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Search of human proteins with 170016077
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|170016077 ATPase type 13A1 [Homo sapiens]
(1204 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|170016077 ATPase type 13A1 [Homo sapiens] 2394 0.0
gi|148839292 ATPase type 13A3 [Homo sapiens] 286 1e-76
gi|66932949 ATPase type 13A4 [Homo sapiens] 275 1e-73
gi|66730421 ATPase type 13A5 [Homo sapiens] 267 5e-71
gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens] 261 4e-69
gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens] 261 4e-69
gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens] 254 3e-67
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 108 2e-23
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] 104 6e-22
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 103 1e-21
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] 103 1e-21
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 103 1e-21
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] 103 1e-21
gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] 100 1e-20
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 97 9e-20
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 90 1e-17
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 90 1e-17
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 90 1e-17
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 90 1e-17
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 86 2e-16
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 86 2e-16
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 84 1e-15
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 82 3e-15
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 82 3e-15
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 82 4e-15
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 81 5e-15
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 81 5e-15
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 81 5e-15
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 81 5e-15
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 81 5e-15
>gi|170016077 ATPase type 13A1 [Homo sapiens]
Length = 1204
Score = 2394 bits (6203), Expect = 0.0
Identities = 1204/1204 (100%), Positives = 1204/1204 (100%)
Query: 1 MAAAAAVGNAVPCGARPCGVRPDGQPKPGPQPRALLAAGPALIANGDELVAAVWPYRRLA 60
MAAAAAVGNAVPCGARPCGVRPDGQPKPGPQPRALLAAGPALIANGDELVAAVWPYRRLA
Sbjct: 1 MAAAAAVGNAVPCGARPCGVRPDGQPKPGPQPRALLAAGPALIANGDELVAAVWPYRRLA 60
Query: 61 LLRRLTVLPFAGLLYPAWLGAAAAGCWGWGSSWVQIPEAALLVLATICLAHALTVLSGHW 120
LLRRLTVLPFAGLLYPAWLGAAAAGCWGWGSSWVQIPEAALLVLATICLAHALTVLSGHW
Sbjct: 61 LLRRLTVLPFAGLLYPAWLGAAAAGCWGWGSSWVQIPEAALLVLATICLAHALTVLSGHW 120
Query: 121 SVHAHCALTCTPEYDPSKATFVKVVPTPNNGSTELVALHRNEGEDGLEVLSFEFQKIKYS 180
SVHAHCALTCTPEYDPSKATFVKVVPTPNNGSTELVALHRNEGEDGLEVLSFEFQKIKYS
Sbjct: 121 SVHAHCALTCTPEYDPSKATFVKVVPTPNNGSTELVALHRNEGEDGLEVLSFEFQKIKYS 180
Query: 181 YDALEKKQFLPVAFPVGNAFSYYQSNRGFQEDSEIRAAEKKFGSNKAEMVVPDFSELFKE 240
YDALEKKQFLPVAFPVGNAFSYYQSNRGFQEDSEIRAAEKKFGSNKAEMVVPDFSELFKE
Sbjct: 181 YDALEKKQFLPVAFPVGNAFSYYQSNRGFQEDSEIRAAEKKFGSNKAEMVVPDFSELFKE 240
Query: 241 RATAPFFVFQVFCVGLWCLDEYWYYSVFTLSMLVAFEASLVQQQMRNMSEIRKMGNKPHM 300
RATAPFFVFQVFCVGLWCLDEYWYYSVFTLSMLVAFEASLVQQQMRNMSEIRKMGNKPHM
Sbjct: 241 RATAPFFVFQVFCVGLWCLDEYWYYSVFTLSMLVAFEASLVQQQMRNMSEIRKMGNKPHM 300
Query: 301 IQVYRSRKWRPIASDEIVPGDIVSIGRSPQENLVPCDVLLLRGRCIVDEAMLTGESVPQM 360
IQVYRSRKWRPIASDEIVPGDIVSIGRSPQENLVPCDVLLLRGRCIVDEAMLTGESVPQM
Sbjct: 301 IQVYRSRKWRPIASDEIVPGDIVSIGRSPQENLVPCDVLLLRGRCIVDEAMLTGESVPQM 360
Query: 361 KEPIEDLSPDRVLDLQADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFN 420
KEPIEDLSPDRVLDLQADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFN
Sbjct: 361 KEPIEDLSPDRVLDLQADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFN 420
Query: 421 TSQGKLLRTILFGVKRVTANNLETFIFILFLLVFAIAAAAYVWIEGTKDPSRNRYKLFLE 480
TSQGKLLRTILFGVKRVTANNLETFIFILFLLVFAIAAAAYVWIEGTKDPSRNRYKLFLE
Sbjct: 421 TSQGKLLRTILFGVKRVTANNLETFIFILFLLVFAIAAAAYVWIEGTKDPSRNRYKLFLE 480
Query: 481 CTLILTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTS 540
CTLILTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTS
Sbjct: 481 CTLILTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTS 540
Query: 541 DSLVVRGVAGLRDGKEVTPVSSIPVETHRALASCHSLMQLDDGTLVGDPLEKAMLTAVDW 600
DSLVVRGVAGLRDGKEVTPVSSIPVETHRALASCHSLMQLDDGTLVGDPLEKAMLTAVDW
Sbjct: 541 DSLVVRGVAGLRDGKEVTPVSSIPVETHRALASCHSLMQLDDGTLVGDPLEKAMLTAVDW 600
Query: 601 TLTKDEKVFPRSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPETL 660
TLTKDEKVFPRSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPETL
Sbjct: 601 TLTKDEKVFPRSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPETL 660
Query: 661 HSMFSQCPPDYHHIHTEISREGARVLALGYKELGHLTHQQAREVKREALECSLKFVGFIV 720
HSMFSQCPPDYHHIHTEISREGARVLALGYKELGHLTHQQAREVKREALECSLKFVGFIV
Sbjct: 661 HSMFSQCPPDYHHIHTEISREGARVLALGYKELGHLTHQQAREVKREALECSLKFVGFIV 720
Query: 721 VSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLILQPPSEKGR 780
VSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLILQPPSEKGR
Sbjct: 721 VSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLILQPPSEKGR 780
Query: 781 QCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQATDPQQLLRLIPHVQVFARV 840
QCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQATDPQQLLRLIPHVQVFARV
Sbjct: 781 QCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQATDPQQLLRLIPHVQVFARV 840
Query: 841 APKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVALLANAPERVVERRRRPRDSP 900
APKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVALLANAPERVVERRRRPRDSP
Sbjct: 841 APKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVALLANAPERVVERRRRPRDSP 900
Query: 901 TLSNSGIRATSRTAKQRSGLPPSEEQPTSQRDRLSQVLRDLEDESTPIVKLGDASIAAPF 960
TLSNSGIRATSRTAKQRSGLPPSEEQPTSQRDRLSQVLRDLEDESTPIVKLGDASIAAPF
Sbjct: 901 TLSNSGIRATSRTAKQRSGLPPSEEQPTSQRDRLSQVLRDLEDESTPIVKLGDASIAAPF 960
Query: 961 TSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKFSDFQATLQ 1020
TSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKFSDFQATLQ
Sbjct: 961 TSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKFSDFQATLQ 1020
Query: 1021 GLLLAGCFLFISRSKPLKTLSRERPLPNIFNLYTILTVMLQFFVHFLSLVYLYREAQARS 1080
GLLLAGCFLFISRSKPLKTLSRERPLPNIFNLYTILTVMLQFFVHFLSLVYLYREAQARS
Sbjct: 1021 GLLLAGCFLFISRSKPLKTLSRERPLPNIFNLYTILTVMLQFFVHFLSLVYLYREAQARS 1080
Query: 1081 PEKQEQFVDLYKEFEPSLVNSTVYIMAMAMQMATFAINYKGPPFMESLPENKPLVWSLAV 1140
PEKQEQFVDLYKEFEPSLVNSTVYIMAMAMQMATFAINYKGPPFMESLPENKPLVWSLAV
Sbjct: 1081 PEKQEQFVDLYKEFEPSLVNSTVYIMAMAMQMATFAINYKGPPFMESLPENKPLVWSLAV 1140
Query: 1141 SLLAIIGLLLGSSPDFNSQFGLVDIPVEFKLVIAQVLLLDFCLALLADRVLQFFLGTPKL 1200
SLLAIIGLLLGSSPDFNSQFGLVDIPVEFKLVIAQVLLLDFCLALLADRVLQFFLGTPKL
Sbjct: 1141 SLLAIIGLLLGSSPDFNSQFGLVDIPVEFKLVIAQVLLLDFCLALLADRVLQFFLGTPKL 1200
Query: 1201 KVPS 1204
KVPS
Sbjct: 1201 KVPS 1204
>gi|148839292 ATPase type 13A3 [Homo sapiens]
Length = 1226
Score = 286 bits (731), Expect = 1e-76
Identities = 222/732 (30%), Positives = 365/732 (49%), Gaps = 94/732 (12%)
Query: 222 FGSNKAEMVVPDFSELFKERATAPFFVFQVFCVGLWCLDEYWYYSVFTLSMLVAFEASLV 281
+G N+ + VP +L + PF++FQ+F V LW DEY+YY++ + M + S +
Sbjct: 191 YGVNEIAVKVPSVFKLLIKEVLNPFYIFQLFSVILWSTDEYYYYALAIVVMSIVSIVSSL 250
Query: 282 QQQMRNMSEIRKMGNKPHMIQVYRSR---KWRPIASDEIVPGDIVSIGRSPQENLVPCDV 338
+ + M ++V R + I S ++VPGD++ I + ++PCD
Sbjct: 251 YSIRKQYVMLHDMVATHSTVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLNG--TIMPCDA 308
Query: 339 LLLRGRCIVDEAMLTGESVPQMKEPIEDLSPD------RVLDLQADSRLHVIFGGTKVVQ 392
+L+ G CIV+E+MLTGESVP K + + S D + + + R H +F GT V+Q
Sbjct: 309 VLINGTCIVNESMLTGESVPVTKTNLPNPSVDVKGIGDELYNPETHKR-HTLFCGTTVIQ 367
Query: 393 HIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLRTILFGVKRVTANNLETFIFILFLL 452
+ TG A V+RTGF+TS+G+L+R+IL+ + ++F+L L+
Sbjct: 368 ----TRFYTG-----ELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLV 418
Query: 453 VFAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLY 512
A Y I + + + +E I+T VPP LP ++ + + L K+
Sbjct: 419 AVAGIGFIYTIINSILNEVQVGV-IIIESLDIITITVPPALPAAMTAGIVYAQRRLKKIG 477
Query: 513 MYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVAGLRDGKEVTPVSSIPVET----- 567
++C P RI G++ + CFDKTGTLT D L + G+ + + + ++P ++ E
Sbjct: 478 IFCISPQRINICGQLNLVCFDKTGTLTEDGLDLWGIQRVENARFLSPEENVCNEMLVKSQ 537
Query: 568 -HRALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTL---TKDE-----KVFPRSIK---- 614
+A+CHSL ++ +G L GDPL+ M A+ W L T++E ++ P ++
Sbjct: 538 FVACMATCHSLTKI-EGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQ 596
Query: 615 --------------------TQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVK 654
T + I ++F F+SAL+RMSV+A LG D A +K
Sbjct: 597 LLPESTPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVA--RVLG--DRKMDAYMK 652
Query: 655 GAPETLHSMF--SQCPPDYHHIHTEISREGARVLALGYKEL-GHLTHQQAREVKREALEC 711
GAPE + + P D+ ++ + +++G RV+AL +++L LT + + + R+A+E
Sbjct: 653 GAPEAIAGLCKPETVPVDFQNVLEDFTKQGFRVIALAHRKLESKLTWHKVQNISRDAIEN 712
Query: 712 SLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLI 771
++ F+G I++ LK ++ AV+ ++ A+ R VM+TGD+ LTA VA++ I +I
Sbjct: 713 NMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVI 772
Query: 772 ----LQPPSEKGRQCEWRSIDG-------------SIVLPLARGSPKALAL-EYALCLTG 813
L P K + W D +I + L S + L + Y + G
Sbjct: 773 IAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNG 832
Query: 814 DG----LAHLQATDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDV 869
L H Q P+ +L H VFAR+AP QK +I +L+ + Y MCGDG ND
Sbjct: 833 KSFSVILEHFQDLVPKLML----HGTVFARMAPDQKTQLIEALQNVDYFVGMCGDGANDC 888
Query: 870 GALKHADVGVAL 881
GALK A G++L
Sbjct: 889 GALKRAHGGISL 900
Score = 71.2 bits (173), Expect = 5e-12
Identities = 59/258 (22%), Positives = 119/258 (46%), Gaps = 22/258 (8%)
Query: 953 DASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKF 1012
+AS+A+PFTSK SI C+ ++I++GR L+T+ +FK +AL ++I +S ++LY
Sbjct: 904 EASVASPFTSKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYSILSNL 963
Query: 1013 SDFQATLQGLLLAGCFLFISRSKPL-KTLSRERPLPNIFNLYTILTVMLQFF--VHFLSL 1069
DFQ L + +F P K L +RP + + + +V+ Q + F SL
Sbjct: 964 GDFQFLFIDLAIILVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIIICIGFQSL 1023
Query: 1070 VYLYREAQ---------------ARSPEKQEQFVDLYKEFEPSLV----NSTVYIMAMAM 1110
+ + + Q S VD E + + N+TV+ ++
Sbjct: 1024 GFFWVKQQPWYEVWHPKSDACNTTGSGFWNSSHVDNETELDEHNIQNYENTTVFFISSFQ 1083
Query: 1111 QMATFAINYKGPPFMESLPENKPLVWSLAVSLLAIIGLLLGSSPDFNSQFGLVDIPVEFK 1170
+ KG PF + +N V+S+ + I+ ++L + +V +P +++
Sbjct: 1084 YLIVAIAFSKGKPFRQPCYKNYFFVFSVIFLYIFILFIMLYPVASVDQVLQIVCVPYQWR 1143
Query: 1171 LVIAQVLLLDFCLALLAD 1188
+ + ++L++ +++ +
