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Search of human proteins with 171460948
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo
sapiens]
(1073 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] 2078 0.0
gi|7662236 TSC22 domain family, member 2 [Homo sapiens] 252 1e-66
gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens] 202 2e-51
gi|37622901 TSC22 domain family, member 3 isoform 2 [Homo sapiens] 127 6e-29
gi|37622903 TSC22 domain family, member 3 isoform 1 [Homo sapiens] 125 3e-28
gi|13569901 TSC22 domain family, member 4 [Homo sapiens] 114 6e-25
gi|62865625 TSC22 domain family, member 3 isoform 3 [Homo sapiens] 97 1e-19
gi|91982772 mucin 17 [Homo sapiens] 91 4e-18
gi|167736355 mucin 4 isoform a [Homo sapiens] 88 4e-17
gi|56549696 E1A binding protein p400 [Homo sapiens] 87 8e-17
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 87 8e-17
gi|38788274 bromodomain PHD finger transcription factor isoform ... 83 1e-15
gi|225579127 Sin3A-associated protein, 130kDa isoform a [Homo sa... 82 4e-15
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 80 8e-15
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 76 1e-13
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 76 1e-13
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 76 1e-13
gi|162951884 R3H domain containing 2 [Homo sapiens] 74 6e-13
gi|150170670 piccolo isoform 2 [Homo sapiens] 74 1e-12
gi|150378539 piccolo isoform 1 [Homo sapiens] 74 1e-12
gi|119943102 CREB binding protein isoform b [Homo sapiens] 73 1e-12
gi|119943104 CREB binding protein isoform a [Homo sapiens] 73 1e-12
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] 72 3e-12
gi|19923597 Sin3A-associated protein, 130kDa isoform b [Homo sap... 71 5e-12
gi|56549668 AT rich interactive domain 2 (ARID, RFX-like) [Homo ... 71 5e-12
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 71 6e-12
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 71 6e-12
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 71 6e-12
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom... 70 1e-11
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo... 70 1e-11
>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
Length = 1073
Score = 2078 bits (5384), Expect = 0.0
Identities = 1073/1073 (100%), Positives = 1073/1073 (100%)
Query: 1 MHQPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPP 60
MHQPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPP
Sbjct: 1 MHQPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPP 60
Query: 61 PSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQ 120
PSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQ
Sbjct: 61 PSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQ 120
Query: 121 ISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNF 180
ISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNF
Sbjct: 121 ISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNF 180
Query: 181 QEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPS 240
QEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPS
Sbjct: 181 QEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPS 240
Query: 241 HVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTG 300
HVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTG
Sbjct: 241 HVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTG 300
Query: 301 GIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVN 360
GIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVN
Sbjct: 301 GIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVN 360
Query: 361 VNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFK 420
VNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFK
Sbjct: 361 VNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFK 420
Query: 421 KGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHY 480
KGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHY
Sbjct: 421 KGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHY 480
Query: 481 TESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS 540
TESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS
Sbjct: 481 TESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS 540
Query: 541 QSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSL 600
QSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSL
Sbjct: 541 QSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSL 600
Query: 601 AQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQ 660
AQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQ
Sbjct: 601 AQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQ 660
Query: 661 PILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAV 720
PILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAV
Sbjct: 661 PILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAV 720
Query: 721 SAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTS 780
SAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTS
Sbjct: 721 SAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTS 780
Query: 781 APSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTG 840
APSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTG
Sbjct: 781 APSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTG 840
Query: 841 PSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQ 900
PSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQ
Sbjct: 841 PSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQ 900
Query: 901 SLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPL 960
SLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPL
Sbjct: 901 SLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPL 960
Query: 961 TTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQL 1020
TTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQL
Sbjct: 961 TTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQL 1020
Query: 1021 EQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGPTA 1073
EQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGPTA
Sbjct: 1021 EQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGPTA 1073
>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
Length = 780
Score = 252 bits (644), Expect = 1e-66
Identities = 256/808 (31%), Positives = 357/808 (44%), Gaps = 158/808 (19%)
Query: 312 TVNNV-NITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNG 370
T+NNV + G+ +PN+ + +AA + G GV S +V SG
Sbjct: 71 TLNNVGDAETPGTVSPNLL--------LDGQLAAAAAAPANGGGVVSARSV---SGALAS 119
Query: 371 TISSSAAVSSVPNAA-----AGMTGGSVSSQQQQP-TVNTSRFRVVKLD-SSSEPFKKGR 423
T++++A + P A AG + G V++ QP T +SRFRV+KLD S EP+++GR
Sbjct: 120 TLAAAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGR 179
Query: 424 WTCTEFYEKENAVPATEGVLINKVVETVKQNP-IEVTSERESTSGSSVSSSVSTLSHYTE 482
WTC E+YE+++ + ++ + + ++ + + T+ER+S G++ S V ++
Sbjct: 180 WTCMEYYERDS-----DSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQG 234
Query: 483 SVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQS 542
+ G E G + + Q ++ QP T Q S G P + +++QS
Sbjct: 235 AHGP-ESGTDSSLTAVSQLPPSEKMSQP-----TPAQPQSFSVGQPQPPPPPVGGAVAQS 288
Query: 543 QISQVQLQSQELSYQQKQGLQPVPLQAT-----MSAATGIQPSPVNVVGVTSALGQQPSI 597
L P P AT M+AA QP G T P+
Sbjct: 289 SAP----------------LPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLP----PTN 328
Query: 598 SSLAQPQLPYSQAAPPVQTPLPGAPPPQQ-LQYGQQQPMVSTQMAPGHVKSVTQNPASEY 656
+LAQP + + PP P GAP QQ Q+ QP Q+ PGH+ V + SEY
Sbjct: 329 VTLAQPAM----SLPPQPGPAVGAPAAQQPQQFAYPQP----QIPPGHLLPVQPSGQSEY 380
Query: 657 VQQQPILQTAMSSGQPSSAGVGAG---TTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPV 713
+QQ S QPSS G A +PV Q ++V AQ GAS QP
Sbjct: 381 LQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNA------SSVGAQLMGASSQP- 433
Query: 714 GQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGII 773
+A A + G Q+A Q +P A Q G P S VPP Q G
Sbjct: 434 SEAMAPRTGPAQGGQVAPC-QPTGVPPATVGGVVQPCLGPAGAGQPQS---VPPPQMG-- 487
Query: 774 HQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVT 833
L VP P V P + PA PS S+S T
Sbjct: 488 ------------------GSGPLSAVPGGPHAVVPGVPNV-----PAAVPAPSVPSVSTT 524
Query: 834 SQVSSTGPSGMPSAPTNLVPPQNIAQ-TPATQNGNLVQSVSQPPLIATNTNLPLAQQIPL 892
S MP+ P L Q ++ TP +++ +++Q V P T++ Q L
Sbjct: 525 SVT-------MPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDL 577
Query: 893 SSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQT-ISGDSGGMSAVSDGSSSSLAASAS 951
S Q Q L Q++D RR +EP LPQ +S + V + SLA
Sbjct: 578 SQFQTQTQPLV----GQVDDTRRKSEP----LPQPPLSLIAENKPVVKPPVADSLANPLQ 629
Query: 952 LFPLK-----VLPLTTPLVDGED-----------------------ESSSGASVVAIDNK 983
L P+ V + P+ ED +S+SG VVAIDNK
Sbjct: 630 LTPMNSLATSVFSIAIPVDGDEDRNPSTAFYQAFHLNTLKESKSLWDSASGGGVVAIDNK 689
Query: 984 IEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQL 1043
IEQAMDLVKSHLMYAVREEVEVLKEQIKEL+E+NS LE+EN LLK+L+S +QL+Q Q
Sbjct: 690 IEQAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSLSSNDQLSQLPTQ- 748
Query: 1044 QTGSPPATTQPQGT-------TQPPAQP 1064
+P +T+Q Q TQPP QP
Sbjct: 749 -QANPGSTSQQQAVIAQPPQPTQPPQQP 775
Score = 114 bits (286), Expect = 4e-25
Identities = 203/725 (28%), Positives = 271/725 (37%), Gaps = 141/725 (19%)
Query: 106 KKKSGFQITSVTPAQISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDL 165
KKKS FQITSVT AQ++ SI+ EDTES DD DES TED+SS EI DVS RATD
Sbjct: 7 KKKSCFQITSVTTAQVATSIT------EDTESLDDPDESRTEDVSS-EIFDVS--RATDY 57
Query: 166 GEPE---RSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHH 222
G E RSSSEETLNN +AETPG VSPN L + A P
Sbjct: 58 GPEEVCERSSSEETLNNVGDAETPGTVSPN-----------LLLDGQLAAAAAAP----- 101
Query: 223 HHQIHHGHHLQHGHHHPSHVAVASASITGGP-PSSPVSRKLSTTGSSDSITPVAPTSAVS 281
+ G + + + +A+ T P P +P +L+ GSS AP
Sbjct: 102 ---ANGGGVVSARSVSGALASTLAAAATSAPAPGAPGGPQLA--GSSAGPVTAAP----- 151
Query: 282 SSGSPASVMTNMRAPSTTGGIGINSVTGTSTVNNVNITAVGSFNPNVTSSML---GNVNI 338
S P + + R G G T + + + SS+L G+
Sbjct: 152 -SQPPTTCSSRFRVIKLDHGSG-------EPYRRGRWTCMEYYERDSDSSVLTRSGDCIR 203
Query: 339 STSNIPSAAGVSVGPGVTSGVNVNILSGM------GNGTISSSAAVSSVPNAAAGMTGGS 392
+S A G G T G V +++ M +GT SS AVS +P
Sbjct: 204 HSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLP---------- 253
Query: 393 VSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVK 452
S + QPT + + F G + + P G V
Sbjct: 254 PSEKMSQPT-----------PAQPQSFSVG--------QPQPPPPPVGG--------AVA 286
Query: 453 QNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPAL 512
Q+ + + +G + + S + G+ PT V Q Q PA+
Sbjct: 287 QSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAV 346
Query: 513 QGVTLQQ-MDFGSTGPQSIPAVSIP-QSISQSQISQVQLQSQELSYQQKQGLQPVPLQAT 570
QQ F PQ P +P Q QS+ Q Q GLQP P A
Sbjct: 347 GAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQ----------QHVAGLQP-PSPAQ 395
Query: 571 MSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYG 630
S +TG SP + GQ S S AQ SQ + + AP Q G
Sbjct: 396 PS-STGAAASPATAATLPVGTGQNAS-SVGAQLMGASSQPSEAM------APRTGPAQGG 447
Query: 631 QQQPMVSTQMAPGHVKSVTQ---NPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVA 687
Q P T + P V V Q PA Q Q + M P SA G V+P
Sbjct: 448 QVAPCQPTGVPPATVGGVVQPCLGPAGA-GQPQSVPPPQMGGSGPLSAVPGGPHAVVP-- 504
Query: 688 QPQGIQLPVQPTAVPAQPAGASVQ-----------PVGQAPAAVSAVPTGSQIANIGQQA 736
+P P AVPA P+ SV P+ Q+ S P S+ ++I Q
Sbjct: 505 -----GVPNVPAAVPA-PSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPV-SRSSSIIQHV 557
Query: 737 NIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSL 796
+P A P T P+ + Q Q G + + S P L + +++
Sbjct: 558 GLPLA---PGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKP 614
Query: 797 LTVPP 801
+ PP
Sbjct: 615 VVKPP 619
Score = 36.6 bits (83), Expect = 0.13
Identities = 95/470 (20%), Positives = 145/470 (30%), Gaps = 131/470 (27%)
Query: 46 TGVGSNATSSEDFPPPSLLQPPPPA---ASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGG 102
+G S+ T+ PP + P PA + S PQPPPP ++Q+ P PG
Sbjct: 240 SGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPF-PGA 298
Query: 103 TQMKKKSGFQITSVTPAQISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRA 162
T P +A S ++ +V+L++
Sbjct: 299 A----------TGPQPMMAAAQPSQPQGAGPGGQTLPP--------------TNVTLAQP 334
Query: 163 TDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHH 222
P+ + P A P Q PQP +P P + + + +L
Sbjct: 335 AMSLPPQPGPA---------VGAPAAQQPQQFAYPQPQIP--PGHLLPVQPSGQSEYLQQ 383
Query: 223 HHQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSS 282
H G PS +S G +SP + G+ + + V + +
Sbjct: 384 H---------VAGLQPPSPAQPSST----GAAASPATAATLPVGTGQNASSVG-AQLMGA 429
Query: 283 SGSPASVMTNMRAPSTTGGIGINSVTGT--STVNNVNITAVGSFNPNVTSSMLGNVNIST 340
S P+ M P+ G + TG +TV V +G
Sbjct: 430 SSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLG------------------ 471
Query: 341 SNIPSAAG--VSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQ 398
P+ AG SV P G LS + G A V VPN A + SV
Sbjct: 472 ---PAGAGQPQSVPPPQMGGSGP--LSAVPGG---PHAVVPGVPNVPAAVPAPSV----- 518
Query: 399 QPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEV 458
P+V+T+ T+ P +
Sbjct: 519 -PSVSTTSV------------------------------------------TMPNVPAPL 535
Query: 459 TSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQ 508
++ +S + VS S S + H + G APT + Q Q Q Q Q
Sbjct: 536 AQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQ 585
>gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens]
Length = 144
Score = 202 bits (513), Expect = 2e-51
Identities = 104/105 (99%), Positives = 104/105 (99%)
Query: 969 DESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLK 1028
D SSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLK
Sbjct: 40 DNSSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLK 99
Query: 1029 TLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGPTA 1073
TLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGPTA
Sbjct: 100 TLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGPTA 144
>gi|37622901 TSC22 domain family, member 3 isoform 2 [Homo sapiens]
Length = 134
Score = 127 bits (319), Expect = 6e-29
Identities = 68/92 (73%), Positives = 77/92 (83%), Gaps = 1/92 (1%)
Query: 969 DESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLK 1028
D S+SGASVVAIDNKIEQAMDLVK+HLMYAVREEVE+LKEQI+EL+EKNSQLE+EN LLK
Sbjct: 39 DNSASGASVVAIDNKIEQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLK 98
Query: 1029 TLASPEQLAQFQAQLQTGSPPATTQPQGTTQP 1060
TLASPEQL +FQ+ L + PA PQ P
Sbjct: 99 TLASPEQLEKFQSCL-SPEEPAPESPQVPEAP 129
>gi|37622903 TSC22 domain family, member 3 isoform 1 [Homo sapiens]
Length = 200
Score = 125 bits (313), Expect = 3e-28
Identities = 67/90 (74%), Positives = 76/90 (84%), Gaps = 1/90 (1%)
Query: 971 SSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTL 1030
S+SGASVVAIDNKIEQAMDLVK+HLMYAVREEVE+LKEQI+EL+EKNSQLE+EN LLKTL
Sbjct: 107 SASGASVVAIDNKIEQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTL 166
Query: 1031 ASPEQLAQFQAQLQTGSPPATTQPQGTTQP 1060
ASPEQL +FQ+ L + PA PQ P
Sbjct: 167 ASPEQLEKFQSCL-SPEEPAPESPQVPEAP 195
>gi|13569901 TSC22 domain family, member 4 [Homo sapiens]
Length = 395
Score = 114 bits (284), Expect = 6e-25
Identities = 101/282 (35%), Positives = 135/282 (47%), Gaps = 21/282 (7%)
Query: 783 SLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQ-QLPAVSSLPSASSIS-------VTS 834
SL +L +AS L P P G+ +QG S + P S P A S + V S
Sbjct: 123 SLDSRLELASLG--LGAPTPPSGL---SQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPS 177
Query: 835 QVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPL-IATNTNLPLAQQIPLS 893
+ + P S+P P ++ T + P L + A+ PLS
Sbjct: 178 KAKAEKPPLSASSPQQRPPEPETGESAGTSRA----ATPLPSLRVEAEAGGSGARTPPLS 233
Query: 894 STQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLF 953
+ L +G+ E + S P + S ++AA
Sbjct: 234 RRKAVDMRLRMELGAPEEMGQVPPLDSRPSSPALYFTHDASLVHKSPDPFGAVAAQKFSL 293
Query: 954 PLKVLPLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKEL 1013
+L ++ L D +D+S SG S+V IDNKIEQAMDLVKSHLM+AVREEVEVLKEQI+EL
Sbjct: 294 AHSMLAISGHL-DSDDDSGSG-SLVGIDNKIEQAMDLVKSHLMFAVREEVEVLKEQIREL 351
Query: 1014 IEKNSQLEQENNLLKTLASPEQLAQFQAQ-LQTGSPPATTQP 1054
E+N+ LEQEN LL+ LASPEQLAQ + + PPA P
Sbjct: 352 AERNAALEQENGLLRALASPEQLAQLPSSGVPRLGPPAPNGP 393
Score = 43.9 bits (102), Expect = 8e-04
Identities = 64/254 (25%), Positives = 94/254 (37%), Gaps = 46/254 (18%)
Query: 391 GSVSSQQQQPTVNTSRFRVVKLDSS-SEPFKKGRWTCTEFYEKENAVPATEGVLINKVVE 449
G+ + P +SRFRVVKL EP+++GRWTC + YE++ + G+L
Sbjct: 56 GTPRNGSPPPGAPSSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLL------ 109
Query: 450 TVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQ 509
E G+S + +L E G +GAPT Q +
Sbjct: 110 -------------EGIRGASGGAGGRSLDSRLELASLG-LGAPTPPSGLSQGPTSWLRPP 155
Query: 510 PALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQI-SQVQLQSQELSYQQKQGLQPVPLQ 568
P S GPQ A S + Q + S+ + + LS Q P P +
Sbjct: 156 PT------------SPGPQ---ARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEP-E 199
Query: 569 ATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQ 628
SA T +P+ + V + G S P L +A GAP +
Sbjct: 200 TGESAGTSRAATPLPSLRVEAEAGG----SGARTPPLSRRKAVDMRLRMELGAPE----E 251
Query: 629 YGQQQPMVSTQMAP 642
GQ P+ S +P
Sbjct: 252 MGQVPPLDSRPSSP 265
>gi|62865625 TSC22 domain family, member 3 isoform 3 [Homo sapiens]
Length = 77
Score = 96.7 bits (239), Expect = 1e-19
Identities = 51/73 (69%), Positives = 59/73 (80%), Gaps = 1/73 (1%)
Query: 988 MDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGS 1047
MDLVK+HLMYAVREEVE+LKEQI+EL+EKNSQLE+EN LLKTLASPEQL +FQ+ L +
Sbjct: 1 MDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCL-SPE 59
Query: 1048 PPATTQPQGTTQP 1060
PA PQ P
Sbjct: 60 EPAPESPQVPEAP 72
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 91.3 bits (225), Expect = 4e-18
Identities = 209/1067 (19%), Positives = 366/1067 (34%), Gaps = 164/1067 (15%)
Query: 5 PESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPPPSLL 64
P +T+A A ++ +A ++ P P G ++ + T V ++ S+ P
Sbjct: 1426 PGTTSAEATSSPTTAEGISIPTSTP--SEGKTPLKSIPVSNTPVANSEASTLSTTPVDSN 1483
Query: 65 QPPPPAASSTSGPQPPPPQSLNLLSQAQ-LQAQPLAPGGTQMKKKSGFQITSVTPAQISA 123
P + + +S P P S+ + + ++ A P T S S TPA S
Sbjct: 1484 SPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTST 1543
Query: 124 SI------SSNNSIAEDTESYDDLDESHTEDLSS---SEILDVSLSRATDLGEPERSSSE 174
+ SS+ + A+ T + L+S S +L VS T P S ++
Sbjct: 1544 PVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQ 1603
Query: 175 ETLNNFQEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQH 234
T + + T S P P L
Sbjct: 1604 VTASTEASSSTTAEGSSMTISTPSEGSPLL------------------------------ 1633
Query: 235 GHHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMR 294
S ++ P +SP + LSTT DS +PV ++ VSSS +PA
Sbjct: 1634 ----------TSIPVSTTPVASPEASTLSTT-PVDSNSPVITSTEVSSSPTPAE------ 1676
Query: 295 APSTTGGIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPG 354
G + T T T +T++ V SS + +ST+ + ++ V+
Sbjct: 1677 --------GTSMPTSTYTEGRTPLTSITVRTTPVASSAIS--TLSTTPVDNSTPVTTSTE 1726
Query: 355 VTSGVNVNILSGMGNGTIS-SSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLD 413
S + + M N T S + ++S+P + + S+ P ++TS +
Sbjct: 1727 ARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATP-IDTSTPVTTSTE 1785
Query: 414 SSSEPFKK-----GRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTS---EREST 465
++S P T +E + P + ++ N T+ P++ S +
Sbjct: 1786 ATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAV 1845
Query: 466 SGSSVSSSVSTLSHYTESVGSGEM-GAPTVVVQQQQQQQQQQQQQPALQG---VTLQQMD 521
S S + ++++ T S GS + P + PA+ T Q+
Sbjct: 1846 SSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVS 1905
Query: 522 F------GSTGPQSI------PAVSIPQSISQSQISQVQLQSQEL--------SYQQKQG 561
GS+ P S P SIP S + S++ S L +Y Q
Sbjct: 1906 SSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASS 1965
Query: 562 LQ----------------PVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQL 605
PL + + T + S + + T P+ +S
Sbjct: 1966 SPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSS 2025
Query: 606 PYSQAAPPVQ--------TPLPGAPPPQQLQYGQQQPMVSTQMAPG--HVKSVTQNPASE 655
P + +Q TPL G P L + +ST V + T+ +S
Sbjct: 2026 PTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSA 2085
Query: 656 YVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQP---------------TA 700
+ + +A S G P + TT PVA P+ L P +
Sbjct: 2086 TAEGSSMTISAPSEGSPLLTSIPLSTT--PVASPEASTLSTTPVDSNSPVITSTEVSSSP 2143
Query: 701 VPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPP 760
+P + ++++P + + + + T ST V S + +P
Sbjct: 2144 IPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPT 2203
Query: 761 SSQ-VVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLP 819
+S+ P T TS P + V+ S++S L+ P V+
Sbjct: 2204 TSEGTSMPTSTPSEGSTPFTSMP-VSTMPVVTSEASTLSATPVDTSTP------VTTSTE 2256
Query: 820 AVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQN-----IAQTPATQNGNLVQS--V 872
A SS +A S+ + S G + + S P + N ++ TP N S
Sbjct: 2257 ATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEA 2316
Query: 873 SQPPLIATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDS 932
S PP A T++P + +T + ++ + + E + + P+ P T +
Sbjct: 2317 SSPPPTAEGTSMPTSTSSE-GNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQA 2375
Query: 933 GGMSAVSDGSSSSLAA-SASLFPLKVLPLTT-PLVDGEDESSSGASV 977
G +D +S + S PL +P++T P+V E + S V
Sbjct: 2376 GSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPV 2422
Score = 85.9 bits (211), Expect = 2e-16
Identities = 173/895 (19%), Positives = 322/895 (35%), Gaps = 95/895 (10%)
Query: 244 VASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTGGIG 303
+ S ++ P +SP + LSTT DS +PV ++ VSSS +PA + + + G
Sbjct: 808 LTSIPVSITPVTSPEASTLSTT-PVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTP 866
Query: 304 INSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNI 363
+ S+ ++T+ + + S P TS+ + N + S+ ++ G S+ P T G
Sbjct: 867 LTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSM-PTSTPGEGSTP 925
Query: 364 LSGMGNGT---------------------ISSSAAVSSVPNAAAG--------------- 387
L+ M + T +++S +S P A G
Sbjct: 926 LTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPL 985
Query: 388 --------MTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPAT 439
+ S +S V+++ ++SS P + E + P T
Sbjct: 986 TSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLT 1045
Query: 440 EGVLINKVVETVKQNPIEVTSEREST------SGSSVSSSVSTLSHYTESVGSGEMGAPT 493
+ +V + + + + T ST SS S++ S T + G +
Sbjct: 1046 RMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTS 1105
Query: 494 VVVQQQ---QQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSI---PQSISQSQISQV 547
V V + + P + + S+ P + SI P S + ++ +
Sbjct: 1106 VPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASM 1165
Query: 548 QLQSQELSYQQKQGLQPVPLQATMSAATGIQ-PSPVNVVGVTSALGQQPSISSLAQPQLP 606
+ + + + L P+ + AT + SP VTS P S +P
Sbjct: 1166 PVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMP 1225
Query: 607 Y-------SQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQ 659
S+A+ +P+ + P P T + + T + S +
Sbjct: 1226 VRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSP---TTAEGTSLPTSTTSEGSTLLTS 1282
Query: 660 QPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAA 719
P+ T ++S + S+ TT + P V + PA+ +
Sbjct: 1283 IPVSTTLVTSPEAST----LLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTP 1338
Query: 720 VSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQT 779
++++P + + + + T ST V S +P +S+ +
Sbjct: 1339 LTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPL 1398
Query: 780 SAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSST 839
++ + V++S++S L+ P V+ G S + A SS +A IS+ + S
Sbjct: 1399 TSIPVSTTPVVSSEASTLSATP----VDTSTPGTTSAE--ATSSPTTAEGISIPTSTPSE 1452
Query: 840 GPSGMPSAPTNLVPPQN-----IAQTPATQNGNLVQS--VSQPPLIATNTNLPLAQQIPL 892
G + + S P + P N ++ TP N +V S VS P A T++ ++
Sbjct: 1453 GKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSE- 1511
Query: 893 SSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAA-SAS 951
ST ++ ++ + E + P++ P T + +DG+S + S
Sbjct: 1512 GSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEG 1571
Query: 952 LFPLKVLPLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIK 1011
PL LP++T LV + ++ S ID+K + S A E I
Sbjct: 1572 STPLTSLPVSTMLVVSSEANT--LSTTPIDSKTQVTASTEASSSTTA-----EGSSMTIS 1624
Query: 1012 ELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPAS 1066
E + L +ASPE + + SP T+ ++ PA+ S
Sbjct: 1625 TPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTS 1679
Score = 77.0 bits (188), Expect = 9e-14
Identities = 202/1067 (18%), Positives = 370/1067 (34%), Gaps = 120/1067 (11%)
Query: 5 PESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPPPSLL 64
P +T+ A ++ ++ + P P G+ +++ + T V S+ S+ P
Sbjct: 1720 PVTTSTEARSSPTTSEGTSMPNSTP--SEGTTPLTSIPVSTTPVLSSEASTLSATPIDTS 1777
Query: 65 QPPPPAASSTSGPQPPPPQSL--NLLSQAQ--LQAQPLAP---GGTQMKKKSGFQITSVT 117
P + +TS P S+ + LS+ L + P++ ++ S + S +
Sbjct: 1778 TPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNS 1837
Query: 118 PAQISASISSNNSIAEDTESYDDLDESHTEDLSSSEI--LDVSLSRATDLGEPERSSSEE 175
P S ++SS+ + AE T + L+S + V+ S L +S
Sbjct: 1838 PVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTP 1897
Query: 176 TLNNFQEAETP-----GAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGH 230
Q + +P ++ + P +P L +P + + +I+
Sbjct: 1898 VTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASS----------EINTLS 1947
Query: 231 HLQHGHHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITPVA--PTSAVSSSGSPAS 288
P V + S P++ + T S+ TP+ P S S AS
Sbjct: 1948 TTLADTRTP----VTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEAS 2003
Query: 289 VMTNMRAPSTTGGIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAG 348
++ P T S G+S+ T++ + P+ ++ L + +ST+ + S+ G
Sbjct: 2004 TLST--TPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEG 2061
Query: 349 --VSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSR 406
+S P + N + T S+ S P+ + + S + S
Sbjct: 2062 NTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEAST 2121
Query: 407 FRVVKLDS----------SSEPF-KKGRWTCTEFYEKE----NAVPATEGVLINKVVETV 451
+DS SS P +G T Y ++P + V+ + + T+
Sbjct: 2122 LSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTL 2181
Query: 452 KQNPIE----VTSERESTSGSSVSSSVSTLSHYTESVGSGEM-GAPTVVVQQQQQQQQQQ 506
P++ VT+ E+ S + S S + T S GS P + +
Sbjct: 2182 STTPVDTSTPVTNSTEARSSPTTSEGTS-MPTSTPSEGSTPFTSMPVSTMPVVTSEASTL 2240
Query: 507 QQQPALQGVTLQQMDFGSTGPQSIPAVSIPQS--------ISQSQISQVQLQSQELSYQQ 558
P + ++ P + SIP S ++ +S + + E+S
Sbjct: 2241 SATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVS--- 2297
Query: 559 KQGLQPVPLQATMSAATGIQPSPVNVVGV-----TSALGQQP-SISSLAQPQLPYSQAAP 612
PV + +T P G TS+ G P + ++ + + +
Sbjct: 2298 TLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETST 2357
Query: 613 PVQTPLPGAPPPQQLQYGQQQPMVS--TQMAPGHVKSVTQNPASEYVQQQPILQTAMSSG 670
TP + P P + T M + S V P++ + S+
Sbjct: 2358 LSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEAST- 2416
Query: 671 QPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIA 730
S+ V T V + + T++P P P+ P VS P S
Sbjct: 2417 -HSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMP--VSTTPVVS--- 2470
Query: 731 NIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQ-VVPPAQTGIIHQGVQTSAPSLPQQLV 789
+ + T ST + S +P +++ +V P T + TS P +
Sbjct: 2471 --SEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVA 2528
Query: 790 IASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPT 849
S+L T P V+ + + S ++ SS SA S+ + S G + + S P
Sbjct: 2529 SPEASTLSTTP-----VDSNSPVVTSTEIS--SSATSAEGTSMPTSTYSEGSTPLRSMPV 2581
Query: 850 NLVP-----PQNIAQTPATQNGNLVQS--VSQPPLIATNTNLPLAQQIPLS--------S 894
+ P ++ TP + + S S P A +T++P++ +S S
Sbjct: 2582 STKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVS 2641
Query: 895 TQFSAQSLAQAIGSQIEDARRAAEPS--LVGLPQTISGDSGGMSAVSDGS--------SS 944
T A S A + + D R S P T G S S + S S+
Sbjct: 2642 TMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVST 2701
Query: 945 SLAASASLFPLKVLPL--TTPLVDGEDESSSGASVVAIDNKIEQAMD 989
+L A++ L P+ +TP+ + SSS + +I D
Sbjct: 2702 TLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSD 2748
Score = 76.6 bits (187), Expect = 1e-13
Identities = 173/828 (20%), Positives = 317/828 (38%), Gaps = 119/828 (14%)
Query: 246 SASITGGPPSS-PVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRA--------- 295
S +T P S+ PV+ ++ S+ SITPV ++ V++S P+S+ T A
Sbjct: 333 STPLTSTPASTMPVA---TSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLS 389
Query: 296 --------------------PSTTGGIGINSVTGTSTVNNVNI-------TAVGSFNPNV 328
STT I ++S T +T + + T++ + P+
Sbjct: 390 EGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSE 449
Query: 329 TSSMLGNVNISTSNIPS--AAGVSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNA-- 384
S+ L ++ +ST+ + S A+ +S P V S V + + +A V+S+P +
Sbjct: 450 GSTPLTSMPVSTTPVASSEASNLSTTP-VDSKTQVTTSTEASSS--PPTAEVNSMPTSTP 506
Query: 385 AAGMTGGSVSSQQQQPTVNT--SRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPA---T 439
+ G T + S P ++ S +D+S+ + + + ++P +
Sbjct: 507 SEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPS 566
Query: 440 EG--VLINKVVETVKQNPIEVTSERESTSGSSVSSS--VSTLSHYTESVGSGE-MGAPTV 494
EG L N V T + V+SE +TS + S+ V+T S + S + E PT
Sbjct: 567 EGSTPLTNMPVST----RLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTS 622
Query: 495 VVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGP--QSIPAVSIPQSISQSQISQVQLQSQ 552
++ L V + ST P + P + ++ S S ++
Sbjct: 623 TYSERGTTITSMSVSTTL--VASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPT 680
Query: 553 ELSYQQKQGLQPVPLQATM---SAATGIQPSPVNV-VGVTSALGQQPSISSLAQPQLPYS 608
+ L +P+ T+ S A+ + +PV+ VT++ S ++ +P S
Sbjct: 681 STYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTS 740
Query: 609 QAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQM--APGHVKSVTQ---NPASEYVQQQPIL 663
+ TPL P + L + +ST H+ + T+ +P + PI
Sbjct: 741 TPSEG-STPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPI- 798
Query: 664 QTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQP---------------TAVPAQPAGA 708
+ S G P + T PV P+ L P + PA+
Sbjct: 799 -STPSEGSPLLTSIPVSIT--PVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSM 855
Query: 709 SVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQ--VVP 766
+ ++++P + + + + T ST V S + +P +S+ +P
Sbjct: 856 PTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMP 915
Query: 767 PAQTGIIHQGVQTSAPSLPQQL--VIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSL 824
+ G +G T S+P V++S++ L+ P V+ A SS
Sbjct: 916 TSTPG---EG-STPLTSMPDSTTPVVSSEARTLSATPVDTSTP------VTTSTEATSSP 965
Query: 825 PSASSISVTSQVSSTGPSGMPSAPTNLVPPQN-----IAQTPATQNGNLVQS--VSQPPL 877
+A S+ + S G + + S P + N ++ TP N L S S PP
Sbjct: 966 TTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPP 1025
Query: 878 IATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSA 937
A T++P + ST + ++ + + E + + P+ P T + S
Sbjct: 1026 TAEGTSMPTSTPSE-GSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSST 1084
Query: 938 VSDGSSSSLAA-SASLFPLKVLPLTTPLVDGEDESSSGASVVAIDNKI 984
+DG+S + S PL +P++T LV + S+ S +D I
Sbjct: 1085 TADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEAST--LSTTPVDTSI 1130
Score = 76.6 bits (187), Expect = 1e-13
Identities = 205/1037 (19%), Positives = 372/1037 (35%), Gaps = 107/1037 (10%)
Query: 7 STAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPPPSLLQP 66
+T+ A+ + + + P P GS +++ + T V S S+ P P
