Guide to the Human Genome
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Search of human proteins with 171184421

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|171184421 thioredoxin interacting protein [Homo sapiens]
         (391 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|171184421 thioredoxin interacting protein [Homo sapiens]           793   0.0  
gi|190886442 arrestin domain containing 4 [Homo sapiens]              336   2e-92
gi|32698736 arrestin domain containing 3 [Homo sapiens]               308   5e-84
gi|18373305 arrestin domain containing 2 isoform 1 [Homo sapiens]     261   1e-69
gi|71040100 arrestin domain containing 2 isoform 2 [Homo sapiens]     253   2e-67
gi|22748653 arrestin domain containing 1 [Homo sapiens]                82   1e-15
gi|122937478 arrestin domain containing 5 [Homo sapiens]               45   1e-04
gi|113865883 WD repeat domain 38 [Homo sapiens]                        30   2.9  
gi|210147507 lipopolysaccharide-induced TNF-alpha factor isoform...    30   3.7  
gi|210147505 lipopolysaccharide-induced TNF-alpha factor isoform...    30   3.7  
gi|65787265 lipopolysaccharide-induced TNF-alpha factor isoform ...    30   3.7  
gi|4505195 mitogen-activated protein kinase kinase kinase 11 [Ho...    30   3.7  
gi|61676089 hypothetical protein LOC222584 [Homo sapiens]              30   4.9  
gi|158303333 synaptopodin isoform B [Homo sapiens]                     29   6.4  
gi|40353727 synaptopodin isoform A [Homo sapiens]                      29   6.4  
gi|57863253 zinc finger protein 500 [Homo sapiens]                     29   6.4  
gi|221139926 NHS-like 1 [Homo sapiens]                                 29   8.3  

>gi|171184421 thioredoxin interacting protein [Homo sapiens]
          Length = 391

 Score =  793 bits (2048), Expect = 0.0
 Identities = 391/391 (100%), Positives = 391/391 (100%)

Query: 1   MVMFKKIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGS 60
           MVMFKKIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGS
Sbjct: 1   MVMFKKIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGS 60

Query: 61  QQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGC 120
           QQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGC
Sbjct: 61  QQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGC 120

Query: 121 VDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCMFIPDGRVSV 180
           VDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCMFIPDGRVSV
Sbjct: 121 VDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCMFIPDGRVSV 180

Query: 181 SARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKLSSVRGN 240
           SARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKLSSVRGN
Sbjct: 181 SARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKLSSVRGN 240

Query: 241 HIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIGSRS 300
           HIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIGSRS
Sbjct: 241 HIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIGSRS 300

Query: 301 GLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQD 360
           GLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQD
Sbjct: 301 GLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQD 360

Query: 361 SPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ 391
           SPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ
Sbjct: 361 SPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ 391


>gi|190886442 arrestin domain containing 4 [Homo sapiens]
          Length = 418

 Score =  336 bits (862), Expect = 2e-92
 Identities = 179/394 (45%), Positives = 250/394 (63%), Gaps = 22/394 (5%)

Query: 6   KIKSFEVVFNDPEK-VYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGSQQCK 64
           ++KS  +VF D  K  Y SGE VAG V++E  E   ++A+R+ A G A   W  G   C 
Sbjct: 16  RVKSLGLVFEDERKGCYSSGETVAGHVLLEASEPVALRALRLEAQGRATAAW--GPSTCP 73

Query: 65  QTS------------EYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGT 112
           + S            EYL     L L + P GE  +++++PG K+E+ F F+LP  PL T
Sbjct: 74  RASASTAALAVFSEVEYLNVR--LSLREPPAGEG-IILLQPG-KHEFPFRFQLPSEPLVT 129

Query: 113 SFKGKYGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCMF 172
           SF GKYG + Y V+A L+RP  P Q  K+  +VV  VDVNTP L+ PV   +EK V C F
Sbjct: 130 SFTGKYGSIQYCVRAVLERPKVPDQSVKRELQVVSHVDVNTPALLTPVLKTQEKMVGCWF 189

Query: 173 IPDGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQ 232
              G VS+SA+I+RKG+C G+ I I+A+ EN  SR++VPKAAI    TYLA+G+TK +  
Sbjct: 190 FTSGPVSLSAKIERKGYCNGEAIPIYAEIENCSSRLIVPKAAIFQTQTYLASGKTKTIRH 249

Query: 233 KLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDL 292
            +++VRGNHI SG+  +W GK+L++  + PSIL C I+RV+YSL +Y+ +PG+KK++L+L
Sbjct: 250 MVANVRGNHIASGSTDTWNGKTLKIPPVTPSILDCCIIRVDYSLAVYIHIPGAKKLMLEL 309

