Search of human proteins with 169202626

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169202626 PREDICTED: similar to mucin 5, partial [Homo
sapiens]
         (2013 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]   4291   0.0  
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]     2036   0.0  
gi|161019170 mucin 5AC [Homo sapiens]                                2013   0.0  
gi|116284392 mucin 2 precursor [Homo sapiens]                        1516   0.0  
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]            1091   0.0  
gi|151301154 mucin 6, gastric [Homo sapiens]                          955   0.0  
gi|89191868 von Willebrand factor preproprotein [Homo sapiens]        763   0.0  
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ...   754   0.0  
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ...   754   0.0  
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]             612   e-174
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]             612   e-174
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]             612   e-174
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]             612   e-174
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]             612   e-174
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]             612   e-174
gi|134031945 SCO-spondin [Homo sapiens]                               602   e-172
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom...   597   e-170
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom...   597   e-170
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap...   597   e-170
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ...   410   e-114
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]        410   e-114
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr...   360   8e-99
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]            347   9e-95
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr...   315   3e-85
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                       290   1e-77
gi|27881494 zonadhesin isoform 6 [Homo sapiens]                       290   1e-77
gi|239755460 PREDICTED: similar to mucin, partial [Homo sapiens]      277   7e-74
gi|134268640 tectorin alpha precursor [Homo sapiens]                  231   5e-60
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]   189   2e-47
gi|239757284 PREDICTED: similar to Fc fragment of IgG binding pr...   160   1e-38

>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
          Length = 2013

 Score = 4291 bits (11130), Expect = 0.0
 Identities = 2013/2013 (100%), Positives = 2013/2013 (100%)

Query: 1    MSVGRRKLALLWALALALACTRHTGHAQDGSSESSYKHHPALSPIARGPSGVPLRGATVF 60
            MSVGRRKLALLWALALALACTRHTGHAQDGSSESSYKHHPALSPIARGPSGVPLRGATVF
Sbjct: 1    MSVGRRKLALLWALALALACTRHTGHAQDGSSESSYKHHPALSPIARGPSGVPLRGATVF 60

Query: 61   PSLRTIPVVRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNI 120
            PSLRTIPVVRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNI
Sbjct: 61   PSLRTIPVVRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNI 120

Query: 121  QLRRSQESAAPTLSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVE 180
            QLRRSQESAAPTLSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVE
Sbjct: 121  QLRRSQESAAPTLSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVE 180

Query: 181  ARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQK 240
            ARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQK
Sbjct: 181  ARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQK 240

Query: 241  MDDPTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCED 300
            MDDPTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCED
Sbjct: 241  MDDPTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCED 300

Query: 301  TDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEH 360
            TDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEH
Sbjct: 301  TDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEH 360

Query: 361  SRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSG 420
            SRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSG
Sbjct: 361  SRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSG 420

Query: 421  GRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGL 480
            GRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGL
Sbjct: 421  GRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGL 480

Query: 481  TDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTS 540
            TDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTS
Sbjct: 481  TDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTS 540

Query: 541  LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600
            LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF
Sbjct: 541  LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600

Query: 601  KTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFD 660
            KTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFD
Sbjct: 601  KTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFD 660

Query: 661  TCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPT 720
            TCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPT
Sbjct: 661  TCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPT 720

Query: 721  CRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSG 780
            CRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSG
Sbjct: 721  CRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSG 780

Query: 781  AICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCV 840
            AICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCV
Sbjct: 781  AICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCV 840

Query: 841  PGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCL 900
            PGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCL
Sbjct: 841  PGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCL 900

Query: 901  ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTC 960
            ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTC
Sbjct: 901  ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTC 960

Query: 961  SKAIKIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSI 1020
            SKAIKIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSI
Sbjct: 961  SKAIKIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSI 1020

Query: 1021 FINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPKDP 1080
            FINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPKDP
Sbjct: 1021 FINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPKDP 1080

Query: 1081 CTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVA 1140
            CTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVA
Sbjct: 1081 CTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVA 1140

Query: 1141 AYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDV 1200
            AYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDV
Sbjct: 1141 AYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDV 1200

Query: 1201 WGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCL 1260
            WGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCL
Sbjct: 1201 WGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCL 1260

Query: 1261 CTERGVECTYKAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSP 1320
            CTERGVECTYKAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSP
Sbjct: 1261 CTERGVECTYKAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSP 1320

Query: 1321 TTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLP 1380
            TTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLP
Sbjct: 1321 TTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLP 1380

Query: 1381 PVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLR 1440
            PVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLR
Sbjct: 1381 PVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLR 1440

Query: 1441 ALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSSSPAQTTPPTTSKTTE 1500
            ALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSSSPAQTTPPTTSKTTE
Sbjct: 1441 ALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSSSPAQTTPPTTSKTTE 1500

Query: 1501 TRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTPSPPPVPATSTSSMSTTTPGT 1560
            TRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTPSPPPVPATSTSSMSTTTPGT
Sbjct: 1501 TRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTPSPPPVPATSTSSMSTTTPGT 1560

Query: 1561 SVVSSKPTLTEPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPR 1620
            SVVSSKPTLTEPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPR
Sbjct: 1561 SVVSSKPTLTEPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPR 1620

Query: 1621 SVQCRAESFPNTPLADLGQDVICSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRDI 1680
            SVQCRAESFPNTPLADLGQDVICSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRDI
Sbjct: 1621 SVQCRAESFPNTPLADLGQDVICSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRDI 1680

Query: 1681 TRPPKTVATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVT 1740
            TRPPKTVATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVT
Sbjct: 1681 TRPPKTVATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVT 1740

Query: 1741 RNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEV 1800
            RNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEV
Sbjct: 1741 RNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEV 1800

Query: 1801 SIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTP 1860
            SIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTP
Sbjct: 1801 SIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTP 1860

Query: 1861 SGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTT 1920
            SGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTT
Sbjct: 1861 SGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTT 1920

Query: 1921 SASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPT 1980
            SASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPT
Sbjct: 1921 SASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPT 1980

Query: 1981 SSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
            SSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT
Sbjct: 1981 SSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 2036 bits (5275), Expect = 0.0
 Identities = 969/1733 (55%), Positives = 1174/1733 (67%), Gaps = 111/1733 (6%)

Query: 23   HTGHAQDGSSESSYKHHPALSPIARGPSGVPLRGATVFPSLRTIPVVRASNPAHNGRVCS 82
            + GH  DG +       P  SP  R     P+   TVFPSL  +      NPAHNGRVCS
Sbjct: 35   NAGHTMDGGA-------PTSSPTRRVSFVPPV---TVFPSLSPL------NPAHNGRVCS 78

Query: 83   TWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSRVLMKVDG 142
            TWG FHYKTFDGDVFRFPGLCNYVFSEHC AAYEDFN+QLRR    + P ++RV++K  G
Sbjct: 79   TWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRPVVTRVVIKAQG 138

Query: 143  VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELDTK 202
            +V++ + GSVL+NG    LP+S++G+L++QS  Y KV  RL L  +WN +DS LLELD K
Sbjct: 139  LVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGEDSALLELDPK 198

Query: 203  YANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDDPTEQCQDPVPEPPRNCSTG 262
            YAN+TCGLCGDFNG+P  +E  +HN +LTP++FGNLQK+D PTEQC DP+P P  NC+  
Sbjct: 199  YANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKLDGPTEQCPDPLPLPAGNCTDE 258

Query: 263  FGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAG 322
             GIC   L G  F+ C ALVD  +YL AC QDLC C      +C C T  EYSRQC HAG
Sbjct: 259  EGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCP-----TCPCATFVEYSRQCAHAG 313

Query: 323  GLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEG---TV 379
            G P++WR P+ CP+ CP NMQ+ EC SPC DTCSN + ++ CEDHCV GCFCP G   TV
Sbjct: 314  GQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTV 373

Query: 380  LDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPGTCSVLGG 439
            LDDI  +GC+P+ +C C + G  Y+PG +++T C++CTCSGG W CQ++PCPGTCSV GG
Sbjct: 374  LDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQCQDLPCPGTCSVQGG 433

Query: 440  AHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQT 499
            AH ST+D K Y +HGDCSYVL+K C  S+FTVLAELR+CGLTD+E CLK+VTLSLDG  T
Sbjct: 434  AHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDT 493

Query: 500  VVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQL 559
             + ++A G VFLN IYTQLP+SAAN+T+F PS+FFI+ QT LGLQL +QLVP MQ+F++L
Sbjct: 494  AIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRL 553

Query: 560  APKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSL 619
             P  +GQ CGLCGNFN  QADDF  LSGVVEAT AAF NT+K QAAC N RNSFEDPCSL
Sbjct: 554  DPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSL 613

Query: 620  SVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYV 679
            SVENE YA+HWCS+LTD +  F RCH+ + P  ++SNCMFDTCNCERSEDCLCAALSSYV
Sbjct: 614  SVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYV 673

Query: 680  HACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVD 739
            HACAAKGVQL  WRDGVCTK M  CPKS  Y Y V  CQPTCR LSE D+TCSV F+PVD
Sbjct: 674  HACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVD 733

Query: 740  GCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIGGQAPA 799
            GC CP GTFL+D G CV A  CPCY  G+++  GE VHD GA+C+CT GKLSC+G     
Sbjct: 734  GCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQK 793

Query: 800  PV-CAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCI 858
               CAAPMV+ DC N++ G  GA C +SCHTLD+ C+S  CV GCVCP GLV+DG GGCI
Sbjct: 794  STGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCI 853

Query: 859  TAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQS 918
              EDCPCVHNEA+Y+ G+TIRV CNTCTC +R W C+   CL TC  YGDGH++TFDG  
Sbjct: 854  AEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDR 913

Query: 919  YSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHG 978
            YSF G CEY L Q++CG  ++T  +FR+VTEN+PCGTTGTTCSKAIK+F+  +EL L  G
Sbjct: 914  YSFEGSCEYILAQDYCGD-NTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQEG 972

Query: 979  KVEVIGTDESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGN 1038
              + +      + PY IR MGI+LV++T  G+ + WD+KTS+FI L  ++KGRVCGLCGN
Sbjct: 973  TFKAVARGPGGDPPYKIRYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCGN 1031

Query: 1039 FDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSIL 1098
            FDD A+NDFATRSRSVVGD LEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSIL
Sbjct: 1032 FDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSIL 1091

Query: 1099 HGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTP 1158
            HGPTFAAC + V+  +YYEACVNDACACDSGGDCECFCTAVAAYAQACH+ GLCVSWRTP
Sbjct: 1092 HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTP 1151

Query: 1159 SICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFD 1218
              CPLFCD+YNP G CEWHYQPCG PCL+TCRNP G CL D+ GLEGCYPKCPP  P F+
Sbjct: 1152 DTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFN 1211

Query: 1219 EDKMQCVATCPTPPLPPRCH-VHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVC 1277
            ED+M+CVA C        C+   G  Y  GA VP+ +NCQSC CT  G++C +  EAC C
Sbjct: 1212 EDQMKCVAQCG-------CYDKDGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEACTC 1264

Query: 1278 TYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPLV 1337
            TY  + +   DVIY+TTDG G C+ A CG+NGTI R+   C  T    P TF+       
Sbjct: 1265 TYEDRTYSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVACPGTPATTPFTFT------- 1317

Query: 1338 VSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCLWSPWMDVSR 1397
                                +AW   + TSP   + T          E C WS W +  R
Sbjct: 1318 --------------------TAWVPHSTTSPALPVSTVCVR------EVCRWSSWYNGHR 1351

Query: 1398 PGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGLTCR 1457
            P  G   GDF+T ENLR  GY+VC     +ECRA   P +PL  LGQ+V C    GL C 
Sbjct: 1352 PEPGLGGGDFETFENLRQRGYQVCPVLADIECRAAQLPDMPLEELGQQVDCDRMRGLMCA 1411

Query: 1458 NREQASGLCYNYQIRVQCCTPLACSTSSSPAQTTPPTTSKTTETRASGSSAPSSTPGTVS 1517
            N +Q+  LC++Y++RV CC  + C  S +P  +  P+ S +TE                 
Sbjct: 1412 NSQQSPPLCHDYELRVLCCEYVPCGPSPAPGTSPQPSLSASTE----------------- 1454

Query: 1518 LSTARTTPAPGTATSVKKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSC 1577
               A  TP   TAT     + TPS     A ++ + S++ P T   S+      P T++C
Sbjct: 1455 --PAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGPVTVTPSA------PGTTTC 1506

Query: 1578 LQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADL 1637
             Q  C WTEW D  YP     GGD +++  +R  G   C+ P+ ++C+AESFPN  LA +
Sbjct: 1507 -QPRCQWTEWFDEDYPKSEQLGGDVESYDKIRAAGGHLCQQPKDIECQAESFPNWTLAQV 1565

Query: 1638 GQDVICSHTEGLICLNKNQ--LPPICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPH 1695
            GQ V C    GL+C N  Q  +  +CYNY IR+ CC   +     T PP T      T  
Sbjct: 1566 GQKVHCDVHFGLVCRNWEQEGVFKMCYNYRIRVLCCSDDHCRGRATTPPPTTELETATT- 1624

Query: 1696 PTGAQTQTTFTTHMPSAS---TEQPTATSRGGPTAT--------SVTQGTHTT 1737
                 TQ  F+T  P++S   T  P A++   PT +        + T GT TT
Sbjct: 1625 ---TTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTATT 1674



 Score =  306 bits (783), Expect = 2e-82
 Identities = 186/502 (37%), Positives = 263/502 (52%), Gaps = 39/502 (7%)

Query: 1531 TSVKKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTWTEWIDG 1590
            T ++K  + P  P     +T+  + TT      ++ P L  P ++ C++E+C W+ W +G
Sbjct: 1297 TIIRKAVACPGTP-----ATTPFTFTTAWVPHSTTSPAL--PVSTVCVREVCRWSSWYNG 1349

Query: 1591 SYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICSHTEGLI 1650
              P PG+ GGDF+TF+NLR  GY  C     ++CRA   P+ PL +LGQ V C    GL+
Sbjct: 1350 HRPEPGLGGGDFETFENLRQRGYQVCPVLADIECRAAQLPDMPLEELGQQVDCDRMRGLM 1409

Query: 1651 CLNKNQLPPICYNYEIRIQCCETVNVCRDITRP-----PKTVATTRPTPHPTGAQTQTTF 1705
            C N  Q PP+C++YE+R+ CCE V  C     P     P   A+T P   PT  QT  T 
Sbjct: 1410 CANSQQSPPLCHDYELRVLCCEYV-PCGPSPAPGTSPQPSLSASTEPAV-PTPTQTTATE 1467

Query: 1706 TTHMPSASTEQPTA--TSRGGPTATSVTQGTHTTPVTRNCHPRCTWTKWFDVDFPSPGPH 1763
             T +    + + TA  TS+ G ++  VT  T + P T  C PRC WT+WFD D+P     
Sbjct: 1468 KTTLWVTPSIRSTAALTSQTGSSSGPVTV-TPSAPGTTTCQPRCQWTEWFDEDYPKSEQL 1526

Query: 1764 GGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQD 1823
            GGD E+Y+ I  +G  +C++P++I   +C+A+S P  ++  +GQ V C    GLVCRN +
Sbjct: 1527 GGDVESYDKIRAAGGHLCQQPKDI---ECQAESFPNWTLAQVGQKVHCDVHFGLVCRNWE 1583

Query: 1824 QQGPFKMCLNYEVRVLCCETP--RGCPVTSTPV----TAPSTPSGRAISPTQSTSSWQKS 1877
            Q+G FKMC NY +RVLCC     RG   T  P     TA +T +    S  Q TSS   +
Sbjct: 1584 QEGVFKMCYNYRIRVLCCSDDHCRGRATTPPPTTELETATTTTTQALFSTPQPTSSPGLT 1643

Query: 1878 RTTTLVTTST------------TSTPQTSTTYAHTTSTTSA-PTARTTSAPTTRTTSASP 1924
            R     TT+             TST  T+TT   TT   S  PT    +  T  T SA P
Sbjct: 1644 RAPPASTTAVPTLSEGLTSPRYTSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALP 1703

Query: 1925 ASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTT 1984
             +T S     PS  PT +  +  T+      T ST S    +T+ APT ++  + + + T
Sbjct: 1704 GTTGSLGTWRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAET 1763

Query: 1985 SSPQTSTTSAPTTSTTSGPGTT 2006
            S+P+T TT +P T+TT+  GTT
Sbjct: 1764 STPRTETTMSPLTNTTTSQGTT 1785



 Score =  292 bits (748), Expect = 2e-78
 Identities = 228/716 (31%), Positives = 320/716 (44%), Gaps = 120/716 (16%)

Query: 1317 PCSPTTPVPPTT----FSFSTPPLVVSSTHTPSNGPSSAHTGPP---SSAWPTTAGTSPR 1369
            PC P+ P P T+     S ST P V + T T +   ++    P    ++A  +  G+S  
Sbjct: 1434 PCGPS-PAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSG 1492

Query: 1370 TRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVEC 1429
                T SA     C  +C W+ W D   P      GD ++ + +RA G  +C+ P+ +EC
Sbjct: 1493 PVTVTPSAPGTTTCQPRCQWTEWFDEDYPKSEQLGGDVESYDKIRAAGGHLCQQPKDIEC 1552

Query: 1430 RAEDAPGVPLRALGQRVQCSPDVGLTCRNREQAS--GLCYNYQIRVQCCTPLACSTSSSP 1487
            +AE  P   L  +GQ+V C    GL CRN EQ     +CYNY+IRV C     CS     
Sbjct: 1553 QAESFPNWTLAQVGQKVHCDVHFGLVCRNWEQEGVFKMCYNYRIRVLC-----CSDDHCR 1607

Query: 1488 AQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTPSPPPVPA 1547
             + T P                   P T  L TA       T T+ +  FST  P P   
Sbjct: 1608 GRATTP-------------------PPTTELETA-------TTTTTQALFST--PQP--- 1636

Query: 1548 TSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQN 1607
                   T++PG        T   P++++ +  L                          
Sbjct: 1637 -------TSSPGL-------TRAPPASTTAVPTL-------------------------- 1656

Query: 1608 LRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICSHTEGLICLNKNQLPPICYNYEIR 1667
               EG T      ++       P TP       V    T  L    ++ LP    +    
Sbjct: 1657 --SEGLTSPRYTSTLGTATTGGPTTPAGSTEPTVPGVATSTLP--TRSALPGTTGSLG-- 1710

Query: 1668 IQCCETVNVCRDITRPPKTVATTRPTPHPTG--AQTQTTFTTHMPSASTEQPTATSRGGP 1725
                 T    +  T  P T+AT+R  P  T   A  +   T+  P+ ++E  T+ +    
Sbjct: 1711 -----TWRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETST 1765

Query: 1726 TATSVTQG----THTTPVTRNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKIC 1781
              T  T      T T+  T  C P+C WT+WFDVDFP+ G  GGD ET+ NI  +G K+C
Sbjct: 1766 PRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMC 1825

Query: 1782 RRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCC 1841
              P+ I   +CRA+++PEVSI+ +GQV+ CS E GL C+N+DQ G F MC NY VRVLCC
Sbjct: 1826 WAPKSI---ECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCC 1882

Query: 1842 ETPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTT 1901
            +    CP T      P+T S    S T  T+      TTT  TT++T +  T T+   T 
Sbjct: 1883 DDYSHCPST------PATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTS---TL 1933

Query: 1902 STTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPT-TSITSAPTTST- 1959
             T   P   TT+A TT T ++S A+ +S PG   +     ST + PT TS+T  P++S  
Sbjct: 1934 RTAPPPKVLTTTA-TTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLG 1992

Query: 1960 TSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGT--TPSPVPTT 2013
            T+    S T+ PT + ++A  SST  +  TST    T +TT   G+  TPS  P T
Sbjct: 1993 TTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGT 2048



 Score =  241 bits (614), Expect = 7e-63
 Identities = 218/751 (29%), Positives = 317/751 (42%), Gaps = 97/751 (12%)

Query: 1286 PGDVIYHTTDGTGGCISARCGANGTIERRVYPCSP--TTPVPPTTFSFSTPPLVVSSTHT 1343
            PG     T   T    +A  G+  T      P S   T P P    + +T P V SS  T
Sbjct: 1904 PGTTWILTKPTTTATTTASTGSTAT------PTSTLRTAPPPKVLTTTATTPTVTSSKAT 1957

Query: 1344 PSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTD 1403
            PS+ P +A   P   +  TT   +  T +P++S           L + W  +S+    T 
Sbjct: 1958 PSSSPGTATALPALRSTATTPTATSVTPIPSSS-----------LGTTWTRLSQTTTPTA 2006

Query: 1404 SGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQAS 1463
            +    T              P S    A  +    L A       +  V           
Sbjct: 2007 TMSTAT--------------PSSTPETAHTS--TVLTATATTTGATGSVATP----SSTP 2046

Query: 1464 GLCYNYQIRVQCCTPLACSTSSSPAQT-TPPT--TSKTTETRASGSSAPSSTPGTVS--- 1517
            G  +  ++     T    + SSSP    TPP   ++ TT T    +  PSS PGT     
Sbjct: 2047 GTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTAT 2106

Query: 1518 -LSTARTTPAPGTATSVKKTFSTPSPPP--------VPATSTSSMSTTTPGTSVVSSKPT 1568
             L+T  TT A G+  +   +  T   PP        + AT +++  ++TPGT+ +   P 
Sbjct: 2107 VLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIP--PV 2164

Query: 1569 LTEPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAES 1628
            LT  +T+              G+   P +      T             SP +V+     
Sbjct: 2165 LTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPS-----SPHTVRT---- 2215

Query: 1629 FPNTPLADLGQDVICSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPPKTVA 1688
                           S T G++       P    ++ +      T +    ++ P  +  
Sbjct: 2216 ------------AWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSR 2263

Query: 1689 TTRPTPHP-TGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPRC 1747
            TT   P P T     TT T+   + +T   T TS   P+  S T    TT VT  C P+C
Sbjct: 2264 TTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPS--SPTSAPITTVVTMGCEPQC 2321

Query: 1748 TWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQ 1807
             W++W D  +P PGP GGD +TY+NI  +G  +C +P     L+CRA++ P V +  LGQ
Sbjct: 2322 AWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP---LGLECRAQAQPGVPLRELGQ 2378

Query: 1808 VVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISP 1867
            VV+CS + GLVCRN++Q G FKMC NYE+RV CC     CP  STP T     S  A+  
Sbjct: 2379 VVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH-CP--STPAT-----SSTAMPS 2430

Query: 1868 TQSTSSWQKSRTTTLVTT--STTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPA 1925
            +   ++W  +  TT  TT  ST ST   S+T   T   T   T  T + PT  T +AS  
Sbjct: 2431 STPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASST 2490

Query: 1926 STTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPT-TSTTSAPTSS-- 1982
              T+G  +  S   TT T+++   +  S+P T+T      ST + PT TS T+ P+SS  
Sbjct: 2491 QATAGTPHV-STTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLG 2549

Query: 1983 TTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
            TT +  + TT+   T +T+ P +TP  V T+
Sbjct: 2550 TTWTRLSQTTTPTATMSTATPSSTPETVHTS 2580



 Score =  240 bits (613), Expect = 9e-63
 Identities = 225/795 (28%), Positives = 334/795 (42%), Gaps = 97/795 (12%)

Query: 1306 GANGTI-ERRVYPCSPTTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTA 1364
            G  GT+ E+   P +  + + P++   +T    V +T   +   +S+ + P S+   T  
Sbjct: 3078 GTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWI 3137

Query: 1365 GTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRGT---DSGDFDTLENLRAHGYRV- 1420
             T   T   T +A+ P         + W+        T    +G   T  + RA    + 
Sbjct: 3138 LTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLK 3197

Query: 1421 -----CESPRSVECRA--EDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRV 1473
                   +P  +  RA    +PG        R   +     T      +S L   +    
Sbjct: 3198 VLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTA-TSVTAIPSSSLGTAWTRLS 3256

Query: 1474 QCCTPLACSTSSSPAQTTPPT-------TSKTTETRASGSSA-PSSTPGTVSLS------ 1519
            Q  TP A  ++++P+ +TP T       T+ TT TRA+GS A PSSTPGT   +      
Sbjct: 3257 QTTTPTATMSTATPS-STPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTT 3315

Query: 1520 ----TARTTPAPGTA----------TSVKKTFSTPSPPPVPATS--------------TS 1551
                TA  + +PGTA          T+     ST +P  +P T+              T 
Sbjct: 3316 TTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATG 3375

Query: 1552 SMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDE 1611
            SM+T +  T    + P+LT  +T+       T      G+ P P +      T       
Sbjct: 3376 SMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLT---TTATTPAAT 3432

Query: 1612 GYTFCESPRSVQCRAESFPNTPLADLGQDVI-----------CSHTEGLICLNKNQLPPI 1660
              T   S           PNT     G+ +             S T G++       P  
Sbjct: 3433 SSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPST 3492

Query: 1661 CYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHP-TGAQTQTTFTTHMPSASTEQPTA 1719
              ++        T +    ++ P  +  TT   P P T     T  T+   + +T   T 
Sbjct: 3493 VTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTR 3552

Query: 1720 TSRGGPTATSVTQGTHTTPVTRNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEK 1779
            TS   P+  S T    TT VT  C P+C W++W D  +P PGP GGD +TY+NI  +G  
Sbjct: 3553 TSTLLPS--SPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGA 3610

Query: 1780 ICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVL 1839
            +C +P     L+CRA++ P V +  LGQVV+CS + GLVCRN++Q G FKMC NYE+RV 
Sbjct: 3611 VCEQP---LGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVF 3667

Query: 1840 CCETPR--GCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTY 1897
            CC        P TS+  T  STP    I    +T++     T +  T S+T       T 
Sbjct: 3668 CCNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTE 3727

Query: 1898 AHTTSTTSAPTARTTSAPTTRTTSASP-ASTT--------------SGPGNTPSPVPTTS 1942
              TT+T + PT  T +A +T+ T+ +P  STT              S PG   +     S
Sbjct: 3728 PSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRS 3787

Query: 1943 TISAPT-TSITSAPTTST-TSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST--TSAPTTS 1998
            T + PT TS T+ P++S  T+    S T+ PT + ++A  SST  +  TST  T+  TT+
Sbjct: 3788 TATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTT 3847

Query: 1999 TTSGPGTTPSPVPTT 2013
              +G   TPS  P T
Sbjct: 3848 RATGSVATPSSTPGT 3862



 Score =  237 bits (604), Expect = 1e-61
 Identities = 224/774 (28%), Positives = 324/774 (41%), Gaps = 118/774 (15%)

Query: 1286 PGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPLVVSSTHTPS 1345
            PG     T   T   ++   G+  T        +  T   P   + +T P V SS  TP 
Sbjct: 3719 PGTTWILTEPSTTATVTVPTGSTATASS-----TQATAGTPHVSTTATTPTVTSSKATPF 3773

Query: 1346 NGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSG 1405
            + P +A   P   +  TT   +  T +P++S           L + W  +S+    T + 
Sbjct: 3774 SSPGTATALPALRSTATTPTATSFTAIPSSS-----------LGTTWTRLSQTTTPTATM 3822

Query: 1406 DFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASGL 1465
               T              P S    A  +  +   A   R   S              G 
Sbjct: 3823 STAT--------------PSSTPETAHTSTVLTTTATTTRATGS------VATPSSTPGT 3862

Query: 1466 CYNYQIRVQCCTPLACSTSSSP--AQTTPPTTSKTTETRASGSSA-PSSTPGTVS----L 1518
             +  ++     T    + SSSP  A+T P   S TT    SGS+  PSS PGT      L
Sbjct: 3863 AHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVL 3922

Query: 1519 STARTTPAPGTATSVKKTFSTPSPPP--------VPATSTSSMSTTTPGTSVVSSKPTLT 1570
            +T  TT A G+  +   +  T   PP        + AT +++  ++TPGT+ +   P LT
Sbjct: 3923 TTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIP--PVLT 3980

Query: 1571 EPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFP 1630
              +T+              G+   P +      T       G +   SP S      ++ 
Sbjct: 3981 TTATTPAATSSTVTPSSALGTTHTPPVPNTTATT------HGRSL--SPSSPHTVRTAWT 4032

Query: 1631 NTPLADLGQDVICSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPPKTVATT 1690
            +     LG   I   + G              ++        T +    ++ P  +  TT
Sbjct: 4033 SATSGTLGTTHITEPSTGT-------------SHTPAATTGTTQHSTPALSSPHPSSRTT 4079

Query: 1691 RPTPHP-TGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPRCTW 1749
               P P T     TT T+   + +T   T TS   P+  S T    TT VT  C P+C W
Sbjct: 4080 ESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPS--SPTSAPITTVVTTGCEPQCAW 4137

Query: 1750 TKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVV 1809
            ++W D  +P PGP GGD +TY+NI  +G  +C +P     L+CRA++ P V +  LGQVV
Sbjct: 4138 SEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP---LGLECRAQAQPGVPLGELGQVV 4194

Query: 1810 QCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQ 1869
            +CS + GLVCRN++Q G FKMC NYE+RV CC     CP T      P+T S    S T 
Sbjct: 4195 ECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH-CPST------PATSSTAMPSSTP 4247

Query: 1870 STSSWQKSRTTTLVTTSTT-------STPQTSTTYAHTTSTTSAPTA---RTTSAPTTRT 1919
             T+      TTT  TT++T       STP T+      TS  + PTA   + TS+ + RT
Sbjct: 4248 GTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRT 4307

Query: 1920 TSASPASTTSGPGNTP---SPVP-----TTSTISAPTT-------SITSAPTTSTTSAPT 1964
             +  P  T++   +T    +P+P     TT T+   TT       +I  + T  TT   T
Sbjct: 4308 ATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTST 4367

Query: 1965 SSTTSAPTTSTTSAPTSSTTSSPQTS-----TTSAPTTSTTSGPGTTPSPVPTT 2013
              TT A TT  TS+ TS+ +S+P T+      T+A TT+  +GP  TPS  P T
Sbjct: 4368 VLTTKATTTRATSS-TSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGT 4420



 Score =  236 bits (601), Expect = 2e-61
 Identities = 226/778 (29%), Positives = 330/778 (42%), Gaps = 96/778 (12%)

Query: 1312 ERRVYPCS----PTTPVPPTTFSFSTPP--------LVVSSTHTPSNGPSSAHTGPPSSA 1359
            E RV+ C+    P+TP   +T   S+ P        L  ++T T S G ++  +  P + 
Sbjct: 2406 EIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTT 2465

Query: 1360 WPTTA-GTSPRTRLPT----------ASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFD 1408
            W  T   T+    +PT          A+A  P V       +P +  S+    +  G   
Sbjct: 2466 WILTEPSTTATVTVPTGSTATASSTQATAGTPHV--STTATTPTVTSSKATPFSSPGTAT 2523

Query: 1409 TLENLRAHGYRVCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYN 1468
             L  LR+       +  S       + G     L Q    +P   ++           + 
Sbjct: 2524 ALPALRSTA--TTPTATSFTAIPSSSLGTTWTRLSQTT--TPTATMSTATPSSTPETVHT 2579

Query: 1469 YQIRVQCCTPLACSTSSSPAQTTPPT--TSKTTETRASGSSA-PSSTPGT-----VSLST 1520
              +     T    + S +   +TP T  T+K   T  +G +A PSS+PGT     V +ST
Sbjct: 2580 STVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWIST 2639

Query: 1521 ARTTPAPG---TATSVKKTFSTPSPPPVPATS--TSSMSTTTPGTSVVSSKPTLTEPSTS 1575
              T    G   T +S+  T  TP+      T+  T SM+T +  T    + P+LT  +T+
Sbjct: 2640 TTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATT 2699

Query: 1576 SCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLA 1635
                   T      G+ P P +      T         T   S           PNT   
Sbjct: 2700 ITATGSTTNPSSTPGTTPIPPVLT---TTATTPAATSSTVTPSSALGTTHTPPVPNTTAT 2756

Query: 1636 DLGQDVI-----------CSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPP 1684
              G+ +             S T G +       P    ++        T +    ++ P 
Sbjct: 2757 THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPH 2816

Query: 1685 KTVATTRPTPHP-TGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNC 1743
             +  TT   P P T     T  T+   + +T   T TS   P+  S T    TT VT  C
Sbjct: 2817 PSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPS--SPTSAPITTVVTMGC 2874

Query: 1744 HPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIE 1803
             P+C W++W D  +P PGP GGD +TY+NI  +G  +C +P     L+CRA++ P V + 
Sbjct: 2875 EPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP---LGLECRAQAQPGVPLR 2931

Query: 1804 HLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPR--GCPVTSTPVTAPSTPS 1861
             LGQVV+CS + GLVCRN++Q G FKMC NYE+RV CC        P TS+  T  STP 
Sbjct: 2932 ELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPG 2991

Query: 1862 GRAISPTQSTSSWQKSRTTTLVTTST---TSTPQTSTTYAHTTSTTSAPTA---RTTSAP 1915
               I   Q+T++     TTT  T ST   +STP T+      TST + PTA   + TS+ 
Sbjct: 2992 TTWILTEQTTAA-----TTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSS 3046

Query: 1916 TTRTTSASPASTTSGPGNTP---SPVP-----TTSTISAPTT-------SITSAPTTSTT 1960
            + RT +  P  T++   +T    +P+P     TT T+   TT       +I  + T  TT
Sbjct: 3047 SPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETT 3106

Query: 1961 SAPTSSTTSAPTTSTTSAPTSSTTSSPQTS-----TTSAPTTSTTSGPGTTPSPVPTT 2013
               T  TT A TT  TS+  S+ +S+P T+      T+A TT+  +GP  TPS  P T
Sbjct: 3107 HTSTVLTTKATTTRATSS-MSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGT 3163



 Score =  223 bits (567), Expect = 2e-57
 Identities = 227/786 (28%), Positives = 322/786 (40%), Gaps = 133/786 (16%)

Query: 1292 HTTDGTGGCISARCGANGTIERRV------YPCSPTTPVPPTTFSFSTPPLVVSSTHTPS 1345
            H T+ + G         GT +         +P S TT  PP+  + +      +S  T +
Sbjct: 4043 HITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTAT 4102

Query: 1346 NGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSG 1405
              PS   T   S+  P++  ++P T + T        C  +C WS W+D S P  G   G
Sbjct: 4103 ATPSKTRT---STLLPSSPTSAPITTVVTTG------CEPQCAWSEWLDYSYPMPGPSGG 4153

Query: 1406 DFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASG- 1464
            DFDT  N+RA G  VCE P  +ECRA+  PGVPL  LGQ V+CS D GL CRNREQ    
Sbjct: 4154 DFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKF 4213

Query: 1465 -LCYNYQIRVQCC-------TPLACST---SSSPAQT---TPPTTSKTTETRASGSSAPS 1510
             +C+NY+IRV CC       TP   ST   SS+P  T   T  TT+ TT      ++ PS
Sbjct: 4214 KMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPS 4273

Query: 1511 STPGTVSLSTARTTPAPG-TATSVKKTFS----TPSPPPVPATSTSSMSTTTPGTSVVSS 1565
            STPGT       T+PA   TATS K T S    T +  PV  TST++ ST T  T + SS
Sbjct: 4274 STPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPV-LTSTATKSTATSVTPIPSS 4332

Query: 1566 KPTLTEPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCR 1625
                T  +T +  ++  T    +   +P+         T             + ++   R
Sbjct: 4333 ----TLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVL-----------TTKATTTR 4377

Query: 1626 AESFPNTPLADLGQDVICSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPPK 1685
            A S  +TP          S T G                        T  +  ++T    
Sbjct: 4378 ATSSTSTP----------SSTPG------------------------TTWILTELTTAAT 4403

Query: 1686 TVATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCH- 1744
            T A T PT  P+     T   T + + +T   +  S   P++T  T    T P T     
Sbjct: 4404 TTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVT 4463

Query: 1745 -PRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIE 1803
             P  +          +  PH     T   +  S       P   T L     +    +  
Sbjct: 4464 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTAT 4523

Query: 1804 HLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVT---STPVTAPSTP 1860
                +   S        +Q                +   TP   P T   ST +TA +T 
Sbjct: 4524 SFTAIPSSSLGTTWTRLSQTTT---------PTATMSTATPSSTPETVHTSTVLTATATT 4574

Query: 1861 SGRAISPTQSTSSWQKSRTTTLVTTSTT---STP--------------QTSTTYAHTTST 1903
            +G   S    +S+   + TT + TT+TT   +TP               T+TT   TT T
Sbjct: 4575 TGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPT 4634

Query: 1904 TSAPTARTTSAP---------TTRTTS------ASPASTTSGPGNTPSPVPTTSTISAPT 1948
            TS  T   +S P         TT TT+      A+P+S+T   G  PS   T +TI+A T
Sbjct: 4635 TSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITA-T 4693

Query: 1949 TSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTST-TSGPGTTP 2007
             S T+  +T  T+  T   TS  TT   ++  ++++SSP+T+TT    TST T    T+ 
Sbjct: 4694 GSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSF 4753

Query: 2008 SPVPTT 2013
            +P+P++
Sbjct: 4754 TPIPSS 4759



 Score =  216 bits (549), Expect = 2e-55
 Identities = 221/760 (29%), Positives = 309/760 (40%), Gaps = 91/760 (11%)

Query: 1292 HTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPLVVSSTHTPSNGPSSA 1351
            H T+ + G         GT +      S   P   TT S  +P      T TP +  +++
Sbjct: 2786 HITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSP-----GTTTPGHTRATS 2840

Query: 1352 HTGPPSSAWPTTAGTSPRTRLPTASASLPPV------CGEKCLWSPWMDVSRPGRGTDSG 1405
             T    +A  T + T   T LP++  S P        C  +C WS W+D S P  G   G
Sbjct: 2841 RT----TATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGG 2896

Query: 1406 DFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQAS-- 1463
            DFDT  N+RA G  VCE P  +ECRA+  PGVPLR LGQ V+CS D GL CRNREQ    
Sbjct: 2897 DFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKF 2956

Query: 1464 GLCYNYQIRVQCC-------TPLACST---SSSPAQT---TPPTTSKTTETRASGSSAPS 1510
             +C+NY+IRV CC       TP   ST   SS+P  T   T  TT+ TT      ++ PS
Sbjct: 2957 KMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPS 3016

Query: 1511 STPGTVS----LSTARTTPAPGTATSVKKTFS----TPSPPPVPATSTSSMSTTTPGTSV 1562
            STPGT      L++  TTP   TATS K T S    T +  PV  TST++ ST T  T +
Sbjct: 3017 STPGTAPPPKVLTSTATTP---TATSSKATSSSSPRTATTLPV-LTSTATKSTATSFTPI 3072

Query: 1563 VSSKPTLTEPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSV 1622
                P+ T  +T +  ++  T    +   +P+         T             + ++ 
Sbjct: 3073 ----PSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVL-----------TTKAT 3117

Query: 1623 QCRAESFPNTPLADLGQDVICSHTEGLICLNKNQLPPICYNYEIRIQCCET-VNVCRDIT 1681
              RA S  +TP +  G   I +             P    +         T  +    +T
Sbjct: 3118 TTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVT 3177

Query: 1682 RPPKTVATTRPTPHPTGAQTQTTFTTHMPSASTEQPT-ATSRGGPTATSVTQGTHTTPVT 1740
             P  + AT   T    G     T T   P+  + + T ++S G  TA    + T TTP  
Sbjct: 3178 VPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTA 3237

Query: 1741 RNCHP------RCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRA 1794
             +            WT+      P+         +    + +   +             A
Sbjct: 3238 TSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVA 3297

Query: 1795 KSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPV 1854
                     H  + V  +   G         G     L   V +    TP     T TP 
Sbjct: 3298 TPSSTPGTAHTTK-VPTTTTTGFTATPSSSPG---TALTPPVWISTTTTPTTRGSTVTPS 3353

Query: 1855 TAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSA 1914
            + P T     +  T          TTT V T + +TP +S      T T+  P + TT+A
Sbjct: 3354 SIPGTTHTATVLTT----------TTTTVATGSMATPSSS------TQTSGTPPSLTTTA 3397

Query: 1915 PTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTS 1974
             TT T + S  + +S PG T  P+P   T +A T + TS+  T +++  T+ T   P T+
Sbjct: 3398 -TTITATGSTTNPSSTPGTT--PIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTT 3454

Query: 1975 TTSAPTSSTTSSPQTSTTSAPTTSTTSG-PGTTPSPVPTT 2013
             T+   S   SSP T  T+   TS TSG  GTT    P+T
Sbjct: 3455 ATTHGRSLPPSSPHTVRTA--WTSATSGILGTTHITEPST 3492



 Score =  211 bits (537), Expect = 6e-54
 Identities = 228/846 (26%), Positives = 337/846 (39%), Gaps = 166/846 (19%)

Query: 1327 TTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTA-------------GTSPRTRLP 1373
            T  S +T P    ST TPS+ P +AHT    +   TT              GT+  T++P
Sbjct: 3810 TRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVP 3869

Query: 1374 TASAS---LPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECR 1430
            T + +   + P        +P + +S     T SG   T  ++    +       +    
Sbjct: 3870 TTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTV 3929

Query: 1431 AEDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQ-----------IRVQCCTPL 1479
            A  +   P  +   +   +P   +T      A+G   N             +     TP 
Sbjct: 3930 ATGSMATP--SSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPA 3987

Query: 1480 ACSTSSSPAQT-----TPPTTSKTTET-------------RASGSSAPSSTPGTVSLSTA 1521
            A S++ +P+       TPP  + T  T             R + +SA S T GT  ++  
Sbjct: 3988 ATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEP 4047

Query: 1522 RT----TPAPGTATSVKKTFSTPSPPPVPATSTS--SMSTTTPGTSVVSSKPTLTE---- 1571
             T    TPA  T T+   T +  SP P   T+ S  S  TTTPG +  +S+ T T     
Sbjct: 4048 STGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSK 4107

Query: 1572 -------PS-----------TSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGY 1613
                   PS           T+ C +  C W+EW+D SYP PG +GGDFDT+ N+R  G 
Sbjct: 4108 TRTSTLLPSSPTSAPITTVVTTGC-EPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGG 4166

Query: 1614 TFCESPRSVQCRAESFPNTPLADLGQDVICSHTEGLICLNKNQLPP--ICYNYEIRIQCC 1671
              CE P  ++CRA++ P  PL +LGQ V CS   GL+C N+ Q+    +C+NYEIR+ CC
Sbjct: 4167 AVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCC 4226

Query: 1672 E---------------------TVNVCRDITRPPKTVATTRPTPHP-------------T 1697
                                  T  +  ++T    T A+T  T  P             T
Sbjct: 4227 NYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLT 4286

Query: 1698 GAQTQTTFTTHMPSASTEQPTATS-------RGGPTATSVTQGTHTTPVTRNCHPRCTWT 1750
               T  T T+   ++S+   TAT+           TATSVT    +T  T    P  T T
Sbjct: 4287 SPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTT 4346

Query: 1751 KWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQ 1810
                +   +  P    + T+ + + + +    R    T           +  E L     
Sbjct: 4347 PVATMS--TIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTE-LTTAAT 4403

Query: 1811 CSREEGLVCRNQDQQGPFKMCLNYEVRVLCCE------TPRGCPVTSTPVTAPST----- 1859
             +   G         G   +                  TP   P T+  +T PST     
Sbjct: 4404 TTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVT 4463

Query: 1860 -PSGRAI--SPTQSTSSWQKSRTTTLVTTSTTS------TPQTSTTYAHTTSTTSAPTAR 1910
             P+G     S TQ+T+      TT    T T+S      +P T+T      ST + PTA 
Sbjct: 4464 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTAT 4523

Query: 1911 -----------TTSAPTTRTTSASPASTTSGPGNTPSPVPTTS--TISAPTTSITSAPTT 1957
                       TT    ++TT+ +   +T+ P +TP  V T++  T +A TT  T +  T
Sbjct: 4524 SFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVAT 4583

Query: 1958 STTSAPTSSTTSAPTTSTTSAPTSSTTSSPQT--------STTSAPTTST--TSGPGTTP 2007
             +++  T+ TT  PTT+TT   T++ +SSP T        STT+ PTT+T  TSG   TP
Sbjct: 4584 PSSTPGTAHTTKVPTTTTTGF-TATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTP 4642

Query: 2008 SPVPTT 2013
            S +P T
Sbjct: 4643 SSIPGT 4648



 Score =  203 bits (516), Expect = 2e-51
 Identities = 208/701 (29%), Positives = 278/701 (39%), Gaps = 119/701 (16%)

Query: 1326 PTTFSFSTPPLVVSSTH--TP---SNGPSSAHTGPPSSAWPTTAG--------------- 1365
            P+T +  TP    S+T   TP   S  PSS  T  P S   TT G               
Sbjct: 3490 PSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPS 3549

Query: 1366 -TSPRTRLPTASASLPPV------CGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGY 1418
             T   T LP++  S P        C  +C WS W+D S P  G   GDFDT  N+RA G 
Sbjct: 3550 KTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGG 3609

Query: 1419 RVCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASG--LCYNYQIRVQCC 1476
             VCE P  +ECRA+  PGVPLR LGQ V+CS D GL CRNREQ     +C+NY+IRV CC
Sbjct: 3610 AVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCC 3669

Query: 1477 TPLACSTSSSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKT 1536
                C +       TP T+S  T         PSSTPGT  + T  TT    TAT+ + T
Sbjct: 3670 NYGHCPS-------TPATSSTAT---------PSSTPGTTWILTKLTT----TATTTEST 3709

Query: 1537 FSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCL----QELCTWTEWIDGSY 1592
             ST +P   P T+      +T  T  V +  T T  ST +            T  +  S 
Sbjct: 3710 GSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSK 3769

Query: 1593 PAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQ-----DVICSHTE 1647
              P  + G       LR    T           A SF   P + LG          + T 
Sbjct: 3770 ATPFSSPGTATALPALRSTATT---------PTATSFTAIPSSSLGTTWTRLSQTTTPTA 3820

Query: 1648 GLICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQTQTTFTT 1707
             +     +  P   +   +      T      +  P  T  T   T  PT   T TT  T
Sbjct: 3821 TMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPT---TTTTGFT 3877

Query: 1708 HMPSASTEQPTATSRGGPT--ATSVTQGTHTTPVTRNCHPRCTWTKWFDVDFPSPGPHGG 1765
              PS+S      T+R  P   +T+ T  T  + VT +  P  T T        +    G 
Sbjct: 3878 VTPSSS----PGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGS 3933

Query: 1766 DKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQ 1825
                 ++   SG      P  IT            +I   G     S   G         
Sbjct: 3934 MATPSSSTQTSGTP----PSLIT---------TATTITATGSTTNPSSTPGTT------- 3973

Query: 1826 GPFKMCLNYEVRVLCCETPRGCPVTSTPVTA------------PSTPSGRAISPTQS--- 1870
             P        V      TP     T TP +A             +T  GR++SP+     
Sbjct: 3974 -PIP-----PVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTV 4027

Query: 1871 TSSWQKSRTTTLVTTSTTS-TPQTSTTYAHTTSTTSAPT-ARTTSAPTTRTTSASPASTT 1928
             ++W  + + TL TT  T  +  TS T A TT TT   T A ++  P++RTT + P+  T
Sbjct: 4028 RTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGT 4087

Query: 1929 SGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTS 1969
            + PG+T +   TT+T +   T  ++   +S TSAP ++  +
Sbjct: 4088 TTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVT 4128



 Score =  195 bits (495), Expect = 4e-49
 Identities = 215/790 (27%), Positives = 299/790 (37%), Gaps = 113/790 (14%)

Query: 1225 VATCPTPPLP-PRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYNGQR 1283
            + T  TPP+P      HG+S  P +  P          T   +  T+  E          
Sbjct: 2185 LGTTHTPPVPNTMATTHGRSLPPSS--PHTVRTAWTSATSGILGTTHITE---------- 2232

Query: 1284 FHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPLVVSSTHT 1343
              P  V  HT   T G       A  +     +P S TT  PP+  + +      +S  T
Sbjct: 2233 --PSTVTSHTLAATTGTTQHSTPALSS----PHPSSRTTESPPSPGTTTPGHTTATSRTT 2286

Query: 1344 PSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTD 1403
             +  PS   T   S+  P++  ++P T + T        C  +C WS W+D S P  G  
Sbjct: 2287 ATATPSKTRT---STLLPSSPTSAPITTVVTMG------CEPQCAWSEWLDYSYPMPGPS 2337

Query: 1404 SGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQAS 1463
             GDFDT  N+RA G  VCE P  +ECRA+  PGVPLR LGQ V+CS D GL CRNREQ  
Sbjct: 2338 GGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVG 2397

Query: 1464 --GLCYNYQIRVQCCTPLACSTSSSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTA 1521
               +C+NY+IRV CC    C        +TP T+S         ++ PSSTPGT  + T 
Sbjct: 2398 KFKMCFNYEIRVFCCNYGHC-------PSTPATSS---------TAMPSSTPGTTWILTE 2441

Query: 1522 RTTPAPGTATSVKKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCL--- 1578
             TT    TAT+ + T ST +P   P T+      +T  T  V +  T T  ST +     
Sbjct: 2442 LTT----TATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTP 2497

Query: 1579 -QELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADL 1637
                   T  +  S   P  + G       LR    T           A SF   P + L
Sbjct: 2498 HVSTTATTPTVTSSKATPFSSPGTATALPALRSTATT---------PTATSFTAIPSSSL 2548

Query: 1638 GQ-----DVICSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPPKTVATTRP 1692
            G          + T  +     +  P   +   +      T      +  P  T  T   
Sbjct: 2549 GTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHT 2608

Query: 1693 TPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPRCTWTKW 1752
            T   T   T TT  T  PS+S      T+R  P   S T    TTP TR           
Sbjct: 2609 TKVLT---TTTTGFTATPSSS----PGTARTLPVWISTT----TTPTTR----------- 2646

Query: 1753 FDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCS 1812
                        G   T ++I  +           T +   + + P  S +  G     +
Sbjct: 2647 ------------GSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLT 2694

Query: 1813 REEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTS 1872
                 +        P        +  +   T      TS+ VT PS+  G     T  T 
Sbjct: 2695 TTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVT-PSSALG-----TTHTP 2748

Query: 1873 SWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPG 1932
                +  TT   + + S+P T  T    TS TS     T     +  TS +PA+TT   G
Sbjct: 2749 PVPNTTATTHGRSLSPSSPHTVRT--AWTSATSGTLGTTHITEPSTGTSHTPAATT---G 2803

Query: 1933 NTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTT 1992
             T    P  S+    + +  S P+  TT+   +  TS  T + T + T ++T  P + T+
Sbjct: 2804 TTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTS 2863

Query: 1993 SAPTTSTTSG 2002
            +  TT  T G
Sbjct: 2864 APITTVVTMG 2873



 Score =  160 bits (406), Expect = 9e-39
 Identities = 191/676 (28%), Positives = 263/676 (38%), Gaps = 136/676 (20%)

Query: 1317 PCSPTTPVPPTTFSFSTPPLVVSSTH-----TPSNGP---SSAHTGPPSSAWPTTAGT-S 1367
            P  P T  P T  +    P   +ST      T S  P   S   T    ++ P T  T S
Sbjct: 1714 PSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMS 1773

Query: 1368 PRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSV 1427
            P T   T+  +    C  KC W+ W DV  P  G   GD +T EN+RA G ++C +P+S+
Sbjct: 1774 PLTNTTTSQGTTR--CQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSI 1831

Query: 1428 ECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQAS--GLCYNYQIRVQCC--------T 1477
            ECRAE+ P V +  +GQ + CS + GLTC+N +Q     +C+NY +RV CC        T
Sbjct: 1832 ECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPST 1891

Query: 1478 PLACST---SSSPAQT---TPPTTSKTTETRASGSSAPSST----PGTVSLSTARTTP-- 1525
            P   ST   SS+P  T   T PTT+ TT      ++ P+ST    P    L+T  TTP  
Sbjct: 1892 PATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTV 1951

Query: 1526 ---------APGTATSVKKTFSTPSPP------PVPATS-----TSSMSTTTPGTSVVSS 1565
                     +PGTAT++    ST + P      P+P++S     T    TTTP  ++ ++
Sbjct: 1952 TSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTA 2011

Query: 1566 KPTLT-EPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQC 1624
             P+ T E + +S +      T    GS   P    G   T +        F  +P S   
Sbjct: 2012 TPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPG 2071

Query: 1625 RAESFP-----NTPLADLGQDVICSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRD 1679
             A + P      T     G  V  S   G                        T +    
Sbjct: 2072 TALTPPVWISTTTTPTTRGSTVTPSSIPG------------------------TTHTATV 2107

Query: 1680 ITRPPKTVAT-TRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTP 1738
            +T    TVAT +  TP    + TQT+ T   PS +T   T T+ G  T  S T G  TTP
Sbjct: 2108 LTTTTTTVATGSMATP---SSSTQTSGTP--PSLTTTATTITATGSTTNPSSTPG--TTP 2160

Query: 1739 VTRNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHP 1798
            +        T T     +  +P    G   T              P   T      +S P
Sbjct: 2161 IPPVLTTTAT-TPAATSNTVTPSSALGTTHT-------------PPVPNTMATTHGRSLP 2206

Query: 1799 EVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPS 1858
              S  H  +    S   G++       G   +     V         G    STP  +  
Sbjct: 2207 P-SSPHTVRTAWTSATSGIL-------GTTHITEPSTVTSHTLAATTGTTQHSTPALSSP 2258

Query: 1859 TPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTR 1918
             PS R                    TT +  +P T TT  HTT+T+   T  T +   TR
Sbjct: 2259 HPSSR--------------------TTESPPSPGT-TTPGHTTATSR--TTATATPSKTR 2295

Query: 1919 TTSASPASTTSGPGNT 1934
            T++  P+S TS P  T
Sbjct: 2296 TSTLLPSSPTSAPITT 2311



 Score =  113 bits (283), Expect = 2e-24
 Identities = 139/578 (24%), Positives = 215/578 (37%), Gaps = 102/578 (17%)

Query: 747  TFLDDTGKCVQASNCPCYHR--GSMIPNGESVHDSG--------AICT--CTHGKLSCIG 794
            T L  TG      + PC+ R  G     GE +++          A+C   C   +     
Sbjct: 4930 TTLRPTGFPSSHFSTPCFCRAFGQFFSPGEVIYNKTDRAGCHFYAVCNQHCDIDRFQGAC 4989

Query: 795  GQAPAPVCAAPMVFFDCRNATPG-DTGAGCQKSCHTLDM-TCYSPQCVPGCVCPDGLVAD 852
              +P PV +AP+      +  PG D     ++   T  +  C   +CV            
Sbjct: 4990 PTSPPPVSSAPL---SSPSPAPGCDNAIPLRQVNETWTLENCTVARCV------------ 5034

Query: 853  GEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYL 912
            G+   +  +  P V N         I+V   +  CD          C   C+++G  HY 
Sbjct: 5035 GDNRVVLLDPKP-VANVTCVNKHLPIKVSDPSQPCDFHY------ECECICSMWGGSHYS 5087

Query: 913  TFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTT----CSKAIKIFL 968
            TFDG SY+F G+C Y L++       +   +  +  +N  C  + T     C +A+ I  
Sbjct: 5088 TFDGTSYTFRGNCTYVLMRE----IHARFGNLSLYLDNHYCTASATAAAARCPRALSIHY 5143

Query: 969  GGFELKLS----HGKVEVIGTDESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINL 1024
               ++ L+    HGK E +   +   V     + G+ + V   +G   +  +     + +
Sbjct: 5144 KSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSV---LGTTTM--RVDIPALGV 5198

Query: 1025 SPEFKGRVC--------------GLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPS 1070
            S  F G+V               G CG   +   +D   R  +      +   +W +  S
Sbjct: 5199 SVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDS 5258

Query: 1071 ----------CPDALAPKDPCTANPFRKSW-AQKQCSILHGPTFAACHAHVEPARYYEAC 1119
                       P   +P  P ++ P       Q  C ++    FA CH  V P  ++ AC
Sbjct: 5259 RKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNAC 5318

Query: 1120 VNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWR--TPSICPLFCDYYNPEGQCEWH 1177
            ++D C     G  E  C ++ AYA+ C   G+C  WR  T  +C L C    P  +    
Sbjct: 5319 ISDHCR----GRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTC----PPTKV--- 5367

Query: 1178 YQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRC 1237
            Y+PCG     TC N R    +     EGC+  CP +  +F+     CV  CP        
Sbjct: 5368 YKPCGPIQPATC-NSRNQSPQLEGMAEGCF--CPEDQILFNAHMGICVQACPC------V 5418

Query: 1238 HVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEAC 1275
               G    PG    S  NCQSC+C E  V    K   C
Sbjct: 5419 GPDGFPKFPGERWVS--NCQSCVCDEGSVSVQCKPLPC 5454



 Score =  112 bits (281), Expect = 3e-24
 Identities = 182/757 (24%), Positives = 277/757 (36%), Gaps = 114/757 (15%)

Query: 1312 ERRVYPCS----PTTPVPPTTFSFSTPP----LVVSSTHTPSNGPSSAHTGPPSSAWPTT 1363
            E RV+ C+    P+TP   +T   S+ P    ++   T T +   S+  T  PSS    T
Sbjct: 4220 EIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSS----T 4275

Query: 1364 AGTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCES 1423
             GT+P  ++ T+ A+ P     K   S     S P   T      TL  L +       +
Sbjct: 4276 PGTAPPPKVLTSPATTPTATSSKATSS-----SSPRTAT------TLPVLTS------TA 4318

Query: 1424 PRSVECRAEDAPGVPLRALGQRVQ--CSPDVGLTCRNREQASGLCYNYQIRVQCCTPLAC 1481
             +S        P   L   G   +   +P   ++  +        +   +     T    
Sbjct: 4319 TKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRA 4378

Query: 1482 STSSSPAQTTPPTT-------SKTTETRASGSSA-PSSTPGTVSLSTARTTPAPGTATSV 1533
            ++S+S   +TP TT       +  T T A+G +A PSSTPGT  + T  TT    TAT+ 
Sbjct: 4379 TSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTT----TATTT 4434

Query: 1534 KKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQ----ELCTWTEWID 1589
              T ST +P   P T+      +T  T  V +  T T  ST +            T  + 
Sbjct: 4435 ASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVT 4494

Query: 1590 GSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICSHTEGL 1649
             S   P  + G       LR    T           A SF   P + LG           
Sbjct: 4495 SSKATPSSSPGTATALPALRSTATT---------PTATSFTAIPSSSLGTT--------W 4537

Query: 1650 ICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQTQTTFTTHM 1709
              L++   P    +        ETV+    +T    T   T     P+     T  T H 
Sbjct: 4538 TRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSS----TPGTAH- 4592

Query: 1710 PSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPRCTWTKWFDVDFPSPGPHGGDKET 1769
               +T+ PT T+ G     S + GT  TP          W         +     G   T
Sbjct: 4593 ---TTKVPTTTTTGFTATPSSSPGTALTPPV--------WISTTTTPTTTTPTTSGSTVT 4641

Query: 1770 YNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFK 1829
             ++I  +           T +   + + P  S +  G     +     +        P  
Sbjct: 4642 PSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSS 4701

Query: 1830 MCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTT-------TL 1882
                  +  +   T      TS+  T+ S+P      P  ++++ + + T+       TL
Sbjct: 4702 TPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTL 4761

Query: 1883 VTTST----TSTPQTSTTYAHTTST---TSAPTARTTSAPTTRTT-SASPASTTSGPGNT 1934
             TT T    T+TP ++ +  HT+ST   T   T  TT+A  TR T S +  S+T G    
Sbjct: 4762 WTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRI 4821

Query: 1935 PSPVPTTSTISAPTTS---ITSAPTTS--TTSAPTSSTTSAPTTST-TSAPTSSTTSSPQ 1988
             + + TT+T +A T S   ++S P T+   T   T +T   PT ST T++ T  T  +P+
Sbjct: 4822 LTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPK 4881

Query: 1989 TSTT-------------SAPTTSTTSGPGTTPSPVPT 2012
              TT             S+ T  TT  P   PS +PT
Sbjct: 4882 VVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPT 4918



 Score =  110 bits (275), Expect = 1e-23
 Identities = 132/526 (25%), Positives = 195/526 (37%), Gaps = 72/526 (13%)

Query: 430  CPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSET---- 485
            C   CS+ GG+H+STFDG  YT  G+C+YVL +   +    +   L     T S T    
Sbjct: 5074 CECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAA 5133

Query: 486  -CLKSVTL---SLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFI--IAQT 539
             C +++++   S+D V TV ++    E  +  ++ Q+P+S+     F  +   +  +  T
Sbjct: 5134 RCPRALSIHYKSMDIVLTVTMVHGKEEGLI--LFDQIPVSSG----FSKNGVLVSVLGTT 5187

Query: 540  SLGLQ---LNLQLVPTMQLFMQLAPK--LRGQTCGLCGNFNSIQADDFRTLSGVVEATAA 594
            ++ +    L + +    Q+F    P       T G CG   + Q DD     G   A+  
Sbjct: 5188 TMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCK 5247

Query: 595  AFFNTFKTQ----------AACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRC 644
                T+                P   +      S         Q  C  +      F  C
Sbjct: 5248 DMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQ--VFAEC 5305

Query: 645  HAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTC 704
            H  V PG +++ C+ D  +C    +  C +L +Y   C A+GV    WR         TC
Sbjct: 5306 HNLVPPGPFFNACISD--HCRGRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTC 5362

Query: 705  PKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDT--GKCVQASNCP 762
            P +  Y         TC S ++      +     +GC CP+   L +   G CVQA  CP
Sbjct: 5363 PPTKVYKPCGPIQPATCNSRNQSPQLEGM----AEGCFCPEDQILFNAHMGICVQA--CP 5416

Query: 763  CY-HRGSMIPNGESVHDSGAICTCTHGKLSC------IGGQAPAPVCAAPMVFFDCRNAT 815
            C    G     GE    +   C C  G +S          Q   P C  P      R   
Sbjct: 5417 CVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTR--- 5473

Query: 816  PGDTGAGCQKS-CHTLDMTCYSPQCVPGCVCPDG---LVADGEGGCITAEDCP---CVHN 868
            P      C ++ C     TC  PQ +P  VCP G   +    EG C     C    C +N
Sbjct: 5474 PRAENPCCPETVCVCNTTTC--PQSLP--VCPPGQESICTQEEGDCCPTFRCRPQLCSYN 5529

Query: 869  EASYRAGQTI--RVGCNTCTC-----DSRMWRCTDDPCLATCAVYG 907
               Y  G T    + C+ CTC          +C +D C  T    G
Sbjct: 5530 GTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQG 5575



 Score =  110 bits (275), Expect = 1e-23
 Identities = 108/389 (27%), Positives = 156/389 (40%), Gaps = 49/389 (12%)

Query: 80   VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRR-----SQESAAPTLS 134
            +CS WG  HY TFDG  + F G C YV      A + + ++ L       S  +AA    
Sbjct: 5077 ICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAARCP 5136

Query: 135  RVLM---KVDGVVIQLT------KGSVLVNGHPVLLPFSQSGVLIQQSSSYT-KVEA-RL 183
            R L    K   +V+ +T      +G +L +  PV   FS++GVL+    + T +V+   L
Sbjct: 5137 RALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPAL 5196

Query: 184  GLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKM-- 241
            G+ + +N          + + N T G CG          L    T  T     ++ K   
Sbjct: 5197 GVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGT--TAASCKDMAKTWL 5254

Query: 242  --DDPTEQCQDPVPEPPRNCSTG-------------FGICEELLHGQLFSGCVALVDVGS 286
              D   + C  P   PP                     +C+ +L  Q+F+ C  LV  G 
Sbjct: 5255 VPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLML-SQVFAECHNLVPPGP 5313

Query: 287  YLEACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGP--DFCPQKCPNNMQY 344
            +  AC  D C       L   C +L  Y+  C  A G+  DWRG     C   CP    Y
Sbjct: 5314 FFNACISDHC----RGRLEVPCQSLEAYAELC-RARGVCSDWRGATGGLCDLTCPPTKVY 5368

Query: 345  HECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACV-YNGAAY 403
              C      TC+++  S   E     GCFCPE  +L +     C  V  C CV  +G   
Sbjct: 5369 KPCGPIQPATCNSRNQSPQLEG-MAEGCFCPEDQILFNAHMGIC--VQACPCVGPDGFPK 5425

Query: 404  APGATYSTDCTNCTCSGGRWS--CQEVPC 430
             PG  + ++C +C C  G  S  C+ +PC
Sbjct: 5426 FPGERWVSNCQSCVCDEGSVSVQCKPLPC 5454



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 49/164 (29%), Positives = 80/164 (48%), Gaps = 16/164 (9%)

Query: 1850 TSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTA 1909
            TST +T  +T + RA + T + SS     TT ++T  TT+   T+ T +  T +++  T 
Sbjct: 4792 TSTVLTTTATMT-RATNSTATPSS--TLGTTRILTELTTTATTTAATGSTATLSSTPGTT 4848

Query: 1910 RTTSAPTTRTT------SASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAP 1963
               + P+T  T      S + AS+T G  +TP  V T +T+  PT + ++ P++ST    
Sbjct: 4849 WILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATM--PTATASTVPSSSTV--- 4903

Query: 1964 TSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTP 2007
               TT  P    +S PT S ++   +  T+   T   S   +TP
Sbjct: 4904 --GTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSSHFSTP 4945



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 50/170 (29%), Positives = 75/170 (44%), Gaps = 13/170 (7%)

Query: 1849 VTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTT-STPQTSTTYAHTTSTTSAP 1907
            +T+T     +T S    S T  T+      TTT  TT+ T ST   S+T   T   T   
Sbjct: 4796 LTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPS 4855

Query: 1908 TARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSA----- 1962
            T  T   PT  T +AS   +T G  +TP  V T +T+  PT + ++ P++ST        
Sbjct: 4856 TIATVMVPTGSTATAS---STLGTAHTPKVVTTMATM--PTATASTVPSSSTVGTTRTPA 4910

Query: 1963 --PTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPV 2010
              P+S  T + +T ++S  T+   +   +S  S P      G   +P  V
Sbjct: 4911 VLPSSLPTFSVSTVSSSVLTTLRPTGFPSSHFSTPCFCRAFGQFFSPGEV 4960



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 86/358 (24%), Positives = 124/358 (34%), Gaps = 78/358 (21%)

Query: 1293 TTDGTGGCISARCGANGTIERRVYPCSPTTP-------------VPP-----TTFSFSTP 1334
            TT G  G ++      GT      P + TT               PP     TT   +T 
Sbjct: 4573 TTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTT 4632

Query: 1335 PLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCLWSPWMD 1394
            P    ST TPS+ P + HT    +   TT  T     + T S+S         L +    
Sbjct: 4633 PTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGS---MATPSSSTQTSGTPPSLTTTATT 4689

Query: 1395 VSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGL 1454
            ++  G  T+         +         +P +   +A  +   P  A    V  S     
Sbjct: 4690 ITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSS-PRTATTLPVLTSTATKS 4748

Query: 1455 TCRNREQ--ASGLCYNYQIRVQCCTPLACS----TSSSPAQT------------------ 1490
            T  +     +S L   + +  Q  TP++      TSS+P  T                  
Sbjct: 4749 TATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNS 4808

Query: 1491 --TPPTTSKTTE-----------TRASGSSAP-SSTPGTVSLSTARTTPA--------PG 1528
              TP +T  TT            T A+GS+A  SSTPGT  + T  +T A          
Sbjct: 4809 TATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTA 4868

Query: 1529 TATSVKKTFSTPSPPPVPATSTSSMSTTTPGTSVV----------SSKPTLTEPSTSS 1576
            TA+S   T  TP      AT  ++ ++T P +S V          SS PT +  + SS
Sbjct: 4869 TASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSS 4926



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 63/257 (24%), Positives = 100/257 (38%), Gaps = 35/257 (13%)

Query: 1321 TTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLP 1380
            TTP+ P   S +T P   SS  T S+ P +A T P  ++  T +  +  T +P+++    
Sbjct: 4705 TTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSST---- 4760

Query: 1381 PVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLR 1440
                   LW+ W   + P + T      T+  +  H     E+  +       A     R
Sbjct: 4761 -------LWTTW---TVPAQTTTP--MSTMSTI--HTSSTPETTHTSTVLTTTA--TMTR 4804

Query: 1441 ALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSSSPAQT---TPPTTSK 1497
            A       S  +G T    E  +             T    + SS+P  T   T P+T  
Sbjct: 4805 ATNSTATPSSTLGTTRILTELTT------TATTTAATGSTATLSSTPGTTWILTEPSTIA 4858

Query: 1498 TTETRASGSSAPSSTPGTV---SLSTARTTPAPGTATSV--KKTFSTPSPPPVPATSTSS 1552
            T       ++  SST GT     + T   T    TA++V    T  T   P V  +S  +
Sbjct: 4859 TVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPT 4918

Query: 1553 MSTTTPGTSVVSS-KPT 1568
             S +T  +SV+++ +PT
Sbjct: 4919 FSVSTVSSSVLTTLRPT 4935



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 25/70 (35%), Positives = 36/70 (51%), Gaps = 1/70 (1%)

Query: 1265 GVECTYKAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPV 1324
            G   ++ +  C C   GQ F PG+VIY+ TD  G    A C  +  I+R    C PT+P 
Sbjct: 4936 GFPSSHFSTPCFCRAFGQFFSPGEVIYNKTDRAGCHFYAVCNQHCDIDRFQGAC-PTSPP 4994

Query: 1325 PPTTFSFSTP 1334
            P ++   S+P
Sbjct: 4995 PVSSAPLSSP 5004



 Score = 40.0 bits (92), Expect = 0.023
 Identities = 34/120 (28%), Positives = 40/120 (33%), Gaps = 21/120 (17%)

Query: 335  PQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGC---FCPEGTVLDDIGQTG---- 387
            P  C    Q   C  P   T +       C    V  C    CP+   +   GQ      
Sbjct: 5451 PLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQ 5510

Query: 388  ----CVPVSKCA---CVYNGAAYAPGATY--STDCTNCTCSGG-----RWSCQEVPCPGT 433
                C P  +C    C YNG  Y  GAT+  +  C  CTC  G        CQE  C  T
Sbjct: 5511 EEGDCCPTFRCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNT 5570


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 2013 bits (5214), Expect = 0.0
 Identities = 972/1791 (54%), Positives = 1179/1791 (65%), Gaps = 163/1791 (9%)

Query: 23   HTGHAQDGSSESSYKHHPALSPIARGPSGVPLRGATVFPSLRT----------------- 65
            + GH  DG +       P  SP  R     P+   TVFPSL                   
Sbjct: 661  NAGHTMDGGA-------PTSSPTRRVSFVPPV---TVFPSLSRKQMLPLPAGKGVFASPK 710

Query: 66   -------IPVVRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDF 118
                   + +  A NPAHNGRVCSTWG FHYKTFDGDVFRFPGLCNYVFSEHC AAYEDF
Sbjct: 711  GGGPDLGVQLPPALNPAHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDF 770

Query: 119  NIQLRRSQESAAPTLSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTK 178
            N+QLRR    + P ++RV++K  G+V++ + GSVL+NG    LP+S++G+L++QS  Y K
Sbjct: 771  NVQLRRGLVGSRPVVTRVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIK 830

Query: 179  VEARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNL 238
            V  RL L  +WN +DS LLELD KYAN+TCGLCGDFNG+P  +E  +HN +LTP++FGNL
Sbjct: 831  VSIRLVLTFLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNL 890

Query: 239  QKMDDPTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFC 298
            QK+D PTEQC DP+P P  NC+   GIC   L G  F+ C ALVD  +YL AC QDLC C
Sbjct: 891  QKLDGPTEQCPDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRC 950

Query: 299  EDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQ 358
                  +C C T  EYSRQC HAGG P++WR P+ CP+ CP NMQ+ EC SPC DTCSN 
Sbjct: 951  P-----TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNP 1005

Query: 359  EHSRACEDHCVAGCFCPEG---TVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTN 415
            + ++ CEDHCV GCFCP G   TVLDDI  +GC+P+ +C C + G  Y+PG +++T C++
Sbjct: 1006 QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSS 1065

Query: 416  CTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAEL 475
            CTCSGG W CQ++PCPGTCSV GGAH ST+D K Y +HGDCSYVL+K C  S+FTVLAEL
Sbjct: 1066 CTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAEL 1125

Query: 476  RRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFI 535
            R+CGLTD+E CLK+VTLSLDG  T + ++A G VFLN IYTQLP+SAAN+T+F PS+FFI
Sbjct: 1126 RKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFI 1185

Query: 536  IAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAA 595
            + QT LGLQL +QLVP MQ+F++L P  +GQ CGLCGNFN  QADDF  LSGVVEAT AA
Sbjct: 1186 VVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAA 1245

Query: 596  FFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYS 655
            F NT+K QAAC N RNSFEDPCSLSVENE YA+HWCS+LTD +  F RCH+ + P  ++S
Sbjct: 1246 FANTWKAQAACANARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHS 1305

Query: 656  NCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVS 715
            NCMFDTCNCERSEDCLCAALSSYVHACAAKGVQL  WRDGVCTK M  CPKS  Y Y V 
Sbjct: 1306 NCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVD 1365

Query: 716  TCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGES 775
             CQPTCR LSE D+TCSV F+PVDGC CP GTFL+D G CV A  CPCY  G+++  GE 
Sbjct: 1366 ACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEV 1425

Query: 776  VHDSGAICTCTHGKLSCIGGQAPAPV-CAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTC 834
            VHD GA+C+CT GKLSC+G        CAAPMV+ DC N++ G  GA C +SCHTLD+ C
Sbjct: 1426 VHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGC 1485

Query: 835  YSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRC 894
            +S  CV GCVCP GLV+DG GGCI  EDCPCVHNEA+Y+ G+TIRV CNTCTC +R W C
Sbjct: 1486 FSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWEC 1545

Query: 895  TDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCG 954
            +   CL TC  YGDGH++TFDG  YSF G CEY L Q++C G ++T  +FR+VTEN+PCG
Sbjct: 1546 SHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYC-GDNTTHGTFRIVTENIPCG 1604

Query: 955  TTGTTCSKAIKIF----------------------------------LGGFELKLSHGKV 980
            TTGTTCSKAIK+F                                  L  +EL L  G  
Sbjct: 1605 TTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQSYELILQEGTF 1664

Query: 981  EVIGTDESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFD 1040
            + +      + PY IR MGI+LV++T  G+ + WD+KTS+FI L  ++KGRVCGLCGNFD
Sbjct: 1665 KAVARGPGGDPPYKIRYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFD 1723

Query: 1041 DIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHG 1100
            D A+NDFATRSRSVVGD LEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHG
Sbjct: 1724 DNAINDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHG 1783

Query: 1101 PTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSI 1160
            PTFAAC + V+  +YYEACVNDACACDSGGDCECFCTAVAAYAQACH+ GLCVSWRTP  
Sbjct: 1784 PTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDT 1843

Query: 1161 CPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDED 1220
            CPLFCD+YNP G CEWHYQPCG PCL+TCRNP G CL D+ GLEGCYPKCPP  P F+ED
Sbjct: 1844 CPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNED 1903

Query: 1221 KMQCVATCPTPPLPPRCH-VHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTY 1279
            +M+CVA C        C+   G  Y  GA VP+ +NCQSC CT  G++C +  EAC CTY
Sbjct: 1904 QMKCVAQC-------GCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEACTCTY 1956

Query: 1280 NGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPLVVS 1339
              + +   DVIY+TTDG G C+ A CG+NGTI R+   C  T    P TF          
Sbjct: 1957 EDRTYSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVACPGTPATTPFTF---------- 2006

Query: 1340 STHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPG 1399
                             ++AW   + TSP   LP ++  +     E C WS W +  RP 
Sbjct: 2007 -----------------TTAWVPHSTTSP--ALPVSTVCV----REVCRWSSWYNGHRPE 2043

Query: 1400 RGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGLTCRNR 1459
             G   GDF+T ENLR  GY+VC     +ECRA   P +PL  LGQ+V C    GL C N 
Sbjct: 2044 PGLGGGDFETFENLRQRGYQVCPVLADIECRAAQLPDMPLEELGQQVDCDRMRGLMCANS 2103

Query: 1460 EQASGLCYNYQIRVQCCTPLACSTSSSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLS 1519
            +Q+  LC++Y++RV CC  + C  S +P  +  P+ S +TE                   
Sbjct: 2104 QQSPPLCHDYELRVLCCEYVPCGPSPAPGTSPQPSLSASTE------------------- 2144

Query: 1520 TARTTPAPGTATSVKKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQ 1579
             A  TP   TAT     + TPS     A ++ + S++ P T   S+      P T++C Q
Sbjct: 2145 PAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGPVTVTPSA------PGTTTC-Q 2197

Query: 1580 ELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQ 1639
              C WTEW D  YP     GGD +++  +R  G   C+ P+ ++C+AESFPN  LA +GQ
Sbjct: 2198 PRCQWTEWFDEDYPKSEQLGGDVESYDKIRAAGGHLCQQPKDIECQAESFPNWTLAQVGQ 2257

Query: 1640 DVICSHTEGLICLNKNQ--LPPICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPT 1697
             V C    GL+C N  Q  +  +CYNY IR+ CC   +     T PP T      T    
Sbjct: 2258 KVHCDVHFGLVCRNWEQEGVFKMCYNYRIRVLCCSDDHCRGRATTPPPTTELETATT--- 2314

Query: 1698 GAQTQTTFTTHMPSAS---TEQPTATSRGGPTAT--------SVTQGTHTT 1737
               TQ  F+T  P++S   T  P A++   PT +        + T GT TT
Sbjct: 2315 -TTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTATT 2364



 Score = 1305 bits (3377), Expect = 0.0
 Identities = 622/623 (99%), Positives = 622/623 (99%)

Query: 1   MSVGRRKLALLWALALALACTRHTGHAQDGSSESSYKHHPALSPIARGPSGVPLRGATVF 60
           MSVGRRKLALLWALALALACTRHTGHAQDGSSESSYKHHPALSPIARGPSGVPLRGATVF
Sbjct: 1   MSVGRRKLALLWALALALACTRHTGHAQDGSSESSYKHHPALSPIARGPSGVPLRGATVF 60

Query: 61  PSLRTIPVVRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNI 120
           PSLRTIPVVRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNI
Sbjct: 61  PSLRTIPVVRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNI 120

Query: 121 QLRRSQESAAPTLSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVE 180
           QLRRSQESAAPTLSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVE
Sbjct: 121 QLRRSQESAAPTLSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVE 180

Query: 181 ARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQK 240
           ARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQK
Sbjct: 181 ARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQK 240

Query: 241 MDDPTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCED 300
           MDDPTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCED
Sbjct: 241 MDDPTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCED 300

Query: 301 TDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEH 360
           TDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEH
Sbjct: 301 TDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEH 360

Query: 361 SRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSG 420
           SRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSG
Sbjct: 361 SRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSG 420

Query: 421 GRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGL 480
           GRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGL
Sbjct: 421 GRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGL 480

Query: 481 TDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTS 540
           TDSETCLKSVTLSLDG QTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTS
Sbjct: 481 TDSETCLKSVTLSLDGAQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTS 540

Query: 541 LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600
           LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF
Sbjct: 541 LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600

Query: 601 KTQAACPNIRNSFEDPCSLSVEN 623
           KTQAACPNIRNSFEDPCSLSVEN
Sbjct: 601 KTQAACPNIRNSFEDPCSLSVEN 623



 Score =  320 bits (821), Expect = 7e-87
 Identities = 262/828 (31%), Positives = 365/828 (44%), Gaps = 147/828 (17%)

Query: 1317 PCSPTTPVPPTTFSFSTPPLVVSSTH-----TPSNGP---SSAHTGPPSSAWPTTAGT-S 1367
            P  P T  P T  +    P   +ST      T S  P   S   T    ++ P T  T S
Sbjct: 2404 PSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMS 2463

Query: 1368 PRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSV 1427
            P T   T+  +    C  KC W+ W DV  P  G   GD +T EN+RA G ++C +P+S+
Sbjct: 2464 PLTNTTTSQGTTR--CQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSI 2521

Query: 1428 ECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQAS--GLCYNYQIRVQCC--------T 1477
            ECRAE+ P V +  +GQ + CS + GLTC+N +Q     +C+NY +RV CC        T
Sbjct: 2522 ECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPST 2581

Query: 1478 PLACST---SSSPAQT---TPPTTSKTTETRASGSSAPSST----PGTVSLSTARTTP-- 1525
            P   ST   SS+P  T   T PTT+ TT      ++ P+ST    P    L+T  TTP  
Sbjct: 2582 PATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTV 2641

Query: 1526 ---------APGTATSVKKTFSTPSPP------PVPATS--------------TSSMST- 1555
                     +PGTAT++    ST + P      P+P++S              T++MST 
Sbjct: 2642 TSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTA 2701

Query: 1556 --------------------------------TTPGTSVVSSKPTLTEP----STSSCLQ 1579
                                            +TPGT+  +  PT T      + SS   
Sbjct: 2702 TPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPG 2761

Query: 1580 ELCTWTEWID--------GSYPAPGINGGDFDTFQNLRDEGYTFC---------ESPRSV 1622
               T   WI         GS   P    G   T   L     T            +  S 
Sbjct: 2762 TALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSG 2821

Query: 1623 QCRAESFPNTPLADLGQDVI-----------CSHTEGLICLNKNQLPPICYNYEIRIQCC 1671
                   PNT     G+ +             S T G++       P    ++ +     
Sbjct: 2822 TTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTG 2881

Query: 1672 ETVNVCRDITRPPKTVATTRPTPHP-TGAQTQTTFTTHMPSASTEQPTATSRGGPTATSV 1730
             T +    ++ P  +  TT   P P T     TT T+   + +T   T TS   P+  S 
Sbjct: 2882 TTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPS--SP 2939

Query: 1731 TQGTHTTPVTRNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRL 1790
            T    TT VT  C P+C W++W D  +P PGP GGD +TY+NI  +G  +C +P     L
Sbjct: 2940 TSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP---LGL 2996

Query: 1791 QCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVT 1850
            +CRA++ P V +  LGQVV+CS + GLVCRN++Q G FKMC NYE+RV CC     CP  
Sbjct: 2997 ECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH-CP-- 3053

Query: 1851 STPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTT--STTSTPQTSTTYAHTTSTTSAPT 1908
            STP T     S  A+  +   ++W  +  TT  TT  ST ST   S+T   T   T   T
Sbjct: 3054 STPAT-----SSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPST 3108

Query: 1909 ARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTT 1968
              T + PT  T +AS    T+G  +  S   TT T+++   +  S+P T+T      ST 
Sbjct: 3109 TATVTVPTGSTATASSTQATAGTPHV-STTATTPTVTSSKATPFSSPGTATALPALRSTA 3167

Query: 1969 SAPT-TSTTSAPTSS--TTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
            + PT TS T+ P+SS  TT +  + TT+   T +T+ P +TP  V T+
Sbjct: 3168 TTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTS 3215



 Score =  306 bits (783), Expect = 2e-82
 Identities = 186/502 (37%), Positives = 263/502 (52%), Gaps = 39/502 (7%)

Query: 1531 TSVKKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTWTEWIDG 1590
            T ++K  + P  P     +T+  + TT      ++ P L  P ++ C++E+C W+ W +G
Sbjct: 1987 TIIRKAVACPGTP-----ATTPFTFTTAWVPHSTTSPAL--PVSTVCVREVCRWSSWYNG 2039

Query: 1591 SYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICSHTEGLI 1650
              P PG+ GGDF+TF+NLR  GY  C     ++CRA   P+ PL +LGQ V C    GL+
Sbjct: 2040 HRPEPGLGGGDFETFENLRQRGYQVCPVLADIECRAAQLPDMPLEELGQQVDCDRMRGLM 2099

Query: 1651 CLNKNQLPPICYNYEIRIQCCETVNVCRDITRP-----PKTVATTRPTPHPTGAQTQTTF 1705
            C N  Q PP+C++YE+R+ CCE V  C     P     P   A+T P   PT  QT  T 
Sbjct: 2100 CANSQQSPPLCHDYELRVLCCEYV-PCGPSPAPGTSPQPSLSASTEPAV-PTPTQTTATE 2157

Query: 1706 TTHMPSASTEQPTA--TSRGGPTATSVTQGTHTTPVTRNCHPRCTWTKWFDVDFPSPGPH 1763
             T +    + + TA  TS+ G ++  VT  T + P T  C PRC WT+WFD D+P     
Sbjct: 2158 KTTLWVTPSIRSTAALTSQTGSSSGPVTV-TPSAPGTTTCQPRCQWTEWFDEDYPKSEQL 2216

Query: 1764 GGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQD 1823
            GGD E+Y+ I  +G  +C++P++I   +C+A+S P  ++  +GQ V C    GLVCRN +
Sbjct: 2217 GGDVESYDKIRAAGGHLCQQPKDI---ECQAESFPNWTLAQVGQKVHCDVHFGLVCRNWE 2273

Query: 1824 QQGPFKMCLNYEVRVLCCETP--RGCPVTSTPV----TAPSTPSGRAISPTQSTSSWQKS 1877
            Q+G FKMC NY +RVLCC     RG   T  P     TA +T +    S  Q TSS   +
Sbjct: 2274 QEGVFKMCYNYRIRVLCCSDDHCRGRATTPPPTTELETATTTTTQALFSTPQPTSSPGLT 2333

Query: 1878 RTTTLVTTST------------TSTPQTSTTYAHTTSTTSA-PTARTTSAPTTRTTSASP 1924
            R     TT+             TST  T+TT   TT   S  PT    +  T  T SA P
Sbjct: 2334 RAPPASTTAVPTLSEGLTSPRYTSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALP 2393

Query: 1925 ASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTT 1984
             +T S     PS  PT +  +  T+      T ST S    +T+ APT ++  + + + T
Sbjct: 2394 GTTGSLGTWRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAET 2453

Query: 1985 SSPQTSTTSAPTTSTTSGPGTT 2006
            S+P+T TT +P T+TT+  GTT
Sbjct: 2454 STPRTETTMSPLTNTTTSQGTT 2475



 Score =  270 bits (689), Expect = 1e-71
 Identities = 239/838 (28%), Positives = 339/838 (40%), Gaps = 157/838 (18%)

Query: 1317 PCSPTTPVPPTT----FSFSTPPLVVSSTHTPSNGPSSAHTGPP---SSAWPTTAGTSPR 1369
            PC P+ P P T+     S ST P V + T T +   ++    P    ++A  +  G+S  
Sbjct: 2124 PCGPS-PAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSG 2182

Query: 1370 TRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVEC 1429
                T SA     C  +C W+ W D   P      GD ++ + +RA G  +C+ P+ +EC
Sbjct: 2183 PVTVTPSAPGTTTCQPRCQWTEWFDEDYPKSEQLGGDVESYDKIRAAGGHLCQQPKDIEC 2242

Query: 1430 RAEDAPGVPLRALGQRVQCSPDVGLTCRNREQAS--GLCYNYQIRVQCCTPLAC-STSSS 1486
            +AE  P   L  +GQ+V C    GL CRN EQ     +CYNY+IRV CC+   C   +++
Sbjct: 2243 QAESFPNWTLAQVGQKVHCDVHFGLVCRNWEQEGVFKMCYNYRIRVLCCSDDHCRGRATT 2302

Query: 1487 PAQTTPPTTSKTTETRASGSSA-PSSTPG------------------------TVSLSTA 1521
            P  TT   T+ TT T+A  S+  P+S+PG                        T +L TA
Sbjct: 2303 PPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTA 2362

Query: 1522 RT----TPA-------PGTATSVKKTFST------------PSPPPVPATSTSSMSTTTP 1558
             T    TPA       PG ATS   T S             PS PP  A +T + S   P
Sbjct: 2363 TTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARP 2422

Query: 1559 -GTSVVSSK--------PTLTE-----------PSTSSCLQEL---------------CT 1583
             GT+  +SK        PTLT            P T + +  L               C 
Sbjct: 2423 TGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCE 2482

Query: 1584 WTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVIC 1643
            WTEW D  +P  G+ GGD +TF+N+R  G   C +P+S++CRAE++P   +  +GQ + C
Sbjct: 2483 WTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTC 2542

Query: 1644 SHTEGLICLNKNQLP--PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
            S   GL C N++Q     +C+NY +R+ CC+  + C   T    + AT   TP  T   T
Sbjct: 2543 SLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPS-TPATSSTATPSSTPGTTWILT 2601

Query: 1702 Q--TTFTTHMPSASTEQPTATSRGGP-------TATSVT--------------------- 1731
            +  TT TT   + ST  PT+T R  P       TAT+ T                     
Sbjct: 2602 KPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPAL 2661

Query: 1732 QGTHTTPVTRNCHP------RCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPE 1785
            + T TTP   +  P        TWT+      P+         +      +   +     
Sbjct: 2662 RSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATAT 2721

Query: 1786 EITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPR 1845
                    A         H  + V  +   G         G     L   V +    TP 
Sbjct: 2722 TTGATGSVATPSSTPGTAHTTK-VPTTTTTGFTATPSSSPG---TALTPPVWISTTTTPT 2777

Query: 1846 GCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTS 1905
                T TP + P T     +  T          TTT V T + +TP +ST  + TT T  
Sbjct: 2778 TRGSTVTPSSIPGTTHTATVLTT----------TTTTVATGSMATPSSSTQTSGTTHTPP 2827

Query: 1906 APTARTT---------SAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPT 1956
             P    T         S  T RT   S  S   G  +   P   TS   A TT  T   T
Sbjct: 2828 VPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHST 2887

Query: 1957 TSTTSA-PTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
             + +S  P+S TT +P +  T+ P  +T +S  T+T +   T T++   ++P+  P T
Sbjct: 2888 PALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPIT 2945



 Score =  253 bits (645), Expect = 2e-66
 Identities = 282/981 (28%), Positives = 374/981 (38%), Gaps = 245/981 (24%)

Query: 1223 QCVATCPTPPLP-PRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYNG 1281
            Q   T  TPP+P      HG+S  P +  P          T   +  T+  E        
Sbjct: 2818 QTSGTTHTPPVPNTMATTHGRSLPPSS--PHTVRTAWTSATSGILGTTHITE-------- 2867

Query: 1282 QRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPLVVSST 1341
                P  V  HT   T G       A  +     +P S TT  PP+  + +      +S 
Sbjct: 2868 ----PSTVTSHTLAATTGTTQHSTPALSS----PHPSSRTTESPPSPGTTTPGHTTATSR 2919

Query: 1342 HTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRG 1401
             T +  PS   T   S+  P++  ++P T + T        C  +C WS W+D S P  G
Sbjct: 2920 TTATATPSKTRT---STLLPSSPTSAPITTVVTMG------CEPQCAWSEWLDYSYPMPG 2970

Query: 1402 TDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQ 1461
               GDFDT  N+RA G  VCE P  +ECRA+  PGVPLR LGQ V+CS D GL CRNREQ
Sbjct: 2971 PSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQ 3030

Query: 1462 AS--GLCYNYQIRVQCC-------TPLACST---SSSPAQT---TPPTTSKTTETRASGS 1506
                 +C+NY+IRV CC       TP   ST   SS+P  T   T  TT+ TT      +
Sbjct: 3031 VGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGST 3090

Query: 1507 SAPSSTPGTV--------------------------------SLSTARTTP--------- 1525
            + PSSTPGT                                  +ST  TTP         
Sbjct: 3091 ATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATP 3150

Query: 1526 --APGTAT---SVKKTFSTPSPPPVPATSTSSM--------STTTPGTSVVSSKPTLTEP 1572
              +PGTAT   +++ T +TP+     A  +SS+         TTTP  ++ ++ P+ T  
Sbjct: 3151 FSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE 3210

Query: 1573 S--TSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFP 1630
            +  TS+ L    T T    GS   P    G   T + L      F  +P S    A + P
Sbjct: 3211 TVHTSTVLTTTAT-TTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLP 3269

Query: 1631 -----NTPLADLGQDVICSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPPK 1685
                  T     G  V  S   G               +   +    T  V       P 
Sbjct: 3270 VWISTTTTPTTRGSTVTPSSIPGT-------------THTPTVLTTTTTTVATGSMATPS 3316

Query: 1686 TVATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGT----------- 1734
            +   T  T H T     TT TTH  S S   P        +ATS T GT           
Sbjct: 3317 SSTQTSGTTH-TPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS 3375

Query: 1735 -----------HTTPVTRNCHPRCTWTKWFDVDFPSPG--PHGGDKETYNNIIRSGEKIC 1781
                       H+TP   + HP    T+      PSPG    G  + T      +     
Sbjct: 3376 HTPAATTGTTQHSTPALSSPHPSSRTTE----SPPSPGTTTPGHTRATSRTTATATPSKT 3431

Query: 1782 RRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREE-------------------------- 1815
            R     T L     S P  ++  +G   QC+  E                          
Sbjct: 3432 RTS---TLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAG 3488

Query: 1816 --------GLVCRNQ---------------------------DQQGPFKMCLNYEVRVLC 1840
                    GL CR Q                           +Q G FKMC NYE+RV C
Sbjct: 3489 GAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFC 3548

Query: 1841 CETPR--GCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTST---TSTPQTST 1895
            C        P TS+  T  STP    I   Q+T++     TTT  T ST   +STP T+ 
Sbjct: 3549 CNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAA-----TTTATTGSTAIPSSTPGTAP 3603

Query: 1896 TYAHTTSTTSAPTA---RTTSAPTTRTTSASPASTTSGPGNTP---SPVP-----TTSTI 1944
                 TST + PTA   + TS+ + RT +  P  T++   +T    +P+P     TT T+
Sbjct: 3604 PPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTL 3663

Query: 1945 SAPTT-------SITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTS-----TT 1992
               TT       +I  + T  TT   T  TT A TT  TS+  S+ +S+P T+      T
Sbjct: 3664 PEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSS-MSTPSSTPGTTWILTELT 3722

Query: 1993 SAPTTSTTSGPGTTPSPVPTT 2013
            +A TT+  +GP  TPS  P T
Sbjct: 3723 TAATTTAATGPTATPSSTPGT 3743



 Score =  243 bits (621), Expect = 1e-63
 Identities = 224/751 (29%), Positives = 328/751 (43%), Gaps = 64/751 (8%)

Query: 1306 GANGTI-ERRVYPCSPTTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTA 1364
            G  GT+ E+   P +  + + P++   +T    V +T   +   +S+ + P S+   T  
Sbjct: 3658 GTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWI 3717

Query: 1365 GTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRGT---DSGDFDTLENLRAHGYRV- 1420
             T   T   T +A+ P         + W+        T    +G   T  + RA    + 
Sbjct: 3718 LTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLK 3777

Query: 1421 -----CESPRSVECRA--EDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRV 1473
                   +P  +  RA    +PG        R   +     T      +S L   +    
Sbjct: 3778 VLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTA-TSVTAIPSSSLGTAWTRLS 3836

Query: 1474 QCCTPLACSTSSSPAQTTPPT-------TSKTTETRASGSSA-PSSTPGTVSLSTARTTP 1525
            Q  TP A  ++++P+ +TP T       T+ TT TRA+GS A PSSTPGT     A TT 
Sbjct: 3837 QTTTPTATMSTATPS-STPETVHTSTVLTTTTTTTRATGSVATPSSTPGT-----AHTTK 3890

Query: 1526 APGTATSVKKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTWT 1585
             P T T+   T +  S P    T    +STTT  T+  S+    + P T+     L T T
Sbjct: 3891 VP-TTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTT 3949

Query: 1586 EWI-DGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
              +  GS   P  +     T         T     RS+     S P+T      +    S
Sbjct: 3950 TTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSL---PPSSPHTV-----RTAWTS 4001

Query: 1645 HTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHP-TGAQTQT 1703
             T G++       P    ++        T +    ++ P  +  TT   P P T     T
Sbjct: 4002 ATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHT 4061

Query: 1704 TFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPRCTWTKWFDVDFPSPGPH 1763
              T+   + +T   T TS   P  +S T    TT VT  C P+C W++W D  +P PGP 
Sbjct: 4062 RGTSRTTATATPSKTRTSTLLP--SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPS 4119

Query: 1764 GGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQD 1823
            GGD +TY+NI  +G  +C +P     L+CRA++ P V +  LGQVV+CS + GLVCRN++
Sbjct: 4120 GGDFDTYSNIRAAGGAVCEQP---LGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNRE 4176

Query: 1824 QQGPFKMCLNYEVRVLCCETPR--GCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTT 1881
            Q G FKMC NYE+RV CC        P TS+  T  STP    I    +T++     T +
Sbjct: 4177 QVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGS 4236

Query: 1882 LVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASP-ASTT------------ 1928
              T S+T       T   TT+T + PT  T +A +T+ T+ +P  STT            
Sbjct: 4237 TATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT 4296

Query: 1929 --SGPGNTPSPVPTTSTISAPT-TSITSAPTTST-TSAPTSSTTSAPTTSTTSAPTSSTT 1984
              S PG   +     ST + PT TS T+ P++S  T+    S T+ PT + ++A  SST 
Sbjct: 4297 PFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTP 4356

Query: 1985 SSPQTST--TSAPTTSTTSGPGTTPSPVPTT 2013
             +  TST  T+  TT+  +G   TPS  P T
Sbjct: 4357 ETAHTSTVLTTTATTTRATGSVATPSSTPGT 4387



 Score =  239 bits (611), Expect = 2e-62
 Identities = 222/752 (29%), Positives = 325/752 (43%), Gaps = 99/752 (13%)

Query: 1312 ERRVYPCS----PTTPVPPTTFSFSTPP--------LVVSSTHTPSNGPSSAHTGPPSSA 1359
            E RV+ C+    P+TP   +T + S+ P        L  ++T T S G ++  +  P + 
Sbjct: 4188 EIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTT 4247

Query: 1360 WPTTAGTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYR 1419
            W  T         P+ +A++    G     S     +     + +    T+ + +A  + 
Sbjct: 4248 WILTE--------PSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPF- 4298

Query: 1420 VCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPL 1479
                          +PG        R   +     T      +S L   +    Q  TP 
Sbjct: 4299 -------------SSPGTATALPALRSTATTPTA-TSFTAIPSSSLGTTWTRLSQTTTPT 4344

Query: 1480 ACSTSSSP------AQTTPPTTSKTTETRASGSSA-PSSTPGTVSLSTARTTPAPGTATS 1532
            A  ++++P      A T+   T+  T TRA+GS A PSSTPGT   +   TT   G   +
Sbjct: 4345 ATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVT 4404

