Guide to the Human Genome
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Search of human proteins with 111160296

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3
[Homo sapiens]
         (875 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3 ...  1855   0.0  
gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1 ...   957   0.0  
gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens]          796   0.0  
gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens]         790   0.0  
gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens]          771   0.0  
gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5 (...   241   3e-63
gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4 (p...   238   2e-62
gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6 [...   190   4e-48
gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7 [...   187   5e-47
gi|239755573 PREDICTED: similar to ectonucleotide pyrophosphatas...    65   2e-10
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   52   2e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    52   2e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   44   5e-04
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   44   5e-04
gi|169217819 PREDICTED: similar to hCG1793095 [Homo sapiens]           44   7e-04
gi|239756564 PREDICTED: similar to hCG1793095 [Homo sapiens]           44   7e-04
gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]       42   0.002
gi|5174623 placental protein 11 precursor [Homo sapiens]               40   0.007
gi|224451073 endo/exonuclease (5'-3'), endonuclease G-like isofo...    39   0.016
gi|224451075 endo/exonuclease (5'-3'), endonuclease G-like isofo...    39   0.027
gi|169209673 PREDICTED: similar to hCG2042391 [Homo sapiens]           38   0.036
gi|169210658 PREDICTED: similar to hCG2042391 [Homo sapiens]           38   0.036
gi|169210188 PREDICTED: similar to hCG2042391 [Homo sapiens]           38   0.036
gi|239743493 PREDICTED: hypothetical protein XP_002342862 [Homo ...    37   0.061
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    37   0.080
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    37   0.080
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                    37   0.080
gi|10092665 sushi domain containing 2 [Homo sapiens]                   37   0.080
gi|187608446 phosphatidylinositol glycan anchor biosynthesis, cl...    35   0.23 
gi|187608438 phosphatidylinositol glycan anchor biosynthesis, cl...    35   0.23 

>gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3
           [Homo sapiens]
          Length = 875

 Score = 1855 bits (4804), Expect = 0.0
 Identities = 875/875 (100%), Positives = 875/875 (100%)

Query: 1   MESTLTLATEQPVKKNTLKKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFD 60
           MESTLTLATEQPVKKNTLKKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFD
Sbjct: 1   MESTLTLATEQPVKKNTLKKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFD 60

Query: 61  ASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCL 120
           ASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCL
Sbjct: 61  ASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCL 120

Query: 121 QRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTL 180
           QRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTL
Sbjct: 121 QRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTL 180

Query: 181 MPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLS 240
           MPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLS
Sbjct: 181 MPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLS 240

Query: 241 SKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERIS 300
           SKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERIS
Sbjct: 241 SKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERIS 300

Query: 301 TLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRN 360
           TLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRN
Sbjct: 301 TLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRN 360

Query: 361 LHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNS 420
           LHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNS
Sbjct: 361 LHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNS 420

Query: 421 EEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQWLAVRSKSNTNCGG 480
           EEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQWLAVRSKSNTNCGG
Sbjct: 421 EEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQWLAVRSKSNTNCGG 480

Query: 481 GNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLN 540
           GNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLN
Sbjct: 481 GNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLN 540

Query: 541 HLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPHLQNSTQLEQVNQMLNLTQEEI 600
           HLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPHLQNSTQLEQVNQMLNLTQEEI
Sbjct: 541 HLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPHLQNSTQLEQVNQMLNLTQEEI 600

Query: 601 TATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPT 660
           TATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPT
Sbjct: 601 TATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPT 660

Query: 661 VPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEE 720
           VPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEE
Sbjct: 661 VPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEE 720

Query: 721 FRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHY 780
           FRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHY
Sbjct: 721 FRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHY 780

Query: 781 FVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVR 840
           FVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVR
Sbjct: 781 FVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVR 840

Query: 841 DVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI 875
           DVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI
Sbjct: 841 DVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI 875


>gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1
           [Homo sapiens]
          Length = 925

 Score =  957 bits (2474), Expect = 0.0
 Identities = 458/856 (53%), Positives = 593/856 (69%), Gaps = 14/856 (1%)

Query: 21  YKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFDASFRGLENCRCDVACKDRGD 80
           YK+  +VL   ++   LG   GL     ++  SC+ +CF+ +F    NCRCD AC + G+
Sbjct: 75  YKVLSLVLSVCVLTTILGCIFGLKPSCAKEVKSCKGRCFERTFG---NCRCDAACVELGN 131

Query: 81  CCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCLQRKDCCADYKSVCQGETSWL 140
           CC D+++TC+E   IW CNKFRCGE RL  SLC+CSDDC  + DCC +Y SVCQGE SW+
Sbjct: 132 CCLDYQETCIEPEHIWTCNKFRCGEKRLTRSLCACSDDCKDKGDCCINYSSVCQGEKSWV 191

Query: 141 EENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAM 200
           EE C++  + QCP GF+ PP +LFS+DGFRAEYL+TW  L+P I+KLK CG ++K MR +
Sbjct: 192 EEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTKNMRPV 251

Query: 201 YPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQPMWLTAM 260
           YPTKTFPNHY+IVTGLYPESHGIIDN MYD  +N +FSL SKE+ NP W+ G+P+W+TA 
Sbjct: 252 YPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAK 311

Query: 261 YQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERISTLLKWLDLPKAERPRFYTMY 320
           YQGLK+ T+FWPGS+V ING FP IY  YNGSVPFEERI  +L+WL LPK ERP FYT+Y
Sbjct: 312 YQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLY 371

Query: 321 FEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQTYC 380
            EEPDSSGH+ GPVS+ VIKALQ VD   GMLM+GLK+ NLH C+N+IL++DHGM+Q  C
Sbjct: 372 LEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSC 431

Query: 381 NKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYL 440
            K  Y+  Y   +    +  GPA R+R  ++P  ++SFN E I RNLSCR+P+QHFKPYL
Sbjct: 432 KKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHFKPYL 491

Query: 441 TPDLPKRLHYAKNVRIDKVHLFVDQQW-LAVRSKSNTNCGGGNHGYNNEFRSMEAIFLAH 499
              LPKRLH+AK+ RI+ +  ++D QW LA+       CG G HG +N F +M+A+F+ +
Sbjct: 492 KHFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNVFSNMQALFVGY 551

