Guide to the Human Genome
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Search of human proteins with 169234665

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169234665 tumor protein p63 isoform 6 [Homo sapiens]
         (393 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169234665 tumor protein p63 isoform 6 [Homo sapiens]               806   0.0  
gi|169234659 tumor protein p63 isoform 3 [Homo sapiens]               779   0.0  
gi|169234663 tumor protein p63 isoform 5 [Homo sapiens]               726   0.0  
gi|169234661 tumor protein p63 isoform 4 [Homo sapiens]               726   0.0  
gi|169234657 tumor protein p63 isoform 2 [Homo sapiens]               699   0.0  
gi|31543818 tumor protein p63 isoform 1 [Homo sapiens]                699   0.0  
gi|187829017 tumor protein p73 isoform c [Homo sapiens]               482   e-136
gi|187828902 tumor protein p73 isoform b [Homo sapiens]               482   e-136
gi|4885645 tumor protein p73 isoform a [Homo sapiens]                 482   e-136
gi|187829052 tumor protein p73 isoform d [Homo sapiens]               481   e-136
gi|187830777 tumor protein p53 isoform a [Homo sapiens]               273   3e-73
gi|120407068 tumor protein p53 isoform a [Homo sapiens]               273   3e-73
gi|187830855 tumor protein p53 isoform b [Homo sapiens]               253   3e-67
gi|187830823 tumor protein p53 isoform c [Homo sapiens]               253   3e-67
gi|187830894 tumor protein p53 isoform d [Homo sapiens]               236   2e-62
gi|187830909 tumor protein p53 isoform f [Homo sapiens]               216   2e-56
gi|187830901 tumor protein p53 isoform e [Homo sapiens]               216   2e-56
gi|239582749 sterile alpha motif domain containing 4 isoform 2 [...    35   0.15 
gi|239582747 sterile alpha motif domain containing 4 isoform 1 [...    35   0.15 
gi|206597502 NESH protein isoform 2 [Homo sapiens]                     34   0.20 
gi|7705981 NESH protein isoform 1 [Homo sapiens]                       34   0.20 
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]            34   0.26 
gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens]            34   0.26 
gi|119943102 CREB binding protein isoform b [Homo sapiens]             33   0.34 
gi|119943104 CREB binding protein isoform a [Homo sapiens]             33   0.34 
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             33   0.45 
gi|148746195 trichohyalin [Homo sapiens]                               33   0.58 
gi|58530840 desmoplakin isoform I [Homo sapiens]                       32   0.76 
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    32   1.3  
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...    32   1.3  

>gi|169234665 tumor protein p63 isoform 6 [Homo sapiens]
          Length = 393

 Score =  806 bits (2082), Expect = 0.0
 Identities = 393/393 (100%), Positives = 393/393 (100%)

Query: 1   MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS 60
           MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS
Sbjct: 1   MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS 60

Query: 61  TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK 120
           TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK
Sbjct: 61  TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK 120

Query: 121 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ 180
           VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ
Sbjct: 121 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ 180

Query: 181 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV 240
           YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV
Sbjct: 181 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV 240

Query: 241 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR 300
           LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR
Sbjct: 241 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR 300

Query: 301 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKHLLSA 360
           SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKHLLSA
Sbjct: 301 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKHLLSA 360

Query: 361 CFRNELVEPRRETPKQSDVFFRHSKPPNRSVYP 393
           CFRNELVEPRRETPKQSDVFFRHSKPPNRSVYP
Sbjct: 361 CFRNELVEPRRETPKQSDVFFRHSKPPNRSVYP 393


>gi|169234659 tumor protein p63 isoform 3 [Homo sapiens]
          Length = 487

 Score =  779 bits (2011), Expect = 0.0
 Identities = 379/379 (100%), Positives = 379/379 (100%)

Query: 15  PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN 74
           PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN
Sbjct: 109 PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN 168

Query: 75  TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM 134
           TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM
Sbjct: 169 TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM 228

Query: 135 PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV 194
           PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV
Sbjct: 229 PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV 288

Query: 195 PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP 254
           PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP
Sbjct: 289 PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP 348