Sbjct: 779 TTSTEASCSPTTTEGTSMPISTP--SEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSP 836
Query: 67 PPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLA--PGGTQMKKKSGFQITSVTPAQISAS 124
+ +S P P S+ + ++ + PL P T + S S TP S
Sbjct: 837 VTTSTEVSSSPTPAEGTSMPTSTYSEGRT-PLTSMPVSTTLVATSAISTLSTTPVDTSTP 895
Query: 125 ISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNFQ-EA 183
++++ + S E + S+ L+ D P SS TL+ +
Sbjct: 896 VTNST----EARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDT 951
Query: 184 ETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHP--SH 241
TP S P + G H + P S+
Sbjct: 952 STPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSN 1011
Query: 242 VAVASASITGGPPSSPVSRKLSTTGSSDSITPVA--PTSAVSSSGSPASVMTNMRAPSTT 299
+ +++ PP + + T+ S+ TP+ P S + S S ++ A ++T
Sbjct: 1012 TPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTST 1071
Query: 300 GGIGINSVTGTSTVNNVNITAVGSFNPNVT----SSMLGNVNISTSNIPS--AAGVSVGP 353
VT S ++ + TA G+ P T S+ L +V +ST + S A+ +S P
Sbjct: 1072 ------PVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTP 1125
Query: 354 -----GVTSGVNVNILSGMGNGTI--SSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNT-- 404
VT+ + GT +S + + P A+ ++ V S + T
Sbjct: 1126 VDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPV 1185
Query: 405 -SRFRVVKLDSSSEPFKKGRWTCT------EFYEKENAVPATEGVLINKVVETVKQNPIE 457
S+ +V +S P T E ++P + + T+ +P++
Sbjct: 1186 DSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVD 1245
Query: 458 ----VTSERESTSGSSVSSSVSTLSHYTESVGSGEMG----APTVVVQQQQQQQQQQQQQ 509
VT+ E TS S ++ ++L T S GS + + T+V +
Sbjct: 1246 TSTPVTTSAE-TSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVD 1304
Query: 510 PALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQA 569
VT ++ T + + S ++ ++ + + + ++ L P+
Sbjct: 1305 TKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDN 1364
Query: 570 TMSAATGIQ--PSPVNVVGVTSALGQQPSISSLAQPQLPYSQ-----------AAPPVQT 616
+ T + SP G TS PS + +P S +A PV T
Sbjct: 1365 STPVTTSTEACSSPTTSEG-TSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDT 1423
Query: 617 PLPGAPPPQQLQYGQQQPMVSTQMAPG-HVKSVTQNPASEYVQQQPILQTAMSSGQPSSA 675
PG + S A G + + T + ++ P+ T +++ + S+
Sbjct: 1424 STPGTTSAEATS--------SPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEAST- 1474
Query: 676 GVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQ 735
TT + P V + PA+ ++ + A++++P + +
Sbjct: 1475 ---LSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEI 1531
Query: 736 ANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLP--QQLVIASQ 793
++ T ST V + Q + P++ QT +G T SLP LV++S+
Sbjct: 1532 NSLSTTPAVTSTPV-TTYSQASSSPTTADGTSMQTSTYSEG-STPLTSLPVSTMLVVSSE 1589
Query: 794 SSLLTVPPQPQGVEPVAQGIVSQQLPA-----VSSLPSASSISVTSQVSSTGPSGMPSAP 848
++ L+ P + A S A S PS S +TS ST P P A
Sbjct: 1590 ANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEAS 1649
Query: 849 TNLVPPQNIAQTPATQNGNLVQS--VSQPPLIATNTNLPLAQ----QIPLSSTQFSAQSL 902
T ++ TP N ++ S VS P A T++P + + PL+S +
Sbjct: 1650 T-------LSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPV 1702
Query: 903 AQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSS-SSLAASASLFPLKVLPL- 960
A + S + + P P T S ++ S+G+S + S PL +P+
Sbjct: 1703 ASSAISTL-----STTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVS 1757
Query: 961 TTPLVDGEDESSSGASV 977
TTP++ E + S +
Sbjct: 1758 TTPVLSSEASTLSATPI 1774
Score = 76.6 bits (187), Expect = 1e-13
Identities = 214/1046 (20%), Positives = 374/1046 (35%), Gaps = 146/1046 (13%)
Query: 5 PESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALN---AAGTGVGSNATSSEDFPPP 61
P +T+ A ++ +A + P P G+ +++ ++ A + + +T+ D P
Sbjct: 954 PVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTP 1013
Query: 62 ----SLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVT 117
+ PPP A TS P P + L++ P T M S S T
Sbjct: 1014 LTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRM--------PVSTTMVASSETSTLSTT 1065
Query: 118 PAQISASI------SSNNSIAEDTESYDDLDESHTEDLSSSEI---LDVSLSRATDLGEP 168
PA S + SS+++ A+ T + L+S + L VS +T P
Sbjct: 1066 PADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTP 1125
Query: 169 ERSSSEETLNNFQEAETPGAVSPNQPHLPQPH----LPHLP-QQNVVINGNAHPHHLHHH 223
+S T + + A + P P L +P +V++ A+
Sbjct: 1126 VDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPV 1185
Query: 224 HQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSS 283
Q + +A +T P S+P R T TPVA + A + S
Sbjct: 1186 DS-----KTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLS 1240
Query: 284 GSPASVMTNMRAPSTTGGIGINSVTGTSTVNNVNITAVGSFNPNVTSS----MLGNVNIS 339
SP T P TT +S T TA G+ P T+S +L ++ +S
Sbjct: 1241 TSPVDTST----PVTTSAETSSSPT----------TAEGTSLPTSTTSEGSTLLTSIPVS 1286
Query: 340 TSNIPSAAGVSV--------GPGVTSG-VNVNILSGMGNGTISSS-----AAVSSVPNAA 385
T+ + S ++ GP VTS V+ + G +S+ ++S+P
Sbjct: 1287 TTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNT 1346
Query: 386 AGMTGGSVSSQQQQPTVN----TSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEG 441
+ ++S P N T+ ++SE +E ++P +
Sbjct: 1347 TLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTT 1406
Query: 442 VLINKVVETVKQNPIEVTSERESTSGSSVSSSVST--LSHYTESVGSGEMGAPTVVVQQQ 499
+++ T+ P++ TS +TS + SS + +S T + G+ ++ V
Sbjct: 1407 PVVSSEASTLSATPVD-TSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNT 1465
Query: 500 QQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQK 559
+ TL S P + + ++ S + ++ + + + + +
Sbjct: 1466 PVANSEAS--------TLSTTPVDSNSP-VVTSTAVSSSPTPAEGTSIAISTPS---EGS 1513
Query: 560 QGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQ---- 615
L +P+ T A+ S +N + T A+ P + P + +Q
Sbjct: 1514 TALTSIPVSTTTVAS-----SEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTY 1568
Query: 616 ----TPLPGAPPPQQLQYGQQQPMVSTQM--APGHVKSVTQNPASEYVQQQPILQTAMSS 669
TPL P L + +ST + V + T+ +S + + + S
Sbjct: 1569 SEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSE 1628
Query: 670 GQPSSAGVGAGTTVIPVAQPQGIQLPVQP----------TAVPAQPAGA-------SVQP 712
G P + TT PVA P+ L P T V + P A S
Sbjct: 1629 GSPLLTSIPVSTT--PVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYT 1686
Query: 713 VGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQ-VVPPAQTG 771
G+ P V T + +A+ + + T ST V S + +P +S+ P T
Sbjct: 1687 EGRTPLTSITVRT-TPVAS-SAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTP 1744
Query: 772 IIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSIS 831
TS P + V++S++S L+ P V+ A SS +A S
Sbjct: 1745 SEGTTPLTSIP-VSTTPVLSSEASTLSATPIDTSTP------VTTSTEATSSPTTAEGTS 1797
Query: 832 VTSQVSSTGPSGMPSAPTNLVPPQN-----IAQTPATQNGNLVQS--VSQPPLIATNTNL 884
+ + S G + + S P + N ++ TP N +V S VS P A T++
Sbjct: 1798 IPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSI 1857
Query: 885 ----PLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSD 940
P L+S S ++A + E + P++ P T +D
Sbjct: 1858 ATSTPSEGSTALTSIPVSTTTVASS-----ETNTLSTTPAVTSTPVTTYAQVSSSPTTAD 1912
Query: 941 GSSSSLAA-SASLFPLKVLPLTTPLV 965
GSS + PL +P++T V
Sbjct: 1913 GSSMPTSTPREGRPPLTSIPVSTTTV 1938
Score = 74.7 bits (182), Expect = 4e-13
Identities = 172/851 (20%), Positives = 307/851 (36%), Gaps = 151/851 (17%)
Query: 246 SASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTGGIGIN 305
+A T P S+P R+ T S S PVA + A + S +PA T P TT
Sbjct: 2971 TAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTST----PVTT------ 3020
Query: 306 SVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTS--NIPSAAGVSVGPGVTSGVNVNI 363
S +S+ T + P+ S+ L ++ +ST+ IP A+ +S P V S
Sbjct: 3021 STEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTP-VDS------ 3073
Query: 364 LSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGR 423
N + +S VSS P A G T +S+ + T T
Sbjct: 3074 -----NSPVVTSTEVSSSPTPAEG-TSMPISTYSEGSTPLT------------------- 3108
Query: 424 WTCTEFYEKENAVPATEGVLINKVVETVKQNPIE----VTSERESTSGSSVSSSVSTLSH 479
VP + + + + T+ P++ VT+ E+ S + S S +
Sbjct: 3109 -----------GVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTS-MPT 3156
Query: 480 YTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSI 539
T S GS + V + + T +T + SIP S
Sbjct: 3157 STPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTST 3216
Query: 540 SQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISS 599
++ PL + + T + S +++ T P +S
Sbjct: 3217 PSEGMT--------------------PLTSVPVSNTPVASSEASILSTTPVDSNTPLTTS 3256
Query: 600 LAQPQLPYSQ--AAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYV 657
P + + P TP G+ P + P+ +T +A +++ PA
Sbjct: 3257 TEASSSPPTAEGTSMPTSTPSEGSTPLTSM------PVSTTTVASSETSTLSTTPAD--- 3307
Query: 658 QQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAP 717
P+ + +S P + GT++ +G + P S PV +
Sbjct: 3308 TSTPVTTYSQASSSPP---IADGTSMPTSTYSEG--------STPLTNMSFSTTPVVSSE 3356
Query: 718 A---AVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIH 774
A + + V T + + + + PT + T +P S +G P + +P + T ++
Sbjct: 3357 ASTLSTTPVDTSTPVTTSTEASLSPTTAE--GTSIPTSSPSEGTTPLAS-MPVSTTPVVS 3413
Query: 775 QGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISV-- 832
V T + + ++L+T + +A+G LP ++ ++ +S+
Sbjct: 3414 SEVNTLSTT------PVDSNTLVTTSTEASSSPTIAEG---TSLPTSTTSEGSTPLSIMP 3464
Query: 833 --TSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQI 890
T+ V+S+ S + + P + P +P + + S P A + PL +
Sbjct: 3465 LSTTPVASSEASTLSTTPVDTSTPVT-TSSPTNSSPTTAEVTSMPTSTAGEGSTPLT-NM 3522
Query: 891 PLSSTQFSAQSLAQAIGSQIEDARR--AAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAA 948
P+S+T A S A + + D+ + P T+ + MS S+GSSS
Sbjct: 3523 PVSTTPV-ASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSS---- 3577
Query: 949 SASLFPLKVLPLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKE 1008
LTT L+ +SS AS + + ++++ + S + EV+
Sbjct: 3578 -----------LTTMLLSSTYVTSSEASTPSTPS-VDRSTPVTTSTQSNSTPTPPEVITL 3625
Query: 1009 QIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGSPPATT--------QPQGTTQP 1060
+ E ++ L ++ E + T +P T+ P+GTT P
Sbjct: 3626 PMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMP 3685
Query: 1061 PAQPASQGSGP 1071
P S+GS P
Sbjct: 3686 IWTP-SEGSTP 3695
Score = 73.6 bits (179), Expect = 1e-12
Identities = 224/1125 (19%), Positives = 374/1125 (33%), Gaps = 213/1125 (18%)
Query: 5 PESTAAAAAAADISARKMAHPAMFPRRGSG---SGSASALNAAGTGVGSNATSSEDFPPP 61
P +T A +++ +A + P PR G S S A + + + +T+ D P
Sbjct: 1897 PVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTP 1956
Query: 62 ----SLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVT 117
S P A TS P P + L+ L + ++ S + + T
Sbjct: 1957 VTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVV--SSEASTLSTTPVDTST 2014
Query: 118 PAQISASISSNNSIAEDTESYDDLDESHTEDLSS---SEILDVSLSRATDLGEPERSSSE 174
PA S SS+ + A T T L+ S L VS T P S ++
Sbjct: 2015 PATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQ 2074
Query: 175 ETLNNFQEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQH 234
T N EA + + + P G L
Sbjct: 2075 VT--NSTEASSSATAEGSSMTISAPS---------------------------EGSPL-- 2103
Query: 235 GHHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPA------- 287
+ S ++ P +SP + LSTT DS +PV ++ VSSS P
Sbjct: 2104 ---------LTSIPLSTTPVASPEASTLSTT-PVDSNSPVITSTEVSSSPIPTEGTSMQT 2153
Query: 288 SVMTNMRAPSTTGGIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAA 347
S ++ R P T+ + +V +S ++ ++ T V + P + ++
Sbjct: 2154 STYSDRRTPLTSMPVS-TTVVASSAISTLSTTPVDTSTP----------------VTNST 2196
Query: 348 GVSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRF 407
P + G ++ + T +S VS++P + + S + V TS
Sbjct: 2197 EARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTST- 2255
Query: 408 RVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEV-TSERESTS 466
+++E T +E ++P + ++ N V T+ P++ T ST
Sbjct: 2256 EATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTE 2315
Query: 467 GSSVSSSVSTLSHYTESVGSGEMGA---PTVVVQQQQQQQQQQQQQPALQGVTLQQMDFG 523
SS + S T + G P + PA +
Sbjct: 2316 ASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQA 2375
Query: 524 STGPQSIPAVSIPQS--------ISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAAT 575
+ P + S+P S ++ +S + + S E S PV ++ +T
Sbjct: 2376 GSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEAS---THSTTPVDTSTPVTTST 2432
Query: 576 GIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPM 635
SP G T +P +PP + P+
Sbjct: 2433 EASSSPTTAEG-----------------------------TSIPTSPPSEGTTPLASMPV 2463
Query: 636 VSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQG---- 691
+T + +++ P P+ + +S P++A V+P++
Sbjct: 2464 STTPVVSSEAGTLSTTPVDT---STPMTTSTEASSSPTTAE----DIVVPISTASEGSTL 2516
Query: 692 -IQLPVQPTAVPAQPAGA-SVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQV 749
+PV T V + A S PV S V T ++I++ +A T +
Sbjct: 2517 LTSIPVSTTPVASPEASTLSTTPVDSN----SPVVTSTEISS--------SATSAEGTSM 2564
Query: 750 PPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVP-----PQPQ 804
P S +G+ P S P + L + S+L T P P
Sbjct: 2565 PTSTYSEGSTPLR-----------------SMPVSTKPLASSEASTLSTTPVDTSIPVTT 2607
Query: 805 GVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQ 864
E + ++ S PS S S+TS + ST P A T P + T
Sbjct: 2608 STETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTS 2667
Query: 865 NGNLVQSVSQPPLIATNTNLPLA----QQIPLSSTQFSAQSLAQAIGSQIEDA------- 913
G S P A +++P + + PL++ S LA + S +
Sbjct: 2668 TGT-----SSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTP 2722
Query: 914 -RRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPLTTPLVDGEDESS 972
+AE S P T G S +S SDGS+ PLT+ LV +S
Sbjct: 2723 VTTSAEAS--SSPTTAEGTSMRISTPSDGST---------------PLTSILVSTLPVAS 2765
Query: 973 SGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLAS 1032
S AS V+ ++ ++ + S + EV E ++ L +AS
Sbjct: 2766 SEASTVS-TTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVAS 2824
Query: 1033 PEQLAQFQAQLQTGSPPATTQPQGTTQP--------PAQPASQGS 1069
E + T S P TT + ++ P P AS+GS
Sbjct: 2825 SEAGTLSTTPVDT-STPVTTSTKASSSPTTAEGIVVPISTASEGS 2868
Score = 73.6 bits (179), Expect = 1e-12
Identities = 201/1061 (18%), Positives = 361/1061 (34%), Gaps = 125/1061 (11%)
Query: 5 PESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPPPSLL 64
P ST A++ + P S GS+S A GT + + S P S+L
Sbjct: 2875 PVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSIL 2934
Query: 65 QPPPPAASSTSGPQPPPPQSLN--LLSQAQLQAQPLAPGGTQMK-KKSGFQITSVTPAQI 121
P A S + P + + A+ + P GT M G + T +T
Sbjct: 2935 VSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLT---- 2990
Query: 122 SASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEET--LNN 179
S S+S+ + + + + +++S S + A G P + SE + L +
Sbjct: 2991 SMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTS 3050
Query: 180 FQEAETPGAVSPNQPHLPQPHLPHLP-QQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHH 238
+ TP A+ P + P + ++ + P G + +
Sbjct: 3051 IPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTP---------AEGTSMPISTYS 3101
Query: 239 PSHVAVASASITGGPPSSPVSRKLSTTGSSDSITPVA-----------------PTSAVS 281
+ ++ P +S LSTT D+ TPV PTS S
Sbjct: 3102 EGSTPLTGVPVSTTPVTSSAISTLSTT-PVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPS 3160
Query: 282 SSGSPASVM---------------------------TNMRAPSTTGGIGINSVTGTSTVN 314
+P + M T+ A S+T G + T T +
Sbjct: 3161 EGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEG 3220
Query: 315 NVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTIS- 373
+T+V N V SS +ST+ + S ++ +S + M T S
Sbjct: 3221 MTPLTSVPVSNTPVASSEAS--ILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSE 3278
Query: 374 SSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKE 433
S ++S+P + + S+ P ++ SSS P G T Y E
Sbjct: 3279 GSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTY-SE 3337
Query: 434 NAVPATE-----GVLINKVVETVKQNPIE----VTSERES----TSGSSVSSSVSTLSHY 480
+ P T +++ T+ P++ VT+ E+ T+ S S+ S
Sbjct: 3338 GSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEG 3397
Query: 481 TESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS 540
T + S + VV + P + S+ P S+P S +
Sbjct: 3398 TTPLASMPVSTTPVV----SSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTT 3453
Query: 541 ---QSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSI 597
+ +S + L + ++ + L P+ + T SP N T+ + P+
Sbjct: 3454 SEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTS---SPTNSSPTTAEVTSMPT- 3509
Query: 598 SSLAQPQLPYSQAAPPVQTPLPGA-------PPPQQLQYGQQQPMVSTQMAPGHVKSVTQ 650
S+ + P + P TP+ + P + S+ A V ++
Sbjct: 3510 STAGEGSTPLTN-MPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRM 3568
Query: 651 NPASEYVQQQPIL------QTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQ 704
+ SE + T+ + PS+ V T V Q P + +P
Sbjct: 3569 STPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMS 3628
Query: 705 PAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQP---STQVPPS-VIQQGAPP 760
P+ P + ++V I+ G + +P P STQV S V +G
Sbjct: 3629 TPSEVSTPLTIMPVSTTSV----TISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTM 3684
Query: 761 SSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPA 820
T + V T+ + + + S S++T P E ++
Sbjct: 3685 PIWTPSEGSTPLTTMPVSTTRVTSSEGSTL-STPSVVTSTPVTTSTEAISSSATLDSTTM 3743
Query: 821 VSSLP-SASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIA 879
S+P S++ T VS+T + P + T +P + + T + + S P +
Sbjct: 3744 SVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTAS----EGSSSPTTLE 3799
Query: 880 TNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVS 939
T +P++ S+ + ++ S E + + P P S +G S +
Sbjct: 3800 GTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPA 3859
Query: 940 DGSSSSLAASASLFPLKVLPLTTPLVDGE-DESSSGASVVA 979
+ ++ ++ ++ + PLTT LV S GAS+ +
Sbjct: 3860 EVTTIRISITSE----RSTPLTTLLVSTTLPTSFPGASIAS 3896
Score = 73.2 bits (178), Expect = 1e-12
Identities = 193/932 (20%), Positives = 317/932 (34%), Gaps = 151/932 (16%)
Query: 8 TAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPPPSLLQP- 66
T + A + +A + P P G +++ + T V S+ S P P
Sbjct: 3196 TTSTEATSSTTAEGTSIPTSTP--SEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPL 3253
Query: 67 --------PPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKS----GFQIT 114
PP A TS P P + L+ + +A T + +T
Sbjct: 3254 TTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVT 3313
Query: 115 SVTPAQISASISSNNSIAEDTESYDDLDESH----TEDLSSSEILDVSLSRATDLGEPER 170
+ + A S I+ S+ T S ++ T + SSE +S + D P
Sbjct: 3314 TYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTT-PVDTSTPVT 3372
Query: 171 SSSEETLN-NFQEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHG 229
+S+E +L+ E + SP++ P +P
Sbjct: 3373 TSTEASLSPTTAEGTSIPTSSPSEGTTPLASMP--------------------------- 3405
Query: 230 HHLQHGHHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITPVA------PTSAVSSS 283
S V S+ + + S L TT + S +P PTS S
Sbjct: 3406 ---------VSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEG 3456
Query: 284 GSPASVMTNMRAPSTTGGIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNI 343
+P S+M P +S + ++ T V + P TSS T++
Sbjct: 3457 STPLSIMPLSTTP-----------VASSEASTLSTTPVDTSTPVTTSS-------PTNSS 3498
Query: 344 PSAAGVSVGPGVTSGVNVNILSGMGNGTI----SSSAAVSSVPNAAAGMTGGSVSSQQQQ 399
P+ A V+ P T+G L+ M T S ++ +S+ P + S +
Sbjct: 3499 PTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSP 3558
Query: 400 PTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQN----- 454
T+ + R+ S + T E + P+T V + V T Q+
Sbjct: 3559 ATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPT 3618
Query: 455 PIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMG-APTVVVQQQQQ---QQQQQQQQP 510
P EV + ST S VS+ ++ + T SV E G A T+ V Q
Sbjct: 3619 PPEVITLPMSTP-SEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPV 3677
Query: 511 ALQGVTLQQMDFGSTGPQSIPAVSIPQS---ISQSQISQVQLQSQELSYQQKQGLQPVPL 567
+G T M + S P ++P S ++ S+ S + S S + +
Sbjct: 3678 TPEGTT---MPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISS 3734
Query: 568 QATMSAATGI--QPSPVNVVGVTSALGQQP--SISSLAQPQLPYSQAAPPVQTPLPGAPP 623
AT+ + T P ++ +G T + P + P +P + + T G+
Sbjct: 3735 SATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSS 3794
Query: 624 PQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTV 683
P L+ PM +T + +V +P S MS + S+ G T
Sbjct: 3795 PTTLEGTTTMPMSTTSERSTLLTTVLISPIS-----------VMSPSEASTLSTPPGDTS 3843
Query: 684 IPV---AQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPT 740
P+ + +P + T + P+ + + +PT A+I + T
Sbjct: 3844 TPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTT-LPTSFPGASIASTPPLDT 3902
Query: 741 AVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPS----LPQQLVIASQSSL 796
ST PS P +P A T + + S P +P V +S + +
Sbjct: 3903 -----STTFTPSTDTASTP----TIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADV 3953
Query: 797 LTVPPQPQGVEPVAQGIVSQQLPAVSSL--PSASSISVTSQVSSTG----PSGMPSAPTN 850
P G VS + + L PS SS S T+ S+T P+ +AP
Sbjct: 3954 F----------PATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLT 4003
Query: 851 LVPPQNIAQTPATQNGNLVQSVSQPPLIATNT 882
V TP T + S S L AT+T
Sbjct: 4004 YVTMSTAPSTPRTTSRGCTTSAS--TLSATST 4033
Score = 72.8 bits (177), Expect = 2e-12
Identities = 218/1104 (19%), Positives = 395/1104 (35%), Gaps = 180/1104 (16%)
Query: 7 STAAAAAAADISARKMAHPAM--FPRRGSGSGSASALNAAGTGVGSNA---TSSEDFPPP 61
ST A ++ IS P + P + S A + T V SN+ TS+E
Sbjct: 1613 STTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTE----- 1667
Query: 62 SLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQI 121
+ P A TS P + L+ ++ P+A + + S + + TP
Sbjct: 1668 --VSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVA--SSAISTLSTTPVDNSTPVTT 1723
Query: 122 SASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNFQ 181
S S+ + +E T + T L+S + VS + P SS TL+
Sbjct: 1724 STEARSSPTTSEGTSMPNSTPSEGTTPLTS---IPVSTT-------PVLSSEASTLSATP 1773
Query: 182 -EAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPS 240
+ TP S P G + P L G +
Sbjct: 1774 IDTSTPVTTSTEATSSP-----------TTAEGTSIPTST-----------LSEGMTPLT 1811
Query: 241 HVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTG 300
V+ + S+ LSTT DS +PV ++AVSSS +PA + + + G
Sbjct: 1812 STPVSHTLVANSEAST-----LSTT-PVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEG 1865
Query: 301 GIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVN 360
+ S+ ++T + T S P VTS+ + S+ P+ A S P T
Sbjct: 1866 STALTSIPVSTTTVASSETNTLSTTPAVTSTPV-TTYAQVSSSPTTADGSSMPTSTPREG 1924
Query: 361 VNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEP-- 418
L+ + T + +++ + + T V++ Q + T+ D +S P
Sbjct: 1925 RPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTT------ADGTSMPTP 1978
Query: 419 -FKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEV-TSERESTSGSS------- 469
+ +G T ++P + ++++ T+ P++ T ST GSS
Sbjct: 1979 AYSEGSTPLT-------SMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGG 2031
Query: 470 VSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQS 529
S ST S T + +G + T+VV + Q + +T S
Sbjct: 2032 TSIQTSTPSERTTPL-AGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGS 2090
Query: 530 IPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQ--PVPLQATMSAATGIQPSPVNVVGV 587
+S P S ++ + L + ++ + L PV + + +T + SP+ G
Sbjct: 2091 SMTISAP-SEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGT 2149
Query: 588 TSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKS 647
+ YS P+ + P+ +T +A + +
Sbjct: 2150 SMQTS-------------TYSDRRTPLTS----------------MPVSTTVVASSAIST 2180
Query: 648 VTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAG 707
++ P P+ + + P+++ GT+ +P + P P V P
Sbjct: 2181 LSTTPVD---TSTPVTNSTEARSSPTTS---EGTS-MPTSTPSEGSTPFTSMPVSTMPV- 2232
Query: 708 ASVQPVGQAPAAVSAVP--TGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVV 765
V + +SA P T + + + + PT + T +P S + +G P + +
Sbjct: 2233 -----VTSEASTLSATPVDTSTPVTTSTEATSSPTTAE--GTSIPTSTLSEGTTPLTS-I 2284
Query: 766 PPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLP 825
P + T + + V T + + + S+ + PP P A+G +S+P
Sbjct: 2285 PVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPP------PTAEG---------TSMP 2329
Query: 826 SASSISVTSQVSSTGPSGMPSAPTNLV--PPQNIAQTPATQNGNLV--QSVSQPPLIATN 881
++ TS +T + MP + T + ++ TPA + + P A +
Sbjct: 2330 TS-----TSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADD 2384
Query: 882 TNLPLAQ----QIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSA 937
T++P + PL+S S + + E + + P P T S ++
Sbjct: 2385 TSMPTSTYSEGSTPLTSVPVSTMPVVSS-----EASTHSTTPVDTSTPVTTSTEASSSPT 2439
Query: 938 VSDGSS-SSLAASASLFPLKVLPL-TTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHL 995
++G+S + S PL +P+ TTP+V E + S ++ + + S
Sbjct: 2440 TAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLS-------TTPVDTSTPMTTSTE 2492
Query: 996 MYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGSPPAT---- 1051
+ E + I E ++ L +ASPE + + SP T
Sbjct: 2493 ASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEI 2552
Query: 1052 ----TQPQGTTQPPAQPASQGSGP 1071
T +GT+ P S+GS P
Sbjct: 2553 SSSATSAEGTSM-PTSTYSEGSTP 2575
Score = 70.1 bits (170), Expect = 1e-11
Identities = 161/760 (21%), Positives = 279/760 (36%), Gaps = 98/760 (12%)
Query: 246 SASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPAS----VMTNMRAPST-TG 300
+A +T P S+P T + TPVA + A + S +P V T+ +A S+ T
Sbjct: 2794 TAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTT 2853
Query: 301 GIGINSVTGTSTVNNVNITAVGSFNPNVTS---SMLGNVNISTS-NIPSAAGVSVGPGVT 356
GI T++ + +T++ V S S L + TS + ++ S P
Sbjct: 2854 AEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTA 2913
Query: 357 SGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSS 416
G ++ I + T +S VS+VP A GS +S V+T ++SS
Sbjct: 2914 EGTSMPISTPSEVSTPLTSILVSTVPVA------GSEASTLSTTPVDTRTPVTTSAEASS 2967
Query: 417 EPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVST 476
P + E P T + V + + + + T ST V++S
Sbjct: 2968 SPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTST---PVTTSTEA 3024
Query: 477 LSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIP 536
S T + G+G + + + P ST P +IP S
Sbjct: 3025 SSSPTTAEGTG------IPISTPSEGSTPLTSIPV------------STTPVAIPEASTL 3066
Query: 537 QSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSA----LG 592
+ S V ++ S +P+ +T + PV+ VTS+ L
Sbjct: 3067 STTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLS 3126
Query: 593 QQPSISSLAQPQLPYSQAAP--------PVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGH 644
P +S + ++P P TP G+ P L Y P+ + +
Sbjct: 3127 TTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTP---LTY---MPVSTMLVVSSE 3180
Query: 645 VKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQ 704
+++ P T +++ +++ A T IP + P P+ T+VP
Sbjct: 3181 DSTLSATPVD--------TSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPL--TSVP-- 3228
Query: 705 PAGASVQPVGQAPAAV-SAVPTGSQ---IANIGQQANIPTAVQQPSTQVPPSVIQQGAPP 760
S PV + A++ S P S + ++ PTA T +P S +G+ P
Sbjct: 3229 ---VSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTA---EGTSMPTSTPSEGSTP 3282
Query: 761 SSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGI-VSQQLP 819
+ + P T + ++ + P A S+ +T Q P+A G +
Sbjct: 3283 LTSM--PVSTTTVASSETSTLSTTP-----ADTSTPVTTYSQASSSPPIADGTSMPTSTY 3335
Query: 820 AVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIA 879
+ S P + T+ V S+ S + + P + P T A+ + + S P
Sbjct: 3336 SEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVT-TSTEASLSPTTAEGTSIPTSSP 3394
Query: 880 TNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTIS-GDSGGMSAV 938
+ PLA +P+S+T + + + ++ + TI+ G S S
Sbjct: 3395 SEGTTPLA-SMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTT 3453
Query: 939 SDGSSSSLAASASLFPLKVLPL-TTPLVDGEDESSSGASV 977
S+GS+ PL ++PL TTP+ E + S V
Sbjct: 3454 SEGST----------PLSIMPLSTTPVASSEASTLSTTPV 3483
Score = 67.4 bits (163), Expect = 7e-11
Identities = 150/772 (19%), Positives = 295/772 (38%), Gaps = 88/772 (11%)
Query: 246 SASITGGPPSSP--VSRKLSTTGSS--DSITPVAPTSAVSSSGSPASVMTNMRAPSTTGG 301
S +T P S+ VS + STT ++ DS T V +S SSS + A + + + G
Sbjct: 569 STPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERG 628
Query: 302 IGINSVTGTSTV------NNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGV 355
I S++ ++T+ + ++ T V S P TS+ +TS+ +A G S+
Sbjct: 629 TTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTE------ATSSSTTAEGTSMPTST 682
Query: 356 TSGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSS 415
+ + + S N T+ +S+ S++ + +S + + T+ D +
Sbjct: 683 YTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTA-------DGA 735
Query: 416 SEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSV- 474
S P T +E ++P ++ +L + T+ P++ ++ +++ +S S +
Sbjct: 736 SMPTS----TPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTT 791
Query: 475 --STLSHYTESVGSGEM-GAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIP 531
+++ T S GS + P + + P + S+ P
Sbjct: 792 EGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAE 851
Query: 532 AVSIPQS--------ISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVN 583
S+P S ++ +S + + +S PV ++ +T + SP
Sbjct: 852 GTSMPTSTYSEGRTPLTSMPVSTTLVATSAIS---TLSTTPVDTSTPVTNSTEARSSPTT 908
Query: 584 VVGV---TSALGQ-QPSISSLAQPQLPY--SQAAPPVQTPLPGAPPPQQLQYGQQQPMVS 637
G TS G+ ++S+ P S+A TP+ + P P
Sbjct: 909 SEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSP--- 965
Query: 638 TQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAG---VGAGTTVIPVAQPQGIQL 694
T + + T + + + P+ T +++ + S+ V + T + +
Sbjct: 966 TTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPP 1025
Query: 695 PVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVI 754
+ T++P P+ + P + + V + A+ T V S S
Sbjct: 1026 TAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTT 1085
Query: 755 QQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIV 814
G + T + TS P + +LV++S++S L+ P + V
Sbjct: 1086 ADGTSMPTSTYSEGSTPL------TSVP-VSTRLVVSSEASTLSTTPVDTSIP------V 1132
Query: 815 SQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAP--TNLV---PPQNIAQTPATQNGNLV 869
+ A SS +A S+ + S G + + S P T LV ++ TP +
Sbjct: 1133 TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVA 1192
Query: 870 QS--VSQPPLIATNTNLPLA----QQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVG 923
S S PP A T++P + + PL+S +A + S + + P
Sbjct: 1193 TSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTL-----STSPVDTS 1247
Query: 924 LPQTISGDSGGMSAVSDGSS---SSLAASASLFPLKVLPLTTPLVDGEDESS 972
P T S ++ ++G+S S+ + ++L L +P++T LV + S+
Sbjct: 1248 TPVTTSAETSSSPTTAEGTSLPTSTTSEGSTL--LTSIPVSTTLVTSPEAST 1297
Score = 64.7 bits (156), Expect = 4e-10
Identities = 109/544 (20%), Positives = 199/544 (36%), Gaps = 70/544 (12%)
Query: 448 VETVKQNPIEVTSERESTSGSSV---SSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQ 504
V + + P E + ESTS S+ SS+ T S T M P+
Sbjct: 105 VSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFV 164
Query: 505 QQQQQPALQGVT--LQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGL 562
P+ + T ++D + S A S P + + I + + + L
Sbjct: 165 STAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPK------STNSEGSTPL 218
Query: 563 QPVP---LQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLP 619
+P ++ S A + +PV + + Q S + A+ + A TPL
Sbjct: 219 TSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLT 278
Query: 620 GAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGA 679
P L + +ST A ++ +T AS SS
Sbjct: 279 RMPLSVMLVVSSEASTLSTTPAATNIPVITSTEAS------------------SSPTTAE 320
Query: 680 GTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIP 739
GT++ +G P+ T P S + +++ V T + + + +++P
Sbjct: 321 GTSIPTSTYTEG-STPLTSTPASTMPVATS----EMSTLSITPVDTSTLVTTSTEPSSLP 375
