Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 169790958
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169790958 methionine synthase reductase isoform 1 [Homo
sapiens]
(698 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169790958 methionine synthase reductase isoform 1 [Homo sapiens] 1400 0.0
gi|169790956 methionine synthase reductase isoform 2 [Homo sapiens] 1400 0.0
gi|40254422 nitric oxide synthase 3 isoform 1 [Homo sapiens] 219 7e-57
gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens] 218 1e-56
gi|127139033 cytochrome P450 reductase [Homo sapiens] 211 2e-54
gi|24041029 nitric oxide synthase 2A [Homo sapiens] 188 2e-47
gi|221316705 NADPH dependent diflavin oxidoreductase 1 isoform a... 181 3e-45
gi|7657393 NADPH dependent diflavin oxidoreductase 1 isoform b [... 180 5e-45
gi|221316709 NADPH dependent diflavin oxidoreductase 1 isoform c... 166 5e-41
gi|221316707 NADPH dependent diflavin oxidoreductase 1 isoform d... 145 1e-34
gi|50726981 radical S-adenosyl methionine and flavodoxin domains... 47 8e-05
gi|62241003 cardiomyopathy associated 5 [Homo sapiens] 39 0.012
gi|231571329 nitric oxide synthase 3 isoform 3 [Homo sapiens] 39 0.016
gi|231571356 nitric oxide synthase 3 isoform 4 [Homo sapiens] 38 0.036
gi|231571314 nitric oxide synthase 3 isoform 2 [Homo sapiens] 38 0.036
gi|55742678 glucocorticoid induced transcript 1 [Homo sapiens] 38 0.036
gi|113722133 senataxin [Homo sapiens] 34 0.40
gi|116805344 proline rich, lacrimal 1 [Homo sapiens] 32 2.0
gi|8923900 cytidine monophospho-N-acetylneuraminic acid syntheta... 32 2.6
gi|156416003 succinate dehydrogenase complex, subunit A, flavopr... 31 3.4
gi|153792230 hypothetical protein LOC57670 [Homo sapiens] 31 3.4
gi|153251766 hypothetical protein LOC56181 isoform a [Homo sapiens] 30 5.8
gi|153251748 hypothetical protein LOC56181 isoform a [Homo sapiens] 30 5.8
gi|153251745 hypothetical protein LOC56181 isoform a [Homo sapiens] 30 5.8
gi|19923907 oxidoreductase NAD-binding domain containing 1 [Homo... 30 5.8
gi|38569394 inhibitor of kappa light polypeptide gene enhancer i... 30 7.6
gi|110349721 titin isoform novex-3 [Homo sapiens] 30 9.9
gi|153791492 eukaryotic translation initiation factor 3, subunit... 30 9.9
gi|110349719 titin isoform N2-A [Homo sapiens] 30 9.9
gi|110349717 titin isoform novex-2 [Homo sapiens] 30 9.9
>gi|169790958 methionine synthase reductase isoform 1 [Homo sapiens]
Length = 698
Score = 1400 bits (3623), Expect = 0.0
Identities = 698/698 (100%), Positives = 698/698 (100%)
Query: 1 MRRFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTT 60
MRRFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTT
Sbjct: 1 MRRFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTT 60
Query: 61 GTGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGA 120
GTGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGA
Sbjct: 61 GTGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGA 120
Query: 121 RHFYDTGHADDCVGLELVVEPWIAGLWPALRKHFRSSRGQEEISGALPVASPASSRTDLV 180
RHFYDTGHADDCVGLELVVEPWIAGLWPALRKHFRSSRGQEEISGALPVASPASSRTDLV
Sbjct: 121 RHFYDTGHADDCVGLELVVEPWIAGLWPALRKHFRSSRGQEEISGALPVASPASSRTDLV 180
Query: 181 KSELLHIESQVELLRFDDSGRKDSEVLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASL 240
KSELLHIESQVELLRFDDSGRKDSEVLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASL
Sbjct: 181 KSELLHIESQVELLRFDDSGRKDSEVLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASL 240
Query: 241 NIPGLPPEYLQVHLQESLGQEESQVSVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDI 300
NIPGLPPEYLQVHLQESLGQEESQVSVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDI
Sbjct: 241 NIPGLPPEYLQVHLQESLGQEESQVSVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDI 300
Query: 301 SNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQHI 360
SNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQHI
Sbjct: 301 SNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQHI 360
Query: 361 PAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRDA 420
PAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRDA
Sbjct: 361 PAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRDA 420
Query: 421 CACLLDLLLAFPSCQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTAT 480
CACLLDLLLAFPSCQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTAT
Sbjct: 421 CACLLDLLLAFPSCQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTAT 480
Query: 481 TEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPDDPSIPI 540
TEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPDDPSIPI
Sbjct: 481 TEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPDDPSIPI 540
Query: 541 IMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKELRHFLKHG 600
IMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKELRHFLKHG
Sbjct: 541 IMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKELRHFLKHG 600
Query: 601 ILTHLKVSFSRDAPVGEEEAPAKYVQDNIQLHGQQVARILLQENGHIYVCGDAKNMAKDV 660
ILTHLKVSFSRDAPVGEEEAPAKYVQDNIQLHGQQVARILLQENGHIYVCGDAKNMAKDV
