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Search of human proteins with 170014684
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|170014684 IQ motif containing B1 isoform a [Homo sapiens]
(598 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|170014684 IQ motif containing B1 isoform a [Homo sapiens] 1170 0.0
gi|170014680 IQ motif containing B1 isoform c [Homo sapiens] 533 e-151
gi|126116596 asp (abnormal spindle)-like, microcephaly associate... 55 1e-07
gi|122937345 myosin VB [Homo sapiens] 50 6e-06
gi|154354979 myosin X [Homo sapiens] 48 3e-05
gi|156119615 myosin IXA [Homo sapiens] 47 4e-05
gi|122937512 myosin VIIB [Homo sapiens] 45 2e-04
gi|148746195 trichohyalin [Homo sapiens] 45 2e-04
gi|215982794 myosin VA isoform 2 [Homo sapiens] 44 4e-04
gi|215982791 myosin VA isoform 1 [Homo sapiens] 44 4e-04
gi|153945715 myosin VC [Homo sapiens] 44 6e-04
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 43 0.001
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 43 0.001
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 43 0.001
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 43 0.001
gi|21450705 leucine rich repeat containing 45 [Homo sapiens] 42 0.001
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 42 0.002
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 42 0.002
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 42 0.002
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 41 0.003
gi|45439327 periplakin [Homo sapiens] 41 0.004
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 40 0.005
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 40 0.005
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 40 0.005
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 40 0.005
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 40 0.005
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 39 0.010
gi|70980531 GGA binding partner [Homo sapiens] 39 0.014
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 38 0.023
gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens] 38 0.023
>gi|170014684 IQ motif containing B1 isoform a [Homo sapiens]
Length = 598
Score = 1170 bits (3028), Expect = 0.0
Identities = 598/598 (100%), Positives = 598/598 (100%)
Query: 1 MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ 60
MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ
Sbjct: 1 MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ 60
Query: 61 YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR 120
YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR
Sbjct: 61 YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR 120
Query: 121 QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI 180
QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI
Sbjct: 121 QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI 180
Query: 181 GSAVMMMLQNILQINSGDLLRIGRKALYSILDEVIFKLFSTPSPVIRSTATKLLLLMAES 240
GSAVMMMLQNILQINSGDLLRIGRKALYSILDEVIFKLFSTPSPVIRSTATKLLLLMAES
Sbjct: 181 GSAVMMMLQNILQINSGDLLRIGRKALYSILDEVIFKLFSTPSPVIRSTATKLLLLMAES 240
Query: 241 HQEILILLRQSTCYKGLRRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQKLHQAACL 300
HQEILILLRQSTCYKGLRRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQKLHQAACL
Sbjct: 241 HQEILILLRQSTCYKGLRRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQKLHQAACL 300
Query: 301 IQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAM 360
IQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAM
Sbjct: 301 IQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAM 360
Query: 361 RLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAA 420
RLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAA
Sbjct: 361 RLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAA 420
Query: 421 VTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSR 480
VTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSR
Sbjct: 421 VTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSR 480
Query: 481 ELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLS 540
ELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLS
Sbjct: 481 ELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLS 540
Query: 541 RSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESGDEIDVPKDELSIELENLFIGGTKPP 598
RSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESGDEIDVPKDELSIELENLFIGGTKPP
Sbjct: 541 RSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESGDEIDVPKDELSIELENLFIGGTKPP 598
>gi|170014680 IQ motif containing B1 isoform c [Homo sapiens]
Length = 465
Score = 533 bits (1373), Expect = e-151
Identities = 270/270 (100%), Positives = 270/270 (100%)
Query: 329 RSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEE 388
RSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEE
Sbjct: 196 RSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEE 255
Query: 389 KSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQ 448
KSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQ
Sbjct: 256 KSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQ 315
Query: 449 ELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHRE 508
ELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHRE
Sbjct: 316 ELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHRE 375
Query: 509 ALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKL 568
ALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKL
Sbjct: 376 ALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKL 435
Query: 569 GEESGDEIDVPKDELSIELENLFIGGTKPP 598
GEESGDEIDVPKDELSIELENLFIGGTKPP
Sbjct: 436 GEESGDEIDVPKDELSIELENLFIGGTKPP 465
Score = 401 bits (1030), Expect = e-111
Identities = 235/427 (55%), Positives = 285/427 (66%), Gaps = 61/427 (14%)
Query: 1 MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ 60
MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ
Sbjct: 1 MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ 60
Query: 61 YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR 120
YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR
Sbjct: 61 YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR 120
Query: 121 QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI 180
QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI
Sbjct: 121 QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI 180
Query: 181 GSAVMMMLQNILQINSGDLLRIGRKALYSILDEVIFKLFSTPSPVIRSTATKLLLLMAES 240
GSAVMMMLQNILQIN RS +K+LL +
Sbjct: 181 GSAVMMMLQNILQIN-------------------------------RSKRSKMLLEINRQ 209
Query: 241 HQEILILLRQSTCYKGLRRLLSKQETGTEFSQELR-QLVGLLSPMVYQEVEEQKLHQAAC 299
+E + L +L +++ S+EL+ ++ ++ P ++ + ++A
Sbjct: 210 KEEEDLKL----------QLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSAL 259
Query: 300 LIQAYWKGFQTRKRLKKLP------SAVIALQRS-----FRSKRSKMLLEINRQKEEEDL 348
+IQ +W+G++ RK + A + LQR+ + ++ K L R +E
Sbjct: 260 IIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTD 319
Query: 349 KLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFH 408
+++L+++ + R L M ++V RE+ ++ +Q ++ G +
Sbjct: 320 ARRVELKKRVDDYVRRHLGSPMSDVVS--------RELHAQAQERLQHYFMGRALEERAQ 371
Query: 409 QQRQSLI 415
Q R++LI
Sbjct: 372 QHREALI 378
>gi|126116596 asp (abnormal spindle)-like, microcephaly associated
[Homo sapiens]
Length = 3477
Score = 55.5 bits (132), Expect = 1e-07
Identities = 63/262 (24%), Positives = 116/262 (44%), Gaps = 39/262 (14%)
Query: 296 QAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQ 355
+AAC+IQ+YW+ Q R R L +I Q R + RQK ++ K + +Q
Sbjct: 1561 RAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQ-------QRQKYKKMKKAAVIIQ 1613
Query: 356 RQ-----RAMRLSRELQLSMLEIVHPGQVEKHYREMEEK--------SALIIQKHWRGYR 402
AM++ Q + ++ ++ YR M+ + S + IQ ++R Y
Sbjct: 1614 THFRAYIFAMKVLASYQKTRSAVI---VLQSAYRGMQARKMYIHILTSVIKIQSYYRAYV 1670
Query: 403 ERKNFHQQRQSLIEYKAAVTLQ---------RAALKFLAKCRKKKKLFAPWRGLQELTDA 453
+K F + + I+ ++ V ++ RAA F+ +C + KK+ A R +E
Sbjct: 1671 SKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKR--EEYMQM 1728
Query: 454 RR--VELKKRVDDY-VRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREAL 510
R ++L+ V Y VR+ + V+S + + + ++ Q+Y Q + A
Sbjct: 1729 RESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAY 1788
Query: 511 IAQIS--TNVEQLMKAPSLKEA 530
AQ++ N Q+ KA + +A
Sbjct: 1789 KAQVNQRKNFLQVKKAATCLQA 1810
Score = 50.8 bits (120), Expect = 3e-06
Identities = 39/140 (27%), Positives = 74/140 (52%), Gaps = 8/140 (5%)
Query: 294 LHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKR-SKMLLEINRQKEEEDLKLQL 352
L A +Q+ K QTRK+ L +A + +Q+ +RSK+ + E Q E +KLQ
Sbjct: 1678 LKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQA 1737
Query: 353 QLQR---QRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQ 409
++ ++ MRL R+ +S+ + ++Y +M K+ ++IQ ++ Y+ + N
Sbjct: 1738 FVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKM-YKAIIVIQNYYHAYKAQVN--- 1793
Query: 410 QRQSLIEYKAAVTLQRAALK 429
QR++ ++ K A T +AA +
Sbjct: 1794 QRKNFLQVKKAATCLQAAYR 1813
Score = 48.5 bits (114), Expect = 2e-05
Identities = 52/210 (24%), Positives = 102/210 (48%), Gaps = 29/210 (13%)
Query: 242 QEILILLRQSTCYKGLRRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQ--KLHQAAC 299
Q I+ + R YK L +T T F + ++ L S +V +Q + HQAA
Sbjct: 1849 QSIIKIQRWYRAYKTLH------DTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAAL 1902
Query: 300 LIQAYWKGFQTRKRLKKLPSAVIALQRSFRS-----KRSKMLLEINR-----QKEEEDLK 349
IQ+ ++ + +K+ + +A + +Q++FR+ K+ +E+ Q +