Query: 740 TAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTV 799
T + +T + S + +G+ P + + P T ++ ++ ++P + S++ + T
Sbjct: 376 TTAE--ATSMLTSTLSEGSTPLTNM--PVSTILVASSEASTTSTIP----VDSKTFVTTA 427
Query: 800 PPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQ 859
E + ++ +S PS S +TS ST P A N++
Sbjct: 428 S------EASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEA-------SNLST 474
Query: 860 TPA---TQNGNLVQSVSQPPLIATN---TNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDA 913
TP TQ ++ S PP N T+ P PL+S S +A + S +
Sbjct: 475 TPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTL--- 531
Query: 914 RRAAEPSLVGLPQTISGDSGGMSAVSDGSS-SSLAASASLFPLKVLPLTTPLVDGEDESS 972
+ P P T S ++ S +G+S + S PL +P++T LV + S+
Sbjct: 532 --STTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEAST 589
Query: 973 SGAS 976
+ +
Sbjct: 590 TSTT 593
Score = 61.6 bits (148), Expect = 4e-09
Identities = 186/987 (18%), Positives = 348/987 (35%), Gaps = 86/987 (8%)
Query: 7 STAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPPPSLLQP 66
ST A++ + + P S S+S A GTG+ + S P S+
Sbjct: 2995 STMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVS 3054
Query: 67 PPPAASSTSGPQPPPPQSLN--LLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQISAS 124
P A + P N +++ ++ + P GT M S + S + S
Sbjct: 3055 TTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPI-STYSEGSTPLTGVPVS 3113
Query: 125 ISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSE-ETLNNFQEA 183
+ S A T S +D S S+ + S T + P + SE T +
Sbjct: 3114 TTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSM--PTSTPSEGSTPLTYMPV 3171
Query: 184 ETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPSHVA 243
T VS L + + G +
Sbjct: 3172 STMLVVSSEDSTLSATPVDTSTPVTTSTEATSST--------TAEGTSIPTSTPSEGMTP 3223
Query: 244 VASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTT---G 300
+ S ++ P +S + LSTT DS TP+ TS +SS P + T+M P++T G
Sbjct: 3224 LTSVPVSNTPVASSEASILSTT-PVDSNTPLT-TSTEASSSPPTAEGTSM--PTSTPSEG 3279
Query: 301 GIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVN 360
+ S+ ++T + T+ S P TS+ + + ++S+ P A G S+ P T
Sbjct: 3280 STPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSM-PTSTYSEG 3338
Query: 361 VNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFK 420
L+ M + S++ VSS A+ ++ V + T + + +S P
Sbjct: 3339 STPLTNM---SFSTTPVVSS---EASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTS 3392
Query: 421 KGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIE----VTSERESTSGSSVSSSVST 476
T ++P + +++ V T+ P++ VT+ E++S +++ S
Sbjct: 3393 SPSEGTTPL----ASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTS- 3447
Query: 477 LSHYTESVGSGEMG-APTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSI 535
L T S GS + P + P + ++ P + S+
Sbjct: 3448 LPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSM 3507
Query: 536 PQSIS---QSQISQVQLQSQELSYQQKQGLQPVPLQAT--MSAATGIQPSPVNVVGVTSA 590
P S + + ++ + + + ++ + L P+ + +++++ SP + T
Sbjct: 3508 PTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMR 3567
Query: 591 LGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQ 650
+ SS L S + P P + ++ P V ++
Sbjct: 3568 MSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPM 3627
Query: 651 NPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASV 710
+ SE I+ + +S S AG + +PV + Q ++ P P G ++
Sbjct: 3628 STPSEVSTPLTIMPVSTTSVTISEAGT---ASTLPVDTSTPVITSTQVSSSPVTPEGTTM 3684
Query: 711 QPV-----GQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVV 765
P+ G P V T ++ G + P+ V I A S
Sbjct: 3685 -PIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDS--- 3740
Query: 766 PPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLP 825
T + S+P ++ + L++ P + E P++ S+
Sbjct: 3741 ------------TTMSVSMPMEISTLGTTILVSTTPVTRFPE--------SSTPSIPSVY 3780
Query: 826 SASSISVTSQVSS--TGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIAT--- 880
++ S++ S+ SS T G + P + ++ T + V S S+ ++T
Sbjct: 3781 TSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPG 3840
Query: 881 NTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLV---GLPQTISGDSGGMSA 937
+T+ PL S FS + I I R +L+ LP + G S +
Sbjct: 3841 DTSTPLLTSTKAGS--FSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTP 3898
Query: 938 VSDGSSSSLAASASLFPLKVLPLTTPL 964
D +S++ S +P+ T +
Sbjct: 3899 PLD-TSTTFTPSTDTASTPTIPVATTI 3924
Score = 58.5 bits (140), Expect = 3e-08
Identities = 152/795 (19%), Positives = 279/795 (35%), Gaps = 116/795 (14%)
Query: 263 STTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTGGIGINSVTGTST----VNNVNI 318
ST SS TP + T S++ ++ +T+M A ST ++T +T V I
Sbjct: 191 STQASSSPTTPESTTIPKSTNSEGSTPLTSMPA-STMKVASSEAITLLTTPVEISTPVTI 249
Query: 319 TAVGSFNPN----------------------------VTSSMLGNVNI--STSNIP--SA 346
+A S +P V SS ++ + +NIP ++
Sbjct: 250 SAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITS 309
Query: 347 AGVSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSR 406
S P G ++ + T +S S++P A + M+ S++ V TS
Sbjct: 310 TEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTST 369
Query: 407 FRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIE----VTSER 462
L +++E T +E +P + ++ + T P++ VT+
Sbjct: 370 -EPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTAS 428
Query: 463 ESTSGSSVSSSVSTLSHYTESVGSGEM-GAPTVVVQQQQQQQQQQQQQPALQGVTLQQMD 521
E++S + + S ++ T S GS + P + P +
Sbjct: 429 EASSSPTTAEDTS-IATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTST 487
Query: 522 FGSTGPQSIPAVSIPQSI---SQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQ 578
S+ P + S+P S + ++ + + + ++ + L P+ +
Sbjct: 488 EASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTS-------- 539
Query: 579 PSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVST 638
+PV S+ P +S+ P S+ + TPL P +L + ST
Sbjct: 540 -TPVTTSSEASSSSTTPEGTSI--PTSTPSEGS----TPLTNMPVSTRLVVSSEASTTST 592
Query: 639 QMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIP-------VAQPQG 691
A + T + AS TA + P+S GTT+ VA +
Sbjct: 593 TPADSNTFVTTSSEASS------SSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEA 646
Query: 692 IQLPVQP---------------TAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQA 736
L P ++ A+ + ++++P + + + +
Sbjct: 647 STLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEAS 706
Query: 737 NIPTAVQQPSTQVPPSVIQQGAPPSSQ-VVPPAQTGIIHQGVQTSAPSLPQQLVIASQSS 795
+ T ST V S +P ++ P T TS P + + L+ +S++S
Sbjct: 707 TLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMP-VSKTLLTSSEAS 765
Query: 796 LLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVP-- 853
L+ P ++ A S + S+ S G + S P ++ P
Sbjct: 766 TLSTTPLDTSTH------ITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVT 819
Query: 854 ---PQNIAQTPATQNGNLVQS--VSQPPLIATNTNLPLAQ----QIPLSSTQFSAQSLAQ 904
++ TP N + S VS P A T++P + + PL+S S +A
Sbjct: 820 SPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVAT 879
Query: 905 AIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAA-SASLFPLKVLP-LTT 962
+ S + + P P T S ++ S+G+S + PL +P TT
Sbjct: 880 SAISTL-----STTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTT 934
Query: 963 PLVDGEDESSSGASV 977
P+V E + S V
Sbjct: 935 PVVSSEARTLSATPV 949
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 88.2 bits (217), Expect = 4e-17
Identities = 210/1003 (20%), Positives = 347/1003 (34%), Gaps = 126/1003 (12%)
Query: 32 GSGSGSASALNAAGTGVGSNATSSEDFPPPSLLQPPPPAASSTSGPQPPPPQSLNLLSQA 91
GSG +AL + T + SS + L ++ ST P P S + +S
Sbjct: 961 GSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTG 1020
Query: 92 QLQAQPLAPGGTQMKKKSGFQITSVTPAQISASISSNNSIAEDTESYDDLDESHTEDLSS 151
P+ T +S +T + P +S S+ +S H L
Sbjct: 1021 HTTPLPV----TDTSSESTGHVTPL-PVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPV 1075
Query: 152 SEILDVSLSRATDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPHLPQQNVVI 211
+ + S T L + SS+ +VS H LP +
Sbjct: 1076 TSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTG-------HTTPLPVTDTSS 1128
Query: 212 NGNAHPHHLHHHHQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPVSRKLS-TTGSSDS 270
H L + + GH P HV AS++ TG PV+ S +TG +
Sbjct: 1129 ASTGHATSL----PVTDTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTP 1184
Query: 271 ITPVAPTSAVSSSGSPASVMTNMRAPSTTGGIGINSVTGTSTVNNVNITAVGSFNPNVTS 330
+ +P+SA S+G ++ + ++TG VT S+V+ + T++ P+ S
Sbjct: 1185 LPVTSPSSA--STGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAAS 1242
Query: 331 SMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTG 390
+ T+ +P S G + + V S + G + S+ + +T
Sbjct: 1243 TG------HTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTP 1296
Query: 391 GSVSSQQQQPTVNTSRFRVVKLDSSSE------PFKKGRWTCTEFYEKENAVPATEGVLI 444
V+S T + + V L S+S P T +P T+
Sbjct: 1297 LHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSAST---GDTTPLPVTDA--- 1350
Query: 445 NKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYT---------ESVGSGEMGAPTVV 495
V T P+ VT +++G + V++LS + S S G T +
Sbjct: 1351 -SSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPL 1409
Query: 496 VQQQQQQQQQQQQQP-ALQGVTLQQMDFGSTGPQSIPAVS---------IPQSISQSQIS 545
+ P + + D ++ P +IP+ + + + S S
Sbjct: 1410 LVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQ 1469
Query: 546 QVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSA------------LGQ 593
L + S P+P+ +T SA+TG +P++V +SA L
Sbjct: 1470 ATSLLVTDTSSVSTGDTTPLPVTSTSSASTG-HVTPLHVTSPSSASTGHATPLPVTSLSS 1528
Query: 594 QPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPA 653
+ ++ P S A+ TPLP + G P+ T + T P
Sbjct: 1529 ASTGDTMPLPVTSPSSASTGDTTPLP-VTDASSVSTGHTTPLPVTSPSSASTGHTTPLPV 1587
Query: 654 SEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQ----GIQLPVQPTAVPAQPAGAS 709
++ T + PSSA G TT +PV G P+ T + G +
Sbjct: 1588 TDTSSASKGDTTPLPVTSPSSASTG-HTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHA 1646
Query: 710 VQPVGQAPAAVS---AVP---TGSQIANIGQQANIP-----TAVQQPSTQVPPSVIQQGA 758
+P++ S A P T + A+ G +P +A +T++P + + +
Sbjct: 1647 TPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSAS 1706
Query: 759 PPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQL 818
+ +P + G T P + S SS T P V + Q
Sbjct: 1707 TGQATPLPVTSLSSVSTGDTTPLP-------VTSPSSASTGHASPLLVTDASSASTGQAT 1759
Query: 819 PAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLI 878
P LP ++ TS VS+ + +P + + + P T V S S
Sbjct: 1760 P----LP----VTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTD----VSSAS----- 1802
Query: 879 ATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTI--SGDSGGMS 936
Q IPL T S+ S + DA A+ LP TI S SG +
Sbjct: 1803 -------TGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTT 1855
Query: 937 A--VSDGSSSSLAASASLFPLKVLPL----TTPLVDGEDESSS 973
+ V+D SS S + SL + TTPL + S+S
Sbjct: 1856 SLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSAS 1898
Score = 85.9 bits (211), Expect = 2e-16
Identities = 195/925 (21%), Positives = 318/925 (34%), Gaps = 123/925 (13%)
Query: 73 STSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQISASISSNNSIA 132
ST P P SL+ +S P+ T S Q T + +S S+S+ ++
Sbjct: 2762 STGHATPLPLTSLSSVSTGDTTPLPV----TDTSSASTGQATPLPVTSLS-SVSTGDTTP 2816
Query: 133 EDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSS-SEETLNNFQEAETPGAVSP 191
H L ++ S AT L + + SS S +T A
Sbjct: 2817 LPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIG 2876
Query: 192 NQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGH----------HLQHGHHHPSH 241
+ LP + + + G+A P H+ GH GH +P H
Sbjct: 2877 HATSLP------VTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLH 2930
Query: 242 VAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTGG 301
V S++ TG PV+ S + + PV S+V S+G + + ++TG
Sbjct: 2931 VTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSV-STGDTTPLPVTSPSSASTGH 2989
Query: 302 IGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNV 361
VT TS+ + TA+ VTS+ + T+ +P S G + + V
Sbjct: 2990 TTPLPVTDTSSASTGQATAL-----PVTSTSSASTG-DTTPLPVTDTSSASTGQATPLPV 3043
Query: 362 NILSGMGNGTISSSAAVSSVPNAAAG-------MTGGSVSSQQQQPTVNTSRFRVVKLDS 414
LS + G ++ V+S +A+ G S S+ Q P TS V D+
Sbjct: 3044 TSLSSVSTGD-TTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDT 3102
Query: 415 SSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSV 474
+ P T ++P T+ T + VT + +G + S V
Sbjct: 3103 TPLPVTSPSSAST---GHATSLPVTD----TSSASTGDTTSLPVTDTSSAYTGDTTSLPV 3155
Query: 475 STLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVS 534
+ S S G T ++ + P L + STG + V+
Sbjct: 3156 TDTS-------SSSTGDTTPLLVTETSSVSTGHATPLL----VTDASSASTGHATPLHVT 3204
Query: 535 IPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQ 594
P S S + PVP+ T S +TG +P+ V G++SA
Sbjct: 3205 SPSSASTGDTT------------------PVPVTDTSSVSTG-HATPLPVTGLSSA---- 3241
Query: 595 PSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVST---QMAPGHVKSV--- 648
+ + P S A+ TPLP + G P+ T + GH +
Sbjct: 3242 STGDTTRLPVTDISSASTGQATPLP-VTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVT 3300
Query: 649 -TQNPASEYVQQQPILQTAMSS---------GQPSSAGVGAGTTVIPVAQPQGIQLPVQP 698
T + ++ + P+ T+ +S SSA G TT +PV P
Sbjct: 3301 STSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTG-DTTPLPVTSPSSASTGHTT 3359
Query: 699 TAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQP-----STQVPPSV 753
P+ AS P TG+ A+ G +P +T +P +
Sbjct: 3360 PLHVTIPSSASTGDTSTLPV------TGASSASTGHATPLPVTDTSSVSTGHATPLPVTS 3413
Query: 754 IQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGI 813
+ + + +P G T P + S SS+ T P V +
Sbjct: 3414 LSSVSTGDTTPLPVTDASSASTGQATPLP-------VTSLSSVSTGDTTPLLVTDASSVS 3466
Query: 814 VSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVS 873
P + S++S T+++ T S SA T P + + G+ +
Sbjct: 3467 TGHATPLPVTDTSSASTGDTTRLPVTDTS---SASTGQATPLPVTSLSSVSTGD-----T 3518
Query: 874 QPPLIATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTI-SGDS 932
P L+ +++ PL T S+ S + D A+ LP TI S S
Sbjct: 3519 TPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSS 3578
Query: 933 GGMSAVSDGSSSSLAASASLFPLKV 957
G + +S+S ++ + PL V
Sbjct: 3579 SGHTTPLPVTSTSSVSTGHVTPLHV 3603
Score = 81.3 bits (199), Expect = 5e-15
Identities = 174/803 (21%), Positives = 294/803 (36%), Gaps = 142/803 (17%)
Query: 261 KLSTTGSSDSITPVAPTSAVSSSG--SPASVMTNMRAPSTTGGIGINSVTGTSTVNNVNI 318
++S + +++TPV ++ +SS +P+ ++ PS G + + S+V+N +
Sbjct: 334 RVSQINTLNTLTPVTTSTVLSSPSGFNPSGTVSQETFPS-----GETTTSSPSSVSNTFL 388
Query: 319 TAVGSFN-PNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTISSSAA 377
F P S LGN ++ ++ G S + + + + T+S++ +
Sbjct: 389 VTSKVFRMPTSRDSTLGNTEETSLSVS---------GTISAITSKVSTIWWSDTLSTALS 439
Query: 378 VSSVP-----------NAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFK-KGR-- 423
SS+P + A TG P V+ F + + + F KG
Sbjct: 440 PSSLPPKISTAFHTQQSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTT 499
Query: 424 WTCTEFYEKENAVPATEGVLINK---VVETVKQNPIEVTSERESTSGSSVSSSVSTL--- 477
W+ TE AT V N T+ + P +V++ E ++ SS +TL
Sbjct: 500 WSQTELPSTSTGA-ATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKT 558
Query: 478 ---------SHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFG----- 523
+ T + G + +P+ V Q + P L T QQ+
Sbjct: 559 TGAGAQTQWTQETGTTGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNH 618
Query: 524 ------STGPQSIPAVS------IPQSISQSQISQ----------VQLQSQELSYQQKQG 561
ST PQ PAVS PQ+ +SQ ++ V +
Sbjct: 619 STIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSP 678
Query: 562 LQPVPLQA-TMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPL-- 618
+ VP A T+SAAT P+P T A P+ + A P + P T L
Sbjct: 679 SEIVPQDAPTISAATTFAPAPTGDGHTTQA----PTTALQAAPSSHDATLGPSGGTSLSK 734
Query: 619 -------------PGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQT 665
PG P Q S +P ++T +E + QT
Sbjct: 735 TGALTLANSVVSTPGGPEGQWTS-------ASASTSPDTAAAMTHTHQAESTEASGQTQT 787
Query: 666 ---AMSSGQPSSAGVG----AGTTVIPVAQPQGIQLPVQPTAVPAQPAG-----ASVQPV 713
A S + +SAG +G + + +GI + T + P+ S +
Sbjct: 788 SEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTEL 847
Query: 714 GQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGII 773
A A+ A+P + +A+ + + ST P+ + P+S P +T I
Sbjct: 848 LSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPT---GQSSPTSPSASPQETAAI 904
Query: 774 HQGVQTSAPSLPQ---QLVIASQS--SLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSAS 828
+ QT + + +ASQ+ + TVPP P + + G+ S Q + PS S
Sbjct: 905 SRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSI--TSTGLTSPQTETHTLSPSGS 962
Query: 829 SISVTSQVSSTGP----SGMPSAPTNLVPPQNIAQTPATQNGNLVQ-SVSQPPLIATNTN 883
+ T+ + S + SA T P ++ + G+ V+ P ++T
Sbjct: 963 GKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHT 1022
Query: 884 LPL----------AQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQT-ISGDS 932
PL PL T FS+ S + + D A+ + LP T +S S
Sbjct: 1023 TPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSAS 1082
Query: 933 GGMSA---VSDGSSSSLAASASL 952
G + V+D SS+S + SL
Sbjct: 1083 TGDTTPLPVTDTSSASTGHATSL 1105
Score = 79.0 bits (193), Expect = 2e-14
Identities = 185/812 (22%), Positives = 293/812 (36%), Gaps = 110/812 (13%)
Query: 235 GHHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMR 294
GH P HV + S++ TG + PV+ S + + PV TS+VS+ + +T++
Sbjct: 3356 GHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLS 3415
Query: 295 APST--TGGIGINSVTGTST--VNNVNITAVGSFNPNVTSSMLGNVNISTSN-----IPS 345
+ ST T + + + ST + +T++ S + T+ +L S S +P
Sbjct: 3416 SVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPV 3475
Query: 346 AAGVSVGPGVTSGVNVNILSGMGNG-----TISSSAAVSS-------VPNAAAGMTGGS- 392
S G T+ + V S G ++S ++VS+ V +A++ TG +
Sbjct: 3476 TDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHAT 3535
Query: 393 ---VSSQQQQPTVNTSRFRVVKLDSSSE----------PFKKGRWTCTEFYEKENAVPAT 439
V+ T +T+R V S+S P T + +T
Sbjct: 3536 PLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVST 3595
Query: 440 EGVLINKV-----VETVKQNPIEVTSERESTSGSSV------SSSVSTLSHYT----ESV 484
V V T P+ VTS +++G + +SSVST H T
Sbjct: 3596 GHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVST-GHATPLPVTDA 3654
Query: 485 GSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIP------------- 531
S G T + Q P L +L + G T P +
Sbjct: 3655 SSASTGDTTPLPVTDTSSASTGQATP-LPVTSLSSVSTGDTTPLPVTDASSASTGHATPL 3713
Query: 532 AVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATG-IQPSPVNVVGVTSA 590
V+IP S+S + + S S P+P+ SA+TG P PV S
Sbjct: 3714 PVTIPSSVSTGDTMPLPVTSP--SSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSAST 3771
Query: 591 LGQQP-------SISSLAQPQLP---YSQAAPPVQTPLPGAPPPQQLQYGQQQPMVST-- 638
P S S+ +LP S A+ TPLP G P+ T
Sbjct: 3772 RHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHATPLP-VTSTSSASTGDTTPLPVTDT 3830
Query: 639 -QMAPGHVKS--VTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLP 695
++ GH S VT ++ P+ T SS A T+ V+ LP
Sbjct: 3831 SSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLP 3890
Query: 696 VQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQ 755
V + A A+ PV +A + T + N +++ T P PS
Sbjct: 3891 VTSPS-SASTGHATPVPVTSTSSASTGDTTPLPVTN---ASSLSTGHATPLHVTSPSSAS 3946
Query: 756 QGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVS 815
+G + +P G T P + S SS+ T P V +
Sbjct: 3947 RG---DTSTLPVTDASSASTGHATPLP-------LTSLSSVSTGDTTPLPVTDTSSASTG 3996
Query: 816 QQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQP 875
Q P + S+ S T+ + T PS S T +P + A + +T +G P
Sbjct: 3997 QATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTD-ASSVSTGHGT-------P 4048
Query: 876 PLIATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQT-ISGDSGG 934
+ + ++ PL T S+ S A + D A+ LP T +S S G
Sbjct: 4049 LPVTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTG 4108
Query: 935 MS---AVSDGSSSSLAASASLFPLKVLPLTTP 963
+ AVS +S+S +S S ++ +TTP
Sbjct: 4109 HATPLAVSSATSASTVSSDSPLKMETPGMTTP 4140
Score = 69.7 bits (169), Expect = 1e-11
Identities = 201/984 (20%), Positives = 329/984 (33%), Gaps = 132/984 (13%)
Query: 70 AASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQISASISSNN 129
+++ST P P S + S P+ T TS+ P ++S+S+ +
Sbjct: 1927 SSASTGDTTPLPVTSPSSASSGHTTPLPV----TDASSVPTGHATSL-PVTDASSVSTGH 1981
Query: 130 SIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSS-SEETLNNFQEAETPGA 188
+ + H L ++ VS +AT L SS S +T A
Sbjct: 1982 ATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSA 2041
Query: 189 VSPNQPHLPQPHLPHLPQQNVV----------INGNAHPHHLHHHHQIHHGH-------- 230
+ LP L + + G+A P + + GH
Sbjct: 2042 STGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTD 2101
Query: 231 --HLQHGHHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPAS 288
+ GH HV AS+ TG PV+ S + + PV TS+V S+G S
Sbjct: 2102 ASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSV-STGHATS 2160
Query: 289 VMTNMRAPSTTGGIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAG 348
+ + ++TG VT TS+ + + T + P +S + + S +
Sbjct: 2161 LPVTDTSSASTGHATSLPVTDTSSASTGHATPL----PVTDTSSASTGQATPLPVTSPSS 2216
Query: 349 VSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNAAAG-MTGGSVSSQQQQPTVNTSRF 407
S G + V + G T V+S+ +A+ G T V+ T + +
Sbjct: 2217 ASTGHAIPLLVTDTSSASTGQAT---PLPVTSLSSASTGDTTPLPVTDASSVSTGHATSL 2273
Query: 408 RVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSG 467
V L S S +P T T P+ VT +++G
Sbjct: 2274 PVTSLSSVST-------------GDTTPLPVTS----PSSASTGHATPLHVTDASSASTG 2316
Query: 468 SSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGP 527
+ V++LS S G T + P L D S
Sbjct: 2317 HATPLPVTSLS-------SASTGDTTPLPVTSPSSASTGHATP------LHVTDASSVST 2363
Query: 528 QSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGV 587
+ + S S S L + S P+P+ T SA+TG + + V G+
Sbjct: 2364 GDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTG-HATHLPVTGL 2422
Query: 588 TSALGQQ------PSISSLAQ------PQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPM 635
+SA ++SS + P S A+ TPLPG + G P+
Sbjct: 2423 SSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGT-DTSSVSTGHTTPL 2481
Query: 636 VSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLP 695
+ T + T+ P + T + SA G TT +PV +
Sbjct: 2482 LVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTG-DTTPLPVTNASSLSTR 2540
Query: 696 VQPTAVPAQPAGASV-----QPVGQAPAAVS--AVP---TGSQIANIGQQANIP-----T 740
+ P+ AS PV AA + A P T + A+ G +P +
Sbjct: 2541 HATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYS 2600
Query: 741 AVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAP-----------SLPQQLV 789
A +T +P + + + +P T G T P + P +
Sbjct: 2601 ASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVT 2660
Query: 790 IASQSSLLTVPPQP-QGVEPVAQG-IVSQQLPAVSSLPSASSISVTSQVSSTGPSG---- 843
S +S P P V+ G S + SS+ + + S+ + S+ SG
Sbjct: 2661 SPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTP 2720
Query: 844 MPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQSLA 903
+P + V + P T ++ + P + +++ PL T S+ S
Sbjct: 2721 LPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTG 2780
Query: 904 QAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSL----AASASLFPLKVLP 959
+ D A+ LP T +S+VS G ++ L +SAS LP
Sbjct: 2781 DTTPLPVTDTSSASTGQATPLPVT------SLSSVSTGDTTPLPVTDTSSASTGHATSLP 2834
Query: 960 LT----------TPLVDGEDESSS 973
+T TPL D + S+S
Sbjct: 2835 VTDTSSASTGHATPLPDTDTSSAS 2858
Score = 60.5 bits (145), Expect = 8e-09
Identities = 221/1036 (21%), Positives = 352/1036 (33%), Gaps = 146/1036 (14%)
Query: 35 SGSASALNAAGTGVGSNATSSEDFPPPSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQ 94
+ ++SA T + SS + L +++ST P P SL+ +S
Sbjct: 1668 TSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTT 1727
Query: 95 AQPL-APGGTQMKKKSGFQITSVTPAQ------ISASISSNNSIAEDTE-SYDDLDESHT 146
P+ +P S +T + A + + +S+ S A T L + T
Sbjct: 1728 PLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSAST 1787
Query: 147 EDLSSSEILDVSLSRATDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPHLPQ 206
+D + + DVS S +T P +S + + P + + LP
Sbjct: 1788 DDTTRLPVTDVS-SASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLP---- 1842
Query: 207 QNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPVSRKLSTTG 266
V I +A H + + GH V AS+ TG PV+ + +
Sbjct: 1843 --VTIPSSASSGHTTSL-PVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTD--TNSA 1897
Query: 267 SSDSITPVAPTSAVS-SSGSPASVMTNMRAPSTTGGIGINSVTGTSTVNNVNITAVGSFN 325
S+ TP+ T A S S+G S+ + ++TG VT S+ ++ + T +
Sbjct: 1898 STGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPL---- 1953
Query: 326 PNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNAA 385
P +S + + ++ + A+ VS G V G+ T SSV
Sbjct: 1954 PVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQ 2013
Query: 386 AGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLIN 445
A T V+S T +T+ V S+S ++ +P T
Sbjct: 2014 A--TPLPVTSLSSASTGDTTPLPVTDTSSAST-------------GQDTPLPVTS----L 2054
Query: 446 KVVETVKQNPIEVTSERESTSGSSV------SSSVSTLSHYT-------ESVGSGEMGAP 492
V T P+ VTS +++G + +SSVST H T SV +G A
Sbjct: 2055 SSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVST-GHATSLLVTDASSVSTGHATAL 2113
Query: 493 TVVVQQQQQQQQQ-----QQQQPALQGVT--LQQMDFGSTGPQSIPAVSIPQSISQSQIS 545
V A G T L D S ++ + + S S
Sbjct: 2114 HVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGH 2173
Query: 546 QVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSA--------LGQQPSI 597
L + S P+P+ T SA+TG Q +P+ V +SA L S
Sbjct: 2174 ATSLPVTDTSSASTGHATPLPVTDTSSASTG-QATPLPVTSPSSASTGHAIPLLVTDTSS 2232
Query: 598 SSLAQ----PQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPA 653
+S Q P S A+ TPLP + G + T ++ T P
Sbjct: 2233 ASTGQATPLPVTSLSSASTGDTTPLP-VTDASSVSTGHATSLPVTSLSSVSTGDTTPLPV 2291
Query: 654 SEYVQQQPILQTAMSSGQPSSAGVG---------------AGTTVIPVAQPQ----GIQL 694
+ T + SSA G TT +PV P G
Sbjct: 2292 TSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHAT 2351
Query: 695 PVQPTAVPAQPAGASVQ-PVGQAPAAVSA----VP-TGSQIANIGQQANIP-----TAVQ 743
P+ T + G + PV + +A S +P T + A+ G +P +A
Sbjct: 2352 PLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSAST 2411
Query: 744 QPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQP 803
+T +P + + + + +P G T P + S SS T P
Sbjct: 2412 GHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLP-------VTSTSSASTGDTTP 2464
Query: 804 QGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPAT 863
+ P + + S+ S T+++ T PS SA T P + TP+
Sbjct: 2465 LPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPS---SASTGHTTPLPVTDTPSA 2521
Query: 864 QNGNLVQSVSQPPLIATN-TNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLV 922
G+ PL TN ++L L T S+ S A + D A+
Sbjct: 2522 STGDTT------PLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHAT 2575
Query: 923 GLPQTISGDSGGMSAVSDGSSSSLAA----SASLFPLKVLPLT------------TPLVD 966
LP T S+ S G ++ L SAS LP+T P+ D
Sbjct: 2576 PLPVT------STSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLPVTD 2629
Query: 967 GEDESSSGASVVAIDN 982
S+ A+ + + N
Sbjct: 2630 TSSASTGHATPLPVTN 2645
Score = 60.1 bits (144), Expect = 1e-08
Identities = 174/792 (21%), Positives = 276/792 (34%), Gaps = 105/792 (13%)
Query: 236 HHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRA 295
H H + AS P+S SR T A T+ SSSG+ + +
Sbjct: 772 HTHQAESTEASGQTQTSEPASSGSR-----------TTSAGTATPSSSGASGTTPSGSEG 820
Query: 296 PSTTGGIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGV 355
ST+G T S NP+ S + ST+ + SA+ V
Sbjct: 821 ISTSGE-----------------TTRFSSNPSRDS----HTTQSTTELLSASASHGAIPV 859
Query: 356 TSGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSS 415
++G+ +I+ G + T+ S A+ + P + T S S Q+ ++ + +
Sbjct: 860 STGMASSIVPGTFHPTL-SEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRG 918
Query: 416 SEPFKKGRWTCTEFYEKENAVPA-TEGVLINKVVETVKQNP-----------IEVTSERE 463
S+ F P+ T L + ET +P I +
Sbjct: 919 SDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLP 978
Query: 464 STSGSSVSSSVSTLSHYTE--SVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMD 521
T SS S+ +T H T+ SV +G P V P D
Sbjct: 979 VTYASSASTGHTTPLHVTDASSVSTGH-ATPLPVTSPSSVSTGHTTPLPV--------TD 1029
Query: 522 FGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSP 581
S + + + S S L + S + P+P+ + SA+TG +P
Sbjct: 1030 TSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTG-DTTP 1088
Query: 582 VNVVGVTSA-LGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQ-QLQYGQQQPMVST- 638
+ V +SA G S+ P S + TPLP + P+ T
Sbjct: 1089 LPVTDTSSASTGHATSL-----PVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDTS 1143
Query: 639 QMAPGHVK--SVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAG-TTVIPVAQPQ----G 691
++ GH VT ++ Q P+ T++SS V G TT +PV P G
Sbjct: 1144 SVSTGHTTPLHVTDASSASTGQATPLPVTSLSS-------VSTGDTTPLPVTSPSSASTG 1196
Query: 692 IQLPVQPTAVPAQPAG-ASVQPVGQAPA-----AVSAVPTGSQIANIGQQANIP-TAVQQ 744
P+ T + G A+ PV A + A S T A+ G +P T
Sbjct: 1197 HATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSS 1256
Query: 745 PSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQ 804
ST S++ +S V T + +++ L + S SS T P
Sbjct: 1257 ASTGQATSLL---VTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPL 1313
Query: 805 GVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTN--LVPPQNIAQT-- 860
V ++ +P + PS++S T+ + T S + + T V + A T
Sbjct: 1314 PVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQ 1373
Query: 861 ----PATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRA 916
P T ++ + P + + ++ PL T S+ S A + DA
Sbjct: 1374 ATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSV 1433
Query: 917 AEPSLVGLPQTI-SGDSGGMSA---VSDGSSSSLAASASLFPLKVLPL----TTPLVDGE 968
+ LP TI S S G + V+D SS+S + SL + TTPL
Sbjct: 1434 STDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTS 1493
Query: 969 DESSSGASVVAI 980
S+S V +
Sbjct: 1494 TSSASTGHVTPL 1505
Score = 40.8 bits (94), Expect = 0.007
Identities = 83/383 (21%), Positives = 145/383 (37%), Gaps = 52/383 (13%)
Query: 114 TSVTPAQISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSS 173
T+ P ++S+S+ ++ + S H L ++ VS AT L P S+S
Sbjct: 3822 TTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPL--PVTSTS 3879
Query: 174 EETLNNFQEAETPGAVSPNQPHL-PQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHL 232
+ + S + H P P + + G+ P + + L
Sbjct: 3880 SVSTGHATPLPVTSPSSASTGHATPVP----VTSTSSASTGDTTPL------PVTNASSL 3929
Query: 233 QHGHHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTN 292
GH P HV S++ G + PV+ S + + P+ S+VS+ + +T+
Sbjct: 3930 STGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTD 3989
Query: 293 MRAPSTTGG-----IGINSV-TGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSN---I 343
+ ST ++SV TG +T V I + S + + ++ST + +
Sbjct: 3990 TSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPL 4049
Query: 344 PSAAGVSVGPGVTSGVNVNILSGMGNG-------TISSSAA--------VSSVPNAAAG- 387
P + S G T+ + V S G T +SSA+ V+S+ + + G
Sbjct: 4050 PVTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGH 4109
Query: 388 MTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKK---GRWTCTEFYEKENAVPATEGVLI 444
T +VSS TV++ ++ + P K GR T T + P T +I
Sbjct: 4110 ATPLAVSSATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTAT------SPPPTTSQTII 4163
Query: 445 NKVVETVKQN-----PIEVTSER 462
+ + T PI + ER
Sbjct: 4164 STIPSTAMHTRSTAAPIPILPER 4186
Score = 37.7 bits (86), Expect = 0.059
Identities = 150/767 (19%), Positives = 270/767 (35%), Gaps = 98/767 (12%)
Query: 249 ITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTGGIGINSVT 308
ITG ++PV+ STT + + + A + + S +S ++ TT +++T
Sbjct: 35 ITGSKTAAPVTSTGSTTATLEGQSTAASSRTSNQDISASSQNHQTKSTETTSKAQTDTLT 94
Query: 309 --------GTSTVNNVNITA-----VGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGV 355
