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Search of human proteins with 169167715
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
(285 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 576 e-165
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 184 8e-47
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 184 8e-47
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 175 5e-44
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 170 1e-42
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 166 2e-41
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 160 9e-40
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 130 1e-30
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 130 1e-30
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 127 9e-30
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 127 1e-29
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 122 3e-28
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 108 4e-24
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 103 1e-22
gi|148746195 trichohyalin [Homo sapiens] 101 7e-22
gi|52426743 cisplatin resistance-associated overexpressed protei... 101 9e-22
gi|19923485 cisplatin resistance-associated overexpressed protei... 101 9e-22
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 100 2e-21
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 98 9e-21
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 97 2e-20
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 96 5e-20
gi|213385278 TNF receptor-associated factor 3 interacting protei... 94 1e-19
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 92 4e-19
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 92 4e-19
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 92 7e-19
gi|20070262 TNF receptor-associated factor 3 interacting protein... 90 2e-18
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 90 2e-18
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 89 4e-18
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 88 7e-18
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 88 1e-17
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 576 bits (1484), Expect = e-165
Identities = 285/285 (100%), Positives = 285/285 (100%)
Query: 1 MATYTDVKPLMMDTITESFSQLLLQTRPVSWRLAMRSQIEDRDVLILRGSRVAPAIIRER 60
MATYTDVKPLMMDTITESFSQLLLQTRPVSWRLAMRSQIEDRDVLILRGSRVAPAIIRER
Sbjct: 1 MATYTDVKPLMMDTITESFSQLLLQTRPVSWRLAMRSQIEDRDVLILRGSRVAPAIIRER 60
Query: 61 ERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETET 120
ERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETET
Sbjct: 61 ERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETET 120
Query: 121 ERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQ 180
ERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQ
Sbjct: 121 ERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQ 180
Query: 181 KQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDR 240
KQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDR
Sbjct: 181 KQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDR 240
Query: 241 QKAIDCVPGRWEVTVMAVDCVPGRWEVTVGDGRRLRAREVGGDRL 285
QKAIDCVPGRWEVTVMAVDCVPGRWEVTVGDGRRLRAREVGGDRL
Sbjct: 241 QKAIDCVPGRWEVTVMAVDCVPGRWEVTVGDGRRLRAREVGGDRL 285
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 184 bits (467), Expect = 8e-47
Identities = 115/248 (46%), Positives = 152/248 (61%), Gaps = 51/248 (20%)
Query: 14 TITESFSQLLL--QTRPVSWRLAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRK 71
TI FS+ L Q P SW L + D D +RQRER+R R+
Sbjct: 44 TIPLDFSRGRLGSQESPRSWGLGQAHKDADGD-----------------DRQRERDRVRE 86
Query: 72 RAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRD 131
+ EK+RDR RKRDRER+R ++++ R R DR+++TE ER ERE+Q+
Sbjct: 87 KT-----------EKERDRDRKRDRERRR-KEKETNRNR--DREKQTEIERDREREKQKG 132
Query: 132 RKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDR 191
R+RE+DR R+R+R+ +K+RE +TEKDRD +RE ETER RDRERE+QK+RET RDRDR
Sbjct: 133 RERERDRGRERERDRDREKERERQTEKDRDGQRET-ETERERDREREKQKERETERDRDR 191
Query: 192 ERQREKE-----DRERDR------------DRQKEREKDRYRERETGRDRDKERDRERQR 234
+R EKE DRERDR DR+ ERE DR RER+ RDR KERDRER R
Sbjct: 192 QRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDR 251
Query: 235 EKDRDRQK 242
+++R +++
Sbjct: 252 KEERKKER 259
Score = 145 bits (366), Expect = 4e-35
Identities = 80/184 (43%), Positives = 126/184 (68%), Gaps = 27/184 (14%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
RE+++ RERER R R E++RDR R+++RERQ +DRD G R+ E
Sbjct: 127 REKQKGRERERDRGR------------ERERDRDREKERERQTEKDRD------GQRETE 168
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRER 177
TE ER ERE+Q++R+ E+DR+RQR E K+RE +T+++RDR+R+ +TER R+ +R
Sbjct: 169 TERERDREREKQKERETERDRDRQRDTE----KERERQTDRERDRQRKT-QTERQRETDR 223
Query: 178 ERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKD 237
E +++ + RR+R R+R R KE R+R+RDR++ER+K+R +ER+ R KE+ +E +R +D
Sbjct: 224 EGERETDRRRERQRDRDRGKE-RDRERDRKEERKKERKKERKKER---KEKKKEEKRRED 279
Query: 238 RDRQ 241
+ R+
Sbjct: 280 KKRK 283
Score = 53.9 bits (128), Expect = 2e-07
Identities = 20/56 (35%), Positives = 43/56 (76%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGD 113
R RERQR+R+R ++R +ER R+++R+ E+ ++R+++R +++ + R+ K+ +WG+
Sbjct: 231 RRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 184 bits (467), Expect = 8e-47
Identities = 92/200 (46%), Positives = 146/200 (73%), Gaps = 16/200 (8%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRW-----RDRDRKRERWGD 113
E+ER+R+ +R+R+R ER+R+K+RE EK+R +R+R+R+R++ R +R RER +
Sbjct: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERE 215
Query: 114 RDRETETERQEERERQRDRKREKDRERQRQ--------REIGIDKDREIETEKDRDRERE 165
R+ ETETER+ + +R+RDR+R+ +RER++Q RE DK+RE E ++DRDR+R
Sbjct: 216 RETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRR 275
Query: 166 MGETERYRDRERERQKQRETRRDRDRERQREKE---DRERDRDRQKEREKDRYRERETGR 222
E ER DR+R+R+ +R+ +R RERQRE+E +R R R+R++ERE++R R+RET R
Sbjct: 276 QKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETER 335
Query: 223 DRDKERDRERQREKDRDRQK 242
DR+KER+R+R+R+ + DR++
Sbjct: 336 DREKERERKRKRQTEMDRER 355
Score = 184 bits (466), Expect = 1e-46
Identities = 90/191 (47%), Positives = 140/191 (73%), Gaps = 8/191 (4%)
Query: 58 RERER-QRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
R+R+R Q+ERERQ R ++R E+DRE E+ R+RQR+R+RER+R R R+R+RER +R+R
Sbjct: 270 RDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERER 329
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIG------IDKDREIETEKDRDREREMGETE 170
+ ETER E+ER+R RKR+ + +R+R R+ G +++RE E E+DR RE E E
Sbjct: 330 QRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERE 389
Query: 171 RYRDRERERQKQRETRRDRDRERQREKE-DRERDRDRQKEREKDRYRERETGRDRDKERD 229
R RDR+R+++++R+T +DRD +R+ EK+ +RE+DR+ ++ RE+ R RE++ GR+RD+ER
Sbjct: 390 RDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQ 449
Query: 230 RERQREKDRDR 240
+RQ + R R
Sbjct: 450 TDRQAGRQRKR 460
Score = 183 bits (465), Expect = 1e-46
Identities = 96/203 (47%), Positives = 146/203 (71%), Gaps = 20/203 (9%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDR-ERQRWRDRDRKRERWGDRDR 116
R+ ER+RE++ +R+RA ER E+D+E E++RDR R RDR +++R R DRKR+R +RDR
Sbjct: 236 RKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDR 295
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMG---ETERYR 173
ETE +R+ +RER+R+R+R + RER+R+RE +++R+ ETE+DR++ERE +TE R
Sbjct: 296 ETERKRERQRERERERERNRKRERERERER--ERERQRETERDREKERERKRKRQTEMDR 353
Query: 174 DRER----------ERQKQRETRRDRDRERQREKEDRERDRDRQKER----EKDRYRERE 219
+R R ER+++RE RDR R+RE+ +R+RDRDRQKER EKDR +RE
Sbjct: 354 ERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRE 413
Query: 220 TGRDRDKERDRERQREKDRDRQK 242
T + R++E+DRE +R ++R R++
Sbjct: 414 TEKQREREKDRESERGRERGRER 436
Score = 182 bits (462), Expect = 3e-46
Identities = 95/199 (47%), Positives = 140/199 (70%), Gaps = 17/199 (8%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEK----DRDRQRKRDRERQRWRDRDRKRERWGD 113
R+RER+RE++R RKR + R R++DRE E+ DR+R R+R++ER R ++R+R+ ER G+
Sbjct: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGE 136
Query: 114 RDRETETERQEERERQRD----RKREKDRERQRQREIGIDKDREIE------TEKDRDRE 163
R R+ +T+ Q ERERQRD R+R+ DRERQRQ E K+RE E E++R RE
Sbjct: 137 RGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQRE 196
Query: 164 REMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRD 223
+E +R+ +R RER+++RET + +R+RQ DRERDR R+ ERE+++ ERE +
Sbjct: 197 KENKTEDRHSERGRERERERETETETERKRQ---TDRERDRQRKTEREREKQAERERASE 253
Query: 224 RDKERDRERQREKDRDRQK 242
R+ ERD+ER+RE+DRDR +
Sbjct: 254 RETERDKERERERDRDRDR 272
Score = 179 bits (455), Expect = 2e-45
Identities = 98/202 (48%), Positives = 140/202 (69%), Gaps = 24/202 (11%)
Query: 58 RERERQRERE-----RQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWG 112
RERERQRE+E R +R +ER RE++ E E +R RQ R+R+RQR +R+R+++
Sbjct: 189 RERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAER 248
Query: 113 DRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERY 172
+R E ETER +ERER+RDR R++DR RQ++RE D+ R+ TE+DR ETER
Sbjct: 249 ERASERETERDKERERERDRDRDRDR-RQKERERQTDRKRQRRTERDR-------ETERK 300
Query: 173 RDRERERQKQRETRRDRDRERQREKE---DRERDRDRQKEREK--------DRYRERETG 221
R+R+RER+++RE R R+RER+RE+E RE +RDR+KERE+ DR R R+TG
Sbjct: 301 RERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360
Query: 222 RDRDKERDRERQREKDRDRQKA 243
R+ ++ +RER+RE++RDRQ A
Sbjct: 361 REGRRQAERERERERERDRQSA 382
Score = 172 bits (435), Expect = 4e-43
Identities = 93/225 (41%), Positives = 144/225 (64%), Gaps = 44/225 (19%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
+RER R+RE++R R KER RE +RE E+ RDRQ RER+R RD +++RER DR+R+
Sbjct: 110 DRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQR 169
Query: 119 ETER--QEERERQ-----------------------------RDRKREKDRERQRQREIG 147
+TER Q+ERER+ R+R+RE + E +R+R+
Sbjct: 170 QTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTD 229
Query: 148 IDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRER----- 202
++DR+ +TE++R+++ E ER +RE ER K+RE RDRDR+R R +++RER
Sbjct: 230 RERDRQRKTEREREKQ---AERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286
Query: 203 -----DRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQK 242
+RDR+ ER+++R RERE R+R+++R+RER+RE++R+RQ+
Sbjct: 287 RQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR 331
Score = 168 bits (426), Expect = 4e-42
Identities = 91/216 (42%), Positives = 143/216 (66%), Gaps = 30/216 (13%)
Query: 58 RERERQRERERQR-KRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
RER RQ+ERER+R KR ER ++ RE +++DR RKRDR R+R RDR+++RER DR+R
Sbjct: 54 RERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRER 113
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRERE-------MGET 169
+ + R++ER RQ++R+RE +RE +R R+ D RE E ++D ++ERE +T
Sbjct: 114 DRQ--REKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT 171
Query: 170 ERYRDRERERQKQRETRRDRDRERQREKE------DRERDRDRQKEREKDRYRERETGRD 223
ER R +ERER+K R+ RR+R+R+R++E + +R R+R+R++E E + R+R+T R+
Sbjct: 172 ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
Query: 224 RDKERDRERQREK--------------DRDRQKAID 245
RD++R ER+REK D++R++ D
Sbjct: 232 RDRQRKTEREREKQAERERASERETERDKERERERD 267
Score = 120 bits (301), Expect = 1e-27
Identities = 67/172 (38%), Positives = 105/172 (61%), Gaps = 13/172 (7%)
Query: 84 IEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEER-----------ERQRDR 132
I D R+R +E R R + + DRE +++ ER +R+R+R
Sbjct: 22 IPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRER 81
Query: 133 KREKDRERQRQREIGIDKDREIETEKDRDRERE-MGETERYRDRERERQKQRETRRDRDR 191
+REKDR R+R R +DRE E E+ DRER+ E ER R +ERER+ +RE R RDR
Sbjct: 82 RREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDR 141
Query: 192 ERQREKE-DRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQK 242
+ ++E +R+RD ++++ER+ DR R+R+T R+R KER+RE+ R++ R+R++
Sbjct: 142 QTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERER 193
Score = 111 bits (278), Expect = 6e-25
Identities = 66/164 (40%), Positives = 102/164 (62%), Gaps = 25/164 (15%)
Query: 84 IEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQ 143
++ R R ++ R+R + K DR+R + ER+ RE+ R +RE DR+R+R+
Sbjct: 24 LDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREK-RQTERETDRKRERR 82
Query: 144 REIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERD 203
RE KDR R+R+ R+R+R+R+R+K+RE + DR+R+RQREKE
Sbjct: 83 RE------------KDRHRKRD-----RHRERQRDREKERERQTDRERDRQREKE----- 120
Query: 204 RDRQKEREKDRYRERETGRDR--DKERDRERQREKDRDRQKAID 245
R+RQKERE++ RE E GRDR D +R+RERQR+ +++R++ D
Sbjct: 121 RNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTD 164
Score = 100 bits (248), Expect = 2e-21
Identities = 62/161 (38%), Positives = 91/161 (56%), Gaps = 48/161 (29%)
Query: 58 RERERQRERERQRKRAKERHREKDRE------------------------IEKDRDRQRK 93
RERER+RERER+R+R ER REK+RE E++R+R+R+
Sbjct: 317 RERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERE 376
Query: 94 RDR---------ERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQR 144
RDR ER R RDR ++RER ++DR+ + E +++RER++DR+ E+ RER R+R
Sbjct: 377 RDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRER 436
Query: 145 EIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRET 185
E +K R+R+R ER DR+ RQ++R T
Sbjct: 437 ----------EKQKGRERDR-----ERQTDRQAGRQRKRST 462
Score = 88.2 bits (217), Expect = 7e-18
Identities = 52/125 (41%), Positives = 78/125 (62%), Gaps = 19/125 (15%)
Query: 132 RKREKDRERQRQREIGI------DKDREIETEKDRDREREMGETERYRDRERERQKQRET 185
R+R +E R+R +G DRE +K+R+R RE +TER DR+RER
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRER------ 81
Query: 186 RRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAID 245
RR++DR R+R++ RER RDR+KERE R+T R+RD++R++ER R+K+R+R+ +
Sbjct: 82 RREKDRHRKRDRH-RERQRDREKERE------RQTDRERDRQREKERNRQKERERETERE 134
Query: 246 CVPGR 250
GR
Sbjct: 135 GERGR 139
Score = 80.9 bits (198), Expect = 1e-15
Identities = 55/143 (38%), Positives = 79/143 (55%), Gaps = 9/143 (6%)
Query: 146 IGIDKDREIETEKDRDREREMGETERYRD---RERERQKQRETRRDRDRERQREKE-DRE 201
I +D R ++ R R +G+ + D RER RQK+RE RR++ RQ E+E DR+
Sbjct: 22 IPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREK---RQTERETDRK 78
Query: 202 RDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAIDCVPGRWEVTVMAVDCV 261
R+R R+K+R + R R RE RDR+KER+R+ RE+DR R+K + R T +
Sbjct: 79 RERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGE-- 136
Query: 262 PGRWEVTVGDGRRLRAREVGGDR 284
GR T G R R R+ +R
Sbjct: 137 RGRDRQTDGQRERERQRDAEKER 159
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 175 bits (443), Expect = 5e-44
Identities = 91/202 (45%), Positives = 145/202 (71%), Gaps = 21/202 (10%)
Query: 58 RERERQRERERQRKRAKE-----RHREKDREIEKDRDRQRKRDRERQRWRDRD--RKRER 110
R+RER+RE +R+R RAKE RH E+DR+ +++R+R+R RDRER++ DR+ R+RER
Sbjct: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRER 78
Query: 111 WGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRER--EMGE 168
DRDR+ ETER+ ++ER+ DR E DRERQ+Q+E RE+E +DR+RE+ EMG
Sbjct: 79 ERDRDRQRETERERDKERETDRHTETDRERQKQKE------REMERVRDREREKQKEMGR 132
Query: 169 TERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRE-----RETGRD 223
ER DRE +R+++R+ R+R+ R+R+ EDR R+R+R+++RE++R RE R T +
Sbjct: 133 -ERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDME 191
Query: 224 RDKERDRERQREKDRDRQKAID 245
R+++R+ +R+R++ R+ ++ D
Sbjct: 192 RERQRETDRKRDRQRESERERD 213
Score = 173 bits (438), Expect = 2e-43
Identities = 93/196 (47%), Positives = 142/196 (72%), Gaps = 19/196 (9%)
Query: 59 ERERQRERE--RQRKRAKE-----RHREKDREIEKDRDRQRKRDRERQRWRDR--DRKRE 109
+R+R+R RE R+R RAKE RH E+DR+ +++R+R+R RDRER++ DR +R+RE
Sbjct: 18 DRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRE 77
Query: 110 RWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRE--REMG 167
R DRDR+ ETER+ ++ER+ DR E DRERQ+Q K+RE+E +DR+RE +EMG
Sbjct: 78 RERDRDRQRETERERDKERETDRHTETDRERQKQ------KEREMERVRDREREKQKEMG 131
Query: 168 ETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRE-RETGRDRDK 226
ER DRE +R+++R+ R+R+ R+R+ EDR R+R+R+++RE++R RE +E R D
Sbjct: 132 R-ERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDM 190
Query: 227 ERDRERQREKDRDRQK 242
ER+R+R+ ++ RDRQ+
Sbjct: 191 ERERQRETDRKRDRQR 206
Score = 155 bits (391), Expect = 5e-38
Identities = 82/180 (45%), Positives = 129/180 (71%), Gaps = 13/180 (7%)
Query: 72 RAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRE-RWGDRDRETETERQEERERQR 130
+ + RH + E DR R+R+R+ +R+R R ++ K E R +RDR+ + ER ER+R R
Sbjct: 4 KTEGRHTHTETET-MDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDR 62
Query: 131 DRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR--DRERERQKQRETRRD 188
+R+++ DRE +RQRE D+DR+ ETE++RD+ERE T+R+ DRER++QK+RE R
Sbjct: 63 EREKQTDREGERQRERERDRDRQRETERERDKERE---TDRHTETDRERQKQKEREMERV 119
Query: 189 RDRERQREKE---DRERDRDRQKEREKDRYRERETGRDR---DKERDRERQREKDRDRQK 242
RDRER+++KE +R+ DR+ +ERE+ RERETGR+R D+ R+RER+R+++R+R++
Sbjct: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
Score = 104 bits (260), Expect = 8e-23
Identities = 63/157 (40%), Positives = 93/157 (59%), Gaps = 29/157 (18%)
Query: 115 DRETETERQEERERQRDRKREK----DRERQRQREIGID---------KDREIETEKDRD 161
+ +TE DR+RE+ DRER R +E + +DRE E+DRD
Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
Query: 162 REREM---GETERYRDRERERQKQRETRRDR------------DRERQREKE-DRERDRD 205
RERE E ER R+RER+R +QRET R+R DRERQ++KE + ER RD
Sbjct: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
Query: 206 RQKEREKDRYRERETGRDRDKERDRERQREKDRDRQK 242
R++E++K+ RER+T R+ D+ER+R+ +RE++ R++
Sbjct: 122 REREKQKEMGRERQTDRETDRERERQAERERETGRER 158
Score = 84.7 bits (208), Expect = 8e-17
Identities = 46/94 (48%), Positives = 65/94 (69%), Gaps = 4/94 (4%)
Query: 155 ETEK-DRDREREMGETERYRDRERE-RQKQRETRRDRDRERQREKE-DRERDRDRQKERE 211
ETE DR RER ET+R RDR +E + + R + RDR R+R+R +E DR+R+R++Q +RE
Sbjct: 13 ETETMDRQRERRR-ETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDRE 71
Query: 212 KDRYRERETGRDRDKERDRERQREKDRDRQKAID 245
+R RERE RDR +E +RER +E++ DR D
Sbjct: 72 GERQRERERDRDRQRETERERDKERETDRHTETD 105
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 170 bits (430), Expect = 1e-42
Identities = 95/190 (50%), Positives = 138/190 (72%), Gaps = 20/190 (10%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
RER+RQRERE Q +R + RHR++DR E+DR R+++RERQ+ RDR R+RER + E
Sbjct: 19 RERDRQRERENQTER-ENRHRQRDRHRERDRQTDREKERERQKERDRQRQRER----ETE 73
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMG-----ETERY 172
ETERQ ER+RQR+RKR+ DRER + R D++R+ ET+++R+R R+ G +TER
Sbjct: 74 RETERQRERQRQRERKRQTDRERDKDR----DRERKRETDRNRERNRKGGRERDKQTERE 129
Query: 173 RDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRER 232
RDRERERQ+QRE R+R+RQRE++ RE DR+RQ+ E++ R++E ++R KER ++
Sbjct: 130 RDRERERQRQRE----RERQRQRERK-RETDRERQRWAEREE-RKKERKKERKKERKEKK 183
Query: 233 QREKDRDRQK 242
+ EK R+ +K
Sbjct: 184 KEEKRREDKK 193
Score = 166 bits (419), Expect = 3e-41
Identities = 99/206 (48%), Positives = 135/206 (65%), Gaps = 37/206 (17%)
Query: 61 ERQRERERQRKRAKERHREKDREIEKD-------RDRQRKRDRERQRWRDRDRKRERWGD 113
ERQRER+R+ R KE RE+DR+ E++ R RQR R RER R DR+++RER +
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 114 RDR--------ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRERE 165
RDR E ETERQ ER+RQR+RKR+ DRER + R D++R+ ET+++R+R R+
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDR----DRERKRETDRNRERNRK 117
Query: 166 MG-----ETERYRDRERERQKQRETRRDRDRERQREKEDRERDR-----DRQKEREKDRY 215
G +TER RDRERERQ+QRE R R RER+RE DRER R +R+KER+K+R
Sbjct: 118 GGRERDKQTERERDRERERQRQRERERQRQRERKRE-TDRERQRWAEREERKKERKKERK 176
Query: 216 RERETGRDRDKERDRERQREKDRDRQ 241
+ER KE+ +E +R +D+ R+
Sbjct: 177 KER-------KEKKKEEKRREDKKRK 195
Score = 147 bits (370), Expect = 1e-35
Identities = 73/159 (45%), Positives = 120/159 (75%), Gaps = 11/159 (6%)
Query: 84 IEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQ 143
+E+ R+R+R+ DR ++ R+RDR+RER E +TER E R RQRDR RE+DR+ R+
Sbjct: 1 MERQRERKRETDRGKETERERDRQRER------ENQTER-ENRHRQRDRHRERDRQTDRE 53
Query: 144 REIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERD 203
+E K+R+ + +++R+ ER ETER R+R+R+R+++R+T R+RD++R RE++ RE D
Sbjct: 54 KERERQKERDRQRQRERETER---ETERQRERQRQRERKRQTDRERDKDRDRERK-RETD 109
Query: 204 RDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQK 242
R+R++ R+ R R+++T R+RD+ER+R+RQRE++R RQ+
Sbjct: 110 RNRERNRKGGRERDKQTERERDRERERQRQRERERQRQR 148
Score = 125 bits (315), Expect = 3e-29
Identities = 64/142 (45%), Positives = 103/142 (72%), Gaps = 11/142 (7%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEK----DRDRQRKRDRERQRWRDRDRKRERWGD 113
+ER+RQR+RER+ +R ER RE+ R+ E+ DR+R + RDRER+R DR+R+R R G
Sbjct: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
Query: 114 RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173
R+R+ +TER+ +RER+R R+RE++R+RQR+R+ RE + E+ R ERE + ER +
Sbjct: 120 RERDKQTERERDRERERQRQRERERQRQRERK------RETDRERQRWAEREERKKERKK 173
Query: 174 DRERER-QKQRETRRDRDRERQ 194
+R++ER +K++E +R D++R+
Sbjct: 174 ERKKERKEKKKEEKRREDKKRK 195
Score = 110 bits (275), Expect = 1e-24
Identities = 60/130 (46%), Positives = 90/130 (69%), Gaps = 11/130 (8%)
Query: 121 ERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQ 180
ERQ ER+R+ DR +E +RER RQRE +RE + RDR RE RDR+ +R+
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERE-NRHRQRDRHRE-------RDRQTDRE 53
Query: 181 KQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDR 240
K+RE +++RDR+RQRE+E ER+ +RQ+ER++ R R+R+T R+RDK DR+R+R+++ DR
Sbjct: 54 KERERQKERDRQRQRERET-ERETERQRERQRQRERKRQTDRERDK--DRDRERKRETDR 110
Query: 241 QKAIDCVPGR 250
+ + GR
Sbjct: 111 NRERNRKGGR 120
Score = 95.1 bits (235), Expect = 6e-20
Identities = 52/134 (38%), Positives = 86/134 (64%), Gaps = 28/134 (20%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDR------------------ERQ 99
RE ER+ ER+R+R+R +ER R+ DRE +KDRDR+RKR+ ER+
Sbjct: 70 RETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERE 129
Query: 100 RWRDRDRKRERWGDRDRETETERQEERERQR-----DRKREKDRERQRQREIGIDKDREI 154
R R+R+R+R+R +R R+ E +R+ +RERQR +RK+E+ +ER+++R K+++
Sbjct: 130 RDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER-----KEKKK 184
Query: 155 ETEKDRDREREMGE 168
E ++ D++R+ GE
Sbjct: 185 EEKRREDKKRKWGE 198
Score = 94.7 bits (234), Expect = 8e-20
Identities = 52/101 (51%), Positives = 76/101 (75%), Gaps = 9/101 (8%)
Query: 154 IETEKDRDREREMG-ETERYRDRERERQKQ--RETR-RDRDRERQREKE-DRERDRDRQK 208
+E +++R RE + G ETER RDR+RER+ Q RE R R RDR R+R+++ DRE++R+RQK
Sbjct: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
Query: 209 EREKDRYRERETGRDRDKERDRERQREK----DRDRQKAID 245
ER++ R RERET R+ +++R+R+RQRE+ DR+R K D
Sbjct: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRD 101
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 166 bits (421), Expect = 2e-41
Identities = 88/184 (47%), Positives = 133/184 (72%), Gaps = 16/184 (8%)
Query: 59 ERERQRERER-QRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
ER+R+ RER QR + RH+ ++ E+E+D +R+ +R R DR +R R DR+RE
Sbjct: 628 ERDRRDNRERDQRPSSPIRHQGRNDELERD---ERREERRVDRVDDRRDERARERDRERE 684
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRER 177
+ ER+ ERER+RDR+REK+RE +R+R ++RE E EK+RDRER+ RDR+
Sbjct: 685 RDRERERERERERDREREKERELERERA----REREREREKERDRERD-------RDRDH 733
Query: 178 ERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQ-REK 236
+R+++RE RDR++ER+RE+E+RER+R+R++ERE++R RERE R+RDKER+R+R +K
Sbjct: 734 DRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDK 793
Query: 237 DRDR 240
D+ R
Sbjct: 794 DKGR 797
Score = 154 bits (390), Expect = 7e-38
Identities = 77/178 (43%), Positives = 123/178 (69%), Gaps = 6/178 (3%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
ER +R +R R ER RE+DRE ++RDR+R+R+RER+R R+R+++RE +R RE
Sbjct: 658 ERREERRVDRVDDRRDERARERDRE--RERDRERERERERERDREREKERELERERARER 715
Query: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERE 178
E ER++ER+R+RDR R+ DRER+R+RE +DRE E E++R+ E ER R+RERE
Sbjct: 716 EREREKERDRERDRDRDHDRERERERE----RDREKEREREREERERERERERERERERE 771
Query: 179 RQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREK 236
R+++R RD++RERQR+ ED+++ RD ++E+ ++ +R D+ + ++R R +
Sbjct: 772 RERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNE 829
Score = 146 bits (369), Expect = 2e-35
Identities = 81/203 (39%), Positives = 132/203 (65%), Gaps = 5/203 (2%)
Query: 40 EDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQ 99
E+R V + R A R+RER+R+RER+R+R +ER RE+++E E +R+R R+R+RER+
Sbjct: 661 EERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERERERE 720
Query: 100 RWRDRDRKRERWGDRDRETETERQEERERQR---DRKREKDRERQRQREIGIDKDREIET 156
+ RDR+R R+R DR+RE E ER E+ER+R +R+RE++RER+R+RE +++R E
Sbjct: 721 KERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARER 780
Query: 157 EKDRDREREMGETERYRDRERERQKQ-RETRRDRDRERQREKEDRERDRDRQKEREKDRY 215
+K+R+R+R+ + ++ RD RE++++ RE R RD +R+ + R R+ R+ +