Query: 500 GPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLNHLLKVPFYEPSHAEEVSKF 559
           GP FK   E + FENIEVYNLMCDLL + PAPNNGTHGSLNHLLK P Y P H +EV   
Sbjct: 552 GPGFKHGIEADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLLKNPVYTPKHPKEVHPL 611

Query: 560 SVCGFANPLPTESLDCFCPHLQNSTQLEQVNQMLNLTQEEITATVKVNLPFGRPRVLQKN 619
             C F    P ++L C C    +   +E      NLT  E        LP+GRPRVLQK 
Sbjct: 612 VQCPFTRN-PRDNLGCSCN--PSILPIEDFQTQFNLTVAEEKIIKHETLPYGRPRVLQKE 668

Query: 620 VDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPTVPDCLRADVRVPPSESQKC 679
              CLL   +++SG+ + + MP+W+SYTV +  + S       +CL  D R+P S   KC
Sbjct: 669 NTICLLSQHQFMSGYSQDILMPLWTSYTVDR--NDSFSTEDFSNCLYQDFRIPLSPVHKC 726

Query: 680 SFYLADKNITHGFLYPPASNRTSDSQY-DALITSNLVPMYEEFRKMWDYFHSVLLIKHAT 738
           SFY  +  +++GFL PP  N+ S   Y +AL+T+N+VPMY+ F+ +W YFH  LL K+A 
Sbjct: 727 SFYKNNTKVSYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFHDTLLRKYAE 786

Query: 739 ERNGVNVVSGPIFDYNYDGHFDAPDEITKH---LANTDVPIPTHYFVVLTSCKNKSHTPE 795
           ERNGVNVVSGP+FD++YDG  D+ + + +    + N ++ IPTH+F+VLTSCK+ S TP 
Sbjct: 787 ERNGVNVVSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKDTSQTPL 846

Query: 796 NCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRDVELLTGLDFYQDKV 855
           +C   LD L FI+PHR  N ESC  GK ++ WVEE    H AR+ DVE +TGL FYQ + 
Sbjct: 847 HCEN-LDTLAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSFYQQRK 905

Query: 856 QPVSEILQLKTYLPTF 871
           +PVS+IL+LKT+LPTF
Sbjct: 906 EPVSDILKLKTHLPTF 921


>gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens]
          Length = 863

 Score =  796 bits (2057), Expect = 0.0
 Identities = 377/835 (45%), Positives = 541/835 (64%), Gaps = 39/835 (4%)

Query: 52  GSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEAS 111
           GSC+ +CF+    G  +CRCD  CK    CC DF++ C+++ R W C K RCGE R E +
Sbjct: 57  GSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEEN 116

Query: 112 LCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRA 171
            C CS+DCL R DCC +Y+ VC+GE+ W++++C+  + ++CP GF  PP+I+FS+DGFRA
Sbjct: 117 ACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRA 176

Query: 172 EYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDV 231
            Y+     +MPNI KL++CG HS YMR +YPTKTFPN YT+ TGLYPESHGI+ N+MYD 
Sbjct: 177 SYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDP 236

Query: 232 NLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNG 291
             +  F L  +E+ N  WW GQP+W+TA  QG+KA T+FW                  + 
Sbjct: 237 VFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SV 278

Query: 292 SVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGM 351
            +P E RI T+L+WL LP  ERP  Y  Y E+PD SGH  GP    +   L+ +D   G 
Sbjct: 279 VIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQ 338

Query: 352 LMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIR---A 408
           LM+GLKQ  LH CVN+I + DHGM+   C++ E++++Y   ++   +  G   RIR   +
Sbjct: 339 LMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFS 398

Query: 409 HNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQW- 467
           +N  +D      + I+ NL+C+KPDQHFKPYL   LPKRLHYA N RI+ +HL V+++W 
Sbjct: 399 NNAKYD-----PKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWH 453

Query: 468 -----LAVRSKSNTNC-GGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLM 521
                L V  K +  C   G+HG++N+  SM+ +F+ +G +FK KT+V PFENIE+YN+M
Sbjct: 454 VARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVM 513

Query: 522 CDLLRIQPAPNNGTHGSLNHLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFC-PHL 580
           CDLL ++PAPNNGTHGSLNHLL+   + P+  EEV++ +  G         L C C   +
Sbjct: 514 CDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKV 573

Query: 581 QNSTQLEQVNQMLNLTQEEITATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRM 640
           +   +L+++N+ L+       +T + +L +GRP VL +   + +LYH ++ SG+ +   M
Sbjct: 574 EPKNKLDELNKRLHTK----GSTEERHLLYGRPAVLYR-TRYDILYHTDFESGYSEIFLM 628

Query: 641 PMWSSYTVPQLGDTSPLPPTVPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNR 700
           P+W+SYTV +  + S +P  +  C+R DVRV PS SQ C  Y  DK +++GFL+PP  + 
Sbjct: 629 PLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSS 688

Query: 701 TSDSQYDALITSNLVPMYEEFRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFD 760
           + +++YDA + +N+VPMY  F+++W+YF  VL+ K+A+ERNGVNV+SGPIFDY+YDG  D
Sbjct: 689 SPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHD 748

Query: 761 APDEITKHLANTDVPIPTHYFVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPE 820
             D+I +++  + +P+PTHY+ ++TSC + +   + C G L V  FI+PHRP N ESC  
Sbjct: 749 TEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNS 808

Query: 821 GKPEALWVEERFTAHIARVRDVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI 875
            + E+ WVEE    H ARVRD+E LT LDF++   +   EIL LKTYL T+E+ I
Sbjct: 809 SEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 863


>gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens]
          Length = 888

 Score =  790 bits (2041), Expect = 0.0
 Identities = 379/856 (44%), Positives = 542/856 (63%), Gaps = 56/856 (6%)

Query: 52  GSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEAS 111
           GSC+ +CF+    G  +CRCD  CK    CC DF++ C+++ R W C K RCGE R E +
Sbjct: 57  GSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEEN 116

Query: 112 LCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRA 171
            C CS+DCL R DCC +Y+ VC+GE+ W++++C+  + ++CP GF  PP+I+FS+DGFRA
Sbjct: 117 ACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRA 176

Query: 172 EYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDV 231
            Y+     +MPNI KL++CG HS YMR +YPTKTFPN YT+ TGLYPESHGI+ N+MYD 
Sbjct: 177 SYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDP 236