Query: 255 GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR 314
           GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR
Sbjct: 349 GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR 408

Query: 315 ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKHLLSACFRNELVEPRRETP 374
           ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKHLLSACFRNELVEPRRETP
Sbjct: 409 ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKHLLSACFRNELVEPRRETP 468

Query: 375 KQSDVFFRHSKPPNRSVYP 393
           KQSDVFFRHSKPPNRSVYP
Sbjct: 469 KQSDVFFRHSKPPNRSVYP 487


>gi|169234663 tumor protein p63 isoform 5 [Homo sapiens]
          Length = 461

 Score =  726 bits (1875), Expect = 0.0
 Identities = 355/355 (100%), Positives = 355/355 (100%)

Query: 1   MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS 60
           MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS
Sbjct: 1   MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS 60

Query: 61  TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK 120
           TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK
Sbjct: 61  TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK 120

Query: 121 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ 180
           VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ
Sbjct: 121 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ 180

Query: 181 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV 240
           YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV
Sbjct: 181 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV 240

Query: 241 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR 300
           LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR
Sbjct: 241 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR 300

Query: 301 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK 355
           SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK
Sbjct: 301 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK 355


>gi|169234661 tumor protein p63 isoform 4 [Homo sapiens]
          Length = 586

 Score =  726 bits (1875), Expect = 0.0
 Identities = 355/355 (100%), Positives = 355/355 (100%)

Query: 1   MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS 60
           MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS
Sbjct: 1   MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS 60

Query: 61  TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK 120
           TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK
Sbjct: 61  TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK 120

Query: 121 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ 180
           VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ
Sbjct: 121 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ 180

Query: 181 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV 240
           YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV
Sbjct: 181 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV 240

Query: 241 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR 300
           LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR
Sbjct: 241 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR 300

Query: 301 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK 355
           SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK
Sbjct: 301 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK 355


>gi|169234657 tumor protein p63 isoform 2 [Homo sapiens]
          Length = 555

 Score =  699 bits (1804), Expect = 0.0
 Identities = 341/341 (100%), Positives = 341/341 (100%)

Query: 15  PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN 74
           PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN
Sbjct: 109 PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN 168

Query: 75  TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM 134
           TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM
Sbjct: 169 TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM 228

Query: 135 PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV 194
           PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV
Sbjct: 229 PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV 288

Query: 195 PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP 254
           PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP
Sbjct: 289 PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP 348

Query: 255 GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR 314
           GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR
Sbjct: 349 GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR 408

Query: 315 ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK 355
           ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK
Sbjct: 409 ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK 449


>gi|31543818 tumor protein p63 isoform 1 [Homo sapiens]
          Length = 680

 Score =  699 bits (1804), Expect = 0.0
 Identities = 341/341 (100%), Positives = 341/341 (100%)

Query: 15  PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN 74
           PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN
Sbjct: 109 PQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSN 168

Query: 75  TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM 134
           TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM
Sbjct: 169 TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAM 228

Query: 135 PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV 194
           PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV
Sbjct: 229 PVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLV 288

Query: 195 PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP 254
           PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP
Sbjct: 289 PYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACP 348

Query: 255 GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR 314
           GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR
Sbjct: 349 GRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGR 408

Query: 315 ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK 355
           ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK
Sbjct: 409 ETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQK 449


>gi|187829017 tumor protein p73 isoform c [Homo sapiens]
          Length = 450

 Score =  482 bits (1241), Expect = e-136
 Identities = 238/337 (70%), Positives = 275/337 (81%), Gaps = 7/337 (2%)

Query: 22  LLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPH 81
           LL+S   Q+ + ++S SPY  +HA  SV   SPYAQPSSTFD +SP+P IPSNTDYPGPH
Sbjct: 18  LLSSTMDQMSSRAASASPYTPEHAA-SVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPH 76

Query: 82  SFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAE 141
            F+V+FQQSSTAKSATWTYS  LKKLYCQIAKTCPIQIKV TPPP G  IRAMPVYKKAE
Sbjct: 77  HFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAE 136

