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Search of human proteins with 170650661
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1
[Homo sapiens]
(925 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1 ... 1954 0.0
gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3 ... 957 0.0
gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens] 762 0.0
gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens] 754 0.0
gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens] 738 0.0
gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4 (p... 250 5e-66
gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5 (... 241 3e-63
gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6 [... 199 1e-50
gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7 [... 186 1e-46
gi|239755573 PREDICTED: similar to ectonucleotide pyrophosphatas... 82 2e-15
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 53 1e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 53 1e-06
gi|209969800 RPE-spondin [Homo sapiens] 47 6e-05
gi|5174623 placental protein 11 precursor [Homo sapiens] 46 1e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 45 4e-04
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 45 4e-04
gi|169217659 PREDICTED: similar to ectonucleotide pyrophosphatas... 41 0.005
gi|169167316 PREDICTED: similar to ectonucleotide pyrophosphatas... 41 0.005
gi|10092665 sushi domain containing 2 [Homo sapiens] 39 0.022
gi|224451073 endo/exonuclease (5'-3'), endonuclease G-like isofo... 39 0.029
gi|239749375 PREDICTED: hypothetical protein XP_002347018 [Homo ... 39 0.029
gi|239743512 PREDICTED: hypothetical protein XP_002342879 [Homo ... 39 0.029
gi|88853069 vitronectin precursor [Homo sapiens] 38 0.050
gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens] 38 0.050
gi|239756937 PREDICTED: hypothetical protein [Homo sapiens] 37 0.11
gi|239751449 PREDICTED: hypothetical protein XP_002347867 [Homo ... 37 0.11
gi|239745954 PREDICTED: hypothetical protein XP_002343623 [Homo ... 37 0.11
gi|224451075 endo/exonuclease (5'-3'), endonuclease G-like isofo... 36 0.14
gi|194363768 homeobox D9 [Homo sapiens] 36 0.14
gi|239743493 PREDICTED: hypothetical protein XP_002342862 [Homo ... 36 0.14
>gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1
[Homo sapiens]
Length = 925
Score = 1954 bits (5063), Expect = 0.0
Identities = 925/925 (100%), Positives = 925/925 (100%)
Query: 1 MERDGCAGGGSRGGEGGRAPREGPAGNGRDRGRSHAAEAPGDPQAAASLLAPMDVGEEPL 60
MERDGCAGGGSRGGEGGRAPREGPAGNGRDRGRSHAAEAPGDPQAAASLLAPMDVGEEPL
Sbjct: 1 MERDGCAGGGSRGGEGGRAPREGPAGNGRDRGRSHAAEAPGDPQAAASLLAPMDVGEEPL 60
Query: 61 EKAARARTAKDPNTYKVLSLVLSVCVLTTILGCIFGLKPSCAKEVKSCKGRCFERTFGNC 120
EKAARARTAKDPNTYKVLSLVLSVCVLTTILGCIFGLKPSCAKEVKSCKGRCFERTFGNC
Sbjct: 61 EKAARARTAKDPNTYKVLSLVLSVCVLTTILGCIFGLKPSCAKEVKSCKGRCFERTFGNC 120
Query: 121 RCDAACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSLCACSDDCKDKGDCCINY 180
RCDAACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSLCACSDDCKDKGDCCINY
Sbjct: 121 RCDAACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSLCACSDDCKDKGDCCINY 180
Query: 181 SSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKK 240
SSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKK
Sbjct: 181 SSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKK 240
Query: 241 CGTYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEW 300
CGTYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEW
Sbjct: 241 CGTYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEW 300
Query: 301 YKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLP 360
YKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLP
Sbjct: 301 YKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLP 360
Query: 361 KDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLIL 420
KDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLIL
Sbjct: 361 KDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLIL 420
Query: 421 ISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSC 480
ISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSC
Sbjct: 421 ISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSC 480
Query: 481 REPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNV 540
REPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNV
Sbjct: 481 REPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNV 540
Query: 541 FSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLLKNPVY 600
FSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLLKNPVY
Sbjct: 541 FSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLLKNPVY 600
Query: 601 TPKHPKEVHPLVQCPFTRNPRDNLGCSCNPSILPIEDFQTQFNLTVAEEKIIKHETLPYG 660
TPKHPKEVHPLVQCPFTRNPRDNLGCSCNPSILPIEDFQTQFNLTVAEEKIIKHETLPYG
Sbjct: 601 TPKHPKEVHPLVQCPFTRNPRDNLGCSCNPSILPIEDFQTQFNLTVAEEKIIKHETLPYG 660