Sbjct: 601 ILTHLKVSFSRDAPVGEEEAPAKYVQDNIQLHGQQVARILLQENGHIYVCGDAKNMAKDV 660
Query: 661 HDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIWS 698
HDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIWS
Sbjct: 661 HDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIWS 698
>gi|169790956 methionine synthase reductase isoform 2 [Homo sapiens]
Length = 725
Score = 1400 bits (3623), Expect = 0.0
Identities = 698/698 (100%), Positives = 698/698 (100%)
Query: 1 MRRFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTT 60
MRRFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTT
Sbjct: 28 MRRFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTT 87
Query: 61 GTGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGA 120
GTGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGA
Sbjct: 88 GTGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGA 147
Query: 121 RHFYDTGHADDCVGLELVVEPWIAGLWPALRKHFRSSRGQEEISGALPVASPASSRTDLV 180
RHFYDTGHADDCVGLELVVEPWIAGLWPALRKHFRSSRGQEEISGALPVASPASSRTDLV
Sbjct: 148 RHFYDTGHADDCVGLELVVEPWIAGLWPALRKHFRSSRGQEEISGALPVASPASSRTDLV 207
Query: 181 KSELLHIESQVELLRFDDSGRKDSEVLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASL 240
KSELLHIESQVELLRFDDSGRKDSEVLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASL
Sbjct: 208 KSELLHIESQVELLRFDDSGRKDSEVLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASL 267
Query: 241 NIPGLPPEYLQVHLQESLGQEESQVSVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDI 300
NIPGLPPEYLQVHLQESLGQEESQVSVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDI
Sbjct: 268 NIPGLPPEYLQVHLQESLGQEESQVSVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDI 327
Query: 301 SNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQHI 360
SNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQHI
Sbjct: 328 SNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQHI 387
Query: 361 PAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRDA 420
PAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRDA
Sbjct: 388 PAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRDA 447
Query: 421 CACLLDLLLAFPSCQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTAT 480
CACLLDLLLAFPSCQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTAT
Sbjct: 448 CACLLDLLLAFPSCQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTAT 507
Query: 481 TEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPDDPSIPI 540
TEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPDDPSIPI
Sbjct: 508 TEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPDDPSIPI 567
Query: 541 IMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKELRHFLKHG 600
IMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKELRHFLKHG
Sbjct: 568 IMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKELRHFLKHG 627
Query: 601 ILTHLKVSFSRDAPVGEEEAPAKYVQDNIQLHGQQVARILLQENGHIYVCGDAKNMAKDV 660
ILTHLKVSFSRDAPVGEEEAPAKYVQDNIQLHGQQVARILLQENGHIYVCGDAKNMAKDV
Sbjct: 628 ILTHLKVSFSRDAPVGEEEAPAKYVQDNIQLHGQQVARILLQENGHIYVCGDAKNMAKDV 687
Query: 661 HDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIWS 698
HDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIWS
Sbjct: 688 HDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIWS 725
>gi|40254422 nitric oxide synthase 3 isoform 1 [Homo sapiens]
Length = 1203
Score = 219 bits (558), Expect = 7e-57
Identities = 200/746 (26%), Positives = 311/746 (41%), Gaps = 161/746 (21%)
Query: 6 LLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTTGTGDP 65
+LY ++ G+A++ A+++ + F + C+ E D L+ ET LVV ST G GDP
Sbjct: 522 ILYGSETGRAQSYAQQL-GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVT-STFGNGDP 579
Query: 66 PDTARKFVKEIQNQTLPVDF---------------------------------------- 85
P+ F + + P +
Sbjct: 580 PENGESFAAALMEMSGPYNSSPRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSA 639
Query: 86 --FAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGARHFYDTGHADDCVGLELVVEPWI 143
LR+ + GLG Y +FC + +D RL+ELG G D+ G E W
Sbjct: 640 GALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWA 699
Query: 144 AGLWPALRKHFRSSRGQEEISGALPVASPASSRTDLVKSELLHIESQVELLRFDDSGRKD 203
+ A + F G++ + A + SP S K + + +Q E L+
Sbjct: 700 QAAFQAACETF--CVGEDAKAAARDIFSPKRS----WKRQRYRLSAQAEGLQL------- 746
Query: 204 SEVLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASLNIPGLPPEYLQVHLQESLGQEES 263
+PGL + VH ++
Sbjct: 747 --------------------------------------LPGL----IHVHRRKMF----- 759
Query: 264 QVSVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDISNTD-FSYQPGDAFSVICPNSDS 322
Q ++ S + L ++ + + T+LV LD + YQPGD V PN
Sbjct: 760 QATIRSVE-----------NLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPG 808
Query: 323 EVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQHIPAG---------CSLQFIFTWC 373
V++LL R++ + + +KG+ P P G C+L+ T+
Sbjct: 809 LVEALLSRVEDPPAPTE----PVAVEQLEKGS--PGGPPPGWVRDPRLPPCTLRQALTFF 862
Query: 374 LEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRDACACLLDLLLAFPS 433
L+I + P LR L + E++ L+ L Q Y + C LL++L FPS