+ +V+NV TA SF +VT++++ + T + ++ ++G
Sbjct: 95 QMMTSTLFSSPSVHNVMETAPPDEMTTSFPSSVTNTLM--MTSKTITMTTSTDSTLG--- 149
Query: 356 TSGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTS--------RF 407
N S G SS V+S + AG G S ++ + +TS R
Sbjct: 150 ----NTEETSTAGT---ESSTPVTSAVSITAGQEGQSRTTSWRTSIQDTSASSQNHWTRS 202
Query: 408 RVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSG 467
+S + + F + V T + ET + VT+ TS
Sbjct: 203 TQTTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSVTNTSMMTSE 262
Query: 468 --SSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGST 525
+ +S+ STL + E+ G+ V + Q PA F T
Sbjct: 263 KITVTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVTFDPEGQSPA---------TFSRT 313
Query: 526 GPQSIPAVS---IPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPS-P 581
Q A S QS+ +++SQ+ + L PV +S+ +G PS
Sbjct: 314 STQDTTAFSKNHQTQSVETTRVSQINTLNT---------LTPVTTSTVLSSPSGFNPSGT 364
Query: 582 VNVVGVTSALGQQPSISSLAQPQLPYSQA--APPVQTPLPGAPPPQQLQYGQQQPMVSTQ 639
V+ S S SS++ L S+ P + G L ++++
Sbjct: 365 VSQETFPSGETTTSSPSSVSNTFLVTSKVFRMPTSRDSTLGNTEETSLSVSGTISAITSK 424
Query: 640 MAP---GHVKSVTQNPAS--------EYVQQQPILQTAMSSGQPSSAGVGAG-------- 680
++ S +P+S + QQ +T + SS G
Sbjct: 425 VSTIWWSDTLSTALSPSSLPPKISTAFHTQQSEGAETTGRPHERSSFSPGVSQEIFTLHE 484
Query: 681 TTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSA--VP-TGSQIANIGQQAN 737
TT P + T +P+ GA+ + V P+ +A +P S+++ IG+
Sbjct: 485 TTTWPSSFSSKGHTTWSQTELPSTSTGAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGE 544
Query: 738 IPTAVQQPSTQVPPSV-------IQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVI 790
PT ST +P + Q + + + + + + Q ++T+ ++
Sbjct: 545 -PTTYSSHSTTLPKTTGAGAQTQWTQETGTTGEALLSSPSYSVTQMIKTATSPSSSPMLD 603
Query: 791 ASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTN 850
S +T P + Q+ PAVS + T+Q S T S P T
Sbjct: 604 RHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQ-RGHTQAPQTTQESQTTRSVSPMTDTK 662
Query: 851 LVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPL------AQQIPLSSTQFSAQSLAQ 904
V + T + + + + P + A T P Q P ++ Q + S
Sbjct: 663 TVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDA 722
Query: 905 AIGSQ--IEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAAS 949
+G ++ A + T G G ++ S +S AA+
Sbjct: 723 TLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAA 769
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 87.0 bits (214), Expect = 8e-17
Identities = 159/590 (26%), Positives = 230/590 (38%), Gaps = 104/590 (17%)
Query: 345 SAAGVSVGPGVTSG-VNVNILSGMGNGTISSSAAVSSVPNAAAGMT--GGSVSSQ--QQQ 399
S G S+ G SG V VN ++G+ T S + P A +T GGS +Q Q
Sbjct: 2582 SVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTPGGSAPAQVVHTQ 2641
Query: 400 PTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKV-VETVKQNPIEV 458
P R V +++ P T T+ +V A+ V N V+T ++ +
Sbjct: 2642 PPP-----RAVGSPATATPDLVSMAT-TQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQ 2695
Query: 459 TSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQ 518
S+ +G + T +H+ +++QQQQQQQQQQQQ Q Q
Sbjct: 2696 VSQ---ATGVQLPGKTITPAHFQ-------------LLRQQQQQQQQQQQQQQQQQQQQQ 2739
Query: 519 QMDFGSTGPQSIPAVSIP----QSISQSQISQV-QLQSQELSYQQKQGLQPVPLQATMSA 573
Q + V +P Q+ S +QI V +L + L QKQ LQ +P Q
Sbjct: 2740 QQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQ-MPPQPPPPQ 2798
Query: 574 ATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGA----PPPQQLQY 629
A P P V V + +QP S V P PGA LQ
Sbjct: 2799 AQSAPPQPTAQVQVQT-----------SQPPQQQSPQLTTVTAPRPGALLTGTTVANLQV 2847
Query: 630 GQQQPMVSTQM-APGHVKSVTQNPASEYVQQQPILQT--------------------AMS 668
+ + ++Q+ A G +++ PA + + P++ +++
Sbjct: 2848 ARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVA 2907
Query: 669 SGQPSSAGVGAGTTVIPVAQPQGIQ--LPVQPTAVPAQPAGASVQP-VGQAPAAVSAVPT 725
GQP A AG TV VAQP +Q L ++ AV Q A +QP Q PAAV T
Sbjct: 2908 IGQPQKA---AGQTV--VAQPVHMQQLLKLKQQAVQQQKA---IQPQAAQGPAAVQQKIT 2959
Query: 726 GSQIANIGQQANIPTAVQQP-STQVPPSVIQQG--APPSSQVVPPAQTGIIHQGVQTSAP 782
QI G Q + A Q TQ + I Q + QV Q + Q VQ P
Sbjct: 2960 AQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTP 3019
Query: 783 -SLPQQLVIASQSSLLTVPPQPQGV---EPVAQGIVSQQLPAVSSLPSASSISVTSQ--- 835
+ QQ+ ASQ + PQ V + A G Q +PAV++ + Q
Sbjct: 3020 VASIQQVASASQQA------SPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVV 3073
Query: 836 VSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLP 885
+++ P P AP N AQ PA+ + Q Q + A P
Sbjct: 3074 TTASAPLQTPGAP-------NPAQVPASSDSPSQQPKLQMRVPAVRLKTP 3116
Score = 60.5 bits (145), Expect = 8e-09
Identities = 127/564 (22%), Positives = 196/564 (34%), Gaps = 109/564 (19%)
Query: 593 QQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPM--VSTQMAPGHVKSVTQ 650
QQP++ AQP P Q PP Q P P P PQ G Q P + Q P
Sbjct: 2499 QQPAV---AQPPPPQPQPPPPPQQPPPPLPQPQAA--GSQPPAGPPAVQPQPQPQPQTQP 2553
Query: 651 NPASEYVQQQPILQTAMS------------SGQPSSAGVGAGTTV------IPVAQPQGI 692
P + QP + T S +G G +G + +P A Q I
Sbjct: 2554 QPVQAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSI 2613
Query: 693 Q----LPVQPTAV-------PAQ------PAGASVQPVGQAPAAVSAVPTGS--QIANIG 733
PV P A+ PAQ P A P P VS T + ++
Sbjct: 2614 NKRLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVT 2673
Query: 734 QQANIP---TAVQQPSTQVPPSVIQ-QGAPPSSQVVPPAQTGII-------HQGVQTSAP 782
A + T VQ P+ + P V Q G + + PA ++ Q Q
Sbjct: 2674 ASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQ 2733
Query: 783 SLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPS 842
QQ Q T Q Q + Q Q+ AV L I + Q P
Sbjct: 2734 QQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQ 2793
Query: 843 GMPSAPTNLVPPQNIAQT-------PATQNGNLVQ-SVSQPPLIATNT---NLPLAQQIP 891
P PPQ AQ P Q+ L + +P + T T NL +A+
Sbjct: 2794 -PPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTR 2852
Query: 892 LSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASAS 951
+ ++Q AQ Q Q A+P +V +P + G +
Sbjct: 2853 VPTSQLQAQGQMQTQAPQPAQV-ALAKPPVVSVPAAVVSSPG----------------VT 2895
Query: 952 LFPLKVLPLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMY-------------A 998
P+ V ++ + G+ + ++G +VVA ++Q + L + + A
Sbjct: 2896 TLPMNVAGISVAI--GQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAA 2953
Query: 999 VREEV---EVLKEQIKELIEKNSQLEQENNLLKT-LASPEQLA---QFQAQLQTGSPPAT 1051
V++++ ++ ++ + +Q + L T ++ ++LA Q Q Q+Q P
Sbjct: 2954 VQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQV 3013
Query: 1052 TQ---PQGTTQPPAQPASQGSGPT 1072
Q P + Q A + Q S T
Sbjct: 3014 VQQQTPVASIQQVASASQQASPQT 3037
Score = 58.9 bits (141), Expect = 2e-08
Identities = 76/292 (26%), Positives = 109/292 (37%), Gaps = 64/292 (21%)
Query: 629 YGQQQPMVSTQMAP---------GHVKSVTQNPASEY-VQQQPILQTAMSSGQPSSAGVG 678
+ +QQ M ST MA GH V Q+P ++ V Q ++ TA P+
Sbjct: 465 FKRQQAMPSTGMAEQSKRPRLEVGHQGVVFQHPGADAGVPLQQLMPTAQGGMPPTPQAAQ 524
Query: 679 AGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAV--SAVPTGS--------- 727
Q Q Q T P Q A + P+ Q P + + VPT +
Sbjct: 525 LA------GQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQ 578
Query: 728 --QIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQV-VPPAQTGIIHQGVQT----- 779
Q+ Q IP QQP+ +P APPSSQ+ +PP+Q + V T
Sbjct: 579 QPQVVEAQTQLQIPVKTQQPNVPIP-------APPSSQLPIPPSQPAQLALHVPTPGKVQ 631
Query: 780 ----SAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSS------------ 823
SLPQ + S+ L V P P P+ S P S
Sbjct: 632 VQASQLSSLPQMVA----STRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPARSSPV 687
Query: 824 -LPSASSISVTSQVSSTGPSGMPSAPTN-LVPPQNIAQTPATQNGNLVQSVS 873
PS+++ S V+S P + SAPT P QN + + L + ++
Sbjct: 688 NRPSSATNKALSPVTSRTPGVVASAPTKPQSPAQNATSSQDSSQDTLTEQIT 739
Score = 42.0 bits (97), Expect = 0.003
Identities = 90/370 (24%), Positives = 136/370 (36%), Gaps = 102/370 (27%)
Query: 525 TGPQSIPAVSIPQSISQS----QISQVQLQS--QELSYQQKQGLQPVPLQATMSAATGIQ 578
+ PQS P+ I Q +++S Q + LQS + Q+ L P+PL + S
Sbjct: 49 SAPQS-PSYQIQQLMNRSPATGQNVNITLQSVGPVVGGNQQITLAPLPLPSPTSPGFQFS 107
Query: 579 PSP-------VNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQ 631
P + + VTS L QQ S QP QA V+ PG
Sbjct: 108 AQPRRFEHGSPSYIQVTSPLSQQVQTQSPTQPSPGPGQALQNVRAGAPG----------- 156
Query: 632 QQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAG-----VGAGTTVIPV 686
PG + + +P +V +++ S PSS G G+G T I
Sbjct: 157 ----------PG-LGLCSSSPTGGFVDASVLVRQISLS--PSSGGHFVFQDGSGLTQIAQ 203
Query: 687 AQPQGIQLPVQPTAV----PAQP---AGASVQPVG-QAPAAVSAVPTGSQIANIGQQANI 738
+Q P P V P+QP +G ++ +G Q+PAA G+ + + ++I
Sbjct: 204 GAQVQLQHPGTPITVRERRPSQPHTQSGGTIHHLGPQSPAAAG----GAGLQPLASPSHI 259
Query: 739 PTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLL- 797
TA +PP + S ++ Q ++ Q P LP+ L +L
Sbjct: 260 TTA------NLPPQI--------SSII---QGQLVQQQQVLQGPPLPRPLGFERTPGVLL 302
Query: 798 -----------TVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPS 846
T PP P A P +SSLP ++S G +GM
Sbjct: 303 PGAGGAAGFGMTSPPPPTSPSRTAVP------PGLSSLP----------LTSVGNTGMKK 346
Query: 847 APTNL--VPP 854
P L +PP
Sbjct: 347 VPKKLEEIPP 356
Score = 41.6 bits (96), Expect = 0.004
Identities = 78/323 (24%), Positives = 109/323 (33%), Gaps = 67/323 (20%)
Query: 601 AQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQ 660
A P P S AAP + P A PQ Y QQ M + +V Q+ Q
Sbjct: 30 AHPNPPPSPAAPFAPSASPSA--PQSPSYQIQQLMNRSPATGQNVNITLQSVGPVVGGNQ 87
Query: 661 PILQTAMSSGQPSSAGVGAGT--------------TVIPVAQPQGIQLPVQPTAVPAQP- 705
I + P+S G P++Q Q P QP+ P Q
Sbjct: 88 QITLAPLPLPSPTSPGFQFSAQPRRFEHGSPSYIQVTSPLSQQVQTQSPTQPSPGPGQAL 147
Query: 706 ----AGA--------SVQPVGQAPAA------VSAVPT---------GSQIANIGQQANI 738
AGA S P G A +S P+ GS + I Q A +
Sbjct: 148 QNVRAGAPGPGLGLCSSSPTGGFVDASVLVRQISLSPSSGGHFVFQDGSGLTQIAQGAQV 207
Query: 739 PTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTG--IIHQGVQTSAPSLPQQLVIASQSSL 796
+Q P T P +++ P P Q+G I H G Q+ A + L + S
Sbjct: 208 --QLQHPGT---PITVRERRPSQ----PHTQSGGTIHHLGPQSPAAAGGAGLQPLASPSH 258
Query: 797 LTVPPQPQGVEPVAQGIVSQQLPAVSS--LPSASSISVTSQVSSTGPSGM---------- 844
+T P + + QG + QQ + LP T V G G
Sbjct: 259 ITTANLPPQISSIIQGQLVQQQQVLQGPPLPRPLGFERTPGVLLPGAGGAAGFGMTSPPP 318
Query: 845 PSAPTNLVPPQNIAQTPATQNGN 867
P++P+ P ++ P T GN
Sbjct: 319 PTSPSRTAVPPGLSSLPLTSVGN 341
Score = 39.3 bits (90), Expect = 0.020
Identities = 55/219 (25%), Positives = 74/219 (33%), Gaps = 34/219 (15%)
Query: 681 TTVIPVAQPQGIQLPV----QPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQA 736
T+ P A+P +L QP +P G +V P +A T S
Sbjct: 1408 TSAAPAARPAAAKLKASRLFQPVQYGQKPEGRTVAFPSTHPPRTAAPTTAS--------- 1458
Query: 737 NIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGII------HQGVQTSA----PSLPQ 786
A Q P PP P + P QT HQ S+ P+ P
Sbjct: 1459 ---AAPQGPLRGRPPIATFSANPEAKAAAAPFQTSQASASAPRHQPASASSTAASPAHPA 1515
Query: 787 QL---VIASQSSLLTVPPQPQGVEPVA-QGIVSQQL----PAVSSLPSASSISVTSQVSS 838
+L A S+ PPQPQ A Q + Q+L A + LPS + + S
Sbjct: 1516 KLRAQTTAQASTPGQPPPQPQAPSHAAGQSALPQRLVLPSQAQARLPSGEVVKIAQLASI 1575
Query: 839 TGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPL 877
TGP + P V Q + L Q + PL
Sbjct: 1576 TGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTAGQPL 1614
Score = 35.0 bits (79), Expect = 0.38
Identities = 29/86 (33%), Positives = 33/86 (38%), Gaps = 13/86 (15%)
Query: 59 PPPSLLQPP------------PPAASSTSGPQP-PPPQSLNLLSQAQLQAQPLAPGGTQM 105
PPP QPP PPA PQP P PQ+ QA +AQP G
Sbjct: 2513 PPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSA 2572
Query: 106 KKKSGFQITSVTPAQISASISSNNSI 131
+G TSVT + S N I
Sbjct: 2573 AVLAGTIKTSVTGTSMPTGAVSGNVI 2598
Score = 33.9 bits (76), Expect = 0.85
Identities = 39/148 (26%), Positives = 53/148 (35%), Gaps = 23/148 (15%)
Query: 492 PTVVVQQQQQQQQQQQQQPALQGVTLQQMDF---------GSTGPQSIPAVSIPQSISQS 542
PT Q Q+Q QQQ G +Q G P +P ++ ++ +
Sbjct: 518 PTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFA 577
Query: 543 QISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPS-----------PVNVVGVTSAL 591
Q QV +L K VP+ A S+ I PS P V S L
Sbjct: 578 QQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQL 637
Query: 592 GQQPSISSLAQPQLPYSQAAPPVQTPLP 619
P + +A +LP APP PLP
Sbjct: 638 SSLPQM--VASTRLPV-DPAPPCPRPLP 662
Score = 33.9 bits (76), Expect = 0.85
Identities = 39/117 (33%), Positives = 51/117 (43%), Gaps = 16/117 (13%)
Query: 5 PESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPPPSLL 64
PE+ AAAA A A PR S S++A + A T+++ P
Sbjct: 1478 PEAKAAAAPFQTSQASASA-----PRHQPASASSTAASPAHPAKLRAQTTAQASTPG--- 1529
Query: 65 QPPP-PAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQ 120
QPPP P A S + Q PQ L L SQAQ + P G +K Q+ S+T Q
Sbjct: 1530 QPPPQPQAPSHAAGQSALPQRLVLPSQAQAR----LPSGEVVKIA---QLASITGPQ 1579
Score = 33.9 bits (76), Expect = 0.85
Identities = 39/136 (28%), Positives = 49/136 (36%), Gaps = 31/136 (22%)
Query: 495 VVQQQQ-----QQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQL 549
VVQQQ QQ QQ + Q V L Q Q IPAV+ + Q+
Sbjct: 3013 VVQQQTPVASIQQVASASQQASPQTVALTQATAAGQQVQMIPAVT----------ATAQV 3062
Query: 550 QSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQ 609
Q+L QQ PLQ T P+P V + + QQP +
Sbjct: 3063 VQQKLIQQQVVTTASAPLQ------TPGAPNPAQVPASSDSPSQQPKL----------QM 3106
Query: 610 AAPPVQTPLPGAPPPQ 625
P V+ P PP Q
Sbjct: 3107 RVPAVRLKTPTKPPCQ 3122
Score = 31.6 bits (70), Expect = 4.2
Identities = 46/200 (23%), Positives = 69/200 (34%), Gaps = 40/200 (20%)
Query: 589 SALGQQPSISS--LAQPQLPYS-QAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHV 645
SA QP+ +S A P P +A Q PG PPPQ AP H
Sbjct: 1495 SAPRHQPASASSTAASPAHPAKLRAQTTAQASTPGQPPPQ-------------PQAPSHA 1541
Query: 646 KSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQP 705
+ P Q+ +L + + PS V+ +AQ I P A P P
Sbjct: 1542 AGQSALP------QRLVLPSQAQARLPSG-------EVVKIAQLASITGPQSRVAQPETP 1588
Query: 706 AGASVQ--PVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQ 763
Q + + + + G + G I +A QP + P V+ Q
Sbjct: 1589 VTLQFQGSKFTLSHSQLRQLTAGQPLQLQGSVLQIVSAPGQPYLRAPGPVVMQTV----- 1643
Query: 764 VVPPAQTGIIHQGVQTSAPS 783
+Q G +H + + P+
Sbjct: 1644 ----SQAGAVHGALGSKPPA 1659
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 87.0 bits (214), Expect = 8e-17
Identities = 114/401 (28%), Positives = 150/401 (37%), Gaps = 44/401 (10%)
Query: 497 QQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSY 556
QQQQQQQ QQQQQ ALQ QQ Q A QS Q Q V Q Q+L
Sbjct: 162 QQQQQQQFQQQQQAALQQQQQQQQQ------QQFQA---QQSAMQQQFQAVVQQQQQLQQ 212
Query: 557 QQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQT 616
QQ+Q + L Q + + QQ Q Q QA PP+Q
Sbjct: 213 QQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ 272
Query: 617 P--LPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQP-- 672
P PPP Q Q Q M TQ H + Q Q QP S QP
Sbjct: 273 PPMQQPQPPPSQALPQQLQQMHHTQ----HHQPPPQPQQPPVAQNQPSQLPPQSQTQPLV 328
Query: 673 SSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQ-IAN 731
S A G + + ++ P+ P QP Q Q A V G Q I
Sbjct: 329 SQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITE 388
Query: 732 IGQQANIPTAVQQPST----QVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQ 787
Q + + P T +P S I G P +QV +Q+ + S+PS P Q
Sbjct: 389 ALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQV---SQSSL----PMLSSPS-PGQ 440
Query: 788 LVIASQSSLLTVPPQPQGVEPVAQ----------GIVSQQLPAVSSLPSASSISVTS--- 834
V QS P PQ +P +Q S LP+ S PS S ++ +
Sbjct: 441 QVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQN 500
Query: 835 -QVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQ 874
V S GP P P++++ P +Q Q + ++ +S+
Sbjct: 501 FSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSK 541
Score = 58.5 bits (140), Expect = 3e-08
Identities = 121/433 (27%), Positives = 159/433 (36%), Gaps = 78/433 (18%)
Query: 523 GSTG--PQSIPAVSIPQSISQSQISQVQLQSQELS--YQQKQGLQPVPLQATMSAATGIQ 578
G++G P S+ VS +Q Q+ QV LQ Q+ +QQ+Q QA + Q
Sbjct: 132 GTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQ-------QAALQQQQQ-Q 183
Query: 579 PSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVST 638
SA+ QQ Q QL Q L QQ+Q QQQ
Sbjct: 184 QQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKL-HHQNQQQIQQQQQQLQRIA 242
Query: 639 QMAPGHVKSVTQNPASEYVQ----QQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQ- 693
Q+ + Q + Q Q PI Q M QP + A PQ +Q
Sbjct: 243 QLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPS----------QALPQQLQQ 292
Query: 694 ----LPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQ----------ANIP 739
QP P QP A QP Q P P SQ + Q P
Sbjct: 293 MHHTQHHQPPPQPQQPPVAQNQP-SQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAP 351
Query: 740 TAVQQPSTQVPPSVIQ-----QGAPPSSQVVPPAQ---TGIIHQGVQTSAPSLPQQLVIA 791
VQQP Q P V Q Q A + V P Q + G+ A P V A
Sbjct: 352 MVVQQPPVQ--PQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSA 409
Query: 792 SQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSS-------TGPSGM 844
SS + P G +P+AQ VSQ SSLP SS S QV + PS
Sbjct: 410 IPSSSI-----PLGRQPMAQ--VSQ-----SSLPMLSSPSPGQQVQTPQSMPPPPQPSPQ 457
Query: 845 PSAPTNLVPPQNIAQTPATQNGNLVQS----VSQPPLIA-TNTNLPLAQQIPLSSTQFSA 899
P P++ P N++ PA + + S SQ P+ A T N + PL++ +
Sbjct: 458 PGQPSS-QPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPS 516
Query: 900 QSLAQAIGSQIED 912
++ A SQ E+
Sbjct: 517 SVMSPAGSSQAEE 529
Score = 36.2 bits (82), Expect = 0.17
Identities = 47/207 (22%), Positives = 70/207 (33%), Gaps = 21/207 (10%)
Query: 29 PRRGSGS--GSASALNAAGTGVGSNATSSEDFPPPSLLQPPPPAASSTSGPQPPPP---- 82
P RG G G +L A G + + S + P S + P A ST+ PQ
Sbjct: 102 PPRGPGQSLGGMGSLGAMGQPM---SLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQV 158
Query: 83 --QSLNLLSQAQLQAQPLAPGGTQMKKKSGFQIT-SVTPAQISASISSNNSIAEDTESYD 139
Q Q Q Q Q Q +++ FQ S Q A + + + +
Sbjct: 159 ALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQ 218
Query: 140 DLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQP 199
L + H ++ + L R L ++ ++ Q+ QP + QP
Sbjct: 219 HLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQP 278
Query: 200 HLP---HLPQQNVVINGNAHPHHLHHH 223
P LPQQ HH HH
Sbjct: 279 QPPPSQALPQQ------LQQMHHTQHH 299
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 83.2 bits (204), Expect = 1e-15
Identities = 204/855 (23%), Positives = 324/855 (37%), Gaps = 158/855 (18%)
Query: 276 PTSAVSSSGSPASVMTNMRAPSTTGGIGINSVTGTSTVNNVNITAVGS-------FNPNV 328
PT +S+ SP S T+ +P+ + S + T+ V T VGS N N
Sbjct: 1925 PTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNF 1984
Query: 329 TSSMLGNVNISTSN-------------IPSAAGVSVGPGV-----TSGVNVNILSGMGNG 370
+ V SN IPS+ G S T+ V + + G
Sbjct: 1985 HQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGG 2044
Query: 371 TISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFY 430
T S+S ++ P GMT + + QQ T+ + R + P + T+
Sbjct: 2045 TTSNSQVITG-PQIRPGMT--VIRTPLQQSTLGKAIIRTPVMVQPGAP----QQVMTQII 2097
Query: 431 EKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVS------------TLS 478
+ P + V TV P + S +TS S++ SS S T++
Sbjct: 2098 RGQ---PVSTAV---SAPNTVSSTPGQ-KSLTSATSTSNIQSSASQPPRPQQGQVKLTMA 2150
Query: 479 HYTE-SVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGP-QSIPAVSIP 536
T+ + G G TVV+Q Q Q Q Q P QGVT+ GP Q + ++P
Sbjct: 2151 QLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIP--QGVTV------LPGPGQQLMQAAMP 2202
Query: 537 QSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSA-LGQQP 595
Q + P+ AT ++ T V T+A G+Q
Sbjct: 2203 NGTVQRFL-----------------FTPLATTATTASTT------TTTVSTTAAGTGEQR 2239
Query: 596 SISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASE 655
Q Q+ + PP Q+ G + QP + A ++ Q+PA
Sbjct: 2240 QSKLSPQMQVHQDKTLPPAQSSSVGP--------AEAQPQTAQPSAQPQPQTQPQSPAQP 2291
Query: 656 YVQQQPIL--QTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQ-- 711
VQ QP + QT +SS PS AQP Q A +QP ++VQ
Sbjct: 2292 EVQTQPEVQTQTTVSSHVPSE------------AQPTHAQSSKPQVAAQSQPQ-SNVQGQ 2338
Query: 712 -PVG-QAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQ---QGAPPSS-QVV 765
PV Q+P+ P+ + GQQ+ + T QP P + +Q QG P S QV
Sbjct: 2339 SPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQ 2398
Query: 766 PPAQT---GIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVS 822
QT G V S+PS PQ + Q ++ VP Q V+ ++Q I SQ
Sbjct: 2399 SSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQ-IQSQ------ 2451
Query: 823 SLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNT 882
V +Q+ + SG+P L P I Q+ A Q + +Q+V +
Sbjct: 2452 ---------VVAQIQAQ-QSGVPQ-QIKLQLPIQIQQSSAVQT-HQIQNVVTVQAASVQE 2499
Query: 883 NLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGS 942
L QQ+ + Q I + E +A+ S + Q + + + +
Sbjct: 2500 QLQRVQQL----RDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKK 2555
Query: 943 SSSLAA----SASLFPLKVLPLTTPLVDGEDESSS--GASVVAIDNKIEQAMDLVKSHLM 996
S + A + +V+ +D E++ ++ +++ K + S L+
Sbjct: 2556 SMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALL 2615
Query: 997 YAVREEV--EVLKEQIKELIEKNSQLEQENNLLKTLASPE-----QLAQFQAQLQTGSPP 1049
+ +E++ E+LK+ + L++K+ Q+E + L + L + QLAQ A + PP
Sbjct: 2616 FKHKEQLRAEILKK--RALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATA-VAAPCPP 2672
Query: 1050 ATTQPQGTTQPPAQP 1064
T P PP P
Sbjct: 2673 VTPAPPAPPAPPPSP 2687
Score = 50.4 bits (119), Expect = 9e-06
Identities = 105/447 (23%), Positives = 156/447 (34%), Gaps = 78/447 (17%)
Query: 263 STTGSSDSITPV-----APTSAVSSSGSPASVMTNMRAPSTTGGI-GINSVTGTSTVNNV 316
ST G + TPV AP ++ V T + AP+T G S+T ++ +N+
Sbjct: 2071 STLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNI 2130
Query: 317 NITAVGSFNPN-----VTSSMLGNVNISTSNIPSAAGVSVGPGVTSGV------NVNILS 365
+A P +T + L + V G G T+G V +L
Sbjct: 2131 QSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLP 2190
Query: 366 GMG---------NGTI--------SSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFR 408
G G NGT+ +++A +S T Q+Q S
Sbjct: 2191 GPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQS---KLSPQM 2247
Query: 409 VVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPI--EVTSERESTS 466
V D + P + E A P T +T Q+P EV ++ E +
Sbjct: 2248 QVHQDKTLPPAQSSSVGPAE------AQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQT 2301
Query: 467 GSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTG 526
++VSS V + + T + S P V Q Q Q Q Q +Q +
Sbjct: 2302 QTTVSSHVPSEAQPTHAQSS----KPQVAAQSQPQSNVQGQSPVRVQSPS---------- 2347
Query: 527 PQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVG 586
Q+ S P +S Q SQVQ + QP+P+Q S Q P +
Sbjct: 2348 -QTRIRPSTPSQLSPGQQSQVQTTTS----------QPIPIQPHTSLQIPSQGQPQSQPQ 2396
Query: 587 VTSAL-----GQ---QPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVST 638
V S+ GQ Q ++SS ++PQL Q P V Q L Q Q +
Sbjct: 2397 VQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQI 2456
Query: 639 QMAPGHVKSVTQNPASEYVQQQPILQT 665
Q V + +QQ +QT
Sbjct: 2457 QAQQSGVPQQIKLQLPIQIQQSSAVQT 2483
Score = 39.3 bits (90), Expect = 0.020
Identities = 100/449 (22%), Positives = 147/449 (32%), Gaps = 80/449 (17%)
Query: 631 QQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVI---PVA 687
QQ Q P + + T +P S Q M + P S V GT ++ V
Sbjct: 1914 QQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVA--PISGSVTTGTKMVLTTKVG 1971
Query: 688 QPQGIQLPVQP-------TAVPAQPAGASVQPVGQAPAAVSAVPTG-SQIANIGQQANIP 739
P + T V + + V V Q + TG SQ Q
Sbjct: 1972 SPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTA 2031
Query: 740 TAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTV 799
T +P+T G +SQV+ Q I G+ L QQ + V
Sbjct: 2032 TVTIRPNTSG-----SGGTTSNSQVITGPQ---IRPGMTVIRTPL-QQSTLGKAIIRTPV 2082
Query: 800 PPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQ 859
QP + V I+ Q P ++++S + VSST P +
Sbjct: 2083 MVQPGAPQQVMTQIIRGQ-------PVSTAVSAPNTVSST--------------PGQKSL 2121
Query: 860 TPATQNGNLVQSVSQPPLIATN-TNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAE 918
T AT N+ S SQPP L +AQ L+ Q L I Q + +
Sbjct: 2122 TSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQ--- 2178
Query: 919 PSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPLTTPLVDGEDESSSGASVV 978
L +PQ ++ G + + + LF PL T +++ ++
Sbjct: 2179 --LQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFT----PLATTATTASTTTTTVSTTA 2232
Query: 979 AIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQ 1038
A EQ + + Q+ Q+ L +S +
Sbjct: 2233 AGTG-------------------------EQRQSKLSPQMQVHQDKTLPPAQSS--SVGP 2265
Query: 1039 FQAQLQTGSPPATTQPQGTTQPPAQPASQ 1067
+AQ QT P A QPQ Q PAQP Q
Sbjct: 2266 AEAQPQTAQPSAQPQPQTQPQSPAQPEVQ 2294
Score = 37.7 bits (86), Expect = 0.059
Identities = 41/182 (22%), Positives = 69/182 (37%), Gaps = 43/182 (23%)
Query: 68 PPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPG----GTQMKKKSGFQITSVTP----- 118
PPA SS+ GP PQ+ +Q Q Q QP +P TQ + ++ ++S P
Sbjct: 2256 PPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQP 2315
Query: 119 -------------AQISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSL------ 159
+Q +++ + + + S + S LS + V
Sbjct: 2316 THAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPI 2375
Query: 160 -----------SRATDLGEPERSSSEETLNNFQEAETPGAVSPNQPHL----PQPHLPHL 204
S+ +P+ SS +TL++ Q SP++P L PQP + +
Sbjct: 2376 PIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAV 2435
Query: 205 PQ 206
PQ
Sbjct: 2436 PQ 2437
Score = 33.5 bits (75), Expect = 1.1
Identities = 51/227 (22%), Positives = 89/227 (39%), Gaps = 29/227 (12%)
Query: 3 QPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPPPS 62
+PP+ AA AA A P P G G S G+ G A + + P +
Sbjct: 7 RPPKQPAAPAAERCAPAPPPPPPP--PTSGPIGGLRS--RHRGSSRGRWAAAQAEVAPKT 62
Query: 63 LLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQIS 122
L P +SS P PPPP + + A + GG G + T A+ +
Sbjct: 63 RLSSPRGGSSSRRKPPPPPPAPPS--TSAPGRGGRGGGGGRTGGGGGGGHLARTTAARRA 120
Query: 123 AS-ISSNNSIAEDTESYDDL--DESHTEDLSSSEILDVSLSRATDLGE-------PERSS 172
+ + ++ +E+ E +D+ +E ED + E D ++ E PE
Sbjct: 121 VNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME 180
Query: 173 SEE------TLNNFQE----AETPGAVSPNQPHLPQPHLPHLPQQNV 209
++ T ++F+ + TPG +P + +P P L ++++
Sbjct: 181 DDDDDASYCTESSFRSHSTYSSTPGR---RKPRVHRPRSPILEEKDI 224
Score = 33.1 bits (74), Expect = 1.4
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 6/79 (7%)
Query: 60 PPSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPA 119
PP PP P A S P PP Q LLS P P +Q +K+ + +S
Sbjct: 2671 PPVTPAPPAPPAPPPSPPPPPAVQHTGLLS------TPTLPAASQKRKREEEKDSSSKSK 2724
Query: 120 QISASISSNNSIAEDTESY 138
+ +++ +DT+ Y
Sbjct: 2725 KKKMISTTSKETKKDTKLY 2743
>gi|225579127 Sin3A-associated protein, 130kDa isoform a [Homo
sapiens]
Length = 1083
Score = 81.6 bits (200), Expect = 4e-15
Identities = 186/919 (20%), Positives = 337/919 (36%), Gaps = 120/919 (13%)
Query: 38 ASALNAAGTGVGSNAT---SSEDFP---PPS--LLQPPPPAASSTSGPQPPPPQSLNLLS 89
A + A G G G SS+ FP PS L Q P A+S S P ++N S
Sbjct: 9 AGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDES 68
Query: 90 QAQLQA---QPLAPGGTQMKKKSGFQITSVTPAQISASISSNNSIAEDTESYDDLDESHT 146
+ + ++ + ++ + V P +S+++++A T +H
Sbjct: 69 GRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHL 128
Query: 147 ED---LSSSEILDVSLSRATDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPH 203
LS SE L + T P + TL+ + PG V+
Sbjct: 129 TPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLS--LPPKVPGQVTVTMES-------S 179
Query: 204 LPQQNVV----INGN-AHPHHLHHHHQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPV 258
+PQ + + I+G HP +LHH + + + + + ++ + G ++ V
Sbjct: 180 IPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAV 239
Query: 259 SRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNM-------RAPSTTGGIGINSVTGTS 311
SS T + PTS + ++ + + ++ R P TT +V T
Sbjct: 240 M------SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATV 293
Query: 312 TVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGT 371
+ + + + T S L +S + PSAA P + V I
Sbjct: 294 SATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPAL 353
Query: 372 ISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYE 431
+ + ++ TG V++ P + T+ S + T
Sbjct: 354 GTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTV 413
Query: 432 KENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEM-- 489
++ AT N V V I TS R + SS+ +S + S M
Sbjct: 414 PSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMET 473
Query: 490 ---GAPTVVVQQQQ---------QQQQQQQQQPALQGV-TLQQMDFGSTGPQSIPAVSIP 536
P+V VQ Q P V T++Q + P S
Sbjct: 474 RSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTG 533
Query: 537 QSISQS-QISQVQLQSQELSYQQK-QGLQPVPL-----QATMSAATGIQPSPVNVVGVTS 589
++ + ++ +QL + + S+ + QG+QP P+ Q GIQP+P+ G+ S
Sbjct: 534 VGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHS 593
Query: 590 AL-----GQQPSISSLAQPQLPYSQAAP-----------PVQTPLPGAPPPQQLQYGQQQ 633
A G QP+ QPQ +A P+ P AP
Sbjct: 594 ATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAP----------- 642
Query: 634 PMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIP-----VAQ 688
+T + H +S + N ++ +P ++ +P++ G+ T+IP VA
Sbjct: 643 --AATTVVQTHSQSASTNAPAQGSSPRP----SILRKKPATDGMAVRKTLIPPQPPDVAS 696
Query: 689 PQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQ 748
P+ ++ ++ T+ +PAGA +P + +++ T S Q + PT P+ Q
Sbjct: 697 PR-VESSMRSTSGSPRPAGA--KPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQ 753
Query: 749 VP----PSVIQQGAPPSS-----QVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTV 799
P P++I +PPS +P A I + T A + P + + S +
Sbjct: 754 QPPPTIPTMIAAASPPSQPAVALSTIPGAVP--ITPPITTIAAAPPPSVTVGGSLSSVLG 811
Query: 800 PPQP-----QGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPP 854
PP P + VEP+ +P +++ + S+++ + S S +P + P
Sbjct: 812 PPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKP 871
Query: 855 QNIAQTPATQNGNLVQSVS 873
+ +T+ G+++++ S
Sbjct: 872 RKQQHVISTEEGDMMETNS 890
Score = 48.1 bits (113), Expect = 4e-05
Identities = 94/425 (22%), Positives = 157/425 (36%), Gaps = 53/425 (12%)
Query: 563 QPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAP 622
QP+ + ++ + I P+ V V T A Q P I++ A + + P + P +
Sbjct: 271 QPIQSRPPVTTSNAIPPAVVATVSATRA--QSPVITTTAAHATDSALSRPTLSIQHPPSA 328
Query: 623 PPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTT 682
+ Q + + + P H T + Q +T S+G P +A T
Sbjct: 329 AISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQ----KTIFSTGTPVAA-----AT 379
Query: 683 VIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAA---VSAVPTGSQIANIGQQANIP 739
V P+ + +P+ SV QAP + VP+ S A +NIP
Sbjct: 380 VAPI---------LATNTIPSATTAGSVSHT-QAPTSTIVTMTVPSHSSHATAVTTSNIP 429
Query: 740 TA--VQQPSTQVPPSVIQQGAPPSSQVVP-----PAQTGIIHQGVQTSAPSLPQQLVIAS 792
A V Q T P + S ++P + + + + PS+P Q
Sbjct: 430 VAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQF---- 485
Query: 793 QSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSS---TGPSGMPSAPT 849
Q L T PP P+A P SS+ + V++Q + T +G+ A T
Sbjct: 486 QYFLPTYPP---SAYPLA---AHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVAST 539
Query: 850 NLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQSL-AQAIGS 908
+ P + A+ + +Q + QP I+T Q P+ + L Q I S
Sbjct: 540 VHLNPMQLMTVDAS-HARHIQGI-QPAPISTQG----IQPAPIGTPGIQPAPLGTQGIHS 593
Query: 909 QIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPLTTPLVDGE 968
+ +P+ +G Q G SAV +++ A+ P P T +V
Sbjct: 594 ATPINTQGLQPAPMGTQQ--PQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTH 651
Query: 969 DESSS 973
+S+S
Sbjct: 652 SQSAS 656
Score = 36.2 bits (82), Expect = 0.17
Identities = 33/136 (24%), Positives = 53/136 (38%), Gaps = 9/136 (6%)
Query: 5 PESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPPPSLL 64
