Guide to the Human Genome
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Search of human proteins with 170014680

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|170014680 IQ motif containing B1 isoform c [Homo sapiens]
         (465 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|170014680 IQ motif containing B1 isoform c [Homo sapiens]          918   0.0  
gi|170014684 IQ motif containing B1 isoform a [Homo sapiens]          533   e-151
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    45   1e-04
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...    45   1e-04
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...    45   1e-04
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...    45   1e-04
gi|148746195 trichohyalin [Homo sapiens]                               43   5e-04
gi|45439327 periplakin [Homo sapiens]                                  43   5e-04
gi|156119615 myosin IXA [Homo sapiens]                                 42   0.001
gi|21450705 leucine rich repeat containing 45 [Homo sapiens]           42   0.001
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s...    42   0.001
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    41   0.002
gi|32484977 angiomotin like 2 [Homo sapiens]                           41   0.003
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                      40   0.006
gi|189083800 myosin VIIA isoform 3 [Homo sapiens]                      40   0.006
gi|189083798 myosin VIIA isoform 1 [Homo sapiens]                      40   0.006
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    40   0.006
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    40   0.006
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]           39   0.008
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]           39   0.008
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]           39   0.008
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    39   0.010
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     39   0.010
gi|70980531 GGA binding partner [Homo sapiens]                         39   0.010
gi|28372509 Ymer protein short isoform [Homo sapiens]                  38   0.022
gi|126116596 asp (abnormal spindle)-like, microcephaly associate...    37   0.029
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    37   0.029
gi|17017963 forkhead box P2 isoform I [Homo sapiens]                   37   0.038
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...    37   0.038
gi|221139761 zinc finger protein 853 [Homo sapiens]                    37   0.050

>gi|170014680 IQ motif containing B1 isoform c [Homo sapiens]
          Length = 465

 Score =  918 bits (2372), Expect = 0.0
 Identities = 465/465 (100%), Positives = 465/465 (100%)

Query: 1   MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ 60
           MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ
Sbjct: 1   MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ 60

Query: 61  YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR 120
           YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR
Sbjct: 61  YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR 120

Query: 121 QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI 180
           QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI
Sbjct: 121 QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI 180

Query: 181 GSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEI 240
           GSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEI
Sbjct: 181 GSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEI 240

Query: 241 VHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAK 300
           VHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAK
Sbjct: 241 VHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAK 300

Query: 301 CRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHY 360
           CRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHY
Sbjct: 301 CRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHY 360

Query: 361 FMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAH 420
           FMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAH
Sbjct: 361 FMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAH 420

Query: 421 LTTLKHIQAPWWKKLGEESGDEIDVPKDELSIELENLFIGGTKPP 465
           LTTLKHIQAPWWKKLGEESGDEIDVPKDELSIELENLFIGGTKPP
Sbjct: 421 LTTLKHIQAPWWKKLGEESGDEIDVPKDELSIELENLFIGGTKPP 465


>gi|170014684 IQ motif containing B1 isoform a [Homo sapiens]
          Length = 598

 Score =  533 bits (1373), Expect = e-151
 Identities = 270/270 (100%), Positives = 270/270 (100%)

Query: 196 RSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEE 255
           RSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEE
Sbjct: 329 RSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEE 388

Query: 256 KSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQ 315
           KSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQ
Sbjct: 389 KSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQ 448

Query: 316 ELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHRE 375
           ELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHRE
Sbjct: 449 ELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHRE 508

Query: 376 ALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKL 435
           ALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKL
Sbjct: 509 ALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKL 568

Query: 436 GEESGDEIDVPKDELSIELENLFIGGTKPP 465
           GEESGDEIDVPKDELSIELENLFIGGTKPP
Sbjct: 569 GEESGDEIDVPKDELSIELENLFIGGTKPP 598



 Score =  401 bits (1030), Expect = e-112
 Identities = 235/427 (55%), Positives = 285/427 (66%), Gaps = 61/427 (14%)

Query: 1   MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ 60
           MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ
Sbjct: 1   MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ 60

Query: 61  YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR 120
           YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR
Sbjct: 61  YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR 120

Query: 121 QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI 180
           QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI
Sbjct: 121 QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI 180

Query: 181 GSAVMMMLQNILQIN-------------------------------RSKRSKMLLEINRQ 209
           GSAVMMMLQNILQIN                               RS  +K+LL +   
Sbjct: 181 GSAVMMMLQNILQINSGDLLRIGRKALYSILDEVIFKLFSTPSPVIRSTATKLLLLMAES 240

Query: 210 KEEEDLKL----------QLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSAL 259
            +E  + L          +L  +++     S+EL+  ++ ++ P   ++   +   ++A 
Sbjct: 241 HQEILILLRQSTCYKGLRRLLSKQETGTEFSQELR-QLVGLLSPMVYQEVEEQKLHQAAC 299

Query: 260 IIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTD 319
           +IQ +W+G++ RK   +         A + LQR+      + ++ K L    R  +E   
Sbjct: 300 LIQAYWKGFQTRKRLKKLP------SAVIALQRS-----FRSKRSKMLLEINRQKEEEDL 348

Query: 320 ARRVELKKRVDDYVRRHLGSPMSDVVS--------RELHAQAQERLQHYFMGRALEERAQ 371
             +++L+++    + R L   M ++V         RE+  ++   +Q ++ G    +   
Sbjct: 349 KLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFH 408

Query: 372 QHREALI 378
           Q R++LI
Sbjct: 409 QQRQSLI 415


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
           sapiens]
          Length = 1293

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 51/206 (24%), Positives = 91/206 (44%), Gaps = 19/206 (9%)

Query: 188 LQNILQINRSKRSKML-----LEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSML---- 238
           L+ + Q+ ++K +K+       E+  ++EEE+ K Q +L+RQ+   L R+ +        
Sbjct: 717 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 776

Query: 239 -EIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKF 297
            E+    Q E   R+ E++ AL      R  RE +   QQ ++L   +     +    K 
Sbjct: 777 EELARRKQEEALRRQREQEIAL------RRQREEEERQQQEEALRRLEERRREEEERRKQ 830

Query: 298 LAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERL 357
               RK+++  A W   +E    R  E + R+++   R L     +   +EL  Q Q+ L
Sbjct: 831 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR-LRHEEEERKRKELEVQRQKEL 889

Query: 358 --QHYFMGRALEERAQQHREALIAQI 381
             Q      AL    QQ ++  +AQ+
Sbjct: 890 MRQRQQQQEALRRLQQQQQQQQLAQM 915


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
           sapiens]
          Length = 1320

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 51/206 (24%), Positives = 91/206 (44%), Gaps = 19/206 (9%)

Query: 188 LQNILQINRSKRSKML-----LEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSML---- 238
           L+ + Q+ ++K +K+       E+  ++EEE+ K Q +L+RQ+   L R+ +        
Sbjct: 744 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 803

Query: 239 -EIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKF 297
            E+    Q E   R+ E++ AL      R  RE +   QQ ++L   +     +    K 
Sbjct: 804 EELARRKQEEALRRQREQEIAL------RRQREEEERQQQEEALRRLEERRREEEERRKQ 857

