Search of human proteins with 110835708

Search of human proteins with 110835708

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110835708 solute carrier family 5 (inositol transporters),
member 3 [Homo sapiens]
         (718 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110835708 solute carrier family 5 (inositol transporters), me...  1427   0.0  
gi|17941285 solute carrier family 5 (sodium/glucose cotransporte...   636   0.0  
gi|206597483 solute carrier family 5 (sodium/glucose cotransport...   624   e-179
gi|4507031 solute carrier family 5 (sodium/glucose cotransporter...   624   e-178
gi|206597487 solute carrier family 5 (sodium/glucose cotransport...   610   e-174
gi|4507033 solute carrier family 5 (sodium/glucose cotransporter...   608   e-174
gi|109659836 solute carrier family 5 (sodium/glucose cotransport...   595   e-170
gi|109659839 solute carrier family 5 (sodium/glucose cotransport...   587   e-167
gi|14140236 solute carrier family 5 (low affinity glucose cotran...   572   e-163
gi|157671931 solute carrier family 5 (sodium/glucose cotransport...   111   2e-24
gi|4507035 solute carrier family 5 (sodium iodide symporter), me...   102   1e-21
gi|167466278 solute carrier family 5 (iodide transporter), membe...    94   6e-19
gi|10863879 solute carrier family 5 (sodium-dependent vitamin tr...    89   1e-17
gi|11141885 solute carrier family 5 (choline transporter), membe...    81   3e-15
gi|21361581 solute carrier family 6 (neurotransmitter transporte...    43   0.001
gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]         37   0.064
gi|188528618 solute carrier family 6 (neurotransmitter transport...    36   0.11 
gi|197276623 solute carrier family 6 (neurotransmitter transport...    33   0.92 
gi|54607094 solute carrier family 6 (neurotransmitter transporte...    33   0.92 
gi|7657587 solute carrier family 6 (neurotransmitter transporter...    32   2.1  
gi|197333868 T-box 2 [Homo sapiens]                                    32   2.1  
gi|156139155 guanine nucleotide binding protein, alpha transduci...    32   2.7  
gi|193083148 cytochrome P450 family 2 subfamily C polypeptide 18...    32   2.7  
gi|13699816 cytochrome P450 family 2 subfamily C polypeptide 18 ...    32   2.7  
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]      31   3.5  
gi|40789261 solute carrier family 16, member 6 [Homo sapiens]          31   4.6  
gi|61966919 hypothetical protein LOC442444 [Homo sapiens]              30   6.0  
gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]                   30   7.8  

>gi|110835708 solute carrier family 5 (inositol transporters),
           member 3 [Homo sapiens]
          Length = 718

 Score = 1427 bits (3694), Expect = 0.0
 Identities = 718/718 (100%), Positives = 718/718 (100%)

Query: 1   MRAVLDTADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNI 60
           MRAVLDTADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNI
Sbjct: 1   MRAVLDTADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNI 60

Query: 61  GSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGH 120
           GSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGH
Sbjct: 61  GSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGH 120

Query: 121 RIQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVA 180
           RIQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVA
Sbjct: 121 RIQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVA 180

Query: 181 VIYTDTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCN 240
           VIYTDTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCN
Sbjct: 181 VIYTDTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCN 240

Query: 241 VSPKKEALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTL 300
           VSPKKEALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTL
Sbjct: 241 VSPKKEALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTL 300

Query: 301 MAGFLKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVP 360
           MAGFLKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVP
Sbjct: 301 MAGFLKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVP 360

Query: 361 VGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVV 420
           VGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVV
Sbjct: 361 VGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVV 420

Query: 421 ISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVL 480
           ISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVL
Sbjct: 421 ISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVL 480

Query: 481 GAVRLILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVIVSLLTPPPTKEQ 540
           GAVRLILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVIVSLLTPPPTKEQ
Sbjct: 481 GAVRLILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVIVSLLTPPPTKEQ 540

Query: 541 IRTTTFWSKKNLVVKENCSPKEEPYQMQEKSILRCSENNETINHIIPNGKSEDSIKGLQP 600
           IRTTTFWSKKNLVVKENCSPKEEPYQMQEKSILRCSENNETINHIIPNGKSEDSIKGLQP
Sbjct: 541 IRTTTFWSKKNLVVKENCSPKEEPYQMQEKSILRCSENNETINHIIPNGKSEDSIKGLQP 600

Query: 601 EDVNLLVTCREEGNPVASLGHSEAETPVDAYSNGQAALMGEKERKKETDDGGRYWKFIDW 660
           EDVNLLVTCREEGNPVASLGHSEAETPVDAYSNGQAALMGEKERKKETDDGGRYWKFIDW
Sbjct: 601 EDVNLLVTCREEGNPVASLGHSEAETPVDAYSNGQAALMGEKERKKETDDGGRYWKFIDW 660

Query: 661 FCGFKSKSLSKRSLRDLMEEEAVCLQMLEETRQVKVILNIGLFAVCSLGIFMFVYFSL 718
           FCGFKSKSLSKRSLRDLMEEEAVCLQMLEETRQVKVILNIGLFAVCSLGIFMFVYFSL
Sbjct: 661 FCGFKSKSLSKRSLRDLMEEEAVCLQMLEETRQVKVILNIGLFAVCSLGIFMFVYFSL 718


>gi|17941285 solute carrier family 5 (sodium/glucose cotransporter),
           member 11 [Homo sapiens]
          Length = 675

 Score =  636 bits (1641), Expect = 0.0
 Identities = 333/714 (46%), Positives = 456/714 (63%), Gaps = 63/714 (8%)

Query: 5   LDTADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNIGSEH 64
           L+  DIA++ LYF+ V+ +G ++  K+ R TV GYFLAG  M W  +GASLF SN+GS H
Sbjct: 24  LEPGDIAVLVLYFLFVLAVGLWSTVKTKRDTVKGYFLAGGDMVWWPVGASLFASNVGSGH 83

Query: 65  FIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQV 124
           FIGLAGSGAA+G +V A+E N L  + +L W+F+PIYI   V TMPEYL KRFGG RI +
Sbjct: 84  FIGLAGSGAATGISVSAYELNGLFSVLMLAWIFLPIYIAGQVTTMPEYLRKRFGGIRIPI 143

Query: 125 YFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYT 184
             A L L +YIFTK+SVD+Y+GA+FIQ+SL  +LY++++ L+ +TA+ TV GGL AVIYT
Sbjct: 144 ILAVLYLFIYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITAVYTVAGGLAAVIYT 203

Query: 185 DTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSPK 244
           D LQ L+M+IGALTLM  S   +GG E +K +Y LA        L  N S  +SC + P+
Sbjct: 204 DALQTLIMLIGALTLMGYSFAAVGGMEGLKEKYFLA--------LASNRSENSSCGL-PR 254

Query: 245 KEALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGF 304
           ++A  + R+P   D+PWPG + G +  S+WYWC DQVIVQR LAAKN++HAKG  LMA +
Sbjct: 255 EDAFHIFRDPLTSDLPWPGVLFGMSIPSLWYWCTDQVIVQRTLAAKNLSHAKGGALMAAY 314

Query: 305 LKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVPVGLR 364
           LK+LP+FI+V PGM+SRILF D +AC +PE C  +C + +GCS+IAYP+LV++L+P GLR
Sbjct: 315 LKVLPLFIMVFPGMVSRILFPDQVACADPEICQKICSNPSGCSDIAYPKLVLELLPTGLR 374

Query: 365 GLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISIA 424
           GLMMAVM+AALMS L SIFNSASTIFT+D++  +R  AS +ELMIVGR+FV  +V++SI 
Sbjct: 375 GLMMAVMVAALMSSLTSIFNSASTIFTMDLWNHLRPRASEKELMIVGRVFVLLLVLVSIL 434

Query: 425 WVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAVR 484
           W+P++   QGGQ+++YIQ ++ YL PPVA +F++  FWKR NE+GAF+G ++G +LG VR
Sbjct: 435 WIPVVQASQGGQLFIYIQSISSYLQPPVAVVFIMGCFWKRTNEKGAFWGLISGLLLGLVR 494

Query: 485 LILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVIVSLLTPPPTKEQIRTT 544
           L+L F Y  P CDQPD RP  +K IHY+Y +  L  VT +    VS  T PP+KE +   
Sbjct: 495 LVLDFIYVQPRCDQPDERPVLVKSIHYLYFSMILSTVTLITVSTVSWFTEPPSKEMVSHL 554

Query: 545 TFWSKKNLVVKENCSPKEEPYQMQEKSILRCSENNETINHIIPNGKSEDSIKGLQPEDVN 604
           T++++ + VV++  +P   P                                        
Sbjct: 555 TWFTRHDPVVQKEQAPPAAP---------------------------------------- 574

Query: 605 LLVTCREEGNPVASLGHS-EAETPVDAYSNGQAALMGEKERKKETDDGGRYWKFIDWFCG 663
           L +T  + G P AS   S + E   +  S   +  M  K+ K          K I W CG
Sbjct: 575 LSLTLSQNGMPEASSSSSVQFEMVQENTSKTHSCDMTPKQSK--------VVKAILWLCG 626

Query: 664 FKSKSLSKRSLRDLMEEEAVCLQMLEETRQVKVILNIGLFAVCSLGIFMFVYFS 717
            + K   +   R     EA+ +  LEE   VK +L++ L    S  IF++ YF+
Sbjct: 627 IQEKGKEELPAR----AEAIIVS-LEENPLVKTLLDVNLIFCVSCAIFIWGYFA 675


>gi|206597483 solute carrier family 5 (sodium/glucose
           cotransporter), member 9 isoform 2 [Homo sapiens]
          Length = 681

 Score =  624 bits (1610), Expect = e-179
 Identities = 333/719 (46%), Positives = 462/719 (64%), Gaps = 70/719 (9%)

Query: 2   RAVLDTADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNIG 61
           R  L   DI++V +YF+ V+ +G ++  +++R T+ GYFLAGRSM+W  IGASL  SN+G
Sbjct: 30  RVGLHAYDISVVVIYFVFVIAVGIWSSIRASRGTIGGYFLAGRSMSWWPIGASLMSSNVG 89

Query: 62  SEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHR 121
           S  FIGLAG+GAA G AVG +E+NA  LL  LGWVF+P+YI +GV TMP+YL KRFGG R
Sbjct: 90  SGLFIGLAGTGAAGGLAVGGFEWNATWLLLALGWVFVPVYIAAGVVTMPQYLKKRFGGQR 149

Query: 122 IQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAV 181
           IQVY + LSLILYIFTK+S D++SGALFIQ +LGWNLY+S  +L+ +TA+ T+ GGL+AV
Sbjct: 150 IQVYMSVLSLILYIFTKISTDIFSGALFIQMALGWNLYLSTGILLVVTAVYTIAGGLMAV 209

Query: 182 IYTDTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNV 241
           IYTD LQ ++M+ GAL LM +   ++G +  +++RY  A P+VT       + NT +C++
Sbjct: 210 IYTDALQTVIMVGGALVLMFLGFQDVGWYPGLEQRYRQAIPNVT-------VPNT-TCHL 261

Query: 242 SPKKEALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLM 301
            P+ +A  +LR+P   D+PWPG I G T  + W WC DQVIVQR L+AK+++HAKG +++
Sbjct: 262 -PRPDAFHILRDPVSGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLSAKSLSHAKGGSVL 320

Query: 302 AGFLKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVPV 361
            G+LK+LPMF IV+PGMISR LF D++ C++P+ C  +CG+R GCSNIAYP+LVM L+PV
Sbjct: 321 GGYLKILPMFFIVMPGMISRALFPDEVGCVDPDVCQRICGARVGCSNIAYPKLVMALMPV 380

Query: 362 GLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVI 421
           GLRGLM+AV++AALMS L SIFNS+ST+FT+DV++  R+ ++ +ELM+VGR+FV F+VVI
Sbjct: 381 GLRGLMIAVIMAALMSSLTSIFNSSSTLFTIDVWQRFRRKSTEQELMVVGRVFVVFLVVI 440

Query: 422 SIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLG 481
           SI W+PII     GQ++ YIQ V  YL PP+ ALFLLAIF KR  E GAF+G + G  +G
Sbjct: 441 SILWIPIIQSSNSGQLFDYIQAVTSYLAPPITALFLLAIFCKRVTEPGAFWGLVFGLGVG 500

Query: 482 AVRLILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVIVSLLTPPPTKEQI 541
            +R+IL F+Y AP C + D RP  +KD HY+Y A  L  +T ++ VIVSL T P  +EQ+
Sbjct: 501 LLRMILEFSYPAPACGEVDRRPAVLKDFHYLYFAILLCGLTAIVIVIVSLCTTPIPEEQL 560

Query: 542 RTTTFWSKKNLVVKENCSPKEEPYQMQEKSILRCSENNETINHIIPNGKSEDSIKGLQPE 601
              T+W++       NC     P    EK      E +E+   I      E    G   E
Sbjct: 561 TRLTWWTR-------NC-----PLSELEK------EAHESTPEISERPAGECPAGGGAAE 602