Query: 1533 VKKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTWTEWIDGSY 1592
               +  T   PPV  ++T     TTP TS  +  P+    +T +      T T    GS 
Sbjct: 4405 PSSSPGTARTPPVWISTT-----TTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSM 4459

Query: 1593 PAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICSHTEGLICL 1652
              P  +     T         T     RS+   + S P+T      +    S T G +  
Sbjct: 4460 ATPSSSTQTSGTTHTPPVPNTTATTHGRSL---SPSSPHTV-----RTAWTSATSGTLGT 4511

Query: 1653 NKNQLPPICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHP-TGAQTQTTFTTHMPS 1711
                 P    ++        T +    ++ P  +  TT   P P T     TT T+   +
Sbjct: 4512 THITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTA 4571

Query: 1712 ASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPRCTWTKWFDVDFPSPGPHGGDKETYN 1771
             +T   T TS   P+  S T    TT VT  C P+C W++W D  +P PGP GGD +TY+
Sbjct: 4572 TATPSKTRTSTLLPS--SPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYS 4629

Query: 1772 NIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMC 1831
            NI  +G  +C +P     L+CRA++ P V +  LGQVV+CS + GLVCRN++Q G FKMC
Sbjct: 4630 NIRAAGGAVCEQP---LGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMC 4686

Query: 1832 LNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTT--- 1888
             NYE+RV CC     CP T      P+T S    S T  T+      TTT  TT++T   
Sbjct: 4687 FNYEIRVFCCNYGH-CPST------PATSSTAMPSSTPGTTWILTELTTTATTTASTGST 4739

Query: 1889 ----STPQTSTTYAHTTSTTSAPTA---RTTSAPTTRTTSASPASTTSGPGNTP---SPV 1938
                STP T+      TS  + PTA   + TS+ + RT +  P  T++   +T    +P+
Sbjct: 4740 ATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPI 4799

Query: 1939 P-----TTSTISAPTT-------SITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSS 1986
            P     TT T+   TT       +I  + T  TT   T  TT A TT  TS+ TS+ +S+
Sbjct: 4800 PSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSS-TSTPSST 4858

Query: 1987 PQTS-----TTSAPTTSTTSGPGTTPSPVPTT 2013
            P T+      T+A TT+  +GP  TPS  P T
Sbjct: 4859 PGTTWILTELTTAATTTAATGPTATPSSTPGT 4890



 Score =  219 bits (559), Expect = 2e-56
 Identities = 193/651 (29%), Positives = 270/651 (41%), Gaps = 120/651 (18%)

Query: 1471 IRVQCCTPLACSTSSSPAQTTPPTTSK----TTETRASGSSAPSSTPGTVSLSTARTTPA 1526
            +R    TP A S ++ P+ +   T ++    TT T    ++ PSSTP TV  ST  TT A
Sbjct: 3163 LRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTA 3222

Query: 1527 PGTATSVKKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELC--TW 1584
              T T    + +TPS  P  A +T  ++TTT G +   S    + P T+  L      T 
Sbjct: 3223 --TTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPS----SSPGTARTLPVWISTTT 3276

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFC---------ESPRSVQCRAESFPNTPLA 1635
            T    GS   P    G   T   L     T            +  S        PNT   
Sbjct: 3277 TPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTAT 3336

Query: 1636 DLGQDVI-----------CSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPP 1684
              G+ +             S T G +       P    ++        T +    ++ P 
Sbjct: 3337 THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPH 3396

Query: 1685 KTVATTRPTPHP-TGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNC 1743
             +  TT   P P T     T  T+   + +T   T TS   P+  S T    TT VT  C
Sbjct: 3397 PSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPS--SPTSAPITTVVTMGC 3454

Query: 1744 HPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIE 1803
             P+C W++W D  +P PGP GGD +TY+NI  +G  +C +P     L+CRA++ P V + 
Sbjct: 3455 EPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP---LGLECRAQAQPGVPLR 3511

Query: 1804 HLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCE--------------TPRGCPV 1849
             LGQVV+CS + GLVCRN++Q G FKMC NYE+RV CC               TP   P 
Sbjct: 3512 ELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPG 3571

Query: 1850 T------------------------STPVTAP------STPSGRAISPTQSTSSWQKSRT 1879
            T                        STP TAP      ST +    + +++TSS      
Sbjct: 3572 TTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTA 3631

Query: 1880 TTLVTTSTTSTPQTSTTY------------------------------AHTTSTTSAPTA 1909
            TTL   ++T+T  T+T++                              + T  TT   T 
Sbjct: 3632 TTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTV 3691

Query: 1910 RTTSAPTTRTTSASPASTTSGPGNT-----PSPVPTTSTISAPTTSITSAPTTS--TTSA 1962
             TT A TTR TS S ++ +S PG T      +   TT+  + PT + +S P T+   T  
Sbjct: 3692 LTTKATTTRATS-SMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEP 3750

Query: 1963 PTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
             T++T + PT ST +A ++  T+      TS  TT T      TPS  P T
Sbjct: 3751 STTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGT 3801



 Score =  217 bits (552), Expect = 1e-55
 Identities = 221/758 (29%), Positives = 304/758 (40%), Gaps = 129/758 (17%)

Query: 1292 HTTDGTGGCISARCGANGTIERRV------YPCSPTTPVPPTTFSFSTPPLVVSSTHTPS 1345
            H T+ + G         GT +         +P S TT  PP+  + +      +S  T +
Sbjct: 4513 HITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTAT 4572

Query: 1346 NGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSG 1405
              PS   T   S+  P++  ++P T + T        C  +C WS W+D S P  G   G
Sbjct: 4573 ATPSKTRT---STLLPSSPTSAPITTVVTTG------CEPQCAWSEWLDYSYPMPGPSGG 4623

Query: 1406 DFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASG- 1464
            DFDT  N+RA G  VCE P  +ECRA+  PGVPL  LGQ V+CS D GL CRNREQ    
Sbjct: 4624 DFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKF 4683

Query: 1465 -LCYNYQIRVQCC-------TPLACST---SSSPAQT---TPPTTSKTTETRASGSSAPS 1510
             +C+NY+IRV CC       TP   ST   SS+P  T   T  TT+ TT      ++ PS
Sbjct: 4684 KMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPS 4743

Query: 1511 STPGTVSLSTARTTPA-PGTATSVKKTFS----TPSPPPVPATSTSSMSTTTPGTSVVSS 1565
            STPGT       T+PA   TATS K T S    T +  PV  TST++ ST T  T +   
Sbjct: 4744 STPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPV-LTSTATKSTATSVTPI--- 4799

Query: 1566 KPTLTEPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCR 1625
             P+ T  +T +  ++  T    +   +P+         T             + ++   R
Sbjct: 4800 -PSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVL-----------TTKATTTR 4847

Query: 1626 AESFPNTPLADLGQDVICSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPPK 1685
            A S  +TP          S T G                        T  +  ++T    
Sbjct: 4848 ATSSTSTP----------SSTPG------------------------TTWILTELTTAAT 4873

Query: 1686 TVATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRN--C 1743
            T A T PT  P+     T   T + + +T   +  S   P++T  T    T P T     
Sbjct: 4874 TTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVT 4933

Query: 1744 HPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIE 1803
             P  +          +  PH     T   +  S       P   T L     +    +  
Sbjct: 4934 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTAT 4993

Query: 1804 HLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGR 1863
                +                  P         R+    TP     T+TP + P      
Sbjct: 4994 SFTAI------------------PSSSLGTTWTRLSQTTTPTATMSTATPSSTPE----- 5030

Query: 1864 AISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSAS 1923
                T  TS+   +  TT   T + +TP ++   AH   TT  PT  TT+   T T S+S
Sbjct: 5031 ----TVHTSTVLTATATTTGATGSVATPSSTPGTAH---TTKVPT--TTTTGFTATPSSS 5081

Query: 1924 PASTTSGPGNTP-SPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSS 1982
            P +  + P  TP S + T  T S P T+ TS   T TT+  T +T S  T S+T   T  
Sbjct: 5082 PGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLT-TTATMTRATNSTATPSSTLGTTRI 5140

Query: 1983 TTSSPQTSTTSAPTTST---TSGPGTT-----PSPVPT 2012
             T    T+TT+A T ST   +S PGTT     PS + T
Sbjct: 5141 LTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIAT 5178



 Score =  209 bits (531), Expect = 3e-53
 Identities = 227/786 (28%), Positives = 323/786 (41%), Gaps = 159/786 (20%)

Query: 1327 TTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTA-------------GTSPRTRLP 1373
            T  S +T P    ST TPS+ P +AHT    +   TT              GT+  T++P
Sbjct: 4335 TRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVP 4394

Query: 1374 TASAS---LPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECR 1430
            T + +   + P        +P + +S     T SG   T              P SV   
Sbjct: 4395 TTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVT--------------PSSV--- 4437

Query: 1431 AEDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSSSPAQT 1490
                PG            +P V LT      A+G            TP + + +S    T
Sbjct: 4438 ----PGTTH---------TPTV-LTTTTTTVATG---------SMATPSSSTQTSGTTHT 4474

Query: 1491 TP-PTTSKTTETRASGSSAP-----------SSTPGTVSLSTART----TPAPGTATSVK 1534
             P P T+ TT  R+   S+P           S T GT  ++   T    TPA  T T+  
Sbjct: 4475 PPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQH 4534

Query: 1535 KTFSTPSPPPVPATSTS--SMSTTTPGTSVVSSKPTLTE-----------PS-------- 1573
             T +  SP P   T+ S  S  TTTPG +  +S+ T T            PS        
Sbjct: 4535 STPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPIT 4594

Query: 1574 ---TSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFP 1630
               T+ C +  C W+EW+D SYP PG +GGDFDT+ N+R  G   CE P  ++CRA++ P
Sbjct: 4595 TVVTTGC-EPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQP 4653

Query: 1631 NTPLADLGQDVICSHTEGLICLNKNQLPP--ICYNYEIRIQCCETVNVCRDITRPPKTVA 1688
              PL +LGQ V CS   GL+C N+ Q+    +C+NYEIR+ CC   +        P T +
Sbjct: 4654 GVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHC----PSTPATSS 4709

Query: 1689 TTRP--TPHPTGAQTQ--TTFTTHMPSASTEQPTATSRGGP------------TATSVTQ 1732
            T  P  TP  T   T+  TT TT   + ST  P++T    P            TATS   
Sbjct: 4710 TAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKA 4769

Query: 1733 GTHTTPVTRNCHPRCTWTKWFDVDF---PSPGPHGGDKETYNNIIRSGEKICRRPEEITR 1789
             + ++P T    P  T T          P P    G   T              PE+ T 
Sbjct: 4770 TSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTL-------------PEQTTT 4816

Query: 1790 -LQCRAKSHPEVSIE--HLGQVV--QCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETP 1844
             +   +  HP  + E  H   V+  + +        +     P    +  E+      T 
Sbjct: 4817 PVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTA 4876

Query: 1845 RGCPVTSTPVTAPSTP--------SGRAISPTQSTSSWQKSRTTTLV-----TTSTTSTP 1891
               P T+TP + P T         +    + T ST++   +  TT +     TT+T + P
Sbjct: 4877 ATGP-TATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVP 4935

Query: 1892 QTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPT-TS 1950
              ST  A +T  T A T   ++  TT T ++S A+ +S PG   +     ST + PT TS
Sbjct: 4936 TGSTATASSTQAT-AGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATS 4994

Query: 1951 ITSAPTTST-TSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGT--TP 2007
             T+ P++S  T+    S T+ PT + ++A  SST  +  TST    T +TT   G+  TP
Sbjct: 4995 FTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATP 5054

Query: 2008 SPVPTT 2013
            S  P T
Sbjct: 5055 SSTPGT 5060



 Score =  189 bits (480), Expect = 2e-47
 Identities = 219/770 (28%), Positives = 296/770 (38%), Gaps = 167/770 (21%)

Query: 1293 TTDGTGGCISARCGANGTIERRVYPCSPTTP-------------VPPTTFSFSTPPLVVS 1339
            TT    G ++      GT      P + TT               PP   S +T P    
Sbjct: 3868 TTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRG 3927

Query: 1340 STHTPSNGPSSAHTGPPSSAWPTTAGT----SPRTRLPTASAS-LPPVCGEKCLWSPWMD 1394
            ST TPS+ P + HT    +   TT  T    +P +   T+  +  PPV        P   
Sbjct: 3928 STVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPV--------PNTT 3979

Query: 1395 VSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGL 1454
             +  GR                      SP +V      A       LG      P   +
Sbjct: 3980 ATTHGRSLPP-----------------SSPHTVRTAWTSATS---GILGTTHITEPST-V 4018

Query: 1455 TCRNREQASGLCYNYQIRVQCCTPLACSTSSSPAQTTPPTTSKTTETRASGSSAPSSTPG 1514
            T       +    +    +    P + +T S P   +P TT+            P  T G
Sbjct: 4019 TSHTPAATTSTTQHSTPALSSPHPSSRTTESPP---SPGTTT------------PGHTRG 4063

Query: 1515 TVSLSTARTTPAPGTATSVKKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPST 1574
                 T+RTT    TAT  K   ST  P         S  T+ P T+VV          T
Sbjct: 4064 -----TSRTT---ATATPSKTRTSTLLP---------SSPTSAPITTVV----------T 4096

Query: 1575 SSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPL 1634
            + C +  C W+EW+D SYP PG +GGDFDT+ N+R  G   CE P  ++CRA++ P  PL
Sbjct: 4097 TGC-EPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPL 4155

Query: 1635 ADLGQDVICSHTEGLICLNKNQLP--PICYNYEIRIQCCETVNVCRDITRPPKTVATTRP 1692
             +LGQ V CS   GL+C N+ Q+    +C+NYEIR+ CC   +     T    + AT   
Sbjct: 4156 RELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHC--PSTPATSSTATPSS 4213

Query: 1693 TPHPTGAQTQ--TTFTTHMPSASTEQP-----------------TATSRGGPTAT-SVTQ 1732
            TP  T   T+  TT TT   + ST  P                 T T   G TAT S TQ
Sbjct: 4214 TPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQ 4273

Query: 1733 GTHTTPVTRNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQC 1792
             T  TP         T T      F SPG       T    +RS           T    
Sbjct: 4274 ATAGTPHVSTTATTPTVTSSKATPFSSPG-----TATALPALRS-----------TATTP 4317

Query: 1793 RAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTST 1852
             A S   +    LG                              R+    TP     T+T
Sbjct: 4318 TATSFTAIPSSSLGTT--------------------------WTRLSQTTTPTATMSTAT 4351

Query: 1853 PVTAPSTPSGRAISPTQSTSSWQ----KSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPT 1908
            P + P T     +  T +T++       + ++T  T  TT  P T+TT    T ++S  T
Sbjct: 4352 PSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGT 4411

Query: 1909 ART----TSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPT 1964
            ART     S  TT TTS S  + +S PG T +P   T+T +   T   + P++ST ++ T
Sbjct: 4412 ARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGT 4471

Query: 1965 SSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGP-GTTPSPVPTT 2013
            + T   P T+ T+   S + SSP T  T+   TS TSG  GTT    P+T
Sbjct: 4472 THTPPVPNTTATTHGRSLSPSSPHTVRTA--WTSATSGTLGTTHITEPST 4519



 Score =  177 bits (449), Expect = 9e-44
 Identities = 190/649 (29%), Positives = 248/649 (38%), Gaps = 108/649 (16%)

Query: 1326 PTTFSFSTPPLVVSSTH--TP---SNGPSSAHTGPPSSAWPTTAG--------------- 1365
            P+T +  TP    S+T   TP   S  PSS  T  P S   TT G               
Sbjct: 4015 PSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPS 4074

Query: 1366 -TSPRTRLPTASASLPPV------CGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGY 1418
             T   T LP++  S P        C  +C WS W+D S P  G   GDFDT  N+RA G 
Sbjct: 4075 KTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGG 4134

Query: 1419 RVCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASG--LCYNYQIRVQCC 1476
             VCE P  +ECRA+  PGVPLR LGQ V+CS D GL CRNREQ     +C+NY+IRV CC
Sbjct: 4135 AVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCC 4194

Query: 1477 TPLACSTSSSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKT 1536
                C +       TP T+S  T         PSSTPGT  + T  TT    TAT+ + T
Sbjct: 4195 NYGHCPS-------TPATSSTAT---------PSSTPGTTWILTKLTT----TATTTEST 4234

Query: 1537 FSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCL----QELCTWTEWIDGSY 1592
             ST +P   P T+      +T  T  V +  T T  ST +            T  +  S 
Sbjct: 4235 GSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSK 4294

Query: 1593 PAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQ-----DVICSHTE 1647
              P  + G       LR    T           A SF   P + LG          + T 
Sbjct: 4295 ATPFSSPGTATALPALRSTATT---------PTATSFTAIPSSSLGTTWTRLSQTTTPTA 4345

Query: 1648 GLICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQTQTTFTT 1707
             +     +  P   +   +      T      +  P  T  T   T  PT   T TT  T
Sbjct: 4346 TMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPT---TTTTGFT 4402

Query: 1708 HMPSASTEQPTATSRGGPT--ATSVTQGTHTTPVTRNCHPRCTWTKWFDVDFPSPGPHGG 1765
              PS+S      T+R  P   +T+ T  T  + VT +  P  T T    +   +     G
Sbjct: 4403 VTPSSS----PGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTV-LTTTTTTVATG 4457

Query: 1766 DKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQ 1825
               T ++  ++       P   T      +S    S  H  +    S   G +       
Sbjct: 4458 SMATPSSSTQTSGTTHTPPVPNTTATTHGRS-LSPSSPHTVRTAWTSATSGTLGTTH--- 4513

Query: 1826 GPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTT 1885
                            E   G   T    T  +  S  A+S     S    SRTT    +
Sbjct: 4514 --------------ITEPSTGTSHTPAATTGTTQHSTPALS-----SPHPSSRTTESPPS 4554

Query: 1886 STTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNT 1934
              T+TP       HTT+T+   T  T +   TRT++  P+S TS P  T
Sbjct: 4555 PGTTTP------GHTTATSR--TTATATPSKTRTSTLLPSSPTSAPITT 4595



 Score =  164 bits (415), Expect = 8e-40
 Identities = 94/295 (31%), Positives = 142/295 (48%), Gaps = 28/295 (9%)

Query: 802  CAAPMVFFDCRNATPGDTGAGCQKSCHTLDMT-CYSPQCVPGCVCPDGLVAD--GEGGCI 858
            C   M + +CR+         C  +C   + +      CV GC CP+G V D  G+ GC+
Sbjct: 338  CPNNMQYHECRSP--------CADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCV 389

Query: 859  TAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQS 918
                C CV+N A+Y  G T    C  CTC    W C + PC  TC+V G  H+ TFDG+ 
Sbjct: 390  PVSKCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQ 449

Query: 919  YSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGT-TCSKAIKIFLGGFE-LKLS 976
            Y+ +GDC Y L       K     +F V+ E   CG T + TC K++ + L G + + + 
Sbjct: 450  YTVHGDCSYVLT------KPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVI 503

Query: 977  HGKVEVIGTDESQEVPYT------IRQMGIYLVVDTDIGLVLLWD--KKTSIFINLSPEF 1028
                EV       ++P +       R    +++  T +GL L         +F+ L+P+ 
Sbjct: 504  KASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKL 563

Query: 1029 KGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDAL-APKDPCT 1082
            +G+ CGLCGNF+ I  +DF T S  V      F N++K   +CP+   + +DPC+
Sbjct: 564  RGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCS 618



 Score =  148 bits (374), Expect = 5e-35
 Identities = 106/368 (28%), Positives = 159/368 (43%), Gaps = 37/368 (10%)

Query: 903  CAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSK 962
            C+ +G  HY TFDG  + F G C Y   + HCG   +  + F +           T    
Sbjct: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSE-HCG---AAYEDFNIQLRRSQESAAPTLSRV 136

Query: 963  AIKIFLGGFELKLSHGKVEVIGTDESQEVPYT-----IRQMGIYLVVDTDIGLVLLWDKK 1017
             +K+   G  ++L+ G V V G      +P++     I+Q   Y  V+  +GLVL+W+  
Sbjct: 137  LMKV--DGVVIQLTKGSVLVNG--HPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHD 192

Query: 1018 TSIFINLSPEFKGRVCGLCGNFDDI-AVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALA 1076
             S+ + L  ++  + CGLCG+F+ +  V++  + +  +    +EFGN  K+         
Sbjct: 193  DSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNLQKMDDPTEQC-- 248

Query: 1077 PKDPCTANPFRKSWAQKQCS-ILHGPTFAACHAHVEPARYYEACVNDACACDSGGDCECF 1135
             +DP    P   S     C  +LHG  F+ C A V+   Y EAC  D C C+      C 
Sbjct: 249  -QDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCV 307

Query: 1136 CTAVAAYAQAC-HEVGLCVSWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRG 1194
            C  +A Y++ C H  GL   WR P  CP  C            Y  C  PC  TC N   
Sbjct: 308  CHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPN-------NMQYHECRSPCADTCSNQEH 360

Query: 1195 DCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDK 1254
                +   + GC+  CP    + D  +  CV     P     C  +G +Y PGA   +D 
Sbjct: 361  SRACEDHCVAGCF--CPEGTVLDDIGQTGCV-----PVSKCACVYNGAAYAPGATYSTD- 412

Query: 1255 NCQSCLCT 1262
             C +C C+
Sbjct: 413  -CTNCTCS 419



 Score =  142 bits (359), Expect = 3e-33
 Identities = 115/372 (30%), Positives = 161/372 (43%), Gaps = 26/372 (6%)

Query: 434 CSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLS 493
           CS  G  H+ TFDG  +   G C+YV ++ C ++      +LRR   + + T L  V + 
Sbjct: 81  CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPT-LSRVLMK 139

Query: 494 LDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTM 553
           +DGV   V+    G V +N     LP S + V I + S++  + +  LGL L      + 
Sbjct: 140 VDGV---VIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKV-EARLGLVLMWNHDDS- 194

Query: 554 QLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSF 613
            L ++L  K   +TCGLCG+FN +       LS   + T   F N  K      +     
Sbjct: 195 -LLLELDTKYANKTCGLCGDFNGMPVVS-ELLSHNTKLTPMEFGNLQKMD----DPTEQC 248

Query: 614 EDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSE--DCL 671
           +DP      N       C +L      F  C A V  G+Y   C  D C CE ++   C+
Sbjct: 249 QDPVPEPPRNCSTGFGICEELLHGQ-LFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCV 307

Query: 672 CAALSSYVHACAAKGVQLGGWRD-GVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDIT 730
           C  L+ Y   C   G     WR    C +    CP +M YH   S C  TC S  E    
Sbjct: 308 CHTLAEYSRQCTHAGGLPQDWRGPDFCPQK---CPNNMQYHECRSPCADTC-SNQEHSRA 363

Query: 731 CSVGFIPVDGCICPKGTFLDDTGK--CVQASNCPCYHRGSMIPNGESVHDSGAICTCTHG 788
           C    +   GC CP+GT LDD G+  CV  S C C + G+    G +       CTC+ G
Sbjct: 364 CEDHCVA--GCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGG 421

Query: 789 KLSCIGGQAPAP 800
           + SC   + P P
Sbjct: 422 RWSC--QEVPCP 431



 Score =  116 bits (291), Expect = 2e-25
 Identities = 138/542 (25%), Positives = 201/542 (37%), Gaps = 77/542 (14%)

Query: 416  CTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAEL 475
            C C GGR      P  G CS+ GG+H+STFDG  YT  G+C+YVL +   +    +   L
Sbjct: 5395 CECVGGRGI---TPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYL 5451

Query: 476  RRCGLTDSET-------CLKSVTL---SLDGVQTVVVIKASGEVFLNQIYTQLPISAANV 525
                 T S T       C +++++   S+D V TV ++    E  +  ++ Q+P+S+   
Sbjct: 5452 DNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLI--LFDQIPVSSG-- 5507

Query: 526  TIFRPSTFFI--IAQTSLGLQ---LNLQLVPTMQLFMQLAPK--LRGQTCGLCGNFNSIQ 578
              F  +   +  +  T++ +    L + +    Q+F    P       T G CG   + Q
Sbjct: 5508 --FSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQ 5565

Query: 579  ADDFRTLSGVVEATAAAFFNTFKTQ----------AACPNIRNSFEDPCSLSVENEKYAQ 628
             DD     G   A+      T+                P   +      S         Q
Sbjct: 5566 RDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ 5625

Query: 629  HWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQ 688
              C  +      F  CH  V PG +++ C+ D  +C    +  C +L +Y   C A+GV 
Sbjct: 5626 PLCDLMLSQ--VFAECHNLVPPGPFFNACISD--HCRGRLEVPCQSLEAYAELCRARGV- 5680

Query: 689  LGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTF 748
               WR         TCP +  Y         TC S ++      +     +GC CP+   
Sbjct: 5681 CSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQLEGM----AEGCFCPEDQI 5736

Query: 749  LDDT--GKCVQASNCPCY-HRGSMIPNGESVHDSGAICTCTHGKLSC------IGGQAPA 799
            L +   G CVQA  CPC    G     GE    +   C C  G +S          Q   
Sbjct: 5737 LFNAHMGICVQA--CPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQGQP 5794

Query: 800  PVCAAPMVFFDCRNATPGDTGAGCQKS-CHTLDMTCYSPQCVPGCVCPDG---LVADGEG 855
            P C  P      R   P      C ++ C     TC  PQ +P  VCP G   +    EG
Sbjct: 5795 PPCNRPGFVTVTR---PRAENPCCPETVCVCNTTTC--PQSLP--VCPPGQESICTQEEG 5847

Query: 856  GCITAEDCP---CVHNEASYRAGQTI--RVGCNTCTC-----DSRMWRCTDDPCLATCAV 905
             C     C    C +N   Y  G T    + C+ CTC          +C +D C  T   
Sbjct: 5848 DCCPTFRCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCP 5907

Query: 906  YG 907
             G
Sbjct: 5908 QG 5909



 Score =  113 bits (283), Expect = 2e-24
 Identities = 107/411 (26%), Positives = 159/411 (38%), Gaps = 60/411 (14%)

Query: 898  PCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQN-HCG-GKDSTQDSFRVVTENVPCGT 955
            P    C+++G  HY TFDG SY+F G+C Y L++  H   G  S        T +     
Sbjct: 5405 PGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAA 5464

Query: 956  TGTTCSKAIKIFLGGFELKLS----HGKVEVIGTDESQEVPYTIRQMGIYLVVDTDIGLV 1011
                C +A+ I     ++ L+    HGK E +   +   V     + G+ + V   +G  
Sbjct: 5465 AAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSV---LGTT 5521

Query: 1012 LLWDKKTSIFINLSPEFKGRVC--------------GLCGNFDDIAVNDFATRSRSVVGD 1057
             +  +     + +S  F G+V               G CG   +   +D   R  +    
Sbjct: 5522 TM--RVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAAS 5579

Query: 1058 VLEFGNSWKLSPS----------CPDALAPKDPCTANPFRKSW-AQKQCSILHGPTFAAC 1106
              +   +W +  S           P   +P  P ++ P       Q  C ++    FA C
Sbjct: 5580 CKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAEC 5639

Query: 1107 HAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWR--TPSICPLF 1164
            H  V P  ++ AC++D C     G  E  C ++ AYA+ C   G+C  WR  T  +C L 
Sbjct: 5640 HNLVPPGPFFNACISDHCR----GRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLT 5695

Query: 1165 CDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQC 1224
            C    P  +    Y+PCG     TC N R    +     EGC+  CP +  +F+     C
Sbjct: 5696 C----PPTKV---YKPCGPIQPATC-NSRNQSPQLEGMAEGCF--CPEDQILFNAHMGIC 5745

Query: 1225 VATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEAC 1275
            V  CP           G    PG    S  NCQSC+C E  V    K   C
Sbjct: 5746 VQACPC------VGPDGFPKFPGERWVS--NCQSCVCDEGSVSVQCKPLPC 5788



 Score =  108 bits (271), Expect = 4e-23
 Identities = 105/391 (26%), Positives = 156/391 (39%), Gaps = 51/391 (13%)

Query: 80   VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSR---- 135
            +CS WG  HY TFDG  + F G C YV      A + + ++ L     +A+ T +     
Sbjct: 5409 ICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAAR 5468

Query: 136  ------VLMKVDGVVIQLT------KGSVLVNGHPVLLPFSQSGVLIQQSSSYT-KVEA- 181
                  +  K   +V+ +T      +G +L +  PV   FS++GVL+    + T +V+  
Sbjct: 5469 CPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIP 5528

Query: 182  RLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKM 241
             LG+ + +N          + + N T G CG          L    T  T     ++ K 
Sbjct: 5529 ALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGT--TAASCKDMAKT 5586

Query: 242  ----DDPTEQCQDPVPEPPRNCSTG-------------FGICEELLHGQLFSGCVALVDV 284
                D   + C  P   PP                     +C+ +L  Q+F+ C  LV  
Sbjct: 5587 WLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLML-SQVFAECHNLVPP 5645

Query: 285  GSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPD--FCPQKCPNNM 342
            G +  AC  D C       L   C +L  Y+  C  A G+  DWRG     C   CP   
Sbjct: 5646 GPFFNACISDHC----RGRLEVPCQSLEAYAELC-RARGVCSDWRGATGGLCDLTCPPTK 5700

Query: 343  QYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVY-NGA 401
             Y  C      TC+++  S   E     GCFCPE  +L +     CV    C CV  +G 
Sbjct: 5701 VYKPCGPIQPATCNSRNQSPQLEG-MAEGCFCPEDQILFNAHMGICVQA--CPCVGPDGF 5757

Query: 402  AYAPGATYSTDCTNCTCSGGRWS--CQEVPC 430
               PG  + ++C +C C  G  S  C+ +PC
Sbjct: 5758 PKFPGERWVSNCQSCVCDEGSVSVQCKPLPC 5788



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 53/177 (29%), Positives = 85/177 (48%), Gaps = 12/177 (6%)

Query: 1848 PVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAP 1907
            P+ S  +    T   +  +P  + S+   S T     TST  T + +TT A ++ +T + 
Sbjct: 3651 PIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSS 3710

Query: 1908 TARTTSAPTTRTTSASPASTTSGPGNTPSPVP----------TTSTISAPTTSITSAPTT 1957
            T  TT   T  TT+A+  + T GP  TPS  P          TT+T++ PT S  +A +T
Sbjct: 3711 TPGTTWILTELTTAATTTAAT-GPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASST 3769

Query: 1958 STTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGP-GTTPSPVPTT 2013
              T+      TS  TT T  +  ++ +SSP T+T      ST + P  T+ + +P++
Sbjct: 3770 RATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSS 3826



 Score = 55.1 bits (131), Expect = 7e-07
 Identities = 75/297 (25%), Positives = 110/297 (37%), Gaps = 29/297 (9%)

Query: 1286 PGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPLVVSSTHTPS 1345
            PG     T   T   ++   G+  T        +  T   P   + +T P V SS  TPS
Sbjct: 4917 PGTTWILTEPSTTATVTVPTGSTATASS-----TQATAGTPHVSTTATTPTVTSSKATPS 4971

Query: 1346 NGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRGT--- 1402
            + P +A   P   +  TT   +  T +P++S           L + W  +S+    T   
Sbjct: 4972 SSPGTATALPALRSTATTPTATSFTAIPSSS-----------LGTTWTRLSQTTTPTATM 5020

Query: 1403 -DSGDFDTLENLRAHGYRVCESPRSVECRAEDAPG-VPLRALGQRVQCSPDVGLTCRNRE 1460
              +    T E +         +  +    +   P   P  A   +V  +   G T     
Sbjct: 5021 STATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTA-TPS 5079

Query: 1461 QASGLCYNYQIRVQCCTPLACSTSSSPAQTTPPT--TSKTTETRASGSSA-PSSTPGTVS 1517
             + G            T     TSS+P  T   T  T+  T TRA+ S+A PSST GT  
Sbjct: 5080 SSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTR 5139

Query: 1518 LSTARTTPAPGTATSVKKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPST 1574
            + T  TT    TAT+   T ST +    P T+      +T  T +V +  T T  ST
Sbjct: 5140 ILTELTT----TATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASST 5192



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 25/70 (35%), Positives = 36/70 (51%), Gaps = 1/70 (1%)

Query: 1265 GVECTYKAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPV 1324
            G   ++ +  C C   GQ F PG+VIY+ TD  G    A C  +  I+R    C PT+P 
Sbjct: 5255 GFPSSHFSTPCFCRAFGQFFSPGEVIYNKTDRAGCHFYAVCNQHCDIDRFQGAC-PTSPP 5313

Query: 1325 PPTTFSFSTP 1334
            P ++   S+P
Sbjct: 5314 PVSSAPLSSP 5323



 Score = 40.0 bits (92), Expect = 0.023
 Identities = 61/258 (23%), Positives = 93/258 (36%), Gaps = 27/258 (10%)

Query: 1327 TTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTAS------ASLP 1380
            T  S +T P    ST TPS+ P + HT    +A  TT G +     P+++        +P
Sbjct: 5008 TRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVP 5067

Query: 1381 PVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRA-HGYRVCESPRSVECRAEDAPGVPL 1439
                     +P    S PG          +  +   H     E+  +       A     
Sbjct: 5068 TTTTTGFTATP---SSSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTA--TMT 5122

Query: 1440 RALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSSSPAQT---TPPTTS 1496
            RA       S  +G T    E  +             T    + SS+P  T   T P+T 
Sbjct: 5123 RATNSTATPSSTLGTTRILTELTT------TATTTAATGSTATLSSTPGTTWILTEPSTI 5176

Query: 1497 KTTETRASGSSAPSSTPGTV---SLSTARTTPAPGTATSV--KKTFSTPSPPPVPATSTS 1551
             T       ++  SST GT     + T   T    TA++V    T  T   P V  +S  
Sbjct: 5177 ATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLP 5236

Query: 1552 SMSTTTPGTSVVSS-KPT 1568
            + S +T  +SV+++ +PT
Sbjct: 5237 TFSVSTVSSSVLTTLRPT 5254



 Score = 40.0 bits (92), Expect = 0.023
 Identities = 34/120 (28%), Positives = 40/120 (33%), Gaps = 21/120 (17%)

Query: 335  PQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGC---FCPEGTVLDDIGQTG---- 387
            P  C    Q   C  P   T +       C    V  C    CP+   +   GQ      
Sbjct: 5785 PLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQ 5844

Query: 388  ----CVPVSKCA---CVYNGAAYAPGATY--STDCTNCTCSGG-----RWSCQEVPCPGT 433
                C P  +C    C YNG  Y  GAT+  +  C  CTC  G        CQE  C  T
Sbjct: 5845 EEGDCCPTFRCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNT 5904


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 1516 bits (3924), Expect = 0.0
 Identities = 776/1723 (45%), Positives = 1009/1723 (58%), Gaps = 115/1723 (6%)

Query: 70   RASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRS--QE 127
            R  N  HN  VCSTWG+FHYKTFDGDVFRFPGLC+Y F+  C  +Y++F + L+R   Q 
Sbjct: 28   RTRNHGHN--VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQA 85

Query: 128  SAAPTLSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVL 187
             A   +  +L+ +    I LT+   ++NG  V  P    G+LI++S +YTKV +R GL L
Sbjct: 86   EAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTL 145

Query: 188  MWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDDPTEQ 247
            MWN +D+L+LELDTK+ N TCGLCGD+NG+   SE LS     +P+EFGN+QK++ P   
Sbjct: 146  MWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVV 205

Query: 248  CQDPVPE-PPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSC 306
            C+DP  E  P +CS     CE LL  + F+ C  LV +  YL AC+QD C C   D  +C
Sbjct: 206  CEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGD--TC 263

Query: 307  VCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACED 366
            VC T+AE+SRQC+HAGG P +WR    CP+ CP N+ Y E  SPC DTCS+ E S  CE+
Sbjct: 264  VCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEVSSLCEE 323

Query: 367  HCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQ 426
            H + GCFCPEGTV DDIG +GCVPVS+C C  +G  Y PG   + DC  C C+ GRW C+
Sbjct: 324  HRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEITNDCEQCVCNAGRWVCK 383

Query: 427  EVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETC 486
            ++PCPGTC++ GG+H +TFDGK YT HGDC YVL K   + ++ +L EL  CG TD +TC
Sbjct: 384  DLPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELAPCGSTDKQTC 443

Query: 487  LKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLN 546
            LK+V L  D  + VVV K+ G V LN++   LP   A+ ++FRPS++ I+   ++G++L 
Sbjct: 444  LKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQ 503

Query: 547  LQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAAC 606
            +QL P MQLF+ L    +GQ  GLCGNFN ++ DDF+T SG+VEAT A F NT+K Q++C
Sbjct: 504  VQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSC 563

Query: 607  PNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCER 666
             +  +  +DPCSL++E+  YA+HWCS L   + PFGRCH+AV P  YY  C +DTCNC+ 
Sbjct: 564  HDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQN 623

Query: 667  SEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSE 726
            +EDCLCAALSSY  AC AKGV L GWR+ VC K + +CP S  + Y+++TCQ TCRSLSE
Sbjct: 624  NEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE 683

Query: 727  GDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCT 786
             D  C  GF PVDGC CP  TFLD+ G+CV  + C CYHRG  +  G+ V      C C 
Sbjct: 684  ADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCR 743

Query: 787  HGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCP 846
             G+L C   +     C AP +  DC N T   T      SC TL    Y  +CV GCVCP
Sbjct: 744  DGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCP 803

Query: 847  DGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVY 906
            DGL+ DG GGC+  ++CPCVHN   Y +G  I+V CNTCTC    W CT   C  TC++Y
Sbjct: 804  DGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIY 863

Query: 907  GDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKI 966
            G GHY+TFDG+ Y F+G C Y  VQ++C G++S+  SF ++TENVPCGTTG TCSKAIKI
Sbjct: 864  GSGHYITFDGKYYDFDGHCSYVAVQDYC-GQNSSLGSFSIITENVPCGTTGVTCSKAIKI 922

Query: 967  FLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSP 1026
            F+G  ELKL      VI  DE   V YT R++G YLVV++  G++++WDK+T++FI L+P
Sbjct: 923  FMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAP 982

Query: 1027 EFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPKDPCTANPF 1086
             +KG VCGLCGNFD  + NDF TR   VV   L+FGNSWK +P+CPD     +PC+ NP 
Sbjct: 983  SYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPH 1042

Query: 1087 RKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQAC 1146
            R+SWA+KQCSIL    F+ CH+ V+P  +YEACV+D+C+CD+GGDCECFC+AVA+YAQ C
Sbjct: 1043 RRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQEC 1102

Query: 1147 HEVGLCVSWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRG-DCLRDVWGLEG 1205
             + G CV WRTP +CP+FCDYYNP  +CEWHY+PCG     TCR   G      V  LEG
Sbjct: 1103 TKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEG 1162

Query: 1206 CYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERG 1265
            CYP+CP + PI++ED  +CV           C+V    Y PGA VP+++ C+SC+CT   
Sbjct: 1163 CYPRCPKDRPIYEEDLKKCVTADKC-----GCYVEDTHYPPGASVPTEETCKSCVCT--- 1214

Query: 1266 VECTYKAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTT-PV 1324
                  +   VC     R   G ++  T DG   C    CG NGT+E+    CS TT P 
Sbjct: 1215 -----NSSQVVC-----RPEEGKILNQTQDG-AFCYWEICGPNGTVEKHFNICSITTRPS 1263

Query: 1325 PPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASL---PP 1381
              TTF+  T P                         PTT  T+  T  PT+S  L   P 
Sbjct: 1264 TLTTFTTITLPTT-----------------------PTTFTTTTTTTTPTSSTVLSTTPK 1300

Query: 1382 VCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLRA 1441
            +C   CLWS W++   P  G+D GD +T +        VC +P  +ECR+   P + L  
Sbjct: 1301 LC---CLWSDWINEDHPSSGSDDGDRETFDG-------VCGAPEDIECRSVKDPHLSLEQ 1350

Query: 1442 LGQRVQCSPDVGLTCRNREQAS----GLCYNYQIRVQCCTPL-ACSTSSSPAQTT--PPT 1494
            LGQ+VQC   VG  C+N +Q      GLCY+Y+IRV CC P+  C T+ SP  TT  PP 
Sbjct: 1351 LGQKVQCDVSVGFICKNEDQFGNGPFGLCYDYKIRVNCCWPMDKCITTPSPPTTTPSPPP 1410

Query: 1495 TSKTTETRASGSSAPSST----PGTVSLS---TARTTPAPGTATSVKKTFSTPSPP---P 1544
            TS TT    +  S P++T    P T + S   T  TTP P T  S   + +T  PP   P
Sbjct: 1411 TSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTP 1470

Query: 1545 VPATSTSSMSTTTPG---TSVVSSKPTLT-EPSTSSCLQELCTWTEWIDGSYPAPGINGG 1600
             P T+T S  TTTP    T+  +  PT T  P T++ +    + T     + P+P     
Sbjct: 1471 SPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTT-- 1528

Query: 1601 DFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICSHTEGLICLNKNQLPPI 1660
                         T    P +      + P TP          + T  L        PP 
Sbjct: 1529 ------------TTTTPPPTTTPSPPTTTPITP---------PTSTTTLPPTTTPSPPPT 1567

Query: 1661 CYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQTQTTFTTHMPSASTEQPTAT 1720
                        T +     T  P T+ TT P P  T +   TT TT  P+ +   PT T
Sbjct: 1568 TTTTP---PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1624

Query: 1721 SRGGPTATSVTQGTHT---TPVTRNCHPRCTWTKWFDVDFPSP 1760
                PT+T+    T T    P T    P  T         PSP
Sbjct: 1625 PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP 1667



 Score =  223 bits (569), Expect = 1e-57
 Identities = 210/723 (29%), Positives = 288/723 (39%), Gaps = 83/723 (11%)

Query: 1317 PCSPTTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTAS 1376
            P   TTP PPTT   + PP   SS  T +  P S  T P  S + TT  T+P        
Sbjct: 1731 PSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSI-TPPTFSPFSTTTPTTP-------- 1781

Query: 1377 ASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPG 1436
                  C   C W+ W+D  +P      GD + + ++   G+       ++ CRA   P 
Sbjct: 1782 ------CVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAA-----NISCRATMYPD 1830

Query: 1437 VPLRALGQRVQCSPDVGLTCRNREQASG------LCYNYQIRVQCC---TPLACSTSSSP 1487
            VP+  LGQ V C   VGL C+N +Q  G       C NY+I VQCC   T     T+++ 
Sbjct: 1831 VPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTT 1890

Query: 1488 AQTTPPTTSKTTETRA-------SGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTP 1540
               TPPTT+  T T         +G+  P++TP T + +   T    GT T      +T 
Sbjct: 1891 ENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1950

Query: 1541 SP-PPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTWTEWIDGSYPAPGING 1599
            +   P P  + +   TTTP T+  +  PT T   T +      T T  +    P P   G
Sbjct: 1951 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT---PTPTPTG 2007

Query: 1600 GDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICSHTEGLICLNKNQLPP 1659
                T   +     T   +P       ++   TP+         + T            P
Sbjct: 2008 TQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPTPTGTQTPTTTP 2061

Query: 1660 ICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQTQTTFTTHMPSASTEQPTA 1719
            I     +      T       T P  T  T  PTP PTG QT TT      +  T  PT 
Sbjct: 2062 ITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2120

Query: 1720 TSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRS 1776
            T    PT T +T  T  TP    T    P  T         P+P P G    T   I  +
Sbjct: 2121 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2180

Query: 1777 GEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEV 1836
                       T      ++     I     V       G        Q P    +    
Sbjct: 2181 ------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQTPTTTPITTTT 2227

Query: 1837 RVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTP----- 1891
             V    TP G   T TP T P T +   ++PT + +  Q + TTT +TT+TT TP     
Sbjct: 2228 TVTPTPTPTG---TQTPTTTPITTT-TTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPT 2282

Query: 1892 --QTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTT 1949
              QT TT   TT+TT  PT   T    T+T + +P +TT+    TP+P  T +  + P T
Sbjct: 2283 GTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2339

Query: 1950 SITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSP 2009
            + T+   T T +   + TT+  TT+TT  PT + T + QT TT+  TT+TT     TP+P
Sbjct: 2340 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTT----VTPTP 2394

Query: 2010 VPT 2012
             PT
Sbjct: 2395 TPT 2397



 Score =  222 bits (565), Expect = 3e-57
 Identities = 153/392 (39%), Positives = 207/392 (52%), Gaps = 61/392 (15%)

Query: 1641 VICSHTEGLICLNKNQLPPICYNYEIRIQCC-------ETVNVCRDITRPPKTVATTRPT 1693
            V+C   EG I LN+ Q    CY +EI    C       +  N+C   TRP          
Sbjct: 1219 VVCRPEEGKI-LNQTQDGAFCY-WEI----CGPNGTVEKHFNICSITTRP---------- 1262

Query: 1694 PHPTGAQTQTTFTT-HMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPRCTWTKW 1752
                   T TTFTT  +P+  T   T T+   PT+++V     TTP  + C   C W+ W
Sbjct: 1263 ------STLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLS---TTP--KLC---CLWSDW 1308

Query: 1753 FDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCS 1812
             + D PS G   GD+ET++ +       C  PE+I   +CR+   P +S+E LGQ VQC 
Sbjct: 1309 INEDHPSSGSDDGDRETFDGV-------CGAPEDI---ECRSVKDPHLSLEQLGQKVQCD 1358

Query: 1813 REEGLVCRNQDQ--QGPFKMCLNYEVRVLCCETPRGCPVT-STPVTAPS-TPSGRAISPT 1868
               G +C+N+DQ   GPF +C +Y++RV CC     C  T S P T PS  P+     P 
Sbjct: 1359 VSVGFICKNEDQFGNGPFGLCYDYKIRVNCCWPMDKCITTPSPPTTTPSPPPTSTTTLPP 1418

Query: 1869 QSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTT 1928
             +T S   + TTT   T+T S P T+TT    T+T S P + TT+ P T TT + P +T 
Sbjct: 1419 TTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPT-TTPSPPTTTP 1477

Query: 1929 SGPGNTPSPVPTTSTISAPTTSITSAPTT-------STTSAPTSSTTSAPTTSTTSAPTS 1981
            S P  TPSP PTT+T + P T+  S PTT       STT+ P ++T S PTT+TT+ P +
Sbjct: 1478 SPPTTTPSP-PTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPT 1536

Query: 1982 STTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
            +T S P T+  + PT++TT  P TTPSP PTT
Sbjct: 1537 TTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1568



 Score =  219 bits (559), Expect = 2e-56
 Identities = 215/729 (29%), Positives = 289/729 (39%), Gaps = 117/729 (16%)

Query: 1321 TTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWP----TTAGTSPRTRLPTAS 1376
            TTP PP T + + PP     T TPS  P++  T PP +  P    TT  T P T  P+  
Sbjct: 1404 TTPSPPPTSTTTLPP-----TTTPSP-PTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPP 1457

Query: 1377 ASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPG 1436
             S           SP      P   T S    T              P +        P 
Sbjct: 1458 ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTT---------PPPTTTPSPPTTTPI 1508

Query: 1437 VP---LRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLA--CSTSSSPAQTT 1491
             P      L      SP    T       +             TP+    ST++ P  TT
Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPTTTP-------SPPTTTPITPPTSTTTLPPTTT 1561

Query: 1492 P--PTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTPSPPPVPATS 1549
            P  P T+ TT    +  S P++T  T S  T  TT  P T T    T +T +PPP    S
Sbjct: 1562 PSPPPTTTTTPPPTTTPSPPTTT--TPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPS 1619

Query: 1550 TSSMSTTTPGTSVVSSKPTLT--EPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQN 1607
              + +  TP TS  +  PT T   P T++      T       + P+P I          
Sbjct: 1620 PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTT 1679

Query: 1608 LRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICSHTEGLICLNKNQLPPICYNYEIR 1667
                  T   SP +      S   TP + +      S T                     
Sbjct: 1680 TPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSST--------------------- 1718

Query: 1668 IQCCETVNVCRDITRPPKTVATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTA 1727
                           PP T  TT P+P  T +   TT TT +P  +T  P  T+   P+ 
Sbjct: 1719 -----------TTPSPPPTTMTT-PSPTTTPSPPTTTMTT-LPPTTTSSPLTTTPLPPSI 1765

Query: 1728 TSVT-QGTHTTPVTRNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEE 1786
            T  T     TT  T  C P C WT W D   P+    GGD E   ++          P  
Sbjct: 1766 TPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVC--------GPGW 1817

Query: 1787 ITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQG----PFKMCLNYEVRVLCCE 1842
               + CRA  +P+V I  LGQ V C    GL+C+N+DQ+     P   CLNYE+ V CCE
Sbjct: 1818 AANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCE 1877

Query: 1843 ------------TPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTST 1890
                        T    P T+TP+T  +T     ++PT + +  Q + TTT +TT+TT T
Sbjct: 1878 CVTQPTTMTTTTTENPTPPTTTPITTTTT-----VTPTPTPTGTQ-TPTTTPITTTTTVT 1931

Query: 1891 P-------QTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTST 1943
            P       QT TT   TT+TT  PT   T    T+T + +P +TT+    TP+P  T + 
Sbjct: 1932 PTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTVTPTPTPTGTQTP 1988

Query: 1944 ISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGP 2003
             + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT TT+  TT+TT   
Sbjct: 1989 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTT--- 2044

Query: 2004 GTTPSPVPT 2012
              TP+P PT
Sbjct: 2045 -VTPTPTPT 2052



 Score =  206 bits (523), Expect = 2e-52
 Identities = 214/729 (29%), Positives = 282/729 (38%), Gaps = 160/729 (21%)

Query: 1317 PCSPTTPVPPTTFSFSTPPLVVSS---THTPSNGPSSAHTGPPSS--AWPTTAGTSPRTR 1371
            P   TTP PPTT    TPP   ++   T TPS  P++  T PP++  + PTT   SP   
Sbjct: 1612 PPPTTTPSPPTTTPI-TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP--- 1667

Query: 1372 LPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRA 1431
             P  + + PP         P    S P   T S    T+            SP +     
Sbjct: 1668 -PITTTTTPP---------PTTTPSSPITTTPSPPTTTM---------TTPSPTTTPSSP 1708

Query: 1432 EDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSSSPAQTT 1491
                  P           P   +T                     TP   +T S      
Sbjct: 1709 ITTTTTP---SSTTTPSPPPTTMT---------------------TPSPTTTPS------ 1738

Query: 1492 PPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTPSPPPVPATSTS 1551
            PPTT+ TT             P T       TT +P T        +TP PP +   + S
Sbjct: 1739 PPTTTMTT------------LPPT-------TTSSPLT--------TTPLPPSITPPTFS 1771

Query: 1552 SMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDE 1611
              STTTP T  V                 LC WT W+D   P     GGD +   ++   
Sbjct: 1772 PFSTTTPTTPCV----------------PLCNWTGWLDSGKPNFHKPGGDTELIGDVCGP 1815

Query: 1612 GYTFCESPRSVQCRAESFPNTPLADLGQDVICSHTEGLICLNKNQLP------PICYNYE 1665
            G+       ++ CRA  +P+ P+  LGQ V+C  + GLIC N++Q P        C NYE
Sbjct: 1816 GWA-----ANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYE 1870

Query: 1666 IRIQCCE------------TVNVCRDITRPPKTVATTRPTPHPTGAQTQTTFTTHMPSAS 1713
            I +QCCE            T N     T P  T  T  PTP PTG QT TT      +  
Sbjct: 1871 INVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 1930

Query: 1714 TEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFPSPGPHGGDKETY 1770
            T  PT T    PT T +T  T  TP    T    P  T         P+P P G    T 
Sbjct: 1931 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1990

Query: 1771 NNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKM 1830
              I  +           T      ++     I     V       G        Q P   
Sbjct: 1991 TPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQTPTTT 2037

Query: 1831 CLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTST 1890
             +     V    TP G   T TP T P T +   ++PT + +  Q + TTT +TT+TT T
Sbjct: 2038 PITTTTTVTPTPTPTG---TQTPTTTPITTT-TTVTPTPTPTGTQ-TPTTTPITTTTTVT 2092

Query: 1891 P-------QTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTST 1943
            P       QT TT   TT+TT  PT   T    T+T + +P +TT+    TP+P  T + 
Sbjct: 2093 PTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTVTPTPTPTGTQTP 2149

Query: 1944 ISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGP 2003
             + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT TT+  TT+TT   
Sbjct: 2150 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTT--- 2205

Query: 2004 GTTPSPVPT 2012
              TP+P PT
Sbjct: 2206 -VTPTPTPT 2213



 Score =  141 bits (355), Expect = 7e-33
 Identities = 163/590 (27%), Positives = 223/590 (37%), Gaps = 84/590 (14%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3716 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3775

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3776 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3835

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3836 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3889

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3890 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3942

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3943 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4002

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 4003 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 4055

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSR 1878
                  Q P    +     V    TP G   T TP T P T +   ++PT + +  Q + 
Sbjct: 4056 ------QTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTT-TTVTPTPTPTGTQ-TP 4104

Query: 1879 TTTLVTTSTTSTP-------QTSTTYAHTTSTTSAP------TARTTSAPTTRTTSASPA 1925
            TTT +TT+TT TP       QT TT   TT+TT  P      T   T+ P T TT+ +P 
Sbjct: 4105 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4164

Query: 1926 STTSGPGN-TPSPVPTTSTIS---APTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTS 1981
             T +G    T +P+ TT+T++    PT + T  PT ++T+     TTS P   +++  TS
Sbjct: 4165 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTS 4224

Query: 1982 STTSSPQTSTT------------------SAPTTSTTSGPGTTPSPVPTT 2013
             +TSSP T +T                  S PT  TT+  G T SP P+T
Sbjct: 4225 RSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPST 4274



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 1968 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2027

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2028 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2087

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2088 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2141

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2142 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2194

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2195 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2254

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2255 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2307

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2308 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2356

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2357 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2413

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2414 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2472

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2473 TTPITTTTT----VTPTPTPT 2489



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 1991 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2050

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2051 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2110

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2111 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2164

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2165 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2217

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2218 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2277

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2278 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2330

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2331 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2379

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2380 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2436

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2437 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2495

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2496 TTPITTTTT----VTPTPTPT 2512



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2014 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2073

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2074 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2133

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2134 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2187

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2188 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2240

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2241 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2300

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2301 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2353

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2354 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2402

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2403 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2459

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2460 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2518

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2519 TTPITTTTT----VTPTPTPT 2535



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2037 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2096

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2097 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2156

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2157 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2210

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2211 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2263

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2264 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2323

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2324 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2376

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2377 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2425

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2426 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2482

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2483 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2541

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2542 TTPITTTTT----VTPTPTPT 2558



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2060 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2119

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2120 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2179

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2180 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2233

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2234 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2286

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2287 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2346

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2347 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2399

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2400 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2448

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2449 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2505

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2506 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2564

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2565 TTPITTTTT----VTPTPTPT 2581



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2083 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2142

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2143 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2202

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2203 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2256

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2257 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2309

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2310 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2369

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2370 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2422

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2423 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2471

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2472 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2528

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2529 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2587

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2588 TTPITTTTT----VTPTPTPT 2604



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2106 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2165

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2166 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2225

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2226 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2279

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2280 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2332

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2333 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2392

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2393 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2445

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2446 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2494

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2495 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2551

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2552 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2610

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2611 TTPITTTTT----VTPTPTPT 2627



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2129 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2188

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2189 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2248

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2249 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2302

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2303 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2355

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2356 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2415

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2416 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2468

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2469 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2517

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2518 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2574

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2575 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2633

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2634 TTPITTTTT----VTPTPTPT 2650



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2152 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2211

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2212 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2271

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2272 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2325

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2326 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2378

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2379 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2438

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2439 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2491

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2492 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2540

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2541 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2597

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2598 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2656

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2657 TTPITTTTT----VTPTPTPT 2673



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2175 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2234

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2235 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2294

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2295 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2348

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2349 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2401

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2402 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2461

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2462 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2514

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2515 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2563

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2564 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2620

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2621 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2679

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2680 TTPITTTTT----VTPTPTPT 2696



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2198 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2257

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2258 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2317

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2318 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2371

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2372 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2424

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2425 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2484

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2485 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2537

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2538 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2586

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2587 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2643

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2644 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2702

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2703 TTPITTTTT----VTPTPTPT 2719



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2221 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2280

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2281 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2340

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2341 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2394

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2395 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2447

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2448 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2507

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2508 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2560

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2561 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2609

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2610 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2666

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2667 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2725

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2726 TTPITTTTT----VTPTPTPT 2742



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2244 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2303

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2304 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2363

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2364 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2417

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2418 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2470

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2471 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2530

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2531 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2583

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2584 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2632

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2633 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2689

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2690 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2748

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2749 TTPITTTTT----VTPTPTPT 2765



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2267 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2326

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2327 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2386

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2387 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2440

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2441 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2493

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2494 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2553

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2554 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2606

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2607 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2655

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2656 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2712

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2713 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2771

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2772 TTPITTTTT----VTPTPTPT 2788



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2290 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2349

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2409

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2410 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2463

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2464 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2516

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2517 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2576

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2577 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2629

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2630 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2678

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2679 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2735

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2736 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2794

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2795 TTPITTTTT----VTPTPTPT 2811



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2313 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2372

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2373 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2432

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2433 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2486

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2487 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2539

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2540 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2599

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2600 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2652

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2653 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2701

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2702 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2758

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2759 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2817

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2818 TTPITTTTT----VTPTPTPT 2834



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2336 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2395

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2396 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2455

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2456 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2509

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2510 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2562

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2563 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2622

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2623 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2675

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2676 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2724

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2725 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2781

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2782 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2840

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2841 TTPITTTTT----VTPTPTPT 2857



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2359 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2418

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2419 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2478

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2479 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2532

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2533 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2585

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2586 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2645

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2646 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2698

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2699 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2747

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2748 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2804

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2805 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2863

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2864 TTPITTTTT----VTPTPTPT 2880



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2382 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2441

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2442 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2501

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2502 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2555

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2556 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2608

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2609 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2668

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2669 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2721

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2722 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2770

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2771 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2827

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2828 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2886

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2887 TTPITTTTT----VTPTPTPT 2903



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2405 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2464

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2465 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2524

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2525 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2578

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2579 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2631

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2632 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2691

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2692 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2744

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2745 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2793

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2794 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2850

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2851 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2909

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2910 TTPITTTTT----VTPTPTPT 2926



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2428 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2487

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2488 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2547

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2548 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2601

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2602 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2654

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2655 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2714

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2715 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2767

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2768 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2816

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2817 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2873

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2874 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2932

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2933 TTPITTTTT----VTPTPTPT 2949



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2451 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2510

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2511 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2570

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2571 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2624

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2625 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2677

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2678 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2737

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2738 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2790

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2791 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2839

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2840 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2896

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2897 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2955

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2956 TTPITTTTT----VTPTPTPT 2972



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2474 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2533

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2534 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2593

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2594 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2647

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2648 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2700

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2701 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2760

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2761 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2813

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2814 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2862

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2863 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2919

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2920 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 2978

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 2979 TTPITTTTT----VTPTPTPT 2995



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2497 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2556

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2557 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2616

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2617 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2670

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2671 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2723

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2724 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2783

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2784 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2836

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2837 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2885

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2886 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2942

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2943 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3001

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3002 TTPITTTTT----VTPTPTPT 3018



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2520 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2579

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2580 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2639

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2640 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2693

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2694 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2746

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2747 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2806

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2807 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2859

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2860 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2908

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2909 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2965

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2966 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3024

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3025 TTPITTTTT----VTPTPTPT 3041



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2543 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2602

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2603 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2662

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2663 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2716

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2717 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2769

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2770 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2829

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2830 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2882

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2883 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2931

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2932 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 2988

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 2989 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3047

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3048 TTPITTTTT----VTPTPTPT 3064



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2566 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2625

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2626 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2685

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2686 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2739

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2740 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2792

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2793 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2852

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2853 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2905

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2906 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2954

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2955 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3011

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3012 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3070

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3071 TTPITTTTT----VTPTPTPT 3087



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2589 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2648

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2649 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2708

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2709 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2762

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2763 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2815

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2816 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2875

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2876 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2928

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2929 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 2977

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 2978 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3034

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3035 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3093

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3094 TTPITTTTT----VTPTPTPT 3110



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2671

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2672 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2731

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2732 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2785

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2786 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2838

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2839 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2898

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2899 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2951

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2952 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3000

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3001 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3057

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3058 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3116

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3117 TTPITTTTT----VTPTPTPT 3133



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2635 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2694

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2695 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2754

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2755 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2808

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2809 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2861

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2862 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2921

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2922 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2974

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2975 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3023

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3024 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3080

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3081 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3139

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3140 TTPITTTTT----VTPTPTPT 3156



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2658 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2717

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2718 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2777

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2778 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2831

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2832 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2884

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2885 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2944

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2945 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2997

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 2998 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3046

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3047 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3103

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3104 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3162

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3163 TTPITTTTT----VTPTPTPT 3179



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2681 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2740

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2741 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2800

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2801 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2854

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2855 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2907

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2908 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2967

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2968 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3020

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3021 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3069

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3070 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3126

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3127 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3185

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3186 TTPITTTTT----VTPTPTPT 3202



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2704 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2763

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2764 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2823

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2824 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2877

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2878 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2930

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2931 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2990

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 2991 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3043

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3044 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3092

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3093 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3149

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3150 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3208

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3209 TTPITTTTT----VTPTPTPT 3225



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2727 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2786

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2787 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2846

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2847 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2900

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2901 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2953

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2954 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3013

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3014 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3066

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3067 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3115

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3116 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3172

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3173 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3231

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3232 TTPITTTTT----VTPTPTPT 3248



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2750 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2809

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2810 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2869

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2870 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2923

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2924 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2976

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 2977 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3036

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3037 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3089

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3090 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3138

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3139 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3195

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3196 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3254

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3255 TTPITTTTT----VTPTPTPT 3271



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2773 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2832

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2833 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2892

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2893 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2946

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2947 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 2999

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3000 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3059

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3060 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3112

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3113 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3161

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3162 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3218

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3219 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3277

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3278 TTPITTTTT----VTPTPTPT 3294



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2796 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2855

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2856 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2915

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2916 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2969

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2970 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3022

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3023 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3082

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3083 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3135

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3136 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3184

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3185 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3241

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3242 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3300

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3301 TTPITTTTT----VTPTPTPT 3317



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2819 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2878

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2879 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2938

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2939 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2992

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 2993 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3045

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3046 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3105

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3106 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3158

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3159 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3207

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3208 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3264

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3265 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3323

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3324 TTPITTTTT----VTPTPTPT 3340



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2842 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2901

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2961

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2962 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3015

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3016 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3068

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3069 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3128

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3129 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3181

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3182 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3230

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3231 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3287

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3288 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3346

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3347 TTPITTTTT----VTPTPTPT 3363



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2865 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2924

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2925 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2984

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 2985 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3038

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3039 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3091

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3092 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3151

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3152 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3204

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3205 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3253

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3254 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3310

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3311 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3369

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3370 TTPITTTTT----VTPTPTPT 3386



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2888 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2947

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2948 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3007

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3008 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3061

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3062 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3114

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3115 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3174

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3175 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3227

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3228 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3276

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3277 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3333

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3334 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3392

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3393 TTPITTTTT----VTPTPTPT 3409



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2911 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2970

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2971 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3030

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3031 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3084

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3085 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3137

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3138 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3197

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3198 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3250

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3251 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3299

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3300 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3356

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3357 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3415

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3416 TTPITTTTT----VTPTPTPT 3432



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2993

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 2994 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3053

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3054 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3107

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3108 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3160

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3161 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3220

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3221 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3273

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3274 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3322

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3323 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3379

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3380 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3438

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3439 TTPITTTTT----VTPTPTPT 3455



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2957 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3016

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3017 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3076

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3077 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3130

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3131 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3183

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3184 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3243

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3244 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3296

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3297 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3345

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3346 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3402

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3403 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3461

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3462 TTPITTTTT----VTPTPTPT 3478



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 2980 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3039

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3040 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3099

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3100 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3153

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3154 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3206

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3207 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3266

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3267 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3319

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3320 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3368

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3369 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3425

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3426 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3484

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3485 TTPITTTTT----VTPTPTPT 3501



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3003 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3062

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3122

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3123 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3176

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3177 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3229

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3230 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3289

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3290 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3342

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3343 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3391

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3392 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3448

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3449 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3507

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3508 TTPITTTTT----VTPTPTPT 3524



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3026 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3085

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3086 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3145

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3146 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3199

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3200 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3252

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3253 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3312

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3313 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3365

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3366 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3414

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3415 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3471

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3472 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3530

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3531 TTPITTTTT----VTPTPTPT 3547



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3049 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3108

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3109 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3168

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3169 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3222

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3223 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3275

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3276 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3335

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3336 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3388

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3389 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3437

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3438 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3494

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3495 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3553

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3554 TTPITTTTT----VTPTPTPT 3570



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3072 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3131

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3132 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3191

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3192 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3245

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3246 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3298

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3299 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3358

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3359 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3411

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3412 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3460

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3461 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3517

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3518 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3576

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3577 TTPITTTTT----VTPTPTPT 3593



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3095 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3154

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3155 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3214

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3215 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3268

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3269 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3321

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3322 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3381

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3382 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3434

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3435 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3483

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3484 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3540

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3541 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3599

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3600 TTPITTTTT----VTPTPTPT 3616



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3118 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3177

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3178 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3237

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3238 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3291

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3292 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3344

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3345 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3404

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3405 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3457

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3458 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3506

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3507 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3563

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3564 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3622

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3623 TTPITTTTT----VTPTPTPT 3639



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3141 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3200

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3201 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3260

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3261 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3314

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3315 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3367

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3368 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3427

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3428 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3480

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3481 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3529

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3530 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3586

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3587 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3645

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3646 TTPITTTTT----VTPTPTPT 3662



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3164 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3223

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3224 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3283

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3284 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3337

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3338 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3390

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3391 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3450

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3451 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3503

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3504 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3552

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3553 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3609

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3610 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3668

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3669 TTPITTTTT----VTPTPTPT 3685



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3187 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3246

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3247 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3306

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3307 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3360

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3361 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3413

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3414 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3473

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3474 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3526

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3527 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3575

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3576 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3632

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3633 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3691

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3692 TTPITTTTT----VTPTPTPT 3708



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3210 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3269

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3270 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3329

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3330 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3383

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3384 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3436

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3437 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3496

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3497 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3549

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3550 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3598

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3599 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3655

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3656 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3714

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3715 TTPITTTTT----VTPTPTPT 3731



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3233 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3292

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3293 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3352

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3353 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3406

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3407 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3459

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3460 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3519

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3520 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3572

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3573 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3621

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3622 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3678

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3679 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3737

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3738 TTPITTTTT----VTPTPTPT 3754



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3256 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3315

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3316 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3375

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3376 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3429

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3430 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3482

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3483 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3542

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3543 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3595

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3596 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3644

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3645 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3701

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3702 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3760

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3761 TTPITTTTT----VTPTPTPT 3777



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3279 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3338

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3398

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3399 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3452

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3453 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3505

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3506 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3565

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3566 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3618

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3619 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3667

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3668 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3724

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3725 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3783

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3784 TTPITTTTT----VTPTPTPT 3800



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3302 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3361

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3362 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3421

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3422 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3475

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3476 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3528

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3529 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3588

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3589 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3641

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3642 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3690

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3691 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3747

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3748 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3806

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3807 TTPITTTTT----VTPTPTPT 3823



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3325 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3384

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3385 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3444

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3445 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3498

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3499 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3551

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3552 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3611

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3612 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3664

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3665 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3713

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3714 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3770

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3771 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3829

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3830 TTPITTTTT----VTPTPTPT 3846



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3348 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3407

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3408 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3467

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3468 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3521

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3522 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3574

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3575 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3634

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3635 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3687

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3688 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3736

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3737 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3793

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3794 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3852

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3853 TTPITTTTT----VTPTPTPT 3869



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3371 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3430

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3431 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3490

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3491 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3544

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3545 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3597

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3598 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3657

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3658 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3710

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3711 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3759

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3760 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3816

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3817 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3875

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3876 TTPITTTTT----VTPTPTPT 3892



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3394 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3453

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3513

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3514 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3567

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3568 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3620

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3621 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3680

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3681 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3733

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3734 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3782

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3783 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3839

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3840 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3898

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3899 TTPITTTTT----VTPTPTPT 3915



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3417 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3476

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3477 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3536

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3537 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3590

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3591 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3643

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3644 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3703

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3704 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3756

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3757 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3805

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3806 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3862

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3863 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3921

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3922 TTPITTTTT----VTPTPTPT 3938



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3440 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3499

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3500 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3559

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3560 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3613

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3614 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3666

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3667 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3726

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3727 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3779

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3780 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3828

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3829 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3885

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3886 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3944

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3945 TTPITTTTT----VTPTPTPT 3961



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3463 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3522

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3523 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3582

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3583 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3636

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3637 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3689

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3690 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3749

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3750 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3802

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3803 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3851

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3852 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3908

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3909 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3967

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3968 TTPITTTTT----VTPTPTPT 3984



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3486 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3545

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3546 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3605

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3606 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3659

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3660 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3712

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3713 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3772

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3773 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3825

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3826 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3874

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3875 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3931

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3932 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 3990

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 3991 TTPITTTTT----VTPTPTPT 4007



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3509 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3568

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3569 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3628

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3629 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3682

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3683 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3735

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3736 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3795

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3796 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3848

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3849 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3897

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3898 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3954

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3955 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 4013

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 4014 TTPITTTTT----VTPTPTPT 4030



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3532 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3591

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3592 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3651

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3652 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3705

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3706 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3758

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3759 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3818

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3819 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3871

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3872 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3920

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3921 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 3977

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 3978 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 4036

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 4037 TTPITTTTT----VTPTPTPT 4053



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3555 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3614

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3615 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3674

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3675 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3728

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3729 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3781

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3782 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3841

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3842 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3894

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3895 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3943

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3944 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 4000

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 4001 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 4059

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 4060 TTPITTTTT----VTPTPTPT 4076



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3578 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3637

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3697

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3698 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3751

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3752 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3804

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3805 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3864

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3865 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3917

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3918 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3966

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3967 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 4023

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 4024 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 4082

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 4083 TTPITTTTT----VTPTPTPT 4099



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3601 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3660

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3661 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3720

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3721 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3774

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3775 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3827

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3828 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3887

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3888 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3940

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3941 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 3989

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 3990 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 4046

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 4047 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 4105

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 4106 TTPITTTTT----VTPTPTPT 4122



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3624 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3683

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3684 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3743

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3744 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3797

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3798 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3850

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3851 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3910

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3911 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3963

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3964 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 4012

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 4013 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 4069

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 4070 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 4128

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 4129 TTPITTTTT----VTPTPTPT 4145



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3647 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3706

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3707 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3766

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3767 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3820

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3821 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3873

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3874 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3933

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3934 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 3986

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 3987 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 4035

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 4036 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 4092

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 4093 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 4151

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 4152 TTPITTTTT----VTPTPTPT 4168



 Score =  139 bits (350), Expect = 3e-32
 Identities = 154/561 (27%), Positives = 215/561 (38%), Gaps = 64/561 (11%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3670 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3729

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3730 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3789

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3790 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3843

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3844 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3896

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3897 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3956

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 3957 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 4009

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGC------PVTSTPVTAPS-TPSGRAISPTQST 1871
                  Q P    +     V    TP G       P+T+T    P+ TP+G     TQ+ 
Sbjct: 4010 ------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-----TQTP 4058

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            ++   + TTT+  T T +  QT TT   TT+TT  PT   T    T+T + +P +TT+  
Sbjct: 4059 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTV 4115

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST 1991
              TP+P  T +  + P T+ T+   T T +   + TT+  TT+TT  PT + T + QT T
Sbjct: 4116 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPT 4174

Query: 1992 TSAPTTSTTSGPGTTPSPVPT 2012
            T+  TT+TT     TP+P PT
Sbjct: 4175 TTPITTTTT----VTPTPTPT 4191



 Score =  137 bits (346), Expect = 8e-32
 Identities = 164/574 (28%), Positives = 219/574 (38%), Gaps = 70/574 (12%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3762 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3821

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3822 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3881

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3882 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3935

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3936 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 3988

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 3989 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4048

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 4049 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 4101

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSR 1878
                  Q P    +     V    TP G   T TP T P T +   ++PT + +  Q + 
Sbjct: 4102 ------QTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTT-TTVTPTPTPTGTQ-TP 4150

Query: 1879 TTTLVTTSTTSTP-------QTSTTYAHTTSTTSAPTARTT---SAPTTRTTSASPAS-T 1927
            TTT +TT+TT TP       QT TT   TT+TT  PT   T   + P T T++A  A  T
Sbjct: 4151 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELT 4210

Query: 1928 TSGPGNTPSPVPTTSTISAPTTSITSA-----PTTSTTSAPTSSTTSAPTTST---TSAP 1979
            TS P    S   T+ + S+P T  T+      P    TS    ST +APTT++   T +P
Sbjct: 4211 TSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSP 4270

Query: 1980 TSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
              STT+SP  + T   TT ++S P  TPS V TT
Sbjct: 4271 PPSTTTSPPGTPTRGTTTGSSSAP--TPSTVQTT 4302



 Score =  131 bits (329), Expect = 8e-30
 Identities = 80/186 (43%), Positives = 104/186 (55%), Gaps = 16/186 (8%)

Query: 1843 TPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTT-------STTSTPQTST 1895
            TP      S P T PS P+     PT +T++   + T +  TT       STT+ P T+T
Sbjct: 1463 TPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTT 1522

Query: 1896 TYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAP 1955
                TT+TT+ P   T S PTT   +   ++TT  P  TPSP PTT+T   PTT+  S P
Sbjct: 1523 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT-PSPP 1581

Query: 1956 TTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTS--------TTSGPGTTP 2007
            TT+T S PT +TT+ P T+T S PT++TT+ P T+T S PTT+        TT  P TTP
Sbjct: 1582 TTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP 1641

Query: 2008 SPVPTT 2013
            SP PTT
Sbjct: 1642 SPPPTT 1647



 Score =  129 bits (325), Expect = 2e-29
 Identities = 77/178 (43%), Positives = 103/178 (57%), Gaps = 9/178 (5%)

Query: 1844 PRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST 1903
            P     T  P T PS P+   I+P  ST++   + T +  TT+TT+ P T+T    TT+ 
Sbjct: 1487 PTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1546

Query: 1904 TSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAP 1963
             + PT+ TT  PTT  +     +TT  P  TPSP PTT+T S PT + T+ P T+T S P
Sbjct: 1547 ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSP-PTTTTPSPPTITTTTPPPTTTPSPP 1605

Query: 1964 TSSTTSAPTTSTTSAPTS-------STTSSPQTSTTSAP-TTSTTSGPGTTPSPVPTT 2013
            T++TT+ P T+T S PT+       STT+ P T+T S P TT+TT  P TTPSP  TT
Sbjct: 1606 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTT 1663



 Score =  127 bits (319), Expect = 1e-28
 Identities = 130/523 (24%), Positives = 202/523 (38%), Gaps = 63/523 (12%)

Query: 425  CQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSA--FTVLAELRRCGLTD 482
            C    C   C+  G  H+ TFDG  Y+  G+C+YVL +    S   F V  +   C   D
Sbjct: 4472 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 4531

Query: 483  SETCLKSVTLSLDG----VQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQ 538
              +C +++ +  +     ++TV ++    +V +N+    LP     + +++    +++  
Sbjct: 4532 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 4591

Query: 539  TSLGLQLNLQ-LVPTMQL-FMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVV----EAT 592
              LG+ ++   L  +++L + +     +GQ CG C N  S   DD    SG +    EA 
Sbjct: 4592 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQ-CGTCTNTTS---DDCILPSGEIVSNCEAA 4647

Query: 593  AAAFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQH-------WCSQLTDADGPFGRCH 645
            A  +     ++  CP+  ++ + P        K   H        C  + D+   F +CH
Sbjct: 4648 ADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDS--LFAQCH 4705

Query: 646  AAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCP 705
            A V P  YY  C+FD+C    S    CA+L +Y   CA + + L  WR+      +  CP
Sbjct: 4706 ALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALCAQQNICL-DWRNHTHGACLVECP 4763

Query: 706  KSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYH 765
                Y       +PTC+S S          + V+GC CP+GT     G  V    C C  
Sbjct: 4764 SHREYQACGPAEEPTCKSSSSQQNNT----VLVEGCFCPEGTMNYAPGFDVCVKTCGCVG 4819

Query: 766  RGSMIPN--GESVHDSGAICTCTHGKLSCI-----GGQAPAPVCAAPMVFFDCRNATPGD 818
              + +P   GE        C C  G    I       Q P   C     +       P D
Sbjct: 4820 PDN-VPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYL-ATEVNPAD 4877

Query: 819  TGAGCQKSCHTLDMTCYSPQC-VPGCVCPDGLVADGE---GGCITAEDCP----CVHNEA 870
            T       C+     C +  C     VCP G     +   G C     C     CVH  A
Sbjct: 4878 T------CCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA 4931

Query: 871  SYRAGQTIRVG-CNTCTCDSR--------MWRCTDDPCLATCA 904
             Y+ G  +    C  C C  +        +  CT  PC  +C+
Sbjct: 4932 EYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 4974



 Score =  127 bits (318), Expect = 1e-28
 Identities = 77/181 (42%), Positives = 100/181 (55%), Gaps = 11/181 (6%)

Query: 1843 TPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTS 1902
            TP     T  P T PS P     +P  +T+    + TT    T TT+TP  +TT +  T+
Sbjct: 1548 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT 1607

Query: 1903 TTSAPTARTTSAPTTRTTSASPASTTS-GPGNTPSPVPTTSTISAPTTSITSAPTTSTTS 1961
            TT+ P   TT +P T T    P STT+  P  TPSP PTT+T   PTT+  S PTT+T S
Sbjct: 1608 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT-PSPPTTTTPS 1666

Query: 1962 APTSSTTSAPTTSTTSAP---------TSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPT 2012
             P ++TT+ P T+T S+P         T+ TT SP T+ +S  TT+TT    TTPSP PT
Sbjct: 1667 PPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPT 1726

Query: 2013 T 2013
            T
Sbjct: 1727 T 1727



 Score =  126 bits (317), Expect = 2e-28
 Identities = 72/171 (42%), Positives = 100/171 (58%), Gaps = 2/171 (1%)

Query: 1844 PRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST 1903
            P     T  P T PS P+   I+P  ST++   + TT     +TT+TP  +TT +  T+T
Sbjct: 1526 PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT-TTPSPPPTTTTTPPPTTTPSPPTTT 1584

Query: 1904 TSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAP 1963
            T +P   TT+ P   TT + P +TT+ P  T +P P T+T   P TS T+ P T+T S P
Sbjct: 1585 TPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP 1644

Query: 1964 TSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGP-GTTPSPVPTT 2013
             ++TT+ P T+T S PT++T S P T+TT+ P T+T S P  TTPSP  TT
Sbjct: 1645 PTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTT 1695



 Score =  126 bits (317), Expect = 2e-28
 Identities = 162/582 (27%), Positives = 221/582 (37%), Gaps = 82/582 (14%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3785 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3844

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3845 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3904

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3905 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3958

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 3959 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 4011

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 4012 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4071

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 4072 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 4124

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSR 1878
                  Q P    +     V    TP G   T TP T P T +   ++PT + +  Q + 
Sbjct: 4125 ------QTPTTTPITTTTTVTPTPTPTG---TQTPTTTPITTT-TTVTPTPTPTGTQ-TP 4173

Query: 1879 TTTLVTTSTTSTPQTSTTYAHT---TSTTSAPTAR-TTSAP--------TTRTTSASPAS 1926
            TTT +TT+TT TP  + T   T   T T++AP A  TTS P        T+R+TS+    
Sbjct: 4174 TTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTE 4233

Query: 1927 TTSGPGNTPSPVPTTSTI-----SAPTTSI---TSAPTTSTTSAPTSSTTSAPTTSTTSA 1978
            +T+     P  +  TST      +APTT+    T +P  STT++P  + T   TT ++SA
Sbjct: 4234 STTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA 4293

Query: 1979 PTSSTTSSPQTSTTSA----------PTTSTTSGPGTTPSPV 2010
            PT ST    QT+TTSA          P+   T+G    PS V
Sbjct: 4294 PTPSTV---QTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSV 4332



 Score =  125 bits (314), Expect = 4e-28
 Identities = 75/183 (40%), Positives = 100/183 (54%), Gaps = 12/183 (6%)

Query: 1843 TPRGCPVTST---PVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAH 1899
            TP   P T+T   P T PS P+    SP   T++     TT    T+TT+TP  +TT + 
Sbjct: 1561 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP 1620

Query: 1900 TTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTST 1959
             T+T   P   TT+ P T T S  P +TT+ P  T    PTT+T S P T+ T+ P T+T
Sbjct: 1621 PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTT 1680

Query: 1960 TSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTS---------APTTSTTSGPGTTPSPV 2010
             S+P ++T S PTT+ T+   ++T SSP T+TT+          PTT TT  P TTPSP 
Sbjct: 1681 PSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPP 1740

Query: 2011 PTT 2013
             TT
Sbjct: 1741 TTT 1743



 Score =  122 bits (307), Expect = 3e-27
 Identities = 72/172 (41%), Positives = 95/172 (55%), Gaps = 2/172 (1%)

Query: 1843 TPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTS 1902
            TP     T  P T PS P+    +P  +T+    + T     TSTT+ P T+T     T+
Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1568

Query: 1903 TTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSA 1962
            TT+ P   T S PTT T S    +TT+ P  T    PTT+T + P T+  S PTT+  + 
Sbjct: 1569 TTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1628

Query: 1963 PTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGP-GTTPSPVPTT 2013
            PTS+TT  PTT T S P ++TT+ P T+T S PTT+T S P  TT +P PTT
Sbjct: 1629 PTSTTTLPPTT-TPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTT 1679



 Score =  117 bits (292), Expect = 1e-25
 Identities = 73/171 (42%), Positives = 94/171 (54%), Gaps = 10/171 (5%)

Query: 1844 PRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST 1903
            P     T  P T PS P+   I+P  ST        TTL  T+T S P T+TT    T+T
Sbjct: 1605 PTTTTTTPPPTTTPSPPTTTPITPPTST--------TTLPPTTTPSPPPTTTTTPPPTTT 1656

Query: 1904 TSAPTARTTSAPTTRTTSASPASTTSGP-GNTPSPVPTTSTISAPTTSITSAPTTSTTSA 1962
             S PT  T S P T TT+  P +T S P   TPSP  TT T  +PTT+ +S  TT+TT +
Sbjct: 1657 PSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPS 1716

Query: 1963 PTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
             T++ +  PTT TT +PT +T S P T+ T+ P T+T+S   TTP P   T
Sbjct: 1717 STTTPSPPPTTMTTPSPT-TTPSPPTTTMTTLPPTTTSSPLTTTPLPPSIT 1766



 Score =  114 bits (286), Expect = 7e-25
 Identities = 69/175 (39%), Positives = 98/175 (56%), Gaps = 4/175 (2%)

Query: 1843 TPRGCPVTST---PVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAH 1899
            TP    +T+T   P T PS P+    +P  +T+    + T     TSTT+ P T+T    
Sbjct: 1585 TPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP 1644

Query: 1900 TTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITS-APTTS 1958
             T+TT+ P   T S PTT T S    +TT+ P  T    P T+T S PTT++T+ +PTT+
Sbjct: 1645 PTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTT 1704

Query: 1959 TTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
             +S  T++TT + TT+ +  PT+ TT SP T+ +   TT TT  P TT SP+ TT
Sbjct: 1705 PSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTT 1759



 Score =  111 bits (278), Expect = 6e-24
 Identities = 113/414 (27%), Positives = 167/414 (40%), Gaps = 63/414 (15%)

Query: 894  CTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPC 953
            C    C   C  +GD HY+TFDG  YS+ G+C Y LV+        + D+F V  +N  C
Sbjct: 4472 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE----ISPSVDNFGVYIDNYHC 4527

Query: 954  GTTG-TTCSKAIKIFLGGFE--LKLSH---GKVEVIGTDESQEVPY-----TIRQMGIYL 1002
                  +C + + +     E  +K  H    +V+V    ++  +PY      + Q GI  
Sbjct: 4528 DPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINY 4587

Query: 1003 VVDTDIGLVLLWDKKTSIFINLS-PEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEF 1061
            VVD     VL+     S  + L    F     G CG   +   +D    S  +V +    
Sbjct: 4588 VVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAA 4647

Query: 1062 GNSWKLS----PSCP-DALAPKDPCT-------ANPFRKSWAQKQCSILHGPTFAACHAH 1109
             + W ++    P CP  +   K P           P +       C ++    FA CHA 
Sbjct: 4648 ADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHAL 4707

Query: 1110 VEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWR--TPSICPLFCDY 1167
            V P  YY+ACV D+C    G   E  C ++ AYA  C +  +C+ WR  T   C + C  
Sbjct: 4708 VPPQHYYDACVFDSCFM-PGSSLE--CASLQAYAALCAQQNICLDWRNHTHGACLVECPS 4764

Query: 1168 YNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPP----EAPIFDEDKMQ 1223
            +         YQ CG     TC++        V  +EGC+  CP      AP FD     
Sbjct: 4765 HR-------EYQACGPAEEPTCKSSSSQQNNTVL-VEGCF--CPEGTMNYAPGFD----V 4810

Query: 1224 CVATCPT--PPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEAC 1275
            CV TC    P   PR    G+ +        + +C++C+C E G     + + C
Sbjct: 4811 CVKTCGCVGPDNVPR--EFGEHF--------EFDCKNCVCLEGGSGIICQPKRC 4854



 Score =  108 bits (271), Expect = 4e-23
 Identities = 110/402 (27%), Positives = 165/402 (41%), Gaps = 49/402 (12%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRR-----SQESAAPTLSR 135
            C+ WG  HY TFDG  + + G C YV  E    + ++F + +       + + + P    
Sbjct: 4481 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 4540

Query: 136  VLMKVDGVVIQLT-----KGSVLVNGHPVLLPFSQSGVLIQQSS-SYTKVEARLGLVLMW 189
            V  +   V+I+       +  V VN   V LP+ + G+ + QS  +Y      LG+++ +
Sbjct: 4541 VRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSY 4600

Query: 190  NHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKM-DDP---- 244
            N     +     ++ N T G CG          +L     ++  E    Q + +DP    
Sbjct: 4601 NGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPH 4660

Query: 245  -------TEQCQDPVP-----EPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACR 292
                   T++    VP      P ++C T   +C+ L+   LF+ C ALV    Y +AC 
Sbjct: 4661 CPHSSSTTKRPAVTVPGGGKTTPHKDC-TPSPLCQ-LIKDSLFAQCHALVPPQHYYDACV 4718

Query: 293  QDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDF--CPQKCPNNMQYHECRSP 350
             D CF   + L    C +L  Y+  C     +  DWR      C  +CP++ +Y  C   
Sbjct: 4719 FDSCFMPGSSL---ECASLQAYAALCAQQN-ICLDWRNHTHGACLVECPSHREYQACGPA 4774

Query: 351  CADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP---GA 407
               TC +   S+      V GCFCPEGT+    G   C  V  C CV  G    P   G 
Sbjct: 4775 EEPTCKSSS-SQQNNTVLVEGCFCPEGTMNYAPGFDVC--VKTCGCV--GPDNVPREFGE 4829

Query: 408  TYSTDCTNCTC--SGGRWSCQEVPC---PGTCSVLGGAHFST 444
             +  DC NC C   G    CQ   C   P T  V  G + +T
Sbjct: 4830 HFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLAT 4871



 Score =  104 bits (260), Expect = 8e-22
 Identities = 150/581 (25%), Positives = 205/581 (35%), Gaps = 71/581 (12%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRASGSSAPSST--PGTVSLSTARTTPAPGT 1529
            TP+  +T+ +P  T     TP TT  TT T  + +  P+ T  P T  ++T  T     T
Sbjct: 3854 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3913

Query: 1530 ATSVKKTFSTP-----SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584
             T  +   +TP     +  P P  + +   TTTP T+  +  PT T   T +      T 
Sbjct: 3914 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3973

Query: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICS 1644
            T  +    P P   G    T   +     T   +P       ++   TP+          
Sbjct: 3974 TTTVT---PTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4027

Query: 1645 HTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQT 1701
               G       Q P   PI     +      T       T P  T  T  PTP PTG QT
Sbjct: 4028 TPTG------TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 4080

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             TT      +  T  PT T    PT T +T  T  TP    T    P  T         P
Sbjct: 4081 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4140

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +           T      ++     I     V       G  
Sbjct: 4141 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 4193

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPT---------Q 1869
                 Q GP        +  L    P   P +STP T+ ST S    S T         +
Sbjct: 4194 -----QTGPPTHTSTAPIAELTTSNPP--PESSTPQTSRSTSSPLTESTTLLSTLPPAIE 4246

Query: 1870 STSSWQKSRTTTLVTTST--TSTPQTSTTYAHTTSTTSAPTARTTSAPT---TRTTSASP 1924
             TS+   S  T   TTS   T +P  STT +   + T   T  ++SAPT    +TT+ S 
Sbjct: 4247 MTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSA 4306

Query: 1925 ASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAP-----------TSSTTSAPTT 1973
             + T  P +TPS + TT     P++ +       T  AP           T    +   +
Sbjct: 4307 WTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLS 4366

Query: 1974 STTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPS-PVPTT 2013
             T      S  S+P  + T + +T T S P +TPS P P T
Sbjct: 4367 CTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGT 4407



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 70/305 (22%), Positives = 99/305 (32%), Gaps = 85/305 (27%)

Query: 1322 TPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPP 1381
            TP P  T + +T P+  ++T TP+  P+   TGP     PT   T+P   L T++   PP
Sbjct: 4164 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGP-----PTHTSTAPIAELTTSN---PP 4215

Query: 1382 VCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLRA 1441
                            P   T      T   L      +   P ++E  +   P  P   
Sbjct: 4216 ----------------PESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAP 4259

Query: 1442 L----GQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSSSPAQTTPPTTSK 1497
                 G  +   P    +                     TP   +T+ S +  TP T   
Sbjct: 4260 TTTSGGHTLSPPPSTTTSPPG------------------TPTRGTTTGSSSAPTPSTVQT 4301

Query: 1498 TTETRASGSSAPSSTPGTVSLSTARTTP--------------APGTAT------------ 1531
            TT +  + +  P STP  +  +  R  P              APG               
Sbjct: 4302 TTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFV 4361

Query: 1532 --SVKKTF--------STPSPPPVP--ATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQ 1579
              S+  T         STPSP P P  +T T S  ++TP      +KP    P      Q
Sbjct: 4362 NCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPEC-PDFDPPRQ 4420

Query: 1580 ELCTW 1584
            E  TW
Sbjct: 4421 ENETW 4425



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 30/74 (40%), Positives = 36/74 (48%), Gaps = 8/74 (10%)

Query: 1317 PCSPTTPVPPTTFSFSTPPLVVSS--THTPSNGPSSAHTGPPS---SAWPTTAGTSPRTR 1371
            P   TTP PPTT + + PP    S  T TP   P+S  T PP+   S  PTT  T P T 
Sbjct: 1596 PPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT 1655

Query: 1372 L---PTASASLPPV 1382
                PT +   PP+
Sbjct: 1656 TPSPPTTTTPSPPI 1669



 Score = 40.8 bits (94), Expect = 0.014
 Identities = 37/124 (29%), Positives = 47/124 (37%), Gaps = 19/124 (15%)

Query: 331  PDFCPQK----CPNNMQYHECRSPCADTCSNQEHSRACEDHCVAG-CFCPEGTVLDDIGQ 385
            P  C QK    C  +  Y       ADTC N    +     C      CP G  +     
Sbjct: 4851 PKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMV 4910

Query: 386  TG-CVPV----SKCACVYNGAAYAPGA-TYSTDCTNCTCSG--------GRWSCQEVPCP 431
             G C P     SK  CV+  A Y PG+  YS+ C +C C+            +C  VPC 
Sbjct: 4911 PGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCN 4970

Query: 432  GTCS 435
             +CS
Sbjct: 4971 TSCS 4974



 Score = 40.4 bits (93), Expect = 0.018
 Identities = 56/197 (28%), Positives = 72/197 (36%), Gaps = 39/197 (19%)

Query: 1321 TTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLP 1380
            T+  PP+T    T P   S  HT S  PS+  T PP +  PT   T+  +  PT      
Sbjct: 4248 TSTAPPST---PTAPTTTSGGHTLSPPPSTT-TSPPGT--PTRGTTTGSSSAPT------ 4295

Query: 1381 PVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLR 1440
            P   +    S W     P          T   +R  G R   S   + C   D    P  
Sbjct: 4296 PSTVQTTTTSAWTPTPTP--------LSTPSIIRTTGLRPYPSSVLICCVLNDTYYAP-- 4345

Query: 1441 ALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSSSPAQTTP-PTTSKTT 1499
              G+ V  +   G TC            Y +       L     S P+  +P PT SK+T
Sbjct: 4346 --GEEVY-NGTYGDTC------------YFVNCSLSCTLEFYNWSCPSTPSPTPTPSKST 4390

Query: 1500 ETRASGSSAPSS-TPGT 1515
             T +  SS PS  TPGT
Sbjct: 4391 PTPSKPSSTPSKPTPGT 4407



 Score = 36.2 bits (82), Expect = 0.33
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 3/67 (4%)

Query: 1315 VYPCSPTTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPT 1374
            + P + TT +PPTT    +PP   ++T  P+  PS   T  PS    TT  T P T  P+
Sbjct: 1626 ITPPTSTTTLPPTTTP--SPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT-TPPPTTTPS 1682

Query: 1375 ASASLPP 1381
            +  +  P
Sbjct: 1683 SPITTTP 1689



 Score = 33.1 bits (74), Expect = 2.8
 Identities = 30/92 (32%), Positives = 38/92 (41%), Gaps = 18/92 (19%)

Query: 1277 CTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPL 1336
            C  N   + PG+ +Y+ T G   C    C  + T+E   + C  T    PT  S STP  
Sbjct: 4336 CVLNDTYYAPGEEVYNGTYGDT-CYFVNCSLSCTLEFYNWSCPSTPSPTPTP-SKSTP-- 4391

Query: 1337 VVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSP 1368
                  TPS  PSS  + P       T GT P
Sbjct: 4392 ------TPSK-PSSTPSKP-------TPGTKP 4409



 Score = 32.3 bits (72), Expect = 4.8
 Identities = 36/145 (24%), Positives = 55/145 (37%), Gaps = 14/145 (9%)

Query: 1245 RPGAVVPSDKNCQSCLCTERGVECT--YKAEACVCTYNGQRFHPGDVIYHTTDGTGGCIS 1302
            +PG V+P       CL  E  V+C         + T   +   P      TT  T   ++
Sbjct: 1856 KPGGVIPM----AFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTT---VT 1908

Query: 1303 ARCGANGTIERRVYPCSPTTPVPPT-----TFSFSTPPLVVSSTHTPSNGPSSAHTGPPS 1357
                  GT      P + TT V PT     T + +T P+  ++T TP+  P+   T   +
Sbjct: 1909 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1968

Query: 1358 SAWPTTAGTSPRTRLPTASASLPPV 1382
                TT  T   T   T + +  P+
Sbjct: 1969 PITTTTTVTPTPTPTGTQTPTTTPI 1993



 Score = 32.3 bits (72), Expect = 4.8
 Identities = 53/258 (20%), Positives = 79/258 (30%), Gaps = 26/258 (10%)

Query: 699  KPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQA 758
            KP+T C +  TY         TC +++     C+         +CP G   +   K V  
Sbjct: 4857 KPVTHCVEDGTYLATEVNPADTCCNITV--CKCNTSLCKEKPSVCPLG--FEVKSKMVPG 4912

Query: 759  SNCP---------CYHRGSMIPNGESVHDSGAI-CTCT----HGKLSCIGGQAPAPVCAA 804
              CP         C H  +    G  V+ S    C CT    +  L  +      P   +
Sbjct: 4913 RCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTS 4972

Query: 805  PMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCP 864
                F+   A PG+    C K C         P      + P    +D +  C T   C 
Sbjct: 4973 CSPGFELMEA-PGE----CCKKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNC-TFFSCV 5026

Query: 865  CVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHY--LTFDGQSYSFN 922
             +HN+             +   C         + C  TC    +      T    +    
Sbjct: 5027 KIHNQLISSVSNITCPNFDASICIPGSITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSY 5086

Query: 923  GDCEYTLVQNHCGGKDST 940
              C  T++ NHC G   T
Sbjct: 5087 AGCTKTVLMNHCSGSCGT 5104


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 1091 bits (2822), Expect = 0.0
 Identities = 654/1715 (38%), Positives = 865/1715 (50%), Gaps = 210/1715 (12%)

Query: 346  ECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP 405
            E  + C D    + + RAC+      C CP G                C C       + 
Sbjct: 232  EAFADCQDLVPLEPYLRACQQD---RCRCPGGDT--------------CVC-------ST 267

Query: 406  GATYSTDCTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCD 465
             A +S  C++     G W         T +V  GA  +      Y   G         C 
Sbjct: 268  VAEFSRQCSHAGGRPGNWRT------ATSAVSPGASKTCPGNLVYLESGS---PCMDTCS 318

Query: 466  SSAFTVLAELRR-----CGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPI 520
                + L E  R     C         K+V L  D  + VVV K+ G V LN++   LP 
Sbjct: 319  HLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPH 378

Query: 521  SAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQAD 580
              A+ ++FRPS++ I+   ++G++L +QL P MQLF+ L    +GQ  GLCGNFN ++ D
Sbjct: 379  VTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGD 438

Query: 581  DFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGP 640
            DF+T SG+VEAT A F NT+K Q++C +  +  +DPCSL++E+  YA+HWCS L   + P
Sbjct: 439  DFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHWCSLLKKTETP 498

Query: 641  FGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKP 700
            FGRCH+AV P  YY  C +DTCNC+ +EDCLCAALSSY  AC AKGV L GWR+ VC K 
Sbjct: 499  FGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKD 558

Query: 701  MTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASN 760
            + +CP S  + Y+++TCQ TCRSLSE D  C  GF PVDGC CP  TFLD+ G+CV  + 
Sbjct: 559  VGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAK 618

Query: 761  CPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTG 820
            C CYHRG  +  G+ V      C C  G+L C   +     C AP +  DC N T   T 
Sbjct: 619  CSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATS 678