Sbjct: 1903 KIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKT 1962
Query: 350 LQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQ 409
L+ QLQRQ + +++ + V++ ++ +K+AL+IQK++R Y + +
Sbjct: 1963 LRRQLQRQHKCAI-------IIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGR---E 2012
Query: 410 QRQSLIEYKAAVTLQRAALKFLAKCRKKKK 439
Q ++ KAAV ++A + + K RK+ K
Sbjct: 2013 QNHLYLKTKAAVVTLQSAYRGM-KVRKRIK 2041
Score = 48.1 bits (113), Expect = 2e-05
Identities = 47/143 (32%), Positives = 70/143 (48%), Gaps = 27/143 (18%)
Query: 284 MVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQK 343
M+ +E E+ ++AA LIQ YW+ + TR+R KL I LQ R +M++ + K
Sbjct: 1337 MLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQ-----SRIRMIIAVTSYK 1391
Query: 344 EEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRE 403
L + +QR L R+ Q ++ Y EM + S LIIQ +R +++
Sbjct: 1392 RY--LWATVTIQRHWRAYLRRK------------QDQQRY-EMLKSSTLIIQSMFRKWKQ 1436
Query: 404 RKNFHQQRQSLIEYKAAVTLQRA 426
RK QS + KA V LQRA
Sbjct: 1437 RK-----MQS--QVKATVILQRA 1452
Score = 48.1 bits (113), Expect = 2e-05
Identities = 47/180 (26%), Positives = 84/180 (46%), Gaps = 14/180 (7%)
Query: 287 QEVEEQKLHQAACL-IQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKM-LLEINR--- 341
Q+ EE + +C+ +QA+ +G+ RK+++ AVI+LQ FR ++++ L++ +
Sbjct: 1720 QKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAII 1779
Query: 342 --QKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWR 399
Q K Q+ QR L + + L+ + G + + + +AL IQ +R
Sbjct: 1780 VIQNYYHAYKAQV---NQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFR 1836
Query: 400 GYRERKNFHQQRQSLIE----YKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARR 455
GY +R + QS+I+ Y+A TL FL L + +RG + RR
Sbjct: 1837 GYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRR 1896
Score = 47.0 bits (110), Expect = 5e-05
Identities = 53/250 (21%), Positives = 115/250 (46%), Gaps = 45/250 (18%)
Query: 240 SHQEILILLRQSTCYKGL-------RRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQ 292
+H+E L +L+ +G R L+ + + ++ R + L + + ++
Sbjct: 2970 AHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAI--LPAKIAHEHFLMI 3027
Query: 293 KLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSK---RSKMLLEINRQKEEEDLK 349
K H+AACLIQA+++G++ R+ + SA + +Q+ R++ + + + I +K L+
Sbjct: 3028 KRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQ 3087
Query: 350 LQLQLQRQRAMRLSRELQLSMLEI-------VHPGQVEKHYR--------EMEEKSALII 394
++ R L + ++ +L ++ ++++ Y+ + S + I
Sbjct: 3088 ALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVICI 3147
Query: 395 QKHWRGYRERKNFHQQRQSL--IEY----------KAAVTLQRAALKFLAKCRKKK---- 438
Q+ +R + K F Q+ S+ IE+ +AA +Q+A FL + +++K
Sbjct: 3148 QRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSG 3207
Query: 439 --KLFAPWRG 446
K+ A WRG
Sbjct: 3208 IIKIQALWRG 3217
Score = 45.1 bits (105), Expect = 2e-04
Identities = 45/243 (18%), Positives = 111/243 (45%), Gaps = 14/243 (5%)
Query: 212 DEVIFKLFSTPSPVIRSTATKLLLLMAESHQEILILLRQSTCYKGLRRLLSKQETGTEFS 271
D+ +++ + + +I+S K +S + ++L+++ LR+ +K+E
Sbjct: 1413 DQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQ-AKEENSAIII 1471
Query: 272 QELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSK 331
Q ++ L +Y + +IQ ++ FQ +K K+ +++ +Q+ +++
Sbjct: 1472 QSWYRMHKELRKYIY-------IRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAY 1524
Query: 332 RSKMLLEIN-RQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKS 390
+ N QK ++LQ +R +A L R+++ + + + + R + K
Sbjct: 1525 LKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKK 1584
Query: 391 ALI-IQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKK----LFAPWR 445
+I Q H R +++R+ + + +++ + + A+K LA +K + L + +R
Sbjct: 1585 TIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYR 1644
Query: 446 GLQ 448
G+Q
Sbjct: 1645 GMQ 1647
Score = 44.7 bits (104), Expect = 2e-04
Identities = 45/232 (19%), Positives = 111/232 (47%), Gaps = 14/232 (6%)
Query: 292 QKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRS---KRSKMLLEINRQKEEEDL 348
+ +H +A LIQ+ ++ R+R L A I +QR +R+ + K+ ++ +K +
Sbjct: 2405 KSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAA--I 2462
Query: 349 KLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREME--EKSALIIQKHWRGYR---- 402
+Q +R + +E+Q + + I ++ + Y + + ++++IQ+H+R YR
Sbjct: 2463 TIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKL 2522
Query: 403 ERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRV 462
+R+N+ +Q S + +AA +A K + + + +R ++ ++++ ++
Sbjct: 2523 QRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATKI 2582
Query: 463 DDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQ-QHREALIAQ 513
++ + V + + + +Q F ++++ Q QH+ A+I Q
Sbjct: 2583 --IQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQ 2632
Score = 44.3 bits (103), Expect = 3e-04
Identities = 57/272 (20%), Positives = 120/272 (44%), Gaps = 32/272 (11%)
Query: 269 EFSQELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSF 328
E +E G + ++++EQ HQAA +IQ + K F+ RK L + V+++QR +
Sbjct: 2601 ELKKETCVQAGFQDMNIKKQIQEQ--HQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRY 2658
Query: 329 R---SKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQ------V 379
R + R++ ++ I ++ +Q + A + ++ ++ + + +
Sbjct: 2659 RKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVI 2718
Query: 380 EKHYR-----EMEEKSALIIQKH-------WRGYRER---KNFHQQRQSLIEYKAAVTLQ 424
+ +YR + E K+ L +QK +RG + R KN +++ + I ++A+
Sbjct: 2719 QNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMAAIVNQSALCCY 2778
Query: 425 RAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHA 484
R+ ++ A + + + W L ++ E + V + +V+R+L
Sbjct: 2779 RSKTQYEA-VQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVT--IQKAFCRMVTRKLET 2835
Query: 485 QAQERLQ-HYFMGRALEER--AQQHREALIAQ 513
Q L+ +F+ A+ R QQ R A+ Q
Sbjct: 2836 QKCAALRIQFFLQMAVYRRRFVQQKRAAITLQ 2867
Score = 42.4 bits (98), Expect = 0.001
Identities = 45/198 (22%), Positives = 87/198 (43%), Gaps = 39/198 (19%)
Query: 258 RRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKL 317
RR LS ++T ++ R + + + +V+ A IQ+ ++ + RKR++++
Sbjct: 2280 RRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQN-----AVIKIQSSYRRWMIRKRMREM 2334
Query: 318 PSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPG 377
A +Q +FR R M + +Q + +Q Q Q RA +L R+
Sbjct: 2335 HRAATFIQSTFRMHRLHMRYQALKQAS---VVIQQQYQANRAAKLQRQ------------ 2379
Query: 378 QVEKHYREMEEKSALIIQKHWRGYRERKNFHQQR----------QSLIEYKAAVTLQRAA 427
HY + SA+I+Q +RG + R++ +SL+ + ++L++A
Sbjct: 2380 ----HYLR-QRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKAT 2434
Query: 428 L----KFLAKCRKKKKLF 441
+ K+ A K KL+
Sbjct: 2435 IFVQRKYRATICAKHKLY 2452
Score = 38.9 bits (89), Expect = 0.014
Identities = 49/241 (20%), Positives = 101/241 (41%), Gaps = 35/241 (14%)
Query: 273 ELRQLVGLLSPMVYQEV---EEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFR 329
ELR V +L M + + Q+ H+ A +IQ+Y++ +K+ K + A + +Q+ +R
Sbjct: 1946 ELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYR 2005
Query: 330 SKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPG-QVEKHYREMEE 388
+ I R+ Q + L + + L+ + G +V K ++
Sbjct: 2006 A------YSIGRE--------------QNHLYLKTKAAVVTLQSAYRGMKVRKRIKDC-N 2044
Query: 389 KSALIIQKHWRGYRERKNFHQQRQSLI----EYKAAVTLQRAALKFLAKCRKKKKLFAPW 444
K+A+ IQ +R Y+ +K + R S I Y+ ++L + K+ + +
Sbjct: 2045 KAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVY 2104
Query: 445 RGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQA---QERLQHYFMGRALEE 501
RG++ R ++ R +++ S + + A Q R + Y+ G+ E
Sbjct: 2105 RGIRV---RRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQRE 2161
Query: 502 R 502
+
Sbjct: 2162 K 2162
Score = 38.9 bits (89), Expect = 0.014
Identities = 44/162 (27%), Positives = 73/162 (45%), Gaps = 23/162 (14%)
Query: 284 MVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQK 343
MV +++E QK AA IQ + + R+R + A I LQ FR+ +++
Sbjct: 2828 MVTRKLETQKC--AALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRK-------- 2877
Query: 344 EEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRE 403
Q L R+ A+ L + + L H QV R S +IIQ +G+ +
Sbjct: 2878 -------QFLLYRKAAVVLQNHYR-AFLSAKHQRQVYLQIRS----SVIIIQARSKGFIQ 2925
Query: 404 RKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWR 445
++ F + + S I+ +A RA K+L K + K+ A +R
Sbjct: 2926 KRKFQEIKNSTIKIQAMWRRYRAK-KYLCKVKAACKIQAWYR 2966
Score = 38.5 bits (88), Expect = 0.018
Identities = 31/137 (22%), Positives = 66/137 (48%), Gaps = 17/137 (12%)
Query: 296 QAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRS-------KMLLEINRQKEEEDL 348
+A ++QA ++G + R+ L+K+ +A +Q ++R R K + + +Q+
Sbjct: 2168 KAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMK 2227
Query: 349 KLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFH 408
+ +Q QR +R S + ++ + G+ + + +M +A +IQ+ +R R+ F
Sbjct: 2228 ERNIQFQRYNKLRHS----VIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRF- 2282
Query: 409 QQRQSLIEYKAAVTLQR 425
L K A+ +QR
Sbjct: 2283 -----LSLKKTAILIQR 2294
Score = 37.7 bits (86), Expect = 0.030
Identities = 54/264 (20%), Positives = 116/264 (43%), Gaps = 26/264 (9%)
Query: 256 GLRRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLK 315
G+ +++ + E + ++ LS + + ++ +K +AA LIQ W+ ++ + LK
Sbjct: 1229 GIPAMINHSDMSNTIPDE-KVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKTDLK 1287
Query: 316 KLPSAVIALQRSFRSKRSKMLLEIN---RQKEEEDLKLQLQLQRQRAMRLSRELQLSMLE 372