Query: 661 RPRVLQKENTICLLSQHQFMSGYSQDILMPLWTSYTVDRNDSFSTEDFSNCLYQDFRIPL 720
RPRVLQKENTICLLSQHQFMSGYSQDILMPLWTSYTVDRNDSFSTEDFSNCLYQDFRIPL
Sbjct: 661 RPRVLQKENTICLLSQHQFMSGYSQDILMPLWTSYTVDRNDSFSTEDFSNCLYQDFRIPL 720
Query: 721 SPVHKCSFYKNNTKVSYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFHDTL 780
SPVHKCSFYKNNTKVSYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFHDTL
Sbjct: 721 SPVHKCSFYKNNTKVSYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFHDTL 780
Query: 781 LRKYAEERNGVNVVSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKD 840
LRKYAEERNGVNVVSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKD
Sbjct: 781 LRKYAEERNGVNVVSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKD 840
Query: 841 TSQTPLHCENLDTLAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSF 900
TSQTPLHCENLDTLAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSF
Sbjct: 841 TSQTPLHCENLDTLAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSF 900
Query: 901 YQQRKEPVSDILKLKTHLPTFSQED 925
YQQRKEPVSDILKLKTHLPTFSQED
Sbjct: 901 YQQRKEPVSDILKLKTHLPTFSQED 925
>gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3
[Homo sapiens]
Length = 875
Score = 957 bits (2474), Expect = 0.0
Identities = 458/856 (53%), Positives = 593/856 (69%), Gaps = 14/856 (1%)
Query: 75 YKVLSLVLSVCVLTTILGCIFGLKPSCAKEVKSCKGRCFERTFG---NCRCDAACVELGN 131
YK+ +VL ++ LG GL ++ SC+ +CF+ +F NCRCD AC + G+
Sbjct: 21 YKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFDASFRGLENCRCDVACKDRGD 80
Query: 132 CCLDYQETCIEPEHIWTCNKFRCGEKRLTRSLCACSDDCKDKGDCCINYSSVCQGEKSWV 191
CC D+++TC+E IW CNKFRCGE RL SLC+CSDDC + DCC +Y SVCQGE SW+
Sbjct: 81 CCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCLQRKDCCADYKSVCQGETSWL 140
Query: 192 EEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTKNMRPV 251
EE C++ + QCP GF+ PP +LFS+DGFRAEYL+TW L+P I+KLK CG ++K MR +
Sbjct: 141 EENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAM 200
Query: 252 YPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAK 311
YPTKTFPNHY+IVTGLYPESHGIIDN MYD +N +FSL SKE+ NP W+ G+P+W+TA
Sbjct: 201 YPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQPMWLTAM 260
Query: 312 YQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLY 371
YQGLK+ T+FWPGS+V ING FP IY YNGSVPFEERI +L+WL LPK ERP FYT+Y
Sbjct: 261 YQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERISTLLKWLDLPKAERPRFYTMY 320
Query: 372 LEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSC 431
EEPDSSGH+ GPVS+ VIKALQ VD GMLM+GLK+ NLH C+N+IL++DHGM+Q C
Sbjct: 321 FEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQTYC 380
Query: 432 KKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHFKPYL 491
K Y+ Y + + GPA R+R ++P ++SFN E I RNLSCR+P+QHFKPYL
Sbjct: 381 NKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYL 440
Query: 492 KHFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNVFSNMQALFVGY 551
LPKRLH+AK+ RI+ + ++D QW LA+ CG G HG +N F +M+A+F+ +
Sbjct: 441 TPDLPKRLHYAKNVRIDKVHLFVDQQW-LAVRSKSNTNCGGGNHGYNNEFRSMEAIFLAH 499
Query: 552 GPGFKHGIEADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLLKNPVYTPKHPKEVHPL 611
GP FK E + FENIEVYNLMCDLL + PAPNNGTHGSLNHLLK P Y P H +EV
Sbjct: 500 GPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLNHLLKVPFYEPSHAEEVSKF 559
Query: 612 VQCPFTRN-PRDNLGCSCN--PSILPIEDFQTQFNLTVAEEKIIKHETLPYGRPRVLQKE 668
C F P ++L C C + +E NLT E LP+GRPRVLQK
Sbjct: 560 SVCGFANPLPTESLDCFCPHLQNSTQLEQVNQMLNLTQEEITATVKVNLPFGRPRVLQKN 619
Query: 669 NTICLLSQHQFMSGYSQDILMPLWTSYTVDR--NDSFSTEDFSNCLYQDFRIPLSPVHKC 726
CLL +++SG+ + + MP+W+SYTV + + S +CL D R+P S KC
Sbjct: 620 VDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPTVPDCLRADVRVPPSESQKC 679
Query: 727 SFYKNNTKVSYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFHDTLLRKYAE 786
SFY + +++GFL PP N+ S Y +AL+T+N+VPMY+ F+ +W YFH LL K+A
Sbjct: 680 SFYLADKNITHGFLYPPASNRTSDSQY-DALITSNLVPMYEEFRKMWDYFHSVLLIKHAT 738
Query: 787 ERNGVNVVSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKDTSQTPL 846
ERNGVNVVSGP+FD++YDG D+ + + + + N ++ IPTH+F+VLTSCK+ S TP
Sbjct: 739 ERNGVNVVSGPIFDYNYDGHFDAPDEITKH---LANTDVPIPTHYFVVLTSCKNKSHTPE 795
Query: 847 HCEN-LDTLAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSFYQQRK 905
+C LD L FI+PHR N ESC GK ++ WVEE H AR+ DVE +TGL FYQ +
Sbjct: 796 NCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRDVELLTGLDFYQDKV 855
Query: 906 EPVSDILKLKTHLPTF 921
+PVS+IL+LKT+LPTF
Sbjct: 856 QPVSEILQLKTYLPTF 871
>gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens]
Length = 863
Score = 762 bits (1967), Expect = 0.0
Identities = 376/831 (45%), Positives = 518/831 (62%), Gaps = 39/831 (4%)
Query: 107 SCKGRCFERTFG---NCRCDAACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSL 163
SCKGRCFE +CRCD C +CC D+ E C++ W C K RCGE R +
Sbjct: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117
