Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 112382270
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|112382270 matrix metalloproteinase 17 preproprotein [Homo
sapiens]
(603 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|112382270 matrix metalloproteinase 17 preproprotein [Homo sap... 1275 0.0
gi|11968059 matrix metalloproteinase 25 preproprotein [Homo sapi... 511 e-145
gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens] 385 e-107
gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens] 361 1e-99
gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens] 361 1e-99
gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein ... 358 1e-98
gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens] 283 4e-76
gi|58331148 matrix metalloproteinase 11 preproprotein [Homo sapi... 280 3e-75
gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens] 262 8e-70
gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens] 245 1e-64
gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprot... 244 2e-64
gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein... 241 1e-63
gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [H... 239 5e-63
gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens] 237 2e-62
gi|45359865 matrix metalloproteinase 20 preproprotein [Homo sapi... 234 2e-61
gi|73858572 matrix metalloproteinase 12 preproprotein [Homo sapi... 233 5e-61
gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens] 232 6e-61
gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein ... 216 4e-56
gi|73808268 matrix metalloproteinase 27 [Homo sapiens] 214 2e-55
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens] 181 2e-45
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [... 181 2e-45
gi|22218341 matrix metalloproteinase 21 preproprotein [Homo sapi... 170 3e-42
gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens] 158 1e-38
gi|73808266 matrix metalloproteinase 26 preproprotein [Homo sapi... 138 1e-32
gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens] 120 4e-27
gi|5902004 matrix metalloproteinase 23B precursor [Homo sapiens] 110 5e-24
gi|239750339 PREDICTED: hypothetical protein XP_002347374 [Homo ... 82 1e-15
gi|11321561 hemopexin precursor [Homo sapiens] 70 4e-12
gi|88853069 vitronectin precursor [Homo sapiens] 66 8e-11
gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens] 55 2e-07
>gi|112382270 matrix metalloproteinase 17 preproprotein [Homo
sapiens]
Length = 603
Score = 1275 bits (3299), Expect = 0.0
Identities = 603/603 (100%), Positives = 603/603 (100%)
Query: 1 MRRRAARGPGPPPPGPGLSRLPLPLLLLLALGTRGGCAAPAPAPRAEDLSLGVEWLSRFG 60
MRRRAARGPGPPPPGPGLSRLPLPLLLLLALGTRGGCAAPAPAPRAEDLSLGVEWLSRFG
Sbjct: 1 MRRRAARGPGPPPPGPGLSRLPLPLLLLLALGTRGGCAAPAPAPRAEDLSLGVEWLSRFG 60
Query: 61 YLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQ 120
YLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQ
Sbjct: 61 YLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQ 120
Query: 121 ARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAG 180
ARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAG
Sbjct: 121 ARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAG 180
Query: 181 SAADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGM 240
SAADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGM
Sbjct: 181 SAADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGM 240
Query: 241 DLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESV 300
DLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESV
Sbjct: 241 DLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESV 300
Query: 301 SPTAQPEEPPLLPEPPDNRSSAPPRKDVPHRCSTHFDAVAQIRGEAFFFKGKYFWRLTRD 360
SPTAQPEEPPLLPEPPDNRSSAPPRKDVPHRCSTHFDAVAQIRGEAFFFKGKYFWRLTRD
Sbjct: 301 SPTAQPEEPPLLPEPPDNRSSAPPRKDVPHRCSTHFDAVAQIRGEAFFFKGKYFWRLTRD 360
Query: 361 RHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRP 420
RHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRP
Sbjct: 361 RHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRP 420
Query: 421 VSDFSLPPGGIDAAFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQSPLWRGVPSTLD 480
VSDFSLPPGGIDAAFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQSPLWRGVPSTLD
Sbjct: 421 VSDFSLPPGGIDAAFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQSPLWRGVPSTLD 480
Query: 481 DAMRWSDGASYFFRGQEYWKVLDGELEVAPGYPQSTARDWLVCGDSQADGSVAAGVDAAE 540
DAMRWSDGASYFFRGQEYWKVLDGELEVAPGYPQSTARDWLVCGDSQADGSVAAGVDAAE
Sbjct: 481 DAMRWSDGASYFFRGQEYWKVLDGELEVAPGYPQSTARDWLVCGDSQADGSVAAGVDAAE 540
Query: 541 GPRAPPGQHDQSRSEDGYEVCSCTSGASSPPGAPGPLVAATMLLLLPPLSPGALWTAAQA 600
GPRAPPGQHDQSRSEDGYEVCSCTSGASSPPGAPGPLVAATMLLLLPPLSPGALWTAAQA
Sbjct: 541 GPRAPPGQHDQSRSEDGYEVCSCTSGASSPPGAPGPLVAATMLLLLPPLSPGALWTAAQA 600
Query: 601 LTL 603
LTL
Sbjct: 601 LTL 603
>gi|11968059 matrix metalloproteinase 25 preproprotein [Homo
sapiens]
Length = 562
Score = 511 bits (1317), Expect = e-145
Identities = 274/581 (47%), Positives = 347/581 (59%), Gaps = 34/581 (5%)
Query: 20 RLPLPLLLLLALGTRGGCAAPAPAPRAEDLSLGVEWLSRFGYLPPADPTTGQLQTQEELS 79
RL L LLLL L A AP P A+D+SLGV+WL+R+GYLPP P QLQ+ E+L
Sbjct: 4 RLRLLALLLLLLAP----PARAPKPSAQDVSLGVDWLTRYGYLPPPHPAQAQLQSPEKLR 59
Query: 80 KAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQA--RRRRQAPAPTKWNKRN 137
AI MQ+F GL TG +D T+A M+ PRCSLPD+ + RRRR A + + W KR
Sbjct: 60 DAIKVMQRFAGLPETGRMDPGTVATMRKPRCSLPDVLGVAGLVRRRRRYALSGSVWKKRT 119
Query: 138 LSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEV---AGSAADIQIDFSKADH 194
L+WRVR+FP+ S L +TVR LM YAL W + L FHEV G DI IDF++A H
Sbjct: 120 LTWRVRSFPQSSQLSQETVRVLMSYALMAWGMESGLTFHEVDSPQGQEPDILIDFARAFH 179
Query: 195 NDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAI 254
D YPFDG GGT+AHAFFPG H +GDTHFDD+E WTF S D G DLFAVAVHEFGHA+
Sbjct: 180 QDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFGSKDGEGTDLFAVAVHEFGHAL 239
Query: 255 GLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESVSPTAQPEEPPLLPE 314
GL H +A +SIMRP+YQGPVGDP +Y L +D+ + QLYG + +P +P PL P
Sbjct: 240 GLGHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLYG-KAPQTPYDKPTRKPLAPP 298
Query: 315 P-PDNRSSAPPRKDVPHRCSTHFDAVAQIRGEAFFFKGKYFWRLTRDRHLVSLQPAQMHR 373
P P + P +P RC +FDA+A IRGE FFFKG +FWRL LVS +PA++HR
Sbjct: 299 PQPPASPTHSPSFPIPDRCEGNFDAIANIRGETFFFKGPWFWRLQPSGQLVSPRPARLHR 358
Query: 374 FWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPVSDFSLPPG-GID 432
FW GLP + V A Y R D +I+ F G ++WVF+D +E G RP+++ LPPG +D
Sbjct: 359 FWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQDRQLEGG-ARPLTELGLPPGEEVD 417
Query: 433 AAFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQSPLWRGVPSTLDDAMRWSDGASYF 492
A FSW N +TY + + YWRYD+ DPGYP LW G P + DD + G +YF
Sbjct: 418 AVFSWPQNGKTYLVRGRQYWRYDEAAARPDPGYPRDLSLWEGAPPSPDDVTVSNAGDTYF 477
Query: 493 FRGQEYWKVLDGELEVAPGYPQSTARDWLVCGDSQADGSVAAGVDAAEGPRAPPGQHDQS 552
F+G YW+ ++ P PQ +WL C + ++G A P+A P
Sbjct: 478 FKGAHYWRFPKNSIKTEPDAPQPMGPNWLDC------PAPSSGPRAPRPPKATPVS---- 527
Query: 553 RSEDGYEVCSCTSGASSPPGA-PGPLVAATMLLLLPPLSPG 592
E C C + G P P+ LLLLP L G
