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Search of human proteins with 169646728
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
(452 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens] 921 0.0
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] 919 0.0
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] 919 0.0
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens] 726 0.0
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens] 721 0.0
gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo... 702 0.0
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo... 698 0.0
gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens] 657 0.0
gi|4504023 glycine receptor, beta [Homo sapiens] 374 e-103
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is... 292 5e-79
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso... 290 1e-78
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p... 290 1e-78
gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta pre... 289 4e-78
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso... 288 7e-78
gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2 is... 281 7e-76
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs... 276 2e-74
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s... 276 4e-74
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs... 276 4e-74
gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2 prec... 276 4e-74
gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1 [Hom... 275 5e-74
gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 275 6e-74
gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 275 6e-74
gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 275 6e-74
gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 275 6e-74
gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 275 6e-74
gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 275 6e-74
gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 p... 275 6e-74
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr... 274 1e-73
gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo s... 274 1e-73
gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor... 270 2e-72
>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
Length = 452
Score = 921 bits (2380), Expect = 0.0
Identities = 452/452 (100%), Positives = 452/452 (100%)
Query: 1 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA 60
MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA
Sbjct: 1 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA 60
Query: 61 RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD 120
RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD
Sbjct: 61 RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD 120
Query: 121 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP 180
PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP
Sbjct: 121 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP 180
Query: 181 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK 240
MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK
Sbjct: 181 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK 240
Query: 241 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 300
FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ
Sbjct: 241 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 300
Query: 301 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK 360
SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK
Sbjct: 301 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK 360
Query: 361 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT 420
EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT
Sbjct: 361 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT 420
Query: 421 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 452
ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK
Sbjct: 421 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 452
>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 919 bits (2375), Expect = 0.0
Identities = 450/452 (99%), Positives = 451/452 (99%)
Query: 1 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA 60
MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA
Sbjct: 1 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA 60
Query: 61 RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD 120
RIRPNFKGPPVNVTCNIFINSFGS+ ETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD
Sbjct: 61 RIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD 120
Query: 121 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP 180
PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP
Sbjct: 121 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP 180
Query: 181 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK 240
MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK
Sbjct: 181 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK 240
Query: 241 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 300
FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ
Sbjct: 241 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 300
Query: 301 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK 360
SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK
Sbjct: 301 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK 360
Query: 361 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT 420
EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT
Sbjct: 361 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT 420
Query: 421 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 452
ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK
Sbjct: 421 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 452
>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 919 bits (2375), Expect = 0.0