Query: 164 CACSDDCKDKGDCCINYSSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAE 223
C CS+DC +GDCC NY VC+GE WV++ CE I +CPAGF PP ++FS+DGFRA
Sbjct: 118 CHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRAS 177
Query: 224 YLHTWGGLLPVISKLKKCGTYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPK 283
Y+ ++P I KL+ CGT++ MRPVYPTKTFPN Y++ TGLYPESHGI+ N MYDP
Sbjct: 178 YMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPV 237
Query: 284 MNASFSLKSKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGS 343
+A+F L+ +EKFN W+ G+P+W+TA QG+K+GTFFW +
Sbjct: 238 FDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SVV 279
Query: 344 VPFEERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGML 403
+P E RIL +LQWL LP ERP Y Y E+PD SGH YGP E+ L+ +D +VG L
Sbjct: 280 IPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQL 339
Query: 404 MDGLKELNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVP 463
MDGLK+L LHRC+N+I + DHGME +C + +L+ YL +V +I ++ G R+R
Sbjct: 340 MDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSN 399
Query: 464 DKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALN 523
+ Y + + I NL+C++P+QHFKPYLK LPKRLH+A + RIE + ++ +W +A
Sbjct: 400 NAKY--DPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARK 457
Query: 524 PSE--RKYCG----SGFHGSDNVFSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLL 577
P + +K G G HG DN ++MQ +FVGYG FK+ + FENIE+YN+MCDLL
Sbjct: 458 PLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLL 517
Query: 578 NLTPAPNNGTHGSLNHLLKNPVYTPKHPKEV-HPLVQCPFTRNPRDNLGCSCNPSILPIE 636
L PAPNNGTHGSLNHLL+ + P P+EV P +LGC+C+ + P +
Sbjct: 518 GLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEP-K 576
Query: 637 DFQTQFNLTVAEEKIIKHETLPYGRPRVLQKENTICLLSQHQFMSGYSQDILMPLWTSYT 696
+ + N + + + L YGRP VL + +L F SGYS+ LMPLWTSYT
Sbjct: 577 NKLDELNKRLHTKGSTEERHLLYGRPAVLYR-TRYDILYHTDFESGYSEIFLMPLWTSYT 635
Query: 697 VDRNDSFST--EDFSNCLYQDFRIPLSPVHKCSFYKNNTKVSYGFLSPPQLNKNSSGIYS 754
V + S+ + ++C+ D R+ S C YKN+ ++SYGFL PP L+ + Y
Sbjct: 636 VSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKY- 694
Query: 755 EALLTTNIVPMYQSFQVIWRYFHDTLLRKYAEERNGVNVVSGPVFDFDYDGRCDSLENLR 814
+A L TN+VPMY +F+ +W YF L++KYA ERNGVNV+SGP+FD+DYDG D+ + ++
Sbjct: 695 DAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIK 754
Query: 815 QKRRVIRNQEILIPTHFFIVLTSCKDTSQTPLHCEN-LDTLAFILPHRTDNSESCVHGKH 873
Q + I +PTH++ ++TSC D +Q C+ L +FILPHR DN ESC +
Sbjct: 755 Q---YVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSED 811
Query: 874 DSSWVEELLMLHRARITDVEHITGLSFYQQRKEPVSDILKLKTHLPTFSQE 924
+S WVEEL+ +H AR+ D+EH+T L F+++ +IL LKT+L T+ E
Sbjct: 812 ESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESE 862
>gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens]
Length = 888
Score = 754 bits (1947), Expect = 0.0
Identities = 379/855 (44%), Positives = 521/855 (60%), Gaps = 62/855 (7%)
Query: 107 SCKGRCFERTFG---NCRCDAACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSL 163
SCKGRCFE +CRCD C +CC D+ E C++ W C K RCGE R +
Sbjct: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117
Query: 164 CACSDDCKDKGDCCINYSSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAE 223
C CS+DC +GDCC NY VC+GE WV++ CE I +CPAGF PP ++FS+DGFRA
Sbjct: 118 CHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRAS 177
Query: 224 YLHTWGGLLPVISKLKKCGTYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPK 283
Y+ ++P I KL+ CGT++ MRPVYPTKTFPN Y++ TGLYPESHGI+ N MYDP
Sbjct: 178 YMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPV 237
Query: 284 MNASFSLKSKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGS 343
+A+F L+ +EKFN W+ G+P+W+TA QG+K+GTFFW +
Sbjct: 238 FDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SVV 279
Query: 344 VPFEERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGML 403
+P E RIL +LQWL LP ERP Y Y E+PD SGH YGP E+ L+ +D +VG L
Sbjct: 280 IPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQL 339
Query: 404 MDGLKELNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVP 463
MDGLK+L LHRC+N+I + DHGME +C + +L+ YL +V +I ++ G R+R
Sbjct: 340 MDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSN 399
Query: 464 DKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALN 523
+ Y + + I NL+C++P+QHFKPYLK LPKRLH+A + RIE + ++ +W +A
Sbjct: 400 NAKY--DPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARK 457
Query: 524 PSE--RKYCG----SGFHGSDNVFSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLL 577
P + +K G G HG DN ++MQ +FVGYG FK+ + FENIE+YN+MCDLL
Sbjct: 458 PLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLL 517
Query: 578 NLTPAPNNGTHGSLNHLLKNPVYTPKHPKEV-HPLVQCPFTRNPRDNLGCSCNPSILP-- 634
L PAPNNGTHGSLNHLL+ + P P+EV P +LGC+C+ + P
Sbjct: 518 GLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKN 577