Sbjct: 528 ------ETCDCQCELNQAAGRWPAPI----PLLLLPLLVGG 558
>gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]
Length = 645
Score = 385 bits (989), Expect = e-107
Identities = 227/580 (39%), Positives = 308/580 (53%), Gaps = 66/580 (11%)
Query: 4 RAARGPGPPPPGPGLS------RLPLPLLLLL------------------ALGTRGGCA- 38
RAA GP PPPP PG + R+P LLLLL G R A
Sbjct: 8 RAAPGPPPPPPPPGQAPRWSRWRVPGRLLLLLLPALCCLPGAARAAAAAAGAGNRAAVAV 67
Query: 39 APAPAPRAEDLSLGVEWLSRFGYLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILD 98
A A A AE G WL +GYL P D L + + L A++ MQQF G+ TG+LD
Sbjct: 68 AVARADEAEAPFAGQNWLKSYGYLLPYDSRASALHSAKALQSAVSTMQQFYGIPVTGVLD 127
Query: 99 EATLALMKTPRCSLPDLPVLTQARR-RRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVR 157
+ T+ MK PRC +PD P L++ RR +R A KW ++++++ + + +G R
Sbjct: 128 QTTIEWMKKPRCGVPDHPHLSRRRRNKRYALTGQKWRQKHITYSIHNY--TPKVGELDTR 185
Query: 158 ALMYYALKVWSDIAPLNFHEVA-------GSAADIQIDFSKADHNDGYPFDGPGGTVAHA 210
+ A VW + PL F EV ADI I F+ H D PFDG GG +AHA
Sbjct: 186 KAIRQAFDVWQKVTPLTFEEVPYHEIKSDRKEADIMIFFASGFHGDSSPFDGEGGFLAHA 245
Query: 211 FFPGHHHTAGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYY 270
+FPG GDTHFD DE WT +++ G DLF VAVHE GHA+GL H + +IM P+Y
Sbjct: 246 YFPG-PGIGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHALGLEHSSDPSAIMAPFY 304
Query: 271 QGPVGDPLRYGLPYEDKVRVWQLYG----------------VRESVSPTAQP-EEPPLLP 313
Q + + LP +D + ++YG VR SP+ + E P P
Sbjct: 305 Q--YMETHNFKLPQDDLQGIQKIYGPPAEPLEPTRPLPTLPVRRIHSPSERKHERQPRPP 362
Query: 314 EPP-DNRSSAPPRKDVPHRCSTHFDAVAQIRGEAFFFKGKYFWRLTRDRHLVSLQPAQMH 372
PP +R S P K P+ C +F+ VA RGE F FK ++FWRL R+ + P Q+
Sbjct: 363 RPPLGDRPSTPGTK--PNICDGNFNTVALFRGEMFVFKDRWFWRL-RNNRVQEGYPMQIE 419
Query: 373 RFWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPVSDFS--LPPGG 430
+FW+GLP +DA YER +D + VFFKGD+YWVFK+ VE GYP + + LP G
Sbjct: 420 QFWKGLPAR---IDAAYER-ADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSCLPREG 475
Query: 431 IDAAFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQSPLWRGVPSTLDDAMRWSDG-A 489
ID A W +TYFFK + YWRY + R DPGYP +W+G+P A +G
Sbjct: 476 IDTALRWEPVGKTYFFKGERYWRYSEERRATDPGYPKPITVWKGIPQAPQGAFISKEGYY 535
Query: 490 SYFFRGQEYWKVLDGELEVAPGYPQSTARDWLVCGDSQAD 529
+YF++G++YWK + +L V PGYP++ RDW+ C + +
Sbjct: 536 TYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGCNQKEVE 575
>gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]
Length = 582
Score = 361 bits (926), Expect = 1e-99
Identities = 208/535 (38%), Positives = 295/535 (55%), Gaps = 49/535 (9%)
Query: 9 PGPPPPGPGLSRLPLPLLLL-LALGTRGGCAAPAPAPRAEDLSLGVEWLSRFGYLPPADP 67
P P PP L LPLL L AL + G + + +P A WL ++GYLPP D
Sbjct: 3 PAPRPP----RCLLLPLLTLGTALASLGSAQSSSFSPEA--------WLQQYGYLPPGDL 50
Query: 68 TTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPD---LPVLTQARRR 124
T ++ + LS AI AMQ+F GL+ TG D T+ M+ PRC +PD + RR+
Sbjct: 51 RTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRK 110
Query: 125 RQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGS--- 181
R A KW +++ ++ + +G + A +VW PL F EV +
Sbjct: 111 RYAIQGLKWQHNEITFCIQNYT--PKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIR 168
Query: 182 -----AADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSD 236
ADI I F++ H D PFDG GG +AHA+FPG + GDTHFD E WT R+ D
Sbjct: 169 EGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPN-IGGDTHFDSAEPWTVRNED 227
Query: 237 AHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGV 296
+G D+F VAVHE GHA+GL H + +IM P+YQ D + LP +D+ + QLYG
Sbjct: 228 LNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWM--DTENFVLPDDDRRGIQQLYG- 284
Query: 297 RESVSPTAQPEEP-----PLLPEPPDNRSSAPPRKDVPHRCSTHFDAVAQIRGEAFFFKG 351
ES PT P +P P +P+ P N + P+ C +FD VA +RGE F FK
Sbjct: 285 GESGFPTKMPPQPRTTSRPSVPDKPKNPTYG------PNICDGNFDTVAMLRGEMFVFKE 338
Query: 352 KYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDN 411
++FWR+ R+ ++ P + +FWRGLP S++ YER D K VFFKGD++WVF +
Sbjct: 339 RWFWRV-RNNQVMDGYPMPIGQFWRGLPA---SINTAYER-KDGKFVFFKGDKHWVFDEA 393
Query: 412 NVEEGYPRPVSDF--SLPPGGIDAAFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQS 469
++E GYP+ + + LP IDAA W N +TYFF+ Y+R+++ R +D YP
Sbjct: 394 SLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNI 453
Query: 470 PLWRGVPSTLDDAMRWSDGA-SYFFRGQEYWKVLDGELEVAPGYPQSTARDWLVC 523
+W G+P + + SD +YF++G +YWK + +L+V PGYP+S RDW+ C
Sbjct: 454 KVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGC 508
>gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]
Length = 669
Score = 361 bits (926), Expect = 1e-99
Identities = 218/580 (37%), Positives = 301/580 (51%), Gaps = 78/580 (13%)
Query: 23 LPLLLLLALGTRGGCAAPAPAPRAEDLSLGVE-WLSRFGYLPPADPTTGQLQTQEELSKA 81
LPLLL+L GC A AED + E WL +GYLP +++ + L+ A
Sbjct: 30 LPLLLVLL-----GCLGLGVA--AEDAEVHAENWLRLYGYLPQPSRHMSTMRSAQILASA 82
Query: 82 ITAMQQFGGLEATGILDEATLALMKTPRCSLPD---LPVLTQARRRRQAPAPT--KWNKR 136
+ MQ+F G+ TG+LDE T MK PRC +PD + V RRRR+ A T KWN
Sbjct: 83 LAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVRVKANLRRRRKRYALTGRKWNNH 142
Query: 137 NLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVA--------GSAADIQID 188
+L++ ++ + LG + A +VW PL F EV ADI +
Sbjct: 143 HLTFSIQNYTEK--LGWYHSMEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADIMVL 200
Query: 189 FSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGMDLFAVAVH 248
F+ H D PFDG GG +AHA+FPG GDTHFD DE WTF S+D HG +LF VAVH
Sbjct: 201 FASGFHGDSSPFDGTGGFLAHAYFPGPG-LGGDTHFDADEPWTFSSTDLHGNNLFLVAVH 259
Query: 249 EFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESVS------P 302
E GHA+GL H + ++IM P+YQ D + LP +D + QLYG + P
Sbjct: 260 ELGHALGLEHSSNPNAIMAPFYQWK--DVDNFKLPEDDLRGIQQLYGTPDGQPQPTQPLP 317
Query: 303 TAQPEEP---------PLLPEPPDNRSSAPPRKDV--------------PHRCSTHFDAV 339
T P P P P PP + PP+ P+ C FD V
Sbjct: 318 TVTPRRPGRPDHRPPRPPQPPPPGGKPERPPKPGPPVQPRATERPDQYGPNICDGDFDTV 377
Query: 340 AQIRGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVF 399
A +RGE F FKG++FWR+ +R ++ P + FWRGLP + A YER D + VF
Sbjct: 378 AMLRGEMFVFKGRWFWRVRHNR-VLDNYPMPIGHFWRGLP---GDISAAYER-QDGRFVF 432
Query: 400 FKGDRYWVFKDNNVEEGYPRPVSDFSL--PPGGIDAAFSWAHNDRTYFFKDQLYWRYDDH 457
FKGDRYW+F++ N+E GYP+P++ + L P ID A W T+FF++ YWR+++
Sbjct: 433 FKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFFFQEDRYWRFNEE 492
Query: 458 TRHMDPGYPAQSPLWRGVPSTLDDAMRWSDGA-SYFFRGQEYWKVLDGELEVAPGYPQST 516
T+ DPGYP +W+G+P++ A +D A +YF++G +YWK + L + PGYP+S
Sbjct: 493 TQRGDPGYPKPISVWQGIPASPKGAFLSNDAAYTYFYKGTKYWKFDNERLRMEPGYPKSI 552
Query: 517 ARDWLVCGDS---------------QADGSVAAGVDAAEG 541
RD++ C + G G D+AEG
Sbjct: 553 LRDFMGCQEHVEPGPRWPDVARPPFNPHGGAEPGADSAEG 592
>gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein
[Homo sapiens]
Length = 607
Score = 358 bits (918), Expect = 1e-98
Identities = 196/499 (39%), Positives = 274/499 (54%), Gaps = 42/499 (8%)
Query: 55 WLSRFGYLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPD 114
WL ++GYLPP DP L++ E + A+ AMQQF G+ TG +D T+ MK PRC +PD
Sbjct: 46 WLQKYGYLPPTDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPD 105