Sbjct: 781 DKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPK- 839
Query: 216 RERETGRDRDKERDRERQREKDR 238
R RE D D + + EK R
Sbjct: 840 RRREHSPDSDAYNSGDDKNEKHR 862
Score = 127 bits (320), Expect = 9e-30
Identities = 76/191 (39%), Positives = 119/191 (62%), Gaps = 33/191 (17%)
Query: 59 ERERQRERERQRKRAKE-----RHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGD 113
ER+R ER+ R +A++ RH E+DR ++RD++ Q D + ER +
Sbjct: 604 ERDRYPERDN-RDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREE 662
Query: 114 RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173
R + +R++ER R+RDR+RE+DR E++R+RERE R
Sbjct: 663 RRVDRVDDRRDERARERDRERERDR------------------ERERERERE-------R 697
Query: 174 DRERERQKQRETRRDRDRERQREKE-DRERDRDRQKEREKDRYRERETGRDRDKER-DRE 231
DRERE++++ E R R+RER+REKE DRERDRDR +RE++R RER+ ++R++ER +RE
Sbjct: 698 DREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERE 757
Query: 232 RQREKDRDRQK 242
R+RE++R+R++
Sbjct: 758 RERERERERER 768
Score = 108 bits (270), Expect = 5e-24
Identities = 70/206 (33%), Positives = 103/206 (50%), Gaps = 21/206 (10%)
Query: 57 IRERERQRERERQRKRAKERHREKDREIEKDRDRQRK---------RDRERQRWRDRDR- 106
IR R R R R R + E+ + R + W R
Sbjct: 543 IRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSY 602
Query: 107 -KRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRERE 165
+R+R+ +RD + R +R R +RER QR + + E +RD RE
Sbjct: 603 PERDRYPERDNRDQARDSSFERRHGERDRRDNRERD-QRPSSPIRHQGRNDELERDERRE 661
Query: 166 MGETERYRDRERERQKQRETRRDRDRERQREKE---DRERDRDRQKEREKDRYRERETGR 222
+R DR ER ++R+ R+RDRER+RE+E DRER+++R+ ERE+ R RERE +
Sbjct: 662 ERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREK 721
Query: 223 DRDKER------DRERQREKDRDRQK 242
+RD+ER DRER+RE++RDR+K
Sbjct: 722 ERDRERDRDRDHDRERERERERDREK 747
Score = 97.4 bits (241), Expect = 1e-20
Identities = 58/206 (28%), Positives = 115/206 (55%), Gaps = 20/206 (9%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRER-WGDRDR 116
RERER+R+RE++R+R +E RE++RE E++R+R+R+R+RER R RD++R+R+R W D+D+
Sbjct: 737 RERERERDREKERERERE-ERERERERERERERERERERERARERDKERERQRDWEDKDK 795
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
+ R++ E + DR + ++ ++ ++ + + R +++ Y +
Sbjct: 796 GRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGD 855
Query: 177 RERQKQR---------ETRRDRDRERQREKEDRERDRDRQKEREKD--RYRERETGRDRD 225
+ +K R E+R +++ R ++ DR+ ER++ RY E+E ++
Sbjct: 856 DKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQEL---KE 912
Query: 226 KERDRERQREK----DRDRQKAIDCV 247
K ++QRE+ + R +A D +
Sbjct: 913 KVSSVDKQREQTEILESSRMRAQDII 938
Score = 81.3 bits (199), Expect = 9e-16
Identities = 55/177 (31%), Positives = 94/177 (53%), Gaps = 13/177 (7%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
E +RQ +++R +E+DR E DR+R+R+R RQR DRD ++ W R+R+
Sbjct: 1281 ESDRQVHSRSGSFDSRDRLQERDR-YEHDRERERERRDTRQREWDRDADKD-W-PRNRDR 1337
Query: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR----- 173
+ R+ ERER+RD++R+ DRER+R +++DR ++DRDR E + E +
Sbjct: 1338 DRLRERERERERDKRRDLDRERERLISDSVERDR----DRDRDRTFESSQIESVKRCEAK 1393
Query: 174 -DRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERD 229
+ E ER + +R +++R +D + ++ + +R E G D K D
Sbjct: 1394 LEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDESKLDD 1450
Score = 80.5 bits (197), Expect = 2e-15
Identities = 60/193 (31%), Positives = 94/193 (48%), Gaps = 37/193 (19%)
Query: 62 RQRERERQRKR---AKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
R + + RKR + R REK + +E +R+ + D+ ++ G+ R T
Sbjct: 1216 RSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKR------------GEPSRST 1263
Query: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERE 178
++RQ+ R R + + R D +DR +ER+ E +R R+RER
Sbjct: 1264 SSDRQDSRSHSSRRSSPESDRQVHSRSGSFDS-------RDRLQERDRYEHDRERERERR 1316
Query: 179 RQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRER------ 232
+QRE RD D++ R RDRDR +ERE RERE + RD +R+RER
Sbjct: 1317 DTRQREWDRDADKDWPRN-----RDRDRLRERE----RERERDKRRDLDRERERLISDSV 1367
Query: 233 QREKDRDRQKAID 245
+R++DRDR + +
Sbjct: 1368 ERDRDRDRDRTFE 1380
Score = 77.0 bits (188), Expect = 2e-14
Identities = 63/195 (32%), Positives = 94/195 (48%), Gaps = 21/195 (10%)
Query: 51 RVAPAIIRERERQRERE----RQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDR 106
RV + R+RE+ + E R+ + + + E R DR R R +
Sbjct: 1226 RVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQ 1285
Query: 107 KRERWGDRDRETETERQEERER-QRDRKREKDRERQRQREIGIDKDREIETEKDRDRERE 165
R G D +R +ER+R + DR+RE++R RQRE D D++ +DRDR RE
Sbjct: 1286 VHSRSGSFDSR---DRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRE 1342
Query: 166 MGETERYRDRERERQKQRE------TRRDRDRERQREKEDRERDRDRQKEREKDRYRERE 219
E ER RD+ R+ ++RE RDRDR+R R E + + ++ E + + ER+
Sbjct: 1343 R-ERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERD 1401
Query: 220 ---TGRDR---DKER 228
T RD DKER
Sbjct: 1402 LESTSRDSLALDKER 1416
Score = 69.3 bits (168), Expect = 4e-12
Identities = 45/184 (24%), Positives = 79/184 (42%), Gaps = 16/184 (8%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
+R++ R R R K RH + DR +R+ D +R R++D + ER ++D+ +
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSS 442
Query: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKD-----------REIETEKDRDREREMG 167
+ +++RE + R R R+ + +RE+ +D R+ + +D R
Sbjct: 443 SRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTR 502
Query: 168 ETERYRDRE-----RERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGR 222
+ YRDRE R+ E R R RE+ R R+ + + R GR
Sbjct: 503 DAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGR 562
Query: 223 DRDK 226
R +
Sbjct: 563 SRGR 566
Score = 67.4 bits (163), Expect = 1e-11
Identities = 51/172 (29%), Positives = 79/172 (45%), Gaps = 17/172 (9%)
Query: 69 QRKRAKERHREKDREIEK-DRDR-QRKRDRERQRWRDRDRKRERWGDRDRETETERQEER 126
QRK++ RHR RE + D +R + DR +R D KR+R E + +EER
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDR--------EKDSREER 434
Query: 127 ERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETR 186
E ++D+ +D R+ G D+ R+ +DR RE+ ++ RD R R+T+
Sbjct: 435 EYEQDQSSSRDHRDDREPRDGRDR-RDARDTRDR---RELRDSRDMRDSREMRDYSRDTK 490
Query: 187 RDRDRERQREKEDRERDRDRQ---KEREKDRYRERETGRDRDKERDRERQRE 235
RD R D RDR+ R++D Y E R+ R+ + E
Sbjct: 491 ESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTE 542
Score = 66.6 bits (161), Expect = 2e-11
Identities = 72/289 (24%), Positives = 115/289 (39%), Gaps = 105/289 (36%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKD----------RDRQRKRD-RERQRWRD--- 103
R + + +R+R++ +ER E+D+ +D RDR+ RD R+R+ RD
Sbjct: 416 RREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRD 475
Query: 104 -----------RDRKRERWGDRDRETETERQEERERQ-RDRKREKDRERQRQREIGIDKD 151
RD K R RD + + + R+R+ RD R++D + R G +
Sbjct: 476 MRDSREMRDYSRDTKESR-DPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHL 534
Query: 152 REIETEKD-RDREREMGETERYRDR----------------------------------- 175
RE + + R+ R +E DR
Sbjct: 535 REESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHD 594
Query: 176 ---------ERERQKQRETR---RDRDRERQREKEDRERDRDR----------------- 206
ER+R +R+ R RD ER+ + DR +R+R
Sbjct: 595 SWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDEL 654
Query: 207 -----QKEREKDRY--------RERETGRDRDKERDRERQREKDRDRQK 242
++ER DR RER+ R+RD+ER+RER+RE+DR+R+K
Sbjct: 655 ERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREK 703
Score = 61.2 bits (147), Expect = 1e-09
Identities = 66/221 (29%), Positives = 93/221 (42%), Gaps = 50/221 (22%)
Query: 71 KRAKERHREKDREIEKDRD-RQRKRDRERQRW-RDRDRKRERWGDR-----DRETETERQ 123
K+ KE+++ KDR EK RD + R RD ERQR RD+ R G R + Q
Sbjct: 278 KKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQ 337
Query: 124 EERERQRD-----RKREKDRERQR---------------------QREIGIDKDREIETE 157
QR RKR QR QR+ + R E
Sbjct: 338 SGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMRE 397
Query: 158 KDR-DREREMGETERYRDRERERQKQRETRRDRDRERQREKE---DRERDRDRQKEREKD 213
K R D ER T + DR ER++ +RDR+++ + E+E D+ RD + +RE
Sbjct: 398 KGRHDHER----TSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPR 453
Query: 214 RYRERETGRD-RDKE--------RDRERQREKDRDRQKAID 245
R+R RD RD+ RD R+ RD +++ D
Sbjct: 454 DGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRD 494
Score = 58.9 bits (141), Expect = 5e-09
Identities = 62/259 (23%), Positives = 100/259 (38%), Gaps = 83/259 (32%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRD----------RQRKRDRERQRWRDRD-- 105
RERER+RERER+R+R +ER RE+D+E E+ RD R+ KR+ R+ RD
Sbjct: 758 RERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGH 817
Query: 106 ----------------------RKRERWGDRDRETE------------------------ 119
R+RE D D
Sbjct: 818 DERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLS 877
Query: 120 ----TERQEERERQRDRKREKDRERQRQRE-------IGIDKDREIETEKDRDREREMGE 168
TE ++ R ++ DRK E+ +R E +DK RE + E+ E
Sbjct: 878 PSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQRE---------QTEILE 928
Query: 169 TERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKD-----RYRERETGRD 223
+ R R ++ Q E R DR K+ + + K++++D R T D
Sbjct: 929 SSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSED 988
Query: 224 RDKERDRERQREKDRDRQK 242
++ Q++K ++++
Sbjct: 989 GQVFSPKKGQKKKSIEKKR 1007
Score = 53.5 bits (127), Expect = 2e-07
Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 3/135 (2%)
Query: 116 RETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDR 175
R R++ R + DR +R+ + +DRE ++ ++R+ E++ + +RD
Sbjct: 390 RHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRD- 448
Query: 176 ERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDR-YRERETGRDRDKERDRERQR 234
+RE + R+ R RD +RE D RD ++ R+ R +E RD RD R
Sbjct: 449 DREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYR 508
Query: 235 EKD-RDRQKAIDCVP 248
+++ RD + D P
Sbjct: 509 DREGRDTHRKEDTYP 523
Score = 49.3 bits (116), Expect = 4e-06
Identities = 45/154 (29%), Positives = 64/154 (41%), Gaps = 28/154 (18%)
Query: 91 QRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDK 150
QRK+ R R R++ R D +R T ER+ D + ++DRE
Sbjct: 383 QRKQSPPRHRSPMREKGRH---DHER-TSQSHDRRHERREDTRGKRDRE----------- 427
Query: 151 DREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKER 210
KD ERE E+ + R+ + RE R RDR R+ DR RD + R
Sbjct: 428 -------KDSREEREY---EQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMR 477
Query: 211 EKDRYRE--RETGRDRDKERDRERQREKD-RDRQ 241
+ R+ R+T RD R + D RDR+
Sbjct: 478 DSREMRDYSRDTKESRDPRDSRSTRDAHDYRDRE 511
Score = 38.5 bits (88), Expect = 0.007
Identities = 47/215 (21%), Positives = 92/215 (42%), Gaps = 29/215 (13%)
Query: 58 RERERQRERERQRKRAKERH-REKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
+E +R+ ER+ +R +E+ +EK ++K R++ + R R +D + DR
Sbjct: 890 KEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQ---SEDR 946
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
ET DR ++++++ + ++ I K +E + +R E D +
Sbjct: 947 ETS-----------DRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSE-----DGQ 990
Query: 177 RERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREK 236
K+ + ++ +++R++ K D + D + ++ + R T KE E K
Sbjct: 991 VFSPKKGQKKKSIEKKRKKSKGDSDIS-DEEAAQQSKKKRGPRTPPITTKEELVEMCNGK 1049
Query: 237 D---RDRQKAIDCVPGRWEVTVMAVDCVPGRWEVT 268
+ D QK D W + + VP R EVT
Sbjct: 1050 NGILEDSQKKEDTAFSDW-----SDEDVPDRTEVT 1079
Score = 35.4 bits (80), Expect = 0.058
Identities = 51/243 (20%), Positives = 97/243 (39%), Gaps = 61/243 (25%)
Query: 60 RERQRERERQRKRAKERHREKDREIEKDRDRQRKRD--RERQRWRDRDRK-----RERWG 112
R +R R+R K + ++ D E +K + +E R R R+++ +ER
Sbjct: 76 RSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTP 135
Query: 113 DRDRET---ETERQEE----------RERQRDRKREK-DRERQRQREIGIDKDREIETEK 158
+ + E ET R + E + KR+K RE + + ++K EI +K
Sbjct: 136 ESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKK 195
Query: 159 DRDRE------------REMGETERYRDRERERQKQRETRR---------DRDRERQREK 197
+ E R+ ++ + + + ++ R+ D+ R + +
Sbjct: 196 EVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQ 255
Query: 198 EDRERDRD-----------------RQKEREKDRYRERETGRDRDKERDRERQREKDRDR 240
++ R ++K + KDR E+ T +D+ RD ERQREK RD+
Sbjct: 256 SKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEK-TRDGKDRGRDFERQREK-RDK 313
Query: 241 QKA 243
++
Sbjct: 314 PRS 316
Score = 34.7 bits (78), Expect = 0.098
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 10/100 (10%)
Query: 130 RDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDR 189
R + + R +R G ++R +D D E + TE + R++
Sbjct: 66 RGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTE---------ESSSPVRKES 116
Query: 190 DRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERD 229
R R REKED + ++R E E++ E ET RD D
Sbjct: 117 SRGRHREKEDIKITKERTPESEEENV-EWETNRDDSDNGD 155
Score = 33.5 bits (75), Expect = 0.22
Identities = 33/126 (26%), Positives = 49/126 (38%), Gaps = 19/126 (15%)
Query: 93 KRDRERQRWRDRDRKRERWGDRDRETETERQEE------RERQRDRKREKDRERQRQREI 146
+R ER R+R + + D D E + EE +E R R REK+
Sbjct: 75 RRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKE--------- 125
Query: 147 GIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDR 206
D +I E+ + E E E E RD + + E +R+K RE +
Sbjct: 126 ----DIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLE 181
Query: 207 QKEREK 212
Q+ EK
Sbjct: 182 QENMEK 187
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 160 bits (406), Expect = 9e-40
Identities = 88/198 (44%), Positives = 136/198 (68%), Gaps = 8/198 (4%)
Query: 56 IIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRD 115
I RE + R+ ++ + K + ++ +EIEK+R R+R+R+RER+R R R+R+RER +R+
Sbjct: 277 ISREISKFRDTHKKLEEEKGKKEKERQEIEKER-RERERERERERER-RERERERERERE 334
Query: 116 RETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDR 175
RE E ER+ ERER RDR R K+R+R R RE D+DRE +++++DR R E+ RDR
Sbjct: 335 REKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSR---SREKSRDR 391
Query: 176 ERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQRE 235
ERER+++RE R+R+RER+RE+E RER+R+R++EREKD+ R+RE D + +R +
Sbjct: 392 ERERERERERERERERERERERE-REREREREREREKDKKRDRE--EDEEDAYERRKLER 448
Query: 236 KDRDRQKAIDCVPGRWEV 253
K R+++ A WE+
Sbjct: 449 KLREKEAAYQERLKNWEI 466
Score = 160 bits (406), Expect = 9e-40
Identities = 87/191 (45%), Positives = 137/191 (71%), Gaps = 19/191 (9%)
Query: 58 RERERQRERERQRK-RAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
RERER+RERER+R+ R +ER RE++RE EK+R+R+R+RDR+R R ++RDR R+R +RDR
Sbjct: 310 RERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDR--ERDR 367
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
+ + ER +R + R R REK R+R+R+RE ++RE E E++R+RERE R+RE
Sbjct: 368 DRDRERSSDRNKDRSRSREKSRDRERERE----RERERERERERERERE-------RERE 416
Query: 177 RERQKQRETRRDRDRERQREKEDR-ERDRDRQKEREKD-RYRERETG---RDRDKERDRE 231
RER+++RE +D+ R+R+ ++ED ER + +K REK+ Y+ER R+R K R+ E
Sbjct: 417 REREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYE 476
Query: 232 RQREKDRDRQK 242
++ E++ +R++
Sbjct: 477 KEAEREEERRR 487
Score = 158 bits (400), Expect = 5e-39
Identities = 82/188 (43%), Positives = 132/188 (70%), Gaps = 11/188 (5%)
Query: 58 RERERQRERER-QRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
RERER+RERER +R+R +ER RE+++E E++R+R+R RDR+R + RDRDR RER DRDR
Sbjct: 312 RERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDR 371
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
E ++R ++R R R++ R+++RER+R+RE ++RE E E++R+RER E ER R+RE
Sbjct: 372 ERSSDRNKDRSRSREKSRDRERERERERE----RERERERERERERER---ERERERERE 424
Query: 177 RERQKQRETRRDRD---RERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQ 233
RE+ K+R+ D + R+ E++ RE++ Q+ + RER+ R+ +KE +RE +
Sbjct: 425 REKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEE 484
Query: 234 REKDRDRQ 241
R ++ ++
Sbjct: 485 RRREMAKE 492
Score = 157 bits (396), Expect = 1e-38
Identities = 81/191 (42%), Positives = 128/191 (67%), Gaps = 8/191 (4%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRD-- 115
RERER+RERER+R++ KER RE++R ++DRDR ++RDR+R R RDRDR RER DR+
Sbjct: 323 REREREREREREREKEKERERERER--DRDRDRTKERDRDRDRERDRDRDRERSSDRNKD 380
Query: 116 ----RETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETER 171
RE +R+ ERER+R+R+RE++RER+R+RE +++RE E EKD+ R+RE E +
Sbjct: 381 RSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDA 440
Query: 172 YRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRE 231
Y R+ ER+ + + ++R + E +R++ R+ +KE E++ R RE ++ + ++
Sbjct: 441 YERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFL 500
Query: 232 RQREKDRDRQK 242
+ DRD K
Sbjct: 501 EDYDDDRDDPK 511
Score = 154 bits (390), Expect = 7e-38
Identities = 81/190 (42%), Positives = 133/190 (70%), Gaps = 12/190 (6%)
Query: 55 AIIRERERQRERERQRKRAKERHREKDREI-EKDRDRQRKRDRERQRWRDRDRKRERWGD 113
AI E +++ R+ + ++ H++ + E +K+++RQ R+R R+R+R+RER +
Sbjct: 266 AIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERER-RE 324
Query: 114 RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173
R+RE E ER+ E+E++R+R+RE+DR+R R +E +DR+ + E+DRDR+R ER
Sbjct: 325 REREREREREREKEKERERERERDRDRDRTKE----RDRDRDRERDRDRDR-----ERSS 375
Query: 174 DRERERQKQRETRRDRDRERQREKE-DRERDRDRQKEREKDRYRERETGRDRDKERDRER 232
DR ++R + RE RDR+RER+RE+E +RER+R+R++ERE++R RERE R++DK+RDRE
Sbjct: 376 DRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREE 435
Query: 233 QREKDRDRQK 242
E +R+K
Sbjct: 436 DEEDAYERRK 445
Score = 141 bits (355), Expect = 7e-34
Identities = 82/203 (40%), Positives = 127/203 (62%), Gaps = 23/203 (11%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRK----RDRERQRWRDRDRKRERWGD 113
+ERER+RER+R R R KER R++DRE ++DRDR+R +DR R R + RDR+RER +
Sbjct: 339 KERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERE 398
Query: 114 RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEK----DRDREREMGET 169
R+RE E ER+ ERER+R+R+RE++RER++ ++ ++D E E+ + RE+E
Sbjct: 399 REREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQ 458
Query: 170 ERYRDRE-RERQKQRETRRDRDRERQREK-------------EDRERDRDRQKEREKDRY 215
ER ++ E RER+K RE ++ +RE +R + ED + DRD K
Sbjct: 459 ERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSAL 518
Query: 216 RERETGRDRDKERD-RERQREKD 237
++R R+++ E D R+R+REK+
Sbjct: 519 QKRLRDREKEMEADERDRKREKE 541
Score = 115 bits (287), Expect = 6e-26
Identities = 72/217 (33%), Positives = 123/217 (56%), Gaps = 32/217 (14%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDR----ERQRWRDRDRKRE---- 109
RERER+RERER+R+R +ER RE++RE EKD+ R R+ D ER++ + R++E
Sbjct: 399 REREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQ 458
Query: 110 ----RWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKD------ 159
W R+R+ E ++E ER+ +R+RE +E +R +E D D + + K
Sbjct: 459 ERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSAL 518
Query: 160 ----RDREREMGETERYRDRERERQKQRETRR--------DRDRERQREKEDRERDRDRQ 207
RDRE+EM E RDR+RE+++ E R+ D D E QR +++ ER R Q
Sbjct: 519 QKRLRDREKEMEADE--RDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQ 576
Query: 208 KEREKDRYRERETGRDRDKERDRERQREKDRDRQKAI 244
++E + E E ++++++R+ + E++ +++ +
Sbjct: 577 IKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCL 613
Score = 94.4 bits (233), Expect = 1e-19
Identities = 54/149 (36%), Positives = 90/149 (60%), Gaps = 21/149 (14%)
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIG-------IDKD--REIETEKDRDREREMG 167
E QE R +K+EK + R+ + I K+ IE E+D+ R+
Sbjct: 221 ELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDK-RDLISR 279
Query: 168 ETERYRD-----------RERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYR 216
E ++RD +E+ERQ+ + RR+R+RER+RE+E RER+R+R++ERE+++ +
Sbjct: 280 EISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEK 339
Query: 217 ERETGRDRDKERDRERQREKDRDRQKAID 245
ERE R+RD++RDR ++R++DRDR++ D
Sbjct: 340 ERERERERDRDRDRTKERDRDRDRERDRD 368
Score = 66.2 bits (160), Expect = 3e-11
Identities = 47/160 (29%), Positives = 85/160 (53%), Gaps = 20/160 (12%)
Query: 57 IRERERQRERERQRKRAKERHREKDREIEKDRD--RQRKRDRERQRWRDRDRKRERWGDR 114
IRER++ RE E++ +R +ER RE +E ++ ++ DR+ ++ ++R DR
Sbjct: 466 IRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDR 525
Query: 115 DRETETERQEERERQRDRKREKDR-ERQRQREIGIDKDREIETEKDRDREREMGETERYR 173
++E E + +RDRKREK+ E RQR + E D + E+ E+
Sbjct: 526 EKEMEAD-------ERDRKREKEELEEIRQR---------LLAEGHPDPDAELQRMEQEA 569
Query: 174 DRERERQKQRETRRDRDRERQREKED-RERDRDRQKEREK 212
+R R+ Q ++E + + E ++EKE+ RE + ++E E+
Sbjct: 570 ERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQ 609
Score = 44.7 bits (104), Expect = 9e-05
Identities = 37/113 (32%), Positives = 60/113 (53%), Gaps = 16/113 (14%)
Query: 40 EDRD-VLILRGSRVAPAIIRERERQRER-ERQRKRAKERHREKDREIEKDRDR-----QR 92
+DRD RGS + + R+RE++ E ER RKR KE E+E+ R R
Sbjct: 505 DDRDDPKYYRGSALQKRL-RDREKEMEADERDRKREKE-------ELEEIRQRLLAEGHP 556
Query: 93 KRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQRE 145
D E QR +++ +R R +E E+E +EE +++++ KRE+ E + + E
Sbjct: 557 DPDAELQR-MEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPE 608
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 130 bits (327), Expect = 1e-30
Identities = 68/192 (35%), Positives = 123/192 (64%), Gaps = 21/192 (10%)
Query: 60 RERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGD-RDRET 118
R+R + + R R + R R+KDR K ++R + RER++ R R R++ D R++
Sbjct: 326 RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIK 385
Query: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERE 178
E ER +E++R+++R+REK+RE++++R G +KDR+ E EKDR++++E +DRERE
Sbjct: 386 EKERVKEKDREKEREREKEREKEKER--GKNKDRDKEREKDREKDKE-------KDRERE 436
Query: 179 RQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERE----------TGRDRDKER 228
R+K+ E RD+++E++++KE +ER++DR KE ++ R ++++ + R R R
Sbjct: 437 REKEHEKDRDKEKEKEQDKE-KEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSR 495
Query: 229 DRERQREKDRDR 240
+R R+R + R
Sbjct: 496 ERRRRRSRSSSR 507
Score = 128 bits (321), Expect = 7e-30
Identities = 69/187 (36%), Positives = 113/187 (60%), Gaps = 6/187 (3%)
Query: 52 VAPAIIRERERQRERERQRKRAKERHREKDREIEK-DRDRQRKRDRERQRWRDRDRKRER 110
+ P + ER+ R R R+K R K K + + R R R R R +DR+R +
Sbjct: 293 IEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSK 352
Query: 111 WGDRDRETETERQEERERQRDRKREKD-RERQRQREIGIDKDREIETEKDRDREREMGET 169
+ R ER++ R R R + KD RE+ +++E +KDRE E E++++RE+E E
Sbjct: 353 SPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEK-ER 411
Query: 170 ERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERD 229
+ +DR++ER+K RE +++DRER+REKE ++DR KE+EK++ +E+E +DR KE D
Sbjct: 412 GKNKDRDKEREKDREKDKEKDREREREKE---HEKDRDKEKEKEQDKEKEREKDRSKEID 468
Query: 230 RERQREK 236
+R+++K
Sbjct: 469 EKRKKDK 475
Score = 127 bits (319), Expect = 1e-29
Identities = 70/189 (37%), Positives = 116/189 (61%), Gaps = 14/189 (7%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
E E + ER+ R++ R K R K R RKR + + R R +R R R DR R
Sbjct: 294 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSR-RKRSQSKHRSRSHNRSRSRQKDRRRSK 352
Query: 119 ET--ERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
+R + RER++ R R R++++ I K++E EKDR++ERE R++E
Sbjct: 353 SPHKKRSKSRERRKSRSRSHSRDKRKDTREKI-KEKERVKEKDREKERE-------REKE 404
Query: 177 RERQKQRETRRDRDRERQREKE---DRERDRDRQKEREKDRYRERETGRDRDKERDRERQ 233
RE++K+R +DRD+ER++++E +++R+R+R+KE EKDR +E+E +D++KER+++R
Sbjct: 405 REKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRS 464
Query: 234 REKDRDRQK 242
+E D R+K
Sbjct: 465 KEIDEKRKK 473
Score = 119 bits (299), Expect = 2e-27
Identities = 62/204 (30%), Positives = 116/204 (56%), Gaps = 9/204 (4%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQ---RKRDRERQRWRDRDRKRERWGDR 114
R+++R+R + +KR+K R R K R RD++ R++ +E++R +++DR++ER ++
Sbjct: 344 RQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREK 403
Query: 115 DRETETER------QEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGE 168
+RE E ER +ERE+ R++ +EKDRER+R++E D+D+E E E+D+++ERE
Sbjct: 404 EREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDR 463
Query: 169 TERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKER 228
++ ++ ++ +K R R + R+ RER R R + + + R +
Sbjct: 464 SKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSP 523
Query: 229 DRERQREKDRDRQKAIDCVPGRWE 252
+ +KD+ R+K D + R E
Sbjct: 524 SPRSRNKKDKKREKERDHISERRE 547
Score = 118 bits (295), Expect = 7e-27
Identities = 65/212 (30%), Positives = 126/212 (59%), Gaps = 29/212 (13%)
Query: 58 RERERQRERE---------RQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKR 108
RER + R R R++ + KER +EKDRE E++R+++R++++ER + +DRD++R
Sbjct: 362 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 421
Query: 109 ERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRE----- 163
E+ ++D+E + ER+ E+E ++DR +EK++E+ +++E D+ +EI+ ++ +D++
Sbjct: 422 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 481
Query: 164 REMGETERYRDRERERQKQRETRRDRD--------RERQREKEDRERD-RDRQKEREKDR 214
R + R R RER+++R R R+ R R R+ +D+++E+E+D
Sbjct: 482 RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDH 541
Query: 215 YRERETGRDRDKERDRE-RQREKDRDRQKAID 245
