALPGW 807
+S S+ K YP L+ +LP+DV+ + E +LS ++F VFG++ +F L W
Sbjct: 501 DSFHSQYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALW 560
Query: 808 KQLQMKKEKGLF 819
K+ +KK+ LF
Sbjct: 561 KRNDLKKKALLF 572
>gi|194272198 actin binding LIM protein family, member 2 isoform 2
[Homo sapiens]
Length = 611
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 9/88 (10%)
Query: 741 DMKNATLSLNSNDS-------EPKYYPIAVLLKNQN--QELPEDVNPAKKENYLSEQDFV 791
D +NA L+ D E K YP L+ +LP+DV+ + E +LS ++F
Sbjct: 524 DQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQ 583
Query: 792 SVFGITRGQFAALPGWKQLQMKKEKGLF 819
VFG++ +F L WK+ +KK+ LF
Sbjct: 584 EVFGMSIEEFDRLALWKRNDLKKKALLF 611
>gi|194272196 actin binding LIM protein family, member 2 isoform 1
[Homo sapiens]
Length = 645
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 9/88 (10%)
Query: 741 DMKNATLSLNSNDS-------EPKYYPIAVLLKNQN--QELPEDVNPAKKENYLSEQDFV 791
D +NA L+ D E K YP L+ +LP+DV+ + E +LS ++F
Sbjct: 558 DQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQ 617
Query: 792 SVFGITRGQFAALPGWKQLQMKKEKGLF 819
VFG++ +F L WK+ +KK+ LF
Sbjct: 618 EVFGMSIEEFDRLALWKRNDLKKKALLF 645
>gi|166706885 erythrocyte membrane protein band 4.9 isoform 3 [Homo
sapiens]
Length = 358
Score = 41.6 bits (96), Expect = 0.003
Identities = 20/61 (32%), Positives = 34/61 (55%)
Query: 759 YPIAVLLKNQNQELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALPGWKQLQMKKEKGL 818
Y + V+ +LP V+ + E +LS +DF VF ++ +F L WK+ ++KK+ L
Sbjct: 298 YEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASL 357
Query: 819 F 819
F
Sbjct: 358 F 358
>gi|166706883 erythrocyte membrane protein band 4.9 isoform 2 [Homo
sapiens]
Length = 383
Score = 41.6 bits (96), Expect = 0.003
Identities = 20/61 (32%), Positives = 34/61 (55%)
Query: 759 YPIAVLLKNQNQELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALPGWKQLQMKKEKGL 818
Y + V+ +LP V+ + E +LS +DF VF ++ +F L WK+ ++KK+ L
Sbjct: 323 YEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASL 382
Query: 819 F 819
F
Sbjct: 383 F 383
>gi|166706881 erythrocyte membrane protein band 4.9 isoform 2 [Homo
sapiens]
Length = 383
Score = 41.6 bits (96), Expect = 0.003
Identities = 20/61 (32%), Positives = 34/61 (55%)
Query: 759 YPIAVLLKNQNQELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALPGWKQLQMKKEKGL 818
Y + V+ +LP V+ + E +LS +DF VF ++ +F L WK+ ++KK+ L
Sbjct: 323 YEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASL 382
Query: 819 F 819
F
Sbjct: 383 F 383
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,714,062
Number of Sequences: 37866
Number of extensions: 1352774
Number of successful extensions: 3167
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2778
Number of HSP's gapped (non-prelim): 89
length of query: 819
length of database: 18,247,518
effective HSP length: 111
effective length of query: 708
effective length of database: 14,044,392
effective search space: 9943429536
effective search space used: 9943429536
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.