Query: 115 L---PVLTQARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIA 171
RR+R A KW +++++ ++ +G R + A VW ++
Sbjct: 106 QTRGSSKFHIRRKRYALTGQKWQHKHITYSIKNV--TPKVGDPETRKAIRRAFDVWQNVT 163
Query: 172 PLNFHEVAGSA-------ADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHF 224
PL F EV S DI I F+ H D PFDG GG +AHA+FPG GDTHF
Sbjct: 164 PLTFEEVPYSELENGKRDVDITIIFASGFHGDSSPFDGEGGFLAHAYFPG-PGIGGDTHF 222
Query: 225 DDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPY 284
D DE WT + + G DLF VAVHE GHA+GL H +IM P+YQ D + LP
Sbjct: 223 DSDEPWTLGNPNHDGNDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETD--NFKLPN 280
Query: 285 EDKVRVWQLYGVRESVSPTAQP-----------------EEPPLLPEPPDNRSSAPPRKD 327
+D + ++YG + + P +P + P P PP R S P K
Sbjct: 281 DDLQGIQKIYGPPDKIPPPTRPLPTVPPHRSIPPADPRKNDRPKPPRPPTGRPSYPGAK- 339
Query: 328 VPHRCSTHFDAVAQIRGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDA 387
P+ C +F+ +A +R E F FK ++FWR+ R+ ++ P Q+ FWRGLP S+DA
Sbjct: 340 -PNICDGNFNTLAILRREMFVFKDQWFWRV-RNNRVMDGYPMQITYFWRGLP---PSIDA 394
Query: 388 VYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPVSDF--SLPPGGIDAAFSWAHNDRTYF 445
VYE SD VFFKG++YWVFKD ++ GYP + +PP GID+A W +TYF
Sbjct: 395 VYE-NSDGNFVFFKGNKYWVFKDTTLQPGYPHDLITLGSGIPPHGIDSAIWWEDVGKTYF 453
Query: 446 FKDQLYWRYDDHTRHMDPGYPAQSPLWRGVPSTLDDA-MRWSDGASYFFRGQEYWKVLDG 504
FK YWRY + + MDPGYP +W+G+P + A + +G +YF++G+EYWK +
Sbjct: 454 FKGDRYWRYSEEMKTMDPGYPKPITVWKGIPESPQGAFVHKENGFTYFYKGKEYWKFNNQ 513
Query: 505 ELEVAPGYPQSTARDWLVC 523
L+V PGYP+S +D++ C
Sbjct: 514 ILKVEPGYPRSILKDFMGC 532
>gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]
Length = 477
Score = 283 bits (723), Expect = 4e-76
Identities = 190/519 (36%), Positives = 258/519 (49%), Gaps = 63/519 (12%)
Query: 23 LPLLLLLALGTRGGCAAPA--PAPRAEDLSLGV--EWLSRFGYLPPADPTTGQLQTQEEL 78
LP+LLLL + C+A A R ED S+ + ++L + L + + +
Sbjct: 4 LPILLLLCVAV---CSAYPLDGAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPV 60
Query: 79 SKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQARRRRQAPAPTKWNKRNL 138
K I MQ+F GLE TG LD TL +M+ PRC +PD+ R P KW K +L
Sbjct: 61 VKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHF------RTFPGIPKWRKTHL 114
Query: 139 SWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQIDFSKADHNDGY 198
++R+ + D P D V + + ALKVW ++ PL F + ADI I F+ +H D Y
Sbjct: 115 TYRIVNYTPDLP--KDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFY 172
Query: 199 PFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSH 258
PFDGPG +AHA+ PG GD HFDDDE WT D G +LF VA HE GH++GL H
Sbjct: 173 PFDGPGNVLAHAYAPG-PGINGDAHFDDDEQWT---KDTTGTNLFLVAAHEIGHSLGLFH 228
Query: 259 VAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESVSPTAQPEEPPLLPEPPDN 318
A ++M P Y + D R+ L +D + LYG P E PL+P P
Sbjct: 229 SANTEALMYPLYHS-LTDLTRFRLSQDDINGIQSLYG------PPPDSPETPLVPTEP-- 279
Query: 319 RSSAPPRKDVPHRC--STHFDAVAQIRGEAFFFKGKYFWR-----LTRDRHLVSLQPAQM 371
PP P C + FDAV+ +RGE FK ++FWR L + HL+S
Sbjct: 280 ---VPPEPGTPANCDPALSFDAVSTLRGEILIFKDRHFWRKSLRKLEPELHLIS------ 330
Query: 372 HRFWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPVSDFSLPP--G 429
FW LP VDA YE TS + FKG+++W + N V GYPR + PP
Sbjct: 331 -SFWPSLP---SGVDAAYEVTSKDLVFIFKGNQFWAIRGNEVRAGYPRGIHTLGFPPTVR 386
Query: 430 GIDAAFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQ-SPLWRGVPSTLDDAMRWSDG 488
IDAA S ++TYFF + YWR+D+ M+PG+P Q + + G+ S + DA+ G
Sbjct: 387 KIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEPGFPKQIAEDFPGIDSKI-DAVFEEFG 445
Query: 489 ASYFFRGQEYWKVLDGELEVAPGYPQST----ARDWLVC 523
YFF G +LE P + T + WL C
Sbjct: 446 FFYFFTG-------SSQLEFDPNAKKVTHTLKSNSWLNC 477
>gi|58331148 matrix metalloproteinase 11 preproprotein [Homo
sapiens]
Length = 488
Score = 280 bits (716), Expect = 3e-75
Identities = 172/428 (40%), Positives = 225/428 (52%), Gaps = 27/428 (6%)
Query: 105 MKTPRCSLPDLPVLTQARRRRQ--APAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYY 162
++ PRC +PD AR R++ + +W K +L++R+ FP L + VR M
Sbjct: 75 LRPPRCGVPDPSDGLSARNRQKRFVLSGGRWEKTDLTYRILRFPWQ--LVQEQVRQTMAE 132
Query: 163 ALKVWSDIAPLNFHEVAGSAADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDT 222
ALKVWSD+ PL F EV ADI IDF++ H D PFDGPGG +AHAFFP H GD
Sbjct: 133 ALKVWSDVTPLTFTEVHEGRADIMIDFARYWHGDDLPFDGPGGILAHAFFP-KTHREGDV 191
Query: 223 HFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRY-- 280
HFD DE WT D G DL VA HEFGH +GL H AA ++M +Y RY
Sbjct: 192 HFDYDETWTI--GDDQGTDLLQVAAHEFGHVLGLQHTTAAKALMSAFY------TFRYPL 243
Query: 281 GLPYEDKVRVWQLYGVRESVSPTAQPEEPPLLPEPP-DNRSSAPPRKDV-PHRCSTHFDA 338
L +D V LYG PT P L P+ D AP D P C FDA
Sbjct: 244 SLSPDDCRGVQHLYG---QPWPTVTSRTPALGPQAGIDTNEIAPLEPDAPPDACEASFDA 300
Query: 339 VAQIRGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIV 398
V+ IRGE FFFK + WRL R L PA R W+GLP VDA +E H I
Sbjct: 301 VSTIRGELFFFKAGFVWRL-RGGQLQPGYPALASRHWQGLP---SPVDAAFEDAQGH-IW 355
Query: 399 FFKGDRYWVFKDNNVEEGYPRPVSDFSLPPGGIDAAFSWA-HNDRTYFFKDQLYWRYDDH 457
FF+G +YWV+ G P P+++ L + AA W ++ YFF+ + YWR+
Sbjct: 356 FFQGAQYWVYDGEKPVLG-PAPLTELGLVRFPVHAALVWGPEKNKIYFFRGRDYWRFHPS 414
Query: 458 TRHMDPGYPAQSPLWRGVPSTLDDAMRWSDGASYFFRGQEYWKVLDGELEVAPGYPQSTA 517
TR +D P ++ WRGVPS +D A + +DG +YF RG+ YWK +++ G+P+
Sbjct: 415 TRRVDSPVPRRATDWRGVPSEIDAAFQDADGYAYFLRGRLYWKFDPVKVKALEGFPRLVG 474
Query: 518 RDWLVCGD 525
D+ C +
Sbjct: 475 PDFFGCAE 482
>gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]
Length = 476
Score = 262 bits (669), Expect = 8e-70
Identities = 163/431 (37%), Positives = 228/431 (52%), Gaps = 45/431 (10%)
Query: 80 KAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQARRRRQAPAPTKWNKRNLS 139
K I MQ+F GLE TG LD TL +M+ PRC +PD+ + P KW K +L+
Sbjct: 61 KKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSF------PGMPKWRKTHLT 114
Query: 140 WRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQIDFSKADHNDGYP 199
+R+ + D P D V + + ALKVW ++ PL F + ADI I F+ +H D Y
Sbjct: 115 YRIVNYTPDLP--RDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYS 172
Query: 200 FDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHV 259
FDGPG ++AHA+ PG GD HFDDDE WT DA G +LF VA HE GH++GL H
Sbjct: 173 FDGPGHSLAHAYPPG-PGLYGDIHFDDDEKWT---EDASGTNLFLVAAHELGHSLGLFHS 228
Query: 260 AAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESVSPTAQPEEPPLLPEPPDNR 319
A ++M P Y + ++ L +D + LYG P A EE PL+P
Sbjct: 229 ANTEALMYPLYNS-FTELAQFRLSQDDVNGIQSLYG-----PPPASTEE-PLVP-----T 276
Query: 320 SSAPPRKDVPHRC--STHFDAVAQIRGEAFFFKGKYFWRLTR-----DRHLVSLQPAQMH 372
S P ++P +C + FDA++ +RGE FFK +YFWR + + HL+S
Sbjct: 277 KSVPSGSEMPAKCDPALSFDAISTLRGEYLFFKDRYFWRRSHWNPEPEFHLIS------- 329
Query: 373 RFWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPVSDFSLPP--GG 430
FW LP +L DA YE S + FKG+ +W + N V+ GYPR + PP
Sbjct: 330 AFWPSLPSYL---DAAYEVNSRDTVFIFKGNEFWAIRGNEVQAGYPRGIHTLGFPPTIRK 386
Query: 431 IDAAFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQ-SPLWRGVPSTLDDAMRWSDGA 489
IDAA S +TYFF YWR+D++++ M+ G+P + + GV + DA+ + G
Sbjct: 387 IDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQGFPRLIADDFPGVEPKV-DAVLQAFGF 445
Query: 490 SYFFRGQEYWK 500
YFF G ++
Sbjct: 446 FYFFSGSSQFE 456
>gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]
Length = 471
Score = 245 bits (625), Expect = 1e-64
Identities = 158/455 (34%), Positives = 213/455 (46%), Gaps = 48/455 (10%)
Query: 47 EDLSLGVEWLSRFGYLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMK 106
EDL +L + Y P + +++ + MQ F GLE TG LD+ TL +MK
Sbjct: 34 EDLQFAERYLRSY-YHPTNLAGILKENAASSMTERLREMQSFFGLEVTGKLDDNTLDVMK 92
Query: 107 TPRCSLPDLPVLTQARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKV 166
PRC +PD+ P KW+K NL++R+ + D + H V A KV
Sbjct: 93 KPRCGVPDVG------EYNVFPRTLKWSKMNLTYRIVNYTPD--MTHSEVEKAFKKAFKV 144
Query: 167 WSDIAPLNFHEVAGSAADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDD 226
WSD+ PLNF + ADI I F +H D YPFDGP G +AHAF PG ++ GD HFDD
Sbjct: 145 WSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNY-GGDAHFDD 203
Query: 227 DEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYED 286
DE WT S + G +LF VA HEFGH++GL H ++M P Y + LP +D
Sbjct: 204 DETWT---SSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIY--TYTGKSHFMLPDDD 258
Query: 287 KVRVWQLYGVRESVSPTAQPEEPPLLPEPPDNRSSAPPRKDVPHRC--STHFDAVAQIRG 344
+ LYG P + P P +C S DA+ +RG
Sbjct: 259 VQGIQSLYG--------------------PGDEDPNPKHPKTPDKCDPSLSLDAITSLRG 298
Query: 345 EAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKGDR 404
E FK ++FWRL + V + FW LP + +DA YE S I F+G +
Sbjct: 299 ETMIFKDRFFWRLHPQQ--VDAELFLTKSFWPELP---NRIDAAYEHPSHDLIFIFRGRK 353
Query: 405 YWVFKDNNVEEGYPRPVSDFSLPP--GGIDAAFSWAHNDRTYFFKDQLYWRYDDHTRHMD 462
+W ++ EGYP+ +S+ LP I AA + +T F WRYDD MD
Sbjct: 354 FWALNGYDILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMD 413
Query: 463 PGYPAQSPLWRGVPSTLD--DAMRWSDGASYFFRG 495
YP + P D DA+ +G YFF G
Sbjct: 414 KDYPRL--IEEDFPGIGDKVDAVYEKNGYIYFFNG 446
>gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprotein
[Homo sapiens]
Length = 508
Score = 244 bits (622), Expect = 2e-64
Identities = 164/496 (33%), Positives = 249/496 (50%), Gaps = 41/496 (8%)
Query: 53 VEWLSRFGYLPPADPTTGQLQTQ-EELSKAITAMQQFGGLEATGILDEATLALMKTPRCS 111
V++LS++GYL P G + E++++A+ A Q+ L +G LD+AT A M+ PRC
Sbjct: 29 VDYLSQYGYLQK--PLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCG 86
Query: 112 LPDLPVLTQARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIA 171
L D ++ + +W K++L++R+ P S L T RA + A + WS++A
Sbjct: 87 LED----PFNQKTLKYLLLGRWRKKHLTFRILNLP--STLPPHTARAALRQAFQDWSNVA 140
Query: 172 PLNFHEVAGSAADIQIDF-SKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAW 230
PL F EV AADI++ F + FDGPG +AHA P G HFD+DE W
Sbjct: 141 PLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIP----ELGSVHFDEDEFW 196
Query: 231 TFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRV 290
T G++L +A HE GHA+GL H + ++M P Y+ G + L +D +
Sbjct: 197 T--EGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYE---GYRPHFKLHPDDVAGI 251
Query: 291 WQLYGVRESVSPTAQPEEPPLLPEPPDNRSSAPPRKDVPHRCSTHFDA-VAQIRGEAFFF 349
LYG + V + EE L PP +P +P CS+ DA + RG+ + F
Sbjct: 252 QALYGKKSPVIRDEEEEETELPTVPPVPTEPSP----MPDPCSSELDAMMLGPRGKTYAF 307
Query: 350 KGKYFWRLTRDRHLVSLQPAQMHR---FWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYW 406
KG Y W ++ P + R W GLP +LD+ AVY + I FFKGD+ W
Sbjct: 308 KGDYVWTVS------DSGPGPLFRVSALWEGLPGNLDA--AVYSPRTQW-IHFFKGDKVW 358
Query: 407 VFKDNNVEEGYPRPVSDFSLPPGGIDAAFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYP 466
+ + + G+P+ ++ +DAA W N + + FK YW++D+ R YP
Sbjct: 359 RYINFKMSPGFPKKLNRVE---PNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYP 415
Query: 467 AQ-SPLWRGVPSTLDDAMRWSDGASYFFRGQEYWKVLDGELEVAPGYPQSTARDWLVCGD 525
L+ GVP+ AM W DG YFF+G+ YW+ L+ +L V GYP++ + +W+ C
Sbjct: 416 KPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKVYWR-LNQQLRVEKGYPRNISHNWMHCRP 474
Query: 526 SQADGSVAAGVDAAEG 541
D + + G G
Sbjct: 475 RTIDTTPSGGNTTPSG 490
>gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein
[Homo sapiens]
Length = 457
Score = 241 bits (616), Expect = 1e-63
Identities = 146/385 (37%), Positives = 200/385 (51%), Gaps = 41/385 (10%)
Query: 55 WLSRFGYLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPD 114
WL ++GYLPP DP L++ E + A+ AMQQF G+ TG +D T+ MK PRC +PD
Sbjct: 46 WLQKYGYLPPTDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPD 105
Query: 115 L---PVLTQARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIA 171
RR+R A KW +++++ ++ +G R + A VW ++
Sbjct: 106 QTRGSSKFHIRRKRYALTGQKWQHKHITYSIKNV--TPKVGDPETRKAIRRAFDVWQNVT 163
Query: 172 PLNFHEVAGSA-------ADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHF 224
PL F EV S DI I F+ H D PFDG GG +AHA+FPG GDTHF
Sbjct: 164 PLTFEEVPYSELENGKRDVDITIIFASGFHGDSSPFDGEGGFLAHAYFPG-PGIGGDTHF 222
Query: 225 DDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPY 284
D DE WT + + G DLF VAVHE GHA+GL H +IM P+YQ D + LP
Sbjct: 223 DSDEPWTLGNPNHDGNDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETD--NFKLPN 280
Query: 285 EDKVRVWQLYGVRESVSPTAQP-----------------EEPPLLPEPPDNRSSAPPRKD 327
+D + ++YG + + P +P + P P PP R S P K
Sbjct: 281 DDLQGIQKIYGPPDKIPPPTRPLPTVPPHRSIPPADPRKNDRPKPPRPPTGRPSYPGAK- 339
Query: 328 VPHRCSTHFDAVAQIRGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDA 387
P+ C +F+ +A +R E F FK ++FWR+ R+ ++ P Q+ FWRGLP S+DA
Sbjct: 340 -PNICDGNFNTLAILRREMFVFKDQWFWRV-RNNRVMDGYPMQITYFWRGLP---PSIDA 394
Query: 388 VYERTSDHKIVFF--KGDRYWVFKD 410
VYE SD VFF KGD + +D
Sbjct: 395 VYE-NSDGNFVFFKVKGDTLSIIQD 418
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/52 (44%), Positives = 32/52 (61%), Gaps = 3/52 (5%)
Query: 444 YFFKDQLYWRYDDHTRHMDPGYPAQ-SPLWRGVPSTLDDAMRWSDGASYFFR 494
+ FKDQ +WR ++ R MD GYP Q + WRG+P ++D SDG FF+
Sbjct: 358 FVFKDQWFWRVRNN-RVMD-GYPMQITYFWRGLPPSIDAVYENSDGNFVFFK 407
>gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [Homo
sapiens]
Length = 469
Score = 239 bits (610), Expect = 5e-63
Identities = 167/485 (34%), Positives = 237/485 (48%), Gaps = 52/485 (10%)
Query: 24 PLLLLLALGTRGGCAAPAPAPRAEDLSLGVEWLSRFGYLPPADPTTGQLQTQEELSKAIT 83
PLLLLL G + +D+ L ++L ++ L + + + + +
Sbjct: 6 PLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPVVEKLK 65
Query: 84 AMQQFGGLEATGILDEATLALMKTPRCSLPDLP--VLTQARRRRQAPAPTKWNKRNLSWR 141
MQ+F GL+ TG D TL +MK PRC +PD+ VLT+ R W + +L++R
Sbjct: 66 QMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPR--------WEQTHLTYR 117
Query: 142 VRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQIDFSKADHNDGYPFD 201
+ + D P V + A ++WS++ PL F +V+ ADI I F + DH D PFD
Sbjct: 118 IENYTPDLPRAD--VDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFD 175
Query: 202 GPGGTVAHAFFPGHHHTAGDTHFDDDEAWT--FRSSDAHGMDLFAVAVHEFGHAIGLSHV 259
GPGG +AHAF PG GD HFD+DE WT FR + H VA HE GH++GLSH
Sbjct: 176 GPGGNLAHAFQPG-PGIGGDAHFDEDERWTNNFREYNLH-----RVAAHELGHSLGLSHS 229
Query: 260 AAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESVSPTAQPEEPPLLPEPPDNR 319
++M P Y GD L +D + +YG +Q P+ P+ P
Sbjct: 230 TDIGALMYPSYTFS-GD---VQLAQDDIDGIQAIYG-------RSQNPVQPIGPQTPKAC 278
Query: 320 SSAPPRKDVPHRCSTHFDAVAQIRGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLP 379
S FDA+ IRGE FFK +++ R V L + FW LP
Sbjct: 279 DS-----------KLTFDAITTIRGEVMFFKDRFYMRTNPFYPEVELNFISV--FWPQLP 325