Identities = 450/452 (99%), Positives = 451/452 (99%)
Query: 1 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA 60
MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA
Sbjct: 1 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA 60
Query: 61 RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD 120
RIRPNFKGPPVNVTCNIFINSFGS+ ETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD
Sbjct: 61 RIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD 120
Query: 121 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP 180
PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP
Sbjct: 121 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP 180
Query: 181 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK 240
MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK
Sbjct: 181 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK 240
Query: 241 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 300
FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ
Sbjct: 241 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 300
Query: 301 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK 360
SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK
Sbjct: 301 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK 360
Query: 361 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT 420
EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT
Sbjct: 361 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT 420
Query: 421 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 452
ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK
Sbjct: 421 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 452
>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
Length = 449
Score = 726 bits (1875), Expect = 0.0
Identities = 357/422 (84%), Positives = 385/422 (91%), Gaps = 4/422 (0%)
Query: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 90
++ S + S +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM
Sbjct: 30 ETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 89
Query: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
DYRVNIFLRQ+WND RLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH+VTTDNK
Sbjct: 90 DYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNK 149
Query: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
LLRI KNG VLYSIRLTLTLSCPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW + PV
Sbjct: 150 LLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPV 209
Query: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
QVAEGLTLPQF+LKEEK+L YCTKHYNTGKFTCIEV+FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 210 QVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVI 269
Query: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 270 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 329
Query: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVK 390
ALLEYAAVNFVSRQHKE LR RR KR+NK+++V RESRF+F+ YGMG CLQ KDG K
Sbjct: 330 ALLEYAAVNFVSRQHKELLRFRR--KRKNKDDEV-RESRFSFTAYGMGPCLQAKDGMTPK 386
Query: 391 ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVH 450
P +P+ PK D ++K F+DRAK+IDTISRA FPLAFLIFNIFYW+ YKI+RHED+H
Sbjct: 387 G-PNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIH 445
Query: 451 KK 452
++
Sbjct: 446 QQ 447
>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
Length = 464
Score = 721 bits (1860), Expect = 0.0
Identities = 354/434 (81%), Positives = 383/434 (88%), Gaps = 13/434 (2%)
Query: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 90
++ S + S +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM
Sbjct: 30 ETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 89
Query: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
DYRVNIFLRQ+WND RLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH+VTTDNK
Sbjct: 90 DYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNK 149
Query: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
LLRI KNG VLYSIRLTLTLSCPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW + PV
Sbjct: 150 LLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPV 209
Query: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
QVAEGLTLPQF+LKEEK+L YCTKHYNTGKFTCIEV+FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 210 QVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVI 269
Query: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 270 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 329
Query: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKE------------EDVTRESRFNFSGYGMG 378
ALLEYAAVNFVSRQHKE LR RR++K + + +D RESRF+F+ YGMG
Sbjct: 330 ALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMG 389
Query: 379 HCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYW 438
CLQ KDG K P +P+ PK D ++K F+DRAK+IDTISRA FPLAFLIFNIFYW
Sbjct: 390 PCLQAKDGMTPKG-PNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYW 448
Query: 439 ITYKIIRHEDVHKK 452
+ YKI+RHED+H++
Sbjct: 449 VIYKILRHEDIHQQ 462
>gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 449
Score = 702 bits (1811), Expect = 0.0
Identities = 343/427 (80%), Positives = 376/427 (88%), Gaps = 7/427 (1%)
Query: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 90
++ + + + +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+CNIFINSFGSIAETTM
Sbjct: 25 EAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTM 84
Query: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
DYRVNIFLRQQWND RLAY+EYPDDSLDLDPSMLDSIWKPDLFFANEKGA+FH++TTDNK
Sbjct: 85 DYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNK 144
Query: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
LLRIS+NG VLYSIR+TLTL+CPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW G V
Sbjct: 145 LLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAV 204
Query: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