Query: 142 HVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQV 201
           HVT+VVKRCPNHEL R+FNEGQ AP SHLIRVEGN+ +QYV+DP+TGRQSV+VPYEPPQV
Sbjct: 137 HVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQV 196

Query: 202 GTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKAD 261
           GTEFTT+LYNFMCNSSCVGGMNRRPILII+TLE RDGQVLGRR FE RICACPGRDRKAD
Sbjct: 197 GTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKAD 256

Query: 262 EDSIRKQQV--SDSTKNGDGTKRPFRQNTHGIQM--TSIKKRRSPDDELLYLPVRGRETY 317
           ED  R+QQ     S KNG  +KR F+Q+   +      +KKRR  D++  YL VRGRE +
Sbjct: 257 EDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENF 316

Query: 318 EMLLKIKESLELMQYLPQHTIETYRQQQQ--QQHQHL 352
           E+L+K+KESLELM+ +PQ  +++YRQQQQ  Q+  HL
Sbjct: 317 EILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHL 353


>gi|187828902 tumor protein p73 isoform b [Homo sapiens]
          Length = 587

 Score =  482 bits (1241), Expect = e-136
 Identities = 238/337 (70%), Positives = 275/337 (81%), Gaps = 7/337 (2%)

Query: 22  LLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPH 81
           LL+S   Q+ + ++S SPY  +HA  SV   SPYAQPSSTFD +SP+P IPSNTDYPGPH
Sbjct: 18  LLSSTMDQMSSRAASASPYTPEHAA-SVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPH 76

Query: 82  SFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAE 141
            F+V+FQQSSTAKSATWTYS  LKKLYCQIAKTCPIQIKV TPPP G  IRAMPVYKKAE
Sbjct: 77  HFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAE 136

Query: 142 HVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQV 201
           HVT+VVKRCPNHEL R+FNEGQ AP SHLIRVEGN+ +QYV+DP+TGRQSV+VPYEPPQV
Sbjct: 137 HVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQV 196

Query: 202 GTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKAD 261
           GTEFTT+LYNFMCNSSCVGGMNRRPILII+TLE RDGQVLGRR FE RICACPGRDRKAD
Sbjct: 197 GTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKAD 256

Query: 262 EDSIRKQQV--SDSTKNGDGTKRPFRQNTHGIQM--TSIKKRRSPDDELLYLPVRGRETY 317
           ED  R+QQ     S KNG  +KR F+Q+   +      +KKRR  D++  YL VRGRE +
Sbjct: 257 EDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENF 316

Query: 318 EMLLKIKESLELMQYLPQHTIETYRQQQQ--QQHQHL 352
           E+L+K+KESLELM+ +PQ  +++YRQQQQ  Q+  HL
Sbjct: 317 EILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHL 353


>gi|4885645 tumor protein p73 isoform a [Homo sapiens]
          Length = 636

 Score =  482 bits (1241), Expect = e-136
 Identities = 238/337 (70%), Positives = 275/337 (81%), Gaps = 7/337 (2%)

Query: 22  LLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPH 81
           LL+S   Q+ + ++S SPY  +HA  SV   SPYAQPSSTFD +SP+P IPSNTDYPGPH
Sbjct: 67  LLSSTMDQMSSRAASASPYTPEHAA-SVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPH 125

Query: 82  SFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAE 141
            F+V+FQQSSTAKSATWTYS  LKKLYCQIAKTCPIQIKV TPPP G  IRAMPVYKKAE
Sbjct: 126 HFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAE 185

Query: 142 HVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQV 201
           HVT+VVKRCPNHEL R+FNEGQ AP SHLIRVEGN+ +QYV+DP+TGRQSV+VPYEPPQV
Sbjct: 186 HVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQV 245

Query: 202 GTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKAD 261
           GTEFTT+LYNFMCNSSCVGGMNRRPILII+TLE RDGQVLGRR FE RICACPGRDRKAD
Sbjct: 246 GTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKAD 305

Query: 262 EDSIRKQQV--SDSTKNGDGTKRPFRQNTHGIQM--TSIKKRRSPDDELLYLPVRGRETY 317
           ED  R+QQ     S KNG  +KR F+Q+   +      +KKRR  D++  YL VRGRE +
Sbjct: 306 EDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENF 365