+ Q ++ R L IN +Q+ + + L +Q+ R+ + +L ML+
Sbjct: 1288 R-------HQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKY-WRRVLAQRKLLMLK 1339
Query: 373 IVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLA 432
++ +++ K+A +IQ +WR Y R+ F + + I ++ + + A +
Sbjct: 1340 -------KEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKR 1392
Query: 433 KCRKKKKLFAPWRG-LQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQER-- 489
+ WR L+ D +R E+ K ++ S R++ +Q +
Sbjct: 1393 YLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQ----SMFRKWKQRKMQSQVKATVI 1448
Query: 490 LQHYFMGRALEERAQQHREALIAQ 513
LQ F L ++A++ A+I Q
Sbjct: 1449 LQRAFREWHLRKQAKEENSAIIIQ 1472
Score = 37.0 bits (84), Expect = 0.052
Identities = 34/145 (23%), Positives = 62/145 (42%), Gaps = 18/145 (12%)
Query: 293 KLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQL 352
KL + IQA ++G + R+ LK + A +QR FR+ + R++ K +
Sbjct: 2238 KLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTL-------MMRRRFLSLKKTAI 2290
Query: 353 QLQRQRAMRLSRELQLSMLEIVHP----------GQVEKHYREMEEKSALIIQKHWRGYR 402
+QR+ L + L L++ + + K REM ++A IQ +R +R
Sbjct: 2291 LIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREM-HRAATFIQSTFRMHR 2349
Query: 403 ERKNFHQQRQSLIEYKAAVTLQRAA 427
+ +Q+ + + RAA
Sbjct: 2350 LHMRYQALKQASVVIQQQYQANRAA 2374
Score = 36.6 bits (83), Expect = 0.068
Identities = 31/134 (23%), Positives = 65/134 (48%), Gaps = 6/134 (4%)
Query: 293 KLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQL 352
++ + +IQA KGF +++ +++ ++ I +Q +R R+K L K + K+Q
Sbjct: 2908 QIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYL----CKVKAACKIQA 2963
Query: 353 QLQRQRAMR--LSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQ 410
+ RA + L+ + +++ ++E+ SA+IIQ+ WR K H+
Sbjct: 2964 WYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEH 3023
Query: 411 RQSLIEYKAAVTLQ 424
+ ++AA +Q
Sbjct: 3024 FLMIKRHRAACLIQ 3037
Score = 30.0 bits (66), Expect = 6.3
Identities = 72/342 (21%), Positives = 132/342 (38%), Gaps = 65/342 (19%)
Query: 241 HQEILIL----LRQSTCYKGLR--RLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQKL 294
H+E L L ++ + Y+G+R R + F + + M + +
Sbjct: 2087 HKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATF-------IKAMFKMHQSRISYHTM 2139
Query: 295 HQAACLIQ----AYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKL 350
+AA +IQ AY++G R++ + AV LQ SFR R + L R+ + +
Sbjct: 2140 RKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTL---RKMQTAATLI 2196
Query: 351 QLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEK------------SALIIQKHW 398
Q +R R +L+ V++ Y M+E+ S + IQ +
Sbjct: 2197 QSNYRRYRQQTYFNKLKKI------TKTVQQRYWAMKERNIQFQRYNKLRHSVIYIQAIF 2250
Query: 399 RGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVEL 458
RG + R++ + AA +Q R+ + L R L A ++
Sbjct: 2251 RGKKARRHLKMM------HIAATLIQ----------RRFRTLMMRRRFLSLKKTAILIQR 2294
Query: 459 KKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNV 518
K R + HL V + + Q+ R + + + + E HR A Q + +
Sbjct: 2295 KYRAHLCTKHHL--QFLQVQNAVIKIQSSYR--RWMIRKRMRE---MHRAATFIQSTFRM 2347
Query: 519 EQL-MKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHLTTLKH 559
+L M+ +LK+A + + + AAK ++ H +H
Sbjct: 2348 HRLHMRYQALKQASVVIQQQYQANR---AAKLQRQHYLRQRH 2386
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 50.1 bits (118), Expect = 6e-06
Identities = 58/243 (23%), Positives = 106/243 (43%), Gaps = 22/243 (9%)
Query: 287 QEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLE-INRQKEE 345
+++ K A +IQ +G+ + + +L A + LQR R ++ L E + R +
Sbjct: 757 EKLRADKFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAA 816
Query: 346 EDLKLQLQLQRQR-AMRLSRELQLSMLEIVHPGQVEKHYRE-MEEKSALIIQKHWRGYRE 403
L+ ++QR R A + R + + V + YR+ + E A IQKH RG+
Sbjct: 817 VVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMA 876
Query: 404 RKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQEL------TDARRVE 457
R++F + R AA+ +Q A + L R+ K L R + L + + V+
Sbjct: 877 RRHFQRLRD------AAIVIQ-CAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQ 929
Query: 458 LKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQ----HYFM--GRALEERAQQHREALI 511
L++++D+ + V+ + ERL+ HY G R Q+ E+L
Sbjct: 930 LQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLR 989
Query: 512 AQI 514
++
Sbjct: 990 TEL 992
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 47.8 bits (112), Expect = 3e-05
Identities = 57/263 (21%), Positives = 123/263 (46%), Gaps = 21/263 (7%)
Query: 213 EVIFKLFSTPSPVIRSTATKLLLLMAESHQE-----ILILLRQSTCYKGLRRLLSKQETG 267
+V+ + + P V R T LL L S+ E + LR+S K +R ++E
Sbjct: 687 KVLMRNLALPEDV-RGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKR---REEEV 742
Query: 268 TEFSQELR-QLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQR 326
+ + +R ++G L+ Y+ K+ +IQ ++ F R+R L A I Q+
Sbjct: 743 SHAAMVIRAHVLGFLARKQYR-----KVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQK 797
Query: 327 SFRSKRSKMLLE--INRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYR 384
R + ++ + + ++E+E+ K Q + ++++ RE + E Q E+ R
Sbjct: 798 QLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETR 857
Query: 385 EMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPW 444
+ +E AL QK + + +Q+++ + + + L++ ++ L + +++++L
Sbjct: 858 KQQELEAL--QKSQKEAELTRELEKQKENK-QVEEILRLEK-EIEDLQRMKEQQELSLTE 913
Query: 445 RGLQELTDARRVELKKRVDDYVR 467
LQ+L + R EL++ ++ R
Sbjct: 914 ASLQKLQERRDQELRRLEEEACR 936
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 47.4 bits (111), Expect = 4e-05
Identities = 41/177 (23%), Positives = 80/177 (45%), Gaps = 5/177 (2%)
Query: 287 QEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSK-RSKMLLEINRQKEE 345
Q++ Q++ + L+Q +++ R+ L A + +QR +R+ K + + QK+
Sbjct: 1012 QDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDA 1071
Query: 346 ---EDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYR 402
LQ + + R L+L IV + +YR +A+ IQ W+ YR
Sbjct: 1072 FVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRR-RHMAAICIQARWKAYR 1130
Query: 403 ERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELK 459
E K + +QR+ +I ++ RA +F A ++ + P GL + +E++
Sbjct: 1131 ESKRYQEQRKKIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLEIQ 1187
>gi|122937512 myosin VIIB [Homo sapiens]
Length = 2116
Score = 45.1 bits (105), Expect = 2e-04
Identities = 33/123 (26%), Positives = 64/123 (52%), Gaps = 7/123 (5%)
Query: 292 QKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQ---RSFRSKRSKMLLEINRQKEEEDL 348
Q L +AA IQ +G++ RK + A + LQ R + ++R+ L+ + ++ +
Sbjct: 761 QVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIA 820
Query: 349 KLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFH 408
+ Q ++ +AMR R +QL L G + + + + ++ ++IQ H RG R+NF
Sbjct: 821 RSQPLARQYQAMR-QRTVQLQAL---CRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQ 876
Query: 409 QQR 411
Q++
Sbjct: 877 QRK 879
Score = 35.4 bits (80), Expect = 0.15
Identities = 45/219 (20%), Positives = 92/219 (42%), Gaps = 33/219 (15%)
Query: 254 YKGLRRLLSKQETGTEFS---QELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQT 310
Y G+ + +++G +E Q G+L P + + KL Q I W
Sbjct: 677 YSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVW----- 731
Query: 311 RKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSM 370
+ + +++ ++K+ L ++ +D L++Q R+ L R LS+
Sbjct: 732 -----------LRTDKDWKAGKTKIFL-----RDHQDTLLEVQ----RSQVLDRAA-LSI 770
Query: 371 LEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKF 430
+++ + K + + ++A+ +Q WRGY R+NF +A Q A ++
Sbjct: 771 QKVLRGYRYRKEFLR-QRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQY 829
Query: 431 LAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRH 469
A ++ +L A RG ++V+ K+R ++ H
Sbjct: 830 QAMRQRTVQLQALCRG---YLVRQQVQAKRRAVVVIQAH 865
Score = 35.0 bits (79), Expect = 0.20
Identities = 40/171 (23%), Positives = 72/171 (42%), Gaps = 19/171 (11%)
Query: 267 GTEFSQELRQLVGLLS---PMVYQEVEEQK------LHQAACLIQAYWKGFQTRKRLKKL 317
G++F Q L QL+ +L+ P + ++ + + CL Q + G ++K
Sbjct: 630 GSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKS 689
Query: 318 PSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIV--- 374
+ F + +L R + + L+ +R ++ + +I
Sbjct: 690 GFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRD 749
Query: 375 -HPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQ 424
+E ++ +++AL IQK RGYR RK F +QR +AAVTLQ
Sbjct: 750 HQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQR------RAAVTLQ 794
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 44.7 bits (104), Expect = 2e-04
Identities = 51/250 (20%), Positives = 103/250 (41%), Gaps = 22/250 (8%)
Query: 324 LQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHY 383
L+R + +R + L + + E+ L+ + QL+R++ +R ++L+ E H + E+
Sbjct: 383 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQER 442
Query: 384 REMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAA--LKFLAKCRKKKKLF 441
RE K ++ W E H+Q + + K +R LK + R++++
Sbjct: 443 REQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQER 502
Query: 442 APWRGLQELTDARRVELKK-----------RVDDYVRRHLGSPMSDVVSRELHAQAQERL 490
+ +E + R LK+ R + +RR ++ RE + ++
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Query: 491 QHYFMGRALEERAQQ--------HREALIAQISTNVEQLMKAPSLKEAEGKE-PELFLSR 541
+ + R EER Q ++ L + +EQ +K ++ E +E E L R
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKR 622
Query: 542 SRPVAAKAKQ 551
P + +Q
Sbjct: 623 EEPEEERRQQ 632
Score = 41.6 bits (96), Expect = 0.002