QVA+GLTLPQFILKEEK+L YCTKHYNTGKFTCIE +FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 205 QVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVI 264
Query: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
LSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 265 LSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 324
Query: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMG-HCLQVKDGTAV 389
ALLEYAAVNFVSRQHKE LR RR KR++ +ED E RFNFS YGMG CLQ KDG +V
Sbjct: 325 ALLEYAAVNFVSRQHKELLRFRR--KRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISV 382
Query: 390 K----ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIR 445
K + NP P P K + ++K F+ RAK+ID ISR FP+AFLIFN+FYWI YKI+R
Sbjct: 383 KGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVR 442
Query: 446 HEDVHKK 452
EDVH +
Sbjct: 443 REDVHNQ 449
>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 457
Score = 698 bits (1802), Expect = 0.0
Identities = 341/433 (78%), Positives = 375/433 (86%), Gaps = 11/433 (2%)
Query: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 90
++ + + + +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+CNIFINSFGSIAETTM
Sbjct: 25 EAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTM 84
Query: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
DYRVNIFLRQQWND RLAY+EYPDDSLDLDPSMLDSIWKPDLFFANEKGA+FH++TTDNK
Sbjct: 85 DYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNK 144
Query: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
LLRIS+NG VLYSIR+TLTL+CPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW G V
Sbjct: 145 LLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAV 204
Query: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
QVA+GLTLPQFILKEEK+L YCTKHYNTGKFTCIE +FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 205 QVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVI 264
Query: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
LSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 265 LSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 324
Query: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNK------EEDVTRESRFNFSGYGMG-HCLQV 383
ALLEYAAVNFVSRQHKE LR RR+++ +ED E RFNFS YGMG CLQ
Sbjct: 325 ALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQA 384
Query: 384 KDGTAVK----ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWI 439
KDG +VK + NP P P K + ++K F+ RAK+ID ISR FP+AFLIFN+FYWI
Sbjct: 385 KDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWI 444
Query: 440 TYKIIRHEDVHKK 452
YKI+R EDVH +
Sbjct: 445 IYKIVRREDVHNQ 457
>gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens]
Length = 417
Score = 657 bits (1694), Expect = 0.0
Identities = 324/396 (81%), Positives = 353/396 (89%), Gaps = 7/396 (1%)
Query: 23 RTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSF 82
R A K+ + +SG + SQ +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSF
Sbjct: 24 RVALAKE-EVKSGTKGSQPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSF 82
Query: 83 GSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANF 142
SI +TTMDYRVN+FLRQQWND RL+Y EYPDDSLDLDPSMLDSIWKPDLFFANEKGANF
Sbjct: 83 SSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSIWKPDLFFANEKGANF 142
Query: 143 HDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIF 202
H+VTTDNKLLRI KNG VLYSIRLTL LSC MDLKNFPMD+QTCTMQLESFGYTM DL+F
Sbjct: 143 HEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCTMQLESFGYTMKDLVF 202
Query: 203 EWLSDGP-VQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQM 261
EWL D P VQVAEGLTLPQFIL++EK+LG CTKHYNTGKFTCIEVKFHLERQMGYYLIQM
Sbjct: 203 EWLEDAPAVQVAEGLTLPQFILRDEKDLGCCTKHYNTGKFTCIEVKFHLERQMGYYLIQM 262
Query: 262 YIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWM 321
YIPSLLIVILSWVSFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVKAIDIWM
Sbjct: 263 YIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWM 322
Query: 322 AVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCL 381
AVCLLFVFAALLEYAA+NFVSRQHKEF+RLRRRQ+RQ EED+ +ESRF F GYG+GHCL
Sbjct: 323 AVCLLFVFAALLEYAAINFVSRQHKEFIRLRRRQRRQRLEEDIIQESRFYFRGYGLGHCL 382
Query: 382 QVKDGTAVKATPANPLPQPP----KDGDAIKKKFVD 413
Q +DG ++ + PQPP ++G+ +K +VD
Sbjct: 383 QARDGGPMEGSGIYS-PQPPAPLLREGETTRKLYVD 417
>gi|4504023 glycine receptor, beta [Homo sapiens]
Length = 497
Score = 374 bits (959), Expect = e-103
Identities = 220/484 (45%), Positives = 285/484 (58%), Gaps = 74/484 (15%)
Query: 25 AFCKDHDSRSGKQ-------PSQTLS------PSDFLDKLMGRTS-GYDARIRPNFKGPP 70
A+ K+ S+ GK PSQ + P++ ++ R YD RIRPNFKG P
Sbjct: 20 AYSKEKSSKKGKGKKKQYLCPSQQSAEDLARVPANSTSNILNRLLVSYDPRIRPNFKGIP 79
Query: 71 VNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAY-SEYP-DDSLDLDPSMLDSIW 128
V+V NIFINSFGSI ETTMDYRVNIFLRQ+WND RL S++ D+L +DP+M +W
Sbjct: 80 VDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLW 139
Query: 129 KPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTM 188
KPDLFFANEK ANFHDVT +N LL I ++G VL S+RL++TLSCP+DL FPMD Q C M
Sbjct: 140 KPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKM 199
Query: 189 QLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQF-ILKEEKELGYCTKHY-NTGKFTCIEV 246
QLESFGYT +DL F W S PVQ+ E + LPQF I KE+ E G CTK+Y TG +TC+EV
Sbjct: 200 QLESFGYTTDDLRFIWQSGDPVQL-EKIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEV 258
Query: 247 KFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRA 306
F L RQ+G+Y++ +Y P+LLIV+LSW+SFWIN DA+ ARV LGI +VL++ ++ + A
Sbjct: 259 IFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAA 318
Query: 307 SLPKVSYVKAIDIWMAVCLLFVFAALLEYAAV----NFVSRQHKEFLRLRRRQKRQNKEE 362
LPKVSYVKA+D+W+ CLLF FA+L+EYA V N R E R+ + ++ K
Sbjct: 319 ELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGG 378
Query: 363 DVTRESRFNFSGYGM--------------------------------------------- 377
+V +++ N +G +