Query: 380 LHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPV-SDFSLP--PGGIDAAFS 436
+ ++A YE ++ FFKG++YW + NV GYP+ + S F P IDAA S
Sbjct: 326 ---NGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALS 382
Query: 437 WAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQ-SPLWRGVPSTLDDAMRWSDGASYFFRG 495
+ +TYFF YWRYD++ R MDPGYP + + G+ + DA+ DG YFF G
Sbjct: 383 EENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHKV-DAVFMKDGFFYFFHG 441
Query: 496 QEYWK 500
+K
Sbjct: 442 TRQYK 446
>gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]
Length = 467
Score = 237 bits (605), Expect = 2e-62
Identities = 159/483 (32%), Positives = 237/483 (49%), Gaps = 52/483 (10%)
Query: 23 LPLLLLLALGTRGGCAAPAPAPRAEDLSLGVEWLSRFGYLPPADPTTGQLQTQEELSKAI 82
LP LLLL + + + + ++L +F LP + + + + +
Sbjct: 7 LPFLLLLHVQISKAFPVSSKEKNTKTVQ---DYLEKFYQLPSNQYQSTRKNGTNVIVEKL 63
Query: 83 TAMQQFGGLEATGILDEATLALMKTPRCSLPDLP--VLTQARRRRQAPAPTKWNKRNLSW 140
MQ+F GL TG +E TL +MK PRC +PD +LT P KW + NL++
Sbjct: 64 KEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLT--------PGNPKWERTNLTY 115
Query: 141 RVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQIDFSKADHNDGYPF 200
R+R + L V + A ++WS +PL F ++ ADI I F + DH D PF
Sbjct: 116 RIRNYTPQ--LSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPF 173
Query: 201 DGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVA 260
DGP G +AHAF PG GD HFD +E WT S++ +LF VA HEFGH++GL+H +
Sbjct: 174 DGPNGILAHAFQPG-QGIGGDAHFDAEETWTNTSAN---YNLFLVAAHEFGHSLGLAHSS 229
Query: 261 AAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRES-VSPTAQPEEPPLLPEPPDNR 319
++M P Y + Y LP +D + +YG+ + + PT P P+P D
Sbjct: 230 DPGALMYPNY--AFRETSNYSLPQDDIDGIQAIYGLSSNPIQPTG-----PSTPKPCDP- 281
Query: 320 SSAPPRKDVPHRCSTHFDAVAQIRGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLP 379
S FDA+ +RGE FFK +YFWR R L ++ + FW LP
Sbjct: 282 -------------SLTFDAITTLRGEILFFKDRYFWR--RHPQLQRVEMNFISLFWPSLP 326
Query: 380 LHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPVSDFSLPPG--GIDAAFSW 437
+ A YE I FKG++YW ++ +GYP+ +S++ P IDAA
Sbjct: 327 ---TGIQAAYEDFDRDLIFLFKGNQYWALSGYDILQGYPKDISNYGFPSSVQAIDAAV-- 381
Query: 438 AHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQ-SPLWRGVPSTLDDAMRWSDGASYFFRGQ 496
+ +TYFF + +WRYD+ + M+PGYP S + G+ S + DA+ + + F G
Sbjct: 382 FYRSKTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGIESKV-DAVFQQEHFFHVFSGP 440
Query: 497 EYW 499
Y+
Sbjct: 441 RYY 443
>gi|45359865 matrix metalloproteinase 20 preproprotein [Homo
sapiens]
Length = 483
Score = 234 bits (596), Expect = 2e-61
Identities = 169/510 (33%), Positives = 244/510 (47%), Gaps = 46/510 (9%)
Query: 25 LLLLLALGTRGGCAAP---APAPRA--EDLSLGVEWLSRFGYLPPADPTTGQLQTQ--EE 77
L + L + + AAP A +PR + L +L ++ Y G++ +
Sbjct: 9 LAVFLIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKY-YTNKEGHQIGEMVARGSNS 67
Query: 78 LSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQARRRRQAPAPTKWNKRN 137
+ + I +Q F GL+ TG LD+ T+ ++K PRC +PD+ R P KW K
Sbjct: 68 MIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVA------NYRLFPGEPKWKKNT 121
Query: 138 LSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQIDFSKADHNDG 197
L++R+ + + V + AL+ WS PL+F + ADI I F DH D
Sbjct: 122 LTYRISKYTPS--MSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDS 179
Query: 198 YPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLS 257
YPFDGP GT+AHAF PG GDTHFD+ E WT +G +LF VA HEFGHA+GL+
Sbjct: 180 YPFDGPRGTLAHAFAPG-EGLGGDTHFDNAEKWTM---GTNGFNLFTVAAHEFGHALGLA 235
Query: 258 HVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESVSPTAQPEEPPLLPEPPD 317
H ++M P Y+ +P + LP +D + LYG R+ P LP P
Sbjct: 236 HSTDPSALMYPTYK--YKNPYGFHLPKDDVKGIQALYGPRKVFL------GKPTLPHAPH 287
Query: 318 NRSSAPPRKDVPHRCSTHFDAVAQIRGEAFFFKGKYFWRLTRDRHL-VSLQPAQMHRFWR 376
++ S P D S+ FDAV + E FK + FWR R HL ++P+ +
Sbjct: 288 HKPSIPDLCD----SSSSFDAVTMLGKELLLFKDRIFWR--RQVHLRTGIRPSTI---TS 338
Query: 377 GLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPVSDFSLP--PGGIDAA 434
P + +VDA YE FFKG YW+ + + +G PR + DF P IDAA
Sbjct: 339 SFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQM-QGPPRTIYDFGFPRHVQQIDAA 397
Query: 435 FSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQS-PLWRGVPSTLDDAMRWSDGASYFF 493
+T FF Y+ YD+ R M+ YP + + GV +D A+ +G YFF
Sbjct: 398 VYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQIDAAVE-LNGYIYFF 456
Query: 494 RGQEYWKVLDGELEVAPGYPQSTARDWLVC 523
G + +K D E E +S++ W+ C
Sbjct: 457 SGPKTYK-YDTEKEDVVSVVKSSS--WIGC 483
>gi|73858572 matrix metalloproteinase 12 preproprotein [Homo
sapiens]
Length = 470
Score = 233 bits (593), Expect = 5e-61
Identities = 155/484 (32%), Positives = 232/484 (47%), Gaps = 45/484 (9%)
Query: 25 LLLLLALGTRGGCAAPAPAPRAE--DLSLGVEWLSRF-GYLPPADPTTGQLQTQEELSKA 81
LL+LL T G + E ++ G +L +F G P T + + +
Sbjct: 4 LLILLLQATASGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLMKEK 63
Query: 82 ITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQARRRRQAPAPTKWNKRNLSWR 141
I MQ F GL+ TG LD +TL +M PRC +PD+ R+ P W K +++R
Sbjct: 64 IQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDV------HHFREMPGGPVWRKHYITYR 117
Query: 142 VRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQIDFSKADHNDGYPFD 201
+ + D + + V + A +VWS++ PL F ++ ADI + F++ H D + FD
Sbjct: 118 INNYTPD--MNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFD 175
Query: 202 GPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAA 261
G GG +AHAF PG GD HFD+DE WT S G +LF AVHE GH++GL H +
Sbjct: 176 GKGGILAHAFGPG-SGIGGDAHFDEDEFWTTHSG---GTNLFLTAVHEIGHSLGLGHSSD 231
Query: 262 AHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESVSPTAQPEEPPLLPEPPDNRSS 321
++M P Y+ D + L +D + LYG P+E LP P ++
Sbjct: 232 PKAVMFPTYK--YVDINTFRLSADDIRGIQSLYG---------DPKENQRLPNPDNSE-- 278
Query: 322 APPRKDVPHRCSTH--FDAVAQIRGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLP 379
P C + FDAV + + FFFK ++FW +R S+ + W LP
Sbjct: 279 -------PALCDPNLSFDAVTTVGNKIFFFKDRFFWLKVSERPKTSVN--LISSLWPTLP 329
Query: 380 LHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPVSDFSLP--PGGIDAAFSW 437
++A YE + +++ FK D+YW+ + E YP+ + F P IDAA
Sbjct: 330 ---SGIEAAYEIEARNQVFLFKDDKYWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFN 386
Query: 438 AHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQ-SPLWRGVPSTLDDAMRWSDGASYFFRGQ 496
RTYFF D YWRYD+ + MDPGYP + ++G+ +D + YFF+G
Sbjct: 387 PRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGIGPKIDAVFYSKNKYYYFFQGS 446
Query: 497 EYWK 500
++
Sbjct: 447 NQFE 450
>gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]
Length = 403
Score = 232 bits (592), Expect = 6e-61
Identities = 156/424 (36%), Positives = 214/424 (50%), Gaps = 52/424 (12%)
Query: 85 MQQFGGLEATGILDEATLALMKTPRCSLPDLP--VLTQARRRRQAPAPTKWNKRNLSWRV 142
MQ+F GL+ TG D TL +MK PRC +PD+ VLT+ R W + +L++R+
Sbjct: 1 MQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPR--------WEQTHLTYRI 52
Query: 143 RTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQIDFSKADHNDGYPFDG 202
+ D P V + A ++WS++ PL F +V+ ADI I F + DH D PFDG
