BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|170014680 IQ motif containing B1 isoform c [Homo sapiens] (465 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|170014680 IQ motif containing B1 isoform c [Homo sapiens] 918 0.0 gi|170014684 IQ motif containing B1 isoform a [Homo sapiens] 533 e-151 gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 45 1e-04 gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 45 1e-04 gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 45 1e-04 gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 45 1e-04 gi|148746195 trichohyalin [Homo sapiens] 43 5e-04 gi|45439327 periplakin [Homo sapiens] 43 5e-04 gi|156119615 myosin IXA [Homo sapiens] 42 0.001 gi|21450705 leucine rich repeat containing 45 [Homo sapiens] 42 0.001 gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 42 0.001 gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 41 0.002 gi|32484977 angiomotin like 2 [Homo sapiens] 41 0.003 gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 40 0.006 gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 40 0.006 gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 40 0.006 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 40 0.006 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 40 0.006 gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 39 0.008 gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 39 0.008 gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 39 0.008 gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 39 0.010 gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 39 0.010 gi|70980531 GGA binding partner [Homo sapiens] 39 0.010 gi|28372509 Ymer protein short isoform [Homo sapiens] 38 0.022 gi|126116596 asp (abnormal spindle)-like, microcephaly associate... 37 0.029 gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 37 0.029 gi|17017963 forkhead box P2 isoform I [Homo sapiens] 37 0.038 gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 37 0.038 gi|221139761 zinc finger protein 853 [Homo sapiens] 37 0.050 >gi|170014680 IQ motif containing B1 isoform c [Homo sapiens] Length = 465 Score = 918 bits (2372), Expect = 0.0 Identities = 465/465 (100%), Positives = 465/465 (100%) Query: 1 MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ 60 MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ Sbjct: 1 MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ 60 Query: 61 YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR 120 YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR Sbjct: 61 YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR 120 Query: 121 QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI 180 QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI Sbjct: 121 QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI 180 Query: 181 GSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEI 240 GSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEI Sbjct: 181 GSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEI 240 Query: 241 VHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAK 300 VHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAK Sbjct: 241 VHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAK 300 Query: 301 CRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHY 360 CRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHY Sbjct: 301 CRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHY 360 Query: 361 FMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAH 420 FMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAH Sbjct: 361 FMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAH 420 Query: 421 LTTLKHIQAPWWKKLGEESGDEIDVPKDELSIELENLFIGGTKPP 465 LTTLKHIQAPWWKKLGEESGDEIDVPKDELSIELENLFIGGTKPP Sbjct: 421 LTTLKHIQAPWWKKLGEESGDEIDVPKDELSIELENLFIGGTKPP 465 >gi|170014684 IQ motif containing B1 isoform a [Homo sapiens] Length = 598 Score = 533 bits (1373), Expect = e-151 Identities = 270/270 (100%), Positives = 270/270 (100%) Query: 196 RSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEE 255 RSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEE Sbjct: 329 RSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEE 388 Query: 256 KSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQ 315 KSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQ Sbjct: 389 KSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQ 448 Query: 316 ELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHRE 375 ELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHRE Sbjct: 449 ELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHRE 508 Query: 376 ALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKL 435 ALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKL Sbjct: 509 ALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKL 568 Query: 436 GEESGDEIDVPKDELSIELENLFIGGTKPP 465 GEESGDEIDVPKDELSIELENLFIGGTKPP Sbjct: 569 GEESGDEIDVPKDELSIELENLFIGGTKPP 598 Score = 401 bits (1030), Expect = e-112 Identities = 235/427 (55%), Positives = 285/427 (66%), Gaps = 61/427 (14%) Query: 1 MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ 60 MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ Sbjct: 1 MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQ 60 Query: 61 YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR 120 YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR Sbjct: 61 YCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGR 120 Query: 121 QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI 180 QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI Sbjct: 121 QLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQI 180 Query: 181 GSAVMMMLQNILQIN-------------------------------RSKRSKMLLEINRQ 209 GSAVMMMLQNILQIN RS +K+LL + Sbjct: 181 GSAVMMMLQNILQINSGDLLRIGRKALYSILDEVIFKLFSTPSPVIRSTATKLLLLMAES 240 Query: 210 KEEEDLKL----------QLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSAL 259 +E + L +L +++ S+EL+ ++ ++ P ++ + ++A Sbjct: 241 HQEILILLRQSTCYKGLRRLLSKQETGTEFSQELR-QLVGLLSPMVYQEVEEQKLHQAAC 299 Query: 260 IIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTD 319 +IQ +W+G++ RK + A + LQR+ + ++ K L R +E Sbjct: 300 LIQAYWKGFQTRKRLKKLP------SAVIALQRS-----FRSKRSKMLLEINRQKEEEDL 348 Query: 320 ARRVELKKRVDDYVRRHLGSPMSDVVS--------RELHAQAQERLQHYFMGRALEERAQ 371 +++L+++ + R L M ++V RE+ ++ +Q ++ G + Sbjct: 349 KLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFH 408 Query: 372 QHREALI 378 Q R++LI Sbjct: 409 QQRQSLI 415 >gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens] Length = 1293 Score = 45.4 bits (106), Expect = 1e-04 Identities = 51/206 (24%), Positives = 91/206 (44%), Gaps = 19/206 (9%) Query: 188 LQNILQINRSKRSKML-----LEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSML---- 238 L+ + Q+ ++K +K+ E+ ++EEE+ K Q +L+RQ+ L R+ + Sbjct: 717 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 776 Query: 239 -EIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKF 297 E+ Q E R+ E++ AL R RE + QQ ++L + + K Sbjct: 777 EELARRKQEEALRRQREQEIAL------RRQREEEERQQQEEALRRLEERRREEEERRKQ 830 Query: 298 LAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERL 357 RK+++ A W +E R E + R+++ R L + +EL Q Q+ L Sbjct: 831 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR-LRHEEEERKRKELEVQRQKEL 889 Query: 358 --QHYFMGRALEERAQQHREALIAQI 381 Q AL QQ ++ +AQ+ Sbjct: 890 MRQRQQQQEALRRLQQQQQQQQLAQM 915 >gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens] Length = 1320 Score = 45.4 bits (106), Expect = 1e-04 Identities = 51/206 (24%), Positives = 91/206 (44%), Gaps = 19/206 (9%) Query: 188 LQNILQINRSKRSKML-----LEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSML---- 238 L+ + Q+ ++K +K+ E+ ++EEE+ K Q +L+RQ+ L R+ + Sbjct: 744 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 803 Query: 239 -EIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKF 297 E+ Q E R+ E++ AL R RE + QQ ++L + + K Sbjct: 804 EELARRKQEEALRRQREQEIAL------RRQREEEERQQQEEALRRLEERRREEEERRKQ 857 Query: 298 LAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERL 357 RK+++ A W +E R E + R+++ R L + +EL Q Q+ L Sbjct: 858 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR-LRHEEEERKRKELEVQRQKEL 916 Query: 358 --QHYFMGRALEERAQQHREALIAQI 381 Q AL QQ ++ +AQ+ Sbjct: 917 MRQRQQQQEALRRLQQQQQQQQLAQM 942 >gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 45.4 bits (106), Expect = 1e-04 Identities = 51/206 (24%), Positives = 91/206 (44%), Gaps = 19/206 (9%) Query: 188 LQNILQINRSKRSKML-----LEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSML---- 238 L+ + Q+ ++K +K+ E+ ++EEE+ K Q +L+RQ+ L R+ + Sbjct: 723 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 782 Query: 239 -EIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKF 297 E+ Q E R+ E++ AL R RE + QQ ++L + + K Sbjct: 783 EELARRKQEEALRRQREQEIAL------RRQREEEERQQQEEALRRLEERRREEEERRKQ 836 Query: 298 LAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERL 357 RK+++ A W +E R E + R+++ R L + +EL Q Q+ L Sbjct: 837 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR-LRHEEEERKRKELEVQRQKEL 895 Query: 358 --QHYFMGRALEERAQQHREALIAQI 381 Q AL QQ ++ +AQ+ Sbjct: 896 MRQRQQQQEALRRLQQQQQQQQLAQM 921 >gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 45.4 bits (106), Expect = 1e-04 Identities = 51/206 (24%), Positives = 91/206 (44%), Gaps = 19/206 (9%) Query: 188 LQNILQINRSKRSKML-----LEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSML---- 238 L+ + Q+ ++K +K+ E+ ++EEE+ K Q +L+RQ+ L R+ + Sbjct: 723 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 782 Query: 239 -EIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKF 297 E+ Q E R+ E++ AL R RE + QQ ++L + + K Sbjct: 783 EELARRKQEEALRRQREQEIAL------RRQREEEERQQQEEALRRLEERRREEEERRKQ 836 Query: 298 LAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERL 357 RK+++ A W +E R E + R+++ R L + +EL Q Q+ L Sbjct: 837 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR-LRHEEEERKRKELEVQRQKEL 895 Query: 358 --QHYFMGRALEERAQQHREALIAQI 381 Q AL QQ ++ +AQ+ Sbjct: 896 MRQRQQQQEALRRLQQQQQQQQLAQM 921 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 43.1 bits (100), Expect = 5e-04 Identities = 50/252 (19%), Positives = 103/252 (40%), Gaps = 22/252 (8%) Query: 189 QNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEK 248 Q + + + +R + L + + E+ L+ + QL+R++ +R ++L+ E H + E+ Sbjct: 381 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440 Query: 249 HYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAA--LKFLAKCRKKKK 306 RE K ++ W E H+Q + + K +R LK + R++++ Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ 500 Query: 307 LFAPWRGLQELTDARRVELKK-----------RVDDYVRRHLGSPMSDVVSRELHAQAQE 355 + +E + R LK+ R + +RR ++ RE + ++ Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ 560 Query: 356 RLQHYFMGRALEERAQQ--------HREALIAQISTNVEQLMKAPSLKEAEGKE-PELFL 406 + + R EER Q ++ L + +EQ +K ++ E +E E L Sbjct: 561 ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620 Query: 407 SRSRPVAAKAKQ 418 R P + +Q Sbjct: 621 KREEPEEERRQQ 632 Score = 36.6 bits (83), Expect = 0.050 Identities = 49/229 (21%), Positives = 97/229 (42%), Gaps = 12/229 (5%) Query: 196 RSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEE 255 +S++ + L + +RQ+ +E+L Q Q ++R R + E QL + + E+ E + Sbjct: 154 QSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCK---GHETEEFPDEEQL 210 Query: 256 KSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAP--WRG 313 + +++ +G E++ ++RQ + + R L K +K + P R Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270 Query: 314 LQE----LTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEER 369 LQE L R EL++ + ++ + R+ Q +ER + R +ER Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK---QEEERREQQEERREQQER 327 Query: 370 AQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQ 418 +Q E Q+ E+ + +E E + E L R + + +Q Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQ 376 Score = 34.3 bits (77), Expect = 0.25 Identities = 52/217 (23%), Positives = 91/217 (41%), Gaps = 39/217 (17%) Query: 209 QKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGY 268 Q+EEE+L+ + +R++ R +E Q E + Q E+ EE+ Q+ R Y Sbjct: 907 QEEEEELQRE---EREKRRRQEQERQYREEEQL---QQEEEQLLREEREKRRRQERERQY 960 Query: 269 RERKNFHQQRQSLI--------------EYKAAVTLQRAALKFLAKCRKKKKLFAPWRGL 314 R+ K Q+ + L+ +Y+ LQ+ + L + R+K++ R Sbjct: 961 RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR-----RQE 1015 Query: 315 QELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHR 374 E ++ EL++ + +R RE + QER + Y R EE Q+ Sbjct: 1016 WERQYRKKDELQQEEEQLLRE----------ERE-KRRLQERERQY---REEEELQQEEE 1061 Query: 375 EALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRP 411 + L + T Q ++ KE E ++ E L R P Sbjct: 1062 QLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098 Score = 33.1 bits (74), Expect = 0.55 Identities = 52/249 (20%), Positives = 104/249 (41%), Gaps = 36/249 (14%) Query: 168 HFLHLLQADNVQIGSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQ----- 222 H L+ A Q+ ++ + ++ R +R K RQ++E + + QLQ Sbjct: 887 HTLYAKPALQEQLRKEQQLLQEEEEELQREEREKR----RRQEQERQYREEEQLQQEEEQ 942 Query: 223 -------------RQRAMRLSRELQLSMLEIV-------HPGQVEKHYREMEEKSALIIQ 262 R+R R ++LQ +++ + EK YRE EE + Q Sbjct: 943 LLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEE----LQQ 998 Query: 263 KHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARR 322 + + RE + ++++ +Y+ LQ+ + L + R+K++L R +E + ++ Sbjct: 999 EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQ 1058 Query: 323 VELKKRVDD-YVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQI 381 E + ++ RR EL + ++ L+ R +ER +Q RE ++ Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREE--EEL 1116 Query: 382 STNVEQLMK 390 EQL++ Sbjct: 1117 QQEEEQLLR 1125 Score = 30.8 bits (68), Expect = 2.7 Identities = 50/225 (22%), Positives = 91/225 (40%), Gaps = 41/225 (18%) Query: 189 QNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEK 248 + +L+ R KR + E RQ ++D Q + Q R R R LQ + E+ Sbjct: 1001 EQLLREEREKRRRQ--EWERQYRKKDELQQEEEQLLREEREKRRLQ----------ERER 1048 Query: 249 HYRE-----MEEKSALIIQKHW-------RGYRERKNFHQQRQSLIEYKAAVTLQRAALK 296 YRE EE+ L ++ R YR+ + Q+ + L+ + +R + Sbjct: 1049 QYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPE---KRRRQE 1105 Query: 297 FLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQER 356 +CR++++L QE R E +KR + R E+ + ++ Sbjct: 1106 RERQCREEEEL------QQEEEQLLREEREKRRRQELERQYRE------EEEVQQEEEQL 1153 Query: 357 LQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKE 401 L+ R +E +Q+RE ++ EQL++ K + +E Sbjct: 1154 LREEPEKRRRQELERQYREE--EELQQEEEQLLREEQEKRRQERE 1196 Score = 30.0 bits (66), Expect = 4.7 Identities = 23/87 (26%), Positives = 40/87 (45%), Gaps = 17/87 (19%) Query: 193 QINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYRE 252 Q+ R +R + +LE + + E + + QL+RQ R RE E+ R+ Sbjct: 1739 QLRRQERYRKILEEEQLRPERE---EQQLRRQERDRKFRE--------------EEQLRQ 1781 Query: 253 MEEKSALIIQKHWRGYRERKNFHQQRQ 279 E+ L Q+ R +RE + Q+R+ Sbjct: 1782 EREEQQLRSQESDRKFREEEQLRQERE 1808 Score = 29.6 bits (65), Expect = 6.1 Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 17/100 (17%) Query: 193 QINRSKRSKMLLE---INRQKEEEDLKLQ---LQLQRQRAMRLSRELQLSMLEIVHPGQV 246 Q+ R +R + E + +++EE+ L+ Q + + + +R RE Q + P Q Sbjct: 1763 QLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQ-----LRPQQR 1817 Query: 247 EKHYR------EMEEKSALIIQKHWRGYRERKNFHQQRQS 280 + YR ++EE+ + Q+ R YR + F Q +S Sbjct: 1818 DGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKS 1857 >gi|45439327 periplakin [Homo sapiens] Length = 1756 Score = 43.1 bits (100), Expect = 5e-04 Identities = 75/295 (25%), Positives = 118/295 (40%), Gaps = 50/295 (16%) Query: 187 MLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQV 246 ++Q ILQ ++K + R K E+ K Q+ L+R+RA S+E Q++ E Sbjct: 1291 VVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERA---SQEEQIARKE------- 1340 Query: 247 EKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQ----RAALKFLAKCR 302 E+ ++Q+ Y E + + E Q RA L+ L + R Sbjct: 1341 ----EELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRR 1396 Query: 303 KKKKLFAPWRGLQELTDAR--RVELKKRVDDYVRRHLGSPMSDVVSRE---------LHA 351 + + R L+EL R R E ++ V +R + +RE L Sbjct: 1397 TELE-----RQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQ 1451 Query: 352 QAQERLQHYFMGRALEERAQQHREALIAQISTNVEQL-MKAPSLKEAEGKEPELFLSRSR 410 Q+ +H + LEE +QHR L + +E L K +L++AE KE ++ LS S Sbjct: 1452 DPQQAREHALLRLQLEE--EQHRRQL---LEGELETLRRKLAALEKAEVKE-KVVLSESV 1505 Query: 411 PVAAKAKQAHLTTLKHIQAPWWKKLGEESGD--EIDVPKDELSIELENLFIGGTK 463 V + + LK L EES E+DV L L L +K Sbjct: 1506 QVEKGDTEQEIQRLK-------SSLEEESRSKRELDVEVSRLEARLSELEFHNSK 1553 >gi|156119615 myosin IXA [Homo sapiens] Length = 2548 Score = 42.4 bits (98), Expect = 0.001 Identities = 41/167 (24%), Positives = 70/167 (41%), Gaps = 15/167 (8%) Query: 163 VLQSDHFLHLLQADNVQIGSAVMMMLQNILQINRSKRSKMLLEINRQKEE---EDLKLQL 219 +L HFLHL QA + + +N L K + + QK+ L Sbjct: 1033 LLCRQHFLHLRQASVI-----IQRFWRNYLN------QKQVRDAAVQKDAFVMASAAALL 1081 Query: 220 QLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQ 279 Q + + R L+L IV + +YR +A+ IQ W+ YRE K + +QR+ Sbjct: 1082 QASWRAHLERQRYLELRAAAIVIQQKWRDYYRR-RHMAAICIQARWKAYRESKRYQEQRK 1140 Query: 280 SLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELK 326 +I ++ RA +F A ++ + P GL + +E++ Sbjct: 1141 KIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLEIQ 1187 >gi|21450705 leucine rich repeat containing 45 [Homo sapiens] Length = 670 Score = 42.4 bits (98), Expect = 0.001 Identities = 54/214 (25%), Positives = 98/214 (45%), Gaps = 11/214 (5%) Query: 192 LQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLE---IVHPGQVEK 248 L+ + S R K + + R EE + +Q ++QR A RLS E +LS ++ + GQ E+ Sbjct: 426 LEDSESLRIKEVEHMTRHLEESEKAMQERVQRLEAARLSLEEELSRVKAAALSERGQAEE 485 Query: 249 HYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKK--- 305 + + ++ L Q+ ++ Q + + LQ+ + A+ R + Sbjct: 486 