Sbjct: 1144 VTMLIIVLVNAFVSITVE 1161
>gi|66932949 ATPase type 13A4 [Homo sapiens]
Length = 1196
Score = 275 bits (704), Expect = 1e-73
Identities = 232/768 (30%), Positives = 371/768 (48%), Gaps = 81/768 (10%)
Query: 167 LEVLSFEFQKIKYSYDALEKKQFLPVAFP---VGNAFSYYQSNRGF-QEDSEIRAAEKKF 222
L+V + QKI+Y ++ LE QF + + +A + + G +E+ EIR
Sbjct: 126 LKVRCIKVQKIRYVWNYLEG-QFQKIGSLEDWLSSAKIHQKFGSGLTREEQEIRRLI--C 182
Query: 223 GSNKAEMVVPDFSELFKERATAPFFVFQVFCVGLWCLDEYWYYSVFTLSMLVAFEASLVQ 282
G N ++ V +L + PF++FQ+F V LW ++Y Y+ F + ++ SL
Sbjct: 183 GPNTIDVEVTPIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYA-FAIIIMSIISISLTV 241
Query: 283 QQMRNMS-EIRKMGNKPHMIQVY---RSRKWRPIASDEIVPGDIVSIGRSPQENLVPCDV 338
+R S ++ + + I V R + + S +VPGD++ + + + L+PCD
Sbjct: 242 YDLREQSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLLIL--TGNKVLMPCDA 299
Query: 339 LLLRGRCIVDEAMLTGESVPQMKEPIE--DLSPDRVLDLQADSRLHVIFGGTKVVQHIPP 396
+L+ G C+VDE MLTGES+P K P+ D S +AD + HV+F GT+V+Q
Sbjct: 300 VLIEGSCVVDEGMLTGESIPVTKTPLPKMDSSVPWKTQSEADYKRHVLFCGTEVIQ---- 355
Query: 397 QKATTGLKPVDSGCV-AYVLRTGFNTSQGKLLRTILFGVKRVTANNLETFIFILFLLVFA 455
K SG V A VL+TGFNT++G L+R+IL+ + F+L L+ A
Sbjct: 356 ------AKAACSGTVRAVVLQTGFNTAKGDLVRSILYPKPVNFQLYRDAIRFLLCLVGTA 409
Query: 456 IAAAAY---VWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLY 512
Y V++ + P ++ + ++T VPP LP L+ + + L K
Sbjct: 410 TIGMIYTLCVYVLSGEPPE----EVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKRG 465
Query: 513 MYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVA-----GLRDGKEVTPVSSIPV-E 566
++C P RI G++ + CFDKTGTLT D L + GV G ++ ++P
Sbjct: 466 IFCISPQRINVCGQLNLVCFDKTGTLTRDGLDLWGVVSCDRNGFQEVHSFASGQALPWGP 525
Query: 567 THRALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTLTKDEKVF----------------- 609
A+ASCHSL+ LD GT+ GDPL+ M A W + F
Sbjct: 526 LCAAMASCHSLILLD-GTIQGDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMVVKPCRT 584
Query: 610 PRSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPETLHSMFSQ--C 667
+ +G+ I +F F+SAL+RM+V+ +++G L ++ KGAPE + S
Sbjct: 585 ASQVPVEGIAILHQFPFSSALQRMTVIV--QEMGGDRLAFM---KGAPERVASFCQPETV 639
Query: 668 PPDYHHIHTEISREGARVLALGYKELGHLTHQQAREVKREALECSLKFVGFIVVSCPLKA 727
P + + +G RV+AL YK+L + H A + RE +E L F+G +++ LK
Sbjct: 640 PTSFVSELQIYTTQGFRVIALAYKKLENDHH--ATTLTRETVESDLIFLGLLILENRLKE 697
Query: 728 DSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLILQPPSE----KGRQCE 783
++K V+ E+ +A R VMITGDN TA VA++ + ++ +IL +E
Sbjct: 698 ETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASIS 757
Query: 784 WRSIDGSIVLPLARG----------SPKALALEYALCLTGDGLAHLQATDPQQLLRLIPH 833
W ++ + S K Y LTG + L +++ +
Sbjct: 758 WTLVEEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPKILIN 817
Query: 834 VQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
+FAR++P QK ++ ++L Y MCGDG ND GALK A VG++L
Sbjct: 818 GTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISL 865
Score = 83.6 bits (205), Expect = 1e-15
Identities = 70/268 (26%), Positives = 120/268 (44%), Gaps = 36/268 (13%)
Query: 953 DASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKF 1012
+AS+A+PFTSK +I+C+ H+IK+GR LVT+ MFK +AL ++I +LY E
Sbjct: 869 EASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLLLYWETNSL 928
Query: 1013 SDFQATLQGL---LLAGCFLFISRSKPLKTLSRERPLPNIFN----LYTILTVMLQFFVH 1065
S++Q Q L L G + ++ + P L RP + + L I ++L +H
Sbjct: 929 SNYQFLFQDLAITTLIGVTMNLNGAYP--KLVPFRPAGRLISPPLLLSVIFNILLSLAMH 986
Query: 1066 FLSLVYLYRE----------------------AQARSPEKQEQFVDLYKEFEPSLVNSTV 1103
+ + R+ +PEK E + FE N+TV
Sbjct: 987 IAGFILVQRQPWYSVEIHSACTVQNESISELTMSPTAPEKMES-NSTFTSFE----NTTV 1041
Query: 1104 YIMAMAMQMATFAINYKGPPFMESLPENKPLVWSLAVSLLAIIGLLLGSSPDFNSQFGLV 1163
+ + + + KG PF + N V L + L + +L P+ + L+
Sbjct: 1042 WFLGTINCITVALVFSKGKPFRQPTYTNYIFVLVLIIQLGVCLFILFADIPELYRRLDLL 1101
Query: 1164 DIPVEFKLVIAQVLLLDFCLALLADRVL 1191
PV ++ I +L L+F ++L+A+ +
Sbjct: 1102 CTPVLWRASIVIMLSLNFIVSLVAEEAV 1129
>gi|66730421 ATPase type 13A5 [Homo sapiens]
Length = 1218
Score = 267 bits (682), Expect = 5e-71
Identities = 229/770 (29%), Positives = 363/770 (47%), Gaps = 84/770 (10%)
Query: 167 LEVLSFEFQKIKYSYDALEKKQFLPVAFPVGNAFSYYQSNRGFQEDSEIRAAEKKF-GSN 225
L++ E QKI+Y ++ LEK+ N+ S G SE + + G N
Sbjct: 127 LKLRCMEVQKIRYVWNDLEKRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPN 186
Query: 226 KAEMVVPDFSELFKERATAPFFVFQVFCVGLWCLDEYWYYSVFTLSMLV---AFEASLVQ 282
E+ + +L ++ PF+VFQ F + LW Y YSV + + V ++
Sbjct: 187 AIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLR 246
Query: 283 QQMRNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIVPGDIVSIGRSPQENLVPCDVLLLR 342
QQ + + + NK + + + + + S +VPGDI+ + P + +PCD +L+
Sbjct: 247 QQSVKLHNLVEDHNKVQVTIIVKDKGLEELESRLLVPGDILIL---PGKFSLPCDAVLID 303
Query: 343 GRCIVDEAMLTGESVPQMKEPI---EDLSPDRVLDLQADSRLHVIFGGTKVVQHIPPQKA 399
G C+V+E MLTGES+P K P+ E+ P + L+ D R HV+F GT+V+Q
Sbjct: 304 GSCVVNEGMLTGESIPVTKTPLPQMENTMPWKCHSLE-DYRKHVLFCGTEVIQ------- 355
Query: 400 TTGLKPVDSGCV-AYVLRTGFNTSQGKLLRTILFGVKRVTANNLETFIFILFL-----LV 453
+KP G V A VL+TG+NT++G L+R+IL+ + F FI+FL +
Sbjct: 356 ---VKPSGQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACLGVMG 412
Query: 454 FAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYM 513
F A Y++ G P ++ + L ++LT VPP LP L++ + L K +
Sbjct: 413 FFYALGVYMY-HGV--PPKDTVTMAL---ILLTVTVPPVLPAALTIGNVYAQKRLKKKKI 466
Query: 514 YCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVAGLRDG----------KEVTPVSSI 563
+C P RI G++ + CFDKTGTLT D L + G D + P S +
Sbjct: 467 FCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVPTADNCFQEAHSFASGQAVPWSPL 526
Query: 564 PVETHRALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTLTK---DEKVFPRSIKT---QG 617
A+ASCHSL+ L+ GT+ GDPL+ M W + D F S+ G
Sbjct: 527 CA----AMASCHSLILLN-GTIQGDPLDLKMFEGTAWKMEDCIVDSCKFGTSVSNIIKPG 581
Query: 618 LKIHQ----------RFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPETLHSMFSQ- 666
K + +F F+S+L+RMSV+A + + + +KGAPE +
Sbjct: 582 PKASKSPVEAIITLCQFPFSSSLQRMSVIAQL----AGENHFHVYMKGAPEMVARFCRSE 637
Query: 667 -CPPDYHHIHTEISREGARVLALGYKELGHLTHQQAREVKREALECSLKFVGFIVVSCPL 725
P ++ + +G RV+AL +K L + + RE +E L F+G +++ L
Sbjct: 638 TVPKNFPQELRSYTVQGFRVIALAHKTLKMGNLSEVEHLAREKVESELTFLGLLIMENRL 697
Query: 726 KADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLIL----QPPSEKGRQ 781
K ++K V++E+ A R VMITGDN TA VA+ I +I+ +P
Sbjct: 698 KKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGSQVIIVEADEPEEFVPAS 757
Query: 782 CEWRSID------GSIVLPLARGSPKALALE----YALCLTGDGLAHLQATDPQQLLRLI 831
W+ ++ G + + G+ E Y ++G + L +++
Sbjct: 758 VTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYHFAMSGKSYQVIFQHFNSLLPKIL 817
Query: 832 PHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
+ VFAR++P QK +I ++L Y MCGDG ND GALK A G++L
Sbjct: 818 VNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISL 867
Score = 67.8 bits (164), Expect = 6e-11
Identities = 66/268 (24%), Positives = 117/268 (43%), Gaps = 29/268 (10%)
Query: 953 DASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKF 1012
+AS+A+PFTSK ++IQC+ H+I++GR LV++ +FK L + +I S +LY + F
Sbjct: 871 EASVASPFTSKTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFISALLLYWQLQLF 930
Query: 1013 SDFQATLQ--GLLLAGCFLFISRSKPLKTLSRERPLPNIFNLYTILTVML---------- 1060
++Q +Q + L C L +S + L+ RP + + +L++ L
Sbjct: 931 GNYQYLMQDVAITLMVC-LTMSSTHAYPKLAPYRPAGQLLSPPLLLSIFLNSCFSCIVQI 989
Query: 1061 QFFVH-----FLSLVYLYREAQARSPEKQEQFVDLYKEF--EPSLVNSTVYIMAMAMQMA 1113
F++ + VY Y E + V L + + +L+ ++
Sbjct: 990 SAFLYVKQQPWYCEVYQYSECFLANQSNFSTNVSLERNWTGNATLIPGSILSFETTTLWP 1049
Query: 1114 TFAINY--------KGPPFMESLPENKPLVWSLAVSLLAIIGLLLGSSPDFNSQFGLVDI 1165
INY KG PF + + N + L +L I +L L+
Sbjct: 1050 ITTINYITVAFIFSKGKPFRKPIYTNYIFSFLLLAALGLTIFILFSDFQVIYRGMELIPT 1109
Query: 1166 PVEFKLVIAQVLLLDFCLA-LLADRVLQ 1192
++++I V L FC+A + D +LQ
Sbjct: 1110 ITSWRVLILVVALTQFCVAFFVEDSILQ 1137
>gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]
Length = 1175
Score = 261 bits (666), Expect = 4e-69
Identities = 217/730 (29%), Positives = 355/730 (48%), Gaps = 83/730 (11%)
Query: 203 YQSNRGFQ-EDSEIRAAEKKFGSNKAEMVVPDFSELFKERATAPFFVFQVFCVGLWCLDE 261
++S G +D +R A +G N + V + +L + A P++ FQ F + LW D
Sbjct: 193 HRSRHGLSLQDQMVRKAI--YGPNVISIPVKSYPQLLVDEALNPYYGFQAFSIALWLADH 250
Query: 262 YWYYS--VFTLSML-VAFEASLVQQQMRNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIV 318
Y++Y+ +F +S + + ++Q + + ++ K+ + + + +W + S E+V
Sbjct: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEW--VDSSELV 308
Query: 319 PGDIVSIGRSPQEN-LVPCDVLLLRGRCIVDEAMLTGESVPQMKEPI-EDLSPDRVLDLQ 376
PGD + + PQE L+PCD L+ G C+V+E+ LTGES+P +K + E L P
Sbjct: 309 PGDCLVL---PQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPY----CA 361
Query: 377 ADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLRTILFGVKR 436
R H +F GT ++Q +A G +A V RTGF T++G L+ +IL
Sbjct: 362 ETHRRHTLFCGTLILQ----ARAYVG-----PHVLAVVTRTGFCTAKGGLVSSILHPRPI 412
Query: 437 VTANNLETFIFILFLLVFAIAAAAY-VWIEGTKDPSRNRYKL---FLECTLILTSVVPPE 492
+ F+ L V A+ Y ++I RNR L + ++T VVPP
Sbjct: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL-----YRNRVPLNEIVIRALDLVTVVVPPA 467
Query: 493 LPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVAGLR 552
LP +++ + L + ++C P RI GK+++ CFDKTGTLT D L V GV L+
Sbjct: 468 LPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLK 527
Query: 553 DGKEVTPVSSIPVETH-----RALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTLTKDEK 607
G+ P+ P RALA+CH+L +L D T VGDP++ M+ + W L ++E
Sbjct: 528 -GQAFLPLVPEPRRLPVGPLLRALATCHALSRLQD-TPVGDPMDLKMVESTGWVL-EEEP 584
Query: 608 VFPRSIKTQGLKIHQ----------------------RFHFASALKRMSVLASYEKLGST 645
+ TQ L + + RF F+SAL+RMSV+ ++
Sbjct: 585 AADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQP 644
Query: 646 DLCYIAAVKGAPETLHSMFSQ--CPPDYHHIHTEISREGARVLALGYKELGHLTH-QQAR 702
+ A VKG+PE + + + P D+ + + G RV+AL K L + + A+
Sbjct: 645 E----AYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQ 700
Query: 703 EVKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELH 762
++ R+ +E L +G +V+ LK + VI+ ++ R VM+TGDN TA VA+
Sbjct: 701 QLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCG 760
Query: 763 FIEKAHTLIL----QPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYA-------LCL 811
+ LI+ P + E+ ++ + + +A + L L
Sbjct: 761 MVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLAL 820
Query: 812 TGDGLAHLQATDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGA 871
+G + P+ L +++ VFAR+AP+QK ++ L++L Y MCGDG ND GA
Sbjct: 821 SGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGA 880
Query: 872 LKHADVGVAL 881
LK ADVG++L
Sbjct: 881 LKAADVGISL 890
Score = 82.4 bits (202), Expect = 2e-15
Identities = 67/256 (26%), Positives = 121/256 (47%), Gaps = 33/256 (12%)