Sbjct: 863 LDITSPPSPQLLRLLSTLAEEPREQQELEAL--SQDPRRYEEWKWFRCPTLLEVLEQFPS 920
Query: 434 CQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTATTEVLRKGVCTGWL 493
P LLL LP LQPR YS +S+ HPG++H ++ + + L GVC+ WL
Sbjct: 921 VALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVLAYRTQDGLGPLHYGVCSTWL 980
Query: 494 ALLVASVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPDDPSIPIIMVGPGTGIAPFI 553
S L+P + R SF LP DPS+P I+VGPGTGIAPF
Sbjct: 981 -----SQLKP-------------GDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFR 1022
Query: 554 GFLQHREKLQEQHPDG-NFGAMWLFFGCRHKDRDYLFRKELRHFLKHGILTHLKVSFSRD 612
GF Q E+L + G M L FGCR D+L+R E+++ + G+ + +FSR
Sbjct: 1023 GFWQ--ERLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSR- 1079
Query: 613 APVGEEEAPAKYVQDNIQLH-GQQVARILLQENGHIYVCGDAKNMAKDVHDALVQIISKE 671
E + P YVQD ++ +V R+L E GH++VCGD MA +V + +I++ E
Sbjct: 1080 ----EPDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDV-TMATNVLQTVQRILATE 1134
Query: 672 VGVEKLEAMKTLATLKEEKRYLQDIW 697
+E EA + L++++RY +DI+
Sbjct: 1135 GDMELDEAGDVIGVLRDQQRYHEDIF 1160
>gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens]
Length = 1434
Score = 218 bits (556), Expect = 1e-56
Identities = 199/740 (26%), Positives = 313/740 (42%), Gaps = 149/740 (20%)
Query: 6 LLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTTGTGDP 65
+LYAT+ G+++A A+ +CE H F A + + E D L+ ET LVV ST G GDP
Sbjct: 762 ILYATETGKSQAYAKTLCE-IFKHAFDAKVMSMEEYDIVHLEHETLVLVVT-STFGNGDP 819
Query: 66 PDTARKF------------VKEIQNQTLPVDF---------------------------- 85
P+ KF V+E + ++ V F
Sbjct: 820 PENGEKFGCALMEMRHPNSVQE-ERKSYKVRFNSVSSYSDSQKSSGDGPDLRDNFESAGP 878
Query: 86 FAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGARHFYDTGHADDCVGLELVVEPWIAG 145
A++R+ + GLG Y +FC G +D L+ELG D+ G E W
Sbjct: 879 LANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEAFRTWA-- 936
Query: 146 LWPALRKHFRSSRGQEEISGALPVASPASSRTDLVKSELLHIESQVELLRFDDSGRKDSE 205
+K F+++ ++ + V + + ++S +
Sbjct: 937 -----KKVFKAA------------------------CDVFCVGDDVNIEKANNSLISNDR 967
Query: 206 VLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASLNIPGLPPEYLQVHLQESLGQEESQV 265
K+N F + P L+Q N+ +V L ++ Q
Sbjct: 968 SWKRNK------------FRLTFVAEAPELTQGLSNV-----HKKRVSAARLLSRQNLQS 1010
Query: 266 SVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDISNTDFSYQPGDAFSVICPNSDSEVQ 325
+S +F V+L TN + + YQPGD V N + V
Sbjct: 1011 PKSSRSTIF-------VRLHTN-------------GSQELQYQPGDHLGVFPGNHEDLVN 1050
Query: 326 SLLQRLQLEDKREHCVLLKIKADTKKKGA-------TLPQHIPAGCSLQFIFTWCLEIRA 378
+L++RL ED ++K++ ++ A T +P C++ F + L+I
Sbjct: 1051 ALIERL--EDAPPVNQMVKVELLEERNTALGVISNWTDELRLPP-CTIFQAFKYYLDITT 1107
Query: 379 IPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRDACACLLDLLLAFPSCQPPL 438
P L+ + EK+RL L +G +Y + ++++L FPS Q P
Sbjct: 1108 PPTPLQLQQFASLATSEKEKQRL--LVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPA 1165
Query: 439 SLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTATTEVLRKGVCTGWLALLVA 498
+LLL L LQPR YS +SS +P ++H IV + + + GVC+ WL + A
Sbjct: 1166 TLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQA 1225
Query: 499 SVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPDDPSIPIIMVGPGTGIAPFIGFLQH 558
L P R SFHLP +P +P I+VGPGTGIAPF F Q
Sbjct: 1226 DELVP------------------CFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQ 1267
Query: 559 REKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKELRHFLKHGILTHLKVSFSRDAPVGEE 618
R+ QH N M L FGCR D+++R+E G+ L ++SR E
Sbjct: 1268 RQ-FDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSR-----EP 1321
Query: 619 EAPAKYVQDNIQLH-GQQVARILLQENGHIYVCGDAKNMAKDVHDALVQIISKEVGVEKL 677
+ P KYVQD +Q + V R L ++ GHIYVCGD MA DV A+ +I++++ +
Sbjct: 1322 DKPKKYVQDILQEQLAESVYRALKEQGGHIYVCGDV-TMAADVLKAIQRIMTQQGKLSAE 1380
Query: 678 EAMKTLATLKEEKRYLQDIW 697
+A ++ ++++ RY +DI+
Sbjct: 1381 DAGVFISRMRDDNRYHEDIF 1400
>gi|127139033 cytochrome P450 reductase [Homo sapiens]
Length = 680
Score = 211 bits (536), Expect = 2e-54
Identities = 147/448 (32%), Positives = 227/448 (50%), Gaps = 37/448 (8%)
Query: 258 LGQEESQVSVTSADPVFQVPISKAVQLTTNDAI-----KTTLLVELDISNTDFSYQPGDA 312
+G+ S + P F +TTN + + + +ELDIS++ Y+ GD
Sbjct: 263 MGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDH 322
Query: 313 FSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQHIPAGCSLQFIFTW 372
+V P +DS + + L ++ D L + ++ KK P S + T+
Sbjct: 323 VAVY-PANDSALVNQLGKILGADLDVVMSLNNLDEESNKK-----HPFPCPTSYRTALTY 376
Query: 373 CLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAAD--YSRFVRDACACLLDLLLA 430
L+I P+ L L Y S+ +E+ L+++ S G Y +V +A +L +L
Sbjct: 377 YLDITNPPRTNVLYELAQYASEPSEQELLRKMASSSGEGKELYLSWVVEARRHILAILQD 436
Query: 431 FPSCQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTATTEVLRKGVCT 490
PS +PP+ L E LP+LQ R YS ASSS HP +H +VE+ + A + KGV T
Sbjct: 437 CPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVVVEYETKAGR--INKGVAT 494
Query: 491 GWLALLVASVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPDDPSIPIIMVGPGTGIA 550
WL + E+ G+AL P + F LP + P+IMVGPGTG+A