Query: 318 EMLLKIKESLELMQYLPQHTIETYRQQQQ--QQHQHL 352
           E+L+K+KESLELM+ +PQ  +++YRQQQQ  Q+  HL
Sbjct: 366 EILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHL 402


>gi|187829052 tumor protein p73 isoform d [Homo sapiens]
          Length = 426

 Score =  481 bits (1238), Expect = e-136
 Identities = 235/329 (71%), Positives = 271/329 (82%), Gaps = 5/329 (1%)

Query: 22  LLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPH 81
           LL+S   Q+ + ++S SPY  +HA  SV   SPYAQPSSTFD +SP+P IPSNTDYPGPH
Sbjct: 18  LLSSTMDQMSSRAASASPYTPEHAA-SVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPH 76

Query: 82  SFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAE 141
            F+V+FQQSSTAKSATWTYS  LKKLYCQIAKTCPIQIKV TPPP G  IRAMPVYKKAE
Sbjct: 77  HFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAE 136

Query: 142 HVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQV 201
           HVT+VVKRCPNHEL R+FNEGQ AP SHLIRVEGN+ +QYV+DP+TGRQSV+VPYEPPQV
Sbjct: 137 HVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQV 196

Query: 202 GTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKAD 261
           GTEFTT+LYNFMCNSSCVGGMNRRPILII+TLE RDGQVLGRR FE RICACPGRDRKAD
Sbjct: 197 GTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKAD 256

Query: 262 EDSIRKQQV--SDSTKNGDGTKRPFRQNTHGIQM--TSIKKRRSPDDELLYLPVRGRETY 317
           ED  R+QQ     S KNG  +KR F+Q+   +      +KKRR  D++  YL VRGRE +
Sbjct: 257 EDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENF 316

Query: 318 EMLLKIKESLELMQYLPQHTIETYRQQQQ 346
           E+L+K+KESLELM+ +PQ  +++YRQQQQ
Sbjct: 317 EILMKLKESLELMELVPQPLVDSYRQQQQ 345


>gi|187830777 tumor protein p53 isoform a [Homo sapiens]
          Length = 393

 Score =  273 bits (697), Expect = 3e-73
 Identities = 138/283 (48%), Positives = 188/283 (66%), Gaps = 10/283 (3%)

Query: 51  APSPYAQPSSTFDALSPS----PAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKK 106
           AP+P A P+    A +PS     ++PS   Y G + F + F  S TAKS T TYS  L K
Sbjct: 74  APAP-AAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNK 132

Query: 107 LYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAP 166
           ++CQ+AKTCP+Q+ V + PP G  +RAM +YK+++H+TEVV+RCP+HE  R  +   +AP
Sbjct: 133 MFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE--RCSDSDGLAP 190

Query: 167 PSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRP 226
           P HLIRVEGN   +Y++D  T R SV+VPYEPP+VG++ TT+ YN+MCNSSC+GGMNRRP
Sbjct: 191 PQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRP 250

Query: 227 ILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQ 286
           IL I+TLE   G +LGR  FE R+CACPGRDR+ +E+++RK+           TKR    
Sbjct: 251 ILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPN 310

Query: 287 NTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLEL 329
           NT     +   K++  D E   L +RGRE +EM  ++ E+LEL
Sbjct: 311 NT---SSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALEL 350


>gi|120407068 tumor protein p53 isoform a [Homo sapiens]
          Length = 393

 Score =  273 bits (697), Expect = 3e-73
 Identities = 138/283 (48%), Positives = 188/283 (66%), Gaps = 10/283 (3%)

Query: 51  APSPYAQPSSTFDALSPS----PAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKK 106
           AP+P A P+    A +PS     ++PS   Y G + F + F  S TAKS T TYS  L K
Sbjct: 74  APAP-AAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNK 132

Query: 107 LYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAP 166
           ++CQ+AKTCP+Q+ V + PP G  +RAM +YK+++H+TEVV+RCP+HE  R  +   +AP
Sbjct: 133 MFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE--RCSDSDGLAP 190