ER R++ER R+ DRD ++ ++
Sbjct: 542 ISER-----RERERSTSMRKSSNDRDGKEKLE 568
Score = 107 bits (268), Expect = 9e-24
Identities = 57/191 (29%), Positives = 102/191 (53%), Gaps = 4/191 (2%)
Query: 52 VAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERW 111
V P + + +E E KR +E IE + + +R R R R + R
Sbjct: 261 VKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSS 320
Query: 112 GDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETER 171
R +R + + R R R + R++ R+R K R E+ + R R +R
Sbjct: 321 KSHSRR---KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKR 377
Query: 172 YRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRE 231
RE+ ++K+R +DR++ER+REKE RE++++R K +++D+ RE++ +D++K+R+RE
Sbjct: 378 KDTREKIKEKERVKEKDREKEREREKE-REKEKERGKNKDRDKEREKDREKDKEKDRERE 436
Query: 232 RQREKDRDRQK 242
R++E ++DR K
Sbjct: 437 REKEHEKDRDK 447
Score = 105 bits (262), Expect = 5e-23
Identities = 55/199 (27%), Positives = 114/199 (57%), Gaps = 17/199 (8%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
RE+ER++E+ER + + +++ REKDRE +K++DR+R+R++E ++ RD+++++E+ +++RE
Sbjct: 401 REKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKERE 460
Query: 118 TETERQEERERQRDRK------------REKDRERQRQREIGIDKDREIETEKDRDRERE 165
+ ++ + +R++D+K R + R+R+R R T K R+
Sbjct: 461 KDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSS 520
Query: 166 MGETERYRD-RERERQKQRE---TRRDRDRERQREKEDRERDRDRQKEREKDRYRERETG 221
+ R R+ ++++R+K+R+ RR+R+R K +RD + E+ +E+E
Sbjct: 521 RSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHN 580
Query: 222 RDRDKERDRERQREKDRDR 240
++ D +E +KD R
Sbjct: 581 KEPDSSVSKEVD-DKDAPR 598
Score = 58.5 bits (140), Expect = 6e-09
Identities = 46/188 (24%), Positives = 84/188 (44%), Gaps = 53/188 (28%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDR----DRQRKRD--------------RERQ 99
RERER++E E+ R + KE+ ++K++E EKDR D +RK+D R R
Sbjct: 433 REREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRS 492
Query: 100 RWRDRDRKRERWGDRDRET------------------ETERQEERERQRDRKREKDRERQ 141
R+R R+R R R T + +++ E+ER +R R+
Sbjct: 493 SSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER-----RE 547
Query: 142 RQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRE 201
R+R + K + DRD + ++ ++ K++E ++ D +E +D++
Sbjct: 548 RERSTSMRK-----SSNDRDGKEKL-------EKNSTSLKEKEHNKEPDSSVSKEVDDKD 595
Query: 202 RDRDRQKE 209
R + +
Sbjct: 596 APRTEENK 603
Score = 48.1 bits (113), Expect = 9e-06
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 2/131 (1%)
Query: 50 SRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRE 109
SR P R R R+R+R + R + K R+ R + +D+KRE
Sbjct: 477 SRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKRE 536
Query: 110 RWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGET 169
+ +RD +E +E R ++D + + ++ K++E E D +E+ +
Sbjct: 537 K--ERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK 594
Query: 170 ERYRDRERERQ 180
+ R E + Q
Sbjct: 595 DAPRTEENKIQ 605
Score = 34.3 bits (77), Expect = 0.13
Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 9/129 (6%)
Query: 25 QTRPVSWRLAMRSQIEDRDVL------ILRGSRVAPAIIRERERQRERERQRKRAKERHR 78
+T P S+ + RS+ R+ R R + I R+ R + K+ K+R +
Sbjct: 478 RTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 537
Query: 79 EKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRK-REKD 137
E+D I + R+R+R R+ DRD K + + E E +E + ++ +KD
Sbjct: 538 ERD-HISERRERERSTSM-RKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKD 595
Query: 138 RERQRQREI 146
R + +I
Sbjct: 596 APRTEENKI 604
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 130 bits (327), Expect = 1e-30
Identities = 68/192 (35%), Positives = 123/192 (64%), Gaps = 21/192 (10%)
Query: 60 RERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGD-RDRET 118
R+R + + R R + R R+KDR K ++R + RER++ R R R++ D R++
Sbjct: 210 RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIK 269
Query: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERE 178
E ER +E++R+++R+REK+RE++++R G +KDR+ E EKDR++++E +DRERE
Sbjct: 270 EKERVKEKDREKEREREKEREKEKER--GKNKDRDKEREKDREKDKE-------KDRERE 320
Query: 179 RQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERE----------TGRDRDKER 228
R+K+ E RD+++E++++KE +ER++DR KE ++ R ++++ + R R R
Sbjct: 321 REKEHEKDRDKEKEKEQDKE-KEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSR 379
Query: 229 DRERQREKDRDR 240
+R R+R + R
Sbjct: 380 ERRRRRSRSSSR 391
Score = 128 bits (321), Expect = 7e-30
Identities = 69/187 (36%), Positives = 113/187 (60%), Gaps = 6/187 (3%)
Query: 52 VAPAIIRERERQRERERQRKRAKERHREKDREIEK-DRDRQRKRDRERQRWRDRDRKRER 110
+ P + ER+ R R R+K R K K + + R R R R R +DR+R +
Sbjct: 177 IEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSK 236
Query: 111 WGDRDRETETERQEERERQRDRKREKD-RERQRQREIGIDKDREIETEKDRDREREMGET 169
+ R ER++ R R R + KD RE+ +++E +KDRE E E++++RE+E E
Sbjct: 237 SPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEK-ER 295
Query: 170 ERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERD 229
+ +DR++ER+K RE +++DRER+REKE ++DR KE+EK++ +E+E +DR KE D
Sbjct: 296 GKNKDRDKEREKDREKDKEKDREREREKE---HEKDRDKEKEKEQDKEKEREKDRSKEID 352
Query: 230 RERQREK 236
+R+++K
Sbjct: 353 EKRKKDK 359
Score = 127 bits (319), Expect = 1e-29
Identities = 70/189 (37%), Positives = 116/189 (61%), Gaps = 14/189 (7%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
E E + ER+ R++ R K R K R RKR + + R R +R R R DR R
Sbjct: 178 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSR-RKRSQSKHRSRSHNRSRSRQKDRRRSK 236
Query: 119 ET--ERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
+R + RER++ R R R++++ I K++E EKDR++ERE R++E
Sbjct: 237 SPHKKRSKSRERRKSRSRSHSRDKRKDTREKI-KEKERVKEKDREKERE-------REKE 288
Query: 177 RERQKQRETRRDRDRERQREKE---DRERDRDRQKEREKDRYRERETGRDRDKERDRERQ 233
RE++K+R +DRD+ER++++E +++R+R+R+KE EKDR +E+E +D++KER+++R
Sbjct: 289 REKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRS 348
Query: 234 REKDRDRQK 242
+E D R+K
Sbjct: 349 KEIDEKRKK 357
Score = 119 bits (299), Expect = 2e-27
Identities = 62/204 (30%), Positives = 116/204 (56%), Gaps = 9/204 (4%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQ---RKRDRERQRWRDRDRKRERWGDR 114
R+++R+R + +KR+K R R K R RD++ R++ +E++R +++DR++ER ++
Sbjct: 228 RQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREK 287
Query: 115 DRETETER------QEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGE 168
+RE E ER +ERE+ R++ +EKDRER+R++E D+D+E E E+D+++ERE
Sbjct: 288 EREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDR 347
Query: 169 TERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKER 228
++ ++ ++ +K R R + R+ RER R R + + + R +
Sbjct: 348 SKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSP 407
Query: 229 DRERQREKDRDRQKAIDCVPGRWE 252
+ +KD+ R+K D + R E
Sbjct: 408 SPRSRNKKDKKREKERDHISERRE 431
Score = 118 bits (295), Expect = 7e-27
Identities = 65/212 (30%), Positives = 126/212 (59%), Gaps = 29/212 (13%)
Query: 58 RERERQRERE---------RQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKR 108
RER + R R R++ + KER +EKDRE E++R+++R++++ER + +DRD++R
Sbjct: 246 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 305
Query: 109 ERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRE----- 163
E+ ++D+E + ER+ E+E ++DR +EK++E+ +++E D+ +EI+ ++ +D++
Sbjct: 306 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 365
Query: 164 REMGETERYRDRERERQKQRETRRDRD--------RERQREKEDRERD-RDRQKEREKDR 214
R + R R RER+++R R R+ R R R+ +D+++E+E+D
Sbjct: 366 RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDH 425
Query: 215 YRERETGRDRDKERDRE-RQREKDRDRQKAID 245
ER R++ER R+ DRD ++ ++
Sbjct: 426 ISER-----RERERSTSMRKSSNDRDGKEKLE 452
Score = 107 bits (268), Expect = 9e-24
Identities = 57/191 (29%), Positives = 102/191 (53%), Gaps = 4/191 (2%)
Query: 52 VAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERW 111
V P + + +E E KR +E IE + + +R R R R + R
Sbjct: 145 VKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSS 204
Query: 112 GDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETER 171
R +R + + R R R + R++ R+R K R E+ + R R +R
Sbjct: 205 KSHSRR---KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKR 261
Query: 172 YRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRE 231
RE+ ++K+R +DR++ER+REKE RE++++R K +++D+ RE++ +D++K+R+RE
Sbjct: 262 KDTREKIKEKERVKEKDREKEREREKE-REKEKERGKNKDRDKEREKDREKDKEKDRERE 320
Query: 232 RQREKDRDRQK 242
R++E ++DR K
Sbjct: 321 REKEHEKDRDK 331
Score = 105 bits (262), Expect = 5e-23
Identities = 55/199 (27%), Positives = 114/199 (57%), Gaps = 17/199 (8%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
RE+ER++E+ER + + +++ REKDRE +K++DR+R+R++E ++ RD+++++E+ +++RE
Sbjct: 285 REKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKERE 344
Query: 118 TETERQEERERQRDRK------------REKDRERQRQREIGIDKDREIETEKDRDRERE 165
+ ++ + +R++D+K R + R+R+R R T K R+
Sbjct: 345 KDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSS 404
Query: 166 MGETERYRD-RERERQKQRE---TRRDRDRERQREKEDRERDRDRQKEREKDRYRERETG 221
+ R R+ ++++R+K+R+ RR+R+R K +RD + E+ +E+E
Sbjct: 405 RSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHN 464
Query: 222 RDRDKERDRERQREKDRDR 240
++ D +E +KD R
Sbjct: 465 KEPDSSVSKEVD-DKDAPR 482
Score = 58.5 bits (140), Expect = 6e-09
Identities = 46/188 (24%), Positives = 84/188 (44%), Gaps = 53/188 (28%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDR----DRQRKRD--------------RERQ 99
RERER++E E+ R + KE+ ++K++E EKDR D +RK+D R R
Sbjct: 317 REREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRS 376
Query: 100 RWRDRDRKRERWGDRDRET------------------ETERQEERERQRDRKREKDRERQ 141
R+R R+R R R T + +++ E+ER +R R+
Sbjct: 377 SSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER-----RE 431
Query: 142 RQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRE 201
R+R + K + DRD + ++ ++ K++E ++ D +E +D++
Sbjct: 432 RERSTSMRK-----SSNDRDGKEKL-------EKNSTSLKEKEHNKEPDSSVSKEVDDKD 479
Query: 202 RDRDRQKE 209
R + +
Sbjct: 480 APRTEENK 487
Score = 48.1 bits (113), Expect = 9e-06
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 2/131 (1%)
Query: 50 SRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRE 109
SR P R R R+R+R + R + K R+ R + +D+KRE
Sbjct: 361 SRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKRE 420
Query: 110 RWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGET 169
+ +RD +E +E R ++D + + ++ K++E E D +E+ +
Sbjct: 421 K--ERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK 478
Query: 170 ERYRDRERERQ 180
+ R E + Q
Sbjct: 479 DAPRTEENKIQ 489
Score = 34.3 bits (77), Expect = 0.13
Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 9/129 (6%)
Query: 25 QTRPVSWRLAMRSQIEDRDVL------ILRGSRVAPAIIRERERQRERERQRKRAKERHR 78
+T P S+ + RS+ R+ R R + I R+ R + K+ K+R +
Sbjct: 362 RTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 421
Query: 79 EKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRK-REKD 137
E+D I + R+R+R R+ DRD K + + E E +E + ++ +KD
Sbjct: 422 ERD-HISERRERERSTSM-RKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKD 479
Query: 138 RERQRQREI 146
R + +I
Sbjct: 480 APRTEENKI 488
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 127 bits (320), Expect = 9e-30
Identities = 67/189 (35%), Positives = 128/189 (67%), Gaps = 19/189 (10%)
Query: 54 PAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGD 113
P RE ER++ER + KR +ER +E+ RE K +++K+ ++R+R ++R+RKR
Sbjct: 28 PCTQRESERKKERREREKRKREREKERKRERGK---KEKKKRKKRERGKERERKR----- 79
Query: 114 RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173
+E E +R+E RE++R RKR+K+++++ +++ G E+ + +ER+ E E +
Sbjct: 80 --KEREKQRKERREKER-RKRKKEKKKRERKQRG-------RRERKKKKERKERERENKQ 129
Query: 174 DRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQ 233
RER+R+K+R+ +R ++R+R++E+ RER R ++K+ E+++ RER ++R KER+R+ +
Sbjct: 130 RRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNR-KERKKERERKER 188
Query: 234 REKDRDRQK 242
RE+ ++R+K
Sbjct: 189 RERKKERKK 197
Score = 127 bits (320), Expect = 9e-30
Identities = 69/183 (37%), Positives = 126/183 (68%), Gaps = 12/183 (6%)
Query: 58 RERE-RQRERERQRKRA---KERHREKDREIEKDRDRQRK-RDRERQRWRDRDRKRERWG 112
RERE R+RERE++RKR KE+ + K RE K+R+R+RK R+++R+ R+++R++ +
Sbjct: 41 REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKE 100
Query: 113 DRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERY 172
+ RE + + ER+++++RK E++RE +++RE K R+ + K+R RE+E G+
Sbjct: 101 KKKRERKQRGRRERKKKKERK-ERERENKQRRERKRKKRRKKKRRKERKREKERGK---- 155
Query: 173 RDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRER 232
RER+R+K+++ R++ RER R++ +ER+R ++ER+K+R +ER ++R K+R +R
Sbjct: 156 --RERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDR 213
Query: 233 QRE 235
Q +
Sbjct: 214 QTD 216
Score = 104 bits (260), Expect = 8e-23
Identities = 53/156 (33%), Positives = 112/156 (71%), Gaps = 8/156 (5%)
Query: 58 RERERQRERERQRK-RAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
++RER +ERER+RK R K+R +++E K + ++KR+R+++ R+R +K+ER ++R
Sbjct: 67 KKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER---KER 123
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIGI-DKDREIETEKDRDREREMGETERYRDR 175
E E +++ ER+R++ RK+++ +ER+R++E G ++ R+ +++R+++RE ER ++R
Sbjct: 124 ERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKER 183
Query: 176 ERE--RQKQRETRRDRDRERQREKEDRERDRDRQKE 209
ER+ R++++E +++R ++++R K+DR+ DR +
Sbjct: 184 ERKERRERKKERKKERRKKKER-KKDRKTDRQTDSQ 218
Score = 84.0 bits (206), Expect = 1e-16
Identities = 51/138 (36%), Positives = 92/138 (66%), Gaps = 13/138 (9%)
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
+ E+ER++ER + RKRE+++ER+R+R + EK + ++RE G+ ER R R
Sbjct: 31 QRESERKKERREREKRKREREKERKRERG---------KKEKKKRKKRERGK-ERERKR- 79
Query: 177 RERQKQRETRRDRDR-ERQREKEDRERDRDRQKEREKDRYR-ERETGRDRDKERDRERQR 234
+ER+KQR+ RR+++R +R++EK+ RER + ++ER+K + R ERE + +ER R+++R
Sbjct: 80 KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR 139
Query: 235 EKDRDRQKAIDCVPGRWE 252
+K R +++ + G+ E
Sbjct: 140 KKKRRKERKREKERGKRE 157
Score = 77.4 bits (189), Expect = 1e-14
Identities = 44/126 (34%), Positives = 82/126 (65%), Gaps = 12/126 (9%)
Query: 48 RGSRVAPAIIRERERQRE----RERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRD 103
RG R +ER+RE RER+RK+ +++ R K+R+ EK+R + R+R R++++ +
Sbjct: 109 RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGK-RERKRKKRKKEE 167
Query: 104 RDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRE 163
R++KRER ++R+ E ER+E RER+++RK+E+ ++++R+ KDR+ + + D
Sbjct: 168 REKKRER-NRKERKKERERKERRERKKERKKERRKKKERK------KDRKTDRQTDSQVF 220
Query: 164 REMGET 169
R + E+
Sbjct: 221 RPLRES 226
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 127 bits (319), Expect = 1e-29
Identities = 68/191 (35%), Positives = 126/191 (65%), Gaps = 7/191 (3%)
Query: 57 IRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDR---DRKRERWGD 113
IRERER+ E ++ K+ +E R+K+R + R R+R+++R+R+R + +RK+E
Sbjct: 38 IREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERER 97
Query: 114 RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173
+ R E E +E E+++ +K+EK +ER R + G +++R+ E +++ +ERE + ER +
Sbjct: 98 KKRRREKENKEGEEKEKRKKKEK-KERGRTSKEGKERERKEERKREERKERERKKEEREK 156
Query: 174 DRERERQKQRETRRDRDRERQR-EKEDRERDRDRQKEREKDRYRERETGRDRDKERDR-- 230
+RER+ +K+RE ++ ++E +R EKE +ER + + +E+ + RER+ R+R KER +
Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKE 216
Query: 231 ERQREKDRDRQ 241
ER++E+ +DRQ
Sbjct: 217 ERKKERQKDRQ 227
Score = 119 bits (299), Expect = 2e-27
Identities = 62/184 (33%), Positives = 128/184 (69%), Gaps = 5/184 (2%)
Query: 58 RERE-RQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
RERE R+RERE++RKR + + +K +++R+R+++R + + + KR++ ++R
Sbjct: 64 REREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKER 123
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
++ +ERER+ +RKRE+ +ER+R++E +K+RE + K R+R++ + E +++E
Sbjct: 124 GRTSKEGKERERKEERKREERKERERKKE-EREKERERKERKKRERKQVGEKEEERKEKE 182
Query: 177 RERQKQRE-TRRDRDRERQR-EKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQR 234
R+ +K+RE R++R +ER+R E+ +R+++R +++ER+K+R ++R+T R+KER + ++
Sbjct: 183 RKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNW-REKERGKRERK 241
Query: 235 EKDR 238
E+ +
Sbjct: 242 ERKK 245
Score = 116 bits (291), Expect = 2e-26
Identities = 65/191 (34%), Positives = 121/191 (63%), Gaps = 6/191 (3%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
RE ER++ER + KR +ER +E+ RE K + ++ ER+R + R K + G+ +
Sbjct: 55 RESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEK 114
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDR-EIETEKDRDR-EREMGETERYRDR 175
+ + ++ER R +E++R+ +R+RE +++R + E EK+R+R ER+ E ++ ++
Sbjct: 115 RKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEK 174
Query: 176 ERER-QKQRETRRDRDRERQREKEDRERD--RDRQKEREKDRYRERETGRDRDKE-RDRE 231
E ER +K+R+ R+ R+R R+ K++RER R+R+KER+K R++E +DR R++E
Sbjct: 175 EEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234
Query: 232 RQREKDRDRQK 242
R + + ++R+K
Sbjct: 235 RGKRERKERKK 245
Score = 106 bits (265), Expect = 2e-23
Identities = 63/198 (31%), Positives = 118/198 (59%), Gaps = 41/198 (20%)
Query: 64 RERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDR-KRERWGDRDRETETER 122
RERER+ + KE +E++ E +K+R + KR RER++ R R+R K+E+ G+R +
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER-------K 91
Query: 123 QEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQ 182
+EERER++ R+ ++++E + EK++ +++E E R +ER+++
Sbjct: 92 KEERERKKRRREKENKEGE---------------EKEKRKKKEKKERGRTSKEGKERERK 136
Query: 183 RETRRDRDRERQREKEDRERDRDR-----------------QKEREKDRYRERETGR-DR 224
E +R+ +ER+R+KE+RE++R+R +KE+E+ ++RE R +R
Sbjct: 137 EERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER 196
Query: 225 DKERDRERQREKDRDRQK 242
KER+R+ +RE+ ++R+K
Sbjct: 197 KKERERKERRERKKERKK 214
Score = 60.1 bits (144), Expect = 2e-09
Identities = 25/76 (32%), Positives = 55/76 (72%), Gaps = 1/76 (1%)
Query: 167 GETERYRDRERERQKQRETRRDRDRERQREKEDRE-RDRDRQKEREKDRYRERETGRDRD 225
G R+RERE + ++E +++R+ ER++E+ +RE R R+R+KER+++R ++ + G +
Sbjct: 33 GWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92
Query: 226 KERDRERQREKDRDRQ 241
+ER+R+++R + +++
Sbjct: 93 EERERKKRRREKENKE 108
Score = 52.4 bits (124), Expect = 5e-07
Identities = 29/86 (33%), Positives = 55/86 (63%), Gaps = 6/86 (6%)
Query: 48 RGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRK 107
R R + + E ++E+ER+ ++ +ER+R K+R+ E++R +R+R +ER+ + +RK
Sbjct: 163 RKKRERKQVGEKEEERKEKERKERKKRERNR-KERKKERERKERRERKKERK--KKEERK 219
Query: 108 RERWGDRD---RETETERQEERERQR 130
+ER DR RE E ++E +ER++
Sbjct: 220 KERQKDRQTNWREKERGKRERKERKK 245
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 122 bits (307), Expect = 3e-28
Identities = 74/215 (34%), Positives = 116/215 (53%), Gaps = 33/215 (15%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDR-DR 116
RE ER++ER+R + AKER +E+ R DR +R+R R R+R R R R R+R GDR DR
Sbjct: 293 RELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDR 352
Query: 117 ETETERQEERERQRDR--------KREKDRERQRQREIGIDKDREIETEKDRDREREMGE 168
+ E E++ ER R+RDR +REK+RER R+R K++ E + + +E +
Sbjct: 353 DREREKENERGRRRDRDYDKERGNEREKERERSRER----SKEQRSRGEVEEKKHKEDKD 408
Query: 169 TERYRDRERERQKQRETRRDRDRERQ----------------REKEDRERDRDRQKEREK 212
R+RD +R+ +K+++ R R RER+ R KE + ++ KE+
Sbjct: 409 DRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSN 468
Query: 213 DRYRERETGR----DRDKERDRERQREKDRDRQKA 243
R R GR ++ K+R+ +EK R R ++
Sbjct: 469 KRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRS 503
Score = 110 bits (274), Expect = 2e-24
Identities = 62/220 (28%), Positives = 113/220 (51%), Gaps = 9/220 (4%)
Query: 32 RLAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKER---HREKDREIEKDR 88
R + + ++R+ R + + R R R RER R R R+++R R++DRE EK+
Sbjct: 301 RQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKEN 360
Query: 89 DRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGI 148
+R R+RDR+ + R +R++ER R+R E Q R ++K ++D++ +R R+
Sbjct: 361 ERGRRRDRDYDKERGNEREKERERSRERSKE---QRSRGEVEEKKHKEDKDDRRHRDDKR 417
Query: 149 DKDREIETEKDRDREREMGETERYRD---RERERQKQRETRRDRDRERQREKEDRERDRD 205
D +E + + R RER+ R R+ R R R K++ ++ + + + K R +
Sbjct: 418 DSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQG 477
Query: 206 RQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAID 245
R EK + RE +++ ++R R ++R RD + D
Sbjct: 478 RTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKD 517
Score = 108 bits (269), Expect = 7e-24
Identities = 73/211 (34%), Positives = 112/211 (53%), Gaps = 23/211 (10%)
Query: 54 PAIIRERERQRERERQRK---RAKERHREKDREIEKDRDRQRKRD----RERQRWRDRDR 106
P +++ Q+ + R RK KE E DR +E+ R R +R R +R R R
Sbjct: 222 PVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSH 281
Query: 107 KRERWGDRDRETETERQEERERQRDRKREKDRERQRQREI--GIDK--DREIETEKDRDR 162
RE G + E ER++ER+R +E+++ER+R R I G+++ R E + R R
Sbjct: 282 HREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSR 341
Query: 163 EREMGETERYRDRERERQKQRETRRDRD----RERQREKEDRERDRDRQKER-------E 211
R+ R RDRERE++ +R RRDRD R +REKE RER R+R KE+ E
Sbjct: 342 SRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKE-RERSRERSKEQRSRGEVEE 400
Query: 212 KDRYRERETGRDRDKERDRERQREKDRDRQK 242
K +++ R RD +RD +++++ R R +
Sbjct: 401 KKHKEDKDDRRHRDDKRDSKKEKKHSRSRSR 431
Score = 107 bits (267), Expect = 1e-23
Identities = 77/240 (32%), Positives = 120/240 (50%), Gaps = 30/240 (12%)
Query: 14 TITESFSQLLLQTRPVSWRLAMRSQIEDRDVLILR-GSRVAPAIIRERERQRERERQRK- 71
T E FS L + PV + + QI+ R I + G A I R ER+R R +R
Sbjct: 209 TKLEWFSTLFPRI-PVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSL 267
Query: 72 ---------RAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETER 122
R++ HRE DR+ +R+++R+R ++R++ER R + ER
Sbjct: 268 SPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLER 327
Query: 123 QEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQ 182
+ R R+R R R + R+R+ R +DRDRERE E ER R R+R+ K+
Sbjct: 328 RRSRSRERHRSRSRSRDRKGDR-------------RDRDREREK-ENERGRRRDRDYDKE 373
Query: 183 RETRRDRDRERQREKEDRERDR----DRQKEREKDRYRERETGRDRDKERDRERQREKDR 238
R R+++RER RE+ +R R +++ + +KD R R+ RD KE+ R R ++R
Sbjct: 374 RGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRER 433
Score = 94.4 bits (233), Expect = 1e-19
Identities = 50/186 (26%), Positives = 92/186 (49%), Gaps = 12/186 (6%)
Query: 60 RERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETE 119
R+R RERE++ +R + R R+ D+E +R+++R+R RER + R R ++ + +
Sbjct: 350 RDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSK---EQRSRGEVEEKKHKED 406
Query: 120 TERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERER 179
+ + R+ +RD K+EK R R RE + R R R G+ R R +E+
Sbjct: 407 KDDRRHRDDKRDSKKEKKHSRSRSRE---------RKHRSRSRSRNAGKRSRSRSKEKSS 457
Query: 180 QKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRD 239
+ + E++ ++ + + R ++ K+RE +E+ R R KER +R +D
Sbjct: 458 KHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKD 517
Query: 240 RQKAID 245
+ D
Sbjct: 518 QSDKHD 523
Score = 89.7 bits (221), Expect = 3e-18
Identities = 53/187 (28%), Positives = 92/187 (49%), Gaps = 6/187 (3%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQR-KRDRERQRWRDRDRKRERWGDRDR 116
RERE++ ER R+R R ++ R +RE E++R R+R K R R ++ K ++ R R
Sbjct: 354 REREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHR 413
Query: 117 ETETERQEERERQRDRKRE-KDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDR 175
+ + + ++E++ R R RE K R R R R G + R EK + E E R R
Sbjct: 414 DDKRDSKKEKKHSRSRSRERKHRSRSRSRNAG-KRSRSRSKEKSSKHKNESKEKSNKRSR 472
Query: 176 ERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQRE 235
+ + + + RE K E+ R R + +E+ R+ +D+ + DR R +
Sbjct: 473 SGSQGRTDSVEKSKKREHSPSK---EKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQS 529
Query: 236 KDRDRQK 242
+++ Q+
Sbjct: 530 IEQESQE 536
Score = 79.7 bits (195), Expect = 3e-15
Identities = 47/173 (27%), Positives = 91/173 (52%), Gaps = 14/173 (8%)
Query: 58 RERERQRERERQRKRAKE---RHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDR 114
R ER++ERER R+R+KE R ++++ ++D+D +R RD +R +++ R R +R
Sbjct: 374 RGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRER 433
Query: 115 DRETETERQEERERQRDRKREK-------DRERQRQREIGIDKDREIETEKDRDREREMG 167
+ + + +R R R +EK +E+ +R + R EK + RE
Sbjct: 434 KHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREH--- 490
Query: 168 ETERYRDRERERQKQRETRRDR-DRERQREKEDRERDRDRQKEREKDRYRERE 219
+ + R+R R K+R +RD D + Q +K DR R + ++E ++ +++ ++
Sbjct: 491 SPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543
Score = 72.4 bits (176), Expect = 4e-13
Identities = 54/158 (34%), Positives = 76/158 (48%), Gaps = 28/158 (17%)
Query: 99 QRWRDRDRKRERWGDRDRETETERQEERER----------QRDRKREKDRERQRQREIGI 148
Q+ + R RK ++ G E E +R ER R +R +R + R R+
Sbjct: 231 QQIKTRPRKIKKDGKEGAE-EIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSS 289
Query: 149 DKDREIETEKDRDR-EREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQ 207
DRE+E EK+R R ERE E E+ R R R + E RR R RER R R R RDR+
