Search of human proteins with 17505907

Search of human proteins with 17505907

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1
[Homo sapiens]
         (851 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1 ...  1694   0.0  
gi|20336298 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 2 ...  1159   0.0  
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi...   280   3e-75
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi...   242   9e-64
gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo sapi...   216   7e-56
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi...   191   2e-48
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   189   7e-48
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   180   4e-45
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]    175   1e-43
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         174   4e-43
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          174   4e-43
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  168   2e-41
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   166   8e-41
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]            166   1e-40
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]            166   1e-40
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...   164   2e-40
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   162   9e-40
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   162   9e-40
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   159   1e-38
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi...   155   1e-37
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...   155   2e-37
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...   155   2e-37
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   154   3e-37
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ...   150   4e-36
gi|13129006 nucleolar protein GU2 [Homo sapiens]                      149   8e-36
gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens]   140   5e-33
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...   138   2e-32
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ...   132   1e-30
gi|8922976 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 [Homo sapiens]   129   9e-30
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...   129   1e-29

>gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1
           [Homo sapiens]
          Length = 851

 Score = 1694 bits (4386), Expect = 0.0
 Identities = 851/851 (100%), Positives = 851/851 (100%)

Query: 1   MAPDLASQRHSESFPSVNSRPNVILPGREGRREGLPPGGGTRGSLVPTRPVPPSPAPLGT 60
           MAPDLASQRHSESFPSVNSRPNVILPGREGRREGLPPGGGTRGSLVPTRPVPPSPAPLGT
Sbjct: 1   MAPDLASQRHSESFPSVNSRPNVILPGREGRREGLPPGGGTRGSLVPTRPVPPSPAPLGT 60

Query: 61  SPYSWSRSGPGRGGGAGSSRVPRGVPGPAVCAPGSLLHHASPTQTMAAADGSLFDNPRTF 120
           SPYSWSRSGPGRGGGAGSSRVPRGVPGPAVCAPGSLLHHASPTQTMAAADGSLFDNPRTF
Sbjct: 61  SPYSWSRSGPGRGGGAGSSRVPRGVPGPAVCAPGSLLHHASPTQTMAAADGSLFDNPRTF 120

Query: 121 SRRPPAQASRQAKATKRKYQASSEAPPAKRRNETSFLPAKKTSVKETQRTFKGNAQKMFS 180
           SRRPPAQASRQAKATKRKYQASSEAPPAKRRNETSFLPAKKTSVKETQRTFKGNAQKMFS
Sbjct: 121 SRRPPAQASRQAKATKRKYQASSEAPPAKRRNETSFLPAKKTSVKETQRTFKGNAQKMFS 180

Query: 181 PKKHSVSTSDRNQEERQCIKTSSLFKNNPDIPELHRPVVKQVQEKVFTSAAFHELGLHPH 240
           PKKHSVSTSDRNQEERQCIKTSSLFKNNPDIPELHRPVVKQVQEKVFTSAAFHELGLHPH
Sbjct: 181 PKKHSVSTSDRNQEERQCIKTSSLFKNNPDIPELHRPVVKQVQEKVFTSAAFHELGLHPH 240

Query: 241 LISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKI 300
           LISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKI
Sbjct: 241 LISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKI 300

Query: 301 QRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINIL 360
           QRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINIL
Sbjct: 301 QRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINIL 360

Query: 361 ISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVL 420
           ISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVL
Sbjct: 361 ISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVL 420

Query: 421 LSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPES 480
           LSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPES
Sbjct: 421 LSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPES 480

Query: 481 LKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGA 540
           LKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGA
Sbjct: 481 LKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGA 540

Query: 541 PASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWI 600
           PASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWI
Sbjct: 541 PASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWI 600

Query: 601 VQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDILC 660
           VQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDILC
Sbjct: 601 VQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDILC 660

Query: 661 VLTRDDCFKGKRWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKALQSFIQ 720
           VLTRDDCFKGKRWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKALQSFIQ
Sbjct: 661 VLTRDDCFKGKRWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKALQSFIQ 720

Query: 721 AYATYPRELKHIFHVRSLHLGHVAKSFGLRDAPRNLSALTRKKRKAHVKRPDLHKKTQSK 780
           AYATYPRELKHIFHVRSLHLGHVAKSFGLRDAPRNLSALTRKKRKAHVKRPDLHKKTQSK
Sbjct: 721 AYATYPRELKHIFHVRSLHLGHVAKSFGLRDAPRNLSALTRKKRKAHVKRPDLHKKTQSK 780

Query: 781 HSLAEILRSEYSSGMEADIAKVKKQNAPGEPGGRPLQHSLQPTPCFGRGKTLKWRKTQKG 840
           HSLAEILRSEYSSGMEADIAKVKKQNAPGEPGGRPLQHSLQPTPCFGRGKTLKWRKTQKG
Sbjct: 781 HSLAEILRSEYSSGMEADIAKVKKQNAPGEPGGRPLQHSLQPTPCFGRGKTLKWRKTQKG 840

Query: 841 VQRDSKTSQKV 851
           VQRDSKTSQKV
Sbjct: 841 VQRDSKTSQKV 851


>gi|20336298 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 2
           [Homo sapiens]
          Length = 585

 Score = 1159 bits (2999), Expect = 0.0
 Identities = 585/585 (100%), Positives = 585/585 (100%)

Query: 1   MAPDLASQRHSESFPSVNSRPNVILPGREGRREGLPPGGGTRGSLVPTRPVPPSPAPLGT 60
           MAPDLASQRHSESFPSVNSRPNVILPGREGRREGLPPGGGTRGSLVPTRPVPPSPAPLGT
Sbjct: 1   MAPDLASQRHSESFPSVNSRPNVILPGREGRREGLPPGGGTRGSLVPTRPVPPSPAPLGT 60

Query: 61  SPYSWSRSGPGRGGGAGSSRVPRGVPGPAVCAPGSLLHHASPTQTMAAADGSLFDNPRTF 120
           SPYSWSRSGPGRGGGAGSSRVPRGVPGPAVCAPGSLLHHASPTQTMAAADGSLFDNPRTF
Sbjct: 61  SPYSWSRSGPGRGGGAGSSRVPRGVPGPAVCAPGSLLHHASPTQTMAAADGSLFDNPRTF 120

Query: 121 SRRPPAQASRQAKATKRKYQASSEAPPAKRRNETSFLPAKKTSVKETQRTFKGNAQKMFS 180
           SRRPPAQASRQAKATKRKYQASSEAPPAKRRNETSFLPAKKTSVKETQRTFKGNAQKMFS
Sbjct: 121 SRRPPAQASRQAKATKRKYQASSEAPPAKRRNETSFLPAKKTSVKETQRTFKGNAQKMFS 180

Query: 181 PKKHSVSTSDRNQEERQCIKTSSLFKNNPDIPELHRPVVKQVQEKVFTSAAFHELGLHPH 240
           PKKHSVSTSDRNQEERQCIKTSSLFKNNPDIPELHRPVVKQVQEKVFTSAAFHELGLHPH
Sbjct: 181 PKKHSVSTSDRNQEERQCIKTSSLFKNNPDIPELHRPVVKQVQEKVFTSAAFHELGLHPH 240

Query: 241 LISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKI 300
           LISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKI
Sbjct: 241 LISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKI 300

Query: 301 QRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINIL 360
           QRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINIL
Sbjct: 301 QRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINIL 360

Query: 361 ISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVL 420
           ISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVL
Sbjct: 361 ISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVL 420

Query: 421 LSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPES 480
           LSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPES
Sbjct: 421 LSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPES 480

Query: 481 LKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGA 540
           LKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGA
Sbjct: 481 LKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGA 540

Query: 541 PASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCT 585
           PASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCT
Sbjct: 541 PASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCT 585


>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
           sapiens]
          Length = 670

 Score =  280 bits (717), Expect = 3e-75
 Identities = 207/620 (33%), Positives = 324/620 (52%), Gaps = 100/620 (16%)

Query: 147 PAKRRNETSFLPAKKTSVKETQRTFKGNAQKMFS---PKKHSVSTSDRNQEERQCIKTSS 203
           P K    T+   A ++S  E+++  K   +KM +   P      T ++ + E +  +T+ 
Sbjct: 87  PQKSTVLTNGEAAMQSSNSESKKK-KKKKRKMVNDAEPDTKKAKTENKGKSEEESAETTK 145

Query: 204 LFKNNPDIPELHRPVVKQVQEKVFTSAAFHELGLHP--HLIS--TINTVLKM--SSMTSV 257
             +NN + P+      +     +  + AF +       +L++  T+  + +M  ++MT +
Sbjct: 146 ETENNVEKPDNDEDESEVPSLPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNMTEI 205

Query: 258 QKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPTREL 317
           Q +SI  LLEGRD L  ++TGSGKTLA+ IP V+ +  ++ +    +G   L+L PTREL
Sbjct: 206 QHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELI--VKLRFMPRNGTGVLILSPTREL 263