Query: 298 LAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERL 357
               RK+++  A W   +E    R  E + R+++   R L     +   +EL  Q Q+ L
Sbjct: 858 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR-LRHEEEERKRKELEVQRQKEL 916

Query: 358 --QHYFMGRALEERAQQHREALIAQI 381
             Q      AL    QQ ++  +AQ+
Sbjct: 917 MRQRQQQQEALRRLQQQQQQQQLAQM 942


>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 51/206 (24%), Positives = 91/206 (44%), Gaps = 19/206 (9%)

Query: 188 LQNILQINRSKRSKML-----LEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSML---- 238
           L+ + Q+ ++K +K+       E+  ++EEE+ K Q +L+RQ+   L R+ +        
Sbjct: 723 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 782

Query: 239 -EIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKF 297
            E+    Q E   R+ E++ AL      R  RE +   QQ ++L   +     +    K 
Sbjct: 783 EELARRKQEEALRRQREQEIAL------RRQREEEERQQQEEALRRLEERRREEEERRKQ 836

Query: 298 LAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERL 357
               RK+++  A W   +E    R  E + R+++   R L     +   +EL  Q Q+ L
Sbjct: 837 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR-LRHEEEERKRKELEVQRQKEL 895

Query: 358 --QHYFMGRALEERAQQHREALIAQI 381
             Q      AL    QQ ++  +AQ+
Sbjct: 896 MRQRQQQQEALRRLQQQQQQQQLAQM 921


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 51/206 (24%), Positives = 91/206 (44%), Gaps = 19/206 (9%)

Query: 188 LQNILQINRSKRSKML-----LEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSML---- 238
           L+ + Q+ ++K +K+       E+  ++EEE+ K Q +L+RQ+   L R+ +        
Sbjct: 723 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 782

Query: 239 -EIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKF 297
            E+    Q E   R+ E++ AL      R  RE +   QQ ++L   +     +    K 
Sbjct: 783 EELARRKQEEALRRQREQEIAL------RRQREEEERQQQEEALRRLEERRREEEERRKQ 836

Query: 298 LAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERL 357
               RK+++  A W   +E    R  E + R+++   R L     +   +EL  Q Q+ L
Sbjct: 837 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR-LRHEEEERKRKELEVQRQKEL 895

Query: 358 --QHYFMGRALEERAQQHREALIAQI 381
             Q      AL    QQ ++  +AQ+
Sbjct: 896 MRQRQQQQEALRRLQQQQQQQQLAQM 921


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 50/252 (19%), Positives = 103/252 (40%), Gaps = 22/252 (8%)

Query: 189 QNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEK 248
           Q + +  + +R + L    + + E+ L+ + QL+R++ +R  ++L+    E  H  + E+
Sbjct: 381 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440

Query: 249 HYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAA--LKFLAKCRKKKK 306
             RE   K     ++ W    E    H+Q +   + K     +R    LK   + R++++
Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ 500

Query: 307 LFAPWRGLQELTDARRVELKK-----------RVDDYVRRHLGSPMSDVVSRELHAQAQE 355
                +  +E  + R   LK+           R +  +RR        ++ RE   + ++
Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ 560

Query: 356 RLQHYFMGRALEERAQQ--------HREALIAQISTNVEQLMKAPSLKEAEGKE-PELFL 406
             +   + R  EER  Q         ++ L  +    +EQ +K   ++  E +E  E  L
Sbjct: 561 ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620

Query: 407 SRSRPVAAKAKQ 418
            R  P   + +Q
Sbjct: 621 KREEPEEERRQQ 632



 Score = 36.6 bits (83), Expect = 0.050
 Identities = 49/229 (21%), Positives = 97/229 (42%), Gaps = 12/229 (5%)

Query: 196 RSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEE 255
           +S++ + L + +RQ+ +E+L  Q Q  ++R  R + E QL   +     + E+   E + 
Sbjct: 154 QSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCK---GHETEEFPDEEQL 210

Query: 256 KSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAP--WRG 313
           +   +++   +G  E++   ++RQ  +  +      R     L K  +K +   P   R 
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270

Query: 314 LQE----LTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEER 369
           LQE    L    R EL++   +  ++         + R+   Q +ER +     R  +ER
Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK---QEEERREQQEERREQQER 327

Query: 370 AQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQ 418
            +Q  E    Q+    E+  +    +E E +  E  L R +    + +Q
Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQ 376



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 52/217 (23%), Positives = 91/217 (41%), Gaps = 39/217 (17%)

Query: 209  QKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGY 268
            Q+EEE+L+ +   +R++  R  +E Q    E +   Q E+     EE+     Q+  R Y
Sbjct: 907  QEEEEELQRE---EREKRRRQEQERQYREEEQL---QQEEEQLLREEREKRRRQERERQY 960

Query: 269  RERKNFHQQRQSLI--------------EYKAAVTLQRAALKFLAKCRKKKKLFAPWRGL 314
            R+ K   Q+ + L+              +Y+    LQ+   + L + R+K++     R  
Sbjct: 961  RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR-----RQE 1015

Query: 315  QELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHR 374
             E    ++ EL++  +  +R            RE   + QER + Y   R  EE  Q+  
Sbjct: 1016 WERQYRKKDELQQEEEQLLRE----------ERE-KRRLQERERQY---REEEELQQEEE 1061

Query: 375  EALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRP 411
            + L  +  T   Q ++    KE E ++ E  L R  P
Sbjct: 1062 QLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098



 Score = 33.1 bits (74), Expect = 0.55
 Identities = 52/249 (20%), Positives = 104/249 (41%), Gaps = 36/249 (14%)

Query: 168  HFLHLLQADNVQIGSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQ----- 222
            H L+   A   Q+     ++ +   ++ R +R K      RQ++E   + + QLQ     
Sbjct: 887  HTLYAKPALQEQLRKEQQLLQEEEEELQREEREKR----RRQEQERQYREEEQLQQEEEQ 942

Query: 223  -------------RQRAMRLSRELQLSMLEIV-------HPGQVEKHYREMEEKSALIIQ 262
                         R+R  R  ++LQ    +++          + EK YRE EE    + Q
Sbjct: 943  LLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEE----LQQ 998

Query: 263  KHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARR 322
            +  +  RE +   ++++   +Y+    LQ+   + L + R+K++L    R  +E  + ++
Sbjct: 999  EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQ 1058

Query: 323  VELKKRVDD-YVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQI 381
             E +   ++   RR            EL  + ++ L+     R  +ER +Q RE    ++
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREE--EEL 1116

Query: 382  STNVEQLMK 390
                EQL++
Sbjct: 1117 QQEEEQLLR 1125



 Score = 30.8 bits (68), Expect = 2.7
 Identities = 50/225 (22%), Positives = 91/225 (40%), Gaps = 41/225 (18%)

Query: 189  QNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEK 248
            + +L+  R KR +   E  RQ  ++D   Q + Q  R  R  R LQ          + E+
Sbjct: 1001 EQLLREEREKRRRQ--EWERQYRKKDELQQEEEQLLREEREKRRLQ----------ERER 1048