Identities = 69/285 (24%), Positives = 119/285 (41%), Gaps = 36/285 (12%)
Query: 261 LSKQETGTEFSQELRQLVGLLSPMVYQ-EVEEQKLHQAACLIQAYWKGFQTRKRLKKLPS 319
L ++E G + QE R+ ++ ++EE++ + L Q RK + L
Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
Query: 320 AVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQV 379
LQR R KR + E RQ EE+ QLQ + ++ +R RE + +
Sbjct: 909 EEEELQREEREKRRRQ--EQERQYREEE---QLQQEEEQLLREEREKRRRQ-------ER 956
Query: 380 EKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKK 439
E+ YR ++K ++ G K Q+R+ +Y+ LQ+ + L + R+K++
Sbjct: 957 ERQYR--KDKKLQQKEEQLLGEEPEKRRRQEREK--KYREEEELQQEEEQLLREEREKRR 1012
Query: 440 LFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRAL 499
R E ++ EL++ + +R RE + QER + Y R
Sbjct: 1013 -----RQEWERQYRKKDELQQEEEQLLRE----------ERE-KRRLQERERQY---REE 1053
Query: 500 EERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRP 544
EE Q+ + L + T Q ++ KE E ++ E L R P
Sbjct: 1054 EELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098
Score = 37.4 bits (85), Expect = 0.040
Identities = 52/247 (21%), Positives = 103/247 (41%), Gaps = 12/247 (4%)
Query: 311 RKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSM 370
R+R K+ + +S++ + L + +RQ+ +E+L Q Q ++R R + E QL
Sbjct: 136 RRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQS 195
Query: 371 LEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKF 430
+ + E+ E + + +++ +G E++ ++RQ + + R
Sbjct: 196 CK---GHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETV 252
Query: 431 LAKCRKKKKLFAP--WRGLQE----LTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHA 484
L K +K + P R LQE L R EL++ + ++ + R+
Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK--- 309
Query: 485 QAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRP 544
Q +ER + R +ER +Q E Q+ E+ + +E E + E L R +
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369
Query: 545 VAAKAKQ 551
+ +Q
Sbjct: 370 EERREQQ 376
Score = 34.7 bits (78), Expect = 0.26
Identities = 41/189 (21%), Positives = 84/189 (44%), Gaps = 17/189 (8%)
Query: 236 LMAESHQEILILLRQSTCYKGLRRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEE--QK 293
L+ E ++ L + ++ + L +QE +F QE +QL ++E E+ Q+
Sbjct: 1675 LLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQE 1734
Query: 294 LHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQ-- 351
Q Q ++ ++L+ L+R R ++ + ++ +++EE+ L+ Q
Sbjct: 1735 TEQEQLRRQERYRKILEEEQLRPEREEQ-QLRRQERDRKFREEEQLRQEREEQQLRSQES 1793
Query: 352 -LQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYR------EMEEKSALIIQKHWRGYRER 404
+ + + +R RE Q + P Q + YR ++EE+ + Q+ R YR
Sbjct: 1794 DRKFREEEQLRQEREEQQ-----LRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAE 1848
Query: 405 KNFHQQRQS 413
+ F Q +S
Sbjct: 1849 EQFATQEKS 1857
Score = 32.0 bits (71), Expect = 1.7
Identities = 40/235 (17%), Positives = 100/235 (42%), Gaps = 23/235 (9%)
Query: 287 QEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEE 346
++ EE++L Q Q Q R+ ++ ++ + R ++ + + R++EE
Sbjct: 521 RQEEEERLQQRLRSEQ------QLRREQEERREQLLKREEEKRLEQERREQRLKREQEER 574
Query: 347 DLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYRE------------MEEKSALII 394
+L + + +R RL RE + + + + +VE+ +E EE+ ++
Sbjct: 575 RDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLL 634
Query: 395 QKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDAR 454
+ + R ++ +++Q E + + L+ ++ K+ R QEL +
Sbjct: 635 KSEEQEERRQQQLRREQQERREQRLKREEEEERLE-----QRLKREHEEERREQELAEEE 689
Query: 455 RVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREA 509
+ + ++R+ + + S+ +R+ ++ R Q R +E ++ RE+
Sbjct: 690 QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES 744
Score = 30.8 bits (68), Expect = 3.7
Identities = 55/246 (22%), Positives = 100/246 (40%), Gaps = 45/246 (18%)
Query: 324 LQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHP------- 376
L+R +R K ++ E + EE K + Q +R+R R ELQ +++
Sbjct: 1076 LERQYR-KEEELQQEEEQLLREEPEKRRRQ-ERERQCREEEELQQEEEQLLREEREKRRR 1133
Query: 377 GQVEKHYREME----EKSALI--------IQKHWRGYRERKNFHQQRQSLI--------- 415
++E+ YRE E E+ L+ Q+ R YRE + Q+ + L+
Sbjct: 1134 QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ 1193
Query: 416 ----EYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDA---RRVELKKRVDDYVRR 468
+Y+ LQR K + + ++ W+ E +A +V K R ++ R+
Sbjct: 1194 ERERQYREEEELQRQKRKQRYR-DEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252
Query: 469 HLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLK 528
S + D Q+Q+ LQH + +R Q+ R E+ ++ K
Sbjct: 1253 LEDSQLRD-------RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQK 1305
Query: 529 EAEGKE 534
EA+ ++
Sbjct: 1306 EAKRRD 1311
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 43.9 bits (102), Expect = 4e-04
Identities = 43/219 (19%), Positives = 99/219 (45%), Gaps = 6/219 (2%)
Query: 249 RQSTCYKGLRRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGF 308
R+ TC L +L+ ++ ++ G ++ + +++ KL A IQ +G+
Sbjct: 723 RKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYL--EKLRADKLRAACIRIQKTIRGW 780
Query: 309 QTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDL--KLQLQLQRQRAMRLSREL 366
RK+ ++ A I +QR R +++ + R+ + + K +R ++ R
Sbjct: 781 LLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAA 840
Query: 367 QLSMLEIVHPGQVEKHYRE-MEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQR 425
+ + + YR+ + E A+IIQK RG+ R ++ + ++I Y +
Sbjct: 841 TIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAII-YLQCCFRRM 899
Query: 426 AALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDD 464
A + L K + + + ++ L + + ++L+++VD+
Sbjct: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDE 938
Score = 32.0 bits (71), Expect = 1.7
Identities = 63/274 (22%), Positives = 111/274 (40%), Gaps = 40/274 (14%)
Query: 296 QAACLIQAYWKGFQTRKRLKKLPSAVIALQ---RSF--RSKRSKMLLE---INRQKEEED 347
+AA +IQ YW+ + R+R K +A I LQ R F R++ K+L E + QK
Sbjct: 816 KAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRG 875
Query: 348 LKLQLQLQRQ-----------RAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQK 396
+ +R R M REL+ +E + +K + ME K I+Q
Sbjct: 876 WLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENK---IMQL 932
Query: 397 HWRGYRERKNFHQQRQSLIE----YKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTD 452
+ + K++ + L Y + R+ L+ L ++ K +
Sbjct: 933 QRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAK----------VAT 982
Query: 453 ARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERA--QQHREAL 510
R + L++ + +R+ L S+ E HA ++ + EE +Q +EAL
Sbjct: 983 GRVLSLQEEIAK-LRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEAL 1041
Query: 511 IAQISTNVEQLMKAPSLK-EAEGKEPELFLSRSR 543
+I +++ + K E K+ EL L+ R
Sbjct: 1042 NHRIVQQAKEMTETMEKKLVEETKQLELDLNDER 1075
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 43.9 bits (102), Expect = 4e-04
Identities = 43/219 (19%), Positives = 99/219 (45%), Gaps = 6/219 (2%)
Query: 249 RQSTCYKGLRRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGF 308
R+ TC L +L+ ++ ++ G ++ + +++ KL A IQ +G+
Sbjct: 723 RKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYL--EKLRADKLRAACIRIQKTIRGW 780
Query: 309 QTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDL--KLQLQLQRQRAMRLSREL 366
RK+ ++ A I +QR R +++ + R+ + + K +R ++ R
Sbjct: 781 LLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAA 840
Query: 367 QLSMLEIVHPGQVEKHYRE-MEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQR 425
+ + + YR+ + E A+IIQK RG+ R ++ + ++I Y +
Sbjct: 841 TIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAII-YLQCCFRRM 899
Query: 426 AALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDD 464
A + L K + + + ++ L + + ++L+++VD+
Sbjct: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDE 938
Score = 32.0 bits (71), Expect = 1.7
Identities = 63/274 (22%), Positives = 111/274 (40%), Gaps = 40/274 (14%)
Query: 296 QAACLIQAYWKGFQTRKRLKKLPSAVIALQ---RSF--RSKRSKMLLE---INRQKEEED 347
+AA +IQ YW+ + R+R K +A I LQ R F R++ K+L E + QK
Sbjct: 816 KAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRG 875
Query: 348 LKLQLQLQRQ-----------RAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQK 396
+ +R R M REL+ +E + +K + ME K I+Q
Sbjct: 876 WLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENK---IMQL 932
Query: 397 HWRGYRERKNFHQQRQSLIE----YKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTD 452
+ + K++ + L Y + R+ L+ L ++ K +
Sbjct: 933 QRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAK----------VAT 982
Query: 453 ARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERA--QQHREAL 510
R + L++ + +R+ L S+ E HA ++ + EE +Q +EAL
Sbjct: 983 GRVLSLQEEIAK-LRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEAL 1041
Query: 511 IAQISTNVEQLMKAPSLK-EAEGKEPELFLSRSR 543
+I +++ + K E K+ EL L+ R
Sbjct: 1042 NHRIVQQAKEMTETMEKKLVEETKQLELDLNDER 1075
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 43.5 bits (101), Expect = 6e-04
Identities = 55/275 (20%), Positives = 121/275 (44%), Gaps = 35/275 (12%)
Query: 287 QEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRS--KMLLEINRQKE 344
+++ KL Q+ ++Q + +G+ RK+ + A + +Q+ FR +++ K + + ++
Sbjct: 749 EKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEA 808
Query: 345 EEDLKLQLQLQR---QRAMRLSRELQLSMLEIVHPGQVEKHYREM-EEKSALIIQKHWRG 400
+ +Q + + +L R ++M + YR+M EE A+I+QK+ R
Sbjct: 809 WAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARA 868