Query: 602 DVNLLVTCREEGNPVASLGHSEAETPVDAYSNGQAALMGEKERKKETDDGGRYWKFIDWF 661
           +              +SLG  + E P  ++                   G   W    WF
Sbjct: 603 N--------------SSLGQEQPEAPSRSW-------------------GKLLW---SWF 626

Query: 662 CGFK---SKSLSKRSLRDLMEEEAVCLQMLEETRQVKVILNIGLFAVCSLGIFMFVYFS 717
           CG      ++LS      L ++    L  +EE    + + NI    + ++ IF++ YF+
Sbjct: 627 CGLSGTPEQALSPAEKAALEQK----LTSIEEEPLWRHVCNINAVLLLAINIFLWGYFA 681


>gi|4507031 solute carrier family 5 (sodium/glucose cotransporter),
           member 1 [Homo sapiens]
          Length = 664

 Score =  624 bits (1608), Expect = e-178
 Identities = 293/532 (55%), Positives = 402/532 (75%), Gaps = 4/532 (0%)

Query: 4   VLDTADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNIGSE 63
           + + ADI+I+ +YF++VM +G +AM+ +NR TV G+FLAGRSM W  IGASLF SNIGS 
Sbjct: 23  IRNAADISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSG 82

Query: 64  HFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQ 123
           HF+GLAG+GAASG A+G +E+NAL+L+ +LGW+F+PIYI++GV TMPEYL KRFGG RIQ
Sbjct: 83  HFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQ 142

Query: 124 VYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIY 183
           VY + LSL+LYIFTK+S D++SGA+FI  +LG NLY+++ LL+ +TAL T+TGGL AVIY
Sbjct: 143 VYLSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIY 202

Query: 184 TDTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSP 243
           TDTLQ ++M++G+L L   +  E+GG++    +YM A P + S     N +    C  +P
Sbjct: 203 TDTLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVS---DGNTTFQEKC-YTP 258

Query: 244 KKEALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAG 303
           + ++  + R+P   D+PWPGFI G +  ++WYWC DQVIVQR L+AKN++H KG  ++ G
Sbjct: 259 RADSFHIFRDPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQRCLSAKNMSHVKGGCILCG 318

Query: 304 FLKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVPVGL 363
           +LKL+PMFI+V+PGMISRIL+T+ IAC+ P  C   CG++ GC+NIAYP LV++L+P GL
Sbjct: 319 YLKLMPMFIMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPNGL 378

Query: 364 RGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISI 423
           RGLM++VM+A+LMS L SIFNSAST+FT+D+Y  +RK AS +ELMI GR+F+  ++ ISI
Sbjct: 379 RGLMLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISI 438

Query: 424 AWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAV 483
           AWVPI+   Q GQ++ YIQ +  YL PP+AA+FLLAIFWKR NE GAF+G + G ++G  
Sbjct: 439 AWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLIGIS 498

Query: 484 RLILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVIVSLLTPP 535
           R+I  FAY    C +P N P  I  +HY+Y A  LF ++ +  V++SLLT P
Sbjct: 499 RMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFAISFITIVVISLLTKP 550


>gi|206597487 solute carrier family 5 (sodium/glucose
           cotransporter), member 9 isoform 1 [Homo sapiens]
          Length = 706

 Score =  610 bits (1574), Expect = e-174
 Identities = 333/744 (44%), Positives = 462/744 (62%), Gaps = 95/744 (12%)

Query: 2   RAVLDTADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNIG 61
           R  L   DI++V +YF+ V+ +G ++  +++R T+ GYFLAGRSM+W  IGASL  SN+G
Sbjct: 30  RVGLHAYDISVVVIYFVFVIAVGIWSSIRASRGTIGGYFLAGRSMSWWPIGASLMSSNVG 89

Query: 62  SEHFIGLAGSGAASGFAVGAWEFN-------------------------ALLLLQLLGWV 96
           S  FIGLAG+GAA G AVG +E+N                         A  LL  LGWV
Sbjct: 90  SGLFIGLAGTGAAGGLAVGGFEWNMRKSRSGGDRGIHPRSHGRTGVRSQATWLLLALGWV 149

Query: 97  FIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSLILYIFTKLSVDLYSGALFIQESLGW 156
           F+P+YI +GV TMP+YL KRFGG RIQVY + LSLILYIFTK+S D++SGALFIQ +LGW
Sbjct: 150 FVPVYIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGALFIQMALGW 209

Query: 157 NLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGALTLMIISIMEIGGFEEVKRR 216
           NLY+S  +L+ +TA+ T+ GGL+AVIYTD LQ ++M+ GAL LM +   ++G +  +++R
Sbjct: 210 NLYLSTGILLVVTAVYTIAGGLMAVIYTDALQTVIMVGGALVLMFLGFQDVGWYPGLEQR 269

Query: 217 YMLASPDVTSILLTYNLSNTNSCNVSPKKEALKMLRNPTDEDVPWPGFILGQTPASVWYW 276
           Y  A P+VT       + NT +C++ P+ +A  +LR+P   D+PWPG I G T  + W W
Sbjct: 270 YRQAIPNVT-------VPNT-TCHL-PRPDAFHILRDPVSGDIPWPGLIFGLTVLATWCW 320

Query: 277 CADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLPMFIIVVPGMISRILFTDDIACINPEHC 336
           C DQVIVQR L+AK+++HAKG +++ G+LK+LPMF IV+PGMISR LF D++ C++P+ C
Sbjct: 321 CTDQVIVQRSLSAKSLSHAKGGSVLGGYLKILPMFFIVMPGMISRALFPDEVGCVDPDVC 380

Query: 337 MLVCGSRAGCSNIAYPRLVMKLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYK 396
             +CG+R GCSNIAYP+LVM L+PVGLRGLM+AV++AALMS L SIFNS+ST+FT+DV++
Sbjct: 381 QRICGARVGCSNIAYPKLVMALMPVGLRGLMIAVIMAALMSSLTSIFNSSSTLFTIDVWQ 440

Query: 397 LIRKSASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALF 456
             R+ ++ +ELM+VGR+FV F+VVISI W+PII     GQ++ YIQ V  YL PP+ ALF
Sbjct: 441 RFRRKSTEQELMVVGRVFVVFLVVISILWIPIIQSSNSGQLFDYIQAVTSYLAPPITALF 500

Query: 457 LLAIFWKRCNEQGAFYGGMAGFVLGAVRLILAFAYRAPECDQPDNRPGFIKDIHYMYVAT 516
           LLAIF KR  E GAF+G + G  +G +R+IL F+Y AP C + D RP  +KD HY+Y A 
Sbjct: 501 LLAIFCKRVTEPGAFWGLVFGLGVGLLRMILEFSYPAPACGEVDRRPAVLKDFHYLYFAI 560

