BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3 [Homo sapiens] (875 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3 ... 1855 0.0 gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1 ... 957 0.0 gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens] 796 0.0 gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens] 790 0.0 gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens] 771 0.0 gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5 (... 241 3e-63 gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4 (p... 238 2e-62 gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6 [... 190 4e-48 gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7 [... 187 5e-47 gi|239755573 PREDICTED: similar to ectonucleotide pyrophosphatas... 65 2e-10 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 52 2e-06 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 52 2e-06 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 44 5e-04 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 44 5e-04 gi|169217819 PREDICTED: similar to hCG1793095 [Homo sapiens] 44 7e-04 gi|239756564 PREDICTED: similar to hCG1793095 [Homo sapiens] 44 7e-04 gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens] 42 0.002 gi|5174623 placental protein 11 precursor [Homo sapiens] 40 0.007 gi|224451073 endo/exonuclease (5'-3'), endonuclease G-like isofo... 39 0.016 gi|224451075 endo/exonuclease (5'-3'), endonuclease G-like isofo... 39 0.027 gi|169209673 PREDICTED: similar to hCG2042391 [Homo sapiens] 38 0.036 gi|169210658 PREDICTED: similar to hCG2042391 [Homo sapiens] 38 0.036 gi|169210188 PREDICTED: similar to hCG2042391 [Homo sapiens] 38 0.036 gi|239743493 PREDICTED: hypothetical protein XP_002342862 [Homo ... 37 0.061 gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 37 0.080 gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 37 0.080 gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 37 0.080 gi|10092665 sushi domain containing 2 [Homo sapiens] 37 0.080 gi|187608446 phosphatidylinositol glycan anchor biosynthesis, cl... 35 0.23 gi|187608438 phosphatidylinositol glycan anchor biosynthesis, cl... 35 0.23 >gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3 [Homo sapiens] Length = 875 Score = 1855 bits (4804), Expect = 0.0 Identities = 875/875 (100%), Positives = 875/875 (100%) Query: 1 MESTLTLATEQPVKKNTLKKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFD 60 MESTLTLATEQPVKKNTLKKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFD Sbjct: 1 MESTLTLATEQPVKKNTLKKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFD 60 Query: 61 ASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCL 120 ASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCL Sbjct: 61 ASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCL 120 Query: 121 QRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTL 180 QRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTL Sbjct: 121 QRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTL 180 Query: 181 MPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLS 240 MPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLS Sbjct: 181 MPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLS 240 Query: 241 SKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERIS 300 SKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERIS Sbjct: 241 SKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERIS 300 Query: 301 TLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRN 360 TLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRN Sbjct: 301 TLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRN 360 Query: 361 LHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNS 420 LHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNS Sbjct: 361 LHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNS 420 Query: 421 EEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQWLAVRSKSNTNCGG 480 EEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQWLAVRSKSNTNCGG Sbjct: 421 EEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQWLAVRSKSNTNCGG 480 Query: 481 GNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLN 540 GNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLN Sbjct: 481 GNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLN 540 Query: 541 HLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPHLQNSTQLEQVNQMLNLTQEEI 600 HLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPHLQNSTQLEQVNQMLNLTQEEI Sbjct: 541 HLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPHLQNSTQLEQVNQMLNLTQEEI 600 Query: 601 TATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPT 660 TATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPT Sbjct: 601 TATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPT 660 Query: 661 VPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEE 720 VPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEE Sbjct: 661 VPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEE 720 Query: 721 FRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHY 780 FRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHY Sbjct: 721 FRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHY 780 Query: 781 FVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVR 840 FVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVR Sbjct: 781 FVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVR 840 Query: 841 DVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI 875 DVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI Sbjct: 841 DVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI 875 >gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1 [Homo sapiens] Length = 925 Score = 957 bits (2474), Expect = 0.0 Identities = 458/856 (53%), Positives = 593/856 (69%), Gaps = 14/856 (1%) Query: 21 YKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFDASFRGLENCRCDVACKDRGD 80 YK+ +VL ++ LG GL ++ SC+ +CF+ +F NCRCD AC + G+ Sbjct: 75 YKVLSLVLSVCVLTTILGCIFGLKPSCAKEVKSCKGRCFERTFG---NCRCDAACVELGN 131 Query: 81 CCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCLQRKDCCADYKSVCQGETSWL 140 CC D+++TC+E IW CNKFRCGE RL SLC+CSDDC + DCC +Y SVCQGE SW+ Sbjct: 132 CCLDYQETCIEPEHIWTCNKFRCGEKRLTRSLCACSDDCKDKGDCCINYSSVCQGEKSWV 191 Query: 141 EENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAM 200 EE C++ + QCP GF+ PP +LFS+DGFRAEYL+TW L+P I+KLK CG ++K MR + Sbjct: 192 EEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTKNMRPV 251 Query: 201 YPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQPMWLTAM 260 YPTKTFPNHY+IVTGLYPESHGIIDN MYD +N +FSL SKE+ NP W+ G+P+W+TA Sbjct: 252 YPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAK 311 Query: 261 YQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERISTLLKWLDLPKAERPRFYTMY 320 YQGLK+ T+FWPGS+V ING FP IY YNGSVPFEERI +L+WL LPK ERP FYT+Y Sbjct: 312 YQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLY 371 Query: 321 FEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQTYC 380 EEPDSSGH+ GPVS+ VIKALQ VD GMLM+GLK+ NLH C+N+IL++DHGM+Q C Sbjct: 372 LEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSC 431 Query: 381 NKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYL 440 K Y+ Y + + GPA R+R ++P ++SFN E I RNLSCR+P+QHFKPYL Sbjct: 432 KKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHFKPYL 491 Query: 441 TPDLPKRLHYAKNVRIDKVHLFVDQQW-LAVRSKSNTNCGGGNHGYNNEFRSMEAIFLAH 499 LPKRLH+AK+ RI+ + ++D QW LA+ CG G HG +N F +M+A+F+ + Sbjct: 492 KHFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNVFSNMQALFVGY 551 Query: 500 GPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLNHLLKVPFYEPSHAEEVSKF 559 GP FK E + FENIEVYNLMCDLL + PAPNNGTHGSLNHLLK P Y P H +EV Sbjct: 552 GPGFKHGIEADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLLKNPVYTPKHPKEVHPL 611 Query: 560 SVCGFANPLPTESLDCFCPHLQNSTQLEQVNQMLNLTQEEITATVKVNLPFGRPRVLQKN 619 C F P ++L C C + +E NLT E LP+GRPRVLQK Sbjct: 612 VQCPFTRN-PRDNLGCSCN--PSILPIEDFQTQFNLTVAEEKIIKHETLPYGRPRVLQKE 668 Query: 620 VDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPTVPDCLRADVRVPPSESQKC 679 CLL +++SG+ + + MP+W+SYTV + + S +CL D R+P S KC Sbjct: 669 NTICLLSQHQFMSGYSQDILMPLWTSYTVDR--NDSFSTEDFSNCLYQDFRIPLSPVHKC 726 Query: 680 SFYLADKNITHGFLYPPASNRTSDSQY-DALITSNLVPMYEEFRKMWDYFHSVLLIKHAT 738 SFY + +++GFL PP N+ S Y +AL+T+N+VPMY+ F+ +W YFH LL K+A Sbjct: 727 SFYKNNTKVSYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFHDTLLRKYAE 786 Query: 739 ERNGVNVVSGPIFDYNYDGHFDAPDEITKH---LANTDVPIPTHYFVVLTSCKNKSHTPE 795 ERNGVNVVSGP+FD++YDG D+ + + + + N ++ IPTH+F+VLTSCK+ S TP Sbjct: 787 ERNGVNVVSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKDTSQTPL 846 Query: 796 NCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRDVELLTGLDFYQDKV 855 +C LD L FI+PHR N ESC GK ++ WVEE H AR+ DVE +TGL FYQ + Sbjct: 847 HCEN-LDTLAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSFYQQRK 905 Query: 856 QPVSEILQLKTYLPTF 871 +PVS+IL+LKT+LPTF Sbjct: 906 EPVSDILKLKTHLPTF 921 >gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens] Length = 863 Score = 796 bits (2057), Expect = 0.0 Identities = 377/835 (45%), Positives = 541/835 (64%), Gaps = 39/835 (4%) Query: 52 GSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEAS 111 GSC+ +CF+ G +CRCD CK CC DF++ C+++ R W C K RCGE R E + Sbjct: 57 GSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEEN 116 Query: 112 LCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRA 171 C CS+DCL R DCC +Y+ VC+GE+ W++++C+ + ++CP GF PP+I+FS+DGFRA Sbjct: 117 ACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRA 176 Query: 172 EYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDV 231 Y+ +MPNI KL++CG HS YMR +YPTKTFPN YT+ TGLYPESHGI+ N+MYD Sbjct: 177 SYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDP 236 Query: 232 NLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNG 291 + F L +E+ N WW GQP+W+TA QG+KA T+FW + Sbjct: 237 VFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SV 278 Query: 292 SVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGM 351 +P E RI T+L+WL LP ERP Y Y E+PD SGH GP + L+ +D G Sbjct: 279 VIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQ 338 Query: 352 LMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIR---A 408 LM+GLKQ LH CVN+I + DHGM+ C++ E++++Y ++ + G RIR + Sbjct: 339 LMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFS 398 Query: 409 HNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQW- 467 +N +D + I+ NL+C+KPDQHFKPYL LPKRLHYA N RI+ +HL V+++W Sbjct: 399 NNAKYD-----PKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWH 453 Query: 468 -----LAVRSKSNTNC-GGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLM 521 L V K + C G+HG++N+ SM+ +F+ +G +FK KT+V PFENIE+YN+M Sbjct: 454 VARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVM 513 Query: 522 CDLLRIQPAPNNGTHGSLNHLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFC-PHL 580 CDLL ++PAPNNGTHGSLNHLL+ + P+ EEV++ + G L C C + Sbjct: 514 CDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKV 573 Query: 581 QNSTQLEQVNQMLNLTQEEITATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRM 640 + +L+++N+ L+ +T + +L +GRP VL + + +LYH ++ SG+ + M Sbjct: 574 EPKNKLDELNKRLHTK----GSTEERHLLYGRPAVLYR-TRYDILYHTDFESGYSEIFLM 628 Query: 641 PMWSSYTVPQLGDTSPLPPTVPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNR 700 P+W+SYTV + + S +P + C+R DVRV PS SQ C Y DK +++GFL+PP + Sbjct: 629 PLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSS 688 Query: 701 TSDSQYDALITSNLVPMYEEFRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFD 760 + +++YDA + +N+VPMY F+++W+YF VL+ K+A+ERNGVNV+SGPIFDY+YDG D Sbjct: 689 SPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHD 748 Query: 761 APDEITKHLANTDVPIPTHYFVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPE 820 D+I +++ + +P+PTHY+ ++TSC + + + C G L V FI+PHRP N ESC Sbjct: 749 TEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNS 808 Query: 821 GKPEALWVEERFTAHIARVRDVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI 875 + E+ WVEE H ARVRD+E LT LDF++ + EIL LKTYL T+E+ I Sbjct: 809 SEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 863 >gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens] Length = 888 Score = 790 bits (2041), Expect = 0.0 Identities = 379/856 (44%), Positives = 542/856 (63%), Gaps = 56/856 (6%) Query: 52 GSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEAS 111 GSC+ +CF+ G +CRCD CK CC DF++ C+++ R W C K RCGE R E + Sbjct: 57 GSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEEN 116 Query: 112 LCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRA 171 C CS+DCL R DCC +Y+ VC+GE+ W++++C+ + ++CP GF PP+I+FS+DGFRA Sbjct: 117 ACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRA 176 Query: 172 EYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDV 231 Y+ +MPNI KL++CG HS YMR +YPTKTFPN YT+ TGLYPESHGI+ N+MYD Sbjct: 177 SYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDP 236 Query: 232 NLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNG 291 + F L +E+ N WW GQP+W+TA QG+KA T+FW + Sbjct: 237 VFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SV 278 Query: 292 SVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGM 351 +P E RI T+L+WL LP ERP Y Y E+PD SGH GP + L+ +D G Sbjct: 279 VIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQ 338 Query: 352 LMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIR---A 408 LM+GLKQ LH CVN+I + DHGM+ C++ E++++Y ++ + G RIR + Sbjct: 339 LMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFS 398 Query: 409 HNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQW- 467 +N +D + I+ NL+C+KPDQHFKPYL LPKRLHYA N RI+ +HL V+++W Sbjct: 399 NNAKYD-----PKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWH 453 Query: 468 -----LAVRSKSNTNC-GGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLM 521 L V K + C G+HG++N+ SM+ +F+ +G +FK KT+V PFENIE+YN+M Sbjct: 454 VARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVM 513 Query: 522 CDLLRIQPAPNNGTHGSLNHLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFC-PHL 580 CDLL ++PAPNNGTHGSLNHLL+ + P+ EEV++ + G L C C + Sbjct: 514 CDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKV 573 Query: 581 QNSTQLEQVNQML-----------------NLTQEEITATVKV----NLPFGRPRVLQKN 619 + +L+++N+ L N +E I + +L +GRP VL + Sbjct: 574 EPKNKLDELNKRLHTKGSTEAETRKFRGSRNENKENINGNFEPRKERHLLYGRPAVLYR- 632 Query: 620 VDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPTVPDCLRADVRVPPSESQKC 679 + +LYH ++ SG+ + MP+W+SYTV + + S +P + C+R DVRV PS SQ C Sbjct: 633 TRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNC 692 Query: 680 SFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEEFRKMWDYFHSVLLIKHATE 739 Y DK +++GFL+PP + + +++YDA + +N+VPMY F+++W+YF VL+ K+A+E Sbjct: 693 LAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASE 752 Query: 740 RNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHYFVVLTSCKNKSHTPENCPG 799 RNGVNV+SGPIFDY+YDG D D+I +++ + +P+PTHY+ ++TSC + + + C G Sbjct: 753 RNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDG 812 Query: 800 WLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRDVELLTGLDFYQDKVQPVS 859 L V FI+PHRP N ESC + E+ WVEE H ARVRD+E LT LDF++ + Sbjct: 813 PLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYP 872 Query: 860 EILQLKTYLPTFETTI 875 EIL LKTYL T+E+ I Sbjct: 873 