Sbjct: 290 SFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRS---RSRSRDRK 346
Query: 208 KEREKDRYRERETGRDRDKERDRERQREKDRDRQKAID 245
+R RD++R+RE++ E+ R R + D
Sbjct: 347 GDR-------------RDRDREREKENERGRRRDRDYD 371
Score = 52.0 bits (123), Expect = 6e-07
Identities = 35/123 (28%), Positives = 61/123 (49%), Gaps = 15/123 (12%)
Query: 124 EERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMG---ETERYRDRERERQ 180
+++ + R RK +KD + + + DR +E + R R + R R R R+
Sbjct: 230 DQQIKTRPRKIKKDGKEGAE-----EIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHRE 284
Query: 181 KQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDR 240
+ DR+ ER++E++ ER+ KEREK+R R R D+ +R R R ++R R
Sbjct: 285 GHGSSSFDRELEREKERQRLEREA---KEREKERRRSRSI----DRGLERRRSRSRERHR 337
Query: 241 QKA 243
++
Sbjct: 338 SRS 340
Score = 43.1 bits (100), Expect = 3e-04
Identities = 27/113 (23%), Positives = 54/113 (47%), Gaps = 16/113 (14%)
Query: 58 RERERQRER---ERQRKRAKER---HREKDREIEKDRDR----------QRKRDRERQRW 101
+ R R R R +R R R+KE+ H+ + +E R R ++ + RE
Sbjct: 434 KHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPS 493
Query: 102 RDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREI 154
+++ RKR R +R + + +++ + DR+R + E++ Q + +KD +
Sbjct: 494 KEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDETV 546
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 108 bits (271), Expect = 4e-24
Identities = 71/205 (34%), Positives = 118/205 (57%), Gaps = 28/205 (13%)
Query: 54 PAIIRERERQRERERQRKRA-KERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWG 112
P ++ + R +R+++RA +E+ E++RE+E+ R+R R + W DRD+ RE
Sbjct: 1122 PPPVQPPQHPRAEQREQERAVREQWAEREREMER-----RERTRSEREW-DRDKVREGPR 1175
Query: 113 DRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIET---------------- 156
R R + R++ER + +++K EK + Q + + D +T
Sbjct: 1176 SRSRSRD-RRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQI 1234
Query: 157 -EKDRDR-EREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDR 214
+K+ +R ER +R +++E E QK+RE +R+R RQ E+E R R+ R+++RE++R
Sbjct: 1235 VQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKR-REHSRERDRERER 1293
Query: 215 YRERETG-RDRDKERDRERQREKDR 238
RER+ G RDRD+ERDRER RE+DR
Sbjct: 1294 ERERDRGDRDRDRERDRERGRERDR 1318
Score = 104 bits (259), Expect = 1e-22
Identities = 70/201 (34%), Positives = 109/201 (54%), Gaps = 20/201 (9%)
Query: 58 RERERQ-RERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
RE+ER RE+ +R+R ER E E DRD+ R+ R R R RDR RK + +
Sbjct: 1136 REQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERA---KSK 1192
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIGI-----------DKDREIETEKDRDRERE 165
E ++E++E+ + + K D R+ + I K+ E E+ ++RE+
Sbjct: 1193 EKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAE-RAERAKEREKR 1251
Query: 166 MGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRY---RERETGR 222
E E +ERE++ +RE R +RE++RE RERDR+R++ERE+DR R+RE R
Sbjct: 1252 RKEQEEEEQKEREKEAERERNRQLEREKRRE-HSRERDRERERERERDRGDRDRDRERDR 1310
Query: 223 DRDKERDRERQREKDRDRQKA 243
+R +ERDR + R R ++
Sbjct: 1311 ERGRERDRRDTKRHSRSRSRS 1331
Score = 88.2 bits (217), Expect = 7e-18
Identities = 68/211 (32%), Positives = 110/211 (52%), Gaps = 50/211 (23%)
Query: 57 IRER--ERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRER-QRWRDRDRKRER--- 110
+RE+ ER+RE ER+ + ER ++D+ E R R R RDR R +R + +++K E+
Sbjct: 1142 VREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEK 1201
Query: 111 ---------WGDRDRETET----------------------ERQEERERQRDRKREKDRE 139
D R+T+ ER +ERE++R +++E++ +
Sbjct: 1202 AQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRR-KEQEEEEQ 1260
Query: 140 RQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQK-QRETRRDRDRERQREKE 198
++R++E +++R++E EK R+ RE +R R+RERER + R+ R+RDRER RE
Sbjct: 1261 KEREKEAERERNRQLEREKRREHSRER---DRERERERERDRGDRDRDRERDRERGRE-- 1315
Query: 199 DRERDRDRQKEREKDRYRERETG-RDRDKER 228
RDR+ + R R R T RDR R
Sbjct: 1316 -----RDRRDTKRHSRSRSRSTPVRDRGGRR 1341
Score = 56.2 bits (134), Expect = 3e-08
Identities = 57/196 (29%), Positives = 90/196 (45%), Gaps = 28/196 (14%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
R+ ER+ R RQ + AK + E E+D++ + R R DR+ K E
Sbjct: 222 RKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVR---ADRNLKTE-------- 270
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEK-DRDRERE-MGETERYRDR 175
E E +EE E + D + E D E Q+ RE I K+ + E E+ R + E M E + R +
Sbjct: 271 -EEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQ 329
Query: 176 ERE--------RQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKE 227
E+E + Q E R+ +Q+EKE + ++ERE + + +++ K
Sbjct: 330 EQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEERE---IKSSQGLKEKSKS 386
Query: 228 RDRERQREKDRDRQKA 243
R E DR+KA
Sbjct: 387 PSPPRLTE---DRKKA 399
Score = 54.7 bits (130), Expect = 9e-08
Identities = 42/163 (25%), Positives = 75/163 (46%), Gaps = 4/163 (2%)
Query: 83 EIEKDRDRQRKRDRERQRWRDRDRKRERWGDR--DRETETERQEERERQRDRKREKDRER 140
E+E R RK + D D ++ R G+R R + + E + + E+D+E
Sbjct: 195 ELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQET 254
Query: 141 QRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDR 200
R + + DR ++TE++ + E E E + + + E QK RE ++ + + E+ R
Sbjct: 255 P-SRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPR 313
Query: 201 ERDRDRQKEREKDRYRERET-GRDRDKERDRERQREKDRDRQK 242
+ + ER K R +E+E R R +E R+ RQ+
Sbjct: 314 VKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQ 356
Score = 29.3 bits (64), Expect = 4.1
Identities = 22/116 (18%), Positives = 38/116 (32%), Gaps = 6/116 (5%)
Query: 46 ILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRD 105
+L R+ + R R++ R + R ++RD + R
Sbjct: 564 LLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANP 623
Query: 106 RKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRD 161
R R + G R E R R R R R ++ G+ +D + +D
Sbjct: 624 RGRPKMGSR------STSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKD 673
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 103 bits (258), Expect = 1e-22
Identities = 61/197 (30%), Positives = 99/197 (50%), Gaps = 11/197 (5%)
Query: 57 IRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDR-D 115
+ R + R R R++ER R+ D E K R R R ++ R +D+ K+ + + D
Sbjct: 31 VSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHND 90
Query: 116 RETETERQEER----ERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETER 171
+E +++ ER E DR + K+R+ R R + RE + R RER+ +
Sbjct: 91 KEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRE-RRHRSRSRERK-----K 144
Query: 172 YRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRE 231
R R RER+K R R+R + R R +E + R R R + R + R+R R R R + RDR+
Sbjct: 145 SRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRK 204
Query: 232 RQREKDRDRQKAIDCVP 248
++ EK R +++ P
Sbjct: 205 KRIEKPRRFSRSLSRTP 221
Score = 103 bits (257), Expect = 2e-22
Identities = 62/193 (32%), Positives = 102/193 (52%), Gaps = 9/193 (4%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRE--RWGDRD 115
R++++++ RA + H + R + R+R+RK D E ++ R R R +E R +D
Sbjct: 20 RDKKKEQSEVSVSPRASKHHYSRSRS--RSRERKRKSDNEGRKHRSRSRSKEGRRHESKD 77
Query: 116 RETETERQEERERQRDRKREKDRERQRQREIGID--KDREIETEKDRDREREMGETERYR 173
+ ++ + EE ++ +K RER E G D K +E ++ + R R R+R
Sbjct: 78 KSSKKHKSEE-HNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHR 136
Query: 174 DRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKD-RYRERETGRDRDKERDRER 232
R RER+K R R+R + R R +E R++ R R +ER++ R R R R R + R R R
Sbjct: 137 SRSRERKKSRSRSRERKKSRSRSRE-RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSR 195
Query: 233 QREKDRDRQKAID 245
R + RDR+K I+
Sbjct: 196 TRSRSRDRKKRIE 208
Score = 88.6 bits (218), Expect = 6e-18
Identities = 58/210 (27%), Positives = 91/210 (43%), Gaps = 7/210 (3%)
Query: 58 RERERQRERERQRKRAK-ERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
+E R +++ K+ K E H +K+ +K R+R + R + ++RK R R
Sbjct: 68 KEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 127
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
ER R R R R+R+K R R R+R+ + RE + + R RER+ R R R
Sbjct: 128 SRSRER---RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS 184
Query: 177 RERQKQRETRRDRDRERQREK---EDRERDRDRQKEREKDRYRERETGRDRDKERDRERQ 233
R R + R R R R R R+K + R R + +R R T D + R +
Sbjct: 185 RHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLE 244
Query: 234 REKDRDRQKAIDCVPGRWEVTVMAVDCVPG 263
R K Q+ + V + + + A G
Sbjct: 245 RAKKLQEQREKEMVEKQKQQEIAAAAATGG 274
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 101 bits (252), Expect = 7e-22
Identities = 54/194 (27%), Positives = 120/194 (61%), Gaps = 11/194 (5%)
Query: 59 ERERQRERERQRKRAKE----RHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDR 114
E+++QR R Q+ R K+ R ++++R +++R Q++ RE+Q R+++ +RE+ R
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353
Query: 115 DRETETERQEERERQRDRKREKD--RERQRQREIGIDKDREIETEKDRDREREMGETERY 172
++E E Q+ R Q + +RE+ RE+Q +RE + +++++ E+ RE+++ ++
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 413
Query: 173 RDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDR----YRERETGRDRDKER 228
R RE++ +++++ RR+++ ER +K ++ER R K +++R RE ET R + R
Sbjct: 414 R-REQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR 472
Query: 229 DRERQREKDRDRQK 242
++ +R+++ +R++
Sbjct: 473 KQQLKRDQEEERRE 486
Score = 100 bits (249), Expect = 1e-21
Identities = 61/227 (26%), Positives = 126/227 (55%), Gaps = 43/227 (18%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRD---RERQRWRDRDRKR------- 108
+R RQ+ +E++R+ A+ + + +E + RDRQR+ + R+RQ W++R+ +R
Sbjct: 135 QRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQ 194
Query: 109 -------ERWGDRDRETETERQEERERQRDRKREKDRERQ------------RQREIGID 149
E + D ++ E E R + R+ K+++ RERQ R+RE +
Sbjct: 195 SCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLR 254
Query: 150 KDREIETEKDRDREREMGETERY----------RDRERERQKQRETRRDRDRERQREKED 199
K+ E E++ R+RE+ E E R+R+ E Q+Q+ RR++ R++E+E
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
Query: 200 RERDRDRQKEREK----DRYRERETGRDRDKERDRERQREKDRDRQK 242
RE+ +R++++E+ + RE++ R++++ R+++ +RE++ +R++
Sbjct: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERRE 361
Score = 98.6 bits (244), Expect = 6e-21
Identities = 55/197 (27%), Positives = 114/197 (57%), Gaps = 12/197 (6%)
Query: 58 RERERQRERERQRKRAKERHREKD--REIEKDRDRQRKRDRERQRWRDRDRKRERWGDRD 115
R +++ RE+Q +R +E RE+ RE E++R Q+ R + + R++ +RE+ R+
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 116 RETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDR 175
++ E+Q RE+Q R+++ RE+Q +RE + +++++ E++ +R + E ER R
Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR 446
Query: 176 ERERQKQRETRRDRDRERQREKEDRERD---RDRQKER-------EKDRYRERETGRDRD 225
+ Q++R R+ E +R +++R + RD+++ER E++ RE++ R++
Sbjct: 447 LKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
Query: 226 KERDRERQREKDRDRQK 242
R++E +RE+ RQ+
Sbjct: 507 LRREQEERREQRLKRQE 523
Score = 97.4 bits (241), Expect = 1e-20
Identities = 52/185 (28%), Positives = 111/185 (60%), Gaps = 4/185 (2%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
+E E+ +E E QR+R + E+ R++E+ R+ +++ E+Q+ R R RE+ R +E
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLR---REQQLRRKQE 311
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRER 177
E Q+E R++ +RE+ ER R++++ +++ E + R++E E E + R++E
Sbjct: 312 EERREQQEERREQQERREQQEER-REQQLRREQEERREQQLRREQEEERREQQLRREQEE 370
Query: 178 ERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKD 237
ER++Q+ R + R Q+ + +++ R++Q RE+ RE++ R++ R+++ +RE++
Sbjct: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQE 430
Query: 238 RDRQK 242
+R +
Sbjct: 431 EERHE 435
Score = 96.7 bits (239), Expect = 2e-20
Identities = 64/210 (30%), Positives = 117/210 (55%), Gaps = 5/210 (2%)
Query: 36 RSQIEDRDVLILRGS---RVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQR 92
R Q E+R LR R + RE+E +R ++ R+ +E RE+ E+ R++
Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ 387
Query: 93 KRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDR 152
+ RE+Q R++ +RE+ R+++ E+Q RE+Q R++E++R Q+ + ++
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447
Query: 153 EIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREK 212
+ E E+ RD + ETER+ R++Q +R+ +R RER + E+ ER R++Q+ RE+
Sbjct: 448 KREQEERRDWLKREEETERHEQERRKQQLKRDQEEER-RERWLKLEEEER-REQQERREQ 505
Query: 213 DRYRERETGRDRDKERDRERQREKDRDRQK 242
RE+E R++ +R E +R + R R +
Sbjct: 506 QLRREQEERREQRLKRQEEEERLQQRLRSE 535
Score = 96.3 bits (238), Expect = 3e-20
Identities = 57/189 (30%), Positives = 113/189 (59%), Gaps = 8/189 (4%)
Query: 60 RERQRERERQRKRAKERHREKD--REIEKDRDRQR-KRDRERQRWRDRDRKRERWGDRDR 116
RE+Q RE+Q +R ++ RE+ RE E++R Q+ +++R QR + +R W R+
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE 462
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
ETE QE R++Q R +E++R R+R ++ ++ RE + +++ RE E R +
Sbjct: 463 ETERHEQERRKQQLKRDQEEER-RERWLKLEEEERREQQERREQQLRREQEERREQRLKR 521
Query: 177 RERQKQRETRRDRDRERQREKEDRERD---RDRQKEREKDRYRERETGRDRDKERDRERQ 233
+E +++ + R +++ +RE+E+R R+ +K E++R RE+ R++++ RD+ +
Sbjct: 522 QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER-REQRLKREQEERRDQLLK 580
Query: 234 REKDRDRQK 242
RE++R +Q+
Sbjct: 581 REEERRQQR 589
Score = 95.9 bits (237), Expect = 4e-20
Identities = 54/185 (29%), Positives = 114/185 (61%), Gaps = 5/185 (2%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
R+RE Q E E+ RK ++ R + +E E+ + R R R+++ +R ++ +R+ ++ R+++
Sbjct: 267 RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLR-REQQLRRKQEEERREQQEERREQQ 325
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRER 177
E+QEER Q+ R+ +++R Q+ R ++ RE + ++++ ER + R + R
Sbjct: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385
Query: 178 ERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKD 237
E+Q +RE + R+++ +RE++ R R++Q RE+ RE++ R++++ER E++ E++
Sbjct: 386 EQQLRREQQLRREQQLRREQQLR---REQQLRREQQLRREQQLRREQEEER-HEQKHEQE 441
Query: 238 RDRQK 242
R Q+
Sbjct: 442 RREQR 446
Score = 94.4 bits (233), Expect = 1e-19
Identities = 62/200 (31%), Positives = 123/200 (61%), Gaps = 17/200 (8%)
Query: 60 RERQRERERQRKRAKERHRE--KDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
R+RQ +ER+ +RA+E + K E E+ D ++ R RE R + R+ ++ R+R+
Sbjct: 175 RQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQ 234
Query: 118 T----ETERQEERERQRDRKREKDR----ERQRQREIGIDKD--REIE-TEKDRDREREM 166
E E +E R+R+ ++E+++ E QRQRE+ +++ R++E E R+R+ E
Sbjct: 235 DRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEE 294
Query: 167 GETERYRDRERERQKQRETRRDRDRERQREKEDRERD---RDRQKEREKDRYRERETGRD 223
+ +R R ++ R+KQ E RR++ ER+ ++E RE+ R++Q RE++ RE++ R+
Sbjct: 295 QQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRRE 354
Query: 224 RDKE-RDRERQREKDRDRQK 242
+++E R+++ +RE++ +R++
Sbjct: 355 QEEERREQQLRREQEEERRE 374
Score = 94.0 bits (232), Expect = 1e-19
Identities = 49/190 (25%), Positives = 116/190 (61%), Gaps = 8/190 (4%)
Query: 57 IRERERQRERERQRKRAKERHRE-----KDREIEKDRDRQRKRDRERQRWRDRDRKRERW 111
++E E QR+RE Q + + R E ++R+ E+ + ++ +R+++ +R ++ +R+ ++
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Query: 112 GDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETER 171
R+++ E+QEER Q+ R+ +++R Q+ R ++ RE + ++++ ER + R
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR 379
Query: 172 YRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRE 231
+ RE+Q +RE + R+++ +RE++ R R++Q RE+ RE++ R++++ER +
Sbjct: 380 EQQLRREQQLRREQQLRREQQLRREQQLR---REQQLRREQQLRREQQLRREQEEERHEQ 436
Query: 232 RQREKDRDRQ 241
+ ++ R+++
Sbjct: 437 KHEQERREQR 446
Score = 94.0 bits (232), Expect = 1e-19
Identities = 53/192 (27%), Positives = 119/192 (61%), Gaps = 10/192 (5%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
E R+++ ER+ ++ + +E+ RE + R+++ +R+++ +R ++ +R+ ++ E
Sbjct: 312 EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Query: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREM-GETERYRDRER 177
E+Q RE+Q R+++ RE+Q +RE + +++++ E+ RE+++ E + R++E
Sbjct: 372 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431
Query: 178 ERQKQRETRRDRDRERQREKEDRERD---RDRQKEREKDRYRERETGRDRDKERDRER-- 232
ER +Q+ + R++ +RE+E+R RD R+ + ER + R+++ RD+++ER RER
Sbjct: 432 ERHEQKHEQERREQRLKREQEER-RDWLKREEETERHEQERRKQQLKRDQEEER-RERWL 489
Query: 233 --QREKDRDRQK 242
+ E+ R++Q+
Sbjct: 490 KLEEEERREQQE 501
Score = 93.6 bits (231), Expect = 2e-19
Identities = 66/229 (28%), Positives = 120/229 (52%), Gaps = 18/229 (7%)
Query: 32 RLAMRSQIEDRDVLILRGSRVAPAIIRERERQRE----RERQRKRAKERHREK-DREIEK 86
R R + ++ + + + R + RE+E +RE RE +++ +ER ++ RE E+
Sbjct: 514 RREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE 573
Query: 87 DRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDR-KREKDRERQRQRE 145
RD+ KR+ ER++ R + + ER R + E ER E+ ER+ R KRE+ E +RQ+
Sbjct: 574 RRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL 633
Query: 146 IGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQRE--KEDRERD 203
+ ++ E ++ R ++E E R+ E ER +QR R + R++E +E++E+
Sbjct: 634 LKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQA 693
Query: 204 RDR----------QKEREKDRYRERETGRDRDKERDRERQREKDRDRQK 242
R+R Q E E D + + R R +E R RQ ++++ R++
Sbjct: 694 RERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742
Score = 93.6 bits (231), Expect = 2e-19
Identities = 52/203 (25%), Positives = 114/203 (56%), Gaps = 19/203 (9%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
RE+ R++E ERQ ++ E +E+++ + ++R+++R ++RERQ + + ++E E
Sbjct: 1008 REKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEE 1067
Query: 118 TETERQEERERQ------------------RDRKREKDRERQRQREIGIDKDREIETEKD 159
ET R++E ERQ +++R ++RERQ + E + ++ E ++
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127
Query: 160 RDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERE 219
R++ R +YR+ E +Q++ + R+ +R+R++ +R+ + + ++E+++ RE
Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL-RE 1186
Query: 220 TGRDRDKERDRERQREKDRDRQK 242
R +ER+R+ + E++ RQK
Sbjct: 1187 EQEKRRQERERQYREEEELQRQK 1209
Score = 93.2 bits (230), Expect = 2e-19
Identities = 60/221 (27%), Positives = 124/221 (56%), Gaps = 24/221 (10%)
Query: 38 QIEDRDVLILRGSRVAPAIIRERERQRERERQ------------RKRAKERHREKDREIE 85
Q+ R++L LR RE ++Q+ RERQ RKR +E+++ E
Sbjct: 209 QLRRRELLELRRKG------REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQE 262
Query: 86 KDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQRE 145
++ RQR+ E ++ R +R+ R R+R+ E ++Q+ R++ +R+++ ER+ Q+E
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQELR---RERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Query: 146 IGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERD-- 203
++ E +++R RE+++ + R ++ R++Q E RR++ R++E+E RE+
Sbjct: 320 ERREQQERREQQEER-REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLR 378
Query: 204 RDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAI 244
R++Q RE+ RE++ R++ R+++ +RE+ R++ +
Sbjct: 379 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419
Score = 93.2 bits (230), Expect = 2e-19
Identities = 58/230 (25%), Positives = 123/230 (53%), Gaps = 26/230 (11%)
Query: 34 AMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRK 93
A++ Q+ L+ RE+ R++E+ERQ + ++ +E+++ + ++R+++R+
Sbjct: 894 ALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR 953
Query: 94 RDRERQRWRDRD---------------RKRERWGDRDRETETERQEERE---RQRDRKRE 135
++RERQ +D+ R+R+ + RE E +QEE + +R+++R
Sbjct: 954 QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR 1013
Query: 136 KDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQ-------KQRETRRD 188
++ ERQ +++ + ++ E ++R++ R +YR+ E +Q ++RETRR
Sbjct: 1014 QEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRR 1073
Query: 189 RDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDR 238
++ ERQ KE+ + + Q RE+ R R+ R+R + E Q+E+++
Sbjct: 1074 QELERQYRKEEELQQEEEQLLREEPEKRRRQE-RERQCREEEELQQEEEQ 1122
Score = 92.0 bits (227), Expect = 5e-19
Identities = 51/185 (27%), Positives = 106/185 (57%), Gaps = 4/185 (2%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
RE++ +RE++ +R++ +ERH +K E E+ R ++ ER+ W R+ + ER R+
Sbjct: 415 REQQLRREQQLRREQEEERHEQK-HEQERREQRLKREQEERRDWLKREEETERHEQERRK 473
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRER 177
+ +R +E ER+ + ++ ER+ Q+E + R + E+ R + E ER + R R
Sbjct: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
Query: 178 ERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKD 237
Q+ R + +R + + +E++ +++R+++R K RE+E RD+ +R+ ER++++
Sbjct: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLK---REQEERRDQLLKREEERRQQRL 590
Query: 238 RDRQK 242
+ Q+
Sbjct: 591 KREQE 595
Score = 92.0 bits (227), Expect = 5e-19
Identities = 54/193 (27%), Positives = 106/193 (54%), Gaps = 10/193 (5%)
Query: 60 RERQRERERQRKRAKERHREKDREIEKDRDRQRKRD---RERQRWRDRDRKRERWGDRDR 116
RE+Q RE++ +R +++H ++ RE R+++ +RD RE + R +R++ RD+
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 117 ETET-------ERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGET 169
E E E +E RE+Q R+++ RE++ +RE + + E E + R R +
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR 540
Query: 170 ERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERD 229
E+ RE+ +++ E R +++R QR K ++E RD+ +RE++R ++R ++
Sbjct: 541 EQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ 600
Query: 230 RERQREKDRDRQK 242
R ++ E +R Q+
Sbjct: 601 RLKREEVERLEQE 613
Score = 90.9 bits (224), Expect = 1e-18
Identities = 58/232 (25%), Positives = 125/232 (53%), Gaps = 22/232 (9%)
Query: 31 WRLAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDR 90
WR R + ++R+ ++ E E + E+ R+R R K RE EK + R
Sbjct: 174 WR--QRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE-EKQQQR 230
Query: 91 QRKRDR-----ERQRWRDRD----RKRERWGDRDRETETERQEERER---------QRDR 132
+ ++DR E + WR R+ ++ E+ + + + + E QEE E+ +R+R
Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRER 290
Query: 133 KREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRE 192
+ E+ ++++ +RE + + +E E + ++ RE E ++ RE+Q +RE R+++
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQ 350
Query: 193 RQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAI 244
+RE+E+ R++ ++E+E++R RE++ R++ R+++ +RE+ R++ +
Sbjct: 351 LRREQEEERREQQLRREQEEER-REQQLRREQQLRREQQLRREQQLRREQQL 401
Score = 90.9 bits (224), Expect = 1e-18
Identities = 56/186 (30%), Positives = 109/186 (58%), Gaps = 7/186 (3%)
Query: 60 RERQRERERQRKRAKERHREKD--REIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
RE+Q RE+Q +R ++ RE+ RE + R++Q +R+++ +R ++ +R ++ RE
Sbjct: 385 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE 444
Query: 118 TETER-QEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
+R QEER R+ E +R Q +R+ + +D+E E+ R+R ++ E ER +E
Sbjct: 445 QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE---EERRERWLKLEEEERREQQE 501
Query: 177 RERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREK 236
R Q+ R + +R +R + +E+ ER + R + ++ R RE+E R++ +R+ E++ E+
Sbjct: 502 RREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR-REQEERREQLLKREEEKRLEQ 560
Query: 237 DRDRQK 242
+R Q+
Sbjct: 561 ERREQR 566
Score = 90.5 bits (223), Expect = 2e-18
Identities = 51/185 (27%), Positives = 106/185 (57%), Gaps = 3/185 (1%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
RE+ R +ERERQ + +E +E+++ + ++R+ +R+++ ERQ ++ + ++E E
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKD-RDREREMGETERYRDRE 176
E R++ERERQ + E +E ++ +K R E E+ R+ E E E+ E
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREE 1157
Query: 177 RERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREK 236
E+++++E R E + ++E+ + R+ Q++R ++ RER+ + + +R + +QR +
Sbjct: 1158 PEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE--RERQYREEEELQRQKRKQRYR 1215
Query: 237 DRDRQ 241
D D++
Sbjct: 1216 DEDQR 1220
Score = 89.7 bits (221), Expect = 3e-18
Identities = 55/201 (27%), Positives = 115/201 (57%), Gaps = 19/201 (9%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
++ER RE+ER+R + ++RH ++ ++E++ ++ KR R+R+ ++ RE ++ R
Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKR-RDRKSQEEKQLLREEREEKRRRQ 1332
Query: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERE 178
ET+R+ E Q ++RE+ R+++R+ K RE E + + E +R R +ERE
Sbjct: 1333 ETDRKFREEEQLLQEREEQPLRRQERD---RKFREEELRHQEQGRKFLEEEQRLRRQERE 1389
Query: 179 R------------QKQRETRRDRDRERQREKED---RERDRDRQKEREKDRYRERETGRD 223
R +++++ R+DRDR+ + E++ +ERDR ++E ++ R +ERE
Sbjct: 1390 RKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFL 1449
Query: 224 RDKERDRERQREKDRDRQKAI 244
++++ R+ + K R+ ++ +
Sbjct: 1450 EEEQQLRQERHRKFREEEQLL 1470
Score = 89.4 bits (220), Expect = 3e-18
Identities = 55/190 (28%), Positives = 116/190 (61%), Gaps = 10/190 (5%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
RE+ R++E ERQ + +E +E+++ + ++ +++R+++ ERQ +R+ + ++ RE
Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQ-YREEEELQQEEEQLLRE 1186
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERY-RDRE 176