Query: 635 -IEDFQTQFNL---TVAEEKII------------------KHETLPYGRPRVLQKENTIC 672
+++ + + T AE + K L YGRP VL +
Sbjct: 578 KLDELNKRLHTKGSTEAETRKFRGSRNENKENINGNFEPRKERHLLYGRPAVLYR-TRYD 636
Query: 673 LLSQHQFMSGYSQDILMPLWTSYTVDRNDSFST--EDFSNCLYQDFRIPLSPVHKCSFYK 730
+L F SGYS+ LMPLWTSYTV + S+ + ++C+ D R+ S C YK
Sbjct: 637 ILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYK 696
Query: 731 NNTKVSYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFHDTLLRKYAEERNG 790
N+ ++SYGFL PP L+ + Y +A L TN+VPMY +F+ +W YF L++KYA ERNG
Sbjct: 697 NDKQMSYGFLFPPYLSSSPEAKY-DAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNG 755
Query: 791 VNVVSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKDTSQTPLHCEN 850
VNV+SGP+FD+DYDG D+ + ++Q + I +PTH++ ++TSC D +Q C+
Sbjct: 756 VNVISGPIFDYDYDGLHDTEDKIKQ---YVEGSSIPVPTHYYSIITSCLDFTQPADKCDG 812
Query: 851 -LDTLAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSFYQQRKEPVS 909
L +FILPHR DN ESC + +S WVEEL+ +H AR+ D+EH+T L F+++
Sbjct: 813 PLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYP 872
Query: 910 DILKLKTHLPTFSQE 924
+IL LKT+L T+ E
Sbjct: 873 EILTLKTYLHTYESE 887
>gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens]
Length = 915
Score = 738 bits (1904), Expect = 0.0
Identities = 376/883 (42%), Positives = 518/883 (58%), Gaps = 91/883 (10%)
Query: 107 SCKGRCFERTFG---NCRCDAACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSL 163
SCKGRCFE +CRCD C +CC D+ E C++ W C K RCGE R +
Sbjct: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117
Query: 164 CACSDDCKDKGDCCINYSSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAE 223
C CS+DC +GDCC NY VC+GE WV++ CE I +CPAGF PP ++FS+DGFRA
Sbjct: 118 CHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRAS 177
Query: 224 YLHTWGGLLPVISKLKKCGTYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPK 283
Y+ ++P I KL+ CGT++ MRPVYPTKTFPN Y++ TGLYPESHGI+ N MYDP
Sbjct: 178 YMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPV 237
Query: 284 MNASFSLKSKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGS 343
+A+F L+ +EKFN W+ G+P+W+TA QG+K+GTFFW +
Sbjct: 238 FDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SVV 279
Query: 344 VPFEERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSE--------------- 388
+P E RIL +LQWL LP ERP Y Y E+PD SGH YGP E
Sbjct: 280 IPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEESSYGSPFTPAKRPK 339
Query: 389 -------------------------------------VIKALQRVDGMVGMLMDGLKELN 411
+ L+ +D +VG LMDGLK+L
Sbjct: 340 RKVAPKRRQERPVAPPKKRRRKIHRMDHYAAETRQDKMTNPLREIDKIVGQLMDGLKQLK 399
Query: 412 LHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNY 471
LHRC+N+I + DHGME +C + +L+ YL +V +I ++ G R+R + Y +
Sbjct: 400 LHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKY--DP 457
Query: 472 EGIARNLSCREPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSE--RKY 529
+ I NL+C++P+QHFKPYLK LPKRLH+A + RIE + ++ +W +A P + +K
Sbjct: 458 KAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKP 517
Query: 530 CGSGF----HGSDNVFSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLLNLTPAPNN 585
G F HG DN ++MQ +FVGYG FK+ + FENIE+YN+MCDLL L PAPNN
Sbjct: 518 SGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNN 577
Query: 586 GTHGSLNHLLKNPVYTPKHPKEV-HPLVQCPFTRNPRDNLGCSCNPSILPIEDFQTQFNL 644
GTHGSLNHLL+ + P P+EV P +LGC+C+ + P ++ + N
Sbjct: 578 GTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEP-KNKLDELNK 636
Query: 645 TVAEEKIIKHETLPYGRPRVLQKENTICLLSQHQFMSGYSQDILMPLWTSYTVDRNDSFS 704
+ + + L YGRP VL + +L F SGYS+ LMPLWTSYTV + S
Sbjct: 637 RLHTKGSTEERHLLYGRPAVLYR-TRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVS 695
Query: 705 T--EDFSNCLYQDFRIPLSPVHKCSFYKNNTKVSYGFLSPPQLNKNSSGIYSEALLTTNI 762
+ + ++C+ D R+ S C YKN+ ++SYGFL PP L+ + Y +A L TN+
Sbjct: 696 SVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKY-DAFLVTNM 754
Query: 763 VPMYQSFQVIWRYFHDTLLRKYAEERNGVNVVSGPVFDFDYDGRCDSLENLRQKRRVIRN 822
VPMY +F+ +W YF L++KYA ERNGVNV+SGP+FD+DYDG D+ + ++Q +
Sbjct: 755 VPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQ---YVEG 811
Query: 823 QEILIPTHFFIVLTSCKDTSQTPLHCEN-LDTLAFILPHRTDNSESCVHGKHDSSWVEEL 881
I +PTH++ ++TSC D +Q C+ L +FILPHR DN ESC + +S WVEEL
Sbjct: 812 SSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEEL 871
Query: 882 LMLHRARITDVEHITGLSFYQQRKEPVSDILKLKTHLPTFSQE 924
+ +H AR+ D+EH+T L F+++ +IL LKT+L T+ E
Sbjct: 872 MKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESE 914
>gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4
(putative function) [Homo sapiens]
Length = 453
Score = 250 bits (638), Expect = 5e-66
Identities = 147/388 (37%), Positives = 201/388 (51%), Gaps = 19/388 (4%)
Query: 210 PPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTKNMRPVYPTKTFPNHYSIVTGLYP 269
P LL S DGFRA+YL + P + K G ++++ V+ TKTFPNHYSIVTGLY