Sbjct: 379 NVAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCY 438
Query: 378 GHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFY 437
G ++V +G N P P K AKRID +RA FP FL FN+ Y
Sbjct: 439 GKPIEVNNGLGKSQAKNNKKPPP------AKPVIPTAAKRIDLYARALFPFCFLFFNVIY 492
Query: 438 WITY 441
W Y
Sbjct: 493 WSIY 496
>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 2 precursor [Homo sapiens]
Length = 473
Score = 292 bits (747), Expect = 5e-79
Identities = 173/454 (38%), Positives = 250/454 (55%), Gaps = 49/454 (10%)
Query: 31 DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 90
+ RS P + +DKL+ GYD R+RP+F GPPV V NI I S ++E M
Sbjct: 24 EPRSVNDPGNMSFVKETVDKLL---KGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNM 80
Query: 91 DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
DY + ++ +Q W D RLAYS P + L LD + D +W PD +F N+K + H VT N+
Sbjct: 81 DYTLTMYFQQYWRDKRLAYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNR 139
Query: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLS-DGP 209
++R+ +G VLY +R+T T +C MDL+ +P+D Q CT+++ES+GYT +D+ F W D
Sbjct: 140 MIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKA 199
Query: 210 VQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIV 269
V E + LPQF + E + + + TG + + + F L+R +GY+++Q Y+PS+LI
Sbjct: 200 VTGVERIELPQFSIVEHRLVSRNVV-FATGAYPRLSLSFRLKRNIGYFILQTYMPSILIT 258
Query: 270 ILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF 329
ILSWVSFWIN DA+ ARVALGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FVF
Sbjct: 259 ILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVF 318
Query: 330 AALLEYAAVNFV------SRQHKEFLRLRRRQKRQNKEED-------------------- 363
ALLEYA VN++ RQ K + + + ++K E
Sbjct: 319 LALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEM 378
Query: 364 --------VTRESRFNFSGYGMGHCLQ--VKDGTAVKATPANPLPQPP----KDGDAIKK 409
TR S +F G+ + Q ++G + LP + +K
Sbjct: 379 NEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHG-RFLGDRSLPHKKTHLRRRSSQLKI 437
Query: 410 KFVD--RAKRIDTISRAAFPLAFLIFNIFYWITY 441
K D ID SR FP F +FN+ YW+ Y
Sbjct: 438 KIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYY 471
>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 1 precursor [Homo sapiens]
Length = 473
Score = 290 bits (743), Expect = 1e-78
Identities = 172/453 (37%), Positives = 250/453 (55%), Gaps = 49/453 (10%)
Query: 32 SRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMD 91
++S P + +DKL+ GYD R+RP+F GPPV V NI I S ++E MD
Sbjct: 25 AQSVNDPGNMSFVKETVDKLL---KGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMD 81
Query: 92 YRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKL 151
Y + ++ +Q W D RLAYS P + L LD + D +W PD +F N+K + H VT N++
Sbjct: 82 YTLTMYFQQYWRDKRLAYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 152 LRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLS-DGPV 210
+R+ +G VLY +R+T T +C MDL+ +P+D Q CT+++ES+GYT +D+ F W D V
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAV 200
Query: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
E + LPQF + E + + + TG + + + F L+R +GY+++Q Y+PS+LI I
Sbjct: 201 TGVERIELPQFSIVEHRLVSRNVV-FATGAYPRLSLSFRLKRNIGYFILQTYMPSILITI 259
Query: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
LSWVSFWIN DA+ ARVALGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FVF
Sbjct: 260 LSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFL 319
Query: 331 ALLEYAAVNFV------SRQHKEFLRLRRRQKRQNKEED--------------------- 363
ALLEYA VN++ RQ K + + + ++K E
Sbjct: 320 ALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMN 379
Query: 364 -------VTRESRFNFSGYGMGHCLQ--VKDGTAVKATPANPLPQPP----KDGDAIKKK 410
TR S +F G+ + Q ++G + LP + +K K
Sbjct: 380 EVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHG-RFLGDRSLPHKKTHLRRRSSQLKIK 438
Query: 411 FVD--RAKRIDTISRAAFPLAFLIFNIFYWITY 441
D ID SR FP F +FN+ YW+ Y
Sbjct: 439 IPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYY 471
>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
precursor [Homo sapiens]
Length = 474
Score = 290 bits (743), Expect = 1e-78
Identities = 167/453 (36%), Positives = 252/453 (55%), Gaps = 48/453 (10%)
Query: 32 SRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMD 91
+ S +PS + +D+L+ GYD R+RP+F GPPV+V I + S ++E MD
Sbjct: 25 AHSTNEPSNMSYVKETVDRLL---KGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMD 81
Query: 92 YRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKL 151
Y + ++ +Q W D RL+YS P + L LD + D +W PD +F N+K + H VT N++
Sbjct: 82 YTLTMYFQQSWKDKRLSYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140
Query: 152 LRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLS-DGPV 210
+R+ +G VLY +R+T T +C MDL+ +P+D Q CT+++ES+GYT +D+ F W +G V
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAV 200
Query: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
+ LPQF + + K + + + TG + + + F L+R +GY+++Q Y+PS LI I
Sbjct: 201 TGVNKIELPQFSIVDYKMVSKKVE-FTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITI 259
Query: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
LSWVSFWIN DA+ ARVALGITTVLTMTT S+ R +LPK+ YVKAIDI++ C +FVF
Sbjct: 260 LSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFL 319
Query: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYG--MGHCLQVKDGTA 388
ALLEYA VN++ + +Q + E++ ++ +G + L++++ T+
Sbjct: 320 ALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETS 379
Query: 389 ----------VKATP----------ANPLPQPPKDGDAIKKKFVDRAKR----------- 417
KAT PL G A+ + V R
Sbjct: 380 GSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRALDRHGVPSKGRIRRRASQLKVK 439
Query: 418 ---------IDTISRAAFPLAFLIFNIFYWITY 441
ID SR FP+ F +FN+ YW+ Y
Sbjct: 440 IPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYY 472
>gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta
precursor [Homo sapiens]
Length = 452
Score = 289 bits (739), Expect = 4e-78