Query: 232 NLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNG 291
             +  F L  +E+ N  WW GQP+W+TA  QG+KA T+FW                  + 
Sbjct: 237 VFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SV 278

Query: 292 SVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGM 351
            +P E RI T+L+WL LP  ERP  Y  Y E+PD SGH  GP    +   L+ +D   G 
Sbjct: 279 VIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQ 338

Query: 352 LMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIR---A 408
           LM+GLKQ  LH CVN+I + DHGM+   C++ E++++Y   ++   +  G   RIR   +
Sbjct: 339 LMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFS 398

Query: 409 HNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQW- 467
           +N  +D      + I+ NL+C+KPDQHFKPYL   LPKRLHYA N RI+ +HL V+++W 
Sbjct: 399 NNAKYD-----PKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWH 453

Query: 468 -----LAVRSKSNTNC-GGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLM 521
                L V  K +  C   G+HG++N+  SM+ +F+ +G +FK KT+V PFENIE+YN+M
Sbjct: 454 VARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVM 513

Query: 522 CDLLRIQPAPNNGTHGSLNHLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFC-PHL 580
           CDLL ++PAPNNGTHGSLNHLL+   + P+  EEV++ +  G         L C C   +
Sbjct: 514 CDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKV 573

Query: 581 QNSTQLEQVNQML-----------------NLTQEEITATVKV----NLPFGRPRVLQKN 619
           +   +L+++N+ L                 N  +E I    +     +L +GRP VL + 
Sbjct: 574 EPKNKLDELNKRLHTKGSTEAETRKFRGSRNENKENINGNFEPRKERHLLYGRPAVLYR- 632

Query: 620 VDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPTVPDCLRADVRVPPSESQKC 679
             + +LYH ++ SG+ +   MP+W+SYTV +  + S +P  +  C+R DVRV PS SQ C
Sbjct: 633 TRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNC 692

Query: 680 SFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEEFRKMWDYFHSVLLIKHATE 739
             Y  DK +++GFL+PP  + + +++YDA + +N+VPMY  F+++W+YF  VL+ K+A+E
Sbjct: 693 LAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASE 752

Query: 740 RNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHYFVVLTSCKNKSHTPENCPG 799
           RNGVNV+SGPIFDY+YDG  D  D+I +++  + +P+PTHY+ ++TSC + +   + C G
Sbjct: 753 RNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDG 812

Query: 800 WLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRDVELLTGLDFYQDKVQPVS 859
            L V  FI+PHRP N ESC   + E+ WVEE    H ARVRD+E LT LDF++   +   
Sbjct: 813 PLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYP 872

Query: 860 EILQLKTYLPTFETTI 875
           EIL LKTYL T+E+ I
Sbjct: 873 EILTLKTYLHTYESEI 888


>gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens]
          Length = 915

 Score =  771 bits (1991), Expect = 0.0
 Identities = 378/887 (42%), Positives = 544/887 (61%), Gaps = 91/887 (10%)

Query: 52  GSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEAS 111
           GSC+ +CF+    G  +CRCD  CK    CC DF++ C+++ R W C K RCGE R E +
Sbjct: 57  GSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEEN 116

Query: 112 LCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRA 171
            C CS+DCL R DCC +Y+ VC+GE+ W++++C+  + ++CP GF  PP+I+FS+DGFRA
Sbjct: 117 ACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRA 176

Query: 172 EYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDV 231
            Y+     +MPNI KL++CG HS YMR +YPTKTFPN YT+ TGLYPESHGI+ N+MYD 
Sbjct: 177 SYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDP 236

Query: 232 NLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNG 291
             +  F L  +E+ N  WW GQP+W+TA  QG+KA T+FW                  + 
Sbjct: 237 VFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SV 278

Query: 292 SVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGG------------------- 332
            +P E RI T+L+WL LP  ERP  Y  Y E+PD SGH  G                   
Sbjct: 279 VIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEESSYGSPFTPAKRP 338

Query: 333 ------------PVSA---------------------RVIKALQVVDHAFGMLMEGLKQR 359
                       PV+                      ++   L+ +D   G LM+GLKQ 
Sbjct: 339 KRKVAPKRRQERPVAPPKKRRRKIHRMDHYAAETRQDKMTNPLREIDKIVGQLMDGLKQL 398

Query: 360 NLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRA---HNIPHDFF 416
            LH CVN+I + DHGM+   C++ E++++Y   ++   +  G   RIR+   +N  +D  
Sbjct: 399 KLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYD-- 456

Query: 417 SFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQW------LAV 470
               + I+ NL+C+KPDQHFKPYL   LPKRLHYA N RI+ +HL V+++W      L V
Sbjct: 457 ---PKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDV 513

Query: 471 RSKSNTNCG-GGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQP 529
             K +  C   G+HG++N+  SM+ +F+ +G +FK KT+V PFENIE+YN+MCDLL ++P
Sbjct: 514 YKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKP 573

Query: 530 APNNGTHGSLNHLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPH-LQNSTQLEQ 588
           APNNGTHGSLNHLL+   + P+  EEV++ +  G         L C C   ++   +L++
Sbjct: 574 APNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDE 633

Query: 589 VNQMLNLTQEEITATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTV 648
           +N+ L+       +T + +L +GRP VL +   + +LYH ++ SG+ +   MP+W+SYTV
Sbjct: 634 LNKRLHTKG----STEERHLLYGRPAVLYRT-RYDILYHTDFESGYSEIFLMPLWTSYTV 688

Query: 649 PQLGDTSPLPPTVPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDA 708
            +  + S +P  +  C+R DVRV PS SQ C  Y  DK +++GFL+PP  + + +++YDA
Sbjct: 689 SKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDA 748

Query: 709 LITSNLVPMYEEFRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKH 768
            + +N+VPMY  F+++W+YF  VL+ K+A+ERNGVNV+SGPIFDY+YDG  D  D+I ++
Sbjct: 749 FLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQY 808

Query: 769 LANTDVPIPTHYFVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWV 828
           +  + +P+PTHY+ ++TSC + +   + C G L V  FI+PHRP N ESC   + E+ WV
Sbjct: 809 VEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWV 868