Sbjct: 53 ENYTPDLPRAD--VDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDG 110
Query: 203 PGGTVAHAFFPGHHHTAGDTHFDDDEAWT--FRSSDAHGMDLFAVAVHEFGHAIGLSHVA 260
PGG +AHAF PG GD HFD+DE WT FR + H VA HE GH++GLSH
Sbjct: 111 PGGNLAHAFQPG-PGIGGDAHFDEDERWTNNFREYNLH-----RVAAHELGHSLGLSHST 164
Query: 261 AAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESVSPTAQPEEPPLLPEPPDNRS 320
++M P Y GD L +D + +YG +Q P+ P+ P
Sbjct: 165 DIGALMYPSYTFS-GD---VQLAQDDIDGIQAIYG-------RSQNPVQPIGPQTPKACD 213
Query: 321 SAPPRKDVPHRCSTHFDAVAQIRGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPL 380
S FDA+ IRGE FFK +++ R V L + FW LP
Sbjct: 214 S-----------KLTFDAITTIRGEVMFFKDRFYMRTNPFYPEVELNFISV--FWPQLP- 259
Query: 381 HLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPV-SDFSLP--PGGIDAAFSW 437
+ ++A YE ++ FFKG++YW + NV GYP+ + S F P IDAA S
Sbjct: 260 --NGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSE 317
Query: 438 AHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQ-SPLWRGVPSTLDDAMRWSDGASYFFRGQ 496
+ +TYFF YWRYD++ R MDPGYP + + G+ + DA+ DG YFF G
Sbjct: 318 ENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHKV-DAVFMKDGFFYFFHGT 376
Query: 497 EYWK 500
+K
Sbjct: 377 RQYK 380
>gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein
[Homo sapiens]
Length = 520
Score = 216 bits (551), Expect = 4e-56
Identities = 158/492 (32%), Positives = 225/492 (45%), Gaps = 43/492 (8%)
Query: 55 WLSRFGYLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPD 114
+L ++GYL P + T S AI A Q L +G+LD ATL M PRC + D
Sbjct: 39 FLEKYGYLNEQVP---KAPTSTRFSDAIRAFQWVSQLPVSGVLDRATLRQMTRPRCGVTD 95
Query: 115 LPVLT----------------QARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRA 158
R++R A KW K++LS+R+ +P P VR
Sbjct: 96 TNSYAAWAERISDLFARHRTKMRRKKRFAKQGNKWYKQHLSYRLVNWPEHLP--EPAVRG 153
Query: 159 LMYYALKVWSDIAPLNFHEV-AGSAADIQIDFSKADHNDGY--PFDGPGGTVAHAFFPGH 215
+ A ++WS+++ L F E A ADI++ F + DHNDG FDGPGG +AHAF P
Sbjct: 154 AVRAAFQLWSNVSALEFWEAPATGPADIRLTFFQGDHNDGLGNAFDGPGGALAHAFLPRR 213
Query: 216 HHTAGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVG 275
G+ HFD DE W+ S G +LF V HE GH +GL+H A ++M PYY+
Sbjct: 214 ----GEAHFDQDERWSL--SRRRGRNLFVVLAHEIGHTLGLTHSPAPRALMAPYYKRLGR 267
Query: 276 DPLRYGLPYEDKVRVWQLYGVRESVSPTAQ-PEEPPLLPEPPDNRSSAPPRKDV--PHRC 332
D L L ++D + V LYG S Q P + E D+ S R + P C
Sbjct: 268 DAL---LSWDDVLAVQSLYGKPLGGSVAVQLPGKLFTDFETWDSYSPQGRRPETQGPKYC 324
Query: 333 STHFDAVAQIRGEAFF-FKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYER 391
+ FDA+ R + + FKG +FW + D ++ +P Q W GLP +++A
Sbjct: 325 HSSFDAITVDRQQQLYIFKGSHFWEVAADGNVSEPRPLQER--WVGLP---PNIEAAAVS 379
Query: 392 TSDHKIVFFKGDRYWVFKDNNVEEGYPRPVSDFSLPPGGIDAAFSWAHNDRTYFFKDQLY 451
+D FFKG R W F+ G P+ LP DAA + R FK Y
Sbjct: 380 LNDGDFYFFKGGRCWRFRGPKPVWGLPQLCRAGGLPRHP-DAALFFPPLRRLILFKGARY 438
Query: 452 WRYDDHTRHMDPGYPAQSPLWRGVPSTLDDAMRWSDGASYFFRGQEYWKVLDGELEVAPG 511
+ ++P YP W G+P + A+ DG+ FFR YW++ +L+
Sbjct: 439 YVLARGGLQVEPYYPRSLQDWGGIPEEVSGALPRPDGSIIFFRDDRYWRLDQAKLQATTS 498
Query: 512 YPQSTARDWLVC 523
+T W+ C
Sbjct: 499 GRWATELPWMGC 510
>gi|73808268 matrix metalloproteinase 27 [Homo sapiens]
Length = 513
Score = 214 bits (544), Expect = 2e-55
Identities = 152/460 (33%), Positives = 218/460 (47%), Gaps = 48/460 (10%)
Query: 47 EDLSLGVEWLSRFGYLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMK 106
E++ L +L++F L Q + + + I MQ F GL TG LD TL +MK
Sbjct: 28 ENMQLAQAYLNQFYSLEIEGNHLVQSKNRSLIDDKIREMQAFFGLTVTGKLDSNTLEIMK 87
Query: 107 TPRCSLPDLPVLTQARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKV 166
TPRC +PD+ + W K NL++R+ + D + V + L+V
Sbjct: 88 TPRCGVPDV--------GQYGYTLPGWRKYNLTYRIINYTPD--MARAAVDEAIQEGLEV 137
Query: 167 WSDIAPLNFHEVAGSAADIQIDFSKADHND-GYPFDGPGGTVAHAFFPGHHHTAGDTHFD 225
WS + PL F +++ ADI I F H FDGP G + HAF PG GDTHFD
Sbjct: 138 WSKVTPLKFTKISKGIADIMIAFRTRVHGRCPRYFDGPLGVLGHAFPPG-PGLGGDTHFD 196
Query: 226 DDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYE 285
+DE WT D G +LF VA HEFGHA+GLSH ++M P Y DP +Y L +
Sbjct: 197 EDENWT---KDGAGFNLFLVAAHEFGHALGLSHSNDQTALMFPNYVSL--DPRKYPLSQD 251
Query: 286 DKVRVWQLYGVRESVSPTAQPEEPPLLPEPPDNRSSAPPRKDVPHRCSTH--FDAVAQIR 343
D + +YG P+EP + P +PH C FDA+ R
Sbjct: 252 DINGIQSIYG--------GLPKEP-----------AKPKEPTIPHACDPDLTFDAITTFR 292
Query: 344 GEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKGD 403
E FFKG++ WR+ D + ++ + FW LP L A YE D KI+ FK +
Sbjct: 293 REVMFFKGRHLWRIYYD--ITDVEFELIASFWPSLPADL---QAAYENPRD-KILVFKDE 346
Query: 404 RYWVFKDNNVEEGYPRPVSDFSLP--PGGIDAAFSWAHNDRTYFFKDQLYWRYDDHTRHM 461
+W+ + V YP+ + P IDAA +TYFF WR+D+ T+ M
Sbjct: 347 NFWMIRGYAVLPDYPKSIHTLGFPGRVKKIDAAVCDKTTRKTYFFVGIWCWRFDEMTQTM 406
Query: 462 DPGYPAQ-SPLWRGVPSTLDDAMRWSDGASYFFRGQEYWK 500
D G+P + + G+ +D A ++ G +F RG + ++
Sbjct: 407 DKGFPQRVVKHFPGISIRVDAAFQYK-GFFFFSRGSKQFE 445
>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
Length = 610
Score = 181 bits (459), Expect = 2e-45
Identities = 109/309 (35%), Positives = 155/309 (50%), Gaps = 28/309 (9%)
Query: 219 AGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPL 278
A ++DDD W F G LF VA HEFGHA+GL H ++M P Y
Sbjct: 326 ATTANYDDDRKWGFCPDQ--GYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKN--- 380
Query: 279 RYGLPYEDKVRVWQLYGVRESVSPTAQPEEPPLLPEPPDNRSSAPPRKDVPHRCSTHFDA 338
+ L +D + +LYG + P P L P P+ ++D+ FD
Sbjct: 381 -FRLSQDDIKGIQELYGASPDIDLGTGPT-PTLGPVTPEIC-----KQDIV------FDG 427
Query: 339 VAQIRGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIV 398
+AQIRGE FFFK ++ WR R + P + FW LP + +DAVYE + K V
Sbjct: 428 IAQIRGEIFFFKDRFIWRTVTPRDK-PMGPLLVATFWPELP---EKIDAVYEAPQEEKAV 483
Query: 399 FFKGDRYWVFKDNNVEEGYPRPVSDFSLPPG--GIDAAFSWAHNDRTYFFKDQLYWRYDD 456
FF G+ YW++ + +E GYP+P++ LPP +DAAF+W+ N +TY F +WRY++
Sbjct: 484 FFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNE 543
Query: 457 HTRHMDPGYPAQ-SPLWRGVPSTLDDAMRWSDGA-SYFFRGQEYWKVLDGELEVAPGYPQ 514
+ MDPG+P + W +P LD + G SYFF+G Y K+ + L+
Sbjct: 544 VKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKF--G 601
Query: 515 STARDWLVC 523
S DWL C
Sbjct: 602 SIKSDWLGC 610
Score = 121 bits (303), Expect = 2e-27
Identities = 64/154 (41%), Positives = 85/154 (55%), Gaps = 9/154 (5%)
Query: 78 LSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQARRRRQAPAPTKWNKRN 137
L + MQ+F GL TG LD+ T+ M+ PRC PD+ P KW+K
Sbjct: 20 LKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVA------NYNFFPRKPKWDKNQ 73
Query: 138 LSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQIDFSKADHNDG 197
+++R+ + D L +TV A +VWSD+ PL F + ADI I+F + +H DG
Sbjct: 74 ITYRIIGYTPD--LDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDG 131
Query: 198 YPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWT 231
YPFDG G +AHAF PG GD+HFDDDE WT
Sbjct: 132 YPFDGKDGLLAHAFAPG-TGVGGDSHFDDDELWT 164
>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
[Homo sapiens]
Length = 660
Score = 181 bits (459), Expect = 2e-45
Identities = 109/309 (35%), Positives = 155/309 (50%), Gaps = 28/309 (9%)
Query: 219 AGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPL 278