Query: 401 YRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKK 460
+ R+ F R+ ++ + +QR K + ++ L L L R +++K
Sbjct: 869 WLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLV---EKLTSLAALRAGDVEK 925
Query: 461 RVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQ 520
++L A+ ++ H R EE+ +++R+A + + +
Sbjct: 926 ------------------IQKLEAELEKAATH---RRNYEEKGKRYRDA----VEEKLAK 960
Query: 521 LMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHLT 555
L K S E + ++ +L L + + K K +LT
Sbjct: 961 LQKHNSELETQKEQIQLKL-QEKTEELKEKMDNLT 994
Score = 31.2 bits (69), Expect = 2.8
Identities = 22/84 (26%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Query: 336 LLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIV-HPGQV---EKHYREMEEKSA 391
+L ++ D K ++ R ++ S + Q +I GQV EK + +S
Sbjct: 701 ILMTKQELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSC 760
Query: 392 LIIQKHWRGYRERKNFHQQRQSLI 415
+++QKH RG+ +RK F ++R++ +
Sbjct: 761 VMVQKHMRGWLQRKKFLRERRAAL 784
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 42.7 bits (99), Expect = 0.001
Identities = 52/207 (25%), Positives = 91/207 (43%), Gaps = 19/207 (9%)
Query: 320 AVIALQRSFRSKRSKML-----LEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSML--- 371
A+ LQ+ ++K +K+ E+ ++EEE+ K Q +L+RQ+ L R+ +
Sbjct: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
Query: 372 --EIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALK 429
E+ Q E R+ E++ AL R RE + QQ ++L + + K
Sbjct: 776 EEELARRKQEEALRRQREQEIAL------RRQREEEERQQQEEALRRLEERRREEEERRK 829
Query: 430 FLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQER 489
RK+++ A W +E R E + R+++ R L + +EL Q Q+
Sbjct: 830 QEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR-LRHEEEERKRKELEVQRQKE 888
Query: 490 L--QHYFMGRALEERAQQHREALIAQI 514
L Q AL QQ ++ +AQ+
Sbjct: 889 LMRQRQQQQEALRRLQQQQQQQQLAQM 915
Score = 30.0 bits (66), Expect = 6.3
Identities = 35/149 (23%), Positives = 66/149 (44%), Gaps = 20/149 (13%)
Query: 287 QEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRS----FRSKRSKMLLEINRQ 342
+E+ Q+ Q L + + Q + KLPS+ Q+S +S+ + L EI +
Sbjct: 887 KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 946
Query: 343 KEEEDLKLQLQLQRQ-----RAMRLSRELQLSML----EIVHPGQVEKHYREMEEKSALI 393
+EE + +L+ + +RQ +A++ ++ Q L + P K E++++ A
Sbjct: 947 EEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1006
Query: 394 IQK-------HWRGYRERKNFHQQRQSLI 415
+QK H + R R N H + I
Sbjct: 1007 MQKQQQQQQQHQQPNRARNNTHSNLHTSI 1035
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 42.7 bits (99), Expect = 0.001
Identities = 52/207 (25%), Positives = 91/207 (43%), Gaps = 19/207 (9%)
Query: 320 AVIALQRSFRSKRSKML-----LEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSML--- 371
A+ LQ+ ++K +K+ E+ ++EEE+ K Q +L+RQ+ L R+ +
Sbjct: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802
Query: 372 --EIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALK 429
E+ Q E R+ E++ AL R RE + QQ ++L + + K
Sbjct: 803 EEELARRKQEEALRRQREQEIAL------RRQREEEERQQQEEALRRLEERRREEEERRK 856
Query: 430 FLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQER 489
RK+++ A W +E R E + R+++ R L + +EL Q Q+
Sbjct: 857 QEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR-LRHEEEERKRKELEVQRQKE 915
Query: 490 L--QHYFMGRALEERAQQHREALIAQI 514
L Q AL QQ ++ +AQ+
Sbjct: 916 LMRQRQQQQEALRRLQQQQQQQQLAQM 942
Score = 30.0 bits (66), Expect = 6.3
Identities = 35/149 (23%), Positives = 66/149 (44%), Gaps = 20/149 (13%)
Query: 287 QEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRS----FRSKRSKMLLEINRQ 342
+E+ Q+ Q L + + Q + KLPS+ Q+S +S+ + L EI +
Sbjct: 914 KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 973
Query: 343 KEEEDLKLQLQLQRQ-----RAMRLSRELQLSML----EIVHPGQVEKHYREMEEKSALI 393
+EE + +L+ + +RQ +A++ ++ Q L + P K E++++ A
Sbjct: 974 EEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1033
Query: 394 IQK-------HWRGYRERKNFHQQRQSLI 415
+QK H + R R N H + I
Sbjct: 1034 MQKQQQQQQQHQQPNRARNNTHSNLHTSI 1062
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 42.7 bits (99), Expect = 0.001
Identities = 52/207 (25%), Positives = 91/207 (43%), Gaps = 19/207 (9%)
Query: 320 AVIALQRSFRSKRSKML-----LEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSML--- 371
A+ LQ+ ++K +K+ E+ ++EEE+ K Q +L+RQ+ L R+ +
Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
Query: 372 --EIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALK 429
E+ Q E R+ E++ AL R RE + QQ ++L + + K
Sbjct: 782 EEELARRKQEEALRRQREQEIAL------RRQREEEERQQQEEALRRLEERRREEEERRK 835
Query: 430 FLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQER 489
RK+++ A W +E R E + R+++ R L + +EL Q Q+
Sbjct: 836 QEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR-LRHEEEERKRKELEVQRQKE 894
Query: 490 L--QHYFMGRALEERAQQHREALIAQI 514
L Q AL QQ ++ +AQ+
Sbjct: 895 LMRQRQQQQEALRRLQQQQQQQQLAQM 921
Score = 30.0 bits (66), Expect = 6.3
Identities = 35/149 (23%), Positives = 66/149 (44%), Gaps = 20/149 (13%)
Query: 287 QEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRS----FRSKRSKMLLEINRQ 342
+E+ Q+ Q L + + Q + KLPS+ Q+S +S+ + L EI +
Sbjct: 893 KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 952
Query: 343 KEEEDLKLQLQLQRQ-----RAMRLSRELQLSML----EIVHPGQVEKHYREMEEKSALI 393
+EE + +L+ + +RQ +A++ ++ Q L + P K E++++ A
Sbjct: 953 EEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1012
Query: 394 IQK-------HWRGYRERKNFHQQRQSLI 415
+QK H + R R N H + I
Sbjct: 1013 MQKQQQQQQQHQQPNRARNNTHSNLHTSI 1041
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 42.7 bits (99), Expect = 0.001
Identities = 52/207 (25%), Positives = 91/207 (43%), Gaps = 19/207 (9%)
Query: 320 AVIALQRSFRSKRSKML-----LEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSML--- 371
A+ LQ+ ++K +K+ E+ ++EEE+ K Q +L+RQ+ L R+ +
Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
Query: 372 --EIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALK 429
E+ Q E R+ E++ AL R RE + QQ ++L + + K
Sbjct: 782 EEELARRKQEEALRRQREQEIAL------RRQREEEERQQQEEALRRLEERRREEEERRK 835
Query: 430 FLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQER 489
RK+++ A W +E R E + R+++ R L + +EL Q Q+
Sbjct: 836 QEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR-LRHEEEERKRKELEVQRQKE 894
Query: 490 L--QHYFMGRALEERAQQHREALIAQI 514
L Q AL QQ ++ +AQ+
Sbjct: 895 LMRQRQQQQEALRRLQQQQQQQQLAQM 921
Score = 30.0 bits (66), Expect = 6.3
Identities = 35/149 (23%), Positives = 66/149 (44%), Gaps = 20/149 (13%)
Query: 287 QEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRS----FRSKRSKMLLEINRQ 342
+E+ Q+ Q L + + Q + KLPS+ Q+S +S+ + L EI +
Sbjct: 893 KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 952
Query: 343 KEEEDLKLQLQLQRQ-----RAMRLSRELQLSML----EIVHPGQVEKHYREMEEKSALI 393
+EE + +L+ + +RQ +A++ ++ Q L + P K E++++ A
Sbjct: 953 EEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1012
Query: 394 IQK-------HWRGYRERKNFHQQRQSLI 415
+QK H + R R N H + I
Sbjct: 1013 MQKQQQQQQQHQQPNRARNNTHSNLHTSI 1041
>gi|21450705 leucine rich repeat containing 45 [Homo sapiens]
Length = 670
Score = 42.4 bits (98), Expect = 0.001
Identities = 86/349 (24%), Positives = 145/349 (41%), Gaps = 33/349 (9%)
Query: 208 YSILDEVIFKLFSTPSPVIRST--ATKLLLLMAESHQEILILLRQSTCYKGLRRLLSKQE 265
+SI++ + KL T + + S A L L+A + QE L L ++ K L+ L +QE
Sbjct: 295 HSIINALKAKLQMTEAALALSEQKAQDLGELLATAEQEQLSLSQRQA--KELK--LEQQE 350
Query: 266 TGTEFSQELRQLVG-----LLSPMVYQEVEEQKLHQAACLIQAY-----------WKGFQ 309
S+ LR L LL E+E + Q L Q + Q
Sbjct: 351 AAERESKLLRDLSAANEKNLLLQNQVDELERKFRCQQEQLFQTRQEMTSMSAELKMRAIQ 410
Query: 310 TRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLS 369
+RL S R K + + R EE + +Q ++QR A RLS E +LS
Sbjct: 411 AEERLDMEKRRCRQSLEDSESLRIKEVEHMTRHLEESEKAMQERVQRLEAARLSLEEELS 470
Query: 370 MLE---IVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRA 426
++ + GQ E+ + + ++ L Q+ ++ Q + + LQ+
Sbjct: 471 RVKAAALSERGQAEEELIKAKSQARLEEQQRLAHLEDKLRLLAQAR---DEAQGACLQQK 527
Query: 427 ALKFLAKCRKKK---KLFAPWRGLQELTDARRVELKKRVDDYVRRHLG-SPMSDVVSREL 482
+ A+ R + ++ R L+EL ++ ++RV + R + + + EL
Sbjct: 528 QVVAEAQTRVSQLGLQVEGLRRRLEELQQELSLKDQERVAEVSRVRVELQEQNGRLQAEL 587
Query: 483 HAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAE 531
AQ R + + R L+ A HREAL+ + S N L + L+EAE
Sbjct: 588 AAQEALREKAAALERQLKVMASDHREALLDRESENA-SLREKLRLREAE 635
Score = 40.4 bits (93), Expect = 0.005
Identities = 61/284 (21%), Positives = 123/284 (43%), Gaps = 26/284 (9%)
Query: 272 QELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSK 331
++ +Q + L+ + Q E K +A+ + Q ++ L + S + AL+ +
Sbjct: 254 EKSKQFLDLMETIDKQREEMAKSSRASAA-----RVGQLQEALNERHSIINALKAKLQMT 308
Query: 332 RSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSA 391
+ + L +++ +DL L Q + LS+ Q L++ E+ + + + SA
Sbjct: 309 EAALALS---EQKAQDLGELLATAEQEQLSLSQR-QAKELKLEQQEAAERESKLLRDLSA 364
Query: 392 L----IIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGL 447
++ ++ ERK F Q++ L + + +T A LK A +++ R
Sbjct: 365 ANEKNLLLQNQVDELERK-FRCQQEQLFQTRQEMTSMSAELKMRAIQAEERLDMEKRRCR 423
Query: 448 QELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGR-ALEERAQQH 506
Q L D+ + +K+ +++ RHL E QER+Q R +LEE +
Sbjct: 424 QSLEDSESLRIKEV--EHMTRHL---------EESEKAMQERVQRLEAARLSLEEELSRV 472
Query: 507 REALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAK 550
+ A +++ E+L+KA S E ++ L + A+A+
Sbjct: 473 KAAALSERGQAEEELIKAKSQARLEEQQRLAHLEDKLRLLAQAR 516