Identities = 160/415 (38%), Positives = 236/415 (56%), Gaps = 24/415 (5%)
Query: 47 FLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSR 106
+L L G +GY RP GPPVNV + + S I+E M+Y + +FL Q W DSR
Sbjct: 40 WLPNLDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSR 99
Query: 107 LAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRL 166
L+Y+ + +++L LD +D +W PD F N K A FHDVT +NKL+R+ +G +LYSIR+
Sbjct: 100 LSYN-HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRI 158
Query: 167 TLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL-SDGPVQVAEGLTLPQFILKE 225
T T++C MDL +PMD Q C + LES+GY+ D+++ W S + + L L QF +
Sbjct: 159 TSTVACDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITS 218
Query: 226 EKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPA 285
+ + G+F + + FHL R G Y+IQ Y+PS+L+V +SWVSFWI+ A PA
Sbjct: 219 YRFTTELMNFKSAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPA 278
Query: 286 RVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQH 345
RV+LGITTVLTMTT +R+SLP+ S +KA+D++ +C +FVFAAL+EYA +F + +
Sbjct: 279 RVSLGITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHF-NADY 337
Query: 346 KEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPL-------- 397
++ + + + R E DV R + FS G ++ + P N +
Sbjct: 338 RKKQKAKVKVSRPRAEMDV-RNAIVLFSLSAAGVTQELAISRRQRRVPGNLMGSYRSVGV 396
Query: 398 --PQPPKDGDA---------IKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
+ K+G A + + +D A ID +RA FP AF N+ YW Y
Sbjct: 397 ETGETKKEGAARSGGQGGIRARLRPID-ADTIDIYARAVFPAAFAAVNVIYWAAY 450
>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 2 [Homo sapiens]
Length = 474
Score = 288 bits (737), Expect = 7e-78
Identities = 171/457 (37%), Positives = 258/457 (56%), Gaps = 55/457 (12%)
Query: 32 SRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMD 91
++S PS + +D+L+ GYD R+RP+F GPPV V NI I S ++E MD
Sbjct: 24 AQSVNDPSNMSLVKETVDRLL---KGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMD 80
Query: 92 YRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKL 151
Y + ++ +Q W D RL+Y+ P + L LD + D +W PD +F N+K + H VT N++
Sbjct: 81 YTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 139
Query: 152 LRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSD-GPV 210
+R+ +G VLY +R+T T +C MDL+ +P+D Q CT+++ES+GYT +D+ F W D V
Sbjct: 140 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAV 199
Query: 211 QVAEGLTLPQFILKEEKELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLI 268
+ LPQF + + K + TK ++TG + + + F L+R +GY+++Q Y+PS+LI
Sbjct: 200 TGVTKIELPQFSIVDYKLI---TKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILI 256
Query: 269 VILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFV 328
ILSWVSFWIN DA+ ARVALGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FV
Sbjct: 257 TILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFV 316
Query: 329 FAALLEYAAVNFV------SRQHK----------EFLRL--RRRQKRQN---KEEDVTRE 367
F ALLEYA VN++ RQ K E +RL + +N ++ E
Sbjct: 317 FMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKMDPHENILLSTLEIKNE 376
Query: 368 SRFNFSGYGMG---HCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKR------- 417
+ + G+G + D ++++ A LP+ +A+++ + R
Sbjct: 377 MATSEAVMGLGDPRSTMLAYDASSIQYRKAG-LPRHSFGRNALERHVAQKKSRLRRRASQ 435
Query: 418 -------------IDTISRAAFPLAFLIFNIFYWITY 441
ID SR FP+ F FNI YW+ Y
Sbjct: 436 LKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 472
>gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 1 [Homo sapiens]
Length = 512
Score = 281 bits (720), Expect = 7e-76
Identities = 147/329 (44%), Positives = 215/329 (65%), Gaps = 15/329 (4%)
Query: 32 SRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMD 91
++S PS + +D+L+ GYD R+RP+F GPPV V NI I S ++E MD
Sbjct: 24 AQSVNDPSNMSLVKETVDRLL---KGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMD 80
Query: 92 YRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKL 151
Y + ++ +Q W D RL+Y+ P + L LD + D +W PD +F N+K + H VT N++
Sbjct: 81 YTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 139
Query: 152 LRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSD-GPV 210
+R+ +G VLY +R+T T +C MDL+ +P+D Q CT+++ES+GYT +D+ F W D V
Sbjct: 140 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAV 199
Query: 211 QVAEGLTLPQFILKEEKELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLI 268
+ LPQF + + K + TK ++TG + + + F L+R +GY+++Q Y+PS+LI
Sbjct: 200 TGVTKIELPQFSIVDYKLI---TKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILI 256
Query: 269 VILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFV 328
ILSWVSFWIN DA+ ARVALGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FV
Sbjct: 257 TILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFV 316
Query: 329 FAALLEYAAVNFVSRQHKEFLRLRRRQKR 357
F ALLEYA VN++ F R +RQK+
Sbjct: 317 FMALLEYALVNYIF-----FGRGPQRQKK 340
Score = 31.6 bits (70), Expect = 1.5
Identities = 13/24 (54%), Positives = 15/24 (62%)
Query: 418 IDTISRAAFPLAFLIFNIFYWITY 441
ID SR FP+ F FNI YW+ Y
Sbjct: 487 IDRWSRIFFPVVFSFFNIVYWLYY 510
>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
[Homo sapiens]
Length = 453
Score = 276 bits (707), Expect = 2e-74
Identities = 158/422 (37%), Positives = 236/422 (55%), Gaps = 39/422 (9%)
Query: 45 SDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWND 104
S LD L+ GYD R+RP F G V +I++ SFG +++ M+Y +++F RQ W D
Sbjct: 33 SRILDNLL---EGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTD 89
Query: 105 SRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSI 164
RL + P + L L+ M+ IW PD FF N K + H++TT NKL RI +NG +LY++
Sbjct: 90 ERLKFGG-PTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTM 148
Query: 165 RLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILK 224
RLT+ CPM L NFPMD C ++ S+ Y +++I+ W GP+ E +L+
Sbjct: 149 RLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTW-KKGPLYSVEVPEESSSLLQ 207