+ +R++ERERQ + E R++++QR D+ +++ + + ++E + + + Y + RE
Sbjct: 1187 EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246
Query: 177 RERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDR----DKERDRER 232
E+ +Q E + RDR+ Q +D + Q+ER++++ R R RDR +++ +RE
Sbjct: 1247 NEQFRQLEDSQLRDRQSQ---QDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREE 1303
Query: 233 QRE-KDRDRQ 241
Q+E K RDR+
Sbjct: 1304 QKEAKRRDRK 1313
Score = 89.4 bits (220), Expect = 3e-18
Identities = 75/252 (29%), Positives = 124/252 (49%), Gaps = 59/252 (23%)
Query: 38 QIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDR--------EIEKD-- 87
+++ + +LR + RER+ + E E QR++ K+R+R++D+ E EK+
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
Query: 88 ------------------------RDRQRKRDRER----QRWRDRDRKRERWGDRDR--- 116
RDRQ ++D + Q+ RDR+++R RW RDR
Sbjct: 1235 VRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFP 1294
Query: 117 -ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDR 175
E + ER+E++E +R R R+ E+Q RE +K R ET++ E ++ +
Sbjct: 1295 EEEQLEREEQKEAKR-RDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQ------- 1346
Query: 176 ERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKE------RD 229
ERE Q R RDR + RE+E R +++ R+ E+ R R +E R KE ++
Sbjct: 1347 EREEQPLRRQERDR---KFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE 1403
Query: 230 RERQREKDRDRQ 241
RE+Q +DRDR+
Sbjct: 1404 REQQLRQDRDRK 1415
Score = 89.0 bits (219), Expect = 4e-18
Identities = 61/218 (27%), Positives = 117/218 (53%), Gaps = 32/218 (14%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRE---RQRWR--DRDRKRERWG 112
RE+ +RE+E +R K R E +R ++ R +Q KRD+E R+RW + + +RE+
Sbjct: 443 REQRLKREQEERRDWLK-REEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQE 501
Query: 113 DRDRETETERQEERERQRDRKREKD-------------RERQRQREIGIDKDREIETEKD 159
R+++ E++E RE++ R+ E++ RE++ +RE + ++ E E++
Sbjct: 502 RREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQE 561
Query: 160 RDREREMGETERYRD----RERERQKQRETRRDRDRERQR---------EKEDRERDRDR 206
R +R E E RD RE ER++QR R +R QR E+E+R R +
Sbjct: 562 RREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLK 621
Query: 207 QKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAI 244
++E E++R ++ ++++ R ++ +RE+ R++ +
Sbjct: 622 REEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRL 659
Score = 88.2 bits (217), Expect = 7e-18
Identities = 66/221 (29%), Positives = 124/221 (56%), Gaps = 27/221 (12%)
Query: 48 RGSRVAPAIIRERERQ--RERERQRKRAKE--RHREKDREIEKDRDRQRKRDRER----- 98
R R +++ERE Q R +ER RK +E RH+E+ R+ ++ R R+++RER
Sbjct: 1336 RKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKE 1395
Query: 99 -QRWRDRDRKRERWGDRDRETETERQEERERQRDRK--------REKDRER---QRQREI 146
Q+ R ++R+++ DRDR+ E Q+ ++RDRK R ++RER + ++++
Sbjct: 1396 EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQL 1455
Query: 147 GIDKDREIETEKDRDREREMGETERY-RDRERERQKQRETRRDRDRE-RQREKEDRERDR 204
++ R+ E+ +ERE + R RDR+ ++Q+ R++RDR+ R++E +E +R
Sbjct: 1456 RQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPER 1515
Query: 205 ----DRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQ 241
+ Q+ + R R+ + + ++R +QR +DRDR+
Sbjct: 1516 KFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRK 1556
Score = 87.8 bits (216), Expect = 1e-17
Identities = 62/194 (31%), Positives = 113/194 (58%), Gaps = 19/194 (9%)
Query: 60 RERQRERERQRKRAKERHREK--DREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
RE+Q RE+Q +R +E RE+ R+ E++R +QR R ++ R R+++ +RE+ R+ E
Sbjct: 497 REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR-REQEERREQLLKREEE 555
Query: 118 T--ETERQEER-----ERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETE 170
E ER+E+R E +RD+ +++ ER++QR + +++E E+ RE E E
Sbjct: 556 KRLEQERREQRLKREQEERRDQLLKREEERRQQR---LKREQEERLEQRLKRE----EVE 608
Query: 171 RYRDRERERQK-QRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERD 229
R ER Q+ +RE + R++ + E++E R +Q RE+ RE+ R+ ++ER
Sbjct: 609 RLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL 668
Query: 230 RER-QREKDRDRQK 242
+R +RE + +R++
Sbjct: 669 EQRLKREHEEERRE 682
Score = 87.4 bits (215), Expect = 1e-17
Identities = 78/257 (30%), Positives = 135/257 (52%), Gaps = 28/257 (10%)
Query: 21 QLLLQTRPVSWRLA---MRSQIEDR----DVLILRGSRVAPAIIRERERQ-RERER--QR 70
QL Q R +RL +R Q ++R D LR + +ER+R+ RE E+ Q
Sbjct: 1571 QLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQE 1630
Query: 71 KRAKERHR-EKDREIEKDRDRQRKRDRERQRWRDRDRK-RE-------------RWGDRD 115
+ ++ HR E+DR+ ++ + R+++RE+Q DRDRK RE R +RD
Sbjct: 1631 REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD 1690
Query: 116 RETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDR 175
R+ E Q+ R ++R+RK ++ ++ R++E+ K RE E + + ++ ERYR
Sbjct: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQELE-RKFREEEQLRQETEQEQLRRQERYRKI 1749
Query: 176 ERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQRE 235
E Q + E + R ++R+++ RE ++ RQ ERE+ + R +E+ R +E ++RE
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQLRQ-EREEQQLRSQESDRKFREEEQLRQERE 1808
Query: 236 KDRDRQKAIDCVPGRWE 252
+ + R + D RWE
Sbjct: 1809 EQQLRPQQRD-GKYRWE 1824
Score = 85.9 bits (211), Expect = 4e-17
Identities = 56/186 (30%), Positives = 104/186 (55%), Gaps = 13/186 (6%)
Query: 66 RERQRKRAKERHREKDREIEKD---RDRQRKRDRERQ--RWRDRDRKRERWGDRDRETET 120
++R+++ + R +DR++E++ R RQ+++++ER+ ++ K+ER RDR+
Sbjct: 111 QDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQ--- 167
Query: 121 ERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQ 180
R EE RQR +E++ R + ++ K E E D ++ R E R E+Q
Sbjct: 168 RRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQ 227
Query: 181 KQRETRRDRDRERQREKEDRERD----RDRQKEREKDRYRERETGRDRDKERDRERQREK 236
+QR R+DR + + EKE R+R+ ++ +K +E++ R+RE + ++ R ERQ E
Sbjct: 228 QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ-EL 286
Query: 237 DRDRQK 242
R+RQ+
Sbjct: 287 RRERQE 292
Score = 85.9 bits (211), Expect = 4e-17
Identities = 49/186 (26%), Positives = 110/186 (59%), Gaps = 6/186 (3%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
RER + E E +R++ + R ++ RE E+ R+++ KR E +R + R R ++ RE
Sbjct: 485 RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQ---LRRE 541
Query: 118 TETERQEERERQRDRKREKDRERQR-QREIGIDKDREIETEKDRDREREMGETERYRDRE 176
E R++ +R+ +++ E++R QR +RE +D+ ++ E++R ++R E E ++
Sbjct: 542 QEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQR 601
Query: 177 RERQKQRETRRDRDRERQREKEDRERDRDRQ--KEREKDRYRERETGRDRDKERDRERQR 234
+R++ ++ RE++ ++E+ E +R +Q K E++ R+++ R++ + R++ +R
Sbjct: 602 LKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKR 661
Query: 235 EKDRDR 240
E++ +R
Sbjct: 662 EEEEER 667
Score = 85.9 bits (211), Expect = 4e-17
Identities = 48/207 (23%), Positives = 114/207 (55%), Gaps = 20/207 (9%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQ---------------RWR 102
RE+ R++ERERQ ++ K+ +++++ + ++ +++R+++RE++ R
Sbjct: 948 REKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREE 1007
Query: 103 DRDRKRERWGDRDRETETERQEERE---RQRDRKREKDRERQRQREIGIDKDREIETEKD 159
R+R+ W + R+ + +QEE + +R+++R ++RERQ + E + ++ E ++
Sbjct: 1008 REKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEE 1067
Query: 160 RDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRE--RDRDRQKEREKDRYRE 217
R+ R +YR E +Q++ + R+ +R+R++ +R+ + + Q+E E+ E
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127
Query: 218 RETGRDRDKERDRERQREKDRDRQKAI 244
RE R ++ ER + E ++ ++ +
Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLL 1154
Score = 85.9 bits (211), Expect = 4e-17
Identities = 59/226 (26%), Positives = 123/226 (54%), Gaps = 42/226 (18%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQ---------------RWRD 103
E+ R++ERERQ + +E +E+++ + ++R+++R+++ ERQ R
Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEP 1158
Query: 104 RDRKRERWGDRDRETETERQEE----RERQRDRKREKDRERQRQREIGIDKDREIETEKD 159
R+R+ + RE E +QEE RE Q R++E++R+ + + E+ K ++ ++D
Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDED 1218
Query: 160 R----------DREREMGETERY-RDRERERQKQRETRRDRDRERQR-------EKEDRE 201
+ ++E + + + Y + RE E+ +Q E + RDR+ Q+ E+++R+
Sbjct: 1219 QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD 1278
Query: 202 RDRDRQKEREKDRYRERETGRDRD-----KERDRERQREKDRDRQK 242
R+++R++ +++DR+ E +R+ K RDR+ Q EK R++
Sbjct: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE 1324
Score = 85.9 bits (211), Expect = 4e-17
Identities = 59/211 (27%), Positives = 121/211 (57%), Gaps = 21/211 (9%)
Query: 47 LRGSRVAPAIIRERERQRERERQRKRAKE----RHREKDREIEKDRDRQRKRDRERQRWR 102
LR + E +R R +ER+RK KE R +E+++++ +DRDR+ + + ++ +
Sbjct: 1367 LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQ 1426
Query: 103 DRDRKRERWGDRDRETETERQEERER---QRDRKREKDRERQRQREIGIDKDREIETEKD 159
+RDRK R+ E + RQ ERER + +++ ++R R+ + E + ++RE +
Sbjct: 1427 ERDRK-----FREEEQQVRRQ-ERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHR 1480
Query: 160 RDRERE-MGETERYRDRERERQKQRETRRDRDRER---QREKEDRERDRDRQKEREKDRY 215
++R+R+ + E ++ R +ER+R+ + + R ++ ER + E++ + R R+ +E+ +
Sbjct: 1481 QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQL 1540
Query: 216 RERETGRDRDKERDR----ERQREKDRDRQK 242
R +E G+ R ++RDR E Q ++R+ Q+
Sbjct: 1541 RRQERGQQRRQDRDRKFREEEQLRQEREEQQ 1571
Score = 85.1 bits (209), Expect = 6e-17
Identities = 57/196 (29%), Positives = 111/196 (56%), Gaps = 15/196 (7%)
Query: 58 RERERQRERE--RQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRK-RERWGDR 114
R+R+ Q E++ R+ + K R +E DR+ ++ ++R+ + R ++RDRK RE +
Sbjct: 1310 RDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE---EE 1366
Query: 115 DRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRD---REREMGETER 171
R E R+ E QR R++E++R+ ++ + ++RE + +DRD RE E + +
Sbjct: 1367 LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQ 1426
Query: 172 YRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDR- 230
RDR+ ++Q+ R++R+R+ E++ ++R R+ E+ +ERE + +ERDR
Sbjct: 1427 ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRK 1486
Query: 231 -----ERQREKDRDRQ 241
++ R ++RDR+
Sbjct: 1487 FLEEEQQLRRQERDRK 1502
Score = 84.7 bits (208), Expect = 8e-17
Identities = 55/216 (25%), Positives = 117/216 (54%), Gaps = 31/216 (14%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQ---------------RWR 102
RE R++E ERQ ++ +E +E+++ + ++ +++R+++RERQ R
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127
Query: 103 DRDRKRERWGDRDRETETERQEERERQRD---RKREKDRERQRQREIGIDKDREIETEKD 159
R+R+ + RE E +QEE + R+ ++R ++ ERQ + E + ++ E ++
Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187
Query: 160 RDREREMGETERYRDRERERQKQRETRRDRDRER------QREKEDRERDRDRQ-KEREK 212
+++ R+ E + + E +RQK+++ RD D+ + EKE+ RD K RE
Sbjct: 1188 QEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGREN 1247
Query: 213 DRYRERETGRDRDKERDRE------RQREKDRDRQK 242
+++R+ E + RD++ ++ Q+E+DR++++
Sbjct: 1248 EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQER 1283
Score = 84.3 bits (207), Expect = 1e-16
Identities = 62/240 (25%), Positives = 129/240 (53%), Gaps = 35/240 (14%)
Query: 36 RSQIEDRDVLILRGSRVAPAIIRERERQR----ERERQRKRAKERHREKDREIEKDRDRQ 91
R ++ R L + R A R++ QR E E++++R + R REK+ + ++ ++
Sbjct: 781 RQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL 840
Query: 92 RKRDRERQRWR-------DRDRKRERWGDRDRETETERQEERERQRDRKREKD--RERQR 142
++R+R +Q D++R+R + RD++ + +EER+R+R K +E+ R
Sbjct: 841 QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR 900
Query: 143 QREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQ-------RETRRDRDRERQR 195
+ + + ++ E ++R++ R + +YR+ E+ +Q++ RE RR ++RERQ
Sbjct: 901 KEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQY 960
Query: 196 EKEDR-----------ERDRDRQKEREKDRYRERETGRDRDKE---RDRERQREKDRDRQ 241
K+ + E ++ R++EREK +YRE E + +++ +RE++R ++ +RQ
Sbjct: 961 RKDKKLQQKEEQLLGEEPEKRRRQEREK-KYREEEELQQEEEQLLREEREKRRRQEWERQ 1019
Score = 83.6 bits (205), Expect = 2e-16
Identities = 60/220 (27%), Positives = 120/220 (54%), Gaps = 37/220 (16%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
E+ R++ERE++ + +E +E+++ + ++R+++R+++ ERQ + + ++E E
Sbjct: 979 EKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER 1038
Query: 119 ETERQEERERQ------------------RDRKREKDRERQRQREIGIDKDRE----IET 156
E R +ERERQ R+ +R ++ ERQ ++E + ++ E E
Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098
Query: 157 EKDRDRERE---MGETERYRDRERERQKQRETRRDRDRERQ-REKED---------RERD 203
EK R +ERE E E ++ E+ +++RE RR ++ ERQ RE+E+ RE
Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEP 1158
Query: 204 RDRQKEREKDRYRERETGRDRDKE--RDRERQREKDRDRQ 241
R+++ + +YRE E + +++ R+ + +R ++R+RQ
Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQ 1198
Score = 83.6 bits (205), Expect = 2e-16
Identities = 53/194 (27%), Positives = 110/194 (56%), Gaps = 13/194 (6%)
Query: 58 RERERQRERERQRKRAKER----HREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGD 113
+ERE+Q ++R RK +E +E+DR+ ++ + R+++RER+ + + R+
Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHR 1461
Query: 114 RDRETETERQEERERQRDRKREKDR-----ERQRQREIGIDKDREIETEKDRDREREMGE 168
+ RE E + +ERE Q+ ++E+DR E+Q +R+ ++DR+ ++ R +E E
Sbjct: 1462 KFRE-EEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ---ERDRKFREQELRSQEPERKF 1517
Query: 169 TERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKER 228
E + R++++++ + ++ RQ + R +DRDR+ E+ +ERE + +ER
Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577
Query: 229 DRERQREKDRDRQK 242
DR+ + E+ + R++
Sbjct: 1578 DRKFRLEEQKVRRQ 1591
Score = 83.6 bits (205), Expect = 2e-16
Identities = 58/204 (28%), Positives = 115/204 (56%), Gaps = 20/204 (9%)
Query: 58 RERERQ-RERERQRKRAKERHREKDREIEKD--RDRQRKRDRERQRWRDRDRKRERWGDR 114
RE E+Q R +ER+RK +E + + +E+E+ + Q +++ E+++ R ++R R+ +
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEE 1753
Query: 115 DRETETERQEERERQRDRK-REKDRERQRQREIGI---DKDREIETEKDRDREREMGETE 170
E E Q+ R ++RDRK RE+++ RQ + E + + DR+ E+ +ERE +
Sbjct: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLR 1813
Query: 171 ------RYRDRERERQ-KQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRD 223
+YR E + Q +++E R ++R+RQ E++ +++ + E++ ++E E R
Sbjct: 1814 PQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRR 1873
Query: 224 RDKERD------RERQREKDRDRQ 241
+++ER R +Q+E+ R RQ
Sbjct: 1874 QERERKLREEHIRRQQKEEQRHRQ 1897
Score = 83.2 bits (204), Expect = 2e-16
Identities = 57/191 (29%), Positives = 109/191 (57%), Gaps = 20/191 (10%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQR-WRD-----RDRKRERWG 112
E+ R++E ERQ + +E +E+++ + R+ Q KR +ER+R +R+ R ++++R+
Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLL---REEQEKRRQERERQYREEEELQRQKRKQRYR 1215
Query: 113 DRDRETETERQEERERQ---RDRK---REKDRERQRQREIGIDKDREIETEKDRDREREM 166
D D+ ++ + Q E E++ RD K + ++ E+ RQ E +DR + +D + +
Sbjct: 1216 DEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDR----QSQQDLQHLL 1271
Query: 167 GE-TERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRD 225
GE ER R++ER R +QR+ + + +RE++ + RDR+ + EK RE + R
Sbjct: 1272 GEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRR 1331
Query: 226 KERDRERQREK 236
+E DR+ + E+
Sbjct: 1332 QETDRKFREEE 1342
Score = 83.2 bits (204), Expect = 2e-16
Identities = 55/201 (27%), Positives = 123/201 (61%), Gaps = 19/201 (9%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDR--------KRE 109
RE E+ R+ E + R ++ ++ + + ++R R+ +ER+RW+ RDR +RE
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDRE--QERRRWQQRDRHFPEEEQLERE 1302
Query: 110 RWGD---RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREM 166
+ RDR+++ E+Q RE + +++R ++ +R+ + E + ++RE + + ++R+R+
Sbjct: 1303 EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKF 1362
Query: 167 GETE-RYRDRERERQKQRETRRDRDRERQREKEDRE---RDRDRQKEREKDR-YRERETG 221
E E R++++ R+ ++ + R ++RER+ KE+++ ++R++Q +++DR +RE E
Sbjct: 1363 REEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQ 1422
Query: 222 RDRDKERDRERQREKDRDRQK 242
R +ERDR+ + E+ + R++
Sbjct: 1423 LSR-QERDRKFREEEQQVRRQ 1442
Score = 82.8 bits (203), Expect = 3e-16
Identities = 58/224 (25%), Positives = 107/224 (47%), Gaps = 45/224 (20%)
Query: 60 RERQRERERQRKRAKERHREKDR---EIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
RE+Q RE++ KR +E R + R E E++R Q + E+++ R+R + R
Sbjct: 649 REQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQL 708
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRD-- 174
E+E + ++ + R RK+E R RQ Q E ++ E++ +++ R+ E E+ RD
Sbjct: 709 ESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFT 768
Query: 175 -----------------------RERERQKQRETRRDRDRERQREKEDRERDRDRQKERE 211
+RERQ + E R+ R++ E+E++E+ R +++ERE
Sbjct: 769 WQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRERE 828
Query: 212 KD-----------------RYRERETGRDRDKERDRERQREKDR 238
K+ + +E E G D+ER R +++ +D+
Sbjct: 829 KELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872
Score = 82.8 bits (203), Expect = 3e-16
Identities = 53/204 (25%), Positives = 106/204 (51%), Gaps = 21/204 (10%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRE---RWGD- 113
RE E ++ E Q R ++ R ++RE + + + +R + +QR+RD D++ + +W
Sbjct: 1171 REEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPE 1230
Query: 114 ------------RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRD 161
+ RE E RQ E + RDR+ ++D + + ++DRE E + +
Sbjct: 1231 KENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQ--QERDREQERRRWQQ 1288
Query: 162 REREMGETERYRDRERERQKQRETRRDRDRE---RQREKEDRERDRDRQKEREKDRYRER 218
R+R E E+ E++ K+R+ + +++ +RE++ R ++ DR+ E+ +ER
Sbjct: 1289 RDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQER 1348
Query: 219 ETGRDRDKERDRERQREKDRDRQK 242
E R +ERDR+ + E+ R +++
Sbjct: 1349 EEQPLRRQERDRKFREEELRHQEQ 1372
Score = 81.6 bits (200), Expect = 7e-16
Identities = 57/225 (25%), Positives = 130/225 (57%), Gaps = 41/225 (18%)
Query: 58 RERERQ-----RERERQRKRAKERHREKDREIEKDRDRQRKRDRER-QRWR---DRDRKR 108
RERE++ E + QR+ ++ +E++ +++D++R+R +++ R Q+WR + +RKR
Sbjct: 825 REREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKR 884
Query: 109 ERWG-----------DRDRETETERQEERERQ-RDRKREKDRERQRQREIGIDKDREIET 156
R ++++ E +EE +R+ R+++R +++ERQ + E + ++ E
Sbjct: 885 RRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944
Query: 157 EKDRDREREMGETERYRDRERERQKQR-------ETRRDRDRERQ-REKEDRERDRDR-- 206
++R++ R +YR ++ +QK+ E RR ++RE++ RE+E+ +++ ++
Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
Query: 207 QKEREKDR-------YRERETGRDRDKE---RDRERQREKDRDRQ 241
++EREK R YR+++ + +++ +RE++R ++R+RQ
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQ 1049
Score = 80.1 bits (196), Expect = 2e-15
Identities = 65/240 (27%), Positives = 119/240 (49%), Gaps = 28/240 (11%)
Query: 24 LQTRPVSWRLAMRSQIEDRDVLILRGSRVAPAIIRERER-QRERERQR----KRAKERHR 78
LQ R S + R Q E R+ L+ R R +R +RE+E +R KR +ER +
Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQ 587
Query: 79 EKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQ-----EERERQRDRK 133
++ + +++R QR + E +R +R+ +R + E E +Q E+ ER++ +
Sbjct: 588 QRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQL 647
Query: 134 REKDRERQRQREIGIDKDREIETEKDRD-----REREMGETERYRDRER----------E 178
R + +ER+ QR +++ +E R+ RE+E+ E E+ + RER +
Sbjct: 648 RREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQ 707
Query: 179 RQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDR 238
+ + + R+ + R R++E + R RQ++ EK R RE E ++ R++Q E+ R
Sbjct: 708 LESEADARQSKVYSRPRKQEGQRR---RQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Score = 80.1 bits (196), Expect = 2e-15
Identities = 66/243 (27%), Positives = 122/243 (50%), Gaps = 48/243 (19%)
Query: 48 RGSRVAPAIIRERERQR--ERERQRKRAKE----RHREKDREIEKD-------------- 87
R R +++ERE Q+ +ER RK +E R +E+DR+ +
Sbjct: 1461 RKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEE 1520
Query: 88 ------RDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQ--EERERQRDRKREKDRE 139
+ RQRK +E Q+ R ++R ++R DRDR+ E Q +ERE Q+ ++E+DR+
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK 1580
Query: 140 -RQRQREIGIDKDREIETEKDRDREREMGETERYRDRER----------ERQKQRETRRD 188
R ++++ + E ++ R+ G+ + ++R+R ER++Q+ R++
Sbjct: 1581 FRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE 1640
Query: 189 RDRE---------RQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRD 239
RDR+ RQ ++ DRDR+ E+ +E E + R +ERDR+ + E+ +
Sbjct: 1641 RDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQL 1700
Query: 240 RQK 242
R++
Sbjct: 1701 RRQ 1703
Score = 80.1 bits (196), Expect = 2e-15
Identities = 57/220 (25%), Positives = 120/220 (54%), Gaps = 36/220 (16%)
Query: 58 RERE-RQRERERQRKRAKERHR-EKDREIEKDRDRQRKRDRERQRWRDRDRKRERWG--- 112
R+R+ R+ E+ RQ + ++ R E+DR+ + + R++++ER+ D + R + G
Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612
Query: 113 ---DRDRETETERQ--EERERQRDRKREKDRE----------RQRQREIGIDKDREIETE 157
+RDR+ + Q +ERE Q+ ++E+DR+ ++R++++ D+DR+ E
Sbjct: 1613 LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE 1672
Query: 158 KD------------RDREREMGETE-RYRDRERER---QKQRETRRDRDRERQREKEDRE 201
+ ++R+R+ E E + R +ERER Q++++ RR + RE+E
Sbjct: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLR 1732
Query: 202 RDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQ 241
++ ++++ R ++RYR+ ER+ ++ R ++RDR+
Sbjct: 1733 QETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRK 1772
Score = 79.7 bits (195), Expect = 3e-15
Identities = 54/196 (27%), Positives = 111/196 (56%), Gaps = 20/196 (10%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
ER+R+R + +E+ R++ + ++++ + ++ +RE++R ++++R+ RE
Sbjct: 881 ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQY-------REE 933
Query: 119 ETERQEERE---RQRDRKREKDRERQRQREIGIDKDRE----IETEKDRDRERE---MGE 168
E +QEE + +R+++R ++RERQ +++ + + E E EK R +ERE E
Sbjct: 934 EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE 993
Query: 169 TERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQ---KEREKDRYRERETGRDRD 225
E ++ E+ +++RE RR ++ ERQ K+D + + Q +EREK R +ERE +
Sbjct: 994 EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE 1053
Query: 226 KERDRERQREKDRDRQ 241
+E +E ++ +R+
Sbjct: 1054 EELQQEEEQLLGEERE 1069
Score = 79.3 bits (194), Expect = 3e-15
Identities = 60/264 (22%), Positives = 137/264 (51%), Gaps = 47/264 (17%)
Query: 24 LQTRPVSWRLAMRSQIEDRDVLILRGSRVAPAIIR-----ERERQRERERQRKRAKERHR 78
+++R W+ + S+ + R + R R E+ R+RE E Q + + HR
Sbjct: 697 IKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHR 756
Query: 79 EKDREIEK-------------DRDRQR-------KRDRERQ-RWRDRDRKRERWGDRDRE 117
++ E ++ +R RQR + RERQ R +R ++ +R+ + E
Sbjct: 757 QQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEE 816
Query: 118 TETERQEERERQRD----RKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173
E R++ RER+++ + E+ + R+R +++ ++D ++ +++R R +E +++R
Sbjct: 817 KEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEED-GLQEDQERRRSQEQRRDQKWR 875
Query: 174 ---DRERERQK---------QRETRRDRDRERQREKEDRERDRDRQKEREKDR-YRERET 220
+ ER+R++ Q + R+++ ++ E+E + +R++++ +E++R YRE E
Sbjct: 876 WQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQ 935
Query: 221 GRDRDKE---RDRERQREKDRDRQ 241
+ +++ +RE++R ++R+RQ
Sbjct: 936 LQQEEEQLLREEREKRRRQERERQ 959
Score = 79.3 bits (194), Expect = 3e-15
Identities = 55/233 (23%), Positives = 130/233 (55%), Gaps = 28/233 (12%)
Query: 25 QTRPVSWRLAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREI 84
Q R +W+ Q E++ + P + +RERQ E +++R ++R ++ E
Sbjct: 763 QRRDFTWQW----QAEEKSERGRQRLSARPPLREQRERQLRAEERQQR-EQRFLPEEEEK 817
Query: 85 EKDRDRQRKRDRERQRWRDRDR--KRERWGDRDRETETERQEERERQRDRKREKDR---- 138
E+ R ++R+R++E Q + ++ +RER + +E E QE++ER+R +++ +D+
Sbjct: 818 EQRRRQRREREKELQFLEEEEQLQRRER-AQQLQEEEDGLQEDQERRRSQEQRRDQKWRW 876
Query: 139 ----ERQRQR---------EIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRET 185
ER+R+R + + K++++ E++ + +RE E R +++ER+ +++ +
Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936
Query: 186 RRDRD---RERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQRE 235
+++ + RE + ++ +ER+R +K+++ + E+ G + +K R +ER+++
Sbjct: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKK 989
Score = 79.3 bits (194), Expect = 3e-15
Identities = 55/197 (27%), Positives = 109/197 (55%), Gaps = 20/197 (10%)
Query: 58 RERERQRERERQRKRAKE------------RHREKDREIEKDRDRQRKRDRERQRWRDRD 105
+ERE+Q +R RK +E R +E+DR+ ++ + R+++RER+ ++
Sbjct: 1655 QEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ 1714
Query: 106 RKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRERE 165
+ R + + +R+ E Q +E ++++ R ++R R+ E + +RE + + ++R+R+
Sbjct: 1715 QLRRQ--ELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRK 1772
Query: 166 MGETERYRDRERERQKQRETRRDRD-RERQREKEDRERDRDRQKEREKDRYRERETGRDR 224
E E+ R +ERE Q+ R DR RE ++ +++RE + R ++R+ +YR E
Sbjct: 1773 FREEEQLR-QEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRD-GKYRWEEEQLQL 1830
Query: 225 DKERDRERQREKDRDRQ 241
+++ R RQ +RDRQ
Sbjct: 1831 EEQEQRLRQ---ERDRQ 1844
Score = 78.6 bits (192), Expect = 6e-15
Identities = 50/196 (25%), Positives = 113/196 (57%), Gaps = 13/196 (6%)