ELIKAKSQARLEEQQRLAHLEDKLRLLAQAR---DEAQGACLQQKQVVAEAQTRVSQLGL 542 Query: 306 KLFAPWRGLQELTDARRVELKKRVDDYVRRHLG-SPMSDVVSRELHAQAQERLQHYFMGR 364 ++ R L+EL ++ ++RV + R + + + EL AQ R + + R Sbjct: 543 QVEGLRRRLEELQQELSLKDQERVAEVSRVRVELQEQNGRLQAELAAQEALREKAAALER 602 Query: 365 ALEERAQQHREALIAQISTNVEQLMKAPSLKEAE 398 L+ A HREAL+ + S N L + L+EAE Sbjct: 603 QLKVMASDHREALLDRESENA-SLREKLRLREAE 635 Score = 39.3 bits (90), Expect = 0.008 Identities = 50/210 (23%), Positives = 92/210 (43%), Gaps = 32/210 (15%) Query: 209 QKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGY 268 Q++ ++LKL+ Q +R +L R+L + EK+ L+ ++ Sbjct: 338 QRQAKELKLEQQEAAERESKLLRDLSAA-----------------NEKNLLL--QNQVDE 378 Query: 269 RERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKR 328 ERK F Q++ L + + +T A LK A +++ R Q L D+ + +K+ Sbjct: 379 LERK-FRCQQEQLFQTRQEMTSMSAELKMRAIQAEERLDMEKRRCRQSLEDSESLRIKE- 436 Query: 329 VDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGR-ALEERAQQHREALIAQISTNVEQ 387 +++ RHL E QER+Q R +LEE + + A +++ E+ Sbjct: 437 -VEHMTRHL---------EESEKAMQERVQRLEAARLSLEEELSRVKAAALSERGQAEEE 486 Query: 388 LMKAPSLKEAEGKEPELFLSRSRPVAAKAK 417 L+KA S E ++ L + A+A+ Sbjct: 487 LIKAKSQARLEEQQRLAHLEDKLRLLAQAR 516 >gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo sapiens] Length = 551 Score = 42.0 bits (97), Expect = 0.001 Identities = 63/274 (22%), Positives = 121/274 (44%), Gaps = 29/274 (10%) Query: 158 ELIQNVLQSDHFLHLLQADNVQIGSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKL 217 E QN+LQ + L + Q + ++ S +++ + + K ++ EE+ L Sbjct: 171 ERAQNLLQRANKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQ 230 Query: 218 QLQLQRQRAMRLSRELQLSMLEIVHPGQ---VEKHYREMEEKSALIIQKHWRGYRERKNF 274 ++++RQ++++ EL+ E G+ VE+ + EE+S L Q+ Sbjct: 231 MMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQR----------- 279 Query: 275 HQQRQSLIEYKAAVTLQRAALKFLAKCRKKK-KLFAPWRGLQELTDARRVEL---KKRVD 330 Q+++ ++EY LQ LK + + +++K K+ A + + + ++ EL +K D Sbjct: 280 EQEKEQMLEYME--QLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLAD 337 Query: 331 DYVRRHLGSPMSDVVSRELHAQ--AQERLQHYFMGRALEERAQQH---REALIAQISTNV 385 V M+ E + +E+ + RA++E+AQ + ++AL A+ + V Sbjct: 338 QMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEV 397 Query: 386 EQLMKAPSLKEAEGK----EPELFLSRSRPVAAK 415 KE K E EL SR VA K Sbjct: 398 ADREWRRKEKENARKKMETEAELRKSRLEQVAFK 431 >gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo sapiens] Length = 2168 Score = 41.2 bits (95), Expect = 0.002 Identities = 35/186 (18%), Positives = 84/186 (45%), Gaps = 16/186 (8%) Query: 211 EEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRE 270 + D KL +LQ Q R + Q+ +L + + + +E +++ A++ + R +E Sbjct: 879 DNADAKLLRKLQAQEIAR--QAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKE 936 Query: 271 RKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVD 330 + +Q++ + + + + + + +KKKK +E +A+ +E +KR+ Sbjct: 937 QIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKK--------EEAANAKLLEAEKRIK 988 Query: 331 DYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMK 390 + R + + H + + R QH + +A+E R + + + Q + ++L K Sbjct: 989 EKEMRRQQAVLLK------HQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNK 1042 Query: 391 APSLKE 396 L++ Sbjct: 1043 ERKLEQ 1048 >gi|32484977 angiomotin like 2 [Homo sapiens] Length = 780 Score = 40.8 bits (94), Expect = 0.003 Identities = 65/292 (22%), Positives = 113/292 (38%), Gaps = 42/292 (14%) Query: 174 QADNVQIGSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSR-E 232 QA + GSA + ++ +L+ N Q++ E L+ +L+ ++A R+ + E Sbjct: 300 QASSATSGSAHLAQMEAVLRENA----------RLQRDNERLQRELESSAEKAGRIEKLE 349 Query: 233 LQLSMLEIVHPG---------QVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIE 283 ++ L H +EK R + +Q R RER +R + Sbjct: 350 SEIQRLSEAHESLTRASSKREALEKTMRNKMDSEMRRLQDFNRDLRERLESANRRLASKT 409 Query: 284 YKAAVTLQRAALKFLAKC-------RKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRH 336 +A Q K LA+ K ++ A RG E RR EL ++ + Sbjct: 410 QEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIE-DQRRRAELLEQALGNAQGR 468 Query: 337 LGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMK------ 390 ++ ++ + + ERLQ +G+ + A + RE L ++ T +EQ +K Sbjct: 469 AARAEEELRKKQAYVEKVERLQQA-LGQL--QAACEKREQLELRLRTRLEQELKALRAQQ 525 Query: 391 ----APSLKEAEGKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEE 438 AP G PEL R + K+ + L+ W +K EE Sbjct: 526 RQAGAPGGSSGSGGSPELSALRLSE-QLREKEEQILALEADMTKWEQKYLEE 576 >gi|189083802 myosin VIIA isoform 2 [Homo sapiens] Length = 2175 Score = 39.7 bits (91), Expect = 0.006 Identities = 50/226 (22%), Positives = 94/226 (41%), Gaps = 45/226 (19%) Query: 202 MLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALII 261 MLLE+ R K D + LQ + S L+L + +A +I Sbjct: 734 MLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL-------------------KNAATLI 774 Query: 262 QKHWRGYRERKNF-------------HQQRQSLIEYKAAVTLQRAALKFLAKCR----KK 304 Q+HWRG+ RKN+ H+ R+ +Y+ A ++ ++F A+CR +K Sbjct: 775 QRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLA---RQRIIQFQARCRAYLVRK 831 Query: 305 KKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGR 364 W L AR + + +R+ +R + + + ++ +E+L+ + Sbjct: 832 AFRHRLWAVLTVQAYARGM-IARRLHQRLRAEY---LWRLEAEKMRLAEEEKLRKEMSAK 887 Query: 365 ALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSR 410 +E A++ + +AQ++ E + KEA ++ EL R Sbjct: 888 KAKEEAERKHQERLAQLAR--EDAERELKEKEAARRKKELLEQMER 931 >gi|189083800 myosin VIIA isoform 3 [Homo sapiens] Length = 1204 Score = 39.7 bits (91), Expect = 0.006 Identities = 50/226 (22%), Positives = 94/226 (41%), Gaps = 45/226 (19%) Query: 202 MLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALII 261 MLLE+ R K D + LQ + S L+L + +A +I Sbjct: 734 MLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL-------------------KNAATLI 774 Query: 262 QKHWRGYRERKNF-------------HQQRQSLIEYKAAVTLQRAALKFLAKCR----KK 304 Q+HWRG+ RKN+ H+ R+ +Y+ A ++ ++F A+CR +K Sbjct: 775 QRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLA---RQRIIQFQARCRAYLVRK 