Query: 225 EE---KELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMD 281
+ + + T NTG++ + V FHL+R+MGY++IQ+Y P ++ VILS VSFWIN +
Sbjct: 208 YDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267
Query: 282 AAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFV 341
+ PAR GITTVLTMTT S +R SLPKVSY A+D ++AVC FVF+AL+E+AAVN+
Sbjct: 268 SVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF 327
Query: 342 -------SRQHKEF-----LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGT-- 387
+++ +F + + + + E + +S+++ L + +
Sbjct: 328 TNLQTQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSSEA 387
Query: 388 --------AVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWI 439
+++TP P P P G K ID SR FP+AF FN+ YW+
Sbjct: 388 NKVLTRAPILQSTPVTPPPLSPAFGGTSK---------IDQYSRILFPVAFAGFNLVYWV 438
Query: 440 TY 441
Y
Sbjct: 439 VY 440
>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
sapiens]
Length = 451
Score = 276 bits (705), Expect = 4e-74
Identities = 154/401 (38%), Positives = 240/401 (59%), Gaps = 13/401 (3%)
Query: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
LD+L+ GYD R+RP V NI++ SFG +++T M+Y +++F RQ+W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
+ P + L L+ M IW PD FF N K + H++T NKLLRI +G +LY++RLT
Sbjct: 103 KFKG-PMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 161
Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVA-EGLTLPQFILK 224
+ CPM L++FPMD +C ++ S+ YT +++ + W + VQVA +G L Q+ L
Sbjct: 162 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 221
Query: 225 EEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAP 284
+ +G T +TG++T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ P
Sbjct: 222 GQS-IGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 280
Query: 285 ARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQ 344
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ +++
Sbjct: 281 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
Query: 345 HKEF-LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQP--- 400
+ + K++ K + + + + + L KD + + P+P
Sbjct: 341 GWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLS-KDPVLSTISKSATTPEPNKK 399
Query: 401 PKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
P++ A KK + +ID +SR FP+ F FN+ YW TY
Sbjct: 400 PENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
[Homo sapiens]
Length = 451
Score = 276 bits (705), Expect = 4e-74
Identities = 154/401 (38%), Positives = 240/401 (59%), Gaps = 13/401 (3%)
Query: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
LD+L+ GYD R+RP V NI++ SFG +++T M+Y +++F RQ+W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
+ P + L L+ M IW PD FF N K + H++T NKLLRI +G +LY++RLT
Sbjct: 103 KFKG-PMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 161
Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVA-EGLTLPQFILK 224
+ CPM L++FPMD +C ++ S+ YT +++ + W + VQVA +G L Q+ L
Sbjct: 162 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 221
Query: 225 EEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAP 284
+ +G T +TG++T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ P
Sbjct: 222 GQS-IGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 280
Query: 285 ARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQ 344
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ +++
Sbjct: 281 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
Query: 345 HKEF-LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQP--- 400
+ + K++ K + + + + + L KD + + P+P
Sbjct: 341 GWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLS-KDPVLSTISKSATTPEPNKK 399
Query: 401 PKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
P++ A KK + +ID +SR FP+ F FN+ YW TY
Sbjct: 400 PENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
>gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2
precursor [Homo sapiens]
Length = 490
Score = 276 bits (705), Expect = 4e-74
Identities = 149/405 (36%), Positives = 233/405 (57%), Gaps = 17/405 (4%)
Query: 54 RTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYP 113
R +D +RP F GP + V ++ + S SI+E MD+ + ++LR W D RLA+S
Sbjct: 85 RVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSAS 144
Query: 114 DDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCP 173
+ S+ D ++ IW PD+FF + K + HD TTDN +LR+ +G VLYS+R+T+T C
Sbjct: 145 NKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCN 204
Query: 174 MDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLS-DGPVQVAEGLTLPQFILKEEKELGYC 232
MD +FP+D QTC+++LES+ YT DL+ W + D ++ E ++L QF++++
Sbjct: 205 MDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRL 264
Query: 233 TKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGIT 292
+ +TG + + + F L R + ++L+Q Y P+ L+V+LSWVSFWI+ A PARV+LGIT
Sbjct: 265 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 324
Query: 293 TVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR-QHKEFLRL 351
TVLTMTT +G AS+P+VSYVKA+DI++ V +FVF ++LEYAAVN+++ Q ++ +L
Sbjct: 325 TVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKL 384
Query: 352 RRR---------QKRQNKEEDVTRESRFNFSGYGMGHCL---QVKDGTAVKATPANPLPQ 399
R + K + + + +GY H L + +D V +
Sbjct: 385 REKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANA 444
Query: 400 PPKDG---DAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
K G + ID SR FP +++ FN+ YW +
Sbjct: 445 ARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
>gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1 [Homo
sapiens]
Length = 479
Score = 275 bits (704), Expect = 5e-74
Identities = 151/416 (36%), Positives = 240/416 (57%), Gaps = 16/416 (3%)
Query: 36 KQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVN 95
+ P T SP ++L+ R +D +RP F GP + V ++ + S SI+E MD+ +
Sbjct: 63 RSPDITKSPLTKSEQLL-RIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMT 121