Query: 58 RERERQRERERQRKRAKERHRE-KDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
+ER+R+ E Q+ R +ER R+ + E + ++R RK E Q ++R+ ++ +RDR
Sbjct: 1426 QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR 1485
Query: 117 ETETERQEERERQRDRK-REKDRERQRQREIGIDKDREIE---------TEKDRDREREM 166
+ E Q+ R ++RDRK RE++ Q +++++++ E+ + R +E
Sbjct: 1486 KFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER 1545
Query: 167 GETERYRDRERERQKQRETRRDRDRER-QREKEDRERDRDRQKEREKDRYRERETGRDRD 225
G+ +R +DR+R+ +++ + R++R+ ++ R++ DR+ + QK R +++ R+ +
Sbjct: 1546 GQ-QRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQL 1604
Query: 226 KERDRERQREKDRDRQ 241
+ ++ ++Q ++RDR+
Sbjct: 1605 RRQEGQQQLRQERDRK 1620
Score = 78.2 bits (191), Expect = 8e-15
Identities = 68/240 (28%), Positives = 128/240 (53%), Gaps = 34/240 (14%)
Query: 24 LQTRPVSWRLAMRSQIE-DRDVLILRGSRVAPAIIRERERQ--RERERQRKRAKE----R 76
L+ P R Q+ DRD R R +++E E Q R +ER RK +E R
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRD----RKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLR 1701
Query: 77 HREKDREIEKDRDRQRKRDRERQRWRDRDRKRE-------RWGDRDRETETERQEERERQ 129
+E++R+ ++ + R+++ ER ++R+ ++ R+ R +R R+ E Q ER+
Sbjct: 1702 RQERERKFLQEEQQLRRQELER-KFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760
Query: 130 RDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRD- 188
+ R ++R+R+ + E + ++RE + + ++ +R+ E E+ R +ERE Q+ R +RD
Sbjct: 1761 EQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLR-QEREEQQLRPQQRDG 1819
Query: 189 --RDRERQREKEDRE----RDRDRQ-------KEREKDRYRERETGRDRDKERDRERQRE 235
R E Q + E++E ++RDRQ +EK R E+E ++ +++R +ER+R+
Sbjct: 1820 KYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERK 1879
Score = 77.8 bits (190), Expect = 1e-14
Identities = 47/228 (20%), Positives = 118/228 (51%), Gaps = 9/228 (3%)
Query: 25 QTRPVSWRLAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREI 84
Q R WR + + + R + + + +E++ +E E + +R + R + +
Sbjct: 868 QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE 927
Query: 85 EKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQR 144
+ R+ ++ + E Q R+ KR R +R+R+ +++ +++ ++ E ++ R+++R
Sbjct: 928 RQYREEEQLQQEEEQLLREEREKRRRQ-ERERQYRKDKKLQQKEEQLLGEEPEKRRRQER 986
Query: 145 EIGIDKDREIETE------KDRDREREMGETERYRDRERERQKQRE-TRRDRDRERQREK 197
E ++ E++ E ++R++ R +YR ++ +Q++ + R +R++ R +E+
Sbjct: 987 EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
Query: 198 EDRERDRDR-QKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAI 244
E + R+ + Q+E E+ ERET R ++ ER ++ E ++ ++ +
Sbjct: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL 1094
Score = 77.8 bits (190), Expect = 1e-14
Identities = 50/224 (22%), Positives = 123/224 (54%), Gaps = 31/224 (13%)
Query: 38 QIEDRDVLILRGSRVAPAIIRERERQRER--------------------ERQRKRAKERH 77
Q++ + +LR R + R ++RER E++R++ +E+
Sbjct: 935 QLQQEEEQLLREERE-----KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKK 989
Query: 78 REKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREK- 136
++ E++++ ++ + +RE++R ++ +R+ + + +E E +EERE++R ++RE+
Sbjct: 990 YREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQ 1049
Query: 137 ---DRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRER 193
+ E Q++ E + ++RE ++ +R+ E E ++ E+ +++ E RR ++RER
Sbjct: 1050 YREEEELQQEEEQLLGEERETRRRQELERQYRK-EEELQQEEEQLLREEPEKRRRQERER 1108
Query: 194 Q-REKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREK 236
Q RE+E+ +++ ++ E+++ R +E R +E + +++ E+
Sbjct: 1109 QCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQ 1152
Score = 77.8 bits (190), Expect = 1e-14
Identities = 57/219 (26%), Positives = 112/219 (51%), Gaps = 36/219 (16%)
Query: 59 ERERQRERERQRKRAKE----RHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDR 114
E E+Q +ER RK +E + RE+ + ++RDR+ + ++ R ++RDRK R
Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELR 1509
Query: 115 DRETE--------------------TERQEERERQRDRKREKDRERQRQREIGIDKDREI 154
+E E E Q+ R ++R ++R +DR+R+ + E + ++RE
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569
Query: 155 ETEKDRDREREMG-ETERYRDRERER---QKQRETRRDRDRERQREKEDRERDRDRQKER 210
+ ++R+R+ E ++ R +E+ER + +++ RR +++ R++ DR+ D Q +
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629
Query: 211 EKDRYRERETGRDRD--------KERDRERQREKDRDRQ 241
E++ + RDR + ++RE+Q DRDR+
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRK 1668
Score = 75.9 bits (185), Expect = 4e-14
Identities = 62/243 (25%), Positives = 127/243 (52%), Gaps = 43/243 (17%)
Query: 36 RSQIEDRDVLILRGS---RVAPAIIRERERQR--------ERERQRKRAKERHREKDREI 84
R Q E R+ + R R+ + RE E +R E+E+ R+R K R + ++
Sbjct: 649 REQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQL 708
Query: 85 EKDRD--------RQRKRDRERQRWRDRDRKRER------WGDRDRETETERQEERER-- 128
E + D R RK++ +R+R ++++ KR R W + +R +++EE+ R
Sbjct: 709 ESEADARQSKVYSRPRKQEGQRRR-QEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDF 767
Query: 129 ----QRDRKREKDRERQRQR-EIGIDKDREIETEKDRDREREMGETERYRDRERERQKQR 183
Q + K E+ R+R R + ++R++ E+ + RE +R+ E E++++R
Sbjct: 768 TWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQRE------QRFLPEEEEKEQRR 821
Query: 184 ETRRDRDRERQ---REKEDRERDRDRQKEREKDRYRE-RETGRDRDKERDRERQREKDRD 239
RR+R++E Q E++ + R+R +Q + E+D +E +E R +++ RD++ + + + +
Sbjct: 822 RQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEE 881
Query: 240 RQK 242
R++
Sbjct: 882 RKR 884
Score = 75.5 bits (184), Expect = 5e-14
Identities = 58/204 (28%), Positives = 111/204 (54%), Gaps = 21/204 (10%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEK--DRDRQRKRDRERQRWRDRDRKRERWGDRD 115
+ER +QR ++R RK +E ++RE ++ ++R RK E Q+ R ++++R+ D
Sbjct: 1543 QERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQ 1602
Query: 116 RETETERQEERERQRDRKREKD----RERQRQREIGIDKDR------------EIETEKD 159
+ E Q++ ++RDRK +D +ER+ Q+ ++DR E E +
Sbjct: 1603 QLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR 1662
Query: 160 RDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERE 219
DR+R+ E E+ +E E Q+ R RDR + R+ E++ R ++R+R+ +E+ + R +E
Sbjct: 1663 HDRDRKFREEEQLL-QEGEEQQLRRQERDR-KFREEEQQLRRQERERKFLQEEQQLRRQE 1720
Query: 220 TGRD-RDKERDRERQREKDRDRQK 242
R R++E+ R+ ++ RQ+
Sbjct: 1721 LERKFREEEQLRQETEQEQLRRQE 1744
Score = 73.2 bits (178), Expect = 2e-13
Identities = 45/191 (23%), Positives = 114/191 (59%), Gaps = 11/191 (5%)
Query: 47 LRGSRVAPAIIRERERQRERERQRKRAKERHRE--KDREIEKDRDRQRKRDRERQR-WRD 103
LR + E + ++E E+++ R +ER+R+ ++ ++ +R+ Q+ R +ER R +R+
Sbjct: 1716 LRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE 1775
Query: 104 RDR-KRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGI---DKDREIETEKD 159
++ ++ER + R E++R+ E Q ++RE+ + R +QR+ ++ ++E ++
Sbjct: 1776 EEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQ 1835
Query: 160 R---DREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYR 216
R +R+R+ E++ +E+ R++++E ++ +++R++E+E + R+ + + ++K+ R
Sbjct: 1836 RLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLRE-EHIRRQQKEEQR 1894
Query: 217 ERETGRDRDKE 227
R+ G + +E
Sbjct: 1895 HRQVGEIKSQE 1905
Score = 62.0 bits (149), Expect = 6e-10
Identities = 39/160 (24%), Positives = 89/160 (55%), Gaps = 6/160 (3%)
Query: 40 EDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQ 99
++R IL ++ P ++ R++ER+R+ + ++ +E++ + + ++ RK E Q
Sbjct: 1743 QERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQ 1802
Query: 100 RWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKD 159
++R+ ++ R RD + E ++ + +++++ ++R+RQ + E ++ EK
Sbjct: 1803 LRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAE-----EQFATQEKS 1857
Query: 160 RDREREM-GETERYRDRERERQKQRETRRDRDRERQREKE 198
R E+E+ E E+ R +ERER+ + E R + +E QR ++
Sbjct: 1858 RREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQ 1897
Score = 55.5 bits (132), Expect = 5e-08
Identities = 37/151 (24%), Positives = 77/151 (50%), Gaps = 21/151 (13%)
Query: 105 DRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRER 164
+ KR R ++ + RQEE D++R + R+RQ + E G + +K +++ER
Sbjct: 97 EEKRARCDGKESLLQDRRQEE-----DQRRFEPRDRQLEEEPG-----QRRRQKRQEQER 146
Query: 165 EMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKER-------EKDRYRE 217
E+ E E +++ +++ RRD + RQR++ +R ++E+ E + + +
Sbjct: 147 ELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPD 206
Query: 218 RETGRDRD----KERDRERQREKDRDRQKAI 244
E R R+ + + RE ++++ R+RQ +
Sbjct: 207 EEQLRRRELLELRRKGREEKQQQRRERQDRV 237
Score = 40.0 bits (92), Expect = 0.002
Identities = 25/101 (24%), Positives = 55/101 (54%), Gaps = 10/101 (9%)
Query: 147 GIDKDREIETEKD----RDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRER 202
G+D+++ + +DR +E + R+ R+R+ +++ RR + R+ Q +
Sbjct: 94 GLDEEKRARCDGKESLLQDRRQEEDQ-RRFEPRDRQLEEEPGQRRRQKRQEQERELAEGE 152
Query: 203 DRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKA 243
++ ++ER + R R+R RD+E R+RQ ++R+ ++A
Sbjct: 153 EQSEKQERLEQRDRQR-----RDEELWRQRQEWQEREERRA 188
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 101 bits (251), Expect = 9e-22
Identities = 61/180 (33%), Positives = 97/180 (53%), Gaps = 23/180 (12%)
Query: 66 RERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWR-DRDRKRERWGDRDRETETERQE 124
+E+ RKR +E R D ++K++ + +R++ER+R R +R+RKR R E +
Sbjct: 231 KEKLRKRTEEPDR--DERLKKEKQEREEREKEREREREERERKRRR---------EEEER 279
Query: 125 ERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRE 184
E+ER RDR+R K R R R R DR +D +R R RER R + R+
Sbjct: 280 EKERARDRERRK-RSRSRSRHSSRTSDRRCSRSRDH---------KRSRSRERRRSRSRD 329
Query: 185 TRRDRDRER-QREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKA 243
RR R +R +R+ R RDR R K R++ Y+ R RDR+++R + + ++ D +K+
Sbjct: 330 RRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKS 389
Score = 100 bits (250), Expect = 1e-21
Identities = 60/203 (29%), Positives = 99/203 (48%), Gaps = 21/203 (10%)
Query: 32 RLAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQ 91
+L R++ DRD + +E++ + ERE++R+R +E K R E++R+++
Sbjct: 233 KLRKRTEEPDRD----------ERLKKEKQEREEREKEREREREERERKRRREEEEREKE 282
Query: 92 RKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKD 151
R RDRER R R R R R R + R + +R R R+R + R R R+R D+
Sbjct: 283 RARDRER---RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRS 339
Query: 152 REIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQ-REKEDRERDRDRQKER 210
+ RDR R + R+R+ K R RDR+++R+ +EKE R D + +
Sbjct: 340 ERKHRSRSRDRRRS-------KSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVK 392
Query: 211 EKDRYRERETGRDRDKERDRERQ 233
R ++ E KE D + +
Sbjct: 393 SGSREKQSEDTNTESKESDTKNE 415
Score = 95.5 bits (236), Expect = 5e-20
Identities = 62/188 (32%), Positives = 97/188 (51%), Gaps = 19/188 (10%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
+R+ + ++E+Q + +E+ RE++RE + + R+ + +RE++R RDR+R R+R R R +
Sbjct: 242 DRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRER-RKRSRSRSRHS 300
Query: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERE 178
R RD KR + RER+R R +DR R R +ER + R R
Sbjct: 301 SRTSDRRCSRSRDHKRSRSRERRRSRS------------RDRRRSRSHDRSER-KHRSRS 347
Query: 179 RQKQRETRRDRDRERQREKE-DRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKD 237
R ++R RDR + R K DRE+DR + KE+EK R + + K RE+Q E
Sbjct: 348 RDRRRSKSRDRKSYKHRSKSRDREQDR-KSKEKEK---RGSDDKKSSVKSGSREKQSEDT 403
Query: 238 RDRQKAID 245
K D
Sbjct: 404 NTESKESD 411
Score = 80.5 bits (197), Expect = 2e-15
Identities = 50/161 (31%), Positives = 81/161 (50%), Gaps = 39/161 (24%)
Query: 102 RDRDRKRERWGDRDRETETERQEERERQRDRKREKD-RERQRQREIGIDKDREIETEKDR 160
+++ RKR DRD + E+QE ER+++R+RE++ RER+R+RE
Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRRE--------------- 275
Query: 161 DREREMGETERYRDRERERQKQRETR---------------RDRDRERQREKE-DRERDR 204
E ER ++R R+R++++ +R R RD +R R +E R R R
Sbjct: 276 -------EEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSR 328
Query: 205 DRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAID 245
DR++ R DR + R RD+ R + R R+ + R K+ D
Sbjct: 329 DRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRD 369
Score = 78.6 bits (192), Expect = 6e-15
Identities = 49/135 (36%), Positives = 70/135 (51%), Gaps = 17/135 (12%)
Query: 123 QEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRD---RERER 179
+E +E+ R R E DR+ + ++E K E EK+R+RERE E +R R+ RE+ER
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKE----KQEREEREKEREREREERERKRRREEEEREKER 283
Query: 180 QKQRETRRDRDRERQRE---------KEDRERDRDRQKEREKDRYRERETGRDRDKERDR 230
+ RE RR R R R R R+ R R +ER + R R+R R D+ +
Sbjct: 284 ARDRE-RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK 342
Query: 231 ERQREKDRDRQKAID 245
R R +DR R K+ D
Sbjct: 343 HRSRSRDRRRSKSRD 357
Score = 71.2 bits (173), Expect = 9e-13
Identities = 50/165 (30%), Positives = 73/165 (44%), Gaps = 30/165 (18%)
Query: 58 RERERQRERERQ-RKRAKERH--REKDREIEKDRD----------RQRKRDRERQRWRDR 104
RE+ER R+RER+ R R++ RH R DR + RD R R RDR R R DR
Sbjct: 279 REKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR 338
Query: 105 DRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRER 164
++ R RDR R + RDRK K R + R RE + K +++E+
Sbjct: 339 SERKHRSRSRDR--------RRSKSRDRKSYKHRSKSRDRE---------QDRKSKEKEK 381
Query: 165 EMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKE 209
+ ++ + R+KQ E +E + E D + E
Sbjct: 382 RGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
Score = 53.1 bits (126), Expect = 3e-07
Identities = 30/80 (37%), Positives = 54/80 (67%), Gaps = 3/80 (3%)
Query: 163 EREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGR 222
++ MG + E ++K R+ + DR+ + +KE +ER+ +R+KERE++R ERE R
Sbjct: 215 KQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQERE-EREKERERER-EERERKR 272
Query: 223 DRDKERDRERQREKDRDRQK 242
R++E +RE++R +DR+R+K
Sbjct: 273 RREEE-EREKERARDRERRK 291
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 101 bits (251), Expect = 9e-22
Identities = 61/180 (33%), Positives = 97/180 (53%), Gaps = 23/180 (12%)
Query: 66 RERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWR-DRDRKRERWGDRDRETETERQE 124
+E+ RKR +E R D ++K++ + +R++ER+R R +R+RKR R E +
Sbjct: 231 KEKLRKRTEEPDR--DERLKKEKQEREEREKEREREREERERKRRR---------EEEER 279
Query: 125 ERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRE 184
E+ER RDR+R K R R R R DR +D +R R RER R + R+
Sbjct: 280 EKERARDRERRK-RSRSRSRHSSRTSDRRCSRSRDH---------KRSRSRERRRSRSRD 329
Query: 185 TRRDRDRER-QREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKA 243
RR R +R +R+ R RDR R K R++ Y+ R RDR+++R + + ++ D +K+
Sbjct: 330 RRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKS 389
Score = 100 bits (250), Expect = 1e-21
Identities = 60/203 (29%), Positives = 99/203 (48%), Gaps = 21/203 (10%)
Query: 32 RLAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQ 91
+L R++ DRD + +E++ + ERE++R+R +E K R E++R+++
Sbjct: 233 KLRKRTEEPDRD----------ERLKKEKQEREEREKEREREREERERKRRREEEEREKE 282
Query: 92 RKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKD 151
R RDRER R R R R R R + R + +R R R+R + R R R+R D+
Sbjct: 283 RARDRER---RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRS 339
Query: 152 REIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQ-REKEDRERDRDRQKER 210
+ RDR R + R+R+ K R RDR+++R+ +EKE R D + +
Sbjct: 340 ERKHRSRSRDRRRS-------KSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVK 392
Query: 211 EKDRYRERETGRDRDKERDRERQ 233
R ++ E KE D + +
Sbjct: 393 SGSREKQSEDTNTESKESDTKNE 415
Score = 95.5 bits (236), Expect = 5e-20
Identities = 62/188 (32%), Positives = 97/188 (51%), Gaps = 19/188 (10%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
+R+ + ++E+Q + +E+ RE++RE + + R+ + +RE++R RDR+R R+R R R +
Sbjct: 242 DRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRER-RKRSRSRSRHS 300
Query: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERE 178
R RD KR + RER+R R +DR R R +ER + R R
Sbjct: 301 SRTSDRRCSRSRDHKRSRSRERRRSRS------------RDRRRSRSHDRSER-KHRSRS 347
Query: 179 RQKQRETRRDRDRERQREKE-DRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKD 237
R ++R RDR + R K DRE+DR + KE+EK R + + K RE+Q E
Sbjct: 348 RDRRRSKSRDRKSYKHRSKSRDREQDR-KSKEKEK---RGSDDKKSSVKSGSREKQSEDT 403
Query: 238 RDRQKAID 245
K D
Sbjct: 404 NTESKESD 411
Score = 80.5 bits (197), Expect = 2e-15
Identities = 50/161 (31%), Positives = 81/161 (50%), Gaps = 39/161 (24%)
Query: 102 RDRDRKRERWGDRDRETETERQEERERQRDRKREKD-RERQRQREIGIDKDREIETEKDR 160
+++ RKR DRD + E+QE ER+++R+RE++ RER+R+RE
Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRRE--------------- 275
Query: 161 DREREMGETERYRDRERERQKQRETR---------------RDRDRERQREKE-DRERDR 204
E ER ++R R+R++++ +R R RD +R R +E R R R
Sbjct: 276 -------EEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSR 328
Query: 205 DRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAID 245
DR++ R DR + R RD+ R + R R+ + R K+ D
Sbjct: 329 DRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRD 369
Score = 78.6 bits (192), Expect = 6e-15
Identities = 49/135 (36%), Positives = 70/135 (51%), Gaps = 17/135 (12%)
Query: 123 QEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRD---RERER 179
+E +E+ R R E DR+ + ++E K E EK+R+RERE E +R R+ RE+ER
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKE----KQEREEREKEREREREERERKRRREEEEREKER 283
Query: 180 QKQRETRRDRDRERQRE---------KEDRERDRDRQKEREKDRYRERETGRDRDKERDR 230
+ RE RR R R R R R+ R R +ER + R R+R R D+ +
Sbjct: 284 ARDRE-RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK 342
Query: 231 ERQREKDRDRQKAID 245
R R +DR R K+ D
Sbjct: 343 HRSRSRDRRRSKSRD 357
Score = 71.2 bits (173), Expect = 9e-13
Identities = 50/165 (30%), Positives = 73/165 (44%), Gaps = 30/165 (18%)
Query: 58 RERERQRERERQ-RKRAKERH--REKDREIEKDRD----------RQRKRDRERQRWRDR 104
RE+ER R+RER+ R R++ RH R DR + RD R R RDR R R DR
Sbjct: 279 REKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR 338
Query: 105 DRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRER 164
++ R RDR R + RDRK K R + R RE + K +++E+
Sbjct: 339 SERKHRSRSRDR--------RRSKSRDRKSYKHRSKSRDRE---------QDRKSKEKEK 381
Query: 165 EMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKE 209
+ ++ + R+KQ E +E + E D + E
Sbjct: 382 RGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
Score = 53.1 bits (126), Expect = 3e-07
Identities = 30/80 (37%), Positives = 54/80 (67%), Gaps = 3/80 (3%)
Query: 163 EREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGR 222
++ MG + E ++K R+ + DR+ + +KE +ER+ +R+KERE++R ERE R
Sbjct: 215 KQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQERE-EREKERERER-EERERKR 272
Query: 223 DRDKERDRERQREKDRDRQK 242
R++E +RE++R +DR+R+K
Sbjct: 273 RREEE-EREKERARDRERRK 291
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 100 bits (248), Expect = 2e-21
Identities = 67/172 (38%), Positives = 87/172 (50%), Gaps = 18/172 (10%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
E Q RQR+R +EK E E D + DR R+R R R+ RER DR RE
Sbjct: 2077 EYRNQTFEGRQRERFDVGPKEKPLE-EPDAQGRASEDRRRERERGRNWSRERDWDRPREW 2135
Query: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERE 178
+ R ++ R DR RE+ R R+RE K+ + E+ R+RERE RDR R+
Sbjct: 2136 DRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERE-------RDRRRD 2188
Query: 179 RQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDR 230
R + R RDRD+ R DRER RDR KDR + +E+ RD E R
Sbjct: 2189 RDRSRSRERDRDKAR-----DRERGRDR-----KDRSKSKESARDPKPEASR 2230
Score = 98.2 bits (243), Expect = 7e-21
Identities = 57/142 (40%), Positives = 82/142 (57%), Gaps = 8/142 (5%)
Query: 57 IRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
+ E + Q R+R +ER R RE + DR R+ R R++ RD DR RER +RDR
Sbjct: 2100 LEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDR 2159
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
E E +R +E +R R+R R ++RER R+R D+DR E+DRD+ R + ER RDR
Sbjct: 2160 EREADRGKEWDRSRERSRNRERERDRRR----DRDRSRSRERDRDKAR---DRERGRDR- 2211
Query: 177 RERQKQRETRRDRDRERQREKE 198
++R K +E+ RD E R +
Sbjct: 2212 KDRSKSKESARDPKPEASRASD 2233
Score = 95.1 bits (235), Expect = 6e-20
Identities = 59/140 (42%), Positives = 84/140 (60%), Gaps = 10/140 (7%)
Query: 106 RKRERWGDRDRETETERQEERER-QRDRKREKDRERQRQREIGIDKDREIETEKDRDRER 164
R+RER+ +E E + + R DR+RE++R R RE D+ RE + +D+D R
Sbjct: 2086 RQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSR 2145
Query: 165 EMGET-ERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRD 223
+ ER +R+RER+ R DR RER R +RER+RDR+++R++ R RER D
Sbjct: 2146 DWDRNRERSANRDREREADRGKEWDRSRERSR---NRERERDRRRDRDRSRSRER----D 2198
Query: 224 RDKERDRERQRE-KDRDRQK 242
RDK RDRER R+ KDR + K
Sbjct: 2199 RDKARDRERGRDRKDRSKSK 2218
Score = 52.8 bits (125), Expect = 3e-07
Identities = 34/90 (37%), Positives = 48/90 (53%), Gaps = 9/90 (10%)
Query: 36 RSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRD 95
RS DR+ RG + R R R+RER+R+R R + R RE+DR +K RDR+R RD
Sbjct: 2153 RSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDR--DKARDRERGRD 2210
Query: 96 RERQRWRDRDRKRERWGDRDRETETERQEE 125
R +DR + + RD + E R +
Sbjct: 2211 R-------KDRSKSKESARDPKPEASRASD 2233
Score = 50.4 bits (119), Expect = 2e-06
Identities = 36/93 (38%), Positives = 53/93 (56%), Gaps = 11/93 (11%)
Query: 155 ETEKDRDRER-EMGETERYRDRERERQKQRETRRDRDRERQREKE-DRERDRDRQKEREK 212
+T + R RER ++G E+ + E Q DR RER+R + RERD DR RE
Sbjct: 2081 QTFEGRQRERFDVGPKEKPLE---EPDAQGRASEDRRRERERGRNWSRERDWDRP--REW 2135
Query: 213 DRYRERETGRDRDKERDRERQREKDRDRQKAID 245
DR+R++++ RD D R R+R +RDR++ D
Sbjct: 2136 DRHRDKDSSRDWD----RNRERSANRDREREAD 2164
Score = 41.6 bits (96), Expect = 8e-04
Identities = 27/83 (32%), Positives = 48/83 (57%), Gaps = 7/83 (8%)
Query: 167 GETERYRDRERERQKQRETRRDRDRERQREKEDRE----RDRDRQKEREKDRYRERETGR 222
G+ YR++ E +QRE +E+ E+ D + DR R++ER ++ RER+ R
Sbjct: 2073 GKGHEYRNQTFEG-RQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDR 2131
Query: 223 DR--DKERDRERQREKDRDRQKA 243
R D+ RD++ R+ DR+R+++
Sbjct: 2132 PREWDRHRDKDSSRDWDRNRERS 2154
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 97.8 bits (242), Expect = 9e-21
Identities = 59/213 (27%), Positives = 126/213 (59%), Gaps = 4/213 (1%)
Query: 36 RSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRD 95
+ Q+ D D + + R I ER R+R + +R E R+ + R ++
Sbjct: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI 494
Query: 96 RERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIE 155
E+Q + R+RER +R+RE E E+++E+ER+++R+++++R++++++E+ +++++ E
Sbjct: 495 LEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQRE 554
Query: 156 TEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREK-EDRERDRDRQKEREKDR 214
EK+R +E+E E ER +++E+E QK +E ++ + E++REK E++ R+ E ++
Sbjct: 555 MEKERKQEKEK-ELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEK 613
Query: 215 YRERETGRDRDKERDRERQREKDRDRQKAIDCV 247
+E E ++++E RQ + +R ++A V
Sbjct: 614 -QESENSCNKEEEPVFTRQ-DSNRSEKEATPVV 644
Score = 90.9 bits (224), Expect = 1e-18
Identities = 57/203 (28%), Positives = 112/203 (55%), Gaps = 25/203 (12%)
Query: 54 PAIIRERERQRERERQRKRAKERHREKDREIEKDR-----DRQRKRDRERQRWRDRDRKR 108
P+ +ER K ++H DR+ R +Q+ D E + W+ R R++
Sbjct: 394 PSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVAD-EDEIWKQRRRQQ 452
Query: 109 ERWGDRDRETETERQEERERQRDRKREKDRERQRQ--REIGI-------DKDREIETEKD 159
R+EE R ++++ E+ ++ ++GI ++ RE E EK+
Sbjct: 453 SEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKE 512
Query: 160 RDREREMGETERYRDRERERQKQRETRRDRDRERQREKE-DRERDRDRQKEREKDRYRER 218
R+RE+E+ E+E++++RE R++DRERQ+EKE + E+++++Q+E EK+R +E+
Sbjct: 513 REREKEL---------EKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEK 563
Query: 219 ETGRDRDKERDRERQREKDRDRQ 241
E +R KE+++E Q+ K+++++
Sbjct: 564 EKELERQKEKEKELQKMKEQEKE 586
Score = 32.7 bits (73), Expect = 0.37
Identities = 35/145 (24%), Positives = 66/145 (45%), Gaps = 17/145 (11%)
Query: 115 DRETETERQEER----ERQRDRKR---------EKDRERQRQREIGIDK--DREIETEKD 159
D++T + QEER E Q RKR +K E++ + GI K R I++++
Sbjct: 900 DQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEP 959
Query: 160 RDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERE 219
+R E + E + R E K + + + R + R R+ +R R +
Sbjct: 960 IERPEEKPKKEGFI-RSSEGPKPEKVYKSKSETRWGPRPSSNR-REEVNDRPVRRSGPIK 1017
Query: 220 TGRDRDKERDRERQREKDRDRQKAI 244
RD + +RE+++EK+ ++ + +
Sbjct: 1018 KPVLRDMKEEREQRKEKEGEKAEKV 1042
Score = 29.3 bits (64), Expect = 4.1
Identities = 41/191 (21%), Positives = 74/191 (38%), Gaps = 22/191 (11%)
Query: 68 RQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERE 127
RQR+ ++ R D E+ R RQR + + E D+D ++ + + E
Sbjct: 1237 RQREESETRSESSDFEVVPKRRRQRGSETDTD-----SEIHESASDKDSLSKGKLPKREE 1291
Query: 128 RQRDRKREKDRER-QRQREIGIDKDREIETEKDRDRE--------------REMGETERY 172
R ++K K + + ID +R +E RD + R G T R
Sbjct: 1292 RPENKKPVKPHSSFKPDNHVRID-NRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRR 1350
Query: 173 RDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDR-E 231
R+ + R + R R + R+ + + ++ E R E+ DK + E
Sbjct: 1351 GGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPKFE 1410
Query: 232 RQREKDRDRQK 242
R+ + R+R +
Sbjct: 1411 RKFDPARERPR 1421
Score = 28.5 bits (62), Expect = 7.0