PE +A AD A +A+P P + + + + +NA + P PS+L
Sbjct: 614 PEGKTSAVVLAD-GATIVANPISNPF-SAAPAATTVVQTHSQSASTNAPAQGSSPRPSIL 671
Query: 65 QPPPPA-----ASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPA 119
+ P + PQPP S + S + + P G K KS ++ TP
Sbjct: 672 RKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGA--KPKSEIHVSMATPV 729
Query: 120 QISASISSNNSIAEDT 135
+S SN + + T
Sbjct: 730 TVSMETVSNQNNDQPT 745
Score = 35.8 bits (81), Expect = 0.22
Identities = 68/315 (21%), Positives = 109/315 (34%), Gaps = 48/315 (15%)
Query: 608 SQAAPPVQTPLPG-APPPQQL----QYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPI 662
SQ P + P G + P Q+ G P + G V+ A E++
Sbjct: 29 SQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVS---AREHMSSSSS 85
Query: 663 LQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSA 722
LQ+ +P V+ PQ L A P + P PA +
Sbjct: 86 LQSREEKQEP----------VVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLS 135
Query: 723 VPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAP 782
G P PS + P APPS+ +PP G + +++S P
Sbjct: 136 FSEGLM--------KPPPKPTMPSRPIAP------APPSTLSLPPKVPGQVTVTMESSIP 181
Query: 783 ---SLPQQLVIASQSS------LLTVPPQPQGVEPVAQG----IVSQQLPAVSSLPSA-S 828
++P + Q ++T Q + A G I + LP ++ + S
Sbjct: 182 QASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMS 241
Query: 829 SISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQ 888
S VT+ + T S +P+A T Q+I P + S + PP + + AQ
Sbjct: 242 SSKVTTVLRPT--SQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQ 299
Query: 889 QIPLSSTQFSAQSLA 903
+++T A A
Sbjct: 300 SPVITTTAAHATDSA 314
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 80.5 bits (197), Expect = 8e-15
Identities = 105/383 (27%), Positives = 139/383 (36%), Gaps = 48/383 (12%)
Query: 497 QQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSY 556
QQQQQQQ QQQQQ ALQ QQ Q A QS Q Q V Q Q+L
Sbjct: 162 QQQQQQQFQQQQQAALQQQQQQQQQ------QQFQA---QQSAMQQQFQAVVQQQQQLQQ 212
Query: 557 QQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQT 616
QQ+Q + L Q + + QQ Q Q QA PP+Q
Sbjct: 213 QQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ 272
Query: 617 P--LPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQP-- 672
P PPP Q Q Q M TQ H + Q Q QP S QP
Sbjct: 273 PPMQQPQPPPSQALPQQLQQMHHTQ----HHQPPPQPQQPPVAQNQPSQLPPQSQTQPLV 328
Query: 673 SSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANI 732
S A G + + ++ P+ P QP Q Q A V G Q++
Sbjct: 329 SQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVS-- 386
Query: 733 GQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIAS 792
Q+++P + PS Q PP P Q +S P+ S
Sbjct: 387 --QSSLP-MLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPA-------PS 436
Query: 793 QSSLLTVP-PQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNL 851
SS L P PQP +Q V+ + P S+P S GP P P+++
Sbjct: 437 PSSFLPSPSPQP------SQSPVTARTPQNFSVP------------SPGPLNTPVNPSSV 478
Query: 852 VPPQNIAQTPATQNGNLVQSVSQ 874
+ P +Q Q + ++ +S+
Sbjct: 479 MSPAGSSQAEEQQYLDKLKQLSK 501
Score = 78.6 bits (192), Expect = 3e-14
Identities = 94/303 (31%), Positives = 118/303 (38%), Gaps = 55/303 (18%)
Query: 495 VVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQEL 554
VVQQQQQ QQQQQQQ L + Q Q + Q I+Q Q+ Q Q Q Q+
Sbjct: 203 VVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQL------QRIAQLQLQQQQQQQQQQ 256
Query: 555 SYQQKQGLQPVP--LQATMSAATGIQPSPVNVVGVTSALGQQ-PSISSLAQPQLPYSQAA 611
QQ+Q LQ P Q M QP P + AL QQ + Q P
Sbjct: 257 QQQQQQALQAQPPIQQPPMQQP---QPPP------SQALPQQLQQMHHTQHHQPPPQPQQ 307
Query: 612 PPVQTPLPGAPPPQQLQYGQQQPMVS-TQMAPGHV-------------KSVTQNPASEYV 657
PPV P PPQ Q QP+VS Q PG + V Q P V
Sbjct: 308 PPVAQNQPSQLPPQ----SQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQV 363
Query: 658 QQQPILQTAMSSGQPSSAGVGAGTTVIP----------VAQPQGIQLPVQPTAVPAQPAG 707
QQQ + Q + GV + +P V PQ + P QP+ P QP+
Sbjct: 364 QQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSS 423
Query: 708 ASVQPV--GQAPAAVSAVPTGSQIANIGQQANIPTAVQQPST-QVP-PSVIQQGAPPSSQ 763
V G AP+ S +P+ S Q + P + P VP P + PSS
Sbjct: 424 QPNSNVSSGPAPSPSSFLPSPSP-----QPSQSPVTARTPQNFSVPSPGPLNTPVNPSSV 478
Query: 764 VVP 766
+ P
Sbjct: 479 MSP 481
Score = 36.2 bits (82), Expect = 0.17
Identities = 47/207 (22%), Positives = 70/207 (33%), Gaps = 21/207 (10%)
Query: 29 PRRGSGS--GSASALNAAGTGVGSNATSSEDFPPPSLLQPPPPAASSTSGPQPPPP---- 82
P RG G G +L A G + + S + P S + P A ST+ PQ
Sbjct: 102 PPRGPGQSLGGMGSLGAMGQPM---SLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQV 158
Query: 83 --QSLNLLSQAQLQAQPLAPGGTQMKKKSGFQIT-SVTPAQISASISSNNSIAEDTESYD 139
Q Q Q Q Q Q +++ FQ S Q A + + + +
Sbjct: 159 ALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQ 218
Query: 140 DLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQP 199
L + H ++ + L R L ++ ++ Q+ QP + QP
Sbjct: 219 HLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQP 278
Query: 200 HLP---HLPQQNVVINGNAHPHHLHHH 223
P LPQQ HH HH
Sbjct: 279 QPPPSQALPQQ------LQQMHHTQHH 299
Score = 34.3 bits (77), Expect = 0.65
Identities = 59/274 (21%), Positives = 92/274 (33%), Gaps = 20/274 (7%)
Query: 651 NPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQG----IQLPVQPTAVPAQPA 706
N S+ P+ +G P++ G G Q G + QP ++ QP
Sbjct: 71 NKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPP 130
Query: 707 GASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVP 766
+ + A VS +Q+ + Q A QQ Q + +QQ Q
Sbjct: 131 PGTSGMAPHSMAVVSTATPQTQL-QLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQF 189
Query: 767 PAQTGIIHQGVQT---------SAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQ 817
AQ + Q Q Q L+ + + Q Q ++ +AQ + QQ
Sbjct: 190 QAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQ 249
Query: 818 LPAVSSLPSASSISVTSQVS-STGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPP 876
++ +Q P P P + PQ + Q TQ+ QPP
Sbjct: 250 QQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPP 309
Query: 877 LIATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQI 910
+A N Q+P S S AQA+ Q+
Sbjct: 310 -VAQNQ----PSQLPPQSQTQPLVSQAQALPGQM 338
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 76.3 bits (186), Expect = 1e-13
Identities = 113/466 (24%), Positives = 166/466 (35%), Gaps = 85/466 (18%)
Query: 449 ETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQ 508
ETVK++ +V E S S+ S E+ + T + + + + +
Sbjct: 73 ETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGE 132
Query: 509 QPALQGVTLQQMDFGSTGPQSI--------PAVSIPQ---SISQSQISQVQLQSQELSYQ 557
+ V D GS+ P+ I P++ PQ S S S Q LQ+Q + Q
Sbjct: 133 SSDSRSVN----DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQ 188
Query: 558 QKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLP-------YSQA 610
G+ P P A P P G + + QPQ P + Q
Sbjct: 189 APTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQ 248
Query: 611 APPV--QTPLPGAPPPQQLQYGQQQPMVST---QMAPGHVKSVTQNPASEYVQQQPILQT 665
AP + Q P PPP + QP+ + AP H QP L
Sbjct: 249 APALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA--------------QPPLH- 293
Query: 666 AMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPT 725
G P + AG P+ Q G P QP +P Q A P+G +PAA
Sbjct: 294 --GQGPPGPHSLQAG----PLLQHPG---PPQPFGLPPQ-ASQGQAPLGTSPAA------ 337
Query: 726 GSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLP 785
A T++Q P++Q S +Q PP Q +PPA + H P+ P
Sbjct: 338 ----------AYPHTSLQLPASQ---SALQSQQPPREQPLPPAPLAMPH---IKPPPTTP 381
Query: 786 QQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMP 845
+ A Q+ PP G P + ++LP ++ S +S+ P
Sbjct: 382 IPQLPAPQAH--KHPPHLSGPSPFSMN---------ANLPPPPALKPLSSLSTHHPPSAH 430
Query: 846 SAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIP 891
P L+P + Q L QS + PP A++ L Q P
Sbjct: 431 PPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAP 476
Score = 38.5 bits (88), Expect = 0.034
Identities = 43/158 (27%), Positives = 64/158 (40%), Gaps = 19/158 (12%)
Query: 751 PSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVP----PQPQGV 806
P I Q +S +P Q ++ + S QQ ++ +Q L P P P
Sbjct: 147 PKDIDQDNRSTSPSIPSPQDN------ESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA 200
Query: 807 EPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNG 866
P + QLP PSA+++ +++ P APT VP +I Q PA +
Sbjct: 201 PPG-----TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL-HP 254
Query: 867 NLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQSLAQ 904
S PP + + P Q + S+ Q SA S AQ
Sbjct: 255 QRPPSPHPPPHPSPH---PPLQPLTGSAGQPSAPSHAQ 289
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 76.3 bits (186), Expect = 1e-13
Identities = 113/466 (24%), Positives = 166/466 (35%), Gaps = 85/466 (18%)
Query: 449 ETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQ 508
ETVK++ +V E S S+ S E+ + T + + + + +
Sbjct: 627 ETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGE 686
Query: 509 QPALQGVTLQQMDFGSTGPQSI--------PAVSIPQ---SISQSQISQVQLQSQELSYQ 557
+ V D GS+ P+ I P++ PQ S S S Q LQ+Q + Q
Sbjct: 687 SSDSRSVN----DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQ 742
Query: 558 QKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLP-------YSQA 610
G+ P P A P P G + + QPQ P + Q
Sbjct: 743 APTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQ 802
Query: 611 APPV--QTPLPGAPPPQQLQYGQQQPMVST---QMAPGHVKSVTQNPASEYVQQQPILQT 665
AP + Q P PPP + QP+ + AP H QP L
Sbjct: 803 APALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA--------------QPPLH- 847
Query: 666 AMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPT 725
G P + AG P+ Q G P QP +P Q A P+G +PAA
Sbjct: 848 --GQGPPGPHSLQAG----PLLQHPG---PPQPFGLPPQ-ASQGQAPLGTSPAA------ 891
Query: 726 GSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLP 785
A T++Q P++Q S +Q PP Q +PPA + H P+ P
Sbjct: 892 ----------AYPHTSLQLPASQ---SALQSQQPPREQPLPPAPLAMPH---IKPPPTTP 935
Query: 786 QQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMP 845
+ A Q+ PP G P + ++LP ++ S +S+ P
Sbjct: 936 IPQLPAPQAH--KHPPHLSGPSPFSMN---------ANLPPPPALKPLSSLSTHHPPSAH 984
Query: 846 SAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIP 891
P L+P + Q L QS + PP A++ L Q P
Sbjct: 985 PPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAP 1030
Score = 38.5 bits (88), Expect = 0.034
Identities = 43/158 (27%), Positives = 64/158 (40%), Gaps = 19/158 (12%)
Query: 751 PSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVP----PQPQGV 806
P I Q +S +P Q ++ + S QQ ++ +Q L P P P
Sbjct: 701 PKDIDQDNRSTSPSIPSPQDN------ESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA 754
Query: 807 EPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNG 866
P + QLP PSA+++ +++ P APT VP +I Q PA +
Sbjct: 755 PPG-----TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL-HP 808
Query: 867 NLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQSLAQ 904
S PP + + P Q + S+ Q SA S AQ
Sbjct: 809 QRPPSPHPPPHPSPH---PPLQPLTGSAGQPSAPSHAQ 843
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 76.3 bits (186), Expect = 1e-13
Identities = 113/466 (24%), Positives = 166/466 (35%), Gaps = 85/466 (18%)
Query: 449 ETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQ 508
ETVK++ +V E S S+ S E+ + T + + + + +
Sbjct: 627 ETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGE 686
Query: 509 QPALQGVTLQQMDFGSTGPQSI--------PAVSIPQ---SISQSQISQVQLQSQELSYQ 557
+ V D GS+ P+ I P++ PQ S S S Q LQ+Q + Q
Sbjct: 687 SSDSRSVN----DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQ 742
Query: 558 QKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLP-------YSQA 610
G+ P P A P P G + + QPQ P + Q
Sbjct: 743 APTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQ 802
Query: 611 APPV--QTPLPGAPPPQQLQYGQQQPMVST---QMAPGHVKSVTQNPASEYVQQQPILQT 665
AP + Q P PPP + QP+ + AP H QP L
Sbjct: 803 APALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA--------------QPPLH- 847
Query: 666 AMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPT 725
G P + AG P+ Q G P QP +P Q A P+G +PAA
Sbjct: 848 --GQGPPGPHSLQAG----PLLQHPG---PPQPFGLPPQ-ASQGQAPLGTSPAA------ 891
Query: 726 GSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLP 785
A T++Q P++Q S +Q PP Q +PPA + H P+ P
Sbjct: 892 ----------AYPHTSLQLPASQ---SALQSQQPPREQPLPPAPLAMPH---IKPPPTTP 935
Query: 786 QQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMP 845
+ A Q+ PP G P + ++LP ++ S +S+ P
Sbjct: 936 IPQLPAPQAH--KHPPHLSGPSPFSMN---------ANLPPPPALKPLSSLSTHHPPSAH 984
Query: 846 SAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIP 891
P L+P + Q L QS + PP A++ L Q P
Sbjct: 985 PPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAP 1030
Score = 38.5 bits (88), Expect = 0.034
Identities = 43/158 (27%), Positives = 64/158 (40%), Gaps = 19/158 (12%)
Query: 751 PSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVP----PQPQGV 806
P I Q +S +P Q ++ + S QQ ++ +Q L P P P
Sbjct: 701 PKDIDQDNRSTSPSIPSPQDN------ESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA 754
Query: 807 EPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNG 866
P + QLP PSA+++ +++ P APT VP +I Q PA +
Sbjct: 755 PPG-----TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL-HP 808
Query: 867 NLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQSLAQ 904
S PP + + P Q + S+ Q SA S AQ
Sbjct: 809 QRPPSPHPPPHPSPH---PPLQPLTGSAGQPSAPSHAQ 843
>gi|162951884 R3H domain containing 2 [Homo sapiens]
Length = 976
Score = 74.3 bits (181), Expect = 6e-13
Identities = 114/439 (25%), Positives = 159/439 (36%), Gaps = 34/439 (7%)
Query: 462 RESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQ---------QQQQQQQQQQQPAL 512
R + GSS S +S ++G+ E+ Q QQQQQQQQQQ PAL
Sbjct: 358 RGDSIGSSKGGSAGRISRPGMALGAPEVCNQVTSSQSVRGLLPCTAQQQQQQQQQQLPAL 417
Query: 513 QGVTLQQMDFGSTGPQSIPAVSIP-QSISQSQISQVQLQSQELSYQQKQGLQPVPLQATM 571
QQ + +S P +S S+ + + Q + P Q +
Sbjct: 418 PPTPQQQPPLNNHMISQADDLSNPFGQMSLSRQGSTEAADPSAALFQTPLISQHPQQTSF 477
Query: 572 SAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQ 631
A+ QP P + +S P + PQ Y Q PP Q + PP Q Q
Sbjct: 478 IMASTGQPLPTSNYSTSS---HAPPTQQVLPPQ-GYMQ--PPQQIQVSYYPPGQYPNSNQ 531
Query: 632 QQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQG 691
Q +S +A S + QQP LQ M + Q + A +I V QPQ
Sbjct: 532 QYRPLSHPVA----YSPQRGQQLPQPSQQPGLQPMMPNQQQA-----AYQGMIGVQQPQN 582
Query: 692 I-QLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVP 750
L Q +++ Q G VQ P VP GS N+ Q + S V
Sbjct: 583 QGLLSSQRSSMGGQMQGLVVQ---YTPLPSYQVPVGSDSQNVVQPPFQQPMLVPVSQSVQ 639
Query: 751 PSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQ---GVE 807
+ G P ++PPAQ V P +Q + S + P PQ GV
Sbjct: 640 GGLPAAGVPVYYSMIPPAQQNGTSPSVGFLQPPGSEQYQMPQSPSPCSPPQMPQQYSGVS 699
Query: 808 PVAQGIVSQQL--PAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQN 865
P G+V QL P P S+ S P +L P + Q +
Sbjct: 700 PSGPGVVVMQLNVPNGPQPPQNPSMVQWSHCKYYSMDQRGQKPGDLYSPDSSPQANTQMS 759
Query: 866 GNLVQSVSQPPLIATNTNL 884
+ V S +Q P + T+L
Sbjct: 760 SSPVTSPTQSPAPSPVTSL 778
Score = 35.4 bits (80), Expect = 0.29
Identities = 56/213 (26%), Positives = 78/213 (36%), Gaps = 43/213 (20%)
Query: 496 VQQQQQQ----QQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQS 551
VQQ Q Q Q+ +QG+ +Q S +P S Q++ Q Q L
Sbjct: 577 VQQPQNQGLLSSQRSSMGGQMQGLVVQYTPLPS---YQVPVGSDSQNVVQPPFQQPMLVP 633
Query: 552 QELSYQQKQGLQPVPLQATM---SAATGIQPSPVNVVGVTSALGQQP-SISSLAQPQLP- 606
S Q VP+ +M + G PS + S Q P S S + PQ+P
Sbjct: 634 VSQSVQGGLPAAGVPVYYSMIPPAQQNGTSPSVGFLQPPGSEQYQMPQSPSPCSPPQMPQ 693
Query: 607 -YSQAAPP------VQTPLPGAPPPQQL---------------QYGQQ---------QPM 635
YS +P +Q +P P P Q Q GQ+ P
Sbjct: 694 QYSGVSPSGPGVVVMQLNVPNGPQPPQNPSMVQWSHCKYYSMDQRGQKPGDLYSPDSSPQ 753
Query: 636 VSTQMAPGHVKSVTQNPASEYVQQQPILQTAMS 668
+TQM+ V S TQ+PA V + T +S
Sbjct: 754 ANTQMSSSPVTSPTQSPAPSPVTSLSSVCTGLS 786
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 73.6 bits (179), Expect = 1e-12
Identities = 132/538 (24%), Positives = 202/538 (37%), Gaps = 88/538 (16%)
Query: 382 PNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTE-FYEKENAVPATE 440
P + T + S+Q+ P + S + + S ++ ++ + + F + NA+ A
Sbjct: 108 PGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVS 167
Query: 441 GVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQ 500
V +NK NP ++ S+ E++ + + V E G P +++
Sbjct: 168 SV-VNKF------NPFDLISDSEASQEETTKK---------QKVVQKEQGKPEGIIKPPL 211
Query: 501 QQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQ 560
QQQ + P QG G + P+SIS Q +++ Q + Q
Sbjct: 212 QQQPPKPI-PKQQG----------PGRDPLQQDGTPKSISSQQPEKIKSQPPGTG-KPIQ 259
Query: 561 GLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPG 620
G P T A +Q + + + S+ +P LP S + PP+Q P PG
Sbjct: 260 G--PTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV----KPSLP-SPSKPPIQQPTPG 312
Query: 621 APPPQQLQYGQQQPMVSTQMA------------PGHVKSVTQNPASEYVQQQPI---LQT 665
PP QQ + + QP + A PG VK Q P + QP+
Sbjct: 313 KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP 372
Query: 666 AMSSG--QPSSAGVGAGTTVIPVAQPQGI-QLPVQ---PTAVPAQPAGASVQPVGQAPAA 719
A +G +PSS G +AQP G+ + P Q P P Q G + +P+ Q P
Sbjct: 373 AQQTGSEKPSSEQPGPKA----LAQPPGVGKTPAQQPGPAKPPTQQVG-TPKPLAQQPGL 427
Query: 720 VSAVPTGSQIANIGQQANIPTAVQQPSTQVPP--SVIQQGAP--PSSQVVPPAQTGIIHQ 775
S QQ P + P+ Q P + QQ P P SQ+ PA+
Sbjct: 428 QSPAKAPGPTKTPVQQ---PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP 484
Query: 776 GVQTSAPSLPQQLVIASQSSLLTVPP--QPQGVEPVAQGIVSQQLPAVSSLPSASSISVT 833
G P P SQ T PP QP +P S Q P + PS
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKP------SPQQPGSTKPPS------- 531
Query: 834 SQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIP 891
Q S PS +P P + P +Q G+ QPP ++ + P +Q +P
Sbjct: 532 QQPGSAKPSAQQPSPAK--PSAQQSTKPVSQTGS--GKPLQPPTVSPSAKQPPSQGLP 585
Score = 48.9 bits (115), Expect = 3e-05
Identities = 157/748 (20%), Positives = 244/748 (32%), Gaps = 108/748 (14%)
Query: 49 GSNATSSEDFPPPSLLQPP--PPAASSTSGPQPPPPQSLN----LLSQAQLQAQPLAPGG 102
GS SSE P +L QPP + GP PP Q + L Q LQ+ APG
Sbjct: 377 GSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGP 436
Query: 103 TQMKKKSGFQITSVTPAQISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRA 162
T+ + P +I A + + T L
Sbjct: 437 TKT------PVQQPGPGKIPAQQAGPGKTS----------AQQTGPTKPPSQLPGPAKPP 480
Query: 163 TDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHH 222
P + ++ + ++ PG+ P P P P P PQQ G+ P
Sbjct: 481 PQQPGPAKPPPQQPGSAKPPSQQPGSTKP-PPQQPGPAKPS-PQQ----PGSTKP----- 529
Query: 223 HHQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITP--VAPTS-A 279
Q G PS + A + + PVS+ TGS + P V+P++
Sbjct: 530 -------PSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ----TGSGKPLQPPTVSPSAKQ 578
Query: 280 VSSSGSPASVMTNMRAPSTTGGIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNIS 339
S G P ++ + + T T + ++ FNPN + +
Sbjct: 579 PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCL 638
Query: 340 TSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQ 399
+ A G + P V + + +++++AVS S Q QQ
Sbjct: 639 NCQMKRALGGDLAP-----VPSSPQPKLKTAPVTTTSAVS------------KSSPQPQQ 681
Query: 400 PTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVT 459
+ L + EP K + A + + + + V
Sbjct: 682 TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVP 741
Query: 460 SERESTS-GSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQ 518
SE++ + T+ V S + + Q Q +++ P L+ + +
Sbjct: 742 SEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAK 801
Query: 519 -QMDFGSTGPQSIP--AVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAAT 575
F TG + P + +IP+ S S+I S E S QKQ + A T
Sbjct: 802 PSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSE-SKGQKQVDPVQKKEEPKKAQT 860
Query: 576 GIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQ-----LQYG 630
+ P P +P P P A V TP P +Q L G
Sbjct: 861 KMSPKP----------DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLG 910
Query: 631 ------QQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVI 684
+ QP + G + AS + Q ++ TA G S +G GA
Sbjct: 911 SITDAPKSQPTTPQETVTGKLFGF---GASIFSQASNLISTAGQPGPHSQSGPGAPMKQA 967
Query: 685 PV-AQPQGIQLPVQPT--AVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTA 741
P +QP Q P + T A PA V+ +APAA P Q PT
Sbjct: 968 PAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQ---------APTV 1018
Query: 742 VQQPSTQVPPSVIQQ---GAPPSSQVVP 766
+ + + PP + A P V+P
Sbjct: 1019 KRTETEKKPPPIKDSKSLTAEPQKAVLP 1046
Score = 45.8 bits (107), Expect = 2e-04
Identities = 126/685 (18%), Positives = 240/685 (35%), Gaps = 63/685 (9%)
Query: 253 PPSSPVSRKLS-TTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTGGIGINSVTGTS 311
P +P+ ++ +T D + + TS+V S S +T+ + S T I +T
Sbjct: 2082 PTQAPIGEDMTESTMDFDRMPDASLTSSVLSGAS----LTDSTS-SATLSIPDVKITQHF 2136
Query: 312 TVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGT 371
+ + V + + + I T + PS + SV P T + ++ S +
Sbjct: 2137 STEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDS 2196
Query: 372 ISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSE-PFKKGRWTCTEFY 430
S + S+ + + +++ F +D E R +
Sbjct: 2197 SSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGR 2256
Query: 431 EKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMG 490
+ + + + + ++E+V P ++ ST + S + + G+G
Sbjct: 2257 ASADHIVISLSDMASSIIESVVPKPEGPVADTVSTD--LLISEKDPVKKAKKETGNG--- 2311
Query: 491 APTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQ 550
++++ + + +++ + +L + F P S+ A+ + + Q+S
Sbjct: 2312 ---IILEVLEAYRDKKELEAERTKSSLSETVFDHP-PSSVIALPMKE-----QLSTTYFT 2362
Query: 551 SQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQA 610
S E Q+K Q +P + ++ +P P + S+ AQP P
Sbjct: 2363 SGETFGQEKPASQ-LPSGSPSVSSLPAKPRP---------FFRSSSLDISAQPPPPPPPP 2412
Query: 611 APPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSG 670
PP P P PPP + ++ + T P + V S+G
Sbjct: 2413 PPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG 2472
Query: 671 QPSSAGVGAGTTVIPVAQPQGIQLP--------VQPTAVPAQPAGASVQ--PVGQAPAAV 720
P + TT P P+ +P +P+ P P Q Q P +
Sbjct: 2473 LPVTR---ICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDI 2529
Query: 721 SAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTS 780
PTG + + N+ T+ PS +P S++ P + V +
Sbjct: 2530 HPKPTGLSLTS-SMTLNLVTSADYKL----PSPTSPLSPHSNKSSPRFSKSLTETYVVIT 2584
Query: 781 APSLPQQLVIASQSSLLTVPPQPQ------GVEP---VAQGIVSQQLPAVS--SLPSASS 829
PS P +S S +T P VEP V + + ++P S + + +
Sbjct: 2585 LPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGA 2644
Query: 830 ISVTSQVSSTGPSGMPSAPTNLVP--PQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLA 887
+ S T PS +APT++ +++T + + SV + T PLA
Sbjct: 2645 LQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLA 2704
Query: 888 -QQIPLSSTQFSAQSLAQAIGSQIE 911
I L Q+ Q +G I+
Sbjct: 2705 LDNIHLEKPQYKEDGKLQLVGDVID 2729
Score = 45.4 bits (106), Expect = 3e-04
Identities = 103/455 (22%), Positives = 154/455 (33%), Gaps = 104/455 (22%)
Query: 498 QQQQQQQQQQQQPALQGVTLQQMDFGST-----GPQSIPA--VSIPQSISQSQ--ISQVQ 548
QQ ++ +QP + + Q G T GP P V P+ ++Q S +
Sbjct: 374 QQTGSEKPSSEQPGPKALA-QPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK 432
Query: 549 LQSQELSYQQKQGLQPVPLQA-----TMSAATGIQPSPVNVVGVTSALGQQPSISSLAQP 603
+ Q+ G +P Q T + TG P + G QQP + P
Sbjct: 433 APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK-PPP 491
Query: 604 QLPYSQAAPPVQTPLPGAPPPQQ---LQYGQQQPMVST--QMAPGHVKSVTQ--NPASEY 656
Q P S A PP Q P PPPQQ + QQP + PG K Q +PA
Sbjct: 492 QQPGS-AKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550
Query: 657 VQQ--QPILQTAM-----------SSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTA--- 700
QQ +P+ QT S+ QP S G+ T+ P+ + L V A
Sbjct: 551 AQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK--TICPLCNTTELLLHVPEKANFN 608
Query: 701 --------------------------------------------VPAQPAGA-SVQPVGQ 715
VP+ P PV
Sbjct: 609 TCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTT 668
Query: 716 APAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQ----GAPPSSQVVPPAQTG 771
A + P Q + A + P + PP +++Q G+P + PP
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS 728
Query: 772 IIHQGVQTSAPSLPQQLVIASQSSLLTV----PPQPQGVEPVAQGIVSQQLPAVSSLPSA 827
+ S P+ P++ + S+ V P QP+ V+P + S +PS
Sbjct: 729 L-------SKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS- 780
Query: 828 SSISVTSQVSSTGPSGMPSA-PTNLVPPQNIAQTP 861
S + ++ +T P SA P+ PP +P
Sbjct: 781 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP 815
Score = 36.2 bits (82), Expect = 0.17
Identities = 82/403 (20%), Positives = 143/403 (35%), Gaps = 44/403 (10%)
Query: 457 EVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVT 516
E S +S + +S +SH S S V ++++ ++ Q + P
Sbjct: 811 EKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKP 870
Query: 517 LQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQ-----QKQGLQPVPLQATM 571
+ + GP+ ++P + Q + Q QS+ S QP Q T+
Sbjct: 871 MPKGSPTPPGPRPTAGQTVP---TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETV 927
Query: 572 SAAT-GIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYG 630
+ G S + + QP S + P P QA P Q P PP G
Sbjct: 928 TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKST---G 984
Query: 631 QQQPMVSTQMAPGHVKSVTQNPASEYV----QQQPILQTAMSSGQPSSAGVGAGTTVIPV 686
Q P + + VK T+ PA+E + +Q P ++ + +P T P
Sbjct: 985 QAPPAPAKSIP---VKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP- 1040
Query: 687 AQPQGIQLPVQPTAVPAQPAGASVQPVGQA---------PAAVSAVPTGSQIANIGQQAN 737
Q V PT + P S P+ + P + +Q+ N+
Sbjct: 1041 ------QKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNP 1094
Query: 738 IP--TAVQQ---PSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIAS 792
P T +Q+ + Q ++ G + +PPA +G + S Q+ +
Sbjct: 1095 TPHLTEIQEWLCLNCQTQRAI--SGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPP 1152
Query: 793 QSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQ 835
Q L V Q Q V+ A+ ++ +++ S+ + T Q
Sbjct: 1153 QVKL--VKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ 1193
Score = 32.7 bits (73), Expect = 1.9
Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 1028 KTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGP 1071
K A P L + AQ Q G+ QP GTT+PPAQP P
Sbjct: 330 KPPAQPSGLTKPLAQ-QPGTVKPPVQPPGTTKPPAQPLGPAKPP 372
Score = 32.3 bits (72), Expect = 2.5
Identities = 120/565 (21%), Positives = 198/565 (35%), Gaps = 103/565 (18%)
Query: 33 SGSGSASALNAAGTGVGSNAT---SSEDFPPPSLLQPPPPAASSTSGPQPPPPQSLNLLS 89
SGS S S+L A +++ S++ PPP PPPP P PPPP L
Sbjct: 2378 SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP------PPPPPPPPL---- 2427
Query: 90 QAQLQAQPLAPGGTQMKKKSGFQITSVTPAQISASISSNNSIAEDTESYDDLDESHTEDL 149
P +P T + KK ++T +P + T +D + T +
Sbjct: 2428 -----PPPTSPKPTILPKK---KLTVASP------------VTTATPLFDAVTTLETTAV 2467
Query: 150 SSSEILDVS-LSRATDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPHLPQQN 208
S L V+ + P + SS + F P P P+P +P LP
Sbjct: 2468 LRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPS----KPPIAPKPVIPQLP--- 2520
Query: 209 VVINGNAHPHHLHHHHQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPVS--RKLSTTG 266
P +H G L + V SA P+SP+S S+
Sbjct: 2521 ---TTTQKPTDIHPKPT---GLSLTSS---MTLNLVTSADYKLPSPTSPLSPHSNKSSPR 2571
Query: 267 SSDSIT--------PVAPTSAVSSSGSPASVMTNMRAPS--TTGGIGINSVTGTSTVNNV 316
S S+T P P + SS S A + +PS + SV T +
Sbjct: 2572 FSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEI 2631
Query: 317 NITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGN-----GT 371
I++ +F + ++ + AA SV +T+ V+ +S + G
Sbjct: 2632 PISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGL 2691
Query: 372 ISSSAAVSSVPNAAAGM--------------TGGSVSSQQQQPTVNT-SRFRVVKLDSSS 416
S S + P A + G V + P V + + + L +S+
Sbjct: 2692 SSISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSAST 2751
Query: 417 EPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVST 476
K+ + T E Y K+ + A + +IN V + P+ + +E + + S+S +T
Sbjct: 2752 MDVKR-QITANEVYGKQ--ISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTT 2808
Query: 477 LSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQ---------------GVTLQQMD 521
TES+ E T + + + + P+ Q G +
Sbjct: 2809 ---GTESLVGAEHAMTTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVT 2865
Query: 522 FGSTGPQSIPAVSIPQSISQSQISQ 546
T P ++P V + + S +SQ
Sbjct: 2866 LAITKPVTVPPVGVTNGWTDSTVSQ 2890
Score = 31.6 bits (70), Expect = 4.2
Identities = 29/110 (26%), Positives = 39/110 (35%), Gaps = 13/110 (11%)
Query: 3 QPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPP-- 60
QP + A A + + P P + +G G SA T S PP
Sbjct: 424 QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQ 483
Query: 61 PSLLQPPP--PAASSTSGPQP----PPPQSLNLLSQAQLQAQPLAPGGTQ 104
P +PPP P ++ QP PPPQ + P PG T+
Sbjct: 484 PGPAKPPPQQPGSAKPPSQQPGSTKPPPQ-----QPGPAKPSPQQPGSTK 528
Score = 31.6 bits (70), Expect = 4.2
Identities = 43/187 (22%), Positives = 79/187 (42%), Gaps = 26/187 (13%)
Query: 502 QQQQQQQQPALQGVT-----LQQMDFGSTGPQSIPA---VSIPQSISQSQISQ-----VQ 548
++++++++ LQGV + + ST P I + + P++ Q++ SQ Q
Sbjct: 3814 KEREKRERAYLQGVAEDRDYMSDSEVSSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQ 3873
Query: 549 LQSQELS----YQQKQGLQP-VPLQATMSAATGIQPSPVNVVGV-TSALGQQPSISSLAQ 602
+SQ + Y Q Q P +P QA S + S QP+ ++A
Sbjct: 3874 TESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVAT 3933
Query: 603 PQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPI 662
+ ++ P TP P P Q+ QQ+P +T +T N E ++ QP+
Sbjct: 3934 --MSFTPQVQPTPTPQPSYQLPSQMMVIQQKPRQTTLYLE---PKITSN--YEVIRNQPL 3986
Query: 663 LQTAMSS 669
+ +S+
Sbjct: 3987 MIAPVST 3993
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 73.6 bits (179), Expect = 1e-12
Identities = 132/538 (24%), Positives = 202/538 (37%), Gaps = 88/538 (16%)
Query: 382 PNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTE-FYEKENAVPATE 440
P + T + S+Q+ P + S + + S ++ ++ + + F + NA+ A
Sbjct: 108 PGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVS 167
Query: 441 GVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQ 500
V +NK NP ++ S+ E++ + + V E G P +++
Sbjct: 168 SV-VNKF------NPFDLISDSEASQEETTKK---------QKVVQKEQGKPEGIIKPPL 211
Query: 501 QQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQ 560
QQQ + P QG G + P+SIS Q +++ Q + Q
Sbjct: 212 QQQPPKPI-PKQQG----------PGRDPLQQDGTPKSISSQQPEKIKSQPPGTG-KPIQ 259
Query: 561 GLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPG 620
G P T A +Q + + + S+ +P LP S + PP+Q P PG
Sbjct: 260 G--PTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV----KPSLP-SPSKPPIQQPTPG 312
Query: 621 APPPQQLQYGQQQPMVSTQMA------------PGHVKSVTQNPASEYVQQQPI---LQT 665
PP QQ + + QP + A PG VK Q P + QP+
Sbjct: 313 KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP 372
Query: 666 AMSSG--QPSSAGVGAGTTVIPVAQPQGI-QLPVQ---PTAVPAQPAGASVQPVGQAPAA 719
A +G +PSS G +AQP G+ + P Q P P Q G + +P+ Q P
Sbjct: 373 AQQTGSEKPSSEQPGPKA----LAQPPGVGKTPAQQPGPAKPPTQQVG-TPKPLAQQPGL 427
Query: 720 VSAVPTGSQIANIGQQANIPTAVQQPSTQVPP--SVIQQGAP--PSSQVVPPAQTGIIHQ 775
S QQ P + P+ Q P + QQ P P SQ+ PA+
Sbjct: 428 QSPAKAPGPTKTPVQQ---PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP 484
Query: 776 GVQTSAPSLPQQLVIASQSSLLTVPP--QPQGVEPVAQGIVSQQLPAVSSLPSASSISVT 833
G P P SQ T PP QP +P S Q P + PS
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKP------SPQQPGSTKPPS------- 531
Query: 834 SQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIP 891
Q S PS +P P + P +Q G+ QPP ++ + P +Q +P
Sbjct: 532 QQPGSAKPSAQQPSPAK--PSAQQSTKPVSQTGS--GKPLQPPTVSPSAKQPPSQGLP 585
Score = 48.9 bits (115), Expect = 3e-05
Identities = 157/748 (20%), Positives = 244/748 (32%), Gaps = 108/748 (14%)