Sbjct: 26 PKLLLVSFDGFRADYLKNYE--FPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYE 83
Query: 270 ESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAKYQ-GLKSGTFFWPGSDVE 328
ESHGI+ N MYD FS S +K W + PIWVT + Q S WPG+DV
Sbjct: 84 ESHGIVANSMYDAVTKKHFS-DSNDKDPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDVP 142
Query: 329 INGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSE 388
I+ + YN SV FEER+ + WL + F TLY EEPD+SGH YGP E
Sbjct: 143 IHDTISSYFMNYNSSVSFEERLNNITMWLN-NSNPPVTFATLYWEEPDASGHKYGPEDKE 201
Query: 389 -VIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNI 447
+ + L+++D ++G L+ LK L L LN+I+ SDHGM Q S + I L+ +
Sbjct: 202 NMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSYYT 261
Query: 448 KVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPKRLHFAKSDRI 507
+ P A + P + Y+ + + H YLK +P R ++ +DRI
Sbjct: 262 LIDLSPVAAILPKINRTEVYN----------KLKNCSPHMNVYLKEDIPNRFYYQHNDRI 311
Query: 508 EPLTFYLDPQWQLALNPSERKYCGSGFHGSDNVFSNMQALFVGYGPGFKHGIEADTFENI 567
+P+ D W + LN S +K G HG DN +M +GP F G + T +
Sbjct: 312 QPIILVADEGWTIVLNESSQKL---GDHGYDNSLPSMHPFLAAHGPAFHKGYKHSTINIV 368
Query: 568 EVYNLMCDLLNLTPAPNNGTHGSLNHLL 595
++Y +MC +L L P PNNGT G LL
Sbjct: 369 DIYPMMCHILGLKPHPNNGTFGHTKCLL 396
>gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5
(putative function) [Homo sapiens]
Length = 477
Score = 241 bits (614), Expect = 3e-63
Identities = 135/386 (34%), Positives = 208/386 (53%), Gaps = 16/386 (4%)
Query: 213 LLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTKNMRPVYPTKTFPNHYSIVTGLYPESH 272
LL S DGFR +YL+ P + K G + K + V+ TKT+PNHY++VTGL+ E+H
Sbjct: 31 LLVSFDGFRWDYLYKVP--TPHFHYIMKYGVHVKQVTNVFITKTYPNHYTLVTGLFAENH 88
Query: 273 GIIDNKMYDPKMNASFSLKSKEKFNPE-WYKGEPIWVTAKYQGLKSGTFFWPGSDVEING 331
GI+ N M+DP N SFSL ++ + W + PIW+T + G SG WPG+DV+I+
Sbjct: 89 GIVANDMFDPIRNKSFSLDHMNIYDSKFWEEATPIWITNQRAGHTSGAAMWPGTDVKIHK 148
Query: 332 IFPDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIK 391
FP Y YN SV FE+R+ +++W E + LY E+PD GH GP S +
Sbjct: 149 RFPTHYMPYNESVSFEDRVAKIIEW--FTSKEPINLGLLYWEDPDDMGHHLGPDSPLMGP 206
Query: 392 ALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIY 451
+ +D +G L+ LK+ L LNLI+ SDHGM Q S ++ I L++YL +
Sbjct: 207 VISDIDKKLGYLIQMLKKAKLWNTLNLIITSDHGMTQCSEERLIELDQYLDKDHYTLIDQ 266
Query: 452 GPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPKRLHFAKSDRIEPLT 511
P A + P + ++ + L+ PN Y K +P+R H+ + RI+P+
Sbjct: 267 SPVAAILPKE-------GKFDEVYEALTHAHPN--LTVYKKEDVPERWHYKYNSRIQPII 317
Query: 512 FYLDPQWQLALNPSERKYCGSGFHGSDNVFSNMQALFVGYGPGFKHGIEADTFENIEVYN 571
D W + N S+ G+ HG DN ++M +F+ +GP F+ + + ++Y
Sbjct: 318 AVADEGWHILQNKSDDFLLGN--HGYDNALADMHPIFLAHGPAFRKNFSKEAMNSTDLYP 375
Query: 572 LMCDLLNLTPAPNNGTHGSLNHLLKN 597
L+C LLN+T P+NG+ ++ LL +
Sbjct: 376 LLCHLLNITAMPHNGSFWNVQDLLNS 401
>gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6
[Homo sapiens]
Length = 440
Score = 199 bits (506), Expect = 1e-50
Identities = 135/406 (33%), Positives = 202/406 (49%), Gaps = 29/406 (7%)
Query: 213 LLFSLDGFRAEYLHTWG-GLLPVISKLKKCGTYTKNMRPVYPTKTFPNHYSIVTGLYPES 271
L+F LDGFR++Y+ LP ++ G + P +P+ ++PN+Y+++TG + E
Sbjct: 27 LVFLLDGFRSDYISDEALESLPGFKEIVSRGVKVDYLTPDFPSLSYPNYYTLMTGRHCEV 86
Query: 272 HGIIDNKMYDPKMNASFSLK-SKEKFNPEWYKG-EPIWVTAKYQGLKSGTFFWPGSDVEI 329
H +I N M+DP N SF + +K+ P W+ G EP+WVT K ++WPG +VEI
Sbjct: 87 HQMIGNYMWDPTTNKSFDIGVNKDSLMPLWWNGSEPLWVTLTKAKRKVYMYYWPGCEVEI 146
Query: 330 NGIFPDIYKMYNGSVPFEERIL-AVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSE 388
G+ P Y +VP + AV L K R +Y E D GH YGP S +
Sbjct: 147 LGVRPTYCLEYK-NVPTDINFANAVSDALDSFKSGRADLAAIYHERIDVEGHHYGPASPQ 205
Query: 389 VIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGS-CKKYIYLNKY--LGDVK 445
AL+ VD ++ + ++E L LN+I+ SDHGM K I LNKY L D++
Sbjct: 206 RKDALKAVDTVLKYMTKWIQERGLQDRLNVIIFSDHGMTDIFWMDKVIELNKYISLNDLQ 265
Query: 446 NIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPKRLHFAKSD 505
+K GP L P+ P K+ I LS E H Y K +P R ++ K
Sbjct: 266 QVKD-RGPVVSLWPA--PGKHSE-----IYNKLSTVE---HMTVYEKEAIPSRFYYKKGK 314
Query: 506 RIEPLTFYLDPQWQLALN----------PSERKYCGSGFHGSDNVFSNMQALFVGYGPGF 555
+ PLT D W + N R+ G+HG DN +M+ +F+ +GP F
Sbjct: 315 FVSPLTLVADEGWFITENREMLPFWMNSTGRREGWQRGWHGYDNELMDMRGIFLAFGPDF 374
Query: 556 KHGIEADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLLKNPVYT 601
K A +++VYN+MC+++ +TP PNNG+ + +LK T
Sbjct: 375 KSNFRAAPIRSVDVYNVMCNVVGITPLPNNGSWSRVMCMLKGRAST 420
>gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7
[Homo sapiens]
Length = 458
Score = 186 bits (471), Expect = 1e-46
Identities = 124/396 (31%), Positives = 185/396 (46%), Gaps = 29/396 (7%)
Query: 213 LLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTKNMRPVYPTKTFPNHYSIVTGLYPESH 272
LL S DGFR Y P + + + G + M P + T T P H+++VTG Y E+H
Sbjct: 34 LLVSFDGFRWNYDQDVD--TPNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIENH 91