Query: 953 DASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKF 1012
+AS+ +PFTS ++SI+C+ VI++GRC+L T+ +FK +AL +L S +LY
Sbjct: 894 EASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNL 953
Query: 1013 SDFQATLQGLLLAGCF-LFISRSKPLKTLSRERPLPNIFNLYTILTVMLQFFV------- 1064
D Q L++ + +SR+ P L R RP + ++ + +++LQ +
Sbjct: 954 GDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLG 1013
Query: 1065 -HFLSLVYLYREAQARSPEKQEQFVDLYKEFEPSLVNSTVYIMAMAMQMATFAINYKGPP 1123
+FL+L + R+ + P+ N+ V+ ++ + A KG P
Sbjct: 1014 GYFLTLAQPWFVPLNRTVAAPDNL--------PNYENTVVFSLSSFQYLILAAAVSKGAP 1065
Query: 1124 FMESLPENKPLVWSLAVSLLAIIGLLLGSSPDFNSQFGLVDIPVE--------FKLVIAQ 1175
F L N P + +LA+ ++GL+L GL+ P+ FKL++
Sbjct: 1066 FRRPLYTNVPFLVALALLSSVLVGLVLVP--------GLLQGPLALRNITDTGFKLLLLG 1117
Query: 1176 VLLLDFCLALLADRVL 1191
++ L+F A + + VL
Sbjct: 1118 LVTLNFVGAFMLESVL 1133
>gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens]
Length = 1180
Score = 261 bits (666), Expect = 4e-69
Identities = 217/730 (29%), Positives = 355/730 (48%), Gaps = 83/730 (11%)
Query: 203 YQSNRGFQ-EDSEIRAAEKKFGSNKAEMVVPDFSELFKERATAPFFVFQVFCVGLWCLDE 261
++S G +D +R A +G N + V + +L + A P++ FQ F + LW D
Sbjct: 198 HRSRHGLSLQDQMVRKAI--YGPNVISIPVKSYPQLLVDEALNPYYGFQAFSIALWLADH 255
Query: 262 YWYYS--VFTLSML-VAFEASLVQQQMRNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIV 318
Y++Y+ +F +S + + ++Q + + ++ K+ + + + +W + S E+V
Sbjct: 256 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEW--VDSSELV 313
Query: 319 PGDIVSIGRSPQEN-LVPCDVLLLRGRCIVDEAMLTGESVPQMKEPI-EDLSPDRVLDLQ 376
PGD + + PQE L+PCD L+ G C+V+E+ LTGES+P +K + E L P
Sbjct: 314 PGDCLVL---PQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPY----CA 366
Query: 377 ADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLRTILFGVKR 436
R H +F GT ++Q +A G +A V RTGF T++G L+ +IL
Sbjct: 367 ETHRRHTLFCGTLILQ----ARAYVG-----PHVLAVVTRTGFCTAKGGLVSSILHPRPI 417
Query: 437 VTANNLETFIFILFLLVFAIAAAAY-VWIEGTKDPSRNRYKL---FLECTLILTSVVPPE 492
+ F+ L V A+ Y ++I RNR L + ++T VVPP
Sbjct: 418 NFKFYKHSMKFVAALSVLALLGTIYSIFIL-----YRNRVPLNEIVIRALDLVTVVVPPA 472
Query: 493 LPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVAGLR 552
LP +++ + L + ++C P RI GK+++ CFDKTGTLT D L V GV L+
Sbjct: 473 LPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLK 532
Query: 553 DGKEVTPVSSIPVETH-----RALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTLTKDEK 607
G+ P+ P RALA+CH+L +L D T VGDP++ M+ + W L ++E
Sbjct: 533 -GQAFLPLVPEPRRLPVGPLLRALATCHALSRLQD-TPVGDPMDLKMVESTGWVL-EEEP 589
Query: 608 VFPRSIKTQGLKIHQ----------------------RFHFASALKRMSVLASYEKLGST 645
+ TQ L + + RF F+SAL+RMSV+ ++
Sbjct: 590 AADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQP 649
Query: 646 DLCYIAAVKGAPETLHSMFSQ--CPPDYHHIHTEISREGARVLALGYKELGHLTH-QQAR 702
+ A VKG+PE + + + P D+ + + G RV+AL K L + + A+
Sbjct: 650 E----AYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQ 705
Query: 703 EVKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELH 762
++ R+ +E L +G +V+ LK + VI+ ++ R VM+TGDN TA VA+
Sbjct: 706 QLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCG 765
Query: 763 FIEKAHTLIL----QPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYA-------LCL 811
+ LI+ P + E+ ++ + + +A + L L
Sbjct: 766 MVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLAL 825
Query: 812 TGDGLAHLQATDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGA 871
+G + P+ L +++ VFAR+AP+QK ++ L++L Y MCGDG ND GA
Sbjct: 826 SGPTFGIIVKHFPKLLPKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGA 885
Query: 872 LKHADVGVAL 881
LK ADVG++L
Sbjct: 886 LKAADVGISL 895
Score = 82.4 bits (202), Expect = 2e-15
Identities = 67/256 (26%), Positives = 121/256 (47%), Gaps = 33/256 (12%)
Query: 953 DASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKF 1012
+AS+ +PFTS ++SI+C+ VI++GRC+L T+ +FK +AL +L S +LY
Sbjct: 899 EASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNL 958
Query: 1013 SDFQATLQGLLLAGCF-LFISRSKPLKTLSRERPLPNIFNLYTILTVMLQFFV------- 1064
D Q L++ + +SR+ P L R RP + ++ + +++LQ +
Sbjct: 959 GDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLG 1018
Query: 1065 -HFLSLVYLYREAQARSPEKQEQFVDLYKEFEPSLVNSTVYIMAMAMQMATFAINYKGPP 1123
+FL+L + R+ + P+ N+ V+ ++ + A KG P
Sbjct: 1019 GYFLTLAQPWFVPLNRTVAAPDNL--------PNYENTVVFSLSSFQYLILAAAVSKGAP 1070
Query: 1124 FMESLPENKPLVWSLAVSLLAIIGLLLGSSPDFNSQFGLVDIPVE--------FKLVIAQ 1175
F L N P + +LA+ ++GL+L GL+ P+ FKL++
Sbjct: 1071 FRRPLYTNVPFLVALALLSSVLVGLVLVP--------GLLQGPLALRNITDTGFKLLLLG 1122
Query: 1176 VLLLDFCLALLADRVL 1191
++ L+F A + + VL
Sbjct: 1123 LVTLNFVGAFMLESVL 1138
>gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]
Length = 1158
Score = 254 bits (649), Expect = 3e-67
Identities = 214/719 (29%), Positives = 349/719 (48%), Gaps = 100/719 (13%)
Query: 203 YQSNRGFQ-EDSEIRAAEKKFGSNKAEMVVPDFSELFKERATAPFFVFQVFCVGLWCLDE 261
++S G +D +R A +G N + V + +L + A P++ FQ F + LW D
Sbjct: 193 HRSRHGLSLQDQMVRKAI--YGPNVISIPVKSYPQLLVDEALNPYYGFQAFSIALWLADH 250
Query: 262 YWYYS--VFTLSML-VAFEASLVQQQMRNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIV 318
Y++Y+ +F +S + + ++Q + + ++ K+ + + + +W + S E+V
Sbjct: 251 YYWYALCIFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEW--VDSSELV 308
Query: 319 PGDIVSIGRSPQEN-LVPCDVLLLRGRCIVDEAMLTGESVPQMKEPI-EDLSPDRVLDLQ 376
PGD + + PQE L+PCD L+ G C+V+E+ LTGES+P +K + E L P
Sbjct: 309 PGDCLVL---PQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPY----CA 361
Query: 377 ADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLRTILFGVKR 436
R H +F GT ++Q +A G +A V RTGF T++G L+ +IL
Sbjct: 362 ETHRRHTLFCGTLILQ----ARAYVG-----PHVLAVVTRTGFCTAKGGLVSSILHPRPI 412
Query: 437 VTANNLETFIFILFLLVFAIAAAAY-VWIEGTKDPSRNRYKL---FLECTLILTSVVPPE 492
+ F+ L V A+ Y ++I RNR L + ++T VVPP
Sbjct: 413 NFKFYKHSMKFVAALSVLALLGTIYSIFIL-----YRNRVPLNEIVIRALDLVTVVVPPA 467
Query: 493 LPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVAGLR 552
LP +++ + L + ++C P RI GK+++ CFDKTGTLT D L V GV L+
Sbjct: 468 LPAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLK 527
Query: 553 DGKEVTPV----SSIPV-ETHRALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTLTKDEK 607
G+ P+ +PV RALA+CH+L +L D T VGDP++ M+ + W L ++E
Sbjct: 528 -GQAFLPLVPEPRRLPVGPLLRALATCHALSRLQD-TPVGDPMDLKMVESTGWVL-EEEP 584
Query: 608 VFPRSIKTQGLKIHQ----------------------RFHFASALKRMSVLASYEKLGST 645
+ TQ L + + RF F+SAL+RMSV+ ++
Sbjct: 585 AADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQP 644
Query: 646 DLCYIAAVKGAPETLHSMFS--QCPPDYHHIHTEISREGARVLALGYKELGHL-THQQAR 702
+ A VKG+PE + + + P D+ + + G RV+AL K L + + + A+
Sbjct: 645 E----AYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLEAAQ 700
Query: 703 EVKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELH 762
++ R+ +E L +G +V+ LK + VI+ ++ R VM+TGDN TA VA+
Sbjct: 701 QLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCG 760
Query: 763 FIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQAT 822
+ LI+ + RG P +L +++
Sbjct: 761 MVAPQEHLIIVHATHP-----------------ERGQPASLE-----------FLPMESP 792
Query: 823 DPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
++++ VFAR+AP+QK ++ L++L Y MCGDG ND GALK ADVG++L
Sbjct: 793 TAVNGVKVLVQGTVFARMAPEQKTELVCELQKLQYCVGMCGDGANDCGALKAADVGISL 851
Score = 69.3 bits (168), Expect = 2e-11
Identities = 50/189 (26%), Positives = 90/189 (47%), Gaps = 17/189 (8%)
Query: 953 DASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKF 1012
+AS+ +PFTS ++SI+C+ VI++GRC+L T+ +FK +AL +L S +LY
Sbjct: 855 EASVVSPFTSSMASIECVPMVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNL 914
Query: 1013 SDFQATLQGLLLAGCF-LFISRSKPLKTLSRERPLPNIFNLYTILTVMLQFFV------- 1064
D Q L++ + +SR+ P L R RP + ++ + +++LQ +
Sbjct: 915 GDLQFLAIDLVITTTVAVLMSRTGPALVLGRVRPPGALLSVPVLSSLLLQMVLVTGVQLG 974
Query: 1065 -HFLSLVYLYREAQARSPEKQEQFVDLYKEFEPSLVNSTVYIMAMAMQMATFAINYKGPP 1123
+FL+L + R+ + P+ N+ V+ ++ + A KG P
Sbjct: 975 GYFLTLAQPWFVPLNRTVAAPDNL--------PNYENTVVFSLSSFQYLILAAAVSKGAP 1026
Query: 1124 FMESLPENK 1132
F L N+
Sbjct: 1027 FRRPLYTNE 1035
>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
sapiens]
Length = 1029
Score = 108 bits (271), Expect = 2e-23
Identities = 153/665 (23%), Positives = 270/665 (40%), Gaps = 111/665 (16%)
Query: 265 YSVFTLSMLVAFEASLVQQQMRNMSEIRKMGNK--PHMIQVYRSRKWRPIASDEIVPGDI 322
Y LS++V Q S+I + P V R + I E+V GD+
Sbjct: 139 YLSIVLSVVVIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDL 198
Query: 323 VSIGRSPQENLVPCDVLLLRGR-CIVDEAMLTGESVPQMKEPIEDLSPDRVLDLQADSRL 381
V I + VP D+ L+ + C VD + LTGES PQ + P D + + L+ +
Sbjct: 199 VEIKGGDR---VPADLRLISAQGCKVDNSSLTGESEPQSRSP--DFTHENPLETR----- 248
Query: 382 HVIFGGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKL--LRTILFGVKRVTA 439
++ F T V+ G+ V+ TG +T G++ L + L + A
Sbjct: 249 NICFFSTNCVEG-----TARGI----------VIATGDSTVMGRIASLTSGLAVGQTPIA 293
Query: 440 NNLETFIFILFLLV-------FAIAAA-AYVWIEGTKDPSRNRYKLFLECTLILTSVVPP 491
+E FI ++ ++ FA++ Y W+E +FL I+ + VP
Sbjct: 294 AEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAI---------IFL--IGIIVANVPE 342
Query: 492 ELPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGV--- 548
L +++ + + +A+ + G C DKTGTLT + + V +
Sbjct: 343 GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 402
Query: 549 --------AGLRDGKEVTPVSSIPVETHRALASCH--------SLMQLDDGTLVGDPLEK 592
+ GK T S R C+ ++ + GD E
Sbjct: 403 MTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIAKRATTGDASES 462
Query: 593 AMLTAVDWTLTKDEKVFPRSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAA 652
A+L ++ + + ++ ++ K + F S K + E T ++
Sbjct: 463 ALLKFIEQSYSSVAEMREKNPKVAEIP------FNSTNKYQMSIHLREDSSQT---HVLM 513
Query: 653 VKGAPETL-------------HSMFSQCPPDYHHIHTEISREGARVLALGYKELGHLTHQ 699
+KGAPE + +SM + + + + E+ G RVL + L +
Sbjct: 514 MKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPS-SFS 572
Query: 700 QAREVKREALEC---SLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACH 756
+ + + +L FVG I + P +A + + ++A +V+M+TGD+P+TA
Sbjct: 573 KGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKA 632
Query: 757 VAQELHFIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGL 816
+A+ + I SE E + + +P+++ A A+ + G L
Sbjct: 633 IAKGVGII-----------SEGTETAE--EVAARLKIPISKVDASAAK---AIVVHGAEL 676
Query: 817 AHLQATDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHAD 876
+Q+ Q+L+ P + VFAR +P+QK ++ + LG V + GDG ND ALK AD
Sbjct: 677 KDIQSKQLDQILQNHPEI-VFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKAD 735
Query: 877 VGVAL 881
+G+A+
Sbjct: 736 IGIAM 740
>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
Length = 1013
Score = 104 bits (259), Expect = 6e-22
Identities = 143/646 (22%), Positives = 260/646 (40%), Gaps = 105/646 (16%)
Query: 277 EASLVQQQMRNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIVPGDIVSIGRSPQENLVPC 336