Query: 517 GLFWVTGLITVIVSLLTPPPTKEQIRTTTFWSKKNLVVKENCSPKEEPYQMQEKSILRCS 576
            L  +T ++ VIVSL T P  +EQ+   T+W++       NC     P    EK      
Sbjct: 561 LLCGLTAIVIVIVSLCTTPIPEEQLTRLTWWTR-------NC-----PLSELEK------ 602

Query: 577 ENNETINHIIPNGKSEDSIKGLQPEDVNLLVTCREEGNPVASLGHSEAETPVDAYSNGQA 636
           E +E+   I      E    G   E+              +SLG  + E P  ++     
Sbjct: 603 EAHESTPEISERPAGECPAGGGAAEN--------------SSLGQEQPEAPSRSW----- 643

Query: 637 ALMGEKERKKETDDGGRYWKFIDWFCGFK---SKSLSKRSLRDLMEEEAVCLQMLEETRQ 693
                         G   W    WFCG      ++LS      L ++    L  +EE   
Sbjct: 644 --------------GKLLW---SWFCGLSGTPEQALSPAEKAALEQK----LTSIEEEPL 682

Query: 694 VKVILNIGLFAVCSLGIFMFVYFS 717
            + + NI    + ++ IF++ YF+
Sbjct: 683 WRHVCNINAVLLLAINIFLWGYFA 706


>gi|4507033 solute carrier family 5 (sodium/glucose cotransporter),
           member 2 [Homo sapiens]
          Length = 672

 Score =  608 bits (1569), Expect = e-174
 Identities = 291/563 (51%), Positives = 414/563 (73%), Gaps = 2/563 (0%)

Query: 2   RAVLDT-ADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNI 60
           +A++D  ADI ++A YF+LV+ +G ++M ++NR TV GYFLAGRSM W  +GASLF SNI
Sbjct: 17  KALIDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNI 76

Query: 61  GSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGH 120
           GS HF+GLAG+GAASG AV  +E+NAL ++ LLGW+F P+Y+ +GV TMP+YL KRFGG 
Sbjct: 77  GSGHFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGR 136

Query: 121 RIQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVA 180
           RI++Y + LSL LYIFTK+SVD++SGA+FIQ++LGWN+Y SVI L+G+T + TVTGGL A
Sbjct: 137 RIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAA 196

Query: 181 VIYTDTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCN 240
           ++YTDT+Q  +++ GA  LM  +  E+GG+  +  +Y+ A+  +T +     + N +S  
Sbjct: 197 LMYTDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLT-VSEDPAVGNISSFC 255

Query: 241 VSPKKEALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTL 300
             P+ ++  +LR+P   D+PWP  +LG T  S WYWC+DQVIVQR LA K++ H K   +
Sbjct: 256 YRPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCI 315

Query: 301 MAGFLKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVP 360
           + G+LKL PMF++V+PGMISRIL+ D++AC+ PE C  VCG+  GCSNIAYPRLV+KL+P
Sbjct: 316 LCGYLKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPRLVVKLMP 375

Query: 361 VGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVV 420
            GLRGLM+AVM+AALMS L SIFNS+ST+FT+D+Y  +R  A  REL++VGR++V F+VV
Sbjct: 376 NGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGRLWVVFIVV 435

Query: 421 ISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVL 480
           +S+AW+P++   QGGQ++ YIQ V+ YL PPV+A+F+LA+F  R NEQGAF+G + G ++
Sbjct: 436 VSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGLIGGLLM 495

Query: 481 GAVRLILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVIVSLLTPPPTKEQ 540
           G  RLI  F++ +  C QP   P F+  +HY+Y A  LF+ +GL+T+ VSL T P  ++ 
Sbjct: 496 GLARLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLLTLTVSLCTAPIPRKH 555

Query: 541 IRTTTFWSKKNLVVKENCSPKEE 563
           +    F  + +   +E+    E+
Sbjct: 556 LHRLVFSLRHSKEEREDLDADEQ 578


>gi|109659836 solute carrier family 5 (sodium/glucose
           cotransporter), member 10 isoform 2 [Homo sapiens]
          Length = 596

 Score =  595 bits (1534), Expect = e-170
 Identities = 277/544 (50%), Positives = 395/544 (72%), Gaps = 9/544 (1%)

Query: 5   LDTADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNIGSEH 64
           L  ADI ++ +YF L + +G ++  +++R+TV+GYFLAGR MTW  IGASLF S+ GS  
Sbjct: 16  LSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGL 75

Query: 65  FIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQV 124
           FIGLAGSGAA G AV  +E+NA  +L  L WVF+PIYI S + T+PEY+ KR+GG RI++
Sbjct: 76  FIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRM 135

Query: 125 YFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYT 184
           Y + LSL+L +FTK+S+DLY+GALF+   LGWN Y+S IL +G+TAL T+ GGL AVIYT
Sbjct: 136 YLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYT 195

Query: 185 DTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSPK 244
           D LQ L+M++GA+ L I +  +IGG+ +++  Y  A P  T       ++NT +C++ P+
Sbjct: 196 DALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRT-------IANT-TCHL-PR 246

Query: 245 KEALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGF 304
            +A+ M R+P   D+PW G   G T  + WYWC DQVIVQR L+A+++ HAK  +++A +
Sbjct: 247 TDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASY 306

Query: 305 LKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVPVGLR 364
           LK+LPM +I++PGMISR LF DD+ C+ P  C+  CG+  GCSNIAYP+LVM+L+P+GLR
Sbjct: 307 LKMLPMGLIIMPGMISRALFPDDVGCVVPSECLRACGAEVGCSNIAYPKLVMELMPIGLR 366

Query: 365 GLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISIA 424
           GLM+AVM+AALMS L SIFNS+ST+FT+D+++ +R  +  REL++VGR+ +  ++ +S+A
Sbjct: 367 GLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLVIVALIGVSVA 426

Query: 425 WVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAVR 484
           W+P++ +   GQ+++Y+Q V   L PPV A+F+L +FW+R NEQGAF+G +AG V+GA R
Sbjct: 427 WIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLIAGLVVGATR 486

Query: 485 LILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVIVSLLTPPPTKEQIRTT 544
           L+L F   AP C +PD RP  +  IHY++ A  LF ++G + V  SLLTPPP   QI   
Sbjct: 487 LVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLLTPPPQSVQIENL 546

Query: 545 TFWS 548
           T+W+
Sbjct: 547 TWWT 550


>gi|109659839 solute carrier family 5 (sodium/glucose
           cotransporter), member 10 isoform 1 [Homo sapiens]
          Length = 612