Query: 249  HYRE-----MEEKSALIIQKHW-------RGYRERKNFHQQRQSLIEYKAAVTLQRAALK 296
             YRE      EE+  L  ++         R YR+ +   Q+ + L+  +     +R   +
Sbjct: 1049 QYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPE---KRRRQE 1105

Query: 297  FLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQER 356
               +CR++++L       QE     R E +KR    + R            E+  + ++ 
Sbjct: 1106 RERQCREEEEL------QQEEEQLLREEREKRRRQELERQYRE------EEEVQQEEEQL 1153

Query: 357  LQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKE 401
            L+     R  +E  +Q+RE    ++    EQL++    K  + +E
Sbjct: 1154 LREEPEKRRRQELERQYREE--EELQQEEEQLLREEQEKRRQERE 1196



 Score = 30.0 bits (66), Expect = 4.7
 Identities = 23/87 (26%), Positives = 40/87 (45%), Gaps = 17/87 (19%)

Query: 193  QINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYRE 252
            Q+ R +R + +LE  + + E +   + QL+RQ   R  RE              E+  R+
Sbjct: 1739 QLRRQERYRKILEEEQLRPERE---EQQLRRQERDRKFRE--------------EEQLRQ 1781

Query: 253  MEEKSALIIQKHWRGYRERKNFHQQRQ 279
              E+  L  Q+  R +RE +   Q+R+
Sbjct: 1782 EREEQQLRSQESDRKFREEEQLRQERE 1808



 Score = 29.6 bits (65), Expect = 6.1
 Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 17/100 (17%)

Query: 193  QINRSKRSKMLLE---INRQKEEEDLKLQ---LQLQRQRAMRLSRELQLSMLEIVHPGQV 246
            Q+ R +R +   E   + +++EE+ L+ Q    + + +  +R  RE Q      + P Q 
Sbjct: 1763 QLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQ-----LRPQQR 1817

Query: 247  EKHYR------EMEEKSALIIQKHWRGYRERKNFHQQRQS 280
            +  YR      ++EE+   + Q+  R YR  + F  Q +S
Sbjct: 1818 DGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKS 1857


>gi|45439327 periplakin [Homo sapiens]
          Length = 1756

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 75/295 (25%), Positives = 118/295 (40%), Gaps = 50/295 (16%)

Query: 187  MLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQV 246
            ++Q ILQ     ++K  +   R K  E+ K Q+ L+R+RA   S+E Q++  E       
Sbjct: 1291 VVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERA---SQEEQIARKE------- 1340

Query: 247  EKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQ----RAALKFLAKCR 302
                 E+      ++Q+    Y E      +  +  E       Q    RA L+ L + R
Sbjct: 1341 ----EELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRR 1396

Query: 303  KKKKLFAPWRGLQELTDAR--RVELKKRVDDYVRRHLGSPMSDVVSRE---------LHA 351
             + +     R L+EL   R  R E ++ V    +R       +  +RE         L  
Sbjct: 1397 TELE-----RQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQ 1451

Query: 352  QAQERLQHYFMGRALEERAQQHREALIAQISTNVEQL-MKAPSLKEAEGKEPELFLSRSR 410
              Q+  +H  +   LEE  +QHR  L   +   +E L  K  +L++AE KE ++ LS S 
Sbjct: 1452 DPQQAREHALLRLQLEE--EQHRRQL---LEGELETLRRKLAALEKAEVKE-KVVLSESV 1505

Query: 411  PVAAKAKQAHLTTLKHIQAPWWKKLGEESGD--EIDVPKDELSIELENLFIGGTK 463
             V     +  +  LK         L EES    E+DV    L   L  L    +K
Sbjct: 1506 QVEKGDTEQEIQRLK-------SSLEEESRSKRELDVEVSRLEARLSELEFHNSK 1553


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 41/167 (24%), Positives = 70/167 (41%), Gaps = 15/167 (8%)

Query: 163  VLQSDHFLHLLQADNVQIGSAVMMMLQNILQINRSKRSKMLLEINRQKEE---EDLKLQL 219
            +L   HFLHL QA  +     +    +N L        K + +   QK+          L
Sbjct: 1033 LLCRQHFLHLRQASVI-----IQRFWRNYLN------QKQVRDAAVQKDAFVMASAAALL 1081

Query: 220  QLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQ 279
            Q   +  +   R L+L    IV   +   +YR     +A+ IQ  W+ YRE K + +QR+
Sbjct: 1082 QASWRAHLERQRYLELRAAAIVIQQKWRDYYRR-RHMAAICIQARWKAYRESKRYQEQRK 1140

Query: 280  SLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELK 326
             +I  ++     RA  +F A   ++ +   P  GL  +     +E++
Sbjct: 1141 KIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLEIQ 1187


>gi|21450705 leucine rich repeat containing 45 [Homo sapiens]
          Length = 670

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 54/214 (25%), Positives = 98/214 (45%), Gaps = 11/214 (5%)

Query: 192 LQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLE---IVHPGQVEK 248
           L+ + S R K +  + R  EE +  +Q ++QR  A RLS E +LS ++   +   GQ E+
Sbjct: 426 LEDSESLRIKEVEHMTRHLEESEKAMQERVQRLEAARLSLEEELSRVKAAALSERGQAEE 485

Query: 249 HYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKK--- 305
              + + ++ L  Q+      ++     Q +   +      LQ+  +   A+ R  +   
Sbjct: 486 ELIKAKSQARLEEQQRLAHLEDKLRLLAQAR---DEAQGACLQQKQVVAEAQTRVSQLGL 542

Query: 306 KLFAPWRGLQELTDARRVELKKRVDDYVRRHLG-SPMSDVVSRELHAQAQERLQHYFMGR 364
           ++    R L+EL     ++ ++RV +  R  +     +  +  EL AQ   R +   + R
Sbjct: 543 QVEGLRRRLEELQQELSLKDQERVAEVSRVRVELQEQNGRLQAELAAQEALREKAAALER 602

Query: 365 ALEERAQQHREALIAQISTNVEQLMKAPSLKEAE 398
            L+  A  HREAL+ + S N   L +   L+EAE
Sbjct: 603 QLKVMASDHREALLDRESENA-SLREKLRLREAE 635



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 50/210 (23%), Positives = 92/210 (43%), Gaps = 32/210 (15%)

Query: 209 QKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGY 268
           Q++ ++LKL+ Q   +R  +L R+L  +                  EK+ L+  ++    
Sbjct: 338 QRQAKELKLEQQEAAERESKLLRDLSAA-----------------NEKNLLL--QNQVDE 378

Query: 269 RERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKR 328
            ERK F  Q++ L + +  +T   A LK  A   +++      R  Q L D+  + +K+ 
Sbjct: 379 LERK-FRCQQEQLFQTRQEMTSMSAELKMRAIQAEERLDMEKRRCRQSLEDSESLRIKE- 436