++S + + +NM P V R + + ++E+V GD+V I + VP
Sbjct: 143 KSSKIMESFKNMV--------PQQALVIREGEKMQVNAEEVVVGDLVEIKGGDR---VPA 191
Query: 337 DVLLLRGR-CIVDEAMLTGESVPQMKEPIEDLSPDRVLDLQADSRLHVIFGGTKVVQHIP 395
D+ ++ C VD + LTGES PQ + SPD D ++R F V
Sbjct: 192 DLRIISAHGCKVDNSSLTGESEPQTR------SPDCTHDNPLETRNITFFSTNCVEGTAR 245
Query: 396 PQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLRTILFGVKRVTANNLETFIFILFLLVFA 455
TG + V G +A L +G + + I ++ +T + F+ + F ++
Sbjct: 246 GVVVATGDRTV-MGRIA-TLASGLEVGKTPIAIEIEHFIQLITG--VAVFLGVSFFILSL 301
Query: 456 IAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYMYC 515
I Y W+E +FL I+ + VP L +++ + + +A+
Sbjct: 302 ILG--YTWLEAV---------IFL--IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLV 348
Query: 516 TEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGV-----AGLRDGKEVTPVSSIPVETHRA 570
+ G C DKTGTLT + + V + D E +S +H
Sbjct: 349 KNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTW 408
Query: 571 LASCHSLMQLDDGT--------------LVGDPLEKAMLTAVDWTLTKDEKVFPRSIKTQ 616
+A H + + GD E A+L ++ + + + R+ K
Sbjct: 409 VALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVA 468
Query: 617 GLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPETLHSMFS-------QCPP 669
+ + + L+ +E D Y+ +KGAPE + S + P
Sbjct: 469 EIPFNSTNKYQ--------LSIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPL 520
Query: 670 D------YHHIHTEISREGARVLALGYKELGHLTHQQAREVKREALEC--------SLKF 715
D + + + E+ G RVL + L + + K A +C +L F
Sbjct: 521 DEEMKEAFQNAYLELGGLGERVLGFCHYYL-----PEEQFPKGFAFDCDDVNFTTDNLCF 575
Query: 716 VGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLILQPP 775
VG + + P +A + + ++A +V+M+TGD+P+TA +A+ + I + + +
Sbjct: 576 VGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV---- 631
Query: 776 SEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQATDPQQLLRLIPHVQ 835
I + +P+++ +P+ A + G L + ++L+ +
Sbjct: 632 ---------EDIAARLNIPVSQVNPRDAK---ACVIHGTDLKDFTSEQIDEILQNHTEI- 678
Query: 836 VFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
VFAR +P+QK ++ + G + + GDG ND ALK AD+GVA+
Sbjct: 679 VFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAM 724
>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo
sapiens]
Length = 1023
Score = 103 bits (256), Expect = 1e-21
Identities = 139/647 (21%), Positives = 260/647 (40%), Gaps = 107/647 (16%)
Query: 277 EASLVQQQMRNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIVPGDIVSIGRSPQENLVPC 336
++S + + +NM P V R+ + I ++E+V GD+V + + +P
Sbjct: 153 KSSKIMESFKNMV--------PQQALVIRNGEKMSINAEEVVVGDLVEVKGGDR---IPA 201
Query: 337 DVLLLRGR-CIVDEAMLTGESVPQMKEPIEDLSPDRVLDLQADSRLHVIFGGTKVVQHIP 395
D+ ++ C VD + LTGES PQ + P D + + L+ + ++ F T V+
Sbjct: 202 DLRIISANGCKVDNSSLTGESEPQTRSP--DFTNENPLETR-----NIAFFSTNCVEGTA 254
Query: 396 PQKATTGLKPVDSGCVAYVLRTGFNTSQGKL--LRTILFGVKRVTANNLETFIFILFLLV 453
G V Y TG T G++ L + L G + A +E FI I+ +
Sbjct: 255 ------------RGIVVY---TGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVA 299
Query: 454 FAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYM 513
+ + ++ S +LE + L ++ +P L V L AK
Sbjct: 300 VFLGVSFFIL-------SLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMA 352
Query: 514 ----YCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGV-----------AGLRDGKEVT 558
+ G C DKTGTLT + + V + + G
Sbjct: 353 RKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFD 412
Query: 559 PVSSIPVETHRALASCH-SLMQLDDGTL-------VGDPLEKAMLTAVDWTLTKDEKVFP 610
S+ + R C+ ++ Q + L GD E A+L ++ +++
Sbjct: 413 KTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRE 472
Query: 611 RSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPETLHSMFSQC--- 667
R K + + + L+ ++ +++ ++ +KGAPE + S
Sbjct: 473 RYAKIVEIPFNSTNKYQ--------LSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLH 524
Query: 668 ----PPD------YHHIHTEISREGARVLALGYKELGHLTHQQAREVKREALEC---SLK 714
P D + + + E+ G RVL + L + + + + +L
Sbjct: 525 GKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLC 584
Query: 715 FVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLILQP 774
FVG I + P +A + + ++A +V+M+TGD+P+TA +A+ + I + + +
Sbjct: 585 FVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV--- 641
Query: 775 PSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQATDPQQLLRLIPHV 834
I + +P+++ +P+ A + G L + + +L+ +
Sbjct: 642 ----------EDIAARLNIPVSQVNPRDAK---ACVVHGSDLKDMTSEQLDDILKYHTEI 688
Query: 835 QVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
VFAR +P+QK ++ + G + + GDG ND ALK AD+GVA+
Sbjct: 689 -VFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAM 734
>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
Length = 1020
Score = 103 bits (256), Expect = 1e-21
Identities = 138/623 (22%), Positives = 260/623 (41%), Gaps = 94/623 (15%)
Query: 298 PHMIQVYRSRKWRPIASDEIVPGDIVSIGRSPQENLVPCDVLLLRGR-CIVDEAMLTGES 356
P V R + I ++E+V GD+V + + VP D+ ++ C VD + LTGES
Sbjct: 164 PQQALVIREGEKMQINAEEVVVGDLVEVKGGDR---VPADLRIISSHGCKVDNSSLTGES 220
Query: 357 VPQMKEPIEDLSPDRVLDLQADSRLHVIFGGTKVVQHIPPQKA-TTGLKPVDSGCVAYVL 415
PQ + P + + + L+ + ++ F T V+ TG + V G +A L
Sbjct: 221 EPQTRSP--EFTHENPLETR-----NICFFSTNCVEGTARGIVIATGDRTV-MGRIA-TL 271
Query: 416 RTGFNTSQGKLLRTILFGVKRVTANNLETFIFILFLLVFAIAAAAYVWIEGTKDPSRNRY 475
+G + + I ++ +T + F+ + F ++ I Y W+E
Sbjct: 272 ASGLEVGRTPIAMEIEHFIQLITG--VAVFLGVSFFVLSLILG--YSWLEAV-------- 319
Query: 476 KLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKT 535
+FL I+ + VP L +++ + + +A+ + G C DKT
Sbjct: 320 -IFL--IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKT 376
Query: 536 GTLTSDSLVVR------------------GVAGLRDGKEVTPVSSIPVETHRALASC-HS 576
GTLT + + V G + T +S I +RA+
Sbjct: 377 GTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQE 436
Query: 577 LMQLDDGTLVGDPLEKAMLTAVDWTLTKDEKVFPRSIKTQGLKIHQRFHFASALKRMSVL 636
+ + GD E A+L ++ + K+ R+ K + + + L
Sbjct: 437 NISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQ--------L 488
Query: 637 ASYEKLGSTDLCYIAAVKGAPETLHSMFS-------QCPPD------YHHIHTEISREGA 683
+ +E+ S ++ +KGAPE + S + P D + + + E+ G
Sbjct: 489 SIHEREDSPQ-SHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGE 547
Query: 684 RVLALGYKELGHLTHQQAREVKREALECS-----LKFVGFIVVSCPLKADSKAVIREIQN 738
RVL G+ +L + + R K + E + L FVG + + P +A + + ++
Sbjct: 548 RVL--GFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRS 605
Query: 739 ASHRVVMITGDNPLTACHVAQELHFIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARG 798
A +V+M+TGD+P+TA +A+ + I + + + I + +P+++
Sbjct: 606 AGIKVIMVTGDHPITAKAIAKGVGIISEGNETV-------------EDIAARLNIPMSQV 652
Query: 799 SPKALALEYALCLTGDGLAHLQATDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYV 858
+P+ A + G L + + ++L+ + VFAR +P+QK ++ + G +
Sbjct: 653 NPREAK---ACVVHGSDLKDMTSEQLDEILKNHTEI-VFARTSPQQKLIIVEGCQRQGAI 708
Query: 859 TLMCGDGTNDVGALKHADVGVAL 881
+ GDG ND ALK AD+G+A+
Sbjct: 709 VAVTGDGVNDSPALKKADIGIAM 731
>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo
sapiens]
Length = 992
Score = 103 bits (256), Expect = 1e-21
Identities = 139/647 (21%), Positives = 260/647 (40%), Gaps = 107/647 (16%)
Query: 277 EASLVQQQMRNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIVPGDIVSIGRSPQENLVPC 336
++S + + +NM P V R+ + I ++E+V GD+V + + +P
Sbjct: 122 KSSKIMESFKNMV--------PQQALVIRNGEKMSINAEEVVVGDLVEVKGGDR---IPA 170
Query: 337 DVLLLRGR-CIVDEAMLTGESVPQMKEPIEDLSPDRVLDLQADSRLHVIFGGTKVVQHIP 395
D+ ++ C VD + LTGES PQ + P D + + L+ + ++ F T V+
Sbjct: 171 DLRIISANGCKVDNSSLTGESEPQTRSP--DFTNENPLETR-----NIAFFSTNCVEGTA 223
Query: 396 PQKATTGLKPVDSGCVAYVLRTGFNTSQGKL--LRTILFGVKRVTANNLETFIFILFLLV 453
G V Y TG T G++ L + L G + A +E FI I+ +
Sbjct: 224 ------------RGIVVY---TGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVA 268
Query: 454 FAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYM 513
+ + ++ S +LE + L ++ +P L V L AK
Sbjct: 269 VFLGVSFFIL-------SLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMA 321
Query: 514 ----YCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGV-----------AGLRDGKEVT 558
+ G C DKTGTLT + + V + + G
Sbjct: 322 RKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFD 381
Query: 559 PVSSIPVETHRALASCH-SLMQLDDGTL-------VGDPLEKAMLTAVDWTLTKDEKVFP 610
S+ + R C+ ++ Q + L GD E A+L ++ +++
Sbjct: 382 KTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRE 441
Query: 611 RSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPETLHSMFSQC--- 667
R K + + + L+ ++ +++ ++ +KGAPE + S
Sbjct: 442 RYAKIVEIPFNSTNKYQ--------LSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLH 493
Query: 668 ----PPD------YHHIHTEISREGARVLALGYKELGHLTHQQAREVKREALEC---SLK 714
P D + + + E+ G RVL + L + + + + +L
Sbjct: 494 GKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLC 553
Query: 715 FVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLILQP 774
FVG I + P +A + + ++A +V+M+TGD+P+TA +A+ + I + + +
Sbjct: 554 FVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV--- 610
Query: 775 PSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQATDPQQLLRLIPHV 834
I + +P+++ +P+ A + G L + + +L+ +
Sbjct: 611 ----------EDIAARLNIPVSQVNPRDAK---ACVVHGSDLKDMTSEQLDDILKYHTEI 657
Query: 835 QVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
VFAR +P+QK ++ + G + + GDG ND ALK AD+GVA+
Sbjct: 658 -VFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAM 703
>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
Length = 1023
Score = 103 bits (256), Expect = 1e-21
Identities = 139/647 (21%), Positives = 260/647 (40%), Gaps = 107/647 (16%)
Query: 277 EASLVQQQMRNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIVPGDIVSIGRSPQENLVPC 336
++S + + +NM P V R+ + I ++E+V GD+V + + +P
Sbjct: 153 KSSKIMESFKNMV--------PQQALVIRNGEKMSINAEEVVVGDLVEVKGGDR---IPA 201
Query: 337 DVLLLRGR-CIVDEAMLTGESVPQMKEPIEDLSPDRVLDLQADSRLHVIFGGTKVVQHIP 395
D+ ++ C VD + LTGES PQ + P D + + L+ + ++ F T V+
Sbjct: 202 DLRIISANGCKVDNSSLTGESEPQTRSP--DFTNENPLETR-----NIAFFSTNCVEGTA 254
Query: 396 PQKATTGLKPVDSGCVAYVLRTGFNTSQGKL--LRTILFGVKRVTANNLETFIFILFLLV 453
G V Y TG T G++ L + L G + A +E FI I+ +
Sbjct: 255 ------------RGIVVY---TGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVA 299
Query: 454 FAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYM 513
+ + ++ S +LE + L ++ +P L V L AK
Sbjct: 300 VFLGVSFFIL-------SLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMA 352
Query: 514 ----YCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGV-----------AGLRDGKEVT 558
+ G C DKTGTLT + + V + + G
Sbjct: 353 RKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFD 412
Query: 559 PVSSIPVETHRALASCH-SLMQLDDGTL-------VGDPLEKAMLTAVDWTLTKDEKVFP 610
S+ + R C+ ++ Q + L GD E A+L ++ +++
Sbjct: 413 KTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRE 472