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 41.6 bits (96), Expect = 0.002
Identities = 53/258 (20%), Positives = 114/258 (44%), Gaps = 38/258 (14%)
Query: 303 AYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRL 362
AY +G R +++ AV+ ++ ++K+ L K+ D+ L+++ + R+
Sbjct: 695 AYKQG-DLRGTCQRMAEAVLGTHDDWQIGKTKIFL-----KDHHDMLLEVERDKAITDRV 748
Query: 363 SRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNF-------------HQ 409
+L+ V G ++ + +A +IQ+HWRG+ RKN+ H+
Sbjct: 749 I------LLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHR 802
Query: 410 QRQSLIEYKAAVTLQRAALKFLAKCR----KKKKLFAPWRGLQELTDARRVELKKRVDDY 465
R+ +Y+ A ++ ++F A+CR +K W L AR + + +R+
Sbjct: 803 SRKLHQQYRLA---RQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGM-IARRLHQR 858
Query: 466 VRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAP 525
+R + + + ++ +E+L+ + +E A++ + +AQ++ E +
Sbjct: 859 LRAEY---LWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAR--EDAEREL 913
Query: 526 SLKEAEGKEPELFLSRSR 543
KEA ++ EL R
Sbjct: 914 KEKEAARRKKELLEQMER 931
Score = 32.7 bits (73), Expect = 0.98
Identities = 17/51 (33%), Positives = 25/51 (49%)
Query: 293 KLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQK 343
KL AA LIQ +W+G RK + + LQ RS++ + RQ+
Sbjct: 766 KLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQR 816
Score = 31.2 bits (69), Expect = 2.8
Identities = 50/229 (21%), Positives = 92/229 (40%), Gaps = 38/229 (16%)
Query: 288 EVEEQK-LHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEE 346
EVE K + L+Q +GF+ R KL +A +QR +R + +
Sbjct: 737 EVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGL------- 789
Query: 347 DLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKN 406
++L R +A+ SR+L + YR + + + Q R Y RK
Sbjct: 790 ---MRLGFLRLQALHRSRKL-------------HQQYR-LARQRIIQFQARCRAYLVRKA 832
Query: 407 FHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYV 466
F + A +T+Q A +A+ R ++L A + E R E +K +
Sbjct: 833 FRHR------LWAVLTVQAYARGMIAR-RLHQRLRAEYLWRLEAEKMRLAEEEK-----L 880
Query: 467 RRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEER-AQQHREALIAQI 514
R+ + + + + H + +L R L+E+ A + ++ L+ Q+
Sbjct: 881 RKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQM 929
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 41.6 bits (96), Expect = 0.002
Identities = 53/258 (20%), Positives = 114/258 (44%), Gaps = 38/258 (14%)
Query: 303 AYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRL 362
AY +G R +++ AV+ ++ ++K+ L K+ D+ L+++ + R+
Sbjct: 695 AYKQG-DLRGTCQRMAEAVLGTHDDWQIGKTKIFL-----KDHHDMLLEVERDKAITDRV 748
Query: 363 SRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNF-------------HQ 409
+L+ V G ++ + +A +IQ+HWRG+ RKN+ H+
Sbjct: 749 I------LLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHR 802
Query: 410 QRQSLIEYKAAVTLQRAALKFLAKCR----KKKKLFAPWRGLQELTDARRVELKKRVDDY 465
R+ +Y+ A ++ ++F A+CR +K W L AR + + +R+
Sbjct: 803 SRKLHQQYRLA---RQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGM-IARRLHQR 858
Query: 466 VRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAP 525
+R + + + ++ +E+L+ + +E A++ + +AQ++ E +
Sbjct: 859 LRAEY---LWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAR--EDAEREL 913
Query: 526 SLKEAEGKEPELFLSRSR 543
KEA ++ EL R
Sbjct: 914 KEKEAARRKKELLEQMER 931
Score = 32.7 bits (73), Expect = 0.98
Identities = 17/51 (33%), Positives = 25/51 (49%)
Query: 293 KLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQK 343
KL AA LIQ +W+G RK + + LQ RS++ + RQ+
Sbjct: 766 KLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQR 816
Score = 31.2 bits (69), Expect = 2.8
Identities = 50/229 (21%), Positives = 92/229 (40%), Gaps = 38/229 (16%)
Query: 288 EVEEQK-LHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEE 346
EVE K + L+Q +GF+ R KL +A +QR +R + +
Sbjct: 737 EVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGL------- 789
Query: 347 DLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKN 406
++L R +A+ SR+L + YR + + + Q R Y RK
Sbjct: 790 ---MRLGFLRLQALHRSRKL-------------HQQYR-LARQRIIQFQARCRAYLVRKA 832
Query: 407 FHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYV 466
F + A +T+Q A +A+ R ++L A + E R E +K +
Sbjct: 833 FRHR------LWAVLTVQAYARGMIAR-RLHQRLRAEYLWRLEAEKMRLAEEEK-----L 880
Query: 467 RRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEER-AQQHREALIAQI 514
R+ + + + + H + +L R L+E+ A + ++ L+ Q+
Sbjct: 881 RKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQM 929
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 41.6 bits (96), Expect = 0.002
Identities = 53/258 (20%), Positives = 114/258 (44%), Gaps = 38/258 (14%)
Query: 303 AYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRL 362
AY +G R +++ AV+ ++ ++K+ L K+ D+ L+++ + R+
Sbjct: 695 AYKQG-DLRGTCQRMAEAVLGTHDDWQIGKTKIFL-----KDHHDMLLEVERDKAITDRV 748
Query: 363 SRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNF-------------HQ 409
+L+ V G ++ + +A +IQ+HWRG+ RKN+ H+
Sbjct: 749 I------LLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHR 802
Query: 410 QRQSLIEYKAAVTLQRAALKFLAKCR----KKKKLFAPWRGLQELTDARRVELKKRVDDY 465
R+ +Y+ A ++ ++F A+CR +K W L AR + + +R+
Sbjct: 803 SRKLHQQYRLA---RQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGM-IARRLHQR 858
Query: 466 VRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAP 525
+R + + + ++ +E+L+ + +E A++ + +AQ++ E +
Sbjct: 859 LRAEY---LWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAR--EDAEREL 913
Query: 526 SLKEAEGKEPELFLSRSR 543
KEA ++ EL R
Sbjct: 914 KEKEAARRKKELLEQMER 931
Score = 32.7 bits (73), Expect = 0.98
Identities = 17/51 (33%), Positives = 25/51 (49%)
Query: 293 KLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQK 343
KL AA LIQ +W+G RK + + LQ RS++ + RQ+
Sbjct: 766 KLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQR 816
Score = 31.2 bits (69), Expect = 2.8
Identities = 50/229 (21%), Positives = 92/229 (40%), Gaps = 38/229 (16%)
Query: 288 EVEEQK-LHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEE 346
EVE K + L+Q +GF+ R KL +A +QR +R + +
Sbjct: 737 EVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGL------- 789
Query: 347 DLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKN 406
++L R +A+ SR+L + YR + + + Q R Y RK
Sbjct: 790 ---MRLGFLRLQALHRSRKL-------------HQQYR-LARQRIIQFQARCRAYLVRKA 832
Query: 407 FHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYV 466
F + A +T+Q A +A+ R ++L A + E R E +K +
Sbjct: 833 FRHR------LWAVLTVQAYARGMIAR-RLHQRLRAEYLWRLEAEKMRLAEEEK-----L 880
Query: 467 RRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEER-AQQHREALIAQI 514
R+ + + + + H + +L R L+E+ A + ++ L+ Q+
Sbjct: 881 RKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQM 929
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 41.2 bits (95), Expect = 0.003
Identities = 35/186 (18%), Positives = 84/186 (45%), Gaps = 16/186 (8%)
Query: 344 EEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRE 403
+ D KL +LQ Q R + Q+ +L + + + +E +++ A++ + R +E
Sbjct: 879 DNADAKLLRKLQAQEIAR--QAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKE 936
Query: 404 RKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVD 463
+ +Q++ + + + + + + +KKKK +E +A+ +E +KR+
Sbjct: 937 QIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKK--------EEAANAKLLEAEKRIK 988
Query: 464 DYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMK 523
+ R + + H + + R QH + +A+E R + + + Q + ++L K
Sbjct: 989 EKEMRRQQAVLLK------HQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNK 1042
Query: 524 APSLKE 529
L++
Sbjct: 1043 ERKLEQ 1048
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 40.8 bits (94), Expect = 0.004
Identities = 87/361 (24%), Positives = 147/361 (40%), Gaps = 55/361 (15%)
Query: 255 KGLRRLLSKQETGTEFSQELRQL-VGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKR 313
K + + + K +T E +EL++L ++ E + +++Q IQA K + + +
Sbjct: 1229 KEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQAL-KDTKPQVQ 1287
Query: 314 LKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEI 373
K++ ++ Q ++K L R K E+ K Q+ L+R+RA S+E Q++ E
Sbjct: 1288 TKEVVQEILQFQEDPQTKEEVASL---RAKLSEEQKKQVDLERERA---SQEEQIARKE- 1340
Query: 374 VHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQ----RAALK 429
E+ ++Q+ Y E + + E Q RA L+
Sbjct: 1341 ----------EELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELR 1390
Query: 430 FLAKCRKKKKLFAPWRGLQELTDAR--RVELKKRVDDYVRRHLGSPMSDVVSRE------ 481
L + R + + R L+EL R R E ++ V +R + +RE
Sbjct: 1391 RLQRRRTELE-----RQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQ 1445
Query: 482 ---LHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQL-MKAPSLKEAEGKEPEL 537
L Q+ +H + LEE +QHR L + +E L K +L++AE KE ++
Sbjct: 1446 KVVLQQDPQQAREHALLRLQLEE--EQHRRQL---LEGELETLRRKLAALEKAEVKE-KV 1499
Query: 538 FLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESGD--EIDVPKDELSIELENLFIGGT 595
LS S V + + LK L EES E+DV L L L +
Sbjct: 1500 VLSESVQVEKGDTEQEIQRLK-------SSLEEESRSKRELDVEVSRLEARLSELEFHNS 1552
Query: 596 K 596
K
Sbjct: 1553 K 1553
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 40.4 bits (93), Expect = 0.005
Identities = 78/351 (22%), Positives = 141/351 (40%), Gaps = 38/351 (10%)
Query: 244 ILILLRQSTCYKGLRRLLSK-QETGTEFSQELRQLVGLLSPMVYQEVE--EQKLHQAACL 300
+L + RQ + + L K QE + ++E+ +L G ++ + + EQ +A
Sbjct: 869 LLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELC 928
Query: 301 IQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAM 360