Query: 167 PSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRP 226
           P HLIRVEGN   +Y++D  T R SV+VPYEPP+VG++ TT+ YN+MCNSSC+GGMNRRP
Sbjct: 191 PQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRP 250

Query: 227 ILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQ 286
           IL I+TLE   G +LGR  FE R+CACPGRDR+ +E+++RK+           TKR    
Sbjct: 251 ILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPN 310

Query: 287 NTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLEL 329
           NT     +   K++  D E   L +RGRE +EM  ++ E+LEL
Sbjct: 311 NT---SSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALEL 350


>gi|187830855 tumor protein p53 isoform b [Homo sapiens]
          Length = 341

 Score =  253 bits (645), Expect = 3e-67
 Identities = 124/242 (51%), Positives = 166/242 (68%), Gaps = 7/242 (2%)

Query: 51  APSPYAQPSSTFDALSPS----PAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKK 106
           AP+P A P+    A +PS     ++PS   Y G + F + F  S TAKS T TYS  L K
Sbjct: 74  APAP-AAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNK 132

Query: 107 LYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAP 166
           ++CQ+AKTCP+Q+ V + PP G  +RAM +YK+++H+TEVV+RCP+HE  R  +   +AP
Sbjct: 133 MFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE--RCSDSDGLAP 190

Query: 167 PSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRP 226
           P HLIRVEGN   +Y++D  T R SV+VPYEPP+VG++ TT+ YN+MCNSSC+GGMNRRP
Sbjct: 191 PQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRP 250

Query: 227 ILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQ 286
           IL I+TLE   G +LGR  FE R+CACPGRDR+ +E+++RK+           TKR    
Sbjct: 251 ILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPN 310

Query: 287 NT 288
           NT
Sbjct: 311 NT 312


>gi|187830823 tumor protein p53 isoform c [Homo sapiens]
          Length = 346

 Score =  253 bits (645), Expect = 3e-67
 Identities = 124/242 (51%), Positives = 166/242 (68%), Gaps = 7/242 (2%)

Query: 51  APSPYAQPSSTFDALSPS----PAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKK 106
           AP+P A P+    A +PS     ++PS   Y G + F + F  S TAKS T TYS  L K
Sbjct: 74  APAP-AAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNK 132

Query: 107 LYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAP 166
           ++CQ+AKTCP+Q+ V + PP G  +RAM +YK+++H+TEVV+RCP+HE  R  +   +AP
Sbjct: 133 MFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE--RCSDSDGLAP 190

Query: 167 PSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRP 226
           P HLIRVEGN   +Y++D  T R SV+VPYEPP+VG++ TT+ YN+MCNSSC+GGMNRRP
Sbjct: 191 PQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRP 250

Query: 227 ILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQ 286
           IL I+TLE   G +LGR  FE R+CACPGRDR+ +E+++RK+           TKR    
Sbjct: 251 ILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPN 310

Query: 287 NT 288
           NT
Sbjct: 311 NT 312


>gi|187830894 tumor protein p53 isoform d [Homo sapiens]
          Length = 261

 Score =  236 bits (603), Expect = 2e-62
 Identities = 113/223 (50%), Positives = 156/223 (69%), Gaps = 5/223 (2%)

Query: 107 LYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAP 166
           ++CQ+AKTCP+Q+ V + PP G  +RAM +YK+++H+TEVV+RCP+HE  R  +   +AP
Sbjct: 1   MFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE--RCSDSDGLAP 58

Query: 167 PSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRP 226
           P HLIRVEGN   +Y++D  T R SV+VPYEPP+VG++ TT+ YN+MCNSSC+GGMNRRP
Sbjct: 59  PQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRP 118

Query: 227 ILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQ 286
           IL I+TLE   G +LGR  FE R+CACPGRDR+ +E+++RK+           TKR    
Sbjct: 119 ILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPN 178

Query: 287 NTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLEL 329
           NT     +   K++  D E   L +RGRE +EM  ++ E+LEL
Sbjct: 179 NT---SSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALEL 218