Query: 611 RSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPETLHSMFSQC--- 667
R K + + + L+ ++ +++ ++ +KGAPE + S
Sbjct: 473 RYAKIVEIPFNSTNKYQ--------LSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLH 524
Query: 668 ----PPD------YHHIHTEISREGARVLALGYKELGHLTHQQAREVKREALEC---SLK 714
P D + + + E+ G RVL + L + + + + +L
Sbjct: 525 GKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLC 584
Query: 715 FVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLILQP 774
FVG I + P +A + + ++A +V+M+TGD+P+TA +A+ + I + + +
Sbjct: 585 FVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV--- 641
Query: 775 PSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQATDPQQLLRLIPHV 834
I + +P+++ +P+ A + G L + + +L+ +
Sbjct: 642 ----------EDIAARLNIPVSQVNPRDAK---ACVVHGSDLKDMTSEQLDDILKYHTEI 688
Query: 835 QVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
VFAR +P+QK ++ + G + + GDG ND ALK AD+GVA+
Sbjct: 689 -VFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAM 734
>gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]
Length = 1035
Score = 99.8 bits (247), Expect = 1e-20
Identities = 148/662 (22%), Positives = 259/662 (39%), Gaps = 94/662 (14%)
Query: 260 DEYWYYSVFTLSMLVAFEASLVQQQMRNMSEIRKMGNK-PHMIQVYRSRKWRPIASDEIV 318
D+ Y ++ ++++V Q+ ++ + I N P V R I +D++V
Sbjct: 138 DDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLV 197
Query: 319 PGDIVSIGRSPQENLVPCDVLLLRGR-CIVDEAMLTGESVPQMKEPIEDLSPDRVLDLQA 377
GD+V + + VP D+ +L + C VD + LTGES PQ + SP+ +
Sbjct: 198 VGDLVEMKGGDR---VPADIRILAAQGCKVDNSSLTGESEPQTR------SPECTHESPL 248
Query: 378 DSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLRTILFGV--- 434
++R ++ F T ++ GL V+ TG T G++ ++ GV
Sbjct: 249 ETR-NIAFFSTMCLEG-----TVQGL----------VVNTGDRTIIGRIA-SLASGVENE 291
Query: 435 KRVTANNLETFIFILFLLVFAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELP 494
K A +E F+ I+ L A ++ F+ I+ + VP L
Sbjct: 292 KTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMA---IVVAYVPEGLL 348
Query: 495 IELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGV------ 548
+++ ++ + LA + G V C DKTGTLT + + V +
Sbjct: 349 ATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHI 408
Query: 549 -----AGLRDGKEVTPVSSIPVETHRALASCH--------SLMQLDDGTLVGDPLEKAML 595
+ G+ S R L C+ + + ++GD E A+L
Sbjct: 409 HTADTTEDQSGQTFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALL 468
Query: 596 TAVDWTLTKDEKVFPRSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKG 655
+ TL R K + + F ++ + D ++ +KG
Sbjct: 469 KFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLE--------DPRDPRHLLVMKG 520
Query: 656 APETLHSMFS-------QCPPD------YHHIHTEISREGARVLALGYKELGHLTHQQAR 702
APE + S + P D + + + G RVL L +
Sbjct: 521 APERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGY 580
Query: 703 EVKREALE---CSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQ 759
EA+ L F G + + P +A + + + A RV+M+TGD+P+TA +A
Sbjct: 581 AFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAA 640
Query: 760 ELHFIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHL 819
+ I + + I + +P+ + + K A + G L +
Sbjct: 641 SVGIISEGSETV-------------EDIAARLRVPVDQVNRKDAR---ACVINGMQLKDM 684
Query: 820 QATDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGV 879
++ + LR P + VFAR +P+QK ++ S + LG + + GDG ND ALK AD+GV
Sbjct: 685 DPSELVEALRTHPEM-VFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGV 743
Query: 880 AL 881
A+
Sbjct: 744 AM 745
>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
Length = 1039
Score = 97.1 bits (240), Expect = 9e-20
Identities = 146/666 (21%), Positives = 264/666 (39%), Gaps = 121/666 (18%)
Query: 270 LSMLVAFEASLVQQQMRNMSEIRKMGNK--PHMIQVYRSRKWRPIASDEIVPGDIVSIGR 327
L ++V Q + I NK P V R + + I S+++V GDIV +
Sbjct: 151 LGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKG 210
Query: 328 SPQENLVPCDVLLLRGR-CIVDEAMLTGESVPQMKEPIEDLSPDRVLDLQADSRLHVIFG 386
Q +P D+ +L + C VD + LTGES PQ + + + + L+ + ++ F
Sbjct: 211 GDQ---IPADIRVLSSQGCRVDNSSLTGESEPQPRS--SEFTHENPLETK-----NICFY 260
Query: 387 GTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLRTILFGV---KRVTANNLE 443
T ++ TG+ V+ TG T G + ++ GV K A +E
Sbjct: 261 STTCLEG-----TVTGM----------VINTGDRTIIGHIA-SLASGVGNEKTPIAIEIE 304
Query: 444 TFIFILFLLVFAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIEL--SLAV 501
F+ I+ + +I ++ K Y++ L+ + L ++ +P L ++ V
Sbjct: 305 HFVHIVAGVAVSIGILFFIIAVSLK------YQV-LDSIIFLIGIIVANVPEGLLATVTV 357
Query: 502 NTSLIA--LAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGV-----AGLRDG 554
SL A +AK + G + C DKTGTLT + + V + + D
Sbjct: 358 TLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADT 417
Query: 555 KEVTPVSSIPVETHRALASCHSLMQLDD---------------GTLVGDPLEKAMLTAVD 599
E + + ++ R AS ++ L + ++GD E A+L +
Sbjct: 418 SE-DHSNQVFDQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSE 476
Query: 600 WTLTKDEKVFPRSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPET 659
L ++ R+ K + + F ++ M + G ++ +KGAPE
Sbjct: 477 VILGDVMEIRKRNRKVAEIPFNSTNKFQLSIHEMD-----DPHGKR---FLMVMKGAPER 528
Query: 660 L-------------HSMFSQCPPDYHHIHTEISREGARVLALGYKELGHLTHQQAREVKR 706
+ H + +H + E+ G RVL + L +
Sbjct: 529 ILEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDI 588
Query: 707 EALE---CSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHF 763
+A+ +L FVG + + P ++ + + ++A +V+M+TGD+P+TA +A+ +
Sbjct: 589 DAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGI 648
Query: 764 I--------EKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDG 815
I + AH L + R + A +TG
Sbjct: 649 ISANSETVEDIAHRLNIAVEQVNKRDAK------------------------AAVVTGME 684
Query: 816 LAHLQATDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHA 875
L + + ++L + VFAR +P+QK ++ + V + GDG ND ALK A
Sbjct: 685 LKDMSSEQLDEILANYQEI-VFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKA 743
Query: 876 DVGVAL 881
D+G+A+
Sbjct: 744 DIGIAM 749
>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo
sapiens]
Length = 939
Score = 89.7 bits (221), Expect = 1e-17
Identities = 152/660 (23%), Positives = 252/660 (38%), Gaps = 152/660 (23%)
Query: 269 TLSMLVAFEASLVQQQM--RNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIVPGDIVSIG 326
T+++L+ + VQ+ +++ E+ K+ P R K + ++VPGD V +
Sbjct: 107 TVAILIVVTVAFVQEYRSEKSLEELSKL--VPPECHCVREGKLEHTLARDLVPGDTVCLS 164
Query: 327 RSPQENLVPCDVLLLRGRCI-VDEAMLTGESVPQMKEPIEDLSPDRVLDLQADSRLHVIF 385
+ VP D+ L + +DE+ LTGE+ P K + DL SR ++ F
Sbjct: 165 VGDR---VPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNG-DLA--SRSNIAF 218
Query: 386 GGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLR---------TILFGVKR 436
GT V V+ TG N+ G++ + T L
Sbjct: 219 MGTLVRC---------------GKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMD 263
Query: 437 VTANNLETFIFILFLLVFAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIE 496
+ L + F + ++ + W+ G ++ ++F + + +P LPI
Sbjct: 264 LLGKQLSFYSFGIIGIIMLVG-----WLLG-----KDILEMFTISVSLAVAAIPEGLPIV 313
Query: 497 LSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVA---GLR- 552
+++ + ++ + K + + G V C DKTGTLT + + V + GL
Sbjct: 314 VTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHA 373
Query: 553 ---------------DGKEV----TPVSSIPVETHRALASCHSLMQLDDGTLVGDPLEKA 593
DG V P S VE A C+ + + + TL+G P E A
Sbjct: 374 EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVE---AGCVCNDAV-IRNNTLMGKPTEGA 429
Query: 594 MLTAV----------DWTLTKDEKVFPRSIKTQGLK-IHQRFHFASALKRMSVLASYEKL 642
++ D+ + K E F K +K +H+ + M +YE++
Sbjct: 430 LIALAMKMGLDGLQQDY-IRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK--GAYEQV 486
Query: 643 GSTDLCYIAAVKGAPETLHSMFSQCPPDYHHIHTEISREGARVLALGY-KELGHLTHQQA 701
+ Y + +TL ++ Q Y + G RVLAL ELG LT
Sbjct: 487 ----IKYCTTYQSKGQTL-TLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLT---- 537
Query: 702 REVKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQEL 761
F+G + + P + K + + + + MITGD+ TA +A L
Sbjct: 538 -------------FLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRL 584
Query: 762 HFIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQA 821
K +S+ G + A
Sbjct: 585 GLYSKTS----------------QSVSGE---------------------------EIDA 601
Query: 822 TDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
D QQL +++P V VF R +P+ K +I SL++ G V M GDG ND ALK AD+GVA+
Sbjct: 602 MDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAM 661
>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo
sapiens]
Length = 949
Score = 89.7 bits (221), Expect = 1e-17
Identities = 152/660 (23%), Positives = 252/660 (38%), Gaps = 152/660 (23%)
Query: 269 TLSMLVAFEASLVQQQM--RNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIVPGDIVSIG 326
T+++L+ + VQ+ +++ E+ K+ P R K + ++VPGD V +
Sbjct: 107 TVAILIVVTVAFVQEYRSEKSLEELSKL--VPPECHCVREGKLEHTLARDLVPGDTVCLS 164
Query: 327 RSPQENLVPCDVLLLRGRCI-VDEAMLTGESVPQMKEPIEDLSPDRVLDLQADSRLHVIF 385
+ VP D+ L + +DE+ LTGE+ P K + DL SR ++ F
Sbjct: 165 VGDR---VPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNG-DLA--SRSNIAF 218
Query: 386 GGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLR---------TILFGVKR 436
GT V V+ TG N+ G++ + T L
Sbjct: 219 MGTLVRC---------------GKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMD 263
Query: 437 VTANNLETFIFILFLLVFAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIE 496
+ L + F + ++ + W+ G ++ ++F + + +P LPI
Sbjct: 264 LLGKQLSFYSFGIIGIIMLVG-----WLLG-----KDILEMFTISVSLAVAAIPEGLPIV 313
Query: 497 LSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVA---GLR- 552
+++ + ++ + K + + G V C DKTGTLT + + V + GL
Sbjct: 314 VTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHA 373
Query: 553 ---------------DGKEV----TPVSSIPVETHRALASCHSLMQLDDGTLVGDPLEKA 593
DG V P S VE A C+ + + + TL+G P E A
Sbjct: 374 EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVE---AGCVCNDAV-IRNNTLMGKPTEGA 429
Query: 594 MLTAV----------DWTLTKDEKVFPRSIKTQGLK-IHQRFHFASALKRMSVLASYEKL 642
++ D+ + K E F K +K +H+ + M +YE++
Sbjct: 430 LIALAMKMGLDGLQQDY-IRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK--GAYEQV 486
Query: 643 GSTDLCYIAAVKGAPETLHSMFSQCPPDYHHIHTEISREGARVLALGY-KELGHLTHQQA 701
+ Y + +TL ++ Q Y + G RVLAL ELG LT
Sbjct: 487 ----IKYCTTYQSKGQTL-TLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLT---- 537
Query: 702 REVKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQEL 761
F+G + + P + K + + + + MITGD+ TA +A L
Sbjct: 538 -------------FLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRL 584
Query: 762 HFIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQA 821
K +S+ G + A
Sbjct: 585 GLYSKTS----------------QSVSGE---------------------------EIDA 601
Query: 822 TDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
D QQL +++P V VF R +P+ K +I SL++ G V M GDG ND ALK AD+GVA+
Sbjct: 602 MDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAM 661
