Guide to the Human Genome
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Search of human proteins with 169210281

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169210281 PREDICTED: similar to M-phase phosphoprotein 10
(U3 small nucleolar ribonucleoprotein) [Homo sapiens]
         (213 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169210281 PREDICTED: similar to M-phase phosphoprotein 10 (U3...   439   e-123
gi|169210051 PREDICTED: similar to M-phase phosphoprotein 10 (U3...   439   e-123
gi|169210488 PREDICTED: similar to M-phase phosphoprotein 10 (U3...   435   e-122
gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]                  241   3e-64
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...   140   1e-33
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...   140   1e-33
gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]                  53   2e-07
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa...    50   1e-06
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ...    47   2e-05
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]                45   5e-05
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]                 45   5e-05
gi|13540523 nucleosomal binding protein 1 [Homo sapiens]               45   6e-05
gi|21735415 centromere protein B [Homo sapiens]                        45   6e-05
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa...    44   8e-05
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    44   1e-04
gi|215422388 death-domain associated protein isoform a [Homo sap...    44   1e-04
gi|215422366 death-domain associated protein isoform b [Homo sap...    44   1e-04
gi|4504487 histidine rich calcium binding protein precursor [Hom...    43   2e-04
gi|156104891 general transcription factor IIF, polypeptide 1, 74...    43   2e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    43   2e-04
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo...    43   2e-04
gi|61175239 transcription elongation factor A (SII)-like 5 [Homo...    43   2e-04
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    42   4e-04
gi|87299628 biorientation of chromosomes in cell division 1-like...    42   4e-04
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          42   4e-04
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                42   5e-04
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     42   5e-04
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     42   5e-04
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    42   5e-04
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    42   5e-04

>gi|169210281 PREDICTED: similar to M-phase phosphoprotein 10 (U3
           small nucleolar ribonucleoprotein) [Homo sapiens]
          Length = 213

 Score =  439 bits (1128), Expect = e-123
 Identities = 213/213 (100%), Positives = 213/213 (100%)

Query: 1   MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV 60
           MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV
Sbjct: 1   MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV 60

Query: 61  SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS 120
           SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS
Sbjct: 61  SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS 120

Query: 121 IIDEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHD 180
           IIDEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHD
Sbjct: 121 IIDEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHD 180

Query: 181 DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL 213
           DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL
Sbjct: 181 DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL 213


>gi|169210051 PREDICTED: similar to M-phase phosphoprotein 10 (U3
           small nucleolar ribonucleoprotein) [Homo sapiens]
          Length = 213

 Score =  439 bits (1128), Expect = e-123
 Identities = 213/213 (100%), Positives = 213/213 (100%)

Query: 1   MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV 60
           MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV
Sbjct: 1   MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV 60

Query: 61  SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS 120
           SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS
Sbjct: 61  SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS 120

Query: 121 IIDEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHD 180
           IIDEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHD
Sbjct: 121 IIDEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHD 180

Query: 181 DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL 213
           DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL
Sbjct: 181 DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL 213


>gi|169210488 PREDICTED: similar to M-phase phosphoprotein 10 (U3
           small nucleolar ribonucleoprotein) [Homo sapiens]
          Length = 213

 Score =  435 bits (1119), Expect = e-122
 Identities = 212/213 (99%), Positives = 212/213 (99%)

Query: 1   MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV 60
           MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV
Sbjct: 1   MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV 60

Query: 61  SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS 120
           SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS
Sbjct: 61  SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS 120

Query: 121 IIDEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHD 180
           IIDEKFFQLSEMEAYLENREKEEERKDDNDDES KSSRNVNNKDFFDPVESDEDIASDHD
Sbjct: 121 IIDEKFFQLSEMEAYLENREKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHD 180

Query: 181 DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL 213
           DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL
Sbjct: 181 DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL 213


>gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]
          Length = 681

 Score =  241 bits (616), Expect = 3e-64
 Identities = 131/201 (65%), Positives = 149/201 (74%), Gaps = 27/201 (13%)

Query: 25  VELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRK 84
           + L  ESEEQE EEDGSE E   +EDLEDL EEEEVSDMG D+PE+G++A NSSK +LRK
Sbjct: 104 ISLLPESEEQEREEDGSEIEADDKEDLEDL-EEEEVSDMGNDDPEMGERAENSSKSDLRK 162

Query: 85  SPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEE 144
           SPVFSDEDSDLDFDISKLEQQSKVQN G GKPREKSI+D+KFF+LSEMEAYLEN EKEEE
Sbjct: 163 SPVFSDEDSDLDFDISKLEQQSKVQNKGQGKPREKSIVDDKFFKLSEMEAYLENIEKEEE 222

Query: 145 RKDDNDDE--------------------------SGKSSRNVNNKDFFDPVESDEDIASD 178
           RKDDND+E                          SGKSSRN+  KDFFDPVESDEDI + 
Sbjct: 223 RKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLKYKDFFDPVESDEDITNV 282

Query: 179 HDDELGSNKMMKLLKKKQKKE 199
           HDDEL SNK    + +++ +E
Sbjct: 283 HDDELDSNKEDDEIAEEEAEE 303


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score =  140 bits (352), Expect = 1e-33
 Identities = 79/143 (55%), Positives = 99/143 (69%), Gaps = 9/143 (6%)

Query: 63  MGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSII 122
           MGGDNPEV ++A NSSKF+  KSPV SDEDSDLDF I+KLEQQSKV+N GHGKPREKSI 
Sbjct: 1   MGGDNPEVSERA-NSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIA 59

Query: 123 DEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPV-------ESDEDI 175
           DEKFFQLSEMEAYLENR++   ++ D DD+  +S  +   K+    V       E+ ED 
Sbjct: 60  DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDA 119

Query: 176 ASDHDDELGSNKMMKLLKKKQKK 198
              H  +  S+++    KK+Q+K
Sbjct: 120 GVSHVKK-NSDEVKSSFKKRQEK 141



 Score = 35.8 bits (81), Expect = 0.028
 Identities = 34/137 (24%), Positives = 61/137 (44%), Gaps = 6/137 (4%)

Query: 22  WQIVELGEESEE--QECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-PEVGKKARNSS 78
           W+  E   E EE  Q+ EE   E E   QE+ E +QE+EE      +   E  +K     
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489

Query: 79  KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138
           K   ++  ++  E+     +    EQ+ K+Q       R++  + E+  +L + E   E 
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE---EK 546

Query: 139 REKEEERKDDNDDESGK 155
            +++E R  + ++  GK
Sbjct: 547 MQEQEVRLQELEERLGK 563


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score =  140 bits (352), Expect = 1e-33
 Identities = 79/143 (55%), Positives = 99/143 (69%), Gaps = 9/143 (6%)

Query: 63  MGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSII 122
           MGGDNPEV ++A NSSKF+  KSPV SDEDSDLDF I+KLEQQSKV+N GHGKPREKSI 
Sbjct: 1   MGGDNPEVSERA-NSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIA 59