Query: 329 VDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGR-ALEERAQQHREALIAQISTNVEQ 387
             +++ RHL          E     QER+Q     R +LEE   + + A +++     E+
Sbjct: 437 -VEHMTRHL---------EESEKAMQERVQRLEAARLSLEEELSRVKAAALSERGQAEEE 486

Query: 388 LMKAPSLKEAEGKEPELFLSRSRPVAAKAK 417
           L+KA S    E ++    L     + A+A+
Sbjct: 487 LIKAKSQARLEEQQRLAHLEDKLRLLAQAR 516


>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
           sapiens]
          Length = 551

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 63/274 (22%), Positives = 121/274 (44%), Gaps = 29/274 (10%)

Query: 158 ELIQNVLQSDHFLHLLQADNVQIGSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKL 217
           E  QN+LQ  + L + Q + ++  S +++  +     +     K  ++     EE+ L  
Sbjct: 171 ERAQNLLQRANKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQ 230

Query: 218 QLQLQRQRAMRLSRELQLSMLEIVHPGQ---VEKHYREMEEKSALIIQKHWRGYRERKNF 274
            ++++RQ++++   EL+    E    G+   VE+  +  EE+S L  Q+           
Sbjct: 231 MMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQR----------- 279

Query: 275 HQQRQSLIEYKAAVTLQRAALKFLAKCRKKK-KLFAPWRGLQELTDARRVEL---KKRVD 330
            Q+++ ++EY     LQ   LK + + +++K K+ A  + + +    ++ EL   +K  D
Sbjct: 280 EQEKEQMLEYME--QLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLAD 337

Query: 331 DYVRRHLGSPMSDVVSRELHAQ--AQERLQHYFMGRALEERAQQH---REALIAQISTNV 385
             V       M+     E   +   +E+ +     RA++E+AQ +   ++AL A+ +  V
Sbjct: 338 QMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEV 397

Query: 386 EQLMKAPSLKEAEGK----EPELFLSRSRPVAAK 415
                    KE   K    E EL  SR   VA K
Sbjct: 398 ADREWRRKEKENARKKMETEAELRKSRLEQVAFK 431


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
            sapiens]
          Length = 2168

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 35/186 (18%), Positives = 84/186 (45%), Gaps = 16/186 (8%)

Query: 211  EEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRE 270
            +  D KL  +LQ Q   R  +  Q+ +L  +   +  +  +E +++ A++  +  R  +E
Sbjct: 879  DNADAKLLRKLQAQEIAR--QAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKE 936

Query: 271  RKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVD 330
            +    +Q++ +   +     +    + + + +KKKK        +E  +A+ +E +KR+ 
Sbjct: 937  QIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKK--------EEAANAKLLEAEKRIK 988

Query: 331  DYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMK 390
            +   R   + +        H + + R QH  + +A+E R +   +  + Q   + ++L K
Sbjct: 989  EKEMRRQQAVLLK------HQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNK 1042

Query: 391  APSLKE 396
               L++
Sbjct: 1043 ERKLEQ 1048


>gi|32484977 angiomotin like 2 [Homo sapiens]
          Length = 780

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 65/292 (22%), Positives = 113/292 (38%), Gaps = 42/292 (14%)

Query: 174 QADNVQIGSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSR-E 232
           QA +   GSA +  ++ +L+ N             Q++ E L+ +L+   ++A R+ + E
Sbjct: 300 QASSATSGSAHLAQMEAVLRENA----------RLQRDNERLQRELESSAEKAGRIEKLE 349

Query: 233 LQLSMLEIVHPG---------QVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIE 283
            ++  L   H            +EK  R   +     +Q   R  RER     +R +   
Sbjct: 350 SEIQRLSEAHESLTRASSKREALEKTMRNKMDSEMRRLQDFNRDLRERLESANRRLASKT 409

Query: 284 YKAAVTLQRAALKFLAKC-------RKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRH 336
            +A    Q    K LA+         K ++  A  RG  E    RR EL ++     +  
Sbjct: 410 QEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIE-DQRRRAELLEQALGNAQGR 468

Query: 337 LGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMK------ 390
                 ++  ++ + +  ERLQ   +G+   + A + RE L  ++ T +EQ +K      
Sbjct: 469 AARAEEELRKKQAYVEKVERLQQA-LGQL--QAACEKREQLELRLRTRLEQELKALRAQQ 525

Query: 391 ----APSLKEAEGKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEE 438
               AP      G  PEL   R      + K+  +  L+     W +K  EE
Sbjct: 526 RQAGAPGGSSGSGGSPELSALRLSE-QLREKEEQILALEADMTKWEQKYLEE 576


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 50/226 (22%), Positives = 94/226 (41%), Gaps = 45/226 (19%)

Query: 202 MLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALII 261
           MLLE+ R K   D  + LQ   +     S  L+L                   + +A +I
Sbjct: 734 MLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL-------------------KNAATLI 774

Query: 262 QKHWRGYRERKNF-------------HQQRQSLIEYKAAVTLQRAALKFLAKCR----KK 304
           Q+HWRG+  RKN+             H+ R+   +Y+ A   ++  ++F A+CR    +K
Sbjct: 775 QRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLA---RQRIIQFQARCRAYLVRK 831

Query: 305 KKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGR 364
                 W  L     AR + + +R+   +R      +  + + ++    +E+L+     +
Sbjct: 832 AFRHRLWAVLTVQAYARGM-IARRLHQRLRAEY---LWRLEAEKMRLAEEEKLRKEMSAK 887

Query: 365 ALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSR 410
             +E A++  +  +AQ++   E   +    KEA  ++ EL     R
Sbjct: 888 KAKEEAERKHQERLAQLAR--EDAERELKEKEAARRKKELLEQMER 931


>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
          Length = 1204

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 50/226 (22%), Positives = 94/226 (41%), Gaps = 45/226 (19%)

Query: 202 MLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALII 261
           MLLE+ R K   D  + LQ   +     S  L+L                   + +A +I
Sbjct: 734 MLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL-------------------KNAATLI 774

Query: 262 QKHWRGYRERKNF-------------HQQRQSLIEYKAAVTLQRAALKFLAKCR----KK 304
           Q+HWRG+  RKN+             H+ R+   +Y+ A   ++  ++F A+CR    +K
Sbjct: 775 QRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLA---RQRIIQFQARCRAYLVRK 831

Query: 305 KKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGR 364
                 W  L     AR + + +R+   +R      +  + + ++    +E+L+     +
Sbjct: 832 AFRHRLWAVLTVQAYARGM-IARRLHQRLRAEY---LWRLEAEKMRLAEEEKLRKEMSAK 887

Query: 365 ALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSR 410
             +E A++  +  +AQ++   E   +    KEA  ++ EL     R
Sbjct: 888 KAKEEAERKHQERLAQLAR--EDAERELKEKEAARRKKELLEQMER 931


>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
          Length = 2215

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 50/226 (22%), Positives = 94/226 (41%), Gaps = 45/226 (19%)

Query: 202 MLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALII 261
           MLLE+ R K   D  + LQ   +     S  L+L                   + +A +I
Sbjct: 734 MLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL-------------------KNAATLI 774