Query: 318 ALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNI 377
           A+Q+F  +++L+        G++MGG  R +E  +L  GINI+++TPGRL+DH+++T   
Sbjct: 264 AMQTFGVLKELMTHHVHTY-GLIMGGSNRSAEAQKLGNGINIIVATPGRLLDHMQNTPGF 322

Query: 378 HFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADISL 437
            +  L+ LV DEADRILD+GFE+++  I+  +     +RQ +L SAT T  V  LA ISL
Sbjct: 323 MYKNLQCLVIDEADRILDVGFEEELKQIIKLLPT---RRQTMLFSATQTRKVEDLARISL 379

Query: 438 H-DPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVC 496
             +P+ + V D         DKA   V               + L+Q   V PS+ R + 
Sbjct: 380 KKEPLYVGVDD---------DKANATV---------------DGLEQGYVVCPSEKRFLL 415

Query: 497 LAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSASMRLKFL 556
           L  F+ +  K    +K++VFFSSC  V++HY L                     + L  L
Sbjct: 416 LFTFLKKNRK----KKLMVFFSSCMSVKYHYELLNY------------------IDLPVL 453

Query: 557 RLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRI 616
            +HG  +Q +RT  F +F ++  G LLCTDVAARGLD+P+V WIVQY+ P  P EYIHR+
Sbjct: 454 AIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRV 513

Query: 617 GRTAR-IGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDILCVLTRDDCFKGKRWGA 675
           GRTAR +   G +LLIL P E  ++  L   K+ +SE                    W  
Sbjct: 514 GRTARGLNGRGHALLILRPEELGFLRYLKQSKVPLSEFDFS----------------W-- 555

Query: 676 QKSHAVGPQEIRERATVLQTVFED--YVHSSERRVSWAKKALQSFIQAYATYPRELKHIF 733
                    +I +  + L+ + E   ++H S      A++A +S+I+AY ++   LK IF
Sbjct: 556 --------SKISDIQSQLEKLIEKNYFLHKS------AQEAYKSYIRAYDSH--SLKQIF 599

Query: 734 HVRSLHLGHVAKSFGLRDAP 753
           +V +L+L  VA SFG +  P
Sbjct: 600 NVNNLNLPQVALSFGFKVPP 619


>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
           sapiens]
          Length = 875

 Score =  242 bits (618), Expect = 9e-64
 Identities = 172/503 (34%), Positives = 258/503 (51%), Gaps = 87/503 (17%)

Query: 254 MTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVP 313
           +T +QKQ+I + L+G+D L  ++TGSGKTLA+ +PV+++L  ++     +DG   L++ P
Sbjct: 92  VTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWT--STDGLGVLIISP 149

Query: 314 TRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKS 373
           TRELA Q+F+ ++K+ K   +   G+++GG+  K E  R+   INIL+ TPGRL+ H+  
Sbjct: 150 TRELAYQTFEVLRKVGKNHDFSA-GLIIGGKDLKHEAERINN-INILVCTPGRLLQHMDE 207

Query: 374 TKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLA 433
           T + H + L+ LV DEADRILD+GF   +  ++  +    +KRQ +L SAT T+ V  LA
Sbjct: 208 TVSFHATDLQMLVLDEADRILDMGFADTMNAVIENLP---KKRQTLLFSATQTKSVKDLA 264

Query: 434 DISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLR 493
            +SL +P  + V +K+                         ++ P +L+Q+  V   + +
Sbjct: 265 RLSLKNPEYVWVHEKA------------------------KYSTPATLEQNYIVCELQQK 300

Query: 494 LVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSASMRL 553
           +  L +F+    K    +K +VFFSSC+ V++ Y +F +              P  S+  
Sbjct: 301 ISVLYSFLRSHLK----KKSIVFFSSCKEVQYLYRVFCRLR------------PGVSI-- 342

Query: 554 KFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYI 613
             L LHG  +Q  R  V+ EF   R  VL  TD+AARGLD P V W++Q++ P     YI
Sbjct: 343 --LALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYI 400

Query: 614 HRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKM--EDILCVLTRDDCFKGK 671
           HR GRTAR    G +LLIL PSE   V  L   K+ V EIK+  E ++ V  +       
Sbjct: 401 HRAGRTARYKEDGEALLILLPSEKAMVQQLLQKKVPVKEIKINPEKLIDVQKK------- 453

Query: 672 RWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKALQSFIQAYATYPRELKH 731
                +S     Q+++ERA   Q  F  YV S                     Y  + K 
Sbjct: 454 ----LESILAQDQDLKERA---QRCFVSYVRS--------------------VYLMKDKE 486

Query: 732 IFHVRSLHLGHVAKSFGLRDAPR 754
           +F V  L +   A S GL  APR
Sbjct: 487 VFDVSKLPIPEYALSLGLAVAPR 509


>gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo
           sapiens]
          Length = 600

 Score =  216 bits (550), Expect = 7e-56
 Identities = 163/525 (31%), Positives = 258/525 (49%), Gaps = 85/525 (16%)

Query: 237 LHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAM 296
           LHP ++  +   L    MT VQ  +IP+ +  +D    + TGSGKTLA+ IP+++ L   
Sbjct: 16  LHPQVLGALRE-LGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPILEILLRR 74

Query: 297 ESKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRK- 355
           E K+++S    A+++ PTRELA+Q  + +    K F      + +GG     +  R ++ 
Sbjct: 75  EEKLKKSQVG-AIIITPTRELAIQIDEVLSHFTKHFPEFSQILWIGGRNPGEDVERFKQQ 133

Query: 356 GINILISTPGRLVDHIK-STKNIHFSR----LRWLVFDEADRILDLGFEKDITVILNAVN 410
           G NI+++TPGRL D  +   + +  +     L  LV DEADR+LD+GFE  I  IL  + 
Sbjct: 134 GGNIIVATPGRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINTILEFLP 193

Query: 411 AECQKRQNVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGD 470
              ++R+  L SAT T+ V  L    L +PV +SV          K+K V          
Sbjct: 194 ---KQRRTGLFSATQTQEVENLVRAGLRNPVRVSV----------KEKGVAASSAQKT-- 238

Query: 471 KLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLF 530
                  P  L+ +  V  +  +   L  F+    +  + +K +VFFS+C  VE+ Y   
Sbjct: 239 -------PSRLENYYMVCKADEKFNQLVHFL----RNHKQEKHLVFFSTCACVEY-YGKA 286

Query: 531 LQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAAR 590
           L+ L+                 +K + +HG M+ + R  +F EF   + G+L+CTDV AR
Sbjct: 287 LEVLVKG---------------VKIMCIHGKMKYK-RNKIFMEFRKLQSGILVCTDVMAR 330

Query: 591 GLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLA-SHKIN 649
           G+D+P+V W++QY+ PS+ + ++HR GRTARIG  GS+L+ L P E  Y+N LA + K  
Sbjct: 331 GIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVFLLPMEESYINFLAINQKCP 390

Query: 650 VSEIKMEDILCVLTRDDCFKGKRWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVS 709
           + E+K                     Q++ A    +++  A   + VFE           
Sbjct: 391 LQEMK--------------------PQRNTADLLPKLKSMALADRAVFEK---------- 420

Query: 710 WAKKALQSFIQAYATYPRELKHIFHVRSLHLGHVAKSFGLRDAPR 754
              KA  S++QAYA +  E   IF ++ L    +A+ F L   P+
Sbjct: 421 -GMKAFVSYVQAYAKH--ECNLIFRLKDLDFASLARGFALLRMPK 462


>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
           sapiens]
          Length = 483

 Score =  191 bits (485), Expect = 2e-48
 Identities = 138/441 (31%), Positives = 218/441 (49%), Gaps = 61/441 (13%)

Query: 230 AAFHELGLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPV 289
           A F ELGL   L+      L +   T VQ   IP +LEGRD L  ++TGSGKT A+ +P+
Sbjct: 2   AGFAELGLSSWLVEQCRQ-LGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPI 60

Query: 290 VQSLQAMESKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSE 349
           +Q L       +   G + LVL PTRELA Q  +  + L KP   +   +++GG    ++
Sbjct: 61  LQKLS------EDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLG-LKDCIIVGGMDMVAQ 113

Query: 350 KARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLG---FEKDITVIL 406
              L +  +++I+TPGRL DH++S+      ++R+LV DEADR+L+ G   F  D+  IL
Sbjct: 114 ALELSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAIL 173

Query: 407 NAVNAECQKRQNVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPP 466
            AV A   +RQ +L SATLT+ +  L  ++ + P                     E   P
Sbjct: 174 AAVPA---RRQTLLFSATLTDTLRELQGLATNQPF------------------FWEAQAP 212

Query: 467 PAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFH 526
                    +  E L Q   +VP K++   L   I +     ED  +++F ++C+  +  
Sbjct: 213 --------VSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQ-- 262

Query: 527 YSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTD 586
               L  +L     P              + LH  M+Q+ER A   +F  S   +L+ TD
Sbjct: 263 ---ILCMMLRKFSFPT-------------VALHSMMKQKERFAALAKFKSSIYRILIATD 306