Query: 821  AGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRV 880
                 SC TL    Y  +CV GCVCPDGL+ DG GGC+  ++CPCVHN   Y +G  I+V
Sbjct: 679  KPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKV 738

Query: 881  GCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDST 940
             CNTCTC    W CT   C  TC++YG GHY+TFDG+ Y F+G C Y  VQ++C G++S+
Sbjct: 739  DCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYC-GQNSS 797

Query: 941  QDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGI 1000
              SF ++TENVPCGTTG TCSKAIKIF+G  ELKL      VI  DE   V YT R++G 
Sbjct: 798  LGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQ 857

Query: 1001 YLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLE 1060
            YLVV++  G++++WDK+T++FI L+P +KG VCGLCGNFD  + NDF TR   VV   L+
Sbjct: 858  YLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELD 917

Query: 1061 FGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACV 1120
            FGNSWK +P+CPD     +PC+ NP R+SWA+KQCSIL    F+ CH+ V+P  +YEACV
Sbjct: 918  FGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACV 977

Query: 1121 NDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWHYQP 1180
            +D+C+CD+GGDCECFC+AVA+YAQ C + G CV WRTP +CP+FCDYYNP  +CEWHY+P
Sbjct: 978  HDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEP 1037

Query: 1181 CGVPCLRTCRNPRG-DCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHV 1239
            CG     TCR   G      V  LEGCYP+CP + PI++ED  +CV           C+V
Sbjct: 1038 CGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKC-----GCYV 1092

Query: 1240 HGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYNGQRFHPGDVIYHTTDGTGG 1299
                Y PGA VP+++ C+SC+CT         +   VC     R   G ++  T DG   
Sbjct: 1093 EDTHYPPGASVPTEETCKSCVCT--------NSSQVVC-----RPEEGKILNQTQDG-AF 1138

Query: 1300 CISARCGANGTIERRVYPCSPTT-PVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSS 1358
            C    CG NGT+E+    CS TT P   TTF+  T P                       
Sbjct: 1139 CYWEICGPNGTVEKHFNICSITTRPSTLTTFTTITLPTT--------------------- 1177

Query: 1359 AWPTTAGTSPRTRLPTASASL---PPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRA 1415
              PTT  T+  T  PT+S  L   P +C   CLWS W++   P  G+D GD +T +    
Sbjct: 1178 --PTTFTTTTTTTTPTSSTVLSTTPKLC---CLWSDWINEDHPSSGSDDGDRETFDG--- 1229

Query: 1416 HGYRVCESPRSVECRAEDAPGVPLRALGQRVQ--CSPDVGLTCRNREQASG------LCY 1467
                VC +P  +ECR+   P + L  LGQ+VQ  C   VGL C+N +Q  G       C 
Sbjct: 1230 ----VCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQKPGGVIPMAFCL 1285

Query: 1468 NYQIRVQCC----TPLACSTSSSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTART 1523
            NY+I VQCC     P   +T+++   T  P T+ TT T       P+ TP     ST  T
Sbjct: 1286 NYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVT-------PTPTP----TSTQST 1334

Query: 1524 TPAPGTATSVKKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCT 1583
            TP P T T    T  TP+P P    + ++   TT  T   +  PT T+  T++ +    T
Sbjct: 1335 TPTPITTT----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1390

Query: 1584 WTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVIC 1643
             T       P P   G    T   +     T   +P       ++   TP+         
Sbjct: 1391 VT-------PTPTPTGTQTPTSTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPT 1440

Query: 1644 SHTEGLICLNKNQLP-PICYNYEIRIQCCETVNVCRDITRPPKTVATT-RPTPHPTGAQT 1701
                G       Q P P        +    T    +  T  P T  TT  PTP PTG QT
Sbjct: 1441 PTPTG------TQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 1494

Query: 1702 QTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFP 1758
             T       +  T  PT T    PT+T +T  T  TP    T    P  T         P
Sbjct: 1495 PTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTP 1554

Query: 1759 SPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLV 1818
            +P P G    T   I  +                               V       G  
Sbjct: 1555 TPTPTGTQTPTTTPITTT-----------------------------TTVTPTPTPTG-- 1583

Query: 1819 CRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTS-------TPVTAPSTPSGRAISPTQST 1871
                  Q P  + +     +    TP     T+       T VTA  TP+G     TQ+ 
Sbjct: 1584 -----TQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTG-----TQTP 1633

Query: 1872 SSWQKSRTTTLV-----TTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPAS 1926
            +    S TTT+      TT +T  P  ++T      TTS P   +++  T+R+TS+    
Sbjct: 1634 TMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTE 1693

Query: 1927 TTSGPGNTPSPVPTTSTI-----SAPTTSI---TSAPTTSTTSAPTSSTTSAPTTSTTSA 1978
            +T+     P  +  TST      +APTT+    T +P  STT++P  + T   TT ++SA
Sbjct: 1694 STTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA 1753

Query: 1979 PTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
            PT ST    QT+TTSA T + T  P +TPS + TT
Sbjct: 1754 PTPSTV---QTTTTSAWTPTPT--PLSTPSIIRTT 1783



 Score =  313 bits (803), Expect = 8e-85
 Identities = 155/320 (48%), Positives = 202/320 (63%), Gaps = 12/320 (3%)

Query: 70  RASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRS--QE 127
           R  N  HN  VCSTWG+FHYKTFDGDVFRFPGLC+Y F+  C  +Y++F + L+R   Q 
Sbjct: 28  RTRNHGHN--VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQA 85

Query: 128 SAAPTLSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVL 187
            A   +  +L+ +    I LT+   ++NG  V  P    G+LI++S +YTKV +R GL L
Sbjct: 86  EAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTL 145

Query: 188 MWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDDPTEQ 247
           MWN +D+L+LELDTK+ N TCGLCGD+NG+   SE LS     +P+EFGN+QK++ P   
Sbjct: 146 MWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVV 205

Query: 248 CQDPVPE-PPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSC 306
           C+DP  E  P +CS     CE LL  + F+ C  LV +  YL AC+QD C C   D  +C
Sbjct: 206 CEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGD--TC 263

Query: 307 VCHTLAEYSRQCTHAGGLPQDWRGPDF-----CPQKCPNNMQYHECRSPCADTCSNQEHS 361
           VC T+AE+SRQC+HAGG P +WR           + CP N+ Y E  SPC DTCS+ E S
Sbjct: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323

Query: 362 RACEDHCVAGCFCPEGTVLD 381
             CE+H + GCFCPEG   D
Sbjct: 324 SLCEEHRMDGCFCPEGAQAD 343



 Score =  135 bits (341), Expect = 3e-31
 Identities = 122/432 (28%), Positives = 180/432 (41%), Gaps = 60/432 (13%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYV-FSEHCG--AAYEDFNIQLRR---------SQES 128
            CS +GS HY TFDG  + F G C+YV   ++CG  ++   F+I               ++
Sbjct: 761  CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKA 820

Query: 129  AAPTLSRVLMKVDG---VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGL 185
                + R  +K++    VVIQ  +G      H V     + G        Y  VE+  G+
Sbjct: 821  IKIFMGRTELKLEDKHRVVIQRDEG------HHVAYTTREVG-------QYLVVESSTGI 867

Query: 186  VLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVS-ELLSHNTKLTPMEFGNLQKMDDP 244
            +++W+   ++ ++L   Y    CGLCG+F+           H    + ++FGN  K + P
Sbjct: 868  IVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK-EAP 926

Query: 245  TEQCQDPVPEP----PRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCED 300
            T       PEP    P   S     C  +L   +FS C + VD   + EAC  D C C+ 
Sbjct: 927  TCPDVSTNPEPCSLNPHRRSWAEKQCS-ILKSSVFSICHSKVDPKPFYEACVHDSCSCDT 985

Query: 301  TDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECR---SPCA----D 353
                 C C  +A Y+++CT  G     WR PD CP  C      HEC     PC     +
Sbjct: 986  GGDCECFCSAVASYAQECTKEGAC-VFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFE 1044

Query: 354  TCS--NQEHSRACEDHCVAGCF--CPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
            TC   N  HS     + + GC+  CP+   + +     CV   KC C      Y PGA+ 
Sbjct: 1045 TCRTINGIHSNISVSY-LEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASV 1103

Query: 410  STD--CTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTF-----DGKQYTV--HGDCSYVL 460
             T+  C +C C+    S Q V  P    +L       F      G   TV  H +   + 
Sbjct: 1104 PTEETCKSCVCTN---SSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNICSIT 1160

Query: 461  TKPCDSSAFTVL 472
            T+P   + FT +
Sbjct: 1161 TRPSTLTTFTTI 1172



 Score =  127 bits (319), Expect = 1e-28
 Identities = 130/523 (24%), Positives = 202/523 (38%), Gaps = 63/523 (12%)

Query: 425  CQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSA--FTVLAELRRCGLTD 482
            C    C   C+  G  H+ TFDG  Y+  G+C+YVL +    S   F V  +   C   D
Sbjct: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991

Query: 483  SETCLKSVTLSLDG----VQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQ 538
              +C +++ +  +     ++TV ++    +V +N+    LP     + +++    +++  
Sbjct: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051

Query: 539  TSLGLQLNLQ-LVPTMQL-FMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVV----EAT 592
              LG+ ++   L  +++L + +     +GQ CG C N  S   DD    SG +    EA 
Sbjct: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQ-CGTCTNTTS---DDCILPSGEIVSNCEAA 2107

Query: 593  AAAFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQH-------WCSQLTDADGPFGRCH 645
            A  +     ++  CP+  ++ + P        K   H        C  + D+   F +CH
Sbjct: 2108 ADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDS--LFAQCH 2165

Query: 646  AAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCP 705
            A V P  YY  C+FD+C    S    CA+L +Y   CA + + L  WR+      +  CP
Sbjct: 2166 ALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALCAQQNICL-DWRNHTHGACLVECP 2223

Query: 706  KSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYH 765
                Y       +PTC+S S          + V+GC CP+GT     G  V    C C  
Sbjct: 2224 SHREYQACGPAEEPTCKSSSSQQNNT----VLVEGCFCPEGTMNYAPGFDVCVKTCGCVG 2279

Query: 766  RGSMIPN--GESVHDSGAICTCTHGKLSCI-----GGQAPAPVCAAPMVFFDCRNATPGD 818
              + +P   GE        C C  G    I       Q P   C     +       P D
Sbjct: 2280 PDN-VPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYL-ATEVNPAD 2337

Query: 819  TGAGCQKSCHTLDMTCYSPQC-VPGCVCPDGLVADGE---GGCITAEDCP----CVHNEA 870
            T       C+     C +  C     VCP G     +   G C     C     CVH  A
Sbjct: 2338 T------CCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA 2391

Query: 871  SYRAGQTIRVG-CNTCTCDSR--------MWRCTDDPCLATCA 904
             Y+ G  +    C  C C  +        +  CT  PC  +C+
Sbjct: 2392 EYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434



 Score =  111 bits (278), Expect = 6e-24
 Identities = 113/414 (27%), Positives = 167/414 (40%), Gaps = 63/414 (15%)

Query: 894  CTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPC 953
            C    C   C  +GD HY+TFDG  YS+ G+C Y LV+        + D+F V  +N  C
Sbjct: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE----ISPSVDNFGVYIDNYHC 1987

Query: 954  GTTG-TTCSKAIKIFLGGFE--LKLSH---GKVEVIGTDESQEVPY-----TIRQMGIYL 1002
                  +C + + +     E  +K  H    +V+V    ++  +PY      + Q GI  
Sbjct: 1988 DPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINY 2047

Query: 1003 VVDTDIGLVLLWDKKTSIFINLS-PEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEF 1061
            VVD     VL+     S  + L    F     G CG   +   +D    S  +V +    
Sbjct: 2048 VVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAA 2107

Query: 1062 GNSWKLS----PSCP-DALAPKDPCT-------ANPFRKSWAQKQCSILHGPTFAACHAH 1109
             + W ++    P CP  +   K P           P +       C ++    FA CHA 
Sbjct: 2108 ADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHAL 2167

Query: 1110 VEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWR--TPSICPLFCDY 1167
            V P  YY+ACV D+C    G   E  C ++ AYA  C +  +C+ WR  T   C + C  
Sbjct: 2168 VPPQHYYDACVFDSCFM-PGSSLE--CASLQAYAALCAQQNICLDWRNHTHGACLVECPS 2224

Query: 1168 YNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPP----EAPIFDEDKMQ 1223
            +         YQ CG     TC++        V  +EGC+  CP      AP FD     
Sbjct: 2225 HR-------EYQACGPAEEPTCKSSSSQQNNTVL-VEGCF--CPEGTMNYAPGFD----V 2270

Query: 1224 CVATCPT--PPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEAC 1275
            CV TC    P   PR    G+ +        + +C++C+C E G     + + C
Sbjct: 2271 CVKTCGCVGPDNVPR--EFGEHF--------EFDCKNCVCLEGGSGIICQPKRC 2314



 Score =  109 bits (273), Expect = 2e-23
 Identities = 88/328 (26%), Positives = 139/328 (42%), Gaps = 38/328 (11%)

Query: 125 SQESAAPTLSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSY-------- 176
           +Q     T+  +  K   VV+  + GSVL+N   V LP   +   + + SSY        
Sbjct: 340 AQADLPKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAI 399

Query: 177 -TKVEARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVS-ELLSHNTKLTPME 234
             +++ +L  V+       L + LD     +  GLCG+FNG+     +  S   + T   
Sbjct: 400 GVRLQVQLAPVMQ------LFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAG 453

Query: 235 FGNLQKMD----DPTEQCQDPVPEPPRNCSTGFGICEELLHGQL-FSGCVALVDVGSYLE 289
           F N  K      D  +   DP      + +     C  L   +  F  C + VD   Y +
Sbjct: 454 FANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYK 513

Query: 290 ACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQ---KCPNNMQYHE 346
            C+ D C C++ +   C+C  L+ Y+R CT  G +   WR    C +    CPN+  +  
Sbjct: 514 RCKYDTCNCQNNE--DCLCAALSSYARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLY 570

Query: 347 CRSPCADTCSNQEHSRACEDHC------VAGCFCPEGTVLDDIGQTGCVPVSKCACVYNG 400
             + C  TC +   +   + HC      V GC CP+ T LD+ G+  CVP++KC+C + G
Sbjct: 571 NLTTCQQTCRSLSEA---DSHCLEGFAPVDGCGCPDHTFLDEKGR--CVPLAKCSCYHRG 625

Query: 401 AAYAPGATYSTDCTNCTCSGGRWSCQEV 428
                G         C C  GR  C+++
Sbjct: 626 LYLEAGDVVVRQEERCVCRDGRLHCRQI 653



 Score =  108 bits (271), Expect = 4e-23
 Identities = 110/402 (27%), Positives = 165/402 (41%), Gaps = 49/402 (12%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRR-----SQESAAPTLSR 135
            C+ WG  HY TFDG  + + G C YV  E    + ++F + +       + + + P    
Sbjct: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 2000

Query: 136  VLMKVDGVVIQLT-----KGSVLVNGHPVLLPFSQSGVLIQQSS-SYTKVEARLGLVLMW 189
            V  +   V+I+       +  V VN   V LP+ + G+ + QS  +Y      LG+++ +
Sbjct: 2001 VRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSY 2060

Query: 190  NHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKM-DDP---- 244
            N     +     ++ N T G CG          +L     ++  E    Q + +DP    
Sbjct: 2061 NGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPH 2120

Query: 245  -------TEQCQDPVP-----EPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACR 292
                   T++    VP      P ++C T   +C+ L+   LF+ C ALV    Y +AC 
Sbjct: 2121 CPHSSSTTKRPAVTVPGGGKTTPHKDC-TPSPLCQ-LIKDSLFAQCHALVPPQHYYDACV 2178

Query: 293  QDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDF--CPQKCPNNMQYHECRSP 350
             D CF   + L    C +L  Y+  C     +  DWR      C  +CP++ +Y  C   
Sbjct: 2179 FDSCFMPGSSL---ECASLQAYAALCAQQN-ICLDWRNHTHGACLVECPSHREYQACGPA 2234

Query: 351  CADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP---GA 407
               TC +   S+      V GCFCPEGT+    G   C  V  C CV  G    P   G 
Sbjct: 2235 EEPTCKSSS-SQQNNTVLVEGCFCPEGTMNYAPGFDVC--VKTCGCV--GPDNVPREFGE 2289

Query: 408  TYSTDCTNCTC--SGGRWSCQEVPC---PGTCSVLGGAHFST 444
             +  DC NC C   G    CQ   C   P T  V  G + +T
Sbjct: 2290 HFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLAT 2331



 Score =  102 bits (253), Expect = 5e-21
 Identities = 87/322 (27%), Positives = 141/322 (43%), Gaps = 28/322 (8%)

Query: 903  CAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSK 962
            C+ +G+ HY TFDG  + F G C+Y    + C G   +   F V  +  P         +
Sbjct: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASD-CRG---SYKEFAVHLKRGPGQAEAPAGVE 92

Query: 963  AIKIFLGGFELKLSHGKVEVIGTDESQ---EVPYTIRQMGIYLVVDTDIGLVLLWDKKTS 1019
            +I + +    + L+     + G   S         I +   Y  V +  GL L+W+++ +
Sbjct: 93   SILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDA 152

Query: 1020 IFINLSPEFKGRVCGLCGNFDDI-AVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPK 1078
            + + L  +F+   CGLCG+++ + + ++F   S  V+   LEFGN  K++   PD +   
Sbjct: 153  LMLELDTKFRNHTCGLCGDYNGLQSYSEFL--SDGVLFSPLEFGNMQKINQ--PDVVCED 208

Query: 1079 DPCTANPFRKSWAQKQCS-ILHGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCT 1137
                  P   S  + +C  +L    FA C   V    Y  AC  D C C  GGD  C C+
Sbjct: 209  PEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRC-PGGD-TCVCS 266

Query: 1138 AVAAYAQAC-HEVGLCVSWR--TPSICPLFCDYYNPEGQCEWH--YQPCGVPCLRTCRNP 1192
             VA +++ C H  G   +WR  T ++ P           C  +  Y   G PC+ TC + 
Sbjct: 267  TVAEFSRQCSHAGGRPGNWRTATSAVSP------GASKTCPGNLVYLESGSPCMDTCSHL 320

Query: 1193 RGDCLRDVWGLEGCYPKCPPEA 1214
                L +   ++GC+  CP  A
Sbjct: 321  EVSSLCEEHRMDGCF--CPEGA 340



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 144/574 (25%), Positives = 200/574 (34%), Gaps = 103/574 (17%)

Query: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRAS------GSSAPSSTPGTVSLSTART-- 1523
            TP+  +T+ +P  T     TP TT  TT T  +      G+  P+STP T + +   T  
Sbjct: 1360 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPT 1419

Query: 1524 ---TPAPGTATSVKKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQE 1580
               T  P T      T  TP+P P    + +  + TT  T   +  PT T+  T++ +  
Sbjct: 1420 PTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITT 1479

Query: 1581 LCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQD 1640
              T T       P P   G    T   +     T   +P       ++  +TP+      
Sbjct: 1480 TTTVT-------PTPTPTGTQTPTPTAITT---TTTVTPTPTPTGTQTPTSTPITTTTTV 1529

Query: 1641 VICSHTEGLICLNKNQLP-PICYNYEIRIQCCETVNVCRDITRPPKTVATT-RPTPHPTG 1698
                   G       Q P P   +    +    T    +  T  P T  TT  PTP PTG
Sbjct: 1530 TPTPTPTG------TQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 1583

Query: 1699 AQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV-------TRNCHPRCTWTK 1751
             QT TT      +  T  PT TS    T T +T  T  T         T    P  T T 
Sbjct: 1584 TQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTT 1643

Query: 1752 WFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQC 1811
                  P+ G  G    T    I         PE  T    R+ S P             
Sbjct: 1644 VTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLT----------- 1692

Query: 1812 SREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQST 1871
                                   E   L    P    +TST    PSTP+    +PT ++
Sbjct: 1693 -----------------------ESTTLLSTLPPAIEMTST--APPSTPT----APTTTS 1723

Query: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
                    T     STT++P  + T   TT ++SAPT       T +TT+ S  + T  P
Sbjct: 1724 GG-----HTLSPPPSTTTSPPGTPTRGTTTGSSSAPT-----PSTVQTTTTSAWTPTPTP 1773

Query: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAP-----------TSSTTSAPTTSTTSAPT 1980
             +TPS + TT     P++ +       T  AP           T    +   + T     
Sbjct: 1774 LSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYN 1833

Query: 1981 SSTTSSPQTSTTSAPTTSTTSGPGTTPS-PVPTT 2013
             S  S+P  + T + +T T S P +TPS P P T
Sbjct: 1834 WSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGT 1867



 Score = 97.8 bits (242), Expect = 9e-20
 Identities = 81/322 (25%), Positives = 129/322 (40%), Gaps = 20/322 (6%)

Query: 434 CSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRC-GLTDSETCLKSVTL 492
           CS  G  H+ TFDG  +   G C Y     C  S       L+R  G  ++   ++S+ L
Sbjct: 37  CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILL 96

Query: 493 SLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFF-IIAQTSLGLQLNLQLVP 551
           ++    T+ + +      LN      P  +  + I +   +  + ++  L L  N +   
Sbjct: 97  TIKD-DTIYLTRHLA--VLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDA- 152

Query: 552 TMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRN 611
              L ++L  K R  TCGLCG++N +Q+     LS  V  +   F N  K         +
Sbjct: 153 ---LMLELDTKFRNHTCGLCGDYNGLQSYS-EFLSDGVLFSPLEFGNMQKINQPDVVCED 208

Query: 612 SFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCL 671
             E+    S    +     C +L  A+  F  C   V    Y   C  D C C   + C+
Sbjct: 209 PEEEVAPASCSEHRAE---CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGGDTCV 264

Query: 672 CAALSSYVHACAAKGVQLGGWR---DGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGD 728
           C+ ++ +   C+  G + G WR     V      TCP ++ Y    S C  TC  L   +
Sbjct: 265 CSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHL---E 321

Query: 729 ITCSVGFIPVDGCICPKGTFLD 750
           ++       +DGC CP+G   D
Sbjct: 322 VSSLCEEHRMDGCFCPEGAQAD 343



 Score = 40.8 bits (94), Expect = 0.014
 Identities = 37/124 (29%), Positives = 47/124 (37%), Gaps = 19/124 (15%)

Query: 331  PDFCPQK----CPNNMQYHECRSPCADTCSNQEHSRACEDHCVAG-CFCPEGTVLDDIGQ 385
            P  C QK    C  +  Y       ADTC N    +     C      CP G  +     
Sbjct: 2311 PKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMV 2370

Query: 386  TG-CVPV----SKCACVYNGAAYAPGA-TYSTDCTNCTCSG--------GRWSCQEVPCP 431
             G C P     SK  CV+  A Y PG+  YS+ C +C C+            +C  VPC 
Sbjct: 2371 PGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCN 2430

Query: 432  GTCS 435
             +CS
Sbjct: 2431 TSCS 2434



 Score = 40.4 bits (93), Expect = 0.018
 Identities = 56/197 (28%), Positives = 72/197 (36%), Gaps = 39/197 (19%)

Query: 1321 TTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLP 1380
            T+  PP+T    T P   S  HT S  PS+  T PP +  PT   T+  +  PT      
Sbjct: 1708 TSTAPPST---PTAPTTTSGGHTLSPPPSTT-TSPPGT--PTRGTTTGSSSAPT------ 1755

Query: 1381 PVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLR 1440
            P   +    S W     P          T   +R  G R   S   + C   D    P  
Sbjct: 1756 PSTVQTTTTSAWTPTPTP--------LSTPSIIRTTGLRPYPSSVLICCVLNDTYYAP-- 1805

Query: 1441 ALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSSSPAQTTP-PTTSKTT 1499
              G+ V  +   G TC            Y +       L     S P+  +P PT SK+T
Sbjct: 1806 --GEEVY-NGTYGDTC------------YFVNCSLSCTLEFYNWSCPSTPSPTPTPSKST 1850

Query: 1500 ETRASGSSAPSS-TPGT 1515
             T +  SS PS  TPGT
Sbjct: 1851 PTPSKPSSTPSKPTPGT 1867



 Score = 33.1 bits (74), Expect = 2.8
 Identities = 30/92 (32%), Positives = 38/92 (41%), Gaps = 18/92 (19%)

Query: 1277 CTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPL 1336
            C  N   + PG+ +Y+ T G   C    C  + T+E   + C  T    PT  S STP  
Sbjct: 1796 CVLNDTYYAPGEEVYNGTYGDT-CYFVNCSLSCTLEFYNWSCPSTPSPTPTP-SKSTP-- 1851

Query: 1337 VVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSP 1368
                  TPS  PSS  + P       T GT P
Sbjct: 1852 ------TPSK-PSSTPSKP-------TPGTKP 1869



 Score = 32.3 bits (72), Expect = 4.8
 Identities = 53/258 (20%), Positives = 79/258 (30%), Gaps = 26/258 (10%)

Query: 699  KPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQA 758
            KP+T C +  TY         TC +++     C+         +CP G   +   K V  
Sbjct: 2317 KPVTHCVEDGTYLATEVNPADTCCNITV--CKCNTSLCKEKPSVCPLG--FEVKSKMVPG 2372

Query: 759  SNCP---------CYHRGSMIPNGESVHDSGAI-CTCT----HGKLSCIGGQAPAPVCAA 804
              CP         C H  +    G  V+ S    C CT    +  L  +      P   +
Sbjct: 2373 RCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTS 2432

Query: 805  PMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCP 864
                F+   A PG+    C K C         P      + P    +D +  C T   C 
Sbjct: 2433 CSPGFELMEA-PGE----CCKKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNC-TFFSCV 2486

Query: 865  CVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHY--LTFDGQSYSFN 922
             +HN+             +   C         + C  TC    +      T    +    
Sbjct: 2487 KIHNQLISSVSNITCPNFDASICIPGSITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSY 2546

Query: 923  GDCEYTLVQNHCGGKDST 940
              C  T++ NHC G   T
Sbjct: 2547 AGCTKTVLMNHCSGSCGT 2564


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score =  955 bits (2468), Expect = 0.0
 Identities = 671/2011 (33%), Positives = 920/2011 (45%), Gaps = 234/2011 (11%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSRVLMKV 140
            CSTWG+ H+ TFD  V+ F G CNY+F+  C  A+  F++QLRR  + +   +SR+++++
Sbjct: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGS---ISRIIVEL 101

Query: 141  DGVVIQLTKGSVLVNGHPVL-LPFSQSGVLIQ---QSSSYTKVEARLGLVLMWNHDDSLL 196
               V+ +++  + V    V+ LP++ +G+ I    QS      +  L L ++W  D  L+
Sbjct: 102  GASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLM 161

Query: 197  LELDTKYANKTCGLCGDFNGMPVVSELLSHNTK-LTPMEFGNLQKMDDPTEQCQ-DPVPE 254
            + ++ KY  + CGLCG+F+G  V +E +S   K L P +F  LQK+DDP E C    +P 
Sbjct: 162  VLVERKYMGQMCGLCGNFDGK-VTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPS 220

Query: 255  PPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEY 314
                 +    IC +LL           V    ++ +C+ D+         +  C TL+EY
Sbjct: 221  THVRQAQHARICTQLL---TLVAPECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEY 277

Query: 315  SRQCTHAGGLPQDWRGPDFCPQ-KCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCF 373
            SRQC+  G   + WR P  C   +CP N  Y EC S C  TCSN +HS  C   C  GCF
Sbjct: 278  SRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHS--CSSSCTFGCF 335

Query: 374  CPEGTVLDDIGQTG-CVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPG 432
            CPEGTVL+D+     CVPV++C CV +GA YAPG      C  C C+ GRW C E PCPG
Sbjct: 336  CPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPG 395

Query: 433  TCSVLGGAHFSTFDGKQYTVHGDCSYVLTK-PCDSSAFTVLAELRRCGLTDSETCLKSVT 491
             CS+ GG+  +TFD + Y  HG C+Y+L + P       ++A   + G++ SET L +V 
Sbjct: 396  HCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSETSLVAVV 455

Query: 492  LSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVP 551
                  Q  +VI     V  N     LP    N+T+FR ++  +   TS GL+L +QL P
Sbjct: 456  YL--SRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRP 513

Query: 552  TMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRN 611
              Q ++ + P+ RGQT GLCGNFN    DDF T  G+ E TA+ F ++++    CP    
Sbjct: 514  IFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA-GNCPAALE 572

Query: 612  SFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCL 671
               DPCS+S  N+  A+  CS L      F RCHA V P  +Y  C++  CN E +   +
Sbjct: 573  RETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHI 632

Query: 672  CAALSSYVHACAAKGVQLGGWRDGV--CTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDI 729
            CAAL  YVHAC+ +GV L GWR  V  CT P   C  + T+ Y+   C+ TC SLS+   
Sbjct: 633  CAALGDYVHACSLRGVLLWGWRSSVDNCTIP---CTGNTTFSYNSQACERTCLSLSDRAT 689

Query: 730  TCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRG-SMIPNGESVHDSGAICTCTHG 788
             C    +PVDGC CP GT+L+  G+CV+ + CPC   G   I   +S   +G  C C +G
Sbjct: 690  ECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCING 749

Query: 789  KLSCIGGQAPAPV---CAAPMVFFDCRNATPGDTGAGCQKSCHTL--DMTCYSPQCVPGC 843
            +LSC   Q P      C AP  F  C  ++    GA C  +C  L   + C   +C PGC
Sbjct: 750  RLSC--PQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGC 807

Query: 844  VCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDP-CLAT 902
            VC +GL  + +G C+  E+CPC  +  SY  G  +   C TC+C    W C     C +T
Sbjct: 808  VCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPST 867

Query: 903  CAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSK 962
            C +YG+GH +TFDGQ + F+G+CEY L  + CG  DS Q +F+++TENV CG +G TCS+
Sbjct: 868  CTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDS-QPTFKILTENVICGNSGVTCSR 926

Query: 963  AIKIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDTDI----GLVLLWDKKT 1018
            AIKIFLGG  + L+     V G  E   V   +    + LVVD  I     L L+W++  
Sbjct: 927  AIKIFLGGLSVVLADRNYTVTG--EEPHVQLGVTPGALSLVVDISIPGRYNLTLIWNRHM 984

Query: 1019 SIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPK 1078
            +I I ++   +  +CGLCGNF+    +DF TRSR V    LE  NSWK SP C D     
Sbjct: 985  TILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPLCGDVSFVT 1044

Query: 1079 DPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTA 1138
            DPC+ N FR+SWA+++CS+++  TFA CH+ V    YYEACV DAC CDSGGDCEC C A
Sbjct: 1045 DPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDA 1104

Query: 1139 VAAYAQACHEVGLCVSWRTPSICPLFCDYYN-------------PEGQCEWHYQPCGVPC 1185
            VAAYAQAC + G+CV WRTP+ CP++C +YN              E  C WHYQPC   C
Sbjct: 1105 VAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPC--LC 1162

Query: 1186 LRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCV----ATCPTPPLPPRCHVHG 1241
                ++  G        +EGCY  C  +   FD ++  CV     T P PP  P+    G
Sbjct: 1163 PSQPQSVPGS------NIEGCY-NCSQD-EYFDHEEGVCVPCMPPTTPQPPTTPQLPTTG 1214

Query: 1242 KSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYNGQRFHPGDVIYHTTDGTGGCI 1301
               RP  V P                                            GT   I
Sbjct: 1215 S--RPTQVWP------------------------------------------MTGTSTTI 1230

Query: 1302 SARCGANGTIERRVYPCSPT-TPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAW 1360
                    +      P SPT TP+ P T + S P    SS   P   P++A T   +S  
Sbjct: 1231 GLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKP--TASSGEPPR--PTTAVTPQATSGL 1286

Query: 1361 PTTAGTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRV 1420
            P TA        PT + +           +         R T      TL      G   
Sbjct: 1287 PPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTT-----MTLPTPATSG--- 1338

Query: 1421 CESPRSVECRAEDAPG-VPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPL 1479
              SP   +   ++ PG    +  G R   +   G T     Q +              P 
Sbjct: 1339 -TSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPT-------------RPT 1384

Query: 1480 ACSTS---SSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTARTT-PAPGTATSVKK 1535
            A  T+   ++   TTP T   T     +GS  PS+ P T +   A TT P P        
Sbjct: 1385 ATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHP----- 1439

Query: 1536 TFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTWTEWIDGSYPAP 1595
               T  P  VP  ST   S  TP T  V + PT  + +TS+      T      G+ P P
Sbjct: 1440 --ETTLPTHVPPFST---SLVTPSTHTVIT-PTHAQMATSASNHSAPT------GTIPPP 1487

Query: 1596 GINGGDFDTFQNLRDEGYTFCESP------RSVQCRAESFPNTPLADLGQDVICSHTEGL 1649
                        L+  G T    P       + Q  +    N     L      +H   +
Sbjct: 1488 ----------TTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEV 1537

Query: 1650 ICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHP---TGAQTQTTF- 1705
               +   + P   +   R     T +       PP T  +      P   TG  T T+F 
Sbjct: 1538 TPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFK 1597

Query: 1706 -TTHMPSASTEQPTATSRGGPTATS-VTQGTHT--TP------VTRNCHPRCTWTKWFDV 1755
             TT  P+ S  Q T  +   P +TS VT  THT  TP       + + H   T T    +
Sbjct: 1598 TTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGT----I 1653

Query: 1756 DFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREE 1815
              P+     G   T   +  +     +    +   +     H   S  H  +    S   
Sbjct: 1654 PPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTN 1713

Query: 1816 GLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQ 1875
              +  N    G                TP   P+T   VT   T   R+   T  TS+  
Sbjct: 1714 --ITPNPTSTG----------------TP---PMT---VTTSGTSQSRSSFSTAKTSTSL 1749

Query: 1876 KSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSA-----PTTRTTSASPASTT-- 1928
             S T++      TST  TS T  HT++ T  P A TTSA     PT  TT + P  TT  
Sbjct: 1750 HSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPI 1809

Query: 1929 --SGPGNTPSPVPTTSTISAPTTSITSAPT---TSTTSAPTSSTTSAPTTSTTSAPTSST 1983
              +GP  T +   TT+T   P+   T+ PT   + +TS  T ST +    + T   TS++
Sbjct: 1810 SSTGP-VTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSAS 1868

Query: 1984 TSSPQTSTTSAPTT-STTSGPGTTPSPVPTT 2013
              S  T T   PTT   T    T P   PTT
Sbjct: 1869 IHSMPTGTIPPPTTIKATGSTHTAPPMTPTT 1899



 Score =  126 bits (317), Expect = 2e-28
 Identities = 111/386 (28%), Positives = 160/386 (41%), Gaps = 37/386 (9%)

Query: 424 SCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDS 483
           S Q  P  G CS  G  HFSTFD   Y   G C+Y+    C  +  T   +LRR      
Sbjct: 35  SPQTAPDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSI 94

Query: 484 ETCLKSVTLSLDGV-QTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLG 542
              +  +  S+  V + ++ +K  G + L   YT    +   +T F  S   +  Q  L 
Sbjct: 95  SRIIVELGASVVTVSEAIISVKDIGVISLP--YTS---NGLQITPFGQSVRLVAKQ--LE 147

Query: 543 LQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT 602
           L+L +   P   L + +  K  GQ CGLCGNF+    ++F +  G        F    K 
Sbjct: 148 LELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-------KFLEPHKF 200

Query: 603 QAA----CPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCM 658
            A      P    +F+D  S  V   ++A+  C+QL     P   C  + +P  +  +C 
Sbjct: 201 AALQKLDDPGEICTFQDIPSTHVRQAQHAR-ICTQLLTLVAP--ECSVSKEP--FVLSCQ 255

Query: 659 FDTCNCER--SEDCLCAALSSYVHACAAKGVQLGGWRD-GVCTKPMTTCPKSMTYHYHVS 715
            D     +   ++  CA LS Y   C+  G  +  WR  G+C+  +  CP +  Y    S
Sbjct: 256 ADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCS--VGQCPANQVYQECGS 313

Query: 716 TCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGK---CVQASNCPCYHRGSMIPN 772
            C  TC   S    +CS       GC CP+GT L+D      CV  + CPC   G+M   
Sbjct: 314 ACVKTC---SNPQHSCSSSC--TFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAP 368

Query: 773 GESVHDSGAICTCTHGKLSCIGGQAP 798
           GE    +   C CT G+  C     P
Sbjct: 369 GEVTIAACQTCRCTLGRWVCTERPCP 394



 Score =  121 bits (303), Expect = 8e-27
 Identities = 108/420 (25%), Positives = 170/420 (40%), Gaps = 54/420 (12%)

Query: 883  NTCTCDSRMWRCTDDPCLAT----CAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKD 938
            NT      + R  D P  A     C+ +G GH+ TFD   Y F+G C Y           
Sbjct: 21   NTSYTSPGLQRLKDSPQTAPDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAA------- 73

Query: 939  STQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGKVEV--IGTDESQEVPYTIR 996
            + +D+F   +  +  G  G+     I + LG   + +S   + V  IG      +PYT  
Sbjct: 74   TCKDAFPTFSVQLRRGPDGSI--SRIIVELGASVVTVSEAIISVKDIGV---ISLPYTSN 128

Query: 997  QMGI--------YLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFA 1048
             + I         +    ++ L ++W   + + + +  ++ G++CGLCGNFD    N+F 
Sbjct: 129  GLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFV 188

Query: 1049 TRSRSVVGDVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHA 1108
            +     + +  +F    KL    P  +       +   R++   + C+ L       C  
Sbjct: 189  SEEGKFL-EPHKFAALQKLDD--PGEICTFQDIPSTHVRQAQHARICTQLLTLVAPECSV 245

Query: 1109 HVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCDY 1167
              EP  +  +C  D  A    G     C  ++ Y++ C  VG  V  WR+P +C +    
Sbjct: 246  SKEP--FVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSV---- 299

Query: 1168 YNPEGQCEWH--YQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFD-EDKMQC 1224
                GQC  +  YQ CG  C++TC NP+  C        GC+  CP    + D  +   C
Sbjct: 300  ----GQCPANQVYQECGSACVKTCSNPQHSCSSSC--TFGCF--CPEGTVLNDLSNNHTC 351

Query: 1225 VATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYNGQRF 1284
            V     P     C +HG  Y PG V  +   CQ+C CT     CT +     C+  G  F
Sbjct: 352  VPVTQCP-----CVLHGAMYAPGEVTIA--ACQTCRCTLGRWVCTERPCPGHCSLEGGSF 404



 Score =  100 bits (248), Expect = 2e-20
 Identities = 191/780 (24%), Positives = 288/780 (36%), Gaps = 117/780 (15%)

Query: 1319 SPTTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASAS 1378
            S T+  PP  F+  +PP    S+   S GP +A +   ++ +PT +   P+T LPT    
Sbjct: 1563 SATSSRPPPPFTTHSPP--TGSSPFSSTGPMTATSFKTTTTYPTPS--HPQTTLPT---H 1615

Query: 1379 LPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAED--APG 1436
            +PP        S    ++            T  ++ +        P +++       AP 
Sbjct: 1616 VPPFSTSLVTPSTHTVIT-----PTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPT 1670

Query: 1437 VPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSS---SPAQT-TP 1492
            + L   G          L+  N  + S   +++          + ST++   +P  T TP
Sbjct: 1671 MTLTTSGT------SQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTP 1724

Query: 1493 P---TTSKTTETRASGSSAPSST-----------PGTVSLSTARTTP---APGTATSVKK 1535
            P   TTS T+++R+S S+A +ST           P   S ST   TP   + GT T V  
Sbjct: 1725 PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAH 1784

Query: 1536 TFSTPS---PPPV----PATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTWTEWI 1588
            T S  S   P P     P T T+ +S+T P T+  S + T T P+ S     L T     
Sbjct: 1785 TTSATSSRLPTPFTTHSPPTGTTPISSTGPVTAT-SFQTTTTYPTPSHPHTTLPTHVPSF 1843

Query: 1589 DGSYPAPGINGGDFDTFQNLRDEGYTFC------ESPRSVQCRAESFPNTPLADLGQDVI 1642
              S   P  +     T   +                P +++    +    P+        
Sbjct: 1844 STSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTS 1903

Query: 1643 CSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQTQ 1702
             S +          LP   Y+         T     +IT    +  T  P  H T A + 
Sbjct: 1904 QSPSSFSTAKTSTSLP---YHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSS 1960

Query: 1703 ---TTFTTHMPSASTEQPTATSRGGPTATSV-TQGTHTTPVTRNCHPRCTWTKW---FDV 1755
               T FTTH P   +   ++T  G  TATS  T  T+ TP     HP+ T       F  
Sbjct: 1961 RLPTPFTTHSPPTGSSPFSST--GPMTATSFQTTTTYPTP----SHPQTTLPTHVPPFST 2014

Query: 1756 DFPSPGPHGGDKETYNNIIRSGEKICRRPEEI---TRLQCRAKSH--PEVSIEHLGQVVQ 1810
               +P  H     T+  +  S          +   T L+    +H  P +++   G    
Sbjct: 2015 SLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQT 2074

Query: 1811 CSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPS--GRAISPT 1868
             S        +        +  N   R          P  S+  T  ST +    + SP+
Sbjct: 2075 HSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPS 2134

Query: 1869 QSTSSWQKSRTTTLVTTSTTSTPQTSTTYA------HTTSTTSAPTARTTSAPTTRTTSA 1922
             S  S   S   +  ++  TS+P   T+ +      H+T+ +S   +  ++ PTT + SA
Sbjct: 2135 PSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSA 2194

Query: 1923 SP-------ASTT---------SGPGN----------TPSPVPTT----STISAPTTSIT 1952
            SP       ASTT         S P            T SP P++    STI+ P+T  T
Sbjct: 2195 SPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRT 2254

Query: 1953 SAPTTSTTSAPTSSTTSAPTTSTTSAPTS---STTSSPQTSTTSAPTTSTTSGPGTTPSP 2009
            +A T +  +  + STTS  T+ TT  PTS   S TS      TS  T  TT  PG T SP
Sbjct: 2255 TASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSP 2314



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 78/282 (27%), Positives = 120/282 (42%), Gaps = 32/282 (11%)

Query: 76   HNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVF-SEHCGAAYEDFNIQLRRSQ---ESAAP 131
            H    C+ +G  H  TFDG  F F G C Y+  ++ CG        ++        ++  
Sbjct: 863  HCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGV 922

Query: 132  TLSRVL-MKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYT--KVEARLGLVLM 188
            T SR + + + G+ + L   +  V G     P  Q GV     S      +  R  L L+
Sbjct: 923  TCSRAIKIFLGGLSVVLADRNYTVTGEE---PHVQLGVTPGALSLVVDISIPGRYNLTLI 979

Query: 189  WNHDDSLLLELDTKYANKTCGLCGDFNG-----------MPVVSEL-LSHNTKLTPMEFG 236
            WN   ++L+ +     +  CGLCG+FNG               SEL L ++ K +P+  G
Sbjct: 980  WNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPL-CG 1038

Query: 237  NLQKMDDPTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLC 296
            ++  + DP            R CS        +++ Q F+ C + V    Y EAC +D C
Sbjct: 1039 DVSFVTDPCSLNAFRRSWAERKCS--------VINSQTFATCHSKVYHLPYYEACVRDAC 1090

Query: 297  FCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKC 338
             C+      C+C  +A Y++ C    G+  DWR P FCP  C
Sbjct: 1091 GCDSGGDCECLCDAVAAYAQACLDK-GVCVDWRTPAFCPIYC 1131



 Score = 89.7 bits (221), Expect = 3e-17
 Identities = 190/788 (24%), Positives = 281/788 (35%), Gaps = 136/788 (17%)

Query: 1281 GQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPLVVSS 1340
            G R  P      TT   G     R  A  T + R      T   P TT S   PP   + 
Sbjct: 1361 GPRPTPASTTGPTTPQPGQ--PTRPTATETTQTRTTTEYTTPQTPHTTHS---PP--TAG 1413

Query: 1341 THTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGR 1400
            +  PS GP +A +   ++ +PT +   P T LPT    +PP        S    ++    
Sbjct: 1414 SPVPSTGPVTATSFHATTTYPTPS--HPETTLPT---HVPPFSTSLVTPSTHTVITP--- 1465

Query: 1401 GTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGLTCRNRE 1460
                           H      +           P   L+A G      P    T    +
Sbjct: 1466 --------------THAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQ 1511

Query: 1461 QASGLCYNYQIRVQCCTPLACSTSSS------PAQTTP----PTTSKTTETRASGSSAPS 1510
              S    N     +  T L   TSS+      P  TT     PT+++T    A  +SA S
Sbjct: 1512 AHSSFSTN-----KTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATS 1566

Query: 1511 STP-------GTVSLSTARTTPAPGTATSVKKTFSTPSPPPVPATSTS-----SMSTTTP 1558
            S P          + S+  ++  P TATS K T + P+P     T  +     S S  TP
Sbjct: 1567 SRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 1626

Query: 1559 GTSVVSSKPTLTEPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCES 1618
             T  V + PT  + +TS+ +  + T      G+ P P            L+  G T    
Sbjct: 1627 STHTVIT-PTHAQMATSASIHSMPT------GTIPPP----------TTLKATGSTHTAP 1669

Query: 1619 PRSVQCRAESFPNTPLADLGQDV-ICSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVC 1677
              ++     S   + L        + SHT                 +        T N+ 
Sbjct: 1670 TMTLTTSGTSQALSSLNTAKTSTSLHSHTSS--------------THHAEATSTSTTNIT 1715

Query: 1678 RDITR---PPKTVATTRPTPHPTGAQTQTTFTT-HMPSASTEQPTATSRGGPTATSVTQG 1733
             + T    PP TV T+  +   +   T  T T+ H  ++ST  P  TS    T+T+    
Sbjct: 1716 PNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS----TSTTSITP 1771

Query: 1734 THTTPVTRNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCR 1793
             HT+  TR   P    T       P+P            I  +G       +  T     
Sbjct: 1772 NHTSTGTRT--PVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYP-- 1827

Query: 1794 AKSHPEVSIE-HLGQ----VVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCET---PR 1845
              SHP  ++  H+      +V  S    ++  +       +M  +  +  +   T   P 
Sbjct: 1828 TPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHT------QMATSASIHSMPTGTIPPPT 1881

Query: 1846 GCPVTSTPVTAPS-TPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQ------TSTTYA 1898
                T +  TAP  TP+    S + S+ S  K+ T+    TS+T  P+      T+ T  
Sbjct: 1882 TIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPK 1941

Query: 1899 HTTSTTSAPTARTTSA-----PTTRTTSASPASTTSGPGNTPSPVPTTS--------TIS 1945
            HT++ T  P A TTSA     PT  TT + P  T S P ++  P+  TS        T S
Sbjct: 1942 HTSTGTRTPVAHTTSASSSRLPTPFTTHSPP--TGSSPFSSTGPMTATSFQTTTTYPTPS 1999

Query: 1946 APTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGT 2005
             P T++ +     +TS  T ST +   T+ T   TS++  S  T T   PTT   +G   
Sbjct: 2000 HPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTH 2059

Query: 2006 TPSPVPTT 2013
            T  P+  T
Sbjct: 2060 TAPPMTVT 2067



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 139/592 (23%), Positives = 209/592 (35%), Gaps = 108/592 (18%)

Query: 1483 TSSSPAQTTPPTTS---KTTETRASGSSAPSSTPGTVS-LSTARTTPAP----------- 1527
            T SSP  +T P T+   KTT T  + S   ++ P  V   ST+  TP+            
Sbjct: 1580 TGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQM 1639

Query: 1528 GTATSVKKTFSTPSPPPVPATSTSS------MSTTTPGTSVVSSKPTLTEPSTSSCLQEL 1581
             T+ S+    +   PPP    +T S      M+ TT GTS   S  +L    TS+ L   
Sbjct: 1640 ATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALS--SLNTAKTSTSLHSH 1697

Query: 1582 CTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDV 1641
             + T   + +  +            N+     +    P +V     S   +  +      
Sbjct: 1698 TSSTHHAEATSTST----------TNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTST 1747

Query: 1642 -ICSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQ 1700
             + SHT               ++ E+      T      IT    +  T  P  H T A 
Sbjct: 1748 SLHSHTSST------------HHPEV------TSTSTTSITPNHTSTGTRTPVAHTTSAT 1789

Query: 1701 TQ---TTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPRC-TWTKWFDVD 1756
            +    T FTTH P   T   T  S  GP   +  Q T T P   + H    T    F   
Sbjct: 1790 SSRLPTPFTTHSPPTGT---TPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTS 1846

Query: 1757 FPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEG 1816
              +P  H     T+  +  S          I          P  +I+  G          
Sbjct: 1847 LVTPSTHTVIIPTHTQMATSASIHSMPTGTIP---------PPTTIKATGSTHTAPPMTP 1897

Query: 1817 LVCRNQDQQGPF---KMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSS 1873
                       F   K   +          P   P ++T +T   T +G   +P   T+S
Sbjct: 1898 TTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTR-TPVAHTTS 1956

Query: 1874 WQKSRTTTLVTTSTTST---------PQTSTTYAHTTSTTSAPTARTTSAPT-------- 1916
               SR  T  TT +  T         P T+T++  TT+T   P+   T+ PT        
Sbjct: 1957 ASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSF-QTTTTYPTPSHPQTTLPTHVPPFSTS 2015

Query: 1917 ------------TRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPT 1964
                        T T  A+ AS  S P  T   VP  +T+ A  ++ T+ P T TTS  +
Sbjct: 2016 LVTPSTHTVIITTHTQMATSASIHSTPTGT---VPPPTTLKATGSTHTAPPMTVTTSGTS 2072

Query: 1965 SSTTSAPTTSTTSAPTSSTTSSPQTSTT---SAPTTSTTSGPGTTPSPVPTT 2013
             + +S  T + +S+  SS++  PQ S++   S+P T+      +  +PV TT
Sbjct: 2073 QTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTT 2124



 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 147/703 (20%), Positives = 233/703 (33%), Gaps = 92/703 (13%)

Query: 1308 NGTIERRVYPCSPTTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTS 1367
            +GT + R    +  T     + + ST    V+ST T S  P+   TG  +    TT+ TS
Sbjct: 1731 SGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATS 1790

Query: 1368 PRTRLPTASASLPPVCGEKCLWS--PWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPR 1425
              +RLPT   +  P  G   + S  P    S     T          L  H      S  
Sbjct: 1791 --SRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLV 1848

Query: 1426 SVECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSS 1485
            +        P     A    +   P   +      +A+G  +         TP    TS 
Sbjct: 1849 TPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHT----APPMTPTTSGTSQ 1904

Query: 1486 SPAQTTPPTTSKTTETRASGSSAPSSTPGTVS------LSTARTTPAPGTATSVKKTFST 1539
            SP+  +   TS +     S +  P  TP + +       ST   TP   T ++      T
Sbjct: 1905 SPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPT 1964

Query: 1540 PSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTWTEWIDGSYPAPGING 1599
            P     P T +S  S+T P T+  S + T T P+ S     L T       S   P  + 
Sbjct: 1965 PFTTHSPPTGSSPFSSTGPMTAT-SFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHT 2023

Query: 1600 GDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICSHTEGLICLNKNQLPP 1659
                T   +            +V       P T L   G     +HT   + +  +    
Sbjct: 2024 VIITTHTQMATSASIHSTPTGTVP------PPTTLKATGS----THTAPPMTVTTSGTSQ 2073

Query: 1660 ICYNYEIRIQCCETVNVC-----RDITRPPKTVATTRPTPHPTGAQTQTTFTTHMPSAST 1714
               ++         ++          +RPP +  TT+  PH + A T  + T  + S+ +
Sbjct: 2074 THSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQ-LPHLSSATTPVSTTNQLSSSFS 2132

Query: 1715 EQPTATSRGGPTATSVTQGTHTTPVTRNCHPRCTWTKWFDVDFPSPGPHGG--DKETYNN 1772
              P+A S    T +S    +H++P T +               PS G          ++ 
Sbjct: 2133 PSPSAPS----TVSSYVPSSHSSPQTSS---------------PSVGTSSSFVSAPVHST 2173

Query: 1773 IIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRN---QDQQGPFK 1829
             + SG                  +HP  +      +   S       R         PF 
Sbjct: 2174 TLSSGS------------HSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFT 2221

Query: 1830 MCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTS 1889
            +     +  +         + S+ +  PSTP  R  + T +  ++    TT+  T+ TT 
Sbjct: 2222 LSALLPISTVTVSPTPSSHLASSTIAFPSTP--RTTASTHTAPAFSSQSTTSRSTSLTTR 2279

Query: 1890 TPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTT 1949
             P TS   + T+  T  PT+     P T  T+  P  T S                 PTT
Sbjct: 2280 VP-TSGFVSLTSGVTGIPTS-----PVTNLTTRHPGPTLS-----------------PTT 2316

Query: 1950 SITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTT 1992
               ++  T+  S P S+  S+  T T ++P   +    Q   T
Sbjct: 2317 RFLTSSLTAHGSTPASAPVSSLGTPTPTSPGVCSVREQQEEIT 2359



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 62/199 (31%), Positives = 86/199 (43%), Gaps = 35/199 (17%)

Query: 1850 TSTPVTAPSTPSGRAIS--PTQSTSSWQKSRTTTLVTTST------------TSTPQTST 1895
            T+T    PS P     +  P  STS    S  T ++TT T            T T    T
Sbjct: 1991 TTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPT 2050

Query: 1896 TYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSG---------PGNTPSPVPTTS-TIS 1945
            T   T ST +AP    T++ T++T S+   +T S          P N+ S  P++  T  
Sbjct: 2051 TLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQ 2110

Query: 1946 APTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTST---------TSAPT 1996
             P  S  + P ++T    +S + S    ST S+   S+ SSPQTS+          SAP 
Sbjct: 2111 LPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPV 2170

Query: 1997 TSTT--SGPGTTPSPVPTT 2013
             STT  SG  ++ S  PTT
Sbjct: 2171 HSTTLSSGSHSSLSTHPTT 2189


>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
          Length = 2813

 Score =  763 bits (1971), Expect = 0.0
 Identities = 425/1258 (33%), Positives = 614/1258 (48%), Gaps = 86/1258 (6%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSRVLMKV 140
            CS +GS    TFDG ++ F G C+Y+ +  C      F+I +   Q     +LS  L + 
Sbjct: 35   CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQK--RSFSI-IGDFQNGKRVSLSVYLGEF 91

Query: 141  DGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARL-GLVLMWNHDDSLLLEL 199
              + +    G+V      V +P++  G+ ++  + Y K+     G V   +   +  + L
Sbjct: 92   FDIHL-FVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQVLL 150

Query: 200  DTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMDDPTEQCQDPVPEPPR 257
              +Y NKTCGLCG+FN +    + ++    LT  P +F N   +    + C+   P P  
Sbjct: 151  SDRYFNKTCGLCGNFN-IFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERASP-PSS 208

Query: 258  NCSTGFGI--------CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCH 309
            +C+   G         C+ L    +F+ C  LVD   ++  C + LC C     L C C 
Sbjct: 209  SCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGG--LECACP 266

Query: 310  TLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCV 369
             L EY+R C   G +   W     C   CP  M+Y +C SPCA TC +   +  C++ CV
Sbjct: 267  ALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCV 326

Query: 370  AGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVP 429
             GC CPEG +LD+     CV  ++C CV++G  Y PG + S DC  C C   +W C    
Sbjct: 327  DGCSCPEGQLLDE---GLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWICSNEE 383

Query: 430  CPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKS 489
            CPG C V G +HF +FD + +T  G C Y+L + C   +F+++ E  +C       C +S
Sbjct: 384  CPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDAVCTRS 443

Query: 490  VTLSLDGVQ-TVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQ 548
            VT+ L G+  ++V +K    V ++    QLP+   ++ I    T  +  + S G  L + 
Sbjct: 444  VTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASV--RLSYGEDLQMD 501

Query: 549  LVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPN 608
                 +L ++L+P   G+TCGLCGN+N  Q DDF T SG+ E     F N +K    C +
Sbjct: 502  WDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQD 561

Query: 609  IRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSE 668
            ++    DPC+L+    ++++  C+ LT     F  CH AV P  Y  NC +D C+C    
Sbjct: 562  LQKQHSDPCALNPRMTRFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGR 619

Query: 669  DCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGD 728
            +CLC AL+SY  ACA +GV++     G C      CPK   Y    + C  TCRSLS  D
Sbjct: 620  ECLCGALASYAAACAGRGVRVAWREPGRCE---LNCPKGQVYLQCGTPCNLTCRSLSYPD 676

Query: 729  ITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHG 788
              C+   +  +GC CP G ++D+ G CV  + CPCY+ G +    +   D   +C C  G
Sbjct: 677  EECNEACL--EGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDG 734

Query: 789  KLSCIGGQAPAPV-------------------CAAPMVFFDCRNATPGDTGAGCQKSCHT 829
             + C     P  +                   C  PMV   C        G  C K+C  
Sbjct: 735  FMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTCQN 794

Query: 830  LDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDS 889
             D+ C S  CV GC+CP G+V   E  C+  E CPC H    Y  G+T+++GCNTC C  
Sbjct: 795  YDLECMSMGCVSGCLCPPGMVRH-ENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRD 853

Query: 890  RMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTE 949
            R W CTD  C ATC+  G  HYLTFDG  Y F G+C+Y LVQ++CG    T   FR++  
Sbjct: 854  RKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGT---FRILVG 910

Query: 950  NVPCGTTGTTCSKAIKIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDTDIG 1009
            N  C      C K + I + G E++L  G+V V       E  + + + G Y+++     
Sbjct: 911  NKGCSHPSVKCKKRVTILVEGGEIELFDGEVNV-KRPMKDETHFEVVESGRYIILLLGKA 969

Query: 1010 LVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSP 1069
            L ++WD+  SI + L   ++ +VCGLCGNFD I  ND  + +  V  D ++FGNSWK+S 
Sbjct: 970  LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSS 1029

Query: 1070 SCPDA-LAPKD----PCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDAC 1124
             C D    P D     C  N  +++     C IL    F  C+  V+P  Y + C+ D C
Sbjct: 1030 QCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTC 1089

Query: 1125 ACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEG---QCEWHYQPC 1181
            +C+S GDC CFC  +AAYA  C + G  V+WRT ++CP  C+  N      +CEW Y  C
Sbjct: 1090 SCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSC 1149

Query: 1182 GVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHG 1241
               C  TC++P       V  +EGC+  CPP   I DE     + TC  P   P C V G
Sbjct: 1150 APACQVTCQHPE-PLACPVQCVEGCHAHCPP-GKILDE----LLQTCVDPEDCPVCEVAG 1203

Query: 1242 KSYRPGAVV---PSD-KNCQSCLCTERGVECTYKAEACVCTYNGQRFHPGDVIYHTTD 1295
            + +  G  V   PSD ++CQ C C    + C    EAC          PG ++   TD
Sbjct: 1204 RRFASGKKVTLNPSDPEHCQICHCDVVNLTC----EACQ--------EPGGLVVPPTD 1249



 Score =  141 bits (356), Expect = 6e-33
 Identities = 120/418 (28%), Positives = 174/418 (41%), Gaps = 48/418 (11%)

Query: 901  ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTC 960
            A C+++G     TFDG  YSF G C Y L     GG    + SF ++      G      
Sbjct: 33   ARCSLFGSDFVNTFDGSMYSFAGYCSYLL----AGG--CQKRSFSII------GDFQNGK 80

Query: 961  SKAIKIFLGG-FELKLSHGKVEVIGTDESQEVPYTIR------QMGIYLVVDTDIGLVLL 1013
              ++ ++LG  F++ L        G D+   +PY  +      + G Y +     G V  
Sbjct: 81   RVSLSVYLGEFFDIHLFVNGTVTQG-DQRVSMPYASKGLYLETEAGYYKLSGEAYGFVAR 139

Query: 1014 WDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPS--- 1070
             D   +  + LS  +  + CGLCGNF+  A +DF T+  ++  D  +F NSW LS     
Sbjct: 140  IDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQW 199

Query: 1071 CPDALAPKDPCT-ANPFRKSWAQKQCSILHGPT-FAACHAHVEPARYYEACVNDACACDS 1128
            C  A  P   C  ++   +    +QC +L   + FA CH  V+P  +   C    C C  
Sbjct: 200  CERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCEC-- 257

Query: 1129 GGDCECFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLR 1187
             G  EC C A+  YA+ C + G+ +  W   S C   C    P G     Y+ C  PC R
Sbjct: 258  AGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC----PAGM---EYRQCVSPCAR 310

Query: 1188 TCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPG 1247
            TC++   + +     ++GC   C PE  + DE        CP       C   GK Y PG
Sbjct: 311  TCQSLHINEMCQERCVDGC--SC-PEGQLLDEGLCVESTECP-------CVHSGKRYPPG 360

Query: 1248 AVVPSDKNCQSCLCTERGVECTYKAEACVCTYNGQ-RFHPGDVIYHTTDGTGGCISAR 1304
              +  D  C +C+C      C+ +     C   GQ  F   D  Y T  G    + AR
Sbjct: 361  TSLSRD--CNTCICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLAR 416



 Score =  125 bits (313), Expect = 5e-28
 Identities = 143/574 (24%), Positives = 214/574 (37%), Gaps = 122/574 (21%)

Query: 417  TCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELR 476
            TC G RW+C   PC   C+     H  TFDG+ + + G CSYVL +  +     V+    
Sbjct: 1939 TC-GCRWTC---PC--VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD-LEVILHNG 1991

Query: 477  RCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTI-FRPSTFFI 535
             C     + C+KS+ +    +   V + +  EV +N     +P    N+ +    +    
Sbjct: 1992 ACSPGARQGCMKSIEVKHSALS--VELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHE 2049

Query: 536  IAQTSLGLQLNLQLVPTMQLFMQLAPK-LRGQTCGLCGNFNSIQADDFRTLSGVVEATAA 594
            +    LG  +        +  +QL+PK    +T GLCG  +   A+DF    G V     
Sbjct: 2050 VRFNHLG-HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWK 2108

Query: 595  AFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYY 654
                 +  Q      +   E+ C   V +  + Q     L      F  CH  + P T+Y
Sbjct: 2109 TLVQEWTVQRPGQTCQPILEEQC--LVPDSSHCQVLLLPL------FAECHKVLAPATFY 2160

Query: 655  SNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHV 714
            + C  D+C+ E+    +C  ++SY H C   GV +       C     +CP S+ Y++  
Sbjct: 2161 AICQQDSCHQEQ----VCEVIASYAHLCRTNGVCVDWRTPDFCA---MSCPPSLVYNH-- 2211

Query: 715  STCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNC-PCYHRGSM---- 769
              C+  C    +G+++ S G  P +GC CP    + + G CV    C  C     +    
Sbjct: 2212 --CEHGCPRHCDGNVS-SCGDHPSEGCFCPPDKVMLE-GSCVPEEACTQCIGEDGVQHQF 2267

Query: 770  ----IPNGESVHDSGAICTCTHG-KLSCIGGQAP---APVCAAPMVF------------F 809
                +P+    H    ICTC  G K++C     P   AP C    V             +
Sbjct: 2268 LEAWVPD----HQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEY 2323

Query: 810  DC----------------RNATPGDTGAG---------CQK---------SC--HTL--- 830
            +C                R   P  T  G         C+K         SC  H L   
Sbjct: 2324 ECVCDPVSCDLPPVPHCERGLQPTLTNPGECRPNFTCACRKEECKRVSPPSCPPHRLPTL 2383

Query: 831  --DMTCYSPQCVPGCV-----CPDGLVAD---GEGGCITAEDCP---CVHNEASYRAGQT 877
                 C   +C   CV     CP G +A     + GC T    P   CVH    Y  GQ 
Sbjct: 2384 RKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQF 2443

Query: 878  IRVGCNTCTCDS--------RMWRCTDDPCLATC 903
               GC+ CTC          R+ +C+  PC  +C
Sbjct: 2444 WEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSC 2477



 Score =  125 bits (313), Expect = 5e-28
 Identities = 113/402 (28%), Positives = 157/402 (39%), Gaps = 64/402 (15%)

Query: 884  TCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDS 943
            TC C    W C   PC+  C      H +TFDGQ++   G C Y L QN        +  
Sbjct: 1939 TCGC---RWTC---PCV--CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNK-------EQD 1983

Query: 944  FRVVTENVPCGTTGTT-CSKAIKIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYL 1002
              V+  N  C       C K+I++      ++L H  +EV        VPY    M + +
Sbjct: 1984 LEVILHNGACSPGARQGCMKSIEVKHSALSVEL-HSDMEVTVNGRLVSVPYVGGNMEVNV 2042

Query: 1003 -------VVDTDIGLVLLWDKKTSIF-INLSPE-FKGRVCGLCGNFDDIAVNDFATRSRS 1053
                   V    +G +  +  + + F + LSP+ F  +  GLCG  D+   NDF  R  +
Sbjct: 2043 YGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGT 2102

Query: 1054 VVGDVLEFGNSWKLS---PSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHV 1110
            V  D       W +     +C   L  ++ C             C +L  P FA CH  +
Sbjct: 2103 VTTDWKTLVQEWTVQRPGQTCQPIL--EEQCLVPD------SSHCQVLLLPLFAECHKVL 2154

Query: 1111 EPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNP 1170
             PA +Y  C  D+C        E  C  +A+YA  C   G+CV WRTP  C + C    P
Sbjct: 2155 APATFYAICQQDSC------HQEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSC----P 2204

Query: 1171 EGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPT 1230
                   Y  C   C R C      C       EGC+  CPP       DK+    +C  
Sbjct: 2205 PSLV---YNHCEHGCPRHCDGNVSSC--GDHPSEGCF--CPP-------DKVMLEGSCVP 2250

Query: 1231 PPLPPRC-HVHGKSYR-PGAVVPSDKNCQSCLC-TERGVECT 1269
                 +C    G  ++   A VP  + CQ C C + R V CT
Sbjct: 2251 EEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCT 2292



 Score =  109 bits (273), Expect = 2e-23
 Identities = 102/371 (27%), Positives = 161/371 (43%), Gaps = 41/371 (11%)

Query: 80   VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRR---SQESAAPTLSRV 136
            VC+   + H  TFDG  F+  G C+YV  ++     +D  + L     S  +    +  +
Sbjct: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN---KEQDLEVILHNGACSPGARQGCMKSI 2005

Query: 137  LMKVDGVVIQLTKG-SVLVNGHPVLLPFSQSGVLIQQSSSYTKVEAR---LGLVLMWN-H 191
             +K   + ++L     V VNG  V +P+    + +    +    E R   LG +  +   
Sbjct: 2006 EVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMH-EVRFNHLGHIFTFTPQ 2064

Query: 192  DDSLLLELDTK-YANKTCGLCG--DFNGMPVVSELLSHNTKLTPMEFGNLQK--MDDPTE 246
            ++   L+L  K +A+KT GLCG  D NG    ++ +  +  +T      +Q+  +  P +
Sbjct: 2065 NNEFQLQLSPKTFASKTYGLCGICDENG---ANDFMLRDGTVTTDWKTLVQEWTVQRPGQ 2121

Query: 247  QCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSC 306
             CQ  + E    C        ++L   LF+ C  ++   ++   C+QD C  E       
Sbjct: 2122 TCQPILEE---QCLVPDSSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQ------ 2172

Query: 307  VCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACED 366
            VC  +A Y+  C    G+  DWR PDFC   CP ++ Y+ C   C   C     S  C D
Sbjct: 2173 VCEVIASYAHLC-RTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVSS--CGD 2229

Query: 367  HCVAGCFCPEGTVLDDIGQTGCVPVSKCA-CV-YNGAAYAPGATYSTD---CTNCTC-SG 420
            H   GCFCP   V+    +  CVP   C  C+  +G  +     +  D   C  CTC SG
Sbjct: 2230 HPSEGCFCPPDKVM---LEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSG 2286

Query: 421  GRWSCQEVPCP 431
             + +C   PCP
Sbjct: 2287 RKVNCTTQPCP 2297



 Score = 38.9 bits (89), Expect = 0.051
 Identities = 65/280 (23%), Positives = 96/280 (34%), Gaps = 57/280 (20%)

Query: 289  EACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECR 348
            + C +  C C   D +SC    +    R      GL      P  C        +  EC+
Sbjct: 2318 QCCPEYECVC---DPVSCDLPPVPHCER------GLQPTLTNPGECRPNFTCACRKEECK 2368

Query: 349  SPCADTCSNQE-----HSRACEDH-CVAGCF-----CPEG----TVLDDIGQTGCVPVSK 393
                 +C          ++ C+++ C   C      CP G    T  +D G T    +  
Sbjct: 2369 RVSPPSCPPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGCTTTTCLPD 2428

Query: 394  CACVYNGAAYAPGATYSTDCTNCTCS-------GGRWS-CQEVPCPGTCSVLGGAHFSTF 445
              CV+    Y  G  +   C  CTC+       G R + C + PC  +C           
Sbjct: 2429 KVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCR---------- 2478

Query: 446  DGKQYTVH-GDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVI- 503
             G  Y +H G+C       C  SA  V+    R    DS++  KSV       +   +I 
Sbjct: 2479 SGFTYVLHEGEC----CGRCLPSACEVVTGSPR---GDSQSSWKSVGSQWASPENPCLIN 2531

Query: 504  ---KASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTS 540
               +   EVF+ Q     P     V    PS F +  +TS
Sbjct: 2532 ECVRVKEEVFIQQRNVSCPQLEVPVC---PSGFQLSCKTS 2568



 Score = 38.1 bits (87), Expect = 0.088
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 16/73 (21%)

Query: 374  CPEGTVLDDIGQTGCVPVSKC----ACVYNGAAYAPGATYSTD-CTNCTC-------SGG 421
            CP G  L     + C P  +C    AC+ NG    PG T   D CT C C       SG 
Sbjct: 2557 CPSGFQLS-CKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTTCRCMVQVGVISGF 2615

Query: 422  RWSCQEV---PCP 431
            +  C++    PCP
Sbjct: 2616 KLECRKTTCNPCP 2628


>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
            sapiens]
          Length = 2134

 Score =  754 bits (1948), Expect = 0.0
 Identities = 458/1373 (33%), Positives = 655/1373 (47%), Gaps = 103/1373 (7%)

Query: 248  CQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGS-YLEACRQDLCFCEDTDLLSC 306
            C + V +    C  G   C +++ G  F  C  +  + + Y   C  + C   D    + 
Sbjct: 671  CPNAVGKSYEVCEDGIQHCNKII-GTYFEKCGKVAALSNDYKMICIDEYCQTRDK---TS 726

Query: 307  VCHTLAEYSRQCTHAG-GLPQDWRGPD--FCP-QKCPNNMQYHECRSPCADTCSNQEHSR 362
             C T +E SR C   G G  + WR      C  Q+CP    Y EC      TCSN    +
Sbjct: 727  TCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPFQ 786

Query: 363  ACEDHCVAGCFCPEGTVLDDIGQTG-CVPVSKCACVYNGAAYAPGATYSTDC-TNCTCSG 420
              E  CV+GC CPEG +LDDIG+ G CV  ++C C  +G  Y PG      C + CTC  
Sbjct: 787  DSE--CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQD 844

Query: 421  GRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGL 480
             +WSC E  CPG C V G +  +TFDG +Y   G+C ++     D   +++  ELR C  
Sbjct: 845  AKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVHNED---WSISVELRPCPS 900

Query: 481  TDSETCLKSVTLSLDGVQTV--VVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQ 538
              + TCL SVTL L+    V   V  + G V  ++I  Q    +  + IF  S+ ++  +
Sbjct: 901  GQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVE 960

Query: 539  TSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFN 598
            T   ++L +Q+VP MQL++ + P     T GLCG++N+   DDF +   ++E T+ AF N
Sbjct: 961  TYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFAN 1020

Query: 599  TFKTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCM 658
            +++  + CP    S      +S+E EK+A+  C  L D+ GP   CH  V P  Y+  C 
Sbjct: 1021 SWEMMS-CPKGNPS----SCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECK 1075

Query: 659  FDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQ 718
              TC CE S+DCLC  L +YV ACA K   + GWR G+C     +CP  + + Y+V  C 
Sbjct: 1076 KYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEH---SCPSGLVFKYNVKACN 1132

Query: 719  PTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHD 778
             +CRSLSE D +C V  +PVDGC CP   + ++ G CV  S C CY    ++  G+ +H 
Sbjct: 1133 SSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHI 1192

Query: 779  SGAICTCTHGKLSCIGGQAPAPV----CAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTC 834
                C C  G L C   Q P  +    C+    + DC +           ++C T ++  
Sbjct: 1193 DDNKCVCRDGILLC---QIPIDLTLQNCSGGAEYVDCSDPK---AQRRTNRTCSTRNIPV 1246

Query: 835  YSPQ--CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMW 892
            +     C  GC CP+G+V + +G C+   DCPC      Y  G    VGCN CTC    W
Sbjct: 1247 FDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSW 1306

Query: 893  RCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVP 952
             CT + C   C +YG+GH  TFDG+SYSF+G C+Y+ ++++CG ++ T   FR++TE+VP
Sbjct: 1307 SCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGT---FRILTESVP 1363

Query: 953  CGTTGTTCSKAIKIFLGGFELKLSHGKVEVIGTDESQEVP-----YTIRQMGIYLVVDTD 1007
            C   G TCS+ I +      + L  GKV  + + ES++       Y+I  +G+YL++   
Sbjct: 1364 CCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQ 1423

Query: 1008 IGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL 1067
             G++++WDK T + + L P + G+VCGLCGN +    +DF TR  SV    LEFGNSWK 
Sbjct: 1424 NGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT 1483

Query: 1068 SPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDACACD 1127
            S  C D +A   PC +NP+ K+WA ++C IL   TF  CH  V+P+ Y++ C+ +ACACD
Sbjct: 1484 SQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACD 1543

Query: 1128 SGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLR 1187
              G    FCTAVA YA+AC  VG+CVSWR P++CP++CDYYN  G+C WHY+PCG    +
Sbjct: 1544 MEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAK 1603

Query: 1188 TCRNPR-GDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRP 1246
            TC++   G     +  LEGCY KCP  AP  DE+ M+CV+          C        P
Sbjct: 1604 TCKDQLVGQKFSSL--LEGCYAKCPDSAPYLDENTMKCVSL-------SECSCFYNDVIP 1654

Query: 1247 GAVVPSDKNCQSCLCTERGVECTYKAE-----ACVCTYNGQRFHPGDVIYHTTDGTGGCI 1301
               V  D   ++C C    +EC+  A      A   T        G  I   T G     
Sbjct: 1655 AGGVIEDNCGRTCYCIAGQLECSETAPTNSTFAVSTTTATTILSTGAAITLVTGGPSTAA 1714

Query: 1302 SARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWP 1361
            S       + E       P T    T  + ++ P++ +S +    G  S      S    
Sbjct: 1715 SIPAITTSSSETTGTTLGPLTEPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAG 1774

Query: 1362 TTAG------------TSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDT 1409
            TT G            TS R   P  S + P V G           S PG          
Sbjct: 1775 TTGGVDAATTGAASENTSERAGTPRVSGATPAVGGG----------STPGEAGPGATVSG 1824

Query: 1410 LENLRAHGYRVCESPRSVECRAEDA-PGVPLRALGQRVQCSPDVGLTCRNREQASGLCYN 1468
               + A    +  SP +    +E +  G    ++G +       G T      + G+   
Sbjct: 1825 STGVSAGS--ITASPGASATSSESSKSGTTGPSVGGK------TGATSSEATSSEGMS-- 1874

Query: 1469 YQIRVQCCTPLACSTSSSPAQTTPPTTSKTTE-TRASGSSAPSSTPGTVSLSTARTTPAP 1527
              +  Q     A S S   A+T+   +S   + TR S  S    + GT       TT A 
Sbjct: 1875 -GVTGQSLGSTAGSDSEITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAA 1933

Query: 1528 GTATS------VKKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPST 1574
            G  TS           +T S        TS    T PG + VS  P ++  +T
Sbjct: 1934 GENTSGALGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGAT 1986



 Score =  126 bits (317), Expect = 2e-28
 Identities = 102/371 (27%), Positives = 157/371 (42%), Gaps = 31/371 (8%)

Query: 80   VCSTWGSFHYKTFDGDVFRFPGLCNYVFSE-HCGAAYEDFNIQLRRSQESAAP--TLSR- 135
            +C  +G  H +TFDG  + F GLC Y F E +CG     F I L  S        T SR 
Sbjct: 1316 ICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRI-LTESVPCCEDGLTCSRK 1374

Query: 136  --VLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDD 193
              V  +   +V+Q  K + + +        + +   I     Y  ++ + G++++W+ + 
Sbjct: 1375 IIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNT 1434

Query: 194  SLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMDDPTEQCQD- 250
             L + LD  +  K CGLCG+ NG  +  +  +  + +    +EFGN  K    +++C D 
Sbjct: 1435 RLSVILDPNWNGKVCGLCGNNNG-DLKDDFTTRYSSVASGALEFGNSWK---TSQECSDT 1490

Query: 251  -----PVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLS 305
                 P    P   +     C E+L    F  C   VD  +Y + C ++ C C+      
Sbjct: 1491 VAQTFPCDSNPYCKAWAVRKC-EILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYL 1549

Query: 306  CVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECR---SPC----ADTCSNQ 358
              C  +A Y+  C+ A G+   WR P+ CP  C       ECR    PC    A TC +Q
Sbjct: 1550 GFCTAVAMYAEACS-AVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQ 1608

Query: 359  EHSRACEDHCVAGCF--CPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNC 416
               +      + GC+  CP+     D     CV +S+C+C YN    A G         C
Sbjct: 1609 LVGQKFSS-LLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGGVIEDNCGRTC 1667

Query: 417  TCSGGRWSCQE 427
             C  G+  C E
Sbjct: 1668 YCIAGQLECSE 1678



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 101/396 (25%), Positives = 147/396 (37%), Gaps = 64/396 (16%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNI--QLRRSQESAAPT------ 132
            C   GS    TFDG  + FPG C+++   +     ED++I  +LR        T      
Sbjct: 858  CKVEGS-SLTTFDGVKYNFPGNCHFLAVHN-----EDWSISVELRPCPSGQTGTCLNSVT 911

Query: 133  --------LSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEA--R 182
                    + + +   DG V   T   +   G+     +S    +   SSSY +VE    
Sbjct: 912  LLLNSSVPVDKYVFNSDGTV---TNDKIRNQGY----YYSDKIQIFNASSSYLQVETYFH 964

Query: 183  LGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMD 242
            + L +       L + +       T GLCG +N       + S N          L+K  
Sbjct: 965  VKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNI---------LEKTS 1015

Query: 243  DPTEQCQDPVPEPPRNCSTGFGI---------CEELLHGQ-LFSGCVALVDVGSYLEACR 292
                   + +  P  N S+   I         C  LL      + C  +V+   Y E C+
Sbjct: 1016 QAFANSWEMMSCPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECK 1075

Query: 293  QDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCA 352
            +  C CE++    C+C  L  Y + C         WR    C   CP+ + +      C 
Sbjct: 1076 KYTCTCENSQ--DCLCTILGNYVKACAEKETYIVGWR-TGLCEHSCPSGLVFKYNVKACN 1132

Query: 353  DTC-SNQEHSRAC--EDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
             +C S  E  R+C  ED  V GC CP+    ++ G   CV  S+C C  N     PG   
Sbjct: 1133 SSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEG--NCVLKSQCDCYINDEVMQPGKLI 1190

Query: 410  STDCTNCTCSGGRWSCQEVPCPGT---CSVLGGAHF 442
              D   C C  G   CQ +P   T   CS  GGA +
Sbjct: 1191 HIDDNKCVCRDGILLCQ-IPIDLTLQNCS--GGAEY 1223



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 48/160 (30%), Positives = 71/160 (44%), Gaps = 10/160 (6%)

Query: 1850 TSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTA 1909
            T  P+T P T      S    ++S     T  +  T T ++    TT     +TT A + 
Sbjct: 1730 TLGPLTEPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASE 1789

Query: 1910 RTTS-APTTRTTSASPASTTSGPGNTPSPVPTTSTISAPT----TSITSAPTTSTTSAPT 1964
             T+  A T R + A+PA    G G+TP      +T+S  T     SIT++P  S TS+ +
Sbjct: 1790 NTSERAGTPRVSGATPAV---GGGSTPGEAGPGATVSGSTGVSAGSITASPGASATSSES 1846

Query: 1965 --SSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSG 2002
              S TT       T A +S  TSS   S  +  +  +T+G
Sbjct: 1847 SKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAG 1886



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 54/178 (30%), Positives = 72/178 (40%), Gaps = 31/178 (17%)

Query: 1855 TAPSTPSGRAISPTQSTSSWQKSRTTTLVT---TSTTSTPQTSTTYAHTTSTTSAPTART 1911
            TAP T S  A+S T +T+        TLVT   ++  S P  +T+ + TT TT  P    
Sbjct: 1679 TAP-TNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLTEP 1737

Query: 1912 TSAPTTRTTSASPASTTSGPGNT--PSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTS 1969
             +   T  TS    ST+   G T   SP  T ++  A TT    A TT   S  TS    
Sbjct: 1738 FTTGITE-TSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERAG 1796

Query: 1970 APTTS-----------------------TTSAPTSSTTSSPQTSTTSAPTT-STTSGP 2003
             P  S                       +T     S T+SP  S TS+ ++ S T+GP
Sbjct: 1797 TPRVSGATPAVGGGSTPGEAGPGATVSGSTGVSAGSITASPGASATSSESSKSGTTGP 1854



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 43/165 (26%), Positives = 66/165 (40%), Gaps = 6/165 (3%)

Query: 1851 STPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTAR 1910
            ST V+A S  +    S T S SS  KS TT       T    +  T +   S  +  +  
Sbjct: 1825 STGVSAGSITASPGASATSSESS--KSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLG 1882

Query: 1911 TTSAPTTRTTSASPASTTSGPGNTPSPVP-TTSTISAPTTSITSAPTTSTTSAPTS---S 1966
            +T+   +  T+ +  + +S PG    P P +    S  TT   +  TT      TS    
Sbjct: 1883 STAGSDSEITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALG 1942

Query: 1967 TTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVP 2011
            +T     +TTSA + +T  +  T  T    T+ +  P  +P   P
Sbjct: 1943 STEGSVEATTSAGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGATP 1987



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 19/46 (41%), Positives = 28/46 (60%)

Query: 82  STWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQE 127
           STW    YK+F+G +F F   C Y F  HC  +  DFNI+++R+ +
Sbjct: 609 STWSKGAYKSFNGRIFFFESSCPYTFCRHCIESGGDFNIEIKRNND 654



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 36/122 (29%), Positives = 54/122 (44%), Gaps = 15/122 (12%)

Query: 1898 AHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTT 1957
            + T  T S     TT+A T  +T A+    T GP +T + +P  +T S+ TT  T  P T
Sbjct: 1677 SETAPTNSTFAVSTTTATTILSTGAAITLVTGGP-STAASIPAITTSSSETTGTTLGPLT 1735

Query: 1958 -------STTSAPTSSTTSAPTTSTTSAPT-------SSTTSSPQTSTTSAPTTSTTSGP 2003
                   + TS P  ST+     +   +PT       + TT     +TT A + +T+   
Sbjct: 1736 EPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA 1795

Query: 2004 GT 2005
            GT
Sbjct: 1796 GT 1797



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 10/165 (6%)

Query: 1849 VTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTS----TPQTSTTYAHTTSTT 1904
            +T++P  A +T S  + S T   S   K+  T+   TS+      T Q+  + A + S  
Sbjct: 1833 ITASP-GASATSSESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEI 1891

Query: 1905 SAPTARTTSAPTTRTTSASPASTTSGPGNTP--SPVPTTSTISAPTTSI---TSAPTTST 1959
            +A T+ T S+P  + T  SP S     G T     V TT      T+     T     +T
Sbjct: 1892 TAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEAT 1951

Query: 1960 TSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPG 2004
            TSA + +T     T  T    ++ + +P  S  + P    +S PG
Sbjct: 1952 TSAGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGATPGAPGSSTPG 1996



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 51/178 (28%), Positives = 70/178 (39%), Gaps = 20/178 (11%)

Query: 1849 VTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPT 1908
            +T+      S+P G+   P+  +       TT     +TT     +T+ A    +T    
Sbjct: 1891 ITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGA--LGSTEGSV 1948

Query: 1909 ARTTSAPTTRTTSASPASTTSGPGNTP-SPVPTTS---TISAPTTSITSAPTTSTTSAPT 1964
              TTSA +  T   S    T GPGNT  S  P  S   T  AP +S         TS   
Sbjct: 1949 EATTSAGSGNTAGTSGTGDT-GPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGK 2007

Query: 1965 SSTTSAPTTS---------TTSAPTSSTTSSPQTSTTSA--PTTSTTSG--PGTTPSP 2009
            S  +   + +         T +   +STTSSP +  T A   T  T SG  PGT  +P
Sbjct: 2008 SGKSGHDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTP 2065



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 27/63 (42%), Positives = 35/63 (55%), Gaps = 4/63 (6%)

Query: 1945 SAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPG 2004
            +APT S  +    STT+A T  +T A  T  T  P S+  S P  +T+S+ TT TT GP 
Sbjct: 1679 TAPTNSTFAV---STTTATTILSTGAAITLVTGGP-STAASIPAITTSSSETTGTTLGPL 1734

Query: 2005 TTP 2007
            T P
Sbjct: 1735 TEP 1737



 Score = 40.8 bits (94), Expect = 0.014
 Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 13/86 (15%)

Query: 1939 PTTSTISAPTTSITS-----APTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQT---- 1989
            PT ST +  TT+ T+     A  T  T  P S+  S P  +T+S+ T+ TT  P T    
Sbjct: 1681 PTNSTFAVSTTTATTILSTGAAITLVTGGP-STAASIPAITTSSSETTGTTLGPLTEPFT 1739

Query: 1990 ---STTSAPTTSTTSGPGTTPSPVPT 2012
               + TS P  ST+   G T    PT
Sbjct: 1740 TGITETSVPIISTSGNAGMTGVVSPT 1765



 Score = 39.7 bits (91), Expect = 0.030
 Identities = 51/193 (26%), Positives = 70/193 (36%), Gaps = 41/193 (21%)

Query: 1855 TAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTT-- 1912
            T PS       + +++TSS   S  T     ST  +    T  A T+ T S+P  + T  
Sbjct: 1852 TGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEIT--AKTSFTGSSPPGKLTRP 1909

Query: 1913 --------SAPTTR-----TTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTST 1959
                    S  TT      TT A+  +T+   G+T   V  T++  +  T+ TS   T  
Sbjct: 1910 SPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSG--TGD 1967

Query: 1960 TSAPTSSTTSAPTTS---TTSAPTSSTTSSPQTSTTS-------------------APTT 1997
            T    ++ +  P  S   T  AP SST        TS                      T
Sbjct: 1968 TGPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRT 2027

Query: 1998 STTSGPGTTPSPV 2010
             T S   TT SPV
Sbjct: 2028 PTVSAASTTSSPV 2040



 Score = 35.0 bits (79), Expect = 0.74
 Identities = 23/59 (38%), Positives = 33/59 (55%), Gaps = 4/59 (6%)

Query: 1953 SAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTT-SAPTTSTTSGPGTTPSPV 2010
            +APT ST +    STT+A T  +T A  +  T  P T+ +  A TTS++   GTT  P+
Sbjct: 1679 TAPTNSTFAV---STTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPL 1734



 Score = 33.5 bits (75), Expect = 2.2
 Identities = 39/126 (30%), Positives = 53/126 (42%), Gaps = 15/126 (11%)

Query: 1434 APGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSSSPAQTTPP 1493
            +PG    A G       D+G T   +   SG   +  + V     L  + + S A TT  
Sbjct: 1982 SPGATPGAPGSSTPGEADIGNTSFGKSGKSG---HDSLTVLNPAFLRRTPTVSAASTTSS 2038

Query: 1494 TTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTPSPPPVPATSTSSM 1553
              SK T+       A S+T  T+S S   T   PG ATS  K  S  S     ++ TS+ 
Sbjct: 2039 PVSKHTD-------AASATAVTISGSKPGTPGTPGGATSGGKITSGWS-----SSGTSTG 2086

Query: 1554 STTTPG 1559
            S+ TPG
Sbjct: 2087 SSNTPG 2092


>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
            sapiens]
          Length = 2134

 Score =  754 bits (1947), Expect = 0.0
 Identities = 458/1373 (33%), Positives = 654/1373 (47%), Gaps = 103/1373 (7%)

Query: 248  CQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGS-YLEACRQDLCFCEDTDLLSC 306
            C + V +    C  G   C +++ G  F  C  +  + + Y   C  + C   D    + 
Sbjct: 671  CPNAVGKSYEVCEDGIQHCNKII-GTYFEKCGKVAALSNDYKMICIDEYCQTRDK---TS 726

Query: 307  VCHTLAEYSRQCTHAG-GLPQDWRGPD--FC-PQKCPNNMQYHECRSPCADTCSNQEHSR 362
             C T +E SR C   G G  + WR      C  Q+CP    Y EC      TCSN    +
Sbjct: 727  TCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQ 786

Query: 363  ACEDHCVAGCFCPEGTVLDDIGQTG-CVPVSKCACVYNGAAYAPGATYSTDC-TNCTCSG 420
              E  CV+GC CPEG +LDDIG+ G CV  ++C C  +G  Y PG      C + CTC  
Sbjct: 787  DSE--CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQD 844

Query: 421  GRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGL 480
             +WSC E  CPG C V G +  +TFDG +Y   G+C ++     D   +++  ELR C  
Sbjct: 845  AKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVHNED---WSISVELRPCPS 900

Query: 481  TDSETCLKSVTLSLDGVQTV--VVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQ 538
              + TCL SVTL L+    V   V  + G V  ++I  Q    +  + IF  S+ ++  +
Sbjct: 901  GQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVE 960

Query: 539  TSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFN 598
            T   ++L +Q+VP MQL++ + P     T GLCG++N+   DDF +   ++E T+ AF N
Sbjct: 961  TYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFAN 1020

Query: 599  TFKTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCM 658
            +++  + CP    S      +S+E EK+A+  C  L D+ GP   CH  V P  Y+  C 
Sbjct: 1021 SWEMMS-CPKGNPS----SCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECK 1075

Query: 659  FDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQ 718
              TC CE S+DCLC  L +YV ACA K   + GWR G+C     +CP  + + Y+V  C 
Sbjct: 1076 KYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEH---SCPSGLVFKYNVKACN 1132

Query: 719  PTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHD 778
             +CRSLSE D +C V  +PVDGC CP   + ++ G CV  S C CY    ++  G+ +H 
Sbjct: 1133 SSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHI 1192

Query: 779  SGAICTCTHGKLSCIGGQAPAPV----CAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTC 834
                C C  G L C   Q P  +    C+    + DC +           ++C T ++  
Sbjct: 1193 DDNKCVCRDGILLC---QIPIDLTLQNCSGGAEYVDCSDPK---AQRRTNRTCSTRNIPV 1246

Query: 835  YSPQ--CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMW 892
            +     C  GC CP+G+V + +G C+   DCPC      Y  G    VGCN CTC    W
Sbjct: 1247 FDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSW 1306

Query: 893  RCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVP 952
             CT + C   C +YG+GH  TFDG+SYSF+G C+Y+ ++++CG ++ T   FR++TE+VP
Sbjct: 1307 SCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGT---FRILTESVP 1363

Query: 953  CGTTGTTCSKAIKIFLGGFELKLSHGKVEVIGTDESQEVP-----YTIRQMGIYLVVDTD 1007
            C   G TCS+ I +      + L  GKV  + + ES++       Y+I  +G+YL++   
Sbjct: 1364 CCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQ 1423

Query: 1008 IGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL 1067
             G++++WDK T + + L P + G+VCGLCGN +    +DF TR  SV    LEFGNSWK 
Sbjct: 1424 NGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT 1483

Query: 1068 SPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDACACD 1127
            S  C D +A   PC +NP+ K+WA ++C IL   TF  CH  V+P+ Y++ C+ +ACACD
Sbjct: 1484 SQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACD 1543

Query: 1128 SGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLR 1187
              G    FCTAVA YA+AC  VG+CVSWR P++CP++CDYYN  G+C WHY+PCG    +
Sbjct: 1544 MEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAK 1603

Query: 1188 TCRNPR-GDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRP 1246
            TC++   G     +  LEGCY KCP  AP  DE+ M+CV+          C        P
Sbjct: 1604 TCKDQLVGQKFSSL--LEGCYAKCPDSAPYLDENTMKCVSL-------SECSCFYNDVIP 1654

Query: 1247 GAVVPSDKNCQSCLCTERGVECTYKAE-----ACVCTYNGQRFHPGDVIYHTTDGTGGCI 1301
               V  D   ++C C    +EC+  A      A   T        G  I   T G     
Sbjct: 1655 AGGVIEDNCGRTCYCIAGQLECSETAPTNSTFAVSTTTATTILSTGAAITLVTGGPSTAA 1714

Query: 1302 SARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWP 1361
            S       + E       P T    T  + ++ P++ +S +    G  S      S    
Sbjct: 1715 SIPAITTSSSETTGTTLGPLTEPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAG 1774

Query: 1362 TTAG------------TSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDT 1409
            TT G            TS R   P  S   P V G           S PG          
Sbjct: 1775 TTGGVDAATTGAASENTSERAGTPRVSGETPAVGGG----------STPGEAGPGATVSG 1824

Query: 1410 LENLRAHGYRVCESPRSVECRAEDA-PGVPLRALGQRVQCSPDVGLTCRNREQASGLCYN 1468
               + A    +  SP +    +E +  G    ++G +       G T      + G+   
Sbjct: 1825 STGVSAGS--ITASPGASATSSESSKSGTTGPSVGGK------TGATSSEATSSEGMS-- 1874

Query: 1469 YQIRVQCCTPLACSTSSSPAQTTPPTTSKTTE-TRASGSSAPSSTPGTVSLSTARTTPAP 1527
              +  Q     A S S   A+T+   +S   + TR S  S    + GT       TT A 
Sbjct: 1875 -GVTGQSLGSTAGSDSEITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAA 1933

Query: 1528 GTATS------VKKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPST 1574
            G  TS           +T S        TS    T PG + VS  P ++  +T
Sbjct: 1934 GENTSGALGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGAT 1986



 Score =  126 bits (317), Expect = 2e-28
 Identities = 102/371 (27%), Positives = 157/371 (42%), Gaps = 31/371 (8%)

Query: 80   VCSTWGSFHYKTFDGDVFRFPGLCNYVFSE-HCGAAYEDFNIQLRRSQESAAP--TLSR- 135
            +C  +G  H +TFDG  + F GLC Y F E +CG     F I L  S        T SR 
Sbjct: 1316 ICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRI-LTESVPCCEDGLTCSRK 1374

Query: 136  --VLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDD 193
              V  +   +V+Q  K + + +        + +   I     Y  ++ + G++++W+ + 
Sbjct: 1375 IIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNT 1434

Query: 194  SLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMDDPTEQCQD- 250
             L + LD  +  K CGLCG+ NG  +  +  +  + +    +EFGN  K    +++C D 
Sbjct: 1435 RLSVILDPNWNGKVCGLCGNNNG-DLKDDFTTRYSSVASGALEFGNSWK---TSQECSDT 1490

Query: 251  -----PVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLS 305
                 P    P   +     C E+L    F  C   VD  +Y + C ++ C C+      
Sbjct: 1491 VAQTFPCDSNPYCKAWAVRKC-EILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYL 1549

Query: 306  CVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECR---SPC----ADTCSNQ 358
              C  +A Y+  C+ A G+   WR P+ CP  C       ECR    PC    A TC +Q
Sbjct: 1550 GFCTAVAMYAEACS-AVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQ 1608

Query: 359  EHSRACEDHCVAGCF--CPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNC 416
               +      + GC+  CP+     D     CV +S+C+C YN    A G         C
Sbjct: 1609 LVGQKFSS-LLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGGVIEDNCGRTC 1667

Query: 417  TCSGGRWSCQE 427
             C  G+  C E
Sbjct: 1668 YCIAGQLECSE 1678



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 101/396 (25%), Positives = 147/396 (37%), Gaps = 64/396 (16%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNI--QLRRSQESAAPT------ 132
            C   GS    TFDG  + FPG C+++   +     ED++I  +LR        T      
Sbjct: 858  CKVEGS-SLTTFDGVKYNFPGNCHFLAVHN-----EDWSISVELRPCPSGQTGTCLNSVT 911

Query: 133  --------LSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEA--R 182
                    + + +   DG V   T   +   G+     +S    +   SSSY +VE    
Sbjct: 912  LLLNSSVPVDKYVFNSDGTV---TNDKIRNQGY----YYSDKIQIFNASSSYLQVETYFH 964

Query: 183  LGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMD 242
            + L +       L + +       T GLCG +N       + S N          L+K  
Sbjct: 965  VKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNI---------LEKTS 1015

Query: 243  DPTEQCQDPVPEPPRNCSTGFGI---------CEELLHGQ-LFSGCVALVDVGSYLEACR 292
                   + +  P  N S+   I         C  LL      + C  +V+   Y E C+
Sbjct: 1016 QAFANSWEMMSCPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECK 1075

Query: 293  QDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCA 352
            +  C CE++    C+C  L  Y + C         WR    C   CP+ + +      C 
Sbjct: 1076 KYTCTCENSQ--DCLCTILGNYVKACAEKETYIVGWR-TGLCEHSCPSGLVFKYNVKACN 1132

Query: 353  DTC-SNQEHSRAC--EDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
             +C S  E  R+C  ED  V GC CP+    ++ G   CV  S+C C  N     PG   
Sbjct: 1133 SSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEG--NCVLKSQCDCYINDEVMQPGKLI 1190

Query: 410  STDCTNCTCSGGRWSCQEVPCPGT---CSVLGGAHF 442
              D   C C  G   CQ +P   T   CS  GGA +
Sbjct: 1191 HIDDNKCVCRDGILLCQ-IPIDLTLQNCS--GGAEY 1223



 Score = 51.6 bits (122), Expect = 8e-06
 Identities = 47/160 (29%), Positives = 70/160 (43%), Gaps = 10/160 (6%)

Query: 1850 TSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTA 1909
            T  P+T P T      S    ++S     T  +  T T ++    TT     +TT A + 
Sbjct: 1730 TLGPLTEPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASE 1789