 Score =  587 bits (1513), Expect = e-167
 Identities = 278/560 (49%), Positives = 396/560 (70%), Gaps = 25/560 (4%)

Query: 5   LDTADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNIGSEH 64
           L  ADI ++ +YF L + +G ++  +++R+TV+GYFLAGR MTW  IGASLF S+ GS  
Sbjct: 16  LSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGL 75

Query: 65  FIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQV 124
           FIGLAGSGAA G AV  +E+NA  +L  L WVF+PIYI S + T+PEY+ KR+GG RI++
Sbjct: 76  FIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRM 135

Query: 125 YFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYT 184
           Y + LSL+L +FTK+S+DLY+GALF+   LGWN Y+S IL +G+TAL T+ GGL AVIYT
Sbjct: 136 YLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYT 195

Query: 185 DTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSPK 244
           D LQ L+M++GA+ L I +  +IGG+ +++  Y  A P  T       ++NT +C++ P+
Sbjct: 196 DALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRT-------IANT-TCHL-PR 246

Query: 245 KEALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGF 304
            +A+ M R+P   D+PW G   G T  + WYWC DQVIVQR L+A+++ HAK  +++A +
Sbjct: 247 TDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASY 306

Query: 305 LKLLPMFIIVVPGMISRILF----------------TDDIACINPEHCMLVCGSRAGCSN 348
           LK+LPM +I++PGMISR LF                TDD+ C+ P  C+  CG+  GCSN
Sbjct: 307 LKMLPMGLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSN 366

Query: 349 IAYPRLVMKLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELM 408
           IAYP+LVM+L+P+GLRGLM+AVM+AALMS L SIFNS+ST+FT+D+++ +R  +  REL+
Sbjct: 367 IAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELL 426

Query: 409 IVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQ 468
           +VGR+ +  ++ +S+AW+P++ +   GQ+++Y+Q V   L PPV A+F+L +FW+R NEQ
Sbjct: 427 LVGRLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQ 486

Query: 469 GAFYGGMAGFVLGAVRLILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVI 528
           GAF+G +AG V+GA RL+L F   AP C +PD RP  +  IHY++ A  LF ++G + V 
Sbjct: 487 GAFWGLIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVA 546

Query: 529 VSLLTPPPTKEQIRTTTFWS 548
            SLLTPPP   QI   T+W+
Sbjct: 547 GSLLTPPPQSVQIENLTWWT 566


>gi|14140236 solute carrier family 5 (low affinity glucose
           cotransporter), member 4 [Homo sapiens]
          Length = 659

 Score =  572 bits (1473), Expect = e-163
 Identities = 267/532 (50%), Positives = 387/532 (72%), Gaps = 4/532 (0%)

Query: 4   VLDTADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNIGSE 63
           + + ADI+++ +YF++VM +G +AM K+NR T+ G+FLAGR M W  +GASLF SNIGS 
Sbjct: 23  IRNAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSN 82

Query: 64  HFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQ 123
           H++GLAG+GAASG A   +E+ + ++L +LGW+F+PIYI+SGV TMPEYL KRFGG R+Q
Sbjct: 83  HYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQ 142

Query: 124 VYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIY 183
           VY + LSL + +   +S D+++GA+FI+ +LG +LY+++ +L+ MTA+ T TGGL +VIY
Sbjct: 143 VYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIY 202

Query: 184 TDTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSP 243
           TDTLQ ++M+IG+  LM  +  E+GG+E    +Y+ A+P   S++   NL+ + SC  +P
Sbjct: 203 TDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATP---SVVEGDNLTISASC-YTP 258

Query: 244 KKEALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAG 303
           + ++  + R+    D+PWPG I G    ++WYWC +QVIVQR L  K+++H K + +M  
Sbjct: 259 RADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCA 318

Query: 304 FLKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVPVGL 363
           +LKLLPMF++V+PGMISRIL+TD +AC+ P  C+  CG   GC+N AYP +V++L+P GL
Sbjct: 319 YLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQGL 378

Query: 364 RGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISI 423
           RGLM++VM+A+LMS L SIFNSAST+FT+D+Y  +RK AS +EL+I GRIFV  + V+SI
Sbjct: 379 RGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIFVLLLTVVSI 438

Query: 424 AWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAV 483
            WVP++   Q GQ+  Y + ++ YL PP+AA+F+LAIF KR NEQGAF+G M G  +G +
Sbjct: 439 VWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLAMGLI 498

Query: 484 RLILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVIVSLLTPP 535
           R+I  FAY    C  P N P  I  +HY+Y +  LF+ + L+T+ +SLLT P
Sbjct: 499 RMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLVTLGISLLTKP 550


>gi|157671931 solute carrier family 5 (sodium/glucose
           cotransporter), member 12 [Homo sapiens]
          Length = 618

 Score =  111 bits (278), Expect = 2e-24
 Identities = 145/632 (22%), Positives = 256/632 (40%), Gaps = 77/632 (12%)

Query: 10  IAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNIGSEHFIGLA 69
           +   AL+FI      FFA+ +  ++T   + + GR M++  +G SL  S + +   +G  
Sbjct: 12  VVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVTVLGTP 71

Query: 70  GSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAAL 129
                 G +   +    L ++ L   +F+P++ RSG+ +  EYL  RF  ++   Y A +
Sbjct: 72  SEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRF--NKPVRYAATV 129

Query: 130 SLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQA 189
             I+       V +Y+ AL + +  G++L+ SV     +       GGL AV++TD  Q 
Sbjct: 130 IYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAFQM 189

Query: 190 LLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSPKKEALK 249
           ++MI+G LT++I      GGF  V  +                  +TN   +      + 
Sbjct: 190 VVMIVGFLTVLIQGSTHAGGFHNVLEQ------------------STNGSRLHIFDFDVD 231

Query: 250 MLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLP 309
            LR  T     W    +G T   +  +  +Q  +QR ++ K   HAK    +A +  LL 
Sbjct: 232 PLRRHTF----WT-ITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAK----LALYFNLLG 282

Query: 310 MFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVPV--GLRGLM 367
           ++II+V  + S ++        +P    ++        +   P  VM++     GL GL 
Sbjct: 283 LWIILVCAVFSGLIMYSHFKDCDPWTSGII-----SAPDQLMPYFVMEIFATMPGLPGLF 337

Query: 368 MAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISIAWVP 427
           +A   +  +S + S  N+ +T+   D  K      S +    + +       V+  + + 
Sbjct: 338 VACAFSGTLSTVASSINALATVTFEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTS-MA 396

Query: 428 IIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAVRLIL 487
           +   + GG +   +  +      P+  LF L I +   N +GA  G + G  L     I 
Sbjct: 397 VAASVMGGVVQASL-SIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAIG 455