Query: 587 VAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASH 646
           VA+RGLD+P V  ++ +N P  P  YIHR+GRTAR G  G ++ ++   +   V+++   
Sbjct: 307 VASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVHAIEEQ 366

Query: 647 ---KINVSEIKMEDILCVLTR 664
              K+    ++  ++L +LT+
Sbjct: 367 IKKKLEEFSVEEAEVLQILTQ 387


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  189 bits (481), Expect = 7e-48
 Identities = 131/426 (30%), Positives = 216/426 (50%), Gaps = 64/426 (15%)

Query: 213 ELHRPVVKQVQEKVFTSAAFHELGLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDAL 272
           E  +P+V++ + K F      +LG+   L    +  L  +  T +Q ++IP+ L+GRD +
Sbjct: 12  EASQPIVEEEETKTFK-----DLGVTDVLCEACDQ-LGWTKPTKIQIEAIPLALQGRDII 65

Query: 273 VRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPF 332
             ++TGSGKT A+ +P++ +L     ++      +ALVL PTRELA Q  +  + L    
Sbjct: 66  GLAETGSGKTGAFALPILNALLETPQRL------FALVLTPTRELAFQISEQFEALGSSI 119

Query: 333 TWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADR 392
             +   V++GG    S+   L K  +I+I+TPGRL+DH+++TK  +   L++LV DEADR
Sbjct: 120 G-VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADR 178

Query: 393 ILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQ 452
           IL++ FE ++  IL  +  +   R+  L SAT+T+ V +L   +L +PV  +V  K    
Sbjct: 179 ILNMDFETEVDKILKVIPRD---RKTFLFSATMTKKVQKLQRAALKNPVKCAVSSK---- 231

Query: 453 LNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFEEDQK 512
                                 +   E L+Q+   +PSK +   L  +IL +        
Sbjct: 232 ----------------------YQTVEKLQQYYIFIPSKFKDTYLV-YILNELA---GNS 265

Query: 513 MVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQ 572
            ++F S+C   +   +L L+ L  ++                 + LHG M Q +R     
Sbjct: 266 FMIFCSTCNNTQ-RTALLLRNLGFTA-----------------IPLHGQMSQSKRLGSLN 307

Query: 573 EFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLIL 632
           +F    R +LL TDVA+RGLD+P V  +V ++ P+   +YIHR+GRTAR G  G ++  +
Sbjct: 308 KFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFV 367

Query: 633 APSEAE 638
              + E
Sbjct: 368 TQYDVE 373


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  180 bits (457), Expect = 4e-45
 Identities = 177/672 (26%), Positives = 295/672 (43%), Gaps = 91/672 (13%)

Query: 122 RRPPAQASRQAKATKRKYQASSEAPPAKRRNETSFLPAKKTSVKETQRTFKGNAQKMFSP 181
           R+      ++AK+ K + +  ++     +  E      ++ S  E   T   +A +    
Sbjct: 125 RKKRKTEDKEAKSGKLEKEKEAKEGSEPKEQEDLQENDEEGSEDEASETDYSSADENILT 184

Query: 182 KKHSVSTSDRNQEERQCIKTSSLFKNNPDIPELHRPVVKQVQEKVFTSAAFHELGLHPHL 241
           K  ++   DR +++++  +    F++     E               + +F ++ L   L
Sbjct: 185 KADTLKVKDRKKKKKKGQEAGGFFEDASQYDE---------------NLSFQDMNLSRPL 229

Query: 242 ISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQ 301
           +  I T +     T +QK  IPV L G+D    + TG+GKT A+ +PV   L+ +  K +
Sbjct: 230 LKAI-TAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPV---LERLIYKPR 285

Query: 302 RSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILI 361
           ++     LVLVPTREL +Q   +V + L  F  I   + +GG   KS++A LR   +ILI
Sbjct: 286 QAPVTRVLVLVPTRELGIQ-VHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAPDILI 344

Query: 362 STPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVLL 421
           +TPGRL+DH+ +  + H S +  L+ DEADR+LD  FE+ +  I+   +     RQ +L 
Sbjct: 345 ATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCS---HHRQTMLF 401

Query: 422 SATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESL 481
           SAT+T+ V  LA +SL +PV I V   +            +V P               L
Sbjct: 402 SATMTDEVKDLASVSLKNPVRIFVNSNT------------DVAP--------------FL 435

Query: 482 KQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAP 541
           +Q                FI  +   E D++ +V          H  LF QT   +    
Sbjct: 436 RQE---------------FIRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRM- 479

Query: 542 ASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIV 601
               +    M L+   LHG + Q +R    + F   +  +L+ TDVAARGLD+  V  ++
Sbjct: 480 ---HILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVI 536

Query: 602 QYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDILCV 661
            +  P++   Y+HR+GRTAR G  G S+ ++   E + +  +   K   + +K      +
Sbjct: 537 NFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLKEIV--KAAKAPVKAR----I 590

Query: 662 LTRDDCFKGKRWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKALQSFIQA 721
           L +D   K +         +   E    A +     E  +  SE +++ AK+ L+   +A
Sbjct: 591 LPQDVILKFR-------DKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEA 643

Query: 722 YATYPRELKHIFHVRSLHLGHVAKSFGLRDAPRNLSALTRKKRKAHVKRPDLHKK---TQ 778
               P E              +AK+    D    L+   +KKRK  +K  D  KK   T 
Sbjct: 644 VVQEP-ERSWFQTKEERKKEKIAKALQEFD----LALRGKKKRKKFMK--DAKKKGEMTA 696

Query: 779 SKHSLAEILRSE 790
            + S  EIL+++
Sbjct: 697 EERSQFEILKAQ 708


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score =  175 bits (444), Expect = 1e-43
 Identities = 125/395 (31%), Positives = 198/395 (50%), Gaps = 58/395 (14%)

Query: 255 TSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPT 314
           T++Q Q  PV L G D +  +QTGSGKTL+Y +P +  +   +  ++R DGP  LVL PT
Sbjct: 118 TAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHIN-HQPFLERGDGPICLVLAPT 176

Query: 315 RELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKST 374
           RELA Q      +  +    +    + GG  +  +   L +G+ I I+TPGRL+D ++  
Sbjct: 177 RELAQQVQQVAAEYCRACR-LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECG 235

Query: 375 KNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLAD 434
           K  +  R  +LV DEADR+LD+GFE  I  I++ +  +   RQ ++ SAT  + V +LA+
Sbjct: 236 KT-NLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPD---RQTLMWSATWPKEVRQLAE 291

Query: 435 ISLHDPVSISV----LDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPS 490
             L D + I++    L  +H+ L      + +VC     D+                   
Sbjct: 292 DFLKDYIHINIGALELSANHNILQ-----IVDVCHDVEKDE------------------- 327

Query: 491 KLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSAS 550
             +L+ L    +++   E++ K +VF  +    +      L   +   G PA G      
Sbjct: 328 --KLIRL----MEEIMSEKENKTIVFVETKRRCD-----ELTRKMRRDGWPAMG------ 370

Query: 551 MRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPA 610
                  +HG   Q+ER  V  EF H +  +L+ TDVA+RGLD+  V +++ Y+ P+S  
Sbjct: 371 -------IHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSE 423

Query: 611 EYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLAS 645
           +YIHRIGRTAR    G++     P+  + V+ L S
Sbjct: 424 DYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLIS 458


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  174 bits (440), Expect = 4e-43
 Identities = 129/420 (30%), Positives = 203/420 (48%), Gaps = 65/420 (15%)

Query: 231 AFHELGLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVV 290
           AFH     P  +  +      +  T +Q Q  P+ L GRD +  +QTGSGKTLAY +P +
Sbjct: 172 AFHHANF-PQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAI 230

Query: 291 QSLQAMESKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPF---TWIVPGVLMGGEKRK 347
             +   +  ++R DGP  LVL PTRELA Q    VQ++   +   + +    + GG  + 
Sbjct: 231 VHIN-HQPYLERGDGPICLVLAPTRELAQQ----VQQVADDYGKCSRLKSTCIYGGAPKG 285

Query: 348 SEKARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILN 407
            +   L +G+ I I+TPGRL+D ++S K  +  R  +LV DEADR+LD+GFE  I  I++
Sbjct: 286 PQIRDLERGVEICIATPGRLIDFLESGKT-NLRRCTYLVLDEADRMLDMGFEPQIRKIVD 344

Query: 408 AVNAECQKRQNVLLSATLTEGVTRLADISLHDPVSISV----LDKSHDQLNPKDKAVQEV 463
            +  +   RQ ++ SAT  + V +LA+  L D   I+V    L  +H+ L      + +V
Sbjct: 345 QIRPD---RQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQ-----IVDV 396

Query: 464 CPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELV 523
           C              ES K H  +             ++++   E++ K ++F  +    
Sbjct: 397 C-------------MESEKDHKLIQ------------LMEEIMAEKENKTIIFVETKRRC 431