Query: 262 QKHWRGYRERKNF-------------HQQRQSLIEYKAAVTLQRAALKFLAKCR----KK 304
           Q+HWRG+  RKN+             H+ R+   +Y+ A   ++  ++F A+CR    +K
Sbjct: 775 QRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLA---RQRIIQFQARCRAYLVRK 831

Query: 305 KKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGR 364
                 W  L     AR + + +R+   +R      +  + + ++    +E+L+     +
Sbjct: 832 AFRHRLWAVLTVQAYARGM-IARRLHQRLRAEY---LWRLEAEKMRLAEEEKLRKEMSAK 887

Query: 365 ALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSR 410
             +E A++  +  +AQ++   E   +    KEA  ++ EL     R
Sbjct: 888 KAKEEAERKHQERLAQLAR--EDAERELKEKEAARRKKELLEQMER 931


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 50/221 (22%), Positives = 94/221 (42%), Gaps = 12/221 (5%)

Query: 188 LQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVE 247
           L+ +LQ  R +  +M  E  +Q E++  ++  + ++ +  RL+ E            +VE
Sbjct: 578 LRKVLQA-RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 636

Query: 248 KHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAA-LKFLAKCRKKKK 306
              ++ EE   L     W    E +  HQ+     + +    L++AA  K LA+ R++++
Sbjct: 637 ARRKQEEEARRL----RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER 692

Query: 307 LFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQE---RLQHYFMG 363
                R  +     RR + ++  +  +         + +  E   Q +E   RLQ   + 
Sbjct: 693 REQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ 752

Query: 364 RALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPEL 404
           R LEE+ ++  +  +A+     EQ  KA   KEA G    L
Sbjct: 753 RELEEKKKKEEQQRLAERQLQEEQEKKA---KEAAGASKAL 790



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 44/240 (18%), Positives = 105/240 (43%), Gaps = 13/240 (5%)

Query: 193 QINRSKRSKMLLEINRQKEEEDLKLQLQ-LQRQRAMRLSRELQ----LSMLEIVHPGQVE 247
           ++   +R +   ++ RQK EED + +L+ ++ +R  RL + LQ    +  ++     Q+E
Sbjct: 541 RLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIE 600

Query: 248 KHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKK--- 304
           + + +++EK+    ++     + +K    ++   +E +     +   L++L +  ++   
Sbjct: 601 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 660

Query: 305 -----KKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQH 359
                KK       L++  +A+R+  ++  +   +        +   RE   + QER   
Sbjct: 661 QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLA 720

Query: 360 YFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQA 419
               R  +ER Q  RE    + +  +++      L+E + KE +  L+  +    + K+A
Sbjct: 721 EQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 780


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 50/221 (22%), Positives = 94/221 (42%), Gaps = 12/221 (5%)

Query: 188 LQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVE 247
           L+ +LQ  R +  +M  E  +Q E++  ++  + ++ +  RL+ E            +VE
Sbjct: 574 LRKVLQA-RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 632

Query: 248 KHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAA-LKFLAKCRKKKK 306
              ++ EE   L     W    E +  HQ+     + +    L++AA  K LA+ R++++
Sbjct: 633 ARRKQEEEARRL----RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER 688

Query: 307 LFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQE---RLQHYFMG 363
                R  +     RR + ++  +  +         + +  E   Q +E   RLQ   + 
Sbjct: 689 REQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ 748

Query: 364 RALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPEL 404
           R LEE+ ++  +  +A+     EQ  KA   KEA G    L
Sbjct: 749 RELEEKKKKEEQQRLAERQLQEEQEKKA---KEAAGASKAL 786



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 44/240 (18%), Positives = 105/240 (43%), Gaps = 13/240 (5%)

Query: 193 QINRSKRSKMLLEINRQKEEEDLKLQLQ-LQRQRAMRLSRELQ----LSMLEIVHPGQVE 247
           ++   +R +   ++ RQK EED + +L+ ++ +R  RL + LQ    +  ++     Q+E
Sbjct: 537 RLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIE 596

Query: 248 KHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKK--- 304
           + + +++EK+    ++     + +K    ++   +E +     +   L++L +  ++   
Sbjct: 597 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 656

Query: 305 -----KKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQH 359
                KK       L++  +A+R+  ++  +   +        +   RE   + QER   
Sbjct: 657 QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLA 716

Query: 360 YFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQA 419
               R  +ER Q  RE    + +  +++      L+E + KE +  L+  +    + K+A
Sbjct: 717 EQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 776


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 60/254 (23%), Positives = 103/254 (40%), Gaps = 30/254 (11%)

Query: 205  EINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKH 264
            E +RQ + E  +LQ  +Q   A   + E     L++      E   ++ EE   L+  ++
Sbjct: 961  ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQL-EKVTTEAKMKKFEEDLLLLEDQN 1019

Query: 265  WRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVE 324
             +  +ERK    +   L E+ +    +   +K L K R K +       + ++ D  R E
Sbjct: 1020 SKLSKERKLLEDR---LAEFSSQAAEEEEKVKSLNKLRLKYEAT-----IADMEDRLRKE 1071

Query: 325  LKKRVD-DYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQIST 383
             K R + + ++R L     D  S EL  Q  E+              QQ  E L AQ+  
Sbjct: 1072 EKGRQELEKLKRRL-----DGESSELQEQMVEQ--------------QQRAEELRAQLGR 1112

Query: 384  NVEQLMKAPSLKEAE-GKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESGDE 442
              E+L  A +  E E G   +L  S     AA A+       + +     +K   + G+E
Sbjct: 1113 KEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE 1172

Query: 443  IDVPKDELSIELEN 456
            ++  + EL   L++
Sbjct: 1173 LEALRGELEDTLDS 1186


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 60/254 (23%), Positives = 103/254 (40%), Gaps = 30/254 (11%)

Query: 205  EINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKH 264
            E +RQ + E  +LQ  +Q   A   + E     L++      E   ++ EE   L+  ++
Sbjct: 953  ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQL-EKVTTEAKMKKFEEDLLLLEDQN 1011

Query: 265  WRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVE 324
             +  +ERK    +   L E+ +    +   +K L K R K +       + ++ D  R E
Sbjct: 1012 SKLSKERKLLEDR---LAEFSSQAAEEEEKVKSLNKLRLKYEAT-----IADMEDRLRKE 1063

Query: 325  LKKRVD-DYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQIST 383
             K R + + ++R L     D  S EL  Q  E+              QQ  E L AQ+  
Sbjct: 1064 EKGRQELEKLKRRL-----DGESSELQEQMVEQ--------------QQRAEELRAQLGR 1104

Query: 384  NVEQLMKAPSLKEAE-GKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESGDE 442
              E+L  A +  E E G   +L  S     AA A+       + +     +K   + G+E
Sbjct: 1105 KEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE 1164

Query: 443  IDVPKDELSIELEN 456
            ++  + EL   L++
Sbjct: 1165 LEALRGELEDTLDS 1178


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 60/254 (23%), Positives = 103/254 (40%), Gaps = 30/254 (11%)