Query: 488 AFAYRAP------------ECDQPD----------NRPGFIK---DIHYMYVATGLFWVT 522
           AF Y AP            +C + +          +RPG       I Y+Y +       
Sbjct: 456 AFIYPAPASKTWPLPLSTDQCIKSNVTATGPPVLSSRPGIADTWYSISYLYYSAVGCLGC 515

Query: 523 GLITVIVSLLTPPPTKEQIRTT---------TFWSKKNLVVKENCSPKEEPYQMQEKSIL 573
            +  VI+SL+T     E I+            FWSKK   +   C  + +    QE ++ 
Sbjct: 516 IVAGVIISLITGRQRGEDIQPLLIRPVCNLFCFWSKKYKTLCW-CGVQHDSGTEQE-NLE 573

Query: 574 RCSENNETINHIIPNGKSEDS---IKGLQPED 602
             S   +    ++ NG   +S   + G  P+D
Sbjct: 574 NGSARKQGAESVLQNGLRRESLVHVPGYDPKD 605


>gi|4507035 solute carrier family 5 (sodium iodide symporter),
           member 5 [Homo sapiens]
          Length = 643

 Score =  102 bits (254), Expect = 1e-21
 Identities = 104/479 (21%), Positives = 200/479 (41%), Gaps = 46/479 (9%)

Query: 9   DIAIVALYFILVMCIGFFA-MWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNIGSEHFIG 67
           D  + AL  ++   IG +  + +  + +   +F  GR +  + +G SL  S + +   +G
Sbjct: 16  DYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLG 75

Query: 68  LAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFA 127
           +       G          LL   L   +F+P++ R G+ +  EYL  RF   R      
Sbjct: 76  VPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFS--RAVRLCG 133

Query: 128 ALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTL 187
            L  I+       + +Y+ AL + +  G +++ S++    +    T  GG+ AV++TD  
Sbjct: 134 TLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTDVF 193

Query: 188 QALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSPKKEA 247
           Q ++M+ G   ++   +M +GG  +V             + L  N S  N  + +P    
Sbjct: 194 QVVVMLSGFWVVLARGVMLVGGPRQV-------------LTLAQNHSRINLMDFNP---- 236

Query: 248 LKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKL 307
                +P      W  F++G T   +  +  +Q  VQR +A +    AK    +A  +  
Sbjct: 237 -----DPRSRYTFWT-FVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAK----LALLINQ 286

Query: 308 LPMFIIVVP----GMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVP--V 361
           + +F+IV      G++  + +TD         C  +   R    +   P LV+ +     
Sbjct: 287 VGLFLIVSSAACCGIVMFVFYTD---------CDPLLLGRISAPDQYMPLLVLDIFEDLP 337

Query: 362 GLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVI 421
           G+ GL +A   +  +S   +  N+ + +   D+ K   +S + R+L+I+ +  ++ +   
Sbjct: 338 GVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRLRSLAPRKLVIISK-GLSLIYGS 396

Query: 422 SIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVL 480
           +   V  +  + GG +      V   ++ P+   F+L +F   CN  G   G  AG  L
Sbjct: 397 ACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFILGMFLPACNTPGVLAGLGAGLAL 455


>gi|167466278 solute carrier family 5 (iodide transporter), member 8
           [Homo sapiens]
          Length = 610

 Score = 93.6 bits (231), Expect = 6e-19
 Identities = 104/476 (21%), Positives = 192/476 (40%), Gaps = 41/476 (8%)

Query: 9   DIAIVALYFILVMCIG-FFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNIGSEHFIG 67
           D  + A   ++   IG ++A     + T   + + GR MT V +  SL  S + +   +G
Sbjct: 14  DYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAVTVLG 73

Query: 68  LAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFA 127
                   G     + F    ++ +   VF+P++ + G+ +  EYL  RF  ++      
Sbjct: 74  TPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRF--NKCVRLCG 131

Query: 128 ALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTL 187
            +  I+       + +Y+ AL + +  G++L+ +V+    +       GGL AVI+TD  
Sbjct: 132 TVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTDVF 191

Query: 188 QALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSPKKEA 247
           Q  +M+ G  +++I +++  GG               T +   Y+    N  N +P    
Sbjct: 192 QVGIMVAGFASVIIQAVVMQGGIS-------------TILNDAYDGGRLNFWNFNP---- 234

Query: 248 LKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKL 307
                NP      W   I+G T      +  +Q  VQR ++ K+   AK    ++ ++ L
Sbjct: 235 -----NPLQRHTFWT-IIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAK----LSLYINL 284

Query: 308 LPMFIIVVPGMISRILFTDDIACINPEH-CMLVCGSRAGCSNIAYPRLVMKLVP--VGLR 364
           + ++ I+   +         +A  +  H C      +    +   P LV+ ++    GL 
Sbjct: 285 VGLWAILTCSVFC------GLALYSRYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLP 338

Query: 365 GLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISIA 424
           GL +A   +  +S + S  N+ + +   D+ K   +S S R L  + +        + I 
Sbjct: 339 GLFVACAYSGTLSTVSSSINALAAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIG 398

Query: 425 WVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVL 480
              +   M  G +      V   +  P+  LF L I     N  GA  G MAGF +
Sbjct: 399 MAALASLM--GALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGLMAGFAI 452


>gi|10863879 solute carrier family 5 (sodium-dependent vitamin
           transporter), member 6 [Homo sapiens]
          Length = 635

 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 113/508 (22%), Positives = 212/508 (41%), Gaps = 53/508 (10%)

Query: 9   DIAIVALYFILVMCIGFFAMWKS-NRSTVSGYFLAGRSMTWVTIGASLFVSNIGSEHFIG 67
           D  +  L  +L + IG +   +   R TV    +A R M  + +  SL  +   +   +G
Sbjct: 28  DYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAILG 87

Query: 68  LAGSGAASGFAVGAWEFNALLLLQLL--GWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVY 125
           +        F    W       L LL    +FIP++ R  + +  EYL  RF  ++    
Sbjct: 88  VPSE--IYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRF--NKTVRV 143

Query: 126 FAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTD 185
              ++ I  +   + V LY+ +L +    G++L++SV+ L  +  + T  GGL AVI+TD
Sbjct: 144 CGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIWTD 203

Query: 186 TLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSPKK 245
             Q L+M +G L ++I+   ++GG   V   + +AS               +   + P  
Sbjct: 204 VFQTLVMFLGQLAVIIVGSAKVGGLGRV---WAVASQH----------GRISGFELDP-- 248