+A + R ++L V L+ + E +RQ + E +LQ +Q A
Sbjct: 929 AEAEETRGRLAARKQELELVVSELEARVGEEE-----ECSRQMQTEKKRLQQHIQELEAH 983
Query: 361 RLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAA 420
+ E L++ E ++ EE L+ ++ + +ERK + L E+ +
Sbjct: 984 LEAEEGARQKLQL-EKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDR---LAEFSSQ 1039
Query: 421 VTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVD-DYVRRHLGSPMSDVVS 479
+ +K L K R K + + ++ D R E K R + + ++R L D S
Sbjct: 1040 AAEEEEKVKSLNKLRLKYEAT-----IADMEDRLRKEEKGRQELEKLKRRL-----DGES 1089
Query: 480 RELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAE-GKEPELF 538
EL Q E+ QQ E L AQ+ E+L A + E E G +L
Sbjct: 1090 SELQEQMVEQ--------------QQRAEELRAQLGRKEEELQAALARAEDEGGARAQLL 1135
Query: 539 LSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESGDEIDVPKDELSIELEN 589
S AA A+ + + +K + G+E++ + EL L++
Sbjct: 1136 KSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDS 1186
Score = 33.5 bits (75), Expect = 0.57
Identities = 53/253 (20%), Positives = 108/253 (42%), Gaps = 35/253 (13%)
Query: 269 EFSQELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSF 328
E ++LR++ + + ++EVEE + + + + + ++ KRLK L + V+ LQ
Sbjct: 1667 EAVKQLRKMQAQMKEL-WREVEETRTSRE----EIFSQNRESEKRLKGLEAEVLRLQEEL 1721
Query: 329 R-SKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREME 387
S R++ + +R + +++ L + + R+L+ + GQ+E+ E +
Sbjct: 1722 AASDRARRQAQQDRDEMADEVA-NGNLSKAAILEEKRQLEGRL------GQLEEELEEEQ 1774
Query: 388 EKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGL 447
S L+ ++ R+ L++ ++ T A F AK ++ R +
Sbjct: 1775 SNSELLNDRY-------------RKLLLQVESLTTELSAERSFSAKAESGRQQLE--RQI 1819
Query: 448 QELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHR 507
QEL R L + RH M+ AQA+E+L+ R L + +
Sbjct: 1820 QEL----RGRLGEEDAGARARH---KMTIAALESKLAQAEEQLEQETRERILSGKLVRRA 1872
Query: 508 EALIAQISTNVEQ 520
E + ++ VE+
Sbjct: 1873 EKRLKEVVLQVEE 1885
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 40.4 bits (93), Expect = 0.005
Identities = 78/351 (22%), Positives = 141/351 (40%), Gaps = 38/351 (10%)
Query: 244 ILILLRQSTCYKGLRRLLSK-QETGTEFSQELRQLVGLLSPMVYQEVE--EQKLHQAACL 300
+L + RQ + + L K QE + ++E+ +L G ++ + + EQ +A
Sbjct: 861 LLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELC 920
Query: 301 IQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAM 360
+A + R ++L V L+ + E +RQ + E +LQ +Q A
Sbjct: 921 AEAEETRGRLAARKQELELVVSELEARVGEEE-----ECSRQMQTEKKRLQQHIQELEAH 975
Query: 361 RLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAA 420
+ E L++ E ++ EE L+ ++ + +ERK + L E+ +
Sbjct: 976 LEAEEGARQKLQL-EKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDR---LAEFSSQ 1031
Query: 421 VTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVD-DYVRRHLGSPMSDVVS 479
+ +K L K R K + + ++ D R E K R + + ++R L D S
Sbjct: 1032 AAEEEEKVKSLNKLRLKYEAT-----IADMEDRLRKEEKGRQELEKLKRRL-----DGES 1081
Query: 480 RELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAE-GKEPELF 538
EL Q E+ QQ E L AQ+ E+L A + E E G +L
Sbjct: 1082 SELQEQMVEQ--------------QQRAEELRAQLGRKEEELQAALARAEDEGGARAQLL 1127
Query: 539 LSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESGDEIDVPKDELSIELEN 589
S AA A+ + + +K + G+E++ + EL L++
Sbjct: 1128 KSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDS 1178
Score = 33.5 bits (75), Expect = 0.57
Identities = 53/253 (20%), Positives = 108/253 (42%), Gaps = 35/253 (13%)
Query: 269 EFSQELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSF 328
E ++LR++ + + ++EVEE + + + + + ++ KRLK L + V+ LQ
Sbjct: 1659 EAVKQLRKMQAQMKEL-WREVEETRTSRE----EIFSQNRESEKRLKGLEAEVLRLQEEL 1713
Query: 329 R-SKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREME 387
S R++ + +R + +++ L + + R+L+ + GQ+E+ E +
Sbjct: 1714 AASDRARRQAQQDRDEMADEVA-NGNLSKAAILEEKRQLEGRL------GQLEEELEEEQ 1766
Query: 388 EKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGL 447
S L+ ++ R+ L++ ++ T A F AK ++ R +
Sbjct: 1767 SNSELLNDRY-------------RKLLLQVESLTTELSAERSFSAKAESGRQQLE--RQI 1811
Query: 448 QELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHR 507
QEL R L + RH M+ AQA+E+L+ R L + +
Sbjct: 1812 QEL----RGRLGEEDAGARARH---KMTIAALESKLAQAEEQLEQETRERILSGKLVRRA 1864
Query: 508 EALIAQISTNVEQ 520
E + ++ VE+
Sbjct: 1865 EKRLKEVVLQVEE 1877
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 40.4 bits (93), Expect = 0.005
Identities = 78/351 (22%), Positives = 141/351 (40%), Gaps = 38/351 (10%)
Query: 244 ILILLRQSTCYKGLRRLLSK-QETGTEFSQELRQLVGLLSPMVYQEVE--EQKLHQAACL 300
+L + RQ + + L K QE + ++E+ +L G ++ + + EQ +A
Sbjct: 902 LLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELC 961
Query: 301 IQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAM 360
+A + R ++L V L+ + E +RQ + E +LQ +Q A
Sbjct: 962 AEAEETRGRLAARKQELELVVSELEARVGEEE-----ECSRQMQTEKKRLQQHIQELEAH 1016
Query: 361 RLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAA 420
+ E L++ E ++ EE L+ ++ + +ERK + L E+ +
Sbjct: 1017 LEAEEGARQKLQL-EKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDR---LAEFSSQ 1072
Query: 421 VTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVD-DYVRRHLGSPMSDVVS 479
+ +K L K R K + + ++ D R E K R + + ++R L D S
Sbjct: 1073 AAEEEEKVKSLNKLRLKYEAT-----IADMEDRLRKEEKGRQELEKLKRRL-----DGES 1122
Query: 480 RELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAE-GKEPELF 538
EL Q E+ QQ E L AQ+ E+L A + E E G +L
Sbjct: 1123 SELQEQMVEQ--------------QQRAEELRAQLGRKEEELQAALARAEDEGGARAQLL 1168
Query: 539 LSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESGDEIDVPKDELSIELEN 589
S AA A+ + + +K + G+E++ + EL L++
Sbjct: 1169 KSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDS 1219
Score = 33.5 bits (75), Expect = 0.57
Identities = 53/253 (20%), Positives = 108/253 (42%), Gaps = 35/253 (13%)
Query: 269 EFSQELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSF 328
E ++LR++ + + ++EVEE + + + + + ++ KRLK L + V+ LQ
Sbjct: 1700 EAVKQLRKMQAQMKEL-WREVEETRTSRE----EIFSQNRESEKRLKGLEAEVLRLQEEL 1754
Query: 329 R-SKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREME 387
S R++ + +R + +++ L + + R+L+ + GQ+E+ E +
Sbjct: 1755 AASDRARRQAQQDRDEMADEVA-NGNLSKAAILEEKRQLEGRL------GQLEEELEEEQ 1807
Query: 388 EKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGL 447
S L+ ++ R+ L++ ++ T A F AK ++ R +
Sbjct: 1808 SNSELLNDRY-------------RKLLLQVESLTTELSAERSFSAKAESGRQQLE--RQI 1852
Query: 448 QELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHR 507
QEL R L + RH M+ AQA+E+L+ R L + +
Sbjct: 1853 QEL----RGRLGEEDAGARARH---KMTIAALESKLAQAEEQLEQETRERILSGKLVRRA 1905
Query: 508 EALIAQISTNVEQ 520
E + ++ VE+
Sbjct: 1906 EKRLKEVVLQVEE 1918
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 40.4 bits (93), Expect = 0.005
Identities = 43/212 (20%), Positives = 95/212 (44%), Gaps = 15/212 (7%)
Query: 325 QRSFRSKRSKMLLEINRQKEEEDLKLQL-QLQRQRAMRLSRELQ----LSMLEIVHPGQV 379
QR +R + ++ RQK EED + +L +++ +R RL + LQ + ++ Q+
Sbjct: 540 QRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI 599
Query: 380 EKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKK 439
E+ + +++EK+ ++ + +K ++ +E + + L++L + ++++
Sbjct: 600 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 659
Query: 440 LFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRAL 499
QEL ++ E ++R+ + + RE + QER + R
Sbjct: 660 -------HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE---QERRE 709
Query: 500 EERAQQHREALIAQISTNVEQLMKAPSLKEAE 531
+ER +Q R+ + E+L L+E E
Sbjct: 710 QERREQERQLAEQERRREQERLQAERELQERE 741
Score = 38.5 bits (88), Expect = 0.018
Identities = 51/230 (22%), Positives = 96/230 (41%), Gaps = 16/230 (6%)
Query: 312 KRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSML 371
KR ++L + A +R + K K +Q E++ ++ + ++ + RL+ E
Sbjct: 573 KREERLRKVLQARERVEQMKEEK-----KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKA 627
Query: 372 EIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAA-LKF 430
+VE ++ EE L W E + HQ+ + + L++AA K
Sbjct: 628 AAKKMEEVEARRKQEEEARRL----RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR 683
Query: 431 LAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQE-- 488
LA+ R++++ R + RR + ++ + + + + E Q +E
Sbjct: 684 LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKA 743
Query: 489 -RLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPEL 537
RLQ + R LEE+ ++ + +A+ EQ KA KEA G L
Sbjct: 744 LRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA---KEAAGASKAL 790
Score = 33.5 bits (75), Expect = 0.57
Identities = 37/143 (25%), Positives = 67/143 (46%), Gaps = 18/143 (12%)
Query: 255 KGLRRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRL 314
K + + + E + +E R+L L Q+ EE++ HQ L+Q K + ++RL
Sbjct: 626 KAAAKKMEEVEARRKQEEEARRLRWL------QQEEEERRHQE--LLQK--KKEEEQERL 675
Query: 315 KKLPSAVIALQRSFRSKRSKMLLEINRQKEE--------EDLKLQLQLQRQRAMRLSREL 366
+K A ++ + +R + E R+++E ++ +L Q +R+ RL E
Sbjct: 676 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAER 735
Query: 367 QLSMLEIVHPGQVEKHYREMEEK 389
+L E Q E+ RE+EEK
Sbjct: 736 ELQEREKALRLQKEQLQRELEEK 758
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 40.4 bits (93), Expect = 0.005
Identities = 43/212 (20%), Positives = 95/212 (44%), Gaps = 15/212 (7%)
Query: 325 QRSFRSKRSKMLLEINRQKEEEDLKLQL-QLQRQRAMRLSRELQ----LSMLEIVHPGQV 379
QR +R + ++ RQK EED + +L +++ +R RL + LQ + ++ Q+
Sbjct: 536 QRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI 595
Query: 380 EKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKK 439