Query: 1910 RTTS-APTTRTTSASPASTTSGPGNTPSPVPTTSTISAPT----TSITSAPTTSTTSAPT 1964
             T+  A T R +  +PA    G G+TP      +T+S  T     SIT++P  S TS+ +
Sbjct: 1790 NTSERAGTPRVSGETPAV---GGGSTPGEAGPGATVSGSTGVSAGSITASPGASATSSES 1846

Query: 1965 --SSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSG 2002
              S TT       T A +S  TSS   S  +  +  +T+G
Sbjct: 1847 SKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAG 1886



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 54/178 (30%), Positives = 72/178 (40%), Gaps = 31/178 (17%)

Query: 1855 TAPSTPSGRAISPTQSTSSWQKSRTTTLVT---TSTTSTPQTSTTYAHTTSTTSAPTART 1911
            TAP T S  A+S T +T+        TLVT   ++  S P  +T+ + TT TT  P    
Sbjct: 1679 TAP-TNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLTEP 1737

Query: 1912 TSAPTTRTTSASPASTTSGPGNT--PSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTS 1969
             +   T  TS    ST+   G T   SP  T ++  A TT    A TT   S  TS    
Sbjct: 1738 FTTGITE-TSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERAG 1796

Query: 1970 APTTS-----------------------TTSAPTSSTTSSPQTSTTSAPTT-STTSGP 2003
             P  S                       +T     S T+SP  S TS+ ++ S T+GP
Sbjct: 1797 TPRVSGETPAVGGGSTPGEAGPGATVSGSTGVSAGSITASPGASATSSESSKSGTTGP 1854



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 43/165 (26%), Positives = 66/165 (40%), Gaps = 6/165 (3%)

Query: 1851 STPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTAR 1910
            ST V+A S  +    S T S SS  KS TT       T    +  T +   S  +  +  
Sbjct: 1825 STGVSAGSITASPGASATSSESS--KSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLG 1882

Query: 1911 TTSAPTTRTTSASPASTTSGPGNTPSPVP-TTSTISAPTTSITSAPTTSTTSAPTS---S 1966
            +T+   +  T+ +  + +S PG    P P +    S  TT   +  TT      TS    
Sbjct: 1883 STAGSDSEITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALG 1942

Query: 1967 TTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVP 2011
            +T     +TTSA + +T  +  T  T    T+ +  P  +P   P
Sbjct: 1943 STEGSVEATTSAGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGATP 1987



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 19/46 (41%), Positives = 28/46 (60%)

Query: 82  STWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQE 127
           STW    YK+F+G +F F   C Y F  HC  +  DFNI+++R+ +
Sbjct: 609 STWSKGAYKSFNGRIFFFESSCPYTFCRHCIESGGDFNIEIKRNND 654



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 36/122 (29%), Positives = 54/122 (44%), Gaps = 15/122 (12%)

Query: 1898 AHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTT 1957
            + T  T S     TT+A T  +T A+    T GP +T + +P  +T S+ TT  T  P T
Sbjct: 1677 SETAPTNSTFAVSTTTATTILSTGAAITLVTGGP-STAASIPAITTSSSETTGTTLGPLT 1735

Query: 1958 -------STTSAPTSSTTSAPTTSTTSAPT-------SSTTSSPQTSTTSAPTTSTTSGP 2003
                   + TS P  ST+     +   +PT       + TT     +TT A + +T+   
Sbjct: 1736 EPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA 1795

Query: 2004 GT 2005
            GT
Sbjct: 1796 GT 1797



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 10/165 (6%)

Query: 1849 VTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTS----TPQTSTTYAHTTSTT 1904
            +T++P  A +T S  + S T   S   K+  T+   TS+      T Q+  + A + S  
Sbjct: 1833 ITASP-GASATSSESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEI 1891

Query: 1905 SAPTARTTSAPTTRTTSASPASTTSGPGNTP--SPVPTTSTISAPTTSI---TSAPTTST 1959
            +A T+ T S+P  + T  SP S     G T     V TT      T+     T     +T
Sbjct: 1892 TAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEAT 1951

Query: 1960 TSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPG 2004
            TSA + +T     T  T    ++ + +P  S  + P    +S PG
Sbjct: 1952 TSAGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGATPGAPGSSTPG 1996



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 51/178 (28%), Positives = 70/178 (39%), Gaps = 20/178 (11%)

Query: 1849 VTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPT 1908
            +T+      S+P G+   P+  +       TT     +TT     +T+ A    +T    
Sbjct: 1891 ITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGA--LGSTEGSV 1948

Query: 1909 ARTTSAPTTRTTSASPASTTSGPGNTP-SPVPTTS---TISAPTTSITSAPTTSTTSAPT 1964
              TTSA +  T   S    T GPGNT  S  P  S   T  AP +S         TS   
Sbjct: 1949 EATTSAGSGNTAGTSGTGDT-GPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGK 2007

Query: 1965 SSTTSAPTTS---------TTSAPTSSTTSSPQTSTTSA--PTTSTTSG--PGTTPSP 2009
            S  +   + +         T +   +STTSSP +  T A   T  T SG  PGT  +P
Sbjct: 2008 SGKSGHDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTP 2065



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 27/63 (42%), Positives = 35/63 (55%), Gaps = 4/63 (6%)

Query: 1945 SAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPG 2004
            +APT S  +    STT+A T  +T A  T  T  P S+  S P  +T+S+ TT TT GP 
Sbjct: 1679 TAPTNSTFAV---STTTATTILSTGAAITLVTGGP-STAASIPAITTSSSETTGTTLGPL 1734

Query: 2005 TTP 2007
            T P
Sbjct: 1735 TEP 1737



 Score = 40.8 bits (94), Expect = 0.014
 Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 13/86 (15%)

Query: 1939 PTTSTISAPTTSITS-----APTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQT---- 1989
            PT ST +  TT+ T+     A  T  T  P S+  S P  +T+S+ T+ TT  P T    
Sbjct: 1681 PTNSTFAVSTTTATTILSTGAAITLVTGGP-STAASIPAITTSSSETTGTTLGPLTEPFT 1739

Query: 1990 ---STTSAPTTSTTSGPGTTPSPVPT 2012
               + TS P  ST+   G T    PT
Sbjct: 1740 TGITETSVPIISTSGNAGMTGVVSPT 1765



 Score = 39.7 bits (91), Expect = 0.030
 Identities = 51/193 (26%), Positives = 70/193 (36%), Gaps = 41/193 (21%)

Query: 1855 TAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTT-- 1912
            T PS       + +++TSS   S  T     ST  +    T  A T+ T S+P  + T  
Sbjct: 1852 TGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEIT--AKTSFTGSSPPGKLTRP 1909

Query: 1913 --------SAPTTR-----TTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTST 1959
                    S  TT      TT A+  +T+   G+T   V  T++  +  T+ TS   T  
Sbjct: 1910 SPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSG--TGD 1967

Query: 1960 TSAPTSSTTSAPTTS---TTSAPTSSTTSSPQTSTTS-------------------APTT 1997
            T    ++ +  P  S   T  AP SST        TS                      T
Sbjct: 1968 TGPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRT 2027

Query: 1998 STTSGPGTTPSPV 2010
             T S   TT SPV
Sbjct: 2028 PTVSAASTTSSPV 2040



 Score = 38.5 bits (88), Expect = 0.067
 Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 17/167 (10%)

Query: 1852 TPVTAPSTPS-GRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTS--TTSAPT 1908
            TP  +  TP+ G   +P ++      S +T +   S T++P  S T + ++   TT    
Sbjct: 1797 TPRVSGETPAVGGGSTPGEAGPGATVSGSTGVSAGSITASPGASATSSESSKSGTTGPSV 1856

Query: 1909 ARTTSAPTTRTTSASPASTTSGP--GNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSS 1966
               T A ++  TS+   S  +G   G+T           A + S  +A T+ T S+P   
Sbjct: 1857 GGKTGATSSEATSSEGMSGVTGQSLGST-----------AGSDSEITAKTSFTGSSPPGK 1905

Query: 1967 TTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
             T  P+  +    +  TT     +TT A   +T+   G+T   V  T
Sbjct: 1906 LTR-PSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEAT 1951



 Score = 35.0 bits (79), Expect = 0.74
 Identities = 23/59 (38%), Positives = 33/59 (55%), Gaps = 4/59 (6%)

Query: 1953 SAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTT-SAPTTSTTSGPGTTPSPV 2010
            +APT ST +    STT+A T  +T A  +  T  P T+ +  A TTS++   GTT  P+
Sbjct: 1679 TAPTNSTFAV---STTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPL 1734



 Score = 32.3 bits (72), Expect = 4.8
 Identities = 38/126 (30%), Positives = 53/126 (42%), Gaps = 15/126 (11%)

Query: 1434 APGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSSSPAQTTPP 1493
            +PG    A G       D+G T   +   SG   +  + V     L  + + S A TT  
Sbjct: 1982 SPGATPGAPGSSTPGEADIGNTSFGKSGKSG---HDSLTVLNPAFLRRTPTVSAASTTSS 2038

Query: 1494 TTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTPSPPPVPATSTSSM 1553
              SK T+       A S+T  T+S S   T   PG ATS  K  S  S     ++ TS+ 
Sbjct: 2039 PVSKHTD-------AASATAVTISGSKPGTPGTPGGATSGGKITSGWS-----SSGTSTG 2086

Query: 1554 STTTPG 1559
            ++ TPG
Sbjct: 2087 ASNTPG 2092


>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2852

 Score =  612 bits (1577), Expect = e-174
 Identities = 381/1126 (33%), Positives = 548/1126 (48%), Gaps = 65/1126 (5%)

Query: 80   VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQE--SAAPTLSRV- 136
            +C  WG  H +TFDG  +   G  +Y          + F+IQ+    +  S+  T SR  
Sbjct: 78   ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137

Query: 137  -LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSL 195
             L  V    I L K  V   G  V LP       +QQ + Y  V  +    L W+   ++
Sbjct: 138  SLFFVGEQEIHLAK-EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAV 196

Query: 196  LLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL---QKMDDPTEQCQD 250
             +++  +    T GLCG+ N  P   +L++ + KLT   +EF +    Q  + P      
Sbjct: 197  YIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255

Query: 251  PVPEPP---RNCSTGFGI---CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304
             +P PP   +N  T  G+   CE LL    F  C A V    +  +C  DLC  +    +
Sbjct: 256  SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLC--QSMGDV 312

Query: 305  SCVCHTLAEYSRQCTHAGGLPQDWRGP-DFCPQKCPNN-MQYHECRSPCADTCSNQEHSR 362
            +  C  LAEY+R C  AG   Q WR     C   C      Y+EC + C  +C  +    
Sbjct: 313  ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCV 372

Query: 363  ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGR 422
              E  CV GC+CP G + +D    GCV  ++C C ++G  Y PG+    DC  CTC+ G+
Sbjct: 373  DSEIACVDGCYCPNGLIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGK 429

Query: 423  WSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD 482
            W C    CP  CSV G  HF+TFDG++YT    C Y+L K   S  FTV  +   CGL  
Sbjct: 430  WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQ 489

Query: 483  SETCLKSVTLSL-DGVQTVVVIKASGEVFLNQIYTQLPISAANV-TIFRPSTFFIIAQTS 540
               C++SV++ L    +  V +  +G+V L   Y  +P    +   I R S+ F+  +T+
Sbjct: 490  DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 549

Query: 541  LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600
            +G+++ L     ++L++Q+  +    T GLCG FN    DDF +  GV E+T   F N++
Sbjct: 550  VGVRV-LYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSW 608

Query: 601  KTQAAC-PNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMF 659
            KT +AC P +  S  DPC + ++   Y+   CS LT     F  C A + P  Y+  C  
Sbjct: 609  KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRR 666

Query: 660  DTCNCERSEDCLCAALSSYVHACAAKGVQLG-GWRDGVCTKPMTTCPKSMTYHYHVSTCQ 718
            D C C   + CLCA L+ Y H C   G+ +    R   C     +C  S  Y   V+ C 
Sbjct: 667  DACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACA---LSCEASKEYSPCVAPCG 721

Query: 719  PTCRSLSEGDITCSVGFIP-------VDGCICPKGTFLDDTGK-CVQASNCPCYHRGSMI 770
             TC+ L+  +  C V           V+GC CP  T+LD     CV  + C C+ +G   
Sbjct: 722  RTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780

Query: 771  PNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPG---DTGAGCQKSC 827
            P G+S   S   C C  G +SC   +APA  C A  VF +C +            C++  
Sbjct: 781  PPGDSDIPSLGHCHCKDGVMSC-DSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQL 839

Query: 828  HTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTC 887
              L ++   P C+ GC CP GL+  G+  C   E+CPC      Y  G  +   C+TC C
Sbjct: 840  LNLSVSARGP-CLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVC 897

Query: 888  DSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVV 947
                ++CT  PC +TC  YGD HY TFDG  + F G C+  LV      K ++  SF V+
Sbjct: 898  QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVI 951

Query: 948  TENVPCGTTGTTCSKAIKIFLGG----FELKLSHGKVEVIGTDESQEVPYTIRQMGIYLV 1003
             ENV C ++G  C K I I +G     F+    +   E    D+ QEV +T R     LV
Sbjct: 952  VENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESF-LDDKQEV-HTWRVGFFTLV 1009

Query: 1004 VDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGN 1063
                  + LLWD++T++ +   P+++G++ GLCGNFD   +N+  T     + +  EFG+
Sbjct: 1010 HFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGS 1069

Query: 1064 SWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDA 1123
            SW  +  CPD L P+D C  NP R+ +A+K+CSIL    F  CH  V+   +Y  C+ D 
Sbjct: 1070 SWA-AVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1128

Query: 1124 CACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYN 1169
            C C  GGDCECFC +V+AYA  C + G+ V WRTP +CP  CD++N
Sbjct: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174



 Score =  231 bits (590), Expect = 4e-60
 Identities = 152/486 (31%), Positives = 221/486 (45%), Gaps = 62/486 (12%)

Query: 821  AGCQKSCHTLDMTCYSPQ--CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTI 878
            A C  SCH    +C   +  CV GC CP+GL+ + +GGC+   +CPC  +   Y  G  +
Sbjct: 359  ACCPASCHPR-ASCVDSEIACVDGCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVV 416

Query: 879  RVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKD 938
            +  CNTCTC S  W C+   C A C+V GD H+ TFDG+ Y+F   C+Y L ++   G  
Sbjct: 417  KEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG-- 474

Query: 939  STQDSFRVVTENVPCGTTGT-TCSKAIKIFL------------GGFELKLSHGKVEVIGT 985
                +F V  +N PCG      C +++ + L             G  L     K+    T
Sbjct: 475  ----TFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYT 530

Query: 986  DESQEVPYTIRQMGIYLVVDTDIGLVLLWDKK-TSIFINLSPEFKGRVCGLCGNFDDIAV 1044
            D++ E+    R   ++L V T++G+ +L+D++   +++ +   +     GLCG F+    
Sbjct: 531  DDAFEIR---RLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQ 587

Query: 1045 NDFATRSRSVVGDVLEFGNSWKLSPSCPDALA--PKDPCTANPFRKSWAQKQCSILHGPT 1102
            +DF +           FGNSWK   +C   ++  P DPC  +    S++ + CS+L G  
Sbjct: 588  DDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM 647

Query: 1103 FAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTP-SIC 1161
            FA C A + P  Y+E C  DAC C       C C  +A YA  C   GL V +R     C
Sbjct: 648  FAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPAC 703

Query: 1162 PLFCDYYNPEGQCEWHYQPCGVPCLRTCRN---------PRGDCLRDVWGLEGCYPKCPP 1212
             L C+           Y PC  PC RTC++           GD L     +EGC   CPP
Sbjct: 704  ALSCE-------ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPP 754

Query: 1213 EAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPG-AVVPSDKNCQSCLCTERGVECTYK 1271
            +    D     CV     P     CH  G  Y PG + +PS  +C    C +  + C  +
Sbjct: 755  DT-YLDTQADLCV-----PRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSR 805

Query: 1272 AEACVC 1277
            A A  C
Sbjct: 806  APAAAC 811



 Score =  184 bits (468), Expect = 6e-46
 Identities = 136/449 (30%), Positives = 201/449 (44%), Gaps = 68/449 (15%)

Query: 887  CDSRMWRCTDDPCL----------ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGG 936
            CD R +  T   C           + C  +G  H  TFDG  Y  +G   YTLV  H   
Sbjct: 53   CDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRH--- 109

Query: 937  KDSTQDSFRVVTENVP-CGTTGTTCSKAIKIFLGGFE-----LKLSHGKVEVIGTDESQE 990
             +    SF +   N P CG++  TCS+A+ +F  G +      +++HG + V       +
Sbjct: 110  -EPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRV-------Q 161

Query: 991  VPYT-----IRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVN 1045
            +P+      ++Q+  Y++V       L WD  ++++I +SPE  G   GLCGN +    +
Sbjct: 162  LPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221

Query: 1046 DFATRSRSVVGDVLEFGNSWKLS-----PSCPDALAPKDPCTA-NPFRKSWAQKQCSILH 1099
            D  T S  +  DV+EF +SW+       P    +  P+ PC   NP       +QC  L 
Sbjct: 222  DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL 281

Query: 1100 GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTP 1158
             P F ACHA+V P  +  +C +D C   S GD   +C A+A YA+AC + G  +  WRT 
Sbjct: 282  RPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 339

Query: 1159 -SICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCL-RDVWGLEGCYPKCPPEAPI 1216
               C + C       +  + Y  C   C  +C +PR  C+  ++  ++GCY  CP    I
Sbjct: 340  LRQCTVHCK------EKAFTYNECIACCPASC-HPRASCVDSEIACVDGCY--CP-NGLI 389

Query: 1217 FDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACV 1276
            F++      A CP       C  HG  Y PG+VV  D  C +C CT    EC+       
Sbjct: 390  FEDGGCVAPAECP-------CEFHGTLYPPGSVVKED--CNTCTCTSGKWECSTAVCPAE 440

Query: 1277 CTYNGQRFHPGDVIYHTTDGTGGCISARC 1305
            C+        GD+ + T DG      A C
Sbjct: 441  CSVT------GDIHFTTFDGRRYTFPATC 463



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 69/285 (24%), Positives = 110/285 (38%), Gaps = 18/285 (6%)

Query: 143  VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELDTK 202
            V I      V V+  PV  P S+ G  I+ +     +     + + W H   L++   +K
Sbjct: 2107 VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASK 2166

Query: 203  YAN-KTCGLCGDFNGMPVVSELLSHNTKL----TPMEFGNLQKMDDPTEQCQDPVPEPPR 257
             +  +  GLCG  +G       L   + +     P  F +  ++             P  
Sbjct: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226

Query: 258  NCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQ 317
              +T    C  ++  + FS C   V   S+ E       +  DT  +   C  L  Y   
Sbjct: 2227 CATTDCSPCLRMVSNRTFSACHRFVPPESFCEL------WIRDTKYVQQPCVALTVYVAM 2280

Query: 318  CTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD--TCSNQEHSRACEDHCVA---GC 372
            C H   +  +WR  D+CP  C ++  Y  C + C    TC +        +HC     GC
Sbjct: 2281 C-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2339

Query: 373  FCPEGTVLDDIGQTGCVPVSKCACVYN-GAAYAPGATYSTDCTNC 416
             C EGT+L       C+P +KCAC  + G   A G T+++  + C
Sbjct: 2340 VCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2384



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 79/334 (23%), Positives = 126/334 (37%), Gaps = 48/334 (14%)

Query: 875  GQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHC 934
            G  +RVG + C     +W C        C+++ D  ++TFDG   +   +  Y L Q+  
Sbjct: 2019 GLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSP- 2069

Query: 935  GGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGKVEVIGTDESQEV--- 991
              +  T       + N+        C   + +     ++ +     +V  T + Q V   
Sbjct: 2070 -DEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKV--TVDLQPVWPP 2126

Query: 992  ----PYTIRQMGIYLVVDTDIGLVLLWDKKTSIFI-NLSPEFKGRVCGLCGNFDDIAVND 1046
                 + I   G   ++ T   + + W   + + I   S   K +  GLCG  D  A ND
Sbjct: 2127 VSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAAND 2186

Query: 1047 FATRSRSVVG---DVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCS----ILH 1099
               +  SVVG   D   F +SW++    P +L         P   S A   CS    ++ 
Sbjct: 2187 LTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQTRFRP--DSCATTDCSPCLRMVS 2240

Query: 1100 GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPS 1159
              TF+ACH  V P  + E  + D             C A+  Y   CH+  +C+ WR   
Sbjct: 2241 NRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSD 2294

Query: 1160 ICPLFCDYYNPEGQCEWHYQPCGVPC--LRTCRN 1191
             CP  C         +  YQ C   C   +TC++
Sbjct: 2295 YCPFLC-------SSDSTYQACVTACEPPKTCQD 2321



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 148/661 (22%), Positives = 225/661 (34%), Gaps = 108/661 (16%)

Query: 386  TGCVPVSKCACV-----------YNGAAYAPGATYSTDCTNCTCS---GGRWSCQEVPCP 431
            T CVP+++  CV            N + + P       C     +   GG   C    C 
Sbjct: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECA 2036

Query: 432  GTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD---SETCLK 488
              CS+     F TFDG    +  +  Y+L++  D      + + +   L        CL 
Sbjct: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096

Query: 489  SVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQ 548
             + ++    Q V + + + +V ++      P+S     I      ++I   S    + +Q
Sbjct: 2097 MLNMTHLAHQ-VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQ 2152

Query: 549  LVPTMQLFMQLAPKL-RGQTCGLCGNFNSIQADDFRTLSGVVEATA---AAFFNTFKTQA 604
             + +  L +  A K  + Q  GLCG  +   A+D     G V   A   A F ++++  +
Sbjct: 2153 WLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPS 2212

Query: 605  ACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNC 664
            +  ++  +   P S +  +        S  T     F  CH  V P ++    + DT   
Sbjct: 2213 SLTSVGQTRFRPDSCATTDCSPCLRMVSNRT-----FSACHRFVPPESFCELWIRDTKYV 2267

Query: 665  ERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQP--TCR 722
            ++     C AL+ YV  C    V +   R   C      C    TY   V+ C+P  TC+
Sbjct: 2268 QQP----CVALTVYVAMCHKFHVCIEWRRSDYCP---FLCSSDSTYQACVTACEPPKTCQ 2320

Query: 723  SLSEGDITCSVGFIPVDGCICPKGTFLD--DTGKCVQASNCPCY-HRGSMIPNGESVHDS 779
                G +      +  +GC+C +GT L    +  C+  + C C    G     GE+ + S
Sbjct: 2321 DGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSS 2380

Query: 780  GAICTCTHGKLSCIGGQAPAPV---CAAPM---------VFFDCRNATPGDTGAGC---Q 824
             + C C H    C       PV   C +P          V        P   G  C   Q
Sbjct: 2381 LSGC-CQH---QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQ 2436

Query: 825  KSCHTLDMTC------------------YSPQC---------VPGCVCPDGLVADGEG-G 856
              C  L  TC                  YS +C         VP C     L+    G  
Sbjct: 2437 TLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDS 2496

Query: 857  CITA-----EDCP-----CVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPC---LATC 903
            C T+      DCP     C   EA      T  + C    C    +RC    C    A  
Sbjct: 2497 CCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALV 2556

Query: 904  AVYGDGHYLTFDGQSYSFNGDCEYTLVQN-HCGGKDSTQDSFRVVTENVPCGTTGTTCSK 962
             V+       +     S   DC+   V   H   K    + F    ENV CG     C K
Sbjct: 2557 EVWSPDRCCPYK----SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENV-CGCAKYECVK 2611

Query: 963  A 963
            A
Sbjct: 2612 A 2612



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 106/450 (23%), Positives = 150/450 (33%), Gaps = 73/450 (16%)

Query: 1174 CEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCV--ATCPTP 1231
            CEW Y  C  PC +TCR+PR    RDV  +EGC P C P   + DE   +CV    C  P
Sbjct: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVC-PTPQVLDEVTQRCVYLEDCVEP 1394

Query: 1232 PLPPRCHVHGKSYRP---GAVVPSDKNCQ------------------SCLCTERGVECTY 1270
             +       G    P   G   PSD+  Q                  + L T      T 
Sbjct: 1395 AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTA 1454

Query: 1271 KAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFS 1330
              E  V     Q      +    +    G   +      T      P +P +   P    
Sbjct: 1455 TEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQ 1514

Query: 1331 FSTPPLVVSSTHTP--------SNGPSSAHTGPPSSAWP------TTAG-------TSPR 1369
              TP +V  +  T         S   + +   PP+  +P      T  G       T+P 
Sbjct: 1515 TPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPP 1574

Query: 1370 TRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCES---PRS 1426
                TAS S  PV       SP      P   T SG    +  L     +V      P+ 
Sbjct: 1575 QPSLTASPSSRPVA------SPGAISRSP---TSSGSHKAV--LTPAVTKVISRTGVPQP 1623

Query: 1427 VECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLA--CSTS 1484
             + ++  +P  PL   G   +  P   L  R+ E             Q   P+    S  
Sbjct: 1624 TQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQ---PMGSPASPQ 1680

Query: 1485 SSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTA----RTTPAPGTATSVKKTFSTP 1540
              P  + PP  ++ T       + P  TP   SLSTA      TP     ++      + 
Sbjct: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740

Query: 1541 SPP----PVPATSTSS-MSTTTPGTSVVSS 1565
             PP    P+    TS+ ++T  P  SV+++
Sbjct: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITT 1770



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 51/186 (27%), Positives = 71/186 (38%), Gaps = 33/186 (17%)

Query: 1848 PVTST--PVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYA------H 1899
            PVT+T  PV +P         PTQ+T       T + +    T +P +    A      H
Sbjct: 1451 PVTATEEPVVSPG--------PTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1502

Query: 1900 TTSTTSAPTARTTSAP--------TTRTT---SASPASTTSGPGNTPSPVPTTSTISAPT 1948
            T  ++S P A  T  P        TTR T   + SP  T S   + P+P     T +   
Sbjct: 1503 TPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSS-RSPPAPRFPLMTKAVTV 1561

Query: 1949 TSITSAPTTSTTSAP--TSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTT 2006
                S P  +T   P  T+S +S P  S  +   S T+S    +  +   T   S  G  
Sbjct: 1562 RGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV- 1620

Query: 2007 PSPVPT 2012
              P PT
Sbjct: 1621 --PQPT 1624



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 73/344 (21%), Positives = 117/344 (34%), Gaps = 47/344 (13%)

Query: 1687 VATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPT------ATSVTQGTHTTPVT 1740
            VA   PTP       +TT  T +  A +   T +SR  P         +VT   H +   
Sbjct: 1511 VALQTPTPGMVSGAMETTRVTVI-FAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPV 1569

Query: 1741 RNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRL---------- 1790
            R   P+ + T       PS  P         +   SG         +T++          
Sbjct: 1570 RTTPPQPSLTA-----SPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPT 1624

Query: 1791 QCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVT 1850
            Q ++ S P   +   G   +      L  R+       ++ L+ E        P G P +
Sbjct: 1625 QAQSASSPSTPLTVAGTAAEQVPVSPLATRS------LEIVLSTEKGEAGHSQPMGSPAS 1678

Query: 1851 STPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTAR 1910
              P   PS P              + ++ TT+ T S    P+T    + +T+T       
Sbjct: 1679 PQPHPLPSAPP-------------RPAQHTTMATRSPALPPETPAAASLSTATDGLAATP 1725

Query: 1911 TTSAPTTRTTSASPASTTSG-PGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTS 1969
              S  +TR     P+   SG P +T  P+    T +   T    A   +T   P ++T  
Sbjct: 1726 FMSLESTR-----PSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLP 1780

Query: 1970 APTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
            A T S     T +  +     T  AP  + T+      + +PT+
Sbjct: 1781 AQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTS 1824



 Score = 39.3 bits (90), Expect = 0.039
 Identities = 47/167 (28%), Positives = 64/167 (38%), Gaps = 21/167 (12%)

Query: 1850 TSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTA 1909
            TS PV  P   +    +P Q  ++   ++T + V   T +    + T AH  +  + P A
Sbjct: 1754 TSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPA----AMTQAHPPTHIAPPAA 1809

Query: 1910 RTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTS--APTSST 1967
             T  AP     +  P S     G  P    T S +S         P  STT   A  S  
Sbjct: 1810 GT--APGLLLGATLPTS-----GVLPVAEGTASMVSV-------VPRKSTTGKVAILSKQ 1855

Query: 1968 TSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSG-PGTTPSPVPTT 2013
             S PT+   SA    T  +P TS    P  +   G    T  PVPT+
Sbjct: 1856 VSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTS 1902



 Score = 35.8 bits (81), Expect = 0.44
 Identities = 40/185 (21%), Positives = 60/185 (32%), Gaps = 35/185 (18%)

Query: 1855 TAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST-----TSAPTA 1909
            T P +      S  +   S +  RT T     T + P T+      T+T     +  PT 
Sbjct: 1407 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQ 1466

Query: 1910 RTTSAPTTRTTSASPASTTSGPG------------NTPSPVPTTSTISAPTTSITSAPTT 1957
             T   P   T S  PA  T  P             +TP        +  PT  + S    
Sbjct: 1467 TTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAME 1526

Query: 1958 STTSAPTSSTTSAPTTSTTSAPTSS------------------TTSSPQTSTTSAPTTST 1999
            +T      + +   T S+ S P                      T+ PQ S T++P++  
Sbjct: 1527 TTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRP 1586

Query: 2000 TSGPG 2004
             + PG
Sbjct: 1587 VASPG 1591



 Score = 35.8 bits (81), Expect = 0.44
 Identities = 33/129 (25%), Positives = 42/129 (32%), Gaps = 16/129 (12%)

Query: 1885 TSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTI 1944
            T +   PQ S     T      PT R    P    T+A     T+      SP PT +T+
Sbjct: 1416 TPSDEEPQLSQESPRT------PTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTL 1469

Query: 1945 SAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPG 2004
              P     S      T +P S   +A   +    P SS          S P    T  PG
Sbjct: 1470 QQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESS----------SLPVALQTPTPG 1519

Query: 2005 TTPSPVPTT 2013
                 + TT
Sbjct: 1520 MVSGAMETT 1528



 Score = 34.7 bits (78), Expect = 0.97
 Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 3/54 (5%)

Query: 343  QYHECRSPCADTCSNQEHSRACEDHCVAGC--FCPEGTVLDDIGQTGCVPVSKC 394
            +Y  C SPC  TC +   +   +   V GC   CP   VLD++ Q  CV +  C
Sbjct: 1339 RYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQR-CVYLEDC 1391



 Score = 32.7 bits (73), Expect = 3.7
 Identities = 31/104 (29%), Positives = 45/104 (43%), Gaps = 16/104 (15%)

Query: 1477 TPLACSTSSSPAQTT---PPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSV 1533
            TP     S+ P+Q     PP TS        G+SAP +TPG  +  +  TTP    AT++
Sbjct: 1724 TPFMSLESTRPSQLLSGLPPDTS--LPLAKVGTSAPVATPGPKA--SVITTPLQPQATTL 1779

Query: 1534 KKTFSTPSPPPVPATSTSS---------MSTTTPGTSVVSSKPT 1568
                 +P  P  PA  T +          + T PG  + ++ PT
Sbjct: 1780 PAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPT 1823



 Score = 31.6 bits (70), Expect = 8.2
 Identities = 46/182 (25%), Positives = 60/182 (32%), Gaps = 34/182 (18%)

Query: 1848 PVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAP 1907
            P T     A  T  G  +  T  TS        T    S      T+   A  +   S P
Sbjct: 1800 PPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLP 1859

Query: 1908 TARTTSA---PTTRTTSASP------ASTTSGPGNTPSPVPTTSTIS------APTTSI- 1951
            T+   SA   PT  T + S       A        T  PVPT+  +S      AP  S+ 
Sbjct: 1860 TSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSML 1919

Query: 1952 -----------TSA-------PTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTS 1993
                       TSA       P    T+ P+  +  A +     A   +TT+   TSTT 
Sbjct: 1920 VLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTC 1979

Query: 1994 AP 1995
             P
Sbjct: 1980 VP 1981


>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2924

 Score =  612 bits (1577), Expect = e-174
 Identities = 381/1126 (33%), Positives = 548/1126 (48%), Gaps = 65/1126 (5%)

Query: 80   VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQE--SAAPTLSRV- 136
            +C  WG  H +TFDG  +   G  +Y          + F+IQ+    +  S+  T SR  
Sbjct: 150  ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 209

Query: 137  -LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSL 195
             L  V    I L K  V   G  V LP       +QQ + Y  V  +    L W+   ++
Sbjct: 210  SLFFVGEQEIHLAK-EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAV 268

Query: 196  LLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL---QKMDDPTEQCQD 250
             +++  +    T GLCG+ N  P   +L++ + KLT   +EF +    Q  + P      
Sbjct: 269  YIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327

Query: 251  PVPEPP---RNCSTGFGI---CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304
             +P PP   +N  T  G+   CE LL    F  C A V    +  +C  DLC  +    +
Sbjct: 328  SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLC--QSMGDV 384

Query: 305  SCVCHTLAEYSRQCTHAGGLPQDWRGP-DFCPQKCPNN-MQYHECRSPCADTCSNQEHSR 362
            +  C  LAEY+R C  AG   Q WR     C   C      Y+EC + C  +C  +    
Sbjct: 385  ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCV 444

Query: 363  ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGR 422
              E  CV GC+CP G + +D    GCV  ++C C ++G  Y PG+    DC  CTC+ G+
Sbjct: 445  DSEIACVDGCYCPNGLIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGK 501

Query: 423  WSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD 482
            W C    CP  CSV G  HF+TFDG++YT    C Y+L K   S  FTV  +   CGL  
Sbjct: 502  WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQ 561

Query: 483  SETCLKSVTLSL-DGVQTVVVIKASGEVFLNQIYTQLPISAANV-TIFRPSTFFIIAQTS 540
               C++SV++ L    +  V +  +G+V L   Y  +P    +   I R S+ F+  +T+
Sbjct: 562  DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 621

Query: 541  LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600
            +G+++ L     ++L++Q+  +    T GLCG FN    DDF +  GV E+T   F N++
Sbjct: 622  VGVRV-LYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSW 680

Query: 601  KTQAAC-PNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMF 659
            KT +AC P +  S  DPC + ++   Y+   CS LT     F  C A + P  Y+  C  
Sbjct: 681  KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRR 738

Query: 660  DTCNCERSEDCLCAALSSYVHACAAKGVQLG-GWRDGVCTKPMTTCPKSMTYHYHVSTCQ 718
            D C C   + CLCA L+ Y H C   G+ +    R   C     +C  S  Y   V+ C 
Sbjct: 739  DACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACA---LSCEASKEYSPCVAPCG 793

Query: 719  PTCRSLSEGDITCSVGFIP-------VDGCICPKGTFLDDTGK-CVQASNCPCYHRGSMI 770
             TC+ L+  +  C V           V+GC CP  T+LD     CV  + C C+ +G   
Sbjct: 794  RTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 852

Query: 771  PNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPG---DTGAGCQKSC 827
            P G+S   S   C C  G +SC   +APA  C A  VF +C +            C++  
Sbjct: 853  PPGDSDIPSLGHCHCKDGVMSC-DSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQL 911

Query: 828  HTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTC 887
              L ++   P C+ GC CP GL+  G+  C   E+CPC      Y  G  +   C+TC C
Sbjct: 912  LNLSVSARGP-CLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVC 969

Query: 888  DSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVV 947
                ++CT  PC +TC  YGD HY TFDG  + F G C+  LV      K ++  SF V+
Sbjct: 970  QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVI 1023

Query: 948  TENVPCGTTGTTCSKAIKIFLGG----FELKLSHGKVEVIGTDESQEVPYTIRQMGIYLV 1003
             ENV C ++G  C K I I +G     F+    +   E    D+ QEV +T R     LV
Sbjct: 1024 VENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESF-LDDKQEV-HTWRVGFFTLV 1081

Query: 1004 VDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGN 1063
                  + LLWD++T++ +   P+++G++ GLCGNFD   +N+  T     + +  EFG+
Sbjct: 1082 HFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGS 1141

Query: 1064 SWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDA 1123
            SW  +  CPD L P+D C  NP R+ +A+K+CSIL    F  CH  V+   +Y  C+ D 
Sbjct: 1142 SWA-AVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1200

Query: 1124 CACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYN 1169
            C C  GGDCECFC +V+AYA  C + G+ V WRTP +CP  CD++N
Sbjct: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1246



 Score =  231 bits (590), Expect = 4e-60
 Identities = 152/486 (31%), Positives = 221/486 (45%), Gaps = 62/486 (12%)

Query: 821  AGCQKSCHTLDMTCYSPQ--CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTI 878
            A C  SCH    +C   +  CV GC CP+GL+ + +GGC+   +CPC  +   Y  G  +
Sbjct: 431  ACCPASCHPR-ASCVDSEIACVDGCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVV 488

Query: 879  RVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKD 938
            +  CNTCTC S  W C+   C A C+V GD H+ TFDG+ Y+F   C+Y L ++   G  
Sbjct: 489  KEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG-- 546

Query: 939  STQDSFRVVTENVPCGTTGT-TCSKAIKIFL------------GGFELKLSHGKVEVIGT 985
                +F V  +N PCG      C +++ + L             G  L     K+    T
Sbjct: 547  ----TFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYT 602

Query: 986  DESQEVPYTIRQMGIYLVVDTDIGLVLLWDKK-TSIFINLSPEFKGRVCGLCGNFDDIAV 1044
            D++ E+    R   ++L V T++G+ +L+D++   +++ +   +     GLCG F+    
Sbjct: 603  DDAFEIR---RLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQ 659

Query: 1045 NDFATRSRSVVGDVLEFGNSWKLSPSCPDALA--PKDPCTANPFRKSWAQKQCSILHGPT 1102
            +DF +           FGNSWK   +C   ++  P DPC  +    S++ + CS+L G  
Sbjct: 660  DDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM 719

Query: 1103 FAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTP-SIC 1161
            FA C A + P  Y+E C  DAC C       C C  +A YA  C   GL V +R     C
Sbjct: 720  FAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPAC 775

Query: 1162 PLFCDYYNPEGQCEWHYQPCGVPCLRTCRN---------PRGDCLRDVWGLEGCYPKCPP 1212
             L C+           Y PC  PC RTC++           GD L     +EGC   CPP
Sbjct: 776  ALSCE-------ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPP 826

Query: 1213 EAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPG-AVVPSDKNCQSCLCTERGVECTYK 1271
            +    D     CV     P     CH  G  Y PG + +PS  +C    C +  + C  +
Sbjct: 827  DT-YLDTQADLCV-----PRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSR 877

Query: 1272 AEACVC 1277
            A A  C
Sbjct: 878  APAAAC 883



 Score =  184 bits (468), Expect = 6e-46
 Identities = 136/449 (30%), Positives = 201/449 (44%), Gaps = 68/449 (15%)

Query: 887  CDSRMWRCTDDPCL----------ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGG 936
            CD R +  T   C           + C  +G  H  TFDG  Y  +G   YTLV  H   
Sbjct: 125  CDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRH--- 181

Query: 937  KDSTQDSFRVVTENVP-CGTTGTTCSKAIKIFLGGFE-----LKLSHGKVEVIGTDESQE 990
             +    SF +   N P CG++  TCS+A+ +F  G +      +++HG + V       +
Sbjct: 182  -EPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRV-------Q 233

Query: 991  VPYT-----IRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVN 1045
            +P+      ++Q+  Y++V       L WD  ++++I +SPE  G   GLCGN +    +
Sbjct: 234  LPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 293

Query: 1046 DFATRSRSVVGDVLEFGNSWKLS-----PSCPDALAPKDPCTA-NPFRKSWAQKQCSILH 1099
            D  T S  +  DV+EF +SW+       P    +  P+ PC   NP       +QC  L 
Sbjct: 294  DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL 353

Query: 1100 GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTP 1158
             P F ACHA+V P  +  +C +D C   S GD   +C A+A YA+AC + G  +  WRT 
Sbjct: 354  RPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 411

Query: 1159 -SICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCL-RDVWGLEGCYPKCPPEAPI 1216
               C + C       +  + Y  C   C  +C +PR  C+  ++  ++GCY  CP    I
Sbjct: 412  LRQCTVHCK------EKAFTYNECIACCPASC-HPRASCVDSEIACVDGCY--CP-NGLI 461

Query: 1217 FDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACV 1276
            F++      A CP       C  HG  Y PG+VV  D  C +C CT    EC+       
Sbjct: 462  FEDGGCVAPAECP-------CEFHGTLYPPGSVVKED--CNTCTCTSGKWECSTAVCPAE 512

Query: 1277 CTYNGQRFHPGDVIYHTTDGTGGCISARC 1305
            C+        GD+ + T DG      A C
Sbjct: 513  CSVT------GDIHFTTFDGRRYTFPATC 535



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 69/285 (24%), Positives = 110/285 (38%), Gaps = 18/285 (6%)

Query: 143  VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELDTK 202
            V I      V V+  PV  P S+ G  I+ +     +     + + W H   L++   +K
Sbjct: 2179 VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASK 2238

Query: 203  YAN-KTCGLCGDFNGMPVVSELLSHNTKL----TPMEFGNLQKMDDPTEQCQDPVPEPPR 257
             +  +  GLCG  +G       L   + +     P  F +  ++             P  
Sbjct: 2239 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298

Query: 258  NCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQ 317
              +T    C  ++  + FS C   V   S+ E       +  DT  +   C  L  Y   
Sbjct: 2299 CATTDCSPCLRMVSNRTFSACHRFVPPESFCEL------WIRDTKYVQQPCVALTVYVAM 2352

Query: 318  CTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD--TCSNQEHSRACEDHCVA---GC 372
            C H   +  +WR  D+CP  C ++  Y  C + C    TC +        +HC     GC
Sbjct: 2353 C-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2411

Query: 373  FCPEGTVLDDIGQTGCVPVSKCACVYN-GAAYAPGATYSTDCTNC 416
             C EGT+L       C+P +KCAC  + G   A G T+++  + C
Sbjct: 2412 VCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2456



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 79/334 (23%), Positives = 126/334 (37%), Gaps = 48/334 (14%)

Query: 875  GQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHC 934
            G  +RVG + C     +W C        C+++ D  ++TFDG   +   +  Y L Q+  
Sbjct: 2091 GLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSP- 2141

Query: 935  GGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGKVEVIGTDESQEV--- 991
              +  T       + N+        C   + +     ++ +     +V  T + Q V   
Sbjct: 2142 -DEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKV--TVDLQPVWPP 2198

Query: 992  ----PYTIRQMGIYLVVDTDIGLVLLWDKKTSIFI-NLSPEFKGRVCGLCGNFDDIAVND 1046
                 + I   G   ++ T   + + W   + + I   S   K +  GLCG  D  A ND
Sbjct: 2199 VSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAAND 2258

Query: 1047 FATRSRSVVG---DVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCS----ILH 1099
               +  SVVG   D   F +SW++    P +L         P   S A   CS    ++ 
Sbjct: 2259 LTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQTRFRP--DSCATTDCSPCLRMVS 2312

Query: 1100 GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPS 1159
              TF+ACH  V P  + E  + D             C A+  Y   CH+  +C+ WR   
Sbjct: 2313 NRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSD 2366

Query: 1160 ICPLFCDYYNPEGQCEWHYQPCGVPC--LRTCRN 1191
             CP  C         +  YQ C   C   +TC++
Sbjct: 2367 YCPFLC-------SSDSTYQACVTACEPPKTCQD 2393



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 148/661 (22%), Positives = 225/661 (34%), Gaps = 108/661 (16%)

Query: 386  TGCVPVSKCACV-----------YNGAAYAPGATYSTDCTNCTCS---GGRWSCQEVPCP 431
            T CVP+++  CV            N + + P       C     +   GG   C    C 
Sbjct: 2049 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECA 2108

Query: 432  GTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD---SETCLK 488
              CS+     F TFDG    +  +  Y+L++  D      + + +   L        CL 
Sbjct: 2109 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2168

Query: 489  SVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQ 548
             + ++    Q V + + + +V ++      P+S     I      ++I   S    + +Q
Sbjct: 2169 MLNMTHLAHQ-VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQ 2224

Query: 549  LVPTMQLFMQLAPKL-RGQTCGLCGNFNSIQADDFRTLSGVVEATA---AAFFNTFKTQA 604
             + +  L +  A K  + Q  GLCG  +   A+D     G V   A   A F ++++  +
Sbjct: 2225 WLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPS 2284

Query: 605  ACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNC 664
            +  ++  +   P S +  +        S  T     F  CH  V P ++    + DT   
Sbjct: 2285 SLTSVGQTRFRPDSCATTDCSPCLRMVSNRT-----FSACHRFVPPESFCELWIRDTKYV 2339

Query: 665  ERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQP--TCR 722
            ++     C AL+ YV  C    V +   R   C      C    TY   V+ C+P  TC+
Sbjct: 2340 QQP----CVALTVYVAMCHKFHVCIEWRRSDYCP---FLCSSDSTYQACVTACEPPKTCQ 2392

Query: 723  SLSEGDITCSVGFIPVDGCICPKGTFLD--DTGKCVQASNCPCY-HRGSMIPNGESVHDS 779
                G +      +  +GC+C +GT L    +  C+  + C C    G     GE+ + S
Sbjct: 2393 DGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSS 2452

Query: 780  GAICTCTHGKLSCIGGQAPAPV---CAAPM---------VFFDCRNATPGDTGAGC---Q 824
             + C C H    C       PV   C +P          V        P   G  C   Q
Sbjct: 2453 LSGC-CQH---QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQ 2508

Query: 825  KSCHTLDMTC------------------YSPQC---------VPGCVCPDGLVADGEG-G 856
              C  L  TC                  YS +C         VP C     L+    G  
Sbjct: 2509 TLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDS 2568

Query: 857  CITA-----EDCP-----CVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPC---LATC 903
            C T+      DCP     C   EA      T  + C    C    +RC    C    A  
Sbjct: 2569 CCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALV 2628

Query: 904  AVYGDGHYLTFDGQSYSFNGDCEYTLVQN-HCGGKDSTQDSFRVVTENVPCGTTGTTCSK 962
             V+       +     S   DC+   V   H   K    + F    ENV CG     C K
Sbjct: 2629 EVWSPDRCCPYK----SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENV-CGCAKYECVK 2683

Query: 963  A 963
            A
Sbjct: 2684 A 2684



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 104/450 (23%), Positives = 147/450 (32%), Gaps = 73/450 (16%)

Query: 1174 CEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCV--ATCPTP 1231
            CEW Y  C  PC +TCR+PR    RDV     C P C P   + DE   +CV    C  P
Sbjct: 1408 CEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVC-PTPQVLDEVTQRCVYLEDCVEP 1466

Query: 1232 PLPPRCHVHGKSYRP---GAVVPSDKNCQ------------------SCLCTERGVECTY 1270
             +       G    P   G   PSD+  Q                  + L T      T 
Sbjct: 1467 AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTA 1526

Query: 1271 KAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFS 1330
              E  V     Q      +    +    G   +      T      P +P +   P    
Sbjct: 1527 TEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQ 1586

Query: 1331 FSTPPLVVSSTHTP--------SNGPSSAHTGPPSSAWP------TTAG-------TSPR 1369
              TP +V  +  T         S   + +   PP+  +P      T  G       T+P 
Sbjct: 1587 TPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPP 1646

Query: 1370 TRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCES---PRS 1426
                TAS S  PV       SP      P   T SG    +  L     +V      P+ 
Sbjct: 1647 QPSLTASPSSRPVA------SPGAISRSP---TSSGSHKAV--LTPAVTKVISRTGVPQP 1695

Query: 1427 VECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLA--CSTS 1484
             + ++  +P  PL   G   +  P   L  R+ E             Q   P+    S  
Sbjct: 1696 TQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQ---PMGSPASPQ 1752

Query: 1485 SSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTA----RTTPAPGTATSVKKTFSTP 1540
              P  + PP  ++ T       + P  TP   SLSTA      TP     ++      + 
Sbjct: 1753 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1812

Query: 1541 SPP----PVPATSTSS-MSTTTPGTSVVSS 1565
             PP    P+    TS+ ++T  P  SV+++
Sbjct: 1813 LPPDTSLPLAKVGTSAPVATPGPKASVITT 1842



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 51/186 (27%), Positives = 71/186 (38%), Gaps = 33/186 (17%)

Query: 1848 PVTST--PVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYA------H 1899
            PVT+T  PV +P         PTQ+T       T + +    T +P +    A      H
Sbjct: 1523 PVTATEEPVVSPG--------PTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1574

Query: 1900 TTSTTSAPTARTTSAP--------TTRTT---SASPASTTSGPGNTPSPVPTTSTISAPT 1948
            T  ++S P A  T  P        TTR T   + SP  T S   + P+P     T +   
Sbjct: 1575 TPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSS-RSPPAPRFPLMTKAVTV 1633

Query: 1949 TSITSAPTTSTTSAP--TSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTT 2006
                S P  +T   P  T+S +S P  S  +   S T+S    +  +   T   S  G  
Sbjct: 1634 RGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV- 1692

Query: 2007 PSPVPT 2012
              P PT
Sbjct: 1693 --PQPT 1696



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 73/344 (21%), Positives = 117/344 (34%), Gaps = 47/344 (13%)

Query: 1687 VATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPT------ATSVTQGTHTTPVT 1740
            VA   PTP       +TT  T +  A +   T +SR  P         +VT   H +   
Sbjct: 1583 VALQTPTPGMVSGAMETTRVTVI-FAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPV 1641

Query: 1741 RNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRL---------- 1790
            R   P+ + T       PS  P         +   SG         +T++          
Sbjct: 1642 RTTPPQPSLTA-----SPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPT 1696

Query: 1791 QCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVT 1850
            Q ++ S P   +   G   +      L  R+       ++ L+ E        P G P +
Sbjct: 1697 QAQSASSPSTPLTVAGTAAEQVPVSPLATRS------LEIVLSTEKGEAGHSQPMGSPAS 1750

Query: 1851 STPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTAR 1910
              P   PS P              + ++ TT+ T S    P+T    + +T+T       
Sbjct: 1751 PQPHPLPSAPP-------------RPAQHTTMATRSPALPPETPAAASLSTATDGLAATP 1797

Query: 1911 TTSAPTTRTTSASPASTTSG-PGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTS 1969
              S  +TR     P+   SG P +T  P+    T +   T    A   +T   P ++T  
Sbjct: 1798 FMSLESTR-----PSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLP 1852

Query: 1970 APTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
            A T S     T +  +     T  AP  + T+      + +PT+
Sbjct: 1853 AQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTS 1896



 Score = 39.3 bits (90), Expect = 0.039
 Identities = 47/167 (28%), Positives = 64/167 (38%), Gaps = 21/167 (12%)

Query: 1850 TSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTA 1909
            TS PV  P   +    +P Q  ++   ++T + V   T +    + T AH  +  + P A
Sbjct: 1826 TSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPA----AMTQAHPPTHIAPPAA 1881

Query: 1910 RTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTS--APTSST 1967
             T  AP     +  P S     G  P    T S +S         P  STT   A  S  
Sbjct: 1882 GT--APGLLLGATLPTS-----GVLPVAEGTASMVSV-------VPRKSTTGKVAILSKQ 1927

Query: 1968 TSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSG-PGTTPSPVPTT 2013
             S PT+   SA    T  +P TS    P  +   G    T  PVPT+
Sbjct: 1928 VSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTS 1974



 Score = 35.8 bits (81), Expect = 0.44
 Identities = 40/185 (21%), Positives = 60/185 (32%), Gaps = 35/185 (18%)

Query: 1855 TAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST-----TSAPTA 1909
            T P +      S  +   S +  RT T     T + P T+      T+T     +  PT 
Sbjct: 1479 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQ 1538

Query: 1910 RTTSAPTTRTTSASPASTTSGPG------------NTPSPVPTTSTISAPTTSITSAPTT 1957
             T   P   T S  PA  T  P             +TP        +  PT  + S    
Sbjct: 1539 TTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAME 1598

Query: 1958 STTSAPTSSTTSAPTTSTTSAPTSS------------------TTSSPQTSTTSAPTTST 1999
            +T      + +   T S+ S P                      T+ PQ S T++P++  
Sbjct: 1599 TTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRP 1658

Query: 2000 TSGPG 2004
             + PG
Sbjct: 1659 VASPG 1663



 Score = 35.8 bits (81), Expect = 0.44
 Identities = 33/129 (25%), Positives = 42/129 (32%), Gaps = 16/129 (12%)

Query: 1885 TSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTI 1944
            T +   PQ S     T      PT R    P    T+A     T+      SP PT +T+
Sbjct: 1488 TPSDEEPQLSQESPRT------PTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTL 1541

Query: 1945 SAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPG 2004
              P     S      T +P S   +A   +    P SS          S P    T  PG
Sbjct: 1542 QQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESS----------SLPVALQTPTPG 1591

Query: 2005 TTPSPVPTT 2013
                 + TT
Sbjct: 1592 MVSGAMETT 1600



 Score = 32.7 bits (73), Expect = 3.7
 Identities = 31/104 (29%), Positives = 45/104 (43%), Gaps = 16/104 (15%)

Query: 1477 TPLACSTSSSPAQTT---PPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSV 1533
            TP     S+ P+Q     PP TS        G+SAP +TPG  +  +  TTP    AT++
Sbjct: 1796 TPFMSLESTRPSQLLSGLPPDTS--LPLAKVGTSAPVATPGPKA--SVITTPLQPQATTL 1851

Query: 1534 KKTFSTPSPPPVPATSTSS---------MSTTTPGTSVVSSKPT 1568
                 +P  P  PA  T +          + T PG  + ++ PT
Sbjct: 1852 PAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPT 1895



 Score = 31.6 bits (70), Expect = 8.2
 Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 13/68 (19%)

Query: 327  DWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQT 386
            +WR  D C   C     +  CR P A +C +    R+C         CP   VLD++ Q 
Sbjct: 1409 EWRY-DACASPC-----FQTCRDPRAASCRDVPRGRSCVP------VCPTPQVLDEVTQR 1456

Query: 387  GCVPVSKC 394
             CV +  C
Sbjct: 1457 -CVYLEDC 1463



 Score = 31.6 bits (70), Expect = 8.2
 Identities = 46/182 (25%), Positives = 60/182 (32%), Gaps = 34/182 (18%)

Query: 1848 PVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAP 1907
            P T     A  T  G  +  T  TS        T    S      T+   A  +   S P
Sbjct: 1872 PPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLP 1931

Query: 1908 TARTTSA---PTTRTTSASP------ASTTSGPGNTPSPVPTTSTIS------APTTSI- 1951
            T+   SA   PT  T + S       A        T  PVPT+  +S      AP  S+ 
Sbjct: 1932 TSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSML 1991

Query: 1952 -----------TSA-------PTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTS 1993
                       TSA       P    T+ P+  +  A +     A   +TT+   TSTT 
Sbjct: 1992 VLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTC 2051

Query: 1994 AP 1995
             P
Sbjct: 2052 VP 2053


>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score =  612 bits (1577), Expect = e-174
 Identities = 381/1126 (33%), Positives = 548/1126 (48%), Gaps = 65/1126 (5%)

Query: 80   VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQE--SAAPTLSRV- 136
            +C  WG  H +TFDG  +   G  +Y          + F+IQ+    +  S+  T SR  
Sbjct: 78   ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137

Query: 137  -LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSL 195
             L  V    I L K  V   G  V LP       +QQ + Y  V  +    L W+   ++
Sbjct: 138  SLFFVGEQEIHLAK-EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAV 196

Query: 196  LLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL---QKMDDPTEQCQD 250
             +++  +    T GLCG+ N  P   +L++ + KLT   +EF +    Q  + P      
Sbjct: 197  YIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255

Query: 251  PVPEPP---RNCSTGFGI---CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304
             +P PP   +N  T  G+   CE LL    F  C A V    +  +C  DLC  +    +
Sbjct: 256  SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLC--QSMGDV 312

Query: 305  SCVCHTLAEYSRQCTHAGGLPQDWRGP-DFCPQKCPNN-MQYHECRSPCADTCSNQEHSR 362
            +  C  LAEY+R C  AG   Q WR     C   C      Y+EC + C  +C  +    
Sbjct: 313  ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCV 372

Query: 363  ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGR 422
              E  CV GC+CP G + +D    GCV  ++C C ++G  Y PG+    DC  CTC+ G+
Sbjct: 373  DSEIACVDGCYCPNGLIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGK 429

Query: 423  WSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD 482
            W C    CP  CSV G  HF+TFDG++YT    C Y+L K   S  FTV  +   CGL  
Sbjct: 430  WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQ 489

Query: 483  SETCLKSVTLSL-DGVQTVVVIKASGEVFLNQIYTQLPISAANV-TIFRPSTFFIIAQTS 540
               C++SV++ L    +  V +  +G+V L   Y  +P    +   I R S+ F+  +T+
Sbjct: 490  DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 549

Query: 541  LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600
            +G+++ L     ++L++Q+  +    T GLCG FN    DDF +  GV E+T   F N++
Sbjct: 550  VGVRV-LYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSW 608

Query: 601  KTQAAC-PNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMF 659
            KT +AC P +  S  DPC + ++   Y+   CS LT     F  C A + P  Y+  C  
Sbjct: 609  KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRR 666

Query: 660  DTCNCERSEDCLCAALSSYVHACAAKGVQLG-GWRDGVCTKPMTTCPKSMTYHYHVSTCQ 718
            D C C   + CLCA L+ Y H C   G+ +    R   C     +C  S  Y   V+ C 
Sbjct: 667  DACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACA---LSCEASKEYSPCVAPCG 721

Query: 719  PTCRSLSEGDITCSVGFIP-------VDGCICPKGTFLDDTGK-CVQASNCPCYHRGSMI 770
             TC+ L+  +  C V           V+GC CP  T+LD     CV  + C C+ +G   
Sbjct: 722  RTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780

Query: 771  PNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPG---DTGAGCQKSC 827
            P G+S   S   C C  G +SC   +APA  C A  VF +C +            C++  
Sbjct: 781  PPGDSDIPSLGHCHCKDGVMSC-DSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQL 839

Query: 828  HTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTC 887
              L ++   P C+ GC CP GL+  G+  C   E+CPC      Y  G  +   C+TC C
Sbjct: 840  LNLSVSARGP-CLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVC 897

Query: 888  DSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVV 947
                ++CT  PC +TC  YGD HY TFDG  + F G C+  LV      K ++  SF V+
Sbjct: 898  QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVI 951

Query: 948  TENVPCGTTGTTCSKAIKIFLGG----FELKLSHGKVEVIGTDESQEVPYTIRQMGIYLV 1003
             ENV C ++G  C K I I +G     F+    +   E    D+ QEV +T R     LV
Sbjct: 952  VENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESF-LDDKQEV-HTWRVGFFTLV 1009

Query: 1004 VDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGN 1063
                  + LLWD++T++ +   P+++G++ GLCGNFD   +N+  T     + +  EFG+
Sbjct: 1010 HFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGS 1069

Query: 1064 SWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDA 1123
            SW  +  CPD L P+D C  NP R+ +A+K+CSIL    F  CH  V+   +Y  C+ D 
Sbjct: 1070 SWA-AVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1128

Query: 1124 CACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYN 1169
            C C  GGDCECFC +V+AYA  C + G+ V WRTP +CP  CD++N
Sbjct: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174



 Score =  231 bits (590), Expect = 4e-60
 Identities = 152/486 (31%), Positives = 221/486 (45%), Gaps = 62/486 (12%)

Query: 821  AGCQKSCHTLDMTCYSPQ--CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTI 878
            A C  SCH    +C   +  CV GC CP+GL+ + +GGC+   +CPC  +   Y  G  +
Sbjct: 359  ACCPASCHPR-ASCVDSEIACVDGCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVV 416

Query: 879  RVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKD 938
            +  CNTCTC S  W C+   C A C+V GD H+ TFDG+ Y+F   C+Y L ++   G  
Sbjct: 417  KEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG-- 474

Query: 939  STQDSFRVVTENVPCGTTGT-TCSKAIKIFL------------GGFELKLSHGKVEVIGT 985
                +F V  +N PCG      C +++ + L             G  L     K+    T
Sbjct: 475  ----TFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYT 530

Query: 986  DESQEVPYTIRQMGIYLVVDTDIGLVLLWDKK-TSIFINLSPEFKGRVCGLCGNFDDIAV 1044
            D++ E+    R   ++L V T++G+ +L+D++   +++ +   +     GLCG F+    
Sbjct: 531  DDAFEIR---RLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQ 587

Query: 1045 NDFATRSRSVVGDVLEFGNSWKLSPSCPDALA--PKDPCTANPFRKSWAQKQCSILHGPT 1102
            +DF +           FGNSWK   +C   ++  P DPC  +    S++ + CS+L G  
Sbjct: 588  DDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM 647

Query: 1103 FAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTP-SIC 1161
            FA C A + P  Y+E C  DAC C       C C  +A YA  C   GL V +R     C
Sbjct: 648  FAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPAC 703

Query: 1162 PLFCDYYNPEGQCEWHYQPCGVPCLRTCRN---------PRGDCLRDVWGLEGCYPKCPP 1212
             L C+           Y PC  PC RTC++           GD L     +EGC   CPP
Sbjct: 704  ALSCE-------ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPP 754

Query: 1213 EAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPG-AVVPSDKNCQSCLCTERGVECTYK 1271
            +    D     CV     P     CH  G  Y PG + +PS  +C    C +  + C  +
Sbjct: 755  DT-YLDTQADLCV-----PRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSR 805

Query: 1272 AEACVC 1277
            A A  C
Sbjct: 806  APAAAC 811



 Score =  184 bits (468), Expect = 6e-46
 Identities = 136/449 (30%), Positives = 201/449 (44%), Gaps = 68/449 (15%)

Query: 887  CDSRMWRCTDDPCL----------ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGG 936
            CD R +  T   C           + C  +G  H  TFDG  Y  +G   YTLV  H   
Sbjct: 53   CDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRH--- 109

Query: 937  KDSTQDSFRVVTENVP-CGTTGTTCSKAIKIFLGGFE-----LKLSHGKVEVIGTDESQE 990
             +    SF +   N P CG++  TCS+A+ +F  G +      +++HG + V       +
Sbjct: 110  -EPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRV-------Q 161

Query: 991  VPYT-----IRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVN 1045
            +P+      ++Q+  Y++V       L WD  ++++I +SPE  G   GLCGN +    +
Sbjct: 162  LPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221

Query: 1046 DFATRSRSVVGDVLEFGNSWKLS-----PSCPDALAPKDPCTA-NPFRKSWAQKQCSILH 1099
            D  T S  +  DV+EF +SW+       P    +  P+ PC   NP       +QC  L 
Sbjct: 222  DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL 281

Query: 1100 GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTP 1158
             P F ACHA+V P  +  +C +D C   S GD   +C A+A YA+AC + G  +  WRT 
Sbjct: 282  RPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 339

Query: 1159 -SICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCL-RDVWGLEGCYPKCPPEAPI 1216
               C + C       +  + Y  C   C  +C +PR  C+  ++  ++GCY  CP    I
Sbjct: 340  LRQCTVHCK------EKAFTYNECIACCPASC-HPRASCVDSEIACVDGCY--CP-NGLI 389

Query: 1217 FDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACV 1276
            F++      A CP       C  HG  Y PG+VV  D  C +C CT    EC+       
Sbjct: 390  FEDGGCVAPAECP-------CEFHGTLYPPGSVVKED--CNTCTCTSGKWECSTAVCPAE 440

Query: 1277 CTYNGQRFHPGDVIYHTTDGTGGCISARC 1305
            C+        GD+ + T DG      A C
Sbjct: 441  CSVT------GDIHFTTFDGRRYTFPATC 463



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 69/285 (24%), Positives = 110/285 (38%), Gaps = 18/285 (6%)

Query: 143  VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELDTK 202
            V I      V V+  PV  P S+ G  I+ +     +     + + W H   L++   +K
Sbjct: 2107 VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASK 2166

Query: 203  YAN-KTCGLCGDFNGMPVVSELLSHNTKL----TPMEFGNLQKMDDPTEQCQDPVPEPPR 257
             +  +  GLCG  +G       L   + +     P  F +  ++             P  
Sbjct: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226

Query: 258  NCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQ 317
              +T    C  ++  + FS C   V   S+ E       +  DT  +   C  L  Y   
Sbjct: 2227 CATTDCSPCLRMVSNRTFSACHRFVPPESFCEL------WIRDTKYVQQPCVALTVYVAM 2280

Query: 318  CTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD--TCSNQEHSRACEDHCVA---GC 372
            C H   +  +WR  D+CP  C ++  Y  C + C    TC +        +HC     GC
Sbjct: 2281 C-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2339

Query: 373  FCPEGTVLDDIGQTGCVPVSKCACVYN-GAAYAPGATYSTDCTNC 416
             C EGT+L       C+P +KCAC  + G   A G T+++  + C
Sbjct: 2340 VCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2384



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 79/334 (23%), Positives = 126/334 (37%), Gaps = 48/334 (14%)

Query: 875  GQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHC 934
            G  +RVG + C     +W C        C+++ D  ++TFDG   +   +  Y L Q+  
Sbjct: 2019 GLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSP- 2069

Query: 935  GGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGKVEVIGTDESQEV--- 991
              +  T       + N+        C   + +     ++ +     +V  T + Q V   
Sbjct: 2070 -DEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKV--TVDLQPVWPP 2126

Query: 992  ----PYTIRQMGIYLVVDTDIGLVLLWDKKTSIFI-NLSPEFKGRVCGLCGNFDDIAVND 1046
                 + I   G   ++ T   + + W   + + I   S   K +  GLCG  D  A ND
Sbjct: 2127 VSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAAND 2186

Query: 1047 FATRSRSVVG---DVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCS----ILH 1099
               +  SVVG   D   F +SW++    P +L         P   S A   CS    ++ 
Sbjct: 2187 LTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQTRFRP--DSCATTDCSPCLRMVS 2240

Query: 1100 GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPS 1159
              TF+ACH  V P  + E  + D             C A+  Y   CH+  +C+ WR   
Sbjct: 2241 NRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSD 2294

Query: 1160 ICPLFCDYYNPEGQCEWHYQPCGVPC--LRTCRN 1191
             CP  C         +  YQ C   C   +TC++
Sbjct: 2295 YCPFLC-------SSDSTYQACVTACEPPKTCQD 2321



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 148/661 (22%), Positives = 225/661 (34%), Gaps = 108/661 (16%)

Query: 386  TGCVPVSKCACV-----------YNGAAYAPGATYSTDCTNCTCS---GGRWSCQEVPCP 431
            T CVP+++  CV            N + + P       C     +   GG   C    C 
Sbjct: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECA 2036

Query: 432  GTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD---SETCLK 488
              CS+     F TFDG    +  +  Y+L++  D      + + +   L        CL 
Sbjct: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096

Query: 489  SVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQ 548
             + ++    Q V + + + +V ++      P+S     I      ++I   S    + +Q
Sbjct: 2097 MLNMTHLAHQ-VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQ 2152

Query: 549  LVPTMQLFMQLAPKL-RGQTCGLCGNFNSIQADDFRTLSGVVEATA---AAFFNTFKTQA 604
             + +  L +  A K  + Q  GLCG  +   A+D     G V   A   A F ++++  +
Sbjct: 2153 WLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPS 2212

Query: 605  ACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNC 664
            +  ++  +   P S +  +        S  T     F  CH  V P ++    + DT   
Sbjct: 2213 SLTSVGQTRFRPDSCATTDCSPCLRMVSNRT-----FSACHRFVPPESFCELWIRDTKYV 2267

Query: 665  ERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQP--TCR 722
            ++     C AL+ YV  C    V +   R   C      C    TY   V+ C+P  TC+
Sbjct: 2268 QQP----CVALTVYVAMCHKFHVCIEWRRSDYCP---FLCSSDSTYQACVTACEPPKTCQ 2320

Query: 723  SLSEGDITCSVGFIPVDGCICPKGTFLD--DTGKCVQASNCPCY-HRGSMIPNGESVHDS 779
                G +      +  +GC+C +GT L    +  C+  + C C    G     GE+ + S
Sbjct: 2321 DGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSS 2380

Query: 780  GAICTCTHGKLSCIGGQAPAPV---CAAPM---------VFFDCRNATPGDTGAGC---Q 824
             + C C H    C       PV   C +P          V        P   G  C   Q
Sbjct: 2381 LSGC-CQH---QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQ 2436

Query: 825  KSCHTLDMTC------------------YSPQC---------VPGCVCPDGLVADGEG-G 856
              C  L  TC                  YS +C         VP C     L+    G  
Sbjct: 2437 TLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDS 2496

Query: 857  CITA-----EDCP-----CVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPC---LATC 903
            C T+      DCP     C   EA      T  + C    C    +RC    C    A  
Sbjct: 2497 CCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALV 2556

Query: 904  AVYGDGHYLTFDGQSYSFNGDCEYTLVQN-HCGGKDSTQDSFRVVTENVPCGTTGTTCSK 962
             V+       +     S   DC+   V   H   K    + F    ENV CG     C K
Sbjct: 2557 EVWSPDRCCPYK----SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENV-CGCAKYECVK 2611

Query: 963  A 963
            A
Sbjct: 2612 A 2612



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 106/450 (23%), Positives = 150/450 (33%), Gaps = 73/450 (16%)

Query: 1174 CEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCV--ATCPTP 1231
            CEW Y  C  PC +TCR+PR    RDV  +EGC P C P   + DE   +CV    C  P
Sbjct: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVC-PTPQVLDEVTQRCVYLEDCVEP 1394

Query: 1232 PLPPRCHVHGKSYRP---GAVVPSDKNCQ------------------SCLCTERGVECTY 1270
             +       G    P   G   PSD+  Q                  + L T      T 
Sbjct: 1395 AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTA 1454

Query: 1271 KAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFS 1330
              E  V     Q      +    +    G   +      T      P +P +   P    
Sbjct: 1455 TEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQ 1514

Query: 1331 FSTPPLVVSSTHTP--------SNGPSSAHTGPPSSAWP------TTAG-------TSPR 1369
              TP +V  +  T         S   + +   PP+  +P      T  G       T+P 
Sbjct: 1515 TPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPL 1574

Query: 1370 TRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCES---PRS 1426
                TAS S  PV       SP      P   T SG    +  L     +V      P+ 
Sbjct: 1575 QPSLTASPSSRPVA------SPGAISRSP---TSSGSHKAV--LTPAVTKVISRTGVPQP 1623

Query: 1427 VECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLA--CSTS 1484
             + ++  +P  PL   G   +  P   L  R+ E             Q   P+    S  
Sbjct: 1624 TQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQ---PMGSPASPQ 1680

Query: 1485 SSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTA----RTTPAPGTATSVKKTFSTP 1540
              P  + PP  ++ T       + P  TP   SLSTA      TP     ++      + 
Sbjct: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740

Query: 1541 SPP----PVPATSTSS-MSTTTPGTSVVSS 1565
             PP    P+    TS+ ++T  P  SV+++
Sbjct: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITT 1770



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 51/186 (27%), Positives = 71/186 (38%), Gaps = 33/186 (17%)

Query: 1848 PVTST--PVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYA------H 1899
            PVT+T  PV +P         PTQ+T       T + +    T +P +    A      H
Sbjct: 1451 PVTATEEPVVSPG--------PTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1502

Query: 1900 TTSTTSAPTARTTSAP--------TTRTT---SASPASTTSGPGNTPSPVPTTSTISAPT 1948
            T  ++S P A  T  P        TTR T   + SP  T S   + P+P     T +   
Sbjct: 1503 TPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSS-RSPPAPRFPLMTKAVTV 1561

Query: 1949 TSITSAPTTSTTSAP--TSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTT 2006
                S P  +T   P  T+S +S P  S  +   S T+S    +  +   T   S  G  
Sbjct: 1562 RGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV- 1620

Query: 2007 PSPVPT 2012
              P PT
Sbjct: 1621 --PQPT 1624



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 55/200 (27%), Positives = 78/200 (39%), Gaps = 25/200 (12%)

Query: 1826 GPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTT 1885
            GP +  L   + +   + P G   T +P +   T S  AI  T  +SS        L   
Sbjct: 1463 GPTQTTLQQPLELTASQLPAG--PTESPASKGVTASLLAIPHTPESSS--------LPVA 1512

Query: 1886 STTSTPQTSTTYAHTTSTT----SAP--TARTTSAPTTRTTSASPASTTSGPGNTPSPVP 1939
              T TP   +    TT  T     +P  T  + S P  R    + A T  G G+ P  V 
Sbjct: 1513 LQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLP--VR 1570

Query: 1940 TTSTISAPTTSITSAPTTST---TSAPTSSTTSAPTTSTTSAPTSSTTSSPQTS---TTS 1993
            TT    + T S +S P  S    + +PTSS +     +       S T  PQ +   + S
Sbjct: 1571 TTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSAS 1630

Query: 1994 APTTSTTSGPGTTPSPVPTT 2013
            +P+T  T   GT    VP +
Sbjct: 1631 SPSTPLTVA-GTAAEQVPVS 1649



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 51/195 (26%), Positives = 72/195 (36%), Gaps = 31/195 (15%)

Query: 1843 TPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTS 1902
            TP    +T++P + P    G AIS + ++S   K+  T  VT   + T     T A + S
Sbjct: 1572 TPLQPSLTASPSSRPVASPG-AISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSAS 1630

Query: 1903 TTSAPTARTTSAPTTRTTSASPASTTS------------------GPGNTPSPVPTTSTI 1944
            + S P   T +         SP +T S                  G   +P P P  S  
Sbjct: 1631 SPSTPL--TVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAP 1688

Query: 1945 SAP---TTSITSAPTTST-TSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTST- 1999
              P   TT  T +P     T A  S +T+    + T   +  +T   Q  +   P TS  
Sbjct: 1689 PRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLP 1748

Query: 2000 -----TSGPGTTPSP 2009
                 TS P  TP P
Sbjct: 1749 LAKVGTSAPVATPGP 1763



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 81/357 (22%), Positives = 121/357 (33%), Gaps = 49/357 (13%)

Query: 1684 PKTVATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNC 1743
            P   AT  P   P    TQTT    +   +++ P      GPT +  ++G  T  +    
Sbjct: 1450 PPVTATEEPVVSP--GPTQTTLQQPLELTASQLPA-----GPTESPASKGV-TASLLAIP 1501

Query: 1744 HPRCTWTKWFDVDFPSPGPHGGDKETYN-NIIRSGEK---ICRRPEEITRLQCRAKS--- 1796
            H   + +    +  P+PG   G  ET    +I +G     +  R     R     K+   
Sbjct: 1502 HTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTV 1561

Query: 1797 -------------HPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCET 1843
                          P ++     + V      G + R+    G  K  L   V  +   T
Sbjct: 1562 RGHGSLPVRTTPLQPSLTASPSSRPVA---SPGAISRSPTSSGSHKAVLTPAVTKVISRT 1618

Query: 1844 PRGCPVTSTPVTAPSTPSGRA-ISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTS 1902
                P  +   ++PSTP   A  +  Q   S   +R+  +V ++       S       S
Sbjct: 1619 GVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPAS 1678

Query: 1903 TTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSA 1962
                P       P   TT A     T  P   P   P  +++S  T  + + P  S  S 
Sbjct: 1679 PQPHPLPSAPPRPAQHTTMA-----TRSPA-LPPETPAAASLSTATDGLAATPFMSLEST 1732

Query: 1963 PTSSTTSA--PTTST------TSAPTSSTTSSPQTSTTSAP-TTSTTSGPGTTPSPV 2010
              S   S   P TS       TSAP +  T  P+ S  + P     T+ P  T SPV
Sbjct: 1733 RPSQLLSGLPPDTSLPLAKVGTSAPVA--TPGPKASVITTPLQPQATTLPAQTLSPV 1787



 Score = 40.8 bits (94), Expect = 0.014
 Identities = 40/171 (23%), Positives = 64/171 (37%), Gaps = 19/171 (11%)

Query: 1844 PRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST 1903
            P G P +  P   PS P              + ++ TT+ T S    P+T    + +T+T
Sbjct: 1672 PMGSPASPQPHPLPSAPP-------------RPAQHTTMATRSPALPPETPAAASLSTAT 1718

Query: 1904 TSAPTARTTSAPTTRTTSASPASTTSG-PGNTPSPVPTTSTISAPTTSITSAPTTSTTSA 1962
                     S  +TR     P+   SG P +T  P+    T +   T    A   +T   
Sbjct: 1719 DGLAATPFMSLESTR-----PSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQ 1773

Query: 1963 PTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
            P ++T  A T S     T +  +     T  AP  + T+      + +PT+
Sbjct: 1774 PQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTS 1824



 Score = 39.3 bits (90), Expect = 0.039
 Identities = 47/167 (28%), Positives = 64/167 (38%), Gaps = 21/167 (12%)

Query: 1850 TSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTA 1909
            TS PV  P   +    +P Q  ++   ++T + V   T +    + T AH  +  + P A
Sbjct: 1754 TSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPA----AMTQAHPPTHIAPPAA 1809

Query: 1910 RTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTS--APTSST 1967
             T  AP     +  P S     G  P    T S +S         P  STT   A  S  
Sbjct: 1810 GT--APGLLLGATLPTS-----GVLPVAEGTASMVSV-------VPRKSTTGKVAILSKQ 1855

Query: 1968 TSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSG-PGTTPSPVPTT 2013
             S PT+   SA    T  +P TS    P  +   G    T  PVPT+
Sbjct: 1856 VSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTS 1902



 Score = 35.8 bits (81), Expect = 0.44
 Identities = 43/169 (25%), Positives = 59/169 (34%), Gaps = 13/169 (7%)

Query: 1855 TAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST-----TSAPTA 1909
            T P +      S  +   S +  RT T     T + P T+      T+T     +  PT 
Sbjct: 1407 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQ 1466

Query: 1910 RTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAP-TTSITSAPTTSTTSAPTSSTT 1968
             T   P   T S  PA  T  P    S   T S ++ P T   +S P    T  P   + 
Sbjct: 1467 TTLQQPLELTASQLPAGPTESPA---SKGVTASLLAIPHTPESSSLPVALQTPTPGMVSG 1523

Query: 1969 SAPTTSTTSAPTSSTTSSPQTSTTSAP----TTSTTSGPGTTPSPVPTT 2013
            +  TT  T     S   +  + +  AP     T   +  G    PV TT
Sbjct: 1524 AMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1572



 Score = 34.7 bits (78), Expect = 0.97
 Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 3/54 (5%)

Query: 343  QYHECRSPCADTCSNQEHSRACEDHCVAGC--FCPEGTVLDDIGQTGCVPVSKC 394
            +Y  C SPC  TC +   +   +   V GC   CP   VLD++ Q  CV +  C
Sbjct: 1339 RYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQR-CVYLEDC 1391



 Score = 32.7 bits (73), Expect = 3.7
 Identities = 31/104 (29%), Positives = 45/104 (43%), Gaps = 16/104 (15%)

Query: 1477 TPLACSTSSSPAQTT---PPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSV 1533
            TP     S+ P+Q     PP TS        G+SAP +TPG  +  +  TTP    AT++
Sbjct: 1724 TPFMSLESTRPSQLLSGLPPDTS--LPLAKVGTSAPVATPGPKA--SVITTPLQPQATTL 1779

Query: 1534 KKTFSTPSPPPVPATSTSS---------MSTTTPGTSVVSSKPT 1568
                 +P  P  PA  T +          + T PG  + ++ PT
Sbjct: 1780 PAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPT 1823



 Score = 31.6 bits (70), Expect = 8.2
 Identities = 46/182 (25%), Positives = 60/182 (32%), Gaps = 34/182 (18%)

Query: 1848 PVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAP 1907
            P T     A  T  G  +  T  TS        T    S      T+   A  +   S P
Sbjct: 1800 PPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLP 1859

Query: 1908 TARTTSA---PTTRTTSASP------ASTTSGPGNTPSPVPTTSTIS------APTTSI- 1951
            T+   SA   PT  T + S       A        T  PVPT+  +S      AP  S+ 
Sbjct: 1860 TSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSML 1919

Query: 1952 -----------TSA-------PTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTS 1993
                       TSA       P    T+ P+  +  A +     A   +TT+   TSTT 
Sbjct: 1920 VLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTC 1979

Query: 1994 AP 1995
             P
Sbjct: 1980 VP 1981


>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score =  612 bits (1577), Expect = e-174
 Identities = 381/1126 (33%), Positives = 548/1126 (48%), Gaps = 65/1126 (5%)

Query: 80   VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQE--SAAPTLSRV- 136
            +C  WG  H +TFDG  +   G  +Y          + F+IQ+    +  S+  T SR  
Sbjct: 150  ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 209

Query: 137  -LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSL 195
             L  V    I L K  V   G  V LP       +QQ + Y  V  +    L W+   ++
Sbjct: 210  SLFFVGEQEIHLAK-EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAV 268

Query: 196  LLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL---QKMDDPTEQCQD 250
             +++  +    T GLCG+ N  P   +L++ + KLT   +EF +    Q  + P      
Sbjct: 269  YIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327

Query: 251  PVPEPP---RNCSTGFGI---CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304
             +P PP   +N  T  G+   CE LL    F  C A V    +  +C  DLC  +    +
Sbjct: 328  SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLC--QSMGDV 384

Query: 305  SCVCHTLAEYSRQCTHAGGLPQDWRGP-DFCPQKCPNN-MQYHECRSPCADTCSNQEHSR 362
            +  C  LAEY+R C  AG   Q WR     C   C      Y+EC + C  +C  +    
Sbjct: 385  ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCV 444

Query: 363  ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGR 422
              E  CV GC+CP G + +D    GCV  ++C C ++G  Y PG+    DC  CTC+ G+
Sbjct: 445  DSEIACVDGCYCPNGLIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGK 501

Query: 423  WSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD 482
            W C    CP  CSV G  HF+TFDG++YT    C Y+L K   S  FTV  +   CGL  
Sbjct: 502  WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQ 561

Query: 483  SETCLKSVTLSL-DGVQTVVVIKASGEVFLNQIYTQLPISAANV-TIFRPSTFFIIAQTS 540
               C++SV++ L    +  V +  +G+V L   Y  +P    +   I R S+ F+  +T+
Sbjct: 562  DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 621

Query: 541  LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600
            +G+++ L     ++L++Q+  +    T GLCG FN    DDF +  GV E+T   F N++
Sbjct: 622  VGVRV-LYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSW 680

Query: 601  KTQAAC-PNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMF 659
            KT +AC P +  S  DPC + ++   Y+   CS LT     F  C A + P  Y+  C  
Sbjct: 681  KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRR 738

Query: 660  DTCNCERSEDCLCAALSSYVHACAAKGVQLG-GWRDGVCTKPMTTCPKSMTYHYHVSTCQ 718
            D C C   + CLCA L+ Y H C   G+ +    R   C     +C  S  Y   V+ C 
Sbjct: 739  DACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACA---LSCEASKEYSPCVAPCG 793

Query: 719  PTCRSLSEGDITCSVGFIP-------VDGCICPKGTFLDDTGK-CVQASNCPCYHRGSMI 770
             TC+ L+  +  C V           V+GC CP  T+LD     CV  + C C+ +G   
Sbjct: 794  RTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 852

Query: 771  PNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPG---DTGAGCQKSC 827
            P G+S   S   C C  G +SC   +APA  C A  VF +C +            C++  
Sbjct: 853  PPGDSDIPSLGHCHCKDGVMSC-DSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQL 911

Query: 828  HTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTC 887
              L ++   P C+ GC CP GL+  G+  C   E+CPC      Y  G  +   C+TC C
Sbjct: 912  LNLSVSARGP-CLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVC 969

Query: 888  DSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVV 947
                ++CT  PC +TC  YGD HY TFDG  + F G C+  LV      K ++  SF V+
Sbjct: 970  QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVI 1023

Query: 948  TENVPCGTTGTTCSKAIKIFLGG----FELKLSHGKVEVIGTDESQEVPYTIRQMGIYLV 1003
             ENV C ++G  C K I I +G     F+    +   E    D+ QEV +T R     LV
Sbjct: 1024 VENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESF-LDDKQEV-HTWRVGFFTLV 1081

Query: 1004 VDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGN 1063
                  + LLWD++T++ +   P+++G++ GLCGNFD   +N+  T     + +  EFG+
Sbjct: 1082 HFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGS 1141

Query: 1064 SWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDA 1123
            SW  +  CPD L P+D C  NP R+ +A+K+CSIL    F  CH  V+   +Y  C+ D 
Sbjct: 1142 SWA-AVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1200

Query: 1124 CACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYN 1169
            C C  GGDCECFC +V+AYA  C + G+ V WRTP +CP  CD++N
Sbjct: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1246



 Score =  231 bits (590), Expect = 4e-60
 Identities = 152/486 (31%), Positives = 221/486 (45%), Gaps = 62/486 (12%)

Query: 821  AGCQKSCHTLDMTCYSPQ--CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTI 878
            A C  SCH    +C   +  CV GC CP+GL+ + +GGC+   +CPC  +   Y  G  +
Sbjct: 431  ACCPASCHPR-ASCVDSEIACVDGCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVV 488

Query: 879  RVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKD 938
            +  CNTCTC S  W C+   C A C+V GD H+ TFDG+ Y+F   C+Y L ++   G  
Sbjct: 489  KEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG-- 546

Query: 939  STQDSFRVVTENVPCGTTGT-TCSKAIKIFL------------GGFELKLSHGKVEVIGT 985
                +F V  +N PCG      C +++ + L             G  L     K+    T
Sbjct: 547  ----TFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYT 602

Query: 986  DESQEVPYTIRQMGIYLVVDTDIGLVLLWDKK-TSIFINLSPEFKGRVCGLCGNFDDIAV 1044
            D++ E+    R   ++L V T++G+ +L+D++   +++ +   +     GLCG F+    
Sbjct: 603  DDAFEIR---RLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQ 659

Query: 1045 NDFATRSRSVVGDVLEFGNSWKLSPSCPDALA--PKDPCTANPFRKSWAQKQCSILHGPT 1102
            +DF +           FGNSWK   +C   ++  P DPC  +    S++ + CS+L G  
Sbjct: 660  DDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM 719

Query: 1103 FAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTP-SIC 1161
            FA C A + P  Y+E C  DAC C       C C  +A YA  C   GL V +R     C
Sbjct: 720  FAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPAC 775

Query: 1162 PLFCDYYNPEGQCEWHYQPCGVPCLRTCRN---------PRGDCLRDVWGLEGCYPKCPP 1212
             L C+           Y PC  PC RTC++           GD L     +EGC   CPP
Sbjct: 776  ALSCE-------ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPP 826

Query: 1213 EAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPG-AVVPSDKNCQSCLCTERGVECTYK 1271
            +    D     CV     P     CH  G  Y PG + +PS  +C    C +  + C  +
Sbjct: 827  DT-YLDTQADLCV-----PRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSR 877

Query: 1272 AEACVC 1277
            A A  C
Sbjct: 878  APAAAC 883



 Score =  184 bits (468), Expect = 6e-46
 Identities = 136/449 (30%), Positives = 201/449 (44%), Gaps = 68/449 (15%)

Query: 887  CDSRMWRCTDDPCL----------ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGG 936
            CD R +  T   C           + C  +G  H  TFDG  Y  +G   YTLV  H   
Sbjct: 125  CDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRH--- 181

Query: 937  KDSTQDSFRVVTENVP-CGTTGTTCSKAIKIFLGGFE-----LKLSHGKVEVIGTDESQE 990
             +    SF +   N P CG++  TCS+A+ +F  G +      +++HG + V       +
Sbjct: 182  -EPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRV-------Q 233

Query: 991  VPYT-----IRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVN 1045
            +P+      ++Q+  Y++V       L WD  ++++I +SPE  G   GLCGN +    +
Sbjct: 234  LPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 293

Query: 1046 DFATRSRSVVGDVLEFGNSWKLS-----PSCPDALAPKDPCTA-NPFRKSWAQKQCSILH 1099
            D  T S  +  DV+EF +SW+       P    +  P+ PC   NP       +QC  L 
Sbjct: 294  DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL 353

Query: 1100 GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTP 1158
             P F ACHA+V P  +  +C +D C   S GD   +C A+A YA+AC + G  +  WRT 
Sbjct: 354  RPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 411

Query: 1159 -SICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCL-RDVWGLEGCYPKCPPEAPI 1216
               C + C       +  + Y  C   C  +C +PR  C+  ++  ++GCY  CP    I
Sbjct: 412  LRQCTVHCK------EKAFTYNECIACCPASC-HPRASCVDSEIACVDGCY--CP-NGLI 461

Query: 1217 FDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACV 1276
            F++      A CP       C  HG  Y PG+VV  D  C +C CT    EC+       
Sbjct: 462  FEDGGCVAPAECP-------CEFHGTLYPPGSVVKED--CNTCTCTSGKWECSTAVCPAE 512

Query: 1277 CTYNGQRFHPGDVIYHTTDGTGGCISARC 1305
            C+        GD+ + T DG      A C
Sbjct: 513  CSVT------GDIHFTTFDGRRYTFPATC 535



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 69/285 (24%), Positives = 110/285 (38%), Gaps = 18/285 (6%)

Query: 143  VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELDTK 202
            V I      V V+  PV  P S+ G  I+ +     +     + + W H   L++   +K
Sbjct: 2179 VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASK 2238

Query: 203  YAN-KTCGLCGDFNGMPVVSELLSHNTKL----TPMEFGNLQKMDDPTEQCQDPVPEPPR 257
             +  +  GLCG  +G       L   + +     P  F +  ++             P  
Sbjct: 2239 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298

Query: 258  NCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQ 317
              +T    C  ++  + FS C   V   S+ E       +  DT  +   C  L  Y   
Sbjct: 2299 CATTDCSPCLRMVSNRTFSACHRFVPPESFCEL------WIRDTKYVQQPCVALTVYVAM 2352

Query: 318  CTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD--TCSNQEHSRACEDHCVA---GC 372
            C H   +  +WR  D+CP  C ++  Y  C + C    TC +        +HC     GC
Sbjct: 2353 C-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2411

Query: 373  FCPEGTVLDDIGQTGCVPVSKCACVYN-GAAYAPGATYSTDCTNC 416
             C EGT+L       C+P +KCAC  + G   A G T+++  + C
Sbjct: 2412 VCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2456



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 79/334 (23%), Positives = 126/334 (37%), Gaps = 48/334 (14%)

Query: 875  GQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHC 934
            G  +RVG + C     +W C        C+++ D  ++TFDG   +   +  Y L Q+  
Sbjct: 2091 GLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSP- 2141

Query: 935  GGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGKVEVIGTDESQEV--- 991
              +  T       + N+        C   + +     ++ +     +V  T + Q V   
Sbjct: 2142 -DEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKV--TVDLQPVWPP 2198

Query: 992  ----PYTIRQMGIYLVVDTDIGLVLLWDKKTSIFI-NLSPEFKGRVCGLCGNFDDIAVND 1046
                 + I   G   ++ T   + + W   + + I   S   K +  GLCG  D  A ND
Sbjct: 2199 VSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAAND 2258

Query: 1047 FATRSRSVVG---DVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCS----ILH 1099
               +  SVVG   D   F +SW++    P +L         P   S A   CS    ++ 
Sbjct: 2259 LTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQTRFRP--DSCATTDCSPCLRMVS 2312

Query: 1100 GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPS 1159
              TF+ACH  V P  + E  + D             C A+  Y   CH+  +C+ WR   
Sbjct: 2313 NRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSD 2366

Query: 1160 ICPLFCDYYNPEGQCEWHYQPCGVPC--LRTCRN 1191
             CP  C         +  YQ C   C   +TC++
Sbjct: 2367 YCPFLC-------SSDSTYQACVTACEPPKTCQD 2393



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 148/661 (22%), Positives = 225/661 (34%), Gaps = 108/661 (16%)

Query: 386  TGCVPVSKCACV-----------YNGAAYAPGATYSTDCTNCTCS---GGRWSCQEVPCP 431
            T CVP+++  CV            N + + P       C     +   GG   C    C 
Sbjct: 2049 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECA 2108

Query: 432  GTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD---SETCLK 488
              CS+     F TFDG    +  +  Y+L++  D      + + +   L        CL 
Sbjct: 2109 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2168

Query: 489  SVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQ 548
             + ++    Q V + + + +V ++      P+S     I      ++I   S    + +Q
Sbjct: 2169 MLNMTHLAHQ-VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQ 2224

Query: 549  LVPTMQLFMQLAPKL-RGQTCGLCGNFNSIQADDFRTLSGVVEATA---AAFFNTFKTQA 604
             + +  L +  A K  + Q  GLCG  +   A+D     G V   A   A F ++++  +
Sbjct: 2225 WLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPS 2284

Query: 605  ACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNC 664
            +  ++  +   P S +  +        S  T     F  CH  V P ++    + DT   
Sbjct: 2285 SLTSVGQTRFRPDSCATTDCSPCLRMVSNRT-----FSACHRFVPPESFCELWIRDTKYV 2339

Query: 665  ERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQP--TCR 722
            ++     C AL+ YV  C    V +   R   C      C    TY   V+ C+P  TC+
Sbjct: 2340 QQP----CVALTVYVAMCHKFHVCIEWRRSDYCP---FLCSSDSTYQACVTACEPPKTCQ 2392

Query: 723  SLSEGDITCSVGFIPVDGCICPKGTFLD--DTGKCVQASNCPCY-HRGSMIPNGESVHDS 779
                G +      +  +GC+C +GT L    +  C+  + C C    G     GE+ + S
Sbjct: 2393 DGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSS 2452

Query: 780  GAICTCTHGKLSCIGGQAPAPV---CAAPM---------VFFDCRNATPGDTGAGC---Q 824
             + C C H    C       PV   C +P          V        P   G  C   Q
Sbjct: 2453 LSGC-CQH---QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQ 2508

Query: 825  KSCHTLDMTC------------------YSPQC---------VPGCVCPDGLVADGEG-G 856
              C  L  TC                  YS +C         VP C     L+    G  
Sbjct: 2509 TLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDS 2568

Query: 857  CITA-----EDCP-----CVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPC---LATC 903
            C T+      DCP     C   EA      T  + C    C    +RC    C    A  
Sbjct: 2569 CCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALV 2628

Query: 904  AVYGDGHYLTFDGQSYSFNGDCEYTLVQN-HCGGKDSTQDSFRVVTENVPCGTTGTTCSK 962
             V+       +     S   DC+   V   H   K    + F    ENV CG     C K
Sbjct: 2629 EVWSPDRCCPYK----SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENV-CGCAKYECVK 2683

Query: 963  A 963
            A
Sbjct: 2684 A 2684



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 104/450 (23%), Positives = 147/450 (32%), Gaps = 73/450 (16%)

Query: 1174 CEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCV--ATCPTP 1231
            CEW Y  C  PC +TCR+PR    RDV     C P C P   + DE   +CV    C  P
Sbjct: 1408 CEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVC-PTPQVLDEVTQRCVYLEDCVEP 1466

Query: 1232 PLPPRCHVHGKSYRP---GAVVPSDKNCQ------------------SCLCTERGVECTY 1270
             +       G    P   G   PSD+  Q                  + L T      T 
Sbjct: 1467 AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTA 1526

Query: 1271 KAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFS 1330
              E  V     Q      +    +    G   +      T      P +P +   P    
Sbjct: 1527 TEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQ 1586

Query: 1331 FSTPPLVVSSTHTP--------SNGPSSAHTGPPSSAWP------TTAG-------TSPR 1369
              TP +V  +  T         S   + +   PP+  +P      T  G       T+P 
Sbjct: 1587 TPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPL 1646

Query: 1370 TRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCES---PRS 1426
                TAS S  PV       SP      P   T SG    +  L     +V      P+ 
Sbjct: 1647 QPSLTASPSSRPVA------SPGAISRSP---TSSGSHKAV--LTPAVTKVISRTGVPQP 1695

Query: 1427 VECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLA--CSTS 1484
             + ++  +P  PL   G   +  P   L  R+ E             Q   P+    S  
Sbjct: 1696 TQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQ---PMGSPASPQ 1752

Query: 1485 SSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTA----RTTPAPGTATSVKKTFSTP 1540
              P  + PP  ++ T       + P  TP   SLSTA      TP     ++      + 
Sbjct: 1753 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1812

Query: 1541 SPP----PVPATSTSS-MSTTTPGTSVVSS 1565
             PP    P+    TS+ ++T  P  SV+++
Sbjct: 1813 LPPDTSLPLAKVGTSAPVATPGPKASVITT 1842



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 51/186 (27%), Positives = 71/186 (38%), Gaps = 33/186 (17%)

Query: 1848 PVTST--PVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYA------H 1899
            PVT+T  PV +P         PTQ+T       T + +    T +P +    A      H
Sbjct: 1523 PVTATEEPVVSPG--------PTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1574

Query: 1900 TTSTTSAPTARTTSAP--------TTRTT---SASPASTTSGPGNTPSPVPTTSTISAPT 1948
            T  ++S P A  T  P        TTR T   + SP  T S   + P+P     T +   
Sbjct: 1575 TPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSS-RSPPAPRFPLMTKAVTV 1633

Query: 1949 TSITSAPTTSTTSAP--TSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTT 2006
                S P  +T   P  T+S +S P  S  +   S T+S    +  +   T   S  G  
Sbjct: 1634 RGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV- 1692

Query: 2007 PSPVPT 2012
              P PT
Sbjct: 1693 --PQPT 1696



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 55/200 (27%), Positives = 78/200 (39%), Gaps = 25/200 (12%)

Query: 1826 GPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTT 1885
            GP +  L   + +   + P G   T +P +   T S  AI  T  +SS        L   
Sbjct: 1535 GPTQTTLQQPLELTASQLPAG--PTESPASKGVTASLLAIPHTPESSS--------LPVA 1584

Query: 1886 STTSTPQTSTTYAHTTSTT----SAP--TARTTSAPTTRTTSASPASTTSGPGNTPSPVP 1939
              T TP   +    TT  T     +P  T  + S P  R    + A T  G G+ P  V 
Sbjct: 1585 LQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLP--VR 1642

Query: 1940 TTSTISAPTTSITSAPTTST---TSAPTSSTTSAPTTSTTSAPTSSTTSSPQTS---TTS 1993
            TT    + T S +S P  S    + +PTSS +     +       S T  PQ +   + S
Sbjct: 1643 TTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSAS 1702

Query: 1994 APTTSTTSGPGTTPSPVPTT 2013
            +P+T  T   GT    VP +
Sbjct: 1703 SPSTPLTVA-GTAAEQVPVS 1721



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 51/195 (26%), Positives = 72/195 (36%), Gaps = 31/195 (15%)

