Guide to the Human Genome
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Search of human proteins with 169646728

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
         (452 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]       921   0.0  
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]       919   0.0  
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]         919   0.0  
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]       726   0.0  
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]       721   0.0  
gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo...   702   0.0  
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo...   698   0.0  
gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens]       657   0.0  
gi|4504023 glycine receptor, beta [Homo sapiens]                      374   e-103
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is...   292   5e-79
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso...   290   1e-78
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p...   290   1e-78
gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta pre...   289   4e-78
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso...   288   7e-78
gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2 is...   281   7e-76
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs...   276   2e-74
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s...   276   4e-74
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs...   276   4e-74
gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2 prec...   276   4e-74
gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1 [Hom...   275   5e-74
gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ...   275   6e-74
gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ...   275   6e-74
gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ...   275   6e-74
gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ...   275   6e-74
gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ...   275   6e-74
gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ...   275   6e-74
gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 p...   275   6e-74
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr...   274   1e-73
gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo s...   274   1e-73
gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor...   270   2e-72

>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
          Length = 452

 Score =  921 bits (2380), Expect = 0.0
 Identities = 452/452 (100%), Positives = 452/452 (100%)

Query: 1   MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA 60
           MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA
Sbjct: 1   MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA 60

Query: 61  RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD 120
           RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD
Sbjct: 61  RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD 120

Query: 121 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP 180
           PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP
Sbjct: 121 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP 180

Query: 181 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK 240
           MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK
Sbjct: 181 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK 240

Query: 241 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 300
           FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ
Sbjct: 241 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 300

Query: 301 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK 360
           SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK
Sbjct: 301 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK 360

Query: 361 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT 420
           EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT
Sbjct: 361 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT 420

Query: 421 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 452
           ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK
Sbjct: 421 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 452


>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
          Length = 452

 Score =  919 bits (2375), Expect = 0.0
 Identities = 450/452 (99%), Positives = 451/452 (99%)

Query: 1   MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA 60
           MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA
Sbjct: 1   MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA 60

Query: 61  RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD 120
           RIRPNFKGPPVNVTCNIFINSFGS+ ETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD
Sbjct: 61  RIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD 120

Query: 121 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP 180
           PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP
Sbjct: 121 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP 180

Query: 181 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK 240
           MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK
Sbjct: 181 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK 240

Query: 241 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 300
           FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ
Sbjct: 241 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 300

Query: 301 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK 360
           SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK
Sbjct: 301 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK 360

Query: 361 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT 420
           EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT
Sbjct: 361 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT 420

Query: 421 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 452
           ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK
Sbjct: 421 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 452


>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
          Length = 452

 Score =  919 bits (2375), Expect = 0.0
 Identities = 450/452 (99%), Positives = 451/452 (99%)

Query: 1   MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA 60
           MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA
Sbjct: 1   MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA 60

Query: 61  RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD 120
           RIRPNFKGPPVNVTCNIFINSFGS+ ETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD
Sbjct: 61  RIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD 120

Query: 121 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP 180
           PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP
Sbjct: 121 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP 180

Query: 181 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK 240
           MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK
Sbjct: 181 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK 240

Query: 241 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 300
           FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ
Sbjct: 241 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 300

Query: 301 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK 360
           SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK
Sbjct: 301 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK 360

Query: 361 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT 420
           EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT
Sbjct: 361 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT 420

Query: 421 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 452
           ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK
Sbjct: 421 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 452


>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
          Length = 449

 Score =  726 bits (1875), Expect = 0.0
 Identities = 357/422 (84%), Positives = 385/422 (91%), Gaps = 4/422 (0%)

Query: 31  DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 90
           ++ S +  S  +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM
Sbjct: 30  ETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 89

Query: 91  DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
           DYRVNIFLRQ+WND RLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH+VTTDNK
Sbjct: 90  DYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNK 149

Query: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
           LLRI KNG VLYSIRLTLTLSCPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW  + PV
Sbjct: 150 LLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPV 209

Query: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
           QVAEGLTLPQF+LKEEK+L YCTKHYNTGKFTCIEV+FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 210 QVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVI 269

Query: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
           LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 270 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 329

Query: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVK 390
           ALLEYAAVNFVSRQHKE LR RR  KR+NK+++V RESRF+F+ YGMG CLQ KDG   K
Sbjct: 330 ALLEYAAVNFVSRQHKELLRFRR--KRKNKDDEV-RESRFSFTAYGMGPCLQAKDGMTPK 386

Query: 391 ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVH 450
             P +P+   PK  D ++K F+DRAK+IDTISRA FPLAFLIFNIFYW+ YKI+RHED+H
Sbjct: 387 G-PNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIH 445

Query: 451 KK 452
           ++
Sbjct: 446 QQ 447


>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
          Length = 464

 Score =  721 bits (1860), Expect = 0.0
 Identities = 354/434 (81%), Positives = 383/434 (88%), Gaps = 13/434 (2%)

Query: 31  DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 90
           ++ S +  S  +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM
Sbjct: 30  ETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 89

Query: 91  DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
           DYRVNIFLRQ+WND RLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFH+VTTDNK
Sbjct: 90  DYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNK 149

Query: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
           LLRI KNG VLYSIRLTLTLSCPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW  + PV
Sbjct: 150 LLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPV 209

Query: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
           QVAEGLTLPQF+LKEEK+L YCTKHYNTGKFTCIEV+FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 210 QVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVI 269

Query: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
           LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 270 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 329

Query: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKE------------EDVTRESRFNFSGYGMG 378
           ALLEYAAVNFVSRQHKE LR RR++K + +             +D  RESRF+F+ YGMG
Sbjct: 330 ALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMG 389