Query: 96 IFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIS 155
++LR W D RL++ + S+ D ++ IW PD+FF + K + HD TTDN +LR+
Sbjct: 122 LYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQ 181
Query: 156 KNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEW-LSDGPVQVAE 214
+GKVLYS+R+T+T C MD FP+D QTC++++ES+ YT +DL+ W + ++ E
Sbjct: 182 PDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDE 241
Query: 215 GLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWV 274
++L QF+++E + +TG + + + F L R + ++L+Q Y P+ L+V+LSWV
Sbjct: 242 RISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWV 301
Query: 275 SFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLE 334
SFWI+ A PARV LGITTVLTM+T +G AS+P+VSY+KA+DI++ V +FVF ++LE
Sbjct: 302 SFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLE 361
Query: 335 YAAVNFVSR-QHKEFLRLRRR--------QKRQNKEEDVTRESRFNFSGYGMGHCLQVKD 385
YAAVN+++ Q ++ +LR + R + + N M + D
Sbjct: 362 YAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPD 421
Query: 386 GTAVKATPANPLPQPPKDGDAIKKKFVDR---AKRIDTISRAAFPLAFLIFNIFYW 438
V+ T A+ P + + +V ID SR FP A+++FN+ YW
Sbjct: 422 RMMVQLTLASERSSPQRKSQ--RSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYW 475
>gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 275 bits (703), Expect = 6e-74
Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%)
Query: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
+ P L L+ M IW PD FF N K + H++T NKLLRI+++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
+ CPM L++FPMD C ++ S+ YT ++++EW + V VAE G L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
+ + G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
+ + ++ K +D + ++ + + G T K+ P
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
Query: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
P+ KK + +ID +SR AFPL F IFN+ YW TY
Sbjct: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 275 bits (703), Expect = 6e-74
Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%)
Query: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
+ P L L+ M IW PD FF N K + H++T NKLLRI+++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
+ CPM L++FPMD C ++ S+ YT ++++EW + V VAE G L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
+ + G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
+ + ++ K +D + ++ + + G T K+ P
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
Query: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
P+ KK + +ID +SR AFPL F IFN+ YW TY
Sbjct: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 275 bits (703), Expect = 6e-74
Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%)
Query: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
+ P L L+ M IW PD FF N K + H++T NKLLRI+++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
+ CPM L++FPMD C ++ S+ YT ++++EW + V VAE G L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
+ + G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
+ + ++ K +D + ++ + + G T K+ P
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
Query: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
P+ KK + +ID +SR AFPL F IFN+ YW TY
Sbjct: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 275 bits (703), Expect = 6e-74
Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%)
Query: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
+ P L L+ M IW PD FF N K + H++T NKLLRI+++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
+ CPM L++FPMD C ++ S+ YT ++++EW + V VAE G L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
+ + G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
+ + ++ K +D + ++ + + G T K+ P
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
Query: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
P+ KK + +ID +SR AFPL F IFN+ YW TY
Sbjct: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 275 bits (703), Expect = 6e-74
Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%)
Query: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
+ P L L+ M IW PD FF N K + H++T NKLLRI+++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
+ CPM L++FPMD C ++ S+ YT ++++EW + V VAE G L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
+ + G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
+ + ++ K +D + ++ + + G T K+ P
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
Query: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
P+ KK + +ID +SR AFPL F IFN+ YW TY
Sbjct: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 275 bits (703), Expect = 6e-74
Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%)
Query: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
+ P L L+ M IW PD FF N K + H++T NKLLRI+++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
+ CPM L++FPMD C ++ S+ YT ++++EW + V VAE G L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
+ + G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
+ + ++ K +D + ++ + + G T K+ P
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
Query: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
P+ KK + +ID +SR AFPL F IFN+ YW TY
Sbjct: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 275 bits (703), Expect = 6e-74
Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%)
Query: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
LD+L+ GYD R+RP V +IF+ SFG +++ M+Y +++F RQ W D RL
Sbjct: 46 LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102
Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
+ P L L+ M IW PD FF N K + H++T NKLLRI+++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161
Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
+ CPM L++FPMD C ++ S+ YT ++++EW + V VAE G L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221
Query: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