Query: 1843 TPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTS 1902
            TP    +T++P + P    G AIS + ++S   K+  T  VT   + T     T A + S
Sbjct: 1644 TPLQPSLTASPSSRPVASPG-AISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSAS 1702

Query: 1903 TTSAPTARTTSAPTTRTTSASPASTTS------------------GPGNTPSPVPTTSTI 1944
            + S P   T +         SP +T S                  G   +P P P  S  
Sbjct: 1703 SPSTPL--TVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAP 1760

Query: 1945 SAP---TTSITSAPTTST-TSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTST- 1999
              P   TT  T +P     T A  S +T+    + T   +  +T   Q  +   P TS  
Sbjct: 1761 PRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLP 1820

Query: 2000 -----TSGPGTTPSP 2009
                 TS P  TP P
Sbjct: 1821 LAKVGTSAPVATPGP 1835



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 81/357 (22%), Positives = 121/357 (33%), Gaps = 49/357 (13%)

Query: 1684 PKTVATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNC 1743
            P   AT  P   P    TQTT    +   +++ P      GPT +  ++G  T  +    
Sbjct: 1522 PPVTATEEPVVSP--GPTQTTLQQPLELTASQLPA-----GPTESPASKGV-TASLLAIP 1573

Query: 1744 HPRCTWTKWFDVDFPSPGPHGGDKETYN-NIIRSGEK---ICRRPEEITRLQCRAKS--- 1796
            H   + +    +  P+PG   G  ET    +I +G     +  R     R     K+   
Sbjct: 1574 HTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTV 1633

Query: 1797 -------------HPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCET 1843
                          P ++     + V      G + R+    G  K  L   V  +   T
Sbjct: 1634 RGHGSLPVRTTPLQPSLTASPSSRPVA---SPGAISRSPTSSGSHKAVLTPAVTKVISRT 1690

Query: 1844 PRGCPVTSTPVTAPSTPSGRA-ISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTS 1902
                P  +   ++PSTP   A  +  Q   S   +R+  +V ++       S       S
Sbjct: 1691 GVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPAS 1750

Query: 1903 TTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSA 1962
                P       P   TT A     T  P   P   P  +++S  T  + + P  S  S 
Sbjct: 1751 PQPHPLPSAPPRPAQHTTMA-----TRSPA-LPPETPAAASLSTATDGLAATPFMSLEST 1804

Query: 1963 PTSSTTSA--PTTST------TSAPTSSTTSSPQTSTTSAP-TTSTTSGPGTTPSPV 2010
              S   S   P TS       TSAP +  T  P+ S  + P     T+ P  T SPV
Sbjct: 1805 RPSQLLSGLPPDTSLPLAKVGTSAPVA--TPGPKASVITTPLQPQATTLPAQTLSPV 1859



 Score = 40.8 bits (94), Expect = 0.014
 Identities = 40/171 (23%), Positives = 64/171 (37%), Gaps = 19/171 (11%)

Query: 1844 PRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST 1903
            P G P +  P   PS P              + ++ TT+ T S    P+T    + +T+T
Sbjct: 1744 PMGSPASPQPHPLPSAPP-------------RPAQHTTMATRSPALPPETPAAASLSTAT 1790

Query: 1904 TSAPTARTTSAPTTRTTSASPASTTSG-PGNTPSPVPTTSTISAPTTSITSAPTTSTTSA 1962
                     S  +TR     P+   SG P +T  P+    T +   T    A   +T   
Sbjct: 1791 DGLAATPFMSLESTR-----PSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQ 1845

Query: 1963 PTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
            P ++T  A T S     T +  +     T  AP  + T+      + +PT+
Sbjct: 1846 PQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTS 1896



 Score = 39.3 bits (90), Expect = 0.039
 Identities = 47/167 (28%), Positives = 64/167 (38%), Gaps = 21/167 (12%)

Query: 1850 TSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTA 1909
            TS PV  P   +    +P Q  ++   ++T + V   T +    + T AH  +  + P A
Sbjct: 1826 TSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPA----AMTQAHPPTHIAPPAA 1881

Query: 1910 RTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTS--APTSST 1967
             T  AP     +  P S     G  P    T S +S         P  STT   A  S  
Sbjct: 1882 GT--APGLLLGATLPTS-----GVLPVAEGTASMVSV-------VPRKSTTGKVAILSKQ 1927

Query: 1968 TSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSG-PGTTPSPVPTT 2013
             S PT+   SA    T  +P TS    P  +   G    T  PVPT+
Sbjct: 1928 VSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTS 1974



 Score = 35.8 bits (81), Expect = 0.44
 Identities = 43/169 (25%), Positives = 59/169 (34%), Gaps = 13/169 (7%)

Query: 1855 TAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST-----TSAPTA 1909
            T P +      S  +   S +  RT T     T + P T+      T+T     +  PT 
Sbjct: 1479 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQ 1538

Query: 1910 RTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAP-TTSITSAPTTSTTSAPTSSTT 1968
             T   P   T S  PA  T  P    S   T S ++ P T   +S P    T  P   + 
Sbjct: 1539 TTLQQPLELTASQLPAGPTESPA---SKGVTASLLAIPHTPESSSLPVALQTPTPGMVSG 1595

Query: 1969 SAPTTSTTSAPTSSTTSSPQTSTTSAP----TTSTTSGPGTTPSPVPTT 2013
            +  TT  T     S   +  + +  AP     T   +  G    PV TT
Sbjct: 1596 AMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1644



 Score = 32.7 bits (73), Expect = 3.7
 Identities = 31/104 (29%), Positives = 45/104 (43%), Gaps = 16/104 (15%)

Query: 1477 TPLACSTSSSPAQTT---PPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSV 1533
            TP     S+ P+Q     PP TS        G+SAP +TPG  +  +  TTP    AT++
Sbjct: 1796 TPFMSLESTRPSQLLSGLPPDTS--LPLAKVGTSAPVATPGPKA--SVITTPLQPQATTL 1851

Query: 1534 KKTFSTPSPPPVPATSTSS---------MSTTTPGTSVVSSKPT 1568
                 +P  P  PA  T +          + T PG  + ++ PT
Sbjct: 1852 PAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPT 1895



 Score = 31.6 bits (70), Expect = 8.2
 Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 13/68 (19%)

Query: 327  DWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQT 386
            +WR  D C   C     +  CR P A +C +    R+C         CP   VLD++ Q 
Sbjct: 1409 EWRY-DACASPC-----FQTCRDPRAASCRDVPRGRSCVP------VCPTPQVLDEVTQR 1456

Query: 387  GCVPVSKC 394
             CV +  C
Sbjct: 1457 -CVYLEDC 1463



 Score = 31.6 bits (70), Expect = 8.2
 Identities = 46/182 (25%), Positives = 60/182 (32%), Gaps = 34/182 (18%)

Query: 1848 PVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAP 1907
            P T     A  T  G  +  T  TS        T    S      T+   A  +   S P
Sbjct: 1872 PPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLP 1931

Query: 1908 TARTTSA---PTTRTTSASP------ASTTSGPGNTPSPVPTTSTIS------APTTSI- 1951
            T+   SA   PT  T + S       A        T  PVPT+  +S      AP  S+ 
Sbjct: 1932 TSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSML 1991

Query: 1952 -----------TSA-------PTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTS 1993
                       TSA       P    T+ P+  +  A +     A   +TT+   TSTT 
Sbjct: 1992 VLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTC 2051

Query: 1994 AP 1995
             P
Sbjct: 2052 VP 2053


>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score =  612 bits (1577), Expect = e-174
 Identities = 381/1126 (33%), Positives = 548/1126 (48%), Gaps = 65/1126 (5%)

Query: 80   VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQE--SAAPTLSRV- 136
            +C  WG  H +TFDG  +   G  +Y          + F+IQ+    +  S+  T SR  
Sbjct: 78   ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137

Query: 137  -LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSL 195
             L  V    I L K  V   G  V LP       +QQ + Y  V  +    L W+   ++
Sbjct: 138  SLFFVGEQEIHLAK-EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAV 196

Query: 196  LLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL---QKMDDPTEQCQD 250
             +++  +    T GLCG+ N  P   +L++ + KLT   +EF +    Q  + P      
Sbjct: 197  YIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255

Query: 251  PVPEPP---RNCSTGFGI---CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304
             +P PP   +N  T  G+   CE LL    F  C A V    +  +C  DLC  +    +
Sbjct: 256  SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLC--QSMGDV 312

Query: 305  SCVCHTLAEYSRQCTHAGGLPQDWRGP-DFCPQKCPNN-MQYHECRSPCADTCSNQEHSR 362
            +  C  LAEY+R C  AG   Q WR     C   C      Y+EC + C  +C  +    
Sbjct: 313  ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCV 372

Query: 363  ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGR 422
              E  CV GC+CP G + +D    GCV  ++C C ++G  Y PG+    DC  CTC+ G+
Sbjct: 373  DSEIACVDGCYCPNGLIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGK 429

Query: 423  WSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD 482
            W C    CP  CSV G  HF+TFDG++YT    C Y+L K   S  FTV  +   CGL  
Sbjct: 430  WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQ 489

Query: 483  SETCLKSVTLSL-DGVQTVVVIKASGEVFLNQIYTQLPISAANV-TIFRPSTFFIIAQTS 540
               C++SV++ L    +  V +  +G+V L   Y  +P    +   I R S+ F+  +T+
Sbjct: 490  DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 549

Query: 541  LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600
            +G+++ L     ++L++Q+  +    T GLCG FN    DDF +  GV E+T   F N++
Sbjct: 550  VGVRV-LYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSW 608

Query: 601  KTQAAC-PNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMF 659
            KT +AC P +  S  DPC + ++   Y+   CS LT     F  C A + P  Y+  C  
Sbjct: 609  KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRR 666

Query: 660  DTCNCERSEDCLCAALSSYVHACAAKGVQLG-GWRDGVCTKPMTTCPKSMTYHYHVSTCQ 718
            D C C   + CLCA L+ Y H C   G+ +    R   C     +C  S  Y   V+ C 
Sbjct: 667  DACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACA---LSCEASKEYSPCVAPCG 721

Query: 719  PTCRSLSEGDITCSVGFIP-------VDGCICPKGTFLDDTGK-CVQASNCPCYHRGSMI 770
             TC+ L+  +  C V           V+GC CP  T+LD     CV  + C C+ +G   
Sbjct: 722  RTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780

Query: 771  PNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPG---DTGAGCQKSC 827
            P G+S   S   C C  G +SC   +APA  C A  VF +C +            C++  
Sbjct: 781  PPGDSDIPSLGHCHCKDGVMSC-DSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQL 839

Query: 828  HTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTC 887
              L ++   P C+ GC CP GL+  G+  C   E+CPC      Y  G  +   C+TC C
Sbjct: 840  LNLSVSARGP-CLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVC 897

Query: 888  DSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVV 947
                ++CT  PC +TC  YGD HY TFDG  + F G C+  LV      K ++  SF V+
Sbjct: 898  QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVI 951

Query: 948  TENVPCGTTGTTCSKAIKIFLGG----FELKLSHGKVEVIGTDESQEVPYTIRQMGIYLV 1003
             ENV C ++G  C K I I +G     F+    +   E    D+ QEV +T R     LV
Sbjct: 952  VENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESF-LDDKQEV-HTWRVGFFTLV 1009

Query: 1004 VDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGN 1063
                  + LLWD++T++ +   P+++G++ GLCGNFD   +N+  T     + +  EFG+
Sbjct: 1010 HFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGS 1069

Query: 1064 SWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDA 1123
            SW  +  CPD L P+D C  NP R+ +A+K+CSIL    F  CH  V+   +Y  C+ D 
Sbjct: 1070 SWA-AVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1128

Query: 1124 CACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYN 1169
            C C  GGDCECFC +V+AYA  C + G+ V WRTP +CP  CD++N
Sbjct: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174



 Score =  231 bits (590), Expect = 4e-60
 Identities = 152/486 (31%), Positives = 221/486 (45%), Gaps = 62/486 (12%)

Query: 821  AGCQKSCHTLDMTCYSPQ--CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTI 878
            A C  SCH    +C   +  CV GC CP+GL+ + +GGC+   +CPC  +   Y  G  +
Sbjct: 359  ACCPASCHPR-ASCVDSEIACVDGCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVV 416

Query: 879  RVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKD 938
            +  CNTCTC S  W C+   C A C+V GD H+ TFDG+ Y+F   C+Y L ++   G  
Sbjct: 417  KEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG-- 474

Query: 939  STQDSFRVVTENVPCGTTGT-TCSKAIKIFL------------GGFELKLSHGKVEVIGT 985
                +F V  +N PCG      C +++ + L             G  L     K+    T
Sbjct: 475  ----TFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYT 530

Query: 986  DESQEVPYTIRQMGIYLVVDTDIGLVLLWDKK-TSIFINLSPEFKGRVCGLCGNFDDIAV 1044
            D++ E+    R   ++L V T++G+ +L+D++   +++ +   +     GLCG F+    
Sbjct: 531  DDAFEIR---RLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQ 587

Query: 1045 NDFATRSRSVVGDVLEFGNSWKLSPSCPDALA--PKDPCTANPFRKSWAQKQCSILHGPT 1102
            +DF +           FGNSWK   +C   ++  P DPC  +    S++ + CS+L G  
Sbjct: 588  DDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM 647

Query: 1103 FAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTP-SIC 1161
            FA C A + P  Y+E C  DAC C       C C  +A YA  C   GL V +R     C
Sbjct: 648  FAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPAC 703

Query: 1162 PLFCDYYNPEGQCEWHYQPCGVPCLRTCRN---------PRGDCLRDVWGLEGCYPKCPP 1212
             L C+           Y PC  PC RTC++           GD L     +EGC   CPP
Sbjct: 704  ALSCE-------ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPP 754

Query: 1213 EAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPG-AVVPSDKNCQSCLCTERGVECTYK 1271
            +    D     CV     P     CH  G  Y PG + +PS  +C    C +  + C  +
Sbjct: 755  DT-YLDTQADLCV-----PRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSR 805

Query: 1272 AEACVC 1277
            A A  C
Sbjct: 806  APAAAC 811



 Score =  184 bits (468), Expect = 6e-46
 Identities = 136/449 (30%), Positives = 201/449 (44%), Gaps = 68/449 (15%)

Query: 887  CDSRMWRCTDDPCL----------ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGG 936
            CD R +  T   C           + C  +G  H  TFDG  Y  +G   YTLV  H   
Sbjct: 53   CDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRH--- 109

Query: 937  KDSTQDSFRVVTENVP-CGTTGTTCSKAIKIFLGGFE-----LKLSHGKVEVIGTDESQE 990
             +    SF +   N P CG++  TCS+A+ +F  G +      +++HG + V       +
Sbjct: 110  -EPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRV-------Q 161

Query: 991  VPYT-----IRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVN 1045
            +P+      ++Q+  Y++V       L WD  ++++I +SPE  G   GLCGN +    +
Sbjct: 162  LPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221

Query: 1046 DFATRSRSVVGDVLEFGNSWKLS-----PSCPDALAPKDPCTA-NPFRKSWAQKQCSILH 1099
            D  T S  +  DV+EF +SW+       P    +  P+ PC   NP       +QC  L 
Sbjct: 222  DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL 281

Query: 1100 GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTP 1158
             P F ACHA+V P  +  +C +D C   S GD   +C A+A YA+AC + G  +  WRT 
Sbjct: 282  RPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 339

Query: 1159 -SICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCL-RDVWGLEGCYPKCPPEAPI 1216
               C + C       +  + Y  C   C  +C +PR  C+  ++  ++GCY  CP    I
Sbjct: 340  LRQCTVHCK------EKAFTYNECIACCPASC-HPRASCVDSEIACVDGCY--CP-NGLI 389

Query: 1217 FDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACV 1276
            F++      A CP       C  HG  Y PG+VV  D  C +C CT    EC+       
Sbjct: 390  FEDGGCVAPAECP-------CEFHGTLYPPGSVVKED--CNTCTCTSGKWECSTAVCPAE 440

Query: 1277 CTYNGQRFHPGDVIYHTTDGTGGCISARC 1305
            C+        GD+ + T DG      A C
Sbjct: 441  CSVT------GDIHFTTFDGRRYTFPATC 463



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 69/285 (24%), Positives = 110/285 (38%), Gaps = 18/285 (6%)

Query: 143  VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELDTK 202
            V I      V V+  PV  P S+ G  I+ +     +     + + W H   L++   +K
Sbjct: 2107 VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASK 2166

Query: 203  YAN-KTCGLCGDFNGMPVVSELLSHNTKL----TPMEFGNLQKMDDPTEQCQDPVPEPPR 257
             +  +  GLCG  +G       L   + +     P  F +  ++             P  
Sbjct: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226

Query: 258  NCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQ 317
              +T    C  ++  + FS C   V   S+ E       +  DT  +   C  L  Y   
Sbjct: 2227 CATTDCSPCLRMVSNRTFSACHRFVPPESFCEL------WIRDTKYVQQPCVALTVYVAM 2280

Query: 318  CTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD--TCSNQEHSRACEDHCVA---GC 372
            C H   +  +WR  D+CP  C ++  Y  C + C    TC +        +HC     GC
Sbjct: 2281 C-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2339

Query: 373  FCPEGTVLDDIGQTGCVPVSKCACVYN-GAAYAPGATYSTDCTNC 416
             C EGT+L       C+P +KCAC  + G   A G T+++  + C
Sbjct: 2340 VCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2384



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 79/334 (23%), Positives = 126/334 (37%), Gaps = 48/334 (14%)

Query: 875  GQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHC 934
            G  +RVG + C     +W C        C+++ D  ++TFDG   +   +  Y L Q+  
Sbjct: 2019 GLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSP- 2069

Query: 935  GGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGKVEVIGTDESQEV--- 991
              +  T       + N+        C   + +     ++ +     +V  T + Q V   
Sbjct: 2070 -DEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKV--TVDLQPVWPP 2126

Query: 992  ----PYTIRQMGIYLVVDTDIGLVLLWDKKTSIFI-NLSPEFKGRVCGLCGNFDDIAVND 1046
                 + I   G   ++ T   + + W   + + I   S   K +  GLCG  D  A ND
Sbjct: 2127 VSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAAND 2186

Query: 1047 FATRSRSVVG---DVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCS----ILH 1099
               +  SVVG   D   F +SW++    P +L         P   S A   CS    ++ 
Sbjct: 2187 LTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQTRFRP--DSCATTDCSPCLRMVS 2240

Query: 1100 GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPS 1159
              TF+ACH  V P  + E  + D             C A+  Y   CH+  +C+ WR   
Sbjct: 2241 NRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSD 2294

Query: 1160 ICPLFCDYYNPEGQCEWHYQPCGVPC--LRTCRN 1191
             CP  C         +  YQ C   C   +TC++
Sbjct: 2295 YCPFLC-------SSDSTYQACVTACEPPKTCQD 2321



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 148/661 (22%), Positives = 225/661 (34%), Gaps = 108/661 (16%)

Query: 386  TGCVPVSKCACV-----------YNGAAYAPGATYSTDCTNCTCS---GGRWSCQEVPCP 431
            T CVP+++  CV            N + + P       C     +   GG   C    C 
Sbjct: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECA 2036

Query: 432  GTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD---SETCLK 488
              CS+     F TFDG    +  +  Y+L++  D      + + +   L        CL 
Sbjct: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096

Query: 489  SVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQ 548
             + ++    Q V + + + +V ++      P+S     I      ++I   S    + +Q
Sbjct: 2097 MLNMTHLAHQ-VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQ 2152

Query: 549  LVPTMQLFMQLAPKL-RGQTCGLCGNFNSIQADDFRTLSGVVEATA---AAFFNTFKTQA 604
             + +  L +  A K  + Q  GLCG  +   A+D     G V   A   A F ++++  +
Sbjct: 2153 WLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPS 2212

Query: 605  ACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNC 664
            +  ++  +   P S +  +        S  T     F  CH  V P ++    + DT   
Sbjct: 2213 SLTSVGQTRFRPDSCATTDCSPCLRMVSNRT-----FSACHRFVPPESFCELWIRDTKYV 2267

Query: 665  ERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQP--TCR 722
            ++     C AL+ YV  C    V +   R   C      C    TY   V+ C+P  TC+
Sbjct: 2268 QQP----CVALTVYVAMCHKFHVCIEWRRSDYCP---FLCSSDSTYQACVTACEPPKTCQ 2320

Query: 723  SLSEGDITCSVGFIPVDGCICPKGTFLD--DTGKCVQASNCPCY-HRGSMIPNGESVHDS 779
                G +      +  +GC+C +GT L    +  C+  + C C    G     GE+ + S
Sbjct: 2321 DGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSS 2380

Query: 780  GAICTCTHGKLSCIGGQAPAPV---CAAPM---------VFFDCRNATPGDTGAGC---Q 824
             + C C H    C       PV   C +P          V        P   G  C   Q
Sbjct: 2381 LSGC-CQH---QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQ 2436

Query: 825  KSCHTLDMTC------------------YSPQC---------VPGCVCPDGLVADGEG-G 856
              C  L  TC                  YS +C         VP C     L+    G  
Sbjct: 2437 TLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDS 2496

Query: 857  CITA-----EDCP-----CVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPC---LATC 903
            C T+      DCP     C   EA      T  + C    C    +RC    C    A  
Sbjct: 2497 CCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALV 2556

Query: 904  AVYGDGHYLTFDGQSYSFNGDCEYTLVQN-HCGGKDSTQDSFRVVTENVPCGTTGTTCSK 962
             V+       +     S   DC+   V   H   K    + F    ENV CG     C K
Sbjct: 2557 EVWSPDRCCPYK----SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENV-CGCAKYECVK 2611

Query: 963  A 963
            A
Sbjct: 2612 A 2612



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 106/450 (23%), Positives = 150/450 (33%), Gaps = 73/450 (16%)

Query: 1174 CEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCV--ATCPTP 1231
            CEW Y  C  PC +TCR+PR    RDV  +EGC P C P   + DE   +CV    C  P
Sbjct: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVC-PTPQVLDEVTQRCVYLEDCVEP 1394

Query: 1232 PLPPRCHVHGKSYRP---GAVVPSDKNCQ------------------SCLCTERGVECTY 1270
             +       G    P   G   PSD+  Q                  + L T      T 
Sbjct: 1395 AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTA 1454

Query: 1271 KAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFS 1330
              E  V     Q      +    +    G   +      T      P +P +   P    
Sbjct: 1455 TEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQ 1514

Query: 1331 FSTPPLVVSSTHTP--------SNGPSSAHTGPPSSAWP------TTAG-------TSPR 1369
              TP +V  +  T         S   + +   PP+  +P      T  G       T+P 
Sbjct: 1515 TPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPP 1574

Query: 1370 TRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCES---PRS 1426
                TAS S  PV       SP      P   T SG    +  L     +V      P+ 
Sbjct: 1575 QPSLTASPSSRPVA------SPGAISRSP---TSSGSHKAV--LTPAVTKVISRTGVPQP 1623

Query: 1427 VECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLA--CSTS 1484
             + ++  +P  PL   G   +  P   L  R+ E             Q   P+    S  
Sbjct: 1624 TQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQ---PMGSPASPQ 1680

Query: 1485 SSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTA----RTTPAPGTATSVKKTFSTP 1540
              P  + PP  ++ T       + P  TP   SLSTA      TP     ++      + 
Sbjct: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740

Query: 1541 SPP----PVPATSTSS-MSTTTPGTSVVSS 1565
             PP    P+    TS+ ++T  P  SV+++
Sbjct: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITT 1770



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 51/186 (27%), Positives = 71/186 (38%), Gaps = 33/186 (17%)

Query: 1848 PVTST--PVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYA------H 1899
            PVT+T  PV +P         PTQ+T       T + +    T +P +    A      H
Sbjct: 1451 PVTATEEPVVSPG--------PTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1502

Query: 1900 TTSTTSAPTARTTSAP--------TTRTT---SASPASTTSGPGNTPSPVPTTSTISAPT 1948
            T  ++S P A  T  P        TTR T   + SP  T S   + P+P     T +   
Sbjct: 1503 TPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSS-RSPPAPRFPLMTKAVTV 1561

Query: 1949 TSITSAPTTSTTSAP--TSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTT 2006
                S P  +T   P  T+S +S P  S  +   S T+S    +  +   T   S  G  
Sbjct: 1562 RGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV- 1620

Query: 2007 PSPVPT 2012
              P PT
Sbjct: 1621 --PQPT 1624



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 73/344 (21%), Positives = 117/344 (34%), Gaps = 47/344 (13%)

Query: 1687 VATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPT------ATSVTQGTHTTPVT 1740
            VA   PTP       +TT  T +  A +   T +SR  P         +VT   H +   
Sbjct: 1511 VALQTPTPGMVSGAMETTRVTVI-FAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPV 1569

Query: 1741 RNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRL---------- 1790
            R   P+ + T       PS  P         +   SG         +T++          
Sbjct: 1570 RTTPPQPSLTA-----SPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPT 1624

Query: 1791 QCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVT 1850
            Q ++ S P   +   G   +      L  R+       ++ L+ E        P G P +
Sbjct: 1625 QAQSASSPSTPLTVAGTAAEQVPVSPLATRS------LEIVLSTEKGEAGHSQPMGSPAS 1678

Query: 1851 STPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTAR 1910
              P   PS P              + ++ TT+ T S    P+T    + +T+T       
Sbjct: 1679 PQPHPLPSAPP-------------RPAQHTTMATRSPALPPETPAAASLSTATDGLAATP 1725

Query: 1911 TTSAPTTRTTSASPASTTSG-PGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTS 1969
              S  +TR     P+   SG P +T  P+    T +   T    A   +T   P ++T  
Sbjct: 1726 FMSLESTR-----PSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLP 1780

Query: 1970 APTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
            A T S     T +  +     T  AP  + T+      + +PT+
Sbjct: 1781 AQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTS 1824



 Score = 39.3 bits (90), Expect = 0.039
 Identities = 47/167 (28%), Positives = 64/167 (38%), Gaps = 21/167 (12%)

Query: 1850 TSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTA 1909
            TS PV  P   +    +P Q  ++   ++T + V   T +    + T AH  +  + P A
Sbjct: 1754 TSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPA----AMTQAHPPTHIAPPAA 1809

Query: 1910 RTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTS--APTSST 1967
             T  AP     +  P S     G  P    T S +S         P  STT   A  S  
Sbjct: 1810 GT--APGLLLGATLPTS-----GVLPVAEGTASMVSV-------VPRKSTTGKVAILSKQ 1855

Query: 1968 TSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSG-PGTTPSPVPTT 2013
             S PT+   SA    T  +P TS    P  +   G    T  PVPT+
Sbjct: 1856 VSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTS 1902



 Score = 35.8 bits (81), Expect = 0.44
 Identities = 40/185 (21%), Positives = 60/185 (32%), Gaps = 35/185 (18%)

Query: 1855 TAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST-----TSAPTA 1909
            T P +      S  +   S +  RT T     T + P T+      T+T     +  PT 
Sbjct: 1407 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQ 1466

Query: 1910 RTTSAPTTRTTSASPASTTSGPG------------NTPSPVPTTSTISAPTTSITSAPTT 1957
             T   P   T S  PA  T  P             +TP        +  PT  + S    
Sbjct: 1467 TTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAME 1526

Query: 1958 STTSAPTSSTTSAPTTSTTSAPTSS------------------TTSSPQTSTTSAPTTST 1999
            +T      + +   T S+ S P                      T+ PQ S T++P++  
Sbjct: 1527 TTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRP 1586

Query: 2000 TSGPG 2004
             + PG
Sbjct: 1587 VASPG 1591



 Score = 35.8 bits (81), Expect = 0.44
 Identities = 33/129 (25%), Positives = 42/129 (32%), Gaps = 16/129 (12%)

Query: 1885 TSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTI 1944
            T +   PQ S     T      PT R    P    T+A     T+      SP PT +T+
Sbjct: 1416 TPSDEEPQLSQESPRT------PTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTL 1469

Query: 1945 SAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPG 2004
              P     S      T +P S   +A   +    P SS          S P    T  PG
Sbjct: 1470 QQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESS----------SLPVALQTPTPG 1519

Query: 2005 TTPSPVPTT 2013
                 + TT
Sbjct: 1520 MVSGAMETT 1528



 Score = 34.7 bits (78), Expect = 0.97
 Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 3/54 (5%)

Query: 343  QYHECRSPCADTCSNQEHSRACEDHCVAGC--FCPEGTVLDDIGQTGCVPVSKC 394
            +Y  C SPC  TC +   +   +   V GC   CP   VLD++ Q  CV +  C
Sbjct: 1339 RYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQR-CVYLEDC 1391



 Score = 32.7 bits (73), Expect = 3.7
 Identities = 31/104 (29%), Positives = 45/104 (43%), Gaps = 16/104 (15%)

Query: 1477 TPLACSTSSSPAQTT---PPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSV 1533
            TP     S+ P+Q     PP TS        G+SAP +TPG  +  +  TTP    AT++
Sbjct: 1724 TPFMSLESTRPSQLLSGLPPDTS--LPLAKVGTSAPVATPGPKA--SVITTPLQPQATTL 1779

Query: 1534 KKTFSTPSPPPVPATSTSS---------MSTTTPGTSVVSSKPT 1568
                 +P  P  PA  T +          + T PG  + ++ PT
Sbjct: 1780 PAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPT 1823



 Score = 31.6 bits (70), Expect = 8.2
 Identities = 46/182 (25%), Positives = 60/182 (32%), Gaps = 34/182 (18%)

Query: 1848 PVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAP 1907
            P T     A  T  G  +  T  TS        T    S      T+   A  +   S P
Sbjct: 1800 PPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLP 1859

Query: 1908 TARTTSA---PTTRTTSASP------ASTTSGPGNTPSPVPTTSTIS------APTTSI- 1951
            T+   SA   PT  T + S       A        T  PVPT+  +S      AP  S+ 
Sbjct: 1860 TSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSML 1919

Query: 1952 -----------TSA-------PTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTS 1993
                       TSA       P    T+ P+  +  A +     A   +TT+   TSTT 
Sbjct: 1920 VLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTC 1979

Query: 1994 AP 1995
             P
Sbjct: 1980 VP 1981


>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score =  612 bits (1577), Expect = e-174
 Identities = 381/1126 (33%), Positives = 548/1126 (48%), Gaps = 65/1126 (5%)

Query: 80   VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQE--SAAPTLSRV- 136
            +C  WG  H +TFDG  +   G  +Y          + F+IQ+    +  S+  T SR  
Sbjct: 150  ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 209

Query: 137  -LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSL 195
             L  V    I L K  V   G  V LP       +QQ + Y  V  +    L W+   ++
Sbjct: 210  SLFFVGEQEIHLAK-EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAV 268

Query: 196  LLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL---QKMDDPTEQCQD 250
             +++  +    T GLCG+ N  P   +L++ + KLT   +EF +    Q  + P      
Sbjct: 269  YIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327

Query: 251  PVPEPP---RNCSTGFGI---CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304
             +P PP   +N  T  G+   CE LL    F  C A V    +  +C  DLC  +    +
Sbjct: 328  SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLC--QSMGDV 384

Query: 305  SCVCHTLAEYSRQCTHAGGLPQDWRGP-DFCPQKCPNN-MQYHECRSPCADTCSNQEHSR 362
            +  C  LAEY+R C  AG   Q WR     C   C      Y+EC + C  +C  +    
Sbjct: 385  ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCV 444

Query: 363  ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGR 422
              E  CV GC+CP G + +D    GCV  ++C C ++G  Y PG+    DC  CTC+ G+
Sbjct: 445  DSEIACVDGCYCPNGLIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGK 501

Query: 423  WSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD 482
            W C    CP  CSV G  HF+TFDG++YT    C Y+L K   S  FTV  +   CGL  
Sbjct: 502  WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQ 561

Query: 483  SETCLKSVTLSL-DGVQTVVVIKASGEVFLNQIYTQLPISAANV-TIFRPSTFFIIAQTS 540
               C++SV++ L    +  V +  +G+V L   Y  +P    +   I R S+ F+  +T+
Sbjct: 562  DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 621

Query: 541  LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600
            +G+++ L     ++L++Q+  +    T GLCG FN    DDF +  GV E+T   F N++
Sbjct: 622  VGVRV-LYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSW 680

Query: 601  KTQAAC-PNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMF 659
            KT +AC P +  S  DPC + ++   Y+   CS LT     F  C A + P  Y+  C  
Sbjct: 681  KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRR 738

Query: 660  DTCNCERSEDCLCAALSSYVHACAAKGVQLG-GWRDGVCTKPMTTCPKSMTYHYHVSTCQ 718
            D C C   + CLCA L+ Y H C   G+ +    R   C     +C  S  Y   V+ C 
Sbjct: 739  DACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACA---LSCEASKEYSPCVAPCG 793

Query: 719  PTCRSLSEGDITCSVGFIP-------VDGCICPKGTFLDDTGK-CVQASNCPCYHRGSMI 770
             TC+ L+  +  C V           V+GC CP  T+LD     CV  + C C+ +G   
Sbjct: 794  RTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 852

Query: 771  PNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPG---DTGAGCQKSC 827
            P G+S   S   C C  G +SC   +APA  C A  VF +C +            C++  
Sbjct: 853  PPGDSDIPSLGHCHCKDGVMSC-DSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQL 911

Query: 828  HTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTC 887
              L ++   P C+ GC CP GL+  G+  C   E+CPC      Y  G  +   C+TC C
Sbjct: 912  LNLSVSARGP-CLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVC 969

Query: 888  DSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVV 947
                ++CT  PC +TC  YGD HY TFDG  + F G C+  LV      K ++  SF V+
Sbjct: 970  QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVI 1023

Query: 948  TENVPCGTTGTTCSKAIKIFLGG----FELKLSHGKVEVIGTDESQEVPYTIRQMGIYLV 1003
             ENV C ++G  C K I I +G     F+    +   E    D+ QEV +T R     LV
Sbjct: 1024 VENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESF-LDDKQEV-HTWRVGFFTLV 1081

Query: 1004 VDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGN 1063
                  + LLWD++T++ +   P+++G++ GLCGNFD   +N+  T     + +  EFG+
Sbjct: 1082 HFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGS 1141

Query: 1064 SWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDA 1123
            SW  +  CPD L P+D C  NP R+ +A+K+CSIL    F  CH  V+   +Y  C+ D 
Sbjct: 1142 SWA-AVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1200

Query: 1124 CACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYN 1169
            C C  GGDCECFC +V+AYA  C + G+ V WRTP +CP  CD++N
Sbjct: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1246



 Score =  231 bits (590), Expect = 4e-60
 Identities = 152/486 (31%), Positives = 221/486 (45%), Gaps = 62/486 (12%)

Query: 821  AGCQKSCHTLDMTCYSPQ--CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTI 878
            A C  SCH    +C   +  CV GC CP+GL+ + +GGC+   +CPC  +   Y  G  +
Sbjct: 431  ACCPASCHPR-ASCVDSEIACVDGCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVV 488

Query: 879  RVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKD 938
            +  CNTCTC S  W C+   C A C+V GD H+ TFDG+ Y+F   C+Y L ++   G  
Sbjct: 489  KEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG-- 546

Query: 939  STQDSFRVVTENVPCGTTGT-TCSKAIKIFL------------GGFELKLSHGKVEVIGT 985
                +F V  +N PCG      C +++ + L             G  L     K+    T
Sbjct: 547  ----TFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYT 602

Query: 986  DESQEVPYTIRQMGIYLVVDTDIGLVLLWDKK-TSIFINLSPEFKGRVCGLCGNFDDIAV 1044
            D++ E+    R   ++L V T++G+ +L+D++   +++ +   +     GLCG F+    
Sbjct: 603  DDAFEIR---RLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQ 659

Query: 1045 NDFATRSRSVVGDVLEFGNSWKLSPSCPDALA--PKDPCTANPFRKSWAQKQCSILHGPT 1102
            +DF +           FGNSWK   +C   ++  P DPC  +    S++ + CS+L G  
Sbjct: 660  DDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM 719

Query: 1103 FAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTP-SIC 1161
            FA C A + P  Y+E C  DAC C       C C  +A YA  C   GL V +R     C
Sbjct: 720  FAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPAC 775

Query: 1162 PLFCDYYNPEGQCEWHYQPCGVPCLRTCRN---------PRGDCLRDVWGLEGCYPKCPP 1212
             L C+           Y PC  PC RTC++           GD L     +EGC   CPP
Sbjct: 776  ALSCE-------ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPP 826

Query: 1213 EAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPG-AVVPSDKNCQSCLCTERGVECTYK 1271
            +    D     CV     P     CH  G  Y PG + +PS  +C    C +  + C  +
Sbjct: 827  DT-YLDTQADLCV-----PRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSR 877

Query: 1272 AEACVC 1277
            A A  C
Sbjct: 878  APAAAC 883



 Score =  184 bits (468), Expect = 6e-46
 Identities = 136/449 (30%), Positives = 201/449 (44%), Gaps = 68/449 (15%)

Query: 887  CDSRMWRCTDDPCL----------ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGG 936
            CD R +  T   C           + C  +G  H  TFDG  Y  +G   YTLV  H   
Sbjct: 125  CDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRH--- 181

Query: 937  KDSTQDSFRVVTENVP-CGTTGTTCSKAIKIFLGGFE-----LKLSHGKVEVIGTDESQE 990
             +    SF +   N P CG++  TCS+A+ +F  G +      +++HG + V       +
Sbjct: 182  -EPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRV-------Q 233

Query: 991  VPYT-----IRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVN 1045
            +P+      ++Q+  Y++V       L WD  ++++I +SPE  G   GLCGN +    +
Sbjct: 234  LPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 293

Query: 1046 DFATRSRSVVGDVLEFGNSWKLS-----PSCPDALAPKDPCTA-NPFRKSWAQKQCSILH 1099
            D  T S  +  DV+EF +SW+       P    +  P+ PC   NP       +QC  L 
Sbjct: 294  DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL 353

Query: 1100 GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTP 1158
             P F ACHA+V P  +  +C +D C   S GD   +C A+A YA+AC + G  +  WRT 
Sbjct: 354  RPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 411

Query: 1159 -SICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCL-RDVWGLEGCYPKCPPEAPI 1216
               C + C       +  + Y  C   C  +C +PR  C+  ++  ++GCY  CP    I
Sbjct: 412  LRQCTVHCK------EKAFTYNECIACCPASC-HPRASCVDSEIACVDGCY--CP-NGLI 461

Query: 1217 FDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACV 1276
            F++      A CP       C  HG  Y PG+VV  D  C +C CT    EC+       
Sbjct: 462  FEDGGCVAPAECP-------CEFHGTLYPPGSVVKED--CNTCTCTSGKWECSTAVCPAE 512

Query: 1277 CTYNGQRFHPGDVIYHTTDGTGGCISARC 1305
            C+        GD+ + T DG      A C
Sbjct: 513  CSVT------GDIHFTTFDGRRYTFPATC 535



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 69/285 (24%), Positives = 110/285 (38%), Gaps = 18/285 (6%)

Query: 143  VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELDTK 202
            V I      V V+  PV  P S+ G  I+ +     +     + + W H   L++   +K
Sbjct: 2179 VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASK 2238

Query: 203  YAN-KTCGLCGDFNGMPVVSELLSHNTKL----TPMEFGNLQKMDDPTEQCQDPVPEPPR 257
             +  +  GLCG  +G       L   + +     P  F +  ++             P  
Sbjct: 2239 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298

Query: 258  NCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQ 317
              +T    C  ++  + FS C   V   S+ E       +  DT  +   C  L  Y   
Sbjct: 2299 CATTDCSPCLRMVSNRTFSACHRFVPPESFCEL------WIRDTKYVQQPCVALTVYVAM 2352

Query: 318  CTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD--TCSNQEHSRACEDHCVA---GC 372
            C H   +  +WR  D+CP  C ++  Y  C + C    TC +        +HC     GC
Sbjct: 2353 C-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2411

Query: 373  FCPEGTVLDDIGQTGCVPVSKCACVYN-GAAYAPGATYSTDCTNC 416
             C EGT+L       C+P +KCAC  + G   A G T+++  + C
Sbjct: 2412 VCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2456



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 79/334 (23%), Positives = 126/334 (37%), Gaps = 48/334 (14%)

Query: 875  GQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHC 934
            G  +RVG + C     +W C        C+++ D  ++TFDG   +   +  Y L Q+  
Sbjct: 2091 GLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSP- 2141

Query: 935  GGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGKVEVIGTDESQEV--- 991
              +  T       + N+        C   + +     ++ +     +V  T + Q V   
Sbjct: 2142 -DEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKV--TVDLQPVWPP 2198

Query: 992  ----PYTIRQMGIYLVVDTDIGLVLLWDKKTSIFI-NLSPEFKGRVCGLCGNFDDIAVND 1046
                 + I   G   ++ T   + + W   + + I   S   K +  GLCG  D  A ND
Sbjct: 2199 VSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAAND 2258

Query: 1047 FATRSRSVVG---DVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCS----ILH 1099
               +  SVVG   D   F +SW++    P +L         P   S A   CS    ++ 
Sbjct: 2259 LTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQTRFRP--DSCATTDCSPCLRMVS 2312

Query: 1100 GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPS 1159
              TF+ACH  V P  + E  + D             C A+  Y   CH+  +C+ WR   
Sbjct: 2313 NRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSD 2366

Query: 1160 ICPLFCDYYNPEGQCEWHYQPCGVPC--LRTCRN 1191
             CP  C         +  YQ C   C   +TC++
Sbjct: 2367 YCPFLC-------SSDSTYQACVTACEPPKTCQD 2393



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 148/661 (22%), Positives = 225/661 (34%), Gaps = 108/661 (16%)

Query: 386  TGCVPVSKCACV-----------YNGAAYAPGATYSTDCTNCTCS---GGRWSCQEVPCP 431
            T CVP+++  CV            N + + P       C     +   GG   C    C 
Sbjct: 2049 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECA 2108

Query: 432  GTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD---SETCLK 488
              CS+     F TFDG    +  +  Y+L++  D      + + +   L        CL 
Sbjct: 2109 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2168

Query: 489  SVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQ 548
             + ++    Q V + + + +V ++      P+S     I      ++I   S    + +Q
Sbjct: 2169 MLNMTHLAHQ-VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQ 2224

Query: 549  LVPTMQLFMQLAPKL-RGQTCGLCGNFNSIQADDFRTLSGVVEATA---AAFFNTFKTQA 604
             + +  L +  A K  + Q  GLCG  +   A+D     G V   A   A F ++++  +
Sbjct: 2225 WLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPS 2284

Query: 605  ACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNC 664
            +  ++  +   P S +  +        S  T     F  CH  V P ++    + DT   
Sbjct: 2285 SLTSVGQTRFRPDSCATTDCSPCLRMVSNRT-----FSACHRFVPPESFCELWIRDTKYV 2339

Query: 665  ERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQP--TCR 722
            ++     C AL+ YV  C    V +   R   C      C    TY   V+ C+P  TC+
Sbjct: 2340 QQP----CVALTVYVAMCHKFHVCIEWRRSDYCP---FLCSSDSTYQACVTACEPPKTCQ 2392

Query: 723  SLSEGDITCSVGFIPVDGCICPKGTFLD--DTGKCVQASNCPCY-HRGSMIPNGESVHDS 779
                G +      +  +GC+C +GT L    +  C+  + C C    G     GE+ + S
Sbjct: 2393 DGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSS 2452

Query: 780  GAICTCTHGKLSCIGGQAPAPV---CAAPM---------VFFDCRNATPGDTGAGC---Q 824
             + C C H    C       PV   C +P          V        P   G  C   Q
Sbjct: 2453 LSGC-CQH---QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQ 2508

Query: 825  KSCHTLDMTC------------------YSPQC---------VPGCVCPDGLVADGEG-G 856
              C  L  TC                  YS +C         VP C     L+    G  
Sbjct: 2509 TLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDS 2568

Query: 857  CITA-----EDCP-----CVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPC---LATC 903
            C T+      DCP     C   EA      T  + C    C    +RC    C    A  
Sbjct: 2569 CCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALV 2628

Query: 904  AVYGDGHYLTFDGQSYSFNGDCEYTLVQN-HCGGKDSTQDSFRVVTENVPCGTTGTTCSK 962
             V+       +     S   DC+   V   H   K    + F    ENV CG     C K
Sbjct: 2629 EVWSPDRCCPYK----SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENV-CGCAKYECVK 2683

Query: 963  A 963
            A
Sbjct: 2684 A 2684



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 104/450 (23%), Positives = 147/450 (32%), Gaps = 73/450 (16%)

Query: 1174 CEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCV--ATCPTP 1231
            CEW Y  C  PC +TCR+PR    RDV     C P C P   + DE   +CV    C  P
Sbjct: 1408 CEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVC-PTPQVLDEVTQRCVYLEDCVEP 1466

Query: 1232 PLPPRCHVHGKSYRP---GAVVPSDKNCQ------------------SCLCTERGVECTY 1270
             +       G    P   G   PSD+  Q                  + L T      T 
Sbjct: 1467 AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTA 1526

Query: 1271 KAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFS 1330
              E  V     Q      +    +    G   +      T      P +P +   P    
Sbjct: 1527 TEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQ 1586

Query: 1331 FSTPPLVVSSTHTP--------SNGPSSAHTGPPSSAWP------TTAG-------TSPR 1369
              TP +V  +  T         S   + +   PP+  +P      T  G       T+P 
Sbjct: 1587 TPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPP 1646

Query: 1370 TRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCES---PRS 1426
                TAS S  PV       SP      P   T SG    +  L     +V      P+ 
Sbjct: 1647 QPSLTASPSSRPVA------SPGAISRSP---TSSGSHKAV--LTPAVTKVISRTGVPQP 1695

Query: 1427 VECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLA--CSTS 1484
             + ++  +P  PL   G   +  P   L  R+ E             Q   P+    S  
Sbjct: 1696 TQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQ---PMGSPASPQ 1752

Query: 1485 SSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTA----RTTPAPGTATSVKKTFSTP 1540
              P  + PP  ++ T       + P  TP   SLSTA      TP     ++      + 
Sbjct: 1753 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1812

Query: 1541 SPP----PVPATSTSS-MSTTTPGTSVVSS 1565
             PP    P+    TS+ ++T  P  SV+++
Sbjct: 1813 LPPDTSLPLAKVGTSAPVATPGPKASVITT 1842



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 51/186 (27%), Positives = 71/186 (38%), Gaps = 33/186 (17%)

Query: 1848 PVTST--PVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYA------H 1899
            PVT+T  PV +P         PTQ+T       T + +    T +P +    A      H
Sbjct: 1523 PVTATEEPVVSPG--------PTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1574

Query: 1900 TTSTTSAPTARTTSAP--------TTRTT---SASPASTTSGPGNTPSPVPTTSTISAPT 1948
            T  ++S P A  T  P        TTR T   + SP  T S   + P+P     T +   
Sbjct: 1575 TPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSS-RSPPAPRFPLMTKAVTV 1633

Query: 1949 TSITSAPTTSTTSAP--TSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTT 2006
                S P  +T   P  T+S +S P  S  +   S T+S    +  +   T   S  G  
Sbjct: 1634 RGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV- 1692

Query: 2007 PSPVPT 2012
              P PT
Sbjct: 1693 --PQPT 1696



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 73/344 (21%), Positives = 117/344 (34%), Gaps = 47/344 (13%)

Query: 1687 VATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPT------ATSVTQGTHTTPVT 1740
            VA   PTP       +TT  T +  A +   T +SR  P         +VT   H +   
Sbjct: 1583 VALQTPTPGMVSGAMETTRVTVI-FAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPV 1641

Query: 1741 RNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRL---------- 1790
            R   P+ + T       PS  P         +   SG         +T++          
Sbjct: 1642 RTTPPQPSLTA-----SPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPT 1696

Query: 1791 QCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVT 1850
            Q ++ S P   +   G   +      L  R+       ++ L+ E        P G P +
Sbjct: 1697 QAQSASSPSTPLTVAGTAAEQVPVSPLATRS------LEIVLSTEKGEAGHSQPMGSPAS 1750

Query: 1851 STPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTAR 1910
              P   PS P              + ++ TT+ T S    P+T    + +T+T       
Sbjct: 1751 PQPHPLPSAPP-------------RPAQHTTMATRSPALPPETPAAASLSTATDGLAATP 1797

Query: 1911 TTSAPTTRTTSASPASTTSG-PGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTS 1969
              S  +TR     P+   SG P +T  P+    T +   T    A   +T   P ++T  
Sbjct: 1798 FMSLESTR-----PSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLP 1852

Query: 1970 APTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
            A T S     T +  +     T  AP  + T+      + +PT+
Sbjct: 1853 AQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTS 1896



 Score = 39.3 bits (90), Expect = 0.039
 Identities = 47/167 (28%), Positives = 64/167 (38%), Gaps = 21/167 (12%)

Query: 1850 TSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTA 1909
            TS PV  P   +    +P Q  ++   ++T + V   T +    + T AH  +  + P A
Sbjct: 1826 TSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPA----AMTQAHPPTHIAPPAA 1881

Query: 1910 RTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTS--APTSST 1967
             T  AP     +  P S     G  P    T S +S         P  STT   A  S  
Sbjct: 1882 GT--APGLLLGATLPTS-----GVLPVAEGTASMVSV-------VPRKSTTGKVAILSKQ 1927

Query: 1968 TSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSG-PGTTPSPVPTT 2013
             S PT+   SA    T  +P TS    P  +   G    T  PVPT+
Sbjct: 1928 VSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTS 1974



 Score = 35.8 bits (81), Expect = 0.44
 Identities = 40/185 (21%), Positives = 60/185 (32%), Gaps = 35/185 (18%)

Query: 1855 TAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST-----TSAPTA 1909
            T P +      S  +   S +  RT T     T + P T+      T+T     +  PT 
Sbjct: 1479 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQ 1538

Query: 1910 RTTSAPTTRTTSASPASTTSGPG------------NTPSPVPTTSTISAPTTSITSAPTT 1957
             T   P   T S  PA  T  P             +TP        +  PT  + S    
Sbjct: 1539 TTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAME 1598

Query: 1958 STTSAPTSSTTSAPTTSTTSAPTSS------------------TTSSPQTSTTSAPTTST 1999
            +T      + +   T S+ S P                      T+ PQ S T++P++  
Sbjct: 1599 TTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRP 1658

Query: 2000 TSGPG 2004
             + PG
Sbjct: 1659 VASPG 1663



 Score = 35.8 bits (81), Expect = 0.44
 Identities = 33/129 (25%), Positives = 42/129 (32%), Gaps = 16/129 (12%)

Query: 1885 TSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTI 1944
            T +   PQ S     T      PT R    P    T+A     T+      SP PT +T+
Sbjct: 1488 TPSDEEPQLSQESPRT------PTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTL 1541

Query: 1945 SAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPG 2004
              P     S      T +P S   +A   +    P SS          S P    T  PG
Sbjct: 1542 QQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESS----------SLPVALQTPTPG 1591

Query: 2005 TTPSPVPTT 2013
                 + TT
Sbjct: 1592 MVSGAMETT 1600



 Score = 32.7 bits (73), Expect = 3.7
 Identities = 31/104 (29%), Positives = 45/104 (43%), Gaps = 16/104 (15%)

Query: 1477 TPLACSTSSSPAQTT---PPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSV 1533
            TP     S+ P+Q     PP TS        G+SAP +TPG  +  +  TTP    AT++
Sbjct: 1796 TPFMSLESTRPSQLLSGLPPDTS--LPLAKVGTSAPVATPGPKA--SVITTPLQPQATTL 1851

Query: 1534 KKTFSTPSPPPVPATSTSS---------MSTTTPGTSVVSSKPT 1568
                 +P  P  PA  T +          + T PG  + ++ PT
Sbjct: 1852 PAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPT 1895



 Score = 31.6 bits (70), Expect = 8.2
 Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 13/68 (19%)

Query: 327  DWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQT 386
            +WR  D C   C     +  CR P A +C +    R+C         CP   VLD++ Q 
Sbjct: 1409 EWRY-DACASPC-----FQTCRDPRAASCRDVPRGRSCVP------VCPTPQVLDEVTQR 1456

Query: 387  GCVPVSKC 394
             CV +  C
Sbjct: 1457 -CVYLEDC 1463



 Score = 31.6 bits (70), Expect = 8.2
 Identities = 46/182 (25%), Positives = 60/182 (32%), Gaps = 34/182 (18%)

Query: 1848 PVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAP 1907
            P T     A  T  G  +  T  TS        T    S      T+   A  +   S P
Sbjct: 1872 PPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLP 1931

Query: 1908 TARTTSA---PTTRTTSASP------ASTTSGPGNTPSPVPTTSTIS------APTTSI- 1951
            T+   SA   PT  T + S       A        T  PVPT+  +S      AP  S+ 
Sbjct: 1932 TSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSML 1991

Query: 1952 -----------TSA-------PTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTS 1993
                       TSA       P    T+ P+  +  A +     A   +TT+   TSTT 
Sbjct: 1992 VLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTC 2051

Query: 1994 AP 1995
             P
Sbjct: 2052 VP 2053


>gi|134031945 SCO-spondin [Homo sapiens]
          Length = 5147

 Score =  602 bits (1553), Expect = e-172
 Identities = 416/1290 (32%), Positives = 579/1290 (44%), Gaps = 131/1290 (10%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPT-LSRVLMK 139
            C++W  FHY+TFDG  + F G C Y+ +   GAA   + + L        P    RV M 
Sbjct: 195  CASWSGFHYRTFDGRHYHFLGRCTYLLA---GAADSTWAVHLTPGDRCPQPGHCQRVTMG 251

Query: 140  VDGVVIQLTKGSVLVNGHPVLLPFSQS----GVLIQQSSSYTKVEARLGLVLMWNHDDSL 195
             + V+IQ   G+V V G   L+P  QS    G+ +Q    +  +   LG+V+  +   S+
Sbjct: 252  PEEVLIQA--GNVSVKGQ--LVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSI 307

Query: 196  LLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME--FGNLQKMDDPTEQCQDPVP 253
             + +D +   +T GLCG +NG P   + +     L  +   FGN  ++      C D V 
Sbjct: 308  SISVDHELWGQTQGLCGLYNGWPE-DDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVE 366

Query: 254  ---------------EPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCF- 297
                           EP    +    +C +LL G  F  C A V    Y EAC    C  
Sbjct: 367  VAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGP-FGQCHAQVSPAEYHEACLFAYCAG 425

Query: 298  ----CEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD 353
                         VC T A Y + C     +   WR P FC + CP    Y +C S C  
Sbjct: 426  AMAGSGQEGRQQAVCATFASYVQACARRH-IHIRWRKPGFCERLCPGGQLYSDCVSLCPP 484

Query: 354  TCS--NQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYST 411
            +C    Q    +C + CV+GC CP G   +    T CVP + C C Y    Y PG T   
Sbjct: 485  SCEAVGQGEEESCREECVSGCECPRGLFWNG---TLCVPAAHCPCYYCRQRYVPGDTVRQ 541

Query: 412  DCTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGD--CSYVLTKPCDSSAF 469
             C  C C  GRW C +  CP  C+V G  H+ TFDG+ Y+  G   C Y L +       
Sbjct: 542  LCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQL 601

Query: 470  TVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLP-ISAANVTIF 528
             +L E   C   D+ +CL ++++SL+   T + ++ SG V +N     LP I A  +++ 
Sbjct: 602  LILLEHGAC---DAGSCLHAISVSLE--DTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVR 656

Query: 529  RPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGV 588
            R S+ F++ +   G Q+   L   +  ++ L P+   Q  GLCG F   Q DDF T +G 
Sbjct: 657  RASSAFLLLRWP-GAQVLWGLSDPVA-YITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGD 714

Query: 589  VEATAAAFFNTFKT--QAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHA 646
            VE + AAF + F+   +  CP+  ++   PC+   +   +A+  C+ L  +   F  CH 
Sbjct: 715  VETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSS--VFQECHR 772

Query: 647  AVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPK 706
             V    +Y  C+   C C+   DCLC  LS+Y   CA +G     WR+      M  CP 
Sbjct: 773  LVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVM--CPG 829

Query: 707  SMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHR 766
               Y      C P C         C      V GC CP G   D  G+CV  S CPC   
Sbjct: 830  GQEYR----ECAPACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLG 885

Query: 767  GSMIPNGESVHDSGAICTCTH-GKLSCIGGQAPAPV-CAAPMVFFDCRNATPGDTGAGCQ 824
                  G +       C C   G  +C     P+   C   +V+       PG     C 
Sbjct: 886  ARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVY------APG----ACL 935

Query: 825  KSCHTLDMTCYSPQ-CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCN 883
             +C +       P     GCVCP G V   E  C+  + CPC H+   Y    TI+  CN
Sbjct: 936  LTCDSPSANHSCPAGSTDGCVCPPGTVLLDER-CVPPDLCPCRHSGQWYLPNATIQEDCN 994

Query: 884  TCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDS 943
             C C  R W CT       C   G  HY+TFDG ++++ G CEY LV+   G        
Sbjct: 995  VCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASG-------L 1047

Query: 944  FRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGK-VEVIGTDESQEVPYT-----IRQ 997
            F V  +N+PCG +G TC+KA+ + L G  + +  G+ V V G   +    YT     +R+
Sbjct: 1048 FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRR 1107

Query: 998  MGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGD 1057
             G++L++ T +GL LLWD  T + + LSP+F+GRV GLCG+FD  A ND  +R   +   
Sbjct: 1108 AGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPT 1167

Query: 1058 VLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYE 1117
                 +SW+LSP CP+      PCT N  R  WA+ +C  L  P F  CHA V P ++YE
Sbjct: 1168 AELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYE 1227

Query: 1118 ACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWH 1177
             C+ DAC CDSGGDCEC C+A+A YA  C   G  V WR+  +C L C+     GQ    
Sbjct: 1228 WCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCE----GGQV--- 1280

Query: 1178 YQPCGVPCLRTCR----NPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPL 1233
            Y+ CG  C  TC      P   C + V  +EGC+  C PE  +         A+CP    
Sbjct: 1281 YEACGPTCPPTCHEQHPEPGWHC-QVVACVEGCF--C-PEGTLLHGGACLEPASCP---- 1332

Query: 1234 PPRCHVHGKSYRPGAVVPSDKNCQSCLCTE-------RGVECTYKAEAC-----VCTYNG 1281
               C     S+ PG+V+   K+C +C C E        G  C     AC     +C  NG
Sbjct: 1333 ---CEWGRNSFPPGSVL--QKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQENG 1387

Query: 1282 QRFHPGDVIYHTTD-GTG----GCISARCG 1306
                 G +  +  D G G    GC +  CG
Sbjct: 1388 HCVPHGWLCDNQDDCGDGSDEEGCAAPGCG 1417



 Score =  246 bits (629), Expect = 1e-64
 Identities = 180/610 (29%), Positives = 256/610 (41%), Gaps = 64/610 (10%)

Query: 334  CPQK--CPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPV 391
            CP +  CP  + Y      C  TC +   + +C      GC CP GTVL D     CVP 
Sbjct: 917  CPSQAFCPRELVY--APGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLD---ERCVPP 971

Query: 392  SKCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYT 451
              C C ++G  Y P AT   DC  C C G +W C      G C   G  H+ TFDG  +T
Sbjct: 972  DLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFT 1031

Query: 452  VHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFL 511
              G C Y+L +   S  FTV A+   CG +   TC K++ + L+G  TVV +     V +
Sbjct: 1032 YPGACEYLLVREA-SGLFTVSAQNLPCGASGL-TCTKALAVRLEG--TVVHMLRGRAVTV 1087

Query: 512  NQIYTQLP-ISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGL 570
            N +    P +        R +  F++  T LGL L        ++ +QL+P+ RG+  GL
Sbjct: 1088 NGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWD--GGTRVLVQLSPQFRGRVAGL 1145

Query: 571  CGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQHW 630
            CG+F+   ++D R+  GV+E TA    ++++    CP        PC+++     +A+  
Sbjct: 1146 CGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPE-PGDLPHPCTMNTHRAGWARAR 1204

Query: 631  CSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDC--LCAALSSYVHACAAKGVQ 688
            C  L      F  CHA V P  +Y  C++D C C+   DC  LC+A+++Y   CA  G  
Sbjct: 1205 CGALLQP--LFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHH 1262

Query: 689  LGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLS-EGDITCSVGFIPVDGCICPKGT 747
            +      +C+     C     Y     TC PTC     E    C V    V+GC CP+GT
Sbjct: 1263 VRWRSQELCS---LQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQV-VACVEGCFCPEGT 1318

Query: 748  FLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIGG----QAPAPVCA 803
             L   G C++ ++CPC    +  P G  +      CTC  G+  C G     +   P CA
Sbjct: 1319 LLHG-GACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACA 1377

Query: 804  APMVFFD-----------CRNATPGDTGA---GCQK-SCHTLDMTCYSPQCVPGCV---- 844
                              C N      G+   GC    C    MTC S  C+P  +    
Sbjct: 1378 EGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDR 1437

Query: 845  --------------CPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSR 890
                          CP GL+A  +G C+        H +    A +   +G    TC   
Sbjct: 1438 QDDCGDGTDEPSYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEESCLG--QVTCVPG 1495

Query: 891  MWRCTDDPCL 900
               C D  CL
Sbjct: 1496 EVSCVDGTCL 1505



 Score =  149 bits (375), Expect = 4e-35
 Identities = 123/428 (28%), Positives = 184/428 (42%), Gaps = 37/428 (8%)

Query: 392 SKCACVYNGAAYAPGATYSTDCTNCTCS--GGRWSCQEVPCPGTCSVLGGAHFSTFDGKQ 449
           S  AC    + + PG+  S           G  WS  + P   TC+   G H+ TFDG+ 
Sbjct: 152 SSQACRSCSSRHLPGSASSPALLQPLAGAVGQLWSQHQRPS-ATCASWSGFHYRTFDGRH 210

Query: 450 YTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEV 509
           Y   G C+Y+L    DS+    L    RC         + VT+  +     V+I+A    
Sbjct: 211 YHFLGRCTYLLAGAADSTWAVHLTPGDRC---PQPGHCQRVTMGPE----EVLIQAGNVS 263

Query: 510 FLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCG 569
              Q+  +      +    +    +++    LG+ + L    T  + + +  +L GQT G
Sbjct: 264 VKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLD--RTGSISISVDHELWGQTQG 321

Query: 570 LCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFE-----DPCSL---SV 621
           LCG +N    DDF    G +   AA F N+++   +     ++ E     DP  L    V
Sbjct: 322 LCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPLGLIDADV 381

Query: 622 EN---EKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTC-------NCERSEDCL 671
           E       AQ  C QL   +GPFG+CHA V P  Y+  C+F  C         E  +  +
Sbjct: 382 EPGHLRAEAQDVCHQL--LEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAV 439

Query: 672 CAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITC 731
           CA  +SYV ACA + + +   + G C +    CP    Y   VS C P+C ++ +G+   
Sbjct: 440 CATFASYVQACARRHIHIRWRKPGFCER---LCPGGQLYSDCVSLCPPSCEAVGQGEEE- 495

Query: 732 SVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLS 791
           S     V GC CP+G F + T  CV A++CPCY+       G++V      C C  G+  
Sbjct: 496 SCREECVSGCECPRGLFWNGT-LCVPAAHCPCYYCRQRYVPGDTVRQLCNPCVCRDGRWH 554

Query: 792 CIGGQAPA 799
           C     PA
Sbjct: 555 CAQALCPA 562



 Score =  124 bits (310), Expect = 1e-27
 Identities = 124/427 (29%), Positives = 172/427 (40%), Gaps = 73/427 (17%)

Query: 901  ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTC 960
            ATCA +   HY TFDG+ Y F G C Y L     G  DST      +T    C   G   
Sbjct: 193  ATCASWSGFHYRTFDGRHYHFLGRCTYLL----AGAADSTWAVH--LTPGDRCPQPG--- 243

Query: 961  SKAIKIFLGGFELKLSHGKVEVIGTDESQEVP---------YTIRQMGIYLVVDTDIGLV 1011
                ++ +G  E+ +  G V V G    Q VP          +++ +G +LV+   +G+V
Sbjct: 244  -HCQRVTMGPEEVLIQAGNVSVKG----QLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVV 298

Query: 1012 LLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPS- 1070
            +  D+  SI I++  E  G+  GLCG ++    +DF      +      FGNSW+L  S 
Sbjct: 299  VRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSE 358

Query: 1071 --CPDALAPKDPC---------TANPFRKSWAQKQC-SILHGPTFAACHAHVEPARYYEA 1118
              C DA+     C               ++ AQ  C  +L GP F  CHA V PA Y+EA
Sbjct: 359  SGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGP-FGQCHAQVSPAEYHEA 417

Query: 1119 CVNDACA---CDSG--GDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQ 1173
            C+   CA     SG  G  +  C   A+Y QAC    + + WR P  C   C    P GQ
Sbjct: 418  CLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLC----PGGQ 473

Query: 1174 CEWHYQPCGVPCLRTC----RNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCP 1229
                Y  C   C  +C    +     C  +   + GC  +C P    ++       A CP
Sbjct: 474  L---YSDCVSLCPPSCEAVGQGEEESCREEC--VSGC--EC-PRGLFWNGTLCVPAAHCP 525

Query: 1230 TPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYNGQRFHPGDV 1289
                   C+   + Y PG  V   + C  C+C +    C        C         GD 
Sbjct: 526  -------CYYCRQRYVPGDTV--RQLCNPCVCRDGRWHCAQALCPAECAVG------GDG 570

Query: 1290 IYHTTDG 1296
             Y T DG
Sbjct: 571  HYLTFDG 577



 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 37/101 (36%), Positives = 52/101 (51%), Gaps = 6/101 (5%)

Query: 334  CPQKCPNNMQYHECRSPCADTCSNQEHSRACEDH--CVAGCFCPEGTVLDDIGQTGCVPV 391
            C   CP  M+   C + C   CS+ +    C+D   C  GC CP+G++  D    GCVP+
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQD---GGCVPI 4114

Query: 392  SKCACV-YNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCP 431
              C C    G ++APG+ +   C NC+C  G+ SC   PCP
Sbjct: 4115 GHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCP 4155



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 40/108 (37%), Positives = 48/108 (44%), Gaps = 10/108 (9%)

Query: 334  CPQKCPNNM------QYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTG 387
            C  +CP NM      Q H+   PC   C  Q     C   C  GC CP G  L +     
Sbjct: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHN---AS 2938

Query: 388  CVPVSKCACVYNGAAYAPGATYSTD-CTNCTCSGGRWSCQEVPCPGTC 434
            C+P S+C C  +G  YA GA    D C NCTC  G+ +C    CP  C
Sbjct: 2939 CLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVAC 2986



 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 32/86 (37%), Positives = 46/86 (53%), Gaps = 4/86 (4%)

Query: 350  PCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
            PC  +C + + +R+C  HCV GC CP G +L D   T C+P+S+C C+       PG ++
Sbjct: 2634 PCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHD---TRCLPLSECPCLVGEELKWPGVSF 2690

Query: 410  ST-DCTNCTCSGGRWSCQEVPCPGTC 434
               +C+ C C  G   CQ   CP  C
Sbjct: 2691 LLGNCSQCVCEKGELLCQPGGCPLPC 2716



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 46/169 (27%), Positives = 65/169 (38%), Gaps = 24/169 (14%)

Query: 285  GSYLEACRQDLCFCEDTDLLSCVCHTLAE--YSRQ------------CTHAGGLPQDWRG 330
            G Y   C ++  +   +    C C  L +  Y  Q            CT   G  +    
Sbjct: 4356 GCYSGPCPEECVWSSWSSWTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLI 4415

Query: 331  PDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACED--HCVAGCFCPEGTVLDDIGQTGC 388
             +     C    ++H C SPCA  C+     + C+D   C  GC+CP+G +L+  G  GC
Sbjct: 4416 SNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKG-LLEQAG--GC 4472

Query: 389  VPVSKCACVYNGAA-----YAPGATYSTDCTNCTCSGGRWSCQEVPCPG 432
            +P  +C C +  AA      APG      C  C C  G   C    C G
Sbjct: 4473 IPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQG 4521



 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 56/223 (25%), Positives = 77/223 (34%), Gaps = 27/223 (12%)

Query: 699  KPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQA 758
            +P   CP         ++C   C  L  G I       P  GC CP G  L + G CV  
Sbjct: 4813 QPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQP--GCGCPGGQLLHN-GTCVPP 4869

Query: 759  SNCPCYH-------------RGSMIPNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAP 805
            + CPC               +   +P G  +  +   C C  G  SC       P     
Sbjct: 4870 TACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGET- 4928

Query: 806  MVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQC----VPGCVCPDGLVADGEGGCITAE 861
                  +   PG+ G  C+++C  ++ T     C      GCVC  G      G C+  +
Sbjct: 4929 -----WQQVAPGELGL-CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPED 4982

Query: 862  DCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCA 904
             C C H    +  G   +  C +C C S    CT      TCA
Sbjct: 4983 HCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCA 5025



 Score = 68.2 bits (165), Expect = 8e-11
 Identities = 55/198 (27%), Positives = 75/198 (37%), Gaps = 38/198 (19%)

Query: 724  LSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQAS-----NCPCY--------HRGSMI 770
            +++ D TC+  F+ +D   C  G   ++   CV +S      C C         H+G   
Sbjct: 4338 MAKADPTCNSTFLHLDTQGCYSGPCPEE---CVWSSWSSWTRCSCRVLVQQRYRHQGPAS 4394

Query: 771  PNGESVHDSGAICTCTHGKLS-CIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSC-- 827
                +    GA CT   G    C+        C  P  F  C        G+ C   C  
Sbjct: 4395 RGARA----GAPCTRLDGHFRPCLISNCSEDSCTPPFEFHAC--------GSPCAGLCAT 4442

Query: 828  HTLDMTCYS-PQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEA-----SYRAGQTIRVG 881
            H     C   P C PGC CP GL+ +  GGCI  E+C C H  A     +   G  +++G
Sbjct: 4443 HLSHQLCQDLPPCQPGCYCPKGLL-EQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLG 4501

Query: 882  CNTCTCDSRMWRCTDDPC 899
            C  C C      CT   C
Sbjct: 4502 CKECECRRGELHCTSQGC 4519



 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 34/93 (36%), Positives = 46/93 (49%), Gaps = 8/93 (8%)

Query: 343  QYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACV--YNG 400
            +Y  C  PC  +C +  H   C   C  GC+CP G VL   G   CV    C+C+    G
Sbjct: 3318 EYSPCGPPCPRSCDDLVH---CVWRCQPGCYCPPGQVLSSNGAI-CVQPGHCSCLDLLTG 3373

Query: 401  AAYAPGATYSTD--CTNCTCSGGRWSCQEVPCP 431
              + PGA  +    C +CTC  GR +C ++PCP
Sbjct: 3374 QRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP 3406



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 49/157 (31%), Positives = 64/157 (40%), Gaps = 26/157 (16%)

Query: 762  PCYHRGSMIPNGE--SVHDSGAICTCTHGKLSCIGGQAPAP-------VCAAPMVFFDCR 812
            PC  RG+M    +  S  + G  C    G L       P P        C+  ++F  C 
Sbjct: 1765 PC--RGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPC- 1821

Query: 813  NATPGDTGAGCQKSCHTLD--MTCYS--PQCVPGCVCPDGLVADGEGGCITAEDCPCVHN 868
                    A C  +C  +   +TC    P   PGC CP+G V   EG C+    CPC+ +
Sbjct: 1822 --------APCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVD 1873

Query: 869  EASYRAGQTIRVGCNTCTC-DSRMWRCTDDP-CLATC 903
             A Y  GQ I+  C  C C D R  RC  +P C   C
Sbjct: 1874 GARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDC 1910



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 44/134 (32%), Positives = 53/134 (39%), Gaps = 12/134 (8%)

Query: 298  CEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQK-CPN-----NMQYHECRSPC 351
            C  T      CH+     R C    G     R    CPQ  CPN      + +  C +PC
Sbjct: 1766 CRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPC-APC 1824

Query: 352  ADTCSNQEHSRACEDHCVAG---CFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGAT 408
              TC +      C      G   C+CPEG VL   G   CV   +C C+ +GA Y PG  
Sbjct: 1825 PLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGW--CVWPRQCPCLVDGARYWPGQR 1882

Query: 409  YSTDCTNCTCSGGR 422
               DC  C C  GR
Sbjct: 1883 IKADCQLCICQDGR 1896



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 34/97 (35%), Positives = 45/97 (46%), Gaps = 5/97 (5%)

Query: 335  PQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKC 394
            P  CP + Q+ +C    A +C+     R     C  GC CP G +L +     CVP   C
Sbjct: 3087 PGMCPRDKQWLDCAQGPA-SCAELSAPRGTNQTCHPGCHCPSGMLLLN---NVCVPTQDC 3142

Query: 395  ACVYNGAAYAPGATYSTDCTNCTC-SGGRWSCQEVPC 430
             C + G  Y PG+T    C NC+C SG   +C   PC
Sbjct: 3143 PCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPC 3179



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 67/284 (23%), Positives = 90/284 (31%), Gaps = 27/284 (9%)

Query: 629  HWCSQLTDA--DGPFGRCHAAVKPGTYYSNCMFDTCNCE-------RSEDCLCAALSSYV 679
            HWC  +  A  +  F    A   PG +     +  C+         RS  C      +  
Sbjct: 3981 HWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGG 4040

Query: 680  HACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVD 739
              CA +  Q        C      CP  M      + C   C  L EG I C    +   
Sbjct: 4041 APCAGERHQARLCNPMPCE---AGCPAGMEVVTCANRCPRRCSDLQEG-IVCQDDQVCQK 4096

Query: 740  GCICPKGTFLDDTGKCVQASNCPCYH-RGSMIPNGESVHDSGAICTCTHGKLSCIGGQAP 798
            GC CPKG+ L+  G CV   +C C   +G     G    D+   C+C  G+LSC     P
Sbjct: 4097 GCRCPKGS-LEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCP 4155

Query: 799  APVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCI 858
             P   A          +     + C  SC              G   P+      +    
Sbjct: 4156 PPTHCA---------WSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPC 4206

Query: 859  TAEDCP--CVHNEASYRAGQTIRVG-CNTCTCDSRMWRCTDDPC 899
                CP  C+    S   G +   G C  C+C      C D  C
Sbjct: 4207 PQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTEC 4250



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 70/301 (23%), Positives = 98/301 (32%), Gaps = 107/301 (35%)

Query: 702  TTCPKSMTYHYHVSTCQPTCRSLSEGDITC--SVGFIPVDGCICPKGTFLDDTGKCVQAS 759
            T C    + H     C  +C+ LS G +    SVG  P   C CP G    D G CV  +
Sbjct: 3527 TDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPT--CGCPLGQLSQD-GLCVPPA 3583

Query: 760  NCPCYHR--------------GSMIPNGESVHDSGAI------CTCTHGKL--------- 790
            +C C ++              GS   + ES+     +      CTC  G L         
Sbjct: 3584 HCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643

Query: 791  ----------------SCIGGQ-----------APAPV---------------CAAPMVF 808
                            SC GG+            P P                C A  ++
Sbjct: 3644 DPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLY 3703

Query: 809  FDCRNATPGDTGAGCQKSCH--TLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCV 866
             +C+       G GC  SC   T  + C+S  C  GC CP+G        C+  ++CPCV
Sbjct: 3704 RECQ------PGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQH-RLACV--QECPCV 3754

Query: 867  HNEASYR--------------------AGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVY 906
                  +                    +GQT+R  C  C+C      C+ D C      +
Sbjct: 3755 LTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGF 3814

Query: 907  G 907
            G
Sbjct: 3815 G 3815



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 32/111 (28%), Positives = 46/111 (41%), Gaps = 18/111 (16%)

Query: 334  CPQKCPNNMQYHECRSPCADTCSNQEHSRAC-EDHCVAGCFCPEGTVLDDIGQTGCVPVS 392
            CP+ CP       C + C   C + +    C ++ C  GC CP G +L +     CVP +
Sbjct: 4815 CPE-CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHN---GTCVPPT 4870

Query: 393  KCACVYNGAAYA-------------PGATYSTDCTNCTCSGGRWSCQEVPC 430
             C C  +   +              PG   + +CT C C GG +SC  V C
Sbjct: 4871 ACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921



 Score = 58.9 bits (141), Expect = 5e-08
 Identities = 48/187 (25%), Positives = 62/187 (33%), Gaps = 14/187 (7%)

Query: 725  SEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHD---SGA 781
            S GD +C       + C  P        G     S C     G +   G S         
Sbjct: 2806 SPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDT 2865

Query: 782  ICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHT----LDMTCYSP 837
             C   H +      Q     C   M+F           G  C + C T    ++ T +  
Sbjct: 2866 TCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQCH--QEGGPCPRLCLTQGPGIECTGF-- 2921

Query: 838  QCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRV-GCNTCTCDSRMWRCTD 896
             C PGC CP GL       C+    CPC  +   Y +G   R+  CN CTC S    CT 
Sbjct: 2922 -CAPGCTCPPGLFLHN-ASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTS 2979

Query: 897  DPCLATC 903
            + C   C
Sbjct: 2980 ERCPVAC 2986



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 42/141 (29%), Positives = 48/141 (34%), Gaps = 40/141 (28%)

Query: 313  EYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGC 372
            E S QCT  GG                     H C  PC  +C +      C+   V GC
Sbjct: 3521 ENSTQCTDCGG-----------------GQSLHPCGQPCPRSCQDLSPGSVCQPGSV-GC 3562

Query: 373  FCPEGTVLDDIGQTG-CVPVSKCACVYNGAAYA--------------------PGATYST 411
                G  L  + Q G CVP + C C Y   A                      PG   + 
Sbjct: 3563 QPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTG 3622

Query: 412  DCTNCTCSGGRWSCQEVP-CP 431
             C NCTC  G   CQEVP CP
Sbjct: 3623 PCDNCTCVAGILQCQEVPDCP 3643



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 39/117 (33%), Positives = 47/117 (40%), Gaps = 11/117 (9%)

Query: 792  CIGGQAPAPVCAA-PMVFFDC---RNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPD 847
            C G +A   VC A P    +C     A     G  C +SC  L    +  +C PGC CP 
Sbjct: 3291 CEGPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVW--RCQPGCYCPP 3348

Query: 848  GLVADGEGG-CITAEDCPCVHNEASYRAGQTIRV----GCNTCTCDSRMWRCTDDPC 899
            G V    G  C+    C C+      R     R+    GCN CTC      CTD PC
Sbjct: 3349 GQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPC 3405



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 17/122 (13%)

Query: 322  GGLPQDWR------GPDFCPQ-KCPNNMQYHECRSPCADTCSNQEHSRAC-EDHCVAGCF 373
            GG  + W       GP  CP+ +  + +   +C + C  +C++      C +  C  GC 
Sbjct: 4648 GGCREPWAQESCNGGP--CPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCR 4705

Query: 374  CPEGTVLDDIGQTGCVPVSKCACVYNGA----AYAPGATYSTDCTNCTCSGGRWSCQEVP 429
            CP G ++ D     CVP+S C C    A      AP      DC NCTC      C    
Sbjct: 4706 CPPGQLVQD---GRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQE 4762

Query: 430  CP 431
            CP
Sbjct: 4763 CP 4764



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 41/129 (31%), Positives = 49/129 (37%), Gaps = 21/129 (16%)

Query: 780  GAICTCTHGKLSCIGGQAPAPVCAAPMVFF--DCRNATPGDTGAGCQKSCHTL--DMTCY 835
            G  C     + SC GG  P P C A    F  DC N         C  SC  L   + C 
Sbjct: 4647 GGGCREPWAQESCNGG--PCPECEAQDTVFTLDCANQ--------CPHSCADLWDRVQCL 4696

Query: 836  SPQCVPGCVCPDG-LVADGEGGCITAEDCPCVHNEAS----YRAGQTIRVGCNTCTCDSR 890
               C PGC CP G LV DG   C+    C C    A+        Q +++ C  CTC + 
Sbjct: 4697 QGPCRPGCRCPPGQLVQDGR--CVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNE 4754

Query: 891  MWRCTDDPC 899
               C    C
Sbjct: 4755 SLVCPHQEC 4763



 Score = 51.6 bits (122), Expect = 8e-06
 Identities = 23/62 (37%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 839  CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRM-WRCTDD 897
            C PGC CP G++      C+  +DCPC H    Y  G T+   C  C+C S +   C+  
Sbjct: 3119 CHPGCHCPSGMLLLNNV-CVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSW 3177

Query: 898  PC 899
            PC
Sbjct: 3178 PC 3179



 Score = 51.6 bits (122), Expect = 8e-06
 Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 5/88 (5%)

Query: 351  CADTCSNQEHSRA---CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGA 407
            C  TC     ++    C     +GC C  G      G   CVP   C C + G  + PG+
Sbjct: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGP--CVPEDHCECWHLGRPHLPGS 4997

Query: 408  TYSTDCTNCTCSGGRWSCQEVPCPGTCS 435
             +   C +C C  GR  C +   P TC+
Sbjct: 4998 EWQEACESCLCLSGRPVCTQHCSPLTCA 5025



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 30/132 (22%), Positives = 45/132 (34%), Gaps = 10/132 (7%)

Query: 717  CQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESV 776
            C+ TC  ++      +       GC+C  G F    G CV   +C C+H G     G   
Sbjct: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEW 4999

Query: 777  HDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFD-------CRNATPGDTGAGCQKSCHT 829
             ++   C C  G+  C    +P        +  +       CR   P +    CQ     
Sbjct: 5000 QEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSCQLLTEL 5059

Query: 830  LDM---TCYSPQ 838
             +    TCY  Q
Sbjct: 5060 RNFTKGTCYLDQ 5071



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 56/231 (24%), Positives = 80/231 (34%), Gaps = 37/231 (16%)

Query: 662  CNCERSEDCLCAALSSYVHACA-AKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPT 720
            C+  ++    CAAL   +H+    K     G  +  C+  +   P         + C  T
Sbjct: 1776 CHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQP--------CAPCPLT 1827

Query: 721  CRSLSEGDITCSVGF-IPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDS 779
            C  +S G +TC   +     GC CP+G  L   G CV    CPC   G+    G+ +   
Sbjct: 1828 CDDIS-GQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD 1886

Query: 780  GAICTCTHGK-----------LSC-IGGQAPAPVCAAP-------MVFFDCRNATPGDTG 820
              +C C  G+           + C     +P   C  P         F    N  P   G
Sbjct: 1887 CQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRG 1946

Query: 821  AGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGE---GGCITAEDCPCVHN 868
              C +  H     C +  C  GC     +   GE   GG      C C+HN
Sbjct: 1947 RQC-RGIHRKARRCQTEPC-EGCEHQGQVHRVGERWHGG--PCRVCQCLHN 1993



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 33/116 (28%), Positives = 42/116 (36%), Gaps = 28/116 (24%)

Query: 338  CPNNMQYHECR--SPCADTCSNQEHSRAC-EDHCVAGCFCPEGTVLDDIGQTGCVPVSKC 394
            CP    Y EC+    C  +C++      C  + C  GC CPEGT      Q     V +C
Sbjct: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTF-----QHRLACVQEC 3751

Query: 395  ACVYN--------------------GAAYAPGATYSTDCTNCTCSGGRWSCQEVPC 430
             CV                      G     G T  T C NC+C+ G+ SC    C
Sbjct: 3752 PCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDC 3807



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 40/136 (29%), Positives = 53/136 (38%), Gaps = 21/136 (15%)

Query: 740  GCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLS------CI 793
            GC CP G  L +   CV   +CPC H G + P G +V      C+C  G ++      C 
Sbjct: 3122 GCHCPSGMLLLNN-VCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180

Query: 794  GGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKS-CHTLDMTCYSPQCVPGCVCPDGLVAD 852
             G+   P  +    +  C         A C  + CH       SP  VP  V P  L A 
Sbjct: 3181 EGE---PTWSPWTPWSQC--------SASCGPARCHRHRFCARSPSAVPSTVAPLPLPAT 3229

Query: 853  GEGGCI--TAEDCPCV 866
                C    AE+ PC+
Sbjct: 3230 PTPLCSGPEAEEEPCL 3245



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 42/151 (27%), Positives = 55/151 (36%), Gaps = 41/151 (27%)

Query: 660  DTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYH-VSTCQ 718
            D C   R++  +C AL   V  C A    + G     C  P   CP+S     H V  CQ
Sbjct: 3289 DYCEGPRAQGEVCQALPCPVTNCTA----IEGAEYSPCGPP---CPRSCDDLVHCVWRCQ 3341

Query: 719  PTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGK-CVQASNCPC--------YHRGSM 769
            P                    GC CP G  L   G  CVQ  +C C        +H G+ 
Sbjct: 3342 P--------------------GCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGAR 3381

Query: 770  IPNGESVHDSGAICTCTHGKLSCIGGQAPAP 800
            +   +  +     CTC  G+L+C     P P
Sbjct: 3382 LARPDGCNH----CTCLEGRLNCTDLPCPVP 3408



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 73/311 (23%), Positives = 104/311 (33%), Gaps = 54/311 (17%)

Query: 1175 EWH-YQPCGVPCLRTCRNPRGDCLRDVW-----GLEGCYPKCPPEAPIFDEDKMQCV--- 1225
            EW  + PC VPC    RN      R +      GL+ C    P   P  D+  + C    
Sbjct: 3045 EWGPWSPCSVPCGGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPR-DKQWLDCAQGP 3103

Query: 1226 ATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYNGQRFH 1285
            A+C     P   +   ++  PG   PS     + +C           + C C + G  + 
Sbjct: 3104 ASCAELSAPRGTN---QTCHPGCHCPSGMLLLNNVCVP--------TQDCPCAHEGHLYP 3152

Query: 1286 PGDVIYHTTDGTGGCIS---ARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPLVVSSTH 1342
            PG  +    +    C+S   A C +        +PC+   P    T+S  TP    S++ 
Sbjct: 3153 PGSTVVRPCENCS-CVSGLIANCSS--------WPCAEGEP----TWSPWTPWSQCSASC 3199

Query: 1343 TPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCL------------WS 1390
             P+            SA P+T    P    PT   S P    E CL            W 
Sbjct: 3200 GPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWG 3259

Query: 1391 PWMDVSRPGRGTDSGDFDTLENLRAHGY-RVCESPRS--VECRAEDAPGVPLRAL--GQR 1445
            PW   SR   G         +     G    CE PR+    C+A   P     A+   + 
Sbjct: 3260 PWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPVTNCTAIEGAEY 3319

Query: 1446 VQCSPDVGLTC 1456
              C P    +C
Sbjct: 3320 SPCGPPCPRSC 3330



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 19/97 (19%)

Query: 1178 YQPCGVPCLRTCRNPRGDCLRDVWGLE-GCYPKCPPEAPIFDEDKMQCVATCPTPPLPPR 1236
            Y PCG PC R+C     D +  VW  + GCY  CPP   +   +   CV        P  
Sbjct: 3319 YSPCGPPCPRSC----DDLVHCVWRCQPGCY--CPP-GQVLSSNGAICVQ-------PGH 3364

Query: 1237 CH----VHGKSYRPGAVVPSDKNCQSCLCTERGVECT 1269
            C     + G+ + PGA +     C  C C E  + CT
Sbjct: 3365 CSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCT 3401



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 75/308 (24%), Positives = 101/308 (32%), Gaps = 63/308 (20%)

Query: 1102 TFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSIC 1161
            T A  H+    +++ +AC N  C+C +G   +  CTA                      C
Sbjct: 4120 TDAQGHSWAPGSQHQDACNN--CSCQAG---QLSCTAQP--------------------C 4154

Query: 1162 PLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDK 1221
            P       P   C W +     PC  +C  PRG   R      G +      AP   E++
Sbjct: 4155 P-------PPTHCAWSHWSAWSPCSHSC-GPRGQQSRFRSSTSGSW------APECREEQ 4200

Query: 1222 MQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTY-N 1280
             Q    CP P  PP C + G   R          CQ C CT  GV C    E   C    
Sbjct: 4201 SQS-QPCPQPSCPPLC-LQGTRSRTLGDSWLQGECQRCSCTPEGVIC----EDTECAVPE 4254

Query: 1281 GQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFSFSTP-PLVVS 1339
                         + G G  +  R         R  PC     + P T +   P P ++ 
Sbjct: 4255 AWTLWSSWSDCPVSCGGGNQVRTRACRAAAPHHRSPPC-----LGPDTQTRQQPCPGLLE 4309

Query: 1340 STHTPSNGPSSAHTGP----PSSAWPTTAGTSPRT------RLPTASASLPPVCGEKCLW 1389
            +      GP S   GP     S + P     +  T       L T      P C E+C+W
Sbjct: 4310 ACSWGPWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLDTQGCYSGP-CPEECVW 4368

Query: 1390 SPWMDVSR 1397
            S W   +R
Sbjct: 4369 SSWSSWTR 4376



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 45/197 (22%), Positives = 72/197 (36%), Gaps = 41/197 (20%)

Query: 737  PVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHG------KL 790
            P+ G  CP+  F   +          C+ +   +    ++ ++   C+ + G      + 
Sbjct: 2531 PLPGGSCPRDRFRSQS----------CFVQACPVAGAWAMWEAWGPCSVSCGGGHQSRQR 2580

Query: 791  SCI-----GGQAPAPVCA---APMVFFDCRNATPGDTGAG------CQKSC-HTLDMTCY 835
            SC+      G AP P  +   AP     C   T  + G        CQK        +C 
Sbjct: 2581 SCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCL 2640

Query: 836  SPQ--------CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVG-CNTCT 886
             P+        CV GC CP GL+   +  C+   +CPC+  E     G +  +G C+ C 
Sbjct: 2641 DPKANRSCSGHCVEGCRCPPGLLLH-DTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCV 2699

Query: 887  CDSRMWRCTDDPCLATC 903
            C+     C    C   C
Sbjct: 2700 CEKGELLCQPGGCPLPC 2716



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 63/247 (25%), Positives = 79/247 (31%), Gaps = 71/247 (28%)

Query: 704  CPKSMTYHYHVSTCQPT--CRSLSEGDITCSVGFIPV---DGCICPKGTFLDDTGKCVQA 758
            CP    Y      CQP   C   S   +T  VG       +GC CP+GTF      CVQ 
Sbjct: 3697 CPAGRLYR----ECQPGEGC-PFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLA-CVQ- 3749

Query: 759  SNCPCYHR--------------------GSMIPNGESVHDSGAICTCTHGKLSCIGGQAP 798
              CPC                       G  + +G+++  S   C+C HGKLSC      
Sbjct: 3750 -ECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSC------ 3802

Query: 799  APVCAAPMVFFDCRNAT----PGDTGAGCQKSCHTLDMTCYSPQCV--------PGC--- 843
                       DC  A     P      C +SC  L     S QCV         GC   
Sbjct: 3803 --------SLDDCFEADGGFGPWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGP 3854

Query: 844  ----VCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSR-MWRCTDDP 898
                 CP       EG  +     P       +    +      +CT  +R  WR     
Sbjct: 3855 RQDLECPSPDCPGAEGSTVE----PVTGLPGGWGPWSSWSPCSRSCTDPARPAWRSRTRL 3910

Query: 899  CLATCAV 905
            CLA C +
Sbjct: 3911 CLANCTM 3917



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 53/221 (23%), Positives = 69/221 (31%), Gaps = 74/221 (33%)

Query: 631  CSQ--LTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQ 688
            CSQ  L    GP  R  + + P    S+C  D    E     +C   S +          
Sbjct: 2784 CSQSCLAPGGGPGWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIW---------- 2833

Query: 689  LGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITC----------------- 731
             G W       P +TC  S      + T   +C SL+ GD TC                 
Sbjct: 2834 -GLWA------PWSTC--SAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCTA 2884

Query: 732  ---------------------------------SVGFIPVDGCICPKGTFLDDTGKCVQA 758
                                               GF    GC CP G FL +   C+  
Sbjct: 2885 QCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFC-APGCTCPPGLFLHN-ASCLPR 2942

Query: 759  SNCPCYHRGSMIPNGESVH-DSGAICTCTHGKLSCIGGQAP 798
            S CPC   G +  +G     DS   CTC  GK++C   + P
Sbjct: 2943 SQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCP 2983



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 83/338 (24%), Positives = 110/338 (32%), Gaps = 59/338 (17%)

Query: 1080 PCT-ANPFRKSWAQ-KQCSILHGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCT 1137
            PC    P    W    QCS   GP  A CH H   AR   A  +              C+
Sbjct: 3178 PCAEGEPTWSPWTPWSQCSASCGP--ARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCS 3235

Query: 1138 AVAA-----YAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRT---- 1188
               A       Q C   G    W   S C   C      G      + C  P  +     
Sbjct: 3236 GPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCG-----GGLRSRTRACDQPPPQGLGDY 3290

Query: 1189 CRNPRGD--------C-LRDVWGLEGC-YPKCPPEAPIFDEDKMQCVATCPTPPLPPRCH 1238
            C  PR          C + +   +EG  Y  C P  P   +D + CV  C      P C+
Sbjct: 3291 CEGPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQ-----PGCY 3345

Query: 1239 VHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYNGQRFHPGDVIYHTTDGTG 1298
                   PG V+ S+      +C + G  C+     C+    GQR HPG  +        
Sbjct: 3346 CP-----PGQVLSSN----GAICVQPG-HCS-----CLDLLTGQRHHPGARLAR----PD 3386

Query: 1299 GCISARCGANGTIERRVYPCS-PTTPVPPTTFSFSTPPLVVSSTHTPSNG---PSSAHTG 1354
            GC    C   G +     PC  P    P + ++  + P     T + S     P+  H G
Sbjct: 3387 GCNHCTC-LEGRLNCTDLPCPVPGGWCPWSEWTMCSQP-CRGQTRSRSRACACPTPQHGG 3444

Query: 1355 PPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCLWSPW 1392
             P +     AG +   R    S +  PV G    W PW
Sbjct: 3445 APCTGEAGEAG-AQHQREACPSYATCPVDGAWGPWGPW 3481



 Score = 34.7 bits (78), Expect = 0.97
 Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 15/101 (14%)

Query: 1182 GVPCLRTC--RNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHV 1239
            G PC R C  + P  +C    +   GC   CPP   + +     C+     P     C +
Sbjct: 2902 GGPCPRLCLTQGPGIECTG--FCAPGC--TCPPGLFLHNAS---CLPRSQCP-----CQL 2949

Query: 1240 HGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYN 1280
            HG+ Y  GA+   D +C +C C    + CT +     C ++
Sbjct: 2950 HGQLYASGAMARLD-SCNNCTCVSGKMACTSERCPVACGWS 2989



 Score = 34.7 bits (78), Expect = 0.97
 Identities = 101/421 (23%), Positives = 128/421 (30%), Gaps = 93/421 (22%)

Query: 1068 SPSC--PDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDACA 1125
            SP C  PD    + PC       SW         GP   +C   +       A  + +C 
Sbjct: 4289 SPPCLGPDTQTRQQPCPGLLEACSWGP------WGPCSRSCGPGL-------ASRSGSCP 4335

Query: 1126 C-DSGGDCECFCTAVAAYAQACHEVGLCV---------SWRTPSICPLFCDYYNPEGQCE 1175
            C  +  D  C  T +    Q C+  G C          SW   S   L    Y  +G   
Sbjct: 4336 CLMAKADPTCNSTFLHLDTQGCYS-GPCPEECVWSSWSSWTRCSCRVLVQQRYRHQGPAS 4394

Query: 1176 WHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPT----- 1230
               +  G PC R   + R  CL      + C P  P E   F      C   C T     
Sbjct: 4395 RGAR-AGAPCTRLDGHFR-PCLISNCSEDSCTP--PFE---FHACGSPCAGLCATHLSHQ 4447

Query: 1231 -----PPLPPRCHV-HGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYNGQRF 1284
                 PP  P C+   G   + G  +P ++    C C       T  A A +    G R 
Sbjct: 4448 LCQDLPPCQPGCYCPKGLLEQAGGCIPPEE----CNCWH-----TSAAGAGMTLAPGDRL 4498

Query: 1285 HPGDVIYHTTDGTGGCISARCGANGTIERRVY----PCSPTTPVP--------------- 1325
              G        G   C S  C   G +    +    PC P  P                 
Sbjct: 4499 QLGCKECECRRGELHCTSQGC--QGLLPLSEWSEWSPCGPCLPPSALAPASRTALEEHWL 4556

Query: 1326 --PTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWP--TTAGTSPRTRLPTASASLPP 1381
              PT  S +  PL+ S  H        A TG P +  P   TA  S +   P      P 
Sbjct: 4557 RDPTGLSPTLAPLLASEQHRHRLCLDPA-TGRPWTGAPHLCTAPLSQQRLCPD-----PG 4610

Query: 1382 VCGEKC---LWSPWMDVSRPGRGTDSGDFDTLENLRAHGYR------VCESPRSVECRAE 1432
             C + C   LW PW     P  G     +   E L   G R       C      EC A+
Sbjct: 4611 ACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPECEAQ 4670

Query: 1433 D 1433
            D
Sbjct: 4671 D 4671



 Score = 34.7 bits (78), Expect = 0.97
 Identities = 68/327 (20%), Positives = 97/327 (29%), Gaps = 98/327 (29%)

Query: 1063 NSWKLSPSC--PDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACV 1120
            + W     C  P ALAP    +     + W +    +   PT A   A  +    +  C+
Sbjct: 4529 SEWSPCGPCLPPSALAP---ASRTALEEHWLRDPTGL--SPTLAPLLASEQ--HRHRLCL 4581

Query: 1121 NDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWH--- 1177
            + A      G     CTA  +  + C + G C                     C+W    
Sbjct: 4582 DPATGRPWTG-APHLCTAPLSQQRLCPDPGACPD------------------SCQWSLWG 4622

Query: 1178 -YQPCGVPCL-------RTCRNPRGDCLRDVWGLEGCY----PKCPPEAPIFDEDKMQCV 1225
             + PC VPC        R      G   R+ W  E C     P+C  +  +F  D   C 
Sbjct: 4623 PWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLD---CA 4679

Query: 1226 ATCPTP-------------PLPPRCHVH-GKSYRPGAVVPSDK----------------- 1254
              CP               P  P C    G+  + G  VP                    
Sbjct: 4680 NQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPA 4739

Query: 1255 -----NCQSCLCTERGVECTYKA----------EACVCTYNGQRFHPGDVIYHTTDGTGG 1299
                 +CQ+C C    + C ++            +C     G     G +  H T   GG
Sbjct: 4740 QAVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSSCSAPCGG-----GTMERHRT-CEGG 4793