Query: 49 GSNATSSEDFPPPSLLQPP--PPAASSTSGPQPPPPQSLN----LLSQAQLQAQPLAPGG 102
GS SSE P +L QPP + GP PP Q + L Q LQ+ APG
Sbjct: 377 GSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGP 436
Query: 103 TQMKKKSGFQITSVTPAQISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRA 162
T+ + P +I A + + T L
Sbjct: 437 TKT------PVQQPGPGKIPAQQAGPGKTS----------AQQTGPTKPPSQLPGPAKPP 480
Query: 163 TDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHH 222
P + ++ + ++ PG+ P P P P P PQQ G+ P
Sbjct: 481 PQQPGPAKPPPQQPGSAKPPSQQPGSTKP-PPQQPGPAKPS-PQQ----PGSTKP----- 529
Query: 223 HHQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITP--VAPTS-A 279
Q G PS + A + + PVS+ TGS + P V+P++
Sbjct: 530 -------PSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ----TGSGKPLQPPTVSPSAKQ 578
Query: 280 VSSSGSPASVMTNMRAPSTTGGIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNIS 339
S G P ++ + + T T + ++ FNPN + +
Sbjct: 579 PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCL 638
Query: 340 TSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQ 399
+ A G + P V + + +++++AVS S Q QQ
Sbjct: 639 NCQMKRALGGDLAP-----VPSSPQPKLKTAPVTTTSAVS------------KSSPQPQQ 681
Query: 400 PTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVT 459
+ L + EP K + A + + + + V
Sbjct: 682 TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVP 741
Query: 460 SERESTS-GSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQ 518
SE++ + T+ V S + + Q Q +++ P L+ + +
Sbjct: 742 SEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAK 801
Query: 519 -QMDFGSTGPQSIP--AVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAAT 575
F TG + P + +IP+ S S+I S E S QKQ + A T
Sbjct: 802 PSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSE-SKGQKQVDPVQKKEEPKKAQT 860
Query: 576 GIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQ-----LQYG 630
+ P P +P P P A V TP P +Q L G
Sbjct: 861 KMSPKP----------DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLG 910
Query: 631 ------QQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVI 684
+ QP + G + AS + Q ++ TA G S +G GA
Sbjct: 911 SITDAPKSQPTTPQETVTGKLFGF---GASIFSQASNLISTAGQPGPHSQSGPGAPMKQA 967
Query: 685 PV-AQPQGIQLPVQPT--AVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTA 741
P +QP Q P + T A PA V+ +APAA P Q PT
Sbjct: 968 PAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQ---------APTV 1018
Query: 742 VQQPSTQVPPSVIQQ---GAPPSSQVVP 766
+ + + PP + A P V+P
Sbjct: 1019 KRTETEKKPPPIKDSKSLTAEPQKAVLP 1046
Score = 45.8 bits (107), Expect = 2e-04
Identities = 126/685 (18%), Positives = 240/685 (35%), Gaps = 63/685 (9%)
Query: 253 PPSSPVSRKLS-TTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTGGIGINSVTGTS 311
P +P+ ++ +T D + + TS+V S S +T+ + S T I +T
Sbjct: 2082 PTQAPIGEDMTESTMDFDRMPDASLTSSVLSGAS----LTDSTS-SATLSIPDVKITQHF 2136
Query: 312 TVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGT 371
+ + V + + + I T + PS + SV P T + ++ S +
Sbjct: 2137 STEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDS 2196
Query: 372 ISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSE-PFKKGRWTCTEFY 430
S + S+ + + +++ F +D E R +
Sbjct: 2197 SSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGR 2256
Query: 431 EKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMG 490
+ + + + + ++E+V P ++ ST + S + + G+G
Sbjct: 2257 ASADHIVISLSDMASSIIESVVPKPEGPVADTVSTD--LLISEKDPVKKAKKETGNG--- 2311
Query: 491 APTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQ 550
++++ + + +++ + +L + F P S+ A+ + + Q+S
Sbjct: 2312 ---IILEVLEAYRDKKELEAERTKSSLSETVFDHP-PSSVIALPMKE-----QLSTTYFT 2362
Query: 551 SQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQA 610
S E Q+K Q +P + ++ +P P + S+ AQP P
Sbjct: 2363 SGETFGQEKPASQ-LPSGSPSVSSLPAKPRP---------FFRSSSLDISAQPPPPPPPP 2412
Query: 611 APPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSG 670
PP P P PPP + ++ + T P + V S+G
Sbjct: 2413 PPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG 2472
Query: 671 QPSSAGVGAGTTVIPVAQPQGIQLP--------VQPTAVPAQPAGASVQ--PVGQAPAAV 720
P + TT P P+ +P +P+ P P Q Q P +
Sbjct: 2473 LPVTR---ICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDI 2529
Query: 721 SAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTS 780
PTG + + N+ T+ PS +P S++ P + V +
Sbjct: 2530 HPKPTGLSLTS-SMTLNLVTSADYKL----PSPTSPLSPHSNKSSPRFSKSLTETYVVIT 2584
Query: 781 APSLPQQLVIASQSSLLTVPPQPQ------GVEP---VAQGIVSQQLPAVS--SLPSASS 829
PS P +S S +T P VEP V + + ++P S + + +
Sbjct: 2585 LPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGA 2644
Query: 830 ISVTSQVSSTGPSGMPSAPTNLVP--PQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLA 887
+ S T PS +APT++ +++T + + SV + T PLA
Sbjct: 2645 LQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLA 2704
Query: 888 -QQIPLSSTQFSAQSLAQAIGSQIE 911
I L Q+ Q +G I+
Sbjct: 2705 LDNIHLEKPQYKEDGKLQLVGDVID 2729
Score = 45.4 bits (106), Expect = 3e-04
Identities = 103/455 (22%), Positives = 154/455 (33%), Gaps = 104/455 (22%)
Query: 498 QQQQQQQQQQQQPALQGVTLQQMDFGST-----GPQSIPA--VSIPQSISQSQ--ISQVQ 548
QQ ++ +QP + + Q G T GP P V P+ ++Q S +
Sbjct: 374 QQTGSEKPSSEQPGPKALA-QPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK 432
Query: 549 LQSQELSYQQKQGLQPVPLQA-----TMSAATGIQPSPVNVVGVTSALGQQPSISSLAQP 603
+ Q+ G +P Q T + TG P + G QQP + P
Sbjct: 433 APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK-PPP 491
Query: 604 QLPYSQAAPPVQTPLPGAPPPQQ---LQYGQQQPMVST--QMAPGHVKSVTQ--NPASEY 656
Q P S A PP Q P PPPQQ + QQP + PG K Q +PA
Sbjct: 492 QQPGS-AKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550
Query: 657 VQQ--QPILQTAM-----------SSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTA--- 700
QQ +P+ QT S+ QP S G+ T+ P+ + L V A
Sbjct: 551 AQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK--TICPLCNTTELLLHVPEKANFN 608
Query: 701 --------------------------------------------VPAQPAGA-SVQPVGQ 715
VP+ P PV
Sbjct: 609 TCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTT 668
Query: 716 APAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQ----GAPPSSQVVPPAQTG 771
A + P Q + A + P + PP +++Q G+P + PP
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS 728
Query: 772 IIHQGVQTSAPSLPQQLVIASQSSLLTV----PPQPQGVEPVAQGIVSQQLPAVSSLPSA 827
+ S P+ P++ + S+ V P QP+ V+P + S +PS
Sbjct: 729 L-------SKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS- 780
Query: 828 SSISVTSQVSSTGPSGMPSA-PTNLVPPQNIAQTP 861
S + ++ +T P SA P+ PP +P
Sbjct: 781 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP 815
Score = 36.2 bits (82), Expect = 0.17
Identities = 82/403 (20%), Positives = 143/403 (35%), Gaps = 44/403 (10%)
Query: 457 EVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVT 516
E S +S + +S +SH S S V ++++ ++ Q + P
Sbjct: 811 EKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKP 870
Query: 517 LQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQ-----QKQGLQPVPLQATM 571
+ + GP+ ++P + Q + Q QS+ S QP Q T+
Sbjct: 871 MPKGSPTPPGPRPTAGQTVP---TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETV 927
Query: 572 SAAT-GIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYG 630
+ G S + + QP S + P P QA P Q P PP G
Sbjct: 928 TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKST---G 984
Query: 631 QQQPMVSTQMAPGHVKSVTQNPASEYV----QQQPILQTAMSSGQPSSAGVGAGTTVIPV 686
Q P + + VK T+ PA+E + +Q P ++ + +P T P
Sbjct: 985 QAPPAPAKSIP---VKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP- 1040
Query: 687 AQPQGIQLPVQPTAVPAQPAGASVQPVGQA---------PAAVSAVPTGSQIANIGQQAN 737
Q V PT + P S P+ + P + +Q+ N+
Sbjct: 1041 ------QKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNP 1094
Query: 738 IP--TAVQQ---PSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIAS 792
P T +Q+ + Q ++ G + +PPA +G + S Q+ +
Sbjct: 1095 TPHLTEIQEWLCLNCQTQRAI--SGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPP 1152
Query: 793 QSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQ 835
Q L V Q Q V+ A+ ++ +++ S+ + T Q
Sbjct: 1153 QVKL--VKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ 1193
Score = 32.7 bits (73), Expect = 1.9
Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 1028 KTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGP 1071
K A P L + AQ Q G+ QP GTT+PPAQP P
Sbjct: 330 KPPAQPSGLTKPLAQ-QPGTVKPPVQPPGTTKPPAQPLGPAKPP 372
Score = 32.3 bits (72), Expect = 2.5
Identities = 120/565 (21%), Positives = 198/565 (35%), Gaps = 103/565 (18%)
Query: 33 SGSGSASALNAAGTGVGSNAT---SSEDFPPPSLLQPPPPAASSTSGPQPPPPQSLNLLS 89
SGS S S+L A +++ S++ PPP PPPP P PPPP L
Sbjct: 2378 SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP------PPPPPPPPL---- 2427
Query: 90 QAQLQAQPLAPGGTQMKKKSGFQITSVTPAQISASISSNNSIAEDTESYDDLDESHTEDL 149
P +P T + KK ++T +P + T +D + T +
Sbjct: 2428 -----PPPTSPKPTILPKK---KLTVASP------------VTTATPLFDAVTTLETTAV 2467
Query: 150 SSSEILDVS-LSRATDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPHLPQQN 208
S L V+ + P + SS + F P P P+P +P LP
Sbjct: 2468 LRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPS----KPPIAPKPVIPQLP--- 2520
Query: 209 VVINGNAHPHHLHHHHQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPVS--RKLSTTG 266
P +H G L + V SA P+SP+S S+
Sbjct: 2521 ---TTTQKPTDIHPKPT---GLSLTSS---MTLNLVTSADYKLPSPTSPLSPHSNKSSPR 2571
Query: 267 SSDSIT--------PVAPTSAVSSSGSPASVMTNMRAPS--TTGGIGINSVTGTSTVNNV 316
S S+T P P + SS S A + +PS + SV T +
Sbjct: 2572 FSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEI 2631
Query: 317 NITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGN-----GT 371
I++ +F + ++ + AA SV +T+ V+ +S + G
Sbjct: 2632 PISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGL 2691
Query: 372 ISSSAAVSSVPNAAAGM--------------TGGSVSSQQQQPTVNT-SRFRVVKLDSSS 416
S S + P A + G V + P V + + + L +S+
Sbjct: 2692 SSISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSAST 2751
Query: 417 EPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVST 476
K+ + T E Y K+ + A + +IN V + P+ + +E + + S+S +T
Sbjct: 2752 MDVKR-QITANEVYGKQ--ISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTT 2808
Query: 477 LSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQ---------------GVTLQQMD 521
TES+ E T + + + + P+ Q G +
Sbjct: 2809 ---GTESLVGAEHAMTTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVT 2865
Query: 522 FGSTGPQSIPAVSIPQSISQSQISQ 546
T P ++P V + + S +SQ
Sbjct: 2866 LAITKPVTVPPVGVTNGWTDSTVSQ 2890
Score = 31.6 bits (70), Expect = 4.2
Identities = 29/110 (26%), Positives = 39/110 (35%), Gaps = 13/110 (11%)
Query: 3 QPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPP-- 60
QP + A A + + P P + +G G SA T S PP
Sbjct: 424 QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQ 483
Query: 61 PSLLQPPP--PAASSTSGPQP----PPPQSLNLLSQAQLQAQPLAPGGTQ 104
P +PPP P ++ QP PPPQ + P PG T+
Sbjct: 484 PGPAKPPPQQPGSAKPPSQQPGSTKPPPQ-----QPGPAKPSPQQPGSTK 528
Score = 31.6 bits (70), Expect = 4.2
Identities = 43/187 (22%), Positives = 79/187 (42%), Gaps = 26/187 (13%)
Query: 502 QQQQQQQQPALQGVT-----LQQMDFGSTGPQSIPA---VSIPQSISQSQISQ-----VQ 548
++++++++ LQGV + + ST P I + + P++ Q++ SQ Q
Sbjct: 3814 KEREKRERAYLQGVAEDRDYMSDSEVSSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQ 3873
Query: 549 LQSQELS----YQQKQGLQP-VPLQATMSAATGIQPSPVNVVGV-TSALGQQPSISSLAQ 602
+SQ + Y Q Q P +P QA S + S QP+ ++A
Sbjct: 3874 TESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVAT 3933
Query: 603 PQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPI 662
+ ++ P TP P P Q+ QQ+P +T +T N E ++ QP+
Sbjct: 3934 --MSFTPQVQPTPTPQPSYQLPSQMMVIQQKPRQTTLYLE---PKITSN--YEVIRNQPL 3986
Query: 663 LQTAMSS 669
+ +S+
Sbjct: 3987 MIAPVST 3993
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 73.2 bits (178), Expect = 1e-12
Identities = 102/370 (27%), Positives = 136/370 (36%), Gaps = 47/370 (12%)
Query: 497 QQQQQQQQQQQQQPAL-QGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQV--QLQSQE 553
Q QQ QQQ P L + V Q GP+ +P+V P+SIS S + + L+S
Sbjct: 1982 QWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPR-MPSVQPPRSISPSALQDLLRTLKSPS 2040
Query: 554 LSYQQKQGLQPVPLQATMSAA-------------TGIQPSPVNVVGVTSALGQQPSISSL 600
QQ+Q L + + AA G+QP P G+ S G QP
Sbjct: 2041 SPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQP----GLQSQPGMQPQPGMH 2096
Query: 601 AQPQLPYSQAAPPVQTPLPGAPPPQQLQYG-QQQPMVSTQMAPGH----------VKSVT 649
QP L + A P PG PP QQ G Q M PGH + +
Sbjct: 2097 QQPSL-QNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREML 2155
Query: 650 QNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVI-PVAQPQGIQLPVQPTAVPAQPAGA 708
+ + QQQ Q Q SAG+ G QPQG P A+ Q
Sbjct: 2156 RRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQG--PGGYPPAMQQQQRMQ 2213
Query: 709 SVQPVGQAPAAVSAVPTGSQIANIGQQA-------NIPTAVQQPSTQVPPSVIQQGAPPS 761
P+ + A G Q+ +GQ NI A+QQ Q Q G+P
Sbjct: 2214 QHLPLQGSSMGQMAAQMG-QLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQ 2272
Query: 762 SQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAV 821
+ P Q + Q A LP Q + S S+ + P Q P +Q S P +
Sbjct: 2273 PNPMSPQQHML---SGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRI 2329
Query: 822 SSLPSASSIS 831
PS +S
Sbjct: 2330 QPQPSPHHVS 2339
Score = 65.5 bits (158), Expect = 3e-10
Identities = 213/1023 (20%), Positives = 345/1023 (33%), Gaps = 219/1023 (21%)
Query: 187 GAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHH------GHHLQHGHHHPS 240
G++ + LP +P+ + ++ +GN P H Q+ G + G + S
Sbjct: 31 GSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVS 90
Query: 241 HVAVASASITG---GPPSSPVSRKLSTTGSS-----DSITPVAPTSAVSSSGSPASVMTN 292
+ + G G P+S LS G S DS P P A S+SG P +
Sbjct: 91 ASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSG-PTPAASQ 149
Query: 293 MRAPSTTGGIGI------NSVTGTSTVNNVNI--TAVGSFNPNVTSSMLGNVNISTSNI- 343
P +G+ S TG N N T G N N S++ + + +
Sbjct: 150 ALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVM 209
Query: 344 -------------------PSAAGVS----------VGPGVT--SGVNVNILSGMGNGTI 372
P+ G S V P +T +G+N GM I
Sbjct: 210 NGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGI 269
Query: 373 SSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWT----CTE 428
+ + + P + AG G + + P + + + V L + K T ++
Sbjct: 270 TGNTSPFGQPFSQAG--GQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQ 327
Query: 429 FYEKENAVPATEGVLINKVVETVKQNPIEVT----------SERESTSGSSVSSSV---- 474
VP T+ + + K+ I+ RE +G + S+
Sbjct: 328 MQTSVGIVP-TQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCR 386
Query: 475 ---STLSHYTESVGSGE----MGAPTVVVQQQ------QQQQQQQQQQPALQGVTLQQMD 521
+ L+H T +G+P +Q QQ P + Q
Sbjct: 387 TMKNVLNHMTHCQAGKACQAILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRA 446
Query: 522 FGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGI--QP 579
+ + G +P ++ PQ+ Q Q+ Q +Q ++QQ + L P+ A GI
Sbjct: 447 YAALG---LPYMNQPQTQLQPQVPGQQ-PAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ 502
Query: 580 SPVNVV---------GVTSALGQQPSISSLAQPQLPYSQAAPP----------------- 613
P N++ G T+ L S S AAPP
Sbjct: 503 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL 562
Query: 614 --------VQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYV-------- 657
VQ P P P L+ + + +V+ + N EY
Sbjct: 563 RSHLVHKLVQAIFP-TPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIY 621
Query: 658 ---------QQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQ---- 704
++ + + + QP+ GA VIP AQP ++ P P ++P
Sbjct: 622 KIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQP--VRPPNGPLSLPVNRMQV 679
Query: 705 --------PAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQV-PPSVI- 754
P + QAP A + + ++P PS PP+++
Sbjct: 680 SQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMG 739
Query: 755 ------QQGAPPSSQVVP------------------PAQTGIIHQGVQTSAPSLPQQL-V 789
AP SQ +P PAQTG+ QG Q +LP L +
Sbjct: 740 AHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGV-SQG-QVPGAALPNPLNM 797
Query: 790 IASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGM----P 845
+ Q+S L PP Q P + P AS+ + + T P GM P
Sbjct: 798 LGPQASQLPCPPVTQS-------------PLHPTPPPASTAAGMPSLQHTTPPGMTPPQP 844
Query: 846 SAPTN-LVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQSLAQ 904
+APT P + QTP G+ V S +Q T AQ P T S+A
Sbjct: 845 AAPTQPSTPVSSSGQTPTPTPGS-VPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVAT 903
Query: 905 AIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPLTTPL 964
SQ + A+P L Q + + S +S+ + + VL + T
Sbjct: 904 PQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTET 963
Query: 965 VDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYA--VREEVEVL--KEQIKELIEKNSQL 1020
+ E G ++K E ++++ L A V+EE ++ K + E+ EK ++
Sbjct: 964 QAEDTEPDPG------ESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEV 1017
Query: 1021 EQE 1023
+ E
Sbjct: 1018 KVE 1020
Score = 55.8 bits (133), Expect = 2e-07
Identities = 61/252 (24%), Positives = 99/252 (39%), Gaps = 13/252 (5%)
Query: 437 PATEGVLINKVVETVKQNPIEVTSERESTSGSS-VSSSVSTLSHYTESVGSGEMGAPTVV 495
P +L ++++ +Q + +++ GS+ ++ ++ + + G G G P +
Sbjct: 2149 PQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPG--GYPPAM 2206
Query: 496 VQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELS 555
QQQ+ QQ Q ++ + Q G G + A S P Q + Q LQ Q++
Sbjct: 2207 QQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPN--IQQALQQRILQQQQMK 2264
Query: 556 YQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQ 615
Q QP P+ +G QP ++ G A + S A Q P Q+ PP
Sbjct: 2265 QQIGSPGQPNPMSPQQHMLSG-QPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHS 2323
Query: 616 TPLP---GAPPPQQL--QYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSG 670
+P P P P + Q G P ++ MA + NP E P L T S
Sbjct: 2324 SPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNP--EQSAMLPQLNTPSRSA 2381
Query: 671 QPSSAGVGAGTT 682
S + TT
Sbjct: 2382 LSSELSLVGDTT 2393
Score = 52.4 bits (124), Expect = 2e-06
Identities = 99/416 (23%), Positives = 150/416 (36%), Gaps = 82/416 (19%)
Query: 461 ERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQM 520
+R++ G V + L Y + E P + + +QQQ Q LQ L +
Sbjct: 1771 KRKTNGGCPVCKQLIALCCY-HAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRR 1829
Query: 521 DFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPS 580
+ +++P S+P S + Q S Q QP P Q QPS
Sbjct: 1830 RMATMNTRNVPQQSLPSPTSAPPGTPTQQPS------TPQTPQP-PAQP--------QPS 1874
Query: 581 PVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQM 640
PV++ S G PS++ QP S P Q P P PPP Q
Sbjct: 1875 PVSM----SPAG-FPSVAR-TQPPTTVSTGKPTSQVPAP--PPP-------------AQP 1913
Query: 641 APGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGA-GTTVIPVA----QPQGIQLP 695
P V++ Q QQ +S P G+G G+ + PV+ +P + P
Sbjct: 1914 PPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGP 1973
Query: 696 VQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQ 755
V P+ P Q QQA +P QQP +P VI
Sbjct: 1974 VMPSMPPGQ----------------------------WQQAPLPQ--QQPMPGLPRPVIS 2003
Query: 756 QGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVS 815
A + V P + Q ++ +PS Q L+ +S P PQ + V + S
Sbjct: 2004 MQA--QAAVAGPRMPSV--QPPRSISPSALQDLLRTLKS-----PSSPQQQQQVLNILKS 2054
Query: 816 QQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQS 871
+ + ++ V +Q G+ S P + P + Q P+ QN N +Q+
Sbjct: 2055 NPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQP-GMQPQPGMHQQPSLQNLNAMQA 2109
Score = 46.6 bits (109), Expect = 1e-04
Identities = 106/450 (23%), Positives = 169/450 (37%), Gaps = 46/450 (10%)
Query: 625 QQLQYG-QQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTV 683
QQ+Q+ QQ ++ +MA + ++V Q P T QPS+ T
Sbjct: 1815 QQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQ----QPSTP-----QTP 1865
Query: 684 IPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQ 743
P AQPQ P+ V PAG Q P VS SQ+ A P A
Sbjct: 1866 QPPAQPQ-------PSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAV 1918
Query: 744 QPSTQVPPSVIQQG---APPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVP 800
+ + Q+ QQ + +PP +TG+ G Q + SL + +Q S +P
Sbjct: 1919 EAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSL--NVPRPNQVSGPVMP 1976
Query: 801 PQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQT 860
P G Q + QQ P + LP IS+ +Q + GP MPS + PP++I+ +
Sbjct: 1977 SMPPG--QWQQAPLPQQQP-MPGLP-RPVISMQAQAAVAGPR-MPS----VQPPRSISPS 2027
Query: 861 PATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPS 920
++S S P L + + P F Q A+ + +Q +P
Sbjct: 2028 ALQDLLRTLKSPSSPQ--QQQQVLNILKSNPQLMAAFIKQRTAKYVANQ---PGMQPQPG 2082
Query: 921 LVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPLTTPLVDGEDESSSGASVVAI 980
L P G S +L A + P +P + G + +++
Sbjct: 2083 LQSQP----GMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNP 2138
Query: 981 DNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQF- 1039
+ ++ + Y ++L++Q ++ ++ Q +Q+ QF
Sbjct: 2139 GHN----PNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQ 2194
Query: 1040 QAQLQTGSPPATTQPQGTTQP-PAQPASQG 1068
Q Q G PPA Q Q Q P Q +S G
Sbjct: 2195 QPQGPGGYPPAMQQQQRMQQHLPLQGSSMG 2224
Score = 37.7 bits (86), Expect = 0.059
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 32 GSGSGSASALNAAG-TGVGSNATSSEDFPPPSLLQPPPPAASSTSGPQPPPPQSLNLLSQ 90
G G ++ N A + +G + S D PSL P A+STSGP P Q+LN +Q
Sbjct: 101 GQAQGQPNSANMASLSAMGKSPLSQGDSSAPSL----PKQAASTSGPTPAASQALNPQAQ 156
Query: 91 AQLQAQPLAPGGTQ 104
Q+ +P +Q
Sbjct: 157 KQVGLATSSPATSQ 170
Score = 32.0 bits (71), Expect = 3.2
Identities = 40/193 (20%), Positives = 67/193 (34%), Gaps = 23/193 (11%)
Query: 4 PPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPPPSL 63
PP T AA + ++ P GS ++ + V + A + P +
Sbjct: 836 PPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTP 895
Query: 64 LQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQISA 123
+QPP A +S QP P + AQP PG + + TP+ +++
Sbjct: 896 VQPPSVATPQSSQQQPTP-----------VHAQP--PGTPLSQAAASIDNRVPTPSSVAS 942
Query: 124 SISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNFQEA 183
+ +++ D + E+ ED GEP EE L +
Sbjct: 943 AETNSQQPGPDVPVLEMKTETQAEDTEPDP--------GESKGEPRSEMMEEDLQGASQV 994
Query: 184 --ETPGAVSPNQP 194
ET A ++P
Sbjct: 995 KEETDIAEQKSEP 1007
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 73.2 bits (178), Expect = 1e-12
Identities = 102/370 (27%), Positives = 136/370 (36%), Gaps = 47/370 (12%)
Query: 497 QQQQQQQQQQQQQPAL-QGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQV--QLQSQE 553
Q QQ QQQ P L + V Q GP+ +P+V P+SIS S + + L+S
Sbjct: 2020 QWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPR-MPSVQPPRSISPSALQDLLRTLKSPS 2078
Query: 554 LSYQQKQGLQPVPLQATMSAA-------------TGIQPSPVNVVGVTSALGQQPSISSL 600
QQ+Q L + + AA G+QP P G+ S G QP
Sbjct: 2079 SPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQP----GLQSQPGMQPQPGMH 2134
Query: 601 AQPQLPYSQAAPPVQTPLPGAPPPQQLQYG-QQQPMVSTQMAPGH----------VKSVT 649
QP L + A P PG PP QQ G Q M PGH + +
Sbjct: 2135 QQPSL-QNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREML 2193
Query: 650 QNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVI-PVAQPQGIQLPVQPTAVPAQPAGA 708
+ + QQQ Q Q SAG+ G QPQG P A+ Q
Sbjct: 2194 RRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQG--PGGYPPAMQQQQRMQ 2251
Query: 709 SVQPVGQAPAAVSAVPTGSQIANIGQQA-------NIPTAVQQPSTQVPPSVIQQGAPPS 761
P+ + A G Q+ +GQ NI A+QQ Q Q G+P
Sbjct: 2252 QHLPLQGSSMGQMAAQMG-QLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQ 2310
Query: 762 SQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAV 821
+ P Q + Q A LP Q + S S+ + P Q P +Q S P +
Sbjct: 2311 PNPMSPQQHML---SGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRI 2367
Query: 822 SSLPSASSIS 831
PS +S
Sbjct: 2368 QPQPSPHHVS 2377
Score = 59.7 bits (143), Expect = 1e-08
Identities = 139/632 (21%), Positives = 225/632 (35%), Gaps = 102/632 (16%)
Query: 459 TSERESTSGSSVSS-SVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTL 517
T ++ +TS S+ + S++ ++G M P +Q Q QQ Q Q Q TL
Sbjct: 462 TGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTL 521
Query: 518 QQMDFGSTGPQSIPAVSI------PQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATM 571
+ P +IPA I P IS+S + + L G +
Sbjct: 522 NPL---GNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPL---MNDGSNSGNIGTLS 575
Query: 572 SAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQY-- 629
+ T PS V G ++ + L + TP P A ++++
Sbjct: 576 TIPTAAPPSSTGV-----RKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLV 630
Query: 630 -------GQQQPMVSTQMAPGHV---KSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGA 679
G +++ H+ K E ++ + + + QP+ GA
Sbjct: 631 AYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGA 690
Query: 680 GTTVIPVAQPQGIQLPVQPTAVPAQ------------PAGASVQPVGQAPAAVSAVPTGS 727
VIP AQP ++ P P ++P P + QAP A +
Sbjct: 691 QPPVIPQAQP--VRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMN 748
Query: 728 QIANIGQQANIPTAVQQPSTQV-PPSVI-------QQGAPPSSQVVP------------- 766
+ ++P PS PP+++ AP SQ +P
Sbjct: 749 HSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSV 808
Query: 767 -----PAQTGIIHQGVQTSAPSLPQQL-VIASQSSLLTVPPQPQGVEPVAQGIVSQQLPA 820
PAQTG+ QG Q +LP L ++ Q+S L PP Q P
Sbjct: 809 GMGQPPAQTGV-SQG-QVPGAALPNPLNMLGPQASQLPCPPVTQS-------------PL 853
Query: 821 VSSLPSASSISVTSQVSSTGPSGM----PSAPTN-LVPPQNIAQTPATQNGNLVQSVSQP 875
+ P AS+ + + T P GM P+APT P + QTP G+ V S +Q
Sbjct: 854 HPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGS-VPSATQT 912
Query: 876 PLIATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGM 935
T AQ P T S+A SQ + A+P L Q + +
Sbjct: 913 QSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRV 972
Query: 936 SAVSDGSSSSLAASASLFPLKVLPLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHL 995
S +S+ + + VL + T + E G ++K E ++++ L
Sbjct: 973 PTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPG------ESKGEPRSEMMEEDL 1026
Query: 996 MYA--VREEVEVL--KEQIKELIEKNSQLEQE 1023
A V+EE ++ K + E+ EK +++ E
Sbjct: 1027 QGASQVKEETDIAEQKSEPMEVDEKKPEVKVE 1058
Score = 55.8 bits (133), Expect = 2e-07
Identities = 61/252 (24%), Positives = 99/252 (39%), Gaps = 13/252 (5%)
Query: 437 PATEGVLINKVVETVKQNPIEVTSERESTSGSS-VSSSVSTLSHYTESVGSGEMGAPTVV 495
P +L ++++ +Q + +++ GS+ ++ ++ + + G G G P +
Sbjct: 2187 PQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPG--GYPPAM 2244
Query: 496 VQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELS 555
QQQ+ QQ Q ++ + Q G G + A S P Q + Q LQ Q++
Sbjct: 2245 QQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPN--IQQALQQRILQQQQMK 2302
Query: 556 YQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQ 615
Q QP P+ +G QP ++ G A + S A Q P Q+ PP
Sbjct: 2303 QQIGSPGQPNPMSPQQHMLSG-QPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHS 2361
Query: 616 TPLP---GAPPPQQL--QYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSG 670
+P P P P + Q G P ++ MA + NP E P L T S
Sbjct: 2362 SPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNP--EQSAMLPQLNTPSRSA 2419
Query: 671 QPSSAGVGAGTT 682
S + TT
Sbjct: 2420 LSSELSLVGDTT 2431
Score = 52.4 bits (124), Expect = 2e-06
Identities = 99/416 (23%), Positives = 150/416 (36%), Gaps = 82/416 (19%)
Query: 461 ERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQM 520
+R++ G V + L Y + E P + + +QQQ Q LQ L +
Sbjct: 1809 KRKTNGGCPVCKQLIALCCY-HAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRR 1867
Query: 521 DFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPS 580
+ +++P S+P S + Q S Q QP P Q QPS
Sbjct: 1868 RMATMNTRNVPQQSLPSPTSAPPGTPTQQPS------TPQTPQP-PAQP--------QPS 1912
Query: 581 PVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQM 640
PV++ S G PS++ QP S P Q P P PPP Q
Sbjct: 1913 PVSM----SPAG-FPSVAR-TQPPTTVSTGKPTSQVPAP--PPP-------------AQP 1951
Query: 641 APGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGA-GTTVIPVA----QPQGIQLP 695
P V++ Q QQ +S P G+G G+ + PV+ +P + P
Sbjct: 1952 PPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGP 2011
Query: 696 VQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQ 755
V P+ P Q QQA +P QQP +P VI
Sbjct: 2012 VMPSMPPGQ----------------------------WQQAPLPQ--QQPMPGLPRPVIS 2041
Query: 756 QGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVS 815
A + V P + Q ++ +PS Q L+ +S P PQ + V + S
Sbjct: 2042 MQA--QAAVAGPRMPSV--QPPRSISPSALQDLLRTLKS-----PSSPQQQQQVLNILKS 2092
Query: 816 QQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQS 871
+ + ++ V +Q G+ S P + P + Q P+ QN N +Q+
Sbjct: 2093 NPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQP-GMQPQPGMHQQPSLQNLNAMQA 2147
Score = 47.4 bits (111), Expect = 7e-05
Identities = 199/965 (20%), Positives = 323/965 (33%), Gaps = 174/965 (18%)
Query: 187 GAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHH------GHHLQHGHHHPS 240
G++ + LP +P+ + ++ +GN P H Q+ G + G + S
Sbjct: 31 GSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVS 90
Query: 241 HVAVASASITG---GPPSSPVSRKLSTTGSS-----DSITPVAPTSAVSSSGSPASVMTN 292
+ + G G P+S LS G S DS P P A S+SG P +
Sbjct: 91 ASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSG-PTPAASQ 149
Query: 293 MRAPSTTGGIGI------NSVTGTSTVNNVNI--TAVGSFNPNVTSSMLGNVNISTSNIP 344
P +G+ S TG N N T G N N S++ + + +
Sbjct: 150 ALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVM 209
Query: 345 SAAGVSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQP---- 400
+ + + G G +G+ + G SSS ++ + MTG + + Q
Sbjct: 210 NGSLGAAGRGRGAGMPYPTPAMQG---ASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAK 266
Query: 401 ---TVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIE 457
T NTS F + +P N A++ ++N + I+
Sbjct: 267 MGITGNTSPFGQPFSQAGGQPMGA---------TGVNPQLASKQSMVNSL--PTFPTDIK 315
Query: 458 VTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTV--VVQQQQ----QQQQQQQQQPA 511
TS + S + +SV + T+++ +G P ++QQQ + Q+++ A
Sbjct: 316 NTSVTNVPNMSQMQTSVGIVP--TQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQA 373
Query: 512 LQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATM 571
V + T + ++ Q+ Q++ Q +S+ + P+ +
Sbjct: 374 NGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPL 433
Query: 572 SAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYG- 630
A+ + + ++G + A G Q +I S+ Q Q A + P P P Q Y
Sbjct: 434 KNASD-KRNQQTILG-SPASGIQNTIGSVGTGQ----QNATSLSNPNPIDPSSMQRAYAA 487
Query: 631 -----QQQPMVSTQ-MAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVI 684
QP Q PG Q PA QQ ++T G + + AG
Sbjct: 488 LGLPYMNQPQTQLQPQVPG------QQPAQPQTHQQ--MRTLNPLGN-NPMNIPAGGITT 538
Query: 685 PVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQ 744
P I PT++ A P+ + GS NIG + IPTA
Sbjct: 539 DQQPPNLISESALPTSLGA------TNPL---------MNDGSNSGNIGTLSTIPTA--- 580
Query: 745 PSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSL-PQQLVIASQSSLLTVPPQP 803
PPS V ++ ++H+ VQ P+ P L +L+ +
Sbjct: 581 ----APPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKV 636
Query: 804 QG----------------VEPV----------------AQGIVSQQ--LPAVSSLPSASS 829
+G E + QGI+ Q LPA + P
Sbjct: 637 EGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPV-- 694
Query: 830 ISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQ 889
+ P P+ P +L P N Q N S P+ N LP A
Sbjct: 695 ------IPQAQPVRPPNGPLSL--PVNRMQVSQGMN-------SFNPMSLGNVQLPQAPM 739
Query: 890 IPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAAS 949
P +++ + ++GS P + P + M A ++ + A
Sbjct: 740 GPRAASPMNHSVQMNSMGS---------VPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQ 790
Query: 950 ASLFPLKVLPLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQ 1009