Query: 123 DEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPV-------ESDEDI 175
           DEKFFQLSEMEAYLENR++   ++ D DD+  +S  +   K+    V       E+ ED 
Sbjct: 60  DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDA 119

Query: 176 ASDHDDELGSNKMMKLLKKKQKK 198
              H  +  S+++    KK+Q+K
Sbjct: 120 GVSHVKK-NSDEVKSSFKKRQEK 141



 Score = 35.8 bits (81), Expect = 0.028
 Identities = 34/137 (24%), Positives = 61/137 (44%), Gaps = 6/137 (4%)

Query: 22  WQIVELGEESEE--QECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-PEVGKKARNSS 78
           W+  E   E EE  Q+ EE   E E   QE+ E +QE+EE      +   E  +K     
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489

Query: 79  KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138
           K   ++  ++  E+     +    EQ+ K+Q       R++  + E+  +L + E   E 
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE---EK 546

Query: 139 REKEEERKDDNDDESGK 155
            +++E R  + ++  GK
Sbjct: 547 MQEQEVRLQELEERLGK 563


>gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]
          Length = 1726

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 53/184 (28%), Positives = 78/184 (42%), Gaps = 18/184 (9%)

Query: 23  QIVELGEESEEQECEEDGSETETGG------QEDLEDLQEEEEVSDMGGDNPEVGKKARN 76
           + VE  ++ EE+E E    + E G        +D ED  EE+E SD G    +VG K R 
Sbjct: 29  KFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRK 88

Query: 77  SSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYL 136
            + F+        D   D DFD+ +     KV+  G    R K + D++     E E   
Sbjct: 89  RTSFD--------DRLEDDDFDLIEENLGVKVKR-GQKYRRVKKMSDDE--DDDEEEYGK 137

Query: 137 ENREKEEERKDDNDDESGKSSRNVNNKDFFDPVESDE-DIASDHDDELGSNKMMKLLKKK 195
           E  EKE   ++   D  G+  +         P E +E D  SD DD +  +    L K K
Sbjct: 138 EEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKKPK 197

Query: 196 QKKE 199
            +K+
Sbjct: 198 WRKK 201



 Score = 35.4 bits (80), Expect = 0.036
 Identities = 40/167 (23%), Positives = 67/167 (40%), Gaps = 24/167 (14%)

Query: 37  EEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLD 96
           +ED  E E G +E  ++   EE   D  G+  +   +A  +   E  +     DE+SD+D
Sbjct: 127 DEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEED----DEESDID 182

Query: 97  FDI--------SKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDD 148
             I         K + + K+        +E   I    F   E E Y E  E+ EE  + 
Sbjct: 183 DFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEY 242

Query: 149 NDDES---------GKSSRNVNNKDFF---DPVESDEDIASDHDDEL 183
            DDE+           + + V+ +  F   +P E +    +D D+E+
Sbjct: 243 EDDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEI 289


>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
           sapiens]
          Length = 1954

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 51/174 (29%), Positives = 86/174 (49%), Gaps = 17/174 (9%)

Query: 31  SEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVFSD 90
           +EE E E++ SE E GG E  +D    E VS      P+  K   N  K + +K    +D
Sbjct: 16  AEEMENEDEMSEEEDGGLEAFDDFFPVEPVSLPKKKKPK--KLKENKCKGKRKKKEGSND 73

Query: 91  EDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDDND 150
           E S+ + D+ + + +S+  +    K ++K + D+K     E +A    R+K++E +DDND
Sbjct: 74  ELSENEEDLEE-KSESEGSDYSPNKKKKKKLKDKK-----EKKA---KRKKKDEDEDDND 124

Query: 151 D---ESGKSSRNVNNKDFFDPVE---SDEDIASDHDDELGSNKMMKLLKKKQKK 198
           D   +  KSS  +  +   D V+   S+ED  +  + +  S  +  L+ KK  K
Sbjct: 125 DGCLKEPKSSGQLMAEWGLDDVDYLFSEEDYHTLTNYKAFSQFLRPLIAKKNPK 178


>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
           sapiens]
          Length = 1150

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 28/101 (27%), Positives = 54/101 (53%), Gaps = 9/101 (8%)

Query: 90  DEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDDN 149
           ++D     D  K +++ +   T   KP+ +   D+K     + +   + R+KE++RKDD+
Sbjct: 801 EKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDK-----DKKEDRDERKKEDKRKDDS 855

Query: 150 DDESGKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMK 190
            D+    +   NN+D +DP+E++E  A D +D+    +M K
Sbjct: 856 KDDD--ETEEDNNQDEYDPMEAEE--AEDEEDDRDEEEMTK 892


>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 48/189 (25%), Positives = 84/189 (44%), Gaps = 29/189 (15%)

Query: 26  ELGEESEEQECEEDGSE--TETGGQEDLEDLQEEEEVSDMGGD--------NPEVGKKAR 75
           E  E+  E+E +ED SE  +E G + + E+   E+++ + G +        + E+ +   
Sbjct: 538 ESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDS 597

Query: 76  NSSKFELRKSP-VFSDEDSDLDFDISKLEQQS------KVQNTGHGKPREKSIIDEKFFQ 128
            +S+FE   S  V  +E S+ +FD    E++       KV +    +  ++   DEK  +
Sbjct: 598 ENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLE 657

Query: 129 LSEMEAYLENR-EKEEERKDDNDDES--GKSSRNVNNKDF---------FDPVESDEDIA 176
            ++ +A   +  EK  E  DD +DE   GK   + + K F         FD  E   +  
Sbjct: 658 AADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKL 717

Query: 177 SDHDDELGS 185
            D  DE G+
Sbjct: 718 FDDSDERGT 726



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 40/166 (24%), Positives = 75/166 (45%), Gaps = 19/166 (11%)

Query: 26  ELGEESEEQECEEDGSETETGGQEDLEDLQE-------EEEVSDMGGDNPEVGKKARNSS 78
           E  +++ + +CEE+G   E+    + E  +E       EE+ S+   D     K++ + S
Sbjct: 502 ESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGS 561

Query: 79  KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138
           + E  ++ +    + DLD + S+ E    V +    K  E++  +   F+    E  L+ 
Sbjct: 562 EREFEENGL----EKDLDEEGSEKELHENVLD----KELEENDSENSEFEDDGSEKVLDE 613

Query: 139 REKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDELG 184
              E E  +D+D++  +   +   K F D  ESDE    ++ DE G
Sbjct: 614 EGSEREFDEDSDEK--EEEEDTYEKVFDD--ESDEKEDEEYADEKG 655



 Score = 32.0 bits (71), Expect = 0.40
 Identities = 36/177 (20%), Positives = 69/177 (38%), Gaps = 16/177 (9%)

Query: 30  ESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-------PEVGKKARNSSKFEL 82
           + ++ E  EDG E E G  E+       E+ ++ G          P+ G +   S K   
Sbjct: 427 DEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESE 486