Query: 1300 CISARCGANGTIERRVYPCSPTTPVPP 1326
               A C A  T +R+     P    PP
Sbjct: 4794 PGVAPCQAQDTEQRQECNLQPCPECPP 4820



 Score = 33.9 bits (76), Expect = 1.7
 Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 23/107 (21%)

Query: 1180 PCGVPCLRTCR--NPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRC 1237
            PCG PC R+C+  +P   C     G  GC P C        +D + CV     PP   RC
Sbjct: 3537 PCGQPCPRSCQDLSPGSVCQP---GSVGCQPTCGCPLGQLSQDGL-CV-----PPAHCRC 3587

Query: 1238 HVHGKSYRPGAV-VPSDKN------CQSCLCTERGVECTYKAEACVC 1277
                  Y+PGA+ +P +++        S    E G   T   + C C
Sbjct: 3588 -----QYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTC 3629



 Score = 32.3 bits (72), Expect = 4.8
 Identities = 32/113 (28%), Positives = 39/113 (34%), Gaps = 22/113 (19%)

Query: 1381 PVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLR 1440
            PV GE   WSPW   S P RGT +              R C SP++        PG  L 
Sbjct: 1748 PVDGEWSTWSPWSVCSEPCRGTMTRQ------------RQCHSPQNGGRTCAALPG-GLH 1794

Query: 1441 ALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSSSPAQTTPP 1493
            +  Q   C  D    C N   +  L +      Q C P   +      Q T P
Sbjct: 1795 STRQTKPCPQD---GCPNATCSGELMF------QPCAPCPLTCDDISGQVTCP 1838


>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
            sapiens]
          Length = 2250

 Score =  597 bits (1540), Expect = e-170
 Identities = 363/1134 (32%), Positives = 551/1134 (48%), Gaps = 100/1134 (8%)

Query: 77   NGR--VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLS 134
            NGR  +C TWG +H++TFDG  + FPG C+Y+F++ CG     + + +  S +      S
Sbjct: 58   NGRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYS 117

Query: 135  RV----LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWN 190
                  L   +   I++    +  NG  + LP +   + I++ + Y  V+   G  L W+
Sbjct: 118  CYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWD 177

Query: 191  HDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME-FGNLQKMDDPTE-QC 248
                + L+L   +  K+CGLCG++N +     ++        +  F N   +  P + +C
Sbjct: 178  GISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKC 237

Query: 249  QDPVPEPPRNCSTG-------FGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDT 301
                 + P  CS+G       F  C+ LL     S C   +D   Y+ +C  DLC  +D 
Sbjct: 238  VLTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLS-CHEYIDPYLYIASCVNDLCKTDDD 296

Query: 302  DLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDF--CPQKCPNNMQYHECRSPCADTCSNQE 359
            +     C    EY+R C+HAG   QDWR  DF  C  KC ++  + +C S C  TC+ ++
Sbjct: 297  ETY---CRAATEYARACSHAGYPIQDWRD-DFPACTDKCDDSFVHRDCISCCPPTCTFEK 352

Query: 360  HSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCS 419
                   HC+ GC+CP+G V+D+     C+ +  C C ++G AY+ G+    +CT C C 
Sbjct: 353  QCLGSNLHCLDGCYCPDGLVMDN---GTCISLENCPCGFHGLAYSVGSKIEQECTECVCV 409

Query: 420  GGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCG 479
            GG W+C E  CP  CSV+G +HF+TFDG+ Y+  G C Y+L K      FT+  +   C 
Sbjct: 410  GGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCE 469

Query: 480  LTDSETCLKSVTLSL-DGVQTVVVIKASGEVFL--NQIYTQLPISAANVTIFRPSTFFII 536
                  CL+S+TL L D     V +   G++    NQ +    I    V I   S+ FI+
Sbjct: 470  QNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGI----VEIQTLSSLFIL 525

Query: 537  AQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAF 596
             +T+ GL++ L  +   ++++QL    + +T GLCG FN    DDF + SG++E T    
Sbjct: 526  LKTTFGLKI-LFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLH 584

Query: 597  FNTFKTQAAC-PNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYS 655
             N ++  + C   +     DPC+++ +N  YA H C  +      F  CH  + PG YY 
Sbjct: 585  ANAWRVSSTCFAPVHVPVVDPCNINQQNIGYAAH-CDVIHQE--LFAPCHIYISPGLYYQ 641

Query: 656  NCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVS 715
             C  D C C  S  CLC AL+ Y + C   GV +  +R  +    +  C K M YH+  S
Sbjct: 642  LCRHDACKCGSS--CLCNALAHYAYLCGQHGVPID-FRTQISFCAVV-CQKGMLYHHCSS 697

Query: 716  TCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDT-GKCVQASNCPCYHRGSMIPNGE 774
             C  +C SLS  +  CS      +GC CP+G F +DT   CV   +C C++RGS+   GE
Sbjct: 698  FCLHSCISLSSPE-QCSDDC--AEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGE 754

Query: 775  SVHDSGAICTCTHGKLSCIGGQAPAPV--CAAPMVFFDCRNATPG--DTGAGCQKSCHTL 830
             +     +C C++G + C     P+ V  C     +FDCR   P     G  C+ +C  L
Sbjct: 755  LIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANL 814

Query: 831  DM--TCY-SPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTC 887
             M  TC  S  C+ GCVC  G+                                     C
Sbjct: 815  AMNFTCTPSSPCISGCVCAPGV-------------------------------------C 837

Query: 888  DSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVV 947
               M+ CT  PC A C +YGD HY +FDG  Y +  DC+  L+      K +      V+
Sbjct: 838  RRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLI------KSADDSDISVI 891

Query: 948  TENVPCGTTGTTCSKAIKIFLGGFELKLSHG--KVEVIGTDESQEVPYTIRQMGIYLVVD 1005
             +N  C      CSK++ I +G  E+ L+    K +  G     +  Y + + G Y+VV 
Sbjct: 892  AQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTYQLWKAGYYIVVY 951

Query: 1006 -TDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNS 1064
              +  + +LWD+KT+I I + P++K ++ GLCGNFD    ND  T +   V +   FG+S
Sbjct: 952  FPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDS 1011

Query: 1065 WKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDAC 1124
            W L   C        PC A+  +  +A+K+CSIL+   FA+C   ++   + + C  D C
Sbjct: 1012 WALG-QCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTC 1070

Query: 1125 ACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWHY 1178
             C+ GGDCEC CT++AAYA  C + G+ + WR+ ++C L C+YYN EG  E  Y
Sbjct: 1071 NCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDCEYYN-EGLGEGPY 1123



 Score =  228 bits (580), Expect = 6e-59
 Identities = 148/461 (32%), Positives = 218/461 (47%), Gaps = 47/461 (10%)

Query: 823  CQKSCHTLDMTCYSPQ--CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRV 880
            C  +C T +  C      C+ GC CPDGLV D  G CI+ E+CPC  +  +Y  G  I  
Sbjct: 344  CPPTC-TFEKQCLGSNLHCLDGCYCPDGLVMDN-GTCISLENCPCGFHGLAYSVGSKIEQ 401

Query: 881  GCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDST 940
             C  C C   +W CT+  C   C+V GD H+ TFDG+ YSF G C+Y LV      K + 
Sbjct: 402  ECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILV------KGTG 455

Query: 941  QDSFRVVTENVPCGTT-GTTCSKAIKIFL-GGFELKLSHGKVEVIGTDESQEVPYT---- 994
            +D F +  +  PC    G  C ++I + L   F  +++ G+   I T  +Q         
Sbjct: 456  KDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVE 515

Query: 995  IRQMG-IYLVVDTDIGLVLLWD-KKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSR 1052
            I+ +  +++++ T  GL +L+      I+I L+  +K R  GLCG F+    +DF + S 
Sbjct: 516  IQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSG 575

Query: 1053 SVVGDVLEFGNSWKLSPSC--PDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHV 1110
             + G      N+W++S +C  P  +   DPC  N     +A   C ++H   FA CH ++
Sbjct: 576  MIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGYAA-HCDVIHQELFAPCHIYI 634

Query: 1111 EPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTP-SICPLFCDYYN 1169
             P  YY+ C +DAC C S     C C A+A YA  C + G+ + +RT  S C + C    
Sbjct: 635  SPGLYYQLCRHDACKCGSS----CLCNALAHYAYLCGQHGVPIDFRTQISFCAVVC---- 686

Query: 1170 PEGQCEWHYQPCGVPCLRTCRNPRG--DCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVAT 1227
               Q    Y  C   CL +C +      C  D    EGC   CP E   +++    CV  
Sbjct: 687  ---QKGMLYHHCSSFCLHSCISLSSPEQCSDDC--AEGC--NCP-EGKFYEDTLNFCV-- 736

Query: 1228 CPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVEC 1268
               P    RCH  G  Y+PG ++P+      C C+   V+C
Sbjct: 737  ---PIFHCRCHYRGSVYQPGELIPTPSGL--CQCSNGTVKC 772



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 122/499 (24%), Positives = 195/499 (39%), Gaps = 88/499 (17%)

Query: 719  PTCRSLSEGDITCSVGFIPVDGCI--CPKGTFLDD-TGKCVQASNCPCYHRGSMIPNGES 775
            P  ++ S+ +        PV+GC+  CPK   LD+ T KCV   +C       +IP   +
Sbjct: 1287 PCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCI-----PVIPTEPT 1341

Query: 776  VHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGC--QKSCHTLDMT 833
            +                I    P+ +    M+       TP  TG  C  QK     D +
Sbjct: 1342 LMPPAKPTVPMFTVWEMI---TPSDITVFDML-------TP-TTGLECEPQKFDPVYDCS 1390

Query: 834  CYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWR 893
             Y       C+  +  + +    C    + P    +  +R G+ ++V  + C  +   W 
Sbjct: 1391 QYI------CLNMEWQLYNWSLNCPKDVEMP----DCGFR-GRPVQVNSDICCPE---WE 1436

Query: 894  CTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPC 953
            C   PC   C++  +   +TFDG + +      Y LV+    G+       +      P 
Sbjct: 1437 C---PC--RCSMLSELSIITFDGNNAALYSMASYILVR--IPGEIIVAHIEKCSMNQAPS 1489

Query: 954  GTTGTTCSKAI-------KIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDT 1006
            G     C K +       KI +     K+    + V     SQE+  +I   G   V+ T
Sbjct: 1490 GRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQEL--SIEDSGSMYVITT 1547

Query: 1007 DIGLVLLWDKKTSIF-------INLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVL 1059
              GL++ W   T I         NLS   +G +CG+C    D   +D   ++ +++ ++ 
Sbjct: 1548 PAGLIIKWSHLTGIIDIHFGFRFNLSSYTEG-LCGICNEDPD---DDLRMQNGTIITNME 1603

Query: 1060 EFG---NSWKLSPSCPDALA-PKDPCTANPFRKSWAQKQC-SILHGPTFAACHAHVEPAR 1114
            + G    SW++  S    +  P   CT +         QC  +L+   F  CH  V P  
Sbjct: 1604 DIGLFIESWEIEKSFEVTMRRPVRNCTEHDC------SQCIDLLNRRIFIPCHDKVSPED 1657

Query: 1115 YYEAC-VNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQ 1173
            + E   +N     +        C A++AY   C++  +C+ WRTP  C L C    PEG+
Sbjct: 1658 FCEKMWINYTYFWNYE------CDALSAYVALCNKFDICIQWRTPDYCSLSC----PEGK 1707

Query: 1174 CEWHYQPCGVPC-LRTCRN 1191
                YQPC  PC  RTC N
Sbjct: 1708 ---EYQPCVRPCEARTCLN 1723



 Score = 87.8 bits (216), Expect = 1e-16
 Identities = 100/436 (22%), Positives = 158/436 (36%), Gaps = 48/436 (11%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPT--LSRVLM 138
            CS        TFDG+      + +Y+     G   E     + +   + AP+  +S +  
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPG---EIIVAHIEKCSMNQAPSGRISGLCF 1497

Query: 139  K-------VDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNH 191
            K       +  +++      V V+   V LPFS   + I+ S S   +    GL++ W+H
Sbjct: 1498 KKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSH 1557

Query: 192  DDSLL---LELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME-FGNLQKMDDPTEQ 247
               ++          ++ T GLCG  N  P     + + T +T ME  G   +  +  + 
Sbjct: 1558 LTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKS 1617

Query: 248  CQDPVPEPPRNCST-GFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSC 306
             +  +  P RNC+      C +LL+ ++F  C   V    + E       +   T   + 
Sbjct: 1618 FEVTMRRPVRNCTEHDCSQCIDLLNRRIFIPCHDKVSPEDFCEKM-----WINYTYFWNY 1672

Query: 307  VCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPC-ADTCSNQ-EHSRAC 364
             C  L+ Y   C       Q WR PD+C   CP   +Y  C  PC A TC NQ  +    
Sbjct: 1673 ECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTS 1731

Query: 365  EDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACV-YNGAAYAPGATYSTDCTNCTCSGGRW 423
              +    C C  GTVL       C+P  +CAC          G  ++     CT     +
Sbjct: 1732 CLNLREDCVCKVGTVLHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTL----Y 1787

Query: 424  SCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDS 483
             C E                  +G    +  DC    T  C+  A  V+  + +      
Sbjct: 1788 KCLE------------------NGSIIPIEPDCDEEPTPVCEREAEVVMGIIDKWTCCSK 1829

Query: 484  ETCLKSVTLSLDGVQT 499
            E C    TL    + T
Sbjct: 1830 EVCGCDTTLCETSIPT 1845



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 123/527 (23%), Positives = 187/527 (35%), Gaps = 58/527 (11%)

Query: 425  CQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD-- 482
            C E  CP  CS+L      TFDG    ++   SY+L +        ++A + +C +    
Sbjct: 1432 CPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVR---IPGEIIVAHIEKCSMNQAP 1488

Query: 483  ----SETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQ 538
                S  C K + ++   +  ++V + + +V ++ I   LP S+  ++I    + ++I  
Sbjct: 1489 SGRISGLCFKKLNVTTP-IHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVIT- 1546

Query: 539  TSLGLQLN-LQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEAT---AA 594
            T  GL +    L   + +       L   T GLCG  N    DD R  +G +        
Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606

Query: 595  AFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGP--FGRCHAAVKPGT 652
             F  +++       I  SFE      V N    +H CSQ  D      F  CH  V P  
Sbjct: 1607 LFIESWE-------IEKSFEVTMRRPVRN--CTEHDCSQCIDLLNRRIFIPCHDKVSPED 1657

Query: 653  YYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHY 712
            +   C     N     +  C ALS+YV  C    + +       C+    +CP+   Y  
Sbjct: 1658 F---CEKMWINYTYFWNYECDALSAYVALCNKFDICIQWRTPDYCS---LSCPEGKEYQP 1711

Query: 713  HVSTCQP-TC-RSLSEGDITCSVGFIPVDGCICPKGTFL--DDTGKCVQASNCPCYHRGS 768
             V  C+  TC      G  +C       + C+C  GT L    + +C+    C C     
Sbjct: 1712 CVRPCEARTCLNQWFYGHTSC---LNLREDCVCKVGTVLHRPHSAQCIPEKECACTDSED 1768

Query: 769  MIPNGESVHDSGAICTCTHGKLSCIGG---------QAPAPVC----AAPMVFFDCRNAT 815
              P       +G I  CT  K    G          + P PVC       M   D     
Sbjct: 1769 Q-PRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCEREAEVVMGIIDKWTCC 1827

Query: 816  PGDTGAGCQKS-CHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRA 874
              +   GC  + C T   TC + Q +     P       +  C   + CP +        
Sbjct: 1828 SKEV-CGCDTTLCETSIPTCTNSQKLIVGHSPLSCCPQYKCECDPLK-CPSISTPECRED 1885

Query: 875  GQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSF 921
               I+V      C S    C  + C     +  DG +LT D  S  F
Sbjct: 1886 QFMIQVRQEEPCCFSPF--CVCESCTKPVPLCHDGEFLTVDLNSTHF 1930



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 34/103 (33%), Positives = 44/103 (42%), Gaps = 9/103 (8%)

Query: 1174 CEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCV---ATCPT 1230
            CEW Y+PC  PC +TC +P     + +  +EGC P CP    I DE  ++CV      P 
Sbjct: 1277 CEWRYEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNM-ILDEVTLKCVYPRDCIPV 1335

Query: 1231 PPLPPRCHVHGKSYRP-----GAVVPSDKNCQSCLCTERGVEC 1268
             P  P      K   P       + PSD      L    G+EC
Sbjct: 1336 IPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLEC 1378



 Score = 34.3 bits (77), Expect = 1.3
 Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 9/57 (15%)

Query: 343  QYHECRSPCADTCSNQEHSRACED-HCVAGC--FCPEGTVLDDIG-----QTGCVPV 391
            +Y  C +PC  TCS+ E + AC+    V GC  +CP+  +LD++         C+PV
Sbjct: 1280 RYEPCATPCFKTCSDPE-ALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPV 1335


>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
            sapiens]
          Length = 2250

 Score =  597 bits (1540), Expect = e-170
 Identities = 363/1134 (32%), Positives = 551/1134 (48%), Gaps = 100/1134 (8%)

Query: 77   NGR--VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLS 134
            NGR  +C TWG +H++TFDG  + FPG C+Y+F++ CG     + + +  S +      S
Sbjct: 58   NGRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYS 117

Query: 135  RV----LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWN 190
                  L   +   I++    +  NG  + LP +   + I++ + Y  V+   G  L W+
Sbjct: 118  CYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWD 177

Query: 191  HDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME-FGNLQKMDDPTE-QC 248
                + L+L   +  K+CGLCG++N +     ++        +  F N   +  P + +C
Sbjct: 178  GISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKC 237

Query: 249  QDPVPEPPRNCSTG-------FGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDT 301
                 + P  CS+G       F  C+ LL     S C   +D   Y+ +C  DLC  +D 
Sbjct: 238  VLTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLS-CHEYIDPYLYIASCVNDLCKTDDD 296

Query: 302  DLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDF--CPQKCPNNMQYHECRSPCADTCSNQE 359
            +     C    EY+R C+HAG   QDWR  DF  C  KC ++  + +C S C  TC+ ++
Sbjct: 297  ETY---CRAATEYARACSHAGYPIQDWRD-DFPACTDKCDDSFVHRDCISCCPPTCTFEK 352

Query: 360  HSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCS 419
                   HC+ GC+CP+G V+D+     C+ +  C C ++G AY+ G+    +CT C C 
Sbjct: 353  QCLGSNLHCLDGCYCPDGLVMDN---GTCISLENCPCGFHGLAYSVGSKIEQECTECVCV 409

Query: 420  GGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCG 479
            GG W+C E  CP  CSV+G +HF+TFDG+ Y+  G C Y+L K      FT+  +   C 
Sbjct: 410  GGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCE 469

Query: 480  LTDSETCLKSVTLSL-DGVQTVVVIKASGEVFL--NQIYTQLPISAANVTIFRPSTFFII 536
                  CL+S+TL L D     V +   G++    NQ +    I    V I   S+ FI+
Sbjct: 470  QNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGI----VEIQTLSSLFIL 525

Query: 537  AQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAF 596
             +T+ GL++ L  +   ++++QL    + +T GLCG FN    DDF + SG++E T    
Sbjct: 526  LKTTFGLKI-LFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLH 584

Query: 597  FNTFKTQAAC-PNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYS 655
             N ++  + C   +     DPC+++ +N  YA H C  +      F  CH  + PG YY 
Sbjct: 585  ANAWRVSSTCFAPVHVPVVDPCNINQQNIGYAAH-CDVIHQE--LFAPCHIYISPGLYYQ 641

Query: 656  NCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVS 715
             C  D C C  S  CLC AL+ Y + C   GV +  +R  +    +  C K M YH+  S
Sbjct: 642  LCRHDACKCGSS--CLCNALAHYAYLCGQHGVPID-FRTQISFCAVV-CQKGMLYHHCSS 697

Query: 716  TCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDT-GKCVQASNCPCYHRGSMIPNGE 774
             C  +C SLS  +  CS      +GC CP+G F +DT   CV   +C C++RGS+   GE
Sbjct: 698  FCLHSCISLSSPE-QCSDDC--AEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGE 754

Query: 775  SVHDSGAICTCTHGKLSCIGGQAPAPV--CAAPMVFFDCRNATPG--DTGAGCQKSCHTL 830
             +     +C C++G + C     P+ V  C     +FDCR   P     G  C+ +C  L
Sbjct: 755  LIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANL 814

Query: 831  DM--TCY-SPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTC 887
             M  TC  S  C+ GCVC  G+                                     C
Sbjct: 815  AMNFTCTPSSPCISGCVCAPGV-------------------------------------C 837

Query: 888  DSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVV 947
               M+ CT  PC A C +YGD HY +FDG  Y +  DC+  L+      K +      V+
Sbjct: 838  RRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLI------KSADDSDISVI 891

Query: 948  TENVPCGTTGTTCSKAIKIFLGGFELKLSHG--KVEVIGTDESQEVPYTIRQMGIYLVVD 1005
             +N  C      CSK++ I +G  E+ L+    K +  G     +  Y + + G Y+VV 
Sbjct: 892  AQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTYQLWKAGYYIVVY 951

Query: 1006 -TDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNS 1064
              +  + +LWD+KT+I I + P++K ++ GLCGNFD    ND  T +   V +   FG+S
Sbjct: 952  FPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDS 1011

Query: 1065 WKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDAC 1124
            W L   C        PC A+  +  +A+K+CSIL+   FA+C   ++   + + C  D C
Sbjct: 1012 WALG-QCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTC 1070

Query: 1125 ACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWHY 1178
             C+ GGDCEC CT++AAYA  C + G+ + WR+ ++C L C+YYN EG  E  Y
Sbjct: 1071 NCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDCEYYN-EGLGEGPY 1123



 Score =  228 bits (580), Expect = 6e-59
 Identities = 148/461 (32%), Positives = 218/461 (47%), Gaps = 47/461 (10%)

Query: 823  CQKSCHTLDMTCYSPQ--CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRV 880
            C  +C T +  C      C+ GC CPDGLV D  G CI+ E+CPC  +  +Y  G  I  
Sbjct: 344  CPPTC-TFEKQCLGSNLHCLDGCYCPDGLVMDN-GTCISLENCPCGFHGLAYSVGSKIEQ 401

Query: 881  GCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDST 940
             C  C C   +W CT+  C   C+V GD H+ TFDG+ YSF G C+Y LV      K + 
Sbjct: 402  ECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILV------KGTG 455

Query: 941  QDSFRVVTENVPCGTT-GTTCSKAIKIFL-GGFELKLSHGKVEVIGTDESQEVPYT---- 994
            +D F +  +  PC    G  C ++I + L   F  +++ G+   I T  +Q         
Sbjct: 456  KDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVE 515

Query: 995  IRQMG-IYLVVDTDIGLVLLWD-KKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSR 1052
            I+ +  +++++ T  GL +L+      I+I L+  +K R  GLCG F+    +DF + S 
Sbjct: 516  IQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSG 575

Query: 1053 SVVGDVLEFGNSWKLSPSC--PDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHV 1110
             + G      N+W++S +C  P  +   DPC  N     +A   C ++H   FA CH ++
Sbjct: 576  MIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGYAA-HCDVIHQELFAPCHIYI 634

Query: 1111 EPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTP-SICPLFCDYYN 1169
             P  YY+ C +DAC C S     C C A+A YA  C + G+ + +RT  S C + C    
Sbjct: 635  SPGLYYQLCRHDACKCGSS----CLCNALAHYAYLCGQHGVPIDFRTQISFCAVVC---- 686

Query: 1170 PEGQCEWHYQPCGVPCLRTCRNPRG--DCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVAT 1227
               Q    Y  C   CL +C +      C  D    EGC   CP E   +++    CV  
Sbjct: 687  ---QKGMLYHHCSSFCLHSCISLSSPEQCSDDC--AEGC--NCP-EGKFYEDTLNFCV-- 736

Query: 1228 CPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVEC 1268
               P    RCH  G  Y+PG ++P+      C C+   V+C
Sbjct: 737  ---PIFHCRCHYRGSVYQPGELIPTPSGL--CQCSNGTVKC 772



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 122/499 (24%), Positives = 195/499 (39%), Gaps = 88/499 (17%)

Query: 719  PTCRSLSEGDITCSVGFIPVDGCI--CPKGTFLDD-TGKCVQASNCPCYHRGSMIPNGES 775
            P  ++ S+ +        PV+GC+  CPK   LD+ T KCV   +C       +IP   +
Sbjct: 1287 PCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCI-----PVIPTEPT 1341

Query: 776  VHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGC--QKSCHTLDMT 833
            +                I    P+ +    M+       TP  TG  C  QK     D +
Sbjct: 1342 LMPPAKPTVPMFTVWEMI---TPSDITVFDML-------TP-TTGLECEPQKFDPVYDCS 1390

Query: 834  CYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWR 893
             Y       C+  +  + +    C    + P    +  +R G+ ++V  + C  +   W 
Sbjct: 1391 QYI------CLNMEWQLYNWSLNCPKDVEMP----DCGFR-GRPVQVNSDICCPE---WE 1436

Query: 894  CTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPC 953
            C   PC   C++  +   +TFDG + +      Y LV+    G+       +      P 
Sbjct: 1437 C---PC--RCSMLSELSIITFDGNNAALYSMASYILVR--IPGEIIVAHIEKCSMNQAPS 1489

Query: 954  GTTGTTCSKAI-------KIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDT 1006
            G     C K +       KI +     K+    + V     SQE+  +I   G   V+ T
Sbjct: 1490 GRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQEL--SIEDSGSMYVITT 1547

Query: 1007 DIGLVLLWDKKTSIF-------INLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVL 1059
              GL++ W   T I         NLS   +G +CG+C    D   +D   ++ +++ ++ 
Sbjct: 1548 PAGLIIKWSHLTGIIDIHFGFRFNLSSYTEG-LCGICNEDPD---DDLRMQNGTIITNME 1603

Query: 1060 EFG---NSWKLSPSCPDALA-PKDPCTANPFRKSWAQKQC-SILHGPTFAACHAHVEPAR 1114
            + G    SW++  S    +  P   CT +         QC  +L+   F  CH  V P  
Sbjct: 1604 DIGLFIESWEIEKSFEVTMRRPVRNCTEHDC------SQCIDLLNRRIFIPCHDKVSPED 1657

Query: 1115 YYEAC-VNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQ 1173
            + E   +N     +        C A++AY   C++  +C+ WRTP  C L C    PEG+
Sbjct: 1658 FCEKMWINYTYFWNYE------CDALSAYVALCNKFDICIQWRTPDYCSLSC----PEGK 1707

Query: 1174 CEWHYQPCGVPC-LRTCRN 1191
                YQPC  PC  RTC N
Sbjct: 1708 ---EYQPCVRPCEARTCLN 1723



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 99/436 (22%), Positives = 158/436 (36%), Gaps = 48/436 (11%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPT--LSRVLM 138
            CS        TFDG+      + +Y+     G   E     + +   + AP+  +S +  
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPG---EIIVAHIEKCSMNQAPSGRISGLCF 1497

Query: 139  K-------VDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNH 191
            K       +  +++      V V+   V LPFS   + I+ S S   +    GL++ W+H
Sbjct: 1498 KKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSH 1557

Query: 192  DDSLL---LELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME-FGNLQKMDDPTEQ 247
               ++          ++ T GLCG  N  P     + + T +T ME  G   +  +  + 
Sbjct: 1558 LTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKS 1617

Query: 248  CQDPVPEPPRNCST-GFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSC 306
             +  +  P RNC+      C +LL+ ++F  C   V    + E       +   T   + 
Sbjct: 1618 FEVTMRRPVRNCTEHDCSQCIDLLNRRIFIPCHDKVSPEDFCEKM-----WINYTYFWNY 1672

Query: 307  VCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPC-ADTCSNQ-EHSRAC 364
             C  L+ Y   C       Q WR PD+C   CP   +Y  C  PC A TC NQ  +    
Sbjct: 1673 ECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTS 1731

Query: 365  EDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACV-YNGAAYAPGATYSTDCTNCTCSGGRW 423
              +    C C  GT+L       C+P  +CAC          G  ++     CT     +
Sbjct: 1732 CLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTL----Y 1787

Query: 424  SCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDS 483
             C E                  +G    +  DC    T  C+  A  V+  + +      
Sbjct: 1788 KCLE------------------NGSIIPIEPDCDEEPTPVCEREAEVVMGIIDKWTCCSK 1829

Query: 484  ETCLKSVTLSLDGVQT 499
            E C    TL    + T
Sbjct: 1830 EVCGCDTTLCETSIPT 1845



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 123/527 (23%), Positives = 187/527 (35%), Gaps = 58/527 (11%)

Query: 425  CQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD-- 482
            C E  CP  CS+L      TFDG    ++   SY+L +        ++A + +C +    
Sbjct: 1432 CPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVR---IPGEIIVAHIEKCSMNQAP 1488

Query: 483  ----SETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQ 538
                S  C K + ++   +  ++V + + +V ++ I   LP S+  ++I    + ++I  
Sbjct: 1489 SGRISGLCFKKLNVTTP-IHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVIT- 1546

Query: 539  TSLGLQLN-LQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEAT---AA 594
            T  GL +    L   + +       L   T GLCG  N    DD R  +G +        
Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606

Query: 595  AFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGP--FGRCHAAVKPGT 652
             F  +++       I  SFE      V N    +H CSQ  D      F  CH  V P  
Sbjct: 1607 LFIESWE-------IEKSFEVTMRRPVRN--CTEHDCSQCIDLLNRRIFIPCHDKVSPED 1657

Query: 653  YYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHY 712
            +   C     N     +  C ALS+YV  C    + +       C+    +CP+   Y  
Sbjct: 1658 F---CEKMWINYTYFWNYECDALSAYVALCNKFDICIQWRTPDYCS---LSCPEGKEYQP 1711

Query: 713  HVSTCQP-TC-RSLSEGDITCSVGFIPVDGCICPKGTFL--DDTGKCVQASNCPCYHRGS 768
             V  C+  TC      G  +C       + C+C  GT L    + +C+    C C     
Sbjct: 1712 CVRPCEARTCLNQWFYGHTSC---LNLREDCVCKVGTILHRPHSAQCIPEKECACTDSED 1768

Query: 769  MIPNGESVHDSGAICTCTHGKLSCIGG---------QAPAPVC----AAPMVFFDCRNAT 815
              P       +G I  CT  K    G          + P PVC       M   D     
Sbjct: 1769 Q-PRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCEREAEVVMGIIDKWTCC 1827

Query: 816  PGDTGAGCQKS-CHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRA 874
              +   GC  + C T   TC + Q +     P       +  C   + CP +        
Sbjct: 1828 SKEV-CGCDTTLCETSIPTCTNSQKLIVGHSPLSCCPQYKCECDPLK-CPSISTPECRED 1885

Query: 875  GQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSF 921
               I+V      C S    C  + C     +  DG +LT D  S  F
Sbjct: 1886 QFMIQVRQEEPCCFSPF--CVCESCTKPVPLCHDGEFLTVDLNSTHF 1930



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 34/103 (33%), Positives = 44/103 (42%), Gaps = 9/103 (8%)

Query: 1174 CEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCV---ATCPT 1230
            CEW Y+PC  PC +TC +P     + +  +EGC P CP    I DE  ++CV      P 
Sbjct: 1277 CEWRYEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNM-ILDEVTLKCVYPRDCIPV 1335

Query: 1231 PPLPPRCHVHGKSYRP-----GAVVPSDKNCQSCLCTERGVEC 1268
             P  P      K   P       + PSD      L    G+EC
Sbjct: 1336 IPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLEC 1378



 Score = 34.3 bits (77), Expect = 1.3
 Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 9/57 (15%)

Query: 343  QYHECRSPCADTCSNQEHSRACED-HCVAGC--FCPEGTVLDDIG-----QTGCVPV 391
            +Y  C +PC  TCS+ E + AC+    V GC  +CP+  +LD++         C+PV
Sbjct: 1280 RYEPCATPCFKTCSDPE-ALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPV 1335


>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens]
          Length = 2250

 Score =  597 bits (1540), Expect = e-170
 Identities = 363/1134 (32%), Positives = 551/1134 (48%), Gaps = 100/1134 (8%)

Query: 77   NGR--VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLS 134
            NGR  +C TWG +H++TFDG  + FPG C+Y+F++ CG     + + +  S +      S
Sbjct: 58   NGRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYS 117

Query: 135  RV----LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWN 190
                  L   +   I++    +  NG  + LP +   + I++ + Y  V+   G  L W+
Sbjct: 118  CYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWD 177

Query: 191  HDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME-FGNLQKMDDPTE-QC 248
                + L+L   +  K+CGLCG++N +     ++        +  F N   +  P + +C
Sbjct: 178  GISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKC 237

Query: 249  QDPVPEPPRNCSTG-------FGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDT 301
                 + P  CS+G       F  C+ LL     S C   +D   Y+ +C  DLC  +D 
Sbjct: 238  VLTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLS-CHEYIDPYLYIASCVNDLCKTDDD 296

Query: 302  DLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDF--CPQKCPNNMQYHECRSPCADTCSNQE 359
            +     C    EY+R C+HAG   QDWR  DF  C  KC ++  + +C S C  TC+ ++
Sbjct: 297  ETY---CRAATEYARACSHAGYPIQDWRD-DFPACTDKCDDSFVHRDCISCCPPTCTFEK 352

Query: 360  HSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCS 419
                   HC+ GC+CP+G V+D+     C+ +  C C ++G AY+ G+    +CT C C 
Sbjct: 353  QCLGSNLHCLDGCYCPDGLVMDN---GTCISLENCPCGFHGLAYSVGSKIEQECTECVCV 409

Query: 420  GGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCG 479
            GG W+C E  CP  CSV+G +HF+TFDG+ Y+  G C Y+L K      FT+  +   C 
Sbjct: 410  GGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCE 469

Query: 480  LTDSETCLKSVTLSL-DGVQTVVVIKASGEVFL--NQIYTQLPISAANVTIFRPSTFFII 536
                  CL+S+TL L D     V +   G++    NQ +    I    V I   S+ FI+
Sbjct: 470  QNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGI----VEIQTLSSLFIL 525

Query: 537  AQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAF 596
             +T+ GL++ L  +   ++++QL    + +T GLCG FN    DDF + SG++E T    
Sbjct: 526  LKTTFGLKI-LFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLH 584

Query: 597  FNTFKTQAAC-PNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYS 655
             N ++  + C   +     DPC+++ +N  YA H C  +      F  CH  + PG YY 
Sbjct: 585  ANAWRVSSTCFAPVHVPVVDPCNINQQNIGYAAH-CDVIHQE--LFAPCHIYISPGLYYQ 641

Query: 656  NCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVS 715
             C  D C C  S  CLC AL+ Y + C   GV +  +R  +    +  C K M YH+  S
Sbjct: 642  LCRHDACKCGSS--CLCNALAHYAYLCGQHGVPID-FRTQISFCAVV-CQKGMLYHHCSS 697

Query: 716  TCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDT-GKCVQASNCPCYHRGSMIPNGE 774
             C  +C SLS  +  CS      +GC CP+G F +DT   CV   +C C++RGS+   GE
Sbjct: 698  FCLHSCISLSSPE-QCSDDC--AEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGE 754

Query: 775  SVHDSGAICTCTHGKLSCIGGQAPAPV--CAAPMVFFDCRNATPG--DTGAGCQKSCHTL 830
             +     +C C++G + C     P+ V  C     +FDCR   P     G  C+ +C  L
Sbjct: 755  LIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANL 814

Query: 831  DM--TCY-SPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTC 887
             M  TC  S  C+ GCVC  G+                                     C
Sbjct: 815  AMNFTCTPSSPCISGCVCAPGV-------------------------------------C 837

Query: 888  DSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVV 947
               M+ CT  PC A C +YGD HY +FDG  Y +  DC+  L+      K +      V+
Sbjct: 838  RRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLI------KSADDSDISVI 891

Query: 948  TENVPCGTTGTTCSKAIKIFLGGFELKLSHG--KVEVIGTDESQEVPYTIRQMGIYLVVD 1005
             +N  C      CSK++ I +G  E+ L+    K +  G     +  Y + + G Y+VV 
Sbjct: 892  AQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTYQLWKAGYYIVVY 951

Query: 1006 -TDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNS 1064
              +  + +LWD+KT+I I + P++K ++ GLCGNFD    ND  T +   V +   FG+S
Sbjct: 952  FPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDS 1011

Query: 1065 WKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDAC 1124
            W L   C        PC A+  +  +A+K+CSIL+   FA+C   ++   + + C  D C
Sbjct: 1012 WALG-QCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTC 1070

Query: 1125 ACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWHY 1178
             C+ GGDCEC CT++AAYA  C + G+ + WR+ ++C L C+YYN EG  E  Y
Sbjct: 1071 NCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDCEYYN-EGLGEGPY 1123



 Score =  228 bits (580), Expect = 6e-59
 Identities = 148/461 (32%), Positives = 218/461 (47%), Gaps = 47/461 (10%)

Query: 823  CQKSCHTLDMTCYSPQ--CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRV 880
            C  +C T +  C      C+ GC CPDGLV D  G CI+ E+CPC  +  +Y  G  I  
Sbjct: 344  CPPTC-TFEKQCLGSNLHCLDGCYCPDGLVMDN-GTCISLENCPCGFHGLAYSVGSKIEQ 401

Query: 881  GCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDST 940
             C  C C   +W CT+  C   C+V GD H+ TFDG+ YSF G C+Y LV      K + 
Sbjct: 402  ECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILV------KGTG 455

Query: 941  QDSFRVVTENVPCGTT-GTTCSKAIKIFL-GGFELKLSHGKVEVIGTDESQEVPYT---- 994
            +D F +  +  PC    G  C ++I + L   F  +++ G+   I T  +Q         
Sbjct: 456  KDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVE 515

Query: 995  IRQMG-IYLVVDTDIGLVLLWD-KKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSR 1052
            I+ +  +++++ T  GL +L+      I+I L+  +K R  GLCG F+    +DF + S 
Sbjct: 516  IQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSG 575

Query: 1053 SVVGDVLEFGNSWKLSPSC--PDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHV 1110
             + G      N+W++S +C  P  +   DPC  N     +A   C ++H   FA CH ++
Sbjct: 576  MIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGYAA-HCDVIHQELFAPCHIYI 634

Query: 1111 EPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTP-SICPLFCDYYN 1169
             P  YY+ C +DAC C S     C C A+A YA  C + G+ + +RT  S C + C    
Sbjct: 635  SPGLYYQLCRHDACKCGSS----CLCNALAHYAYLCGQHGVPIDFRTQISFCAVVC---- 686

Query: 1170 PEGQCEWHYQPCGVPCLRTCRNPRG--DCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVAT 1227
               Q    Y  C   CL +C +      C  D    EGC   CP E   +++    CV  
Sbjct: 687  ---QKGMLYHHCSSFCLHSCISLSSPEQCSDDC--AEGC--NCP-EGKFYEDTLNFCV-- 736

Query: 1228 CPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVEC 1268
               P    RCH  G  Y+PG ++P+      C C+   V+C
Sbjct: 737  ---PIFHCRCHYRGSVYQPGELIPTPSGL--CQCSNGTVKC 772



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 122/499 (24%), Positives = 195/499 (39%), Gaps = 88/499 (17%)

Query: 719  PTCRSLSEGDITCSVGFIPVDGCI--CPKGTFLDD-TGKCVQASNCPCYHRGSMIPNGES 775
            P  ++ S+ +        PV+GC+  CPK   LD+ T KCV   +C       +IP   +
Sbjct: 1287 PCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCI-----PVIPTEPT 1341

Query: 776  VHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGC--QKSCHTLDMT 833
            +                I    P+ +    M+       TP  TG  C  QK     D +
Sbjct: 1342 LMPPAKPTVPMFTVWEMI---TPSDITVFDML-------TP-TTGLECEPQKFDPVYDCS 1390

Query: 834  CYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWR 893
             Y       C+  +  + +    C    + P    +  +R G+ ++V  + C  +   W 
Sbjct: 1391 QYI------CLNMEWQLYNWSLNCPKDVEMP----DCGFR-GRPVQVNSDICCPE---WE 1436

Query: 894  CTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPC 953
            C   PC   C++  +   +TFDG + +      Y LV+    G+       +      P 
Sbjct: 1437 C---PC--RCSMLSELSIITFDGNNAALYSMASYILVR--IPGEIIVAHIEKCSMNQAPS 1489

Query: 954  GTTGTTCSKAI-------KIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDT 1006
            G     C K +       KI +     K+    + V     SQE+  +I   G   V+ T
Sbjct: 1490 GRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQEL--SIEDSGSMYVITT 1547

Query: 1007 DIGLVLLWDKKTSIF-------INLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVL 1059
              GL++ W   T I         NLS   +G +CG+C    D   +D   ++ +++ ++ 
Sbjct: 1548 PAGLIIKWSHLTGIIDIHFGFRFNLSSYTEG-LCGICNEDPD---DDLRMQNGTIITNME 1603

Query: 1060 EFG---NSWKLSPSCPDALA-PKDPCTANPFRKSWAQKQC-SILHGPTFAACHAHVEPAR 1114
            + G    SW++  S    +  P   CT +         QC  +L+   F  CH  V P  
Sbjct: 1604 DIGLFIESWEIEKSFEVTMRRPVRNCTEHDC------SQCIDLLNRRIFIPCHDKVSPED 1657

Query: 1115 YYEAC-VNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQ 1173
            + E   +N     +        C A++AY   C++  +C+ WRTP  C L C    PEG+
Sbjct: 1658 FCEKMWINYTYFWNYE------CDALSAYVALCNKFDICIQWRTPDYCSLSC----PEGK 1707

Query: 1174 CEWHYQPCGVPC-LRTCRN 1191
                YQPC  PC  RTC N
Sbjct: 1708 ---EYQPCVRPCEARTCLN 1723



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 99/436 (22%), Positives = 158/436 (36%), Gaps = 48/436 (11%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPT--LSRVLM 138
            CS        TFDG+      + +Y+     G   E     + +   + AP+  +S +  
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPG---EIIVAHIEKCSMNQAPSGRISGLCF 1497

Query: 139  K-------VDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNH 191
            K       +  +++      V V+   V LPFS   + I+ S S   +    GL++ W+H
Sbjct: 1498 KKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSH 1557

Query: 192  DDSLL---LELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME-FGNLQKMDDPTEQ 247
               ++          ++ T GLCG  N  P     + + T +T ME  G   +  +  + 
Sbjct: 1558 LTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKS 1617

Query: 248  CQDPVPEPPRNCST-GFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSC 306
             +  +  P RNC+      C +LL+ ++F  C   V    + E       +   T   + 
Sbjct: 1618 FEVTMRRPVRNCTEHDCSQCIDLLNRRIFIPCHDKVSPEDFCEKM-----WINYTYFWNY 1672

Query: 307  VCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPC-ADTCSNQ-EHSRAC 364
             C  L+ Y   C       Q WR PD+C   CP   +Y  C  PC A TC NQ  +    
Sbjct: 1673 ECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTS 1731

Query: 365  EDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACV-YNGAAYAPGATYSTDCTNCTCSGGRW 423
              +    C C  GT+L       C+P  +CAC          G  ++     CT     +
Sbjct: 1732 CLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTL----Y 1787

Query: 424  SCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDS 483
             C E                  +G    +  DC    T  C+  A  V+  + +      
Sbjct: 1788 KCLE------------------NGSIIPIEPDCDEEPTPVCEREAEVVMGIIDKWTCCSK 1829

Query: 484  ETCLKSVTLSLDGVQT 499
            E C    TL    + T
Sbjct: 1830 EVCGCDTTLCETSIPT 1845



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 123/527 (23%), Positives = 187/527 (35%), Gaps = 58/527 (11%)

Query: 425  CQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD-- 482
            C E  CP  CS+L      TFDG    ++   SY+L +        ++A + +C +    
Sbjct: 1432 CPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVR---IPGEIIVAHIEKCSMNQAP 1488

Query: 483  ----SETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQ 538
                S  C K + ++   +  ++V + + +V ++ I   LP S+  ++I    + ++I  
Sbjct: 1489 SGRISGLCFKKLNVTTP-IHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVIT- 1546

Query: 539  TSLGLQLN-LQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEAT---AA 594
            T  GL +    L   + +       L   T GLCG  N    DD R  +G +        
Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606

Query: 595  AFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGP--FGRCHAAVKPGT 652
             F  +++       I  SFE      V N    +H CSQ  D      F  CH  V P  
Sbjct: 1607 LFIESWE-------IEKSFEVTMRRPVRN--CTEHDCSQCIDLLNRRIFIPCHDKVSPED 1657

Query: 653  YYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHY 712
            +   C     N     +  C ALS+YV  C    + +       C+    +CP+   Y  
Sbjct: 1658 F---CEKMWINYTYFWNYECDALSAYVALCNKFDICIQWRTPDYCS---LSCPEGKEYQP 1711

Query: 713  HVSTCQP-TC-RSLSEGDITCSVGFIPVDGCICPKGTFL--DDTGKCVQASNCPCYHRGS 768
             V  C+  TC      G  +C       + C+C  GT L    + +C+    C C     
Sbjct: 1712 CVRPCEARTCLNQWFYGHTSC---LNLREDCVCKVGTILHRPHSAQCIPEKECACTDSED 1768

Query: 769  MIPNGESVHDSGAICTCTHGKLSCIGG---------QAPAPVC----AAPMVFFDCRNAT 815
              P       +G I  CT  K    G          + P PVC       M   D     
Sbjct: 1769 Q-PRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCEREAEVVMGIIDKWTCC 1827

Query: 816  PGDTGAGCQKS-CHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRA 874
              +   GC  + C T   TC + Q +     P       +  C   + CP +        
Sbjct: 1828 SKEV-CGCDTTLCETSIPTCTNSQKLIVGHSPLSCCPQYKCECDPLK-CPSISTPECRED 1885

Query: 875  GQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSF 921
               I+V      C S    C  + C     +  DG +LT D  S  F
Sbjct: 1886 QFMIQVRQEEPCCFSPF--CVCESCTKPVPLCHDGEFLTVDLNSTHF 1930



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 34/103 (33%), Positives = 44/103 (42%), Gaps = 9/103 (8%)

Query: 1174 CEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCV---ATCPT 1230
            CEW Y+PC  PC +TC +P     + +  +EGC P CP    I DE  ++CV      P 
Sbjct: 1277 CEWRYEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNM-ILDEVTLKCVYPRDCIPV 1335

Query: 1231 PPLPPRCHVHGKSYRP-----GAVVPSDKNCQSCLCTERGVEC 1268
             P  P      K   P       + PSD      L    G+EC
Sbjct: 1336 IPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLEC 1378



 Score = 34.3 bits (77), Expect = 1.3
 Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 9/57 (15%)

Query: 343  QYHECRSPCADTCSNQEHSRACED-HCVAGC--FCPEGTVLDDIG-----QTGCVPV 391
            +Y  C +PC  TCS+ E + AC+    V GC  +CP+  +LD++         C+PV
Sbjct: 1280 RYEPCATPCFKTCSDPE-ALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPV 1335


>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
            sapiens]
          Length = 3003

 Score =  410 bits (1055), Expect = e-114
 Identities = 363/1368 (26%), Positives = 549/1368 (40%), Gaps = 224/1368 (16%)

Query: 70   RASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQE 127
            +A   A +  VC   G  HY TFDG  +   G C+Y   E C        F+++ +    
Sbjct: 461  KAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHR 520

Query: 128  SAAPT--LSRVLMKVDGVVIQLTKGSV---LVNGHPVLLP--FSQSGVLIQQSSSYTKVE 180
             +     +  V ++     + LT+G V   LV+     LP   S+  + + QS     VE
Sbjct: 521  GSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVE 580

Query: 181  ARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL 238
               GLV+ ++ D  L L L  ++ ++ CGLCG++NG P   + L+ +  L P  +EF + 
Sbjct: 581  LVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA-DDFLTPDGALAPDAVEFASS 639

Query: 239  QKMDDPTEQCQDPVPEPPRNCSTGFGICEE--LLHGQL------FSGCVALVDVGSYLEA 290
             K+DD    C+D        C+ G     E   L G L      F+ C   +D   +LE 
Sbjct: 640  WKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQ 699

Query: 291  CRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP 350
            C  DLC      L   +C  L+ Y++ C   G    DWR P  CP  CP N +Y  C   
Sbjct: 700  CVYDLCVVGGERL--SLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPA 757

Query: 351  CADTCSNQEHSRACEDH-CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
            C  +C+       C    CV GC C  G V        CVP S C C + G   APG   
Sbjct: 758  CPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG---GACVPASSCGCTFQGLQLAPGQEV 814

Query: 410  STD--C-TNCTCSGG--RWSCQE-VPCP-------------------GTCSVLGGAHFST 444
              D  C   CTC+G   + +C++   CP                   GTC   G  H+ +
Sbjct: 815  WADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVS 874

Query: 445  FDGKQYTVHGDCSYVLTKPCDSS----AFTVLAELRRCGLTDSETCLKSVTLSLDGVQTV 500
            FDG+++   G C+Y+L   C  +    AF VL E    G + + +  ++V +   GV+  
Sbjct: 875  FDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRG-SQTVSYTRAVRVEARGVKVA 933

Query: 501  VVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQ 558
            V  +  G+V ++ +   LP  AA+  V +FR     ++ +T  GL +        ++  +
Sbjct: 934  VRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVV-RTDFGLTVTYDW--NARVTAK 990

Query: 559  LAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF--KTQAACPNIRNSFEDP 616
            +        CGLCGNFN   ADD     G   A A AF N++  +T+  C          
Sbjct: 991  VPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPK 1050

Query: 617  CSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALS 676
                V  +  +++ C  L D  GPF  CH+ + P     +C++D C        LC AL+
Sbjct: 1051 LDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALA 1110

Query: 677  SYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITC--SVG 734
            +Y  AC A G  +  WR          CP S   H H   C   C  LS GD+      G
Sbjct: 1111 TYAAACQAAGATVHPWRS------EELCPLSCPPHSHYEACSYGC-PLSCGDLPVPGGCG 1163

Query: 735  FIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIG 794
                +GC+C +G  L     C+  ++C C H+G+  P G++ +                 
Sbjct: 1164 SECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFY----------------- 1205

Query: 795  GQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGE 854
                                     G GC   CH  +                       
Sbjct: 1206 ------------------------PGPGCDSLCHCQE----------------------- 1218

Query: 855  GGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTF 914
            GG ++ E   C  +EA   +G ++  GC                  +TC   GD HY TF
Sbjct: 1219 GGLVSCESSSCGPHEACQPSGGSL--GCVAVGS-------------STCQASGDPHYTTF 1263

Query: 915  DGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELK 974
            DG+ + F G C Y L Q  CG +      F V+ ENV  G    + ++ I + +  F L+
Sbjct: 1264 DGRRFDFMGTCVYVLAQT-CGTRPGLH-RFAVLQENVAWGNGRVSVTRVITVQVANFTLR 1321

Query: 975  LSHGKVEVIGTDESQEVPYTI-------RQMGIYLVVDTDIGLVLLWDKKTSIFINLSPE 1027
            L   + +V       ++P  +        Q G  +V++TD GL + +D    + + +   
Sbjct: 1322 LEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGN 1381

Query: 1028 FKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWK--------LSPS-CP---DAL 1075
            +  ++CGLCGN++    +DF   + S  G+  EFGNSW+        L P+ CP   +  
Sbjct: 1382 YYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDC 1441

Query: 1076 APKDPCTANPFRKSWAQKQCSILHGPT--FAACHAHVEPARYYEACVNDACACDSGGDCE 1133
             P   C     +K   ++ C +L  PT   ++CH  V+P    + C+ D C    GG+  
Sbjct: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLS 1499

Query: 1134 CFCTAVAAYAQACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNP 1192
              C+ + AY  AC   G  V  WRT + CP+ C    P    E     C + C      P
Sbjct: 1500 ILCSNIHAYVSACQAAGGHVEPWRTETFCPMECP---PNSHYELCADTCSLGCSALSAPP 1556

Query: 1193 R------GDCLRD---VWGLEGCYP--KC----------PPEAPIFDEDKMQCVATCPTP 1231
            +        C  D   ++  + C P  +C          P +  + D  + QC       
Sbjct: 1557 QCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKG 1616

Query: 1232 PLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTE--RGVEC----TYKAE----ACVCTYNG 1281
             +   C  H  S +PG V        SC+  +   GV C    T K +     C+  Y  
Sbjct: 1617 MV---CQEH--SCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEA 1671

Query: 1282 QRFHPGDVIYHTTDG-----TGGC--ISARCGANGTIERRVYPCSPTT 1322
              +  GD  YH+ DG      G C  + A  G  G   + + P + TT
Sbjct: 1672 TCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTT 1719



 Score =  358 bits (918), Expect = 4e-98
 Identities = 322/1209 (26%), Positives = 475/1209 (39%), Gaps = 209/1209 (17%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEH-C-GAAYEDFN--IQLRRSQESAAPTLSRV 136
            C  WG  HY +FDG  F F G CNYV +   C G + +         ++Q    P +S V
Sbjct: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732

Query: 137  LMKVDGVV--------IQLTKGSVLVNGHPVLLPFSQSG--VLIQQSSSYTKVEARLGLV 186
             +     +         ++ K  V VNG    LP S +   + + Q +S   + A  GL 
Sbjct: 1733 RVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 1792

Query: 187  LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMD-D 243
            + ++ +  + + L + Y    CGLCG+ +  P   ++  + T     P+  G+ +    D
Sbjct: 1793 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 1852

Query: 244  PT--EQCQDPVPEPPRNCST---GFGICEELLHGQ--LFSGCVALVDVGSYLEACRQDLC 296
            P   ++C+   P  P +      G G C  L  G    F+ C A V   S+ + C  D+C
Sbjct: 1853 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVC 1912

Query: 297  FCE-DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTC 355
                D D+L   C  LA Y   C  AG + +DWR    C   CP N  Y  C  PC  +C
Sbjct: 1913 MGGGDRDIL---CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASC 1969

Query: 356  SNQEH---SRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSK-CACVYNGAAYAPGATYST 411
             +         CE  CV GC C  G VL       CVP++  C C  NG  +  G+ +  
Sbjct: 1970 PSPAPLTTPAVCEGPCVEGCQCDAGFVLS---ADRCVPLNNGCGCWANGTYHEAGSEFWA 2026

Query: 412  D-----------------CTNCTCS---------GGRWSCQEVPCPGTCSVLGGAHFSTF 445
            D                 CT  +C           G+  CQ V     C   G  H+ T 
Sbjct: 2027 DGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVST-AECQAWGDPHYVTL 2085

Query: 446  DGKQYTVHGDCSYVLTKPCD-----SSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTV 500
            DG ++   G C Y+L+ PC      +  FTV       G + + +  +SVTL +      
Sbjct: 2086 DGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLT 2144

Query: 501  VVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLA 560
            +  +   ++ ++ ++  LP    ++     S   ++  T+ GL L       ++L +  A
Sbjct: 2145 LSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA 2204

Query: 561  PKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLS 620
                   CGLCGN+N   ADD + + G       A +     Q     +      PC+  
Sbjct: 2205 --YAASLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPCTPE 2257

Query: 621  VENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVH 680
             +        C  ++  DGP   CH  V P  Y+  C+ D C  +     LC A+++YV 
Sbjct: 2258 QQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVA 2317

Query: 681  ACAAKGVQLGGW-RDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLS--EG-DITCSVGFI 736
            AC A G QLG W R   C      CP    Y     +C  +C SLS  EG +  C     
Sbjct: 2318 ACQAAGAQLGEWRRPDFCP---LQCPAHSHYELCGDSCPVSCPSLSAPEGCESACR---- 2370

Query: 737  PVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIGGQ 796
              +GC+C  G F+     CV    C C H G   P GE                      
Sbjct: 2371 --EGCVCDAG-FVLSGDTCVPVGQCGCLHDGRYYPLGE---------------------- 2405

Query: 797  APAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPG--CVCPDGLVADGE 854
                      VF+          G  C++ C          +C PG    C +G      
Sbjct: 2406 ----------VFY---------PGPECERRC----------ECGPGGHVTCQEGAACGPH 2436

Query: 855  GGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTF 914
              C   +     H             GC  C  +                  G  HY+T 
Sbjct: 2437 EECRLEDGVQACH-----------ATGCGRCLAN------------------GGIHYITL 2467

Query: 915  DGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELK 974
            DG+ Y  +G C Y L Q  C  K   +D F +V E    G       + + + + G  + 
Sbjct: 2468 DGRVYDLHGSCSYVLAQ-VCHPKPGDED-FSIVLEKNAAGDL-----QRLLVTVAGQVVS 2520

Query: 975  LSHGKVEVIGTDESQEVPYTIRQM-----GIYLVVDTDIGLVLLWDKKTSIFINLSPEFK 1029
            L+ G+ +V    E+  +P  + ++     G  +V+ T  GL LL+D    + +++   F+
Sbjct: 2521 LAQGQ-QVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 2579

Query: 1030 GRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL---SPSCPDALAPK--DPCTAN 1084
            GR+CGLCGNF+    +DF   + S    V  FG +W+    S  C +   P+    C A 
Sbjct: 2580 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 2639

Query: 1085 PFRKSWAQKQCSILHGP--TFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAY 1142
                  + + C  L  P   FA C A + P+ Y+  CV D CA    GD    C ++AAY
Sbjct: 2640 ETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAY 2697

Query: 1143 AQACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVW 1201
              AC   G+ V  WRT S CPL C  ++       HY      C RTC   +G C   + 
Sbjct: 2698 TAACQAAGVAVKPWRTDSFCPLHCPAHS-------HYS----ICTRTC---QGSCAA-LS 2742

Query: 1202 GLEGCYPKC 1210
            GL GC  +C
Sbjct: 2743 GLTGCTTRC 2751



 Score =  343 bits (880), Expect = 1e-93
 Identities = 350/1348 (25%), Positives = 526/1348 (39%), Gaps = 239/1348 (17%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAA---YEDFNIQLRRSQESAAPTLSRVL 137
            C   G  HY TFDG  F F G C YV ++ CG     +    +Q   +  +   +++RV+
Sbjct: 1252 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 1311

Query: 138  -MKVDGVVIQLTKGS--VLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLVLMWNHD 192
             ++V    ++L +    V VNG  + LP   +   +   Q  S   +E   GL + ++  
Sbjct: 1312 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLV 1371

Query: 193  DSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKL-TPMEFGNLQKMDDPTEQCQDP 251
              + + +   Y  + CGLCG++NG P       + ++     EFGN  +   P   C  P
Sbjct: 1372 YYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPP 1431

Query: 252  VPEPP--RNCSTGFGICEEL--------LHGQL------FSGCVALVDVGSYLEACRQDL 295
             P PP   +C        EL          G L       S C  LVD    L+ C  DL
Sbjct: 1432 TPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL 1491

Query: 296  CFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTC 355
            C       LS +C  +  Y   C  AGG  + WR   FCP +CP N  Y  C   C+  C
Sbjct: 1492 CLGGGN--LSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549

Query: 356  SNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTD-CT 414
            S       C+D C  GC C  G + +  GQ  CVP+ +C C +NG  Y P  T   D C 
Sbjct: 1550 SALSAPPQCQDGCAEGCQCDSGFLYN--GQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCR 1606

Query: 415  N-CTCSGGRWS-CQEVPC-PG--------------------------------------- 432
              CTC  G+   CQE  C PG                                       
Sbjct: 1607 QQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCL 1666

Query: 433  -----TCSVLGGAHFSTFDGKQYTVHGDCSYVL-TKPCDS------SAFTVLAELRRCGL 480
                 TC + G  H+ +FDG+++   G C+YVL T  C        + FTV  + +  G 
Sbjct: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG- 1725

Query: 481  TDSETCLKSVTLSLDGVQTVVVIKASGE--VFLNQIYTQLPISAAN--VTIFRPSTFFII 536
              + + ++ VT++  G    +     G+  V +N + T LP+S A+  +++ + ++  ++
Sbjct: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALL 1785

Query: 537  AQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAF 596
                 GLQ++       ++ + L     G  CGLCGN +    +D    +G +  +   +
Sbjct: 1786 V-ADFGLQVSYDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIW 1842

Query: 597  FNTFKTQAACPNIRNSFEDPCSLSVEN--EKY-AQHWCSQL-TDADGPFGRCHAAVKPGT 652
              +++     P   +     C    E+  E+Y    +C  L +   GPF  CHA V P +
Sbjct: 1843 GGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPES 1902

Query: 653  YYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHY 712
            ++  C+ D C      D LC AL+SYV AC A GV +  WR  V  +   TCP++  Y  
Sbjct: 1903 FFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITCPENSHYEV 1960

Query: 713  HVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASN-CPCYHRGSMIP 771
                C  +C S +            V+GC C  G F+    +CV  +N C C+  G+   
Sbjct: 1961 CGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHE 2019

Query: 772  NGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLD 831
             G      G   TC+                        CR    G +            
Sbjct: 2020 AGSEFWADG---TCSQW----------------------CRCGPGGGS------------ 2042

Query: 832  MTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRM 891
            + C    C  G VC  GL+  G+ GC                                  
Sbjct: 2043 LVCTPASCGLGEVC--GLLPSGQHGC---------------------------------- 2066

Query: 892  WRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENV 951
                     A C  +GD HY+T DG  + F G CEY L+   C G     ++F V   N 
Sbjct: 2067 ----QPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY-LLSAPCHGPPLGAENFTVTVANE 2121

Query: 952  PCGTTGTTCSKAIKIFLGGFELKLS---HGKVEVIGTDESQEVPYTIRQM------GIYL 1002
              G+   + ++++ + +    L LS     K++V G   +  +P+ +  +      G  +
Sbjct: 2122 HRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVA--LPFQLDSLLHAHLSGADV 2179

Query: 1003 VVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFG 1062
            VV T  GL L +D  + + + +   +   +CGLCGN++    +D         G      
Sbjct: 2180 VVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG------ 2233

Query: 1063 NSWKL--SPSCPDALAP--KDPCTANPFRKSWAQKQCSIL---HGPTFAACHAHVEPARY 1115
              W++  +  C + ++     PCT            C ++    GP  A CH  V PA+Y
Sbjct: 2234 --WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGP-LAPCHGLVPPAQY 2290

Query: 1116 YEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCDYYNPEGQC 1174
            ++ C+ DAC     G     C AVA Y  AC   G  +  WR P  CPL C  ++     
Sbjct: 2291 FQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHS----- 2343

Query: 1175 EWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLP 1234
              HY+ CG  C  +C +        +   EGC   C  E  + D   +    TC  P   
Sbjct: 2344 --HYELCGDSCPVSCPS--------LSAPEGCESAC-REGCVCDAGFVLSGDTC-VPVGQ 2391

Query: 1235 PRCHVHGKSYRPGAVVPSDKNCQ-SCLCTERGVECTYKAEACVCTYNGQRFHPGDVIYHT 1293
              C   G+ Y  G V      C+  C C   G     +  AC   +   R   G    H 
Sbjct: 2392 CGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAAC-GPHEECRLEDGVQACHA 2450

Query: 1294 TDGTGGCISARCGANG-----TIERRVY 1316
            T    GC   RC ANG     T++ RVY
Sbjct: 2451 T----GC--GRCLANGGIHYITLDGRVY 2472



 Score =  283 bits (725), Expect = 9e-76
 Identities = 227/780 (29%), Positives = 321/780 (41%), Gaps = 92/780 (11%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA---AYEDFNIQLRRSQESAAPTLSRVL 137
            C  WG  HY T DG  F F G C Y+ S  C       E+F + +           S+ +
Sbjct: 2074 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-----SQAV 2128

Query: 138  MKVDGVVIQLTKGSVL----------VNGHPVLLPFSQSGVL-IQQSSSYTKVEARLGLV 186
                 V +Q+   S+           V+G  V LPF    +L    S +   V    GL 
Sbjct: 2129 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLS 2188

Query: 187  LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDD-PT 245
            L ++ D  + L +   YA   CGLCG++N  P   +L +   K    + G  Q   +  +
Sbjct: 2189 LAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQGCGECVS 2247

Query: 246  EQCQDPVPEPPRNCSTGFGICEEL--LHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303
            + C  P     +    G   C  +    G L + C  LV    Y + C  D C  +    
Sbjct: 2248 KPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP- 2305

Query: 304  LSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363
               +C  +A Y   C  AG    +WR PDFCP +CP +  Y  C   C  +C +      
Sbjct: 2306 -GGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 2364

Query: 364  CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTCS- 419
            CE  C  GC C  G VL   G T CVPV +C C+++G  Y  G  +    +C   C C  
Sbjct: 2365 CESACREGCVCDAGFVLS--GDT-CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGP 2421

Query: 420  GGRWSCQE-VPCP-------------------GTCSVLGGAHFSTFDGKQYTVHGDCSYV 459
            GG  +CQE   C                    G C   GG H+ T DG+ Y +HG CSYV
Sbjct: 2422 GGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYV 2481

Query: 460  LTKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIY 515
            L + C        F+++ E    G  D +  L +V         VV +    +V ++   
Sbjct: 2482 LAQVCHPKPGDEDFSIVLEKNAAG--DLQRLLVTVA------GQVVSLAQGQQVTVDGEA 2533

Query: 516  TQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFN 575
              LP++   V +       ++ QT+ GL+L         L M +    RG+ CGLCGNFN
Sbjct: 2534 VALPVAVGRVRVTAEGRNMVL-QTTKGLRLLFD--GDAHLLMSIPSPFRGRLCGLCGNFN 2590

Query: 576  SIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCS-------LSVENEKY-A 627
               +DDF   +G    +AA+   TF      P       + C        L+ E   Y +
Sbjct: 2591 GNWSDDFVLPNG----SAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYES 2646

Query: 628  QHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGV 687
               C QL +  GPF  C A + P  Y+  C++D C  +  +  LC +L++Y  AC A GV
Sbjct: 2647 NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGV 2706

Query: 688  QLGGWR-DGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKG 746
             +  WR D  C      CP    Y     TCQ +C +LS G   C+      +GC C   
Sbjct: 2707 AVKPWRTDSFCP---LHCPAHSHYSICTRTCQGSCAALS-GLTGCTTRCF--EGCEC-DD 2759

Query: 747  TFLDDTGKCVQASNCPCYHRGSMIPNGESV--HDSGAICTCTHGK-LSC-IGGQAPAPVC 802
             FL   G C+   +C C H G  +P   S+   D    C+C+    L+C   G  P  VC
Sbjct: 2760 RFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVC 2819



 Score =  185 bits (469), Expect = 4e-46
 Identities = 153/557 (27%), Positives = 248/557 (44%), Gaps = 61/557 (10%)

Query: 69   VRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQ 126
            V+A +    GR C   G  HY T DG V+   G C+YV ++ C      EDF+I L   +
Sbjct: 2445 VQACHATGCGR-CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVL---E 2500

Query: 127  ESAAPTLSRVLMKVDGVVIQLTKGS-VLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGL 185
            ++AA  L R+L+ V G V+ L +G  V V+G  V LP +   V +        ++   GL
Sbjct: 2501 KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGL 2560

Query: 186  VLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME-FGNLQKMDDP 244
             L+++ D  LL+ + + +  + CGLCG+FNG      +L + +  + +E FG   +    
Sbjct: 2561 RLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGS 2620

Query: 245  TEQCQDPVPEPPRNCSTGFG----------ICEELLHGQ-LFSGCVALVDVGSYLEACRQ 293
            ++ C +     P+ C                C +L + Q  F+ C A++    Y   C  
Sbjct: 2621 SKGCGEGC--GPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVY 2678

Query: 294  DLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD 353
            DLC  +     + +C +LA Y+  C  AG   + WR   FCP  CP +  Y  C   C  
Sbjct: 2679 DLCAQKGDK--AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQG 2736

Query: 354  TCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP--GATYST 411
            +C+       C   C  GC C +  +L    Q  C+PV  C C +NG  Y P   +  ++
Sbjct: 2737 SCAALSGLTGCTTRCFEGCECDDRFLL---SQGVCIPVQDCGCTHNG-RYLPVNSSLLTS 2792

Query: 412  DCT-NCTCSGGR-WSCQEVPCP------------------GTCSVLGGAHFSTFDGKQYT 451
            DC+  C+CS     +CQ   CP                  G C +  GA+ +TFDG +  
Sbjct: 2793 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 2852

Query: 452  VHGDCSYVLTKPCDSSA-----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKAS 506
                  Y L+  C         + V+AE++ C    +E   +      DG+ T+   K  
Sbjct: 2853 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICH-GKTEAVGQVHIFFQDGMVTLTPNKG- 2910

Query: 507  GEVFLNQIYTQLPI-SAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRG 565
              V++N +   LP    A+V++ R     ++ +   G+Q  + L    ++ + ++    G
Sbjct: 2911 --VWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQ--VWLGANGKVAVIVSNDHAG 2966

Query: 566  QTCGLCGNFNSIQADDF 582
            + CG CGNF+  Q +D+
Sbjct: 2967 KLCGACGNFDGDQTNDW 2983



 Score =  151 bits (381), Expect = 7e-36
 Identities = 128/453 (28%), Positives = 186/453 (41%), Gaps = 82/453 (18%)

Query: 400 GAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPG--TCSVLGGA----------------- 440
           G A A G   + DC     S    SC+ + C     C V+GG                  
Sbjct: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDP 478

Query: 441 HFSTFDGKQYTVHGDCSYVLTKPCDSS----AFTVLAELRRCGLTDSETCLKSVTLSLDG 496
           H++TFDG++Y + G CSY + + C       AF+V A+    G         S  +S  G
Sbjct: 479 HYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRG---------SRRVSYVG 529

Query: 497 VQTVVVIKAS--------GEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLN 546
           + TV     S        G V ++   ++LP+S +   + +++     ++       +L 
Sbjct: 530 LVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVV-------ELV 582

Query: 547 LQLVPTM----QLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT 602
             LV T     QL + L  + + Q CGLCGN+N   ADDF T  G +   A  F +++K 
Sbjct: 583 FGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKL 642

Query: 603 QAACPNIRNSFEDPCSLSVENEKYAQHW-----CSQLTDADGPFGRCHAAVKPGTYYSNC 657
                   +  ++ C      +  AQH+     C  LT  DGPF  CH  + P  +   C
Sbjct: 643 DDGDYLCEDGCQNNCPACTPGQ--AQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQC 700

Query: 658 MFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTC 717
           ++D C        LC  LS+Y  AC   G+ +G WR          CP S   +     C
Sbjct: 701 VYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS------PANCPLSCPANSRYELC 754

Query: 718 QPTCRSLSEG---DITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGE 774
            P C +   G      CS G   V+GC+C  G F+   G CV AS+C C  +G  +  G+
Sbjct: 755 GPACPTSCNGAAAPSNCS-GRPCVEGCVCLPG-FVASGGACVPASSCGCTFQGLQLAPGQ 812

Query: 775 SVHDSGAI---CTC---TH-----GKLSCIGGQ 796
            V         CTC   TH      K SC  G+
Sbjct: 813 EVWADELCQRRCTCNGATHQVTCRDKQSCPAGE 845



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 60/263 (22%), Positives = 95/263 (36%), Gaps = 51/263 (19%)

Query: 823  CQKSCHTLD-MTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVG 881
            CQ SC  L  +T  + +C  GC C D  +   +G CI  +DC C HN        ++   
Sbjct: 2734 CQGSCAALSGLTGCTTRCFEGCECDDRFLLS-QGVCIPVQDCGCTHNGRYLPVNSSLLTS 2792

Query: 882  --CNTCTCDSRMW----------------RCTDDPCLAT---CAVYGDGHYLTFDGQSYS 920
                 C+C S                   +     C AT   C +    +  TFDG   +
Sbjct: 2793 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 2852

Query: 921  FNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPC----------------GTTGTTCSKAI 964
                  Y L  + C G  +T   +RVV E   C                G    T +K +
Sbjct: 2853 TTSPGVYEL-SSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGV 2911

Query: 965  KIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINL 1024
              ++ G  + L   K+  +    + +    +RQ           G+ +       + + +
Sbjct: 2912 --WVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKA---------GVQVWLGANGKVAVIV 2960

Query: 1025 SPEFKGRVCGLCGNFDDIAVNDF 1047
            S +  G++CG CGNFD    ND+
Sbjct: 2961 SNDHAGKLCGACGNFDGDQTNDW 2983


>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
          Length = 5405

 Score =  410 bits (1055), Expect = e-114
 Identities = 363/1368 (26%), Positives = 549/1368 (40%), Gaps = 224/1368 (16%)

Query: 70   RASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQE 127
            +A   A +  VC   G  HY TFDG  +   G C+Y   E C        F+++ +    
Sbjct: 461  KAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHR 520

Query: 128  SAAPT--LSRVLMKVDGVVIQLTKGSV---LVNGHPVLLP--FSQSGVLIQQSSSYTKVE 180
             +     +  V ++     + LT+G V   LV+     LP   S+  + + QS     VE
Sbjct: 521  GSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVE 580

Query: 181  ARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL 238
               GLV+ ++ D  L L L  ++ ++ CGLCG++NG P   + L+ +  L P  +EF + 
Sbjct: 581  LVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA-DDFLTPDGALAPDAVEFASS 639

Query: 239  QKMDDPTEQCQDPVPEPPRNCSTGFGICEE--LLHGQL------FSGCVALVDVGSYLEA 290
             K+DD    C+D        C+ G     E   L G L      F+ C   +D   +LE 
Sbjct: 640  WKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQ 699

Query: 291  CRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP 350
            C  DLC      L   +C  L+ Y++ C   G    DWR P  CP  CP N +Y  C   
Sbjct: 700  CVYDLCVVGGERL--SLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPA 757

Query: 351  CADTCSNQEHSRACEDH-CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
            C  +C+       C    CV GC C  G V        CVP S C C + G   APG   
Sbjct: 758  CPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG---GACVPASSCGCTFQGLQLAPGQEV 814

Query: 410  STD--C-TNCTCSGG--RWSCQE-VPCP-------------------GTCSVLGGAHFST 444
              D  C   CTC+G   + +C++   CP                   GTC   G  H+ +
Sbjct: 815  WADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVS 874

Query: 445  FDGKQYTVHGDCSYVLTKPCDSS----AFTVLAELRRCGLTDSETCLKSVTLSLDGVQTV 500
            FDG+++   G C+Y+L   C  +    AF VL E    G + + +  ++V +   GV+  
Sbjct: 875  FDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRG-SQTVSYTRAVRVEARGVKVA 933

Query: 501  VVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQ 558
            V  +  G+V ++ +   LP  AA+  V +FR     ++ +T  GL +        ++  +
Sbjct: 934  VRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVV-RTDFGLTVTYDW--NARVTAK 990

Query: 559  LAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF--KTQAACPNIRNSFEDP 616
            +        CGLCGNFN   ADD     G   A A AF N++  +T+  C          
Sbjct: 991  VPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPK 1050

Query: 617  CSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALS 676
                V  +  +++ C  L D  GPF  CH+ + P     +C++D C        LC AL+
Sbjct: 1051 LDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALA 1110

Query: 677  SYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITC--SVG 734
            +Y  AC A G  +  WR          CP S   H H   C   C  LS GD+      G
Sbjct: 1111 TYAAACQAAGATVHPWRS------EELCPLSCPPHSHYEACSYGC-PLSCGDLPVPGGCG 1163

Query: 735  FIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIG 794
                +GC+C +G  L     C+  ++C C H+G+  P G++ +                 
Sbjct: 1164 SECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFY----------------- 1205

Query: 795  GQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGE 854
                                     G GC   CH  +                       
Sbjct: 1206 ------------------------PGPGCDSLCHCQE----------------------- 1218

Query: 855  GGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTF 914
            GG ++ E   C  +EA   +G ++  GC                  +TC   GD HY TF
Sbjct: 1219 GGLVSCESSSCGPHEACQPSGGSL--GCVAVGS-------------STCQASGDPHYTTF 1263

Query: 915  DGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELK 974
            DG+ + F G C Y L Q  CG +      F V+ ENV  G    + ++ I + +  F L+
Sbjct: 1264 DGRRFDFMGTCVYVLAQT-CGTRPGLH-RFAVLQENVAWGNGRVSVTRVITVQVANFTLR 1321

Query: 975  LSHGKVEVIGTDESQEVPYTI-------RQMGIYLVVDTDIGLVLLWDKKTSIFINLSPE 1027
            L   + +V       ++P  +        Q G  +V++TD GL + +D    + + +   
Sbjct: 1322 LEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGN 1381

Query: 1028 FKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWK--------LSPS-CP---DAL 1075
            +  ++CGLCGN++    +DF   + S  G+  EFGNSW+        L P+ CP   +  
Sbjct: 1382 YYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDC 1441

Query: 1076 APKDPCTANPFRKSWAQKQCSILHGPT--FAACHAHVEPARYYEACVNDACACDSGGDCE 1133
             P   C     +K   ++ C +L  PT   ++CH  V+P    + C+ D C    GG+  
Sbjct: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLS 1499

Query: 1134 CFCTAVAAYAQACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNP 1192
              C+ + AY  AC   G  V  WRT + CP+ C    P    E     C + C      P
Sbjct: 1500 ILCSNIHAYVSACQAAGGHVEPWRTETFCPMECP---PNSHYELCADTCSLGCSALSAPP 1556

Query: 1193 R------GDCLRD---VWGLEGCYP--KC----------PPEAPIFDEDKMQCVATCPTP 1231
            +        C  D   ++  + C P  +C          P +  + D  + QC       
Sbjct: 1557 QCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKG 1616

Query: 1232 PLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTE--RGVEC----TYKAE----ACVCTYNG 1281
             +   C  H  S +PG V        SC+  +   GV C    T K +     C+  Y  
Sbjct: 1617 MV---CQEH--SCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEA 1671

Query: 1282 QRFHPGDVIYHTTDG-----TGGC--ISARCGANGTIERRVYPCSPTT 1322
              +  GD  YH+ DG      G C  + A  G  G   + + P + TT
Sbjct: 1672 TCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTT 1719



 Score =  377 bits (969), Expect = e-104
 Identities = 328/1190 (27%), Positives = 476/1190 (40%), Gaps = 168/1190 (14%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA---AYEDFNIQLRRSQESAAPTLSRVL 137
            C  WG  HY T DG  F F G C Y+ S  C       E+F + +           S+ +
Sbjct: 3273 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-----SQAV 3327

Query: 138  MKVDGVVIQLTKGSVL----------VNGHPVLLPFSQSGVL-IQQSSSYTKVEARLGLV 186
                 V +Q+   S+           V+G  V LPF    +L    S +   V    GL 
Sbjct: 3328 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLS 3387

Query: 187  LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDD-PT 245
            L ++ D  + L +   YA   CGLCG++N  P   +L +   K    + G  Q   +  +
Sbjct: 3388 LAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQGCGECVS 3446

Query: 246  EQCQDPVPEPPRNCSTGFGICEEL--LHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303
            + C  P     +    G   C  +    G L + C  LV    Y + C  D C  +    
Sbjct: 3447 KPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP- 3504

Query: 304  LSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363
               +C  +A Y   C  AG   ++WR PDFCP +CP +  Y  C   C  +C +      
Sbjct: 3505 -GGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 3563

Query: 364  CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTC-S 419
            CE  C  GC C  G VL   G T CVPV +C C+++   Y  G T+     C + C C  
Sbjct: 3564 CESACREGCVCDAGFVLS--GDT-CVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCRE 3620

Query: 420  GGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVHGDCSYVL 460
            GG  SC+   C                     TC   G  H++TFDG ++   G C YVL
Sbjct: 3621 GGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVL 3680

Query: 461  TKPCDS----SAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYT 516
             + C +      F VL E    G     +  + +T+ +    T+ + +   +V +N +  
Sbjct: 3681 AQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRVITVQVANF-TLRLEQRQWKVTVNGVDM 3738

Query: 517  QLPISAANVTIFRPSTF--FIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNF 574
            +LP+  AN  I R S     ++ +T  GL++   LV  ++  + +        CGLCGN+
Sbjct: 3739 KLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVR--VTVPGNYYQLMCGLCGNY 3795

Query: 575  NSIQADDFRTLSGVVEATAAAFFNTFK---------TQAACP--NIRNSFEDPCSLSVEN 623
            N    DDF+  +G     A  F N+++             CP  +      D C   +E 
Sbjct: 3796 NGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEK 3855

Query: 624  EKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACA 683
            +   + +C  L+   GP   CH  V P     +C+FD C    +   LC+ + +YV AC 
Sbjct: 3856 KYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQ 3915

Query: 684  AKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCIC 743
            A G  +  WR+     PM  CP++  Y     TC   C +LS   + C  G    +GC C
Sbjct: 3916 AAGGHVEPWRNETFC-PM-ECPQNSHYELCADTCSLGCSALS-APLQCPDGC--AEGCQC 3970

Query: 744  PKGTFLDDTGKCVQASNCPCYHRGSMIPNGESV--HDSGAICTCTHGKLSCIGGQAPAPV 801
              G FL +   CV    C CYH G      ++V   +    CTC  GK+           
Sbjct: 3971 DSG-FLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKV----------- 4018

Query: 802  CAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVC-PDGLVADGEGGCITA 860
                                          + C    C PG VC P G    G   C+T 
Sbjct: 4019 ------------------------------VVCQEHSCKPGQVCQPSG----GILSCVTK 4044

Query: 861  EDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYS 920
            + C           G T R    TC        C  +   ATC ++GD HY +FDG+ + 
Sbjct: 4045 DPC----------HGVTCRPQ-ETCKEQGGQGVCLPN-YEATCWLWGDPHYHSFDGRKFD 4092

Query: 921  FNGDCEYTLVQNHCGGKDSTQ--DSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSH- 977
            F G C Y L    C G  STQ    F V T+N   G    +  + + +   G  + +   
Sbjct: 4093 FQGTCNYVLATTGCPGV-STQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKD 4151

Query: 978  --GKVEVIGTDESQEVP-----YTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKG 1030
              GKV V G   +  V       ++ Q     ++  D GL + +D    + + L   + G
Sbjct: 4152 EIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHG 4211

Query: 1031 RVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL---SPSCPDALAPKDP-CTANPF 1086
             VCGLCGN D    ND    + ++   +  +G SW+     P C D      P C  +  
Sbjct: 4212 AVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRL 4271

Query: 1087 RKSWAQKQCSILH---GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYA 1143
             +      C  L    G  F  CHAHV P  +++ CV D C    GGD +  C A+A+Y 
Sbjct: 4272 EQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRDILCKALASYV 4329

Query: 1144 QACHEVGLCV-SWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNP 1192
             AC   G+ +  WR    C + C    PE     HY+ CG PC  +C +P
Sbjct: 4330 AACQAAGVVIEDWRAQVGCEITC----PENS---HYEVCGPPCPASCPSP 4372



 Score =  360 bits (925), Expect = 6e-99
 Identities = 325/1207 (26%), Positives = 476/1207 (39%), Gaps = 207/1207 (17%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEH-C-GAAYEDFN--IQLRRSQESAAPTLSRV 136
            C  WG  HY +FDG  F F G CNYV +   C G + +         ++Q    P +S V
Sbjct: 4075 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 4134

Query: 137  ---LMKVDGVVIQLTK---GSVLVNGHPVLLPFSQSG--VLIQQSSSYTKVEARLGLVLM 188
                +   G  I + K   G V VNG    LP S +   + + Q +S   + A  GL + 
Sbjct: 4135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 4194

Query: 189  WNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMD-DPT 245
            ++ +  + + L + Y    CGLCG+ +  P   ++  + T     P+  G+ +    DP 
Sbjct: 4195 YDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL 4254

Query: 246  --EQCQDPVPEPPRNCST---GFGICEELLHGQ--LFSGCVALVDVGSYLEACRQDLCFC 298
              ++C+   P  P +      G G C  L  G    F+ C A V   S+ + C  D+C  
Sbjct: 4255 CWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMG 4314

Query: 299  E-DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSN 357
              D D+L   C  LA Y   C  AG + +DWR    C   CP N  Y  C  PC  +C +
Sbjct: 4315 GGDRDIL---CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 4371

Query: 358  QEH---SRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSK-CACVYNGAAYAPGATYSTD- 412
                     CE  CV GC C  G VL       CVP++  C C  NG  +  G+ +  D 
Sbjct: 4372 PAPLTTPAVCEGPCVEGCQCDAGFVLS---ADRCVPLNNGCGCWANGTYHEAGSEFWADG 4428

Query: 413  ----------------CTNCTCS---------GGRWSCQEVPCPGTCSVLGGAHFSTFDG 447
                            CT  +C           G+  CQ V     C   G  H+ T DG
Sbjct: 4429 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVST-AECQAWGDPHYVTLDG 4487

Query: 448  KQYTVHGDCSYVLTKPCD-----SSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVV 502
             ++   G C Y+L+ PC      +  FTV       G + + +  +SVTL +      + 
Sbjct: 4488 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLTLS 4546

Query: 503  IKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPK 562
             +   ++ ++ ++  LP    ++     S   ++  T+ GL L       ++L +  A  
Sbjct: 4547 ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA-- 4604

Query: 563  LRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVE 622
                 CGLCGN+N   ADD + + G       A +     Q     +      PC+   +
Sbjct: 4605 YAASLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPCTPEQQ 4659

Query: 623  NEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHAC 682
                    C  ++  DGP   CH  V P  Y+  C+ D C  +     LC A+++YV AC
Sbjct: 4660 ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAAC 4719

Query: 683  AAKGVQLGGW-RDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLS--EG-DITCSVGFIPV 738
             A G QLG W R   C      CP    Y     +C  +C SLS  EG +  C       
Sbjct: 4720 QAAGAQLGEWRRPDFCP---LQCPAHSHYELCGDSCPVSCPSLSAPEGCESACR------ 4770

Query: 739  DGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIGGQAP 798
            +GC+C  G F+     CV    C C H G   P GE                        
Sbjct: 4771 EGCVCDAG-FVLSGDTCVPVGQCGCLHDGRYYPLGE------------------------ 4805

Query: 799  APVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPG--CVCPDGLVADGEGG 856
                    VF+          G  C++ C          +C PG    C +G        
Sbjct: 4806 --------VFY---------PGPECERRC----------ECGPGGHVTCQEGAACGPHEE 4838

Query: 857  CITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDG 916
            C   +     H             GC  C  +                  G  HY+T DG
Sbjct: 4839 CRLEDGVQACH-----------ATGCGRCLAN------------------GGIHYITLDG 4869

Query: 917  QSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLS 976
            + Y  +G C Y L Q  C  K   +D F +V E    G       + + + + G  + L+
Sbjct: 4870 RVYDLHGSCSYVLAQ-VCHPKPGDED-FSIVLEKNAAGDL-----QRLLVTVAGQVVSLA 4922

Query: 977  HGKVEVIGTDESQEVPYTIRQM-----GIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGR 1031
             G+ +V    E+  +P  + ++     G  +V+ T  GL LL+D    + +++   F+GR
Sbjct: 4923 QGQ-QVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGR 4981

Query: 1032 VCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL---SPSCPDALAPK--DPCTANPF 1086
            +CGLCGNF+    +DF   + S    V  FG +W+    S  C +   P+    C A   
Sbjct: 4982 LCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEET 5041

Query: 1087 RKSWAQKQCSILHGP--TFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQ 1144
                + + C  L  P   FA C A + P+ Y+  CV D CA    GD    C ++AAY  
Sbjct: 5042 APYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTA 5099

Query: 1145 ACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGL 1203
            AC   G+ V  WRT S CPL C  ++       HY      C RTC   +G C   + GL
Sbjct: 5100 ACQAAGVAVKPWRTDSFCPLHCPAHS-------HYS----ICTRTC---QGSCAA-LSGL 5144

Query: 1204 EGCYPKC 1210
             GC  +C
Sbjct: 5145 TGCTTRC 5151



 Score =  344 bits (882), Expect = 6e-94
 Identities = 350/1351 (25%), Positives = 524/1351 (38%), Gaps = 247/1351 (18%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAA---YEDFNIQLRRSQESAAPTLSRVL 137
            C   G  HY TFDG  F F G C YV ++ CG     +    +Q   +  +   +++RV+
Sbjct: 3654 CQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 3713

Query: 138  -MKVDGVVIQLTKGS--VLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLVLMWNHD 192
             ++V    ++L +    V VNG  + LP   +   +   Q  S   +E   GL + ++  
Sbjct: 3714 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLV 3773

Query: 193  DSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKL-TPMEFGNLQKMDDPTEQCQDP 251
              + + +   Y    CGLCG++NG P       + ++     EFGN  +   P   C   
Sbjct: 3774 YYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCL-- 3831

Query: 252  VPEPPRNCSTGFGIC---------------EELLHGQL------FSGCVALVDVGSYLEA 290
               PP  C  G   C               +E   G L       S C  LVD    L+ 
Sbjct: 3832 ---PPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 3888

Query: 291  CRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP 350
            C  DLC       LS +C  +  Y   C  AGG  + WR   FCP +CP N  Y  C   
Sbjct: 3889 CIFDLCLGGGN--LSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADT 3946

Query: 351  CADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYS 410
            C+  CS       C D C  GC C  G + +  GQ  CVP+ +C C +NG  Y P  T  
Sbjct: 3947 CSLGCSALSAPLQCPDGCAEGCQCDSGFLYN--GQA-CVPIQQCGCYHNGVYYEPEQTVL 4003

Query: 411  TD-CTN-CTC---------------------SGGRWSC-QEVPCPG-------------- 432
             D C   CTC                     SGG  SC  + PC G              
Sbjct: 4004 IDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGG 4063

Query: 433  ----------TCSVLGGAHFSTFDGKQYTVHGDCSYVL-TKPCDS------SAFTVLAEL 475
                      TC + G  H+ +FDG+++   G C+YVL T  C        + FTV  + 
Sbjct: 4064 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 4123

Query: 476  RRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTF 533
            +  G   + + ++ VT++  G    +     G+V +N + T LP+S A+  +++ + ++ 
Sbjct: 4124 QNRG-NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASK 4182

Query: 534  FIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATA 593
             ++     GLQ++       ++ + L     G  CGLCGN +    +D    +G +  + 
Sbjct: 4183 ALLV-ADFGLQVSYDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSI 4239

Query: 594  AAFFNTFKTQAACPNIRNSFEDPCSLSVEN--EKY-AQHWCSQLTD-ADGPFGRCHAAVK 649
              +  +++     P   +     C    E+  E+Y    +C  L+    GPF  CHA V 
Sbjct: 4240 PIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVP 4299

Query: 650  PGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMT 709
            P +++  C+ D C      D LC AL+SYV AC A GV +  WR  V  +   TCP++  
Sbjct: 4300 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITCPENSH 4357

Query: 710  YHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASN-CPCYHRGS 768
            Y      C  +C S +            V+GC C  G F+    +CV  +N C C+  G+
Sbjct: 4358 YEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGT 4416

Query: 769  MIPNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCH 828
                G      G   TC+                        CR    G +         
Sbjct: 4417 YHEAGSEFWADG---TCSQW----------------------CRCGPGGGS--------- 4442

Query: 829  TLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCD 888
               + C    C  G VC  GL+  G+ GC                               
Sbjct: 4443 ---LVCTPASCGLGEVC--GLLPSGQHGC------------------------------- 4466

Query: 889  SRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVT 948
                        A C  +GD HY+T DG  + F G CEY L+   C G     ++F V  
Sbjct: 4467 -------QPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY-LLSAPCHGPPLGAENFTVTV 4518

Query: 949  ENVPCGTTGTTCSKAIKIFLGGFELKLS---HGKVEVIGTDESQEVPYTIRQM------G 999
             N   G+   + ++++ + +    L LS     K++V G   +  +P+ +  +      G
Sbjct: 4519 ANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVA--LPFQLDSLLHAHLSG 4576

Query: 1000 IYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVL 1059
              +VV T  GL L +D  + + + +   +   +CGLCGN++    +D         G   
Sbjct: 4577 ADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--- 4633

Query: 1060 EFGNSWKL--SPSCPDALAP--KDPCTANPFRKSWAQKQCSIL---HGPTFAACHAHVEP 1112
                 W++  +  C + ++     PCT            C ++    GP  A CH  V P
Sbjct: 4634 -----WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGP-LAPCHGLVPP 4687

Query: 1113 ARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCDYYNPE 1171
            A+Y++ C+ DAC     G     C AVA Y  AC   G  +  WR P  CPL C  ++  
Sbjct: 4688 AQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHS-- 4743

Query: 1172 GQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTP 1231
                 HY+ CG  C  +C +        +   EGC   C  E  + D   +    TC  P
Sbjct: 4744 -----HYELCGDSCPVSCPS--------LSAPEGCESAC-REGCVCDAGFVLSGDTC-VP 4788

Query: 1232 PLPPRCHVHGKSYRPGAVVPSDKNCQ-SCLCTERGVECTYKAEACVCTYNGQRFHPGDVI 1290
                 C   G+ Y  G V      C+  C C   G     +  AC   +   R   G   
Sbjct: 4789 VGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAAC-GPHEECRLEDGVQA 4847

Query: 1291 YHTTDGTGGCISARCGANG-----TIERRVY 1316
             H T    GC   RC ANG     T++ RVY
Sbjct: 4848 CHAT----GC--GRCLANGGIHYITLDGRVY 4872



 Score =  343 bits (881), Expect = 7e-94
 Identities = 337/1295 (26%), Positives = 509/1295 (39%), Gaps = 228/1295 (17%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAA---YEDFNIQLRRSQESAAPTLSRVL 137
            C   G  HY TFDG  F F G C YV ++ CG     +    +Q   +  +   +++RV+
Sbjct: 1252 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 1311

Query: 138  -MKVDGVVIQLTKGS--VLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLVLMWNHD 192
             ++V    ++L +    V VNG  + LP   +   +   Q  S   +E   GL + ++  
Sbjct: 1312 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLV 1371

Query: 193  DSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKL-TPMEFGNLQKMDDPTEQCQDP 251
              + + +   Y  + CGLCG++NG P       + ++     EFGN  +   P   C  P
Sbjct: 1372 YYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPP 1431

Query: 252  VPEPP--RNCSTGFGICEEL--------LHGQL------FSGCVALVDVGSYLEACRQDL 295
             P PP   +C        EL          G L       S C  LVD    L+ C  DL
Sbjct: 1432 TPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL 1491

Query: 296  CFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTC 355
            C       LS +C  +  Y   C  AGG  + WR   FCP +CP N  Y  C   C+  C
Sbjct: 1492 CLGGGN--LSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549

Query: 356  SNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTD-CT 414
            S       C+D C  GC C  G + +  GQ  CVP+ +C C +NG  Y P  T   D C 
Sbjct: 1550 SALSAPPQCQDGCAEGCQCDSGFLYN--GQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCR 1606

Query: 415  N-CTCSGGRWS-CQEVPC-PG--------------------------------------- 432
              CTC  G+   CQE  C PG                                       
Sbjct: 1607 QQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCL 1666

Query: 433  -----TCSVLGGAHFSTFDGKQYTVHGDCSYVL-TKPCDS------SAFTVLAELRRCGL 480
                 TC + G  H+ +FDG+++   G C+YVL T  C        + FTV  + +  G 
Sbjct: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG- 1725

Query: 481  TDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQ 538
              + + ++ VT++  G    +     G+V +N + T LP+S A+  +++ + ++  ++  
Sbjct: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV- 1784

Query: 539  TSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFN 598
               GLQ++       ++ + L     G  CGLCGN +    +D    +G +  +   +  
Sbjct: 1785 ADFGLQVSYDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGG 1842

Query: 599  TFKTQAACPNIRNSFEDPCSLSVEN--EKY-AQHWCSQLTDADG-PFGRCHAAVKPGTYY 654
            +++     P   +     C    E+  E+Y    +C  L    G PF  CHA V P +++
Sbjct: 1843 SWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFF 1902

Query: 655  SNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHV 714
              C+ D C      D LC AL+SYV AC A GV +  WR  V  +   TCP++  Y    
Sbjct: 1903 KGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITCPENSHYEVCG 1960

Query: 715  STCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASN-CPCYHRGSMIPNG 773
            S C  +C S +            V+GC C  G F+    +CV  +N C C+  G+    G
Sbjct: 1961 SPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAG 2019

Query: 774  ESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMT 833
                  G   TC+                        CR    G +            + 
Sbjct: 2020 SEFWADG---TCSQW----------------------CRCGPGGGS------------LV 2042

Query: 834  CYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWR 893
            C    C  G VC  GL+  G+ GC                                    
Sbjct: 2043 CTPASCGLGEVC--GLLPSGQHGC------------------------------------ 2064

Query: 894  CTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPC 953
                   A C  +GD HY+T DG  ++F G CEY L+   C G     ++F V   N   
Sbjct: 2065 --QPVSTAECQAWGDPHYVTLDGHRFNFQGTCEY-LLSAPCHGPPLGAENFTVTVANEHR 2121

Query: 954  GTTGTTCSKAIKIFLGGFELKLS---HGKVEVIGTDESQEVPYTIRQM------GIYLVV 1004
            G+   + ++++ + +    L LS     K++V G   +  +P+ +  +      G  +VV
Sbjct: 2122 GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT--LPFQLDSLLHAHLSGADVVV 2179

Query: 1005 DTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNS 1064
             T  GL L +D  + + + +   + G +CGLCGN++    +D         G        
Sbjct: 2180 TTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG-------- 2231

Query: 1065 WKL--SPSCPDALAP--KDPCTANPFRKSWAQKQCSIL---HGPTFAACHAHVEPARYYE 1117
            W++  +  C + ++     PCT            C ++    GP  A CH  V PA+Y++
Sbjct: 2232 WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGP-LAPCHGLVPPAQYFQ 2290

Query: 1118 ACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCDYYNPEGQCEW 1176
             C+ DAC     G     C AVA Y  AC   G  +  WR P  CP  C  ++       
Sbjct: 2291 GCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHS------- 2341

Query: 1177 HYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPR 1236
            HY+ CG  C  +C +        +   EGC   C  E  + D   +    TC   P+   
Sbjct: 2342 HYELCGDSCPGSCPS--------LSAPEGCESAC-REGCVCDAGFVLSGDTC--VPVGQC 2390

Query: 1237 CHVHGKSYRP-GAVVPSDKNCQS-CLCTERG-VEC 1268
              +H   Y P G        C S C C E G V C
Sbjct: 2391 GCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSC 2425