Query: 246 EALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFL 305
                  +P      W     G     +  +  +Q  VQR L+++     K + L    +
Sbjct: 249 -------DPFVRHTFWT-LAFGGVFMMLSLYGVNQAQVQRYLSSRT---EKAAVLSCYAV 297

Query: 306 KLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSN--IAYPRLVMKLVPVGL 363
                  + V  +I  ++F         E+ M +  ++A      + +   ++K +P GL
Sbjct: 298 FPFQQVSLCVGCLIGLVMF-----AYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLP-GL 351

Query: 364 RGLMMAVMIAALMSDLDSIFNSASTIFTLDVYK-LIRKSASSRELMIV-GRIFVAFMVVI 421
            GL +A + +  +S + S FNS +T+   D+ +    + + +R +M+  G  F   ++ +
Sbjct: 352 PGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCL 411

Query: 422 SIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFV-- 479
            +A+    +  Q G +      +   +  P+  LF L +F+   N  GA  G +AG V  
Sbjct: 412 GMAY----ISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMA 467

Query: 480 --LGAVRLILAFAYRAPECDQPDNRPGF 505
             +G   ++ +  +  P    P N   F
Sbjct: 468 FWIGIGSIVTSMGFSMP--PSPSNGSSF 493


>gi|11141885 solute carrier family 5 (choline transporter), member 7
           [Homo sapiens]
          Length = 580

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 115/487 (23%), Positives = 209/487 (42%), Gaps = 66/487 (13%)

Query: 10  IAIVALYFILVMCIGFFAMWKSNRSTVS-----GYFLAGRSMTWVTIGASLFVSNIGSEH 64
           IAI+  Y +L++ +G +A W++  S  +        + GR +  +  G ++  + +G  +
Sbjct: 9   IAIIVFY-LLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGY 67

Query: 65  FIGLAGSGAASGFAVGAWEFNAL--LLLQLLGWVFIPIYIRS-GVYTMPEYLSKRFGGHR 121
             G A +    G+ + AW    +   L  +LG +F    +RS G  TM +          
Sbjct: 68  INGTAEAVYVPGYGL-AWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQ------- 119

Query: 122 IQVYFAALSLILYIFTKLSVDLYSGALF------IQESLGWNLYVSVILLIGMTALLTVT 175
            Q+Y   +  +L+I   +    ++ A+F      I   +  ++++SVI+   +  L T+ 
Sbjct: 120 -QIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLV 178

Query: 176 GGLVAVIYTDTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSN 235
           GGL +V YTD +Q   + +G    + IS+            + L+ P V  I  T     
Sbjct: 179 GGLYSVAYTDVVQLFCIFVG----LWISVP-----------FALSHPAVADIGFTA---- 219

Query: 236 TNSCNVSPKKEALKMLRNPTDEDVPW-PGFILGQTPASVWYWCADQVIVQRVLAAKNIAH 294
                V  K +   +    + E   W   F+L       W     Q   QRVL++ +  +
Sbjct: 220 -----VHAKYQKPWLGTVDSSEVYSWLDSFLLLMLGGIPW-----QAYFQRVLSSSSATY 269

Query: 295 AKGSTLMAGFLKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRL 354
           A+  + +A F  L+     ++ G I      +  A   P+            +++  P +
Sbjct: 270 AQVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGLPDP------KTTEEADMILPIV 323

Query: 355 VMKLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKL-IRKSASSRELMIVGRI 413
           +  L PV +    +  + AA+MS  DS   SAS++F  ++Y+L  R++AS +E++ V RI
Sbjct: 324 LQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRI 383

Query: 414 FVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYG 473
            V F+   S   + ++ +   G  YL    V   + P +    L  +F K  N  GA  G
Sbjct: 384 TV-FVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQL----LCVLFVKGTNTYGAVAG 438

Query: 474 GMAGFVL 480
            ++G  L
Sbjct: 439 YVSGLFL 445


>gi|21361581 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 13 [Homo sapiens]
          Length = 602

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 38/129 (29%), Positives = 61/129 (47%), Gaps = 14/129 (10%)

Query: 339 VCGSRAGCSNIAYPRLVMKLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFT--LDVYK 396
           V  S  G + IAYPR V+ L    L       M+  L   LDS F    ++ T  +D+Y 
Sbjct: 350 VAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLL--GLDSQFVCVESLVTALVDMYP 407

Query: 397 LIRKSASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALF 456
            + +  + RE++I+G   V+F+       V +I+  +GG   +Y+ ++ DY       L 
Sbjct: 408 HVFRKKNRREVLILGVSVVSFL-------VGLIMLTEGG---MYVFQLFDYYAASGMCLL 457

Query: 457 LLAIFWKRC 465
            +AIF   C
Sbjct: 458 FVAIFESLC 466


>gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]
          Length = 237

 Score = 37.0 bits (84), Expect = 0.064
 Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 4/78 (5%)

Query: 129 LSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTG--GLVAVIYTDT 186
           L L L I+ ++S D  S A+F  E +G + YV+V +LI + A++ + G  G    I    
Sbjct: 25  LILALAIWVRVSND--SQAIFGSEDVGSSSYVAVDILIAVGAIIMILGFLGCCGAIKESR 82

Query: 187 LQALLMIIGALTLMIISI 204
              LL  IG L ++++ +
Sbjct: 83  CMLLLFFIGLLLILLLQV 100


>gi|188528618 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 1 [Homo sapiens]
          Length = 599

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 14/135 (10%)

Query: 339 VCGSRAGCSNIAYPRLVMKLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLI 398
           V  S  G + +AYP  V +L    L  ++   M+  LM  +DS F +     T  V +  
Sbjct: 356 VAASGPGLAFLAYPEAVTQLPISPLWAILFFSML--LMLGIDSQFCTVEGFITALVDEYP 413

Query: 399 RKSASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLL 458
           R   + REL I     +++++ +S          QGG   +Y+ ++ DY +    +L  L
Sbjct: 414 RLLRNRRELFIAAVCIISYLIGLSNI-------TQGG---IYVFKLFDYYSASGMSLLFL 463

Query: 459 AIFWKRCNEQGAFYG 473
             F   C     FYG
Sbjct: 464 VFF--ECVSISWFYG 476


>gi|197276623 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform a [Homo sapiens]
          Length = 620

 Score = 33.1 bits (74), Expect = 0.92
 Identities = 34/136 (25%), Positives = 56/136 (41%), Gaps = 12/136 (8%)

Query: 339 VCGSRAGCSNIAYPRLVMKLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLI 398
           V  S  G + IAYP+ V  +       ++  +M+  L  D   +         +D+Y   
Sbjct: 362 VAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSF 421