E+ + +++EK+ ++ + +K ++ +E + + L++L + ++++
Sbjct: 596 EQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 655
Query: 440 LFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRAL 499
QEL ++ E ++R+ + + RE + QER + R
Sbjct: 656 -------HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE---QERRE 705
Query: 500 EERAQQHREALIAQISTNVEQLMKAPSLKEAE 531
+ER +Q R+ + E+L L+E E
Sbjct: 706 QERREQERQLAEQERRREQERLQAERELQERE 737
Score = 38.5 bits (88), Expect = 0.018
Identities = 51/230 (22%), Positives = 96/230 (41%), Gaps = 16/230 (6%)
Query: 312 KRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSML 371
KR ++L + A +R + K K +Q E++ ++ + ++ + RL+ E
Sbjct: 569 KREERLRKVLQARERVEQMKEEK-----KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKA 623
Query: 372 EIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAA-LKF 430
+VE ++ EE L W E + HQ+ + + L++AA K
Sbjct: 624 AAKKMEEVEARRKQEEEARRL----RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR 679
Query: 431 LAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQE-- 488
LA+ R++++ R + RR + ++ + + + + E Q +E
Sbjct: 680 LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKA 739
Query: 489 -RLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPEL 537
RLQ + R LEE+ ++ + +A+ EQ KA KEA G L
Sbjct: 740 LRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA---KEAAGASKAL 786
Score = 33.5 bits (75), Expect = 0.57
Identities = 37/143 (25%), Positives = 67/143 (46%), Gaps = 18/143 (12%)
Query: 255 KGLRRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRL 314
K + + + E + +E R+L L Q+ EE++ HQ L+Q K + ++RL
Sbjct: 622 KAAAKKMEEVEARRKQEEEARRLRWL------QQEEEERRHQE--LLQK--KKEEEQERL 671
Query: 315 KKLPSAVIALQRSFRSKRSKMLLEINRQKEE--------EDLKLQLQLQRQRAMRLSREL 366
+K A ++ + +R + E R+++E ++ +L Q +R+ RL E
Sbjct: 672 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAER 731
Query: 367 QLSMLEIVHPGQVEKHYREMEEK 389
+L E Q E+ RE+EEK
Sbjct: 732 ELQEREKALRLQKEQLQRELEEK 754
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 39.3 bits (90), Expect = 0.010
Identities = 54/266 (20%), Positives = 120/266 (45%), Gaps = 46/266 (17%)
Query: 324 LQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHY 383
L+ +SKM +K+E +L+ +L+ Q R M L + +EI +V K+Y
Sbjct: 1498 LKGEMEDDKSKM------EKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNY 1551
Query: 384 ---REMEEKSALIIQKHWRGYRERKN--FHQQRQSLIEYKAAVTLQRAALKF-------- 430
+++E K + +H++ E K+ + + ++ + V +A L+
Sbjct: 1552 NQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHV 1611
Query: 431 -LAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQER 489
L+ K+++L A L+ + A+ ELK++ + + + ++L +Q +E+
Sbjct: 1612 NLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIA---------AIKKQLLSQMEEK 1662
Query: 490 LQHYFMGRALEERAQQHREALIAQISTNVEQLMK-----APSLKEAEGKEPE-LFLSRS- 542
EE+ ++ E+ +++++T +++ + LK E + E L + RS
Sbjct: 1663 ----------EEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSA 1712
Query: 543 RPVAAKAKQAHLTTLKHIQAPWWKKL 568
+ VAA +Q + +Q + +K+
Sbjct: 1713 KNVAAYTEQEEADSQGCVQKTYEEKI 1738
Score = 35.0 bits (79), Expect = 0.20
Identities = 54/224 (24%), Positives = 95/224 (42%), Gaps = 36/224 (16%)
Query: 315 KKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIV 374
+KL ++ LQ+ R +L Q+E E LK + +R+ ++ +E LE+
Sbjct: 1940 QKLGKEIVRLQKDLR------MLRKEHQQELEILKKEYDQEREEKIKQEQE----DLELK 1989
Query: 375 HPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQS-LIEYKAAVTLQRAALKFLAK 433
H +++ RE + A Q+ +E N Q+ ++ L+E T Q LK +A+
Sbjct: 1990 HNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQ--LLKKIAE 2047
Query: 434 CRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHY 493
K L + +E+ DAR E+ +V R+L Q +E LQ
Sbjct: 2048 --KDDDLKRTAKRYEEILDAREEEMTAKV-----------------RDLQTQLEE-LQKK 2087
Query: 494 FMGRALEERAQQHREALIAQISTNVEQ---LMKAPSLKEAEGKE 534
+ + +E + I ++ T + Q L+ LKE E +E
Sbjct: 2088 YQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFRE 2131
>gi|70980531 GGA binding partner [Homo sapiens]
Length = 441
Score = 38.9 bits (89), Expect = 0.014
Identities = 51/235 (21%), Positives = 111/235 (47%), Gaps = 35/235 (14%)
Query: 339 INRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHW 398
I Q++ L+++L++ + R+ ++++ S++E +EK + + +E+ A+ Q +
Sbjct: 132 IQLQQKISSLEIKLKVSEEEKQRIKQDVE-SLME--KHNVLEKGFLKEKEQEAISFQDRY 188
Query: 399 RGYRE---------RKNFHQQRQSLI-EYKAAVTLQRAALKFLAKCRKKKKLFAPWRGL- 447
+ +E RK H+ ++ EYKA L ++++K + +K+ + A +
Sbjct: 189 KELQEKHKQELEDMRKAGHEALSIIVDEYKA---LLQSSVKQQVEAIEKQYISAIEKQAH 245
Query: 448 --QELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQ 505
+EL +A+ L + +D + L + + + L Q+QE Q + + LEE Q+
Sbjct: 246 KCEELLNAQHQRLLEMLD--TEKEL---LKEKIKEALIQQSQE--QKEILEKCLEEERQR 298
Query: 506 HREALIAQISTNVEQLMKA---------PSLKEAEGKEPELFLSRSRPVAAKAKQ 551
++EAL++ E + A +L++A +E EL+ + K Q
Sbjct: 299 NKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQEKVSQ 353
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 38.1 bits (87), Expect = 0.023
Identities = 83/374 (22%), Positives = 157/374 (41%), Gaps = 60/374 (16%)
Query: 237 MAESHQEILILLRQSTCYKGL-----RRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEE 291
+A++ + +L++ +G RL ++E + + R+L + + +++++
Sbjct: 947 LADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELK-KDIDD 1005
Query: 292 QKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFR--SKRSKMLLEINRQKEEEDLK 349
KL L +A + T ++K L + AL S +K K L E ++Q +
Sbjct: 1006 LKL----TLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGD--- 1058
Query: 350 LQLQLQRQRAMRLSR-ELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFH 408
LQ + R L++ +L+L QVE +E++ L + R ++
Sbjct: 1059 --LQAEEDRVSALTKAKLRLEQ-------QVEDLECSLEQEKKLRMDTE----RAKRKLE 1105
Query: 409 QQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRR 468
+ E A + L+ K +KK D+ +L RV+D +
Sbjct: 1106 GDLKLTQESVADAAQDKQQLE--EKLKKK--------------DSELSQLSLRVED--EQ 1147
Query: 469 HLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKA--PS 526
LG+ M + +EL A+A+E + RA R ++ R ++ E+L +A S
Sbjct: 1148 LLGAQMQKKI-KELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGAS 1206
Query: 527 LKEAEG---KEPEL-FLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESG------DEI 576
+ EG +E EL L R AA +A + L+ QA +LGE+ ++
Sbjct: 1207 AGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKL 1266
Query: 577 DVPKDELSIELENL 590
+ K EL +E+++L
Sbjct: 1267 EKEKSELRMEVDDL 1280
Score = 30.4 bits (67), Expect = 4.8
Identities = 45/202 (22%), Positives = 87/202 (43%), Gaps = 29/202 (14%)
Query: 279 GLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKL---PSAVIALQ---RSFRSKR 332
GLL V +E+ +Q+L + L+QA +G R ++L A+ +Q R+F + +
Sbjct: 817 GLLG--VLEELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVK 874
Query: 333 SKMLLEI---------NRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHY 383
+ +++ + Q EEE L+ +L+ R + E + LE E H
Sbjct: 875 NWSWMKLFFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELE-------ETHV 927
Query: 384 REMEEKSALIIQKHWRGYRERKNF-HQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFA 442
+EK+ L +Q E+ N + + + K+ V L+ + + ++++ A
Sbjct: 928 SITQEKNDLALQLQ----AEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNA 983
Query: 443 PWRGLQELTDARRVELKKRVDD 464
+ + ELKK +DD
Sbjct: 984 DLAARRRKLEDECTELKKDIDD 1005
>gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens]
Length = 1079
Score = 38.1 bits (87), Expect = 0.023
Identities = 81/385 (21%), Positives = 163/385 (42%), Gaps = 55/385 (14%)
Query: 228 STATKLLLLMAESHQEILILLRQSTCYKGLRRLLSKQETGTEFSQELRQLVGLLSPMVYQ 287
S++T L +E+ I +L +++ + L L ++E + +++ +++ + +Q
Sbjct: 9 SSSTFTLQSSSETLFSIQLLDFKTSLLEALEELRMRREAEIHYEEQIGKIIVETQELKWQ 68
Query: 288 EVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEED 347
+ E +Q L + + + K K+L + AL+ K L ++KE E
Sbjct: 69 K--ETLQNQKETLAEQHKEAMAVFK--KQLQMKMCALEEE---KGKYQLATEIKEKEIEG 121
Query: 348 LKLQLQ-LQ------RQRAMRLSRELQLSML--EIVHP--GQVEKHYREMEEKSALIIQK 396
LK L+ LQ +++ + +++QL +L E H ++EK+Y + + L+ +
Sbjct: 122 LKETLKALQVSKYSLQKKVSEMEQKVQLHLLAKEDYHKQLSEIEKYYATITGQFGLVKEN 181
Query: 397 HWRGYRERKNFHQQRQSLI----EYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQE--- 449
H + + + Q + L + +A + + LK A K K+ ++ +E
Sbjct: 182 HEKLEQNVREAIQSNKRLSALNKKQEAEICSLKKELKKAASDLIKSKVTCQYKMGEENIN 241
Query: 450 --LTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQ--- 504
+ + + EL++R++ + EL+ + E + H ++E Q
Sbjct: 242 LTIKEQKFQELQERLN--------------MELELNEKINEEITH------IQEEKQDII 281
Query: 505 ---QHREALIAQ-ISTNVEQLMKAPSLKEA-EGKEPELFLSRSRPVAAKAKQAHLTTLKH 559
QH + L+ Q I N E + LKE + E + L R + + K +L
Sbjct: 282 ISFQHMQQLLRQQIQANTEMEAELKVLKENNQTLERDNELQREKVKENEEKFLNLQNEHE 341
Query: 560 IQAPWWKKLGEESGDEIDVPKDELS 584
WK+ EE EI+ K+ELS
Sbjct: 342 KALGTWKRHAEELNGEINKIKNELS 366
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,768,963
Number of Sequences: 37866
Number of extensions: 881281
Number of successful extensions: 4152
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 209
Number of HSP's that attempted gapping in prelim test: 3577
Number of HSP's gapped (non-prelim): 644
length of query: 598
length of database: 18,247,518
effective HSP length: 108
effective length of query: 490
effective length of database: 14,157,990
effective search space: 6937415100
effective search space used: 6937415100
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.