Sbjct: 495 NWLRAK---------EPAGENGGRALVPMFV----RKSQFRLPFKATTPVIMVGPGTGVA 541
Query: 551 PFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKELRHFLKHGILTHLKVSFS 610
PFIGF+Q R L++Q + G L++GCR D DYL+R+EL F + G LT L V+FS
Sbjct: 542 PFIGFIQERAWLRQQGKE--VGETLLYYGCRRSDEDYLYREELAQFHRDGALTQLNVAFS 599
Query: 611 RDAPVGEEEAPAKYVQDNIQLHGQQVARILLQENGHIYVCGDAKNMAKDVHDALVQIISK 670
R E++ YVQ ++ + + + L++ HIYVCGDA+NMA+DV + I+++
Sbjct: 600 R------EQSHKVYVQHLLKQDREHLWK-LIEGGAHIYVCGDARNMARDVQNTFYDIVAE 652
Query: 671 EVGVEKLEAMKTLATLKEEKRYLQDIWS 698
+E +A+ + L + RY D+WS
Sbjct: 653 LGAMEHAQAVDYIKKLMTKGRYSLDVWS 680
Score = 81.3 bits (199), Expect = 3e-15
Identities = 51/167 (30%), Positives = 82/167 (49%), Gaps = 7/167 (4%)
Query: 2 RRFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKT----ETAPLVVVV 57
R ++ Y +Q G A+ A + + A +G E D DL + + A +V +
Sbjct: 81 RNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDNALVVFCM 140
Query: 58 STTGTGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQE 117
+T G GDP D A+ F +Q + + + +++ + GLG+ Y +F GK +DKRL++
Sbjct: 141 ATYGEGDPTDNAQDFYDWLQETDVDL---SGVKFAVFGLGNKTYEHFNAMGKYVDKRLEQ 197
Query: 118 LGARHFYDTGHADDCVGLELVVEPWIAGLWPALRKHFRSSRGQEEIS 164
LGA+ ++ G DD LE W WPA+ +HF EE S
Sbjct: 198 LGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEHFGVEATGEESS 244
>gi|24041029 nitric oxide synthase 2A [Homo sapiens]
Length = 1153
Score = 188 bits (477), Expect = 2e-47
Identities = 138/459 (30%), Positives = 221/459 (48%), Gaps = 33/459 (7%)
Query: 241 NIPGLPPEYLQVHLQESLGQEESQVSVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDI 300
N+ P Y V + L ++ +S A VF + + L + + + T+LVEL
Sbjct: 701 NVTWDPHHYRLVQDSQPLDLSKA-LSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSC 759
Query: 301 SNTD-FSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQH 359
+ +Y PG+ V N + VQ +L+R+ ++ H + D +
Sbjct: 760 EDGQGLNYLPGEHLGVCPGNQPALVQGILERV-VDGPTPHQTVRLEALDESGSYWVSDKR 818
Query: 360 IPAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRD 419
+P CSL T+ L+I P + L+ L ++ E++RL+ LC ++YS++
Sbjct: 819 LPP-CSLSQALTYFLDITTPPTQLLLQKLAQVATEEPERQRLEALCQP---SEYSKWKFT 874
Query: 420 ACACLLDLLLAFPSCQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTA 479
L++L FPS + LL LP L+PR YS +SS P ++H +V + +
Sbjct: 875 NSPTFLEVLEEFPSLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRD 934
Query: 480 TTEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPDDPSIP 539
L GVC+ WL + L+P + R + FHLP+DPS P
Sbjct: 935 GQGPLHHGVCSTWL-----NSLKPQ-------------DPVPCFVRNASGFHLPEDPSHP 976
Query: 540 IIMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKELRHFLKH 599
I++GPGTGIAPF F Q R QH G M L FGCR D D+++++E+ +
Sbjct: 977 CILIGPGTGIAPFRSFWQQRLH-DSQHKGVRGGRMTLVFGCRRPDEDHIYQEEMLEMAQK 1035
Query: 600 GILTHLKVSFSRDAPVGEEEAPAKYVQDNI-QLHGQQVARILLQENGHIYVCGDAKNMAK 658
G+L + ++SR P YVQD + Q +V R+L +E GH+YVCGD + MA+
Sbjct: 1036 GVLHAVHTAYSR-----LPGKPKVYVQDILRQQLASEVLRVLHKEPGHLYVCGDVR-MAR 1089
Query: 659 DVHDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIW 697
DV L Q+++ ++ + + + LK +KRY +DI+
Sbjct: 1090 DVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHEDIF 1128
Score = 62.8 bits (151), Expect = 1e-09
Identities = 52/169 (30%), Positives = 76/169 (44%), Gaps = 22/169 (13%)
Query: 3 RFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKT--ETAPLVVVVSTT 60
R +L+AT+ G+++A+A ++ F+ + C+ DKY L E L+VV ST
Sbjct: 538 RVTILFATETGKSEALAWDL-GALFSCAFNPKVVCM---DKYRLSCLEEERLLLVVTSTF 593
Query: 61 GTGDPPDTARKF------VKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKR 114
G GD P K +KE+ N+ RY + GLG S Y FC ID++
Sbjct: 594 GNGDCPGNGEKLKKSLFMLKELNNK---------FRYAVFGLGSSMYPRFCAFAHDIDQK 644
Query: 115 LQELGARHFYDTGHADDCVGLELVVEPWIAGLWPALRKHFRSSRGQEEI 163
L LGA G D+ G E W + A + F RG++ I
Sbjct: 645 LSHLGASQLTPMGEGDELSGQEDAFRSWAVQTFKAACETF-DVRGKQHI 692
>gi|221316705 NADPH dependent diflavin oxidoreductase 1 isoform a
[Homo sapiens]
Length = 606
Score = 181 bits (458), Expect = 3e-45
Identities = 138/480 (28%), Positives = 230/480 (47%), Gaps = 48/480 (10%)
Query: 233 PPLSQASLNIPGLPPEYLQVHLQE--SLGQEESQVS------VTSADPVFQVPISKAVQL 284
P L++ +P LP ++ + LQE S G E +V+ S F P+ ++
Sbjct: 161 PGLTEIPPGVP-LPSKFTLLFLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRV 219
Query: 285 TTNDAIKTTLLVELDISNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLK 344
T + L+E DI + S+ GD + NS + VQ Q L L+ + +
Sbjct: 220 TGPSHFQDVRLIEFDILGSGISFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFML--- 276
Query: 345 IKADTKKKGATLPQHIPAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQEL 404
++ + P +P CS++ + + L+I ++P+++F L + E+ +L E
Sbjct: 277 ---QPREPDVSSPTRLPQPCSMRHLVSHYLDIASVPRRSFFELLACLSLHELEREKLLEF 333
Query: 405 CSKQGAADYSRFVRDACACLLDLLLAFP--SCQPPLSLLLEHLPKLQPRPYSCASSSLFH 462
S QG + + +L++L FP + P LL+ +P ++PR +S ASS L H
Sbjct: 334 SSAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTH 393
Query: 463 PGKLHFVFNIVEFLSTATTEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKA-LAPKIS 521