Query: 379 HCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYW 438
            CLQ KDG   K  P +P+   PK  D ++K F+DRAK+IDTISRA FPLAFLIFNIFYW
Sbjct: 390 PCLQAKDGMTPKG-PNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYW 448

Query: 439 ITYKIIRHEDVHKK 452
           + YKI+RHED+H++
Sbjct: 449 VIYKILRHEDIHQQ 462


>gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 449

 Score =  702 bits (1811), Expect = 0.0
 Identities = 343/427 (80%), Positives = 376/427 (88%), Gaps = 7/427 (1%)

Query: 31  DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 90
           ++ + +   + +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+CNIFINSFGSIAETTM
Sbjct: 25  EAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTM 84

Query: 91  DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
           DYRVNIFLRQQWND RLAY+EYPDDSLDLDPSMLDSIWKPDLFFANEKGA+FH++TTDNK
Sbjct: 85  DYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNK 144

Query: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
           LLRIS+NG VLYSIR+TLTL+CPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW   G V
Sbjct: 145 LLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAV 204

Query: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
           QVA+GLTLPQFILKEEK+L YCTKHYNTGKFTCIE +FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 205 QVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVI 264

Query: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
           LSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 265 LSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 324

Query: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMG-HCLQVKDGTAV 389
           ALLEYAAVNFVSRQHKE LR RR  KR++ +ED   E RFNFS YGMG  CLQ KDG +V
Sbjct: 325 ALLEYAAVNFVSRQHKELLRFRR--KRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISV 382

Query: 390 K----ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIR 445
           K    +   NP P P K  + ++K F+ RAK+ID ISR  FP+AFLIFN+FYWI YKI+R
Sbjct: 383 KGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVR 442

Query: 446 HEDVHKK 452
            EDVH +
Sbjct: 443 REDVHNQ 449


>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 457

 Score =  698 bits (1802), Expect = 0.0
 Identities = 341/433 (78%), Positives = 375/433 (86%), Gaps = 11/433 (2%)

Query: 31  DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 90
           ++ + +   + +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNV+CNIFINSFGSIAETTM
Sbjct: 25  EAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTM 84

Query: 91  DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
           DYRVNIFLRQQWND RLAY+EYPDDSLDLDPSMLDSIWKPDLFFANEKGA+FH++TTDNK
Sbjct: 85  DYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNK 144

Query: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPV 210
           LLRIS+NG VLYSIR+TLTL+CPMDLKNFPMDVQTC MQLESFGYTMNDLIFEW   G V
Sbjct: 145 LLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAV 204

Query: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
           QVA+GLTLPQFILKEEK+L YCTKHYNTGKFTCIE +FHLERQMGYYLIQMYIPSLLIVI
Sbjct: 205 QVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVI 264

Query: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
           LSW+SFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF+
Sbjct: 265 LSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFS 324

Query: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNK------EEDVTRESRFNFSGYGMG-HCLQV 383
           ALLEYAAVNFVSRQHKE LR RR+++          +ED   E RFNFS YGMG  CLQ 
Sbjct: 325 ALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQA 384

Query: 384 KDGTAVK----ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWI 439
           KDG +VK    +   NP P P K  + ++K F+ RAK+ID ISR  FP+AFLIFN+FYWI
Sbjct: 385 KDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWI 444

Query: 440 TYKIIRHEDVHKK 452
            YKI+R EDVH +
Sbjct: 445 IYKIVRREDVHNQ 457


>gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens]
          Length = 417

 Score =  657 bits (1694), Expect = 0.0
 Identities = 324/396 (81%), Positives = 353/396 (89%), Gaps = 7/396 (1%)

Query: 23  RTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSF 82
           R A  K+ + +SG + SQ +SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSF
Sbjct: 24  RVALAKE-EVKSGTKGSQPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSF 82

Query: 83  GSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANF 142
            SI +TTMDYRVN+FLRQQWND RL+Y EYPDDSLDLDPSMLDSIWKPDLFFANEKGANF
Sbjct: 83  SSITKTTMDYRVNVFLRQQWNDPRLSYREYPDDSLDLDPSMLDSIWKPDLFFANEKGANF 142

Query: 143 HDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIF 202
           H+VTTDNKLLRI KNG VLYSIRLTL LSC MDLKNFPMD+QTCTMQLESFGYTM DL+F
Sbjct: 143 HEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNFPMDIQTCTMQLESFGYTMKDLVF 202

Query: 203 EWLSDGP-VQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQM 261
           EWL D P VQVAEGLTLPQFIL++EK+LG CTKHYNTGKFTCIEVKFHLERQMGYYLIQM
Sbjct: 203 EWLEDAPAVQVAEGLTLPQFILRDEKDLGCCTKHYNTGKFTCIEVKFHLERQMGYYLIQM 262

Query: 262 YIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWM 321
           YIPSLLIVILSWVSFWINMDAAPARV LGITTVLTMTTQSSGSRASLPKVSYVKAIDIWM
Sbjct: 263 YIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWM 322

Query: 322 AVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCL 381
           AVCLLFVFAALLEYAA+NFVSRQHKEF+RLRRRQ+RQ  EED+ +ESRF F GYG+GHCL
Sbjct: 323 AVCLLFVFAALLEYAAINFVSRQHKEFIRLRRRQRRQRLEEDIIQESRFYFRGYGLGHCL 382

Query: 382 QVKDGTAVKATPANPLPQPP----KDGDAIKKKFVD 413
           Q +DG  ++ +     PQPP    ++G+  +K +VD
Sbjct: 383 QARDGGPMEGSGIYS-PQPPAPLLREGETTRKLYVD 417