Query: 829 EERFTAHIARVRDVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI 875
           EE    H ARVRD+E LT LDF++   +   EIL LKTYL T+E+ I
Sbjct: 869 EELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 915


>gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5
           (putative function) [Homo sapiens]
          Length = 477

 Score =  241 bits (614), Expect = 3e-63
 Identities = 134/388 (34%), Positives = 214/388 (55%), Gaps = 15/388 (3%)

Query: 157 DLPPVILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGL 216
           D   V+L S DGFR +YLY   T  P+ + +   G+H K +  ++ TKT+PNHYT+VTGL
Sbjct: 26  DQQKVLLVSFDGFRWDYLYKVPT--PHFHYIMKYGVHVKQVTNVFITKTYPNHYTLVTGL 83

Query: 217 YPESHGIIDNNMYDVNLNKNFSLSSKE-QNNPAWWHGQPMWLTAMYQGLKAATYFWPGSE 275
           + E+HGI+ N+M+D   NK+FSL      ++  W    P+W+T    G  +    WPG++
Sbjct: 84  FAENHGIVANDMFDPIRNKSFSLDHMNIYDSKFWEEATPIWITNQRAGHTSGAAMWPGTD 143

Query: 276 VAINGSFPSIYMPYNGSVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVS 335
           V I+  FP+ YMPYN SV FE+R++ +++W      E      +Y+E+PD  GH  GP S
Sbjct: 144 VKIHKRFPTHYMPYNESVSFEDRVAKIIEW--FTSKEPINLGLLYWEDPDDMGHHLGPDS 201

Query: 336 ARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINF 395
             +   +  +D   G L++ LK+  L N +N+I+ +DHGM Q    ++  +  Y  + ++
Sbjct: 202 PLMGPVISDIDKKLGYLIQMLKKAKLWNTLNLIITSDHGMTQCSEERLIELDQYLDKDHY 261

Query: 396 FYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVR 455
             + + P   I    +P +      +E+   L+   P  +   Y   D+P+R HY  N R
Sbjct: 262 TLIDQSPVAAI----LPKE---GKFDEVYEALTHAHP--NLTVYKKEDVPERWHYKYNSR 312

Query: 456 IDKVHLFVDQQWLAVRSKSNTNCGGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENI 515
           I  +    D+ W  +++KS+ +   GNHGY+N    M  IFLAHGP+F++    E   + 
Sbjct: 313 IQPIIAVADEGWHILQNKSD-DFLLGNHGYDNALADMHPIFLAHGPAFRKNFSKEAMNST 371

Query: 516 EVYNLMCDLLRIQPAPNNGTHGSLNHLL 543
           ++Y L+C LL I   P+NG+  ++  LL
Sbjct: 372 DLYPLLCHLLNITAMPHNGSFWNVQDLL 399


>gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4
           (putative function) [Homo sapiens]
          Length = 453

 Score =  238 bits (606), Expect = 2e-62
 Identities = 137/389 (35%), Positives = 213/389 (54%), Gaps = 22/389 (5%)

Query: 159 PPVILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYP 218
           P ++L S DGFRA+YL  ++   P++      G+  ++++ ++ TKTFPNHY+IVTGLY 
Sbjct: 26  PKLLLVSFDGFRADYLKNYE--FPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYE 83

Query: 219 ESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWH-GQPMWLT-AMYQGLKAATYFWPGSEV 276
           ESHGI+ N+MYD    K+FS S+    +P WW+   P+W+T  + +   +A   WPG++V
Sbjct: 84  ESHGIVANSMYDAVTKKHFSDSN--DKDPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDV 141

Query: 277 AINGSFPSIYMPYNGSVPFEERISTLLKWLDLPKAERP-RFYTMYFEEPDSSGHAGGPV- 334
            I+ +  S +M YN SV FEER++ +  WL+   +  P  F T+Y+EEPD+SGH  GP  
Sbjct: 142 PIHDTISSYFMNYNSSVSFEERLNNITMWLN--NSNPPVTFATLYWEEPDASGHKYGPED 199

Query: 335 SARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRIN 394
              + + L+ +D   G L++ LK   L   +N+I+ +DHGM Q   +++  +        
Sbjct: 200 KENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSY 259

Query: 395 FFYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNV 454
           +  +   P   I    +P      N  E+   L    P  H   YL  D+P R +Y  N 
Sbjct: 260 YTLIDLSPVAAI----LP----KINRTEVYNKLKNCSP--HMNVYLKEDIPNRFYYQHND 309

Query: 455 RIDKVHLFVDQQWLAVRSKSNTNCGGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFEN 514
           RI  + L  D+ W  V ++S+     G+HGY+N   SM     AHGP+F +  +      
Sbjct: 310 RIQPIILVADEGWTIVLNESSQKL--GDHGYDNSLPSMHPFLAAHGPAFHKGYKHSTINI 367

Query: 515 IEVYNLMCDLLRIQPAPNNGTHGSLNHLL 543
           +++Y +MC +L ++P PNNGT G    LL
Sbjct: 368 VDIYPMMCHILGLKPHPNNGTFGHTKCLL 396


>gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6
           [Homo sapiens]
          Length = 440

 Score =  190 bits (483), Expect = 4e-48
 Identities = 122/413 (29%), Positives = 200/413 (48%), Gaps = 31/413 (7%)

Query: 161 VILFSMDGFRAEYLYTWDTL--MPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYP 218
           +++F +DGFR++Y+   + L  +P   ++ + G+   Y+   +P+ ++PN+YT++TG + 
Sbjct: 26  LLVFLLDGFRSDYISD-EALESLPGFKEIVSRGVKVDYLTPDFPSLSYPNYYTLMTGRHC 84

Query: 219 ESHGIIDNNMYDVNLNKNFSLS-SKEQNNPAWWHG-QPMWLTAMYQGLKAATYFWPGSEV 276
           E H +I N M+D   NK+F +  +K+   P WW+G +P+W+T      K   Y+WPG EV
Sbjct: 85  EVHQMIGNYMWDPTTNKSFDIGVNKDSLMPLWWNGSEPLWVTLTKAKRKVYMYYWPGCEV 144

Query: 277 AINGSFPSIYMPYNGSVPFEERISTLLK-WLDLPKAERPRFYTMYFEEPDSSGHAGGPVS 335
            I G  P+  + Y  +VP +   +  +   LD  K+ R     +Y E  D  GH  GP S
Sbjct: 145 EILGVRPTYCLEYK-NVPTDINFANAVSDALDSFKSGRADLAAIYHERIDVEGHHYGPAS 203