Identities = 18/78 (23%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
Query: 61 ERQRERERQRKRAKERHREKDREIEKDRDRQR--KRDRERQRWRDRDRKRERWGDRDRET 118
ER E+ ++ + K ++ K + R R +R DR R G +
Sbjct: 961 ERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPV 1020
Query: 119 ETERQEERERQRDRKREK 136
+ +EERE++++++ EK
Sbjct: 1021 LRDMKEEREQRKEKEGEK 1038
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 97.1 bits (240), Expect = 2e-20
Identities = 54/194 (27%), Positives = 95/194 (48%), Gaps = 4/194 (2%)
Query: 53 APAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRW--RDRDRKRER 110
+P R+R R R + R R++ R K R+ + R + RDR R R + RD R R
Sbjct: 406 SPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSR 465
Query: 111 WGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETE 170
++ R+ R +ER + +ER +R K+R+ + +ER+ +
Sbjct: 466 SPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRS- 524
Query: 171 RYRDRERERQKQRETRRDRDRERQRE-KEDRERDRDRQKEREKDRYRERETGRDRDKERD 229
R +ER+R++ R ++RDR + R E+RE + R +E+DR R R ++R++ +
Sbjct: 525 RSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQS 584
Query: 230 RERQREKDRDRQKA 243
R E+D R ++
Sbjct: 585 RSSSEERDHSRSRS 598
Score = 90.5 bits (223), Expect = 2e-18
Identities = 65/222 (29%), Positives = 95/222 (42%), Gaps = 24/222 (10%)
Query: 32 RLAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRA--KERHREKDREIEKDRD 89
R RS + RD R A R R + R+R R R+ K R + R K RD
Sbjct: 413 RSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARD 472
Query: 90 RQRKRDRERQR--------WRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQ 141
R R R ++R ++RD +R R ++R+ R +ER R R +ERQ
Sbjct: 473 RSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQ 532
Query: 142 RQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQRE-KEDR 200
R+ + R E+DR + R E ERE ++ R ++RDR R R ++R
Sbjct: 533 RR------QSRSPNKERDRSQSRSPSE-------EREHRQSRSPSKERDRRRWRSPSKER 579
Query: 201 ERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQK 242
ER + R E+D R R + R R +EK R +
Sbjct: 580 ERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSR 621
Score = 85.1 bits (209), Expect = 6e-17
Identities = 56/198 (28%), Positives = 83/198 (41%), Gaps = 18/198 (9%)
Query: 62 RQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETE 121
++ R + K+R + R K RDR R R + R R R R + D R
Sbjct: 385 KESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPY 444
Query: 122 RQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERER-- 179
+ +R R R + +D R R D+ R K+RD ++G + RD R R
Sbjct: 445 KARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHS-QLGSPSKERDHRRSRSP 503
Query: 180 ------------QKQRETRRDR--DRERQ-REKEDRERDRDRQKEREKDRYRERETGRDR 224
K+R+ RR R +ERQ R+ ++RDR + R RE R
Sbjct: 504 SKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSP 563
Query: 225 DKERDRERQREKDRDRQK 242
KERDR R R ++R++
Sbjct: 564 SKERDRRRWRSPSKERER 581
Score = 84.3 bits (207), Expect = 1e-16
Identities = 54/188 (28%), Positives = 80/188 (42%), Gaps = 4/188 (2%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
R ++R+ KE R + K RD R R + R R R R + DR R
Sbjct: 369 RSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRS 428
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGET-ERYRDRE 176
+ + R R + +DR R R D R K RDR R + ER +
Sbjct: 429 RSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQL 488
Query: 177 RERQKQRETRRDRD--RERQ-REKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQ 233
K+R+ RR R +ERQ R+ ++RD ++ R + R+R R +KERDR +
Sbjct: 489 GSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQS 548
Query: 234 REKDRDRQ 241
R +R+
Sbjct: 549 RSPSEERE 556
Score = 79.7 bits (195), Expect = 3e-15
Identities = 53/205 (25%), Positives = 93/205 (45%), Gaps = 8/205 (3%)
Query: 36 RSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRD 95
RS + RD R +P R+ R R + R R++ R K+R+ + ++RD
Sbjct: 441 RSPYKARD----RSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERD 496
Query: 96 RERQRWRDRDR--KRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDRE 153
R R ++R ++ R ++R+ R +ERQR + R ++ER R + ++RE
Sbjct: 497 HRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEERE 556
Query: 154 IETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRE-RDRDRQKEREK 212
+ +ER+ R +ERER++ R + +RD R R + R R +EK
Sbjct: 557 HRQSRSPSKERDR-RRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEK 615
Query: 213 DRYRERETGRDRDKERDRERQREKD 237
R R ++ + + R +E D
Sbjct: 616 AHSRSRTPSKEGNHSQSRTSSKESD 640
Score = 73.9 bits (180), Expect = 1e-13
Identities = 51/192 (26%), Positives = 77/192 (40%), Gaps = 10/192 (5%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
R R R R +KER R K+RD + ++ R + + RD
Sbjct: 345 RTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNK--QRDHS 402
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKD--REIETEKDRDREREMGETERYRDR 175
+ R+R R R K R+R R R +D R K RDR R + RD
Sbjct: 403 RSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSR-SPNKARDH 461
Query: 176 ERERQKQRETRRDRDRERQREKEDRE-----RDRDRQKEREKDRYRERETGRDRDKERDR 230
R R + R R R +E++ + ++RD ++ R + R+ R KERD
Sbjct: 462 SRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDH 521
Query: 231 ERQREKDRDRQK 242
R R ++RQ+
Sbjct: 522 RRSRSPSKERQR 533
Score = 65.1 bits (157), Expect = 7e-11
Identities = 66/257 (25%), Positives = 98/257 (38%), Gaps = 31/257 (12%)
Query: 9 PLMMDTITESFSQLLLQTRPVSWRLAMRSQIEDRDVLILRGSRVAPAIIRERERQRERER 68
P M + +S++Q ++RP S + RS R R + +R R R R
Sbjct: 259 PTEMSSRVKSYNQASTRSRPQSHSQS-RSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSR 317
Query: 69 QRK--------RAKERHREKDREIEKDRDRQRKRD----RERQRWRDRDRKRERWGDRDR 116
RK ++ R K + + R +R R R + R R +RD
Sbjct: 318 TRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDH 377
Query: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETE----KDRDREREMGETERY 172
+ ++E R + K R+ R R +DR +DR R R +
Sbjct: 378 RGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSR---SPNKA 434
Query: 173 RDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRD------- 225
RD R R + RDR R R K R+ R R + +DR R R ++RD
Sbjct: 435 RDCSRSRSPYK--ARDRSRSRSPNKA-RDHSRSRSPNKARDRSRSRSPSKERDHSQLGSP 491
Query: 226 -KERDRERQREKDRDRQ 241
KERD R R ++RQ
Sbjct: 492 SKERDHRRSRSPSKERQ 508
Score = 64.7 bits (156), Expect = 9e-11
Identities = 56/247 (22%), Positives = 93/247 (37%), Gaps = 31/247 (12%)
Query: 17 ESFSQLLLQTRPVSWR-LAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKE 75
+S+ Q+++ +R S+ M S+++ + R + + R R R ++R ++
Sbjct: 243 KSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRV 302
Query: 76 RHREKDREIEKDRDRQRK--------RDRERQRWRDRDRKRERWGDRDRETETERQEERE 127
R R + R R RK + R + + + + R R R R +E
Sbjct: 303 RSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKE 362
Query: 128 RQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRR 187
R R +ER R + + + G + RD R R + R
Sbjct: 363 RSHSHSRSSSKERDH---------RGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKA--R 411
Query: 188 DRDRERQREK-EDRERDRDRQKERE----------KDRYRERETGRDRDKERDRERQREK 236
DR R R K DR R R K R+ +DR R R + RD R R + +
Sbjct: 412 DRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKAR 471
Query: 237 DRDRQKA 243
DR R ++
Sbjct: 472 DRSRSRS 478
Score = 59.3 bits (142), Expect = 4e-09
Identities = 38/137 (27%), Positives = 61/137 (44%), Gaps = 13/137 (9%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKR----DRERQRWRD--RDRKRERW 111
R ++R+ R R +KER R + R K+RDR + R +RE ++ R ++R R RW
Sbjct: 513 RSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRW 572
Query: 112 GDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRER---EMGE 168
R ER+ + R +R+ R R ++ G + R EK R R + G
Sbjct: 573 ----RSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGN 628
Query: 169 TERYRDRERERQKQRET 185
+ R +E + T
Sbjct: 629 HSQSRTSSKESDPSQST 645
>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
sapiens]
Length = 437
Score = 95.5 bits (236), Expect = 5e-20
Identities = 57/166 (34%), Positives = 91/166 (54%), Gaps = 12/166 (7%)
Query: 85 EKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQR 144
++DRDR+R+R RER R RD++R+R R RDR + +++ ER+R R+R KD++R R+R
Sbjct: 232 DRDRDRERER-RERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKR 290
Query: 145 EIGIDKDREIETEKDRDRERE-------MGETERYRDRERERQKQRETRRDRDRERQREK 197
++R ++R+R+ E M E D + E D + +
Sbjct: 291 RSSRSRER---ARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKG 347
Query: 198 EDRERDRDRQKEREKDRYRERETGRDRDKERDR-ERQREKDRDRQK 242
DR+R+R R E++R R+R+ RDRD+E R ER E+ RD +
Sbjct: 348 RDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEAR 393
Score = 95.1 bits (235), Expect = 6e-20
Identities = 66/186 (35%), Positives = 104/186 (55%), Gaps = 18/186 (9%)
Query: 53 APAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRK---RDRERQRWRDRDRKRE 109
+P R+R+R RERER R+R++ER +E++R + RDR+R+ RD+E +R R R+R
Sbjct: 226 SPLPHRDRDRDRERER-RERSRERDKERERRRSRSRDRRRRSRSRDKEERR---RSRERS 281
Query: 110 RWGDRDRETETERQEERERQRDRKREKDR----ERQRQREIGIDKDREIETEKDRDRERE 165
+ DRDR+ + R ER R+ ++E+ R + E G D + + +
Sbjct: 282 KDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAG-DAPPDDGPPGELGPDGP 340
Query: 166 MGETERYRDRERERQK----QRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETG 221
G E+ RDR+RER++ +RE RRDRDR+R R++E + +R ER +D R G
Sbjct: 341 DGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERG--SERGRDEARGGGGG 398
Query: 222 RDRDKE 227
+D E
Sbjct: 399 QDNGLE 404
Score = 92.8 bits (229), Expect = 3e-19
Identities = 68/189 (35%), Positives = 104/189 (55%), Gaps = 28/189 (14%)
Query: 51 RVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRER 110
R P+ + R+R R+RER+R+ ER RE+D+E E+ R R R R R R R RD++ +R
Sbjct: 222 RPGPSPLPHRDRDRDRERERR---ERSRERDKERERRRSRSRDR-RRRSRSRDKEERR-- 275
Query: 111 WGDRDRETETERQEERERQRDRKREKDR-ERQRQREI---GIDKDREIET---EKDRDRE 163
R RE ++ +R+R+ R RE+ R ER+R+ E+ G D E D
Sbjct: 276 ---RSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPP 332
Query: 164 REMG----ETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERE 219
E+G + + R+R+R+++R R +R+R R R DR+RDRDR+ +R ER
Sbjct: 333 GELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDR---DRDRDRDREHKR-----GERG 384
Query: 220 TGRDRDKER 228
+ R RD+ R
Sbjct: 385 SERGRDEAR 393
Score = 77.4 bits (189), Expect = 1e-14
Identities = 53/170 (31%), Positives = 79/170 (46%), Gaps = 50/170 (29%)
Query: 119 ETERQEER-------ERQRDRKREKD-RERQRQREIGIDKDREIETEKDRD---REREMG 167
+T R +ER R RDR RE++ RER R+R DK+RE + RD R R
Sbjct: 215 DTSRYDERPGPSPLPHRDRDRDRERERRERSRER----DKERERRRSRSRDRRRRSRSRD 270
Query: 168 ETERYRDRERERQKQRETRRDRDRERQREKEDRER------------------------- 202
+ ER R RER + K R+ +R R R+R + +RER
Sbjct: 271 KEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDG 330
Query: 203 ----------DRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQK 242
D +K R++DR R R +R++ RDR+R R++DR+ ++
Sbjct: 331 PPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKR 380
Score = 64.7 bits (156), Expect = 9e-11
Identities = 38/104 (36%), Positives = 62/104 (59%), Gaps = 4/104 (3%)
Query: 140 RQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKED 199
R+ ++ I +T + +R R RDR+RER++ RE R+RD+ER+R +
Sbjct: 200 RRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERER-RERSRERDKERER-RRS 257
Query: 200 RERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKA 243
R RDR R++ R +D+ ER R+R K++DR+R+R R R++A
Sbjct: 258 RSRDR-RRRSRSRDK-EERRRSRERSKDKDRDRKRRSSRSRERA 299
Score = 62.4 bits (150), Expect = 4e-10
Identities = 66/252 (26%), Positives = 106/252 (42%), Gaps = 63/252 (25%)
Query: 52 VAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERW 111
+AP IRE E R+ + R + + EK RQ++ + E + W D
Sbjct: 41 IAP-YIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMW-DPHNDPNAQ 98
Query: 112 GDRDR----------ETETERQEERERQRDRKR------------------EKDRERQ-- 141
GD + TE++ + E E KR E + ER
Sbjct: 99 GDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMH 158
Query: 142 -------------RQREIGIDKDREIETEKDRDREREMGETER------YRDRERERQKQ 182
R+ + +++ R ++ + R +G T R R R+ +
Sbjct: 159 SAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSR 218
Query: 183 RETR--------RDRDRERQREKEDRERDRDRQKEREKDRYRE-RETGRDRDKE---RDR 230
+ R RDRDR+R+RE+ +R R+RD+++ER + R R+ R R RDKE R R
Sbjct: 219 YDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSR 278
Query: 231 ERQREKDRDRQK 242
ER ++KDRDR++
Sbjct: 279 ERSKDKDRDRKR 290
Score = 28.9 bits (63), Expect = 5.4
Identities = 23/83 (27%), Positives = 34/83 (40%), Gaps = 13/83 (15%)
Query: 41 DRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQR 100
DRD R R R+R+R R+R+R+ KR +R +R RD R
Sbjct: 349 DRDRERRRSHRSERERRRDRDRDRDRDREHKRG-------------ERGSERGRDEARGG 395
Query: 101 WRDRDRKRERWGDRDRETETERQ 123
+D E G+ R+ E +
Sbjct: 396 GGGQDNGLEGLGNDSRDMYMESE 418
>gi|213385278 TNF receptor-associated factor 3 interacting protein 1
isoform 2 [Homo sapiens]
Length = 625
Score = 94.0 bits (232), Expect = 1e-19
Identities = 56/176 (31%), Positives = 97/176 (55%), Gaps = 16/176 (9%)
Query: 64 RERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRD-RETETER 122
R +E K +E E+ R + DR +ER RDR +K E DR RE + ++
Sbjct: 145 RSQELDNKNVRE---EESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDK 201
Query: 123 QEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQ 182
++ +E +R RE +RER + R D +R+++ G ER RD ER+++ +
Sbjct: 202 EKAKENGGNRHREGERERAKAR-----------ARPDNERQKDRGNRERDRDSERKKETE 250
Query: 183 RETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDR 238
R++ +++ER R++ DRERDRD+ K+R++ R + E D D+E++RE + + +
Sbjct: 251 RKSEGGKEKERLRDR-DRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKK 305
Score = 90.1 bits (222), Expect = 2e-18
Identities = 60/182 (32%), Positives = 101/182 (55%), Gaps = 8/182 (4%)
Query: 69 QRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGD---RDRETETERQEE 125
+R A E+ K R R ++ R+ + E GD ++R T +R+++
Sbjct: 126 RRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQK 185
Query: 126 RERQRDRK-REKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR-DRERERQKQR 183
E + DRK REKD+++++ +E G ++ RE E E+ + R R E ++ R +RER+R +R
Sbjct: 186 EELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSER 245
Query: 184 ETRRDRDRERQREKEDRERDRDRQKERE--KDRYRERETGRDRDKERDRERQREKDRDRQ 241
+ +R E +EKE R RDRDR+++R+ KDR R R + + DRE+ RE D+ +
Sbjct: 246 KKETERKSEGGKEKE-RLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEK 304
Query: 242 KA 243
K+
Sbjct: 305 KS 306
Score = 87.8 bits (216), Expect = 1e-17
Identities = 61/183 (33%), Positives = 99/183 (54%), Gaps = 18/183 (9%)
Query: 36 RSQIEDRDVLILRGSRVAPAIIRERE---RQRERERQRKRAKERHREKDREIEKDRDRQR 92
+ +++ R L R + +RE E + +R KER +DR+ +++ R
Sbjct: 133 KGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR 192
Query: 93 KRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDR 152
K R++ +D+++ +E G+R RE E ER + R R D +R+KDR + ++DR
Sbjct: 193 K---PREKDKDKEKAKENGGNRHREGERERAKARARP-DNERQKDRGNR-------ERDR 241
Query: 153 EIETEKDRDREREMG-ETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKERE 211
+ E +K+ +R+ E G E ER RDR+RER R+ +DRDR R + E D DR+K RE
Sbjct: 242 DSERKKETERKSEGGKEKERLRDRDRER--DRDKGKDRDRRRVKNGE-HSWDLDREKNRE 298
Query: 212 KDR 214
D+
Sbjct: 299 HDK 301
Score = 79.7 bits (195), Expect = 3e-15
Identities = 55/166 (33%), Positives = 93/166 (56%), Gaps = 30/166 (18%)
Query: 55 AIIRERERQRERERQRKRAKERH-REKDREIEKDRD----RQRKRDRERQRWR---DRDR 106
A I+ER R+R+++ + ++R REKD++ EK ++ R R+ +RER + R D +R
Sbjct: 171 AEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNER 230
Query: 107 KRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREM 166
+++R G+R+R+ ++ER++E ER+ + +EK+R R R DR+R+R+
Sbjct: 231 QKDR-GNRERDRDSERKKETERKSEGGKEKERLRDR----------------DRERDRDK 273
Query: 167 GETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREK 212
G +DR+R R K E D DRE+ RE + E+ E K
Sbjct: 274 G-----KDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSK 314
Score = 76.6 bits (187), Expect = 2e-14
Identities = 50/180 (27%), Positives = 92/180 (51%), Gaps = 10/180 (5%)
Query: 57 IRERERQRERERQRKRAKE----RHREKDREIEKDR---DRQRKRDRERQRWRDRDRKRE 109
++E + RE+++ +++AKE RHRE +RE K R D +R++DR R+RDR E
Sbjct: 188 LKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGN---RERDRDSE 244
Query: 110 RWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGET 169
R + +R++E +++ER R RDR+R++D+ + R R + + + +++++RE + E
Sbjct: 245 RKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEK 304
Query: 170 ERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERD 229
+ E ++ T +D E + E R K ++ E D E D
Sbjct: 305 KSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGD 364
Score = 60.5 bits (145), Expect = 2e-09
Identities = 40/150 (26%), Positives = 76/150 (50%), Gaps = 12/150 (8%)
Query: 59 ERERQRER-ERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
+ ERQ++R R+R R ER +E +R+ E ++++R RDR+R+ RDRD+ ++R DR R
Sbjct: 227 DNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRE--RDRDKGKDR--DRRRV 282
Query: 118 TETERQEERERQRDRKREKDR-------ERQRQREIGIDKDREIETEKDRDREREMGETE 170
E + +R+++R+ +K E ++ G KD + ETE + T
Sbjct: 283 KNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTT 342
Query: 171 RYRDRERERQKQRETRRDRDRERQREKEDR 200
+ R + + ++ D + + +D+
Sbjct: 343 KTSKRRSKNSVEGDSTSDAEGDAGPAGQDK 372
Score = 34.3 bits (77), Expect = 0.13
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Query: 161 DREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERET 220
D R + E+ + R R D R+ E + DR K+R R+
Sbjct: 123 DAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDR 182
Query: 221 GRDRDKERDRERQREKDRDRQKA 243
+ + + DR + REKD+D++KA
Sbjct: 183 KQKEELKEDR-KPREKDKDKEKA 204
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 92.4 bits (228), Expect = 4e-19
Identities = 54/217 (24%), Positives = 126/217 (58%), Gaps = 16/217 (7%)
Query: 35 MRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKR 94
+++Q+E+ ++ + + R+ E+ +E E + + +E+ RE++ +I + ++ R++
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ 340
Query: 95 DRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKD--- 151
E W ++ R R E E++E+ RQ + EK+ + +RQ E+ +K+
Sbjct: 341 --EEMMWEKEEKMR-----RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 393
Query: 152 REIET---EKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQK 208
RE+E E+++ RE+E E + RE+E+++++E + R E+ RE+E++ R+++++
Sbjct: 394 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 453
Query: 209 EREKDRYRERETGRDRDKERDRE---RQREKDRDRQK 242
R++++ E+E R+ +K +++E RQ EK ++++
Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490
Score = 83.6 bits (205), Expect = 2e-16
Identities = 55/213 (25%), Positives = 113/213 (53%), Gaps = 14/213 (6%)
Query: 57 IRERERQRERERQRKRAKE---RHREKDREIEKDRDRQRKRDRERQRWRDRDRKRE---- 109
IRE+E + R+ ++ R +E R EK E EK + ++++++E + WR ++ RE
Sbjct: 526 IREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEK 585
Query: 110 --RWGDRDRETETERQEERE---RQRDRKREKDRERQRQREIGIDKDREI--ETEKDRDR 162
R ++ RE E +RQE+ E +Q ++ RE++ + Q Q E +++ +I + E +++
Sbjct: 586 VWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQ 645
Query: 163 EREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGR 222
E +MGE E + E+ +++E R E+ RE+E + R+++ + +++ +E+E
Sbjct: 646 EEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 705
Query: 223 DRDKERDRERQREKDRDRQKAIDCVPGRWEVTV 255
+E+ E++ + +K WE V
Sbjct: 706 WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Score = 83.2 bits (204), Expect = 2e-16
Identities = 54/196 (27%), Positives = 119/196 (60%), Gaps = 9/196 (4%)
Query: 56 IIRERERQRERERQRKRAKE---RHREKDREIE-KDRDRQRKRDRERQRWRDRD---RKR 108
I R++E+ E+E + ++ +E R EK RE E K R+++ K R+ ++ R+++ R+
Sbjct: 491 IWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREE 550
Query: 109 ERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGE 168
E+ ++++ E E+++E+E + R+ EK RE++ + +K RE E ++ E+ +
Sbjct: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
Query: 169 TERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKER 228
E+ R++E + Q+Q E R+++ E+ RE+E+ ++++ + ++++ E+E + +++E
Sbjct: 611 EEKIREQEEKIQEQEEKIREQE-EKIREQEEMTQEQEEKMGEQEEKMCEQEE-KMQEQEE 668
Query: 229 DRERQREKDRDRQKAI 244
RQ EK R+++K I
Sbjct: 669 TMWRQEEKIREQEKKI 684
Score = 81.3 bits (199), Expect = 9e-16
Identities = 53/197 (26%), Positives = 116/197 (58%), Gaps = 12/197 (6%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGD-RDRE 117
E+ R+ E + + EK +E EK R++++++++E + WR ++ RE+ R++E
Sbjct: 391 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 450
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKD-RDREREMGETERYRDRE 176
+ RQEE+ ++++ RE+++ RQ Q E+ +++ E E+ R +E+ + E+ R +E
Sbjct: 451 KKMWRQEEKIHEQEKIREEEK-RQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQE 509
Query: 177 RERQKQRETRRDRDRE--RQREKEDRERDRDRQKE---REKDRYRERETGRDRDKERDRE 231
+ +Q E R+++ + Q EK R+ ++ R++E RE+++ E+E + +K +++E
Sbjct: 510 EKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQE 569
Query: 232 ----RQREKDRDRQKAI 244
RQ EK R++++ +
Sbjct: 570 DKMWRQEEKIREQEEKV 586
Score = 80.9 bits (198), Expect = 1e-15
Identities = 54/193 (27%), Positives = 112/193 (58%), Gaps = 9/193 (4%)
Query: 58 RERERQRERERQRKRAKERHREKD---REIEKDRDRQRKRDRERQRWRDRDRKRERWGDR 114
R+ E E+E + +R +E EK+ RE+E+ Q K + ++ ++ ++ RE+ +
Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 426
Query: 115 DRETETERQEERERQRDRK-REKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173
++E + RQEE+ R+++ K RE++++ RQ E ++++ E EK +++E + E+
Sbjct: 427 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH 486
Query: 174 DRER-ERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRE- 231
++E RQK++ ++ +Q EK R+ ++ R++E EK R +E + R +K R++E
Sbjct: 487 EQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQE-EKIREQEEKMWRQEEKIREQEE 545
Query: 232 --RQREKDRDRQK 242
R+ EK +++K
Sbjct: 546 MWREEEKMHEQEK 558
Score = 80.9 bits (198), Expect = 1e-15
Identities = 57/222 (25%), Positives = 127/222 (57%), Gaps = 34/222 (15%)
Query: 57 IRERERQRERERQRK-----RAKERHREKD----REIEKDRDRQRK-RDRERQRWRDRDR 106
+ E+E+ RE+E +R+ R +E+ +E++ R+ EK R+++ K R++E++ WR ++
Sbjct: 400 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 459
Query: 107 KRERWGDRDRETETER------------QEERERQRDRKREKDRERQRQREIGIDKDREI 154
E+ R+ E E+ QEE RQ+++ E++ + ++Q E ++ +I
Sbjct: 460 IHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKI 519
Query: 155 ETEKDRDRERE---MGETERYRDRE---RERQKQRETRRDRDRERQREKEDRE-RDRDRQ 207
++++ RE+E + E+ R++E RE +K E + + E+++E+ED+ R ++
Sbjct: 520 REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKI 579
Query: 208 KEREKDRYRERETGRDRDKERDRE-----RQREKDRDRQKAI 244
+E+E+ +R+ E R+++++R + +Q EK R++++ I
Sbjct: 580 REQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
Score = 79.7 bits (195), Expect = 3e-15
Identities = 62/223 (27%), Positives = 123/223 (55%), Gaps = 38/223 (17%)
Query: 57 IRERERQRERERQRKRAKERHREKD---REIEKDRDRQRKRDRERQRWRDRDRKRER--- 110
IRE+E+++E+E + R +E+ RE++ RE EK RQ ++ E+++ R+ ++++E+
Sbjct: 419 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEM 478
Query: 111 WGDRDRETETER----------QEERERQRDRKREKDRERQRQREIGIDKDREI---ETE 157
W ++ E E QEE+ R+++ K + E+ R++E I + E + E
Sbjct: 479 WRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEE 538
Query: 158 KDRDREREMGETERYRDRER----ERQKQRETRRDRDRERQREKED---------RERDR 204
K R++E E E+ ++E+ E+++++E + R E+ RE+E+ RE++
Sbjct: 539 KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE 598
Query: 205 DRQKEREK-----DRYRERETGRDRDKERDRERQREKDRDRQK 242
RQ++ EK ++ RE+E +E+ RE Q EK R++++
Sbjct: 599 KRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE-QEEKIREQEE 640
Score = 75.9 bits (185), Expect = 4e-14
Identities = 52/205 (25%), Positives = 111/205 (54%), Gaps = 18/205 (8%)
Query: 57 IRERERQ-RERERQRKRAKERHREKDREIEKDRD----RQRKRDRERQRWRDRDRKRERW 111
IRE+E + RE+E + +R +E EK+ ++ + + ++ K R+ + +++ K R
Sbjct: 323 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 382
Query: 112 GDRDRETETERQEERERQRDRKREKDRERQRQREIGI---DKDREIETEKDRDREREMGE 168
+ E E + +E E+ ++++ +++E +RQ E I +K +E E + R E+ +
Sbjct: 383 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 442
Query: 169 TERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKE---------REKDRYRERE 219
E+ R++E++ +Q E ++++ R+ EK + + RQ+E R+K++ E+E
Sbjct: 443 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE 502
Query: 220 TGRDRDKERDRERQREKDRDRQKAI 244
+ R +E RQ EK R++++ I
Sbjct: 503 E-KIRKQEEKVWRQEEKIREQEEKI 526
Score = 75.9 bits (185), Expect = 4e-14
Identities = 48/198 (24%), Positives = 115/198 (58%), Gaps = 13/198 (6%)
Query: 57 IRERERQRERERQRKRAKERHREKD--REIEKDRDRQRK-RDRERQRWRDRDRKRERWGD 113
IRE E+++E+E ++ ++ H +++ R+ EK +++ K R +E + WR ++ RE+
Sbjct: 466 IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEK 525
Query: 114 -RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEK-----DRDRERE-- 165
R++E + RQEE+ R+++ ++ + Q +I ++ R+ + +K ++ RE+E
Sbjct: 526 IREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEK 585