>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo
sapiens]
Length = 888
Score = 89.7 bits (221), Expect = 1e-17
Identities = 152/660 (23%), Positives = 252/660 (38%), Gaps = 152/660 (23%)
Query: 269 TLSMLVAFEASLVQQQM--RNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIVPGDIVSIG 326
T+++L+ + VQ+ +++ E+ K+ P R K + ++VPGD V +
Sbjct: 107 TVAILIVVTVAFVQEYRSEKSLEELSKL--VPPECHCVREGKLEHTLARDLVPGDTVCLS 164
Query: 327 RSPQENLVPCDVLLLRGRCI-VDEAMLTGESVPQMKEPIEDLSPDRVLDLQADSRLHVIF 385
+ VP D+ L + +DE+ LTGE+ P K + DL SR ++ F
Sbjct: 165 VGDR---VPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNG-DLA--SRSNIAF 218
Query: 386 GGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLR---------TILFGVKR 436
GT V V+ TG N+ G++ + T L
Sbjct: 219 MGTLVRC---------------GKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMD 263
Query: 437 VTANNLETFIFILFLLVFAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIE 496
+ L + F + ++ + W+ G ++ ++F + + +P LPI
Sbjct: 264 LLGKQLSFYSFGIIGIIMLVG-----WLLG-----KDILEMFTISVSLAVAAIPEGLPIV 313
Query: 497 LSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVA---GLR- 552
+++ + ++ + K + + G V C DKTGTLT + + V + GL
Sbjct: 314 VTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHA 373
Query: 553 ---------------DGKEV----TPVSSIPVETHRALASCHSLMQLDDGTLVGDPLEKA 593
DG V P S VE A C+ + + + TL+G P E A
Sbjct: 374 EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVE---AGCVCNDAV-IRNNTLMGKPTEGA 429
Query: 594 MLTAV----------DWTLTKDEKVFPRSIKTQGLK-IHQRFHFASALKRMSVLASYEKL 642
++ D+ + K E F K +K +H+ + M +YE++
Sbjct: 430 LIALAMKMGLDGLQQDY-IRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK--GAYEQV 486
Query: 643 GSTDLCYIAAVKGAPETLHSMFSQCPPDYHHIHTEISREGARVLALGY-KELGHLTHQQA 701
+ Y + +TL ++ Q Y + G RVLAL ELG LT
Sbjct: 487 ----IKYCTTYQSKGQTL-TLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLT---- 537
Query: 702 REVKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQEL 761
F+G + + P + K + + + + MITGD+ TA +A L
Sbjct: 538 -------------FLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRL 584
Query: 762 HFIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQA 821
K +S+ G + A
Sbjct: 585 GLYSKTS----------------QSVSGE---------------------------EIDA 601
Query: 822 TDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
D QQL +++P V VF R +P+ K +I SL++ G V M GDG ND ALK AD+GVA+
Sbjct: 602 MDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAM 661
>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo
sapiens]
Length = 919
Score = 89.7 bits (221), Expect = 1e-17
Identities = 152/660 (23%), Positives = 252/660 (38%), Gaps = 152/660 (23%)
Query: 269 TLSMLVAFEASLVQQQM--RNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIVPGDIVSIG 326
T+++L+ + VQ+ +++ E+ K+ P R K + ++VPGD V +
Sbjct: 107 TVAILIVVTVAFVQEYRSEKSLEELSKL--VPPECHCVREGKLEHTLARDLVPGDTVCLS 164
Query: 327 RSPQENLVPCDVLLLRGRCI-VDEAMLTGESVPQMKEPIEDLSPDRVLDLQADSRLHVIF 385
+ VP D+ L + +DE+ LTGE+ P K + DL SR ++ F
Sbjct: 165 VGDR---VPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNG-DLA--SRSNIAF 218
Query: 386 GGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLR---------TILFGVKR 436
GT V V+ TG N+ G++ + T L
Sbjct: 219 MGTLVRC---------------GKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMD 263
Query: 437 VTANNLETFIFILFLLVFAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIE 496
+ L + F + ++ + W+ G ++ ++F + + +P LPI
Sbjct: 264 LLGKQLSFYSFGIIGIIMLVG-----WLLG-----KDILEMFTISVSLAVAAIPEGLPIV 313
Query: 497 LSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVA---GLR- 552
+++ + ++ + K + + G V C DKTGTLT + + V + GL
Sbjct: 314 VTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHA 373
Query: 553 ---------------DGKEV----TPVSSIPVETHRALASCHSLMQLDDGTLVGDPLEKA 593
DG V P S VE A C+ + + + TL+G P E A
Sbjct: 374 EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVE---AGCVCNDAV-IRNNTLMGKPTEGA 429
Query: 594 MLTAV----------DWTLTKDEKVFPRSIKTQGLK-IHQRFHFASALKRMSVLASYEKL 642
++ D+ + K E F K +K +H+ + M +YE++
Sbjct: 430 LIALAMKMGLDGLQQDY-IRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK--GAYEQV 486
Query: 643 GSTDLCYIAAVKGAPETLHSMFSQCPPDYHHIHTEISREGARVLALGY-KELGHLTHQQA 701
+ Y + +TL ++ Q Y + G RVLAL ELG LT
Sbjct: 487 ----IKYCTTYQSKGQTL-TLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLT---- 537
Query: 702 REVKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQEL 761
F+G + + P + K + + + + MITGD+ TA +A L
Sbjct: 538 -------------FLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRL 584
Query: 762 HFIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQA 821
K +S+ G + A
Sbjct: 585 GLYSKTS----------------QSVSGE---------------------------EIDA 601
Query: 822 TDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
D QQL +++P V VF R +P+ K +I SL++ G V M GDG ND ALK AD+GVA+
Sbjct: 602 MDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAM 661
>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b
[Homo sapiens]
Length = 994
Score = 86.3 bits (212), Expect = 2e-16
Identities = 158/666 (23%), Positives = 251/666 (37%), Gaps = 149/666 (22%)
Query: 297 KPHMIQVYRS--RKWRPIASDEIVPGDIVSIGRSPQENLVPCDVLLLRGRCI---VDEAM 351
+P M +VYR+ + + I + +IVPGDIV + + VP D+ +L + VD+++
Sbjct: 123 EPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDK---VPADIRILAIKSTTLRVDQSI 179
Query: 352 LTGESVPQMK--EPIEDLSPDRVLDLQADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSG 409
LTGESV +K EP+ D R ++ + +++F GT +
Sbjct: 180 LTGESVSVIKHTEPVPD---PRAVN---QDKKNMLFSGTNIAA---------------GK 218
Query: 410 CVAYVLRTGFNTSQGKLLRTILFGVKRVTA--NNLETFIFILFLLVFAIAAAAY-VWIEG 466
+ V TG T GK+ + + T L+ F L ++ I A + + I
Sbjct: 219 ALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGH 278
Query: 467 TKDPS------RNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFR 520
DP R F + + +P LP ++ + +AK
Sbjct: 279 FNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPS 338
Query: 521 IPFAGKVEVCCFDKTGTLTSDSL------VVRGVAG---------------------LRD 553
+ G V C DKTGTLT++ + ++ V G L++
Sbjct: 339 VETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKN 398
Query: 554 GKEVTPVS-SIPVETHRALASCH-SLMQLDDG----TLVGDPLEKAMLTAVD-------- 599
K V P VE A C+ S + ++ VG+ E A+ T V+
Sbjct: 399 DKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTD 458
Query: 600 -WTLTKDEKVFP-RSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAP 657
+L+K E+ S+ Q +K F+ K MSV S K + VKGAP
Sbjct: 459 VRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAP 518
Query: 658 ETLHSMFSQCPPDYHHIHTE--------------------ISREGARVLALGYKELGHLT 697
E + +C +Y + T R+ R LAL ++
Sbjct: 519 E---GVIDRC--NYVRVGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKR 573
Query: 698 HQQAREVKREAL--ECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTAC 755
+ + L E L FVG + + P + + I+ ++A RV+MITGDN TA
Sbjct: 574 EEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAI 633
Query: 756 HVAQELHFIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDG 815
+ + + + + R R D LPLA + A A C
Sbjct: 634 AICRRIGIFGENEEV-------ADRAYTGREFDD---LPLAE---QREACRRACC----- 675
Query: 816 LAHLQATDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHA 875
FARV P K ++ L+ +T M GDG ND ALK A
Sbjct: 676 ---------------------FARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKA 714
Query: 876 DVGVAL 881
++G+A+
Sbjct: 715 EIGIAM 720
>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a
[Homo sapiens]
Length = 1001
Score = 86.3 bits (212), Expect = 2e-16
Identities = 158/666 (23%), Positives = 251/666 (37%), Gaps = 149/666 (22%)
Query: 297 KPHMIQVYRS--RKWRPIASDEIVPGDIVSIGRSPQENLVPCDVLLLRGRCI---VDEAM 351
+P M +VYR+ + + I + +IVPGDIV + + VP D+ +L + VD+++
Sbjct: 123 EPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDK---VPADIRILAIKSTTLRVDQSI 179
Query: 352 LTGESVPQMK--EPIEDLSPDRVLDLQADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSG 409
LTGESV +K EP+ D R ++ + +++F GT +
Sbjct: 180 LTGESVSVIKHTEPVPD---PRAVN---QDKKNMLFSGTNIAA---------------GK 218
Query: 410 CVAYVLRTGFNTSQGKLLRTILFGVKRVTA--NNLETFIFILFLLVFAIAAAAY-VWIEG 466
+ V TG T GK+ + + T L+ F L ++ I A + + I
Sbjct: 219 ALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGH 278
Query: 467 TKDPS------RNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFR 520
DP R F + + +P LP ++ + +AK
Sbjct: 279 FNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPS 338
Query: 521 IPFAGKVEVCCFDKTGTLTSDSL------VVRGVAG---------------------LRD 553
+ G V C DKTGTLT++ + ++ V G L++
Sbjct: 339 VETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKN 398
Query: 554 GKEVTPVS-SIPVETHRALASCH-SLMQLDDG----TLVGDPLEKAMLTAVD-------- 599
K V P VE A C+ S + ++ VG+ E A+ T V+
Sbjct: 399 DKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTD 458
Query: 600 -WTLTKDEKVFP-RSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAP 657
+L+K E+ S+ Q +K F+ K MSV S K + VKGAP
Sbjct: 459 VRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAP 518
Query: 658 ETLHSMFSQCPPDYHHIHTE--------------------ISREGARVLALGYKELGHLT 697
E + +C +Y + T R+ R LAL ++
Sbjct: 519 E---GVIDRC--NYVRVGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKR 573
Query: 698 HQQAREVKREAL--ECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTAC 755
+ + L E L FVG + + P + + I+ ++A RV+MITGDN TA
Sbjct: 574 EEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAI 633
Query: 756 HVAQELHFIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDG 815
+ + + + + R R D LPLA + A A C
Sbjct: 634 AICRRIGIFGENEEV-------ADRAYTGREFDD---LPLAE---QREACRRACC----- 675
Query: 816 LAHLQATDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHA 875
FARV P K ++ L+ +T M GDG ND ALK A
Sbjct: 676 ---------------------FARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKA 714
Query: 876 DVGVAL 881
++G+A+
Sbjct: 715 EIGIAM 720
>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
sapiens]
Length = 946
Score = 83.6 bits (205), Expect = 1e-15
Identities = 144/649 (22%), Positives = 250/649 (38%), Gaps = 135/649 (20%)
Query: 271 SMLVAFEASLVQQQM--RNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIVPGDIVSIGRS 328
++LV + +Q+ +++ E+ KM P R K + + + E+VPGD+VS+
Sbjct: 140 AVLVVVTVAFIQEYRSEKSLEELTKM--VPPECNCLREGKLQHLLARELVPGDVVSLSIG 197
Query: 329 PQENLVPCDVLLLRGR-CIVDEAMLTGESVPQMKEPIEDLSPDRVLDLQADSRLHVIFGG 387
+ +P D+ L +VDE+ TGE+ P K + L +++F G
Sbjct: 198 DR---IPADIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGGDLTTLS-----NIVFMG 249
Query: 388 TKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLRTILFGVKRVTANNLETFIF 447
T +VQ+ Q G + + T + L +++ K++T F F
Sbjct: 250 T-LVQYGRGQGVVIGTGESSQFGEVFKMMQAEETPKTPLQKSMDRLGKQLTL-----FSF 303
Query: 448 ILFLLVFAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIA 507