831 Query: 305 KKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGR 364 W L AR + + +R+ +R + + + ++ +E+L+ + Sbjct: 832 AFRHRLWAVLTVQAYARGM-IARRLHQRLRAEY---LWRLEAEKMRLAEEEKLRKEMSAK 887 Query: 365 ALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSR 410 +E A++ + +AQ++ E + KEA ++ EL R Sbjct: 888 KAKEEAERKHQERLAQLAR--EDAERELKEKEAARRKKELLEQMER 931 >gi|189083798 myosin VIIA isoform 1 [Homo sapiens] Length = 2215 Score = 39.7 bits (91), Expect = 0.006 Identities = 50/226 (22%), Positives = 94/226 (41%), Gaps = 45/226 (19%) Query: 202 MLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALII 261 MLLE+ R K D + LQ + S L+L + +A +I Sbjct: 734 MLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL-------------------KNAATLI 774 Query: 262 QKHWRGYRERKNF-------------HQQRQSLIEYKAAVTLQRAALKFLAKCR----KK 304 Q+HWRG+ RKN+ H+ R+ +Y+ A ++ ++F A+CR +K Sbjct: 775 QRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLA---RQRIIQFQARCRAYLVRK 831 Query: 305 KKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGR 364 W L AR + + +R+ +R + + + ++ +E+L+ + Sbjct: 832 AFRHRLWAVLTVQAYARGM-IARRLHQRLRAEY---LWRLEAEKMRLAEEEKLRKEMSAK 887 Query: 365 ALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSR 410 +E A++ + +AQ++ E + KEA ++ EL R Sbjct: 888 KAKEEAERKHQERLAQLAR--EDAERELKEKEAARRKKELLEQMER 931 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 39.7 bits (91), Expect = 0.006 Identities = 50/221 (22%), Positives = 94/221 (42%), Gaps = 12/221 (5%) Query: 188 LQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVE 247 L+ +LQ R + +M E +Q E++ ++ + ++ + RL+ E +VE Sbjct: 578 LRKVLQA-RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 636 Query: 248 KHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAA-LKFLAKCRKKKK 306 ++ EE L W E + HQ+ + + L++AA K LA+ R++++ Sbjct: 637 ARRKQEEEARRL----RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER 692 Query: 307 LFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQE---RLQHYFMG 363 R + RR + ++ + + + + E Q +E RLQ + Sbjct: 693 REQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ 752 Query: 364 RALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPEL 404 R LEE+ ++ + +A+ EQ KA KEA G L Sbjct: 753 RELEEKKKKEEQQRLAERQLQEEQEKKA---KEAAGASKAL 790 Score = 37.7 bits (86), Expect = 0.022 Identities = 44/240 (18%), Positives = 105/240 (43%), Gaps = 13/240 (5%) Query: 193 QINRSKRSKMLLEINRQKEEEDLKLQLQ-LQRQRAMRLSRELQ----LSMLEIVHPGQVE 247 ++ +R + ++ RQK EED + +L+ ++ +R RL + LQ + ++ Q+E Sbjct: 541 RLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIE 600 Query: 248 KHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKK--- 304 + + +++EK+ ++ + +K ++ +E + + L++L + ++ Sbjct: 601 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 660 Query: 305 -----KKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQH 359 KK L++ +A+R+ ++ + + + RE + QER Sbjct: 661 QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLA 720 Query: 360 YFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQA 419 R +ER Q RE + + +++ L+E + KE + L+ + + K+A Sbjct: 721 EQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 780 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 39.7 bits (91), Expect = 0.006 Identities = 50/221 (22%), Positives = 94/221 (42%), Gaps = 12/221 (5%) Query: 188 LQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVE 247 L+ +LQ R + +M E +Q E++ ++ + ++ + RL+ E +VE Sbjct: 574 LRKVLQA-RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 632 Query: 248 KHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAA-LKFLAKCRKKKK 306 ++ EE L W E + HQ+ + + L++AA K LA+ R++++ Sbjct: 633 ARRKQEEEARRL----RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER 688 Query: 307 LFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQE---RLQHYFMG 363 R + RR + ++ + + + + E Q +E RLQ + Sbjct: 689 REQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ 748 Query: 364 RALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPEL 404 R LEE+ ++ + +A+ EQ KA KEA G L Sbjct: 749 RELEEKKKKEEQQRLAERQLQEEQEKKA---KEAAGASKAL 786 Score = 37.7 bits (86), Expect = 0.022 Identities = 44/240 (18%), Positives = 105/240 (43%), Gaps = 13/240 (5%) Query: 193 QINRSKRSKMLLEINRQKEEEDLKLQLQ-LQRQRAMRLSRELQ----LSMLEIVHPGQVE 247 ++ +R + ++ RQK EED + +L+ ++ +R RL + LQ + ++ Q+E Sbjct: 537 RLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIE 596 Query: 248 KHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKK--- 304 + + +++EK+ ++ + +K ++ +E + + L++L + ++ Sbjct: 597 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 656 Query: 305 -----KKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQH 359 KK L++ +A+R+ ++ + + + RE + QER Sbjct: 657 QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLA 716 Query: 360 YFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQA 419 R +ER Q RE + + +++ L+E + KE + L+ + + K+A Sbjct: 717 EQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 776 >gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] Length = 2003 Score = 39.3 bits (90), Expect = 0.008 Identities = 60/254 (23%), Positives = 103/254 (40%), Gaps = 30/254 (11%) Query: 205 EINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKH 264 E +RQ + E +LQ +Q A + E L++ E ++ EE L+ ++ Sbjct: 961 ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQL-EKVTTEAKMKKFEEDLLLLEDQN 1019 Query: 265 WRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVE 324 + +ERK + L E+ + + +K L K R K + + ++ D R E Sbjct: 1020 SKLSKERKLLEDR---LAEFSSQAAEEEEKVKSLNKLRLKYEAT-----IADMEDRLRKE 1071 Query: 325 LKKRVD-DYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQIST 383 K R + + ++R L D S EL Q E+ QQ E L AQ+ Sbjct: 1072 EKGRQELEKLKRRL-----DGESSELQEQMVEQ--------------QQRAEELRAQLGR 1112 Query: 384 NVEQLMKAPSLKEAE-GKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESGDE 442 E+L A + E E G +L S AA A+ + + +K + G+E Sbjct: 1113 KEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE 1172 Query: 443 IDVPKDELSIELEN 456 ++ + EL