Query: 83  RKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKE 142
             +PV   E+     +  K   ++  +  G  K  E  +  E     SE E        +
Sbjct: 487 EGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKE-----SEEEV----GPTK 537

Query: 143 EERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKKKQKKE 199
           E  +DD++ ES +      ++D  +    +  +  D D+E    ++ + +  K+ +E
Sbjct: 538 ESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEE 594


>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 48/189 (25%), Positives = 84/189 (44%), Gaps = 29/189 (15%)

Query: 26  ELGEESEEQECEEDGSE--TETGGQEDLEDLQEEEEVSDMGGD--------NPEVGKKAR 75
           E  E+  E+E +ED SE  +E G + + E+   E+++ + G +        + E+ +   
Sbjct: 538 ESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDS 597

Query: 76  NSSKFELRKSP-VFSDEDSDLDFDISKLEQQS------KVQNTGHGKPREKSIIDEKFFQ 128
            +S+FE   S  V  +E S+ +FD    E++       KV +    +  ++   DEK  +
Sbjct: 598 ENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLE 657

Query: 129 LSEMEAYLENR-EKEEERKDDNDDES--GKSSRNVNNKDF---------FDPVESDEDIA 176
            ++ +A   +  EK  E  DD +DE   GK   + + K F         FD  E   +  
Sbjct: 658 AADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKL 717

Query: 177 SDHDDELGS 185
            D  DE G+
Sbjct: 718 FDDSDERGT 726



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 40/166 (24%), Positives = 75/166 (45%), Gaps = 19/166 (11%)

Query: 26  ELGEESEEQECEEDGSETETGGQEDLEDLQE-------EEEVSDMGGDNPEVGKKARNSS 78
           E  +++ + +CEE+G   E+    + E  +E       EE+ S+   D     K++ + S
Sbjct: 502 ESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGS 561

Query: 79  KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138
           + E  ++ +    + DLD + S+ E    V +    K  E++  +   F+    E  L+ 
Sbjct: 562 EREFEENGL----EKDLDEEGSEKELHENVLD----KELEENDSENSEFEDDGSEKVLDE 613

Query: 139 REKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDELG 184
              E E  +D+D++  +   +   K F D  ESDE    ++ DE G
Sbjct: 614 EGSEREFDEDSDEK--EEEEDTYEKVFDD--ESDEKEDEEYADEKG 655



 Score = 32.0 bits (71), Expect = 0.40
 Identities = 36/177 (20%), Positives = 69/177 (38%), Gaps = 16/177 (9%)

Query: 30  ESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-------PEVGKKARNSSKFEL 82
           + ++ E  EDG E E G  E+       E+ ++ G          P+ G +   S K   
Sbjct: 427 DEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESE 486

Query: 83  RKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKE 142
             +PV   E+     +  K   ++  +  G  K  E  +  E     SE E        +
Sbjct: 487 EGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKE-----SEEEV----GPTK 537

Query: 143 EERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKKKQKKE 199
           E  +DD++ ES +      ++D  +    +  +  D D+E    ++ + +  K+ +E
Sbjct: 538 ESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEE 594


>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
          Length = 282

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 40/150 (26%), Positives = 77/150 (51%), Gaps = 13/150 (8%)

Query: 29  EESEEQECEEDGSETE-TGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPV 87
           EE +++E EED +E +   G+ED ++  EE+   D  G+  E G+ A+     +  +   
Sbjct: 126 EEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGN--EKGEDAKEKEDGKKGEDGK 183

Query: 88  FSDEDSDLDFDISKLEQQSKVQNTGHGKPRE--KSIIDEKFFQLSEMEAYLENREKEEER 145
            + ED     +  K E+  K   TG GK  E  K   D+K  +  +++   + +E+E+ +
Sbjct: 184 GNGEDGKEKGEDEKEEEDRK--ETGDGKENEDGKEKGDKK--EGKDVKVKEDEKEREDGK 239

Query: 146 KDD--NDDESGKSSRNVNNKDFFDPVESDE 173
           +D+  N++E+GK   ++  ++  +  E DE
Sbjct: 240 EDEGGNEEEAGKEKEDLKEEE--EGKEEDE 267



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 47/182 (25%), Positives = 78/182 (42%), Gaps = 24/182 (13%)

Query: 23  QIVELGEESEEQECEEDGSETETGGQE---DLEDLQEEEEVSDMGGDNPEVGKKARNSSK 79
           +IVE+ EE+ E   E+ G + E    E   + ED +E+EE  D   +  E GK+ ++   
Sbjct: 96  EIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEE--DQNEEKGEAGKEDKDEKG 153

Query: 80  FELRKSPVFSDEDSDLDFDISKLEQQSKVQN-TGHGKPREKSIIDEKFFQLSEMEAYLEN 138
            E  K     +E  +   D  + E   K ++  G+G+  ++   DEK             
Sbjct: 154 EEDGKEDKNGNEKGE---DAKEKEDGKKGEDGKGNGEDGKEKGEDEK------------E 198

Query: 139 REKEEERKDDNDDESGKSSRN-VNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKKKQK 197
            E  +E  D  ++E GK   +    KD    V+ DE    D  ++ G N+     +K+  
Sbjct: 199 EEDRKETGDGKENEDGKEKGDKKEGKDV--KVKEDEKEREDGKEDEGGNEEEAGKEKEDL 256

Query: 198 KE 199
           KE
Sbjct: 257 KE 258



 Score = 32.0 bits (71), Expect = 0.40
 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 32  EEQECEEDGSETETGGQEDL----EDLQEEEEVSDMGGDNPEVGKKARNSS 78
           E+++  EDG E E G +E+     EDL+EEEE  +      + GKK    S
Sbjct: 230 EDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQS 280



 Score = 31.6 bits (70), Expect = 0.52
 Identities = 35/174 (20%), Positives = 69/174 (39%), Gaps = 4/174 (2%)

Query: 27  LGEESEEQECEEDGSETETGGQEDLEDLQ-EEEEVSDMGGDNPEVGKKARNSSKFELRKS 85
           + E  +E   EED +E    G+  + +    E+E+ ++  +N E   +     K  +   
Sbjct: 63  VAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAE 122

Query: 86  PVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEER 145
               +ED   D +    E+    +     K  E    D+   +  E     E+ +K E+ 
Sbjct: 123 VKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDG 182

Query: 146 KDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKKKQKKE 199
           K + +D   K     + K+  D  E+ +   ++   E G  K  K +K K+ ++
Sbjct: 183 KGNGEDGKEKGE---DEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEK 233


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 42/142 (29%), Positives = 65/142 (45%), Gaps = 25/142 (17%)

Query: 28  GEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPV 87
           GEE EE+E EE+  E E  G+E+ E+ +EEEE    GG+  E+G++          +  V
Sbjct: 405 GEEEEEEEEEEEEEEGE--GEEEEEEGEEEEE---EGGEGEELGEEEEVE-----EEGDV 454

Query: 88  FSDEDSDLDFDISK--LEQQSKVQNT--------GHGKPREKSIIDEKFFQ-----LSEM 132
            SDE+ + D + S   LE +   Q           +G   E       F +      S+ 
Sbjct: 455 DSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDS 514