Query: 293 PLVIGS--RSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDH-RLESPTT 349
           PLVIG+   +G  SR SS+AS+ S +MSW+ L +P+ PEAPP Y DV+ E+      P  
Sbjct: 310 PLVIGTIPYNGFGSRNSSIASQFSMDMSWLTLTLPEQPEAPPNYADVVSEEEFSRHIPPY 369

Query: 350 PLLDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDP 383
           P   + +G    P+F    EF+F PPP Y+EVDP
Sbjct: 370 PQPPNCEGEVCCPVFACIQEFRFQPPPLYSEVDP 403


>gi|32698736 arrestin domain containing 3 [Homo sapiens]
          Length = 414

 Score =  308 bits (789), Expect = 5e-84
 Identities = 166/396 (41%), Positives = 242/396 (61%), Gaps = 19/396 (4%)

Query: 6   KIKSFEVVF---NDPE-KVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQG-- 59
           K+KS  + F   ND    VY SG+ V+GRV +EV    RVK+++I A G AKV W +   
Sbjct: 5   KVKSLTISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRN 64

Query: 60  -------SQQCKQTSEYLRYEDTLL--LEDQPTGENEMVIMRPGNKYEYKFGFELPQGPL 110
                  +Q   +  EY  ++D L+    D    E     +  G ++EY F FELPQ PL
Sbjct: 65  AGSNTAYTQNYTEEVEYFNHKDILIGHERDDDNSEEGFHTIHSG-RHEYAFSFELPQTPL 123

Query: 111 GTSFKGKYGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSC 170
            TSF+G++G V YWVKA L RP     + KK F V + +D+NTP L++P +  KEK + C
Sbjct: 124 ATSFEGRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDINTPSLLSPQAGTKEKTLCC 183

Query: 171 MFIPDGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVL 230
            F   G +S+SA+I+RKG+  G+ I I A+ EN  SR+VVPKAAI     + A G+ K +
Sbjct: 184 WFCTSGPISLSAKIERKGYTPGESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKGKMKEV 243

Query: 231 TQKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVIL 290
            Q ++++RG  + SG   +W GK L++  + PSIL C+I+RVEYSL++YV +PG+  + L
Sbjct: 244 KQLVANLRGESLSSGKTETWNGKLLKIPPVSPSILDCSIIRVEYSLMVYVDIPGAMDLFL 303

Query: 291 DLPLVIGS--RSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLES-P 347
           +LPLVIG+       SRTSS++S+ S  M+W+ L++P+ PEAPP Y +V+ E+ R  +  
Sbjct: 304 NLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLSLSLPERPEAPPSYAEVVTEEQRRNNLA 363

Query: 348 TTPLLDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDP 383
                DD + +   P+F Y  EF+F+PPP Y+E+DP
Sbjct: 364 PVSACDDFERALQGPLFAYIQEFRFLPPPLYSEIDP 399


>gi|18373305 arrestin domain containing 2 isoform 1 [Homo sapiens]
          Length = 407

 Score =  261 bits (666), Expect = 1e-69
 Identities = 152/399 (38%), Positives = 230/399 (57%), Gaps = 23/399 (5%)

Query: 2   VMFKKIKSFEVVFNDP----EKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWM 57
           ++F K+K+F V  +      E V+  G+ VAGRV++E+    RV A+R+ A G A V W 
Sbjct: 1   MLFDKVKAFSVQLDGATAGVEPVFSGGQAVAGRVLLELSSAARVGALRLRARGRAHVHWT 60

Query: 58  QG---------SQQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQG 108
           +          +Q   +  E + +  TLL  D  TGE   +   P  ++E+ F F+LP  
Sbjct: 61  ESRSAGSSTAYTQSYSERVEVVSHRATLLAPD--TGETTTL---PPGRHEFLFSFQLPP- 114

Query: 109 PLGTSFKGKYGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKV 168
            L TSF+GK+G V Y +KA L RP  P +  +K F V++ VD+NTP L+AP +  +EK  
Sbjct: 115 TLVTSFEGKHGSVRYCIKATLHRPWVPARRARKVFTVIEPVDINTPALLAPQAGAREKVA 174

Query: 169 SCMFIPDGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTK 228
              +   G VS+SA+IDRKG+  G+ I + A+ +N  +R V+P+AA+V   T++A G  K
Sbjct: 175 RSWYCNRGLVSLSAKIDRKGYTPGEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGARK 234