Query: 399 RKSASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLL 458
            +    RE      IF+AF  V SI+++  +  +  G MY++  ++ DY       L  +
Sbjct: 422 LRKGYRRE------IFIAF--VCSISYLLGLTMVTEGGMYVF--QLFDYYAASGVCLLWV 471

Query: 459 AIFWKRCNEQGAFYGG 474
           A F   C      YGG
Sbjct: 472 AFF--ECFVIAWIYGG 485


>gi|54607094 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform a [Homo sapiens]
          Length = 620

 Score = 33.1 bits (74), Expect = 0.92
 Identities = 34/136 (25%), Positives = 56/136 (41%), Gaps = 12/136 (8%)

Query: 339 VCGSRAGCSNIAYPRLVMKLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLI 398
           V  S  G + IAYP+ V  +       ++  +M+  L  D   +         +D+Y   
Sbjct: 362 VAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSF 421

Query: 399 RKSASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLL 458
            +    RE      IF+AF  V SI+++  +  +  G MY++  ++ DY       L  +
Sbjct: 422 LRKGYRRE------IFIAF--VCSISYLLGLTMVTEGGMYVF--QLFDYYAASGVCLLWV 471

Query: 459 AIFWKRCNEQGAFYGG 474
           A F   C      YGG
Sbjct: 472 AFF--ECFVIAWIYGG 485


>gi|7657587 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 11 [Homo sapiens]
          Length = 632

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 35/137 (25%), Positives = 62/137 (45%), Gaps = 16/137 (11%)

Query: 339 VCGSRAGCSNIAYPRLVMKLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFT--LDVYK 396
           V  S  G + IAYP+ V  +    L   +  +M+  L   LDS F    ++ T  +D+Y 
Sbjct: 370 VAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFL--GLDSQFVCVESLVTAVVDMYP 427

Query: 397 LIRKSASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALF 456
            + +    REL+I+    +++       ++ +++  +GG   +YI ++ D        L 
Sbjct: 428 KVFRRGYRRELLILALSVISY-------FLGLVMLTEGG---MYIFQLFDSYAASGMCLL 477

Query: 457 LLAIFWKRCNEQGAFYG 473
            +AIF   C   G  YG
Sbjct: 478 FVAIF--ECICIGWVYG 492


>gi|197333868 T-box 2 [Homo sapiens]
          Length = 712

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 21/85 (24%), Positives = 37/85 (43%)

Query: 250 MLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLP 309
           M+    D ++P   +I   +PA+   W A  V   ++    NI+   G T++    K  P
Sbjct: 173 MVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQP 232

Query: 310 MFIIVVPGMISRILFTDDIACINPE 334
            F IV    I ++ ++     + PE
Sbjct: 233 RFHIVRANDILKLPYSTFRTYVFPE 257


>gi|156139155 guanine nucleotide binding protein, alpha transducing
           3 [Homo sapiens]
          Length = 354

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 15/42 (35%), Positives = 28/42 (66%)

Query: 180 AVIYTDTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLAS 221
           AVIY++TLQ++L I+ A+T + I  +     E+ ++ Y +A+
Sbjct: 71  AVIYSNTLQSILAIVKAMTTLGIDYVNPRSAEDQRQLYAMAN 112


>gi|193083148 cytochrome P450 family 2 subfamily C polypeptide 18
           isoform 2 [Homo sapiens]
          Length = 431

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 18/44 (40%), Positives = 27/44 (61%), Gaps = 4/44 (9%)

Query: 652 GRYWKFIDWFC--GFKSKSLSKRSLRDLMEEEAVCLQMLEETRQ 693
           G+ WK I  FC    ++  + KRS+ D ++EEA CL  +EE R+
Sbjct: 117 GKRWKEIRRFCLMTLRNFGMGKRSIEDRVQEEARCL--VEELRK 158


>gi|13699816 cytochrome P450 family 2 subfamily C polypeptide 18
           isoform 1 [Homo sapiens]
          Length = 490

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 18/44 (40%), Positives = 27/44 (61%), Gaps = 4/44 (9%)

Query: 652 GRYWKFIDWFC--GFKSKSLSKRSLRDLMEEEAVCLQMLEETRQ 693
           G+ WK I  FC    ++  + KRS+ D ++EEA CL  +EE R+
Sbjct: 117 GKRWKEIRRFCLMTLRNFGMGKRSIEDRVQEEARCL--VEELRK 158


>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
          Length = 3092

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 2/52 (3%)

Query: 639 MGEKERKKETDDGGRYWKFIDWFCGFKSKSLSKRSLRDLMEEEAVCLQMLEE 690
           M E+ R+ +T D  R+W+ I  FC    K L+  SL  L+E+   C ++LE+
Sbjct: 928 MPEEGRQFQTVD--RHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEK 977


>gi|40789261 solute carrier family 16, member 6 [Homo sapiens]
          Length = 523

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 16/86 (18%)

Query: 413 IFVAFMV-VISIAWVPIIVE---------MQGGQMYLYIQEVADYLTPPVAALFL-LAIF 461
           IF  FMV  I    +P++ E              +Y++IQ +A    PP+A L +  +  
Sbjct: 390 IFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQSKI 449

Query: 462 WKRCNEQGAFYGGMAGFVLGAVRLIL 487
           + R     AFY   AG  L AV L L
Sbjct: 450 YSR-----AFYSCAAGMALAAVCLAL 470


>gi|61966919 hypothetical protein LOC442444 [Homo sapiens]
          Length = 1035

 Score = 30.4 bits (67), Expect = 6.0
 Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 2/60 (3%)

Query: 575 CSENNET-INHIIPNGKSEDSIKGLQPEDVNLLVTCREEGNPVASLGHSEAETPVDAYSN 633
           C E  +T ++H+ P   SE  +  L+PE   +LV+   +  P +S+ H   E P    S+
Sbjct: 499 CPEPPKTRVSHLRPE-PSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSH 557


>gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]
          Length = 723

 Score = 30.0 bits (66), Expect = 7.8
 Identities = 20/85 (23%), Positives = 37/85 (43%)

Query: 250 MLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLP 309
           M+    D ++P   +I   +PA+   W +  V   ++    NI+   G T++    K  P
Sbjct: 171 MVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTILNSMHKYQP 230

Query: 310 MFIIVVPGMISRILFTDDIACINPE 334
            F IV    I ++ ++     + PE
Sbjct: 231 RFHIVRANDILKLPYSTFRTYLFPE 255


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,472,986
Number of Sequences: 37866
Number of extensions: 1125579
Number of successful extensions: 3601
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 3555
Number of HSP's gapped (non-prelim): 42
length of query: 718
length of database: 18,247,518
effective HSP length: 110
effective length of query: 608
effective length of database: 14,082,258
effective search space: 8562012864
effective search space used: 8562012864
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.