Query: 336 ARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINF 395
            +   AL+ VD     + + +++R L + +N+I+ +DHGM   +        + +  +N 
Sbjct: 204 PQRKDALKAVDTVLKYMTKWIQERGLQDRLNVIIFSDHGMTDIFWMDKVIELNKYISLND 263

Query: 396 FYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVR 455
               +   P +     P         EI   LS     +H   Y    +P R +Y K   
Sbjct: 264 LQQVKDRGPVVSLWPAPG-----KHSEIYNKLSTV---EHMTVYEKEAIPSRFYYKKGKF 315

Query: 456 IDKVHLFVDQQWLAVRSKSNT----NCGG-------GNHGYNNEFRSMEAIFLAHGPSFK 504
           +  + L  D+ W    ++       N  G       G HGY+NE   M  IFLA GP FK
Sbjct: 316 VSPLTLVADEGWFITENREMLPFWMNSTGRREGWQRGWHGYDNELMDMRGIFLAFGPDFK 375

Query: 505 EKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLNHLLK-----VPFYEPSH 552
                 P  +++VYN+MC+++ I P PNNG+   +  +LK      P   PSH
Sbjct: 376 SNFRAAPIRSVDVYNVMCNVVGITPLPNNGSWSRVMCMLKGRASTAPPVWPSH 428


>gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7
           [Homo sapiens]
          Length = 458

 Score =  187 bits (474), Expect = 5e-47
 Identities = 126/398 (31%), Positives = 192/398 (48%), Gaps = 32/398 (8%)

Query: 161 VILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPES 220
           ++L S DGFR  Y    DT  PN++ +   G+ ++YM   + T T P H+T+VTG Y E+
Sbjct: 33  LLLVSFDGFRWNYDQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIEN 90

Query: 221 HGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQ-PMWLTAMYQGLKAATYFWPGSEVAIN 279
           HG++ N  Y+          +       W +G  P+W+TA  QGL+A ++F+PG  V   
Sbjct: 91  HGVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQ 150

Query: 280 GSFPS------IYMPYNGSVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGP 333
           G   +      I   Y     +   I T++ W      E     T+YF EPDS+GH  GP
Sbjct: 151 GVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFT---EEDLDLVTLYFGEPDSTGHRYGP 207

Query: 334 VSARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGM--------DQTYCNKMEY 385
            S    + ++ VD   G L E + + +L + +N+I+ +DHGM        D    +K   
Sbjct: 208 ESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFPN 267

Query: 386 MTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLP 445
            T  F  I F  +  GP   +    +P +      E++   L    P  H   Y     P
Sbjct: 268 FT--FRDIEFELLDYGPNGML----LPKEG---RLEKVYDALKDAHPKLHV--YKKEAFP 316

Query: 446 KRLHYAKNVRIDKVHLFVDQQWLAVRSKSNTNCGGGNHGYNNEFRSMEAIFLAHGPSFKE 505
           +  HYA N R+  + ++ D  ++ +  + N     G HG++N+   M+ IF A GPSF+ 
Sbjct: 317 EAFHYANNPRVTPLLMYSDLGYV-IHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRA 375

Query: 506 KTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLNHLL 543
             EVEPFE++ VY LMC LL I P  N+G   +L  +L
Sbjct: 376 GLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPML 413


>gi|239755573 PREDICTED: similar to ectonucleotide
           pyrophosphatase/phosphodiesterase 5 (putative function)
           [Homo sapiens]
          Length = 661

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 63/275 (22%), Positives = 111/275 (40%), Gaps = 51/275 (18%)

Query: 316 FYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGM 375
           F T+Y+ +PD+ GH   P +      +Q +D     L+   ++ +L +   +I+  DHGM
Sbjct: 281 FVTLYYRQPDNVGHRFKPEAENRKLMIQQLDRTIWYLVGATEKHSLQS-PQVIITXDHGM 339

Query: 376 ----DQTYCNKMEYMTDYFPRINFFYM----YEG---PAPRIRAHNIPHDFFSFNSEEIV 424
                +   NK+  +++Y    ++       Y G   P P++              E + 
Sbjct: 340 MTVKKRPNVNKIX-LSNYIKFRDWVKFDIVGYGGFGLPLPKLG-----------QEEALY 387

Query: 425 RNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQWLAVRSKSNT-------- 476
           + L    P  H   Y   + P+  H AK+ R+  + ++ +  +  + S   T        
Sbjct: 388 QALKNAHPHLHI--YKKEEFPEHFHLAKHDRVLPIVMYANSSYRYLDSSMRTFNETRTFP 445

Query: 477 ---------------NC-GGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNL 520
                           C   G+HG++N    M+ IF   GP FK+    E F +I +Y  
Sbjct: 446 TDQPDSLREQDARIIMCFNKGSHGFDNVLMDMKTIFRDFGPDFKKNGLAETFNSIHIYPF 505

Query: 521 MCDLLRIQPAPNNGTHGSLNHLLKVPFYEPSHAEE 555
           +C LL + P  +NG+      +L V  Y+   A E
Sbjct: 506 VCKLLGVXPQTHNGSLAVTQEML-VNSYDQQPASE 539



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 37/123 (30%), Positives = 58/123 (47%), Gaps = 12/123 (9%)

Query: 152 CPEGFDLPP-------VILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTK 204
           CP G   PP       ++L S  GFR +     DT  PN++ L   G+ +KY+     T 
Sbjct: 13  CPAGRPPPPREEEHSQLLLISFQGFRWDXDQDVDT--PNMDHLAGEGVKAKYLMPPLVTM 70

Query: 205 TFPNHYTIVTG--LYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHG-QPMWLTAMY 261
           T P H+T + G  L+   H +I N M++  +  N S  + ++      +    +W+TA  
Sbjct: 71  TSPFHFTAMPGKLLWVRDHXVIHNMMFNTEMLWNCSFKTTQKKTQCXDNRVLSLWITAQR 130

Query: 262 QGL 264
           QGL
Sbjct: 131 QGL 133


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 14/115 (12%)