P +L + +V+F + R+G+C+ WLA L D G+ + +
Sbjct: 394 PSRLQILVAVVQFQTRLKEP--RRGLCSSWLASL--------------DPGQGPVRVPLW 437
Query: 522 ISPRTTNSFHLPDDPSIPIIMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCR 581
+ P S P+ P P+IMVGPGTG+APF +Q R Q GNF LFFGCR
Sbjct: 438 VRP---GSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVA---QGQTGNF----LFFGCR 487
Query: 582 HKDRDYLFRKELRHFLKHGILTHLKVSFSRDAPVGEEEAPAK---YVQDNIQLHGQQVAR 638
+D+D+ + E + K LT L +FSR+ P A + YVQ ++ G V
Sbjct: 488 WRDQDFYWEAEWQELEKRDCLT-LIPAFSREQPPALFSALQEQKVYVQHRLRELGSLVWE 546
Query: 639 ILLQENGHIYVCGDAKNMAKDVHDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIWS 698
+L ++ + Y+ G+AK+M DV +AL+ I +E G+ +A LA L++ +R+ + W+
Sbjct: 547 LLDRQGAYFYLAGNAKSMPADVSEALMSIFQEEGGLCSPDAAAYLARLQQTRRFQTETWA 606
Score = 77.0 bits (188), Expect = 5e-14
Identities = 51/172 (29%), Positives = 82/172 (47%), Gaps = 5/172 (2%)
Query: 3 RFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVV-STTG 61
+ L+L+ +Q G A+ ++E + +A + + +L E PLV+ V +TTG
Sbjct: 5 QLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINE--PLVIFVCATTG 62
Query: 62 TGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGAR 121
GDPPD + F + I + LP + + +LGLGDS Y F K + +RL +LG
Sbjct: 63 QGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGS 122
Query: 122 HFYDTGHADDC--VGLELVVEPWIAGLWPALRKHFRSSRGQEEISGALPVAS 171
DD +G + V+PW+ LW + + G EI +P+ S
Sbjct: 123 ALLPVCLGDDQHELGPDAAVDPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPS 174
>gi|7657393 NADPH dependent diflavin oxidoreductase 1 isoform b
[Homo sapiens]
Length = 597
Score = 180 bits (456), Expect = 5e-45
Identities = 137/477 (28%), Positives = 228/477 (47%), Gaps = 51/477 (10%)
Query: 233 PPLSQASLNIPGLPPEYLQVHLQE--SLGQEESQVS------VTSADPVFQVPISKAVQL 284
P L++ +P LP ++ + LQE S G E +V+ S F P+ ++
Sbjct: 161 PGLTEIPPGVP-LPSKFTLLFLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRV 219
Query: 285 TTNDAIKTTLLVELDISNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLK 344
T + L+E DI + S+ GD + NS + VQ Q L L+ + +
Sbjct: 220 TGPSHFQDVRLIEFDILGSGISFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFML--- 276
Query: 345 IKADTKKKGATLPQHIPAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQEL 404
++ + P +P CS++ + + L+I ++P+++F L + E+ +L E
Sbjct: 277 ---QPREPDVSSPTRLPQPCSMRHLVSHYLDIASVPRRSFFELLACLSLHELEREKLLEF 333
Query: 405 CSKQGAADYSRFVRDACACLLDLLLAFP--SCQPPLSLLLEHLPKLQPRPYSCASSSLFH 462
S QG + + +L++L FP + P LL+ +P ++PR +S ASS L H
Sbjct: 334 SSAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTH 393
Query: 463 PGKLHFVFNIVEFLSTATTEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKA-LAPKIS 521
P +L + +V+F + R+G+C+ WLA L D G+ + +
Sbjct: 394 PSRLQILVAVVQFQTRLKEP--RRGLCSSWLASL--------------DPGQGPVRVPLW 437
Query: 522 ISPRTTNSFHLPDDPSIPIIMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCR 581
+ P S P+ P P+IMVGPGTG+APF +Q R Q GNF LFFGCR
Sbjct: 438 VRP---GSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVA---QGQTGNF----LFFGCR 487
Query: 582 HKDRDYLFRKELRHFLKHGILTHLKVSFSRDAPVGEEEAPAKYVQDNIQLHGQQVARILL 641
+D+D+ + E + K LT L +FSR E+ YVQ ++ G V +L
Sbjct: 488 WRDQDFYWEAEWQELEKRDCLT-LIPAFSR------EQEQKVYVQHRLRELGSLVWELLD 540
Query: 642 QENGHIYVCGDAKNMAKDVHDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIWS 698
++ + Y+ G+AK+M DV +AL+ I +E G+ +A LA L++ +R+ + W+
Sbjct: 541 RQGAYFYLAGNAKSMPADVSEALMSIFQEEGGLCSPDAAAYLARLQQTRRFQTETWA 597
Score = 77.0 bits (188), Expect = 5e-14
Identities = 51/172 (29%), Positives = 82/172 (47%), Gaps = 5/172 (2%)
Query: 3 RFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVV-STTG 61
+ L+L+ +Q G A+ ++E + +A + + +L E PLV+ V +TTG
Sbjct: 5 QLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINE--PLVIFVCATTG 62
Query: 62 TGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGAR 121
GDPPD + F + I + LP + + +LGLGDS Y F K + +RL +LG
Sbjct: 63 QGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGS 122
Query: 122 HFYDTGHADDC--VGLELVVEPWIAGLWPALRKHFRSSRGQEEISGALPVAS 171
DD +G + V+PW+ LW + + G EI +P+ S
Sbjct: 123 ALLPVCLGDDQHELGPDAAVDPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPS 174
>gi|221316709 NADPH dependent diflavin oxidoreductase 1 isoform c
[Homo sapiens]
Length = 590
Score = 166 bits (421), Expect = 5e-41
Identities = 134/477 (28%), Positives = 222/477 (46%), Gaps = 58/477 (12%)
Query: 233 PPLSQASLNIPGLPPEYLQVHLQE--SLGQEESQVS------VTSADPVFQVPISKAVQL 284
P L++ +P LP ++ + LQE S G E +V+ S F P+ ++
Sbjct: 161 PGLTEIPPGVP-LPSKFTLLFLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRV 219
Query: 285 TTNDAIKTTLLVELDISNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLK 344
T + L+E DI + S+ GD + NS + VQ Q L L+ + +
Sbjct: 220 TGPSHFQDVRLIEFDILGSGISFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFML--- 276
Query: 345 IKADTKKKGATLPQHIPAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQEL 404
++ + P +P CS++ + + L+I ++P+++F L + E+ +L E
Sbjct: 277 ---QPREPDVSSPTRLPQPCSMRHLVSHYLDIASVPRRSFFELLACLSLHELEREKLLEF 333