Query: 273 GIIDNKMYDPKMNASFSLKSKEKFNPEWYKGE-PIWVTAKYQGLKSGTFFWPGSDVEING 331
G++ N Y+ + W G PIW+TA+ QGL++G+FF+PG +V G
Sbjct: 92 GVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQG 151
Query: 332 IF------PDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPV 385
+ I Y + I V+ W +E TLY EPDS+GH YGP
Sbjct: 152 VAVTRSRKEGIAHNYKNETEWRANIDTVMAWFT---EEDLDLVTLYFGEPDSTGHRYGPE 208
Query: 386 SSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSCKK------YIYLNK 439
S E + +++VD VG L + + +L LNLI+ SDHGM + + + N
Sbjct: 209 SPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFPNF 268
Query: 440 YLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPKRL 499
D++ + YGP L P + E + L P H Y K P+
Sbjct: 269 TFRDIEFELLDYGPNGMLLPKE-------GRLEKVYDALKDAHPKLHV--YKKEAFPEAF 319
Query: 500 HFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNVFSNMQALFVGYGPGFKHGI 559
H+A + R+ PL Y D + ++ +G HG DN +M+ +F GP F+ G+
Sbjct: 320 HYANNPRVTPLLMYSDLGY--VIHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRAGL 377
Query: 560 EADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLL 595
E + FE++ VY LMC LL + P N+G +L +L
Sbjct: 378 EVEPFESVHVYELMCRLLGIVPEANDGHLATLLPML 413
>gi|239755573 PREDICTED: similar to ectonucleotide
pyrophosphatase/phosphodiesterase 5 (putative function)
[Homo sapiens]
Length = 661
Score = 82.4 bits (202), Expect = 2e-15
Identities = 70/261 (26%), Positives = 111/261 (42%), Gaps = 41/261 (15%)
Query: 367 FYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGM 426
F TLY +PD+ GH + P + +Q++D + L+ G E + + +I+ DHGM
Sbjct: 281 FVTLYYRQPDNVGHRFKPEAENRKLMIQQLDRTIWYLV-GATEKHSLQSPQVIITXDHGM 339
Query: 427 ----EQGSCKKYIYLN--KYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSC 480
++ + K N K+ VK V YG P + E + + L
Sbjct: 340 MTVKKRPNVNKIXLSNYIKFRDWVKFDIVGYGGFGLPLPKLGQE-------EALYQALKN 392
Query: 481 REPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKY----------- 529
P+ H Y K P+ H AK DR+ P+ Y + ++ L+ S R +
Sbjct: 393 AHPHLHI--YKKEEFPEHFHLAKHDRVLPIVMYANSSYRY-LDSSMRTFNETRTFPTDQP 449
Query: 530 -------------CGSGFHGSDNVFSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDL 576
G HG DNV +M+ +F +GP FK A+TF +I +Y +C L
Sbjct: 450 DSLREQDARIIMCFNKGSHGFDNVLMDMKTIFRDFGPDFKKNGLAETFNSIHIYPFVCKL 509
Query: 577 LNLTPAPNNGTHGSLNHLLKN 597
L + P +NG+ +L N
Sbjct: 510 LGVXPQTHNGSLAVTQEMLVN 530
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 53.1 bits (126), Expect = 1e-06
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 6/97 (6%)
Query: 90 ILGCIFGLKPSCAKEVKSCKGRCFE--RTFGNCRCDAACVELGNCCLDYQETCIEPEHIW 147
+L +F ++ ++++ SC GRC E C CD C CC D++ C
Sbjct: 12 LLLSVFVIQQVSSQDLSSCAGRCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAE---L 68
Query: 148 TCNKFRCGEKRLTRSLCACSDDCKDKGDCCINYSSVC 184
+C K RC E C C CK CC +Y S C
Sbjct: 69 SC-KGRCFESFERGRECDCDAQCKKYDKCCPDYESFC 104
Score = 46.2 bits (108), Expect = 1e-04
Identities = 23/52 (44%), Positives = 26/52 (50%), Gaps = 3/52 (5%)
Query: 93 CIFGLKPSCAKEVKSCKGRCFE--RTFGNCRCDAACVELGNCCLDYQETCIE 142
C K C E+ SCKGRCFE C CDA C + CC DY+ C E
Sbjct: 56 CCPDFKRVCTAEL-SCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFCAE 106
Score = 32.7 bits (73), Expect = 1.6
Identities = 13/37 (35%), Positives = 19/37 (51%)
Query: 153 RCGEKRLTRSLCACSDDCKDKGDCCINYSSVCQGEKS 189
RCGE + C C +C+ +CC ++ VC E S
Sbjct: 33 RCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAELS 69
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 53.1 bits (126), Expect = 1e-06
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 6/97 (6%)
Query: 90 ILGCIFGLKPSCAKEVKSCKGRCFE--RTFGNCRCDAACVELGNCCLDYQETCIEPEHIW 147
+L +F ++ ++++ SC GRC E C CD C CC D++ C
Sbjct: 12 LLLSVFVIQQVSSQDLSSCAGRCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAE---L 68
Query: 148 TCNKFRCGEKRLTRSLCACSDDCKDKGDCCINYSSVC 184
+C K RC E C C CK CC +Y S C
Sbjct: 69 SC-KGRCFESFERGRECDCDAQCKKYDKCCPDYESFC 104
Score = 46.2 bits (108), Expect = 1e-04
Identities = 23/52 (44%), Positives = 26/52 (50%), Gaps = 3/52 (5%)
Query: 93 CIFGLKPSCAKEVKSCKGRCFE--RTFGNCRCDAACVELGNCCLDYQETCIE 142
C K C E+ SCKGRCFE C CDA C + CC DY+ C E
Sbjct: 56 CCPDFKRVCTAEL-SCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFCAE 106
Score = 32.7 bits (73), Expect = 1.6
Identities = 13/37 (35%), Positives = 19/37 (51%)
Query: 153 RCGEKRLTRSLCACSDDCKDKGDCCINYSSVCQGEKS 189
RCGE + C C +C+ +CC ++ VC E S
Sbjct: 33 RCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAELS 69
>gi|209969800 RPE-spondin [Homo sapiens]
Length = 264
Score = 47.4 bits (111), Expect = 6e-05
Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 12/71 (16%)
Query: 79 SLVLSVCVLTTILGCIFGLKPSCAKEVKSCKGR---CF------ERTFGNCRCDAACVEL 129
+L +++C L+ + G + CA+ + C GR CF +R +G C CD AC
Sbjct: 3 TLWMALCALSRLWP---GAQAGCAEAGRCCPGRDPACFARGWRLDRVYGTCFCDQACRFT 59