EILTLKTYLHTYESEI 888 >gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens] Length = 915 Score = 771 bits (1991), Expect = 0.0 Identities = 378/887 (42%), Positives = 544/887 (61%), Gaps = 91/887 (10%) Query: 52 GSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEAS 111 GSC+ +CF+ G +CRCD CK CC DF++ C+++ R W C K RCGE R E + Sbjct: 57 GSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEEN 116 Query: 112 LCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRA 171 C CS+DCL R DCC +Y+ VC+GE+ W++++C+ + ++CP GF PP+I+FS+DGFRA Sbjct: 117 ACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRA 176 Query: 172 EYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDV 231 Y+ +MPNI KL++CG HS YMR +YPTKTFPN YT+ TGLYPESHGI+ N+MYD Sbjct: 177 SYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDP 236 Query: 232 NLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNG 291 + F L +E+ N WW GQP+W+TA QG+KA T+FW + Sbjct: 237 VFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SV 278 Query: 292 SVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGG------------------- 332 +P E RI T+L+WL LP ERP Y Y E+PD SGH G Sbjct: 279 VIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEESSYGSPFTPAKRP 338 Query: 333 ------------PVSA---------------------RVIKALQVVDHAFGMLMEGLKQR 359 PV+ ++ L+ +D G LM+GLKQ Sbjct: 339 KRKVAPKRRQERPVAPPKKRRRKIHRMDHYAAETRQDKMTNPLREIDKIVGQLMDGLKQL 398 Query: 360 NLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRA---HNIPHDFF 416 LH CVN+I + DHGM+ C++ E++++Y ++ + G RIR+ +N +D Sbjct: 399 KLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYD-- 456 Query: 417 SFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQW------LAV 470 + I+ NL+C+KPDQHFKPYL LPKRLHYA N RI+ +HL V+++W L V Sbjct: 457 ---PKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDV 513 Query: 471 RSKSNTNCG-GGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQP 529 K + C G+HG++N+ SM+ +F+ +G +FK KT+V PFENIE+YN+MCDLL ++P Sbjct: 514 YKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKP 573 Query: 530 APNNGTHGSLNHLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPH-LQNSTQLEQ 588 APNNGTHGSLNHLL+ + P+ EEV++ + G L C C ++ +L++ Sbjct: 574 APNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDE 633 Query: 589 VNQMLNLTQEEITATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTV 648 +N+ L+ +T + +L +GRP VL + + +LYH ++ SG+ + MP+W+SYTV Sbjct: 634 LNKRLHTKG----STEERHLLYGRPAVLYRT-RYDILYHTDFESGYSEIFLMPLWTSYTV 688 Query: 649 PQLGDTSPLPPTVPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDA 708 + + S +P + C+R DVRV PS SQ C Y DK +++GFL+PP + + +++YDA Sbjct: 689 SKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDA 748 Query: 709 LITSNLVPMYEEFRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKH 768 + +N+VPMY F+++W+YF VL+ K+A+ERNGVNV+SGPIFDY+YDG D D+I ++ Sbjct: 749 FLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQY 808 Query: 769 LANTDVPIPTHYFVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWV 828 + + +P+PTHY+ ++TSC + + + C G L V FI+PHRP N ESC + E+ WV Sbjct: 809 VEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWV 868 Query: 829 EERFTAHIARVRDVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI 875 EE H ARVRD+E LT LDF++ + EIL LKTYL T+E+ I Sbjct: 869 EELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 915 >gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative function) [Homo sapiens] Length = 477 Score = 241 bits (614), Expect = 3e-63 Identities = 134/388 (34%), Positives = 214/388 (55%), Gaps = 15/388 (3%) Query: 157 DLPPVILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGL 216 D V+L S DGFR +YLY T P+ + + G+H K + ++ TKT+PNHYT+VTGL Sbjct: 26 DQQKVLLVSFDGFRWDYLYKVPT--PHFHYIMKYGVHVKQVTNVFITKTYPNHYTLVTGL 83 Query: 217 YPESHGIIDNNMYDVNLNKNFSLSSKE-QNNPAWWHGQPMWLTAMYQGLKAATYFWPGSE 275 + E+HGI+ N+M+D NK+FSL ++ W P+W+T G + WPG++ Sbjct: 84 FAENHGIVANDMFDPIRNKSFSLDHMNIYDSKFWEEATPIWITNQRAGHTSGAAMWPGTD 143 Query: 276 VAINGSFPSIYMPYNGSVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVS 335 V I+ FP+ YMPYN SV FE+R++ +++W E +Y+E+PD GH GP S Sbjct: 144 VKIHKRFPTHYMPYNESVSFEDRVAKIIEW--FTSKEPINLGLLYWEDPDDMGHHLGPDS 201 Query: 336 ARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINF 395 + + +D G L++ LK+ L N +N+I+ +DHGM Q ++ + Y + ++ Sbjct: 202 PLMGPVISDIDKKLGYLIQMLKKAKLWNTLNLIITSDHGMTQCSEERLIELDQYLDKDHY 261 Query: 396 FYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVR 455 + + P I +P + +E+ L+ P + Y D+P+R HY N R Sbjct: 262 TLIDQSPVAAI----LPKE---GKFDEVYEALTHAHP--NLTVYKKEDVPERWHYKYNSR 312 Query: 456 IDKVHLFVDQQWLAVRSKSNTNCGGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENI 515 I + D+ W +++KS+ + GNHGY+N M IFLAHGP+F++ E + Sbjct: 313 IQPIIAVADEGWHILQNKSD-DFLLGNHGYDNALADMHPIFLAHGPAFRKNFSKEAMNST 371 Query: 516 EVYNLMCDLLRIQPAPNNGTHGSLNHLL 543 ++Y L+C LL I P+NG+ ++ LL Sbjct: 372 DLYPLLCHLLNITAMPHNGSFWNVQDLL 399 >gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function) [Homo sapiens] Length = 453 Score = 238 bits (606), Expect = 2e-62 Identities = 137/389 (35%), Positives = 213/389 (54%), Gaps = 22/389 (5%) Query: 159 PPVILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYP 218 P ++L S DGFRA+YL ++ P++ G+ ++++ ++ TKTFPNHY+IVTGLY Sbjct: 26 PKLLLVSFDGFRADYLKNYE--FPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYE 83 Query: 219 ESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWH-GQPMWLT-AMYQGLKAATYFWPGSEV 276 ESHGI+ N+MYD K+FS S+ +P WW+ P+W+T + + +A WPG++V Sbjct: 84 ESHGIVANSMYDAVTKKHFSDSN--DKDPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDV 141 Query: 277 AINGSFPSIYMPYNGSVPFEERISTLLKWLDLPKAERP-RFYTMYFEEPDSSGHAGGPV- 334 I+ + S +M YN SV FEER++ + WL+ + P F T+Y+EEPD+SGH GP Sbjct: 142 PIHDTISSYFMNYNSSVSFEERLNNITMWLN--NSNPPVTFATLYWEEPDASGHKYGPED 199 Query: 335 SARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRIN 394 + + L+ +D G L++ LK L +N+I+ +DHGM Q +++ + Sbjct: 200 KENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSY 259 Query: 395 FFYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNV 454 + + P I +P N E+ L P H YL D+P R +Y N Sbjct: 260 YTLIDLSPVAAI----LP----KINRTEVYNKLKNCSP--HMNVYLKEDIPNRFYYQHND 309 Query: 455 RIDKVHLFVDQQWLAVRSKSNTNCGGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFEN 514 RI + L D+ W V ++S+ G+HGY+N SM AHGP+F + + Sbjct: 310 RIQPIILVADEGWTIVLNESSQKL--GDHGYDNSLPSMHPFLAAHGPAFHKGYKHSTINI 367 Query: 515 IEVYNLMCDLLRIQPAPNNGTHGSLNHLL 543 +++Y +MC +L ++P PNNGT G LL Sbjct: 368 VDIYPMMCHILGLKPHPNNGTFGHTKCLL 396 >gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6 [Homo sapiens] Length = 440 Score = 190 bits (483), Expect = 4e-48 Identities = 122/413 (29%), Positives = 200/413 (48%), Gaps = 31/413 (7%) Query: 161 VILFSMDGFRAEYLYTWDTL--MPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYP 218 +++F +DGFR++Y+ + L +P ++ + G+ Y+ +P+ ++PN+YT++TG + Sbjct: 26 LLVFLLDGFRSDYISD-EALESLPGFKEIVSRGVKVDYLTPDFPSLSYPNYYTLMTGRHC 84 Query: 219 ESHGIIDNNMYDVNLNKNFSLS-SKEQNNPAWWHG-QPMWLTAMYQGLKAATYFWPGSEV 276 E H +I N M+D NK+F + +K+ P WW+G +P+W+T K Y+WPG EV Sbjct: 85 EVHQMIGNYMWDPTTNKSFDIGVNKDSLMPLWWNGSEPLWVTLTKAKRKVYMYYWPGCEV 144 Query: 277 AINGSFPSIYMPYNGSVPFEERISTLLK-WLDLPKAERPRFYTMYFEEPDSSGHAGGPVS 335 I G P+ + Y +VP + + + LD K+ R +Y E D GH GP S Sbjct: 145 EILGVRPTYCLEYK-NVPTDINFANAVSDALDSFKSGRADLAAIYHERIDVEGHHYGPAS 203 Query: 336 ARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINF 395 + AL+ VD + + +++R L + +N+I+ +DHGM + + + +N Sbjct: 204 PQRKDALKAVDTVLKYMTKWIQERGLQDRLNVIIFSDHGMTDIFWMDKVIELNKYISLND 263 Query: 396 FYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVR 455 + P + P EI LS +H Y +P R +Y K Sbjct: 264 LQQVKDRGPVVSLWPAPG-----KHSEIYNKLSTV---EHMTVYEKEAIPSRFYYKKGKF 315 Query: 456 IDKVHLFVDQQWLAVRSKSNT----NCGG-------GNHGYNNEFRSMEAIFLAHGPSFK 504 + + L D+ W ++ N G G HGY+NE M IFLA GP FK Sbjct: 316 VSPLTLVADEGWFITENREMLPFWMNSTGRREGWQRGWHGYDNELMDMRGIFLAFGPDFK 375 Query: 505 EKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLNHLLK-----VPFYEPSH 552 P +++VYN+MC+++ I P PNNG+ + +LK P PSH Sbjct: 376 SNFRAAPIRSVDVYNVMCNVVGITPLPNNGSWSRVMCMLKGRASTAPPVWPSH 428 >gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7 [Homo sapiens] Length = 458 Score = 187 bits (474), Expect = 5e-47 Identities = 126/398 (31%), Positives = 192/398 (48%), Gaps = 32/398 (8%) Query: 161 VILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPES 220 ++L S DGFR Y DT PN++ + G+ ++YM + T T P H+T+VTG Y E+ Sbjct: 33 LLLVSFDGFRWNYDQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIEN 90 Query: 221 HGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQ-PMWLTAMYQGLKAATYFWPGSEVAIN 279 HG++ N Y+ + W +G P+W+TA QGL+A ++F+PG V Sbjct: 91 HGVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQ 150 Query: 280 GSFPS------IYMPYNGSVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGP 333 G + I Y + I T++ W E T+YF EPDS+GH GP Sbjct: 151 GVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFT---EEDLDLVTLYFGEPDSTGHRYGP 207 Query: 334 VSARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGM--------DQTYCNKMEY 385 S + ++ VD G L E + + +L + +N+I+ +DHGM D +K Sbjct: 208 ESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFPN 267 Query: 386 MTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLP 445 T F I F + GP + +P + E++ L P H Y P Sbjct: 268 FT--FRDIEFELLDYGPNGML----LPKEG---RLEKVYDALKDAHPKLHV--YKKEAFP 316 Query: 446 KRLHYAKNVRIDKVHLFVDQQWLAVRSKSNTNCGGGNHGYNNEFRSMEAIFLAHGPSFKE 505 + HYA N R+ + ++ D ++ + + N G HG++N+ M+ IF A GPSF+ Sbjct: 317 EAFHYANNPRVTPLLMYSDLGYV-IHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRA 375 Query: 506 KTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLNHLL 543 EVEPFE++ VY LMC LL I P N+G +L +L Sbjct: 376 GLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPML 413 >gi|239755573 PREDICTED: similar to ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative function) [Homo sapiens] Length = 661 Score = 65.5 bits (158), Expect = 2e-10 Identities = 63/275 (22%), Positives = 111/275 (40%), Gaps = 51/275 (18%) Query: 316 FYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGM 375 F T+Y+ +PD+ GH P + +Q +D L+ ++ +L + +I+ DHGM Sbjct: 281 FVTLYYRQPDNVGHRFKPEAENRKLMIQQLDRTIWYLVGATEKHSLQS-PQVIITXDHGM 