Query: 405 CSKQGAADYSRFVRDACACLLDLLLAFP--SCQPPLSLLLEHLPKLQPRPYSCASSSLFH 462
S QG + + +L++L FP + P LL+ +P ++PR +S ASS L
Sbjct: 334 SSAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLIL 393
Query: 463 PGKLHFVFNIVEFLSTATTEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKA-LAPKIS 521
+ F + E R+G+C+ WLA L D G+ + +
Sbjct: 394 VAVVQFQTRLKE---------PRRGLCSSWLASL--------------DPGQGPVRVPLW 430
Query: 522 ISPRTTNSFHLPDDPSIPIIMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCR 581
+ P S P+ P P+IMVGPGTG+APF +Q R Q GNF LFFGCR
Sbjct: 431 VRP---GSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVA---QGQTGNF----LFFGCR 480
Query: 582 HKDRDYLFRKELRHFLKHGILTHLKVSFSRDAPVGEEEAPAKYVQDNIQLHGQQVARILL 641
+D+D+ + E + K LT L +FSR E+ YVQ ++ G V +L
Sbjct: 481 WRDQDFYWEAEWQELEKRDCLT-LIPAFSR------EQEQKVYVQHRLRELGSLVWELLD 533
Query: 642 QENGHIYVCGDAKNMAKDVHDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIWS 698
++ + Y+ G+AK+M DV +AL+ I +E G+ +A LA L++ +R+ + W+
Sbjct: 534 RQGAYFYLAGNAKSMPADVSEALMSIFQEEGGLCSPDAAAYLARLQQTRRFQTETWA 590
Score = 77.0 bits (188), Expect = 5e-14
Identities = 51/172 (29%), Positives = 82/172 (47%), Gaps = 5/172 (2%)
Query: 3 RFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVV-STTG 61
+ L+L+ +Q G A+ ++E + +A + + +L E PLV+ V +TTG
Sbjct: 5 QLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINE--PLVIFVCATTG 62
Query: 62 TGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGAR 121
GDPPD + F + I + LP + + +LGLGDS Y F K + +RL +LG
Sbjct: 63 QGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGS 122
Query: 122 HFYDTGHADDC--VGLELVVEPWIAGLWPALRKHFRSSRGQEEISGALPVAS 171
DD +G + V+PW+ LW + + G EI +P+ S
Sbjct: 123 ALLPVCLGDDQHELGPDAAVDPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPS 174
>gi|221316707 NADPH dependent diflavin oxidoreductase 1 isoform d
[Homo sapiens]
Length = 521
Score = 145 bits (366), Expect = 1e-34
Identities = 117/408 (28%), Positives = 188/408 (46%), Gaps = 50/408 (12%)
Query: 244 GLPPEYLQVHLQE--SLGQEESQVS------VTSADPVFQVPISKAVQLTTNDAIKTTLL 295
GLP ++ + LQE S G E +V+ S F P+ ++T + L
Sbjct: 137 GLPSKFTLLFLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRL 196
Query: 296 VELDISNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGAT 355
+E DI + S+ GD + NS + VQ Q L L+ + + ++ +
Sbjct: 197 IEFDILGSGISFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFML------QPREPDVS 250
Query: 356 LPQHIPAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSR 415
P +P CS++ + + L+I ++P+++F L + E+ +L E S QG +
Sbjct: 251 SPTRLPQPCSMRHLVSHYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFE 310
Query: 416 FVRDACACLLDLLLAFP--SCQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIV 473
+ +L++L FP + P LL+ +P ++PR +S ASS L HP +L + +V
Sbjct: 311 YCNRPRRTILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVV 370
Query: 474 EFLSTATTEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKA-LAPKISISPRTTNSFHL 532
+F + R+G+C+ WLA L D G+ + + + P S
Sbjct: 371 QFQTRLKEP--RRGLCSSWLASL--------------DPGQGPVRVPLWVRP---GSLAF 411
Query: 533 PDDPSIPIIMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKE 592
P+ P P+IMVGPGTG+APF +Q R Q GNF LFFGCR +D+D+ + E
Sbjct: 412 PETPDTPVIMVGPGTGVAPFRAAIQER---VAQGQTGNF----LFFGCRWRDQDFYWEAE 464
Query: 593 LRHFLKHGILTHLKVSFSRDAPVGEEEAPAKYVQDNIQLHGQQVARIL 640
+ K LT L +FSR E+ YVQ ++ G V +L
Sbjct: 465 WQELEKRDCLT-LIPAFSR------EQEQKVYVQHRLRELGSLVWELL 505
Score = 62.4 bits (150), Expect = 1e-09
Identities = 40/130 (30%), Positives = 63/130 (48%), Gaps = 3/130 (2%)
Query: 3 RFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVV-STTG 61
+ L+L+ +Q G A+ ++E + +A + + +L E PLV+ V +TTG
Sbjct: 5 QLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINE--PLVIFVCATTG 62
Query: 62 TGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGAR 121
GDPPD + F + I + LP + + +LGLGDS Y F K + +RL +LG
Sbjct: 63 QGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGS 122
Query: 122 HFYDTGHADD 131
DD
Sbjct: 123 ALLPVCLGDD 132
>gi|50726981 radical S-adenosyl methionine and flavodoxin domains 1
[Homo sapiens]
Length = 732
Score = 46.6 bits (109), Expect = 8e-05
Identities = 38/134 (28%), Positives = 57/134 (42%), Gaps = 9/134 (6%)
Query: 6 LLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAP----LVVVVSTTG 61
+ Y +Q G AK A + E + + E D D E V +V+T
Sbjct: 81 IFYGSQTGTAKGFATVLAEAVTSLDLPVAIINLKEYDPDDHLIEEVTSKNVCVFLVATYT 140
Query: 62 TGDPPDTARKFVKEIQNQTLPVDF----FAHLRYGLLGLGDSEY-TYFCNGGKIIDKRLQ 116
G P ++A F K ++ ++ F +RY + GLG+S Y ++F GK +DK L
Sbjct: 141 DGLPTESAEWFCKWLEEASIDFRFGKTYLKGMRYAVFGLGNSAYASHFNKVGKNVDKWLW 200
Query: 117 ELGARHFYDTGHAD 130
LGA G D
Sbjct: 201 MLGAHRVMSRGEGD 214
>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
Length = 4069
Score = 39.3 bits (90), Expect = 0.012
Identities = 41/174 (23%), Positives = 75/174 (43%), Gaps = 20/174 (11%)
Query: 181 KSELLHIESQVELLRFDDSGRKDSEVLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASL 240
K E LH E V L+ D+ + E + + A +++ V + FE R + + +++