Query: 133 EAYLENREKEEERKDDNDDESG 154
           E   +  E +E+  DD+D+E G
Sbjct: 515 EEEDDEEEDDEDEDDDDDEEDG 536



 Score = 27.7 bits (60), Expect = 7.6
 Identities = 14/52 (26%), Positives = 26/52 (50%), Gaps = 3/52 (5%)

Query: 131 EMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDE 182
           E E   E   +EEE + + ++E G     +  +   + VE + D+ SD ++E
Sbjct: 413 EEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEE---EEVEEEGDVDSDEEEE 461


>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
           sapiens]
          Length = 1710

 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 40/162 (24%), Positives = 67/162 (41%), Gaps = 22/162 (13%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEE-------EEVSDMGGDNPEVGKKARNSSKFE 81
           ++ + Q     GSE ++   ED +D   E       +E   M G        + + S+ E
Sbjct: 110 QQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEE 169

Query: 82  LRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREK 141
             KS   S ++++ D++     +  K QN    K   K I+ +K  Q+   E      E 
Sbjct: 170 REKS---SCDETESDYEPKNKVKSRKPQNRSKSK-NGKKILGQKKRQIDSSE------ED 219

Query: 142 EEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDEL 183
           ++E   DND  S +    VN        + DE++ +D DD L
Sbjct: 220 DDEEDYDNDKRSSRRQATVNVS-----YKEDEEMKTDSDDLL 256


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 9/154 (5%)

Query: 26  ELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKS 85
           E  EE EE+E EE+   T++  +EDLE +QE +E  D   D  E     ++  K  +   
Sbjct: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQE-DDEEEDEEEEAAAGKDGDKSPMSSL 500

Query: 86  PVFSDEDSDLDFDISKL--EQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEE 143
            + ++++ +    IS+   EQQ+K      G+    S++ E+    S ++A     + EE
Sbjct: 501 QISNEKNLEPGKQISRSSGEQQNK------GRIVSPSLLSEEPLAPSSIDAESNGEQPEE 554

Query: 144 ERKDDNDDESGKSSRNVNNKDFFDPVESDEDIAS 177
              ++    S      +       P   + DI+S
Sbjct: 555 LTLEEESPVSQLFELEIEALPLDTPSSVETDISS 588


>gi|215422388 death-domain associated protein isoform a [Homo
           sapiens]
          Length = 740

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 9/154 (5%)

Query: 26  ELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKS 85
           E  EE EE+E EE+   T++  +EDLE +QE +E  D   D  E     ++  K  +   
Sbjct: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQE-DDEEEDEEEEAAAGKDGDKSPMSSL 500

Query: 86  PVFSDEDSDLDFDISKL--EQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEE 143
            + ++++ +    IS+   EQQ+K      G+    S++ E+    S ++A     + EE
Sbjct: 501 QISNEKNLEPGKQISRSSGEQQNK------GRIVSPSLLSEEPLAPSSIDAESNGEQPEE 554

Query: 144 ERKDDNDDESGKSSRNVNNKDFFDPVESDEDIAS 177
              ++    S      +       P   + DI+S
Sbjct: 555 LTLEEESPVSQLFELEIEALPLDTPSSVETDISS 588


>gi|215422366 death-domain associated protein isoform b [Homo
           sapiens]
          Length = 752

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 9/154 (5%)

Query: 26  ELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKS 85
           E  EE EE+E EE+   T++  +EDLE +QE +E  D   D  E     ++  K  +   
Sbjct: 454 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQE-DDEEEDEEEEAAAGKDGDKSPMSSL 512

Query: 86  PVFSDEDSDLDFDISKL--EQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEE 143
            + ++++ +    IS+   EQQ+K      G+    S++ E+    S ++A     + EE
Sbjct: 513 QISNEKNLEPGKQISRSSGEQQNK------GRIVSPSLLSEEPLAPSSIDAESNGEQPEE 566

Query: 144 ERKDDNDDESGKSSRNVNNKDFFDPVESDEDIAS 177
              ++    S      +       P   + DI+S
Sbjct: 567 LTLEEESPVSQLFELEIEALPLDTPSSVETDISS 600


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 5/123 (4%)

Query: 28  GEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPV 87
           GEE EE+E EE+ + TE G Q         EE  D+   +   G   R+    E      
Sbjct: 192 GEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQG-HEEDDDDD 250

Query: 88  FSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKD 147
             D+D D D D+S   +    ++ GHG   ++ + D    +    +    +R  EE+  D
Sbjct: 251 DDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHR----DPSHRHRSHEEDDND 306

Query: 148 DND 150
           D+D
Sbjct: 307 DDD 309



 Score = 32.0 bits (71), Expect = 0.40
 Identities = 32/157 (20%), Positives = 57/157 (36%), Gaps = 14/157 (8%)

Query: 26  ELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKS 85
           ELG ++          ET  G +  ++++        +  D   + K      K E  + 
Sbjct: 433 ELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEK-EKEED 491

Query: 86  PVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEER 145
           P   +ED +        EQ  K   T HG   ++   DE+     E      N+E+EEE 
Sbjct: 492 PGSHEEDDESS------EQGEK--GTHHGSRDQEDEEDEE-----EGHGLSLNQEEEEEE 538

Query: 146 KDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDE 182
             + ++E     R     +   P+  D     + ++E
Sbjct: 539 DKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEE 575



 Score = 27.7 bits (60), Expect = 7.6
 Identities = 32/141 (22%), Positives = 56/141 (39%), Gaps = 38/141 (26%)

Query: 39  DGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFD 98
           DG + E  G+E+ E+ +EEEE S       E G +A        R     S+ED D+   
Sbjct: 186 DGEDDE--GEEEEEEEEEEEEAST------EYGHQAH-------RHRGHGSEEDEDVS-- 228

Query: 99  ISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSR 158
                         H  P  +    E+           ++ + +++  DD+DD+     R
Sbjct: 229 ----------DGHHHHGPSHRHQGHEE-----------DDDDDDDDDDDDDDDDVSIEYR 267

Query: 159 NVNNKDFFDPVESDEDIASDH 179
           +  ++     +E DED++  H
Sbjct: 268 HQAHRHQGHGIEEDEDVSDGH 288


>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
           [Homo sapiens]
          Length = 517

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 54/200 (27%), Positives = 82/200 (41%), Gaps = 41/200 (20%)

Query: 32  EEQECEEDGSETETGGQE--------DLED-LQEEEEVSDMGGDN----PEVGKKA---- 74
           ++Q+ +ED  E E  G+         DLED L+   + SD  G+     P+  KKA    
Sbjct: 183 KDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAK 242

Query: 75  --RNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSI----------I 122
             R   K +      F D D D DF+  +++  S   ++   +P  K+           +
Sbjct: 243 GGRKKKKKKGSDDEAFEDSD-DGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGV 301