339 Query: 376 ----DQTYCNKMEYMTDYFPRINFFYM----YEG---PAPRIRAHNIPHDFFSFNSEEIV 424 + NK+ +++Y ++ Y G P P++ E + Sbjct: 340 MTVKKRPNVNKIX-LSNYIKFRDWVKFDIVGYGGFGLPLPKLG-----------QEEALY 387 Query: 425 RNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQWLAVRSKSNT-------- 476 + L P H Y + P+ H AK+ R+ + ++ + + + S T Sbjct: 388 QALKNAHPHLHI--YKKEEFPEHFHLAKHDRVLPIVMYANSSYRYLDSSMRTFNETRTFP 445 Query: 477 ---------------NC-GGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNL 520 C G+HG++N M+ IF GP FK+ E F +I +Y Sbjct: 446 TDQPDSLREQDARIIMCFNKGSHGFDNVLMDMKTIFRDFGPDFKKNGLAETFNSIHIYPF 505 Query: 521 MCDLLRIQPAPNNGTHGSLNHLLKVPFYEPSHAEE 555 +C LL + P +NG+ +L V Y+ A E Sbjct: 506 VCKLLGVXPQTHNGSLAVTQEML-VNSYDQQPASE 539 Score = 52.0 bits (123), Expect = 2e-06 Identities = 37/123 (30%), Positives = 58/123 (47%), Gaps = 12/123 (9%) Query: 152 CPEGFDLPP-------VILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTK 204 CP G PP ++L S GFR + DT PN++ L G+ +KY+ T Sbjct: 13 CPAGRPPPPREEEHSQLLLISFQGFRWDXDQDVDT--PNMDHLAGEGVKAKYLMPPLVTM 70 Query: 205 TFPNHYTIVTG--LYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHG-QPMWLTAMY 261 T P H+T + G L+ H +I N M++ + N S + ++ + +W+TA Sbjct: 71 TSPFHFTAMPGKLLWVRDHXVIHNMMFNTEMLWNCSFKTTQKKTQCXDNRVLSLWITAQR 130 Query: 262 QGL 264 QGL Sbjct: 131 QGL 133 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 52.4 bits (124), Expect = 2e-06 Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 14/115 (12%) Query: 19 KKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFDASFRGLENCRCDVACKDR 78 K I ++LL++ VI + + SC +C + R C CD C+ Sbjct: 4 KTLPIYLLLLLSVFVIQQVSS---------QDLSSCAGRCGEGYSRDA-TCNCDYNCQHY 53 Query: 79 GDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCLQRKDCCADYKSVC 133 +CC DF+ C + K RC E+ C C C + CC DY+S C Sbjct: 54 MECCPDFKRVCTAE----LSCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFC 104 Score = 43.1 bits (100), Expect = 0.001 Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 1/39 (2%) Query: 53 SCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVE 91 SC+ +CF++ RG E C CD CK CC D+E C E Sbjct: 69 SCKGRCFESFERGRE-CDCDAQCKKYDKCCPDYESFCAE 106 Score = 39.3 bits (90), Expect = 0.016 Identities = 15/37 (40%), Positives = 20/37 (54%) Query: 102 RCGETRLEASLCSCSDDCLQRKDCCADYKSVCQGETS 138 RCGE + C+C +C +CC D+K VC E S Sbjct: 33 RCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAELS 69 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 52.4 bits (124), Expect = 2e-06 Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 14/115 (12%) Query: 19 KKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFDASFRGLENCRCDVACKDR 78 K I ++LL++ VI + + SC +C + R C CD C+ Sbjct: 4 KTLPIYLLLLLSVFVIQQVSS---------QDLSSCAGRCGEGYSRDA-TCNCDYNCQHY 53 Query: 79 GDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCLQRKDCCADYKSVC 133 +CC DF+ C + K RC E+ C C C + CC DY+S C Sbjct: 54 MECCPDFKRVCTAE----LSCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFC 104 Score = 43.1 bits (100), Expect = 0.001 Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 1/39 (2%) Query: 53 SCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVE 91 SC+ +CF++ RG E C CD CK CC D+E C E Sbjct: 69 SCKGRCFESFERGRE-CDCDAQCKKYDKCCPDYESFCAE 106 Score = 39.3 bits (90), Expect = 0.016 Identities = 15/37 (40%), Positives = 20/37 (54%) Query: 102 RCGETRLEASLCSCSDDCLQRKDCCADYKSVCQGETS 138 RCGE + C+C +C +CC D+K VC E S Sbjct: 33 RCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAELS 69 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 44.3 bits (103), Expect = 5e-04 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 11/73 (15%) Query: 19 KKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFDASFRGLENCRCDVACKDR 78 K I ++LL++ VI + ++ SC+ +CF++ RG E C CD CK Sbjct: 4 KTLPIYLLLLLSVFVIQQVS----------SQELSCKGRCFESFERGRE-CDCDAQCKKY 52 Query: 79 GDCCWDFEDTCVE 91 CC D+E C E Sbjct: 53 DKCCPDYESFCAE 65 Score = 32.3 bits (72), Expect = 2.0 Identities = 13/34 (38%), Positives = 16/34 (47%) Query: 100 KFRCGETRLEASLCSCSDDCLQRKDCCADYKSVC 133 K RC E+ C C C + CC DY+S C Sbjct: 30 KGRCFESFERGRECDCDAQCKKYDKCCPDYESFC 63 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 44.3 bits (103), Expect = 5e-04 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 11/73 (15%) Query: 19 KKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFDASFRGLENCRCDVACKDR 78 K I ++LL++ VI + ++ SC+ +CF++ RG E C CD CK Sbjct: 4 KTLPIYLLLLLSVFVIQQVS----------SQELSCKGRCFESFERGRE-CDCDAQCKKY 52 Query: 79 GDCCWDFEDTCVE 91 CC D+E C E Sbjct: 53 DKCCPDYESFCAE 65 Score = 32.3 bits (72), Expect = 2.0 Identities = 13/34 (38%), Positives = 16/34 (47%) Query: 100 KFRCGETRLEASLCSCSDDCLQRKDCCADYKSVC 133 K RC E+ C C C + CC DY+S C Sbjct: 30 KGRCFESFERGRECDCDAQCKKYDKCCPDYESFC 63 >gi|169217819 PREDICTED: similar to hCG1793095 [Homo sapiens] Length = 167 Score = 43.9 bits (102), Expect = 7e-04 Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 2/57 (3%) Query: 161 VILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLY 217 ++L S D FR Y DT PN++ + G+ ++YM + T T P H+T+VTG Y Sbjct: 33 LLLVSFDSFRWNYEQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGEY 87 >gi|239756564 PREDICTED: similar to hCG1793095 [Homo sapiens] Length = 98 Score = 43.9 bits (102), Expect = 7e-04 Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 2/57 (3%) Query: 161 VILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLY 217 ++L S D FR Y DT PN++ + G+ ++YM + T T P H+T+VTG Y Sbjct: 33 LLLVSFDSFRWNYEQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGEY 87 >gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens] Length = 476 Score = 42.4 bits (98), Expect = 0.002 Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 15/66 (22%) Query: 75 CKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDC-LQRKDCCADYKSVC 133 C++ G CC D +D CV T + N +LC C C + DCC DYKS C Sbjct: 57 CRNFG-CCEDRDDGCV--TEFYAAN-----------ALCYCDKFCDRENSDCCPDYKSFC 102 Query: 134 QGETSW 139 + E W Sbjct: 103 REEKEW 108 >gi|5174623 placental protein 11 precursor [Homo sapiens] Length = 369 Score = 40.4 bits (93), Expect = 0.007 Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%) Query: 53 SCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTC 89 SC+ +C++A F C C+ C++ G+CC DFE C Sbjct: 48 SCQGRCYEA-FDKHHQCHCNARCQEFGNCCKDFESLC 83 >gi|224451073 endo/exonuclease (5'-3'), endonuclease G-like isoform 1 precursor [Homo sapiens] Length = 368 Score = 39.3 bits (90), Expect = 0.016 Identities = 54/250 (21%), Positives = 106/250 (42%), Gaps = 38/250 (15%) Query: 627 HREYVSGFGKAMRMPMWSSYTVPQ---LGDTSPLPPTVPDC-LRADVRVPPSESQKCSFY 682 + + + +A R+P W + + +GD C + D +PP+ S Y Sbjct: 77 YTNHALSYDQAKRVPRWVLEHISKSKIMGDADR-----KHCKFKPDPNIPPTFSAFNEDY 131 Query: 683 LADKNITHGFLYPPASNR-TSDSQYDALITSNLVPMYEEFRKMWDYFHSV-LLIKHATER 740 + + G + P +N+ +S + + SN+VP ++F Y++ + + + TER Sbjct: 132 VGS-GWSRGHMAPAGNNKFSSKAMAETFYLSNIVP--QDFDNNSGYWNRIEMYCRELTER 188 Query: 741 -NGVNVVSGPIFDYNYDGHFDAPDEITKHLANTD-VPIPTHYFVVLTSCKNKSHTPENCP 798 V VVSGP+ G D ++ + D V +P+H + V+ + ++ T Sbjct: 189 FEDVWVVSGPLTLPQTRG--DGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLAL 246 Query: 799 GWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRDVELLTGLDFYQ--DKVQ 856 G F++P+ EA+ + + T ++D+E L+GL F+ D+ Sbjct: 247 G-----AFVVPN-------------EAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTS 288 Query: 857 PVSEILQLKT 866 + I + T Sbjct: 289 DIRNICSVDT 298 >gi|224451075 endo/exonuclease (5'-3'), endonuclease G-like isoform 2 precursor [Homo sapiens] Length = 318 Score = 38.5 bits (88), Expect = 0.027 Identities = 47/207 (22%), Positives = 91/207 (43%), Gaps = 29/207 (14%) Query: 666 RADVRVPPSESQKCSFYLADKNITHGFLYPPASNR-TSDSQYDALITSNLVPMYEEFRKM 724 + D +PP+ S Y+ + G + P +N+ +S + + SN+VP ++F Sbjct: 65 KPDPNIPPTFSAFNEDYVGS-GWSRGHMAPAGNNKFSSKAMAETFYLSNIVP--QDFDNN 121 Query: 725 WDYFHSV-LLIKHATER-NGVNVVSGPIFDYNYDGHFDAPDEITKHLANTD-VPIPTHYF 781 Y++ + + + TER V VVSGP+ G D ++ + D V +P+H + Sbjct: 122 SGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRG--DGKKIVSYQVIGEDNVAVPSHLY 179 Query: 782 VVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRD 841 V+ + ++ T G F++P+ EA+ + + T ++D Sbjct: 180 KVILARRSSVSTEPLALG-----AFVVPN-------------EAIGFQPQLTEFQVSLQD 221 Query: 842 VELLTGLDFYQ--DKVQPVSEILQLKT 866 +E L+GL F+ D+ + I + T Sbjct: 222 LEKLSGLVFFPHLDRTSDIRNICSVDT 248 >gi|169209673 PREDICTED: similar to hCG2042391 [Homo sapiens] Length = 129 Score = 38.1 bits (87), Expect = 0.036 Identities = 26/108 (24%), Positives = 45/108 (41%), Gaps = 9/108 (8%) Query: 262 QGLKAATYFWPGSEVAINGS------FPSIYMPYNGSVPFEERISTLLKWLDLPKAERPR 315 QG KAA+ + +G S P + + E I T++ W + Sbjct: 14 QGNKAASSHYSRGGAKYDGEAVKRSLVESYTHPNSNETEWRENIDTVMNWFTKEDFD--- 70 Query: 316 FYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHN 363 F T+ + EPD+ GH GP + +Q +D G L+ ++ +L + Sbjct: 71 FVTLCYREPDNVGHRFGPEAENRKLMIQQIDRTIGYLVGATEKHSLQS 118 >gi|169210658 PREDICTED: similar to hCG2042391 [Homo sapiens] Length = 129 Score = 38.1 bits (87), Expect = 0.036 Identities = 26/108 (24%), Positives = 45/108 (41%), Gaps = 9/108 (8%) Query: 262 QGLKAATYFWPGSEVAINGS------FPSIYMPYNGSVPFEERISTLLKWLDLPKAERPR 315 QG KAA+ + +G S P + + E I T++ W + Sbjct: 14 QGNKAASSHYSRGGAKYDGEAVKRSLVESYTHPNSNETEWRENIDTVMNWFTKEDFD--- 70 Query: 316 FYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHN 363 F T+ + EPD+ GH GP + +Q +D G L+ ++ +L + Sbjct: 71 FVTLCYREPDNVGHRFGPEAENRKLMIQQIDRTIGYLVGATEKHSLQS 118 >gi|169210188 PREDICTED: similar to hCG2042391 [Homo sapiens] Length = 129 Score = 38.1 bits (87), Expect = 0.036 Identities = 26/108 (24%), Positives = 45/108 (41%), Gaps = 9/108 (8%) Query: 262 QGLKAATYFWPGSEVAINGS------FPSIYMPYNGSVPFEERISTLLKWLDLPKAERPR 315 QG KAA+ + +G S P + + E I T++ W + Sbjct: 14 QGNKAASSHYSRGGAKYDGEAVKRSLVESYTHPNSNETEWRENIDTVMNWFTKEDFD--- 70 Query: 316 FYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHN 363 F T+ + EPD+ GH GP + +Q +D G L+ ++ +L + Sbjct: 71 FVTLCYREPDNVGHRFGPEAENRKLMIQQIDRTIGYLVGATEKHSLQS 118 >gi|239743493 PREDICTED: hypothetical protein XP_002342862 [Homo sapiens] Length = 169 Score = 37.4 bits (85), Expect = 0.061 Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 