Query: 130 GNCCLDYQETC 140
G+CC DY C
Sbjct: 60 GDCCFDYDRAC 70
Score = 38.1 bits (87), Expect = 0.038
Identities = 19/70 (27%), Positives = 24/70 (34%), Gaps = 10/70 (14%)
Query: 124 AACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSLCACSDDCKDKGDCCINYSSV 183
A C E G CC C W ++ C C C+ GDCC +Y
Sbjct: 20 AGCAEAGRCCPGRDPACFARG--WRLDR--------VYGTCFCDQACRFTGDCCFDYDRA 69
Query: 184 CQGEKSWVEE 193
C +V E
Sbjct: 70 CPARPCFVGE 79
>gi|5174623 placental protein 11 precursor [Homo sapiens]
Length = 369
Score = 46.2 bits (108), Expect = 1e-04
Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 107 SCKGRCFER--TFGNCRCDAACVELGNCCLDYQETCIEPE 144
SC+GRC+E C C+A C E GNCC D++ C + E
Sbjct: 48 SCQGRCYEAFDKHHQCHCNARCQEFGNCCKDFESLCSDHE 87
Score = 30.4 bits (67), Expect = 7.9
Identities = 15/54 (27%), Positives = 27/54 (50%), Gaps = 6/54 (11%)
Query: 153 RCGEKRLTRSLCACSDDCKDKGDCCINYSSVCQGEK------SWVEEPCESINE 200
RC E C C+ C++ G+CC ++ S+C + + +E +SI+E
Sbjct: 52 RCYEAFDKHHQCHCNARCQEFGNCCKDFESLCSDHEVSHSSDAITKEEIQSISE 105
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 44.7 bits (104), Expect = 4e-04
Identities = 22/55 (40%), Positives = 31/55 (56%), Gaps = 3/55 (5%)
Query: 90 ILGCIFGLKPSCAKEVKSCKGRCFE--RTFGNCRCDAACVELGNCCLDYQETCIE 142
+L +F ++ ++E+ SCKGRCFE C CDA C + CC DY+ C E
Sbjct: 12 LLLSVFVIQQVSSQEL-SCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFCAE 65
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 44.7 bits (104), Expect = 4e-04
Identities = 22/55 (40%), Positives = 31/55 (56%), Gaps = 3/55 (5%)
Query: 90 ILGCIFGLKPSCAKEVKSCKGRCFE--RTFGNCRCDAACVELGNCCLDYQETCIE 142
+L +F ++ ++E+ SCKGRCFE C CDA C + CC DY+ C E
Sbjct: 12 LLLSVFVIQQVSSQEL-SCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFCAE 65
>gi|169217659 PREDICTED: similar to ectonucleotide
pyrophosphatase/phosphodiesterase 5 [Homo sapiens]
Length = 542
Score = 41.2 bits (95), Expect = 0.005
Identities = 47/185 (25%), Positives = 72/185 (38%), Gaps = 36/185 (19%)
Query: 348 ERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGL 407
E I ++ W E F TL EPD+ GH +GP + +Q++
Sbjct: 44 ENIDTIMNWFT---KEDFDFVTLCYREPDNVGHRFGPEAENRKLMIQQIG---------- 90
Query: 408 KELNLHRCLNLILISDHGM----EQGSCKKYIYLN--KYLGDVKNIKVIYGPAARLRPSD 461
R + +I+ DHG+ ++ + K N K+ VK V YG P
Sbjct: 91 ------RTIGVIITRDHGVTTEKKRPNVNKIPLSNYIKFRDWVKFDIVGYGGFGMPLPK- 143
Query: 462 VPDKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQL- 520
S E + + L P+ H Y K P+ H AK DR+ P+ Y + + +
Sbjct: 144 ------SGQEEALYQALKNAYPHLHI--YKKEEFPEHFHIAKHDRVLPIVMYANSGYTIN 195
Query: 521 -ALNP 524
A NP
Sbjct: 196 GAENP 200
>gi|169167316 PREDICTED: similar to ectonucleotide
pyrophosphatase/phosphodiesterase 5 [Homo sapiens]
Length = 542
Score = 41.2 bits (95), Expect = 0.005
Identities = 47/185 (25%), Positives = 72/185 (38%), Gaps = 36/185 (19%)
Query: 348 ERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGL 407
E I ++ W E F TL EPD+ GH +GP + +Q++
Sbjct: 44 ENIDTIMNWFT---KEDFDFVTLCYREPDNVGHRFGPEAENRKLMIQQIG---------- 90
Query: 408 KELNLHRCLNLILISDHGM----EQGSCKKYIYLN--KYLGDVKNIKVIYGPAARLRPSD 461
R + +I+ DHG+ ++ + K N K+ VK V YG P
Sbjct: 91 ------RTIGVIITRDHGVTTEKKRPNVNKIPLSNYIKFRDWVKFDIVGYGGFGMPLPK- 143
Query: 462 VPDKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQL- 520
S E + + L P+ H Y K P+ H AK DR+ P+ Y + + +
Sbjct: 144 ------SGQEEALYQALKNAYPHLHI--YKKEEFPEHFHIAKHDRVLPIVMYANSGYTIN 195
Query: 521 -ALNP 524
A NP
Sbjct: 196 GAENP 200
>gi|10092665 sushi domain containing 2 [Homo sapiens]
Length = 822
Score = 38.9 bits (89), Expect = 0.022
Identities = 23/60 (38%), Positives = 32/60 (53%), Gaps = 4/60 (6%)
Query: 83 SVCVLTTILGCIFGLKPSCAKEVKSCKGRCFERTFGNCRCDAACVELGNCCLDYQETCIE 142
++ +L T LG G P+ A +SC RC G C C C LG CCLD+++ C+E
Sbjct: 9 ALLLLATALGP--GPGPT-ADAQESCSMRCGALD-GPCSCHPTCSGLGTCCLDFRDFCLE 64
>gi|224451073 endo/exonuclease (5'-3'), endonuclease G-like isoform
1 precursor [Homo sapiens]
Length = 368
Score = 38.5 bits (88), Expect = 0.029
Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 29/223 (13%)
Query: 683 YSQDILMPLWTSYTVDRNDSFSTEDFSNCLYQDFRIPLSPVHKCSFYKN--NTKVSYGFL 740
Y Q +P W + ++ D +C ++ P P +F ++ + S G +
Sbjct: 84 YDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPD--PNIPPTFSAFNEDYVGSGWSRGHM 141
Query: 741 SPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFH--DTLLRKYAEERNGVNVVSGPV 798
+P NK SS +E +NIVP Q F Y++ + R+ E V VVSGP+
Sbjct: 142 APAGNNKFSSKAMAETFYLSNIVP--QDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPL 199
Query: 799 FDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKDTSQTPLHCENLDTLAFIL 858
G + + +VI + +P+H + V+ + + + T E L AF++
Sbjct: 200 TLPQTRGDGKKIVSY----QVIGEDNVAVPSHLYKVILARRSSVST----EPLALGAFVV 251
Query: 859 PHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSFY 901