Query: 229 VLTQKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKV 288
                ++S+ G  +  G  A W+G++LR+  + PSIL C +L V+Y+L + V +PG+ K+
Sbjct: 235 QKRAVVASLAGEPVGPGQRALWQGRALRIPPVGPSILHCRVLHVDYALKVCVDIPGTSKL 294

Query: 289 ILDLPLVIGS--RSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVI--PEDHRL 344
           +L+LPLVIG+       SR+SS+ S  S  + W    +P+ PEAPP Y +V+   E+  L
Sbjct: 295 LLELPLVIGTIPLHPFGSRSSSVGSHASFLLDWRLGALPERPEAPPEYSEVVADTEEAAL 354

Query: 345 ESPTTPLLDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDP 383
                PL  D D S + P F Y  EF++ PPP Y+E DP
Sbjct: 355 GQSPFPLPQDPDMSLEGPFFAYIQEFRYRPPPLYSEEDP 393


>gi|71040100 arrestin domain containing 2 isoform 2 [Homo sapiens]
          Length = 402

 Score =  253 bits (646), Expect = 2e-67
 Identities = 147/390 (37%), Positives = 222/390 (56%), Gaps = 20/390 (5%)

Query: 7   IKSFEV-VFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQG------ 59
           ++SF + +   P   Y  GE++ GRV++E     RV+A+ + A G A   W++G      
Sbjct: 6   VRSFALELARGPGGAYRGGERLCGRVLLEAAAPLRVRALEVKARGGAATHWLEGRSVGVN 65

Query: 60  --SQQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGK 117
             S        YLR    LL +   TGE   +   P  ++E+ F F+LP   L TSF+GK
Sbjct: 66  AVSSDYAAAETYLRRRQLLLRD---TGETTTL---PPGRHEFLFSFQLPP-TLVTSFEGK 118

Query: 118 YGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCMFIPDGR 177
           +G V Y +KA L RP  P +  +K F V++ VD+NTP L+AP +  +EK     +   G 
Sbjct: 119 HGSVRYCIKATLHRPWVPARRARKVFTVIEPVDINTPALLAPQAGAREKVARSWYCNRGL 178

Query: 178 VSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKLSSV 237
           VS+SA+IDRKG+  G+ I + A+ +N  +R V+P+AA+V   T++A G  K     ++S+
Sbjct: 179 VSLSAKIDRKGYTPGEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGARKQKRAVVASL 238

Query: 238 RGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIG 297
            G  +  G  A W+G++LR+  + PSIL C +L V+Y+L + V +PG+ K++L+LPLVIG
Sbjct: 239 AGEPVGPGQRALWQGRALRIPPVGPSILHCRVLHVDYALKVCVDIPGTSKLLLELPLVIG 298

Query: 298 S--RSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVI--PEDHRLESPTTPLLD 353
           +       SR+SS+ S  S  + W    +P+ PEAPP Y +V+   E+  L     PL  
Sbjct: 299 TIPLHPFGSRSSSVGSHASFLLDWRLGALPERPEAPPEYSEVVADTEEAALGQSPFPLPQ 358

Query: 354 DMDGSQDSPIFMYAPEFKFMPPPTYTEVDP 383
           D D S + P F Y  EF++ PPP Y+E DP
Sbjct: 359 DPDMSLEGPFFAYIQEFRYRPPPLYSEEDP 388


>gi|22748653 arrestin domain containing 1 [Homo sapiens]
          Length = 433

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 79/347 (22%), Positives = 155/347 (44%), Gaps = 36/347 (10%)

Query: 6   KIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGSQQCKQ 65
           +++ FE+  +    VY  GE +AG V V +      +A+R+   G   V     S +   
Sbjct: 3   RVQLFEISLSHGRVVYSPGEPLAGTVRVRLGAPLPFRAIRVTCIGSCGV-----SNKAND 57

Query: 66  TSEYLR---YEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVD 122
           T+  +    +  +L L D+ +         P  ++ + F F LP     TSF+G +G + 
Sbjct: 58  TAWVVEEGYFNSSLSLADKGS--------LPAGEHSFPFQFLLP-ATAPTSFEGPFGKIV 108

Query: 123 YWVKAFLDRPS-QPTQETKKNFEVVDLVDVNT-PDLMAPVSAKKEKKVSCMFIPDGRVSV 180
           + V+A +  P      +    F ++  +++N+ PD+  P  A   KK S   +  G V +
Sbjct: 109 HQVRAAIHTPRFSKDHKCSLVFYILSPLNLNSIPDIEQPNVASATKKFSYKLVKTGSVVL 168