Sbjct: 3617 KMEFLH-EQMVHFLQSMDTAKDTLETIVREAEELDEA-VFLTSFEEINERLLSAM-ESTA 3673
Query: 241 NIPGLPPEYLQVHLQESLGQEESQVSVTSADPVFQVPISKAVQLTT---NDAIKTTLLVE 297
++ +P + SL + S S + QV + + +L N A TT+ V
Sbjct: 3674 SLEKMPAAF-------SLFEHYDDSSARSDQMLKQVAVPQPPRLEPQEPNSATSTTIAVY 3726
Query: 298 LDISNTDFSYQPGDAFSVIC---PNSDSEVQSLLQRLQLEDKREHCVLLKIKAD 348
++ D D+F V C P D EV L++ +L K +C+ ++ D
Sbjct: 3727 WSMNKEDVI----DSFQVYCMEEPQDDQEVNELVEEYRLTVKESYCIFEDLEPD 3776
>gi|231571329 nitric oxide synthase 3 isoform 3 [Homo sapiens]
Length = 614
Score = 38.9 bits (89), Expect = 0.016
Identities = 22/67 (32%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
Query: 6 LLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTTGTGDP 65
+LY ++ G+A++ A+++ + F + C+ E D L+ ET LVV ST G GDP
Sbjct: 522 ILYGSETGRAQSYAQQL-GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVT-STFGNGDP 579
Query: 66 PDTARKF 72
P+ ++
Sbjct: 580 PENGERW 586
>gi|231571356 nitric oxide synthase 3 isoform 4 [Homo sapiens]
Length = 629
Score = 37.7 bits (86), Expect = 0.036
Identities = 22/62 (35%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Query: 6 LLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTTGTGDP 65
+LY ++ G+A++ A+++ + F + C+ E D L+ ET LVV ST G GDP
Sbjct: 522 ILYGSETGRAQSYAQQL-GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVT-STFGNGDP 579
Query: 66 PD 67
P+
Sbjct: 580 PE 581
>gi|231571314 nitric oxide synthase 3 isoform 2 [Homo sapiens]
Length = 596
Score = 37.7 bits (86), Expect = 0.036
Identities = 22/62 (35%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Query: 6 LLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTTGTGDP 65
+LY ++ G+A++ A+++ + F + C+ E D L+ ET LVV ST G GDP
Sbjct: 522 ILYGSETGRAQSYAQQL-GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVT-STFGNGDP 579
Query: 66 PD 67
P+
Sbjct: 580 PE 581
>gi|55742678 glucocorticoid induced transcript 1 [Homo sapiens]
Length = 547
Score = 37.7 bits (86), Expect = 0.036
Identities = 36/151 (23%), Positives = 67/151 (44%), Gaps = 27/151 (17%)
Query: 135 LELVVEPWIAGLWPA-LRKHFRSSR-----------GQEEISGALPVASPASSRTDLVKS 182
L+ + P++ G WP H+ S +E S + D +K
Sbjct: 173 LDTITGPYLTGQWPRDPHVHYPSCMKDKATQTPSCWAEEGAEKRSHQRSASWGSADQLKE 232
Query: 183 ELLHIESQVELLRFDDSGRKDSEVLKQNAVNSNQSNVVIEDFESSLTRSVP-PLSQASL- 240
++ + Q++ R S R E +Q+ ++ N ++ I +++ +RSVP PLS S+
Sbjct: 233 QIAKLRQQLQ--RSKQSSRHSKEKDRQSPLHGN--HITISHTQATGSRSVPMPLSNISVP 288
Query: 241 ---------NIPGLPPEYLQVHLQESLGQEE 262
N+ G+ PE +V ++E+ G+EE
Sbjct: 289 KSSVSRVPCNVEGISPELEKVFIKENNGKEE 319
>gi|113722133 senataxin [Homo sapiens]
Length = 2677
Score = 34.3 bits (77), Expect = 0.40
Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 14/95 (14%)
Query: 197 DDSGRKDSEVLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASLNIPGLPPEYLQVHLQE 256
+D R S V + ++N+ ++V DF+S R+ P S+ +
Sbjct: 1171 EDPVRPSSSVRNEGQSDTNKRDLVGNDFKSIDRRTSTPNSR--------------IQRAT 1216
Query: 257 SLGQEESQVSVTSADPVFQVPISKAVQLTTNDAIK 291
++ Q++S T +P+ +VP+SK + T +DA K
Sbjct: 1217 TVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKK 1251
>gi|116805344 proline rich, lacrimal 1 [Homo sapiens]
Length = 248
Score = 32.0 bits (71), Expect = 2.0
Identities = 23/114 (20%), Positives = 41/114 (35%), Gaps = 5/114 (4%)
Query: 243 PGLPPEYLQVHLQESLGQEESQVSVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDISN 302
P PP + + + E Q+++T+AD TT+ + K T+ +
Sbjct: 122 PPFPPIPFFLAIYLPISNPEPQINITTADTTITTNPPTTATATTSTSTKPTMTISSSTVP 181
Query: 303 TDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGATL 356
+ +P + S P + +E Q+ R H VLL T+
Sbjct: 182 ISSTPEPATSISAATPAASTE-----NTTQILANRPHTVLLNATVQVTTSNQTI 230
>gi|8923900 cytidine monophospho-N-acetylneuraminic acid synthetase
[Homo sapiens]
Length = 434
Score = 31.6 bits (70), Expect = 2.6
Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 7/51 (13%)
Query: 644 NGHIYVCGDAKN-MAKDVHDALVQIISKEVGV------EKLEAMKTLATLK 687
NGHIYV GD K ++ DV DA+ + K+ G+ E+ + +TL++LK
Sbjct: 288 NGHIYVSGDQKEIISYDVKDAIGISLLKKSGIEVRLISERACSKQTLSSLK 338
>gi|156416003 succinate dehydrogenase complex, subunit A,
flavoprotein precursor [Homo sapiens]
Length = 664
Score = 31.2 bits (69), Expect = 3.4
Identities = 23/104 (22%), Positives = 41/104 (39%)
Query: 232 VPPLSQASLNIPGLPPEYLQVHLQESLGQEESQVSVTSADPVFQVPISKAVQLTTNDAIK 291
+P L N+ G+P Y L+ GQ++ + + + A +L N +
Sbjct: 400 IPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLD 459
Query: 292 TTLLVELDISNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLED 335
+ + + S +PGD I PN+ E L +L+ D
Sbjct: 460 LVVFGRACALSIEESCRPGDKVPPIKPNAGEESVMNLDKLRFAD 503
>gi|153792230 hypothetical protein LOC57670 [Homo sapiens]
Length = 1884
Score = 31.2 bits (69), Expect = 3.4
Identities = 17/51 (33%), Positives = 28/51 (54%)
Query: 208 KQNAVNSNQSNVVIEDFESSLTRSVPPLSQASLNIPGLPPEYLQVHLQESL 258
K+ AVN ++ + + D + R V P+ +++ PGLP E L+ L SL
Sbjct: 98 KEVAVNDDEMDNFLPDTHWTTPRMVSPIQYITVSPPGLPREALEPMLTPSL 148
>gi|153251766 hypothetical protein LOC56181 isoform a [Homo sapiens]
Length = 292