 Score =  338 bits (867), Expect = 3e-92
 Identities = 337/1300 (25%), Positives = 506/1300 (38%), Gaps = 238/1300 (18%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAA---YEDFNIQLRRSQESAAPTLSRVL 137
            C   G  HY TFDG  F F G C YV ++ CG     +    +Q   +  +   +++RV+
Sbjct: 2453 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 2512

Query: 138  -MKVDGVVIQLTKGS--VLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLVLMWNHD 192
             ++V    ++L +    V VNG  + LP   +   +   Q  S   +E   GL + ++  
Sbjct: 2513 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLV 2572

Query: 193  DSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKL-TPMEFGNLQKMDDPTEQCQDP 251
              + + +   Y    CGLCG++NG P       + ++     EFGN  +   P   C   
Sbjct: 2573 YYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCL-- 2630

Query: 252  VPEPPRNCSTGFGIC---------------EELLHGQL------FSGCVALVDVGSYLEA 290
               PP  C  G   C               +E   G L       S C  LVD    L+ 
Sbjct: 2631 ---PPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 2687

Query: 291  CRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP 350
            C  DLC       LS +C  +  Y   C  AGG  + WR   FCP +CP N  Y  C   
Sbjct: 2688 CIFDLCLGGGN--LSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADT 2745

Query: 351  CADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYS 410
            C+  CS       C D C  GC C  G + +  GQ  CVP+ +C C +NGA Y P  T  
Sbjct: 2746 CSLGCSALSAPLQCPDGCAEGCQCDSGFLYN--GQA-CVPIQQCGCYHNGAYYEPEQTVL 2802

Query: 411  TD-CTN-CTC---------------------SGGRWSC-QEVPCPG-------------- 432
             D C   CTC                     SGG  SC  + PC G              
Sbjct: 2803 IDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGG 2862

Query: 433  ----------TCSVLGGAHFSTFDGKQYTVHGDCSYVL-TKPCDS------SAFTVLAEL 475
                      TC + G  H+ +FDG+++   G C+YVL T  C        + FTV  + 
Sbjct: 2863 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 2922

Query: 476  RRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTF 533
            +  G   + + ++ VT++  G    +     G+V +N + T LP+S A+  +++ + ++ 
Sbjct: 2923 QNRG-NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASK 2981

Query: 534  FIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATA 593
             ++     GLQ++       ++ + L     G  CGLCGN +    +D    +G +  + 
Sbjct: 2982 ALLV-ADFGLQVSYDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSI 3038

Query: 594  AAFFNTFKTQAACPNIRNSFEDPCSLSVEN--EKY-AQHWCSQLTDADG-PFGRCHAAVK 649
              +  +++     P   +     C    E+  E+Y    +C  L    G PF  CHA V 
Sbjct: 3039 PIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 3098

Query: 650  PGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMT 709
            P +++  C+ D C      D LC AL+SYV AC A GV +  WR  V  +   TCP++  
Sbjct: 3099 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITCPENSH 3156

Query: 710  YHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASN-CPCYHRGS 768
            Y      C  +C S +            V+GC C  G F+    +CV  +N C C+  G+
Sbjct: 3157 YEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGT 3215

Query: 769  MIPNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCH 828
                G      G   TC+                        CR    G +         
Sbjct: 3216 YHEAGSEFWADG---TCSQW----------------------CRCGPGGGS--------- 3241

Query: 829  TLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCD 888
               + C    C  G VC  GL+  G+ GC                               
Sbjct: 3242 ---LVCTPASCGLGEVC--GLLPSGQHGC------------------------------- 3265

Query: 889  SRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVT 948
                        A C  +GD HY+T DG  + F G CEY L+   C G     ++F V  
Sbjct: 3266 -------QPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY-LLSAPCHGPPLGAENFTVTV 3317

Query: 949  ENVPCGTTGTTCSKAIKIFLGGFELKLS---HGKVEVIGTDESQEVPYTIRQM------G 999
             N   G+   + ++++ + +    L LS     K++V G   +  +P+ +  +      G
Sbjct: 3318 ANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT--LPFQLDSLLHAHLSG 3375

Query: 1000 IYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVL 1059
              +VV T  GL L +D  + + + +   + G +CGLCGN++    +D         G   
Sbjct: 3376 ADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--- 3432

Query: 1060 EFGNSWKL--SPSCPDALAP--KDPCTANPFRKSWAQKQCSIL---HGPTFAACHAHVEP 1112
                 W++  +  C + ++     PCT            C ++    GP  A CH  V P
Sbjct: 3433 -----WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGP-LAPCHGLVPP 3486

Query: 1113 ARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCDYYNPE 1171
            A+Y++ C+ DAC     G     C AVA Y  AC   G  +  WR P  CP  C  ++  
Sbjct: 3487 AQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHS-- 3542

Query: 1172 GQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTP 1231
                 HY+ CG  C  +C +        +   EGC   C  E  + D   +    TC   
Sbjct: 3543 -----HYELCGDSCPGSCPS--------LSAPEGCESAC-REGCVCDAGFVLSGDTC--V 3586

Query: 1232 PLPPRCHVHGKSYRP-GAVVPSDKNCQS-CLCTERG-VEC 1268
            P+     +H   Y P G        C S C C E G V C
Sbjct: 3587 PVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSC 3626



 Score =  283 bits (725), Expect = 9e-76
 Identities = 227/780 (29%), Positives = 321/780 (41%), Gaps = 92/780 (11%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA---AYEDFNIQLRRSQESAAPTLSRVL 137
            C  WG  HY T DG  F F G C Y+ S  C       E+F + +           S+ +
Sbjct: 4474 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-----SQAV 4528

Query: 138  MKVDGVVIQLTKGSVL----------VNGHPVLLPFSQSGVL-IQQSSSYTKVEARLGLV 186
                 V +Q+   S+           V+G  V LPF    +L    S +   V    GL 
Sbjct: 4529 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLS 4588

Query: 187  LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDD-PT 245
            L ++ D  + L +   YA   CGLCG++N  P   +L +   K    + G  Q   +  +
Sbjct: 4589 LAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQGCGECVS 4647

Query: 246  EQCQDPVPEPPRNCSTGFGICEEL--LHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303
            + C  P     +    G   C  +    G L + C  LV    Y + C  D C  +    
Sbjct: 4648 KPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP- 4705

Query: 304  LSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363
               +C  +A Y   C  AG    +WR PDFCP +CP +  Y  C   C  +C +      
Sbjct: 4706 -GGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 4764

Query: 364  CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTCS- 419
            CE  C  GC C  G VL   G T CVPV +C C+++G  Y  G  +    +C   C C  
Sbjct: 4765 CESACREGCVCDAGFVLS--GDT-CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGP 4821

Query: 420  GGRWSCQE-VPCP-------------------GTCSVLGGAHFSTFDGKQYTVHGDCSYV 459
            GG  +CQE   C                    G C   GG H+ T DG+ Y +HG CSYV
Sbjct: 4822 GGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYV 4881

Query: 460  LTKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIY 515
            L + C        F+++ E    G  D +  L +V         VV +    +V ++   
Sbjct: 4882 LAQVCHPKPGDEDFSIVLEKNAAG--DLQRLLVTVA------GQVVSLAQGQQVTVDGEA 4933

Query: 516  TQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFN 575
              LP++   V +       ++ QT+ GL+L         L M +    RG+ CGLCGNFN
Sbjct: 4934 VALPVAVGRVRVTAEGRNMVL-QTTKGLRLLFD--GDAHLLMSIPSPFRGRLCGLCGNFN 4990

Query: 576  SIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCS-------LSVENEKY-A 627
               +DDF   +G    +AA+   TF      P       + C        L+ E   Y +
Sbjct: 4991 GNWSDDFVLPNG----SAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYES 5046

Query: 628  QHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGV 687
               C QL +  GPF  C A + P  Y+  C++D C  +  +  LC +L++Y  AC A GV
Sbjct: 5047 NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGV 5106

Query: 688  QLGGWR-DGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKG 746
             +  WR D  C      CP    Y     TCQ +C +LS G   C+      +GC C   
Sbjct: 5107 AVKPWRTDSFCP---LHCPAHSHYSICTRTCQGSCAALS-GLTGCTTRCF--EGCEC-DD 5159

Query: 747  TFLDDTGKCVQASNCPCYHRGSMIPNGESV--HDSGAICTCTHGK-LSC-IGGQAPAPVC 802
             FL   G C+   +C C H G  +P   S+   D    C+C+    L+C   G  P  VC
Sbjct: 5160 RFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVC 5219



 Score =  185 bits (469), Expect = 4e-46
 Identities = 153/557 (27%), Positives = 248/557 (44%), Gaps = 61/557 (10%)

Query: 69   VRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQ 126
            V+A +    GR C   G  HY T DG V+   G C+YV ++ C      EDF+I L   +
Sbjct: 4845 VQACHATGCGR-CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVL---E 4900

Query: 127  ESAAPTLSRVLMKVDGVVIQLTKGS-VLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGL 185
            ++AA  L R+L+ V G V+ L +G  V V+G  V LP +   V +        ++   GL
Sbjct: 4901 KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGL 4960

Query: 186  VLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME-FGNLQKMDDP 244
             L+++ D  LL+ + + +  + CGLCG+FNG      +L + +  + +E FG   +    
Sbjct: 4961 RLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGS 5020

Query: 245  TEQCQDPVPEPPRNCSTGFG----------ICEELLHGQ-LFSGCVALVDVGSYLEACRQ 293
            ++ C +     P+ C                C +L + Q  F+ C A++    Y   C  
Sbjct: 5021 SKGCGEGC--GPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVY 5078

Query: 294  DLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD 353
            DLC  +     + +C +LA Y+  C  AG   + WR   FCP  CP +  Y  C   C  
Sbjct: 5079 DLCAQKGDK--AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQG 5136

Query: 354  TCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP--GATYST 411
            +C+       C   C  GC C +  +L    Q  C+PV  C C +NG  Y P   +  ++
Sbjct: 5137 SCAALSGLTGCTTRCFEGCECDDRFLL---SQGVCIPVQDCGCTHNG-RYLPVNSSLLTS 5192

Query: 412  DCT-NCTCSGGR-WSCQEVPCP------------------GTCSVLGGAHFSTFDGKQYT 451
            DC+  C+CS     +CQ   CP                  G C +  GA+ +TFDG +  
Sbjct: 5193 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 5252

Query: 452  VHGDCSYVLTKPCDSSA-----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKAS 506
                  Y L+  C         + V+AE++ C    +E   +      DG+ T+   K  
Sbjct: 5253 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICH-GKTEAVGQVHIFFQDGMVTLTPNKG- 5310

Query: 507  GEVFLNQIYTQLPI-SAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRG 565
              V++N +   LP    A+V++ R     ++ +   G+Q  + L    ++ + ++    G
Sbjct: 5311 --VWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQ--VWLGANGKVAVIVSNDHAG 5366

Query: 566  QTCGLCGNFNSIQADDF 582
            + CG CGNF+  Q +D+
Sbjct: 5367 KLCGACGNFDGDQTNDW 5383



 Score =  178 bits (452), Expect = 4e-44
 Identities = 167/596 (28%), Positives = 244/596 (40%), Gaps = 115/596 (19%)

Query: 820  GAGCQKSCHTLDMT--CYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQT 877
            G  C  SC +L     C S  C  GCVC  G V  G+  C+    C C+H++  Y  GQT
Sbjct: 3548 GDSCPGSCPSLSAPEGCESA-CREGCVCDAGFVLSGDT-CVPVGQCGCLHDDRYYPLGQT 3605

Query: 878  IRVGCNTCTCDSRMWRCTD------DP-----------------CLA----TCAVYGDGH 910
               G     CDS + RC +      +P                 C+A    TC   GD H
Sbjct: 3606 FYPGPG---CDS-LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPH 3661

Query: 911  YLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGG 970
            Y TFDG  + F G C Y L Q  CG +      F V+ ENV  G    + ++ I + +  
Sbjct: 3662 YTTFDGHRFDFMGTCVYVLAQT-CGTRPGLH-RFAVLQENVAWGNGRVSVTRVITVQVAN 3719

Query: 971  FELKLSHGKVEVIGTDESQEVPYTIR-------QMGIYLVVDTDIGLVLLWDKKTSIFIN 1023
            F L+L   + +V       ++P  +        Q G  +V++TD GL + +D    + + 
Sbjct: 3720 FTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVT 3779

Query: 1024 LSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWK---------LSPSCPDA 1074
            +   +   +CGLCGN++    +DF   + S  G+  EFGNSW+           P+CP  
Sbjct: 3780 VPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPG 3839

Query: 1075 LA---PKDPCTANPFRKSWAQKQCSILHGPT--FAACHAHVEPARYYEACVNDACACDSG 1129
             A   P D C     +K   ++ C +L  PT   ++CH  V+P    + C+ D C    G
Sbjct: 3840 SAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GG 3897

Query: 1130 GDCECFCTAVAAYAQACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRT 1188
            G+    C+ + AY  AC   G  V  WR  + CP+ C    P+     HY+ C   C   
Sbjct: 3898 GNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMEC----PQNS---HYELCADTCSLG 3950

Query: 1189 C-------RNPRG---DCLRD---VWGLEGCYP--KC----------PPEAPIFDEDKMQ 1223
            C       + P G    C  D   ++  + C P  +C          P +  + D  + Q
Sbjct: 3951 CSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQ 4010

Query: 1224 CVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTE--RGVEC----TYKAE---- 1273
            C  TC    +   C  H  S +PG V        SC+  +   GV C    T K +    
Sbjct: 4011 C--TCHVGKVVV-CQEH--SCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQG 4065

Query: 1274 ACVCTYNGQRFHPGDVIYHTTDG-----TGGC--ISARCGANGTIERRVYPCSPTT 1322
             C+  Y    +  GD  YH+ DG      G C  + A  G  G   + + P + TT
Sbjct: 4066 VCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTT 4121



 Score =  176 bits (446), Expect = 2e-43
 Identities = 165/596 (27%), Positives = 245/596 (41%), Gaps = 115/596 (19%)

Query: 820  GAGCQKSCHTLDMT--CYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQT 877
            G  C  SC +L     C S  C  GCVC  G V  G+  C+    C C+H++  Y  GQT
Sbjct: 2347 GDSCPGSCPSLSAPEGCESA-CREGCVCDAGFVLSGDT-CVPVGQCGCLHDDRYYPLGQT 2404

Query: 878  IRVGCNTCTCDSRMWRCTD------DP-----------------CLA----TCAVYGDGH 910
               G     CDS + RC +      +P                 C+A    TC   GD H
Sbjct: 2405 FYPGPG---CDS-LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPH 2460

Query: 911  YLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGG 970
            Y TFDG+ + F G C Y L Q  CG +      F V+ ENV  G    + ++ I + +  
Sbjct: 2461 YTTFDGRRFDFMGTCVYVLAQT-CGTRPGLH-RFAVLQENVAWGNGRVSVTRVITVQVAN 2518

Query: 971  FELKLSHGKVEVIGTDESQEVPYTIR-------QMGIYLVVDTDIGLVLLWDKKTSIFIN 1023
            F L+L   + +V       ++P  +        Q G  +V++TD GL + +D    + + 
Sbjct: 2519 FTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVT 2578

Query: 1024 LSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWK---------LSPSCP-- 1072
            +   +   +CGLCGN++    +DF   + S  G+  EFGNSW+           P+CP  
Sbjct: 2579 VPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPG 2638

Query: 1073 -DALAPKDPCTANPFRKSWAQKQCSILHGPT--FAACHAHVEPARYYEACVNDACACDSG 1129
             +   P + C     +K   ++ C +L  PT   ++CH  V+P    + C+ D C    G
Sbjct: 2639 SEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GG 2696

Query: 1130 GDCECFCTAVAAYAQACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRT 1188
            G+    C+ + AY  AC   G  V  WR  + CP+ C    P+     HY+ C   C   
Sbjct: 2697 GNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMEC----PQNS---HYELCADTCSLG 2749

Query: 1189 C-------RNPRG---DCLRD---VWGLEGCYP--KC----------PPEAPIFDEDKMQ 1223
            C       + P G    C  D   ++  + C P  +C          P +  + D  + Q
Sbjct: 2750 CSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQ 2809

Query: 1224 CVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTE--RGVEC----TYKAE---- 1273
            C  TC    +   C  H  S +PG V        SC+  +   GV C    T K +    
Sbjct: 2810 C--TCHVGKVVV-CQEH--SCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQG 2864

Query: 1274 ACVCTYNGQRFHPGDVIYHTTDG-----TGGC--ISARCGANGTIERRVYPCSPTT 1322
             C+  Y    +  GD  YH+ DG      G C  + A  G  G   + + P + TT
Sbjct: 2865 VCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTT 2920



 Score =  151 bits (381), Expect = 7e-36
 Identities = 128/453 (28%), Positives = 186/453 (41%), Gaps = 82/453 (18%)

Query: 400 GAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPG--TCSVLGGA----------------- 440
           G A A G   + DC     S    SC+ + C     C V+GG                  
Sbjct: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDP 478

Query: 441 HFSTFDGKQYTVHGDCSYVLTKPCDSS----AFTVLAELRRCGLTDSETCLKSVTLSLDG 496
           H++TFDG++Y + G CSY + + C       AF+V A+    G         S  +S  G
Sbjct: 479 HYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRG---------SRRVSYVG 529

Query: 497 VQTVVVIKAS--------GEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLN 546
           + TV     S        G V ++   ++LP+S +   + +++     ++       +L 
Sbjct: 530 LVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVV-------ELV 582

Query: 547 LQLVPTM----QLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT 602
             LV T     QL + L  + + Q CGLCGN+N   ADDF T  G +   A  F +++K 
Sbjct: 583 FGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKL 642

Query: 603 QAACPNIRNSFEDPCSLSVENEKYAQHW-----CSQLTDADGPFGRCHAAVKPGTYYSNC 657
                   +  ++ C      +  AQH+     C  LT  DGPF  CH  + P  +   C
Sbjct: 643 DDGDYLCEDGCQNNCPACTPGQ--AQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQC 700

Query: 658 MFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTC 717
           ++D C        LC  LS+Y  AC   G+ +G WR          CP S   +     C
Sbjct: 701 VYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS------PANCPLSCPANSRYELC 754

Query: 718 QPTCRSLSEG---DITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGE 774
            P C +   G      CS G   V+GC+C  G F+   G CV AS+C C  +G  +  G+
Sbjct: 755 GPACPTSCNGAAAPSNCS-GRPCVEGCVCLPG-FVASGGACVPASSCGCTFQGLQLAPGQ 812

Query: 775 SVHDSGAI---CTC---TH-----GKLSCIGGQ 796
            V         CTC   TH      K SC  G+
Sbjct: 813 EVWADELCQRRCTCNGATHQVTCRDKQSCPAGE 845



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 60/263 (22%), Positives = 95/263 (36%), Gaps = 51/263 (19%)

Query: 823  CQKSCHTLD-MTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVG 881
            CQ SC  L  +T  + +C  GC C D  +   +G CI  +DC C HN        ++   
Sbjct: 5134 CQGSCAALSGLTGCTTRCFEGCECDDRFLLS-QGVCIPVQDCGCTHNGRYLPVNSSLLTS 5192

Query: 882  --CNTCTCDSRMW----------------RCTDDPCLAT---CAVYGDGHYLTFDGQSYS 920
                 C+C S                   +     C AT   C +    +  TFDG   +
Sbjct: 5193 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 5252

Query: 921  FNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPC----------------GTTGTTCSKAI 964
                  Y L  + C G  +T   +RVV E   C                G    T +K +
Sbjct: 5253 TTSPGVYEL-SSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGV 5311

Query: 965  KIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINL 1024
              ++ G  + L   K+  +    + +    +RQ           G+ +       + + +
Sbjct: 5312 --WVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKA---------GVQVWLGANGKVAVIV 5360

Query: 1025 SPEFKGRVCGLCGNFDDIAVNDF 1047
            S +  G++CG CGNFD    ND+
Sbjct: 5361 SNDHAGKLCGACGNFDGDQTNDW 5383


>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding protein
            [Homo sapiens]
          Length = 1403

 Score =  360 bits (924), Expect = 8e-99
 Identities = 323/1207 (26%), Positives = 476/1207 (39%), Gaps = 207/1207 (17%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEH--CGAAYEDFN--IQLRRSQESAAPTLSRV 136
            C  WG  HY +FDG  F F G CNYV +     G + +         +++    P +S V
Sbjct: 75   CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYV 134

Query: 137  ---LMKVDGVVIQLTK---GSVLVNGHPVLLPFSQSG--VLIQQSSSYTKVEARLGLVLM 188
                +   G  I + K   G V VNG    LP S +   + + Q +S   + A  GL + 
Sbjct: 135  RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 194

Query: 189  WNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMD-DPT 245
            ++ +  + + L + Y    CGLCG+ +  P   ++  + T     P+  G+ +    DP 
Sbjct: 195  YDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL 254

Query: 246  --EQCQDPVPEPPRNCST---GFGICEELLHGQ--LFSGCVALVDVGSYLEACRQDLCFC 298
              ++C+   P  P +      G G C  L  G    F+ C A V   S+ + C  D+C  
Sbjct: 255  CWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMG 314

Query: 299  E-DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSN 357
              D D+L   C  LA Y   C  AG + +DWR    C   CP N  Y  C  PC  +C +
Sbjct: 315  GGDHDIL---CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 371

Query: 358  QEH---SRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSK-CACVYNGAAYAPGATYSTD- 412
                     CE  CV GC C  G VL       CVP++  C C  NG  +  G+ +  D 
Sbjct: 372  PAPLTTPAVCEGPCVEGCQCDAGFVLS---ADRCVPLNNGCGCWANGTYHEAGSEFWADG 428

Query: 413  ----------------CTNCTCS---------GGRWSCQEVPCPGTCSVLGGAHFSTFDG 447
                            CT  +C           G+  CQ V     C   G  H+ T DG
Sbjct: 429  TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVST-AECQAWGDPHYVTLDG 487

Query: 448  KQYTVHGDCSYVLTKPCD-----SSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVV 502
             ++   G C Y+L+ PC      +  FTV       G + + +  +SVTL +      + 
Sbjct: 488  HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLTLS 546

Query: 503  IKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPK 562
             +   ++ ++ ++  LP    ++     S   ++  T+ GL L       ++L +  A  
Sbjct: 547  ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA-- 604

Query: 563  LRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVE 622
                 CGLCGN+N   ADD + + G       A +     Q     +      PC+   +
Sbjct: 605  YAASLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPCTPEQQ 659

Query: 623  NEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHAC 682
                    C  ++  DGP   CH  V P  Y+  C+ D C  +     LC A+++YV AC
Sbjct: 660  ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAAC 719

Query: 683  AAKGVQLGGW-RDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLS--EG-DITCSVGFIPV 738
             A G QLG W R   C      CP    Y     +C  +C SLS  EG +  C       
Sbjct: 720  QAAGAQLGEWRRPDFCP---LQCPAHSHYELCGDSCPVSCPSLSAPEGCESACR------ 770

Query: 739  DGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIGGQAP 798
            +GC+C  G F+     CV    C C H G   P GE                        
Sbjct: 771  EGCVCDAG-FVLSGDTCVPVGQCGCLHDGRYYPLGE------------------------ 805

Query: 799  APVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPG--CVCPDGLVADGEGG 856
                    VF+          G  C++ C          +C PG    C +G        
Sbjct: 806  --------VFY---------PGPECERRC----------ECGPGGHVTCQEGAACGPHEE 838

Query: 857  CITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDG 916
            C   +     H             GC  C  +                  G  HY+T DG
Sbjct: 839  CRLEDGVQACH-----------ATGCGRCLAN------------------GGIHYITLDG 869

Query: 917  QSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLS 976
            + Y  +G C Y L Q  C  K   +D F +V E    G       + + + + G  + L+
Sbjct: 870  RVYDLHGSCSYVLAQ-VCHPKPGDED-FSIVLEKNAAGDL-----QRLLVTVAGQVVSLA 922

Query: 977  HGKVEVIGTDESQEVPYTIRQM-----GIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGR 1031
             G+ +V    E+  +P  + ++     G  +V+ T  GL LL+D    + +++   F+GR
Sbjct: 923  QGQ-QVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGR 981

Query: 1032 VCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL---SPSCPDALAPK--DPCTANPF 1086
            +CGLCGNF+    +DF   + S    V  FG +W++   S  C +   P+    C A   
Sbjct: 982  LCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEET 1041

Query: 1087 RKSWAQKQCSILHGP--TFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQ 1144
                + + C  L  P   FA C A + P+ Y+  CV D CA    GD    C ++AAY  
Sbjct: 1042 APYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTA 1099

Query: 1145 ACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGL 1203
            AC   G+ V  WRT S CPL C  ++       HY      C RTC   +G C   + GL
Sbjct: 1100 ACQAAGVAVKPWRTDSFCPLHCPAHS-------HYS----ICTRTC---QGSCAA-LSGL 1144

Query: 1204 EGCYPKC 1210
             GC  +C
Sbjct: 1145 TGCTTRC 1151



 Score =  283 bits (724), Expect = 1e-75
 Identities = 227/780 (29%), Positives = 321/780 (41%), Gaps = 92/780 (11%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA---AYEDFNIQLRRSQESAAPTLSRVL 137
            C  WG  HY T DG  F F G C Y+ S  C       E+F + +           S+ +
Sbjct: 474  CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-----SQAV 528

Query: 138  MKVDGVVIQLTKGSVL----------VNGHPVLLPFSQSGVL-IQQSSSYTKVEARLGLV 186
                 V +Q+   S+           V+G  V LPF    +L    S +   V    GL 
Sbjct: 529  SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLS 588

Query: 187  LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDD-PT 245
            L ++ D  + L +   YA   CGLCG++N  P   +L +   K    + G  Q   +  +
Sbjct: 589  LAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQGCGECVS 647

Query: 246  EQCQDPVPEPPRNCSTGFGICEEL--LHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303
            + C  P     +    G   C  +    G L + C  LV    Y + C  D C  +    
Sbjct: 648  KPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP- 705

Query: 304  LSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363
               +C  +A Y   C  AG    +WR PDFCP +CP +  Y  C   C  +C +      
Sbjct: 706  -GGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764

Query: 364  CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTCS- 419
            CE  C  GC C  G VL   G T CVPV +C C+++G  Y  G  +    +C   C C  
Sbjct: 765  CESACREGCVCDAGFVLS--GDT-CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGP 821

Query: 420  GGRWSCQE-VPCP-------------------GTCSVLGGAHFSTFDGKQYTVHGDCSYV 459
            GG  +CQE   C                    G C   GG H+ T DG+ Y +HG CSYV
Sbjct: 822  GGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYV 881

Query: 460  LTKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIY 515
            L + C        F+++ E    G  D +  L +V         VV +    +V ++   
Sbjct: 882  LAQVCHPKPGDEDFSIVLEKNAAG--DLQRLLVTVA------GQVVSLAQGQQVTVDGEA 933

Query: 516  TQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFN 575
              LP++   V +       ++ QT+ GL+L         L M +    RG+ CGLCGNFN
Sbjct: 934  VALPVAVGRVRVTAEGRNMVL-QTTKGLRLLFD--GDAHLLMSIPSPFRGRLCGLCGNFN 990

Query: 576  SIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCS-------LSVENEKY-A 627
               +DDF   +G    +AA+   TF      P       + C        L+ E   Y +
Sbjct: 991  GNWSDDFVLPNG----SAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYES 1046

Query: 628  QHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGV 687
               C QL +  GPF  C A + P  Y+  C++D C  +  +  LC +L++Y  AC A GV
Sbjct: 1047 NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGV 1106

Query: 688  QLGGWR-DGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKG 746
             +  WR D  C      CP    Y     TCQ +C +LS G   C+      +GC C   
Sbjct: 1107 AVKPWRTDSFCP---LHCPAHSHYSICTRTCQGSCAALS-GLTGCTTRCF--EGCEC-DD 1159

Query: 747  TFLDDTGKCVQASNCPCYHRGSMIPNGESV--HDSGAICTCTHGK-LSC-IGGQAPAPVC 802
             FL   G C+   +C C H G  +P   S+   D    C+C+    L+C   G  P  VC
Sbjct: 1160 RFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVC 1219



 Score =  226 bits (576), Expect = 2e-58
 Identities = 248/996 (24%), Positives = 382/996 (38%), Gaps = 176/996 (17%)

Query: 368  CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAY-------APGATYSTDCT---NCT 417
            C   C  P+      I  T  V +   A +YNG          +P   +   C     C 
Sbjct: 6    CGLACSNPQ------IPGTDWVDMEGAAMLYNGQPLKVLLPLLSPDPCHGVTCRPQETCK 59

Query: 418  CSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVL-TKPC------DSSAFT 470
              GG+  C       TC + G  H+ +FDG+++   G C+YVL T  C        + FT
Sbjct: 60   EQGGQGVCLP-NYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFT 118

Query: 471  VLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAAN--VTIF 528
            V  +    G   + + ++ VT++  G    +     G+V +N + T LP+S A+  +++ 
Sbjct: 119  VTTKNENRG-NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVA 177

Query: 529  RPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGV 588
            + ++  ++     GLQ++       ++ + L     G  CGLCGN +    +D    +G 
Sbjct: 178  QGASKALLV-ADFGLQVSYDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT 234

Query: 589  VEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVEN--EKY-AQHWCSQLT-DADGPFGRC 644
            +  +   +  +++     P   +     C    E+  E+Y    +C  L     GPF  C
Sbjct: 235  LAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTC 294

Query: 645  HAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTC 704
            HA V P +++  C+ D C      D LC AL+SYV AC A GV +  WR  V  +   TC
Sbjct: 295  HAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITC 352

Query: 705  PKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASN-CPC 763
            P++  Y      C  +C S +            V+GC C  G F+    +CV  +N C C
Sbjct: 353  PENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGC 411

Query: 764  YHRGSMIPNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGC 823
            +  G+    G      G   TC+                        CR    G +    
Sbjct: 412  WANGTYHEAGSEFWADG---TCSQW----------------------CRCGPGGGS---- 442

Query: 824  QKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCN 883
                    + C    C  G VC  GL+  G+ GC                          
Sbjct: 443  --------LVCTPASCGLGEVC--GLLPSGQHGC-------------------------- 466

Query: 884  TCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDS 943
                             A C  +GD HY+T DG  + F G CEY L+   C G     ++
Sbjct: 467  ------------QPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY-LLSAPCHGPPLGAEN 513

Query: 944  FRVVTENVPCGTTGTTCSKAIKIFLGGFELKLS---HGKVEVIGTDESQEVPYTIRQM-- 998
            F V   N   G+   + ++++ + +    L LS     K++V G   +  +P+ +  +  
Sbjct: 514  FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVA--LPFQLDSLLH 571

Query: 999  ----GIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSV 1054
                G  +VV T  GL L +D  + + + +   +   +CGLCGN++    +D        
Sbjct: 572  AHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKP 631

Query: 1055 VGDVLEFGNSWKL--SPSCPDALAP--KDPCTANPFRKSWAQKQCSIL---HGPTFAACH 1107
             G        W++  +  C + ++     PCT            C ++    GP  A CH
Sbjct: 632  AG--------WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGP-LAPCH 682

Query: 1108 AHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCD 1166
              V PA+Y++ C+ DAC     G     C AVA Y  AC   G  +  WR P  CPL C 
Sbjct: 683  GLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCP 740

Query: 1167 YYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVA 1226
             ++       HY+ CG  C  +C +        +   EGC   C  E  + D   +    
Sbjct: 741  AHS-------HYELCGDSCPVSCPS--------LSAPEGCESAC-REGCVCDAGFVLSGD 784

Query: 1227 TCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQ-SCLCTERGVECTYKAEACVCTYNGQRFH 1285
            TC  P     C   G+ Y  G V      C+  C C   G     +  AC   +   R  
Sbjct: 785  TC-VPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAAC-GPHEECRLE 842

Query: 1286 PGDVIYHTTDGTGGCISARCGANG-----TIERRVY 1316
             G    H T    GC   RC ANG     T++ RVY
Sbjct: 843  DGVQACHAT----GC--GRCLANGGIHYITLDGRVY 872



 Score =  186 bits (471), Expect = 3e-46
 Identities = 153/557 (27%), Positives = 249/557 (44%), Gaps = 61/557 (10%)

Query: 69   VRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQ 126
            V+A +    GR C   G  HY T DG V+   G C+YV ++ C      EDF+I L   +
Sbjct: 845  VQACHATGCGR-CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVL---E 900

Query: 127  ESAAPTLSRVLMKVDGVVIQLTKGS-VLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGL 185
            ++AA  L R+L+ V G V+ L +G  V V+G  V LP +   V +        ++   GL
Sbjct: 901  KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGL 960

Query: 186  VLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME-FGNLQKMDDP 244
             L+++ D  LL+ + + +  + CGLCG+FNG      +L + +  + +E FG   ++   
Sbjct: 961  RLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGS 1020

Query: 245  TEQCQDPVPEPPRNCSTGFG----------ICEELLHGQ-LFSGCVALVDVGSYLEACRQ 293
            ++ C +     P+ C                C +L + Q  F+ C A++    Y   C  
Sbjct: 1021 SKGCGEGC--GPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVY 1078

Query: 294  DLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD 353
            DLC  +     + +C +LA Y+  C  AG   + WR   FCP  CP +  Y  C   C  
Sbjct: 1079 DLCAQKGDK--AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQG 1136

Query: 354  TCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP--GATYST 411
            +C+       C   C  GC C +  +L    Q  C+PV  C C +NG  Y P   +  ++
Sbjct: 1137 SCAALSGLTGCTTRCFEGCECDDRFLL---SQGVCIPVQDCGCTHNG-RYLPVNSSLLTS 1192

Query: 412  DCT-NCTCSGGR-WSCQEVPCP------------------GTCSVLGGAHFSTFDGKQYT 451
            DC+  C+CS     +CQ   CP                  G C +  GA+ +TFDG +  
Sbjct: 1193 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 1252

Query: 452  VHGDCSYVLTKPCDSSA-----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKAS 506
                  Y L+  C         + V+AE++ C    +E   +      DG+ T+   K  
Sbjct: 1253 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICH-GKTEAVGQVHIFFQDGMVTLTPNKG- 1310

Query: 507  GEVFLNQIYTQLPI-SAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRG 565
              V++N +   LP    A+V++ R     ++ +   G+Q  + L    ++ + ++    G
Sbjct: 1311 --VWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQ--VWLGANGKVAVIVSNDHAG 1366

Query: 566  QTCGLCGNFNSIQADDF 582
            + CG CGNF+  Q +D+
Sbjct: 1367 KLCGACGNFDGDQTNDW 1383



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 60/263 (22%), Positives = 95/263 (36%), Gaps = 51/263 (19%)

Query: 823  CQKSCHTLD-MTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVG 881
            CQ SC  L  +T  + +C  GC C D  +   +G CI  +DC C HN        ++   
Sbjct: 1134 CQGSCAALSGLTGCTTRCFEGCECDDRFLLS-QGVCIPVQDCGCTHNGRYLPVNSSLLTS 1192

Query: 882  --CNTCTCDSRMW----------------RCTDDPCLAT---CAVYGDGHYLTFDGQSYS 920
                 C+C S                   +     C AT   C +    +  TFDG   +
Sbjct: 1193 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 1252

Query: 921  FNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPC----------------GTTGTTCSKAI 964
                  Y L  + C G  +T   +RVV E   C                G    T +K +
Sbjct: 1253 TTSPGVYEL-SSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGV 1311

Query: 965  KIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINL 1024
              ++ G  + L   K+  +    + +    +RQ           G+ +       + + +
Sbjct: 1312 --WVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKA---------GVQVWLGANGKVAVIV 1360

Query: 1025 SPEFKGRVCGLCGNFDDIAVNDF 1047
            S +  G++CG CGNFD    ND+
Sbjct: 1361 SNDHAGKLCGACGNFDGDQTNDW 1383


>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
          Length = 1950

 Score =  347 bits (889), Expect = 9e-95
 Identities = 204/596 (34%), Positives = 293/596 (49%), Gaps = 39/596 (6%)

Query: 256  PRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYS 315
            P      + +CE+   G    G VA +    Y   C  + C   D    +  C T +E S
Sbjct: 661  PNAVGKSYEVCED---GIQKCGKVAALS-NDYKMICIDEYCQTRDK---TSTCDTYSELS 713

Query: 316  RQCTHAG-GLPQDWRGPD--FCP-QKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAG 371
            R C   G G  + WR      C  Q+CP    Y EC      TCSN    +  E  CV+G
Sbjct: 714  RLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPFQDSE--CVSG 771

Query: 372  CFCPEGTVLDDIGQTG-CVPVSKCACVYNGAAYAPGATYSTDC-TNCTCSGGRWSCQEVP 429
            C CPEG +LDDIG+ G CV  ++C C  +G  Y PG      C + CTC   +WSC E  
Sbjct: 772  CTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEAL 831

Query: 430  CPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKS 489
            CPG C V G +  +TFDG +Y   G+C ++     D   +++  ELR C    + TCL S
Sbjct: 832  CPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVHNED---WSISVELRPCPSGQTGTCLNS 887

Query: 490  VTLSLDGVQTV--VVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNL 547
            VTL L+    V   V  + G V  ++I  Q    +  + IF  S+ ++  +T   ++L +
Sbjct: 888  VTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQI 947

Query: 548  QLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACP 607
            Q+VP MQL++ + P     T GLCG++N+   DDF +   ++E T+ AF N+++  + CP
Sbjct: 948  QIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-CP 1006

Query: 608  NIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERS 667
                S      +S+E EK+A+  C  L D+ GP   CH  V P  Y+  C   TC CE S
Sbjct: 1007 KGNPS----SCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENS 1062

Query: 668  EDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEG 727
            +DCLC  L +YV ACA K   + GWR G+C     +CP  + + Y+V  C  +CRSLSE 
Sbjct: 1063 QDCLCTILGNYVKACAEKETYIVGWRTGLCEH---SCPSGLVFKYNVKACNSSCRSLSER 1119

Query: 728  DITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTH 787
            D +C V  +PVDGC CP   + ++ G CV  S C CY    ++  G+ +H     C C  
Sbjct: 1120 DRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTDDNKCVCRD 1179

Query: 788  GKLSCIGGQAPAPV----CAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQC 839
            G L C   Q P  +    C+    + DC +           ++C T ++  +   C
Sbjct: 1180 GILLC---QIPIDLTLQNCSGGAEYVDCSDP---KAQRRTNRTCSTRNIPVFDDYC 1229



 Score =  252 bits (644), Expect = 2e-66
 Identities = 180/573 (31%), Positives = 245/573 (42%), Gaps = 56/573 (9%)

Query: 1028 FKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPKDPCTANPFR 1087
            F+G+VCGLCGN +    +DF TR  SV    LEFGNSWK S  C D +A   PC +NP+ 
Sbjct: 1260 FQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYC 1319

Query: 1088 KSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACH 1147
            K+WA ++C IL   TF  CH  V+P+ Y++ C+ +ACACD  G    FCTAVA YA+AC 
Sbjct: 1320 KAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS 1379

Query: 1148 EVGLCVSWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPR-GDCLRDVWGLEGC 1206
             VG+CVSWR P++CP++CDYYN  G+C WHY+PCG    +TC++   G     +  LEGC
Sbjct: 1380 AVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSL--LEGC 1437

Query: 1207 YPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGV 1266
            Y KCP  AP  DE+ M+CV+          C        P   V  D   ++C C    +
Sbjct: 1438 YAKCPDSAPYLDENTMKCVSL-------SECSCFYNDVIPAGGVIEDNCGRTCYCIAGQL 1490

Query: 1267 ECTYKAE-----ACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPT 1321
            EC+  A      A   T        G  I   T G     S       + E       P 
Sbjct: 1491 ECSETAPTNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPL 1550

Query: 1322 TPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAG------------TSPR 1369
            T    T  + ++ P++ +S +    G  S      S    TT G            TS R
Sbjct: 1551 TEPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSER 1610

Query: 1370 TRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVEC 1429
               P  S + P V G           S PG             + A    +  SP +   
Sbjct: 1611 AGTPRVSGATPAVGGG----------STPGEAGPGATVSGSTGVSAGS--ITASPGASAT 1658

Query: 1430 RAEDA-PGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSSSPA 1488
             +E +  G    ++G +       G T      + G+     +  Q     A S S   A
Sbjct: 1659 SSESSKSGTTGPSVGGK------TGATSSEATSSEGMS---GVTGQSLGSTAGSDSEITA 1709

Query: 1489 QTTPPTTSKTTE-TRASGSSAPSSTPGTVSLSTARTTPAPGTATS------VKKTFSTPS 1541
            +T+   +S   + TR S  S    + GT       TT A G  TS           +T S
Sbjct: 1710 KTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTS 1769

Query: 1542 PPPVPATSTSSMSTTTPGTSVVSSKPTLTEPST 1574
                    TS    T PG + VS  P ++  +T
Sbjct: 1770 AGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGAT 1802



 Score =  152 bits (384), Expect = 3e-36
 Identities = 120/453 (26%), Positives = 196/453 (43%), Gaps = 57/453 (12%)

Query: 838  QCVPGCVCPDGLVADG---EGGCITAEDCPCVHNEASYRAGQTIRVGCNT-CTCDSRMWR 893
            +CV GC CP+G + D    +G C+   +CPC  +   Y+ G+     C + CTC    W 
Sbjct: 767  ECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWS 826

Query: 894  CTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPC 953
            CT+  C   C V G     TFDG  Y+F G+C +  V N          S  V     P 
Sbjct: 827  CTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVHNE-------DWSISVELRPCPS 878

Query: 954  GTTGTTCSKAIKIFLGGF----------ELKLSHGKVEVIGTDESQEVPYTIRQMGIYLV 1003
            G TGT C  ++ + L             +  +++ K+   G   S ++         YL 
Sbjct: 879  GQTGT-CLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQI-FNASSSYLQ 936

Query: 1004 VDT--DIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEF 1061
            V+T   + L +       +++++ P       GLCG++++ A +DF +    +      F
Sbjct: 937  VETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAF 996

Query: 1062 GNSWKLSPSCPDALAPKDPCTANPFRKS-WAQKQCSIL---HGPTFAACHAHVEPARYYE 1117
             NSW++  SCP      +P +     K  +A++ C IL    GP  A+CH  V P  Y+E
Sbjct: 997  ANSWEMM-SCPKG----NPSSCISIEKEKFAERHCGILLDSSGP-LASCHPIVNPKPYHE 1050

Query: 1118 ACVNDACACDSGGDCECFCTAVAAYAQACHE-VGLCVSWRTPSICPLFCDYYNPEGQC-E 1175
             C    C C++  D  C CT +  Y +AC E     V WRT       C++  P G   +
Sbjct: 1051 ECKKYTCTCENSQD--CLCTILGNYVKACAEKETYIVGWRTG-----LCEHSCPSGLVFK 1103

Query: 1176 WHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPP 1235
            ++ + C   C       R   + DV  ++GC   CP    ++  ++  CV          
Sbjct: 1104 YNVKACNSSCRSLSERDRSCDVEDV-PVDGC--TCPD--AMYQNNEGNCVLKSQCD---- 1154

Query: 1236 RCHVHGKSYRPGAVVPSDKNCQSCLCTERGVEC 1268
             C+++ +  +PG ++ +D N   C+C +  + C
Sbjct: 1155 -CYINDEVMQPGKLIHTDDN--KCVCRDGILLC 1184



 Score =  123 bits (309), Expect = 2e-27
 Identities = 175/770 (22%), Positives = 277/770 (35%), Gaps = 171/770 (22%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNI--QLRRSQESAAPT------ 132
            C   GS    TFDG  + FPG C+++   +     ED++I  +LR        T      
Sbjct: 836  CKVEGS-SLTTFDGVKYNFPGNCHFLAVHN-----EDWSISVELRPCPSGQTGTCLNSVT 889

Query: 133  --------LSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLG 184
                    + + +   DG V   T   +   G+     +S    +   SSSY +VE    
Sbjct: 890  LLLNSSVPVDKYVFNSDGTV---TNDKIRNQGYY----YSDKIQIFNASSSYLQVETYFH 942

Query: 185  LVLMWNHDD--SLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMD 242
            + L         L + +       T GLCG +N       + S N          L+K  
Sbjct: 943  VKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNI---------LEKTS 993

Query: 243  DPTEQCQDPVPEPPRNCSTGFGI---------CEELLHGQ-LFSGCVALVDVGSYLEACR 292
                   + +  P  N S+   I         C  LL      + C  +V+   Y E C+
Sbjct: 994  QAFANSWEMMSCPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECK 1053

Query: 293  QDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCA 352
            +  C CE++    C+C  L  Y + C         WR    C   CP+ + +        
Sbjct: 1054 KYTCTCENSQ--DCLCTILGNYVKACAEKETYIVGWR-TGLCEHSCPSGLVF-------- 1102

Query: 353  DTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTD 412
                 + + +AC   C +         ++D      VPV  C C        P A Y  +
Sbjct: 1103 -----KYNVKACNSSCRSLSERDRSCDVED------VPVDGCTC--------PDAMYQNN 1143

Query: 413  CTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVL 472
                                                     G+C  VL   CD      +
Sbjct: 1144 ----------------------------------------EGNC--VLKSQCDCYINDEV 1161

Query: 473  AELRRCGLTDSETCLKSVTLSLDGVQTVVVIK--ASGEVFLN------QIYTQLPISAAN 524
             +  +   TD   C+    + L  +   + ++  + G  +++      Q  T    S  N
Sbjct: 1162 MQPGKLIHTDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRN 1221

Query: 525  VTIF------RPSTFFIIAQT----SLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNF 574
            + +F         TF I+ ++      GL  + +++   Q          G+ CGLCGN 
Sbjct: 1222 IPVFDDYCGHENGTFRILTESVPCCEDGLTCSRKIIVAFQ----------GKVCGLCGNN 1271

Query: 575  NSIQADDFRTLSGVVEATAAAFFNTFKTQAACPN-IRNSFEDPCSLSVENEKYAQHWCSQ 633
            N    DDF T    V + A  F N++KT   C + +  +F  PC  +   + +A   C  
Sbjct: 1272 NGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTF--PCDSNPYCKAWAVRKCEI 1329

Query: 634  LTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCL--CAALSSYVHACAAKGVQLGG 691
            L D+   F  CH  V P  Y+  C+ + C C+     L  C A++ Y  AC+A GV +  
Sbjct: 1330 LRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSW 1387

Query: 692  WRDGVCTK--PMTTCPKSMTYHYHV--STCQPTCRSLSEGDITCSVGFIPVDGCI--CP- 744
             +  +C         P    +HY    +    TC+    G    S+    ++GC   CP 
Sbjct: 1388 RKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSL----LEGCYAKCPD 1443

Query: 745  KGTFLDD-TGKCVQASNCPCYHRGSMIPNGESVHDS-GAICTCTHGKLSC 792
               +LD+ T KCV  S C C++   +IP G  + D+ G  C C  G+L C
Sbjct: 1444 SAPYLDENTMKCVSLSECSCFY-NDVIPAGGVIEDNCGRTCYCIAGQLEC 1492



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 68/243 (27%), Positives = 102/243 (41%), Gaps = 26/243 (10%)

Query: 203  YANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNLQKMDDPTEQCQDPVPEPPRNCS 260
            +  K CGLCG+ NG  +  +  +  + +    +EFGN  K    +++C D V +     S
Sbjct: 1260 FQGKVCGLCGNNNG-DLKDDFTTRYSSVASGALEFGNSWKT---SQECSDTVAQTFPCDS 1315

Query: 261  TGFGICE-------ELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAE 313
              +  C+       E+L    F  C   VD  +Y + C ++ C C+        C  +A 
Sbjct: 1316 NPY--CKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAM 1373

Query: 314  YSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECR---SPC----ADTCSNQEHSRACED 366
            Y+  C+ A G+   WR P+ CP  C       ECR    PC    A TC +Q   +    
Sbjct: 1374 YAEACS-AVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSS 1432

Query: 367  HCVAGCF--CPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGRWS 424
              + GC+  CP+     D     CV +S+C+C YN    A G         C C  G+  
Sbjct: 1433 -LLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGGVIEDNCGRTCYCIAGQLE 1491

Query: 425  CQE 427
            C E
Sbjct: 1492 CSE 1494



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 47/159 (29%), Positives = 68/159 (42%), Gaps = 16/159 (10%)

Query: 823  CQKSCHTL---DMTCYSPQC-VPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTI 878
            C  SC +L   D +C      V GC CPD +  + EG C+    C C  N+   + G+ I
Sbjct: 1109 CNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLI 1168

Query: 879  RVGCNTCTCDSRMWRC--TDDPCLATCAVYGDGHYLTFDGQSYS--FNGDC---EYTLVQ 931
                N C C   +  C    D  L  C+  G   Y+           N  C      +  
Sbjct: 1169 HTDDNKCVCRDGILLCQIPIDLTLQNCS--GGAEYVDCSDPKAQRRTNRTCSTRNIPVFD 1226

Query: 932  NHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGG 970
            ++CG ++ T   FR++TE+VPC   G TCS+ I +   G
Sbjct: 1227 DYCGHENGT---FRILTESVPCCEDGLTCSRKIIVAFQG 1262



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 48/160 (30%), Positives = 71/160 (44%), Gaps = 10/160 (6%)

Query: 1850 TSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTA 1909
            T  P+T P T      S    ++S     T  +  T T ++    TT     +TT A + 
Sbjct: 1546 TLGPLTEPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASE 1605

Query: 1910 RTTS-APTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTT----SITSAPTTSTTSAPT 1964
             T+  A T R + A+PA    G G+TP      +T+S  T     SIT++P  S TS+ +
Sbjct: 1606 NTSERAGTPRVSGATPAV---GGGSTPGEAGPGATVSGSTGVSAGSITASPGASATSSES 1662

Query: 1965 SS--TTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSG 2002
            S   TT       T A +S  TSS   S  +  +  +T+G
Sbjct: 1663 SKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAG 1702



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 54/178 (30%), Positives = 72/178 (40%), Gaps = 31/178 (17%)

Query: 1855 TAPSTPSGRAISPTQSTSSWQKSRTTTLVT---TSTTSTPQTSTTYAHTTSTTSAPTART 1911
            TAP T S  A+S T +T+        TLVT   ++  S P  +T+ + TT TT  P    
Sbjct: 1495 TAP-TNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLTEP 1553

Query: 1912 TSAPTTRTTSASPASTTSGPGNT--PSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTS 1969
             +   T  TS    ST+   G T   SP  T ++  A TT    A TT   S  TS    
Sbjct: 1554 FTTGITE-TSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERAG 1612

Query: 1970 APTTS-----------------------TTSAPTSSTTSSPQTSTTSAPTT-STTSGP 2003
             P  S                       +T     S T+SP  S TS+ ++ S T+GP
Sbjct: 1613 TPRVSGATPAVGGGSTPGEAGPGATVSGSTGVSAGSITASPGASATSSESSKSGTTGP 1670



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 43/165 (26%), Positives = 66/165 (40%), Gaps = 6/165 (3%)

Query: 1851 STPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTAR 1910
            ST V+A S  +    S T S SS  KS TT       T    +  T +   S  +  +  
Sbjct: 1641 STGVSAGSITASPGASATSSESS--KSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLG 1698

Query: 1911 TTSAPTTRTTSASPASTTSGPGNTPSPVP-TTSTISAPTTSITSAPTTSTTSAPTS---S 1966
            +T+   +  T+ +  + +S PG    P P +    S  TT   +  TT      TS    
Sbjct: 1699 STAGSDSEITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALG 1758

Query: 1967 TTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVP 2011
            +T     +TTSA + +T  +  T  T    T+ +  P  +P   P
Sbjct: 1759 STEGSVEATTSAGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGATP 1803



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 19/46 (41%), Positives = 28/46 (60%)

Query: 82  STWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQE 127
           STW    YK+F+G +F F   C Y F  HC  +  DFNI+++R+ +
Sbjct: 598 STWSKGAYKSFNGRIFFFESSCPYTFCRHCIESGGDFNIEIKRNND 643



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 36/122 (29%), Positives = 54/122 (44%), Gaps = 15/122 (12%)

Query: 1898 AHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTT 1957
            + T  T S     TT+A T  +T A+    T GP +T + +P  +T S+ TT  T  P T
Sbjct: 1493 SETAPTNSTFAVSTTTATTILSTGAAITLVTGGP-STAASIPAITTSSSETTGTTLGPLT 1551

Query: 1958 -------STTSAPTSSTTSAPTTSTTSAPT-------SSTTSSPQTSTTSAPTTSTTSGP 2003
                   + TS P  ST+     +   +PT       + TT     +TT A + +T+   
Sbjct: 1552 EPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA 1611

Query: 2004 GT 2005
            GT
Sbjct: 1612 GT 1613



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 10/165 (6%)

Query: 1849 VTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTS----TPQTSTTYAHTTSTT 1904
            +T++P  A +T S  + S T   S   K+  T+   TS+      T Q+  + A + S  
Sbjct: 1649 ITASP-GASATSSESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEI 1707

Query: 1905 SAPTARTTSAPTTRTTSASPASTTSGPGNTP--SPVPTTSTISAPTTSI---TSAPTTST 1959
            +A T+ T S+P  + T  SP S     G T     V TT      T+     T     +T
Sbjct: 1708 TAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEAT 1767

Query: 1960 TSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPG 2004
            TSA + +T     T  T    ++ + +P  S  + P    +S PG
Sbjct: 1768 TSAGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGATPGAPGSSTPG 1812



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 51/178 (28%), Positives = 70/178 (39%), Gaps = 20/178 (11%)

Query: 1849 VTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPT 1908
            +T+      S+P G+   P+  +       TT     +TT     +T+ A    +T    
Sbjct: 1707 ITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGA--LGSTEGSV 1764

Query: 1909 ARTTSAPTTRTTSASPASTTSGPGNTP-SPVPTTS---TISAPTTSITSAPTTSTTSAPT 1964
              TTSA +  T   S    T GPGNT  S  P  S   T  AP +S         TS   
Sbjct: 1765 EATTSAGSGNTAGTSGTGDT-GPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGK 1823

Query: 1965 SSTTSAPTTS---------TTSAPTSSTTSSPQTSTTSA--PTTSTTSG--PGTTPSP 2009
            S  +   + +         T +   +STTSSP +  T A   T  T SG  PGT  +P
Sbjct: 1824 SGKSGHDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTP 1881



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 27/63 (42%), Positives = 35/63 (55%), Gaps = 4/63 (6%)

Query: 1945 SAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPG 2004
            +APT S  +    STT+A T  +T A  T  T  P S+  S P  +T+S+ TT TT GP 
Sbjct: 1495 TAPTNSTFA---VSTTTATTILSTGAAITLVTGGP-STAASIPAITTSSSETTGTTLGPL 1550

Query: 2005 TTP 2007
            T P
Sbjct: 1551 TEP 1553



 Score = 40.8 bits (94), Expect = 0.014
 Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 13/86 (15%)

Query: 1939 PTTSTISAPTTSITS-----APTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQT---- 1989
            PT ST +  TT+ T+     A  T  T  P S+  S P  +T+S+ T+ TT  P T    
Sbjct: 1497 PTNSTFAVSTTTATTILSTGAAITLVTGGP-STAASIPAITTSSSETTGTTLGPLTEPFT 1555

Query: 1990 ---STTSAPTTSTTSGPGTTPSPVPT 2012
               + TS P  ST+   G T    PT
Sbjct: 1556 TGITETSVPIISTSGNAGMTGVVSPT 1581



 Score = 39.7 bits (91), Expect = 0.030
 Identities = 51/193 (26%), Positives = 70/193 (36%), Gaps = 41/193 (21%)

Query: 1855 TAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTT-- 1912
            T PS       + +++TSS   S  T     ST  +    T  A T+ T S+P  + T  
Sbjct: 1668 TGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEIT--AKTSFTGSSPPGKLTRP 1725

Query: 1913 --------SAPTTR-----TTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTST 1959
                    S  TT      TT A+  +T+   G+T   V  T++  +  T+ TS   T  
Sbjct: 1726 SPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSG--TGD 1783

Query: 1960 TSAPTSSTTSAPTTS---TTSAPTSSTTSSPQTSTTS-------------------APTT 1997
            T    ++ +  P  S   T  AP SST        TS                      T
Sbjct: 1784 TGPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRT 1843

Query: 1998 STTSGPGTTPSPV 2010
             T S   TT SPV
Sbjct: 1844 PTVSAASTTSSPV 1856



 Score = 35.0 bits (79), Expect = 0.74
 Identities = 23/59 (38%), Positives = 33/59 (55%), Gaps = 4/59 (6%)

Query: 1953 SAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTT-SAPTTSTTSGPGTTPSPV 2010
            +APT ST +    STT+A T  +T A  +  T  P T+ +  A TTS++   GTT  P+
Sbjct: 1495 TAPTNSTFAV---STTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPL 1550



 Score = 33.5 bits (75), Expect = 2.2
 Identities = 39/126 (30%), Positives = 53/126 (42%), Gaps = 15/126 (11%)

Query: 1434 APGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSSSPAQTTPP 1493
            +PG    A G       D+G T   +   SG   +  + V     L  + + S A TT  
Sbjct: 1798 SPGATPGAPGSSTPGEADIGNTSFGKSGKSG---HDSLTVLNPAFLRRTPTVSAASTTSS 1854

Query: 1494 TTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTPSPPPVPATSTSSM 1553
              SK T+       A S+T  T+S S   T   PG ATS  K  S  S     ++ TS+ 
Sbjct: 1855 PVSKHTD-------AASATAVTISGSKPGTPGTPGGATSGGKITSGWS-----SSGTSTG 1902

Query: 1554 STTTPG 1559
            S+ TPG
Sbjct: 1903 SSNTPG 1908


>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein
            [Homo sapiens]
          Length = 1472

 Score =  315 bits (807), Expect = 3e-85
 Identities = 262/968 (27%), Positives = 391/968 (40%), Gaps = 154/968 (15%)

Query: 70   RASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQE 127
            +A   A +  VC   G  HY TFDG  +   G C+Y   E C        F+++ +    
Sbjct: 522  KAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHR 581

Query: 128  SAAPT--LSRVLMKVDGVVIQLTKGSV---LVNGHPVLLP--FSQSGVLIQQSSSYTKVE 180
             +     +  V ++     + LT+G V   LV+     LP   S+  + + QS     VE
Sbjct: 582  GSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVE 641

Query: 181  ARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL 238
               GLV+ ++ D  L L L  ++ ++ CGLCG++NG P   + L+ +  L P  +EF + 
Sbjct: 642  LVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA-DDFLTPDGALAPDAVEFASS 700

Query: 239  QKMDDPTEQCQDPVPEPPRNCSTGFGICEE--LLHGQL------FSGCVALVDVGSYLEA 290
             K+DD    C+D        C+ G     E   L G L      F+ C   +D   +LE 
Sbjct: 701  WKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQ 760

Query: 291  CRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP 350
            C  DLC      L   +C  L+ Y++ C   G    DWR P  CP  CP N +Y  C   
Sbjct: 761  CVYDLCVVGGERL--SLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPA 818

Query: 351  CADTCSNQEHSRACEDH-CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
            C  +C+       C    CV GC C  G V        CVP S C C + G   APG   
Sbjct: 819  CPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG---GACVPASSCGCTFQGLQLAPGQEV 875

Query: 410  STD--CTN-CTCSGG--RWSCQEVP-CP-------------------GTCSVLGGAHFST 444
              D  C   CTC+G   + +C++   CP                   GTC   G  H+ +
Sbjct: 876  WADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVS 935

Query: 445  FDGKQYTVHGDCSYVLTKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTV 500
            FDG+++   G C+Y+L   C  +A    F VL E    G + + +  ++V +   GV+  
Sbjct: 936  FDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRG-SQTVSYTRAVRVEARGVKVA 994

Query: 501  VVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQ 558
            V  +  G+V ++ +   LP  AA+  V +FR     ++ +T  GL +        ++  +
Sbjct: 995  VRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVV-RTDFGLTVTYDW--NARVTAK 1051

Query: 559  LAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFK--TQAACPNIRNSFEDP 616
            +        CGLCGNFN   ADD     G   A A AF N+++  T+  C          
Sbjct: 1052 VPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPK 1111

Query: 617  CSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALS 676
                V  +  +++ C  L D  GPF  CH+ + P     +C++D C        LC AL+
Sbjct: 1112 LDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALA 1171

Query: 677  SYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITC--SVG 734
            +Y  AC A G  +  WR          CP S   H H   C   C  LS GD+      G
Sbjct: 1172 TYAAACQAAGATVHPWRS------EELCPLSCPPHSHYEACSYGC-PLSCGDLPVPGGCG 1224

Query: 735  FIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIG 794
                +GC+C +G  L     C+  ++C C H+G+  P G++ +                 
Sbjct: 1225 SECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFY----------------- 1266

Query: 795  GQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGE 854
                                     G GC   CH  +                       
Sbjct: 1267 ------------------------PGPGCDSLCHCQE----------------------- 1279

Query: 855  GGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTF 914
            GG ++ E   C  +EA   +G ++  GC                  +TC   GD HY TF
Sbjct: 1280 GGLVSCESSSCGPHEACQPSGGSL--GCVAVGS-------------STCQASGDPHYTTF 1324

Query: 915  DGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELK 974
            DG+ + F G C Y L Q  CG +      F V+ ENV  G    + ++ I + +  F L+
Sbjct: 1325 DGRRFDFMGTCVYVLAQT-CGTRPGLH-RFAVLQENVAWGNGRVSVTRVITVQVANFTLR 1382

Query: 975  LSHGKVEV 982
            L   + +V
Sbjct: 1383 LEQRQWKV 1390



 Score =  169 bits (427), Expect = 3e-41
 Identities = 153/544 (28%), Positives = 219/544 (40%), Gaps = 96/544 (17%)

Query: 820  GAGCQKSCH--TLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQT 877
            G  C  SC+       C    CV GCVC  G VA G G C+ A  C C         GQ 
Sbjct: 816  GPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG-GACVPASSCGCTFQGLQLAPGQE 874

Query: 878  I--------RVGCN------------------TCTCDSRMWRCTDDPCLATCAVYGDGHY 911
            +        R  CN                   C+  + +  C  D    TC   GD HY
Sbjct: 875  VWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDR-FGTCQGSGDPHY 933

Query: 912  LTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGF 971
            ++FDG+ + F G C Y LV + CG +++   +FRV+ EN   G+   + ++A+++   G 
Sbjct: 934  VSFDGRRFDFMGTCTYLLVGS-CG-QNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGV 991

Query: 972  ELKLSHGKV-EVIGTDESQEVPYT-------IRQMGIYLVVDTDIGLVLLWDKKTSIFIN 1023
            ++ +      +V+  D  Q +P+        + + G   VV TD GL + +D    +   
Sbjct: 992  KVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAK 1051

Query: 1024 LSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSW--KLSPSC----PDALAP 1077
            +   +   +CGLCGNF+    +D A R      + L FGNSW  +  P C    P     
Sbjct: 1052 VPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPK 1111

Query: 1078 KDPCTANPFRKSWAQKQCSILHGP--TFAACHAHVEPARYYEACVNDACACDSGGDCECF 1135
             D   A   +   ++ +C IL  P   F  CH+ ++P      CV D C     G     
Sbjct: 1112 LDSLVAQQLQ---SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP--GQSGPL 1166

Query: 1136 CTAVAAYAQACHEVGLCV-SWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRG 1194
            C A+A YA AC   G  V  WR+  +CPL C  ++       HY+ C   C  +C    G
Sbjct: 1167 CDALATYAAACQAAGATVHPWRSEELCPLSCPPHS-------HYEACSYGCPLSC----G 1215

Query: 1195 DCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDK 1254
            D    V G  GC  +C  E  + DE       +C  P     C   G  + PG       
Sbjct: 1216 DL--PVPG--GCGSEC-HEGCVCDEGFALSGESC-LPLASCGCVHQGTYHPPGQTFYPGP 1269

Query: 1255 NCQS-CLCTERG-VECTYKA----EACVCTYNGQRFHPGDVIYHTTDGTGGCI---SARC 1305
             C S C C E G V C   +    EAC                  + G+ GC+   S+ C
Sbjct: 1270 GCDSLCHCQEGGLVSCESSSCGPHEAC----------------QPSGGSLGCVAVGSSTC 1313

Query: 1306 GANG 1309
             A+G
Sbjct: 1314 QASG 1317



 Score =  155 bits (391), Expect = 5e-37
 Identities = 118/381 (30%), Positives = 167/381 (43%), Gaps = 44/381 (11%)

Query: 901  ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTC 960
            A C   GD HY TFDG+ Y   G C YT+V+     +D T  +F V  +N   G+   + 
Sbjct: 531  AVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE--LCSEDDTLPAFSVEAKNEHRGSRRVSY 588

Query: 961  SKAIKIFLGGFELKLSHGKVEVIGTDESQ--------EVPYTIRQMGIYLVVDTDIGLVL 1012
               + +      + L+ G+V  +  D  +        E    + Q G   VV+   GLV+
Sbjct: 589  VGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVV 648

Query: 1013 LWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPS-- 1070
             +D    + ++L   F+ +VCGLCGN++    +DF T   ++  D +EF +SWKL     
Sbjct: 649  TYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDY 708

Query: 1071 -CPDALAPKDP-CTANPFRKSWAQKQCSI---LHGPTFAACHAHVEPARYYEACVNDACA 1125
             C D      P CT    +     + C +   L GP FA CH  ++P  + E CV D C 
Sbjct: 709  LCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP-FAVCHDTLDPRPFLEQCVYDLCV 767

Query: 1126 CDSGGDCECFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCDYYNPEGQCEWHYQPCGVP 1184
               GG+    C  ++AYAQAC E+G+ V  WR+P+ CPL C            Y+ CG  
Sbjct: 768  V--GGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC-------PANSRYELCGPA 818

Query: 1185 CLRTCRN---PRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHG 1241
            C  +C     P     R    +EGC   C    P F      CV     P     C   G
Sbjct: 819  CPTSCNGAAAPSNCSGRPC--VEGCV--C---LPGFVASGGACV-----PASSCGCTFQG 866

Query: 1242 KSYRPGAVVPSDKNCQ-SCLC 1261
                PG  V +D+ CQ  C C
Sbjct: 867  LQLAPGQEVWADELCQRRCTC 887



 Score =  155 bits (391), Expect = 5e-37
 Identities = 132/479 (27%), Positives = 193/479 (40%), Gaps = 57/479 (11%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCG--AAYEDFNIQLRRSQESAAPTLS---R 135
            C   G  HY +FDG  F F G C Y+    CG  AA   F + L  ++   + T+S    
Sbjct: 925  CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRV-LVENEHRGSQTVSYTRA 983

Query: 136  VLMKVDGVVIQLTK---GSVLVNGHPVLLPFSQSGVLIQ--QSSSYTKVEARLGLVLMWN 190
            V ++  GV + + +   G VLV+     LPF  +   +Q  +      V    GL + ++
Sbjct: 984  VRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYD 1043

Query: 191  HDDSLLLELDTKYANKTCGLCGDFNGMPVVS-ELLSHNTKLTPMEFGNL-QKMDDPTEQC 248
             +  +  ++ + YA   CGLCG+FNG P     L         + FGN  Q+   P    
Sbjct: 1044 WNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGA 1103

Query: 249  QDPVPEPPRNCSTGFGICEELLHGQL------FSGCVALVDVGSYLEACRQDLCFCEDTD 302
             +P   P  +      +  +   G L      F  C + +D    +  C  D C      
Sbjct: 1104 TEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQS 1163

Query: 303  LLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSR 362
                +C  LA Y+  C  AG     WR  + CP  CP +  Y  C   C  +C +     
Sbjct: 1164 --GPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPG 1221

Query: 363  ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTC- 418
             C   C  GC C EG  L       C+P++ C CV+ G  + PG T+     C + C C 
Sbjct: 1222 GCGSECHEGCVCDEGFALSG---ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQ 1278

Query: 419  SGGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVHGDCSYV 459
             GG  SC+   C                     TC   G  H++TFDG+++   G C YV
Sbjct: 1279 EGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYV 1338

Query: 460  LTKPCDS----SAFTVLAE-----LRRCGLTDSETC-LKSVTLSLDGVQTVVVIKASGE 508
            L + C +      F VL E       R  +T   T  + + TL L+  Q  V ++A GE
Sbjct: 1339 LAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVRADGE 1397



 Score =  151 bits (381), Expect = 7e-36
 Identities = 128/453 (28%), Positives = 186/453 (41%), Gaps = 82/453 (18%)

Query: 400 GAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPG--TCSVLGGA----------------- 440
           G A A G   + DC     S    SC+ + C     C V+GG                  
Sbjct: 480 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDP 539

Query: 441 HFSTFDGKQYTVHGDCSYVLTKPCDSS----AFTVLAELRRCGLTDSETCLKSVTLSLDG 496
           H++TFDG++Y + G CSY + + C       AF+V A+    G         S  +S  G
Sbjct: 540 HYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRG---------SRRVSYVG 590

Query: 497 VQTVVVIKAS--------GEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLN 546
           + TV     S        G V ++   ++LP+S +   + +++     ++       +L 
Sbjct: 591 LVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVV-------ELV 643

Query: 547 LQLVPTM----QLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT 602
             LV T     QL + L  + + Q CGLCGN+N   ADDF T  G +   A  F +++K 
Sbjct: 644 FGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKL 703

Query: 603 QAACPNIRNSFEDPCSLSVENEKYAQHW-----CSQLTDADGPFGRCHAAVKPGTYYSNC 657
                   +  ++ C      +  AQH+     C  LT  DGPF  CH  + P  +   C
Sbjct: 704 DDGDYLCEDGCQNNCPACTPGQ--AQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQC 761

Query: 658 MFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTC 717
           ++D C        LC  LS+Y  AC   G+ +G WR          CP S   +     C
Sbjct: 762 VYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS------PANCPLSCPANSRYELC 815

Query: 718 QPTCRSLSEG---DITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGE 774
            P C +   G      CS G   V+GC+C  G F+   G CV AS+C C  +G  +  G+
Sbjct: 816 GPACPTSCNGAAAPSNCS-GRPCVEGCVCLPG-FVASGGACVPASSCGCTFQGLQLAPGQ 873

Query: 775 SVHDSGAI---CTC---TH-----GKLSCIGGQ 796
            V         CTC   TH      K SC  G+
Sbjct: 874 EVWADELCQRRCTCNGATHQVTCRDKQSCPAGE 906


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score =  290 bits (741), Expect = 1e-77
 Identities = 232/803 (28%), Positives = 343/803 (42%), Gaps = 79/803 (9%)

Query: 73   NPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESA--- 129
            +P      C  +G  HY TFDG  F F G C Y+ ++ CG + + F     +++E     
Sbjct: 1148 HPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEG 1207

Query: 130  APTLSRVLMKVDGVVIQLTKGS-VLVNGHPVLLPFSQS-GVLIQQSSSYTKVEARLGLVL 187
               LS+V + +    + L KG   LV G  V LP   S GV +  S  + +++   GL +
Sbjct: 1208 VSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRV 1267

Query: 188  MWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSEL-LSHNTKLTPMEFGNLQKMD-DPT 245
             W+ D  L + + + Y+ K CGLCG+++G      L L  +      E GN  + D D  
Sbjct: 1268 RWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDED 1327

Query: 246  EQCQ--DPVPEPPRNCS-----TGFGICEELL--HGQLFSGCVALVDVGSYLEACRQDLC 296
            ++CQ    V  P  + S     +G G C  L+  HG  F  C+  V   S+ ++C  D+C
Sbjct: 1328 QECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLDMC 1386

Query: 297  FCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCS 356
              +    L  +C  ++  +  C  AG   + WR P FCP  CP N +Y  C  PC DTC 
Sbjct: 1387 GFQGLQHL--LCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH 1444

Query: 357  NQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAY--APGATYSTDCT 414
            +      C D CV  C C  G VL  +    C+P S+C C++   +Y       Y   C 
Sbjct: 1445 SGFSGMFCSDRCVEACECNPGFVLSGL---ECIPRSQCGCLHPAGSYFKVGERWYKPGCK 1501

Query: 415  N-CTC-SGGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVH 453
              C C S  R  CQ   C                     TC+  G  H+ TFDG  +   
Sbjct: 1502 ELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFM 1561

Query: 454  GDCSYVLTKPC----DSSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEV 509
            G C+YVLT+PC      S F V A     G     + +K+V +++  +   + +    +V
Sbjct: 1562 GTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLS--ISLLRGCKV 1619

Query: 510  FLNQIYTQLPI--SAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQT 567
             LN     LP+  +   VTI R S+  ++  T+ GLQ+       ++  + +     GQ 
Sbjct: 1620 MLNGHRVALPVWLAQGRVTI-RLSSNLVLLYTNFGLQVRYDGSHLVE--VTVPSSYGGQL 1676

Query: 568  CGLCGNFNSIQADD----FRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVEN 623
            CGLCGN+N+   DD     R L+G      AA+     ++  C  +          S + 
Sbjct: 1677 CGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGK-----PSSCQE 1731

Query: 624  EKYAQHW---CSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVH 680
               A  W   C+ L +  GPF +CH  V P + +++C+   C  +     LC +L +Y  
Sbjct: 1732 NSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYAS 1791

Query: 681  ACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDG 740
             CA  G Q   WR+     PM  CP   +Y    S C  TC S++     C       + 
Sbjct: 1792 LCAQAG-QAPAWRNRTFC-PM-RCPPGSSYSPCSSPCPDTCSSIN-NPRDCPKALPCAES 1847

Query: 741  CICPKGTFLDDTGKCVQASNCPCYH-RGSMIPNGESVHDSGA---ICTCT-HGKLSCIGG 795
            C C KG  L  T  CV    C C    GS  P GE  +       +CTC+ H  ++C   
Sbjct: 1848 CECQKGHILSGT-SCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQS 1906

Query: 796  QA-PAPVCAAPMVFFDCRNATPG 817
               P  +C A      CR +  G
Sbjct: 1907 TCKPNQICWALDGLLRCRASGVG 1929



 Score =  243 bits (619), Expect = 2e-63
 Identities = 211/793 (26%), Positives = 331/793 (41%), Gaps = 88/793 (11%)

Query: 75   AHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLS 134
            A     C+  G  HY TFDG +  F G C YV +  C +  +D    +  + E+    L 
Sbjct: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595

Query: 135  RVLMKVDGVV-----IQLTKG-SVLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLV 186
               +K   V      I L +G  V++NGH V LP   +Q  V I+ SS+   +    GL 
Sbjct: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655

Query: 187  LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMDDP 244
            + ++    + + + + Y  + CGLCG++N   +  + L  + KL    M+ G   K+ + 
Sbjct: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSL-DDNLRPDRKLAGDSMQLGAAWKLPES 1714

Query: 245  TEQCQDPVPEPPRNCSTGFGI------CEELLHGQ-LFSGCVALVDVGSYLEACRQDLCF 297
            +E     V   P +C            C  L++ Q  FS C  +V   S   +C    C 
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG 1774

Query: 298  CE-DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCS 356
             + DT  L   C +L  Y+  C  AG  P  WR   FCP +CP    Y  C SPC DTCS
Sbjct: 1775 TKGDTTAL---CRSLQAYASLCAQAGQAPA-WRNRTFCPMRCPPGSSYSPCSSPCPDTCS 1830

Query: 357  NQEHSRACEDH--CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP-GATYSTD- 412
            +  + R C     C   C C +G +L     T CVP+ +C C     +Y P G  + T+ 
Sbjct: 1831 SINNPRDCPKALPCAESCECQKGHILSG---TSCVPLGQCGCTDPAGSYHPVGERWYTEN 1887

Query: 413  -CTN-CTCS-GGRWSCQEVPCP-------------------GTCSVLGGAHFSTFDGKQY 450
             CT  CTCS     +C +  C                    G C + G +H+ +FDG  +
Sbjct: 1888 TCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNH 1947

Query: 451  TVHGDCSYVLTKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKAS 506
            ++   C+ VL K C  +     F + A+  +         L  V + +   Q  V ++  
Sbjct: 1948 SIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQ--VTLQKG 2005

Query: 507  GEVFLNQIYTQLP-ISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRG 565
              V +N     LP IS       + S+ + I    +G+Q+       +++  ++     G
Sbjct: 2006 HRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEI--EIPTTYYG 2063

Query: 566  QTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENEK 625
            + CG+CGNFN  + D+    S  V  + + F N++K +   P+ ++   D   +  E ++
Sbjct: 2064 KVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQE 2123

Query: 626  YAQHWCSQLTDADGPFGRCHAAVKPGT------------YYSNCMFDTCNCERSEDCLCA 673
                 C +  D      +C AA++               +  +C    C        LC 
Sbjct: 2124 NPSGNC-RAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQ 2182

Query: 674  ALSSYVHACAAKGVQLGGWRD-GVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCS 732
            AL ++   C ++G++   WR+   C      CP   +Y   + +C P+C  L   D  C 
Sbjct: 2183 ALQAFGATCQSQGLKPPLWRNSSFCP---LECPAYSSYTNCLPSCSPSCWDL---DGRCE 2236

Query: 733  VGFIP---VDGCICPKGTFLDDTGKCVQASNCPCYH-RGSMIPNGESVHDSGAI--CTCT 786
               +P    +GCIC  G  L +  KCV  S C C    G  IP G+S   SG    C CT
Sbjct: 2237 GAKVPSACAEGCICQPGYVLSE-DKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCT 2295

Query: 787  HGKLSCIGGQAPA 799
             G + C   + P+
Sbjct: 2296 GGAIQCGDFRCPS 2308



 Score =  193 bits (490), Expect = 2e-48
 Identities = 219/891 (24%), Positives = 322/891 (36%), Gaps = 162/891 (18%)

Query: 80   VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHC--GAAYEDFNIQLRRSQESA---APTLS 134
            VC   G  HY +FDG     P  C  V  + C    A   F I  +  +E     A  L 
Sbjct: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989

Query: 135  RVLMKVDGVVIQLTKGS-VLVNGHPVLLP-FSQ-SGVLIQQSSSYTKVEARLGLVLMWNH 191
             V + +    + L KG  VL+N   V LP  SQ  GV ++ SS Y+ V  ++G+ + ++ 
Sbjct: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049

Query: 192  DDSLLLELDTKYANKTCGLCGDFNGMPVVSELL-SHNTKLTPMEFGNLQKMDDPTEQCQD 250
            +  L +E+ T Y  K CG+CG+FN       ++ S     +  EF N  K  D    CQ 
Sbjct: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS 2109

Query: 251  PVPE-----------PPRNCSTGF-----GICEELLHGQLFSGCVALVDVGSYLEACRQD 294
             + +           P  NC           CE  L   +++ C + +D+  +L  C   
Sbjct: 2110 LLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANT 2169

Query: 295  LCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADT 354
            LC  E   L   +C  L  +   C   G  P  WR   FCP +CP    Y  C   C+ +
Sbjct: 2170 LC--EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPS 2227

Query: 355  CSNQE---HSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCAC--VYNGAAYAPGATY 409
            C + +           C  GC C  G VL    +  CVP S+C C   + G+     +  
Sbjct: 2228 CWDLDGRCEGAKVPSACAEGCICQPGYVL---SEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284

Query: 410  STDCT-NCTCSGGRWSCQEVPCPG---------------------TCSVLGGAHFSTFDG 447
            S+ CT  C C+GG   C +  CP                       CSV G   + TFDG
Sbjct: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344

Query: 448  KQYTVHGDCSYVLTKPCD---SSAFTVLAELR-RCGLTDSETCLKSVTLSLDGVQTVVVI 503
              Y + G  +YVL K  D        +L E R +     S   L+ V  ++ G +  V +
Sbjct: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYK--VQL 2402

Query: 504  KASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQL--NLQLVPTM----QLFM 557
            +A  E+ +N     +P        +RP+    +      L L  + +LV +        +
Sbjct: 2403 QAGLELVVNNQKMAVP--------YRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI 2454

Query: 558  QLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT--------------- 602
             L     G   GLCGN++  + +D    SG +      F N+++                
Sbjct: 2455 SLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPA 2514

Query: 603  ----QAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCM 658
                Q A   +R   +       +    +   C  L D  GPF  CH  V P  +  +C+
Sbjct: 2515 EEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574

Query: 659  FDTCNCE---RSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVS 715
             D C+ +     E+  C  LS +                GV ++            YH+S
Sbjct: 2575 LDLCSAQDPREQEELRCQVLSGH----------------GVSSR------------YHIS 2606

Query: 716  TCQPTCRSLSEGDITCSVGFIPVDGCICP-KGTFLDDTGKCVQ------ASNCPCYHRGS 768
                T  S     I C  G     G   P +G        C+Q       ++C C   G 
Sbjct: 2607 ELYDTLPS-----ILCQPG--RPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGI 2659

Query: 769  MIPNGES--VHDSGAICTCTHGKL------SCIGGQAPAPVCAAPMVFFDCRNATPGDTG 820
                G S    D    CTC   ++      SC  G+    VC        C   +P    
Sbjct: 2660 YYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGE----VCTLGNHTQGCFPESP---- 2711

Query: 821  AGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEAS 871
              C ++    D  C        C C  G    G G C+   D P     AS
Sbjct: 2712 --CLQNPCQNDGQCREQGATFTCECEVGY---GGGLCMEPRDAPPPRKPAS 2757



 Score =  180 bits (457), Expect = 1e-44
 Identities = 140/492 (28%), Positives = 207/492 (42%), Gaps = 54/492 (10%)

Query: 336  QKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCA 395
            ++CP N +Y  C  P +  C +   S  C   C  GC C  G +  D     C+  S C 
Sbjct: 1042 ERCPPNARYESCACPAS--CKSPRPS--CGPLCREGCVCNPGFLFSD---NHCIQASSCN 1094

Query: 396  CVYNGAAYAPGAT-YSTDCT-NCTC-SGGRWSCQEVPC--------------------PG 432
            C YN   Y PGA  +S +CT +C C  G R  CQ   C                      
Sbjct: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154

Query: 433  TCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSA---FTVLAELRRCGLTDSETCLKS 489
            TC V G  H+ TFDG+ +   G C+Y+L +PC +S    F V A+    G  +  +CL  
Sbjct: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG-QEGVSCLSK 1213

Query: 490  VTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQL 549
            V ++L    TV ++K    +   Q  T LP   +       S  F+  QT  GL++    
Sbjct: 1214 VYVTLP-ESTVTLLKGRRTLVGGQQVT-LPAIPSKGVFLGASGRFVELQTEFGLRVRWD- 1270

Query: 550  VPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT----QAA 605
                QL++ ++    G+ CGLCGN++    +D   L G          N+++T       
Sbjct: 1271 -GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQE 1329

Query: 606  CPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCE 665
            C   +      C  S+++      +C +L D  GPF  C   VK  +++ +CM D C  +
Sbjct: 1330 CQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389

Query: 666  RSEDCLCAALSSYVHACAAKGVQLGGWRD-GVCTKPMTTCPKSMTYHYHVSTCQPTCRSL 724
              +  LC  +S+    C   G  +  WR+   C  PM  CP +  Y      C  TC S 
Sbjct: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFC--PM-ACPPNSKYSLCAKPCPDTCHSG 1446

Query: 725  SEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYH-RGSMIPNGESVHDSGA-- 781
              G + CS     V+ C C  G  L    +C+  S C C H  GS    GE  +  G   
Sbjct: 1447 FSG-MFCSDRC--VEACECNPGFVLSGL-ECIPRSQCGCLHPAGSYFKVGERWYKPGCKE 1502

Query: 782  ICTC-THGKLSC 792
            +C C ++ ++ C
Sbjct: 1503 LCVCESNNRIRC 1514



 Score =  172 bits (436), Expect = 3e-42
 Identities = 132/426 (30%), Positives = 191/426 (44%), Gaps = 58/426 (13%)

Query: 823  CQKSCHT--LDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASY-RAGQT-I 878
            C  +CH+    M C S +CV  C C  G V  G   CI    C C+H   SY + G+   
Sbjct: 1439 CPDTCHSGFSGMFC-SDRCVEACECNPGFVLSGLE-CIPRSQCGCLHPAGSYFKVGERWY 1496

Query: 879  RVGCNT-CTCDS------RMWRC-TDDPC-------------LATCAVYGDGHYLTFDGQ 917
            + GC   C C+S      + WRC   + C              ATC   GD HYLTFDG 
Sbjct: 1497 KPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGA 1556

Query: 918  SYSFNGDCEYTLVQNHCGGKDSTQDSFRVV--TENVPCGTTGTTCSKAIKIFLGGFELKL 975
             + F G C Y L +  C  +  +QDS+ VV  T     G    +  KA+ + +    + L
Sbjct: 1557 LHHFMGTCTYVLTRP-CWSR--SQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISL 1613

Query: 976  SHG-KVEVIGTDESQEV-----PYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFK 1029
              G KV + G   +  V       TIR     +++ T+ GL + +D    + + +   + 
Sbjct: 1614 LRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYG 1673

Query: 1030 GRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL----SPSCPDALAPKDPCTANP 1085
            G++CGLCGN+++ +++D     R + GD ++ G +WKL     P C         C  N 
Sbjct: 1674 GQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENS 1733

Query: 1086 FRKSWAQKQCSILHGP--TFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYA 1143
               +W  K C+IL  P   F+ CH  V P   + +CV+  C   + GD    C ++ AYA
Sbjct: 1734 MADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG--TKGDTTALCRSLQAYA 1790

Query: 1144 QACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTC---RNPRGDCLRDV 1200
              C + G   +WR  + CP+ C    P G     Y PC  PC  TC    NPR DC + +
Sbjct: 1791 SLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSPCPDTCSSINNPR-DCPKAL 1842

Query: 1201 WGLEGC 1206
               E C
Sbjct: 1843 PCAESC 1848



 Score =  170 bits (431), Expect = 1e-41
 Identities = 149/530 (28%), Positives = 211/530 (39%), Gaps = 85/530 (16%)

Query: 823  CQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQT----- 877
            C  SC +   +C  P C  GCVC  G +   +  CI A  C C +N   Y  G       
Sbjct: 1055 CPASCKSPRPSC-GPLCREGCVCNPGFLFS-DNHCIQASSCNCFYNNDYYEPGAEWFSPN 1112

Query: 878  ----------IRVGCNTCTCDSR--------MWRCTDDPCLATCAVYGDGHYLTFDGQSY 919
                       RV C    C +          + C      ATC VYGD HY+TFDG+ +
Sbjct: 1113 CTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHF 1172

Query: 920  SFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGK 979
             F G C Y L Q  CG  +ST   FRV  +N   G  G +C   + + L    + L  G+
Sbjct: 1173 GFMGKCTYILAQP-CG--NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR 1229

Query: 980  VEVIGTDESQEVPY-TIRQMGIYL-------VVDTDIGLVLLWDKKTSIFINLSPEFKGR 1031
              ++G    Q+V    I   G++L        + T+ GL + WD    +++ +S  + G+
Sbjct: 1230 RTLVG---GQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGK 1286

Query: 1032 VCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL----SPSCPDALAPKDPCTANPFR 1087
            +CGLCGN+D  + ND      S  GD  E GNSW+        C        P   +  +
Sbjct: 1287 LCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQ 1346

Query: 1088 KSWAQKQ-CSIL---HGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYA 1143
             S +    C  L   HGP F  C  HV+ A ++++C+ D C     G     CT ++   
Sbjct: 1347 SSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLDMCGFQ--GLQHLLCTHMSTMT 1403

Query: 1144 QACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWG 1202
              C + G  V  WR P  CP+ C    P  +    Y  C  PC  TC +           
Sbjct: 1404 TTCQDAGHAVKPWREPHFCPMACP---PNSK----YSLCAKPCPDTCHSGFSGMFCSDRC 1456

Query: 1203 LEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPR---CHVHGKSYRPG----AVVPSDK- 1254
            +E C  +C P    F    ++C+       L P      V  + Y+PG     V  S+  
Sbjct: 1457 VEAC--ECNPG---FVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNR 1511

Query: 1255 -NCQSCLC-------TERGVECTYKAEACVCTYNGQRFHPGDVIYHTTDG 1296
              CQ   C        + G+   +   A  CT +      GD  Y T DG
Sbjct: 1512 IRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTAS------GDPHYLTFDG 1555



 Score =  127 bits (318), Expect = 1e-28
 Identities = 134/567 (23%), Positives = 211/567 (37%), Gaps = 98/567 (17%)

Query: 776  VHDSGAICTCTHGKLS--------CIGGQAPAPVCAAPMVFFDCRNAT-------PGDTG 820
            V    +  +C HG+          C   QA A +CA        RN T       PG + 
Sbjct: 1759 VPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSY 1818

Query: 821  AGCQKSCHTLDMTCYSPQ-------CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYR 873
            + C   C     +  +P+       C   C C  G +  G   C+    C C     SY 
Sbjct: 1819 SPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS-CVPLGQCGCTDPAGSYH 1877

Query: 874  AGQTIRVGCNTCT--CDSRMWR---CTDDPC-------------------LATCAVYGDG 909
                     NTCT  C   +     C    C                   +  C + G+ 
Sbjct: 1878 PVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGES 1937

Query: 910  HYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLG 969
            HY++FDG ++S    C   LV+  C    +    F  ++        GT   +  ++++ 
Sbjct: 1938 HYVSFDGSNHSIPDACTLVLVKV-C--HPAMALPFFKISAKHEKEEGGTEAFRLHEVYID 1994

Query: 970  GFELKLSHGKVEVIGTDESQ-------EVP-YTIRQMGIYLVVDTDIGLVLLWDKKTSIF 1021
             ++ +++  K   +  +  Q       ++P  +++   IY +V+  IG+ + +D    + 
Sbjct: 1995 IYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLE 2054

Query: 1022 INLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWK---LSPSCPDALA-- 1076
            I +   + G+VCG+CGNF+D   ++    S  V     EF NSWK   + PSC   L   
Sbjct: 2055 IEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDE 2114

Query: 1077 ----------PKDPCTANPFRKSWAQKQC-SILHGPTFAACHAHVEPARYYEACVNDACA 1125
                      P   C A   R+  A+++C + L  P +A C + ++   +   C N    
Sbjct: 2115 QQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TL 2170

Query: 1126 CDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVP 1184
            C+ GG  +  C A+ A+   C   GL    WR  S CPL C  Y+        Y  C   
Sbjct: 2171 CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS-------SYTNCLPS 2223

Query: 1185 CLRTCRNPRGDC---LRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHG 1241
            C  +C +  G C          EGC   C P   +  EDK    + C           HG
Sbjct: 2224 CSPSCWDLDGRCEGAKVPSACAEGCI--CQP-GYVLSEDKCVPRSQCGCK------DAHG 2274

Query: 1242 KSYRPGAVVPSDKNCQSCLCTERGVEC 1268
             S   G    S    + C+CT   ++C
Sbjct: 2275 GSIPLGKSWVSSGCTEKCVCTGGAIQC 2301



 Score =  104 bits (260), Expect = 8e-22
 Identities = 94/362 (25%), Positives = 142/362 (39%), Gaps = 65/362 (17%)

Query: 823  CQKSCHTLDMTCYSPQ----CVPGCVCPDGLVADGEGGCITAEDCPC--VHNEASYRAGQ 876
            C  SC  LD  C   +    C  GC+C  G V   E  C+    C C   H  +      
Sbjct: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLS-EDKCVPRSQCGCKDAHGGSIPLGKS 2282

Query: 877  TIRVGCNT-CTCDSRMWRCTDDPCLA---------------------TCAVYGDGHYLTF 914
             +  GC   C C     +C D  C +                      C+VYGD  YLTF
Sbjct: 2283 WVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTF 2342

Query: 915  DGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELK 974
            DG SY   G   Y L++          +   V   N       +   + +   + G++++
Sbjct: 2343 DGFSYRLQGRMTYVLIKT-VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQ 2401

Query: 975  LSHGKVEVIGTDESQEVPY--------TIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSP 1026
            L  G +E++  ++   VPY        T+    +YLV  TD  LV+ +  + +  I+L  
Sbjct: 2402 LQAG-LELVVNNQKMAVPYRPNEHLRVTLWGQRLYLV--TDFELVVSFGGRKNAVISLPS 2458

Query: 1027 EFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPS-----CPDALAPKD-- 1079
             ++G V GLCGN+D    ND    S ++  ++  FGNSW++         P A+  ++  
Sbjct: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEG 2518

Query: 1080 --------------PCTANPFRKSWAQKQCSILHGP--TFAACHAHVEPARYYEACVNDA 1123
                           C+      +  Q  C +L  P   FAACH  V P  + E CV D 
Sbjct: 2519 QGAELGLRTGLQVSECSPEQLASNSTQ-ACRVLADPQGPFAACHQTVAPEPFQEHCVLDL 2577

Query: 1124 CA 1125
            C+
Sbjct: 2578 CS 2579



 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 85/355 (23%), Positives = 125/355 (35%), Gaps = 39/355 (10%)

Query: 1686 TVATTRPT---PHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRN 1742
            T+ + +PT     PT    + T  +  P+ STE+PT  +    T T  T  +   PV   
Sbjct: 620  TIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPT 679

Query: 1743 CHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPE-------------EITR 1789
              P     K      P+  P    +ET    I S EK    PE             E + 
Sbjct: 680  EKPSIPTEK---PSIPTEKPTISMEET----IISTEKPTISPEKPTIPTEKPTIPTEKST 732

Query: 1790 LQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPV 1849
            +     + P        +    S E+      +    P K+ +  E   +  E P   P 
Sbjct: 733  ISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPT-IPT 791

Query: 1850 TSTPVTA--PSTPSGRAISPTQSTS------SWQKSRTTTLVTTSTTSTPQTSTTYAHTT 1901
                ++   P+TP+      T+  S      +     TTT V  +T ST + +      T
Sbjct: 792  EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851

Query: 1902 STTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTS 1961
             +T  PT  T     +      P    + P   P+     +TIS    +I +   T +  
Sbjct: 852  ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911

Query: 1962 APTSSTTSAPT--TSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPG--TTPSPVPT 2012
             PT S T  PT  T   + PT  TT S  T   + PT   T  P   T P+  PT
Sbjct: 912  KPTIS-TEKPTIPTEKPTIPTEETTIS--TEKLTIPTEKPTISPEKLTIPTEKPT 963



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 52/178 (29%), Positives = 69/178 (38%), Gaps = 20/178 (11%)

Query: 1844 PRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST 1903
            P  CPV   P   P       +SP  ST     S TT L    T ST + + +    + T
Sbjct: 531  PGTCPVKVLPELPP-------VSPVSSTG---PSETTGLTENPTISTKKPTVSIEKPSVT 580

Query: 1904 TSAPTA--RTTSAPTTR-TTSASPASTTSGPGNTPSPVPT----TSTISAPTTSITSAPT 1956
            T  PT      + PT + T S    +  S   N PS  PT      TI     +I S   
Sbjct: 581  TEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKP 640

Query: 1957 TSTTSAPTSST--TSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPT 2012
            T  +  PT ST   + PT   T+ PT  TT+S +         S  +   + P+  PT
Sbjct: 641  TIPSEKPTISTEKPTVPTEEPTT-PTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPT 697



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 125/576 (21%), Positives = 205/576 (35%), Gaps = 93/576 (16%)

Query: 1478 PLACSTSSSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTF 1537
            P++  +S+ P++TT  T + T  T+    S    +  T   +  +  P   T  + K T 
Sbjct: 544  PVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKP---TIPTEKPTI 600

Query: 1538 STPSP-------------PPVPATSTSSMST--TTPGT--SVVSSKPTLTEPSTSSCLQE 1580
            ST  P             P +P+   + ++   T P    ++ S KPT++    +   +E
Sbjct: 601  STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE 660

Query: 1581 LCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQD 1640
              T TE    S   P I                   E P S+     S P        ++
Sbjct: 661  PTTPTEETTTSMEEPVIP-----------------TEKP-SIPTEKPSIPTEKPTISMEE 702

Query: 1641 VICSHTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPK--TVAT---TRP 1692
             I S  +  I   K  +P   P     +  I   +        T P +  T++    T P
Sbjct: 703  TIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP 762

Query: 1693 TPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPRCTWTKW 1752
            T  PT +  + T  T  P+  TE+PT  +   PT ++    T T   T +          
Sbjct: 763  TEKPTISPEKLTIPTEKPTIPTEKPTIPTEK-PTISTEEPTTPTEETTISTEKP------ 815

Query: 1753 FDVDFPSPGPHGGDKETYNNIIR---SGEKIC---RRPEEITRLQCRAKSHPEVSIEHLG 1806
                 P   P    +ET  ++     S EK+     +P   T         P +S E L 
Sbjct: 816  ---SIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKL- 871

Query: 1807 QVVQCSREEGLVCRNQDQQGPFK-MCLNYEVRVLCCETPRGCPVTSTPVTA-PSTPSGRA 1864
                    E L    +    P +   ++ E   +  E P   P   T  T  P+ P+ + 
Sbjct: 872  ----TIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKP 927

Query: 1865 ISPTQSTSSWQKSRTTTLVTTSTTSTPQTST--TYAHTTSTT--SAPTARTT------SA 1914
              PT+ T+    +   T+ T   T +P+  T  T   T ST   + PT + T      + 
Sbjct: 928  TIPTEETTI--STEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTI 985

Query: 1915 PTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTS 1974
            PT + T  +   T   P   P P PT + ++A   S           AP++  TS    +
Sbjct: 986  PTEKPTIPTEKLTALRP---PHPSPTATGLAALVMS---------PHAPSTPMTSVILGT 1033

Query: 1975 TTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPV 2010
            TT++ +S+    P     S    ++   P  +  P+
Sbjct: 1034 TTTSRSSTERCPPNARYESCACPASCKSPRPSCGPL 1069



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 75/326 (23%), Positives = 109/326 (33%), Gaps = 27/326 (8%)

Query: 1690 TRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPRCTW 1749
            T PT  PT +  + T  +  P+  +E+PT  S      T         P   +  P  + 
Sbjct: 592  TIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIST 651

Query: 1750 TKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVV 1809
             K      P+  P    +ET  ++          P   T         P +  E      
Sbjct: 652  EK---PTVPTEEPTTPTEETTTSM--------EEPVIPTEKPSIPTEKPSIPTEK----P 696

Query: 1810 QCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVT-STPVTAPSTPSGR-AISP 1867
              S EE ++   +    P K  +  E   +  E     P   +TP   P+ P+ +  ISP
Sbjct: 697  TISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISP 756

Query: 1868 TQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPAST 1927
             + T+  +K   +    T  T  P   T     T  T  PT  T    T    +      
Sbjct: 757  EKPTTPTEKPTISPEKLTIPTEKPTIPTE--KPTIPTEKPTISTEEPTTPTEETTISTEK 814