+ L+ I W +G + +F + + +P LPI + + + ++
Sbjct: 304 GIIGLIMLIG-----WSQG-----KQLLSMFTIGVSLAVAAIPEGLPIVVMVTLVLGVLR 353
Query: 508 LAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVV--------------------RG 547
+AK + + + G V C DKTGTLT++ + V +G
Sbjct: 354 MAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVTSDGLRAEVSGVGYDGQG 413
Query: 548 VAGLRDGKEVTP-VSSIPVETHRALASCHSLMQLDDGTLVGDPLEKAMLTAVDWTLTKDE 606
L KEV S++ V + + ++G P E A++
Sbjct: 414 TVCLLPSKEVIKEFSNVSVGKLVEAGCVANNAVIRKNAVMGQPTEGALMALA-------M 466
Query: 607 KVFPRSIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPETLH---SM 663
K+ IK ++ + F+S K M+V S + D+ ++ KGA E + +M
Sbjct: 467 KMDLSDIKNSYIR-KKEIPFSSEQKWMAVKCSLKTEDQEDIYFM---KGALEEVIRYCTM 522
Query: 664 FSQ-------CPPDYHHIHTEISREGA---RVLALGY-KELGHLTHQQAREVKREALECS 712
++ P E R G+ RVLAL ELG LT
Sbjct: 523 YNNGGIPLPLTPQQRSFCLQEEKRMGSLGLRVLALASGPELGRLT--------------- 567
Query: 713 LKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLIL 772
F+G + + P + K ++ + + V MITGD TA + + +
Sbjct: 568 --FLGLVGIIDPPRVGVKEAVQVLSESGVSVKMITGDALETALAIGRNIG---------- 615
Query: 773 QPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQATDPQQLLRLIP 832
L G +A++ E + + + +L +
Sbjct: 616 ----------------------LCNGKLQAMSGE-----------EVDSVEKGELADRVG 642
Query: 833 HVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
V VF R +PK K +I +L+E G + M GDG ND ALK AD+G+A+
Sbjct: 643 KVSVFFRTSPKHKLKIIKALQESGAIVAMTGDGVNDAVALKSADIGIAM 691
>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
sapiens]
Length = 997
Score = 82.0 bits (201), Expect = 3e-15
Identities = 178/761 (23%), Positives = 291/761 (38%), Gaps = 162/761 (21%)
Query: 214 EIRAAEKKFGSNKA---------EMVVPDFSELFKE---RATAPFFVFQVFCVGLWCLDE 261
+++ ++++GSN+ E+V+ F +L A FV F G +
Sbjct: 28 QVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITA 87
Query: 262 YWYYSVFTLSMLVAFEASLVQQQMRNMSEIRKMGN-KPHMIQVYRS--RKWRPIASDEIV 318
+ V L +LVA V Q+ + I + +P M +VYR + + I + +IV
Sbjct: 88 FVEPFVILL-ILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIV 146
Query: 319 PGDIVSIGRSPQENLVPCDVLLLRGRCI---VDEAMLTGESVPQMKEPIEDLSPDRVLDL 375
PGDIV I + VP D+ L + VD+++LTGESV +K D V D
Sbjct: 147 PGDIVEIAVGDK---VPADIRLTSIKSTTLRVDQSILTGESVSVIKHT------DPVPDP 197
Query: 376 QA--DSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLRTILFG 433
+A + +++F GT + + V+ TG NT GK+ ++
Sbjct: 198 RAVNQDKKNMLFSGTNIAA---------------GKAMGVVVATGVNTEIGKIRDEMVAT 242
Query: 434 VKRVTA--NNLETFIFILFLLVFAIAAAAYVWIEGT-KDPS------RNRYKLFLECTLI 484
+ T L+ F L ++ I A ++ G DP R F +
Sbjct: 243 EQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVAL 302
Query: 485 LTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSL- 543
+ +P LP ++ + +AK + G V C DKTGTLT++ +
Sbjct: 303 AVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMS 362
Query: 544 ---------VVRGVAGLRD----GKEVTPVSSI-----PVETHR--ALASCHSLMQL-DD 582
V L + G P+ + PV H+ L ++ L +D
Sbjct: 363 VCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCND 422
Query: 583 GTL-----------VGDPLEKAMLTAVDWT---------LTKDEKVFP-RSIKTQGLKIH 621
L VG+ E A+ V+ L+K E+ S+ Q +K
Sbjct: 423 SALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKE 482
Query: 622 QRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPE------TLHSMFSQCPPDYHHIH 675
F+ K MSV + K T + + VKGAPE T + S P +
Sbjct: 483 FTLEFSRDRKSMSVYCTPNKPSRTSMSKM-FVKGAPEGVIDRCTHIRVGSTKVPMTSGVK 541
Query: 676 TEI---------SREGARVLALG------YKELGHLTHQQAREVKREALECSLKFVGFIV 720
+I + R LAL +E HL A +K E +L FVG +
Sbjct: 542 QKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHL-EDSANFIK---YETNLTFVGCVG 597
Query: 721 VSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLILQPPSEKGR 780
+ P + + + ++ + A RV+MITGDN TA + + + + + + + GR
Sbjct: 598 MLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSK--AFTGR 655
Query: 781 QCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQATDPQQLLRLIPHVQVFARV 840
+ + +P A + CL + + FARV
Sbjct: 656 EFD-------------ELNPSA---QRDACL---------------------NARCFARV 678
Query: 841 APKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
P K ++ L+ +T M GDG ND ALK A++G+A+
Sbjct: 679 EPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 719
>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1
[Homo sapiens]
Length = 1042
Score = 82.0 bits (201), Expect = 3e-15
Identities = 178/761 (23%), Positives = 291/761 (38%), Gaps = 162/761 (21%)
Query: 214 EIRAAEKKFGSNKA---------EMVVPDFSELFKE---RATAPFFVFQVFCVGLWCLDE 261
+++ ++++GSN+ E+V+ F +L A FV F G +
Sbjct: 28 QVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITA 87
Query: 262 YWYYSVFTLSMLVAFEASLVQQQMRNMSEIRKMGN-KPHMIQVYRS--RKWRPIASDEIV 318
+ V L +LVA V Q+ + I + +P M +VYR + + I + +IV
Sbjct: 88 FVEPFVILL-ILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIV 146
Query: 319 PGDIVSIGRSPQENLVPCDVLLLRGRCI---VDEAMLTGESVPQMKEPIEDLSPDRVLDL 375
PGDIV I + VP D+ L + VD+++LTGESV +K D V D
Sbjct: 147 PGDIVEIAVGDK---VPADIRLTSIKSTTLRVDQSILTGESVSVIKHT------DPVPDP 197
Query: 376 QA--DSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCVAYVLRTGFNTSQGKLLRTILFG 433
+A + +++F GT + + V+ TG NT GK+ ++
Sbjct: 198 RAVNQDKKNMLFSGTNIAA---------------GKAMGVVVATGVNTEIGKIRDEMVAT 242
Query: 434 VKRVTA--NNLETFIFILFLLVFAIAAAAYVWIEGT-KDPS------RNRYKLFLECTLI 484
+ T L+ F L ++ I A ++ G DP R F +
Sbjct: 243 EQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVAL 302
Query: 485 LTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSL- 543
+ +P LP ++ + +AK + G V C DKTGTLT++ +
Sbjct: 303 AVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMS 362
Query: 544 ---------VVRGVAGLRD----GKEVTPVSSI-----PVETHR--ALASCHSLMQL-DD 582
V L + G P+ + PV H+ L ++ L +D
Sbjct: 363 VCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCND 422
Query: 583 GTL-----------VGDPLEKAMLTAVDWT---------LTKDEKVFP-RSIKTQGLKIH 621
L VG+ E A+ V+ L+K E+ S+ Q +K
Sbjct: 423 SALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKE 482
Query: 622 QRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPE------TLHSMFSQCPPDYHHIH 675
F+ K MSV + K T + + VKGAPE T + S P +
Sbjct: 483 FTLEFSRDRKSMSVYCTPNKPSRTSMSKM-FVKGAPEGVIDRCTHIRVGSTKVPMTSGVK 541
Query: 676 TEI---------SREGARVLALG------YKELGHLTHQQAREVKREALECSLKFVGFIV 720
+I + R LAL +E HL A +K E +L FVG +
Sbjct: 542 QKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHL-EDSANFIK---YETNLTFVGCVG 597
Query: 721 VSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIEKAHTLILQPPSEKGR 780
+ P + + + ++ + A RV+MITGDN TA + + + + + + + GR
Sbjct: 598 MLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSK--AFTGR 655
Query: 781 QCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQATDPQQLLRLIPHVQVFARV 840
+ + +P A + CL + + FARV
Sbjct: 656 EFD-------------ELNPSA---QRDACL---------------------NARCFARV 678
Query: 841 APKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
P K ++ L+ +T M GDG ND ALK A++G+A+
Sbjct: 679 EPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 719
>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
sapiens]
Length = 1198
Score = 81.6 bits (200), Expect = 4e-15
Identities = 150/681 (22%), Positives = 262/681 (38%), Gaps = 113/681 (16%)
Query: 266 SVFTLSMLVAFEASLVQQQMRNMSEIRKMGNKPHMIQVYRSRKWRPIASDEIVPGDIVSI 325
SV + ++ AF ++Q R + + K V R+ + I EIV GDI +
Sbjct: 160 SVICVVLVTAFNDWSKEKQFRGLQSRIEQEQK---FTVVRAGQVVQIPVAEIVVGDIAQV 216
Query: 326 GRSPQENLVPCDVLLLRGRCI-VDEAMLTGESVPQMKEPIED---LSPDRVLD------- 374
+L+P D L ++G + +DE+ LTGES K +D LS V++
Sbjct: 217 KYG---DLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLV 273
Query: 375 --LQADSRLHVIF-----GGTKVVQHIPPQKATTG--------LKPVDSGCV-----AYV 414
+ +S+ +IF GG + + K G LK + G A +
Sbjct: 274 TAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDRKKASM 333
Query: 415 LRTGFNTSQGKLLR-TILFGVKRVTANNLETFIFILFLLVFAIAAAAYVWI-EGTKDPSR 472
+ + QGKL + + G + + + I +L+ V W+ E T +
Sbjct: 334 HKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQ 393
Query: 473 NRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFRIPFAGKVEVCCF 532
K F+ +L VP LP+ +++++ S+ + K G C
Sbjct: 394 YFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICS 453
Query: 533 DKTGTLTSDSL-VVRGVAGLRDGKEVTPVSSIPVETHRALASCHSLMQL---------DD 582
DKTGTLT++ + VV+ G KE+ SSI +T L + ++ +
Sbjct: 454 DKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKE 513
Query: 583 GTLVGDPLEKAMLTAVDWTLTKDEKVFPRSIKTQGLKIHQRFHFASALKRMSVLAS---- 638
G L K + + L + P + K+++ + F S K MS +
Sbjct: 514 GALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDE 573
Query: 639 ----YEKLGSTDL-----CYIAAVKGAPETLHSMFSQCPPDYHHIHTEISR----EGARV 685
Y K G++++ C I G P P D + ++ +G R
Sbjct: 574 SFRMYSK-GASEIVLKKCCKILNGAGEPRVFR------PRDRDEMVKKVIEPMACDGLRT 626
Query: 686 LALGYKELGHLTHQQAREVKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVM 745
+ + Y++ + + + + + L L + + + P++ + IR+ Q A V M
Sbjct: 627 ICVAYRDFPS-SPEPDWDNENDILN-ELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRM 684
Query: 746 ITGDNPLTACHVAQELHFIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALAL 805
+TGDN TA +A + I + E R+ R+ G I
Sbjct: 685 VTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRI--RNEKGEI-------------- 728
Query: 806 EYALCLTGDGLAHLQATDPQQLLRLIPHVQVFARVAPKQKEFVITSL-----KELGYVTL 860
+ +++ ++ P ++V AR +P K ++ + E V
Sbjct: 729 -----------------EQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVA 771
Query: 861 MCGDGTNDVGALKHADVGVAL 881
+ GDGTND ALK ADVG A+
Sbjct: 772 VTGDGTNDGPALKKADVGFAM 792
>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
sapiens]
Length = 999
Score = 81.3 bits (199), Expect = 5e-15
Identities = 153/660 (23%), Positives = 243/660 (36%), Gaps = 137/660 (20%)
Query: 297 KPHMIQVYRSRKW--RPIASDEIVPGDIVSIGRSPQENLVPCDVLLLRGRCI---VDEAM 351
+P M +V RS + + I + +IVPGDIV + + VP D+ L+ + VD+++
Sbjct: 123 EPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDK---VPADLRLIEIKSTTLRVDQSI 179
Query: 352 LTGESVPQMKEPIEDLSPDRVLDLQADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCV 411
LTGESV K E + R ++ + +++F GT + T+G V
Sbjct: 180 LTGESVSVTKHT-EAIPDPRAVN---QDKKNMLFSGTNI---------TSGK------AV 220
Query: 412 AYVLRTGFNTSQGKLLRTILFGV---KRVTANNLETFIFILFLLVFAIAAAAYVWIEGT- 467
+ TG +T GK+ R+ + V + L+ F L + I A +V G
Sbjct: 221 GVAVATGLHTELGKI-RSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHF 279
Query: 468 KDPS------RNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFRI 521
DP+ R F + + +P LP ++ + +A+ +
Sbjct: 280 ADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSV 339
Query: 522 PFAGKVEVCCFDKTGTLTSDSL-------VVRGVAG-------LRDGKEVTPVSSIP--- 564
G V C DKTGTLT++ + V AG G TP +
Sbjct: 340 ETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGD 399