>gi|4504023 glycine receptor, beta [Homo sapiens]
          Length = 497

 Score =  374 bits (959), Expect = e-103
 Identities = 220/484 (45%), Positives = 285/484 (58%), Gaps = 74/484 (15%)

Query: 25  AFCKDHDSRSGKQ-------PSQTLS------PSDFLDKLMGRTS-GYDARIRPNFKGPP 70
           A+ K+  S+ GK        PSQ  +      P++    ++ R    YD RIRPNFKG P
Sbjct: 20  AYSKEKSSKKGKGKKKQYLCPSQQSAEDLARVPANSTSNILNRLLVSYDPRIRPNFKGIP 79

Query: 71  VNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAY-SEYP-DDSLDLDPSMLDSIW 128
           V+V  NIFINSFGSI ETTMDYRVNIFLRQ+WND RL   S++   D+L +DP+M   +W
Sbjct: 80  VDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLW 139

Query: 129 KPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTM 188
           KPDLFFANEK ANFHDVT +N LL I ++G VL S+RL++TLSCP+DL  FPMD Q C M
Sbjct: 140 KPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKM 199

Query: 189 QLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQF-ILKEEKELGYCTKHY-NTGKFTCIEV 246
           QLESFGYT +DL F W S  PVQ+ E + LPQF I KE+ E G CTK+Y  TG +TC+EV
Sbjct: 200 QLESFGYTTDDLRFIWQSGDPVQL-EKIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEV 258

Query: 247 KFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRA 306
            F L RQ+G+Y++ +Y P+LLIV+LSW+SFWIN DA+ ARV LGI +VL++ ++ +   A
Sbjct: 259 IFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAA 318

Query: 307 SLPKVSYVKAIDIWMAVCLLFVFAALLEYAAV----NFVSRQHKEFLRLRRRQKRQNKEE 362
            LPKVSYVKA+D+W+  CLLF FA+L+EYA V    N   R   E  R+ + ++   K  
Sbjct: 319 ELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGG 378

Query: 363 DVTRESRFNFSGYGM--------------------------------------------- 377
           +V +++  N +G  +                                             
Sbjct: 379 NVAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCY 438

Query: 378 GHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFY 437
           G  ++V +G        N  P P       K      AKRID  +RA FP  FL FN+ Y
Sbjct: 439 GKPIEVNNGLGKSQAKNNKKPPP------AKPVIPTAAKRIDLYARALFPFCFLFFNVIY 492

Query: 438 WITY 441
           W  Y
Sbjct: 493 WSIY 496


>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
           isoform 2 precursor [Homo sapiens]
          Length = 473

 Score =  292 bits (747), Expect = 5e-79
 Identities = 173/454 (38%), Positives = 250/454 (55%), Gaps = 49/454 (10%)

Query: 31  DSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM 90
           + RS   P       + +DKL+    GYD R+RP+F GPPV V  NI I S   ++E  M
Sbjct: 24  EPRSVNDPGNMSFVKETVDKLL---KGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNM 80

Query: 91  DYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNK 150
           DY + ++ +Q W D RLAYS  P + L LD  + D +W PD +F N+K +  H VT  N+
Sbjct: 81  DYTLTMYFQQYWRDKRLAYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNR 139

Query: 151 LLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLS-DGP 209
           ++R+  +G VLY +R+T T +C MDL+ +P+D Q CT+++ES+GYT +D+ F W   D  
Sbjct: 140 MIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKA 199

Query: 210 VQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIV 269
           V   E + LPQF + E + +      + TG +  + + F L+R +GY+++Q Y+PS+LI 
Sbjct: 200 VTGVERIELPQFSIVEHRLVSRNVV-FATGAYPRLSLSFRLKRNIGYFILQTYMPSILIT 258

Query: 270 ILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVF 329
           ILSWVSFWIN DA+ ARVALGITTVLTMTT ++  R +LPK+ YVKAID+++  C +FVF
Sbjct: 259 ILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVF 318

Query: 330 AALLEYAAVNFV------SRQHKEFLRLRRRQKRQNKEED-------------------- 363
            ALLEYA VN++       RQ K   +  + +  ++K E                     
Sbjct: 319 LALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEM 378

Query: 364 --------VTRESRFNFSGYGMGHCLQ--VKDGTAVKATPANPLPQPP----KDGDAIKK 409
                    TR S  +F   G+ +  Q   ++G   +      LP       +    +K 
Sbjct: 379 NEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHG-RFLGDRSLPHKKTHLRRRSSQLKI 437

Query: 410 KFVD--RAKRIDTISRAAFPLAFLIFNIFYWITY 441
           K  D      ID  SR  FP  F +FN+ YW+ Y
Sbjct: 438 KIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYY 471


>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
           isoform 1 precursor [Homo sapiens]
          Length = 473

 Score =  290 bits (743), Expect = 1e-78
 Identities = 172/453 (37%), Positives = 250/453 (55%), Gaps = 49/453 (10%)

Query: 32  SRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMD 91
           ++S   P       + +DKL+    GYD R+RP+F GPPV V  NI I S   ++E  MD
Sbjct: 25  AQSVNDPGNMSFVKETVDKLL---KGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMD 81

Query: 92  YRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKL 151
           Y + ++ +Q W D RLAYS  P + L LD  + D +W PD +F N+K +  H VT  N++
Sbjct: 82  YTLTMYFQQYWRDKRLAYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140

Query: 152 LRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLS-DGPV 210
           +R+  +G VLY +R+T T +C MDL+ +P+D Q CT+++ES+GYT +D+ F W   D  V
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAV 200

Query: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
              E + LPQF + E + +      + TG +  + + F L+R +GY+++Q Y+PS+LI I
Sbjct: 201 TGVERIELPQFSIVEHRLVSRNVV-FATGAYPRLSLSFRLKRNIGYFILQTYMPSILITI 259