+ P P SSSGA V + Q A+ + +L Q
Sbjct: 791 SQFLPQNQFP-----------SSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQ 839
Query: 1010 IKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGSPPATT--QPQGTTQPPAQPASQ 1067
+L + L P A LQ +PP T QP TQP +S
Sbjct: 840 ASQL----PCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 895
Query: 1068 GSGPT 1072
G PT
Sbjct: 896 GQTPT 900
Score = 46.6 bits (109), Expect = 1e-04
Identities = 106/450 (23%), Positives = 169/450 (37%), Gaps = 46/450 (10%)
Query: 625 QQLQYG-QQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTV 683
QQ+Q+ QQ ++ +MA + ++V Q P T QPS+ T
Sbjct: 1853 QQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQ----QPSTP-----QTP 1903
Query: 684 IPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQ 743
P AQPQ P+ V PAG Q P VS SQ+ A P A
Sbjct: 1904 QPPAQPQ-------PSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAV 1956
Query: 744 QPSTQVPPSVIQQG---APPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVP 800
+ + Q+ QQ + +PP +TG+ G Q + SL + +Q S +P
Sbjct: 1957 EAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSL--NVPRPNQVSGPVMP 2014
Query: 801 PQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQT 860
P G Q + QQ P + LP IS+ +Q + GP MPS + PP++I+ +
Sbjct: 2015 SMPPG--QWQQAPLPQQQP-MPGLP-RPVISMQAQAAVAGPR-MPS----VQPPRSISPS 2065
Query: 861 PATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPS 920
++S S P L + + P F Q A+ + +Q +P
Sbjct: 2066 ALQDLLRTLKSPSSPQ--QQQQVLNILKSNPQLMAAFIKQRTAKYVANQ---PGMQPQPG 2120
Query: 921 LVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPLTTPLVDGEDESSSGASVVAI 980
L P G S +L A + P +P + G + +++
Sbjct: 2121 LQSQP----GMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNP 2176
Query: 981 DNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQF- 1039
+ ++ + Y ++L++Q ++ ++ Q +Q+ QF
Sbjct: 2177 GHN----PNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQ 2232
Query: 1040 QAQLQTGSPPATTQPQGTTQP-PAQPASQG 1068
Q Q G PPA Q Q Q P Q +S G
Sbjct: 2233 QPQGPGGYPPAMQQQQRMQQHLPLQGSSMG 2262
Score = 37.7 bits (86), Expect = 0.059
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 32 GSGSGSASALNAAG-TGVGSNATSSEDFPPPSLLQPPPPAASSTSGPQPPPPQSLNLLSQ 90
G G ++ N A + +G + S D PSL P A+STSGP P Q+LN +Q
Sbjct: 101 GQAQGQPNSANMASLSAMGKSPLSQGDSSAPSL----PKQAASTSGPTPAASQALNPQAQ 156
Query: 91 AQLQAQPLAPGGTQ 104
Q+ +P +Q
Sbjct: 157 KQVGLATSSPATSQ 170
Score = 35.0 bits (79), Expect = 0.38
Identities = 72/326 (22%), Positives = 107/326 (32%), Gaps = 53/326 (16%)
Query: 313 VNNVNIT-AVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNI-LSGMGN- 369
VN + ++ + SFNP LGNV + P A +GP S +N ++ ++ MG+
Sbjct: 712 VNRMQVSQGMNSFNP----MSLGNVQL-----PQAP---MGPRAASPMNHSVQMNSMGSV 759
Query: 370 -GTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTE 428
G S + + PN M G ++ Q + + SSS G
Sbjct: 760 PGMAISPSRMPQPPN----MMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGM----- 810
Query: 429 FYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGE 488
PA GV +V NP+ + + S + H T S
Sbjct: 811 -----GQPPAQTGVSQGQVPGAALPNPLNMLGPQASQL--PCPPVTQSPLHPTPPPASTA 863
Query: 489 MGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQ 548
G P++ Q QPA + P P S+P + VQ
Sbjct: 864 AGMPSL---QHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPG-SVPSATQTQSTPTVQ 919
Query: 549 LQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYS 608
+Q Q T T +QP V + QQP+ P P S
Sbjct: 920 AAAQA--------------QVTPQPQTPVQPPSV---ATPQSSQQQPTPVHAQPPGTPLS 962
Query: 609 QAAPPVQTPLPGAPPPQQLQYGQQQP 634
QAA + +P + QQP
Sbjct: 963 QAAASIDNRVPTPSSVASAETNSQQP 988
Score = 32.0 bits (71), Expect = 3.2
Identities = 40/193 (20%), Positives = 67/193 (34%), Gaps = 23/193 (11%)
Query: 4 PPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPPPSL 63
PP T AA + ++ P GS ++ + V + A + P +
Sbjct: 874 PPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTP 933
Query: 64 LQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQISA 123
+QPP A +S QP P + AQP PG + + TP+ +++
Sbjct: 934 VQPPSVATPQSSQQQPTP-----------VHAQP--PGTPLSQAAASIDNRVPTPSSVAS 980
Query: 124 SISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNFQEA 183
+ +++ D + E+ ED GEP EE L +
Sbjct: 981 AETNSQQPGPDVPVLEMKTETQAEDTEPDP--------GESKGEPRSEMMEEDLQGASQV 1032
Query: 184 --ETPGAVSPNQP 194
ET A ++P
Sbjct: 1033 KEETDIAEQKSEP 1045
>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
Length = 2382
Score = 72.0 bits (175), Expect = 3e-12
Identities = 146/606 (24%), Positives = 219/606 (36%), Gaps = 86/606 (14%)
Query: 452 KQNPIEVTSER--ESTSGSSVSSSVSTLSHYTESVGSG-EMGAPTVVVQQQQQQQQQQQQ 508
+Q I V S+ +S GSSV + S T S GS E T V Q Q
Sbjct: 643 QQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQS 702
Query: 509 QPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQL----QSQELSY-QQKQGLQ 563
QP GV P S+ Q SQ Q S L SQ + + QQ+QG+Q
Sbjct: 703 QP--HGV--------------YPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQ 746
Query: 564 PV-PLQATMS-----AATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTP 617
P Q T+ +T + + V A P +S A QLP SQ P +Q
Sbjct: 747 QTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVS--AGKQLPVSQPVPTIQ-- 802
Query: 618 LPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGV 677
G P Q+ Q P V + H V Q + + Q P+ Q +S+ S+A
Sbjct: 803 --GEP---QIPVATQ-PSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVSTAQT 856
Query: 678 GAGTTVIPVAQPQGIQLPVQPTAVPAQPA---GAS----------VQPVGQAPAAVS--- 721
G + +P+ GI P+ A A A G S +QPV Q P+ V
Sbjct: 857 GFSS--LPITMAAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQL 914
Query: 722 ---AVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQ 778
AV + AN+GQ A +P + Q P + P S + P + +
Sbjct: 915 LQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVCIHST 974
Query: 779 TSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSS 838
+P +P +++ V P + V G V Q+ S + TS +
Sbjct: 975 VLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTSSQQA 1034
Query: 839 TGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFS 898
S + P +AQT ATQ L SV + + +P SS +
Sbjct: 1035 VLESTQGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNENVPSSSGRHE 1094
Query: 899 AQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVL 958
++ + + R + S L + VS+ + K++
Sbjct: 1095 GRTTKRHYRKSVRSRSRHEKTSRPKL---------RILNVSNKGDRVVECQLETHNRKMV 1145
Query: 959 PLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNS 1018
L DG DN E A +V + + A+ E V +Q++E+IEK
Sbjct: 1146 TFKFDL-DG-------------DNPEEIATIMVNNDFILAIERESFV--DQVREIIEKAD 1189
Query: 1019 QLEQEN 1024
++ E+
Sbjct: 1190 EMLSED 1195
Score = 71.6 bits (174), Expect = 4e-12
Identities = 94/383 (24%), Positives = 149/383 (38%), Gaps = 51/383 (13%)
Query: 546 QVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQL 605
Q+ + QE Q++ L+ Q++ S TGI+ P G+ +A S+S+ +P+
Sbjct: 573 QLVREEQEKKKQEESSLKQQVEQSSASQ-TGIKQLPSASTGIPTASTTSASVSTQVEPEE 631
Query: 606 PYSQAAPPVQTPLPG----------------------APPPQQLQYGQQQPMV-STQMAP 642
P + +Q P Q + YG Q ST P
Sbjct: 632 PEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVP 691
Query: 643 GHVKSVTQNPASEY-VQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAV 701
GH+ S Q + + V + S GQPSS+ + ++ P+ PQ Q +Q TA
Sbjct: 692 GHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQ-QQGIQQTAP 750
Query: 702 PAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPS 761
P Q S+ + A +A P SQ + Q P +Q P++ QG P
Sbjct: 751 PQQTVQYSLSQTSTSSEATTAQPV-SQPQAPQVLPQVSAGKQLPVSQPVPTI--QGEP-- 805
Query: 762 SQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAV 821
Q+ Q ++ V + A LP + +P P P++ VS
Sbjct: 806 -QIPVATQPSVV--PVHSGAHFLP----VGQPLPTPLLPQYPVSQIPISTPHVSTAQTGF 858
Query: 822 SSLPSASSISVTSQV----SSTGPSGMPSAPTNLVPP------QNIAQTPATQNGNLVQS 871
SSLP + +T + SS + +P T +VP Q + Q P+ + L+Q
Sbjct: 859 SSLPITMAAGITQPLLTLASSATTAAIPGVST-VVPSQLPTLLQPVTQLPSQVHPQLLQP 917
Query: 872 VSQPPLIATNTNLPLAQQIPLSS 894
Q + NL A ++PLSS
Sbjct: 918 AVQS--MGIPANLGQAAEVPLSS 938
Score = 64.7 bits (156), Expect = 4e-10
Identities = 213/990 (21%), Positives = 349/990 (35%), Gaps = 191/990 (19%)
Query: 42 NAAGTGVGSNATSSEDFPPPSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPG 101
++ GT G ++ + P + PP A S QP SL +S +Q P
Sbjct: 685 HSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPSS-SSLTGVSSSQPIQHP---- 739
Query: 102 GTQMKKKSGFQITSVTPAQISASISSNNSIAEDTESYDDLDESHTEDL---SSSEILDVS 158
+++ G Q T+ + S+S ++ +E T + + L S+ + L VS
Sbjct: 740 ----QQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVS 795
Query: 159 LSRATDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPH 218
T GEP+ + T + + P LP P LP P + I+ PH
Sbjct: 796 QPVPTIQGEPQIPVA--TQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIPIST---PH 850
Query: 219 HLHHHHQIHHGHHLQHGHHHPSHVAVASASITGGPP--SSPVSRKLST-----TGSSDSI 271
+ +AS++ T P S+ V +L T T +
Sbjct: 851 VSTAQTGFSSLPITMAAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQV 910
Query: 272 TPVAPTSAVSSSGSPASVMTNMRAPSTTGGI--------------GINSVTGTSTVNNVN 317
P AV S G PA++ P ++G + G +++ +S V +V
Sbjct: 911 HPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSNVASVC 970
Query: 318 ITAV--------------GSF----NPNVTSSML-------GNVNIST-----SNIPSAA 347
I + G F P V S++L G V +S + P+ +
Sbjct: 971 IHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAPTTS 1030
Query: 348 GVSVGPGVTSGVN-------VNILSGMGNGTISSSAAVSSV-PNAAAGMTGG-----SVS 394
T GV+ V + + +++V S + A+GM+ G S S
Sbjct: 1031 SQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNENVPSSS 1090
Query: 395 SQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVK-- 452
+ + T + V+ S E + + K + V + N+ + T K
Sbjct: 1091 GRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFD 1150
Query: 453 ---QNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSG-EMGAPTVVVQQQQQQQQQQQQ 508
NP E+ + + S + E + EM + V V+ + Q +
Sbjct: 1151 LDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLE--- 1207
Query: 509 QPALQGVTLQQMDFGSTGPQS--------IPAVSIPQSIS--QSQISQVQLQSQEL---- 554
+LQG + D+G +G Q IPA S+PQ I S ++QV +
Sbjct: 1208 --SLQG----KDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVS 1261
Query: 555 ----SYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQL----- 605
S ++ + P + T++A+T P +N+ S+L Q + S L + Q+
Sbjct: 1262 PVPESRLRESKVFPSEITDTVAASTAQSPG-MNLSHSASSLSLQQAFSELRRAQMTEGPN 1320
Query: 606 ----------PYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASE 655
P PP + + G P P+ +T P + +
Sbjct: 1321 TAPPNFSHTGPTFPVVPPFLSSIAGVPTTA----AATAPVPATSSPPNDISTSVIQSEVT 1376
Query: 656 YVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQ 715
++ I A S+G +S G+ + PV++ + V +PA + ++ P Q
Sbjct: 1377 VPTEEGIAGVATSTGVVTSGGL----PIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQ 1432
Query: 716 APAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVP----PSVIQQGAPPSSQVVPPAQTG 771
P + S + S + +A ST P P+V+ Q A S+ V
Sbjct: 1433 VPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTV----GAT 1488
Query: 772 IIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSIS 831
+ TS PS QL I SS T P E V + SA S+
Sbjct: 1489 LTSVSTTTSFPSTASQLSIQLSSSTST----PTLAETV--------------VVSAHSLD 1530
Query: 832 VTSQVSSTGPSGMPSAPTN--------------------LVPPQNIAQTP-------ATQ 864
TS S+TG + SAP++ LV P IA TP T
Sbjct: 1531 KTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTS 1590
Query: 865 NGNLVQSVSQPPLIATNTNLPLAQQIPLSS 894
L Q S PPL+ N+P QQ + S
Sbjct: 1591 TPLLPQVPSIPPLVQPVANVPAVQQTLIHS 1620
Score = 53.1 bits (126), Expect = 1e-06
Identities = 140/665 (21%), Positives = 234/665 (35%), Gaps = 156/665 (23%)
Query: 247 ASITGGPPSSPVSRKLSTTGSSDSITPV-------APTSAVSSSGSPAS----------- 288
A +T GP ++P + S TG + + P PT+A +++ PA+
Sbjct: 1313 AQMTEGPNTAPPN--FSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSV 1370
Query: 289 VMTNMRAPSTTGGIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAG 348
+ + + P+ G G+ + TG T + I P V+ S + + +S+ IP+
Sbjct: 1371 IQSEVTVPTEEGIAGVATSTGVVTSGGLPI-------PPVSESPVLSSVVSSITIPAVVS 1423
Query: 349 VSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVP-NAAAGMTGGSVSSQQQQPTVNTSRF 407
+S T+ ++ + + +SS+A SV +A + GGS ++ +P S
Sbjct: 1424 IS-----TTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVS-- 1476
Query: 408 RVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSG 467
++ A T G + V T
Sbjct: 1477 ------------------------QQAAGSTTVGATLTSVSTT----------------- 1495
Query: 468 SSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGP 527
+S S+ S LS S S A TVVV + L +
Sbjct: 1496 TSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGL------AFSLSAPSS 1549
Query: 528 QSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGV 587
S P + IS Q GL P+ + + + A+T I P G
Sbjct: 1550 SSSPGAGVSSYIS-----------------QPGGLHPLVIPSVI-ASTPILP---QAAGP 1588
Query: 588 TSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQ-LQYGQQQPMVSTQMAPGHVK 646
TS P LP + PP+ P+ P QQ L + Q QP + H
Sbjct: 1589 TST------------PLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCP 1636
Query: 647 SVTQN--PASEYVQQQPILQTAMSS--GQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVP 702
V + P + + L+ + S + SS+G + + + L ++ T P
Sbjct: 1637 EVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETS------LVIESTVTP 1690
Query: 703 AQPAGASVQPVGQAPAAVSAV--PTGSQIANIGQQANIPTAVQQPSTQV--PPSVIQQGA 758
P A V P + S PT + + Q ST V S ++ G
Sbjct: 1691 GIPTTA-VAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGT 1749
Query: 759 PPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQP-QGVEPVAQGIVSQQ 817
PS P + ++ G + A +LP + + LT QP + ++ + +S +
Sbjct: 1750 APSKP--PLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPE 1807
Query: 818 LPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPL 877
+ I+VTS V GP M +APT + TQ V V + P+
Sbjct: 1808 M-----------ITVTSAV---GPVSM-AAPTAIT-------EAGTQPQKGVSQVKEGPV 1845
Query: 878 IATNT 882
+AT++
Sbjct: 1846 LATSS 1850
Score = 46.6 bits (109), Expect = 1e-04
Identities = 89/404 (22%), Positives = 140/404 (34%), Gaps = 67/404 (16%)
Query: 704 QPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQ 763
+ + AS + Q P+A + +PT S + A++ T V+ + Q PS
Sbjct: 594 EQSSASQTGIKQLPSASTGIPTASTTS-----ASVSTQVEPEEPEADQHQQLQYQQPSIS 648
Query: 764 VVPPAQTGIIHQGVQTSA-----PSLPQQLVIASQS----SLLTVP----------PQPQ 804
V+ G + G +S S Q + SQ S TVP QP
Sbjct: 649 VL---SDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPH 705
Query: 805 GVEP---VAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTP 861
GV P VAQG SQ P+ SSL SS S Q +AP +++QT
Sbjct: 706 GVYPPSSVAQG-QSQGQPSSSSLTGVSS-SQPIQHPQQQQGIQQTAPPQQTVQYSLSQTS 763
Query: 862 ATQNGNLVQSVSQP------PLIATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARR 915
+ Q VSQP P ++ LP++Q +P T + A +
Sbjct: 764 TSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVP---TIQGEPQIPVATQPSVVPVHS 820
Query: 916 AAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPLTTPLVDGEDESSSGA 975
A VG P +P+ +P++TP V S
Sbjct: 821 GAHFLPVGQPLP-------------------TPLLPQYPVSQIPISTPHVSTAQTGFSSL 861
Query: 976 SVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQE------NNLLKT 1029
+ + + L S A+ V+ Q+ L++ +QL + +++
Sbjct: 862 PITMAAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQS 921
Query: 1030 LASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGPTA 1073
+ P L Q A++ S Q PP P P++
Sbjct: 922 MGIPANLGQ-AAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSS 964
Score = 45.4 bits (106), Expect = 3e-04
Identities = 63/277 (22%), Positives = 102/277 (36%), Gaps = 24/277 (8%)
Query: 625 QQLQYGQQQPMVSTQMAPGHVKSVTQNPASEY-VQQQPILQTAMSSGQPSSAGVGAGTTV 683
+Q Q +++ Q + V Q+ AS+ ++Q P T + + +SA V
Sbjct: 570 EQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEP 629
Query: 684 IPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQ 743
Q QL Q ++ G G + S V + Q + G Q +
Sbjct: 630 EEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRV-SSQQTVSYGSQHEQAHSTG 688
Query: 744 QPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQP 803
+P +V Q P V PP+ + QG PS L S S + P Q
Sbjct: 689 TVPGHIPSTVQAQSQPHG--VYPPSS---VAQGQSQGQPS-SSSLTGVSSSQPIQHPQQQ 742
Query: 804 QGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPAT 863
QG++ A P + S S S +S+ ++ P P AP L Q P +
Sbjct: 743 QGIQQTAP-------PQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVS 795
Query: 864 QNGNLVQS------VSQPPLIATNTN---LPLAQQIP 891
Q +Q +QP ++ ++ LP+ Q +P
Sbjct: 796 QPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLP 832
>gi|19923597 Sin3A-associated protein, 130kDa isoform b [Homo
sapiens]
Length = 1048
Score = 71.2 bits (173), Expect = 5e-12
Identities = 183/899 (20%), Positives = 318/899 (35%), Gaps = 115/899 (12%)
Query: 38 ASALNAAGTGVGSNAT---SSEDFP---PPS--LLQPPPPAASSTSGPQPPPPQSLNLLS 89
A + A G G G SS+ FP PS L Q P A+S S P ++N S
Sbjct: 9 AGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDES 68
Query: 90 QAQLQA---QPLAPGGTQMKKKSGFQITSVTPAQISASISSNNSIAEDTESYDDLDESHT 146
+ + ++ + ++ + V P +S+++++A T +H
Sbjct: 69 GRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHL 128
Query: 147 ED---LSSSEILDVSLSRATDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPH 203
LS SE L + T P + TL+ + PG V+
Sbjct: 129 TPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLS--LPPKVPGQVTVTMES-------S 179
Query: 204 LPQQNVV----INGN-AHPHHLHHHHQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPV 258
+PQ + + I+G HP +LHH + + + + + ++ + G ++ V
Sbjct: 180 IPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAV 239
Query: 259 SRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNM-------RAPSTTGGIGINSVTGTS 311
SS T + PTS + ++ + + ++ R P TT +V T
Sbjct: 240 M------SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATV 293
Query: 312 TVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGT 371
+ + + + T S L +S + PSAA P + V I
Sbjct: 294 SATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPAL 353
Query: 372 ISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYE 431
+ + ++ TG V++ P + T+ S + T
Sbjct: 354 GTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTV 413
Query: 432 KENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEM-- 489
++ AT N V V I TS R + SS+ +S + S M
Sbjct: 414 PSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMET 473
Query: 490 ---GAPTVVVQQQQ---------QQQQQQQQQPALQGV-TLQQMDFGSTGPQSIPAVSIP 536
P+V VQ Q P V T++Q + P S
Sbjct: 474 RSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTG 533
Query: 537 QSISQS-QISQVQLQSQELSYQQK-QGLQPVPLQATMSAATGIQPSPVNVVGVTSA-LGQ 593
++ + ++ +QL + + S+ + QG+QP P+ + GIQP+P+ G+ A LG
Sbjct: 534 VGVASTVHLNPMQLMTVDASHARHIQGIQPAPI-----STQGIQPAPIGTPGIQPAPLGT 588
Query: 594 QPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPA 653
Q S A P+ T Q Q PM + Q P S
Sbjct: 589 QGIHS------------ATPINT-----------QGLQPAPMGTQQPQPEGKTSAVVLAD 625
Query: 654 SEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQ-----PTAVPAQPAGA 708
+ PI P SA A T V +Q P Q P+ + +PA
Sbjct: 626 GATIVANPI-------SNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATD 678
Query: 709 SVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVP----PSVIQQGAPPSS-- 762
+P + +++ T S Q + PT P+ Q P P++I +PPS
Sbjct: 679 GAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPA 738
Query: 763 ---QVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQP-----QGVEPVAQGIV 814
+P A I + T A + P + + S + PP P + VEP+
Sbjct: 739 VALSTIPGAVP--ITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRP 796
Query: 815 SQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVS 873
+P +++ + S+++ + S S +P + P+ +T+ G+++++ S
Sbjct: 797 VSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNS 855
Score = 35.8 bits (81), Expect = 0.22
Identities = 68/315 (21%), Positives = 109/315 (34%), Gaps = 48/315 (15%)
Query: 608 SQAAPPVQTPLPG-APPPQQL----QYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPI 662
SQ P + P G + P Q+ G P + G V+ A E++
Sbjct: 29 SQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVS---AREHMSSSSS 85
Query: 663 LQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSA 722
LQ+ +P V+ PQ L A P + P PA +
Sbjct: 86 LQSREEKQEP----------VVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLS 135
Query: 723 VPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAP 782
G P PS + P APPS+ +PP G + +++S P
Sbjct: 136 FSEGLM--------KPPPKPTMPSRPIAP------APPSTLSLPPKVPGQVTVTMESSIP 181
Query: 783 ---SLPQQLVIASQSS------LLTVPPQPQGVEPVAQG----IVSQQLPAVSSLPSA-S 828
++P + Q ++T Q + A G I + LP ++ + S
Sbjct: 182 QASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMS 241
Query: 829 SISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQ 888
S VT+ + T S +P+A T Q+I P + S + PP + + AQ
Sbjct: 242 SSKVTTVLRPT--SQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQ 299
Query: 889 QIPLSSTQFSAQSLA 903
+++T A A
Sbjct: 300 SPVITTTAAHATDSA 314
>gi|56549668 AT rich interactive domain 2 (ARID, RFX-like) [Homo
sapiens]
Length = 1835
Score = 71.2 bits (173), Expect = 5e-12
Identities = 162/695 (23%), Positives = 261/695 (37%), Gaps = 124/695 (17%)
Query: 368 GNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCT 427
G+ TI + + V N ++ +T +S Q V+T V ++ + P
Sbjct: 642 GSQTIGNHFQRTPVANQSSNLTATQMSFPVQG--VHTVAQTVSRIPQNPSPHT------- 692
Query: 428 EFYEKENA----VPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTES 483
++++NA + + + V TV QN I T G VS +V +
Sbjct: 693 --HQQQNAPVTVIQSKAPIPCEVVKATVIQNSIPQT-------GVPVSIAVGGGPPQSSV 743
Query: 484 VGSGEMGAPTVVVQQQQQQQQQQQ---QQPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS 540
V + G V V Q QQ L V Q+ G+ P ++ ++PQS
Sbjct: 744 VQNHSTGPQPVTVVNSQTLLHHPSVIPQQSPLHTVVPGQIPSGT--PVTVIQQAVPQSHM 801
Query: 541 QSQISQVQLQSQELSY-QQKQGLQPVPLQ-ATMSAATGIQPSPVNVVG----VTSALGQQ 594
++ + + +S QQ P P+Q ++ + G Q ++ VT++
Sbjct: 802 FGRVQNIPACTSTVSQGQQLITTSPQPVQTSSQQTSAGSQSQDTVIIAPPQYVTTSASNI 861
Query: 595 PSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQ----QPMVSTQMAPGHVKSVTQ 650
S +S+ Q+ Q + G P PQ + G Q +P+ S Q++ V+ Q
Sbjct: 862 VSATSVQNFQVATGQ-----MVTIAGVPSPQASRVGFQNIAPKPLPSQQVSSTVVQQPIQ 916
Query: 651 NPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASV 710
P QQP Q+ + QP+ G T P + P A PAG +V
Sbjct: 917 QP------QQPTQQSVVIVSQPAQQG----QTYAPAIHQIVLANPA------ALPAGQTV 960
Query: 711 QPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPS-SQVVPPAQ 769
Q GQ S+ P+ N +PTA+ ST P S QG PP+ SQ++ +
Sbjct: 961 QLTGQPNITPSSSPSPVPATN----NQVPTAMSSSST--PQS---QGPPPTVSQMLSVKR 1011
Query: 770 TGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASS 829
Q Q S PQQ+ + Q QPQ V+ Q QQ A P++
Sbjct: 1012 ----QQQQQHSPAPPPQQVQVQVQ--------QPQQVQMQVQ---PQQSNAGVGQPASGE 1056
Query: 830 ISVTSQV-----SSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQS--------VSQPP 876
S+ Q+ + P G P +PP N A+ P+ Q V S Q P
Sbjct: 1057 SSLIKQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQVASNQAAGFGVQGQTP 1116
Query: 877 ---LIATNTNLPL----------AQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVG 923
L+ N+ L Q +P+S+ Q L + I + ++
Sbjct: 1117 AQQLLVGQQNVQLVPSAMPPSGGVQTVPISNLQILPGPLISNSPATIFQGTSGNQVTITV 1176
Query: 924 LPQTISGDSGGMSAVSDGSSSSLAASASL----------FPLKVLPLTTPLVDGEDESSS 973
+P T S + VS G+++ L A A + P++ LP T G+ ++
Sbjct: 1177 VPNT----SFAPATVSQGNATQLIAPAGITMSGTQTGVGLPVQTLPATQASPAGQSSCTT 1232
Query: 974 GASVVAIDNKIEQAMDLVKSHLMYAVRE-EVEVLK 1007
D I Q + K V E ++EV++
Sbjct: 1233 ATPPFKGDKIICQKEEEAKEATGLHVHERKIEVME 1267
Score = 65.5 bits (158), Expect = 3e-10
Identities = 122/478 (25%), Positives = 181/478 (37%), Gaps = 93/478 (19%)
Query: 652 PASEYVQQQPILQTAMS-------SGQPSSAGVGAGTTVI-------PVAQPQG------ 691
P Y QQQP+ + + S PS AG+ G+ I PVA
Sbjct: 607 PIQMYYQQQPVSTSVVRVDSVPDVSPAPSPAGIPHGSQTIGNHFQRTPVANQSSNLTATQ 666
Query: 692 IQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIP------TAVQQ- 744
+ PVQ AQ +V + Q P+ + + + I +A IP T +Q
Sbjct: 667 MSFPVQGVHTVAQ----TVSRIPQNPSPHTHQQQNAPVTVIQSKAPIPCEVVKATVIQNS 722
Query: 745 -PSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQ- 802
P T VP S+ G PP S VV TG V S L VI QS L TV P
Sbjct: 723 IPQTGVPVSIAVGGGPPQSSVVQNHSTGPQPVTVVNSQTLLHHPSVIPQQSPLHTVVPGQ 782
Query: 803 -PQGVEPVAQGIVSQQLP------AVSSLPS-ASSISVTSQVSSTGP-----------SG 843
P G PV ++ Q +P V ++P+ S++S Q+ +T P +G
Sbjct: 783 IPSGT-PVT--VIQQAVPQSHMFGRVQNIPACTSTVSQGQQLITTSPQPVQTSSQQTSAG 839
Query: 844 MPSAPTNLV-PPQ-------NIAQTPATQN-----GNLVQSVSQPPLIATNTNLPLAQQI 890
S T ++ PPQ NI + QN G +V P A+
Sbjct: 840 SQSQDTVIIAPPQYVTTSASNIVSATSVQNFQVATGQMVTIAGVPSPQASRVGFQNIAPK 899
Query: 891 PLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAA-- 948
PL S Q S+ + Q I+ ++ + S+V + Q A+ ++ AA
Sbjct: 900 PLPSQQVSSTVVQQ----PIQQPQQPTQQSVVIVSQPAQQGQTYAPAIHQIVLANPAALP 955
Query: 949 SASLFPLKVLPLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKE 1008
+ L P TP SSS + V A +N++ AM + + +
Sbjct: 956 AGQTVQLTGQPNITP-------SSSPSPVPATNNQVPTAMSSSST-------PQSQGPPP 1001
Query: 1009 QIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPAS 1066
+ +++ Q +Q++ + A P Q Q Q Q Q QPQ + QPAS
Sbjct: 1002 TVSQMLSVKRQQQQQH----SPAPPPQQVQVQVQ-QPQQVQMQVQPQQSNAGVGQPAS 1054
Score = 61.6 bits (148), Expect = 4e-09
Identities = 107/410 (26%), Positives = 153/410 (37%), Gaps = 54/410 (13%)
Query: 564 PVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPP 623
P+P+Q QP +VV V S P+ S P + +TP+ A
Sbjct: 605 PLPIQMYYQQ----QPVSTSVVRVDSVPDVSPAPSPAGIPHGSQTIGNHFQRTPV--ANQ 658
Query: 624 PQQLQYGQQQ-PMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTT 682
L Q P+ V + QNP+ QQQ T + S P V T
Sbjct: 659 SSNLTATQMSFPVQGVHTVAQTVSRIPQNPSPHTHQQQNAPVTVIQSKAPIPCEV-VKAT 717
Query: 683 VIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIAN---IGQQANIP 739
VI + PQ +PV P + VQ P V+ V + + + + I QQ+ +
Sbjct: 718 VIQNSIPQ-TGVPVSIAVGGGPPQSSVVQNHSTGPQPVTVVNSQTLLHHPSVIPQQSPLH 776
Query: 740 TAVQ-QPSTQVPPSVIQQGAPPSSQVVP----PAQTGIIHQGVQ--TSAP----SLPQQL 788
T V Q + P +VIQQ P S PA T + QG Q T++P + QQ
Sbjct: 777 TVVPGQIPSGTPVTVIQQAVPQSHMFGRVQNIPACTSTVSQGQQLITTSPQPVQTSSQQT 836
Query: 789 VIASQSSLLTVPPQPQGVEPVAQGIVSQ-----------QLPAVSSLPSASSISVTSQVS 837
SQS + PQ V A IVS Q+ ++ +PS + V Q
Sbjct: 837 SAGSQSQDTVIIAPPQYVTTSASNIVSATSVQNFQVATGQMVTIAGVPSPQASRVGFQ-- 894
Query: 838 STGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPP-------------LIATNTNL 884
+ P +PS + Q Q P V VSQP ++A L
Sbjct: 895 NIAPKPLPSQQVSSTVVQQPIQQPQQPTQQSVVIVSQPAQQGQTYAPAIHQIVLANPAAL 954
Query: 885 PLAQQIPLSS----TQFSAQSLAQAIGSQIEDARRAAE-PSLVGLPQTIS 929
P Q + L+ T S+ S A +Q+ A ++ P G P T+S
Sbjct: 955 PAGQTVQLTGQPNITPSSSPSPVPATNNQVPTAMSSSSTPQSQGPPPTVS 1004
Score = 55.5 bits (132), Expect = 3e-07
Identities = 131/522 (25%), Positives = 187/522 (35%), Gaps = 82/522 (15%)
Query: 246 SASITGGPPSSPVSRKLSTTGSS------------DSITPV-APTSAVSS----SGSPAS 288
S ++ GGPP S V + ST S+ P +P V SG+P +
Sbjct: 731 SIAVGGGPPQSSVVQNHSTGPQPVTVVNSQTLLHHPSVIPQQSPLHTVVPGQIPSGTPVT 790
Query: 289 VMTNMRAPSTTGGIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGN------------- 335
V+ S G N TSTV+ S P TSS +
Sbjct: 791 VIQQAVPQSHMFGRVQNIPACTSTVSQGQQLITTSPQPVQTSSQQTSAGSQSQDTVIIAP 850
Query: 336 ---VNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGS 392
V S SNI SA V V +G V I +G+ + S + P S
Sbjct: 851 PQYVTTSASNIVSATSVQ-NFQVATGQMVTI-AGVPSPQASRVGFQNIAPKPLPSQQVSS 908
Query: 393 VSSQQ--QQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVET 450
QQ QQP T + V+ S+P ++G + PA +++
Sbjct: 909 TVVQQPIQQPQQPTQQSVVIV----SQPAQQG----------QTYAPAIHQIVLANPAAL 954
Query: 451 VKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGE----MGAPTVVVQQ---QQQQQ 503
+++T + T SS S +T + ++ S G P V Q ++QQQ
Sbjct: 955 PAGQTVQLTGQPNITPSSSPSPVPATNNQVPTAMSSSSTPQSQGPPPTVSQMLSVKRQQQ 1014
Query: 504 QQQQQQPALQGVTLQ-----QMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQ 558
QQ P Q V +Q Q+ QS V P S S I Q+ L + S
Sbjct: 1015 QQHSPAPPPQQVQVQVQQPQQVQMQVQPQQSNAGVGQPASGESSLIKQLLLPKRGPSTPG 1074
Query: 559 KQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPL 618
+ + P P + A P V V A G + AQ L Q V
Sbjct: 1075 GKLILPAPQIPPPNNARAPSPQVVYQVASNQAAGFGVQGQTPAQQLLVGQQNVQLV---- 1130
Query: 619 PGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYV----QQQPILQTAMSSGQPSS 674
P A PP Q P+ + Q+ PG + ++ +PA+ + Q I +S P++
Sbjct: 1131 PSAMPPS--GGVQTVPISNLQILPGPL--ISNSPATIFQGTSGNQVTITVVPNTSFAPAT 1186
Query: 675 AGVGAGTTVIPVA------QPQGIQLPVQP-TAVPAQPAGAS 709
G T +I A G+ LPVQ A A PAG S
Sbjct: 1187 VSQGNATQLIAPAGITMSGTQTGVGLPVQTLPATQASPAGQS 1228
Score = 49.3 bits (116), Expect = 2e-05
Identities = 167/780 (21%), Positives = 279/780 (35%), Gaps = 148/780 (18%)
Query: 22 MAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPPPSLLQPPPPAASSTSGP--QP 79
+A+PA P +G L TG + SS P P+ P A SS+S P Q
Sbjct: 948 LANPAALP-----AGQTVQL----TGQPNITPSSSPSPVPATNNQVPTAMSSSSTPQSQG 998
Query: 80 PPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQISASISSNNSIAEDTESYD 139
PPP +LS + Q Q +P + Q+ P Q+ + S A
Sbjct: 999 PPPTVSQMLSVKRQQQQQHSPAPPPQQ----VQVQVQQPQQVQMQVQPQQSNA------- 1047
Query: 140 DLDESHTEDLSSSEILDVSLSRATDLGEP---ERSSSEETLNNFQEAETPGA--VSPNQP 194
+G+P E S ++ L + TPG + P P
Sbjct: 1048 ------------------------GVGQPASGESSLIKQLLLPKRGPSTPGGKLILP-AP 1082
Query: 195 HLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPSHVAVASASITGGPP 254
+P P+ P VV + + + G G + V ++ P
Sbjct: 1083 QIPPPNNARAPSPQVV-------YQVASNQAAGFG---VQGQTPAQQLLVGQQNVQLVPS 1132
Query: 255 SSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTGGIGINSVTGTSTVN 314
+ P S + T S+ + P +S+ SPA++ GTS N
Sbjct: 1133 AMPPSGGVQTVPISN--LQILPGPLISN--SPATIF-----------------QGTSG-N 1170
Query: 315 NVNITAV--GSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTI 372
V IT V SF P S GN + + + AG+++ G +GV + + + T
Sbjct: 1171 QVTITVVPNTSFAPATVSQ--GN----ATQLIAPAGITMS-GTQTGVGLPVQT--LPATQ 1221
Query: 373 SSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRV--VKLDSSSEP-FKKGRWTCTEF 429
+S A SS A G + Q+++ + V K++ P ++G +
Sbjct: 1222 ASPAGQSSCTTATPPFKGDKIICQKEEEAKEATGLHVHERKIEVMENPSCRRGATNTSNG 1281
Query: 430 YEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEM 489
KEN + G L+N + P + + +S + S E+ SG+
Sbjct: 1282 DTKENEMHV--GSLLNGRKYSDSSLPPSNSGKIQSETNQCSLISNGPSLELGENGASGKQ 1339
Query: 490 GAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQL 549
+ Q Q + ++P + G+ GS ++IP + +IS ++
Sbjct: 1340 NSE----QIDMQDIKSDLRKPLVNGICDFDKGDGSHLSKNIPNHKTSNHVGNGEISPMEP 1395
Query: 550 QSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQ 609
Q L Q+ + L+ I PV +G +S Q + ++ Q
Sbjct: 1396 QG-TLDITQQDTAKGDQLER-------ISNGPVLTLGGSSVSSIQEASNAATQQFSGTDL 1447
Query: 610 AAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHV--------KSVTQNPA-------- 653
P+ + L + PQQ P +T + GH V+ +PA
Sbjct: 1448 LNGPLASSL-NSDVPQQRPSVVVSPHSTTSVIQGHQIIAVPDSGSKVSHSPALSSDVRST 1506
Query: 654 SEYVQQQPILQTAMSSGQPSSAGV--GAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQ 711
+ + + + + A + + + AG+ G ++ ++ P AVPA
Sbjct: 1507 NGTAECKTVKRPAEDTDRETVAGIPNKVGVRIVTISDPNNAGCSATMVAVPA-------- 1558
Query: 712 PVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQ---PSTQVPPS--VIQQGAPPSSQVVP 766
G P+ V+ V S + +Q + PT VQ +T +PPS V QG P SSQ P
Sbjct: 1559 --GADPSTVAKVAIESAVQQ--KQQHPPTYVQNVVPQNTPMPPSPAVQVQGQPNSSQPSP 1614
Score = 36.2 bits (82), Expect = 0.17
Identities = 42/153 (27%), Positives = 65/153 (42%), Gaps = 14/153 (9%)