Query: 524 EFHYSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLL 583
           +      L   +   G PA             + +HG   Q ER  V  EF   +  +L+
Sbjct: 432 D-----DLTRRMRRDGWPA-------------MCIHGDKSQPERDWVLNEFRSGKAPILI 473

Query: 584 CTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSL 643
            TDVA+RGLD+  V +++ Y+ P+S  +Y+HRIGRTAR    G++     P   +    L
Sbjct: 474 ATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQAREL 533


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  174 bits (440), Expect = 4e-43
 Identities = 129/420 (30%), Positives = 203/420 (48%), Gaps = 65/420 (15%)

Query: 231 AFHELGLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVV 290
           AFH     P  +  +      +  T +Q Q  P+ L GRD +  +QTGSGKTLAY +P +
Sbjct: 172 AFHHANF-PQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAI 230

Query: 291 QSLQAMESKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPF---TWIVPGVLMGGEKRK 347
             +   +  ++R DGP  LVL PTRELA Q    VQ++   +   + +    + GG  + 
Sbjct: 231 VHIN-HQPYLERGDGPICLVLAPTRELAQQ----VQQVADDYGKCSRLKSTCIYGGAPKG 285

Query: 348 SEKARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILN 407
            +   L +G+ I I+TPGRL+D ++S K  +  R  +LV DEADR+LD+GFE  I  I++
Sbjct: 286 PQIRDLERGVEICIATPGRLIDFLESGKT-NLRRCTYLVLDEADRMLDMGFEPQIRKIVD 344

Query: 408 AVNAECQKRQNVLLSATLTEGVTRLADISLHDPVSISV----LDKSHDQLNPKDKAVQEV 463
            +  +   RQ ++ SAT  + V +LA+  L D   I+V    L  +H+ L      + +V
Sbjct: 345 QIRPD---RQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQ-----IVDV 396

Query: 464 CPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELV 523
           C              ES K H  +             ++++   E++ K ++F  +    
Sbjct: 397 C-------------MESEKDHKLIQ------------LMEEIMAEKENKTIIFVETKRRC 431

Query: 524 EFHYSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLL 583
           +      L   +   G PA             + +HG   Q ER  V  EF   +  +L+
Sbjct: 432 D-----DLTRRMRRDGWPA-------------MCIHGDKSQPERDWVLNEFRSGKAPILI 473

Query: 584 CTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSL 643
            TDVA+RGLD+  V +++ Y+ P+S  +Y+HRIGRTAR    G++     P   +    L
Sbjct: 474 ATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQAREL 533


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  168 bits (426), Expect = 2e-41
 Identities = 140/515 (27%), Positives = 237/515 (46%), Gaps = 93/515 (18%)

Query: 131 QAKATKRKYQASSEAPPAKRRNETSFLPAKKT------SVKETQR--TFKGNAQKMFSPK 182
           Q +  K K +A  E+   K+  E   +           SVKE  +  T+    +  ++P 
Sbjct: 90  QHQHLKEKAEARKESAKEKQLKEEEKILESVAEGRALMSVKEMAKGITYDDPIKTSWTPP 149

Query: 183 KHSVSTSDRNQEERQCIKTSSLFKNNPDIPELHRPVVKQVQEKVFTSAAFHEL---GLHP 239
           ++ +S S+   E  +  K   +      IP    P +K  +E  F +A    L   G+H 
Sbjct: 150 RYVLSMSEERHERVR--KKYHILVEGDGIP----PPIKSFKEMKFPAAILRGLKKKGIH- 202

Query: 240 HLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESK 299
                          T +Q Q IP +L GRD +  + TGSGKTL + +PV+      E +
Sbjct: 203 -------------HPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKR 249

Query: 300 I--QRSDGPYALVLVPTRELALQSFDTVQ---KLLKPFT--WIVPGVLMGGEKRKSEKAR 352
           +   + +GPY L++ P+RELA Q+   ++   +LL+  +   +   + +GG   K +   
Sbjct: 250 LPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMET 309

Query: 353 LRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAE 412
           +R G++++++TPGRL+D ++  K +     R+L  DEADR++D+GFE DI  I +    +
Sbjct: 310 IRHGVHMMVATPGRLMDLLQK-KMVSLDICRYLALDEADRMIDMGFEGDIRTIFSYFKGQ 368

Query: 413 CQKRQNVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKL 472
              RQ +L SAT+ + +   A  +L  PV+I+V       L+     +QEV         
Sbjct: 369 ---RQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLD----VIQEV--------- 412

Query: 473 DSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFF-SSCELVEFHYSLFL 531
                 E +K+   +V             L +C  +    +++F     ++   H  L L
Sbjct: 413 ------EYVKEEAKMV------------YLLECLQKTPPPVLIFAEKKADVDAIHEYLLL 454

Query: 532 QTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARG 591
           +                    ++ + +HGG +QEERT   + F   ++ VL+ TDVA++G
Sbjct: 455 K-------------------GVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKG 495

Query: 592 LDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHG 626
           LD P +  ++ Y+ P     Y+HRIGRT R G  G
Sbjct: 496 LDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTG 530


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  166 bits (420), Expect = 8e-41
 Identities = 110/391 (28%), Positives = 191/391 (48%), Gaps = 54/391 (13%)

Query: 255 TSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPT 314
           T +Q Q+IP ++ GRD +  ++TGSGKT+A+ +P+ + +    S ++  +GP A+++ PT
Sbjct: 396 TPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRS-LEEGEGPIAVIMTPT 454

Query: 315 RELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHI--K 372
           RELALQ     +K  K     V  V  GG     + A L++G  I++ TPGR++D +   
Sbjct: 455 RELALQITKECKKFSKTLGLRVVCV-YGGTGISEQIAELKRGAEIIVCTPGRMIDMLAAN 513

Query: 373 STKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRL 432
           S +  +  R+ ++V DEADR+ D+GFE  +  I++ V  +   RQ V+ SAT    +  L
Sbjct: 514 SGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPD---RQTVMFSATFPRAMEAL 570

Query: 433 ADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKL 492
           A   L  P+ + V  +S                           +   ++Q V V+  + 
Sbjct: 571 ARRILSKPIEVQVGGRS--------------------------VVCSDVEQQVIVIEEEK 604

Query: 493 RLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSASMR 552
           + + L   +     ++E   +++F    E    H    L+ L+ +S              
Sbjct: 605 KFLKLLELL---GHYQESGSVIIFVDKQE----HADGLLKDLMRAS-------------- 643

Query: 553 LKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEY 612
              + LHGG++Q +R ++  +F +    +L+ T VAARGLD+  +  +V Y+ P+   +Y
Sbjct: 644 YPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDY 703

Query: 613 IHRIGRTARIGCHGSSLLILAPSEAEYVNSL 643
           +HR GRT R G  G +   +   +A Y   +
Sbjct: 704 VHRAGRTGRAGNKGYAYTFITEDQARYAGDI 734


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  166 bits (419), Expect = 1e-40
 Identities = 132/452 (29%), Positives = 212/452 (46%), Gaps = 61/452 (13%)

Query: 230 AAFHELGLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPV 289
           ++F   G    L+  I    + +  T +Q Q +PV L GRD +  ++TGSGKT A+  P+
Sbjct: 253 SSFAHFGFDEQLMHQIRKS-EYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPM 311

Query: 290 VQSLQAMESK-IQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKS 348
           +  +  M+ K ++  DGP A+++ PTREL  Q     ++  K +      V  GG   + 
Sbjct: 312 L--IHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ 369

Query: 349 EKARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILNA 408
            KA L++G  I++ TPGRL+DH+K  K  +  R+ +LVFDEADR+ D+GFE  +  I + 
Sbjct: 370 AKA-LQEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEYQVRSIASH 427

Query: 409 VNAECQKRQNVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPA 468
           V  +   RQ +L SAT  + + +LA   L DP+                + VQ       
Sbjct: 428 VRPD---RQTLLFSATFRKKIEKLARDILIDPI----------------RVVQG------ 462

Query: 469 GDKLDSFAIPESLKQHVTVV---PSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEF 525
               D     E + Q V ++   PSK   +               +++V F SS      
Sbjct: 463 ----DIGEANEDVTQIVEILHSGPSKWNWL--------------TRRLVEFTSS------ 498

Query: 526 HYSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCT 585
             S+ L     ++    +  L      L  L  HG M+Q ER  V  +F      VL+ T
Sbjct: 499 -GSVLLFVTKKANAEELANNLKQEGHNLGLL--HGDMDQSERNKVISDFKKKDIPVLVAT 555

Query: 586 DVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLAS 645
           DVAARGLD+P +  ++ Y+       + HRIGRT R G  G +  +L P ++ +   L  
Sbjct: 556 DVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVR 615

Query: 646 HKINVSEIKMEDILCVLTRDDCFKGKRWGAQK 677
           +    ++   +++L +  ++  F+  R+   K
Sbjct: 616 NLEGANQHVSKELLDLAMQNAWFRKSRFKGGK 647


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  166 bits (419), Expect = 1e-40
 Identities = 132/452 (29%), Positives = 212/452 (46%), Gaps = 61/452 (13%)