Query: 565 -----------VETHRALASCH-SLMQLDDGTLVGDPLEKAMLTAVDWTLTK------DE 606
VE A C+ S + ++ V + + +A TA+ + K D
Sbjct: 400 QPVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDL 459
Query: 607 KVFPR--------SIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPE 658
+ R ++ Q ++ F+ K MSV + + T VKGAPE
Sbjct: 460 QALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPE 519
Query: 659 TLHSMFSQ----------CPPDYHHIHTEISREGA-----RVLALGYKELGHLTHQQARE 703
++ S P I +I G+ R LAL ++ +
Sbjct: 520 SVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELD 579
Query: 704 --VKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQEL 761
K E L FVG + + P + + A I A RVVMITGDN TA + + L
Sbjct: 580 DCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRL 639
Query: 762 HFIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQA 821
+ G+ R D
Sbjct: 640 GIFGDTEDV-------AGKAYTGREFDD-------------------------------- 660
Query: 822 TDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
P+Q + + FARV P K ++ +L+ +T M GDG ND ALK A++G+A+
Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720
>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 81.3 bits (199), Expect = 5e-15
Identities = 153/660 (23%), Positives = 243/660 (36%), Gaps = 137/660 (20%)
Query: 297 KPHMIQVYRSRKW--RPIASDEIVPGDIVSIGRSPQENLVPCDVLLLRGRCI---VDEAM 351
+P M +V RS + + I + +IVPGDIV + + VP D+ L+ + VD+++
Sbjct: 123 EPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDK---VPADLRLIEIKSTTLRVDQSI 179
Query: 352 LTGESVPQMKEPIEDLSPDRVLDLQADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCV 411
LTGESV K E + R ++ + +++F GT + T+G V
Sbjct: 180 LTGESVSVTKHT-EAIPDPRAVN---QDKKNMLFSGTNI---------TSGK------AV 220
Query: 412 AYVLRTGFNTSQGKLLRTILFGV---KRVTANNLETFIFILFLLVFAIAAAAYVWIEGT- 467
+ TG +T GK+ R+ + V + L+ F L + I A +V G
Sbjct: 221 GVAVATGLHTELGKI-RSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHF 279
Query: 468 KDPS------RNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFRI 521
DP+ R F + + +P LP ++ + +A+ +
Sbjct: 280 ADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSV 339
Query: 522 PFAGKVEVCCFDKTGTLTSDSL-------VVRGVAG-------LRDGKEVTPVSSIP--- 564
G V C DKTGTLT++ + V AG G TP +
Sbjct: 340 ETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGD 399
Query: 565 -----------VETHRALASCH-SLMQLDDGTLVGDPLEKAMLTAVDWTLTK------DE 606
VE A C+ S + ++ V + + +A TA+ + K D
Sbjct: 400 QPVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDL 459
Query: 607 KVFPR--------SIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPE 658
+ R ++ Q ++ F+ K MSV + + T VKGAPE
Sbjct: 460 QALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPE 519
Query: 659 TLHSMFSQ----------CPPDYHHIHTEISREGA-----RVLALGYKELGHLTHQQARE 703
++ S P I +I G+ R LAL ++ +
Sbjct: 520 SVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELD 579
Query: 704 --VKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQEL 761
K E L FVG + + P + + A I A RVVMITGDN TA + + L
Sbjct: 580 DCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRL 639
Query: 762 HFIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQA 821
+ G+ R D
Sbjct: 640 GIFGDTEDV-------AGKAYTGREFDD-------------------------------- 660
Query: 822 TDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
P+Q + + FARV P K ++ +L+ +T M GDG ND ALK A++G+A+
Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720
>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
sapiens]
Length = 998
Score = 81.3 bits (199), Expect = 5e-15
Identities = 153/660 (23%), Positives = 243/660 (36%), Gaps = 137/660 (20%)
Query: 297 KPHMIQVYRSRKW--RPIASDEIVPGDIVSIGRSPQENLVPCDVLLLRGRCI---VDEAM 351
+P M +V RS + + I + +IVPGDIV + + VP D+ L+ + VD+++
Sbjct: 123 EPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDK---VPADLRLIEIKSTTLRVDQSI 179
Query: 352 LTGESVPQMKEPIEDLSPDRVLDLQADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCV 411
LTGESV K E + R ++ + +++F GT + T+G V
Sbjct: 180 LTGESVSVTKHT-EAIPDPRAVN---QDKKNMLFSGTNI---------TSGK------AV 220
Query: 412 AYVLRTGFNTSQGKLLRTILFGV---KRVTANNLETFIFILFLLVFAIAAAAYVWIEGT- 467
+ TG +T GK+ R+ + V + L+ F L + I A +V G
Sbjct: 221 GVAVATGLHTELGKI-RSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHF 279
Query: 468 KDPS------RNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFRI 521
DP+ R F + + +P LP ++ + +A+ +
Sbjct: 280 ADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSV 339
Query: 522 PFAGKVEVCCFDKTGTLTSDSL-------VVRGVAG-------LRDGKEVTPVSSIP--- 564
G V C DKTGTLT++ + V AG G TP +
Sbjct: 340 ETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGD 399
Query: 565 -----------VETHRALASCH-SLMQLDDGTLVGDPLEKAMLTAVDWTLTK------DE 606
VE A C+ S + ++ V + + +A TA+ + K D
Sbjct: 400 QPVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDL 459
Query: 607 KVFPR--------SIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPE 658
+ R ++ Q ++ F+ K MSV + + T VKGAPE
Sbjct: 460 QALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPE 519
Query: 659 TLHSMFSQ----------CPPDYHHIHTEISREGA-----RVLALGYKELGHLTHQQARE 703
++ S P I +I G+ R LAL ++ +
Sbjct: 520 SVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELD 579
Query: 704 --VKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQEL 761
K E L FVG + + P + + A I A RVVMITGDN TA + + L
Sbjct: 580 DCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRL 639
Query: 762 HFIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQA 821
+ G+ R D
Sbjct: 640 GIFGDTEDV-------AGKAYTGREFDD-------------------------------- 660
Query: 822 TDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
P+Q + + FARV P K ++ +L+ +T M GDG ND ALK A++G+A+
Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720
>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 81.3 bits (199), Expect = 5e-15
Identities = 153/660 (23%), Positives = 243/660 (36%), Gaps = 137/660 (20%)
Query: 297 KPHMIQVYRSRKW--RPIASDEIVPGDIVSIGRSPQENLVPCDVLLLRGRCI---VDEAM 351
+P M +V RS + + I + +IVPGDIV + + VP D+ L+ + VD+++
Sbjct: 123 EPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDK---VPADLRLIEIKSTTLRVDQSI 179
Query: 352 LTGESVPQMKEPIEDLSPDRVLDLQADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCV 411
LTGESV K E + R ++ + +++F GT + T+G V
Sbjct: 180 LTGESVSVTKHT-EAIPDPRAVN---QDKKNMLFSGTNI---------TSGK------AV 220
Query: 412 AYVLRTGFNTSQGKLLRTILFGV---KRVTANNLETFIFILFLLVFAIAAAAYVWIEGT- 467
+ TG +T GK+ R+ + V + L+ F L + I A +V G
Sbjct: 221 GVAVATGLHTELGKI-RSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHF 279
Query: 468 KDPS------RNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFRI 521
DP+ R F + + +P LP ++ + +A+ +
Sbjct: 280 ADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSV 339
Query: 522 PFAGKVEVCCFDKTGTLTSDSL-------VVRGVAG-------LRDGKEVTPVSSIP--- 564
G V C DKTGTLT++ + V AG G TP +
Sbjct: 340 ETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGD 399
Query: 565 -----------VETHRALASCH-SLMQLDDGTLVGDPLEKAMLTAVDWTLTK------DE 606
VE A C+ S + ++ V + + +A TA+ + K D
Sbjct: 400 QPVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDL 459
Query: 607 KVFPR--------SIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPE 658
+ R ++ Q ++ F+ K MSV + + T VKGAPE
Sbjct: 460 QALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPE 519
Query: 659 TLHSMFSQ----------CPPDYHHIHTEISREGA-----RVLALGYKELGHLTHQQARE 703
++ S P I +I G+ R LAL ++ +
Sbjct: 520 SVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELD 579
Query: 704 --VKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQEL 761
K E L FVG + + P + + A I A RVVMITGDN TA + + L
Sbjct: 580 DCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRL 639
Query: 762 HFIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQA 821
+ G+ R D
Sbjct: 640 GIFGDTEDV-------AGKAYTGREFDD-------------------------------- 660
Query: 822 TDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
P+Q + + FARV P K ++ +L+ +T M GDG ND ALK A++G+A+
Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720
>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
sapiens]
Length = 1043
Score = 81.3 bits (199), Expect = 5e-15
Identities = 153/660 (23%), Positives = 243/660 (36%), Gaps = 137/660 (20%)
Query: 297 KPHMIQVYRSRKW--RPIASDEIVPGDIVSIGRSPQENLVPCDVLLLRGRCI---VDEAM 351
+P M +V RS + + I + +IVPGDIV + + VP D+ L+ + VD+++
Sbjct: 123 EPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDK---VPADLRLIEIKSTTLRVDQSI 179
Query: 352 LTGESVPQMKEPIEDLSPDRVLDLQADSRLHVIFGGTKVVQHIPPQKATTGLKPVDSGCV 411
LTGESV K E + R ++ + +++F GT + T+G V
Sbjct: 180 LTGESVSVTKHT-EAIPDPRAVN---QDKKNMLFSGTNI---------TSGK------AV 220
Query: 412 AYVLRTGFNTSQGKLLRTILFGV---KRVTANNLETFIFILFLLVFAIAAAAYVWIEGT- 467
+ TG +T GK+ R+ + V + L+ F L + I A +V G
Sbjct: 221 GVAVATGLHTELGKI-RSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHF 279
Query: 468 KDPS------RNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIALAKLYMYCTEPFRI 521
DP+ R F + + +P LP ++ + +A+ +
Sbjct: 280 ADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSV 339
Query: 522 PFAGKVEVCCFDKTGTLTSDSL-------VVRGVAG-------LRDGKEVTPVSSIP--- 564
G V C DKTGTLT++ + V AG G TP +
Sbjct: 340 ETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGD 399
Query: 565 -----------VETHRALASCH-SLMQLDDGTLVGDPLEKAMLTAVDWTLTK------DE 606
VE A C+ S + ++ V + + +A TA+ + K D
Sbjct: 400 QPVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDL 459
Query: 607 KVFPR--------SIKTQGLKIHQRFHFASALKRMSVLASYEKLGSTDLCYIAAVKGAPE 658
+ R ++ Q ++ F+ K MSV + + T VKGAPE
Sbjct: 460 QALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPE 519
Query: 659 TLHSMFSQ----------CPPDYHHIHTEISREGA-----RVLALGYKELGHLTHQQARE 703
++ S P I +I G+ R LAL ++ +
Sbjct: 520 SVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELD 579
Query: 704 --VKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQEL 761
K E L FVG + + P + + A I A RVVMITGDN TA + + L
Sbjct: 580 DCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRL 639
Query: 762 HFIEKAHTLILQPPSEKGRQCEWRSIDGSIVLPLARGSPKALALEYALCLTGDGLAHLQA 821
+ G+ R D
Sbjct: 640 GIFGDTEDV-------AGKAYTGREFDD-------------------------------- 660
Query: 822 TDPQQLLRLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVAL 881
P+Q + + FARV P K ++ +L+ +T M GDG ND ALK A++G+A+
Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,369,218
Number of Sequences: 37866
Number of extensions: 2045577
Number of successful extensions: 6100
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 5812
Number of HSP's gapped (non-prelim): 193
length of query: 1204
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1090
effective length of database: 13,930,794
effective search space: 15184565460
effective search space used: 15184565460
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.