>gi|187830909 tumor protein p53 isoform f [Homo sapiens]
          Length = 214

 Score =  216 bits (551), Expect = 2e-56
 Identities = 99/182 (54%), Positives = 134/182 (73%), Gaps = 2/182 (1%)

Query: 107 LYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAP 166
           ++CQ+AKTCP+Q+ V + PP G  +RAM +YK+++H+TEVV+RCP+HE  R  +   +AP
Sbjct: 1   MFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE--RCSDSDGLAP 58

Query: 167 PSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRP 226
           P HLIRVEGN   +Y++D  T R SV+VPYEPP+VG++ TT+ YN+MCNSSC+GGMNRRP
Sbjct: 59  PQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRP 118

Query: 227 ILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQ 286
           IL I+TLE   G +LGR  FE R+CACPGRDR+ +E+++RK+           TKR    
Sbjct: 119 ILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPN 178

Query: 287 NT 288
           NT
Sbjct: 179 NT 180


>gi|187830901 tumor protein p53 isoform e [Homo sapiens]
          Length = 209

 Score =  216 bits (551), Expect = 2e-56
 Identities = 99/182 (54%), Positives = 134/182 (73%), Gaps = 2/182 (1%)

Query: 107 LYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAP 166
           ++CQ+AKTCP+Q+ V + PP G  +RAM +YK+++H+TEVV+RCP+HE  R  +   +AP
Sbjct: 1   MFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE--RCSDSDGLAP 58

Query: 167 PSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRP 226
           P HLIRVEGN   +Y++D  T R SV+VPYEPP+VG++ TT+ YN+MCNSSC+GGMNRRP
Sbjct: 59  PQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRP 118

Query: 227 ILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQ 286
           IL I+TLE   G +LGR  FE R+CACPGRDR+ +E+++RK+           TKR    
Sbjct: 119 ILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPN 178

Query: 287 NT 288
           NT
Sbjct: 179 NT 180


>gi|239582749 sterile alpha motif domain containing 4 isoform 2
           [Homo sapiens]
          Length = 629

 Score = 34.7 bits (78), Expect = 0.15
 Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 1/80 (1%)

Query: 22  LLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPH 81
           LL S+++ I  G S   P    H Q  +T    Y+ PS+T +A    P  P      GP 
Sbjct: 297 LLKSLERDIIEGGSLRIPLQELH-QMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPE 355

Query: 82  SFDVSFQQSSTAKSATWTYS 101
           S     +  + A  AT T S
Sbjct: 356 SQSPDCKDGAAATGATATPS 375


>gi|239582747 sterile alpha motif domain containing 4 isoform 1
           [Homo sapiens]
          Length = 717

 Score = 34.7 bits (78), Expect = 0.15
 Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 1/80 (1%)

Query: 22  LLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPH 81
           LL S+++ I  G S   P    H Q  +T    Y+ PS+T +A    P  P      GP 
Sbjct: 385 LLKSLERDIIEGGSLRIPLQELH-QMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPE 443

Query: 82  SFDVSFQQSSTAKSATWTYS 101
           S     +  + A  AT T S
Sbjct: 444 SQSPDCKDGAAATGATATPS 463


>gi|206597502 NESH protein isoform 2 [Homo sapiens]
          Length = 360

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 37/144 (25%), Positives = 63/144 (43%), Gaps = 14/144 (9%)

Query: 27  DQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVS 86
           D ++   SS++S  +   A+    AP+P  Q      A  P+P +PS+ D P P +    
Sbjct: 193 DGRLSAASSASSLASAGSAEGVGGAPTPKGQ------AAPPAPPLPSSLDPPPPPAAVEV 246

Query: 87  FQQSSTAKSATWTYSTELKKLYCQIAKTCPIQ-IKVMTPPPQGAVIRAMPVYKKAEHVTE 145
           FQ+  T +  +     E   L   +    P+   ++  PPP        P +  A ++ +
Sbjct: 247 FQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPASYLEK 306