Query: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
           LSWVSFWIN DA+ ARVALGITTVLTMTT ++  R +LPK+ YVKAID+++  C +FVF 
Sbjct: 260 LSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFL 319

Query: 331 ALLEYAAVNFV------SRQHKEFLRLRRRQKRQNKEED--------------------- 363
           ALLEYA VN++       RQ K   +  + +  ++K E                      
Sbjct: 320 ALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMN 379

Query: 364 -------VTRESRFNFSGYGMGHCLQ--VKDGTAVKATPANPLPQPP----KDGDAIKKK 410
                   TR S  +F   G+ +  Q   ++G   +      LP       +    +K K
Sbjct: 380 EVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHG-RFLGDRSLPHKKTHLRRRSSQLKIK 438

Query: 411 FVD--RAKRIDTISRAAFPLAFLIFNIFYWITY 441
             D      ID  SR  FP  F +FN+ YW+ Y
Sbjct: 439 IPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYY 471


>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
           precursor [Homo sapiens]
          Length = 474

 Score =  290 bits (743), Expect = 1e-78
 Identities = 167/453 (36%), Positives = 252/453 (55%), Gaps = 48/453 (10%)

Query: 32  SRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMD 91
           + S  +PS      + +D+L+    GYD R+RP+F GPPV+V   I + S   ++E  MD
Sbjct: 25  AHSTNEPSNMSYVKETVDRLL---KGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMD 81

Query: 92  YRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKL 151
           Y + ++ +Q W D RL+YS  P + L LD  + D +W PD +F N+K +  H VT  N++
Sbjct: 82  YTLTMYFQQSWKDKRLSYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 140

Query: 152 LRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLS-DGPV 210
           +R+  +G VLY +R+T T +C MDL+ +P+D Q CT+++ES+GYT +D+ F W   +G V
Sbjct: 141 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAV 200

Query: 211 QVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVI 270
                + LPQF + + K +    + + TG +  + + F L+R +GY+++Q Y+PS LI I
Sbjct: 201 TGVNKIELPQFSIVDYKMVSKKVE-FTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITI 259

Query: 271 LSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFA 330
           LSWVSFWIN DA+ ARVALGITTVLTMTT S+  R +LPK+ YVKAIDI++  C +FVF 
Sbjct: 260 LSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFL 319

Query: 331 ALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYG--MGHCLQVKDGTA 388
           ALLEYA VN++        +   +Q +   E++    ++     +G  +   L++++ T+
Sbjct: 320 ALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETS 379

Query: 389 ----------VKATP----------ANPLPQPPKDGDAIKKKFVDRAKR----------- 417
                      KAT             PL      G A+ +  V    R           
Sbjct: 380 GSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRALDRHGVPSKGRIRRRASQLKVK 439

Query: 418 ---------IDTISRAAFPLAFLIFNIFYWITY 441
                    ID  SR  FP+ F +FN+ YW+ Y
Sbjct: 440 IPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYY 472


>gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta
           precursor [Homo sapiens]
          Length = 452

 Score =  289 bits (739), Expect = 4e-78
 Identities = 160/415 (38%), Positives = 236/415 (56%), Gaps = 24/415 (5%)

Query: 47  FLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSR 106
           +L  L G  +GY    RP   GPPVNV   + + S   I+E  M+Y + +FL Q W DSR
Sbjct: 40  WLPNLDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSR 99

Query: 107 LAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRL 166
           L+Y+ + +++L LD   +D +W PD F  N K A FHDVT +NKL+R+  +G +LYSIR+
Sbjct: 100 LSYN-HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRI 158

Query: 167 TLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL-SDGPVQVAEGLTLPQFILKE 225
           T T++C MDL  +PMD Q C + LES+GY+  D+++ W  S   +   + L L QF +  
Sbjct: 159 TSTVACDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITS 218

Query: 226 EKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPA 285
            +         + G+F  + + FHL R  G Y+IQ Y+PS+L+V +SWVSFWI+  A PA
Sbjct: 219 YRFTTELMNFKSAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPA 278

Query: 286 RVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQH 345
           RV+LGITTVLTMTT    +R+SLP+ S +KA+D++  +C +FVFAAL+EYA  +F +  +
Sbjct: 279 RVSLGITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHF-NADY 337

Query: 346 KEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPL-------- 397
           ++  + + +  R   E DV R +   FS    G   ++      +  P N +        
Sbjct: 338 RKKQKAKVKVSRPRAEMDV-RNAIVLFSLSAAGVTQELAISRRQRRVPGNLMGSYRSVGV 396

Query: 398 --PQPPKDGDA---------IKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
              +  K+G A          + + +D A  ID  +RA FP AF   N+ YW  Y
Sbjct: 397 ETGETKKEGAARSGGQGGIRARLRPID-ADTIDIYARAVFPAAFAAVNVIYWAAY 450


>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
           isoform 2 [Homo sapiens]
          Length = 474

 Score =  288 bits (737), Expect = 7e-78
 Identities = 171/457 (37%), Positives = 258/457 (56%), Gaps = 55/457 (12%)

Query: 32  SRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMD 91
           ++S   PS      + +D+L+    GYD R+RP+F GPPV V  NI I S   ++E  MD
Sbjct: 24  AQSVNDPSNMSLVKETVDRLL---KGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMD 80

Query: 92  YRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKL 151
           Y + ++ +Q W D RL+Y+  P + L LD  + D +W PD +F N+K +  H VT  N++
Sbjct: 81  YTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 139