L++ Sbjct: 1173 LEALRGELEDTLDS 1186 >gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] Length = 1995 Score = 39.3 bits (90), Expect = 0.008 Identities = 60/254 (23%), Positives = 103/254 (40%), Gaps = 30/254 (11%) Query: 205 EINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKH 264 E +RQ + E +LQ +Q A + E L++ E ++ EE L+ ++ Sbjct: 953 ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQL-EKVTTEAKMKKFEEDLLLLEDQN 1011 Query: 265 WRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVE 324 + +ERK + L E+ + + +K L K R K + + ++ D R E Sbjct: 1012 SKLSKERKLLEDR---LAEFSSQAAEEEEKVKSLNKLRLKYEAT-----IADMEDRLRKE 1063 Query: 325 LKKRVD-DYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQIST 383 K R + + ++R L D S EL Q E+ QQ E L AQ+ Sbjct: 1064 EKGRQELEKLKRRL-----DGESSELQEQMVEQ--------------QQRAEELRAQLGR 1104 Query: 384 NVEQLMKAPSLKEAE-GKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESGDE 442 E+L A + E E G +L S AA A+ + + +K + G+E Sbjct: 1105 KEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE 1164 Query: 443 IDVPKDELSIELEN 456 ++ + EL L++ Sbjct: 1165 LEALRGELEDTLDS 1178 >gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] Length = 2036 Score = 39.3 bits (90), Expect = 0.008 Identities = 60/254 (23%), Positives = 103/254 (40%), Gaps = 30/254 (11%) Query: 205 EINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKH 264 E +RQ + E +LQ +Q A + E L++ E ++ EE L+ ++ Sbjct: 994 ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQL-EKVTTEAKMKKFEEDLLLLEDQN 1052 Query: 265 WRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVE 324 + +ERK + L E+ + + +K L K R K + + ++ D R E Sbjct: 1053 SKLSKERKLLEDR---LAEFSSQAAEEEEKVKSLNKLRLKYEAT-----IADMEDRLRKE 1104 Query: 325 LKKRVD-DYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQIST 383 K R + + ++R L D S EL Q E+ QQ E L AQ+ Sbjct: 1105 EKGRQELEKLKRRL-----DGESSELQEQMVEQ--------------QQRAEELRAQLGR 1145 Query: 384 NVEQLMKAPSLKEAE-GKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESGDE 442 E+L A + E E G +L S AA A+ + + +K + G+E Sbjct: 1146 KEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE 1205 Query: 443 IDVPKDELSIELEN 456 ++ + EL L++ Sbjct: 1206 LEALRGELEDTLDS 1219 >gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo sapiens] Length = 1870 Score = 38.9 bits (89), Expect = 0.010 Identities = 50/230 (21%), Positives = 99/230 (43%), Gaps = 20/230 (8%) Query: 192 LQINRSKRSKMLLEINRQKEEEDLKLQ-LQLQRQRAMRLSRELQLSMLEIVHPGQVEKHY 250 L I + K L N++ ++ + +LQ L+++ Q + EL++S + Q+EK Sbjct: 761 LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE---QLEKEN 817 Query: 251 REMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAP 310 + +E++++ + + + +E K QQ + TL+ +K + K+ K + Sbjct: 818 KSLEQETSQLEKDKKQLEKENKRLRQQAEI-----KDTTLEENNVK-IGNLEKENKTLSK 871 Query: 311 WRGLQELTDARRVELKKRVDDYVRR------HLGSPMSDVVSRELHAQAQ----ERLQHY 360 G+ + + R EL+K + V+R L + D+VS +L Q E+L H Sbjct: 872 EIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHE 931 Query: 361 FMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSR 410 L + H E +E +++ K E KE ++ +R Sbjct: 932 LEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEAR 981 >gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] Length = 2230 Score = 38.9 bits (89), Expect = 0.010 Identities = 50/248 (20%), Positives = 114/248 (45%), Gaps = 40/248 (16%) Query: 209 QKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHY---REMEEKSALIIQKHW 265 +K+E +L+ +L+ Q R M L + +EI +V K+Y +++E K + +H+ Sbjct: 1510 EKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHF 1569 Query: 266 RGYRERKN--FHQQRQSLIEYKAAVTLQRAALKF---------LAKCRKKKKLFAPWRGL 314 + E K+ + + ++ + V +A L+ L+ K+++L A L Sbjct: 1570 QELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRL 1629 Query: 315 QELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHR 374 + + A+ ELK++ + + + ++L +Q +E+ EE+ ++ Sbjct: 1630 ESESAAKLAELKRKAEQKIA---------AIKKQLLSQMEEK----------EEQYKKGT 1670 Query: 375 EALIAQISTNVEQLMK-----APSLKEAEGKEPE-LFLSRS-RPVAAKAKQAHLTTLKHI 427 E+ +++++T +++ + LK E + E L + RS + VAA +Q + + Sbjct: 1671 ESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCV 1730 Query: 428 QAPWWKKL 435 Q + +K+ Sbjct: 1731 QKTYEEKI 1738 Score = 30.8 bits (68), Expect = 2.7 Identities = 57/272 (20%), Positives = 113/272 (41%), Gaps = 29/272 (10%) Query: 190 NILQINRSKRSKMLLEINRQKEE---EDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQV 246 ++LQ N +++ K+L + ++KEE +++ Q Q +R ++L + G + Sbjct: 1739 SVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQ-ERLIKLEHAEAKQHEDQSMIGHL 1797 Query: 247 EKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSL--IEYKAAVTLQRAALKFLAKCRKK 304 ++ E +K +LI+ +H + N Q +Q+L + TLQ L +K Sbjct: 1798 QEELEEKNKKYSLIVAQHVEKEGGKNNI-QAKQNLENVFDDVQKTLQEKELTCQILEQKI 1856 Query: 305 KKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMS--DVVSRELHAQAQERLQ-HYF 361 K+L + L + RVE+++ Y + M + + L +E+ + H Sbjct: 1857 KELDS---CLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLV 1913 Query: 362 MGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHL 421 + L QH + +L A K+ GKE + L + + K Q L Sbjct: 1914 QPKLLSNMEAQHNDLEF--------KLAGAEREKQKLGKE-IVRLQKDLRMLRKEHQQEL 1964 Query: 422 TTLKHIQAPWWKKLGEESGDEIDVPKDELSIE 453 LK K+ +E ++I +++L ++ Sbjct: 1965 EILK-------KEYDQEREEKIKQEQEDLELK 1989 >gi|70980531 GGA binding partner [Homo sapiens] Length = 441 Score = 38.9 bits (89), Expect = 0.010 Identities = 51/235 (21%), Positives = 111/235 (47%), Gaps = 35/235 (14%) Query: 206 INRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHW 265 I Q++ L+++L++ + R+ ++++ S++E +EK + + +E+ A+ Q + Sbjct: 132 IQLQQKISSLEIKLKVSEEEKQRIKQDVE-SLME--KHNVLEKGFLKEKEQEAISFQDRY 188 Query: 266 RGYRE---------RKNFHQQRQSLI-EYKAAVTLQRAALKFLAKCRKKKKLFAPWRGL- 314 + +E RK H+ ++ EYKA L ++++K + +K+ + A + Sbjct: 189 KELQEKHKQELEDMRKAGHEALSIIVDEYKA---LLQSSVKQQVEAIEKQYISAIEKQAH 245 Query: 315 --QELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQ 372 +EL +A+ L + +D + L + + + L Q+QE Q + + LEE Q+ Sbjct: 246 KCEELLNAQHQRLLEMLD--TEKEL---LKEKIKEALIQQSQE--QKEILEKCLEEERQR 298 Query: 373 HREALIAQISTNVEQLMKA---------PSLKEAEGKEPELFLSRSRPVAAKAKQ 418 ++EAL++ E + A +L++A +E EL+ + K Q Sbjct: 299 NKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQEKVSQ 353 >gi|28372509 Ymer protein short isoform [Homo sapiens] Length = 306 Score = 37.7 bits (86), Expect = 0.022 Identities = 64/292 (21%), Positives = 109/292 (37%), Gaps = 67/292 (22%) Query: 163 VLQSDHFLHLLQADNVQIGSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQ 222 VL+ H LQ ++ A + ++Q + L++ +Q +EEDLK Q QLQ Sbjct: 23 VLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHD--------LQVAKQLQEEDLKAQAQLQ 74 Query: 223 RQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLI 282 K Y+++E++ I Q+ +E+ +R+ + Sbjct: 75 -------------------------KRYKDLEQQDCEIAQE----IQEKLAIEAERRRIQ 105 Query: 283 EYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVE---LKKRVDDYVRRHLGS 339 E K + K L + +K+KK F + + D+ E +K RV Sbjct: 106 EKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRV---------- 155 Query: 340 PMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEG 399 M + VS ++ R Q ++ A R Q E L Q+ Q+ + + Sbjct: 156 -MKEAVSTP--SRMAHRDQEWY--DAEIARKLQEEELLATQVDMRAAQVAQDEEI----- 205 Query: 400 KEPELFLSRSRPVAAKAKQAHLTTL-KHIQAPWWK----KLGEESGDEIDVP 446 L ++ + KAK+ ++L K Q P WK K E D P Sbjct: 206 --ARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEP 255 >gi|126116596 asp (abnormal spindle)-like, microcephaly associated [Homo sapiens] Length = 3477 Score = 37.4 bits (85), Expect = 0.029 Identities = 38/155 (24%), Positives = 72/155 (46%), Gaps = 16/155 (10%) Query: 257 SALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQ---------RAALKFLAKCRKKKKL 307 S + IQ ++R Y +K F + + I+ ++ V ++ RAA F+ +C + KK+ Sbjct: 1658 SVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKI 1717 Query: 308 FAPWRGLQELTDARR--VELKKRVDDY-VRRHLGSPMSDVVSRELHAQAQERLQHYFMGR 364 A R +E R ++L+ V Y VR+ + V+S + + + ++ Q+Y Sbjct: 1718 AAQKR--EEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMY 1775 Query: 365 ALEERAQQHREALIAQIS--TNVEQLMKAPSLKEA 397 Q + A AQ++ N Q+ KA + +A Sbjct: 1776 KAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQA 1810 Score = 32.7 bits (73), Expect = 0.72 Identities = 29/136 (21%), Positives = 66/136 (48%), Gaps = 9/136 (6%) Query: 189 QNILQINRSKRSKMLLEINR----QKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPG 244 ++IL I + ++ + +I R QK ++LQ +R +A L R+++ + + + Sbjct: 1512 ESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWR 1571 Query: 245 QVEKHYREMEEKSALI-IQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRK 303 + R + K +I Q H R +++R+ + + +++ + + A+K LA +K Sbjct: 1572 MRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQK 1631 Query: 304 KKK----LFAPWRGLQ 315 + L + +RG+Q Sbjct: 1632 TRSAVIVLQSAYRGMQ 1647 Score = 32.0 bits (71), Expect = 1.2 Identities = 41/220 (18%), Positives = 93/220 (42%), Gaps = 37/220 (16%) Query: 191 ILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQ----- 245 +L + + R+ L++ +K + L+ +R++A R+ +QL+++ + + Sbjct: 1260 LLDLRKEIRAARLIQTTWRKYKLKTDLKRHQEREKAARI---IQLAVINFLAKQRLRKRV 1316 Query: 246 -----VEKHYR-----------------EMEEKSALIIQKHWRGYRERKNFHQQRQSLIE 283 ++K++R +++ K+A +IQ +WR Y R+ F + + I Sbjct: 1317 NAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSII 1376 Query: 284 YKAAVTLQRAALKFLAKCRKKKKLFAPWRG-LQELTDARRVELKKRVDDYVRRHLGSPMS 342 ++ + + A + + WR L+ D +R E+ K ++ S Sbjct: 1377 LQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQ----SMFR 1432 Query: 343 DVVSRELHAQAQER--LQHYFMGRALEERAQQHREALIAQ 380 R++ +Q + LQ F L ++A++ A+I Q Sbjct: 1433 KWKQRKMQSQVKATVILQRAFREWHLRKQAKEENSAIIIQ 1472 Score = 31.6 bits (70), Expect = 1.6 Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 4/103 (3%) Query: 224 QRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIE 283 QR L + + L+ + G + + + +AL IQ +RGY +R + QS+I+ Sbjct: 1794 QRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIK 1853 Query: 284 ----YKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARR 322 Y+A TL FL L + +RG + RR Sbjct: 1854 IQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRR 1896 Score = 30.8 bits (68), Expect = 2.7 Identities = 25/90 (27%), Positives = 49/90 (54%), Gaps = 11/90 (12%) Query: 217 LQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQ 276 L+ QLQRQ + +++ + V++ ++ +K+AL+IQK++R Y + + Sbjct: 1963 LRRQLQRQHKCAI-------IIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGR---E 2012 Query: 277 QRQSLIEYKAAVTLQRAALKFLAKCRKKKK 306 Q ++ KAAV ++A + + K RK+ K Sbjct: 2013 QNHLYLKTKAAVVTLQSAYRGM-KVRKRIK 2041 Score = 30.0 bits (66), Expect = 4.7 Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 6/95 (6%) Query: 218 QLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQ 277 Q L R+ A+ L + + L H QV R S +IIQ +G+ +++ F + Sbjct: 2878 QFLLYRKAAVVLQNHYR-AFLSAKHQRQVYLQIRS----SVIIIQARSKGFIQKRKFQEI 2932 Query: 278 RQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWR 312 + S I+ +A RA K+L K + K+ A +R Sbjct: 2933 KNSTIKIQAMWRRYRAK-KYLCKVKAACKIQAWYR 2966 Score = 29.3 bits (64), Expect = 7.9 Identities = 22/121 (18%), Positives = 56/121 (46%), Gaps = 12/121 (9%) Query: 189 QNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLE--IVHPG-- 244 Q + Q N K+ + ++ ++K Q+Q Q Q A+ + + + + +H Sbjct: 2594 QKVFQHNELKKETC---VQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRAT 2650 Query: 245 --QVEKHYREM---EEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLA 299 +++ YR++ ++ + IQ ++RG++ RK+ ++ ++ + RA + + Sbjct: 2651 VVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYET 2710 Query: 300 K 300 K Sbjct: 2711 K 2711 >gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sapiens] Length = 1843 Score = 37.4 bits (85), Expect = 0.029 Identities = 56/255 (21%), Positives = 109/255 (42%), Gaps = 26/255 (10%) Query: 192 LQINRSKRSKMLLEINRQKEEEDLKLQ-LQLQRQRAMRLSRELQLSMLEIVHPGQVEKHY 250 L I + K L N++ ++ + +LQ L+++ Q + EL++S + Q+EK Sbjct: 761 LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE---QLEKEN 817 Query: 251 REMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAP 310 + +E++++ + + + +E K QQ + TL+ +K + K+ K + Sbjct: 818 KSLEQETSQLEKDKKQLEKENKRLRQQAEI-----KDTTLEENNVK-IGNLEKENKTLSK 871 Query: 311 WRGLQELTDARRVELKKRVDDYVRR------HLGSPMSDVVSRELHAQAQ----ERLQHY 360 G+ + + R EL+K + V+R L + D+VS +L Q E+L H Sbjct: 872 EIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHE 931 Query: 361 FMGRALEERAQQHRE-----ALIAQISTNVEQ-LMKAPSLKEAEGKEPELFLSRSRPVAA 414 L + H E + + + +E L K+ +KE + E L S Sbjct: 932 LEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQ 991 Query: 415 KAKQAHLTTLKHIQA 429 + +Q T K+ +A Sbjct: 992 QLRQELKTVKKNYEA 1006 >gi|17017963 forkhead box P2 isoform I [Homo sapiens] Length = 715 Score = 37.0 bits (84), Expect = 0.038 Identities = 52/239 (21%), Positives = 102/239 (42%), Gaps = 31/239 (12%) Query: 74 QGGWTTISQLTQILSHCCVGLEPGEDAEEFYN-ELLPSAAENFLVLGRQL----QTCFIN 128 Q G +T+S +Q+ + G G+ + E ELL + L RQL QT + Sbjct: 17 QNGMSTLS--SQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLK 74 Query: 129 AAKAEEKDELLHF---FQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQIGSAVM 185 + K+ +K L ++T + L Q VL LLQ AVM Sbjct: 75 SPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQ-----AVM 129 Query: 186 MMLQNILQINRSKRSKMLLEI------NRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLE 239 + Q + + + ++ ++ L++ +Q++++ + Q Q Q+Q+ + ++ Q + Sbjct: 130 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 189 Query: 240 IVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQ---QRQSLIEYKAAVTLQRAAL 295 HPG+ K ++ +++ + ++ F Q Q Q L + + ++LQR L Sbjct: 190 QQHPGKQAKEQQQQQQQQQQLA-------AQQLVFQQQLLQMQQLQQQQHLLSLQRQGL 241 Score = 30.0 bits (66), Expect = 4.7 Identities = 34/208 (16%), Positives = 92/208 (44%), Gaps = 25/208 (12%) Query: 191 ILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHY 250 +L + + + + ++ Q++ LK +QR +++ + + +++ P Q+++ Sbjct: 49 LLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQ-- 106 Query: 251 REMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAP 310 I+Q+ QQ Q+L++ + AV LQ+ L+ K +++++L Sbjct: 107 ---------ILQQQVLS-------PQQLQALLQQQQAVMLQQQQLQEFYK-KQQEQLHL- 148 Query: 311 WRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERA 370 +L ++ + +++ ++ ++ Q Q++ QH +++ Sbjct: 149 -----QLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 203 Query: 371 QQHREALIAQISTNVEQLMKAPSLKEAE 398 QQ ++ L AQ +QL++ L++ + Sbjct: 204 QQQQQQLAAQQLVFQQQLLQMQQLQQQQ 231 >gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo sapiens] Length = 1983 Score = 37.0 bits (84), Expect = 0.038 Identities = 42/151 (27%), Positives = 72/151 (47%), Gaps = 15/151 (9%) Query: 319 DARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALI 378 D+ +L RV+D + LG+ M + +EL A+A+E + RA R ++ R Sbjct: 1133 DSELSQLSLRVED--EQLLGAQMQKKI-KELQARAEELEEELEAERAARARVEKQRAEAA 1189 Query: 379 AQISTNVEQLMKA--PSLKEAEG---KEPEL-FLSRSRPVAAKAKQAHLTTLKHIQAPWW 432 ++ E+L +A S + EG +E EL L R AA +A + L+ QA Sbjct: 1190 RELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGA 1249 Query: 433 KKLGEESG------DEIDVPKDELSIELENL 457 +LGE+ +++ K EL +E+++L Sbjct: 1250 AELGEQVDSLQRVRQKLEKEKSELRMEVDDL 1280 >gi|221139761 zinc finger protein 853 [Homo sapiens] Length = 659 Score = 36.6 bits (83), Expect = 0.050 Identities = 48/238 (20%), Positives = 109/238 (45%), Gaps = 23/238 (9%) Query: 174 QADNVQIGSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSREL 233 Q + +Q + + Q Q + + S++ E ++ ++LK +LQL Q+ ++L Sbjct: 105 QHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQ-----QQL 159 Query: 234 QLSMLEIVHPGQVEKHYREMEEKSALIIQ--KHWRGYRERKNFHQ--QRQSLIEYKAAVT 289 Q P QV++ R +++ L Q + + ++++ Q Q Q L++ + Sbjct: 160 Q--------PQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQL 211 Query: 290 LQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSREL 349 Q+ L+ + ++++ ++ QE ++ L + +++ L + ++L Sbjct: 212 QQQQLLQQQEQLQQQQ-----FQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQL 266 Query: 350 HAQAQERLQHYFMGRALEERAQQHREALIAQISTNV-EQLMKAPSLKEAEGKEPELFL 406 Q Q +LQ + + E+ QQ ++ L+ Q + +Q ++ P L+ E +E EL L Sbjct: 267 LEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELEL 324 Score = 32.0 bits (71), Expect = 1.2 Identities = 55/258 (21%), Positives = 114/258 (44%), Gaps = 40/258 (15%) Query: 161 QNVLQSDHFLH-------LLQADNVQIGSAVMMMLQNILQINRSKRSKMLLEINRQKEEE 213 Q VLQ L LLQ Q+ ++ Q LQ + ++ + L+ +Q++ Sbjct: 185 QQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQ--QQQQLL 242 Query: 214 DLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKN 273 L+ Q QLQ+Q + +LQ +L E+ +++++ L Q+ + ++++ Sbjct: 243 LLQQQGQLQQQLLQQQQAQLQQQLL--------EQQQAQLQQQLLLQQQEQLQQQQQQQL 294 Query: 274 FHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYV 333 QQ++ L + + LQ L+ + + +L G ++ + +R EL+++ + Sbjct: 295 LQQQQEQLQQQQ----LQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELER 350 Query: 334 RRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPS 393 ++ R+L + QE LQ LE++ +Q ++ Q+ QL P Sbjct: 351 QQE---------QRQLQLKLQEELQQ------LEQQLEQQQQ----QLEQQEVQLELTPV 391 Query: 394 LKEAEGKEPELFLSRSRP 411 A+ +E +L L+ +P Sbjct: 392 ELGAQQQEVQLELTPVQP 409 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.134 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,326,475 Number of Sequences: 37866 Number of extensions: 693018 Number of successful extensions: 3369 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 22 Number of HSP's successfully gapped in prelim test: 173 Number of HSP's that attempted gapping in prelim test: 3016 Number of HSP's gapped (non-prelim): 464 length of query: 465 length of database: 18,247,518 effective HSP length: 106 effective length of query: 359 effective length of database: 14,233,722 effective search space: 5109906198 effective search space used: 5109906198 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.