Query: 205  EINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKH 264
            E +RQ + E  +LQ  +Q   A   + E     L++      E   ++ EE   L+  ++
Sbjct: 994  ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQL-EKVTTEAKMKKFEEDLLLLEDQN 1052

Query: 265  WRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVE 324
             +  +ERK    +   L E+ +    +   +K L K R K +       + ++ D  R E
Sbjct: 1053 SKLSKERKLLEDR---LAEFSSQAAEEEEKVKSLNKLRLKYEAT-----IADMEDRLRKE 1104

Query: 325  LKKRVD-DYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQIST 383
             K R + + ++R L     D  S EL  Q  E+              QQ  E L AQ+  
Sbjct: 1105 EKGRQELEKLKRRL-----DGESSELQEQMVEQ--------------QQRAEELRAQLGR 1145

Query: 384  NVEQLMKAPSLKEAE-GKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESGDE 442
              E+L  A +  E E G   +L  S     AA A+       + +     +K   + G+E
Sbjct: 1146 KEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE 1205

Query: 443  IDVPKDELSIELEN 456
            ++  + EL   L++
Sbjct: 1206 LEALRGELEDTLDS 1219


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 50/230 (21%), Positives = 99/230 (43%), Gaps = 20/230 (8%)

Query: 192 LQINRSKRSKMLLEINRQKEEEDLKLQ-LQLQRQRAMRLSRELQLSMLEIVHPGQVEKHY 250
           L I   +  K L   N++ ++ + +LQ L+++ Q   +   EL++S   +    Q+EK  
Sbjct: 761 LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE---QLEKEN 817

Query: 251 REMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAP 310
           + +E++++ + +   +  +E K   QQ +         TL+   +K +    K+ K  + 
Sbjct: 818 KSLEQETSQLEKDKKQLEKENKRLRQQAEI-----KDTTLEENNVK-IGNLEKENKTLSK 871

Query: 311 WRGLQELTDARRVELKKRVDDYVRR------HLGSPMSDVVSRELHAQAQ----ERLQHY 360
             G+ + +  R  EL+K   + V+R       L +   D+VS +L  Q      E+L H 
Sbjct: 872 EIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHE 931

Query: 361 FMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSR 410
                L +    H E         +E  +++   K  E KE ++    +R
Sbjct: 932 LEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEAR 981


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 50/248 (20%), Positives = 114/248 (45%), Gaps = 40/248 (16%)

Query: 209  QKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHY---REMEEKSALIIQKHW 265
            +K+E +L+ +L+ Q  R M L   +    +EI    +V K+Y   +++E K  +   +H+
Sbjct: 1510 EKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHF 1569

Query: 266  RGYRERKN--FHQQRQSLIEYKAAVTLQRAALKF---------LAKCRKKKKLFAPWRGL 314
            +   E K+    +  + ++  +  V   +A L+          L+   K+++L A    L
Sbjct: 1570 QELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRL 1629

Query: 315  QELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHR 374
            +  + A+  ELK++ +  +           + ++L +Q +E+          EE+ ++  
Sbjct: 1630 ESESAAKLAELKRKAEQKIA---------AIKKQLLSQMEEK----------EEQYKKGT 1670

Query: 375  EALIAQISTNVEQLMK-----APSLKEAEGKEPE-LFLSRS-RPVAAKAKQAHLTTLKHI 427
            E+ +++++T +++  +        LK  E  + E L + RS + VAA  +Q    +   +
Sbjct: 1671 ESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCV 1730

Query: 428  QAPWWKKL 435
            Q  + +K+
Sbjct: 1731 QKTYEEKI 1738



 Score = 30.8 bits (68), Expect = 2.7
 Identities = 57/272 (20%), Positives = 113/272 (41%), Gaps = 29/272 (10%)

Query: 190  NILQINRSKRSKMLLEINRQKEE---EDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQV 246
            ++LQ N +++ K+L  + ++KEE      +++ Q Q +R ++L         +    G +
Sbjct: 1739 SVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQ-ERLIKLEHAEAKQHEDQSMIGHL 1797

Query: 247  EKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSL--IEYKAAVTLQRAALKFLAKCRKK 304
            ++   E  +K +LI+ +H      + N  Q +Q+L  +      TLQ   L      +K 
Sbjct: 1798 QEELEEKNKKYSLIVAQHVEKEGGKNNI-QAKQNLENVFDDVQKTLQEKELTCQILEQKI 1856

Query: 305  KKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMS--DVVSRELHAQAQERLQ-HYF 361
            K+L +    L    +  RVE+++    Y +      M   +  +  L    +E+ + H  
Sbjct: 1857 KELDS---CLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLV 1913

Query: 362  MGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHL 421
              + L     QH +           +L  A   K+  GKE  + L +   +  K  Q  L
Sbjct: 1914 QPKLLSNMEAQHNDLEF--------KLAGAEREKQKLGKE-IVRLQKDLRMLRKEHQQEL 1964

Query: 422  TTLKHIQAPWWKKLGEESGDEIDVPKDELSIE 453
              LK       K+  +E  ++I   +++L ++
Sbjct: 1965 EILK-------KEYDQEREEKIKQEQEDLELK 1989


>gi|70980531 GGA binding partner [Homo sapiens]
          Length = 441

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 51/235 (21%), Positives = 111/235 (47%), Gaps = 35/235 (14%)

Query: 206 INRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHW 265
           I  Q++   L+++L++  +   R+ ++++ S++E      +EK + + +E+ A+  Q  +
Sbjct: 132 IQLQQKISSLEIKLKVSEEEKQRIKQDVE-SLME--KHNVLEKGFLKEKEQEAISFQDRY 188

Query: 266 RGYRE---------RKNFHQQRQSLI-EYKAAVTLQRAALKFLAKCRKKKKLFAPWRGL- 314
           +  +E         RK  H+    ++ EYKA   L ++++K   +  +K+ + A  +   
Sbjct: 189 KELQEKHKQELEDMRKAGHEALSIIVDEYKA---LLQSSVKQQVEAIEKQYISAIEKQAH 245

Query: 315 --QELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQ 372
             +EL +A+   L + +D    + L   + + +   L  Q+QE  Q   + + LEE  Q+
Sbjct: 246 KCEELLNAQHQRLLEMLD--TEKEL---LKEKIKEALIQQSQE--QKEILEKCLEEERQR 298

Query: 373 HREALIAQISTNVEQLMKA---------PSLKEAEGKEPELFLSRSRPVAAKAKQ 418
           ++EAL++      E +  A          +L++A  +E EL+ +       K  Q
Sbjct: 299 NKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQEKVSQ 353


>gi|28372509 Ymer protein short isoform [Homo sapiens]
          Length = 306

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 64/292 (21%), Positives = 109/292 (37%), Gaps = 67/292 (22%)

Query: 163 VLQSDHFLHLLQADNVQIGSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQ 222
           VL+     H LQ   ++   A  +    ++Q +        L++ +Q +EEDLK Q QLQ
Sbjct: 23  VLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHD--------LQVAKQLQEEDLKAQAQLQ 74