Query: 146 VVKRCP-----NHELSREFNEGQI 164
           VV   P     ++ELS  F+EG +
Sbjct: 307 VVTLYPYTSQKDNELS--FSEGTV 328


>gi|7705981 NESH protein isoform 1 [Homo sapiens]
          Length = 366

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 37/144 (25%), Positives = 63/144 (43%), Gaps = 14/144 (9%)

Query: 27  DQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVS 86
           D ++   SS++S  +   A+    AP+P  Q      A  P+P +PS+ D P P +    
Sbjct: 199 DGRLSAASSASSLASAGSAEGVGGAPTPKGQ------AAPPAPPLPSSLDPPPPPAAVEV 252

Query: 87  FQQSSTAKSATWTYSTELKKLYCQIAKTCPIQ-IKVMTPPPQGAVIRAMPVYKKAEHVTE 145
           FQ+  T +  +     E   L   +    P+   ++  PPP        P +  A ++ +
Sbjct: 253 FQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPASYLEK 312

Query: 146 VVKRCP-----NHELSREFNEGQI 164
           VV   P     ++ELS  F+EG +
Sbjct: 313 VVTLYPYTSQKDNELS--FSEGTV 334


>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
          Length = 1161

 Score = 33.9 bits (76), Expect = 0.26
 Identities = 20/73 (27%), Positives = 30/73 (41%), Gaps = 3/73 (4%)

Query: 324 KESLELMQYLPQHTIETYRQQQQQQHQHLLQKHLLSACFRNELVEPRRETPKQSDVFFRH 383
           ++  +  Q   Q   +  +QQQQQQH H    HLL   +  +     ++       F  H
Sbjct: 462 QQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMH 521

Query: 384 S---KPPNRSVYP 393
           S     P+ S YP
Sbjct: 522 SVYQPQPSASQYP 534


>gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens]
          Length = 662

 Score = 33.9 bits (76), Expect = 0.26
 Identities = 20/73 (27%), Positives = 30/73 (41%), Gaps = 3/73 (4%)

Query: 324 KESLELMQYLPQHTIETYRQQQQQQHQHLLQKHLLSACFRNELVEPRRETPKQSDVFFRH 383
           ++  +  Q   Q   +  +QQQQQQH H    HLL   +  +     ++       F  H
Sbjct: 462 QQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMH 521

Query: 384 S---KPPNRSVYP 393
           S     P+ S YP
Sbjct: 522 SVYQPQPSASQYP 534


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 33.5 bits (75), Expect = 0.34
 Identities = 46/196 (23%), Positives = 71/196 (36%), Gaps = 18/196 (9%)

Query: 8   AQTQFSEPQYTNLGLLNSMDQ------QIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSST 61
           AQT  S+ Q     L N ++       Q+     + SP +      S  A  P  Q ++ 
Sbjct: 777 AQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTP 836

Query: 62  FDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKV 121
                P PA P+    P   S         +  SAT T ST   +   Q   T   Q  V
Sbjct: 837 PGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPV 896

Query: 122 MTP---PPQGAVIRAMPVYKK------AEHVTEVVKR--CPNHELSREFNEGQIAPPSHL 170
             P    PQ +  +  PV+ +      ++    +  R   P+   S E N  Q  P   +
Sbjct: 897 QPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPV 956

Query: 171 IRVEGNSHAQYVE-DP 185
           + ++  + A+  E DP
Sbjct: 957 LEMKTETQAEDTEPDP 972


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 33.5 bits (75), Expect = 0.34
 Identities = 46/196 (23%), Positives = 71/196 (36%), Gaps = 18/196 (9%)

Query: 8    AQTQFSEPQYTNLGLLNSMDQ------QIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSST 61
            AQT  S+ Q     L N ++       Q+     + SP +      S  A  P  Q ++ 
Sbjct: 815  AQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTP 874

Query: 62   FDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKV 121
                 P PA P+    P   S         +  SAT T ST   +   Q   T   Q  V
Sbjct: 875  PGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPV 934