P +++ + L + + D+E ++GL F+
Sbjct: 252 P-------------NEAIGFQPQLTEFQVSLQDLEKLSGLVFF 281
>gi|239749375 PREDICTED: hypothetical protein XP_002347018 [Homo
sapiens]
Length = 265
Score = 38.5 bits (88), Expect = 0.029
Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 3/41 (7%)
Query: 8 GGGSRGGEGGRAPREGPAGNGRDRGRSHAAEAPGDPQAAAS 48
GGG++G GGR P PAG G D G + PG AAA+
Sbjct: 109 GGGAKGQRGGRGPPNPPAGQGSDTG---GTKTPGTTTAAAA 146
>gi|239743512 PREDICTED: hypothetical protein XP_002342879 [Homo
sapiens]
Length = 265
Score = 38.5 bits (88), Expect = 0.029
Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 3/41 (7%)
Query: 8 GGGSRGGEGGRAPREGPAGNGRDRGRSHAAEAPGDPQAAAS 48
GGG++G GGR P PAG G D G + PG AAA+
Sbjct: 109 GGGAKGQRGGRGPPNPPAGQGSDTG---GTKTPGTTTAAAA 146
>gi|88853069 vitronectin precursor [Homo sapiens]
Length = 478
Score = 37.7 bits (86), Expect = 0.050
Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 2/37 (5%)
Query: 106 KSCKGRCFE--RTFGNCRCDAACVELGNCCLDYQETC 140
+SCKGRC E C+CD C +CC DY C
Sbjct: 22 ESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAEC 58
>gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]
Length = 476
Score = 37.7 bits (86), Expect = 0.050
Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 10/52 (19%)
Query: 149 CNKFRCGEKR---------LTRSLCACSDDC-KDKGDCCINYSSVCQGEKSW 190
C F C E R +LC C C ++ DCC +Y S C+ EK W
Sbjct: 57 CRNFGCCEDRDDGCVTEFYAANALCYCDKFCDRENSDCCPDYKSFCREEKEW 108
>gi|239756937 PREDICTED: hypothetical protein [Homo sapiens]
Length = 294
Score = 36.6 bits (83), Expect = 0.11
Identities = 25/55 (45%), Positives = 26/55 (47%), Gaps = 9/55 (16%)
Query: 3 RDGCA--GGGSRGGE---GGRAPREGPAGNGRDRGRSHAAEAPGDPQAAASLLAP 52
R GC G GSRG E G R P GP R RGRS APG Q A+ P
Sbjct: 77 RAGCGAHGPGSRGRERRRGSRDPPAGPVARARARGRS----APGSAQPASGAAGP 127
>gi|239751449 PREDICTED: hypothetical protein XP_002347867 [Homo
sapiens]
Length = 315
Score = 36.6 bits (83), Expect = 0.11
Identities = 25/55 (45%), Positives = 26/55 (47%), Gaps = 9/55 (16%)
Query: 3 RDGCA--GGGSRGGE---GGRAPREGPAGNGRDRGRSHAAEAPGDPQAAASLLAP 52
R GC G GSRG E G R P GP R RGRS APG Q A+ P
Sbjct: 77 RAGCGAHGPGSRGRERRRGSRDPPAGPVARARARGRS----APGSAQPASGAAGP 127
>gi|239745954 PREDICTED: hypothetical protein XP_002343623 [Homo
sapiens]
Length = 315
Score = 36.6 bits (83), Expect = 0.11
Identities = 25/55 (45%), Positives = 26/55 (47%), Gaps = 9/55 (16%)
Query: 3 RDGCA--GGGSRGGE---GGRAPREGPAGNGRDRGRSHAAEAPGDPQAAASLLAP 52
R GC G GSRG E G R P GP R RGRS APG Q A+ P
Sbjct: 77 RAGCGAHGPGSRGRERRRGSRDPPAGPVARARARGRS----APGSAQPASGAAGP 127
>gi|224451075 endo/exonuclease (5'-3'), endonuclease G-like isoform
2 precursor [Homo sapiens]
Length = 318
Score = 36.2 bits (82), Expect = 0.14
Identities = 41/168 (24%), Positives = 73/168 (43%), Gaps = 25/168 (14%)
Query: 736 SYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFH--DTLLRKYAEERNGVNV 793
S G ++P NK SS +E +NIVP Q F Y++ + R+ E V V
Sbjct: 87 SRGHMAPAGNNKFSSKAMAETFYLSNIVP--QDFDNNSGYWNRIEMYCRELTERFEDVWV 144
Query: 794 VSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKDTSQTPLHCENLDT 853
VSGP+ G + + +VI + +P+H + V+ + + + T E L
Sbjct: 145 VSGPLTLPQTRGDGKKIVSY----QVIGEDNVAVPSHLYKVILARRSSVST----EPLAL 196
Query: 854 LAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSFY 901
AF++P +++ + L + + D+E ++GL F+
Sbjct: 197 GAFVVP-------------NEAIGFQPQLTEFQVSLQDLEKLSGLVFF 231
>gi|194363768 homeobox D9 [Homo sapiens]
Length = 352
Score = 36.2 bits (82), Expect = 0.14
Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 4/71 (5%)
Query: 5 GCAGGGSRGGEG--GRAPREGPAG--NGRDRGRSHAAEAPGDPQAAASLLAPMDVGEEPL 60
G AGGG GG G GR P GP+G NGR G A P AAS +
Sbjct: 128 GGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSS 187
Query: 61 EKAARARTAKD 71
K A++
Sbjct: 188 SKRTECSVARE 198
>gi|239743493 PREDICTED: hypothetical protein XP_002342862 [Homo
sapiens]
Length = 169
Score = 36.2 bits (82), Expect = 0.14
Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 3/66 (4%)
Query: 347 EERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDG 406
+E I V+ W E F TL EPD+ GH +GP + + +Q++D +G L+
Sbjct: 94 KENIDTVMNWFT---KEDFDFVTLCYREPDNVGHRFGPEAEKRKLMIQQIDRTIGYLVGA 150
Query: 407 LKELNL 412
++ +L
Sbjct: 151 TEKHSL 156
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,664,607
Number of Sequences: 37866
Number of extensions: 2080145
Number of successful extensions: 7809
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 63
Number of HSP's that attempted gapping in prelim test: 7459
Number of HSP's gapped (non-prelim): 310
length of query: 925
length of database: 18,247,518
effective HSP length: 112
effective length of query: 813
effective length of database: 14,006,526
effective search space: 11387305638
effective search space used: 11387305638
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.