Query: 223 RQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLI 282
                                    K Y+++E++   I Q+     +E+     +R+ + 
Sbjct: 75  -------------------------KRYKDLEQQDCEIAQE----IQEKLAIEAERRRIQ 105

Query: 283 EYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVE---LKKRVDDYVRRHLGS 339
           E K     +    K L + +K+KK F  +   +   D+   E   +K RV          
Sbjct: 106 EKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRV---------- 155

Query: 340 PMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEG 399
            M + VS    ++   R Q ++   A   R  Q  E L  Q+     Q+ +   +     
Sbjct: 156 -MKEAVSTP--SRMAHRDQEWY--DAEIARKLQEEELLATQVDMRAAQVAQDEEI----- 205

Query: 400 KEPELFLSRSRPVAAKAKQAHLTTL-KHIQAPWWK----KLGEESGDEIDVP 446
               L ++  +    KAK+   ++L K  Q P WK    K       E D P
Sbjct: 206 --ARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEP 255


>gi|126116596 asp (abnormal spindle)-like, microcephaly associated
            [Homo sapiens]
          Length = 3477

 Score = 37.4 bits (85), Expect = 0.029
 Identities = 38/155 (24%), Positives = 72/155 (46%), Gaps = 16/155 (10%)

Query: 257  SALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQ---------RAALKFLAKCRKKKKL 307
            S + IQ ++R Y  +K F   + + I+ ++ V ++         RAA  F+ +C + KK+
Sbjct: 1658 SVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKI 1717

Query: 308  FAPWRGLQELTDARR--VELKKRVDDY-VRRHLGSPMSDVVSRELHAQAQERLQHYFMGR 364
             A  R  +E    R   ++L+  V  Y VR+ +      V+S + + + ++  Q+Y    
Sbjct: 1718 AAQKR--EEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMY 1775

Query: 365  ALEERAQQHREALIAQIS--TNVEQLMKAPSLKEA 397
                  Q +  A  AQ++   N  Q+ KA +  +A
Sbjct: 1776 KAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQA 1810



 Score = 32.7 bits (73), Expect = 0.72
 Identities = 29/136 (21%), Positives = 66/136 (48%), Gaps = 9/136 (6%)

Query: 189  QNILQINRSKRSKMLLEINR----QKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPG 244
            ++IL I +  ++ +  +I R    QK    ++LQ   +R +A  L R+++ + +   +  
Sbjct: 1512 ESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWR 1571

Query: 245  QVEKHYREMEEKSALI-IQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRK 303
              +   R +  K  +I  Q H R +++R+ + + +++ +  +        A+K LA  +K
Sbjct: 1572 MRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQK 1631

Query: 304  KKK----LFAPWRGLQ 315
             +     L + +RG+Q
Sbjct: 1632 TRSAVIVLQSAYRGMQ 1647



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 41/220 (18%), Positives = 93/220 (42%), Gaps = 37/220 (16%)

Query: 191  ILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQ----- 245
            +L + +  R+  L++   +K +    L+   +R++A R+   +QL+++  +   +     
Sbjct: 1260 LLDLRKEIRAARLIQTTWRKYKLKTDLKRHQEREKAARI---IQLAVINFLAKQRLRKRV 1316

Query: 246  -----VEKHYR-----------------EMEEKSALIIQKHWRGYRERKNFHQQRQSLIE 283
                 ++K++R                 +++ K+A +IQ +WR Y  R+ F + +   I 
Sbjct: 1317 NAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSII 1376

Query: 284  YKAAVTLQRAALKFLAKCRKKKKLFAPWRG-LQELTDARRVELKKRVDDYVRRHLGSPMS 342
             ++ + +  A   +         +   WR  L+   D +R E+ K     ++    S   
Sbjct: 1377 LQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQ----SMFR 1432

Query: 343  DVVSRELHAQAQER--LQHYFMGRALEERAQQHREALIAQ 380
                R++ +Q +    LQ  F    L ++A++   A+I Q
Sbjct: 1433 KWKQRKMQSQVKATVILQRAFREWHLRKQAKEENSAIIIQ 1472



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 4/103 (3%)

Query: 224  QRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIE 283
            QR   L  +   + L+  + G   +   + +  +AL IQ  +RGY +R  +    QS+I+
Sbjct: 1794 QRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIK 1853

Query: 284  ----YKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARR 322
                Y+A  TL      FL        L + +RG +     RR
Sbjct: 1854 IQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRR 1896



 Score = 30.8 bits (68), Expect = 2.7
 Identities = 25/90 (27%), Positives = 49/90 (54%), Gaps = 11/90 (12%)

Query: 217  LQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQ 276
            L+ QLQRQ    +       +++  +   V++   ++ +K+AL+IQK++R Y   +   +
Sbjct: 1963 LRRQLQRQHKCAI-------IIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGR---E 2012

Query: 277  QRQSLIEYKAAVTLQRAALKFLAKCRKKKK 306
            Q    ++ KAAV   ++A + + K RK+ K
Sbjct: 2013 QNHLYLKTKAAVVTLQSAYRGM-KVRKRIK 2041



 Score = 30.0 bits (66), Expect = 4.7
 Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 6/95 (6%)

Query: 218  QLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQ 277
            Q  L R+ A+ L    + + L   H  QV    R     S +IIQ   +G+ +++ F + 
Sbjct: 2878 QFLLYRKAAVVLQNHYR-AFLSAKHQRQVYLQIRS----SVIIIQARSKGFIQKRKFQEI 2932

Query: 278  RQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWR 312
            + S I+ +A     RA  K+L K +   K+ A +R
Sbjct: 2933 KNSTIKIQAMWRRYRAK-KYLCKVKAACKIQAWYR 2966



 Score = 29.3 bits (64), Expect = 7.9
 Identities = 22/121 (18%), Positives = 56/121 (46%), Gaps = 12/121 (9%)

Query: 189  QNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLE--IVHPG-- 244
            Q + Q N  K+      +    ++ ++K Q+Q Q Q A+ + +  +   +    +H    
Sbjct: 2594 QKVFQHNELKKETC---VQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRAT 2650

Query: 245  --QVEKHYREM---EEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLA 299
               +++ YR++     ++ + IQ ++RG++ RK+     ++    ++   + RA + +  
Sbjct: 2651 VVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYET 2710

Query: 300  K 300
            K
Sbjct: 2711 K 2711


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
            sapiens]
          Length = 1843

 Score = 37.4 bits (85), Expect = 0.029
 Identities = 56/255 (21%), Positives = 109/255 (42%), Gaps = 26/255 (10%)

Query: 192  LQINRSKRSKMLLEINRQKEEEDLKLQ-LQLQRQRAMRLSRELQLSMLEIVHPGQVEKHY 250
            L I   +  K L   N++ ++ + +LQ L+++ Q   +   EL++S   +    Q+EK  
Sbjct: 761  LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE---QLEKEN 817

Query: 251  REMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAP 310
            + +E++++ + +   +  +E K   QQ +         TL+   +K +    K+ K  + 
Sbjct: 818  KSLEQETSQLEKDKKQLEKENKRLRQQAEI-----KDTTLEENNVK-IGNLEKENKTLSK 871