Query: 152 LRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSD-GPV 210
           +R+  +G VLY +R+T T +C MDL+ +P+D Q CT+++ES+GYT +D+ F W  D   V
Sbjct: 140 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAV 199

Query: 211 QVAEGLTLPQFILKEEKELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLI 268
                + LPQF + + K +   TK   ++TG +  + + F L+R +GY+++Q Y+PS+LI
Sbjct: 200 TGVTKIELPQFSIVDYKLI---TKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILI 256

Query: 269 VILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFV 328
            ILSWVSFWIN DA+ ARVALGITTVLTMTT ++  R +LPK+ YVKAID+++  C +FV
Sbjct: 257 TILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFV 316

Query: 329 FAALLEYAAVNFV------SRQHK----------EFLRL--RRRQKRQN---KEEDVTRE 367
           F ALLEYA VN++       RQ K          E +RL   +    +N      ++  E
Sbjct: 317 FMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKMDPHENILLSTLEIKNE 376

Query: 368 SRFNFSGYGMG---HCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKR------- 417
              + +  G+G     +   D ++++   A  LP+     +A+++    +  R       
Sbjct: 377 MATSEAVMGLGDPRSTMLAYDASSIQYRKAG-LPRHSFGRNALERHVAQKKSRLRRRASQ 435

Query: 418 -------------IDTISRAAFPLAFLIFNIFYWITY 441
                        ID  SR  FP+ F  FNI YW+ Y
Sbjct: 436 LKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYY 472


>gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2
           isoform 1 [Homo sapiens]
          Length = 512

 Score =  281 bits (720), Expect = 7e-76
 Identities = 147/329 (44%), Positives = 215/329 (65%), Gaps = 15/329 (4%)

Query: 32  SRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMD 91
           ++S   PS      + +D+L+    GYD R+RP+F GPPV V  NI I S   ++E  MD
Sbjct: 24  AQSVNDPSNMSLVKETVDRLL---KGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMD 80

Query: 92  YRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKL 151
           Y + ++ +Q W D RL+Y+  P + L LD  + D +W PD +F N+K +  H VT  N++
Sbjct: 81  YTLTMYFQQAWRDKRLSYNVIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRM 139

Query: 152 LRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSD-GPV 210
           +R+  +G VLY +R+T T +C MDL+ +P+D Q CT+++ES+GYT +D+ F W  D   V
Sbjct: 140 IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAV 199

Query: 211 QVAEGLTLPQFILKEEKELGYCTKH--YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLI 268
                + LPQF + + K +   TK   ++TG +  + + F L+R +GY+++Q Y+PS+LI
Sbjct: 200 TGVTKIELPQFSIVDYKLI---TKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILI 256

Query: 269 VILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFV 328
            ILSWVSFWIN DA+ ARVALGITTVLTMTT ++  R +LPK+ YVKAID+++  C +FV
Sbjct: 257 TILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFV 316

Query: 329 FAALLEYAAVNFVSRQHKEFLRLRRRQKR 357
           F ALLEYA VN++      F R  +RQK+
Sbjct: 317 FMALLEYALVNYIF-----FGRGPQRQKK 340



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 13/24 (54%), Positives = 15/24 (62%)

Query: 418 IDTISRAAFPLAFLIFNIFYWITY 441
           ID  SR  FP+ F  FNI YW+ Y
Sbjct: 487 IDRWSRIFFPVVFSFFNIVYWLYY 510


>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
           [Homo sapiens]
          Length = 453

 Score =  276 bits (707), Expect = 2e-74
 Identities = 158/422 (37%), Positives = 236/422 (55%), Gaps = 39/422 (9%)

Query: 45  SDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWND 104
           S  LD L+    GYD R+RP F G    V  +I++ SFG +++  M+Y +++F RQ W D
Sbjct: 33  SRILDNLL---EGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTD 89

Query: 105 SRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSI 164
            RL +   P + L L+  M+  IW PD FF N K +  H++TT NKL RI +NG +LY++
Sbjct: 90  ERLKFGG-PTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTM 148

Query: 165 RLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILK 224
           RLT+   CPM L NFPMD   C ++  S+ Y  +++I+ W   GP+   E       +L+
Sbjct: 149 RLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTW-KKGPLYSVEVPEESSSLLQ 207

Query: 225 EE---KELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMD 281
            +   + +   T   NTG++  + V FHL+R+MGY++IQ+Y P ++ VILS VSFWIN +
Sbjct: 208 YDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKE 267

Query: 282 AAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFV 341
           + PAR   GITTVLTMTT S  +R SLPKVSY  A+D ++AVC  FVF+AL+E+AAVN+ 
Sbjct: 268 SVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF 327

Query: 342 -------SRQHKEF-----LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGT-- 387
                  +++  +F     + + +  +    E  +  +S+++         L +   +  
Sbjct: 328 TNLQTQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSSEA 387

Query: 388 --------AVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWI 439
                    +++TP  P P  P  G   K         ID  SR  FP+AF  FN+ YW+
Sbjct: 388 NKVLTRAPILQSTPVTPPPLSPAFGGTSK---------IDQYSRILFPVAFAGFNLVYWV 438

Query: 440 TY 441
            Y
Sbjct: 439 VY 440


>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
           sapiens]
          Length = 451

 Score =  276 bits (705), Expect = 4e-74
 Identities = 154/401 (38%), Positives = 240/401 (59%), Gaps = 13/401 (3%)

Query: 48  LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
           LD+L+    GYD R+RP        V  NI++ SFG +++T M+Y +++F RQ+W D RL
Sbjct: 46  LDRLL---DGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102

Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
            +   P + L L+  M   IW PD FF N K +  H++T  NKLLRI  +G +LY++RLT
Sbjct: 103 KFKG-PMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 161

Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVA-EGLTLPQFILK 224
           +   CPM L++FPMD  +C ++  S+ YT +++ + W   +   VQVA +G  L Q+ L 
Sbjct: 162 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 221

Query: 225 EEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAP 284
            +  +G  T   +TG++T +   FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ P
Sbjct: 222 GQS-IGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 280

Query: 285 ARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQ 344
           AR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVF+AL+E+A VN+ +++
Sbjct: 281 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340

Query: 345 HKEF-LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQP--- 400
              +  +     K++ K   + + + +  +       L  KD      + +   P+P   
Sbjct: 341 GWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLS-KDPVLSTISKSATTPEPNKK 399

Query: 401 PKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
           P++  A  KK  +   +ID +SR  FP+ F  FN+ YW TY
Sbjct: 400 PENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 440


>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
           [Homo sapiens]
          Length = 451

 Score =  276 bits (705), Expect = 4e-74
 Identities = 154/401 (38%), Positives = 240/401 (59%), Gaps = 13/401 (3%)

Query: 48  LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
           LD+L+    GYD R+RP        V  NI++ SFG +++T M+Y +++F RQ+W D RL
Sbjct: 46  LDRLL---DGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102

Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
            +   P + L L+  M   IW PD FF N K +  H++T  NKLLRI  +G +LY++RLT
Sbjct: 103 KFKG-PMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLT 161

Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVA-EGLTLPQFILK 224
           +   CPM L++FPMD  +C ++  S+ YT +++ + W   +   VQVA +G  L Q+ L 
Sbjct: 162 VQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLL 221

Query: 225 EEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAP 284
            +  +G  T   +TG++T +   FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ P
Sbjct: 222 GQS-IGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 280

Query: 285 ARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQ 344
           AR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVF+AL+E+A VN+ +++
Sbjct: 281 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340

Query: 345 HKEF-LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQP--- 400
              +  +     K++ K   + + + +  +       L  KD      + +   P+P   
Sbjct: 341 GWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLS-KDPVLSTISKSATTPEPNKK 399

Query: 401 PKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
           P++  A  KK  +   +ID +SR  FP+ F  FN+ YW TY
Sbjct: 400 PENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 440


>gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2
           precursor [Homo sapiens]
          Length = 490

 Score =  276 bits (705), Expect = 4e-74
 Identities = 149/405 (36%), Positives = 233/405 (57%), Gaps = 17/405 (4%)

Query: 54  RTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYP 113
           R   +D  +RP F GP + V  ++ + S  SI+E  MD+ + ++LR  W D RLA+S   
Sbjct: 85  RVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSAS 144

Query: 114 DDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCP 173
           + S+  D  ++  IW PD+FF + K +  HD TTDN +LR+  +G VLYS+R+T+T  C 
Sbjct: 145 NKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCN 204

Query: 174 MDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLS-DGPVQVAEGLTLPQFILKEEKELGYC 232
           MD  +FP+D QTC+++LES+ YT  DL+  W + D  ++  E ++L QF++++       
Sbjct: 205 MDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRL 264

Query: 233 TKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGIT 292
             + +TG +  + + F L R + ++L+Q Y P+ L+V+LSWVSFWI+  A PARV+LGIT
Sbjct: 265 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 324

Query: 293 TVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR-QHKEFLRL 351
           TVLTMTT  +G  AS+P+VSYVKA+DI++ V  +FVF ++LEYAAVN+++  Q ++  +L
Sbjct: 325 TVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKL 384

Query: 352 RRR---------QKRQNKEEDVTRESRFNFSGYGMGHCL---QVKDGTAVKATPANPLPQ 399
           R +          K    +   +     + +GY   H L   + +D   V    +     
Sbjct: 385 REKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANA 444

Query: 400 PPKDG---DAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
             K G        +       ID  SR  FP +++ FN+ YW  +
Sbjct: 445 ARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489


>gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1 [Homo
           sapiens]
          Length = 479

 Score =  275 bits (704), Expect = 5e-74
 Identities = 151/416 (36%), Positives = 240/416 (57%), Gaps = 16/416 (3%)

Query: 36  KQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVN 95
           + P  T SP    ++L+ R   +D  +RP F GP + V  ++ + S  SI+E  MD+ + 
Sbjct: 63  RSPDITKSPLTKSEQLL-RIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMT 121

Query: 96  IFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIS 155
           ++LR  W D RL++    + S+  D  ++  IW PD+FF + K +  HD TTDN +LR+ 
Sbjct: 122 LYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQ 181

Query: 156 KNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEW-LSDGPVQVAE 214
            +GKVLYS+R+T+T  C MD   FP+D QTC++++ES+ YT +DL+  W   +  ++  E
Sbjct: 182 PDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDE 241

Query: 215 GLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWV 274
            ++L QF+++E         + +TG +  + + F L R + ++L+Q Y P+ L+V+LSWV
Sbjct: 242 RISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWV 301

Query: 275 SFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLE 334
           SFWI+  A PARV LGITTVLTM+T  +G  AS+P+VSY+KA+DI++ V  +FVF ++LE
Sbjct: 302 SFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLE 361

Query: 335 YAAVNFVSR-QHKEFLRLRRR--------QKRQNKEEDVTRESRFNFSGYGMGHCLQVKD 385
           YAAVN+++  Q ++  +LR +          R    +    +   N     M    +  D
Sbjct: 362 YAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPD 421

Query: 386 GTAVKATPANPLPQPPKDGDAIKKKFVDR---AKRIDTISRAAFPLAFLIFNIFYW 438
              V+ T A+    P +     +  +V        ID  SR  FP A+++FN+ YW
Sbjct: 422 RMMVQLTLASERSSPQRKSQ--RSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYW 475


>gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  275 bits (703), Expect = 6e-74
 Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%)

Query: 48  LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
           LD+L+    GYD R+RP        V  +IF+ SFG +++  M+Y +++F RQ W D RL
Sbjct: 46  LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102

Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
            +   P   L L+  M   IW PD FF N K +  H++T  NKLLRI+++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161

Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
           +   CPM L++FPMD   C ++  S+ YT  ++++EW  +    V VAE G  L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221

Query: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
            +  + G      +TG++  +   FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ 
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279

Query: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
           PAR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVF+AL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339

Query: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
           +   +       ++  K +D   +    ++     +   +  G     T  K+    P  
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399

Query: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
             P+      KK  +   +ID +SR AFPL F IFN+ YW TY
Sbjct: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442


>gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  275 bits (703), Expect = 6e-74
 Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%)

Query: 48  LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
           LD+L+    GYD R+RP        V  +IF+ SFG +++  M+Y +++F RQ W D RL
Sbjct: 46  LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102

Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
            +   P   L L+  M   IW PD FF N K +  H++T  NKLLRI+++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161

Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
           +   CPM L++FPMD   C ++  S+ YT  ++++EW  +    V VAE G  L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221

Query: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
            +  + G      +TG++  +   FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ 
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279

Query: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
           PAR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVF+AL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339

Query: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
           +   +       ++  K +D   +    ++     +   +  G     T  K+    P  
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399

Query: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
             P+      KK  +   +ID +SR AFPL F IFN+ YW TY
Sbjct: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442


>gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  275 bits (703), Expect = 6e-74
 Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%)

Query: 48  LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
           LD+L+    GYD R+RP        V  +IF+ SFG +++  M+Y +++F RQ W D RL
Sbjct: 46  LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102

Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
            +   P   L L+  M   IW PD FF N K +  H++T  NKLLRI+++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161

Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
           +   CPM L++FPMD   C ++  S+ YT  ++++EW  +    V VAE G  L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221

Query: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
            +  + G      +TG++  +   FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ 
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279

Query: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
           PAR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVF+AL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339

Query: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
           +   +       ++  K +D   +    ++     +   +  G     T  K+    P  
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399

Query: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
             P+      KK  +   +ID +SR AFPL F IFN+ YW TY
Sbjct: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442


>gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  275 bits (703), Expect = 6e-74
 Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%)

Query: 48  LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
           LD+L+    GYD R+RP        V  +IF+ SFG +++  M+Y +++F RQ W D RL
Sbjct: 46  LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102

Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
            +   P   L L+  M   IW PD FF N K +  H++T  NKLLRI+++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161

Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
           +   CPM L++FPMD   C ++  S+ YT  ++++EW  +    V VAE G  L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221

Query: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
            +  + G      +TG++  +   FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ 
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279

Query: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
           PAR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVF+AL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339

Query: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
           +   +       ++  K +D   +    ++     +   +  G     T  K+    P  
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399

Query: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
             P+      KK  +   +ID +SR AFPL F IFN+ YW TY
Sbjct: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442


>gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  275 bits (703), Expect = 6e-74
 Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%)

Query: 48  LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
           LD+L+    GYD R+RP        V  +IF+ SFG +++  M+Y +++F RQ W D RL
Sbjct: 46  LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102

Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
            +   P   L L+  M   IW PD FF N K +  H++T  NKLLRI+++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161

Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
           +   CPM L++FPMD   C ++  S+ YT  ++++EW  +    V VAE G  L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221

Query: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
            +  + G      +TG++  +   FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ 
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279

Query: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
           PAR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVF+AL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339

Query: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
           +   +       ++  K +D   +    ++     +   +  G     T  K+    P  
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399

Query: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
             P+      KK  +   +ID +SR AFPL F IFN+ YW TY
Sbjct: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442


>gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  275 bits (703), Expect = 6e-74
 Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%)

Query: 48  LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
           LD+L+    GYD R+RP        V  +IF+ SFG +++  M+Y +++F RQ W D RL
Sbjct: 46  LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102

Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
            +   P   L L+  M   IW PD FF N K +  H++T  NKLLRI+++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161

Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
           +   CPM L++FPMD   C ++  S+ YT  ++++EW  +    V VAE G  L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221

Query: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
            +  + G      +TG++  +   FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ 
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279

Query: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
           PAR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVF+AL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339

Query: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
           +   +       ++  K +D   +    ++     +   +  G     T  K+    P  
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399

Query: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
             P+      KK  +   +ID +SR AFPL F IFN+ YW TY
Sbjct: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442


>gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1
           precursor [Homo sapiens]
          Length = 456

 Score =  275 bits (703), Expect = 6e-74
 Identities = 153/403 (37%), Positives = 234/403 (58%), Gaps = 15/403 (3%)

Query: 48  LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
           LD+L+    GYD R+RP        V  +IF+ SFG +++  M+Y +++F RQ W D RL
Sbjct: 46  LDRLL---DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERL 102

Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
            +   P   L L+  M   IW PD FF N K +  H++T  NKLLRI+++G +LY++RLT
Sbjct: 103 KFKG-PMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT 161

Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGP--VQVAE-GLTLPQF-IL 223
           +   CPM L++FPMD   C ++  S+ YT  ++++EW  +    V VAE G  L Q+ +L
Sbjct: 162 VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLL 221

Query: 224 KEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 283
            +  + G      +TG++  +   FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ 
Sbjct: 222 GQTVDSGIVQS--STGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 279

Query: 284 PARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR 343
           PAR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVF+AL+E+A VN+ ++
Sbjct: 280 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTK 339