Query: 230 AAFHELGLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPV 289
           ++F   G    L+  I    + +  T +Q Q +PV L GRD +  ++TGSGKT A+  P+
Sbjct: 253 SSFAHFGFDEQLMHQIRKS-EYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPM 311

Query: 290 VQSLQAMESK-IQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKS 348
           +  +  M+ K ++  DGP A+++ PTREL  Q     ++  K +      V  GG   + 
Sbjct: 312 L--IHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ 369

Query: 349 EKARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILNA 408
            KA L++G  I++ TPGRL+DH+K  K  +  R+ +LVFDEADR+ D+GFE  +  I + 
Sbjct: 370 AKA-LQEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEYQVRSIASH 427

Query: 409 VNAECQKRQNVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPA 468
           V  +   RQ +L SAT  + + +LA   L DP+                + VQ       
Sbjct: 428 VRPD---RQTLLFSATFRKKIEKLARDILIDPI----------------RVVQG------ 462

Query: 469 GDKLDSFAIPESLKQHVTVV---PSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEF 525
               D     E + Q V ++   PSK   +               +++V F SS      
Sbjct: 463 ----DIGEANEDVTQIVEILHSGPSKWNWL--------------TRRLVEFTSS------ 498

Query: 526 HYSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCT 585
             S+ L     ++    +  L      L  L  HG M+Q ER  V  +F      VL+ T
Sbjct: 499 -GSVLLFVTKKANAEELANNLKQEGHNLGLL--HGDMDQSERNKVISDFKKKDIPVLVAT 555

Query: 586 DVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLAS 645
           DVAARGLD+P +  ++ Y+       + HRIGRT R G  G +  +L P ++ +   L  
Sbjct: 556 DVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVR 615

Query: 646 HKINVSEIKMEDILCVLTRDDCFKGKRWGAQK 677
           +    ++   +++L +  ++  F+  R+   K
Sbjct: 616 NLEGANQHVSKELLDLAMQNAWFRKSRFKGGK 647


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score =  164 bits (416), Expect = 2e-40
 Identities = 132/438 (30%), Positives = 203/438 (46%), Gaps = 87/438 (19%)

Query: 231 AFHELGLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVV 290
           ++ +  L PH++  I+        T +Q+Q+IP+ L+ RD +  ++TGSGKT A+ IP++
Sbjct: 392 SWKDSSLPPHILEVIDKC-GYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLL 450

Query: 291 QSLQAME--SKIQRSD-GPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRK 347
             +  +    +I+ SD GPYA++L PTRELA Q  +   K  KP   I    ++GG  R+
Sbjct: 451 VWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPL-GIRTVAVIGGISRE 509

Query: 348 SEKARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILN 407
            +  RLR G  I+I+TPGRL+D +   + +  SR  ++V DEADR++D+GFE D+  IL 
Sbjct: 510 DQGFRLRMGCEIVIATPGRLID-VLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILE 568

Query: 408 AVNAECQK-----------------------RQNVLLSATLTEGVTRLADISLHDP--VS 442
            +    QK                       RQ V+ +AT+   V RLA   L  P  V 
Sbjct: 569 HMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVY 628

Query: 443 ISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFIL 502
           I    K H+++  K                  F + ES K+       KL  +    F  
Sbjct: 629 IGSAGKPHERVEQK-----------------VFLMSESEKR------KKLLAILEQGF-- 663

Query: 503 QKCKFEEDQKMVVFFS---SCELVEFHYSLFLQTLLSSSGAPASGQLPSASMRLKFLRLH 559
                  D  +++F +    C++        L   L   G  A               LH
Sbjct: 664 -------DPPIIIFVNQKKGCDV--------LAKSLEKMGYNA-------------CTLH 695

Query: 560 GGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRT 619
           GG  QE+R           + +L+ TDVA RG+D+  V+ +V Y+   +  +YIHRIGRT
Sbjct: 696 GGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRT 755

Query: 620 ARIGCHGSSLLILAPSEA 637
            R G  G ++  L   ++
Sbjct: 756 GRAGKSGVAITFLTKEDS 773


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  162 bits (411), Expect = 9e-40
 Identities = 122/437 (27%), Positives = 216/437 (49%), Gaps = 62/437 (14%)

Query: 210 DIPELHRPVVKQVQEKVFTSAAFHELGL-HPHLISTINTVLKMSSMTSVQKQSIPVLLEG 268
           D+    R +V+   +K   S  F  +GL +P     +    K+   T +Q+++IPV+L+G
Sbjct: 76  DVEPDTREMVRAQNKKKKKSGGFQSMGLSYPVFKGIMKKGYKVP--TPIQRKTIPVILDG 133

Query: 269 RDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPTRELALQSFDTVQKL 328
           +D +  ++TGSGKT  + +P+ + L+   ++     G  AL+L PTRELALQ+    ++L
Sbjct: 134 KDVVAMARTGSGKTACFLLPMFERLKTHSAQ----TGARALILSPTRELALQTLKFTKEL 189

Query: 329 LKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFD 388
            K FT +   +++GG++ + + A L +  +I+I+TPGRLV H+    ++    + ++VFD
Sbjct: 190 GK-FTGLKTALILGGDRMEDQFAALHENPDIIIATPGRLV-HVAVEMSLKLQSVEYVVFD 247

Query: 389 EADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADISLHDPVSI--SVL 446
           EADR+ ++GF + +  I+  +       Q VL SATL + +   A   L +PV I   V 
Sbjct: 248 EADRLFEMGFAEQLQEIIARLPG---GHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVD 304

Query: 447 DKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCK 506
            K ++QL                 K   F + E  K  V +             +L    
Sbjct: 305 TKLNEQL-----------------KTSFFLVREDTKAAVLL------------HLLHNVV 335

Query: 507 FEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEE 566
             +DQ +V   +       H++ +L  LL+             + R+    ++  ++   
Sbjct: 336 RPQDQTVVFVATK------HHAEYLTELLT-------------TQRVSCAHIYSALDPTA 376

Query: 567 RTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHG 626
           R     +F+  +   L+ TD+AARGLD+P +  ++ Y+ P+    ++HR+GR AR G  G
Sbjct: 377 RKINLAKFTLGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSG 436

Query: 627 SSLLILAPSEAEYVNSL 643
           ++  ++AP E  Y+  L
Sbjct: 437 TAYSLVAPDEIPYLLDL 453


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  162 bits (411), Expect = 9e-40
 Identities = 122/437 (27%), Positives = 216/437 (49%), Gaps = 62/437 (14%)

Query: 210 DIPELHRPVVKQVQEKVFTSAAFHELGL-HPHLISTINTVLKMSSMTSVQKQSIPVLLEG 268
           D+    R +V+   +K   S  F  +GL +P     +    K+   T +Q+++IPV+L+G
Sbjct: 76  DVEPDTREMVRAQNKKKKKSGGFQSMGLSYPVFKGIMKKGYKVP--TPIQRKTIPVILDG 133

Query: 269 RDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPTRELALQSFDTVQKL 328
           +D +  ++TGSGKT  + +P+ + L+   ++     G  AL+L PTRELALQ+    ++L
Sbjct: 134 KDVVAMARTGSGKTACFLLPMFERLKTHSAQ----TGARALILSPTRELALQTLKFTKEL 189

Query: 329 LKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFD 388
            K FT +   +++GG++ + + A L +  +I+I+TPGRLV H+    ++    + ++VFD
Sbjct: 190 GK-FTGLKTALILGGDRMEDQFAALHENPDIIIATPGRLV-HVAVEMSLKLQSVEYVVFD 247

Query: 389 EADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADISLHDPVSI--SVL 446
           EADR+ ++GF + +  I+  +       Q VL SATL + +   A   L +PV I   V 
Sbjct: 248 EADRLFEMGFAEQLQEIIARLPG---GHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVD 304

Query: 447 DKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCK 506
            K ++QL                 K   F + E  K  V +             +L    
Sbjct: 305 TKLNEQL-----------------KTSFFLVREDTKAAVLL------------HLLHNVV 335

Query: 507 FEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEE 566
             +DQ +V   +       H++ +L  LL+             + R+    ++  ++   
Sbjct: 336 RPQDQTVVFVATK------HHAEYLTELLT-------------TQRVSCAHIYSALDPTA 376

Query: 567 RTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHG 626
           R     +F+  +   L+ TD+AARGLD+P +  ++ Y+ P+    ++HR+GR AR G  G
Sbjct: 377 RKINLAKFTLGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSG 436

Query: 627 SSLLILAPSEAEYVNSL 643
           ++  ++AP E  Y+  L
Sbjct: 437 TAYSLVAPDEIPYLLDL 453


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  159 bits (402), Expect = 1e-38
 Identities = 126/420 (30%), Positives = 199/420 (47%), Gaps = 56/420 (13%)

Query: 255 TSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPT 314
           T +Q Q+ P++L+G D +  +QTG+GKTL Y +P    L    S   + + P  LVL PT
Sbjct: 266 TPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKGQRNRPGMLVLTPT 325

Query: 315 RELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKST 374
           RELALQ      K    +  +    + GG  R  +   L+KG++I+I+TPGRL D ++ +
Sbjct: 326 RELALQVEGECCKY--SYKGLRSVCVYGGGNRDEQIEELKKGVDIIIATPGRLND-LQMS 382

Query: 375 KNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLAD 434
             ++   + +LV DEAD++LD+GFE  I  IL  V  +   RQ V+ SAT    V RLA 
Sbjct: 383 NFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPD---RQTVMTSATWPHSVHRLAQ 439

Query: 435 ISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRL 494
             L +P+ + V                          LD  A+  S+KQ++ V   + + 
Sbjct: 440 SYLKEPMIVYV------------------------GTLDLVAV-SSVKQNIIVTTEEEKW 474

Query: 495 VCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYS--LFLQTLLSSSGAPASGQLPSASMR 552
             +  F+      ++    V+ F S + V  H S  L L  +   S              
Sbjct: 475 SHMQTFLQSMSSTDK----VIVFVSRKAVADHLSSDLILGNISVES-------------- 516

Query: 553 LKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEY 612
                LHG  EQ +R    + F   +  +L+ TD+A+RGLD+  VT +  ++ P +  EY
Sbjct: 517 -----LHGDREQRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEY 571

Query: 613 IHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDILCVLTRDDCFKGKR 672
           +HRIGRT R G  G S+  L  ++    + L +     ++   E+++ +  R    + KR
Sbjct: 572 VHRIGRTGRAGRTGVSITTLTRNDWRVASELINILERANQSIPEELVSMAERFKAHQQKR 631


>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
           sapiens]
          Length = 631

 Score =  155 bits (393), Expect = 1e-37
 Identities = 122/445 (27%), Positives = 209/445 (46%), Gaps = 53/445 (11%)

Query: 238 HPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAME 297
           +P L+ +I  V  +   T +Q Q+ P++L+G D +V +QTG+GKTL+Y +P    L +  
Sbjct: 230 YPDLLKSIIRV-GIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQP 288

Query: 298 SKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGI 357
              ++ +GP  LVL PTRELAL       K    +  +    + GG  R  +   + KG+
Sbjct: 289 ISREQRNGPGMLVLTPTRELALHVEAECSKY--SYKGLKSICIYGGRNRNGQIEDISKGV 346

Query: 358 NILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQ 417
           +I+I+TPGRL D ++   +++   + +LV DEAD++LD+ FE  I  IL  V  +   RQ
Sbjct: 347 DIIIATPGRLND-LQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPD---RQ 402

Query: 418 NVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAI 477
            V+ SAT  + V +LA   L DP+ + V                          L+  A+
Sbjct: 403 TVMTSATWPDTVRQLALSYLKDPMIVYV------------------------GNLNLVAV 438

Query: 478 PESLKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSS 537
             ++KQ++ V   K +      F+        + K+++F S     + H +  L +  + 
Sbjct: 439 -NTVKQNIIVTTEKEKRALTQEFVE---NMSPNDKVIMFVS-----QKHIADDLSSDFNI 489

Query: 538 SGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQV 597
            G  A               LHG  EQ ++    ++F      +L+ TD+ +RGLDL  V
Sbjct: 490 QGISAES-------------LHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDV 536

Query: 598 TWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMED 657
           T +  Y+ P +   Y+HR+G   R G  G+S+ ++   +++    L       ++   ED
Sbjct: 537 THVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRANQSVPED 596

Query: 658 ILCVLTRDDCFKGKRWGAQKSHAVG 682
           ++ +  +    + KR    +S   G
Sbjct: 597 LVVMAEQYKLNQQKRHRETRSRKPG 621


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score =  155 bits (391), Expect = 2e-37
 Identities = 157/598 (26%), Positives = 259/598 (43%), Gaps = 79/598 (13%)

Query: 68  SGPGRGGGAGSSRVPRGVPGPAVCAPGSLLHHASPTQTMAAADGSLFDNPRTFSRRPPAQ 127
           SGP R GG GS R  RG  G      GS  +   P + M    G LF      SRRP   
Sbjct: 142 SGPYRRGGRGSFRGCRGGFGL-----GSPNNDLDPDECMQRT-GGLFG-----SRRPVLS 190

Query: 128 ASRQAKATKRKYQASSEAPPAKRRNETSFLPAKKTSVKETQRTFKGNAQKMFSPKKHSVS 187
            +     ++ +  + SE    K  NE     + K S K       G +     PK   + 
Sbjct: 191 GTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEG--GESSDTQGPKVTYIP 248

Query: 188 TSDRNQEERQCIKTSSLFKNNPDIPELHRPVVKQVQEKVFTSAAFHELGLHPHLISTINT 247
                 E+       + ++   +  +    +V+        +    E     +L  T+N 
Sbjct: 249 PPPPEDED----SIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFE---EANLCQTLNN 301

Query: 248 VLKMSS---MTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQ---AMESKIQ 301
            +  +    +T VQK SIP++L GRD +  +QTGSGKT A+ +P++  +       S+ +
Sbjct: 302 NIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFK 361

Query: 302 RSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILI 361
               P  +++ PTREL  Q +   +K     T +   V+ GG +      ++ +G NIL 
Sbjct: 362 ELQEPECIIVAPTRELVNQIYLEARK-FSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420

Query: 362 STPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAEC-QKRQNVL 420
           +TPGRL+D I   K I   ++++LV DEADR+LD+GF  ++  +++       ++RQ ++
Sbjct: 421 ATPGRLMDIIGKEK-IGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLM 479

Query: 421 LSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPES 480
            SAT  E + RLA   L      + L  +  Q+    + VQ+        ++  F+  E 
Sbjct: 480 FSATFPEEIQRLAAEFLKS----NYLFVAVGQVGGACRDVQQTVL-----QVGQFSKREK 530

Query: 481 LKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGA 540
           L + +  +                     D++ +VF  + +  +F  +   Q  +S++  
Sbjct: 531 LVEILRNI--------------------GDERTMVFVETKKKADFIATFLCQEKISTTS- 569

Query: 541 PASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWI 600
                            +HG  EQ ER     +F   +  VL+ T VAARGLD+  V  +
Sbjct: 570 -----------------IHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHV 612

Query: 601 VQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDI 658
           + ++ PS+  EY+HRIGRT R G  G ++      + E  N LA   + V     +D+
Sbjct: 613 INFDLPSTIDEYVHRIGRTGRCGNTGRAISFF---DLESDNHLAQPLVKVLTDAQQDV 667


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score =  155 bits (391), Expect = 2e-37
 Identities = 157/598 (26%), Positives = 259/598 (43%), Gaps = 79/598 (13%)

Query: 68  SGPGRGGGAGSSRVPRGVPGPAVCAPGSLLHHASPTQTMAAADGSLFDNPRTFSRRPPAQ 127
           SGP R GG GS R  RG  G      GS  +   P + M    G LF      SRRP   
Sbjct: 142 SGPYRRGGRGSFRGCRGGFGL-----GSPNNDLDPDECMQRT-GGLFG-----SRRPVLS 190

Query: 128 ASRQAKATKRKYQASSEAPPAKRRNETSFLPAKKTSVKETQRTFKGNAQKMFSPKKHSVS 187
            +     ++ +  + SE    K  NE     + K S K       G +     PK   + 
Sbjct: 191 GTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEG--GESSDTQGPKVTYIP 248

Query: 188 TSDRNQEERQCIKTSSLFKNNPDIPELHRPVVKQVQEKVFTSAAFHELGLHPHLISTINT 247
                 E+       + ++   +  +    +V+        +    E     +L  T+N 
Sbjct: 249 PPPPEDED----SIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFE---EANLCQTLNN 301

Query: 248 VLKMSS---MTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQ---AMESKIQ 301
            +  +    +T VQK SIP++L GRD +  +QTGSGKT A+ +P++  +       S+ +
Sbjct: 302 NIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFK 361

Query: 302 RSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILI 361
               P  +++ PTREL  Q +   +K     T +   V+ GG +      ++ +G NIL 
Sbjct: 362 ELQEPECIIVAPTRELVNQIYLEARK-FSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420

Query: 362 STPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAEC-QKRQNVL 420
           +TPGRL+D I   K I   ++++LV DEADR+LD+GF  ++  +++       ++RQ ++
Sbjct: 421 ATPGRLMDIIGKEK-IGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLM 479

Query: 421 LSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPES 480
            SAT  E + RLA   L      + L  +  Q+    + VQ+        ++  F+  E 
Sbjct: 480 FSATFPEEIQRLAAEFLKS----NYLFVAVGQVGGACRDVQQTVL-----QVGQFSKREK 530

Query: 481 LKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGA 540
           L + +  +                     D++ +VF  + +  +F  +   Q  +S++  
Sbjct: 531 LVEILRNI--------------------GDERTMVFVETKKKADFIATFLCQEKISTTS- 569

Query: 541 PASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWI 600
                            +HG  EQ ER     +F   +  VL+ T VAARGLD+  V  +
Sbjct: 570 -----------------IHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHV 612