Query: 181 SARIDRKGFCEGDEISIHADFENTCSRIVVP-KAAIVARHTYLANGQTKVLTQKLSSVRG 239
           +A  D +G+  G  + +HAD EN   +   P  A+++ + +Y A      + + ++ V G
Sbjct: 169 TASTDLRGYVVGQALQLHADVENQSGKDTSPVVASLLQKVSYKAKRWIHDV-RTIAEVEG 227

Query: 240 NHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIGSR 299
             + +   A W  + L     + ++ GC+++ ++Y L + +  P   +  + LP+ IG+ 
Sbjct: 228 AGVKAWRRAQWHEQILVPALPQSALPGCSLIHIDYYLQVSLKAP---EATVTLPVFIGN- 283

Query: 300 SGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLES 346
             ++   + ++ R         L +P  P APP  +   P     E+
Sbjct: 284 --IAVNHAPVSPRPG-------LGLP--PGAPPLVVPSAPPQEEAEA 319


>gi|122937478 arrestin domain containing 5 [Homo sapiens]
          Length = 342

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 48/228 (21%), Positives = 95/228 (41%), Gaps = 27/228 (11%)

Query: 7   IKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGSQQ---- 62
           +KS E+V  + +++Y +G  + G+VI+ +        V++   G   V W + +      
Sbjct: 18  VKSIELVLPE-DRIYLAGSSIKGQVILTLNSTLVDPIVKVELVGRGYVEWSEEAGASCDY 76

Query: 63  -----CKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGK 117
                C   ++Y+    T  +ED                + + F F LP   L ++F  K
Sbjct: 77  SRNVICNNKADYVHKTKTFPVEDN---------WLSAGSHTFDFHFNLPP-RLPSTFTSK 126

Query: 118 YGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDV---NTPDLMAPVSAKKEKKVSCMFIP 174
           +G V Y+V+A      +     K+ + +V         TP    P+  + E+KVS     
Sbjct: 127 FGHVFYFVQASC-MGREHILAKKRMYLLVQGTSTFHKETP-FQNPLFVEAEEKVSYNCCR 184

Query: 175 DGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYL 222
            G V +  +++R  F  G+++    +  N  S+ +  K  + A + ++
Sbjct: 185 QGTVCLQIQMERNTFTPGEKVVFTTEINNQTSKCI--KTVVFALYAHI 230


>gi|113865883 WD repeat domain 38 [Homo sapiens]
          Length = 314

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 16/63 (25%), Positives = 28/63 (44%)

Query: 124 WVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCMFIPDGRVSVSAR 183
           WVK+    P +    +     +V + D NT   +  +    +   +C F PDG++ VS  
Sbjct: 235 WVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTCAFTPDGKILVSGA 294

Query: 184 IDR 186
            D+
Sbjct: 295 ADQ 297


>gi|210147507 lipopolysaccharide-induced TNF-alpha factor isoform 2
           [Homo sapiens]
          Length = 152

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 18/62 (29%), Positives = 26/62 (41%), Gaps = 6/62 (9%)

Query: 328 PEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILN 387
           P APP Y + +  +    +P  P+     G       +  P+ K M PP+Y      I N
Sbjct: 17  PSAPPSYEETVAVNSYYPTPPAPMPGPTTG------LVTGPDGKGMNPPSYYTQPAPIPN 70

Query: 388 NN 389
           NN
Sbjct: 71  NN 72


>gi|210147505 lipopolysaccharide-induced TNF-alpha factor isoform 1
           [Homo sapiens]
          Length = 161

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 18/62 (29%), Positives = 26/62 (41%), Gaps = 6/62 (9%)

Query: 328 PEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILN 387
           P APP Y + +  +    +P  P+     G       +  P+ K M PP+Y      I N
Sbjct: 17  PSAPPSYEETVAVNSYYPTPPAPMPGPTTG------LVTGPDGKGMNPPSYYTQPAPIPN 70

Query: 388 NN 389
           NN
Sbjct: 71  NN 72


>gi|65787265 lipopolysaccharide-induced TNF-alpha factor isoform 1
           [Homo sapiens]
          Length = 161

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 18/62 (29%), Positives = 26/62 (41%), Gaps = 6/62 (9%)

Query: 328 PEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILN 387
           P APP Y + +  +    +P  P+     G       +  P+ K M PP+Y      I N
Sbjct: 17  PSAPPSYEETVAVNSYYPTPPAPMPGPTTG------LVTGPDGKGMNPPSYYTQPAPIPN 70

Query: 388 NN 389
           NN
Sbjct: 71  NN 72


>gi|4505195 mitogen-activated protein kinase kinase kinase 11 [Homo
           sapiens]
          Length = 847