Query: 466 SGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGST 525
SGS VS S + S + G+ E TV + ++ P GV + + +
Sbjct: 1489 SGSKVSHSPALSSDVRSTNGTAE--CKTVKRPAEDTDRETVAGIPNKVGVRIVTISDPNN 1546
Query: 526 GPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSP-VNV 584
S V++P S +++V ++S + QQKQ P +Q + T + PSP V V
Sbjct: 1547 AGCSATMVAVPAGADPSTVAKVAIES---AVQQKQQHPPTYVQNVVPQNTPMPPSPAVQV 1603
Query: 585 VGVTSALGQQPSISSLAQPQLPYSQAAPPVQTP 617
G QP+ SS P SQ P++ P
Sbjct: 1604 QG-------QPN-SSQPSPFSGSSQPGDPMRKP 1628
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 70.9 bits (172), Expect = 6e-12
Identities = 142/682 (20%), Positives = 224/682 (32%), Gaps = 110/682 (16%)
Query: 214 NAHPHHLHHHHQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITP 273
N+H H +H ++ ++ + P A A +S GG P S G++ +
Sbjct: 201 NSHDHGFPNHQ--YNSYYPNRSAYPPPAPAYALSSPRGGTPGS---------GAAAAAGS 249
Query: 274 VAPTSAVSSSGSPASVMTNMR-------APSTTGGIGINSVTGTSTVNNVNITAVGSFNP 326
P S+ +S+ S +S R PS GG G T T T+N + + P
Sbjct: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG-GTPQPTATPTLNQLLTS------P 302
Query: 327 NVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNA-- 384
+ G S P G GP + + +S A +A
Sbjct: 303 SSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPM 362
Query: 385 AAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATE---- 440
+ G +GG + P ++ ++ K+ +P+ T Y ++ P+
Sbjct: 363 SPGSSGGGGQPLARTPQPSSPMDQMGKM--RPQPYGG-----TNPYSQQQGPPSGPQQGH 415
Query: 441 ---GVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQ 497
G +T ++ P+ + +S G YT+ + P+ Q
Sbjct: 416 GYPGQPYGS--QTPQRYPMTMQGRAQSAMGGL---------SYTQQIPPYGQQGPSGYGQ 464
Query: 498 QQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQ 557
Q Q QQ Q QQ + P P P Q Q QLQS + Y
Sbjct: 465 QGQTPYYNQQSPHPQQ----QQPPYSQQPPSQTPHAQ-PSYQQQPQSQPPQLQSSQPPYS 519
Query: 558 QKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQ--AAPPVQ 615
Q+ P Q SP S Q P Q Q PYSQ A P Q
Sbjct: 520 QQPSQPPH------------QQSPAPYPSQQSTTQQHP------QSQPPYSQPQAQSPYQ 561
Query: 616 TPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSA 675
P P P L P +Q + S + P + + Q A S+ +S+
Sbjct: 562 QQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSS 621
Query: 676 GVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQ 735
G + + L +P+++P P+G A V T ++ G+Q
Sbjct: 622 KGGQ--------EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQ 673
Query: 736 ANIPTAVQQPSTQV---------------PPSVIQQ-------GAPPSSQVVPPAQTGII 773
+N + P T P SV Q A P +Q+ P +G
Sbjct: 674 SNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSG-- 731
Query: 774 HQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVT 833
Q PS+ Q + + + P PQ P +S + P+ + +
Sbjct: 732 -QSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQ 790
Query: 834 SQVSSTGPSGMPSAPTNLVPPQ 855
+ + S GP G P P Q
Sbjct: 791 NSMGSYGPQGGQYGPQGGYPRQ 812
Score = 58.2 bits (139), Expect = 4e-08
Identities = 104/433 (24%), Positives = 154/433 (35%), Gaps = 53/433 (12%)
Query: 503 QQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQK--- 559
QQQ QG +GS PQ P Q +QS + + Q Y Q+
Sbjct: 403 QQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTM--QGRAQSAMGGLSYTQQIPPYGQQGPS 460
Query: 560 ----QGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQ 615
QG P Q S Q P + + QPS Q Q P Q++ P
Sbjct: 461 GYGQQGQTPYYNQ--QSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPY 518
Query: 616 TPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSA 675
+ P PP QQ S P + Q+P S+ QP Q+ QP
Sbjct: 519 SQQPSQPPHQQ----------SPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQP 568
Query: 676 GVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQ 735
+ QPQ Q Q TA +Q Q + Q A S ++ G Q
Sbjct: 569 APSTLSQQAAYPQPQSQQ--SQQTAY-SQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ 625
Query: 736 ANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSS 795
++ ++Q + +P S +P G + GV TS S Q QS+
Sbjct: 626 EDMNLSLQSRPSSLP------DLSGSIDDLPMGTEGALSPGVSTSGISSSQ----GEQSN 675
Query: 796 LLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQV--SSTGPSGMPSAPTNLVP 853
P P S LP + PS S + + V S +GP + P N +P
Sbjct: 676 PAQSPFSPH---------TSPHLPGIRG-PSPSPVGSPASVAQSRSGPLSPAAVPGNQMP 725
Query: 854 PQNIAQTPATQNGNLVQ-SVSQPPLIATNTNLPLAQQIPLSST--QFSAQSLAQAIGSQI 910
P + P+ Q+ +++ S++Q + + Q+P S+ SA S Q G QI
Sbjct: 726 P----RPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQI 781
Query: 911 EDARRAAEPSLVG 923
+ + + +G
Sbjct: 782 HTGMGSYQQNSMG 794
Score = 37.7 bits (86), Expect = 0.059
Identities = 81/325 (24%), Positives = 108/325 (33%), Gaps = 72/325 (22%)
Query: 489 MGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQ 548
M +P+ QQQQQQQQ+ Q T Q GS P
Sbjct: 1318 MYSPSRYPPQQQQQQQQRHDSYGNQFST-QGTPSGSPFP--------------------- 1355
Query: 549 LQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYS 608
Q YQQ+Q P+ T + V ++ GQ Q QLP +
Sbjct: 1356 -SQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQP------QQQQLPPA 1408
Query: 609 QAAPPVQTPLPGAPPPQQL--QYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTA 666
Q P Q P Q + QYG P +T + + PA Q P
Sbjct: 1409 QPQPASQQQAAQPSPQQDVYNQYGNAYPATAT-------AATERRPAGGPQNQFPFQFGR 1461
Query: 667 MSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAG------------ASVQPVG 714
P GT PQ + P+Q +A AQ A+ Q G
Sbjct: 1462 DRVSAP------PGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTG 1515
Query: 715 QAP--AAVSAVPTGSQIANIGQQANIPTAVQQ---------PSTQVPPSVIQQGAPPSSQ 763
AP A V ++ + Q+AN + PS VPP PPS+
Sbjct: 1516 SAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPP---MTRPPPSNY 1572
Query: 764 VVPPAQTGIIHQGVQTSAPSLPQQL 788
PP+ I Q V + AP LP+ +
Sbjct: 1573 QPPPSMQNHIPQ-VSSPAP-LPRPM 1595
Score = 30.4 bits (67), Expect = 9.4
Identities = 14/28 (50%), Positives = 14/28 (50%)
Query: 65 QPPPPAASSTSGPQPPPPQSLNLLSQAQ 92
Q P AASS P PPPP L Q Q
Sbjct: 4 QVAPAAASSLGNPPPPPPSELKKAEQQQ 31
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 70.9 bits (172), Expect = 6e-12
Identities = 142/682 (20%), Positives = 224/682 (32%), Gaps = 110/682 (16%)
Query: 214 NAHPHHLHHHHQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITP 273
N+H H +H ++ ++ + P A A +S GG P S G++ +
Sbjct: 201 NSHDHGFPNHQ--YNSYYPNRSAYPPPAPAYALSSPRGGTPGS---------GAAAAAGS 249
Query: 274 VAPTSAVSSSGSPASVMTNMR-------APSTTGGIGINSVTGTSTVNNVNITAVGSFNP 326
P S+ +S+ S +S R PS GG G T T T+N + + P
Sbjct: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG-GTPQPTATPTLNQLLTS------P 302
Query: 327 NVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNA-- 384
+ G S P G GP + + +S A +A
Sbjct: 303 SSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPM 362
Query: 385 AAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATE---- 440
+ G +GG + P ++ ++ K+ +P+ T Y ++ P+
Sbjct: 363 SPGSSGGGGQPLARTPQPSSPMDQMGKM--RPQPYGG-----TNPYSQQQGPPSGPQQGH 415
Query: 441 ---GVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQ 497
G +T ++ P+ + +S G YT+ + P+ Q
Sbjct: 416 GYPGQPYGS--QTPQRYPMTMQGRAQSAMGGL---------SYTQQIPPYGQQGPSGYGQ 464
Query: 498 QQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQ 557
Q Q QQ Q QQ + P P P Q Q QLQS + Y
Sbjct: 465 QGQTPYYNQQSPHPQQ----QQPPYSQQPPSQTPHAQ-PSYQQQPQSQPPQLQSSQPPYS 519
Query: 558 QKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQ--AAPPVQ 615
Q+ P Q SP S Q P Q Q PYSQ A P Q
Sbjct: 520 QQPSQPPH------------QQSPAPYPSQQSTTQQHP------QSQPPYSQPQAQSPYQ 561
Query: 616 TPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSA 675
P P P L P +Q + S + P + + Q A S+ +S+
Sbjct: 562 QQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSS 621
Query: 676 GVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQ 735
G + + L +P+++P P+G A V T ++ G+Q
Sbjct: 622 KGGQ--------EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQ 673
Query: 736 ANIPTAVQQPSTQV---------------PPSVIQQ-------GAPPSSQVVPPAQTGII 773
+N + P T P SV Q A P +Q+ P +G
Sbjct: 674 SNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSG-- 731
Query: 774 HQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVT 833
Q PS+ Q + + + P PQ P +S + P+ + +
Sbjct: 732 -QSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQ 790
Query: 834 SQVSSTGPSGMPSAPTNLVPPQ 855
+ + S GP G P P Q
Sbjct: 791 NSMGSYGPQGGQYGPQGGYPRQ 812
Score = 58.2 bits (139), Expect = 4e-08
Identities = 104/433 (24%), Positives = 154/433 (35%), Gaps = 53/433 (12%)
Query: 503 QQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQK--- 559
QQQ QG +GS PQ P Q +QS + + Q Y Q+
Sbjct: 403 QQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTM--QGRAQSAMGGLSYTQQIPPYGQQGPS 460
Query: 560 ----QGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQ 615
QG P Q S Q P + + QPS Q Q P Q++ P
Sbjct: 461 GYGQQGQTPYYNQ--QSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPY 518
Query: 616 TPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSA 675
+ P PP QQ S P + Q+P S+ QP Q+ QP
Sbjct: 519 SQQPSQPPHQQ----------SPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQP 568
Query: 676 GVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQ 735
+ QPQ Q Q TA +Q Q + Q A S ++ G Q
Sbjct: 569 APSTLSQQAAYPQPQSQQ--SQQTAY-SQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ 625
Query: 736 ANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSS 795
++ ++Q + +P S +P G + GV TS S Q QS+
Sbjct: 626 EDMNLSLQSRPSSLP------DLSGSIDDLPMGTEGALSPGVSTSGISSSQ----GEQSN 675
Query: 796 LLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQV--SSTGPSGMPSAPTNLVP 853
P P S LP + PS S + + V S +GP + P N +P
Sbjct: 676 PAQSPFSPH---------TSPHLPGIRG-PSPSPVGSPASVAQSRSGPLSPAAVPGNQMP 725
Query: 854 PQNIAQTPATQNGNLVQ-SVSQPPLIATNTNLPLAQQIPLSST--QFSAQSLAQAIGSQI 910
P + P+ Q+ +++ S++Q + + Q+P S+ SA S Q G QI
Sbjct: 726 P----RPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQI 781
Query: 911 EDARRAAEPSLVG 923
+ + + +G
Sbjct: 782 HTGMGSYQQNSMG 794
Score = 31.2 bits (69), Expect = 5.5
Identities = 39/131 (29%), Positives = 48/131 (36%), Gaps = 32/131 (24%)
Query: 489 MGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQ 548
M +P+ QQQQQQQQ+ Q T Q GS P
Sbjct: 1318 MYSPSRYPPQQQQQQQQRHDSYGNQFST-QGTPSGSPFPS-------------------- 1356
Query: 549 LQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYS 608
Q + QQ+Q P PL M T SP + S + Q A P +P S
Sbjct: 1357 -QQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPF----LHSGMKMQK-----AGPPVPAS 1406
Query: 609 QAAP-PVQTPL 618
AP PVQ P+
Sbjct: 1407 HIAPAPVQPPM 1417
Score = 30.4 bits (67), Expect = 9.4
Identities = 14/28 (50%), Positives = 14/28 (50%)
Query: 65 QPPPPAASSTSGPQPPPPQSLNLLSQAQ 92
Q P AASS P PPPP L Q Q
Sbjct: 4 QVAPAAASSLGNPPPPPPSELKKAEQQQ 31
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 70.9 bits (172), Expect = 6e-12
Identities = 124/532 (23%), Positives = 194/532 (36%), Gaps = 67/532 (12%)
Query: 454 NPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQ 513
+P + + G + S+ +L Y + + + +V QQ PA+
Sbjct: 646 SPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMS 705
Query: 514 GVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSA 573
+ + ST + P P ++Q Q L+ Q LQPVP
Sbjct: 706 FAPV--LPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVP------- 756
Query: 574 ATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAA--PPVQTPLPGAPPPQQLQYGQ 631
P + S +G + L PQ P A PP P+P PP L
Sbjct: 757 -----PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGID 811
Query: 632 QQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQG 691
P + V V P +Y IL + + P+S + +P
Sbjct: 812 GLPPALPDLPTATVPPV---PPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAP 868
Query: 692 IQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPS-TQVP 750
+ +P + T VP PA ++ + AP V+A+ S +A + Q P A Q + T VP
Sbjct: 869 LAMPCR-TIVPNAPA--TIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVP 925
Query: 751 PSVI-----------QQGAPPSSQVVP----------PAQTGIIHQGVQTSAPSLPQQLV 789
PS Q PP + P P Q + Q + P LP Q +
Sbjct: 926 PSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPM 985
Query: 790 IASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVS-------SLPSASSISVTSQVSS--TG 840
+ Q L P P EP+ + Q PA + P+ ++ V +QV +
Sbjct: 986 LPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP 1045
Query: 841 PSGM--PSAPTNLVP--PQNIAQTP---ATQNGNLVQSVSQPPLIATNTNLPLAQQIPLS 893
P+ + P P L+P P+ + Q P AT + ++ +Q + N PL ++
Sbjct: 1046 PAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIA 1105
Query: 894 STQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSS 945
S + Q + + Q E A + P GLPQ S +S G S V+ G S
Sbjct: 1106 SPCPTVQLTVEPV--QEEQASQDKPP---GLPQ--SCESYGGSDVTSGKELS 1150
Score = 50.1 bits (118), Expect = 1e-05
Identities = 142/640 (22%), Positives = 216/640 (33%), Gaps = 122/640 (19%)
Query: 186 PGAVSPNQPHLP---QPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPSHV 242
P V P QP LP +P PHLP+Q A P G + GH P V
Sbjct: 988 PQPVLPPQPALPVRPEPLQPHLPEQAAPA---ATP-----------GSQILLGHPAPYAV 1033
Query: 243 AVASASIT-GGPPSSPVSRKLSTT--GSSDSITPVAPTSAVSSSGSPASVMTNMRA---- 295
VA+ T PP++ +S L ++ + P P+S + S S SV T
Sbjct: 1034 DVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPP 1093
Query: 296 --PSTTGGIGINSVTGT--STVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSV 351
P GG GI S T TV V P +P +
Sbjct: 1094 ANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKP--------------PGLPQSCESYG 1139
Query: 352 GPGVTSG--VNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRV 409
G VTSG ++ + G G + AA + + +S+ + +N
Sbjct: 1140 GSDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGD 1199
Query: 410 VKLDSSSEPFKKGRWT-------------CTEFYEKENAVPATEGVLINKVVETVKQNPI 456
++ E T T E + + A I ++ + + +
Sbjct: 1200 KMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAED 1259
Query: 457 EVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVT 516
++ + ++ GS +S LS T +G+GE + +Q Q P Q
Sbjct: 1260 MLSEDTDADRGSDPGTSPPHLS--TCGLGTGE------------ESRQSQANAPVYQQNV 1305
Query: 517 LQ--QMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAA 574
L + F PA P+S +S + ++ + S K L +
Sbjct: 1306 LHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQL-----------S 1354
Query: 575 TGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQT-PLPGAPPPQQLQYGQQQ 633
+ QPS + L Q + P P + ++PPV P GA P
Sbjct: 1355 SKEQPS---FLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPAS 1411
Query: 634 PMVSTQMAPGHVKSVTQNPASEYVQQQPILQT--AMSSGQPSSAGVGAGTTVIPVAQPQG 691
S PG + +T SE QP+ +T A + QP G+ T A +
Sbjct: 1412 GTASQAGGPGTPQGLT----SELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRD 1467
Query: 692 IQLPVQPTAVPA--------QPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQ 743
P +P PA P A QP PAAV AV + Q
Sbjct: 1468 ASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATS--------------Q 1513
Query: 744 QPSTQVPPSVIQQGAPPSSQVV----PPAQTGIIHQGVQT 779
PS + P+V Q PPS+ PP + G + +++
Sbjct: 1514 LPSPPLGPTVPPQ--PPSALESDGEGPPPRVGFVDSTIKS 1551
Score = 43.9 bits (102), Expect = 8e-04
Identities = 70/284 (24%), Positives = 106/284 (37%), Gaps = 57/284 (20%)
Query: 614 VQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSS-GQP 672
V +P PP LQ + Q P + P ++ P L T+ +S
Sbjct: 558 VGSPDKARGPPVPLQVQVTYHAQAGQPGPPE----PEEPEADQHLLPPTLPTSATSLASD 613
Query: 673 SSAGVGAGTTVIPVAQP--QGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPT----- 725
S+ G G+TV +Q Q + L A P+ PV + P ++P+
Sbjct: 614 STFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQ 673
Query: 726 ------GSQIANIGQQANIPTAVQQ---------------PSTQVPPSVIQQGAPPSSQV 764
G + ++ A P ++QQ PST +P Q APP Q
Sbjct: 674 QPTAAPGLPVGSVPAPA-CPPSLQQHFPDPAMSFAPVLPPPSTPMPTGP-GQPAPPGQQP 731
Query: 765 VPPAQTGIIHQ--------GVQTSAPSLPQQLVIASQSSL------LTVPPQPQGVEPVA 810
P AQ + Q +Q P LP L ASQ L +P P ++P+A
Sbjct: 732 PPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAP--LQPLA 789
Query: 811 QGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPP 854
Q V Q+P + +P + ++ + P +P PT VPP
Sbjct: 790 Q--VPPQMPPIPVVPPITPLAGIDGL----PPALPDLPTATVPP 827
Score = 35.8 bits (81), Expect = 0.22
Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 6/83 (7%)
Query: 5 PESTAAAAAAADISARKMAHPAMFPRRGSGS-----GSASALNAAGTGVGSNATSSEDFP 59
P AA+ A + PA P SG+ G + L A G S ATS P
Sbjct: 1458 PAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSP 1517
Query: 60 PPSLLQPP-PPAASSTSGPQPPP 81
P PP PP+A + G PPP
Sbjct: 1518 PLGPTVPPQPPSALESDGEGPPP 1540
Score = 33.1 bits (74), Expect = 1.4
Identities = 46/206 (22%), Positives = 76/206 (36%), Gaps = 44/206 (21%)
Query: 695 PVQPTAVPAQPAGASVQPVGQAP--AAVSAVPTGSQIANIGQQANI-------------- 738
PV P P + P+ P A+ + P Q+++ Q + +
Sbjct: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNP 1376
Query: 739 ---PTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSS 795
P A PS+ ++ Q GA P++ +P +G Q P PQ L ++S
Sbjct: 1377 PGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASG---TASQAGGPGTPQGLTSELETS 1433
Query: 796 --LLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVP 853
L P V+P+ G+ P + +AS+ SAP +P
Sbjct: 1434 QPLAETHEAPLAVQPLVVGLA----PCTPAPEAASTRDA-------------SAPREPLP 1476
Query: 854 PQNIAQTPATQNGNLVQSVSQP-PLI 878
P A P+ +G ++ QP PL+
Sbjct: 1477 PP--APEPSPHSGTPQPALGQPAPLL 1500
Score = 31.2 bits (69), Expect = 5.5
Identities = 40/164 (24%), Positives = 64/164 (39%), Gaps = 14/164 (8%)
Query: 766 PPAQTGIIHQGVQ--TSAPSLPQQLVIASQSSLLTVPPQP-QGVEPVAQGIVSQQLPAVS 822
P Q ++H G + P A +SS PP P + P A + +S
Sbjct: 1299 PVYQQNVLHTGKRWFIICPVAEHPAPEAPESS----PPLPLSSLPPEASQDSAPYKDQLS 1354
Query: 823 SLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNT 882
S S ++ +S GPS P AP + P + T Q+G + + P +
Sbjct: 1355 SKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTA 1414
Query: 883 NLPLAQQIP--LSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGL 924
+ P L+S ++Q LA+ +A A +P +VGL
Sbjct: 1415 SQAGGPGTPQGLTSELETSQPLAET-----HEAPLAVQPLVVGL 1453
Score = 30.8 bits (68), Expect = 7.2
Identities = 17/42 (40%), Positives = 19/42 (45%), Gaps = 1/42 (2%)
Query: 59 PPPSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAP 100
PPPS P P + G QPPP L Q L QP+ P
Sbjct: 711 PPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQV-LAPQPVVP 751
>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 69.7 bits (169), Expect = 1e-11
Identities = 123/477 (25%), Positives = 187/477 (39%), Gaps = 83/477 (17%)
Query: 382 PNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEG 441
PN + SS+Q QP + S+ + L SS P ++ + ++
Sbjct: 1020 PNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQD----------QQSTNIFLSQS 1069
Query: 442 VLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQ 501
+ N TV Q E + +S+S ST + +E + + AP + Q
Sbjct: 1070 PMNNLQTNTVAQ-------EAFFAAPNSISPLQSTSN--SEQQAAFQQQAP--ISHIQTP 1118
Query: 502 QQQQQQQQPALQGVTLQQMDFGSTGPQSIP------------AVSIPQSISQSQISQVQL 549
Q+Q QP QG+ Q+ GS P +P ++ QS S SQ Q Q
Sbjct: 1119 MLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQ 1178
Query: 550 QSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQ 609
Q Q+ QQ+Q Q TM+ + P N++ + Q P + Q Q + Q
Sbjct: 1179 QQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPN---QNPMANQEQQNQSIFHQ 1235
Query: 610 AAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSS 669
Q+ + QQ Q Q VS+ PG TQ+ +S+ Q +
Sbjct: 1236 -----QSNMAPMNQEQQPMQFQSQSTVSSLQNPG----PTQSESSQTPLFHSSPQIQLVQ 1286
Query: 670 GQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAP--AAVSAVPTGS 727
G PSS Q Q + L + P ++ A + Q + Q+P + + +P G
Sbjct: 1287 GSPSS-------------QEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMP-GI 1332
Query: 728 QIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQ-------TS 780
Q A Q P A +T Q +P SSQ +G+ G+Q TS
Sbjct: 1333 QGATSSPQ---PQATLFHNTAGGTMNQLQNSPGSSQ----QTSGMFLFGIQNNCSQLLTS 1385
Query: 781 AP-SLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQV 836
P +LP QL+ SQ PQ +G PV ++SQQ+P S P ASSI+ +
Sbjct: 1386 GPATLPDQLMAISQPG----QPQNEGQPPVTT-LLSQQMPENS--PLASSINTNQNI 1435
Score = 64.3 bits (155), Expect = 6e-10
Identities = 186/842 (22%), Positives = 302/842 (35%), Gaps = 105/842 (12%)
Query: 272 TPVAPTSAVSSSGSPASVMTNMRAPSTTGG-----IGINSVTGTSTVNNVNITAVGSFNP 326
TP +P +G P + ++ + S G IG N + GT + N++ S+
Sbjct: 355 TPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSDENSWKS 414
Query: 327 NVTSSM-LGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPN-A 384
M L + N +P + V+ G+ V +G + + P+ A
Sbjct: 415 EAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDV----QPFTYTPDPA 470
Query: 385 AAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPAT--EGV 442
AAG +V + P S E K T +K N +P +
Sbjct: 471 AAGALNVNVKKEISSPA----------RPCSFEEAMKAMKTTGCNLDKVNIIPNALMTPL 520
Query: 443 LINKVVETVKQNPIEVTSERESTS----GSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQ 498
+ + ++++ P+EVT+E+ S++ SV S+ TL + + G+G +P+
Sbjct: 521 IPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSSSHLP 580
Query: 499 QQQQQQQQQQQPALQGVTL---QQMDFGSTGPQSIPAVSIPQSISQSQ-ISQVQLQSQEL 554
+ ++QQQ Q A TL Q D G + PAVS + S + Q Q Q
Sbjct: 581 SENEKQQQIQPKAYNPETLTTIQTQDISQPG--TFPAVSASSQLPNSDALLQQATQFQTR 638
Query: 555 SYQQKQGLQP----VPLQATMSAATGIQPSPVNVVGVTSALGQQ------PSISSLAQPQ 604
Q ++ LQ V L A+ Q SP+ T L QQ PS +S++Q Q
Sbjct: 639 ETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQT--LQQQISSNIFPSPNSVSQLQ 696
Query: 605 --LPYSQAAPPVQTPLPGAPPP----QQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQ 658
+ QA + G+ QQ+ QQQ AP ++V + +++ Q
Sbjct: 697 NTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADIFQ 756
Query: 659 QQPILQTAMSSG-----------QPSSAGVGAGTTVIPVA------QPQGIQLPVQPTAV 701
Q +Q+ +S G +P + G +V P + Q Q Q Q
Sbjct: 757 QVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQVMES 816
Query: 702 PAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPS 761
A Q + QA A + + S + G P QQ S + +
Sbjct: 817 SAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPV-YQQTSHMMSALSTNEDMQMQ 875
Query: 762 SQVV--PPAQTGIIHQGVQTSAPSLPQQLVIASQSS---LLTVPPQPQGVEPVAQGIVSQ 816
++ PPA +G T + P + + SS T Q V Q +V
Sbjct: 876 CELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQM 935
Query: 817 QLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPP 876
Q + P + S T + S SG L N + + Q+GN +Q S
Sbjct: 936 QHSG-DNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGN--EMMSLQSGNFLQQSSHSQ 992
Query: 877 LIATNTNLPLAQQIPLSS-TQFSA-QSLAQAIGSQIED-ARRAAEPSLVGLPQTISGDSG 933
+ P+A LS TQ S S + SQ + +P + TI+ G
Sbjct: 993 AQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQG 1052
Query: 934 GMSAVSDGSSSSLAASASLFPLKVLPLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKS 993
S D S+++ S S P+ + + + + + A N I S
Sbjct: 1053 S-SVPQDQQSTNIFLSQS-----------PMNNLQTNTVAQEAFFAAPNSISPLQSTSNS 1100
Query: 994 HLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQ 1053
A +++ + Q L ++ +Q P Q FQ Q+ GS P
Sbjct: 1101 EQQAAFQQQAPISHIQTPMLSQEQAQ-------------PPQQGLFQPQVALGSLPPNPM 1147
Query: 1054 PQ 1055
PQ
Sbjct: 1148 PQ 1149
Score = 32.3 bits (72), Expect = 2.5
Identities = 85/400 (21%), Positives = 140/400 (35%), Gaps = 44/400 (11%)
Query: 696 VQPTAVPAQPAGASVQPVG-----QAPA-------AVSAVPTGSQIANIGQQANIPTAVQ 743
VQP PA A V +PA A+ A+ T N+ + IP A+
Sbjct: 460 VQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTG--CNLDKVNIIPNALM 517
Query: 744 QPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQP 803
P +P S+I+ +V ++ I + + S S Q L S + P
Sbjct: 518 TPL--IPSSMIKSEDVTPMEVTAEKRSSTIFKTTK-SVGSTQQTLENISNIAGNGSFSSP 574
Query: 804 QGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQ---- 859
++ QQ+ + P + T +S G SA + L + Q
Sbjct: 575 SSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQ 634
Query: 860 --TPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAA 917
T TQ+ ++QS ++ T +QQ S Q AQ+L Q I S I + +
Sbjct: 635 FQTRETQSREILQSDGTVVNLSQLTEA--SQQQQQSPLQEQAQTLQQQISSNIFPSPNSV 692
Query: 918 EPSLVGLPQ---------TISGDSGGMSAVSDGSSSSLAASASLFPLK------VLPLTT 962
+ Q T SG SG + V + S+ LF L+
Sbjct: 693 SQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSA 752
Query: 963 PLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQ 1022
+ + SG S + + E + +L+ E V E ++ Q +Q
Sbjct: 753 DIFQQVSQIQSGVSP-GMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQ 811
Query: 1023 ---ENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQ 1059
E++ + + + Q AQ+Q+ P+T G Q
Sbjct: 812 QVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQ 851
>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
sapiens]
Length = 1531
Score = 69.7 bits (169), Expect = 1e-11
Identities = 123/477 (25%), Positives = 187/477 (39%), Gaps = 83/477 (17%)
Query: 382 PNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEG 441
PN + SS+Q QP + S+ + L SS P ++ + ++
Sbjct: 1096 PNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQD----------QQSTNIFLSQS 1145
Query: 442 VLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQ 501
+ N TV Q E + +S+S ST + +E + + AP + Q
Sbjct: 1146 PMNNLQTNTVAQ-------EAFFAAPNSISPLQSTSN--SEQQAAFQQQAP--ISHIQTP 1194
Query: 502 QQQQQQQQPALQGVTLQQMDFGSTGPQSIP------------AVSIPQSISQSQISQVQL 549
Q+Q QP QG+ Q+ GS P +P ++ QS S SQ Q Q
Sbjct: 1195 MLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQ 1254
Query: 550 QSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQ 609
Q Q+ QQ+Q Q TM+ + P N++ + Q P + Q Q + Q
Sbjct: 1255 QQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPN---QNPMANQEQQNQSIFHQ 1311
Query: 610 AAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSS 669
Q+ + QQ Q Q VS+ PG TQ+ +S+ Q +
Sbjct: 1312 -----QSNMAPMNQEQQPMQFQSQSTVSSLQNPG----PTQSESSQTPLFHSSPQIQLVQ 1362
Query: 670 GQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAP--AAVSAVPTGS 727
G PSS Q Q + L + P ++ A + Q + Q+P + + +P G
Sbjct: 1363 GSPSS-------------QEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMP-GI 1408
Query: 728 QIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQ-------TS 780
Q A Q P A +T Q +P SSQ +G+ G+Q TS
Sbjct: 1409 QGATSSPQ---PQATLFHNTAGGTMNQLQNSPGSSQ----QTSGMFLFGIQNNCSQLLTS 1461
Query: 781 AP-SLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQV 836
P +LP QL+ SQ PQ +G PV ++SQQ+P S P ASSI+ +
Sbjct: 1462 GPATLPDQLMAISQPG----QPQNEGQPPVTT-LLSQQMPENS--PLASSINTNQNI 1511
Score = 64.3 bits (155), Expect = 6e-10
Identities = 186/842 (22%), Positives = 302/842 (35%), Gaps = 105/842 (12%)
Query: 272 TPVAPTSAVSSSGSPASVMTNMRAPSTTGG-----IGINSVTGTSTVNNVNITAVGSFNP 326
TP +P +G P + ++ + S G IG N + GT + N++ S+
Sbjct: 431 TPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSDENSWKS 490
Query: 327 NVTSSM-LGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPN-A 384
M L + N +P + V+ G+ V +G + + P+ A
Sbjct: 491 EAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDV----QPFTYTPDPA 546
Query: 385 AAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPAT--EGV 442
AAG +V + P S E K T +K N +P +
Sbjct: 547 AAGALNVNVKKEISSPA----------RPCSFEEAMKAMKTTGCNLDKVNIIPNALMTPL 596
Query: 443 LINKVVETVKQNPIEVTSERESTS----GSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQ 498
+ + ++++ P+EVT+E+ S++ SV S+ TL + + G+G +P+
Sbjct: 597 IPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSSSHLP 656
Query: 499 QQQQQQQQQQQPALQGVTL---QQMDFGSTGPQSIPAVSIPQSISQSQ-ISQVQLQSQEL 554
+ ++QQQ Q A TL Q D G + PAVS + S + Q Q Q
Sbjct: 657 SENEKQQQIQPKAYNPETLTTIQTQDISQPG--TFPAVSASSQLPNSDALLQQATQFQTR 714
Query: 555 SYQQKQGLQP----VPLQATMSAATGIQPSPVNVVGVTSALGQQ------PSISSLAQPQ 604
Q ++ LQ V L A+ Q SP+ T L QQ PS +S++Q Q
Sbjct: 715 ETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQT--LQQQISSNIFPSPNSVSQLQ 772
Query: 605 --LPYSQAAPPVQTPLPGAPPP----QQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQ 658
+ QA + G+ QQ+ QQQ AP ++V + +++ Q
Sbjct: 773 NTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADIFQ 832
Query: 659 QQPILQTAMSSG-----------QPSSAGVGAGTTVIPVA------QPQGIQLPVQPTAV 701
Q +Q+ +S G +P + G +V P + Q Q Q Q
Sbjct: 833 QVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQVMES 892
Query: 702 PAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPS 761
A Q + QA A + + S + G P QQ S + +
Sbjct: 893 SAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPV-YQQTSHMMSALSTNEDMQMQ 951
Query: 762 SQVV--PPAQTGIIHQGVQTSAPSLPQQLVIASQSS---LLTVPPQPQGVEPVAQGIVSQ 816
++ PPA +G T + P + + SS T Q V Q +V
Sbjct: 952 CELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQM 1011
Query: 817 QLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPP 876
Q + P + S T + S SG L N + + Q+GN +Q S
Sbjct: 1012 QHSG-DNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGN--EMMSLQSGNFLQQSSHSQ 1068
Query: 877 LIATNTNLPLAQQIPLSS-TQFSA-QSLAQAIGSQIED-ARRAAEPSLVGLPQTISGDSG 933
+ P+A LS TQ S S + SQ + +P + TI+ G
Sbjct: 1069 AQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQG 1128
Query: 934 GMSAVSDGSSSSLAASASLFPLKVLPLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKS 993
S D S+++ S S P+ + + + + + A N I S
Sbjct: 1129 S-SVPQDQQSTNIFLSQS-----------PMNNLQTNTVAQEAFFAAPNSISPLQSTSNS 1176
Query: 994 HLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQ 1053
A +++ + Q L ++ +Q P Q FQ Q+ GS P
Sbjct: 1177 EQQAAFQQQAPISHIQTPMLSQEQAQ-------------PPQQGLFQPQVALGSLPPNPM 1223
Query: 1054 PQ 1055
PQ
Sbjct: 1224 PQ 1225
Score = 32.3 bits (72), Expect = 2.5
Identities = 85/400 (21%), Positives = 140/400 (35%), Gaps = 44/400 (11%)
Query: 696 VQPTAVPAQPAGASVQPVG-----QAPA-------AVSAVPTGSQIANIGQQANIPTAVQ 743
VQP PA A V +PA A+ A+ T N+ + IP A+
Sbjct: 536 VQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTG--CNLDKVNIIPNALM 593
Query: 744 QPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQP 803
P +P S+I+ +V ++ I + + S S Q L S + P
Sbjct: 594 TPL--IPSSMIKSEDVTPMEVTAEKRSSTIFKTTK-SVGSTQQTLENISNIAGNGSFSSP 650
Query: 804 QGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQ---- 859
++ QQ+ + P + T +S G SA + L + Q
Sbjct: 651 SSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQ 710
Query: 860 --TPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAA 917
T TQ+ ++QS ++ T +QQ S Q AQ+L Q I S I + +
Sbjct: 711 FQTRETQSREILQSDGTVVNLSQLTEA--SQQQQQSPLQEQAQTLQQQISSNIFPSPNSV 768
Query: 918 EPSLVGLPQ---------TISGDSGGMSAVSDGSSSSLAASASLFPLK------VLPLTT 962
+ Q T SG SG + V + S+ LF L+
Sbjct: 769 SQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSA 828
Query: 963 PLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQ 1022
+ + SG S + + E + +L+ E V E ++ Q +Q
Sbjct: 829 DIFQQVSQIQSGVSP-GMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQ 887
Query: 1023 ---ENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQ 1059
E++ + + + Q AQ+Q+ P+T G Q
Sbjct: 888 QVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQ 927
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.120 0.329
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,489,988
Number of Sequences: 37866
Number of extensions: 2663417
Number of successful extensions: 33546
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 446
Number of HSP's successfully gapped in prelim test: 1271
Number of HSP's that attempted gapping in prelim test: 16378
Number of HSP's gapped (non-prelim): 11767
length of query: 1073
length of database: 18,247,518
effective HSP length: 113
effective length of query: 960
effective length of database: 13,968,660
effective search space: 13409913600
effective search space used: 13409913600
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.