Query: 123 DEKFFQLSEMEAYL---ENREKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDH 179
           DE+     E E      E++E+EEE+K     E  K  R  +++      ESD    SD 
Sbjct: 302 DEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQE--KKRRKDSSE------ESDSSEESDI 353

Query: 180 DDELGSNKMMKLLKKKQKKE 199
           D E  S   M   K   K+E
Sbjct: 354 DSEASSALFMAKKKTPPKRE 373



 Score = 27.7 bits (60), Expect = 7.6
 Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 10/85 (11%)

Query: 136 LENREKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDELG--------SNK 187
           ++ R  +++ +D++++E  K  R   ++     +E D +++SD  D  G        + K
Sbjct: 177 MQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKK 236

Query: 188 MMKLLK--KKQKKEAFLKCEYFETS 210
              L K  +K+KK+     E FE S
Sbjct: 237 KAPLAKGGRKKKKKKGSDDEAFEDS 261


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 39/168 (23%), Positives = 72/168 (42%), Gaps = 10/168 (5%)

Query: 39  DGSETETGGQEDLEDLQEEEEVSDMG--GDNPEVGKKARNSSKFELRKSP----VFSDED 92
           DGSE +   +++ + ++E   ++  G  GD  +   ++R   K   +  P       +ED
Sbjct: 162 DGSEED---EDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNED 218

Query: 93  SDLDFDISKLEQQSKVQNTGHGKPREKSIID-EKFFQLSEMEAYLENREKEEERKDDNDD 151
            D  F I  + Q+   +     K R++      K  +  E+E   +++ K++E +   ++
Sbjct: 219 DDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEE 278

Query: 152 ESGKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKKKQKKE 199
           E+ KS   V+        E  E   +  DD  G  K     KKK +KE
Sbjct: 279 ETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKE 326



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 28/133 (21%), Positives = 57/133 (42%), Gaps = 15/133 (11%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           EE+      E+  +TE  G +D E +  +EE   + G          N    E++++P  
Sbjct: 484 EETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEG----------NKVHIEVKENPEE 533

Query: 89  SDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKD- 147
            +E+ + + +  + E++ + +    G   ++   DEK     +    L+ +  +E   D 
Sbjct: 534 EEEEEEEEEEDEESEEEEEEEGESEGSEGDEE--DEKVSDEKDSGKTLDKKPSKEMSSDS 591

Query: 148 --DNDDESGKSSR 158
             D+DD+  K  R
Sbjct: 592 EYDSDDDRTKEER 604



 Score = 34.7 bits (78), Expect = 0.062
 Identities = 34/150 (22%), Positives = 62/150 (41%), Gaps = 20/150 (13%)

Query: 20  DPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSK 79
           D W+ +   EE+E+ E  +   E +   +E+ E+ +EEEE  +   +  E G+   +   
Sbjct: 504 DDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGD 563

Query: 80  FELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENR 139
            E  K  V  ++DS    D    ++ S          R K           E  AY + +
Sbjct: 564 EEDEK--VSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTK-----------EERAYDKAK 610

Query: 140 EKEEERKDDNDDESGKSSRNVNNKDFFDPV 169
            + E+R+ ++       S+NVN +    P+
Sbjct: 611 RRIEKRRLEH-------SKNVNTEKLRAPI 633



 Score = 33.5 bits (75), Expect = 0.14
 Identities = 40/186 (21%), Positives = 74/186 (39%), Gaps = 27/186 (14%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           E +EE+   +D  +    G++   D  + EE+ D          K   S K    K  ++
Sbjct: 85  ENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELED----------KDSKSKKTAKPKVEMY 134

Query: 89  SDEDSDLDFDISKLEQQSKVQNT------------GHGKPREKSIIDEKFFQLSEMEAYL 136
           S  D D DF+    + + K Q +               K +E+S I+       E + +L
Sbjct: 135 SGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFL 194

Query: 137 ENR---EKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLK 193
           ++R   +K ++ K   + ESG    + + K     V   +    + + +    +  KL K
Sbjct: 195 QSRKGQKKNQKNKPGPNIESGNEDDDASFK--IKTVAQKKAEKKERERKKRDEEKAKLRK 252

Query: 194 KKQKKE 199
            K+K+E
Sbjct: 253 LKEKEE 258



 Score = 32.0 bits (71), Expect = 0.40
 Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 7/67 (10%)

Query: 140 EKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKKKQKKE 199
           E+EEE +++ D+ES +        +  +  E DE ++ + D         K L KK  KE
Sbjct: 534 EEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSG-------KTLDKKPSKE 586

Query: 200 AFLKCEY 206
                EY
Sbjct: 587 MSSDSEY 593



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 25/127 (19%), Positives = 60/127 (47%), Gaps = 18/127 (14%)

Query: 38  EDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDF 97
           E+ +ET T  ++D E  +++++     G+  E  K+ +        K+ V + +++    
Sbjct: 296 EEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPS----KATVKAMQEA---- 347

Query: 98  DISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDDNDDESGKSS 157
            ++KL+++ +         R+K   +E+  +L E+EA  +  E+ E+ K +   +  K  
Sbjct: 348 -LAKLKEEEE---------RQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKER 397

Query: 158 RNVNNKD 164
           +    K+
Sbjct: 398 KERLKKE 404


>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
           [Homo sapiens]
          Length = 666

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 44/152 (28%), Positives = 69/152 (45%), Gaps = 32/152 (21%)

Query: 31  SEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVFSD 90
           SE +  E+  S+ E  G+ED  D  ++E++      N +  ++A+ S + +L+ S    D
Sbjct: 130 SEAEGSEKAHSDDEKWGREDKSDQSDDEKIQ-----NSDDEERAQGSDEDKLQNS----D 180

Query: 91  EDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDDND 150
           +D              K+QNT   +  + S  D++  QLSE E    N + E     DND
Sbjct: 181 DDE-------------KMQNTDDEERPQLS--DDERQQLSEEEK--ANSDDERPVASDND 223

Query: 151 DESGKSSRNVNNKDFFDPVESDEDIASDHDDE 182
           DE        N+ D   P  SDE+   + DDE
Sbjct: 224 DEKQ------NSDDEEQPQLSDEEKMQNSDDE 249



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 40/156 (25%), Positives = 63/156 (40%), Gaps = 16/156 (10%)

Query: 30  ESEEQECEEDGSETET---GGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSP 86
           E+ E+   ED   ++     G E   D ++E   SD G  + E    A  S K       
Sbjct: 89  EASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSE----AEGSEK------- 137

Query: 87  VFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERK 146
             SD++     D S      K+QN+   +  + S  DE   Q S+ +  ++N + EE  +
Sbjct: 138 AHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGS--DEDKLQNSDDDEKMQNTDDEERPQ 195

Query: 147 DDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDE 182
             +D+    S     N D   PV SD D    + D+
Sbjct: 196 LSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDD 231


>gi|61175239 transcription elongation factor A (SII)-like 5 [Homo
           sapiens]
          Length = 206