Query: 19  KKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFDASFRGLENCRCDVACKDR 78
           K   I  ++LL++ VI  +           +   SC  +C +   R    C CD  C+  
Sbjct: 4   KTLPIYLLLLLSVFVIQQVSS---------QDLSSCAGRCGEGYSRDA-TCNCDYNCQHY 53

Query: 79  GDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCLQRKDCCADYKSVC 133
            +CC DF+  C       +  K RC E+      C C   C +   CC DY+S C
Sbjct: 54  MECCPDFKRVCTAE----LSCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFC 104



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query: 53  SCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVE 91
           SC+ +CF++  RG E C CD  CK    CC D+E  C E
Sbjct: 69  SCKGRCFESFERGRE-CDCDAQCKKYDKCCPDYESFCAE 106



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 15/37 (40%), Positives = 20/37 (54%)

Query: 102 RCGETRLEASLCSCSDDCLQRKDCCADYKSVCQGETS 138
           RCGE     + C+C  +C    +CC D+K VC  E S
Sbjct: 33  RCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAELS 69


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 14/115 (12%)

Query: 19  KKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFDASFRGLENCRCDVACKDR 78
           K   I  ++LL++ VI  +           +   SC  +C +   R    C CD  C+  
Sbjct: 4   KTLPIYLLLLLSVFVIQQVSS---------QDLSSCAGRCGEGYSRDA-TCNCDYNCQHY 53

Query: 79  GDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCLQRKDCCADYKSVC 133
            +CC DF+  C       +  K RC E+      C C   C +   CC DY+S C
Sbjct: 54  MECCPDFKRVCTAE----LSCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFC 104



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query: 53  SCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVE 91
           SC+ +CF++  RG E C CD  CK    CC D+E  C E
Sbjct: 69  SCKGRCFESFERGRE-CDCDAQCKKYDKCCPDYESFCAE 106



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 15/37 (40%), Positives = 20/37 (54%)

Query: 102 RCGETRLEASLCSCSDDCLQRKDCCADYKSVCQGETS 138
           RCGE     + C+C  +C    +CC D+K VC  E S
Sbjct: 33  RCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAELS 69


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 11/73 (15%)

Query: 19 KKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFDASFRGLENCRCDVACKDR 78
          K   I  ++LL++ VI  +            ++ SC+ +CF++  RG E C CD  CK  
Sbjct: 4  KTLPIYLLLLLSVFVIQQVS----------SQELSCKGRCFESFERGRE-CDCDAQCKKY 52

Query: 79 GDCCWDFEDTCVE 91
            CC D+E  C E
Sbjct: 53 DKCCPDYESFCAE 65



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 13/34 (38%), Positives = 16/34 (47%)

Query: 100 KFRCGETRLEASLCSCSDDCLQRKDCCADYKSVC 133
           K RC E+      C C   C +   CC DY+S C
Sbjct: 30  KGRCFESFERGRECDCDAQCKKYDKCCPDYESFC 63


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 11/73 (15%)

Query: 19 KKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFDASFRGLENCRCDVACKDR 78
          K   I  ++LL++ VI  +            ++ SC+ +CF++  RG E C CD  CK  
Sbjct: 4  KTLPIYLLLLLSVFVIQQVS----------SQELSCKGRCFESFERGRE-CDCDAQCKKY 52

Query: 79 GDCCWDFEDTCVE 91
            CC D+E  C E
Sbjct: 53 DKCCPDYESFCAE 65



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 13/34 (38%), Positives = 16/34 (47%)

Query: 100 KFRCGETRLEASLCSCSDDCLQRKDCCADYKSVC 133
           K RC E+      C C   C +   CC DY+S C
Sbjct: 30  KGRCFESFERGRECDCDAQCKKYDKCCPDYESFC 63


>gi|169217819 PREDICTED: similar to hCG1793095 [Homo sapiens]
          Length = 167

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 2/57 (3%)

Query: 161 VILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLY 217
           ++L S D FR  Y    DT  PN++ +   G+ ++YM   + T T P H+T+VTG Y
Sbjct: 33  LLLVSFDSFRWNYEQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGEY 87


>gi|239756564 PREDICTED: similar to hCG1793095 [Homo sapiens]
          Length = 98

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 2/57 (3%)

Query: 161 VILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLY 217
           ++L S D FR  Y    DT  PN++ +   G+ ++YM   + T T P H+T+VTG Y
Sbjct: 33  LLLVSFDSFRWNYEQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGEY 87


>gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]
          Length = 476

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 15/66 (22%)

Query: 75  CKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDC-LQRKDCCADYKSVC 133
           C++ G CC D +D CV  T  +  N           +LC C   C  +  DCC DYKS C
Sbjct: 57  CRNFG-CCEDRDDGCV--TEFYAAN-----------ALCYCDKFCDRENSDCCPDYKSFC 102

Query: 134 QGETSW 139
           + E  W
Sbjct: 103 REEKEW 108


>gi|5174623 placental protein 11 precursor [Homo sapiens]
          Length = 369

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%)

Query: 53 SCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTC 89
          SC+ +C++A F     C C+  C++ G+CC DFE  C
Sbjct: 48 SCQGRCYEA-FDKHHQCHCNARCQEFGNCCKDFESLC 83


>gi|224451073 endo/exonuclease (5'-3'), endonuclease G-like isoform
           1 precursor [Homo sapiens]
          Length = 368

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 54/250 (21%), Positives = 106/250 (42%), Gaps = 38/250 (15%)

Query: 627 HREYVSGFGKAMRMPMWSSYTVPQ---LGDTSPLPPTVPDC-LRADVRVPPSESQKCSFY 682
           +  +   + +A R+P W    + +   +GD          C  + D  +PP+ S     Y
Sbjct: 77  YTNHALSYDQAKRVPRWVLEHISKSKIMGDADR-----KHCKFKPDPNIPPTFSAFNEDY 131

Query: 683 LADKNITHGFLYPPASNR-TSDSQYDALITSNLVPMYEEFRKMWDYFHSV-LLIKHATER 740
           +     + G + P  +N+ +S +  +    SN+VP  ++F     Y++ + +  +  TER
Sbjct: 132 VGS-GWSRGHMAPAGNNKFSSKAMAETFYLSNIVP--QDFDNNSGYWNRIEMYCRELTER 188

Query: 741 -NGVNVVSGPIFDYNYDGHFDAPDEITKHLANTD-VPIPTHYFVVLTSCKNKSHTPENCP 798
              V VVSGP+      G  D    ++  +   D V +P+H + V+ + ++   T     
Sbjct: 189 FEDVWVVSGPLTLPQTRG--DGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLAL 246

Query: 799 GWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRDVELLTGLDFYQ--DKVQ 856
           G      F++P+             EA+  + + T     ++D+E L+GL F+   D+  
Sbjct: 247 G-----AFVVPN-------------EAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTS 288

Query: 857 PVSEILQLKT 866
            +  I  + T
Sbjct: 289 DIRNICSVDT 298


>gi|224451075 endo/exonuclease (5'-3'), endonuclease G-like isoform
           2 precursor [Homo sapiens]
          Length = 318

 Score = 38.5 bits (88), Expect = 0.027
 Identities = 47/207 (22%), Positives = 91/207 (43%), Gaps = 29/207 (14%)

Query: 666 RADVRVPPSESQKCSFYLADKNITHGFLYPPASNR-TSDSQYDALITSNLVPMYEEFRKM 724
           + D  +PP+ S     Y+     + G + P  +N+ +S +  +    SN+VP  ++F   
Sbjct: 65  KPDPNIPPTFSAFNEDYVGS-GWSRGHMAPAGNNKFSSKAMAETFYLSNIVP--QDFDNN 121

Query: 725 WDYFHSV-LLIKHATER-NGVNVVSGPIFDYNYDGHFDAPDEITKHLANTD-VPIPTHYF 781
             Y++ + +  +  TER   V VVSGP+      G  D    ++  +   D V +P+H +
Sbjct: 122 SGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRG--DGKKIVSYQVIGEDNVAVPSHLY 179

Query: 782 VVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRD 841
            V+ + ++   T     G      F++P+             EA+  + + T     ++D
Sbjct: 180 KVILARRSSVSTEPLALG-----AFVVPN-------------EAIGFQPQLTEFQVSLQD 221

Query: 842 VELLTGLDFYQ--DKVQPVSEILQLKT 866
           +E L+GL F+   D+   +  I  + T
Sbjct: 222 LEKLSGLVFFPHLDRTSDIRNICSVDT 248


>gi|169209673 PREDICTED: similar to hCG2042391 [Homo sapiens]
          Length = 129

 Score = 38.1 bits (87), Expect = 0.036
 Identities = 26/108 (24%), Positives = 45/108 (41%), Gaps = 9/108 (8%)

Query: 262 QGLKAATYFWPGSEVAINGS------FPSIYMPYNGSVPFEERISTLLKWLDLPKAERPR 315
           QG KAA+  +       +G         S   P +    + E I T++ W      +   
Sbjct: 14  QGNKAASSHYSRGGAKYDGEAVKRSLVESYTHPNSNETEWRENIDTVMNWFTKEDFD--- 70

Query: 316 FYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHN 363
           F T+ + EPD+ GH  GP +      +Q +D   G L+   ++ +L +
Sbjct: 71  FVTLCYREPDNVGHRFGPEAENRKLMIQQIDRTIGYLVGATEKHSLQS 118


>gi|169210658 PREDICTED: similar to hCG2042391 [Homo sapiens]
          Length = 129

 Score = 38.1 bits (87), Expect = 0.036
 Identities = 26/108 (24%), Positives = 45/108 (41%), Gaps = 9/108 (8%)

Query: 262 QGLKAATYFWPGSEVAINGS------FPSIYMPYNGSVPFEERISTLLKWLDLPKAERPR 315
           QG KAA+  +       +G         S   P +    + E I T++ W      +   
Sbjct: 14  QGNKAASSHYSRGGAKYDGEAVKRSLVESYTHPNSNETEWRENIDTVMNWFTKEDFD--- 70

Query: 316 FYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHN 363
           F T+ + EPD+ GH  GP +      +Q +D   G L+   ++ +L +
Sbjct: 71  FVTLCYREPDNVGHRFGPEAENRKLMIQQIDRTIGYLVGATEKHSLQS 118


>gi|169210188 PREDICTED: similar to hCG2042391 [Homo sapiens]
          Length = 129

 Score = 38.1 bits (87), Expect = 0.036
 Identities = 26/108 (24%), Positives = 45/108 (41%), Gaps = 9/108 (8%)

Query: 262 QGLKAATYFWPGSEVAINGS------FPSIYMPYNGSVPFEERISTLLKWLDLPKAERPR 315
           QG KAA+  +       +G         S   P +    + E I T++ W      +   
Sbjct: 14  QGNKAASSHYSRGGAKYDGEAVKRSLVESYTHPNSNETEWRENIDTVMNWFTKEDFD--- 70

Query: 316 FYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHN 363
           F T+ + EPD+ GH  GP +      +Q +D   G L+   ++ +L +
Sbjct: 71  FVTLCYREPDNVGHRFGPEAENRKLMIQQIDRTIGYLVGATEKHSLQS 118


>gi|239743493 PREDICTED: hypothetical protein XP_002342862 [Homo
           sapiens]
          Length = 169

 Score = 37.4 bits (85), Expect = 0.061
 Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 3/76 (3%)

Query: 288 PYNGSVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDH 347
           P +     +E I T++ W      +   F T+ + EPD+ GH  GP + +    +Q +D 
Sbjct: 86  PSSNETERKENIDTVMNWFTKEDFD---FVTLCYREPDNVGHRFGPEAEKRKLMIQQIDR 142

Query: 348 AFGMLMEGLKQRNLHN 363
             G L+   ++ +L +
Sbjct: 143 TIGYLVGATEKHSLQS 158


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 37.0 bits (84), Expect = 0.080
 Identities = 31/119 (26%), Positives = 45/119 (37%), Gaps = 28/119 (23%)

Query: 54   CRKKCFDASFRGLENCRC---------DVACKDRGDCCWDFEDTCVESTR-IWMCNKFRC 103
            C   C +A   G  +C C         D  C+D  +C WD    C E  R + +   +RC
Sbjct: 3454 CSHACLNAP--GRFSCTCPTGFALAWDDRNCRDVDECAWD-AHLCREGQRCVNLLGSYRC 3510