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 32/118 (27%), Positives = 44/118 (37%), Gaps = 12/118 (10%)

Query: 274 YSLLIYVSVPGSKKVILDLPLVIGSRSGLSSR--------TSSMASRTSSEMSWVDLNIP 325
           +SL    S P    ++LDL + +G RS  S R        T S    TS          P
Sbjct: 698 FSLKTPDSPPTPAPLLLDLGIPVGQRSAKSPRREEEPRGGTVSPPPGTSRSAP----GTP 753

Query: 326 DTPEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDP 383
            TP +PP  +   P    L S   P      G + SP+    P  +  P   + + DP
Sbjct: 754 GTPRSPPLGLISRPRPSPLRSRIDPWSFVSAGPRPSPLPSPQPAPRRAPWTLFPDSDP 811


>gi|61676089 hypothetical protein LOC222584 [Homo sapiens]
          Length = 1011

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 30/126 (23%), Positives = 51/126 (40%), Gaps = 13/126 (10%)

Query: 64  KQTSEYLRYEDTLLLEDQ--PTGENEMVIMRPGNKYEYKFGF---------ELPQGPLGT 112
           KQT      +   LL+ +  P  +N    + PGN   Y +           E P+  L  
Sbjct: 646 KQTENLKNQQTENLLKRRSFPLFDNSKANLDPGNSKHYVYSTLTRNRVRQPEKPKEDLLK 705

Query: 113 SFKGKYGCVDYWVK--AFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSC 170
           S K  +       +    + + + P+  T K+  +  L+DVN  +    +++KKE K S 
Sbjct: 706 SSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSP 765

Query: 171 MFIPDG 176
            F+  G
Sbjct: 766 SFLKKG 771


>gi|158303333 synaptopodin isoform B [Homo sapiens]
          Length = 685

 Score = 29.3 bits (64), Expect = 6.4
 Identities = 17/50 (34%), Positives = 21/50 (42%)

Query: 331 PPCYMDVIPEDHRLESPTTPLLDDMDGSQDSPIFMYAPEFKFMPPPTYTE 380
           PP   D  P   R     +P+++     Q SP     P   F  PPTYTE
Sbjct: 274 PPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTE 323


>gi|40353727 synaptopodin isoform A [Homo sapiens]
          Length = 903

 Score = 29.3 bits (64), Expect = 6.4
 Identities = 17/50 (34%), Positives = 21/50 (42%)

Query: 331 PPCYMDVIPEDHRLESPTTPLLDDMDGSQDSPIFMYAPEFKFMPPPTYTE 380
           PP   D  P   R     +P+++     Q SP     P   F  PPTYTE
Sbjct: 274 PPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTE 323


>gi|57863253 zinc finger protein 500 [Homo sapiens]
          Length = 480

 Score = 29.3 bits (64), Expect = 6.4
 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 10/82 (12%)

Query: 293 PLVIGSRSGLSSRTSSMASRTSSEMSW--VDLNIPDTP-----EAPPCYMDVIPEDHRLE 345
           PL+   R   + R   MAS +    +W  V +N+ D       E P C MD    D  LE
Sbjct: 193 PLLWPERGPPAPRHQEMASASPFLSAWSQVPVNLEDVAVYLSGEEPRC-MDPAQRDAPLE 251

Query: 346 S--PTTPLLDDMDGSQDSPIFM 365
           +  P   L D  DG +D+P+ M
Sbjct: 252 NEGPGIQLEDGGDGREDAPLRM 273


>gi|221139926 NHS-like 1 [Homo sapiens]
          Length = 1606

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 28/97 (28%), Positives = 38/97 (39%), Gaps = 9/97 (9%)

Query: 282 VPGSKKVILDLPLVIGSRSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVI--P 339
           VP  K  ++    +  S + LSS TS+  S T  ++    +  P  P  PP        P
Sbjct: 885 VPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLD-PAVGSPPAPPPPPVPSPPFPCP 943

Query: 340 EDHRLESPTTPLLDDMDGSQDSPIFMYAPEFKFMPPP 376
            D     P  P + D   SQ SP+    P     PPP
Sbjct: 944 ADRSPFLPPPPPVTDC--SQGSPL----PHSPVFPPP 974


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,169,861
Number of Sequences: 37866
Number of extensions: 741094
Number of successful extensions: 1678
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1649
Number of HSP's gapped (non-prelim): 20
length of query: 391
length of database: 18,247,518
effective HSP length: 104
effective length of query: 287
effective length of database: 14,309,454
effective search space: 4106813298
effective search space used: 4106813298
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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