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 45/184 (24%), Positives = 70/184 (38%), Gaps = 35/184 (19%)

Query: 28  GEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPV 87
           G+   E+  E +G   + G  ED E   +EEE  DM G     GK+              
Sbjct: 10  GKPENERNLESEGKPEDEGSTED-EGKSDEEEKPDMEGKTECEGKR-------------- 54

Query: 88  FSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKD 147
              ED     D  +LE +   +  G  +  +K   + K       +A  E++ +  E++ 
Sbjct: 55  ---EDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGK----PASQAKPESQPRAAEKRP 107

Query: 148 DNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMK----------LLKKKQK 197
             D    K+ R  +      P +S ED+   H   L S +MM+           L+KKQK
Sbjct: 108 AEDYVPRKAKRKTDRGTDDSPKDSQEDLQERH---LSSEEMMRECGDVSRAQEELRKKQK 164

Query: 198 KEAF 201
              F
Sbjct: 165 MGGF 168


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 35/170 (20%), Positives = 75/170 (44%), Gaps = 6/170 (3%)

Query: 26   ELGE-ESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRK 84
            E GE E EE+E E +G + E  G+E+  + + EEE  +  G+  E G+      + E  +
Sbjct: 926  EEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGE--GEGEEEGEGEGEEGEGEGEE 983

Query: 85   SPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEE 144
                 + + +   +  + E + + +  G G+  E+  ++    ++   E   E  E+E E
Sbjct: 984  EEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEG---EVEGEEGEGEGEEEEGE 1040

Query: 145  RKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKK 194
             + +  ++ G+   N  N++  +  E       + ++E    +  K + K
Sbjct: 1041 EEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSK 1090



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 41/167 (24%), Positives = 67/167 (40%), Gaps = 10/167 (5%)

Query: 26  ELGEESEE-QECEEDGSETETGGQEDLEDLQEEEEVSDMG---GDNPEV---GKKARNSS 78
           E G + E  QE EE G E    G+E+  D +EEEE    G   G+  EV    +K     
Sbjct: 716 EQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGER 775

Query: 79  KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138
           K E R       E+     +  + E + + +    G   E   ++E   +  E E   E 
Sbjct: 776 KKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEG 835

Query: 139 REKE---EERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDE 182
            E+E   EE + + ++E G+       ++     E +E      ++E
Sbjct: 836 EEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 40/177 (22%), Positives = 71/177 (40%), Gaps = 36/177 (20%)

Query: 27  LGEESEEQECEEDGS-ETETGGQEDLEDLQEEEEVSDMGG---DNPEVGKKARNSSKFEL 82
           +GE  +  E   DG+ E  + G E  +D + E+   D G    + P  G+K       EL
Sbjct: 644 VGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEK-------EL 696

Query: 83  RKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKE 142
            +   +   D +        EQ+ K +  GH K R + + +    +  E E    +RE+E
Sbjct: 697 AEKEEWKKRDGE--------EQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEE 748

Query: 143 EERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKKKQKKE 199
           EE++ +  +E                    E++  + + E G  K  +   K++K E
Sbjct: 749 EEKEGEGKEEG-----------------EGEEVEGEREKEEGERKKEERAGKEEKGE 788



 Score = 36.6 bits (83), Expect = 0.016
 Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 9/138 (6%)

Query: 25  VELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMG------GDNPEVGKKARNSS 78
           VE G+   E+E EE   E E G  E+ E   EEEE    G      G+  E G++     
Sbjct: 819 VEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEG 878

Query: 79  KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138
           + E  +     +E+ + + +  + E + + +  G G+  E     E+  +  E E   E 
Sbjct: 879 EEEEGEGE--GEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEE 936

Query: 139 REKE-EERKDDNDDESGK 155
            E E E+ + + ++E G+
Sbjct: 937 GEGEGEDGEGEGEEEEGE 954



 Score = 33.1 bits (74), Expect = 0.18
 Identities = 40/195 (20%), Positives = 79/195 (40%), Gaps = 19/195 (9%)

Query: 28   GEESEEQECEEDGSETETGGQEDLEDLQ---EEEEVSDMGGDNPEVGKKARNSSKFELRK 84
            GE  EE E E +  E E  G+E+ E+ +   EEEE    G D    G++     + E  +
Sbjct: 902  GEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEE 961

Query: 85   SPVFSDEDSDLDFDISK------------LEQQSKVQNTGHGKPREKSIIDEKFFQLSEM 132
                 +E+ + + +  +             E++ + +    G+  E+   + +  +  E+
Sbjct: 962  GEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEV 1021

Query: 133  EAYLENREKEEERKDDNDDESG----KSSRNVNNKDFFDPVESDEDIASDHDDELGSNKM 188
            E  +E  E E E +++  +E G    K      N+   +  E +E    +  +E    + 
Sbjct: 1022 EGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQD 1081

Query: 189  MKLLKKKQKKEAFLK 203
             +  KK  K +  +K
Sbjct: 1082 GEEYKKVSKIKGSVK 1096


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 36/173 (20%), Positives = 71/173 (41%), Gaps = 24/173 (13%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEE-VSDMGGDNPEVGKKARNSSKFELRKSPV 87
           E + ++   +  ++T T  +   ED+ ++E+  +D GG+  E   K              
Sbjct: 231 ERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPK-------------- 276

Query: 88  FSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKD 147
            S+E SDL   + +++  +K  N          I+  K  Q    E   ++ +K E++ D
Sbjct: 277 -SEEFSDLPCPVEEIKNYTKEHNN--------LILLNKDVQQESSEQKNKSTDKGEKKPD 327

Query: 148 DNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKKKQKKEA 200
            N+    K  +    +  FD  +  ED     D++    K ++ LK   +K +
Sbjct: 328 SNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNS 380



 Score = 35.4 bits (80), Expect = 0.036
 Identities = 34/162 (20%), Positives = 66/162 (40%), Gaps = 13/162 (8%)

Query: 31   SEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVFSD 90
            S   E +++ S +ET G++  ++  +++ +     D P + K+ R   +    ++ +   
Sbjct: 2833 SRVMEEKDEYSSSETTGEKPEQN--DDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLKMK 2890

Query: 91   EDSDLDFDISKLEQQS-----KVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEER 145
            +DS  D  I  +EQ       KV  T     +E + + E+     + E  +    +   R
Sbjct: 2891 DDSKTDTGIVTVEQSPSSSKLKVMQTDESN-KETANLQERSISNDDGEEKIVTSVRRRGR 2949

Query: 146  KDD-----NDDESGKSSRNVNNKDFFDPVESDEDIASDHDDE 182
            K       +DD           K   DPVE  ++  SD ++E
Sbjct: 2950 KPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEE 2991


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 35/167 (20%), Positives = 66/167 (39%), Gaps = 41/167 (24%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           + S   EC++      + G ED+++ +EE+E  +   DN E G +     + +  +    
Sbjct: 83  DSSSVDECDD------SDGTEDMDE-KEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEI 135