3/76 (3%) Query: 288 PYNGSVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDH 347 P + +E I T++ W + F T+ + EPD+ GH GP + + +Q +D Sbjct: 86 PSSNETERKENIDTVMNWFTKEDFD---FVTLCYREPDNVGHRFGPEAEKRKLMIQQIDR 142 Query: 348 AFGMLMEGLKQRNLHN 363 G L+ ++ +L + Sbjct: 143 TIGYLVGATEKHSLQS 158 >gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] Length = 3874 Score = 37.0 bits (84), Expect = 0.080 Identities = 31/119 (26%), Positives = 45/119 (37%), Gaps = 28/119 (23%) Query: 54 CRKKCFDASFRGLENCRC---------DVACKDRGDCCWDFEDTCVESTR-IWMCNKFRC 103 C C +A G +C C D C+D +C WD C E R + + +RC Sbjct: 3454 CSHACLNAP--GRFSCTCPTGFALAWDDRNCRDVDECAWD-AHLCREGQRCVNLLGSYRC 3510 Query: 104 ------GETRLEASLCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGF 156 G + + C D+CL+ D C Y +C EN + CP G+ Sbjct: 3511 LPDCGPGFRVADGAGCEDVDECLEGLDDC-HYNQLC--------ENTPGGHRCSCPRGY 3560 >gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] Length = 5065 Score = 37.0 bits (84), Expect = 0.080 Identities = 31/119 (26%), Positives = 45/119 (37%), Gaps = 28/119 (23%) Query: 54 CRKKCFDASFRGLENCRC---------DVACKDRGDCCWDFEDTCVESTR-IWMCNKFRC 103 C C +A G +C C D C+D +C WD C E R + + +RC Sbjct: 4645 CSHACLNAP--GRFSCTCPTGFALAWDDRNCRDVDECAWD-AHLCREGQRCVNLLGSYRC 4701 Query: 104 ------GETRLEASLCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGF 156 G + + C D+CL+ D C Y +C EN + CP G+ Sbjct: 4702 LPDCGPGFRVADGAGCEDVDECLEGLDDC-HYNQLC--------ENTPGGHRCSCPRGY 4751 >gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] Length = 3783 Score = 37.0 bits (84), Expect = 0.080 Identities = 31/119 (26%), Positives = 45/119 (37%), Gaps = 28/119 (23%) Query: 54 CRKKCFDASFRGLENCRC---------DVACKDRGDCCWDFEDTCVESTR-IWMCNKFRC 103 C C +A G +C C D C+D +C WD C E R + + +RC Sbjct: 3363 CSHACLNAP--GRFSCTCPTGFALAWDDRNCRDVDECAWD-AHLCREGQRCVNLLGSYRC 3419 Query: 104 ------GETRLEASLCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGF 156 G + + C D+CL+ D C Y +C EN + CP G+ Sbjct: 3420 LPDCGPGFRVADGAGCEDVDECLEGLDDC-HYNQLC--------ENTPGGHRCSCPRGY 3469 >gi|10092665 sushi domain containing 2 [Homo sapiens] Length = 822 Score = 37.0 bits (84), Expect = 0.080 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 5/60 (8%) Query: 32 LVIMSLGLGLGLGLRKLEKQGSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVE 91 L++++ LG G G + Q SC +C + G C C C G CC DF D C+E Sbjct: 10 LLLLATALGPGPG-PTADAQESCSMRC--GALDG--PCSCHPTCSGLGTCCLDFRDFCLE 64 >gi|187608446 phosphatidylinositol glycan anchor biosynthesis, class G isoform 1 [Homo sapiens] Length = 983 Score = 35.4 bits (80), Expect = 0.23 Identities = 52/237 (21%), Positives = 87/237 (36%), Gaps = 38/237 (16%) Query: 158 LPP-----VILFSMDGFRAEYLYTWDTL--MPNINKLKTCGI-HSKYMRAMYPTKTFPNH 209 LPP V++ +D R ++++ + MP L G HS A PT T P Sbjct: 60 LPPPLFSKVVIVLIDALRDDFVFGSKGVKFMPYTTYLVEKGASHSFVAEAKPPTVTMPRI 119 Query: 210 YTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATY 269 ++TG P +I N L + +K ++G W+ Sbjct: 120 KALMTGSLPGFVDVIRNLNSPALLEDSVIRQAKAAGKRIVFYGDETWVKL---------- 169 Query: 270 FWPGSEVAINGSFPSIYMPYNGSVPF-----EERISTLLKWLD-LPKAERPRFYTMYFEE 323 FP ++ Y+G+ F E + + + LD + K +++ Sbjct: 170 ------------FPKHFVEYDGTTSFFVSDYTEVDNNVTRHLDKVLKRGDWDILILHYLG 217 Query: 324 PDSSGHAGGPVSARVIKALQVVDHAFGMLMEGL--KQRNLHNCVNIILLADHGMDQT 378 D GH GP S + + L +D + L K+R ++L DHGM +T Sbjct: 218 LDHIGHISGPNSPLIGQKLSEMDSVLMKIHTSLQSKERETPLPNLLVLCGDHGMSET 274 >gi|187608438 phosphatidylinositol glycan anchor biosynthesis, class G isoform 2 [Homo sapiens] Length = 975 Score = 35.4 bits (80), Expect = 0.23 Identities = 52/237 (21%), Positives = 87/237 (36%), Gaps = 38/237 (16%) Query: 158 LPP-----VILFSMDGFRAEYLYTWDTL--MPNINKLKTCGI-HSKYMRAMYPTKTFPNH 209 LPP V++ +D R ++++ + MP L G HS A PT T P Sbjct: 60 LPPPLFSKVVIVLIDALRDDFVFGSKGVKFMPYTTYLVEKGASHSFVAEAKPPTVTMPRI 119 Query: 210 YTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATY 269 ++TG P +I N L + +K ++G W+ Sbjct: 120 KALMTGSLPGFVDVIRNLNSPALLEDSVIRQAKAAGKRIVFYGDETWVKL---------- 169 Query: 270 FWPGSEVAINGSFPSIYMPYNGSVPF-----EERISTLLKWLD-LPKAERPRFYTMYFEE 323 FP ++ Y+G+ F E + + + LD + K +++ Sbjct: 170 ------------FPKHFVEYDGTTSFFVSDYTEVDNNVTRHLDKVLKRGDWDILILHYLG 217 Query: 324 PDSSGHAGGPVSARVIKALQVVDHAFGMLMEGL--KQRNLHNCVNIILLADHGMDQT 378 D GH GP S + + L +D + L K+R ++L DHGM +T Sbjct: 218 LDHIGHISGPNSPLIGQKLSEMDSVLMKIHTSLQSKERETPLPNLLVLCGDHGMSET 274 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.137 0.440 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,970,808 Number of Sequences: 37866 Number of extensions: 1802181 Number of successful extensions: 3857 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 26 Number of HSP's successfully gapped in prelim test: 26 Number of HSP's that attempted gapping in prelim test: 3745 Number of HSP's gapped (non-prelim): 89 length of query: 875 length of database: 18,247,518 effective HSP length: 111 effective length of query: 764 effective length of database: 14,044,392 effective search space: 10729915488 effective search space used: 10729915488 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.