A ++DDD W F G LF VA HEFGHA+GL H ++M P Y
Sbjct: 376 ATTANYDDDRKWGFCPDQ--GYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKN--- 430
Query: 279 RYGLPYEDKVRVWQLYGVRESVSPTAQPEEPPLLPEPPDNRSSAPPRKDVPHRCSTHFDA 338
+ L +D + +LYG + P P L P P+ ++D+ FD
Sbjct: 431 -FRLSQDDIKGIQELYGASPDIDLGTGPT-PTLGPVTPEIC-----KQDIV------FDG 477
Query: 339 VAQIRGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIV 398
+AQIRGE FFFK ++ WR R + P + FW LP + +DAVYE + K V
Sbjct: 478 IAQIRGEIFFFKDRFIWRTVTPRDK-PMGPLLVATFWPELP---EKIDAVYEAPQEEKAV 533
Query: 399 FFKGDRYWVFKDNNVEEGYPRPVSDFSLPPG--GIDAAFSWAHNDRTYFFKDQLYWRYDD 456
FF G+ YW++ + +E GYP+P++ LPP +DAAF+W+ N +TY F +WRY++
Sbjct: 534 FFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNE 593
Query: 457 HTRHMDPGYPAQ-SPLWRGVPSTLDDAMRWSDGA-SYFFRGQEYWKVLDGELEVAPGYPQ 514
+ MDPG+P + W +P LD + G SYFF+G Y K+ + L+
Sbjct: 594 VKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKF--G 651
Query: 515 STARDWLVC 523
S DWL C
Sbjct: 652 SIKSDWLGC 660
Score = 126 bits (317), Expect = 5e-29
Identities = 81/218 (37%), Positives = 108/218 (49%), Gaps = 24/218 (11%)
Query: 22 PLPLLLLLALGTRGGCAAPAP--------APRAEDLSLGVEWLSRFGYLPPADPTTGQLQ 73
PL L LL AAP+P AP+ D L V++L+ F P L+
Sbjct: 13 PLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKT-DKELAVQYLNTFYGCPKESCNLFVLK 71
Query: 74 TQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQARRRRQAPAPTKW 133
+ MQ+F GL TG LD+ T+ M+ PRC PD+ P KW
Sbjct: 72 D------TLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVA------NYNFFPRKPKW 119
Query: 134 NKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQIDFSKAD 193
+K +++R+ + D L +TV A +VWSD+ PL F + ADI I+F + +
Sbjct: 120 DKNQITYRIIGYTPD--LDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWE 177
Query: 194 HNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWT 231
H DGYPFDG G +AHAF PG GD+HFDDDE WT
Sbjct: 178 HGDGYPFDGKDGLLAHAFAPG-TGVGGDSHFDDDELWT 214
>gi|22218341 matrix metalloproteinase 21 preproprotein [Homo
sapiens]
Length = 569
Score = 170 bits (431), Expect = 3e-42
Identities = 150/531 (28%), Positives = 233/531 (43%), Gaps = 104/531 (19%)
Query: 40 PAPAPRAE---DLSLGVEWLSRFGYLP------PADPTTGQLQTQEELSKAITAMQQFGG 90
P+P +A+ DL +LSR+G+ P+ + L++A+ Q+
Sbjct: 38 PSPLRQAKPIADLHAAQRFLSRYGWSGVWAAWGPSPEGPPETPKGAALAEAVRRFQRANA 97
Query: 91 LEATGILDEATLALMKTPRCSLPDL--------------PVLTQARRRRQAP-------- 128
L A+G LD ATLA M PRC +PD+ P ++RR +AP
Sbjct: 98 LPASGELDAATLAAMNRPRCGVPDMRPPPPSAPPSPPGPPPRARSRRSPRAPLSLSRRGW 157
Query: 129 ---------APTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHE-- 177
A ++KR LSWR+ S L R ++ A ++WS++ PL+F E
Sbjct: 158 QPRGYPDGGAAQAFSKRTLSWRLLGEALSSQLSVADQRRIVALAFRMWSEVTPLDFREDL 217
Query: 178 -VAGSAADIQIDFSKADHNDGYP--FDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRS 234
G+A DI++ F + H G P FDG G AHA+ GD HFDDDE +T +
Sbjct: 218 AAPGAAVDIKLGFGRGRHL-GCPRAFDGSGQEFAHAW------RLGDIHFDDDEHFTPPT 270
Query: 235 SDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLY 294
SD G+ L VAVHE GH +GL H SIM+P Y + + L + D+ + +LY
Sbjct: 271 SDT-GISLLKVAVHEIGHVLGLPHTYRTGSIMQPNY---IPQEPAFELDWSDRKAIQKLY 326
Query: 295 GVRESVSPTAQPEEPPLLPEPPDNRSSAPPRKDVPHRCSTHFDAVAQIRGEAFFFKGKYF 354
G E TA D + + V +R +FF+ ++
Sbjct: 327 GSCEGSFDTA---------------------FDWIRKERNQYGEV-MVRFSTYFFRNSWY 364
Query: 355 WRL-TRDRHLVSLQPAQMHRFWRGLPLH-LDSVDAVYERTSDHKIVFFKGDRYWVF---K 409
W R+ P Q+ W G+P H +D+ ++ D + FF+G++YW + K
Sbjct: 365 WLYENRNNRTRYGDPIQILTGWPGIPTHNIDAFVHIWTWKRDER-YFFQGNQYWRYDSDK 423
Query: 410 DNNVEE-----GYPRPVSD-FSLPPGGIDAAFSWAHNDRTYFFKDQLYWRYDDHTRHMDP 463
D + E YP+ +S+ F P +D AF YFFK+ L + +D + +
Sbjct: 424 DQALTEDEQGKSYPKLISEGFPGIPSPLDTAFYDRRQKLIYFFKESLVFAFDVNRNRVLN 483
Query: 464 GYP-----------AQSPLWRGVPSTLDDAMRWSDGASYFFRGQEYWKVLD 503
YP Q+ +R + S ++ + +FF+G YWKV++
Sbjct: 484 SYPKRITEVFPAVIPQNHPFRNIDSAY---YSYAYNSIFFFKGNAYWKVVN 531
>gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]
Length = 267
Score = 158 bits (400), Expect = 1e-38
Identities = 90/258 (34%), Positives = 134/258 (51%), Gaps = 13/258 (5%)
Query: 42 PAPRAEDLSLGVEWLSRFGYLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILDEAT 101
P P+ ++W YL + + L + MQ+F GL TG+L+
Sbjct: 19 PLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRV 78
Query: 102 LALMKTPRCSLPDLPVLTQARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMY 161
+ +M+ PRC +PD+ + P KW + +++R+ ++ RD P H TV L+
Sbjct: 79 IEIMQKPRCGVPDVAEYSLF------PNSPKWTSKVVTYRIVSYTRDLP--HITVDRLVS 130
Query: 162 YALKVWSDIAPLNFHEVAGSAADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGD 221
AL +W PL+F +V ADI I F++ H D YPFDGPG T+AHAF PG GD
Sbjct: 131 KALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPG-TGLGGD 189
Query: 222 THFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYG 281
HFD+DE WT SS G++ A HE GH++G+ H + +++M P Y GDP +
Sbjct: 190 AHFDEDERWTDGSS--LGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGN--GDPQNFK 245
Query: 282 LPYEDKVRVWQLYGVRES 299
L +D + +LYG R +
Sbjct: 246 LSQDDIKGIQKLYGKRSN 263
>gi|73808266 matrix metalloproteinase 26 preproprotein [Homo
sapiens]
Length = 261
Score = 138 bits (348), Expect = 1e-32
Identities = 82/224 (36%), Positives = 116/224 (51%), Gaps = 18/224 (8%)
Query: 72 LQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQARRRRQAPAPT 131
L TQE ++ + + G T +LD AL+ P C +PD +P
Sbjct: 48 LLTQETQTQLLQQFHRNG----TDLLDMQMHALLHQPHCGVPD------GSDTSISPGRC 97
Query: 132 KWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQIDFSK 191
KWNK L++R+ +P D + V+ +Y A+ +WS++ PL F +V ADI++ F +
Sbjct: 98 KWNKHTLTYRIINYPHD--MKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQ 155
Query: 192 ADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFG 251
H DG+PFDGPGG + HAF P + G HFD +E W S+ G +LF VA HE G
Sbjct: 156 WAHEDGWPFDGPGGILGHAFLP-NSGNPGVVHFDKNEHW---SASDTGYNLFLVATHEIG 211
Query: 252 HAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYG 295
H++GL H SIM P Y DP + L +D R+ LYG
Sbjct: 212 HSLGLQHSGNQSSIMYPTYW--YHDPRTFQLSADDIQRIQHLYG 253
>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
Length = 707
Score = 120 bits (301), Expect = 4e-27
Identities = 80/224 (35%), Positives = 105/224 (46%), Gaps = 32/224 (14%)
Query: 22 PLPLLLLLALGTRGGCAAPAPAPRAE--------------DLSLGVEWLSRFGYLPPADP 67
PL L+LL+ GC AP R D L E+L R+GY A+
Sbjct: 6 PLVLVLLVL-----GCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYRYGYTRVAE- 59
Query: 68 TTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQARRRRQA 127
+ L A+ +Q+ L TG LD ATL M+TPRC +PDL R +
Sbjct: 60 ---MRGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLG------RFQTF 110
Query: 128 PAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQI 187
KW+ N+++ ++ + D P + A +WS + PL F V ADI I
Sbjct: 111 EGDLKWHHHNITYWIQNYSEDLPRA--VIDDAFARAFALWSAVTPLTFTRVYSRDADIVI 168
Query: 188 DFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWT 231
F A+H DGYPFDG G +AHAF PG GD HFDDDE W+
Sbjct: 169 QFGVAEHGDGYPFDGKDGLLAHAFPPG-PGIQGDAHFDDDELWS 211
Score = 106 bits (265), Expect = 5e-23
Identities = 91/324 (28%), Positives = 134/324 (41%), Gaps = 56/324 (17%)