+ + G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279
Query: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
PAR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339
Query: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
+ + ++ K +D + ++ + + G T K+ P
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399
Query: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
P+ KK + +ID +SR AFPL F IFN+ YW TY
Sbjct: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442
>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
precursor [Homo sapiens]
Length = 462
Score = 274 bits (701), Expect = 1e-73
Identities = 152/398 (38%), Positives = 236/398 (59%), Gaps = 9/398 (2%)
Query: 51 LMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYS 110
L G GYD R+RP V +I++ SFG +++T M+Y +++F RQ W D RL +
Sbjct: 53 LDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFK 112
Query: 111 EYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTL 170
P L L+ + IW PD FF N K + H++TT NKLLR+ +G +LY++RLT++
Sbjct: 113 G-PMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISA 171
Query: 171 SCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVAE-GLTLPQFILKEEK 227
CPM L++FPMD C ++ S+ Y +++++ W S V VAE G L Q+ L +
Sbjct: 172 ECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
Query: 228 ELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARV 287
+G +TG++T + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ PAR
Sbjct: 232 -VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPART 290
Query: 288 ALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKE 347
G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ +++
Sbjct: 291 VFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWA 350
Query: 348 F--LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQV-KDGT-AVKATPANPLPQPPKD 403
+ + K + K E + +S F+ M H + K+ T A + + +P ++
Sbjct: 351 WDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEE 410
Query: 404 GDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
+ KK + +ID +SR FP+ F FN+ YW TY
Sbjct: 411 KTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY 448
>gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo
sapiens]
Length = 440
Score = 274 bits (701), Expect = 1e-73
Identities = 145/398 (36%), Positives = 226/398 (56%), Gaps = 16/398 (4%)
Query: 55 TSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPD 114
T+GY+ +RPNF G PV + + I S SI+E+ MDY I+LRQ+W D RL + +
Sbjct: 45 TAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEG--N 102
Query: 115 DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPM 174
S LD +++ +W PD + K + H+VT N+L+R+ NG VLY++R+T T++C M
Sbjct: 103 KSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNM 162
Query: 175 DLKNFPMDVQTCTMQLESFGYTMNDLIFEWL-SDGPVQVAEGLTLPQFILKEEKELGYCT 233
DL +PMD QTC +QLES+GY ND+ F WL + V+ E L L Q+ ++ L
Sbjct: 163 DLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTL-VTR 221
Query: 234 KHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITT 293
TG +T + ++F L R + Y++++ Y+PS +V+LSWVSFWI++D+ PAR +G+TT
Sbjct: 222 SQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTT 281
Query: 294 VLTMTTQSSGSRASLPKVS-YVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLR 352
VL+MTT GSR SLP + ++KAID+++ +C FVF ALLEYA ++ S Q +
Sbjct: 282 VLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQ--QMAAKD 339
Query: 353 RRQKRQNKEEDVTR---------ESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKD 403
R ++ +E +T + + +F+ + +K + K
Sbjct: 340 RGTTKEVEEVSITNIINSSISSFKRKISFASIEISSDNVDYSDLTMKTSDKFKFVFREKM 399
Query: 404 GDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
G + + +D S+ FPL F++ N+FYW Y
Sbjct: 400 GRIVDYFTIQNPSNVDHYSKLLFPLIFMLANVFYWAYY 437
>gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor
[Homo sapiens]
Length = 492
Score = 270 bits (690), Expect = 2e-72
Identities = 153/413 (37%), Positives = 235/413 (56%), Gaps = 24/413 (5%)
Query: 48 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
LD+L+ GYD R+RP V +I++ SFG +++T M+Y +++F RQ W+D RL
Sbjct: 71 LDRLL---DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127
Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
+ + P L L+ + IW PD FF N K + H++TT NKLLR+ NG +LY++RLT
Sbjct: 128 KF-DGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186
Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVAE-GLTLPQFILK 224
+ CPM L++FPMDV C ++ S+ YT ++++ W + V+VA+ G L Q+ L
Sbjct: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246
Query: 225 EEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAP 284
+G +TG++ + FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ P
Sbjct: 247 GHV-VGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 305
Query: 285 ARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR- 343
AR G+TTVLTMTT S +R SLPKV+Y A+D ++AVC FVF+AL+E+A VN+ ++
Sbjct: 306 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 365
Query: 344 ----QHKEFLRLRRRQKRQNKEEDVTRESRFNFSG--YGMG-----HCLQVKDGTAVKAT 392
+ K+ +K+ + FN G Y + + G A A+
Sbjct: 366 SWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSAS 425
Query: 393 PANPLPQPPK----DGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
+ PK + K + ++D ISR FP+ F IFN+ YW TY
Sbjct: 426 STPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATY 478
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,126,365
Number of Sequences: 37866
Number of extensions: 741711
Number of successful extensions: 2600
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2393
Number of HSP's gapped (non-prelim): 98
length of query: 452
length of database: 18,247,518
effective HSP length: 106
effective length of query: 346
effective length of database: 14,233,722
effective search space: 4924867812
effective search space used: 4924867812
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.