Query: 122  MTP---PPQGAVIRAMPVYKK------AEHVTEVVKR--CPNHELSREFNEGQIAPPSHL 170
              P    PQ +  +  PV+ +      ++    +  R   P+   S E N  Q  P   +
Sbjct: 935  QPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPV 994

Query: 171  IRVEGNSHAQYVE-DP 185
            + ++  + A+  E DP
Sbjct: 995  LEMKTETQAEDTEPDP 1010


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 33.1 bits (74), Expect = 0.45
 Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 21/114 (18%)

Query: 13   SEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIP 72
            S P  T + L  S+  ++ + + + +   + H Q + TAP+P+   +S    L PSPA+ 
Sbjct: 1332 STPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTS-TSQIPTLEPSPAL- 1389

Query: 73   SNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPP 126
                            +SS ++S+T   +T +  L  +  K    Q   +TPPP
Sbjct: 1390 ----------------ESSPSRSST---ATSMDPLSTEDFKPPRSQSPNLTPPP 1424


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 32.7 bits (73), Expect = 0.58
 Identities = 31/139 (22%), Positives = 66/139 (47%), Gaps = 9/139 (6%)

Query: 243 RRCFEARICACPGRDRKA--DEDSIRKQQVSDSTKNGDGTKRPFRQNTHG--IQMTSIKK 298
           RR  E ++ +C G + +   DE+ +R++++ +  + G   K+  R+       Q    K+
Sbjct: 186 RRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE 245

Query: 299 RRSPDDELLYLPVRGRETY-EMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKHL 357
            R  +  L     + +E   +   +++E  E ++ L +  +   RQ+++QQ Q L ++  
Sbjct: 246 WRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQ 305

Query: 358 LSACFRNELVEPRRETPKQ 376
           L    R +  E RRE  ++
Sbjct: 306 L----RRKQEEERREQQEE 320


>gi|58530840 desmoplakin isoform I [Homo sapiens]
          Length = 2871

 Score = 32.3 bits (72), Expect = 0.76
 Identities = 27/121 (22%), Positives = 55/121 (45%), Gaps = 15/121 (12%)

Query: 258  RKADEDSIRKQQVSDSTKNGDGTKRPFRQN-------THGIQMTSIKKRRSPDDELLYLP 310
            R A EDS +++++ +     +G +R  ++        T  ++  SI K+RS DD      
Sbjct: 1582 RTASEDSCKRKKLEEEL---EGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLR---- 1634

Query: 311  VRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKHLLSACFRNELVEPR 370
             + R+  +  L+ K+  +         +E  R+Q  Q+ + + Q HL +  F+  + +  
Sbjct: 1635 -QQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKS 1693

Query: 371  R 371
            R
Sbjct: 1694 R 1694


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
           sapiens]
          Length = 1293

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 2/104 (1%)

Query: 257 DRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGRET 316
           +R+ +E+  RKQ+     +  +  K  + +     Q    + R   ++E   L     E 
Sbjct: 819 ERRREEEERRKQEELLRKQEEEAAK--WAREEEEAQRRLEENRLRMEEEAARLRHEEEER 876

Query: 317 YEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKHLLSA 360
               L+++   ELM+   Q      R QQQQQ Q L Q  L S+
Sbjct: 877 KRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 920


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
           sapiens]
          Length = 1320

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 2/104 (1%)

Query: 257 DRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGRET 316
           +R+ +E+  RKQ+     +  +  K  + +     Q    + R   ++E   L     E 
Sbjct: 846 ERRREEEERRKQEELLRKQEEEAAK--WAREEEEAQRRLEENRLRMEEEAARLRHEEEER 903

Query: 317 YEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKHLLSA 360
               L+++   ELM+   Q      R QQQQQ Q L Q  L S+
Sbjct: 904 KRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 947


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.130    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,626,739
Number of Sequences: 37866
Number of extensions: 789026
Number of successful extensions: 3773
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 62
Number of HSP's that attempted gapping in prelim test: 3576
Number of HSP's gapped (non-prelim): 196
length of query: 393
length of database: 18,247,518
effective HSP length: 104
effective length of query: 289
effective length of database: 14,309,454
effective search space: 4135432206
effective search space used: 4135432206
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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