Score = 30.4 bits (67), Expect = 5.8
Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 11/132 (8%)
Query: 158 RGQEEISGALPV-ASPASSRTDLVKSELLHIESQVELLRFDDSGRKDSEVLKQNAVNSNQ 216
RG EE AL A PA SRT ++ EL H+ SQ+ + D+ S L + ++
Sbjct: 108 RGSEERLLALKKPALPALSRTTELQDELSHLRSQIAKIVAADAA---SASLTPDFLSPGS 164
Query: 217 SNVVI------EDFESSLTRSVPPLS-QASLNIPGLPPEYLQVHLQESLGQEESQVSVTS 269
SNV F S+ + + ++ + + +P LP L + E + + +S
Sbjct: 165 SNVSSPLPCFGSSFHSTTSFVISDITEETEVEVPELPSVPLLCSASPECCKPEHKAACSS 224
Query: 270 ADPVFQVPISKA 281
++ V +SKA
Sbjct: 225 SEEDDCVSLSKA 236
>gi|153251748 hypothetical protein LOC56181 isoform a [Homo sapiens]
Length = 292
Score = 30.4 bits (67), Expect = 5.8
Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 11/132 (8%)
Query: 158 RGQEEISGALPV-ASPASSRTDLVKSELLHIESQVELLRFDDSGRKDSEVLKQNAVNSNQ 216
RG EE AL A PA SRT ++ EL H+ SQ+ + D+ S L + ++
Sbjct: 108 RGSEERLLALKKPALPALSRTTELQDELSHLRSQIAKIVAADAA---SASLTPDFLSPGS 164
Query: 217 SNVVI------EDFESSLTRSVPPLS-QASLNIPGLPPEYLQVHLQESLGQEESQVSVTS 269
SNV F S+ + + ++ + + +P LP L + E + + +S
Sbjct: 165 SNVSSPLPCFGSSFHSTTSFVISDITEETEVEVPELPSVPLLCSASPECCKPEHKAACSS 224
Query: 270 ADPVFQVPISKA 281
++ V +SKA
Sbjct: 225 SEEDDCVSLSKA 236
>gi|153251745 hypothetical protein LOC56181 isoform a [Homo sapiens]
Length = 292
Score = 30.4 bits (67), Expect = 5.8
Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 11/132 (8%)
Query: 158 RGQEEISGALPV-ASPASSRTDLVKSELLHIESQVELLRFDDSGRKDSEVLKQNAVNSNQ 216
RG EE AL A PA SRT ++ EL H+ SQ+ + D+ S L + ++
Sbjct: 108 RGSEERLLALKKPALPALSRTTELQDELSHLRSQIAKIVAADAA---SASLTPDFLSPGS 164
Query: 217 SNVVI------EDFESSLTRSVPPLS-QASLNIPGLPPEYLQVHLQESLGQEESQVSVTS 269
SNV F S+ + + ++ + + +P LP L + E + + +S
Sbjct: 165 SNVSSPLPCFGSSFHSTTSFVISDITEETEVEVPELPSVPLLCSASPECCKPEHKAACSS 224
Query: 270 ADPVFQVPISKA 281
++ V +SKA
Sbjct: 225 SEEDDCVSLSKA 236
>gi|19923907 oxidoreductase NAD-binding domain containing 1 [Homo
sapiens]
Length = 312
Score = 30.4 bits (67), Expect = 5.8
Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 5/65 (7%)
Query: 533 PDDPSIPIIMVGPGTGIAPFIGFLQH-REKLQEQHPDGN---FGAMWLFFGCRHKDRDYL 588
P D S ++++ G GI P + L+H + L+EQ N G + LF+ ++ + L
Sbjct: 165 PADASRNLVLIAGGVGINPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKNTS-ELL 223
Query: 589 FRKEL 593
F+K +
Sbjct: 224 FKKNI 228
>gi|38569394 inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase complex-associated protein [Homo sapiens]
Length = 1332
Score = 30.0 bits (66), Expect = 7.6
Identities = 31/137 (22%), Positives = 49/137 (35%), Gaps = 18/137 (13%)
Query: 151 RKHFRSSRGQEEISGALPVASPASSRTDLVKSELLHIESQVELLRFDDSGRKDSEVLKQN 210
+KH E L S T+ +K E+ HI + L FD+ GR
Sbjct: 1203 KKHSLKEGSPLEDLALLEALSEVVQNTENLKDEVYHILKVLFLFEFDEQGR--------- 1253
Query: 211 AVNSNQSNVVIEDFESSLTRSVPPL----SQASLNIPGLPPEYLQVHLQESLGQEESQVS 266
+ ED + RS+P + Q + P L P + S Q+++ V
Sbjct: 1254 -----ELQKAFEDTLQLMERSLPEIWTLTYQQNSATPVLGPNSTANSIMASYQQQKTSVP 1308
Query: 267 VTSADPVFQVPISKAVQ 283
V A+ I++ Q
Sbjct: 1309 VLDAELFIPPKINRRTQ 1325
>gi|110349721 titin isoform novex-3 [Homo sapiens]
Length = 5604
Score = 29.6 bits (65), Expect = 9.9
Identities = 17/46 (36%), Positives = 24/46 (52%)
Query: 65 PPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKI 110
P A K + IQ+QT+ AH R ++G D E ++ NG KI
Sbjct: 2073 PSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKI 2118
>gi|153791492 eukaryotic translation initiation factor 3, subunit
C-like [Homo sapiens]
Length = 914
Score = 29.6 bits (65), Expect = 9.9
Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 624 YVQDNIQLHGQQVARILLQENG-HIYVCGDAKNMAKDVHDALVQIISKEVGVEKLEAMKT 682
++QDNIQ H +IL + +C + + KD H+AL+ I S E L
Sbjct: 594 HLQDNIQ-HADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLL 652
Query: 683 LATLKEEKR 691
L +L+E +
Sbjct: 653 LRSLQERNQ 661
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 29.6 bits (65), Expect = 9.9
Identities = 17/46 (36%), Positives = 24/46 (52%)
Query: 65 PPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKI 110
P A K + IQ+QT+ AH R ++G D E ++ NG KI
Sbjct: 2073 PSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKI 2118
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 29.6 bits (65), Expect = 9.9
Identities = 17/46 (36%), Positives = 24/46 (52%)
Query: 65 PPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKI 110
P A K + IQ+QT+ AH R ++G D E ++ NG KI
Sbjct: 2027 PSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKI 2072
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,459,649
Number of Sequences: 37866
Number of extensions: 1278784
Number of successful extensions: 3324
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 3224
Number of HSP's gapped (non-prelim): 68
length of query: 698
length of database: 18,247,518
effective HSP length: 109
effective length of query: 589
effective length of database: 14,120,124
effective search space: 8316753036
effective search space used: 8316753036
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.