Query: 219 AGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPL 278
A ++FD D+ W F G LF VA HEFGHA+GL H + ++M P Y+ G PL
Sbjct: 374 ATTSNFDSDKKWGFCPDQ--GYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPL 431
Query: 279 RYGLPYEDKVRVWQLYGVRESVSP------TAQPEEPPLL------------------PE 314
+D + LYG R P T QP PP +
Sbjct: 432 H----KDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTG 487
Query: 315 PPDNRSSAPPR-----------KDVPHRCSTH-FDAVAQIRGEAFFFKGKYFWRLTRDRH 362
PP + PP V C+ + FDA+A+I + + FK +WR + R
Sbjct: 488 PPSAGPTGPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRG 547
Query: 363 LVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPVS 422
P + W LP LDS V+E K+ FF G + WV+ +V PR +
Sbjct: 548 SRPQGPFLIADKWPALPRKLDS---VFEERLSKKLFFFSGRQVWVYTGASVLG--PRRLD 602
Query: 423 DFSLPPGGIDAA----FSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQ-SPLWRGVPS 477
L G D A + + F + WR+D + +DP ++ ++ GVP
Sbjct: 603 KLGL---GADVAQVTGALRSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPL 659
Query: 478 TLDDAMRWSDGASYFFRGQEYWKV 501
D ++ + A YF + + YW+V
Sbjct: 660 DTHDVFQYREKA-YFCQDRFYWRV 682
>gi|5902004 matrix metalloproteinase 23B precursor [Homo sapiens]
Length = 390
Score = 110 bits (274), Expect = 5e-24
Identities = 71/182 (39%), Positives = 97/182 (53%), Gaps = 19/182 (10%)
Query: 98 DEATLALMKTPRCSLPDLPVLTQARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVR 157
D A L L P +P P+ + RR PA +W+ NL++R+ +FPR+ +T R
Sbjct: 54 DVAALGLSAVPPTRVPG-PLAPRRRRYTLTPARLRWDHFNLTYRILSFPRNLLSPRETRR 112
Query: 158 ALMYYALKVWSDIAPLNFHEVA-GSAADIQIDFSKADHND------GYPFDGPGGTVAHA 210
AL A ++WSD++P +F EVA +D++I F +H D + FDGP G +AHA
Sbjct: 113 ALA-AAFRMWSDVSPFSFREVAPEQPSDLRIGFYPINHTDCLVSALHHCFDGPTGELAHA 171
Query: 211 FFPGHHHTAGDTHFDDDEAWTF---RSSDAHGM---DLFAVAVHEFGHAIGLSHVAAAHS 264
FFP H G HFDD E W R S G+ DL VA HE GHA+GL H +
Sbjct: 172 FFPPH----GGIHFDDSEYWVLGPTRYSWKKGVWLTDLVHVAAHEIGHALGLMHSQHGRA 227
Query: 265 IM 266
+M
Sbjct: 228 LM 229
>gi|239750339 PREDICTED: hypothetical protein XP_002347374 [Homo
sapiens]
Length = 183
Score = 82.4 bits (202), Expect = 1e-15
Identities = 54/154 (35%), Positives = 84/154 (54%), Gaps = 10/154 (6%)
Query: 53 VEWLSRFGYLPPADPTTGQLQTQ-EELSKAITAMQQFGGLEATGILDEATLALMKTPRCS 111
V++LS++GYL P G + E++++A+ A Q+ L +G LD+AT A M+ PRC
Sbjct: 29 VDYLSQYGYLQK--PLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCG 86
Query: 112 LPDLPVLTQARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIA 171
L D ++ + +W K++L++R+ P S L T RA + A + WS++A
Sbjct: 87 LED----PFNQKTLKYLLLGRWRKKHLTFRILNLP--STLPPHTARAALRQAFQDWSNVA 140
Query: 172 PLNFHEVAGSAADIQIDF-SKADHNDGYPFDGPG 204
PL F EV AADI++ F + FDGPG
Sbjct: 141 PLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPG 174
>gi|11321561 hemopexin precursor [Homo sapiens]
Length = 462
Score = 70.5 bits (171), Expect = 4e-12
Identities = 61/209 (29%), Positives = 89/209 (42%), Gaps = 28/209 (13%)
Query: 324 PRKDVPHRCST--HFDAVA-QIRGEAFFFKGKYFWRLTR-DRHLVSLQPAQMHRFWRGLP 379
P DV RCS FDA G FFKG++ W+ + DR L+S + W+ P
Sbjct: 42 PDPDVTERCSDGWSFDATTLDDNGTMLFFKGEFVWKSHKWDRELISER-------WKNFP 94
Query: 380 LHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPVSD-FSLPPGGIDAAFSW- 437
VDA + R + + KGD+ WV+ E+GYP+ + D F P +DAA
Sbjct: 95 ---SPVDAAF-RQGHNSVFLIKGDKVWVYPPEKKEKGYPKLLQDEFPGIPSPLDAAVECH 150
Query: 438 ---AHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQSPLWRGVPSTLDDAMRWSDGASYFFR 494
+ FF+ W +D T M + W V A+RW G Y F+
Sbjct: 151 RGECQAEGVLFFQGDREWFWDLATGTM------KERSWPAV-GNCSSALRWL-GRYYCFQ 202
Query: 495 GQEYWKVLDGELEVAPGYPQSTARDWLVC 523
G ++ + EV P YP+ ++ C
Sbjct: 203 GNQFLRFDPVRGEVPPRYPRDVRDYFMPC 231
Score = 33.1 bits (74), Expect = 0.75
Identities = 35/136 (25%), Positives = 54/136 (39%), Gaps = 18/136 (13%)
Query: 331 RCSTHFDAVAQI---RGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDA 387
RCS H A G + F G ++WRL R P H++ P +VDA
Sbjct: 256 RCSPHLVLSALTSDNHGATYAFSGTHYWRLDTSRDGWHSWPI-AHQW----PQGPSAVDA 310
Query: 388 VYERTSDHKIVFFKGDRYWVFKDN---NVEEGYPRPVSDFSLPPGGI-----DAAFSWAH 439
+ + + K+ +G + +VF + GYP+ + P GI DAAF
Sbjct: 311 AF--SWEEKLYLVQGTQVYVFLTKGGYTLVSGYPKRLEKEVGTPHGIILDSVDAAFICPG 368
Query: 440 NDRTYFFKDQLYWRYD 455
+ R + + W D
Sbjct: 369 SSRLHIMAGRRLWWLD 384
>gi|88853069 vitronectin precursor [Homo sapiens]
Length = 478
Score = 66.2 bits (160), Expect = 8e-11
Identities = 78/284 (27%), Positives = 116/284 (40%), Gaps = 43/284 (15%)
Query: 301 SPTAQPEEPPLLPE----PPDNRSSAP----PRKDVP----HRCSTH-FDAVAQIR-GEA 346
+P +PEE PE P+ S P P + P CS FDA ++ G
Sbjct: 113 TPVLKPEEEAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSL 172
Query: 347 FFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTS-DHKIVFFKGDRY 405
F F+G+Y + L ++ + P + W G+ +DA + R + K FKG +Y
Sbjct: 173 FAFRGQYCYELD-EKAVRPGYPKLIRDVW-GIE---GPIDAAFTRINCQGKTYLFKGSQY 227
Query: 406 WVFKDNNVEEGYPRPVSD-FSLPPGGIDAAF-----SWAHNDRTYFFKDQLYWRYDDHTR 459
W F+D ++ YPR +SD F P +DAA S++ +R YFFK + YW Y +
Sbjct: 228 WRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQ 287
Query: 460 HMDPGYPAQSPLWRGVPSTLDD--AMRWSDGASYFFRGQEYWKVLDGELEVAPGYPQSTA 517
P+Q S + + AM D F +W G PQ +
Sbjct: 288 ------PSQEECEGSSLSAVFEHFAMMQRDSWEDIFE-LLFW----GRTSAGTRQPQFIS 336
Query: 518 RDWLVCGDSQADGSVAAGV---DAAEGPRAPPGQHDQSRSEDGY 558
RDW Q D ++A + A P Q + R+ GY
Sbjct: 337 RDWHGV-PGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKGY 379
>gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens]
Length = 358
Score = 55.1 bits (131), Expect = 2e-07
Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 11/93 (11%)
Query: 377 GLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPV-SDFSLPPG--GIDA 433
G +H D+ + RT D F+ ++WV +++ + GYPR V S F P IDA
Sbjct: 261 GGDVHFDNDET---RTKD-----FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDA 312
Query: 434 AFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYP 466
A +T+FF YWRYD++ + +D GYP
Sbjct: 313 AIYEKDTGKTHFFVANEYWRYDENMQSVDAGYP 345
Score = 51.2 bits (121), Expect = 3e-06
Identities = 34/76 (44%), Positives = 42/76 (55%), Gaps = 4/76 (5%)
Query: 163 ALKVWSDIAPLNFHEVAGSAADIQIDFS-KADHNDGYPFDGPGGTVAHAFFPGHHHTAGD 221
A ++WS+ + L F S DI + F AD +D PF G G +AHAF PG GD
Sbjct: 205 AFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPG-PGIGGD 263
Query: 222 THFDDDEAWT--FRSS 235
HFD+DE T FRSS
Sbjct: 264 VHFDNDETRTKDFRSS 279
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.448
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,173,804
Number of Sequences: 37866
Number of extensions: 1775086
Number of successful extensions: 10976
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 87
Number of HSP's successfully gapped in prelim test: 113
Number of HSP's that attempted gapping in prelim test: 9604
Number of HSP's gapped (non-prelim): 1151
length of query: 603
length of database: 18,247,518
effective HSP length: 108
effective length of query: 495
effective length of database: 14,157,990
effective search space: 7008205050
effective search space used: 7008205050
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.