Query: 89  SDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDD 148
            +ED D D D   +E                                 E  E+EEE +++
Sbjct: 136 EEEDEDDDEDGEDVED--------------------------------EEEEEEEEEEEE 163

Query: 149 NDDESGKSSRNVNNKDFFDPVESDEDIASDHD--DELGSNKMMKLLK 193
            ++E+     N +N       E D++   ++D  DEL +  ++ L K
Sbjct: 164 EEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGK 210



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 38/161 (23%), Positives = 72/161 (44%), Gaps = 6/161 (3%)

Query: 26  ELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKS 85
           E G+  EE+E EE+  + +  G ED+ED +EEEE  +   +  E      N     + + 
Sbjct: 125 EEGDREEEEEIEEEDEDDDEDG-EDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQD 183

Query: 86  PVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEER 145
               D ++D   +  +L  +S +     GK  E +    +    SEM +   N  +++  
Sbjct: 184 TEKDDNNNDEYDNYDELVAKSLL---NLGKIAEDAAYRAR--TESEMNSNTSNSLEDDSD 238

Query: 146 KDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDELGSN 186
           K++N     + S ++++    + V+S + +A  H   L  N
Sbjct: 239 KNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSEN 279



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 40/168 (23%), Positives = 70/168 (41%), Gaps = 15/168 (8%)

Query: 29  EESEEQECEEDGSETETGGQEDLED----LQEEEEVSDMGGDNPEVGKKARNSSKFELRK 84
           +E EE E EE   + +  G ED ED     +EEEE+ +   D+ E G+   +  + E  +
Sbjct: 100 DEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEE 159

Query: 85  SPVFSD---EDSDLDFDISKLEQQS-KVQNTGHGKPREKSIIDEKFFQL---SEMEAYLE 137
                +   ED  ++   +++ Q + K  N          ++ +    L   +E  AY  
Sbjct: 160 EEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRA 219

Query: 138 NREKEEERKDDN--DDESGKSSRNVNNKDFFDPVESDEDIASDHDDEL 183
             E E      N  +D+S K + N+  K     ++ D D+  +  D L
Sbjct: 220 RTESEMNSNTSNSLEDDSDK-NENLGRKSELS-LDLDSDVVRETVDSL 265



 Score = 33.1 bits (74), Expect = 0.18
 Identities = 25/107 (23%), Positives = 50/107 (46%), Gaps = 14/107 (13%)

Query: 90  DEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEE--RKD 147
           D D   D D  K E + +  +  + +P ++   DE+            +RE+EEE   +D
Sbjct: 92  DSDGTEDMD-EKEEDEGEEYSEDNDEPGDEDEEDEE-----------GDREEEEEIEEED 139

Query: 148 DNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKK 194
           ++DDE G+   +   ++  +  E +E+   DH     + ++M+  +K
Sbjct: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEK 186


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 39/172 (22%), Positives = 73/172 (42%), Gaps = 14/172 (8%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           +E E QE E++  E E   + + E  + E E  +   +  +  ++ R   +   R     
Sbjct: 298 KEKERQEIEKERRERERERERERERRERERE-REREREREKEKERERERERDRDRDRTKE 356

Query: 89  SDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDD 148
            D D D + D  +  ++S  +N    + REKS   E+             RE+E ER+ +
Sbjct: 357 RDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRER------------ERERERERERE 404

Query: 149 NDDESGKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKKKQKKEA 200
            + E  +       ++     E D+    + D+E  + +  KL +K ++KEA
Sbjct: 405 REREREREREREREREREREREKDKKRDREEDEE-DAYERRKLERKLREKEA 455



 Score = 33.1 bits (74), Expect = 0.18
 Identities = 39/199 (19%), Positives = 80/199 (40%), Gaps = 32/199 (16%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEE-----EEVSDMGGDNPEVGKKARNSSKFELR 83
           E+  E+E E D     T  ++   D + +     E  SD   D     +K+R+  +   R
Sbjct: 338 EKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERER 397

Query: 84  KSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQ-------LSEMEAYL 136
           +     + + + + +  +  ++ + +     K R++   +E  ++       L E EA  
Sbjct: 398 EREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAY 457

Query: 137 ENR---------------EKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDD 181
           + R               EKE ER+++   E  K ++ +  K+F +  + D D   D   
Sbjct: 458 QERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRL--KEFLEDYDDDRD---DPKY 512

Query: 182 ELGSNKMMKLLKKKQKKEA 200
             GS    +L  ++++ EA
Sbjct: 513 YRGSALQKRLRDREKEMEA 531



 Score = 30.8 bits (68), Expect = 0.89
 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 5/97 (5%)

Query: 68  PEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFF 127
           P + K+  N+ + E  K  + S E S       KLE++      G  +   + I  E+  
Sbjct: 257 PLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEK-----GKKEKERQEIEKERRE 311

Query: 128 QLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKD 164
           +  E E   E RE+E ER+ + + E  K       +D
Sbjct: 312 RERERERERERREREREREREREREKEKERERERERD 348



 Score = 28.5 bits (62), Expect = 4.4
 Identities = 29/153 (18%), Positives = 66/153 (43%), Gaps = 22/153 (14%)

Query: 27  LGEESEEQECEEDGSETETGG--QEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRK 84
           L E  E+ + + D  +   G   Q+ L D ++E E  +          + R   + E  +
Sbjct: 496 LKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERD--------RKREKEELEEIR 547

Query: 85  SPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEE 144
             + ++   D D ++ ++EQ+++       + R+  I  E      E E   E ++++EE
Sbjct: 548 QRLLAEGHPDPDAELQRMEQEAE-------RRRQPQIKQE-----PESEEEEEEKQEKEE 595

Query: 145 RKDDNDDESGKSSRNVNNKDFFDPVESDEDIAS 177
           ++++  +E  +  +    K    P+ S   ++S
Sbjct: 596 KREEPMEEEEEPEQKPCLKPTLRPISSAPSVSS 628


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 14/106 (13%)

Query: 28  GEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPV 87
           G E EE+E EE+  E  T  + + E+ +EEEE  + G ++ E    A   S  E+ +  +
Sbjct: 277 GSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE----ASEQSAEEVSEEEM 332

Query: 88  FSDEDSDLD----------FDISKLEQQSKVQNTGHGKPREKSIID 123
             DE+ + +          FD    E +   +  G G P+  ++ +
Sbjct: 333 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 378



 Score = 35.0 bits (79), Expect = 0.047
 Identities = 32/158 (20%), Positives = 67/158 (42%), Gaps = 10/158 (6%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNP----EVGKKARNSSKFELRK 84
           E  +E+E   + S      +ED  D  +    S      P    E+G   +   + ++ +
Sbjct: 188 ERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 247

Query: 85  SPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEE 144
             + SD     D +      +S    +G G   E+   +E+     E  +  E  E+EEE
Sbjct: 248 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE----EEEGSTSEESEEEEE 303

Query: 145 RKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDE 182
            +++ ++E+G +S   + +   +   S+E+++ D + E
Sbjct: 304 EEEEEEEETGSNSEEASEQSAEE--VSEEEMSEDEERE 339