Query: 601 VQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDI 658
           + ++ PS+  EY+HRIGRT R G  G ++      + E  N LA   + V     +D+
Sbjct: 613 INFDLPSTIDEYVHRIGRTGRCGNTGRAISFF---DLESDNHLAQPLVKVLTDAQQDV 667


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  154 bits (389), Expect = 3e-37
 Identities = 130/470 (27%), Positives = 215/470 (45%), Gaps = 71/470 (15%)

Query: 172 KGNAQKMFSPKKHSVSTSDRNQEERQCIKTSSLFKNNPDIPELHRPVVKQVQEKVFTSAA 231
           K    K+ +P+K        + E    +  S ++K +P I  L    ++ +++++     
Sbjct: 142 KEEKSKLSNPQK-------ADSEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQ 194

Query: 232 FHELGL------HPHLISTINTVLKMSSM---TSVQKQSIPVLLEGRDALVRSQTGSGKT 282
             E+        H  L   +N  LK S     T +Q Q IPV L GRD L  + TGSGKT
Sbjct: 195 GQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKT 254

Query: 283 LAYCIPVVQSLQAMESKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMG 342
            A+ +PV+      ESK      P AL+L PTRELA+Q     ++L+     +   +L+G
Sbjct: 255 AAFLLPVIMRA-LFESKT-----PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVG 308

Query: 343 GEKRKSEKARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDI 402
           G     +  RL++ + ++I+TPGRL+D IK + ++    ++ +V DEAD +L +GF++ +
Sbjct: 309 GLPLPPQLYRLQQHVKVIIATPGRLLDIIKQS-SVELCGVKIVVVDEADTMLKMGFQQQV 367

Query: 403 TVILNAVNAECQKRQNVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQE 462
             IL  +  +C   Q +L+SAT+   + +LA   LH+PV I   +K+    N        
Sbjct: 368 LDILENIPNDC---QTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCAN-------- 416

Query: 463 VCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCEL 522
                             ++Q +  V    +   L   +  K  F+     V+ F  C+L
Sbjct: 417 ------------------VRQIILWVEDPAKKKKLFEILNDKKLFKPP---VLVFVDCKL 455

Query: 523 VEFHYSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVL 582
                           GA    +       LK + +H    Q ER  + +        V+
Sbjct: 456 ----------------GADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVV 499

Query: 583 LCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLIL 632
           + T V  RGLDL  V  +V ++ PSS  EY+H+IGR  R+G +G+++  +
Sbjct: 500 VSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFI 549


>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
           [Homo sapiens]
          Length = 690

 Score =  150 bits (380), Expect = 4e-36
 Identities = 117/411 (28%), Positives = 197/411 (47%), Gaps = 56/411 (13%)

Query: 252 SSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQ---AMESKIQRSDGPYA 308
           + +T VQK SIP++L GRD +  +QTGSGKT A+ +P++  +       S+ +    P  
Sbjct: 275 TKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPEC 334

Query: 309 LVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLV 368
           +++ PTREL  Q +   +K     T +   V+ GG +      ++ +G NIL +TPGRL+
Sbjct: 335 IIVAPTRELVNQIYLEARK-FSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLM 393

Query: 369 DHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAEC-QKRQNVLLSATLTE 427
           D I   K I   ++++LV DEADR+LD+GF  ++  +++       ++RQ ++ SAT  E
Sbjct: 394 DIIGKEK-IGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPE 452

Query: 428 GVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTV 487
            + RLA   L      + L  +  Q+    + VQ+        ++  F+  E L + +  
Sbjct: 453 EIQRLAAEFLKS----NYLFVAVGQVGGACRDVQQTVL-----QVGQFSKREKLVEILRN 503

Query: 488 VPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLP 547
           +                     D++ +VF  + +  +F  +   Q  +S++         
Sbjct: 504 I--------------------GDERTMVFVETKKKADFIATFLCQEKISTTS-------- 535

Query: 548 SASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPS 607
                     +HG  EQ ER     +F   +  VL+ T VAARGLD+  V  ++ ++ PS
Sbjct: 536 ----------IHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPS 585

Query: 608 SPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDI 658
           +  EY+HRIGRT R G  G ++      + E  N LA   + V     +D+
Sbjct: 586 TIDEYVHRIGRTGRCGNTGRAISFF---DLESDNHLAQPLVKVLTDAQQDV 633


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score =  149 bits (377), Expect = 8e-36
 Identities = 136/534 (25%), Positives = 240/534 (44%), Gaps = 82/534 (15%)

Query: 126 AQASRQAKATKRK---YQASSEAPPAKRRNETSFLPAKKTSVKETQRTFKGNAQKMFS-- 180
           +Q   + K+ +RK   +  S E    +    T  L A K    + +    G+ ++ F+  
Sbjct: 22  SQKKERQKSDRRKSRHHYDSDEKSETRENGVTDDLDAPKAKKSKMKEKLNGDTEEGFNRL 81

Query: 181 ---------PKKHSVSTSDRNQEERQCIKTSSLFKNNPDIPE--LHRPVVKQVQEKVFTS 229
                     ++  +   D ++ E++  + SSL  +     +  L   + ++ +E  F++
Sbjct: 82  SDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHKSSDNKLEETLTREQKEGAFSN 141

Query: 230 AAFHELGLHPHLISTINTVLKMSSMT---SVQKQSIPVLLEGRDALVRSQTGSGKTLAYC 286
               E         TI  +LK   +T    +Q ++   + EG+D + +++TG+GKT ++ 
Sbjct: 142 FPISE--------ETIK-LLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFA 192

Query: 287 IPVVQSLQAMESKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFT-WIVPGVLMGGEK 345
           IP+++ LQ  +  I++S  P  LVL PTRELA Q    V K  K  T  +      GG  
Sbjct: 193 IPLIERLQRNQETIKKSRSPKVLVLAPTRELANQ----VAKDFKDITRKLSVACFYGGTS 248

Query: 346 RKSEKARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVI 405
            +S+   +R GI+IL+ TPGR+ DH++S + +  S+LR +V DE D++LDLGF + +  I
Sbjct: 249 YQSQINHIRNGIDILVGTPGRIKDHLQSGR-LDLSKLRHVVLDEVDQMLDLGFAEQVEDI 307

Query: 406 LN---AVNAECQKRQNVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQE 462
           ++     ++E    Q +L SAT  + V ++A            +   ++Q++   K  Q+
Sbjct: 308 IHESYKTDSE-DNPQTLLFSATCPQWVYKVAK---------KYMKSRYEQVDLVGKMTQK 357

Query: 463 VCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCEL 522
                A   ++  AI     Q   V+   L++               + + ++F   CE 
Sbjct: 358 -----AATTVEHLAIQCHWSQRPAVIGDVLQVYS-----------GSEGRAIIF---CET 398

Query: 523 VEFHYSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVL 582
            +    + +   +  +                   LHG + Q +R    + F      VL
Sbjct: 399 KKNVTEMAMNPHIKQNAQ----------------CLHGDIAQSQREITLKGFREGSFKVL 442

Query: 583 LCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSE 636
           + T+VAARGLD+P+V  ++Q + P     YIHR GRT R G  G  +    P E
Sbjct: 443 VATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFYQPRE 496


>gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens]
          Length = 547

 Score =  140 bits (353), Expect = 5e-33
 Identities = 155/600 (25%), Positives = 257/600 (42%), Gaps = 126/600 (21%)

Query: 232 FHELGLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQ 291
           F  +GL P L+  + T L  S  T +Q+++IP+ LEG+D L R++TGSGKT AY IP++Q
Sbjct: 9   FEHMGLDPRLLQAV-TDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQ 67

Query: 292 SLQAMESKIQRSDGPY------ALVLVPTRELALQSFDTVQKLLKPFTWIVPGV----LM 341
            L       +++ GP        LVLVPT+ELA Q+   +Q+L    T+    V    + 
Sbjct: 68  LLLH-----RKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLA---TYCARDVRVANVS 119

Query: 342 GGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKD 401
             E   S++A L +  ++++ TP R++ H++         L  LV DEAD +   GFE++
Sbjct: 120 AAEDSVSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEE 179

Query: 402 ITVILNAVNAECQKRQNVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQ 461
           +  +L  +    +  Q  L+SAT  E V  L ++ LH+PV++ +      QL        
Sbjct: 180 LKSLLCHLP---RIYQAFLMSATFNEDVQALKELILHNPVTLKL---QESQL-------- 225

Query: 462 EVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVF-FSSC 520
                P  D+L  F +                           C+ EED+ ++++     
Sbjct: 226 -----PGPDQLQQFQV--------------------------VCETEEDKFLLLYALLKL 254

Query: 521 ELVEFHYSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRG 580
            L+     LF+ TL  S       +L      +    L+G +    R  +  +F+     
Sbjct: 255 SLIRGKSLLFVNTLERSYRL----RLFLEQFSIPTCVLNGELPLRSRCHIISQFNQGFYD 310

Query: 581 VLLCTDV---------------------------AARGLDLPQVTWIVQYNAPSSPAEYI 613
            ++ TD                             ARG+D   V+ ++ ++ P +P  YI
Sbjct: 311 CVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTPEAYI 370