Query: 344 QHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDG-----TAVKATPANPLP 398
           +   +       ++  K +D   +    ++     +   +  G     T  K+    P  
Sbjct: 340 RGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKE 399

Query: 399 QPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
             P+      KK  +   +ID +SR AFPL F IFN+ YW TY
Sbjct: 400 VKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATY 442


>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
           precursor [Homo sapiens]
          Length = 462

 Score =  274 bits (701), Expect = 1e-73
 Identities = 152/398 (38%), Positives = 236/398 (59%), Gaps = 9/398 (2%)

Query: 51  LMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYS 110
           L G   GYD R+RP        V  +I++ SFG +++T M+Y +++F RQ W D RL + 
Sbjct: 53  LDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFK 112

Query: 111 EYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTL 170
             P   L L+  +   IW PD FF N K +  H++TT NKLLR+  +G +LY++RLT++ 
Sbjct: 113 G-PMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISA 171

Query: 171 SCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVAE-GLTLPQFILKEEK 227
            CPM L++FPMD   C ++  S+ Y  +++++ W   S   V VAE G  L Q+ L  + 
Sbjct: 172 ECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231

Query: 228 ELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARV 287
            +G      +TG++T +   FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ PAR 
Sbjct: 232 -VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPART 290

Query: 288 ALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKE 347
             G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVF+AL+E+A VN+ +++   
Sbjct: 291 VFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWA 350

Query: 348 F--LRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQV-KDGT-AVKATPANPLPQPPKD 403
           +   +     K + K E +  +S   F+   M H   + K+ T A  +   +   +P ++
Sbjct: 351 WDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEE 410

Query: 404 GDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
             +  KK  +   +ID +SR  FP+ F  FN+ YW TY
Sbjct: 411 KTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY 448


>gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo
           sapiens]
          Length = 440

 Score =  274 bits (701), Expect = 1e-73
 Identities = 145/398 (36%), Positives = 226/398 (56%), Gaps = 16/398 (4%)

Query: 55  TSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPD 114
           T+GY+  +RPNF G PV +   + I S  SI+E+ MDY   I+LRQ+W D RL +    +
Sbjct: 45  TAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEG--N 102

Query: 115 DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPM 174
            S  LD  +++ +W PD +    K +  H+VT  N+L+R+  NG VLY++R+T T++C M
Sbjct: 103 KSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNM 162

Query: 175 DLKNFPMDVQTCTMQLESFGYTMNDLIFEWL-SDGPVQVAEGLTLPQFILKEEKELGYCT 233
           DL  +PMD QTC +QLES+GY  ND+ F WL  +  V+  E L L Q+ ++    L    
Sbjct: 163 DLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTL-VTR 221

Query: 234 KHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITT 293
               TG +T + ++F L R + Y++++ Y+PS  +V+LSWVSFWI++D+ PAR  +G+TT
Sbjct: 222 SQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTT 281

Query: 294 VLTMTTQSSGSRASLPKVS-YVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLR 352
           VL+MTT   GSR SLP  + ++KAID+++ +C  FVF ALLEYA  ++ S Q  +     
Sbjct: 282 VLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQ--QMAAKD 339

Query: 353 RRQKRQNKEEDVTR---------ESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKD 403
           R   ++ +E  +T          + + +F+   +           +K +         K 
Sbjct: 340 RGTTKEVEEVSITNIINSSISSFKRKISFASIEISSDNVDYSDLTMKTSDKFKFVFREKM 399

Query: 404 GDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
           G  +    +     +D  S+  FPL F++ N+FYW  Y
Sbjct: 400 GRIVDYFTIQNPSNVDHYSKLLFPLIFMLANVFYWAYY 437


>gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor
           [Homo sapiens]
          Length = 492

 Score =  270 bits (690), Expect = 2e-72
 Identities = 153/413 (37%), Positives = 235/413 (56%), Gaps = 24/413 (5%)

Query: 48  LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRL 107
           LD+L+    GYD R+RP        V  +I++ SFG +++T M+Y +++F RQ W+D RL
Sbjct: 71  LDRLL---DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERL 127

Query: 108 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLT 167
            + + P   L L+  +   IW PD FF N K +  H++TT NKLLR+  NG +LY++RLT
Sbjct: 128 KF-DGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLT 186

Query: 168 LTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWL--SDGPVQVAE-GLTLPQFILK 224
           +   CPM L++FPMDV  C ++  S+ YT  ++++ W    +  V+VA+ G  L Q+ L 
Sbjct: 187 IHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLL 246

Query: 225 EEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAP 284
               +G      +TG++  +   FHL+R++GY++IQ Y+P ++ VILS VSFW+N ++ P
Sbjct: 247 GHV-VGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 305

Query: 285 ARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR- 343
           AR   G+TTVLTMTT S  +R SLPKV+Y  A+D ++AVC  FVF+AL+E+A VN+ ++ 
Sbjct: 306 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 365

Query: 344 ----QHKEFLRLRRRQKRQNKEEDVTRESRFNFSG--YGMG-----HCLQVKDGTAVKAT 392
               + K+       +K+          + FN  G  Y +          +  G A  A+
Sbjct: 366 SWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSAS 425

Query: 393 PANPLPQPPK----DGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
               +   PK         + K  +   ++D ISR  FP+ F IFN+ YW TY
Sbjct: 426 STPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATY 478


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.137    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,126,365
Number of Sequences: 37866
Number of extensions: 741711
Number of successful extensions: 2600
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2393
Number of HSP's gapped (non-prelim): 98
length of query: 452
length of database: 18,247,518
effective HSP length: 106
effective length of query: 346
effective length of database: 14,233,722
effective search space: 4924867812
effective search space used: 4924867812
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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