Query: 104  ------GETRLEASLCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGF 156
                  G    + + C   D+CL+  D C  Y  +C        EN     +  CP G+
Sbjct: 3511 LPDCGPGFRVADGAGCEDVDECLEGLDDC-HYNQLC--------ENTPGGHRCSCPRGY 3560


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 37.0 bits (84), Expect = 0.080
 Identities = 31/119 (26%), Positives = 45/119 (37%), Gaps = 28/119 (23%)

Query: 54   CRKKCFDASFRGLENCRC---------DVACKDRGDCCWDFEDTCVESTR-IWMCNKFRC 103
            C   C +A   G  +C C         D  C+D  +C WD    C E  R + +   +RC
Sbjct: 4645 CSHACLNAP--GRFSCTCPTGFALAWDDRNCRDVDECAWD-AHLCREGQRCVNLLGSYRC 4701

Query: 104  ------GETRLEASLCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGF 156
                  G    + + C   D+CL+  D C  Y  +C        EN     +  CP G+
Sbjct: 4702 LPDCGPGFRVADGAGCEDVDECLEGLDDC-HYNQLC--------ENTPGGHRCSCPRGY 4751


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score = 37.0 bits (84), Expect = 0.080
 Identities = 31/119 (26%), Positives = 45/119 (37%), Gaps = 28/119 (23%)

Query: 54   CRKKCFDASFRGLENCRC---------DVACKDRGDCCWDFEDTCVESTR-IWMCNKFRC 103
            C   C +A   G  +C C         D  C+D  +C WD    C E  R + +   +RC
Sbjct: 3363 CSHACLNAP--GRFSCTCPTGFALAWDDRNCRDVDECAWD-AHLCREGQRCVNLLGSYRC 3419

Query: 104  ------GETRLEASLCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGF 156
                  G    + + C   D+CL+  D C  Y  +C        EN     +  CP G+
Sbjct: 3420 LPDCGPGFRVADGAGCEDVDECLEGLDDC-HYNQLC--------ENTPGGHRCSCPRGY 3469


>gi|10092665 sushi domain containing 2 [Homo sapiens]
          Length = 822

 Score = 37.0 bits (84), Expect = 0.080
 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 5/60 (8%)

Query: 32 LVIMSLGLGLGLGLRKLEKQGSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVE 91
          L++++  LG G G    + Q SC  +C   +  G   C C   C   G CC DF D C+E
Sbjct: 10 LLLLATALGPGPG-PTADAQESCSMRC--GALDG--PCSCHPTCSGLGTCCLDFRDFCLE 64


>gi|187608446 phosphatidylinositol glycan anchor biosynthesis, class
           G isoform 1 [Homo sapiens]
          Length = 983

 Score = 35.4 bits (80), Expect = 0.23
 Identities = 52/237 (21%), Positives = 87/237 (36%), Gaps = 38/237 (16%)

Query: 158 LPP-----VILFSMDGFRAEYLYTWDTL--MPNINKLKTCGI-HSKYMRAMYPTKTFPNH 209
           LPP     V++  +D  R ++++    +  MP    L   G  HS    A  PT T P  
Sbjct: 60  LPPPLFSKVVIVLIDALRDDFVFGSKGVKFMPYTTYLVEKGASHSFVAEAKPPTVTMPRI 119

Query: 210 YTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATY 269
             ++TG  P    +I N      L  +    +K       ++G   W+            
Sbjct: 120 KALMTGSLPGFVDVIRNLNSPALLEDSVIRQAKAAGKRIVFYGDETWVKL---------- 169

Query: 270 FWPGSEVAINGSFPSIYMPYNGSVPF-----EERISTLLKWLD-LPKAERPRFYTMYFEE 323
                       FP  ++ Y+G+  F      E  + + + LD + K        +++  
Sbjct: 170 ------------FPKHFVEYDGTTSFFVSDYTEVDNNVTRHLDKVLKRGDWDILILHYLG 217

Query: 324 PDSSGHAGGPVSARVIKALQVVDHAFGMLMEGL--KQRNLHNCVNIILLADHGMDQT 378
            D  GH  GP S  + + L  +D     +   L  K+R       ++L  DHGM +T
Sbjct: 218 LDHIGHISGPNSPLIGQKLSEMDSVLMKIHTSLQSKERETPLPNLLVLCGDHGMSET 274


>gi|187608438 phosphatidylinositol glycan anchor biosynthesis, class
           G isoform 2 [Homo sapiens]
          Length = 975

 Score = 35.4 bits (80), Expect = 0.23
 Identities = 52/237 (21%), Positives = 87/237 (36%), Gaps = 38/237 (16%)

Query: 158 LPP-----VILFSMDGFRAEYLYTWDTL--MPNINKLKTCGI-HSKYMRAMYPTKTFPNH 209
           LPP     V++  +D  R ++++    +  MP    L   G  HS    A  PT T P  
Sbjct: 60  LPPPLFSKVVIVLIDALRDDFVFGSKGVKFMPYTTYLVEKGASHSFVAEAKPPTVTMPRI 119

Query: 210 YTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATY 269
             ++TG  P    +I N      L  +    +K       ++G   W+            
Sbjct: 120 KALMTGSLPGFVDVIRNLNSPALLEDSVIRQAKAAGKRIVFYGDETWVKL---------- 169

Query: 270 FWPGSEVAINGSFPSIYMPYNGSVPF-----EERISTLLKWLD-LPKAERPRFYTMYFEE 323
                       FP  ++ Y+G+  F      E  + + + LD + K        +++  
Sbjct: 170 ------------FPKHFVEYDGTTSFFVSDYTEVDNNVTRHLDKVLKRGDWDILILHYLG 217

Query: 324 PDSSGHAGGPVSARVIKALQVVDHAFGMLMEGL--KQRNLHNCVNIILLADHGMDQT 378
            D  GH  GP S  + + L  +D     +   L  K+R       ++L  DHGM +T
Sbjct: 218 LDHIGHISGPNSPLIGQKLSEMDSVLMKIHTSLQSKERETPLPNLLVLCGDHGMSET 274


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,970,808
Number of Sequences: 37866
Number of extensions: 1802181
Number of successful extensions: 3857
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 3745
Number of HSP's gapped (non-prelim): 89
length of query: 875
length of database: 18,247,518
effective HSP length: 111
effective length of query: 764
effective length of database: 14,044,392
effective search space: 10729915488
effective search space used: 10729915488
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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