Query: 1928 TSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSP 1987
             S P   P+     +T S   T+I++   T     PT ST   PT      PT   T SP
Sbjct: 815  PSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEK-PTI-----PTEKPTISP 868

Query: 1988 QTSTTSAPTTSTTSGPGTTPSPVPTT 2013
            +  T   PT   T        P+  T
Sbjct: 869  EKLT--IPTEKLTIPTEKPTIPIEET 892



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 62/204 (30%), Positives = 77/204 (37%), Gaps = 40/204 (19%)

Query: 1848 PVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYA--HTTSTTS 1905
            PV+    T PS  +G   +PT ST     S     VTT   + P+   T      T +T 
Sbjct: 544  PVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTE 603

Query: 1906 APT--ARTTSAPTTRTT--SASPASTTSGPG------NTPSPVPTTSTISAPT--TSITS 1953
             PT  +   + P+ + T  S  P   T  P         PS  PT ST   PT  T   +
Sbjct: 604  KPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIST-EKPTVPTEEPT 662

Query: 1954 APTTSTT-------------SAPT---SSTTSAPTTST--TSAPTSSTTSSPQ-----TS 1990
             PT  TT             S PT   S  T  PT S   T   T   T SP+     T 
Sbjct: 663  TPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTE 722

Query: 1991 TTSAPTTSTTSGP--GTTPSPVPT 2012
              + PT  +T  P   TTP+  PT
Sbjct: 723  KPTIPTEKSTISPEKPTTPTEKPT 746


>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
          Length = 2721

 Score =  290 bits (741), Expect = 1e-77
 Identities = 232/803 (28%), Positives = 343/803 (42%), Gaps = 79/803 (9%)

Query: 73   NPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESA--- 129
            +P      C  +G  HY TFDG  F F G C Y+ ++ CG + + F     +++E     
Sbjct: 1148 HPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEG 1207

Query: 130  APTLSRVLMKVDGVVIQLTKGS-VLVNGHPVLLPFSQS-GVLIQQSSSYTKVEARLGLVL 187
               LS+V + +    + L KG   LV G  V LP   S GV +  S  + +++   GL +
Sbjct: 1208 VSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRV 1267

Query: 188  MWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSEL-LSHNTKLTPMEFGNLQKMD-DPT 245
             W+ D  L + + + Y+ K CGLCG+++G      L L  +      E GN  + D D  
Sbjct: 1268 RWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDED 1327

Query: 246  EQCQ--DPVPEPPRNCS-----TGFGICEELL--HGQLFSGCVALVDVGSYLEACRQDLC 296
            ++CQ    V  P  + S     +G G C  L+  HG  F  C+  V   S+ ++C  D+C
Sbjct: 1328 QECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLDMC 1386

Query: 297  FCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCS 356
              +    L  +C  ++  +  C  AG   + WR P FCP  CP N +Y  C  PC DTC 
Sbjct: 1387 GFQGLQHL--LCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH 1444

Query: 357  NQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAY--APGATYSTDCT 414
            +      C D CV  C C  G VL  +    C+P S+C C++   +Y       Y   C 
Sbjct: 1445 SGFSGMFCSDRCVEACECNPGFVLSGL---ECIPRSQCGCLHPAGSYFKVGERWYKPGCK 1501

Query: 415  N-CTC-SGGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVH 453
              C C S  R  CQ   C                     TC+  G  H+ TFDG  +   
Sbjct: 1502 ELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFM 1561

Query: 454  GDCSYVLTKPC----DSSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEV 509
            G C+YVLT+PC      S F V A     G     + +K+V +++  +   + +    +V
Sbjct: 1562 GTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLS--ISLLRGCKV 1619

Query: 510  FLNQIYTQLPI--SAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQT 567
             LN     LP+  +   VTI R S+  ++  T+ GLQ+       ++  + +     GQ 
Sbjct: 1620 MLNGHRVALPVWLAQGRVTI-RLSSNLVLLYTNFGLQVRYDGSHLVE--VTVPSSYGGQL 1676

Query: 568  CGLCGNFNSIQADD----FRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVEN 623
            CGLCGN+N+   DD     R L+G      AA+     ++  C  +          S + 
Sbjct: 1677 CGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGK-----PSSCQE 1731

Query: 624  EKYAQHW---CSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVH 680
               A  W   C+ L +  GPF +CH  V P + +++C+   C  +     LC +L +Y  
Sbjct: 1732 NSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYAS 1791

Query: 681  ACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDG 740
             CA  G Q   WR+     PM  CP   +Y    S C  TC S++     C       + 
Sbjct: 1792 LCAQAG-QAPAWRNRTFC-PM-RCPPGSSYSPCSSPCPDTCSSIN-NPRDCPKALPCAES 1847

Query: 741  CICPKGTFLDDTGKCVQASNCPCYH-RGSMIPNGESVHDSGA---ICTCT-HGKLSCIGG 795
            C C KG  L  T  CV    C C    GS  P GE  +       +CTC+ H  ++C   
Sbjct: 1848 CECQKGHILSGT-SCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQS 1906

Query: 796  QA-PAPVCAAPMVFFDCRNATPG 817
               P  +C A      CR +  G
Sbjct: 1907 TCKPNQICWALDGLLRCRASGVG 1929



 Score =  243 bits (619), Expect = 2e-63
 Identities = 212/793 (26%), Positives = 330/793 (41%), Gaps = 88/793 (11%)

Query: 75   AHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLS 134
            A     C+  G  HY TFDG +  F G C YV +  C +  +D    +  + E+    L 
Sbjct: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595

Query: 135  RVLMKVDGVV-----IQLTKG-SVLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLV 186
               +K   V      I L +G  V++NGH V LP   +Q  V I+ SS+   +    GL 
Sbjct: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655

Query: 187  LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMDDP 244
            + ++    + + + + Y  + CGLCG++N   +  + L  + KL    M+ G   K+ + 
Sbjct: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSL-DDNLRPDRKLAGDSMQLGAAWKLPES 1714

Query: 245  TEQCQDPVPEPPRNCSTGFGI------CEELLHGQ-LFSGCVALVDVGSYLEACRQDLCF 297
            +E     V   P +C            C  L++ Q  FS C  +V   S   +C    C 
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG 1774

Query: 298  CE-DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCS 356
             + DT  L   C +L  Y+  C  AG  P  WR   FCP +CP    Y  C SPC DTCS
Sbjct: 1775 TKGDTTAL---CRSLQAYASLCAQAGQAPA-WRNRTFCPMRCPPGSSYSPCSSPCPDTCS 1830

Query: 357  NQEHSRACEDH--CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP-GATYSTD- 412
            +  + R C     C   C C +G +L     T CVP+ +C C     +Y P G  + T+ 
Sbjct: 1831 SINNPRDCPKALPCAESCECQKGHILSG---TSCVPLGQCGCTDPAGSYHPVGERWYTEN 1887

Query: 413  -CTN-CTCS-GGRWSCQEVPCP-------------------GTCSVLGGAHFSTFDGKQY 450
             CT  CTCS     +C +  C                    G C + G +H+ +FDG  +
Sbjct: 1888 TCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNH 1947

Query: 451  TVHGDCSYVLTKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKAS 506
            ++   C+ VL K C  +     F + A+  +         L  V + +   Q  V ++  
Sbjct: 1948 SIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQ--VTLQKG 2005

Query: 507  GEVFLNQIYTQLP-ISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRG 565
              V +N     LP IS       + S+ + I    +G+Q+         L +++     G
Sbjct: 2006 HRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD--GNHLLEIEIPTTYYG 2063

Query: 566  QTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENEK 625
            + CG+CGNFN  + D+    S  V  + + F N++K +   P+ ++   D   +  E ++
Sbjct: 2064 KVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQE 2123

Query: 626  YAQHWCSQLTDADGPFGRCHAAVKPGT------------YYSNCMFDTCNCERSEDCLCA 673
                 C +  D      +C AA++               +  +C    C        LC 
Sbjct: 2124 NPSGNC-RAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQ 2182

Query: 674  ALSSYVHACAAKGVQLGGWRD-GVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCS 732
            AL ++   C ++G++   WR+   C      CP   +Y   + +C P+C  L   D  C 
Sbjct: 2183 ALQAFGATCQSQGLKPPLWRNSSFCP---LECPAYSSYTNCLPSCSPSCWDL---DGRCE 2236

Query: 733  VGFIP---VDGCICPKGTFLDDTGKCVQASNCPCYH-RGSMIPNGESVHDSGAI--CTCT 786
               +P    +GCIC  G  L +  KCV  S C C    G  IP G+S   SG    C CT
Sbjct: 2237 GAKVPSACAEGCICQPGYVLSE-DKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCT 2295

Query: 787  HGKLSCIGGQAPA 799
             G + C   + P+
Sbjct: 2296 GGAIQCGDFRCPS 2308



 Score =  209 bits (533), Expect = 2e-53
 Identities = 186/711 (26%), Positives = 275/711 (38%), Gaps = 100/711 (14%)

Query: 80   VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHC--GAAYEDFNIQLRRSQESA---APTLS 134
            VC   G  HY +FDG     P  C  V  + C    A   F I  +  +E     A  L 
Sbjct: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989

Query: 135  RVLMKVDGVVIQLTKGS-VLVNGHPVLLP-FSQ-SGVLIQQSSSYTKVEARLGLVLMWNH 191
             V + +    + L KG  VL+N   V LP  SQ  GV ++ SS Y+ V  ++G+ + ++ 
Sbjct: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049

Query: 192  DDSLLLELDTKYANKTCGLCGDFNGMPVVSELL-SHNTKLTPMEFGNLQKMDDPTEQCQD 250
            +  L +E+ T Y  K CG+CG+FN       ++ S     +  EF N  K  D    CQ 
Sbjct: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS 2109

Query: 251  PVPE-----------PPRNCSTGF-----GICEELLHGQLFSGCVALVDVGSYLEACRQD 294
             + +           P  NC           CE  L   +++ C + +D+  +L  C   
Sbjct: 2110 LLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANT 2169

Query: 295  LCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADT 354
            LC  E   L   +C  L  +   C   G  P  WR   FCP +CP    Y  C   C+ +
Sbjct: 2170 LC--EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPS 2227

Query: 355  CSNQE---HSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCAC--VYNGAAYAPGATY 409
            C + +           C  GC C  G VL    +  CVP S+C C   + G+     +  
Sbjct: 2228 CWDLDGRCEGAKVPSACAEGCICQPGYVL---SEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284

Query: 410  STDCT-NCTCSGGRWSCQEVPCPG---------------------TCSVLGGAHFSTFDG 447
            S+ CT  C C+GG   C +  CP                       CSV G   + TFDG
Sbjct: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344

Query: 448  KQYTVHGDCSYVLTKPCD---SSAFTVLAELR-RCGLTDSETCLKSVTLSLDGVQTVVVI 503
              Y + G  +YVL K  D        +L E R +     S   L+ V  ++ G +  V +
Sbjct: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYK--VQL 2402

Query: 504  KASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQL--NLQLVPTM----QLFM 557
            +A  E+ +N     +P        +RP+    +      L L  + +LV +        +
Sbjct: 2403 QAGLELVVNNQKMAVP--------YRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI 2454

Query: 558  QLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT--------------- 602
             L     G   GLCGN++  + +D    SG +      F N+++                
Sbjct: 2455 SLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPA 2514

Query: 603  ----QAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCM 658
                Q A   +R   +       +    +   C  L D  GPF  CH  V P  +  +C+
Sbjct: 2515 EEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574

Query: 659  FDTCNCE---RSEDCLCAALSSYVHACAAKGVQLGGWRD-GVCTKPMTTCP 705
             D C+ +     E+  C  LS Y   C   G  L GWRD  +C  P    P
Sbjct: 2575 LDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNP 2625



 Score =  180 bits (457), Expect = 1e-44
 Identities = 140/492 (28%), Positives = 207/492 (42%), Gaps = 54/492 (10%)

Query: 336  QKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCA 395
            ++CP N +Y  C  P +  C +   S  C   C  GC C  G +  D     C+  S C 
Sbjct: 1042 ERCPPNARYESCACPAS--CKSPRPS--CGPLCREGCVCNPGFLFSD---NHCIQASSCN 1094

Query: 396  CVYNGAAYAPGAT-YSTDCT-NCTC-SGGRWSCQEVPC--------------------PG 432
            C YN   Y PGA  +S +CT +C C  G R  CQ   C                      
Sbjct: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154

Query: 433  TCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSA---FTVLAELRRCGLTDSETCLKS 489
            TC V G  H+ TFDG+ +   G C+Y+L +PC +S    F V A+    G  +  +CL  
Sbjct: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG-QEGVSCLSK 1213

Query: 490  VTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQL 549
            V ++L    TV ++K    +   Q  T LP   +       S  F+  QT  GL++    
Sbjct: 1214 VYVTLP-ESTVTLLKGRRTLVGGQQVT-LPAIPSKGVFLGASGRFVELQTEFGLRVRWD- 1270

Query: 550  VPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT----QAA 605
                QL++ ++    G+ CGLCGN++    +D   L G          N+++T       
Sbjct: 1271 -GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQE 1329

Query: 606  CPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCE 665
            C   +      C  S+++      +C +L D  GPF  C   VK  +++ +CM D C  +
Sbjct: 1330 CQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389

Query: 666  RSEDCLCAALSSYVHACAAKGVQLGGWRD-GVCTKPMTTCPKSMTYHYHVSTCQPTCRSL 724
              +  LC  +S+    C   G  +  WR+   C  PM  CP +  Y      C  TC S 
Sbjct: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFC--PM-ACPPNSKYSLCAKPCPDTCHSG 1446

Query: 725  SEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYH-RGSMIPNGESVHDSGA-- 781
              G + CS     V+ C C  G  L    +C+  S C C H  GS    GE  +  G   
Sbjct: 1447 FSG-MFCSDRC--VEACECNPGFVLSGL-ECIPRSQCGCLHPAGSYFKVGERWYKPGCKE 1502

Query: 782  ICTC-THGKLSC 792
            +C C ++ ++ C
Sbjct: 1503 LCVCESNNRIRC 1514



 Score =  172 bits (436), Expect = 3e-42
 Identities = 132/426 (30%), Positives = 191/426 (44%), Gaps = 58/426 (13%)

Query: 823  CQKSCHT--LDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASY-RAGQT-I 878
            C  +CH+    M C S +CV  C C  G V  G   CI    C C+H   SY + G+   
Sbjct: 1439 CPDTCHSGFSGMFC-SDRCVEACECNPGFVLSGLE-CIPRSQCGCLHPAGSYFKVGERWY 1496

Query: 879  RVGCNT-CTCDS------RMWRC-TDDPC-------------LATCAVYGDGHYLTFDGQ 917
            + GC   C C+S      + WRC   + C              ATC   GD HYLTFDG 
Sbjct: 1497 KPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGA 1556

Query: 918  SYSFNGDCEYTLVQNHCGGKDSTQDSFRVV--TENVPCGTTGTTCSKAIKIFLGGFELKL 975
             + F G C Y L +  C  +  +QDS+ VV  T     G    +  KA+ + +    + L
Sbjct: 1557 LHHFMGTCTYVLTRP-CWSR--SQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISL 1613

Query: 976  SHG-KVEVIGTDESQEV-----PYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFK 1029
              G KV + G   +  V       TIR     +++ T+ GL + +D    + + +   + 
Sbjct: 1614 LRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYG 1673

Query: 1030 GRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL----SPSCPDALAPKDPCTANP 1085
            G++CGLCGN+++ +++D     R + GD ++ G +WKL     P C         C  N 
Sbjct: 1674 GQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENS 1733

Query: 1086 FRKSWAQKQCSILHGP--TFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYA 1143
               +W  K C+IL  P   F+ CH  V P   + +CV+  C   + GD    C ++ AYA
Sbjct: 1734 MADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG--TKGDTTALCRSLQAYA 1790

Query: 1144 QACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTC---RNPRGDCLRDV 1200
              C + G   +WR  + CP+ C    P G     Y PC  PC  TC    NPR DC + +
Sbjct: 1791 SLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSPCPDTCSSINNPR-DCPKAL 1842

Query: 1201 WGLEGC 1206
               E C
Sbjct: 1843 PCAESC 1848



 Score =  170 bits (431), Expect = 1e-41
 Identities = 149/530 (28%), Positives = 211/530 (39%), Gaps = 85/530 (16%)

Query: 823  CQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQT----- 877
            C  SC +   +C  P C  GCVC  G +   +  CI A  C C +N   Y  G       
Sbjct: 1055 CPASCKSPRPSC-GPLCREGCVCNPGFLFS-DNHCIQASSCNCFYNNDYYEPGAEWFSPN 1112

Query: 878  ----------IRVGCNTCTCDSR--------MWRCTDDPCLATCAVYGDGHYLTFDGQSY 919
                       RV C    C +          + C      ATC VYGD HY+TFDG+ +
Sbjct: 1113 CTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHF 1172

Query: 920  SFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGK 979
             F G C Y L Q  CG  +ST   FRV  +N   G  G +C   + + L    + L  G+
Sbjct: 1173 GFMGKCTYILAQP-CG--NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR 1229

Query: 980  VEVIGTDESQEVPY-TIRQMGIYL-------VVDTDIGLVLLWDKKTSIFINLSPEFKGR 1031
              ++G    Q+V    I   G++L        + T+ GL + WD    +++ +S  + G+
Sbjct: 1230 RTLVG---GQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGK 1286

Query: 1032 VCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL----SPSCPDALAPKDPCTANPFR 1087
            +CGLCGN+D  + ND      S  GD  E GNSW+        C        P   +  +
Sbjct: 1287 LCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQ 1346

Query: 1088 KSWAQKQ-CSIL---HGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYA 1143
             S +    C  L   HGP F  C  HV+ A ++++C+ D C     G     CT ++   
Sbjct: 1347 SSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLDMCGFQ--GLQHLLCTHMSTMT 1403

Query: 1144 QACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWG 1202
              C + G  V  WR P  CP+ C    P  +    Y  C  PC  TC +           
Sbjct: 1404 TTCQDAGHAVKPWREPHFCPMACP---PNSK----YSLCAKPCPDTCHSGFSGMFCSDRC 1456

Query: 1203 LEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPR---CHVHGKSYRPG----AVVPSDK- 1254
            +E C  +C P    F    ++C+       L P      V  + Y+PG     V  S+  
Sbjct: 1457 VEAC--ECNPG---FVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNR 1511

Query: 1255 -NCQSCLC-------TERGVECTYKAEACVCTYNGQRFHPGDVIYHTTDG 1296
              CQ   C        + G+   +   A  CT +      GD  Y T DG
Sbjct: 1512 IRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTAS------GDPHYLTFDG 1555



 Score =  127 bits (318), Expect = 1e-28
 Identities = 134/567 (23%), Positives = 211/567 (37%), Gaps = 98/567 (17%)

Query: 776  VHDSGAICTCTHGKLS--------CIGGQAPAPVCAAPMVFFDCRNAT-------PGDTG 820
            V    +  +C HG+          C   QA A +CA        RN T       PG + 
Sbjct: 1759 VPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSY 1818

Query: 821  AGCQKSCHTLDMTCYSPQ-------CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYR 873
            + C   C     +  +P+       C   C C  G +  G   C+    C C     SY 
Sbjct: 1819 SPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS-CVPLGQCGCTDPAGSYH 1877

Query: 874  AGQTIRVGCNTCT--CDSRMWR---CTDDPC-------------------LATCAVYGDG 909
                     NTCT  C   +     C    C                   +  C + G+ 
Sbjct: 1878 PVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGES 1937

Query: 910  HYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLG 969
            HY++FDG ++S    C   LV+  C    +    F  ++        GT   +  ++++ 
Sbjct: 1938 HYVSFDGSNHSIPDACTLVLVKV-C--HPAMALPFFKISAKHEKEEGGTEAFRLHEVYID 1994

Query: 970  GFELKLSHGKVEVIGTDESQ-------EVP-YTIRQMGIYLVVDTDIGLVLLWDKKTSIF 1021
             ++ +++  K   +  +  Q       ++P  +++   IY +V+  IG+ + +D    + 
Sbjct: 1995 IYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLE 2054

Query: 1022 INLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWK---LSPSCPDALA-- 1076
            I +   + G+VCG+CGNF+D   ++    S  V     EF NSWK   + PSC   L   
Sbjct: 2055 IEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDE 2114

Query: 1077 ----------PKDPCTANPFRKSWAQKQC-SILHGPTFAACHAHVEPARYYEACVNDACA 1125
                      P   C A   R+  A+++C + L  P +A C + ++   +   C N    
Sbjct: 2115 QQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TL 2170

Query: 1126 CDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVP 1184
            C+ GG  +  C A+ A+   C   GL    WR  S CPL C  Y+        Y  C   
Sbjct: 2171 CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS-------SYTNCLPS 2223

Query: 1185 CLRTCRNPRGDC---LRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHG 1241
            C  +C +  G C          EGC   C P   +  EDK    + C           HG
Sbjct: 2224 CSPSCWDLDGRCEGAKVPSACAEGCI--CQP-GYVLSEDKCVPRSQCGCK------DAHG 2274

Query: 1242 KSYRPGAVVPSDKNCQSCLCTERGVEC 1268
             S   G    S    + C+CT   ++C
Sbjct: 2275 GSIPLGKSWVSSGCTEKCVCTGGAIQC 2301



 Score =  122 bits (306), Expect = 4e-27
 Identities = 112/416 (26%), Positives = 166/416 (39%), Gaps = 71/416 (17%)

Query: 823  CQKSCHTLDMTCYSPQ----CVPGCVCPDGLVADGEGGCITAEDCPC--VHNEASYRAGQ 876
            C  SC  LD  C   +    C  GC+C  G V   E  C+    C C   H  +      
Sbjct: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLS-EDKCVPRSQCGCKDAHGGSIPLGKS 2282

Query: 877  TIRVGCNT-CTCDSRMWRCTDDPCLA---------------------TCAVYGDGHYLTF 914
             +  GC   C C     +C D  C +                      C+VYGD  YLTF
Sbjct: 2283 WVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTF 2342

Query: 915  DGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELK 974
            DG SY   G   Y L++          +   V   N       +   + +   + G++++
Sbjct: 2343 DGFSYRLQGRMTYVLIKT-VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQ 2401

Query: 975  LSHGKVEVIGTDESQEVPY--------TIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSP 1026
            L  G +E++  ++   VPY        T+    +YLV  TD  LV+ +  + +  I+L  
Sbjct: 2402 LQAG-LELVVNNQKMAVPYRPNEHLRVTLWGQRLYLV--TDFELVVSFGGRKNAVISLPS 2458

Query: 1027 EFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPS-----CPDALAPKD-- 1079
             ++G V GLCGN+D    ND    S ++  ++  FGNSW++         P A+  ++  
Sbjct: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEG 2518

Query: 1080 --------------PCTANPFRKSWAQKQCSILHGP--TFAACHAHVEPARYYEACVNDA 1123
                           C+      +  Q  C +L  P   FAACH  V P  + E CV D 
Sbjct: 2519 QGAELGLRTGLQVSECSPEQLASNSTQ-ACRVLADPQGPFAACHQTVAPEPFQEHCVLDL 2577

Query: 1124 C-ACDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTPSICPLFCDYYNP---EGQC 1174
            C A D     E  C  ++ YA  C E G  ++ WR  ++C   C   NP   +GQC
Sbjct: 2578 CSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC-LQNPCQNDGQC 2632



 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 85/355 (23%), Positives = 125/355 (35%), Gaps = 39/355 (10%)

Query: 1686 TVATTRPT---PHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRN 1742
            T+ + +PT     PT    + T  +  P+ STE+PT  +    T T  T  +   PV   
Sbjct: 620  TIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPT 679

Query: 1743 CHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPE-------------EITR 1789
              P     K      P+  P    +ET    I S EK    PE             E + 
Sbjct: 680  EKPSIPTEK---PSIPTEKPTISMEET----IISTEKPTISPEKPTIPTEKPTIPTEKST 732

Query: 1790 LQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPV 1849
            +     + P        +    S E+      +    P K+ +  E   +  E P   P 
Sbjct: 733  ISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPT-IPT 791

Query: 1850 TSTPVTA--PSTPSGRAISPTQSTS------SWQKSRTTTLVTTSTTSTPQTSTTYAHTT 1901
                ++   P+TP+      T+  S      +     TTT V  +T ST + +      T
Sbjct: 792  EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851

Query: 1902 STTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTS 1961
             +T  PT  T     +      P    + P   P+     +TIS    +I +   T +  
Sbjct: 852  ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911

Query: 1962 APTSSTTSAPT--TSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPG--TTPSPVPT 2012
             PT S T  PT  T   + PT  TT S  T   + PT   T  P   T P+  PT
Sbjct: 912  KPTIS-TEKPTIPTEKPTIPTEETTIS--TEKLTIPTEKPTISPEKLTIPTEKPT 963



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 52/178 (29%), Positives = 69/178 (38%), Gaps = 20/178 (11%)

Query: 1844 PRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST 1903
            P  CPV   P   P       +SP  ST     S TT L    T ST + + +    + T
Sbjct: 531  PGTCPVKVLPELPP-------VSPVSSTG---PSETTGLTENPTISTKKPTVSIEKPSVT 580

Query: 1904 TSAPTA--RTTSAPTTR-TTSASPASTTSGPGNTPSPVPT----TSTISAPTTSITSAPT 1956
            T  PT      + PT + T S    +  S   N PS  PT      TI     +I S   
Sbjct: 581  TEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKP 640

Query: 1957 TSTTSAPTSST--TSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPT 2012
            T  +  PT ST   + PT   T+ PT  TT+S +         S  +   + P+  PT
Sbjct: 641  TIPSEKPTISTEKPTVPTEEPTT-PTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPT 697



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 125/576 (21%), Positives = 205/576 (35%), Gaps = 93/576 (16%)

Query: 1478 PLACSTSSSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTF 1537
            P++  +S+ P++TT  T + T  T+    S    +  T   +  +  P   T  + K T 
Sbjct: 544  PVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKP---TIPTEKPTI 600

Query: 1538 STPSP-------------PPVPATSTSSMST--TTPGT--SVVSSKPTLTEPSTSSCLQE 1580
            ST  P             P +P+   + ++   T P    ++ S KPT++    +   +E
Sbjct: 601  STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE 660

Query: 1581 LCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQD 1640
              T TE    S   P I                   E P S+     S P        ++
Sbjct: 661  PTTPTEETTTSMEEPVIP-----------------TEKP-SIPTEKPSIPTEKPTISMEE 702

Query: 1641 VICSHTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPK--TVAT---TRP 1692
             I S  +  I   K  +P   P     +  I   +        T P +  T++    T P
Sbjct: 703  TIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP 762

Query: 1693 TPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPRCTWTKW 1752
            T  PT +  + T  T  P+  TE+PT  +   PT ++    T T   T +          
Sbjct: 763  TEKPTISPEKLTIPTEKPTIPTEKPTIPTEK-PTISTEEPTTPTEETTISTEKP------ 815

Query: 1753 FDVDFPSPGPHGGDKETYNNIIR---SGEKIC---RRPEEITRLQCRAKSHPEVSIEHLG 1806
                 P   P    +ET  ++     S EK+     +P   T         P +S E L 
Sbjct: 816  ---SIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKL- 871

Query: 1807 QVVQCSREEGLVCRNQDQQGPFK-MCLNYEVRVLCCETPRGCPVTSTPVTA-PSTPSGRA 1864
                    E L    +    P +   ++ E   +  E P   P   T  T  P+ P+ + 
Sbjct: 872  ----TIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKP 927

Query: 1865 ISPTQSTSSWQKSRTTTLVTTSTTSTPQTST--TYAHTTSTT--SAPTARTT------SA 1914
              PT+ T+    +   T+ T   T +P+  T  T   T ST   + PT + T      + 
Sbjct: 928  TIPTEETTI--STEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTI 985

Query: 1915 PTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTS 1974
            PT + T  +   T   P   P P PT + ++A   S           AP++  TS    +
Sbjct: 986  PTEKPTIPTEKLTALRP---PHPSPTATGLAALVMS---------PHAPSTPMTSVILGT 1033

Query: 1975 TTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPV 2010
            TT++ +S+    P     S    ++   P  +  P+
Sbjct: 1034 TTTSRSSTERCPPNARYESCACPASCKSPRPSCGPL 1069



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 75/326 (23%), Positives = 109/326 (33%), Gaps = 27/326 (8%)

Query: 1690 TRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPRCTW 1749
            T PT  PT +  + T  +  P+  +E+PT  S      T         P   +  P  + 
Sbjct: 592  TIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIST 651

Query: 1750 TKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVV 1809
             K      P+  P    +ET  ++          P   T         P +  E      
Sbjct: 652  EK---PTVPTEEPTTPTEETTTSM--------EEPVIPTEKPSIPTEKPSIPTEK----P 696

Query: 1810 QCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVT-STPVTAPSTPSGR-AISP 1867
              S EE ++   +    P K  +  E   +  E     P   +TP   P+ P+ +  ISP
Sbjct: 697  TISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISP 756

Query: 1868 TQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPAST 1927
             + T+  +K   +    T  T  P   T     T  T  PT  T    T    +      
Sbjct: 757  EKPTTPTEKPTISPEKLTIPTEKPTIPTE--KPTIPTEKPTISTEEPTTPTEETTISTEK 814

Query: 1928 TSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSP 1987
             S P   P+     +T S   T+I++   T     PT ST   PT      PT   T SP
Sbjct: 815  PSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEK-PTI-----PTEKPTISP 868

Query: 1988 QTSTTSAPTTSTTSGPGTTPSPVPTT 2013
            +  T   PT   T        P+  T
Sbjct: 869  EKLT--IPTEKLTIPTEKPTIPIEET 892



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 62/204 (30%), Positives = 77/204 (37%), Gaps = 40/204 (19%)

Query: 1848 PVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYA--HTTSTTS 1905
            PV+    T PS  +G   +PT ST     S     VTT   + P+   T      T +T 
Sbjct: 544  PVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTE 603

Query: 1906 APT--ARTTSAPTTRTT--SASPASTTSGPG------NTPSPVPTTSTISAPT--TSITS 1953
             PT  +   + P+ + T  S  P   T  P         PS  PT ST   PT  T   +
Sbjct: 604  KPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIST-EKPTVPTEEPT 662

Query: 1954 APTTSTT-------------SAPT---SSTTSAPTTST--TSAPTSSTTSSPQ-----TS 1990
             PT  TT             S PT   S  T  PT S   T   T   T SP+     T 
Sbjct: 663  TPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTE 722

Query: 1991 TTSAPTTSTTSGP--GTTPSPVPT 2012
              + PT  +T  P   TTP+  PT
Sbjct: 723  KPTIPTEKSTISPEKPTTPTEKPT 746


>gi|239755460 PREDICTED: similar to mucin, partial [Homo sapiens]
          Length = 1064

 Score =  277 bits (709), Expect = 7e-74
 Identities = 141/217 (64%), Positives = 160/217 (73%), Gaps = 7/217 (3%)

Query: 1687 VATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPR 1746
            V TT  T  PT + T    TT  P  +T   T  S+   +  SV++ TH+ PVT +CHP 
Sbjct: 46   VPTTSTTSAPTTSTTSGPGTTPSPVPTTST-TPVSKTSTSHLSVSKTTHSQPVTSDCHPL 104

Query: 1747 CTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLG 1806
            C WTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRA+SHPEV+IEHLG
Sbjct: 105  CAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIEHLG 164

Query: 1807 QVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAIS 1866
            QVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTS  VT   T    A+ 
Sbjct: 165  QVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTS--VTPYGTSPTNALY 222

Query: 1867 PTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST 1903
            P+ STS    S    + +TS  S+   S++ A++T T
Sbjct: 223  PSLSTSMVSAS----VASTSVASSSVASSSVAYSTQT 255



 Score =  141 bits (355), Expect = 7e-33
 Identities = 93/234 (39%), Positives = 121/234 (51%), Gaps = 29/234 (12%)

Query: 1509 PSSTPGTVSLSTARTTPAPGTATSVKKTFSTPSPPPVPATSTSSMSTTTPGTSVVS-SKP 1567
            P  T  T S  T  TT  PGT           +P PVP TST+ +S T+  TS +S SK 
Sbjct: 45   PVPTTSTTSAPTTSTTSGPGT-----------TPSPVPTTSTTPVSKTS--TSHLSVSKT 91

Query: 1568 TLTEPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSV---QC 1624
            T ++P TS C   LC WT+W D  +P+PG +GGD +T+ N+   G   C  P  +   QC
Sbjct: 92   THSQPVTSDC-HPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQC 150

Query: 1625 RAESFPNTPLADLGQDVICSHTEGLICLNKNQLPP--ICYNYEIRIQCCETVNVCRDITR 1682
            RAES P   +  LGQ V CS  EGL+C N++Q  P  +C NYE+R+ CCET   C     
Sbjct: 151  RAESHPEVNIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGC----- 205

Query: 1683 PPKTVATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHT 1736
             P T  T   T  PT A    + +T M SAS    T+ +     ++SV   T T
Sbjct: 206  -PVTSVTPYGT-SPTNA-LYPSLSTSMVSASVAS-TSVASSSVASSSVAYSTQT 255



 Score =  112 bits (281), Expect = 3e-24
 Identities = 72/214 (33%), Positives = 100/214 (46%), Gaps = 13/214 (6%)

Query: 1326 PTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPPV--C 1383
            PTT + S P    S+T  P   PS     P +S  P +  ++    +   + S P    C
Sbjct: 47   PTTSTTSAP--TTSTTSGPGTTPSPV---PTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101

Query: 1384 GEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSV---ECRAEDAPGVPLR 1440
               C W+ W DV  P  G   GD +T  N+   G ++C  P  +   +CRAE  P V + 
Sbjct: 102  HPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIE 161

Query: 1441 ALGQRVQCSPDVGLTCRNREQAS--GLCYNYQIRVQCC-TPLACSTSSSPAQTTPPTTSK 1497
             LGQ VQCS + GL CRN++Q     +C NY++RV CC TP  C  +S     T PT + 
Sbjct: 162  HLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVTPYGTSPTNAL 221

Query: 1498 TTETRASGSSAPSSTPGTVSLSTARTTPAPGTAT 1531
                  S  SA  ++    S S A ++ A  T T
Sbjct: 222  YPSLSTSMVSASVASTSVASSSVASSSVAYSTQT 255



 Score =  108 bits (269), Expect = 7e-23
 Identities = 139/611 (22%), Positives = 212/611 (34%), Gaps = 113/611 (18%)

Query: 696  VCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKC 755
            +C +    CP +    Y  S       SLS   ++ SV    V        +    T  C
Sbjct: 197  LCCETPRGCPVTSVTPYGTSPTNALYPSLSTSMVSASVASTSVASSSVASSSVAYSTQTC 256

Query: 756  VQASNCPCYHRGSMIPNGESV--HDSGAICT------------CTHGKLSCIGGQAPAPV 801
                    Y  GS I     +  H   A+C+            C    L      +P+  
Sbjct: 257  FCNVADRLYPAGSTIYRHRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSPSIS 316

Query: 802  CAAPMVFFDCRNATP----GDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGC 857
             + P+    C NA P    G+T A              +P C       + +++     C
Sbjct: 317  TSEPVTELGCPNAVPPRKKGETWA--------------TPNCSEATCEGNNVISLRPRTC 362

Query: 858  ITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQ 917
               E   C +   + +     + GC           C    C   C+ +GD HY+TFDG 
Sbjct: 363  PRVEKPTCANGYPAVKVAD--QDGC-----------CHHYQCQCVCSGWGDPHYITFDGT 409

Query: 918  SYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTT-GTTCSKAIKIFLGGFELKLS 976
             Y+F  +C Y LVQ            FRV+ +N  CG   G +C ++I +      + L+
Sbjct: 410  YYTFLDNCTYVLVQQIV----PVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLT 465

Query: 977  HGKVEVIGTDE----SQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRV 1032
               V  + T+E    ++ V    R+ GI   V + IG+ +     T   + +   F G +
Sbjct: 466  RKPVHGVMTNEIIFNNKVVSPGFRKNGI---VVSRIGVKMY---ATIPELGVQVMFSGLI 519

Query: 1033 CGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQ 1092
              +     ++  + FA  +              +          P  PC  +P       
Sbjct: 520  FSV-----EVPFSKFANNTEG------------QCXXXXXXXTTPPAPCLPSPI------ 556

Query: 1093 KQCSILHGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLC 1152
              C ++    F  CH  + P  +YE CV D C      D +  C+++  YA  C    +C
Sbjct: 557  --CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMT---DLDVVCSSLELYAALCASHDIC 611

Query: 1153 VSW--RTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWG----LEGC 1206
            + W  RT  +CP  C         +  YQPCG      C       L  +       EGC
Sbjct: 612  IDWRGRTGHMCPFTC-------PADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGC 664

Query: 1207 YPKCPPEAPIFDEDKMQCVAT-CPTPPLPPRC-HVHGKSYRPGAVVPSDKNCQSCLCTER 1264
            +  CP    +F      CV T C      PRC   HG+  + G  V  D  CQ C C   
Sbjct: 665  F--CPEGMTLFSTSAQVCVPTGC------PRCLGPHGEPVKVGHTVGMD--CQECTCEAA 714

Query: 1265 GVECTYKAEAC 1275
                T + + C
Sbjct: 715  TWTLTCRPKLC 725



 Score =  106 bits (265), Expect = 2e-22
 Identities = 135/538 (25%), Positives = 199/538 (36%), Gaps = 89/538 (16%)

Query: 425 CQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDS--SAFTVLAELRRCGLTD 482
           C    C   CS  G  H+ TFDG  YT   +C+YVL +        F VL +   CG  D
Sbjct: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445

Query: 483 SETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLG 542
             +C +S+ L     + V+  K    V  N+I     + +     FR +   +   + +G
Sbjct: 446 GLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPG---FRKNGIVV---SRIG 499

Query: 543 LQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT 602
           +++   +           P+L  Q               F  L   VE   + F N   T
Sbjct: 500 VKMYATI-----------PELGVQVM-------------FSGLIFSVEVPFSKFANN--T 533

Query: 603 QAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTC 662
           +  C         P +  + +    Q   S++      F  CH  + P  +Y  C+FD C
Sbjct: 534 EGQCXXXXXXXTTPPAPCLPSP-ICQLILSKV------FEPCHTVIPPLLFYEGCVFDRC 586

Query: 663 NCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCR 722
           +     D +C++L  Y   CA+  + +  WR         TCP    Y      C P+  
Sbjct: 587 HM-TDLDVVCSSLELYAALCASHDICI-DWRGRTGHMCPFTCPADKVY----QPCGPSNP 640

Query: 723 SLSEGDITCSVGFIP-----VDGCICPKG-TFLDDTGKCVQASNCP-CY-HRGSMIPNGE 774
           S   G+ + S+G +P      +GC CP+G T    + +    + CP C    G  +  G 
Sbjct: 641 SYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGH 700

Query: 775 SVHDSGAICTCTHG--KLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGC-QKSCHTLD 831
           +V      CTC      L+C     P P  A P+  F    A P   G  C Q SC    
Sbjct: 701 TVGMDCQECTCEAATWTLTCRPKLCPLPP-ACPLPGFVPVPAAP-QAGQCCPQYSC---- 754

Query: 832 MTCYSPQCVPGCVCPDG---LVADGEGGCITAEDCP---CVHNEASYRAGQTIRVG-CNT 884
             C + +C     CP+G   +    EG C   ++C    C  N   Y+ G  +    C T
Sbjct: 755 -ACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCET 813

Query: 885 CTC--------DSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHC 934
           C C        D+ +  C    C   C V        F+ Q  S  G C  T VQ  C
Sbjct: 814 CRCELPGGPPSDAFVVSCETQICNTHCPV-------GFEYQEQS--GQCCGTCVQVAC 862



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 94/377 (24%), Positives = 140/377 (37%), Gaps = 69/377 (18%)

Query: 80  VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLS---RV 136
           VCS WG  HY TFDG  + F   C YV  +     Y  F + +      A   LS    +
Sbjct: 394 VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453

Query: 137 LMKVDGVVIQLTK--------GSVLVNGHPVLLPFSQSGVLIQQSS--SYTKVEARLGLV 186
           +++     + LT+          ++ N   V   F ++G+++ +     Y  +   LG+ 
Sbjct: 454 ILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATIP-ELGVQ 512

Query: 187 LMWNHDDSLLLELD---TKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDD 243
           +M++    L+  ++   +K+AN T G C                                
Sbjct: 513 VMFS---GLIFSVEVPFSKFANNTEGQCXXXXXXXTT----------------------- 546

Query: 244 PTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303
           P   C   +P P         IC+ +L  ++F  C  ++    + E C  D C   D D+
Sbjct: 547 PPAPC---LPSP---------ICQLIL-SKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDV 593

Query: 304 LSCVCHTLAEYSRQCTHAGGLPQDWRGPD--FCPQKCPNNMQYHECRSPCADTC-SNQEH 360
              VC +L  Y+  C  +  +  DWRG     CP  CP +  Y  C       C  N   
Sbjct: 594 ---VCSSLELYAALCA-SHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSA 649

Query: 361 SRACEDHC---VAGCFCPEGTVLDDIGQTGCVPVSKCACV-YNGAAYAPGATYSTDCTNC 416
           S            GCFCPEG  L       CVP     C+  +G     G T   DC  C
Sbjct: 650 SLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQEC 709

Query: 417 TCSGGRW--SCQEVPCP 431
           TC    W  +C+   CP
Sbjct: 710 TCEAATWTLTCRPKLCP 726



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 35/76 (46%), Positives = 42/76 (55%), Gaps = 1/76 (1%)

Query: 1937 PVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPT 1996
            PVPTTST SAPTTS TS P T+ +  PT+STT    TST+    S TT S   ++   P 
Sbjct: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPL 104

Query: 1997 TSTTSGPGTT-PSPVP 2011
             + T       PSP P
Sbjct: 105  CAWTKWFDVDFPSPGP 120



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 31/53 (58%), Positives = 34/53 (64%), Gaps = 1/53 (1%)

Query: 1915 PTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTT-SAPTSS 1966
            PTT TTSA   STTSGPG TPSPVPTTST     TS +    + TT S P +S
Sbjct: 47   PTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTS 99



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 26/27 (96%), Positives = 26/27 (96%)

Query: 1987 PQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
            P TSTTSAPTTSTTSGPGTTPSPVPTT
Sbjct: 47   PTTSTTSAPTTSTTSGPGTTPSPVPTT 73



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 27/57 (47%), Positives = 36/57 (63%)

Query: 1950 SITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTT 2006
            ++   PTTSTTSAPT+STTS P T+ +  PT+STT   +TST+    + TT     T
Sbjct: 42   NLCPVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVT 98



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 46/146 (31%), Positives = 54/146 (36%), Gaps = 17/146 (11%)

Query: 307 VCHTLAEYSRQCTHAGGLPQDWRGPDFCP--QKCPNNMQYHECRSPCADTCSNQEHSRAC 364
           V HT+    ++CT           P  CP    CP         +P A  C  Q +S AC
Sbjct: 698 VGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPLPGFVPVPAAPQAGQCCPQ-YSCAC 756

Query: 365 E-DHCVAGCFCPEGTVLDDIGQTG-CVPVSKCA---CVYNGAAYAPGATYSTD-CTNCTC 418
               C     CPEG       Q G C PV  C+   C  NG  Y PGA  S+  C  C C
Sbjct: 757 NTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRC 816

Query: 419 S--GGR------WSCQEVPCPGTCSV 436
              GG        SC+   C   C V
Sbjct: 817 ELPGGPPSDAFVVSCETQICNTHCPV 842



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 25/53 (47%), Positives = 27/53 (50%), Gaps = 1/53 (1%)

Query: 1891 PQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTS-GPGNTPSPVPTTS 1942
            P TSTT A TTSTTS P    +  PTT TT  S  ST+      T    P TS
Sbjct: 47   PTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTS 99



 Score = 40.0 bits (92), Expect = 0.023
 Identities = 30/129 (23%), Positives = 43/129 (33%), Gaps = 18/129 (13%)

Query: 1270 YKAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTF 1329
            Y  + C C    + +  G  IY   D  G C  A C  +  + R V    P+T +PP   
Sbjct: 251  YSTQTCFCNVADRLYPAGSTIYRHRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLPPA-- 308

Query: 1330 SFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPT----------------TAGTSPRTRLP 1373
              ++P +  S   T    P++         W T                   T PR   P
Sbjct: 309  PATSPSISTSEPVTELGCPNAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCPRVEKP 368

Query: 1374 TASASLPPV 1382
            T +   P V
Sbjct: 369  TCANGYPAV 377



 Score = 39.7 bits (91), Expect = 0.030
 Identities = 21/45 (46%), Positives = 25/45 (55%)

Query: 1884 TTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTT 1928
            TTSTTS P TSTT    T+ +  PT  TT    T T+  S + TT
Sbjct: 48   TTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTT 92



 Score = 38.5 bits (88), Expect = 0.067
 Identities = 20/53 (37%), Positives = 29/53 (54%)

Query: 1879 TTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931
            TT+  TTSTTS P T+ +   TTSTT      T+    ++TT + P ++   P
Sbjct: 51   TTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHP 103



 Score = 36.2 bits (82), Expect = 0.33
 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 1/74 (1%)

Query: 1867 PTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTT-SAPTTRTTSASPA 1925
            PT ST+S   + TT+   T+ +  P TSTT    TST+    ++TT S P T       A
Sbjct: 47   PTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPLCA 106

Query: 1926 STTSGPGNTPSPVP 1939
             T     + PSP P
Sbjct: 107  WTKWFDVDFPSPGP 120


>gi|134268640 tectorin alpha precursor [Homo sapiens]
          Length = 2155

 Score =  231 bits (589), Expect = 5e-60
 Identities = 195/733 (26%), Positives = 300/733 (40%), Gaps = 80/733 (10%)

Query: 91   TFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSRVL--------MKVDG 142
            TFDG  + FP   +Y   + C    E   I + + +  A P   R L        +K+ G
Sbjct: 723  TFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGG 782

Query: 143  VVIQLTKGSVLVNGHPVLLPFSQ-SGVL-IQQSSSYTKVEARLGLVLMWNHDDSLLLELD 200
            +        V +NG  V LPF   SG L I ++ + T VE++  + + ++    L + L 
Sbjct: 783  I----GASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLS 838

Query: 201  TKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDDPTEQCQDPVPEPPRNCS 260
            T Y N T GLCG +N      E    N K T      L+      E C     +  + C+
Sbjct: 839  TTYFNCTGGLCGFYNAN-ASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACN 897

Query: 261  TGF------------GICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVC 308
                           GI  +  +   F  C  +V+V +Y   C   LC     +  S +C
Sbjct: 898  NDSELLKFYRSRSRCGIINDPSNSS-FLECHGVVNVTAYYRTCLFRLCQSGGNE--SELC 954

Query: 309  HTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHC 368
             ++A Y+  C +A      WR  DFCP +CP N  + EC + C +TC        C D C
Sbjct: 955  DSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECIT-CTETCETLTLGPICVDSC 1013

Query: 369  VAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTCSG--GRW 423
              GC C EG  L  +G   CV  S+C C + G   A   T+    DC   C CSG   R 
Sbjct: 1014 SEGCQCDEGYAL--LGSQ-CVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRV 1070

Query: 424  SCQEVPCP-------------------GTCSVLGGAHFSTFDGKQYTVHGDCSYVL---- 460
             C+ +PC                     +C V G  H+ TFDG  +     C  +L    
Sbjct: 1071 HCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTG 1130

Query: 461  TKPCDSSAFTVLAELRRCGLTDSETCL--KSVTLSLDGVQTVVVIKASGEVFLN--QIYT 516
            ++P  S +F       +    D    L  K V +++ G   V+       V +N  ++Y 
Sbjct: 1131 SRP-SSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYL 1189

Query: 517  QLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAP--KLRGQTCGLCGNF 574
             L +    + IF    F ++ +T  GL++    V   + F+ +     ++  T GLCG +
Sbjct: 1190 PLKLGQGKINIFSFG-FHVVVETDFGLKV----VYDWKTFLSITVPRSMQNSTYGLCGRY 1244

Query: 575  NSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQL 634
            N    DD     G++ ++   F  ++  +     +      P    VE     Q  CS +
Sbjct: 1245 NGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLI 1304

Query: 635  TDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRD 694
             + +  F +CH+ V P  +Y NC+FD+C    +    C+ L +Y   C  +G+ + GWR+
Sbjct: 1305 PNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRN 1364

Query: 695  GVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGK 754
               T    TCP +  Y   VS CQP C ++    +        V+GC C  G  L+    
Sbjct: 1365 --YTSCTVTCPPNSHYESCVSVCQPRCAAIR---LKSDCSHYCVEGCHCDAGYVLNGK-S 1418

Query: 755  CVQASNCPCYHRG 767
            C+   +C CY  G
Sbjct: 1419 CILPHSCGCYSDG 1431



 Score =  229 bits (583), Expect = 3e-59
 Identities = 205/779 (26%), Positives = 318/779 (40%), Gaps = 95/779 (12%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHC--GAAYEDFNIQLRRSQE--SAAPTLSRV 136
            C  +G  HY TFDG +F F G C Y+ +  C   ++   F+++ +      SA   +  +
Sbjct: 322  CVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKEL 381

Query: 137  LMKVDGVVIQLTKGSV-------LVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMW 189
             ++V+G  I + KGS        LV   PV L      V I QS   T VE   GL++ +
Sbjct: 382  SVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGT--VKIYQSGISTAVETDFGLLVTF 439

Query: 190  NHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTK-LTPMEFGNLQKMDDPTEQC 248
            +      + +   Y N TCGLCG++N  P+   L       ++ ++ G   ++     +C
Sbjct: 440  DGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKC 499

Query: 249  QDPVPEPPRNCSTGFGICEELLHGQLFSG-----------CVALVDVGSYLEACRQDLCF 297
                 +   NC+      E L  G  + G           C  +VD  +++ +C  DLC 
Sbjct: 500  DSGCVD---NCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCS 556

Query: 298  CEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQ--KCPNNMQYHECRSPCADTC 355
              D   L  +C  +  Y+  C   G    DWR    C    +CP+   Y  C S C DTC
Sbjct: 557  VRDNGTL--LCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTC 614

Query: 356  SNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDC 413
            S+   SR C   C  GC C +G VL     + CVP+ KC C ++G  Y  G  +  + +C
Sbjct: 615  SDLTASRNCATPCTEGCECNQGFVL---STSQCVPLHKCGCDFDGHYYTMGEFFWATANC 671

Query: 414  T-NCTC-SGGRWSCQEVPCPG--TCSVLGGAH-----------------FSTFDGKQYTV 452
            T  C C  GG   C    C     C+V  G                     TFDG  Y  
Sbjct: 672  TVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAF 731

Query: 453  HGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLN 512
              + SY L K C      +  ++ +         L+ + + +   +  +    + EV LN
Sbjct: 732  PSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLN 791

Query: 513  QIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQ------LFMQLAPKLRGQ 566
                +LP        F PS    I +      +  + V T+Q      L+++L+      
Sbjct: 792  GQEVELP-------FFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNC 844

Query: 567  TCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT-QAACPNIRNSFEDPCSLSVENEK 625
            T GLCG +N+  +D+F   +G      A F  ++ T +  C          C+   E  K
Sbjct: 845  TGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLK 904

Query: 626  Y--AQHWCSQLTD-ADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHAC 682
            +  ++  C  + D ++  F  CH  V    YY  C+F  C    +E  LC +++ Y  AC
Sbjct: 905  FYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASAC 964

Query: 683  AAKGVQLGGWRD-GVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDI---TCSVGFIPV 738
                V++G WR    C      CP++  +   + TC  TC +L+ G I   +CS      
Sbjct: 965  KNADVEVGPWRTYDFCP---LECPENSHFEECI-TCTETCETLTLGPICVDSCS------ 1014

Query: 739  DGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVH---DSGAICTC--THGKLSC 792
            +GC C +G  L  + +CV  S C C   G  +   E+     D    C C  T  ++ C
Sbjct: 1015 EGCQCDEGYALLGS-QCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHC 1072



 Score =  198 bits (503), Expect = 5e-50
 Identities = 236/978 (24%), Positives = 359/978 (36%), Gaps = 177/978 (18%)

Query: 371  GCFCPEGTVL-DDIGQTGCVPVSKCACV-YNGAAYAPGATYSTDCTNCTCSGGRWSCQEV 428
            G F   G V  DD+  T      KC C+ +N   Y   A+ S     C   G  + C  V
Sbjct: 264  GQFLRRGEVFWDDLNCT-----VKCRCLDFNNEIYCQEASCSP-YEVCEPKGKFFYCSAV 317

Query: 429  PCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSA----FTVLA--ELRRCGLTD 482
                TC V G  H+ TFDG  +   G C+Y+L + C  ++    F+V A  E RR     
Sbjct: 318  ET-STCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRR---GS 373

Query: 483  SETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISA--ANVTIFRPSTFFIIAQTS 540
            + + +K +++ ++G + ++   + G V +N + T LP++     V I++ S      +T 
Sbjct: 374  AVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQ-SGISTAVETD 432

Query: 541  LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600
             GL +           + +       TCGLCGN+N    DDF    G    +      ++
Sbjct: 433  FGLLVTFD--GQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESW 490

Query: 601  KTQAACPNIRNSFEDPCS---LSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNC 657
            +   A     +   D C+    + E   +   +C  L   DGP   C   V P  +  +C
Sbjct: 491  RVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSC 550

Query: 658  MFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTC 717
            ++D C+   +   LC A+ +Y   C A G+ +G WR          CP    Y    S+C
Sbjct: 551  VYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSC 610

Query: 718  QPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVH 777
              TC  L+     C+      +GC C +G F+  T +CV    C C   G     GE   
Sbjct: 611  PDTCSDLT-ASRNCATPC--TEGCECNQG-FVLSTSQCVPLHKCGCDFDGHYYTMGEFF- 665

Query: 778  DSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSP 837
               A   CT   L   GG                                   D+ C++ 
Sbjct: 666  --WATANCTVQCLCEEGG-----------------------------------DVYCFNK 688

Query: 838  QCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDD 897
             C  G VC    V DG  GC    +  C+ ++      Q +                   
Sbjct: 689  TCGSGEVC---AVEDGYQGCFPKRETVCLLSQ-----NQVLH------------------ 722

Query: 898  PCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTG 957
                           TFDG SY+F  +  YTL++  C      +  +  +  N      G
Sbjct: 723  ---------------TFDGASYAFPSEFSYTLLKT-C----PERPEYLEIDINKKKPDAG 762

Query: 958  TTCSKAIKIFLGGFELKLSH-GKVEVIGTDESQEVPY----------------TIRQMGI 1000
                + ++I +   E+K+   G  EV    +  E+P+                T+   G+
Sbjct: 763  PAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGV 822

Query: 1001 YLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLE 1060
              V  +DIGL         ++I LS  +     GLCG ++  A ++F   +     ++  
Sbjct: 823  VTVQYSDIGL---------LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAV 873

Query: 1061 FGNSWK-----LSPSCPDAL-APKDPCTANPFRKSWAQKQCSILHGP---TFAACHAHVE 1111
            F  SW       +  C D L A  +      F +S  + +C I++ P   +F  CH  V 
Sbjct: 874  FLESWTTFEEICNGECGDLLKACNNDSELLKFYRS--RSRCGIINDPSNSSFLECHGVVN 931

Query: 1112 PARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTPSICPLFCDYYNP 1170
               YY  C+     C SGG+    C +VA YA AC    + V  WRT   CPL C    P
Sbjct: 932  VTAYYRTCL--FRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLEC----P 985

Query: 1171 EGQCEWHYQPCGVPCLRTCRN-PRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCP 1229
            E     H++ C + C  TC     G    D    EGC  +C     +      QCV    
Sbjct: 986  ENS---HFEEC-ITCTETCETLTLGPICVDSCS-EGC--QCDEGYALLGS---QCVTRSE 1035

Query: 1230 TPPLPPRCHVHGKSYRPGAVVPSDKNCQ-SCLCTERGVECTYKAEACVCTYNGQRFHPGD 1288
                   C+  G           D +CQ  C C+  G +     E   C  +      G 
Sbjct: 1036 C-----GCNFEGHQLATNETFWVDLDCQIFCYCS--GTDNRVHCETIPCKDDEYCMEEGG 1088

Query: 1289 VIYHTTDGTGGCISARCG 1306
            + Y        CI +  G
Sbjct: 1089 LYYCQARTDASCIVSGYG 1106



 Score =  173 bits (438), Expect = 2e-42
 Identities = 165/671 (24%), Positives = 257/671 (38%), Gaps = 78/671 (11%)

Query: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVF----SEHCGAAYEDFNIQLRRSQESAAPTLSRV 136
            C   G  HY TFDG  F F   C  +     S     ++  F +  +   E   P+L+  
Sbjct: 1100 CIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKN--EDRDPSLALW 1157

Query: 137  LMKVDGVVIQLT-------KGSVLVNGHPVLLPFS--QSGVLIQQSSSYTKVEARLGLVL 187
            + +VD  V   +       K +VLVN   + LP    Q  + I     +  VE   GL +
Sbjct: 1158 VKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKV 1217

Query: 188  MWNHDDSLLLELDTKYANKTCGLCGDFNGMP-----VVSELLSHNTKLTPMEFGNLQKMD 242
            +++    L + +     N T GLCG +NG P     +   LL+ +      EFG      
Sbjct: 1218 VYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVN----EFGQSWVKR 1273

Query: 243  DPTEQ--CQDPVPEPPRNCSTGFGICEELL-----HGQLFSGCVALVDVGSYLEACRQDL 295
            D   Q  C D  P   +    GF   ++L          FS C + V+   + + C  D 
Sbjct: 1274 DTFCQVGCGDRCPSCAK--VEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDS 1331

Query: 296  CFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTC 355
            C   D   +   C  L  Y+  C   G     WR    C   CP N  Y  C S C   C
Sbjct: 1332 CI--DGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRC 1389

Query: 356  SNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY-STDCT 414
            +       C  +CV GC C  G VL+      C+    C C  +G  Y P   + ++DCT
Sbjct: 1390 AAIRLKSDCSHYCVEGCHCDAGYVLNG---KSCILPHSCGCYSDGKYYEPKQLFWNSDCT 1446

Query: 415  N-CTCSGGRW-SCQEVPCPGT-------------------CSVLGGAHFSTFDGKQYTVH 453
              C C       C    C                      C   GG  F TFDG      
Sbjct: 1447 RRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFP 1506

Query: 454  GDCSYVLTKPCDSS---AFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVF 510
             +C++VL+  C      +F ++    +    +  T +  V   ++  Q  ++I     V 
Sbjct: 1507 ANCAFVLSTICQKLPDISFQLIINFDKWSAPNL-TIISPVYFYINEEQ--ILINDRNTVK 1563

Query: 511  LNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGL 570
            +N     +P      T    S  F++  TS  +Q+       +++   ++ +L+ + CGL
Sbjct: 1564 VNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKI--SISERLQNKVCGL 1621

Query: 571  CGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQA--------ACPNIR-NSFEDPCSLSV 621
            CGNFN    DD+ TL G    ++     ++KT          +C  ++ + +   C    
Sbjct: 1622 CGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVH 1681

Query: 622  ENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHA 681
              +     +C +LTD  G F  C+  + P  +Y +C  D C   +    LC +L++Y  A
Sbjct: 1682 IQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQ-LCGSLAAYGEA 1740

Query: 682  CAAKGVQLGGW 692
            C + G+    W
Sbjct: 1741 CRSFGILSTEW 1751



 Score =  140 bits (354), Expect = 1e-32
 Identities = 135/538 (25%), Positives = 204/538 (37%), Gaps = 79/538 (14%)

Query: 823  CQKSCHTLDM--TCYSPQCVPGCVCPDGLVADGEGGCITAEDCPC-------VHNEA--- 870
            C ++C TL +   C    C  GC C +G    G   C+T  +C C         NE    
Sbjct: 996  CTETCETLTLGPICVD-SCSEGCQCDEGYALLGSQ-CVTRSECGCNFEGHQLATNETFWV 1053

Query: 871  -------SYRAGQTIRVGCNTCTCDSRMWRCTDDPCL--------ATCAVYGDGHYLTFD 915
                    Y +G   RV C T  C    + C ++  L        A+C V G GHYLTFD
Sbjct: 1054 DLDCQIFCYCSGTDNRVHCETIPCKDDEY-CMEEGGLYYCQARTDASCIVSGYGHYLTFD 1112

Query: 916  GQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKL 975
            G  + F   C   L          +   F V  +N     +     K + + + G+ + +
Sbjct: 1113 GFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVI 1172

Query: 976  SHG-KVEVIGTDESQEVPYTIRQ-------MGIYLVVDTDIGLVLLWDKKTSIFINLSPE 1027
                K  V+   E   +P  + Q        G ++VV+TD GL +++D KT + I +   
Sbjct: 1173 HRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRS 1232

Query: 1028 FKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSW-KLSPSCPDALAPKDPCTANPF 1086
             +    GLCG ++    +D       +   V EFG SW K    C      + P  A   
Sbjct: 1233 MQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGDRCPSCAKVE 1292

Query: 1087 RKSWAQKQCSIL--HGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQ 1144
              S  Q+ CS++      F+ CH+ V P  +Y+ C+ D+C    GG  +  C+ +  YA 
Sbjct: 1293 GFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCI--DGGAVQTACSWLQNYAS 1350

Query: 1145 ACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPR--GDCLRDVW 1201
             C   G+ V+ WR  + C + C   +       HY+ C   C   C   R   DC    +
Sbjct: 1351 TCQTQGITVTGWRNYTSCTVTCPPNS-------HYESCVSVCQPRCAAIRLKSDCSH--Y 1401

Query: 1202 GLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLC 1261
             +EGC+  C     +   +   C+      P    C+  GK Y P  +  +    + C C
Sbjct: 1402 CVEGCH--CDAGYVL---NGKSCIL-----PHSCGCYSDGKYYEPKQLFWNSDCTRRCRC 1451

Query: 1262 TERGV------------ECTYK--AEACVCTYNGQRFHPGDVIYHTTDGTGGCISARC 1305
              R V            EC  +     C  T        G  ++ T DG      A C
Sbjct: 1452 FRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANC 1509



 Score = 95.1 bits (235), Expect = 6e-19
 Identities = 97/387 (25%), Positives = 150/387 (38%), Gaps = 62/387 (16%)

Query: 823  CQKSCHTLDMTC-YSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQ----- 876
            CQ  C  + +    S  CV GC C  G V +G+  CI    C C  +   Y   Q     
Sbjct: 1385 CQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKS-CILPHSCGCYSDGKYYEPKQLFWNS 1443

Query: 877  --TIRVGC---NTCTCDSRMWRCTDD--------PCLAT----CAVYGDGHYLTFDGQSY 919
              T R  C   N   CD R  +  ++         C +T    C   G G + TFDG   
Sbjct: 1444 DCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFL 1503

Query: 920  SFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLS-HG 978
             F  +C + L    C  +     SF+++           T    +  ++   ++ ++   
Sbjct: 1504 RFPANCAFVL-STIC--QKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRN 1560

Query: 979  KVEVIGTDESQEVPYT------IRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRV 1032
             V+V GT  +  VP+       I     +LV+DT   + + ++    I I++S   + +V
Sbjct: 1561 TVKVNGTQVN--VPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKV 1618

Query: 1033 CGLCGNFDDIAVNDFAT-RSRSVVGDVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWA 1091
            CGLCGNF+    +D+ T R + VV  V+    SWK +      LAP    + N  + S  
Sbjct: 1619 CGLCGNFNGDLTDDYVTLRGKPVVSSVV-LAQSWKTNGMQKRPLAP----SCNELQFSQY 1673

Query: 1092 QKQCSILH----------------GPTFAACHAHVEPARYYEACVNDACACDSGGDCECF 1135
               C  +H                   F  C+  ++P  +YE+C  D C           
Sbjct: 1674 AAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQ---L 1730

Query: 1136 CTAVAAYAQACHEVG-LCVSWRTPSIC 1161
            C ++AAY +AC   G L   W     C
Sbjct: 1731 CGSLAAYGEACRSFGILSTEWIEKENC 1757


>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
          Length = 1503

 Score =  189 bits (480), Expect = 2e-47
 Identities = 168/613 (27%), Positives = 238/613 (38%), Gaps = 120/613 (19%)

Query: 716  TCQPTCRS-LSEGDITCSVG-FIPVDG----CICPKGTFLDDTGKCVQASN--------- 760
            +C P CR  L+ G+       ++P D     C+C +G       +C+ +           
Sbjct: 888  SCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDC 947

Query: 761  CP----CYHRGSMIPNGESVH---DSGAICTCTHG-----KLSCIGGQAPAPVCAAPMVF 808
            CP    C H G     GES     D   +C C         L C   Q P+ V   P   
Sbjct: 948  CPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQL 1007

Query: 809  FD---------CRNA-------------TPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCP 846
                       C  A              P D    CQ  C  L   C    C P   CP
Sbjct: 1008 LPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQ--CQDLTWLCIHQAC-PELSCP 1064

Query: 847  DGLVADGEGGCITAEDCP---CVHNEASYRAGQTIRVG-CNTCTCDSRMWRCTDDPCL-- 900
                    G C      P   CVH      +G+   V  C +C+C +   RC    C   
Sbjct: 1065 LSERHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPL 1124

Query: 901  -----------------------ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGK 937
                                   A+C  +GD HY TFDG+   F G C Y L       K
Sbjct: 1125 SCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLA------K 1178

Query: 938  DSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKL-SHGKVEVIGTDES----QEVP 992
            D     F V   N   G +G   ++ + + LG   ++L   G V V G   +    QE  
Sbjct: 1179 DCHSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPL 1238

Query: 993  YTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSR 1052
              +   G  +++    GL +LWD ++ + +++   ++GR CGLCGNF+  A +D      
Sbjct: 1239 LYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEG 1298

Query: 1053 SVVGDVLEFGNSWKLS----PSCP-DALAPKDPCTANPFR-KSWAQKQCSILHGPTFAAC 1106
             ++     FGNSW++S    P  P  A    DPC A  +R +  A  +C +L    F+ C
Sbjct: 1299 LLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRC 1358

Query: 1107 HAHVEPARYYEACVNDACACDSGGDCE-CFCTAVAAYAQACHEVGLCVSWRTPSICPLFC 1165
            HA V P  ++ ACV D CAC  G   + C C A+ AYA  C + G+  +WR P++C + C
Sbjct: 1359 HAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGC 1418

Query: 1166 DYYNPEGQCEWHYQPCGVPCLRTCRN---PRGD----CLRDVWGLEGCYPKCPPEAPIFD 1218
                   +  + +  CG PC RTC N   P G+    C+R       C P C   A +  
Sbjct: 1419 PL-----ERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRP------CVPGCQCPAGLV- 1466

Query: 1219 EDKMQCV--ATCP 1229
            E +  C+    CP
Sbjct: 1467 EHEAHCIPPEACP 1479



 Score =  158 bits (399), Expect = 6e-38
 Identities = 120/376 (31%), Positives = 169/376 (44%), Gaps = 43/376 (11%)

Query: 43   SPIARGPSGVP-LRGATVFPSLRTIPVVRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPG 101
            SP++ GP   P L   +  P  R +P      PA     C  +G  HY+TFDG +  F G
Sbjct: 1122 SPLSCGPDKAPALSPGSCCP--RCLP-----RPAS----CMAFGDPHYRTFDGRLLHFQG 1170

Query: 102  LCNYVFSEHCGAAYEDFNIQLR---RSQESAAPTLSRVLMKVDGVVIQLTKGSVLVNGHP 158
             C+YV ++ C +   DF++ +    R +   A T    ++  D  V  L  G+V V+GHP
Sbjct: 1171 SCSYVLAKDCHSG--DFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHP 1228

Query: 159  VLLPFSQSGVLIQQSSSYTKV-EARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGM 217
            V LPF Q  +L  +   +T +  A+ GL ++W+    + + +   Y  +TCGLCG+FNG 
Sbjct: 1229 VALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGF 1288

Query: 218  PVVSELLSHNTKLTPME--FGNLQKMDD---PTEQCQDPVPEPPRNCSTGFGICEE---- 268
                +L      L P E  FGN  ++ +   P   C       P   + G+    E    
Sbjct: 1289 -AQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCR-AAGYRARREANAR 1346

Query: 269  --LLHGQLFSGCVALVDVGSYLEACRQDLCFC-EDTDLLSCVCHTLAEYSRQCTHAGGLP 325
              +L    FS C A+V    +  AC  DLC C   +   +C+C  L  Y+  C  AG  P
Sbjct: 1347 CGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTP 1406

Query: 326  QDWRGPDFCPQKCP--NNMQYHECRSPCADTCSNQ-----EHSRACEDHCVAGCFCPEGT 378
              WRGP  C   CP      + EC  PC  TC NQ     E +  C   CV GC CP G 
Sbjct: 1407 -TWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGL 1465

Query: 379  VLDDIGQTGCVPVSKC 394
            V     +  C+P   C
Sbjct: 1466 VEH---EAHCIPPEAC 1478



 Score =  141 bits (356), Expect = 6e-33
 Identities = 134/521 (25%), Positives = 191/521 (36%), Gaps = 82/521 (15%)

Query: 306  CVCHTLAE-------YSRQCTHAGGLPQDWR---GPDFCPQKCPNNMQYHECRS------ 349
            C+C    E       + RQC    G P       GP  C   C   +    C        
Sbjct: 977  CICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALS--NCSEGLLGSE 1034

Query: 350  -----PCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKC---ACVYNGA 401
                 PC  TC  Q+ +  C         CP        G   C PV +    +CV+ G 
Sbjct: 1035 LAPPDPCY-TCQCQDLTWLCIHQACPELSCPLSERHTPPGS--CCPVCRAPTQSCVHQGR 1091

Query: 402  AYAPGATYSTD-CTNCTCSGGRWSCQEVPC-------------------------PGTCS 435
              A G  ++ D CT+C+C  G   CQ   C                         P +C 
Sbjct: 1092 EVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCM 1151

Query: 436  VLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLD 495
              G  H+ TFDG+     G CSYVL K C S  F+V       G +      +   L  D
Sbjct: 1152 AFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSGVAWTQEVAVLLGD 1211

Query: 496  GVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQL 555
                 V +   G V ++     LP     +         +I     GLQ+        Q+
Sbjct: 1212 ---MAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWD--GQSQV 1266

Query: 556  FMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAAC----PNIRN 611
             + +    +G+TCGLCGNFN    DD +   G++  + AAF N+++         P    
Sbjct: 1267 EVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAG 1326

Query: 612  SFEDPC-SLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNC---ERS 667
               DPC +      + A   C  L  +  PF RCHA V P  +++ C++D C C     +
Sbjct: 1327 REVDPCRAAGYRARREANARCGVLKSS--PFSRCHAVVPPEPFFAACVYDLCACGPGSSA 1384

Query: 668  EDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTC------ 721
            + CLC AL +Y   C   GV    WR    T  +  CP    + +    C P C      
Sbjct: 1385 DACLCDALEAYASHCRQAGV-TPTWRGP--TLCVVGCPLERGFVF--DECGPPCPRTCFN 1439

Query: 722  RSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCP 762
            + +  G++        V GC CP G  ++    C+    CP
Sbjct: 1440 QHIPLGELAAHCVRPCVPGCQCPAG-LVEHEAHCIPPEACP 1479



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 60/220 (27%), Positives = 79/220 (35%), Gaps = 49/220 (22%)

Query: 1065 WKLSPSCPD-ALAPKDPCTANPFRKSWAQKQCSI-LHGPTFAACHAHVEPARYYEACVND 1122
            W L  + P+ A    D CTA   +   A   C    H P    C  + +     E    D
Sbjct: 97   WGLGRAWPEGARWEPDACTACVCQDGAAH--CGPQAHLPHCRGCSQNGQTYGNGETFSPD 154

Query: 1123 ACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPS-ICPLFCDYYNPEGQCEWHY--- 1178
            AC       C C   AV     +C E+    S   P   CP+ C     EG   W +   
Sbjct: 155  ACTT-----CRCLTGAVQCQGPSCSELNCLESCTPPGECCPICCT----EGGSHWEHGQE 205

Query: 1179 -QPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTP--PLPP 1235
                G PC R CR     CL      EG + +C          + +C + CP P  PLP 
Sbjct: 206  WTTPGDPC-RICR-----CL------EG-HIQCR---------QRECASLCPYPARPLPG 243

Query: 1236 RC-------HVHGKSYRPGAVVPSDKNCQSCLCTERGVEC 1268
             C        ++G+ +R G  V S   C  C C    V+C
Sbjct: 244  TCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQC 283



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 108/500 (21%), Positives = 143/500 (28%), Gaps = 115/500 (23%)

Query: 388 CVPVSKCACVYNGAAYAPGATYSTD--CTNCTCSGGRWSCQEVPCPGT-CSVLG---GAH 441
           C PV    C  NG  +  G    +   C++C C+ G   C+ +PCP   C   G   G  
Sbjct: 245 CCPVCD-GCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQC 303

Query: 442 FSTFDGKQYTVHGDCSYV--------LTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLS 493
               DG +Y  H   S          L   C   A  V  E + C +T          L 
Sbjct: 304 CPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVT-------PCALP 356

Query: 494 LDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTM 553
             G Q     +  GE F   +                                       
Sbjct: 357 ASGRQLCPACELDGEEFAEGV--------------------------------------- 377

Query: 554 QLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSF 613
               Q  P   G+ C  C     +  D       V+   A     T    A CP+     
Sbjct: 378 ----QWEPD--GRPCTAC-----VCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC---- 422

Query: 614 EDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCA 673
            D C  +  ++ YA       TDAD P   CH   + GT        TC+        CA
Sbjct: 423 -DSC--TYHSQVYANG--QNFTDADSPCHACHC--QDGTV-------TCSLVDCPPTTCA 468

Query: 674 ALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSV 733
              S    C          R   C           ++ +    CQ  CR   EG   C  
Sbjct: 469 RPQSGPGQCCP--------RCPDCILEEEVFVDGESFSHPRDPCQ-ECR-CQEGHAHCQP 518

Query: 734 GFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESV---HDSGAICTCTHGKL 790
              P   C  P        G C       C   G   P+G       D   +C C  G +
Sbjct: 519 RPCPRAPCAHPL------PGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNV 572

Query: 791 SCIGGQAPAPVCAAPMVF-FDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGL 849
            C+  +     C  P++   +C    P   G     + H      +SP   PG  C   L
Sbjct: 573 QCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSP---PGDPCRRCL 629

Query: 850 VADGEGGC--ITAEDCPCVH 867
             DG   C  +     PC H
Sbjct: 630 CLDGSVSCQRLPCPPAPCAH 649



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 57/236 (24%), Positives = 72/236 (30%), Gaps = 66/236 (27%)

Query: 244 PTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCED--- 300
           P   CQ P  +PP  C      C    H Q+++      D  S   AC      C+D   
Sbjct: 404 PPAPCQHPT-QPPGACCPSCDSCT--YHSQVYANGQNFTDADSPCHACH-----CQDGTV 455

Query: 301 -TDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHEC----------RS 349
              L+ C   T A            PQ   GP  C  +CP+ +   E           R 
Sbjct: 456 TCSLVDCPPTTCAR-----------PQS--GPGQCCPRCPDCILEEEVFVDGESFSHPRD 502

Query: 350 PCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
           PC + C  QE    C+        CP       +  T C P     C + G  Y  GA +
Sbjct: 503 PCQE-CRCQEGHAHCQPRP-----CPRAPCAHPLPGT-CCPNDCSGCAFGGKEYPSGADF 555

Query: 410 ---STDCTNCTCSGGRWSC---------------------QEVPCPGTCSVLGGAH 441
              S  C  C C  G   C                      + P P  C   G AH
Sbjct: 556 PHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAH 611



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 36/113 (31%), Positives = 47/113 (41%), Gaps = 22/113 (19%)

Query: 359 EHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTD-CTNCT 417
           E +R   D C A C C +G      G    +P  +  C  NG  Y  G T+S D CT C 
Sbjct: 105 EGARWEPDACTA-CVCQDGAA--HCGPQAHLPHCR-GCSQNGQTYGNGETFSPDACTTCR 160

Query: 418 CSGGRWSCQEVPC-----------PGTCSVL----GGAHFSTFDGKQYTVHGD 455
           C  G   CQ   C           PG C  +    GG+H+    G+++T  GD
Sbjct: 161 CLTGAVQCQGPSCSELNCLESCTPPGECCPICCTEGGSHWE--HGQEWTTPGD 211



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 61/245 (24%), Positives = 80/245 (32%), Gaps = 51/245 (20%)

Query: 700 PMTTCPK--SMTYHYHV-------STCQPTCRSL--SEGDITCSVGFIPVDGCICPKGTF 748
           P   CP   S TYH  V       +     C +    +G +TCS+   P   C  P+   
Sbjct: 415 PGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQS-- 472

Query: 749 LDDTGKCVQASNCP-CYHRGSMIPNGESV---HDSGAICTCTHGKLSCIGGQAPAPVCAA 804
               G+C     CP C     +  +GES     D    C C  G   C     P   CA 
Sbjct: 473 --GPGQC--CPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAH 528

Query: 805 PMVFFDCRNATPGDTGAGCQ--------------KSCHTL--DMTCYSPQCVPGCVCPDG 848
           P+    C N   G    G +              + C  L  ++ C + +CVP   CP+ 
Sbjct: 529 PLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVP-LPCPEP 587

Query: 849 LVADGE--------GGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPC- 899
           ++  GE         GC         H E     G      C  C C      C   PC 
Sbjct: 588 VLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDP----CRRCLCLDGSVSCQRLPCP 643

Query: 900 LATCA 904
            A CA
Sbjct: 644 PAPCA 648



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 72/320 (22%), Positives = 101/320 (31%), Gaps = 82/320 (25%)

Query: 1166 DYYNPEGQCEWHYQPCG-VPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQC 1224
            ++  P G CEW     G V C+R  + P   C   V     C P+C              
Sbjct: 849  EFEGPAGSCEWCRCQAGQVSCVRL-QCPPLPCKLQVTERGSCCPRCRG------------ 895

Query: 1225 VATCPTPPLPPRCHVHGKSYRPGAV-VPSDKNCQSCLCTERGVECT--YKAEACV----- 1276
                        C  HG+ +  G+  VP D  C SC+C E  V C       +C      
Sbjct: 896  ------------CLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQG 943

Query: 1277 ----------CTYNGQRFHPGDVIYHTTDGTGGCI---------SARCGANGTIERRVYP 1317
                      C + G+++ PG+      D    CI         S RC       RR  P
Sbjct: 944  PHDCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRC------HRRQCP 997

Query: 1318 ----CSPTTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSS---------AWPTTA 1364
                C P+  +PP        P    +    S G   +   PP            W    
Sbjct: 998  SLVGCPPSQLLPPGPQHCC--PTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIH 1055

Query: 1365 GTSPRTRLPTASASLPP-VCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRA----HGYR 1419
               P    P +    PP  C   C  +P       GR   SG+  T++   +     G  
Sbjct: 1056 QACPELSCPLSERHTPPGSCCPVCR-APTQSCVHQGREVASGERWTVDTCTSCSCMAGTV 1114

Query: 1420 VCESPR--SVECRAEDAPGV 1437
             C+S R   + C  + AP +
Sbjct: 1115 RCQSQRCSPLSCGPDKAPAL 1134



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 67/281 (23%), Positives = 93/281 (33%), Gaps = 71/281 (25%)

Query: 667 SEDC-LCAALSSYVHACAAKGVQLGGWRDGVCTKPMTT-------------CPKSMTYH- 711
           S+ C LC  LS  V   A + V L       C +P+               CP+    H 
Sbjct: 559 SDPCRLCRCLSGNVQCLARRCVPLP------CPEPVLLPGECCPQCPAPAGCPRPGAAHA 612

Query: 712 ----YHVSTCQPTCRSLS-EGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHR 766
               Y      P  R L  +G ++C     P   C  P+       G C  + +  C ++
Sbjct: 613 RHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPR------QGPCCPSCD-GCLYQ 665

Query: 767 GSMIPNGESVHDSGA---ICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGC 823
           G    +GE      A   +C C  G +SC       P   AP +   C     GD    C
Sbjct: 666 GKEFASGERFPSPTAACHLCLCWEGSVSC------EPKACAPAL---CPFPARGDCCPDC 716

Query: 824 QKSCHTLDMTCYSPQCVPG-------CVCPDGLVADGEGGCI----------TAEDCP-- 864
              C  L  +  S Q  P        C C  G V  G   C           +   CP  
Sbjct: 717 D-GCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTC 775

Query: 865 --CVHNEASYRAGQTIR----VGCNTCTCDSRMWRCTDDPC 899
             C ++  +  +G+T+       C+ CTC     RC   PC
Sbjct: 776 QGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPC 816



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 48/204 (23%), Positives = 70/204 (34%), Gaps = 38/204 (18%)

Query: 727 GDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCP----CYHRGSMIPNGESVHD---- 778
           G +TC        GC  P    L  +G C     CP    C + G    +GE++ D    
Sbjct: 747 GFVTCGRRPCEPPGCSHP----LIPSGHC-----CPTCQGCRYHGVTTASGETLPDPLDP 797

Query: 779 SGAICTCTHGKLSCIGGQAPAPVCAAPM-------VFFDC----RNATPGDTGAGCQKSC 827
           + ++CTC  G + C     P  +C  P        V   C    R    G+   G   SC
Sbjct: 798 TCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSC 857

Query: 828 HTL-----DMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTI--RV 880
                    ++C   QC P    P  L     G C         H E      + +    
Sbjct: 858 EWCRCQAGQVSCVRLQCPP---LPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDS 914

Query: 881 GCNTCTCDSRMWRCTDDPCLATCA 904
            C++C C   +  C    C+++CA
Sbjct: 915 ACSSCVCHEGVVTCARIQCISSCA 938



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 47/179 (26%), Positives = 63/179 (35%), Gaps = 37/179 (20%)

Query: 318 CTHAGGLPQDWRGPDFCPQK-CPNNMQYHECRSPCADTCS-------NQEHSRACEDHCV 369
           C    G+P+   G   CP   C +  Q      P  D+C+       N ++    +  C 
Sbjct: 389 CVCQDGVPKC--GAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCH 446

Query: 370 AGCFCPEGTV---LDDIGQTGCV-----PVSKCA----CVYNGAAYAPGATYS---TDCT 414
           A C C +GTV   L D   T C      P   C     C+     +  G ++S     C 
Sbjct: 447 A-CHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQ 505

Query: 415 NCTCSGGRWSCQEVPC---------PGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPC 464
            C C  G   CQ  PC         PGTC          F GK+Y    D  +  + PC
Sbjct: 506 ECRCQEGHAHCQPRPCPRAPCAHPLPGTCCP-NDCSGCAFGGKEYPSGADFPHP-SDPC 562



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 61/259 (23%), Positives = 77/259 (29%), Gaps = 94/259 (36%)

Query: 1069 PSCPDALA-------------PKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARY 1115
            P CPD +              P+DPC           ++C    G      HAH +P   
Sbjct: 479  PRCPDCILEEEVFVDGESFSHPRDPC-----------QECRCQEG------HAHCQPRPC 521

Query: 1116 YEA----------CVNDACACDSGGD-----------------CECFCTAVAAYAQACHE 1148
              A          C ND   C  GG                  C C    V   A+ C  
Sbjct: 522  PRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVP 581

Query: 1149 VGL----------CVSWRTPSICPLFCDYYNP---EGQCEWHYQPCGVPCLRT-CRNPRG 1194
            +            C     P+ CP       P     + + ++ P G PC R  C +   
Sbjct: 582  LPCPEPVLLPGECCPQCPAPAGCP------RPGAAHARHQEYFSPPGDPCRRCLCLDGSV 635

Query: 1195 DCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDK 1254
             C R           CPP AP     +  C  +C        C   GK +  G   PS  
Sbjct: 636  SCQR---------LPCPP-APCAHPRQGPCCPSCDG------CLYQGKEFASGERFPSPT 679

Query: 1255 N-CQSCLCTERGVECTYKA 1272
              C  CLC E  V C  KA
Sbjct: 680  AACHLCLCWEGSVSCEPKA 698



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 53/204 (25%), Positives = 72/204 (35%), Gaps = 33/204 (16%)

Query: 243 DPTEQCQDPVPEPPRNCS-TGFGICEELLHGQLFSG--CVALVDVGSYLEACRQDLCFCE 299
           D +  CQ  +P PP  C+    G C     G L+ G    +     S   AC   LC C 
Sbjct: 632 DGSVSCQR-LPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACH--LCLCW 688

Query: 300 DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCA------- 352
           +  + SC     A         G    D  G ++  +   +N ++ + R PC        
Sbjct: 689 EGSV-SCEPKACAPALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTCLGG 747

Query: 353 -DTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY-- 409
             TC      R CE    +    P G          C P  +  C Y+G   A G T   
Sbjct: 748 FVTCGR----RPCEPPGCSHPLIPSGH---------CCPTCQ-GCRYHGVTTASGETLPD 793

Query: 410 --STDCTNCTCSGGRWSCQEVPCP 431
                C+ CTC  G   CQ+ PCP
Sbjct: 794 PLDPTCSLCTCQEGSMRCQKKPCP 817



 Score = 38.5 bits (88), Expect = 0.067
 Identities = 33/124 (26%), Positives = 50/124 (40%), Gaps = 32/124 (25%)

Query: 1221 KMQCVATCPTPP---LPPRCHVHGKSYRPGA--VVPSDKNCQSCLCTERGVECTYKAEAC 1275
            ++ C+ +C TPP    P  C   G  +  G     P D  C+ C C E  ++C  +  A 
Sbjct: 175  ELNCLESC-TPPGECCPICCTEGGSHWEHGQEWTTPGDP-CRICRCLEGHIQCRQRECAS 232

Query: 1276 VCTY------------------NGQRFHPGDVIYHTTDGTGG-CISARCGANGTIERRVY 1316
            +C Y                  NG+    G+ +     G+G  C   RC ANG+++    
Sbjct: 233  LCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV-----GSGDPCSHCRC-ANGSVQCEPL 286

Query: 1317 PCSP 1320
            PC P
Sbjct: 287  PCPP 290



 Score = 38.1 bits (87), Expect = 0.088
 Identities = 31/113 (27%), Positives = 41/113 (36%), Gaps = 11/113 (9%)

Query: 325 PQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIG 384
           P D  G  F  ++ P+   +     PC   C     +  C         CPE  +L    
Sbjct: 536 PNDCSGCAFGGKEYPSGADFPHPSDPCR-LCRCLSGNVQCLARRCVPLPCPEPVLLPG-- 592

Query: 385 QTGCVPV--SKCACVYNGAAYAPGATYSTD----CTNCTCSGGRWSCQEVPCP 431
              C P   +   C   GAA+A    Y +     C  C C  G  SCQ +PCP
Sbjct: 593 --ECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCP 643



 Score = 37.0 bits (84), Expect = 0.20
 Identities = 41/147 (27%), Positives = 48/147 (32%), Gaps = 37/147 (25%)

Query: 306 CVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHS---- 361
           C C   A  S QC      P   R P   P +C           P  D C  Q H     
Sbjct: 274 CRC---ANGSVQCEPLPCPPVPCRHPGKIPGQC----------CPVCDGCEYQGHQYQSQ 320

Query: 362 ---RACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCA-----------CVYNGAAYAPGA 407
              R  E      C C  G V  +  +  C PV+ CA           C  +G  +A G 
Sbjct: 321 ETFRLQERGLCVRCSCQAGEVSCE--EQEC-PVTPCALPASGRQLCPACELDGEEFAEGV 377

Query: 408 TYSTD---CTNCTCSGGRWSCQEVPCP 431
            +  D   CT C C  G   C  V CP
Sbjct: 378 QWEPDGRPCTACVCQDGVPKCGAVLCP 404



 Score = 35.8 bits (81), Expect = 0.44
 Identities = 105/483 (21%), Positives = 133/483 (27%), Gaps = 100/483 (20%)

Query: 1145 ACHEVGLCVSWR----------TPSICPL-----------FCDYYNPEGQCEWHYQPCGV 1183
            ACH   LC+ W            P++CP             C+Y          +     
Sbjct: 681  ACH---LCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPRE 737

Query: 1184 PC-LRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGK 1242
            PC L TC      C R      GC     P           C  TC        C  HG 
Sbjct: 738  PCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSG--------HCCPTCQG------CRYHGV 783

Query: 1243 SYRPGAVVPS--DKNCQSCLCTERGVECTYK----------------AEAC-VCTYNGQR 1283
            +   G  +P   D  C  C C E  + C  K                   C  C   G+ 
Sbjct: 784  TTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGRE 843

Query: 1284 FHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPLVVSSTHT 1343
               G+         G C   RC A G +      C P       T   S  P        
Sbjct: 844  HQDGE---EFEGPAGSCEWCRCQA-GQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAH 899

Query: 1344 PSNGPSSAHTGPPSSAWPTTA---GTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGR 1400
                P  +   PP SA  +     G     R+   S+   P  G         D    GR
Sbjct: 900  GEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGR 959

Query: 1401 GTDSGDFDTLENLRAHGYRVC------ESPRSVECRAEDAPGV----PLRALGQRVQ-CS 1449
              + G+        A    VC      E P S+ C     P +    P + L    Q C 
Sbjct: 960  KYEPGE---SFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCC 1016

Query: 1450 PDVGLTCRNREQA--------SGLCYNYQIR-------VQCCTPLACSTS---SSPAQTT 1491
            P       N  +            CY  Q +        Q C  L+C  S   + P    
Sbjct: 1017 PTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCC 1076

Query: 1492 PPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTPS--PPPVPATS 1549
            P   + T      G    S    TV   T+ +  A GT     +  S  S  P   PA S
Sbjct: 1077 PVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMA-GTVRCQSQRCSPLSCGPDKAPALS 1135

Query: 1550 TSS 1552
              S
Sbjct: 1136 PGS 1138



 Score = 33.5 bits (75), Expect = 2.2
 Identities = 30/127 (23%), Positives = 46/127 (36%), Gaps = 28/127 (22%)

Query: 331 PDFCPQKCPNNMQYHECRSPCADTCSNQ--EHSRACEDHCVAG----CFCPEGTV----- 379
           P  CP   P       C  P   +C +Q  EH    E    AG    C C  G V     
Sbjct: 818 PALCPHPSPG-----PCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRL 872

Query: 380 --------LDDIGQTGCVPVSKCACVYNGAAYAPGATY---STDCTNCTCSGGRWSCQEV 428
                   L    +  C P  +  C+ +G  +  G+ +    + C++C C  G  +C  +
Sbjct: 873 QCPPLPCKLQVTERGSCCPRCR-GCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARI 931

Query: 429 PCPGTCS 435
            C  +C+
Sbjct: 932 QCISSCA 938



 Score = 32.0 bits (71), Expect = 6.3
 Identities = 40/154 (25%), Positives = 52/154 (33%), Gaps = 25/154 (16%)

Query: 303 LLSCVCHTLAEYSRQCTHAG-GLPQDWRG-PDFCPQ--------KCPNNMQYHECR--SP 350
           L SC CH     S QC   G   P+  R  PD C           C        CR  S 
Sbjct: 84  LESCECHPA---SPQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQAHLPHCRGCSQ 140

Query: 351 CADTCSNQE--HSRACED-HCVAGCFCPEGTVLDDIG-QTGCVPVSKCA---CVYNGAAY 403
              T  N E     AC    C+ G    +G    ++     C P  +C    C   G+ +
Sbjct: 141 NGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPICCTEGGSHW 200

Query: 404 APGATYSTD---CTNCTCSGGRWSCQEVPCPGTC 434
             G  ++T    C  C C  G   C++  C   C
Sbjct: 201 EHGQEWTTPGDPCRICRCLEGHIQCRQRECASLC 234


>gi|239757284 PREDICTED: similar to Fc fragment of IgG binding protein
            [Homo sapiens]
          Length = 593

 Score =  160 bits (405), Expect = 1e-38
 Identities = 156/590 (26%), Positives = 228/590 (38%), Gaps = 107/590 (18%)

Query: 535  IIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAA 594
            ++ +T  GL++   LV  +++   +      Q CGLCGN+N    DDF+  +G     A 
Sbjct: 21   VVIETDFGLRVAYDLVYYVRV--TVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNAN 78

Query: 595  AFFNTFKT---------QAACPNIRNSF--EDPCSLSVENEKYAQHWCSQLTDADGPFGR 643
             F N+++             CP           C   +E +   + +C  L+   GP   
Sbjct: 79   EFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 138

Query: 644  CHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWR-DGVCTKPMT 702
            CH  V P     +C+FD C    +   LC+ + +YV AC A G  +  WR +  C  PM 
Sbjct: 139  CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFC--PM- 195

Query: 703  TCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCP 762
             CP +  Y     TC   C +LS     C  G    +GC C  G FL +   CV    C 
Sbjct: 196  ECPPNSHYELCADTCSLGCSALS-APPQCQDGC--AEGCQCDSG-FLYNGQACVPIQQCG 251

Query: 763  CYHRGSMIPNGESV--HDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTG 820
            CYH G      ++V   +    CTC  GK+                              
Sbjct: 252  CYHNGVYYEPEQTVLIDNCRQQCTCHAGKV------------------------------ 281

Query: 821  AGCQKSCHTLDMTCYSPQCVPGCVC-PDGLVADGEGGCIT-------AEDCPCVHNEASY 872
                       + C    C PG VC P G    G   C+T       A+    V   A  
Sbjct: 282  -----------VVCQEHSCKPGQVCQPSG----GILSCVTKVTLRSLAQTGVDVEGAAIL 326

Query: 873  RAGQTIRV--------GCNTCTCDSRMWRCTDD----PCL----ATCAVYGDGHYLTFDG 916
              GQ ++V         C+  TC  +   C +      CL    ATC ++GD HY +FDG
Sbjct: 327  YNGQPLKVLLPLLSPDPCHGVTCRPQE-TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDG 385

Query: 917  QSYSFNGDCEYTLVQNHCGGKDSTQ--DSFRVVTENVPCGTTGTTCSKAIKIFLGGFELK 974
            + + F G C Y L    C G  STQ    F V T+N   G    +  + + +   G  + 
Sbjct: 386  RKFDFQGTCNYVLATTGCPGV-STQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNIS 444

Query: 975  LSH---GKVEVIGTDESQEVP-----YTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSP 1026
            +     GKV V G   +  V       ++ Q     ++  D GL + +D    + + L  
Sbjct: 445  IHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPS 504

Query: 1027 EFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL---SPSCPD 1073
             + G VCGLCGN D    ND    + ++   +  +G SW+     P C D
Sbjct: 505  SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWD 554



 Score =  125 bits (314), Expect = 4e-28
 Identities = 98/304 (32%), Positives = 128/304 (42%), Gaps = 29/304 (9%)

Query: 158 PVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGM 217
           PV+L   Q  +   Q  S   +E   GL + ++    + + +   Y  + CGLCG++NG 
Sbjct: 4   PVVLANGQ--IRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGD 61

Query: 218 PVVSELLSHNTKL-TPMEFGNLQKMDDPTEQCQDPVPEPP--RNCSTGFGICEEL----- 269
           P       + ++     EFGN  +   P   C  P P PP   +C        EL     
Sbjct: 62  PKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121

Query: 270 ---LHGQL------FSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQCTH 320
                G L       S C  LVD    L+ C  DLC       LS +C  +  Y   C  
Sbjct: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGN--LSILCSNIHAYVSACQA 179

Query: 321 AGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVL 380
           AGG  + WR   FCP +CP N  Y  C   C+  CS       C+D C  GC C  G + 
Sbjct: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLY 239

Query: 381 DDIGQTGCVPVSKCACVYNGAAYAPGATYSTD-C-TNCTCSGGR-WSCQEVPC-PG-TCS 435
           +  GQ  CVP+ +C C +NG  Y P  T   D C   CTC  G+   CQE  C PG  C 
Sbjct: 240 N--GQ-ACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQ 296

Query: 436 VLGG 439
             GG
Sbjct: 297 PSGG 300



 Score =  102 bits (255), Expect = 3e-21
 Identities = 78/280 (27%), Positives = 119/280 (42%), Gaps = 34/280 (12%)

Query: 997  QMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVG 1056
            Q G  +V++TD GL + +D    + + +   +  ++CGLCGN++    +DF   + S  G
Sbjct: 16   QHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAG 75

Query: 1057 DVLEFGNSWK--------LSPS-CP---DALAPKDPCTANPFRKSWAQKQCSILHGPT-- 1102
            +  EFGNSW+        L P+ CP   +   P   C     +K   ++ C +L  PT  
Sbjct: 76   NANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGP 135

Query: 1103 FAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTPSIC 1161
             ++CH  V+P    + C+ D C    GG+    C+ + AY  AC   G  V  WRT + C
Sbjct: 136  LSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFC 193

Query: 1162 PLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDK 1221
            P+ C    P    E     C + C      P+          +GC   C  ++  F  + 
Sbjct: 194  PMECP---PNSHYELCADTCSLGCSALSAPPQCQ--------DGCAEGCQCDSG-FLYNG 241

Query: 1222 MQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLC 1261
              CV     P     C+ +G  Y P   V  D   Q C C
Sbjct: 242  QACV-----PIQQCGCYHNGVYYEPEQTVLIDNCRQQCTC 276



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 46/160 (28%), Positives = 71/160 (44%), Gaps = 12/160 (7%)

Query: 81  CSTWGSFHYKTFDGDVFRFPGLCNYVF-SEHC-GAAYEDFN--IQLRRSQESAAPTLSR- 135
           C  WG  HY +FDG  F F G CNYV  +  C G + +         ++Q    P +S  
Sbjct: 372 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 431

Query: 136 --VLMKVDGVVIQLTK---GSVLVNGHPVLLPFS--QSGVLIQQSSSYTKVEARLGLVLM 188
             V +   G  I + K   G V VNG    LP S     + + Q +S   + A  GL + 
Sbjct: 432 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVS 491

Query: 189 WNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNT 228
           ++ +  + + L + Y    CGLCG+ +  P   ++  + T
Sbjct: 492 YDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT 531


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,019,625
Number of Sequences: 37866
Number of extensions: 5501533
Number of successful extensions: 103333
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 534
Number of HSP's successfully gapped in prelim test: 1142
Number of HSP's that attempted gapping in prelim test: 26950
Number of HSP's gapped (non-prelim): 29133
length of query: 2013
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1896
effective length of database: 13,817,196
effective search space: 26197403616
effective search space used: 26197403616
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.