 Score = 29.3 bits (64), Expect = 2.6
 Identities = 18/85 (21%), Positives = 37/85 (43%), Gaps = 1/85 (1%)

Query: 30  ESEEQECEEDGSETETG-GQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           +SE +    + S  E+G G E+ E+ +EEEE      +  E  ++     + E   +   
Sbjct: 259 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 318

Query: 89  SDEDSDLDFDISKLEQQSKVQNTGH 113
           + E S  +    ++ +  + +N  H
Sbjct: 319 ASEQSAEEVSEEEMSEDEERENENH 343


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 14/106 (13%)

Query: 28  GEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPV 87
           G E EE+E EE+  E  T  + + E+ +EEEE  + G ++ E    A   S  E+ +  +
Sbjct: 287 GSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE----ASEQSAEEVSEEEM 342

Query: 88  FSDEDSDLD----------FDISKLEQQSKVQNTGHGKPREKSIID 123
             DE+ + +          FD    E +   +  G G P+  ++ +
Sbjct: 343 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 388



 Score = 35.0 bits (79), Expect = 0.047
 Identities = 32/158 (20%), Positives = 67/158 (42%), Gaps = 10/158 (6%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNP----EVGKKARNSSKFELRK 84
           E  +E+E   + S      +ED  D  +    S      P    E+G   +   + ++ +
Sbjct: 198 ERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 257

Query: 85  SPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEE 144
             + SD     D +      +S    +G G   E+   +E+     E  +  E  E+EEE
Sbjct: 258 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE----EEEGSTSEESEEEEE 313

Query: 145 RKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDE 182
            +++ ++E+G +S   + +   +   S+E+++ D + E
Sbjct: 314 EEEEEEEETGSNSEEASEQSAEE--VSEEEMSEDEERE 349



 Score = 29.3 bits (64), Expect = 2.6
 Identities = 18/85 (21%), Positives = 37/85 (43%), Gaps = 1/85 (1%)

Query: 30  ESEEQECEEDGSETETG-GQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           +SE +    + S  E+G G E+ E+ +EEEE      +  E  ++     + E   +   
Sbjct: 269 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 328

Query: 89  SDEDSDLDFDISKLEQQSKVQNTGH 113
           + E S  +    ++ +  + +N  H
Sbjct: 329 ASEQSAEEVSEEEMSEDEERENENH 353


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 14/106 (13%)

Query: 28  GEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPV 87
           G E EE+E EE+  E  T  + + E+ +EEEE  + G ++ E    A   S  E+ +  +
Sbjct: 278 GSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE----ASEQSAEEVSEEEM 333

Query: 88  FSDEDSDLD----------FDISKLEQQSKVQNTGHGKPREKSIID 123
             DE+ + +          FD    E +   +  G G P+  ++ +
Sbjct: 334 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 379



 Score = 35.0 bits (79), Expect = 0.047
 Identities = 32/158 (20%), Positives = 67/158 (42%), Gaps = 10/158 (6%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNP----EVGKKARNSSKFELRK 84
           E  +E+E   + S      +ED  D  +    S      P    E+G   +   + ++ +
Sbjct: 189 ERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 248

Query: 85  SPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEE 144
             + SD     D +      +S    +G G   E+   +E+     E  +  E  E+EEE
Sbjct: 249 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE----EEEGSTSEESEEEEE 304

Query: 145 RKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDE 182
            +++ ++E+G +S   + +   +   S+E+++ D + E
Sbjct: 305 EEEEEEEETGSNSEEASEQSAEE--VSEEEMSEDEERE 340



 Score = 29.6 bits (65), Expect = 2.0
 Identities = 29/148 (19%), Positives = 59/148 (39%), Gaps = 11/148 (7%)

Query: 30  ESEEQECEEDGSETETG-GQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           +SE +    + S  E+G G E+ E+ +EEEE      +  E  ++     + E   +   
Sbjct: 260 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 319

Query: 89  SDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDD 148
           + E S  +    ++ +  + +N  H       ++ E  F         E+ E EEE  + 
Sbjct: 320 ASEQSAEEVSEEEMSEDEERENENH-----LLVVPESRFDRDSG----ESEEAEEEVGEG 370

Query: 149 NDDESGKSSRN-VNNKDFFDPVESDEDI 175
               S  +  + V +     P+E  +++
Sbjct: 371 TPQSSALTEGDYVPDSPALSPIELKQEL 398


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 14/106 (13%)

Query: 28  GEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPV 87
           G E EE+E EE+  E  T  + + E+ +EEEE  + G ++ E    A   S  E+ +  +
Sbjct: 287 GSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE----ASEQSAEEVSEEEM 342

Query: 88  FSDEDSDLD----------FDISKLEQQSKVQNTGHGKPREKSIID 123
             DE+ + +          FD    E +   +  G G P+  ++ +
Sbjct: 343 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 388



 Score = 35.0 bits (79), Expect = 0.047
 Identities = 32/158 (20%), Positives = 67/158 (42%), Gaps = 10/158 (6%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNP----EVGKKARNSSKFELRK 84
           E  +E+E   + S      +ED  D  +    S      P    E+G   +   + ++ +
Sbjct: 198 ERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 257

Query: 85  SPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEE 144
             + SD     D +      +S    +G G   E+   +E+     E  +  E  E+EEE
Sbjct: 258 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE----EEEGSTSEESEEEEE 313

Query: 145 RKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHDDE 182
            +++ ++E+G +S   + +   +   S+E+++ D + E
Sbjct: 314 EEEEEEEETGSNSEEASEQSAEE--VSEEEMSEDEERE 349



 Score = 29.6 bits (65), Expect = 2.0
 Identities = 29/148 (19%), Positives = 59/148 (39%), Gaps = 11/148 (7%)

Query: 30  ESEEQECEEDGSETETG-GQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           +SE +    + S  E+G G E+ E+ +EEEE      +  E  ++     + E   +   
Sbjct: 269 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 328

Query: 89  SDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDD 148
           + E S  +    ++ +  + +N  H       ++ E  F         E+ E EEE  + 
Sbjct: 329 ASEQSAEEVSEEEMSEDEERENENH-----LLVVPESRFDRDSG----ESEEAEEEVGEG 379

Query: 149 NDDESGKSSRN-VNNKDFFDPVESDEDI 175
               S  +  + V +     P+E  +++
Sbjct: 380 TPQSSALTEGDYVPDSPALSPIELKQEL 407


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.128    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,983,198
Number of Sequences: 37866
Number of extensions: 464180
Number of successful extensions: 6903
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 260
Number of HSP's successfully gapped in prelim test: 404
Number of HSP's that attempted gapping in prelim test: 3083
Number of HSP's gapped (non-prelim): 2578
length of query: 213
length of database: 18,247,518
effective HSP length: 98
effective length of query: 115
effective length of database: 14,536,650
effective search space: 1671714750
effective search space used: 1671714750
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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