Query: 311  WRGLQELTDARRVELKKRVDDYVRR------HLGSPMSDVVSRELHAQAQ----ERLQHY 360
              G+ + +  R  EL+K   + V+R       L +   D+VS +L  Q      E+L H 
Sbjct: 872  EIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHE 931

Query: 361  FMGRALEERAQQHRE-----ALIAQISTNVEQ-LMKAPSLKEAEGKEPELFLSRSRPVAA 414
                 L +    H E     +    + + +E  L K+  +KE +    E  L  S     
Sbjct: 932  LEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQ 991

Query: 415  KAKQAHLTTLKHIQA 429
            + +Q   T  K+ +A
Sbjct: 992  QLRQELKTVKKNYEA 1006


>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
          Length = 715

 Score = 37.0 bits (84), Expect = 0.038
 Identities = 52/239 (21%), Positives = 102/239 (42%), Gaps = 31/239 (12%)

Query: 74  QGGWTTISQLTQILSHCCVGLEPGEDAEEFYN-ELLPSAAENFLVLGRQL----QTCFIN 128
           Q G +T+S  +Q+ +    G   G+ + E    ELL    +  L   RQL    QT  + 
Sbjct: 17  QNGMSTLS--SQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLK 74

Query: 129 AAKAEEKDELLHF---FQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQIGSAVM 185
           + K+ +K   L       ++T  +         L Q VL       LLQ        AVM
Sbjct: 75  SPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQ-----AVM 129

Query: 186 MMLQNILQINRSKRSKMLLEI------NRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLE 239
           +  Q + +  + ++ ++ L++       +Q++++  + Q Q Q+Q+  +  ++ Q    +
Sbjct: 130 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 189

Query: 240 IVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQ---QRQSLIEYKAAVTLQRAAL 295
             HPG+  K  ++ +++   +         ++  F Q   Q Q L + +  ++LQR  L
Sbjct: 190 QQHPGKQAKEQQQQQQQQQQLA-------AQQLVFQQQLLQMQQLQQQQHLLSLQRQGL 241



 Score = 30.0 bits (66), Expect = 4.7
 Identities = 34/208 (16%), Positives = 92/208 (44%), Gaps = 25/208 (12%)

Query: 191 ILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHY 250
           +L + + +  +   ++  Q++   LK      +QR +++   + +   +++ P Q+++  
Sbjct: 49  LLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQ-- 106

Query: 251 REMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAP 310
                    I+Q+            QQ Q+L++ + AV LQ+  L+   K +++++L   
Sbjct: 107 ---------ILQQQVLS-------PQQLQALLQQQQAVMLQQQQLQEFYK-KQQEQLHL- 148

Query: 311 WRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERA 370
                +L   ++ + +++     ++           ++   Q Q++ QH       +++ 
Sbjct: 149 -----QLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 203

Query: 371 QQHREALIAQISTNVEQLMKAPSLKEAE 398
           QQ ++ L AQ     +QL++   L++ +
Sbjct: 204 QQQQQQLAAQQLVFQQQLLQMQQLQQQQ 231


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 37.0 bits (84), Expect = 0.038
 Identities = 42/151 (27%), Positives = 72/151 (47%), Gaps = 15/151 (9%)

Query: 319  DARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALI 378
            D+   +L  RV+D   + LG+ M   + +EL A+A+E  +     RA   R ++ R    
Sbjct: 1133 DSELSQLSLRVED--EQLLGAQMQKKI-KELQARAEELEEELEAERAARARVEKQRAEAA 1189

Query: 379  AQISTNVEQLMKA--PSLKEAEG---KEPEL-FLSRSRPVAAKAKQAHLTTLKHIQAPWW 432
             ++    E+L +A   S  + EG   +E EL  L R    AA   +A +  L+  QA   
Sbjct: 1190 RELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGA 1249

Query: 433  KKLGEESG------DEIDVPKDELSIELENL 457
             +LGE+         +++  K EL +E+++L
Sbjct: 1250 AELGEQVDSLQRVRQKLEKEKSELRMEVDDL 1280


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 36.6 bits (83), Expect = 0.050
 Identities = 48/238 (20%), Positives = 109/238 (45%), Gaps = 23/238 (9%)

Query: 174 QADNVQIGSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSREL 233
           Q + +Q     + + Q   Q  + + S++  E ++    ++LK +LQL  Q+     ++L
Sbjct: 105 QHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQ-----QQL 159

Query: 234 QLSMLEIVHPGQVEKHYREMEEKSALIIQ--KHWRGYRERKNFHQ--QRQSLIEYKAAVT 289
           Q        P QV++  R  +++  L  Q  +  +  ++++   Q  Q Q L++ +    
Sbjct: 160 Q--------PQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQL 211

Query: 290 LQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSREL 349
            Q+  L+   + ++++     ++  QE    ++  L  +    +++ L       + ++L
Sbjct: 212 QQQQLLQQQEQLQQQQ-----FQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQL 266

Query: 350 HAQAQERLQHYFMGRALEERAQQHREALIAQISTNV-EQLMKAPSLKEAEGKEPELFL 406
             Q Q +LQ   + +  E+  QQ ++ L+ Q    + +Q ++ P L+  E +E EL L
Sbjct: 267 LEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELEL 324



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 55/258 (21%), Positives = 114/258 (44%), Gaps = 40/258 (15%)

Query: 161 QNVLQSDHFLH-------LLQADNVQIGSAVMMMLQNILQINRSKRSKMLLEINRQKEEE 213
           Q VLQ    L        LLQ    Q+    ++  Q  LQ  + ++ +  L+  +Q++  
Sbjct: 185 QQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQ--QQQQLL 242

Query: 214 DLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKN 273
            L+ Q QLQ+Q   +   +LQ  +L        E+   +++++  L  Q+  +  ++++ 
Sbjct: 243 LLQQQGQLQQQLLQQQQAQLQQQLL--------EQQQAQLQQQLLLQQQEQLQQQQQQQL 294

Query: 274 FHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYV 333
             QQ++ L + +    LQ   L+   +   + +L     G ++  + +R EL+++ +   
Sbjct: 295 LQQQQEQLQQQQ----LQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELER 350

Query: 334 RRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPS 393
           ++           R+L  + QE LQ       LE++ +Q ++    Q+     QL   P 
Sbjct: 351 QQE---------QRQLQLKLQEELQQ------LEQQLEQQQQ----QLEQQEVQLELTPV 391

Query: 394 LKEAEGKEPELFLSRSRP 411
              A+ +E +L L+  +P
Sbjct: 392 ELGAQQQEVQLELTPVQP 409


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,326,475
Number of Sequences: 37866
Number of extensions: 693018
Number of successful extensions: 3369
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 173
Number of HSP's that attempted gapping in prelim test: 3016
Number of HSP's gapped (non-prelim): 464
length of query: 465
length of database: 18,247,518
effective HSP length: 106
effective length of query: 359
effective length of database: 14,233,722
effective search space: 5109906198
effective search space used: 5109906198
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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