Query: 614 HRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDILCVLTRDDCFKGKRW 673
           HR GRTAR    G  L  + P+E  ++  +   ++   E +   +L    R +  +G R+
Sbjct: 371 HRAGRTARANNPGIVLTFVLPTEQFHLGKI--EELLSGENRGPILLPYQFRMEEIEGFRY 428

Query: 674 GAQKS-HAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKALQSFIQAYATYPRELKHI 732
             + +  +V  Q IRE    L+ + E+ +HS + +              +   PR+L+ +
Sbjct: 429 RCRDAMRSVTKQAIREAR--LKEIKEELLHSEKLKT------------YFEDNPRDLQLL 474

Query: 733 FH-------VRSLHLGHVAKSFGLRDAPRNLSALTR--KKRKAHVKRPDLHKKTQSKHSL 783
            H       V   HLGHV         P  L  L R  KKRK         K+ +S++ L
Sbjct: 475 RHDLPLHPAVVKPHLGHVPDYL----VPPALRGLVRPHKKRKKLSSSCRKAKRAKSQNPL 530


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score =  138 bits (347), Expect = 2e-32
 Identities = 105/372 (28%), Positives = 172/372 (46%), Gaps = 50/372 (13%)

Query: 257 VQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPTRE 316
           +Q ++   +  G+D + +++TG+GKT ++ IP+++ L       +R   P  LVL PTRE
Sbjct: 212 IQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRE 271

Query: 317 LALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKN 376
           LA Q       + K  +        GG     +  R+R GI+IL+ TPGR+ DHI++ K 
Sbjct: 272 LANQVSKDFSDITKKLS---VACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGK- 327

Query: 377 IHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQK--RQNVLLSATLTEGVTRLAD 434
           +  ++L+ +V DE D++LD+GF   +  IL+    +  +   Q +L SAT    V  +A 
Sbjct: 328 LDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAK 387

Query: 435 ISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRL 494
                      +  +++Q++   K  Q+         ++  AI     Q   V+   +R+
Sbjct: 388 ---------KYMKSTYEQVDLIGKKTQK-----TAITVEHLAIKCHWTQRAAVIGDVIRV 433

Query: 495 VCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSASMRLK 554
                       +   Q   + F  CE  +       Q L  +S      Q         
Sbjct: 434 ------------YSGHQGRTIIF--CETKK-----EAQELSQNSAIKQDAQ--------- 465

Query: 555 FLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYIH 614
              LHG + Q++R    + F +   GVL+ T+VAARGLD+P+V  ++Q + P     YIH
Sbjct: 466 --SLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIH 523

Query: 615 RIGRTARIGCHG 626
           R GRT R G  G
Sbjct: 524 RSGRTGRAGRTG 535


>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
           [Homo sapiens]
          Length = 406

 Score =  132 bits (332), Expect = 1e-30
 Identities = 82/236 (34%), Positives = 136/236 (57%), Gaps = 16/236 (6%)

Query: 213 ELHRPVVKQVQEKVFTSAAFHELGLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDAL 272
           E  +P+V++ + K F      +LG+   L    +  L  +  T +Q ++IP+ L+GRD +
Sbjct: 12  EASQPIVEEEETKTFK-----DLGVTDVLCEACDQ-LGWTKPTKIQIEAIPLALQGRDII 65

Query: 273 VRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPF 332
             ++TGSGKT A+ +P++ +L     ++      +ALVL PTRELA Q  +  + L    
Sbjct: 66  GLAETGSGKTGAFALPILNALLETPQRL------FALVLTPTRELAFQISEQFEALGSSI 119

Query: 333 TWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADR 392
             +   V++GG    S+   L K  +I+I+TPGRL+DH+++TK  +   L++LV DEADR
Sbjct: 120 G-VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADR 178

Query: 393 ILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADISLHDPVSISVLDK 448
           IL++ FE ++  IL  +  +   R+  L SAT+T+ V +L   +L +PV  +V  K
Sbjct: 179 ILNMDFETEVDKILKVIPRD---RKTFLFSATMTKKVQKLQRAALKNPVKCAVSSK 231



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 29/75 (38%), Positives = 45/75 (60%)

Query: 564 QEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIG 623
           + +R     +F    R +LL TDVA+RGLD+P V  +V ++ P+   +YIHR+GRTAR G
Sbjct: 250 KSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAG 309

Query: 624 CHGSSLLILAPSEAE 638
             G ++  +   + E
Sbjct: 310 RSGKAITFVTQYDVE 324


>gi|8922976 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 [Homo sapiens]
          Length = 540

 Score =  129 bits (325), Expect = 9e-30
 Identities = 123/414 (29%), Positives = 189/414 (45%), Gaps = 57/414 (13%)

Query: 225 KVFTSAAFHELGLHPHLISTINTVL-KMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTL 283
           K+ +  +F +LGL P ++  +     ++   T+VQ  +IP LL GR  +  ++TGSGKTL
Sbjct: 121 KLSSKGSFADLGLEPRVLHALQEAAPEVVQPTTVQSSTIPSLLRGRHVVCAAETGSGKTL 180

Query: 284 AYCIPVVQSLQAMESKIQRS-DGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMG 342
           +Y +P++Q L    S        P  LVLVP+RELA Q     Q L +    +V   L G
Sbjct: 181 SYLLPLLQRLLGQPSLDSLPIPAPRGLVLVPSRELAQQVRAVAQPLGRSLGLLVRD-LEG 239

Query: 343 GEKRKSEKARLRK--GINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEK 400
           G   +  + +L +    ++L++TPG L   +KS + I   +L +LV DEAD +LD  F +
Sbjct: 240 GHGMRRIRLQLSRQPSADVLVATPGALWKALKS-RLISLEQLSFLVLDEADTLLDESFLE 298

Query: 401 DITVILNAVN-----AECQ-----KRQNVLLSATLTEGVTRLAD-ISLHDPVSISVLDKS 449
            +  IL   +     A+ +     K Q VL+ AT  EGV +L + ++  D V+     K 
Sbjct: 299 LVDYILEKSHIAEGPADLEDPFNPKAQLVLVGATFPEGVGQLLNKVASPDAVTTITSSKL 358

Query: 450 HDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFEE 509
           H  + P  K  Q        DK+           H+     +      +  +L  C    
Sbjct: 359 H-CIMPHVK--QTFLRLKGADKVAELV-------HILKHRDRAERTGPSGTVLVFCNSSS 408

Query: 510 DQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTA 569
               + +      ++ H  L              GQ+P A MR+                
Sbjct: 409 TVNWLGYILDDHKIQ-HLRL-------------QGQMP-ALMRV---------------G 438

Query: 570 VFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIG 623
           +FQ F  S R +LLCTD+A+RGLD   V  +V Y+ P +  +YIHR GR  R+G
Sbjct: 439 IFQSFQKSSRDILLCTDIASRGLDSTGVELVVNYDFPPTLQDYIHRAGRVGRVG 492


>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score =  129 bits (324), Expect = 1e-29
 Identities = 98/376 (26%), Positives = 173/376 (46%), Gaps = 59/376 (15%)

Query: 257 VQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPTRE 316
           +Q++SIP+ L GRD L R++ G+GK+ AY IP+++ L   +  IQ      A+V+VPTRE
Sbjct: 122 IQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQ------AMVIVPTRE 175

Query: 317 LALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKN 376
           LALQ      ++ K           GG   + +  RL   ++++I+TPGR++D IK    
Sbjct: 176 LALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGV- 234

Query: 377 IHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADIS 436
                ++ +V DEAD++L   F   + ++ + +    + RQ +L SAT    V +  +  
Sbjct: 235 AKVDHVQMIVLDEADKLLSQDF---VQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSH 291

Query: 437 LHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVC 496
           L  P  I+++++                              + + Q+   V  + ++ C
Sbjct: 292 LQKPYEINLMEE---------------------------LTLKGVTQYYAYVTERQKVHC 324

Query: 497 LAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSASMRLKFL 556
           L     +     +  + ++F +S + VE      L   +S  G                 
Sbjct: 325 LNTLFSRL----QINQSIIFCNSSQRVE-----LLAKKISQLG-------------YSCF 362

Query: 557 RLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRI 616
            +H  M QE R  VF +F +     L+CTD+  RG+D+  V  ++ ++ P     Y+HRI
Sbjct: 363 YIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRI 422

Query: 617 GRTARIGCHGSSLLIL 632
           GR+ R G  G ++ ++
Sbjct: 423 GRSGRFGHLGLAINLI 438


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,132,584
Number of Sequences: 37866
Number of extensions: 1819599
Number of successful extensions: 10602
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 457
Number of HSP's that attempted gapping in prelim test: 9188
Number of HSP's gapped (non-prelim): 1553
length of query: 851
length of database: 18,247,518
effective HSP length: 111
effective length of query: 740
effective length of database: 14,044,392
effective search space: 10392850080
effective search space used: 10392850080
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.