Query: 166 -MGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDR 224
+ E+ R++E +RQ+Q E + + E+ RE+E++ ++++ + ++++ RE+E
Sbjct: 586 VWRQEEKIREQEEKRQEQEE-KMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQE 644
Query: 225 DKERDRERQREKDRDRQK 242
+E+ E++ + +K
Sbjct: 645 QEEKMGEQEEKMCEQEEK 662
Score = 73.2 bits (178), Expect = 2e-13
Identities = 46/197 (23%), Positives = 109/197 (55%), Gaps = 16/197 (8%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRE----RQRWRDRDRKRERWGD 113
R+ E E+E + +R +E EK+ ++ + + +++ + ++ ++++ RE+
Sbjct: 353 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 412
Query: 114 RDRETETERQEERERQRD---RKREKDRE-----RQRQREIGIDKDREIETEKDRDRERE 165
R E + QE+R+ Q R+ EK RE R++++++ +++ E EK R+ E+
Sbjct: 413 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 472
Query: 166 MGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRD 225
+ E +R E+ +++ R+ +E+ E+E++ R ++ + R++++ RE+E + R+
Sbjct: 473 QEQEEMWRQEEKIHEQEEIWRQ---KEKMHEQEEKIRKQEEKVWRQEEKIREQEE-KIRE 528
Query: 226 KERDRERQREKDRDRQK 242
+E RQ EK R++++
Sbjct: 529 QEEKMWRQEEKIREQEE 545
Score = 67.8 bits (164), Expect = 1e-11
Identities = 45/188 (23%), Positives = 102/188 (54%), Gaps = 13/188 (6%)
Query: 53 APAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWG 112
A ++ +++ Q E + K + + ++E++ R ++ ++ ++ K + W
Sbjct: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEW- 312
Query: 113 DRDRETETERQEERERQRDRK-REKDRERQRQREIGIDKDREIETEKDRDREREMGETER 171
E + + QEE+ R+++ K RE++ + +RQ E+ +K+ EK R +E M E E
Sbjct: 313 ----EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE-----EKMRRQEEMMWEKEE 363
Query: 172 YRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRE 231
R+ E ++E + R E EKE++ R+ + +K E+++ RE+E R +++E+ RE
Sbjct: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE-EKMHEQEKIREQEEKR-QEEEKIRE 421
Query: 232 RQREKDRD 239
+++ ++++
Sbjct: 422 QEKRQEQE 429
Score = 63.5 bits (153), Expect = 2e-10
Identities = 40/157 (25%), Positives = 92/157 (58%), Gaps = 5/157 (3%)
Query: 57 IRERERQR-ERERQRKRAKERHREKDREIEKDRDRQRKRDRE-RQRWRDRDRKRERWGDR 114
IRE+E +R E+E + + +E+ RE++ +I++ ++ R+++ + R++ + E+ G++
Sbjct: 593 IREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652
Query: 115 DRE--TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERY 172
+ + + E+ +E+E R+ EK RE++++ +K RE E E +++E +M E E
Sbjct: 653 EEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQE-EMMQEQEEKMWEQEEK 711
Query: 173 RDRERERQKQRETRRDRDRERQREKEDRERDRDRQKE 209
+ E+ +++E + R E+ E+E R R ++ + +
Sbjct: 712 MCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Score = 57.4 bits (137), Expect = 1e-08
Identities = 53/278 (19%), Positives = 123/278 (44%), Gaps = 77/278 (27%)
Query: 40 EDRDVLILRGSR--VAPAIIRERERQRERERQRKRAKERHREKD-REIEKDRDRQR---- 92
++RD L L R + ++E+ + + + Q +++ + + +E+++ +R +
Sbjct: 200 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP 259
Query: 93 -----------------------------------KRDRERQRWRDRDRKRERWGDRDRE 117
+ +E + WR ++ K + W ++ +E
Sbjct: 260 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR-QEEKIQEWEEKIQE 318
Query: 118 TET------------------------ERQEERERQRDRKREKDRERQRQREIGIDKDRE 153
E E++E+ RQ + EK+ + +RQ E+ +K+ +
Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 378
Query: 154 I---------ETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDR 204
+ + EK R+ E +M E E+ R++E +RQ++ + R R+ Q K R+ ++
Sbjct: 379 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 438
Query: 205 DRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQK 242
R++E EK R +E++ R +K ++E+ RE+++ +++
Sbjct: 439 IREQE-EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQ 475
Score = 35.0 bits (79), Expect = 0.075
Identities = 36/210 (17%), Positives = 96/210 (45%), Gaps = 16/210 (7%)
Query: 33 LAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQR 92
+A + + DR + L R A ++ R + E + K AK + + + E EK +
Sbjct: 184 VATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLN 243
Query: 93 KRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDR 152
++ +R+ +R + ++Q + E K + + Q ++ ++
Sbjct: 244 VKELKRKL------------ERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV---EEN 288
Query: 153 EIETEKDRDREREMG-ETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKERE 211
E+ ++ +E +M + E+ ++ E + Q+Q E R+++ + + ++E R + E+E
Sbjct: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 348
Query: 212 KDRYRERETGRDRDKERDRERQREKDRDRQ 241
+ R+ E +++++ R+ + +++ +
Sbjct: 349 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 378
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 92.4 bits (228), Expect = 4e-19
Identities = 58/202 (28%), Positives = 101/202 (50%), Gaps = 20/202 (9%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRD-- 115
+ + ++R + + R ++KE+ + K+R+ + +R+ + KR R R + RD + +E+ D
Sbjct: 449 KNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEE-KRMRSRSKGRDHENVKEKEKQSDSK 507
Query: 116 -RETETERQEERERQRDRK---------REKDRERQ-RQREIGIDKDREIETEKDRDRER 164
++ E R +E+ +Q + K +EKDR Q R RE I K + + R+R R
Sbjct: 508 GKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSR 567
Query: 165 EMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQ----KEREKDRYRERET 220
+ R R R +R + R R RE++ + R R R+R+ + R KDR R R
Sbjct: 568 SRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRD 627
Query: 221 GRDRDKERDRERQREKDRDRQK 242
R ER+ + R KD+ R +
Sbjct: 628 SRS--SEREESQSRNKDKYRNQ 647
Score = 88.6 bits (218), Expect = 6e-18
Identities = 67/219 (30%), Positives = 106/219 (48%), Gaps = 39/219 (17%)
Query: 58 RERERQRERERQ-------RKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRER 110
+ER+ +R E+ +KRAK + R K +E K ++R K +R ++ R R R +
Sbjct: 434 KERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEK---RMRSRSK 490
Query: 111 WGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDK-DREIETEKDR---DREREM 166
D + E E+Q + + +D++R + +E+ +Q E ++ D EKDR R RE
Sbjct: 491 GRDHENVKEKEKQSD-SKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSREC 549
Query: 167 GETE-------RYRDRERERQKQRETR---RDRDRERQ------REKEDRERDRDRQKE- 209
T+ R R+R R R + R R DRDR R RE+E R R R R +E
Sbjct: 550 DITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRER 609
Query: 210 -------REKDRYRERETGRDRDKERDRERQREKDRDRQ 241
R KDR R R R ++E + R ++K R+++
Sbjct: 610 RTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQE 648
Score = 85.9 bits (211), Expect = 4e-17
Identities = 55/195 (28%), Positives = 96/195 (49%), Gaps = 14/195 (7%)
Query: 57 IRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQ-----RWRDRDRKRERW 111
+R +ER+ R + R EK+++++ + ++RD R +++++ +KR +
Sbjct: 399 VRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKS 458
Query: 112 GDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETER 171
R + E + +ER+ + +R EK R R R G D + E EK D + + + ER
Sbjct: 459 KSRSKSKEKSKSKERDSKHNRNEEK---RMRSRSKGRDHENVKEKEKQSDSKGK--DQER 513
Query: 172 YRDRERERQ---KQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKER 228
R +E+ +Q K E + +E+ R + R R+ D K + R RE R RD+ R
Sbjct: 514 SRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSR 573
Query: 229 DRERQREKDRDRQKA 243
R R R DRDR ++
Sbjct: 574 -RVRSRTHDRDRSRS 587
Score = 85.9 bits (211), Expect = 4e-17
Identities = 59/212 (27%), Positives = 105/212 (49%), Gaps = 37/212 (17%)
Query: 62 RQRERERQRKRAKERHREKD--REIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETE 119
R+ E+E++ K K +E+D R EKD D+ + + ++R + + R + +E+ ++R+++
Sbjct: 418 RKNEKEKKVKDHKSNSKERDIRRNSEKD-DKYKNKVKKRAKSKSRSKSKEKSKSKERDSK 476
Query: 120 TERQEERERQRDRKREKDRERQRQREI-----GIDKDREIETEKDRDREREMGETERYRD 174
R EE+ R R R + +D E +++E G D++R EK + E + E + +
Sbjct: 477 HNRNEEK-RMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKS 535
Query: 175 RERERQKQRETR---------------------RDRDRERQREKEDRERDRDRQKEREKD 213
+E++R+ Q +R RD R R R DRDR + +E
Sbjct: 536 KEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRD----RSRRVRSRTHDRDRSRSKEYH 591
Query: 214 RYRERE---TGRDRDKERDRERQREKDRDRQK 242
RYRE+E GR R +ER R + +DR++
Sbjct: 592 RYREQEYRRRGRSRSRERRTPPGRSRSKDRRR 623
Score = 84.7 bits (208), Expect = 8e-17
Identities = 58/197 (29%), Positives = 94/197 (47%), Gaps = 17/197 (8%)
Query: 61 ERQRERERQRKRAKERHREKDREIE-KDRDRQRKRDRERQRW-------RDRDRKRE--- 109
E +R R R + R E +EK+++ + K +D++R R +E+ + D + +E
Sbjct: 481 EEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDR 540
Query: 110 RWGDRDRETETERQEERERQRDRKREKDRERQRQ-REIGIDKDREIETEKDRDREREMGE 168
R R RE + + + R R+R + R+R R+ R D+DR E R RE+E
Sbjct: 541 RAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRR 600
Query: 169 TERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKER 228
R R RER R +DR R+R ++ R +R+ + R KD+YR +E+ KE
Sbjct: 601 RGRSRSRERRTPPGRSRSKDR---RRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKEN 657
Query: 229 DRERQR--EKDRDRQKA 243
+R K RD +
Sbjct: 658 SESEKRMYSKSRDHNSS 674
Score = 77.4 bits (189), Expect = 1e-14
Identities = 56/229 (24%), Positives = 112/229 (48%), Gaps = 24/229 (10%)
Query: 28 PVSWRLAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKD 87
P WR M+ R + G R E +E +R R KER R + +
Sbjct: 359 PPHWRQEMQRAQRMR---VSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSES 415
Query: 88 RDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIG 147
+R+ +++++ + + ++R D R +E ++++ + + +KR K + R + +E
Sbjct: 416 PNRKNEKEKKVKDHKSNSKER----DIRRNSE---KDDKYKNKVKKRAKSKSRSKSKEKS 468
Query: 148 IDKDREIETEKDRDREREMGETERYRDRE--RERQKQRETR-RDRDRERQREK----EDR 200
K+R+ ++ +R+ E+ M + RD E +E++KQ +++ +D++R R +EK E +
Sbjct: 469 KSKERD--SKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESK 526
Query: 201 ERDRDRQKEREKDRY-----RERETGRDRDKERDRERQREKDRDRQKAI 244
+ D K +EKDR RE + + + R R+R + RDR + +
Sbjct: 527 SNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRV 575
Score = 77.0 bits (188), Expect = 2e-14
Identities = 58/219 (26%), Positives = 98/219 (44%), Gaps = 25/219 (11%)
Query: 36 RSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRD 95
R+Q R+ I +G + R RER R R+R R+ H DR R R
Sbjct: 541 RAQSRSRECDITKGKHSYNS--RTRERSRSRDRSRRVRSRTH-----------DRDRSRS 587
Query: 96 RERQRWRDRD-RKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREI 154
+E R+R+++ R+R R R+R T R ++R+R R+ + ER+ + DK R
Sbjct: 588 KEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQ 647
Query: 155 ETEKDRDREREMGETERY---RDRERERQKQRETRRDRDR----ERQREKEDRERDRDRQ 207
E++ +E E Y RD RE + DRD+ + ++ +D E
Sbjct: 648 ESKSSHRKENSESEKRMYSKSRD-HNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSML 706
Query: 208 KEREKDRYR---ERETGRDRDKERDRERQREKDRDRQKA 243
K +E ++ R E+E + + +E D ++ K D + +
Sbjct: 707 KNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESS 745
Score = 68.9 bits (167), Expect = 5e-12
Identities = 64/259 (24%), Positives = 109/259 (42%), Gaps = 69/259 (26%)
Query: 58 RERERQRERE------------------RQRKRAKERHREKDREIEKDRDRQRKRDRE-- 97
+ RER+RERE R ++ K R + R + R R R R E
Sbjct: 300 KNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETP 359
Query: 98 ---RQRWRDRDRKR----ERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDK 150
RQ + R R ERW D+ +E E +E QR R K+R+ R +
Sbjct: 360 PHWRQEMQRAQRMRVSSGERWIKGDK---SELNEIKENQRSPVRVKERKITDHRNVSESP 416
Query: 151 DREIETEK----------DRDREREMGETERYRDR--------------ERERQKQRETR 186
+R+ E EK +RD R + ++Y+++ E+ + K+R+++
Sbjct: 417 NRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSK 476
Query: 187 RDRDRERQREKEDRERDRDRQKEREK---DRYRERETGRDRDK---------ERDRERQR 234
+R+ E++ + RD + KE+EK + +++E R ++K E D + +
Sbjct: 477 HNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSK 536
Query: 235 EKDR---DRQKAIDCVPGR 250
EKDR R + D G+
Sbjct: 537 EKDRRAQSRSRECDITKGK 555
Score = 67.8 bits (164), Expect = 1e-11
Identities = 51/240 (21%), Positives = 106/240 (44%), Gaps = 57/240 (23%)
Query: 56 IIRERERQRERERQRKRAKERHREKD----------------REIEKDRDRQRKRDRERQ 99
++R+ + + + ++ R +ER RE + R K + R +R R
Sbjct: 286 LMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPS 345
Query: 100 RWRDRDRKR-----------------------ERWGDRDRETETERQEERERQRDRKREK 136
R R RDR R ERW D+ +E E +E QR R K
Sbjct: 346 RSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDK---SELNEIKENQRSPVRVK 402
Query: 137 DRERQRQREIGIDKDREIETE----------KDRDREREMGETERYRDRERERQKQRETR 186
+R+ R + +R+ E E K+RD R + ++Y+++ ++R K +
Sbjct: 403 ERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRS 462
Query: 187 RDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKE-----RDRERQREKDRDRQ 241
+ +++ + +E++ + + ++ R + + R+ E ++++K+ +D+ER R K++ +Q
Sbjct: 463 KSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQ 522
Score = 62.8 bits (151), Expect = 3e-10
Identities = 46/186 (24%), Positives = 82/186 (44%), Gaps = 18/186 (9%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
R+R R +E R R++ R + R R R+R R R +DR+R R R
Sbjct: 582 RDRSRSKEYHRYREQEYRR---------RGRSRSRERRTPPGRSRSKDRRRRRRDSR--- 629
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRER 177
+ER+E + R +D+ R ++ + ++E + R K RD E+ DR++
Sbjct: 630 -SSEREESQSRNKDKYRNQESKSSHRKENSESEKRMY--SKSRDHNSSNNSREKKADRDQ 686
Query: 178 ---ERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQR 234
+ KQ + + KED + +KE +K + +E + +++K+ D E
Sbjct: 687 SPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSP 746
Query: 235 EKDRDR 240
D D+
Sbjct: 747 GTDEDK 752
Score = 38.1 bits (87), Expect = 0.009
Identities = 35/205 (17%), Positives = 74/205 (36%), Gaps = 13/205 (6%)
Query: 49 GSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKR 108
G + + +++ E++R + + + + + D ++ + R +K
Sbjct: 175 GELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKH 234
Query: 109 ERWGDRDRETETERQEERERQRDRKREKDRERQ-----RQREIGIDKDREIETEKDRDRE 163
+ + ++ + +R++ ++ ++ E Q R EI + K +
Sbjct: 235 RKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKA 294
Query: 164 REMGETERYRDRERERQKQRETRRDRDRE-------RQREKEDRERDRDRQKEREKDRYR 216
E R R+RERE R R+ + R R + R +DR+R
Sbjct: 295 DEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFR 354
Query: 217 ERETGRDRDKERDR-ERQREKDRDR 240
ET +E R +R R +R
Sbjct: 355 RSETPPHWRQEMQRAQRMRVSSGER 379
Score = 37.7 bits (86), Expect = 0.012
Identities = 36/193 (18%), Positives = 76/193 (39%), Gaps = 22/193 (11%)
Query: 66 RERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEE 125
+ + +K K+RH+ D D + D E+ TE + +
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSS-----------DSSDSESATEEKSK 228
Query: 126 RERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRD----RERERQK 181
+ +++ RK + ++++++ K E+E + + E + T R + E
Sbjct: 229 KRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAE-NLEAQPQSTVRPEEIPPIPENRFLM 287
Query: 182 QRETRRDRDRERQREKEDRERD---RDRQKEREKDRYRERETGR---DRDKERDRERQRE 235
++ + ++ER+ + +RER+ + Q + R +GR R R R R
Sbjct: 288 RKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRS 347
Query: 236 KDRDRQKAIDCVP 248
+ RDR + + P
Sbjct: 348 RSRDRFRRSETPP 360
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 91.7 bits (226), Expect = 7e-19
Identities = 60/195 (30%), Positives = 104/195 (53%), Gaps = 12/195 (6%)
Query: 58 RERERQRERERQRKRAKERHREKDRE-IEKDRDRQRKRDRERQRWRDRDRKRER---WGD 113
R R+R R RER R R K R R +DR+ + + R R+R R RER+R R RDR+R R G
Sbjct: 41 RSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGR 100
Query: 114 RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173
R R + + ++ R R +EK + +E DKD +K+ ++E++ G + +
Sbjct: 101 RSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKD-----DKEDEKEKDAGNFD--Q 153
Query: 174 DRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQ 233
++ E ++R+ R ++ RE QR+K E + +KE E+ + ++ + D D + D +
Sbjct: 154 NKLEEEMRKRKERVEKWREEQRKKA-MENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAE 212
Query: 234 REKDRDRQKAIDCVP 248
EK+ + + + P
Sbjct: 213 AEKEGNEMEGEELDP 227
Score = 87.0 bits (214), Expect = 2e-17
Identities = 55/182 (30%), Positives = 97/182 (53%), Gaps = 4/182 (2%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
R R R R KR+K + R ++DR R+R R R+++R R RDRKR R R RE
Sbjct: 17 RSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLR-RSRSRE 75
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETE-KDRDRER-EMGETERYRDR 175
+ R+ R R RDR+R + R R R+ ++ +TE + R +E+ + GE+ + + +
Sbjct: 76 RDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKK 135
Query: 176 ER-ERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQR 234
++ +++ ++E + + E+E R+R +K RE+ R + E + KE + +Q
Sbjct: 136 DKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQG 195
Query: 235 EK 236
+K
Sbjct: 196 KK 197
Score = 85.1 bits (209), Expect = 6e-17
Identities = 54/176 (30%), Positives = 88/176 (50%), Gaps = 4/176 (2%)
Query: 64 RERERQRKRAKERHREKDREIEKD-RDRQRKR-DRERQRWRDRDRKRERWGDRDRETETE 121
RE RKR+ R R R + D++ KR D R R RDRDR+RER RD+
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62
Query: 122 RQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQK 181
R +R R R R RE+DR R+R+R D+ R + R + + R R K
Sbjct: 63 RDRKRLR-RSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSK 121
Query: 182 QRETRRDRDRERQREKEDRERDRDRQKER-EKDRYRERETGRDRDKERDRERQREK 236
++ + +E++++K+D+E ++++ ++++ E R E+ RE QR+K
Sbjct: 122 EKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKK 177
Score = 82.4 bits (202), Expect = 4e-16
Identities = 47/147 (31%), Positives = 71/147 (48%), Gaps = 7/147 (4%)
Query: 96 RERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIE 155
RE + +R R R R G R R ++R ++ D +R + R+R R+RE +D+
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPS--DKRSKRGDDRRSRSRDRDRRRERSRSRDKRRS 60
Query: 156 TEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRY 215
+DR R R ER R RER R + R+ RR R R R R +K + R
Sbjct: 61 RSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRS 120
Query: 216 RERETGRDRDKER-----DRERQREKD 237
+E+ G + KE+ D+E ++EKD
Sbjct: 121 KEKTDGGESSKEKKKDKDDKEDEKEKD 147
Score = 61.6 bits (148), Expect = 8e-10
Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Query: 152 REIETEKDRDRER-EMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKER 210
RE + R R G R R +R K+ + RR R R+R R +E R R RD+++ R
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRE-RSRSRDKRRSR 61
Query: 211 EKDRYR-ERETGRDRDKERDRERQREKDRDRQKA 243
+DR R R R+RD+ R+R R R +DR R ++
Sbjct: 62 SRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRS 95
Score = 55.5 bits (132), Expect = 5e-08
Identities = 33/92 (35%), Positives = 51/92 (55%), Gaps = 7/92 (7%)
Query: 160 RDREREMGETERYRDRERERQKQRETR-RDRDRERQREKEDRERDRDRQKEREKDRYRER 218
R R + D+ +R R +R RDRDR R +R R RD+++ R +DR R R
Sbjct: 15 RGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRR-----ERSRSRDKRRSRSRDRKRLR 69
Query: 219 ETGRDRDKERDRERQREKDRDRQKAIDCVPGR 250
+ R R+++R RER+R + RDR+++ GR
Sbjct: 70 RS-RSRERDRSRERRRSRSRDRRRSRSRSRGR 100
Score = 36.6 bits (83), Expect = 0.026
Identities = 32/145 (22%), Positives = 61/145 (42%), Gaps = 28/145 (19%)
Query: 58 RERERQRERERQRKRAKERHREKDR---EIEKDRD-----------RQRKRDRERQRWRD 103
+ R R +E+ + ++KD+ E EK++D RKR ++WR+
Sbjct: 113 KTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWRE 172
Query: 104 RDRKR--ERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRD 161
RK+ E G+ +E E +Q ++ D ++D + ++E E+E E
Sbjct: 173 EQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKE-----GNEMEGE---- 223
Query: 162 REREMGETERYRDRERERQKQRETR 186
E+ + Y + +E K+ R
Sbjct: 224 ---ELDPLDAYMEEVKEEVKKFNMR 245
>gi|20070262 TNF receptor-associated factor 3 interacting protein 1
isoform 1 [Homo sapiens]
Length = 691
Score = 90.1 bits (222), Expect = 2e-18
Identities = 60/182 (32%), Positives = 101/182 (55%), Gaps = 8/182 (4%)
Query: 69 QRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGD---RDRETETERQEE 125
+R A E+ K R R ++ R+ + E GD ++R T +R+++
Sbjct: 126 RRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQK 185
Query: 126 RERQRDRK-REKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR-DRERERQKQR 183
E + DRK REKD+++++ +E G ++ RE E E+ + R R E ++ R +RER+R +R
Sbjct: 186 EELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSER 245
Query: 184 ETRRDRDRERQREKEDRERDRDRQKERE--KDRYRERETGRDRDKERDRERQREKDRDRQ 241
+ +R E +EKE R RDRDR+++R+ KDR R R + + DRE+ RE D+ +
Sbjct: 246 KKETERKSEGGKEKE-RLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEK 304
Query: 242 KA 243
K+
Sbjct: 305 KS 306
Score = 89.7 bits (221), Expect = 3e-18
Identities = 52/175 (29%), Positives = 95/175 (54%), Gaps = 14/175 (8%)
Query: 64 RERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQ 123
R +E K +E E+ R + DR +ER RDR +K E DR + E ++
Sbjct: 145 RSQELDNKNVRE---EESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR-KPREKDKD 200
Query: 124 EERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQR 183
+E+ ++ R ++ ER+R + D +R+++ G ER RD ER+++ +R
Sbjct: 201 KEKAKENGGNRHREGERERAK---------ARARPDNERQKDRGNRERDRDSERKKETER 251
Query: 184 ETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDR 238
++ +++ER R++ DRERDRD+ K+R++ R + E D D+E++RE + + +
Sbjct: 252 KSEGGKEKERLRDR-DRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKK 305
Score = 87.8 bits (216), Expect = 1e-17
Identities = 61/183 (33%), Positives = 99/183 (54%), Gaps = 18/183 (9%)
Query: 36 RSQIEDRDVLILRGSRVAPAIIRERE---RQRERERQRKRAKERHREKDREIEKDRDRQR 92
+ +++ R L R + +RE E + +R KER +DR+ +++ R
Sbjct: 133 KGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR 192
Query: 93 KRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDR 152
K R++ +D+++ +E G+R RE E ER + R R D +R+KDR + ++DR
Sbjct: 193 K---PREKDKDKEKAKENGGNRHREGERERAKARARP-DNERQKDRGNR-------ERDR 241
Query: 153 EIETEKDRDREREMG-ETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKERE 211
+ E +K+ +R+ E G E ER RDR+RER R+ +DRDR R + E D DR+K RE
Sbjct: 242 DSERKKETERKSEGGKEKERLRDRDRER--DRDKGKDRDRRRVKNGE-HSWDLDREKNRE 298
Query: 212 KDR 214
D+
Sbjct: 299 HDK 301
Score = 81.6 bits (200), Expect = 7e-16
Identities = 58/206 (28%), Positives = 112/206 (54%), Gaps = 20/206 (9%)
Query: 55 AIIRERERQRERERQRKRAKERH-REKDREIEKDRD----RQRKRDRERQRWR---DRDR 106
A I+ER R+R+++ + ++R REKD++ EK ++ R R+ +RER + R D +R
Sbjct: 171 AEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNER 230
Query: 107 KRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRER-E 165
+++R G+R+R+ ++ER++E ER+ + +EK+R R R D++R+ + KDRDR R +
Sbjct: 231 QKDR-GNRERDRDSERKKETERKSEGGKEKERLRDR------DRERDRDKGKDRDRRRVK 283
Query: 166 MGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKD----RYRERETG 221
GE DRE+ R+ + ++ +K +D + E E + + T
Sbjct: 284 NGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTK 343
Query: 222 RDRDKERDRERQREKDRDRQKAIDCV 247
+ + ++ R++D K++D +
Sbjct: 344 TSKRRSKNSVEGRKEDNISAKSLDSI 369
Score = 34.3 bits (77), Expect = 0.13
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Query: 161 DREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERET 220
D R + E+ + R R D R+ E + DR K+R R+
Sbjct: 123 DAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDR 182
Query: 221 GRDRDKERDRERQREKDRDRQKA 243
+ + + DR + REKD+D++KA
Sbjct: 183 KQKEELKEDR-KPREKDKDKEKA 204
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 90.1 bits (222), Expect = 2e-18
Identities = 76/207 (36%), Positives = 113/207 (54%), Gaps = 33/207 (15%)
Query: 48 RGSRVAPAIIRERERQRERER--QRKRAKERHREKDREIEKDRDRQRKRDRERQRWRD-R 104
RG R A ++++ ++E+E + KR E +RE D++ + RD + RD R
Sbjct: 303 RGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREF--DKENEVFRDWNSRIPRDVR 360
Query: 105 DRKRERWGDRDRETETER-----QEERERQRDRKRE-----KDRERQRQREIGIDKDREI 154
D E + D + E ER Q E R + + E ++RER+R+RE ++ RE
Sbjct: 361 DTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERE---NRQRER 417
Query: 155 ETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDR 214
E E++RDRERE R RERER+++ E RD+ERQR KE+ ER+R K EKDR
Sbjct: 418 ERERERDRERER------RQREREREREHE----RDKERQRRKEEWERER--AKRDEKDR 465
Query: 215 YRERETGRDRDKERDRERQREKDRDRQ 241
+ RDR+KER++E+ + K R Q
Sbjct: 466 ---QHRDRDREKEREKEKGKPKPRSPQ 489
Score = 76.6 bits (187), Expect = 2e-14
Identities = 69/226 (30%), Positives = 109/226 (48%), Gaps = 36/226 (15%)
Query: 56 IIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRE------------------ 97
I +E+E E +R E RE D+E E RD + R+
Sbjct: 317 IRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYEI 376
Query: 98 RQRWRDRDRKRERWGDRDRET-----ETERQEERE-RQRDRKREKDRERQRQREIGIDKD 151
+ WR + R + E E ER+ ERE RQR+R+RE++R+R+R+R ++
Sbjct: 377 ERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERR---QRE 433
Query: 152 REIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKE-DRERDRDRQ--- 207
RE E E +RD+ER+ + E R+R + +K R+ RDRDRE++REKE + + R Q
Sbjct: 434 REREREHERDKERQRRKEEWERERAKRDEKDRQ-HRDRDREKEREKEKGKPKPRSPQPPS 492
Query: 208 KEREKDRYRERETG---RDRDKERDRERQREKDRDRQKAIDCVPGR 250
++ E + TG + D+ +D R R K ++ + P R
Sbjct: 493 RQAEPPKKEAATTGPQVKRADEWKDPWR-RSKSPKKKLGVSVSPSR 537
Score = 29.6 bits (65), Expect = 3.2
Identities = 37/145 (25%), Positives = 61/145 (42%), Gaps = 8/145 (5%)
Query: 36 RSQIEDRDVLIL-RGSRVAPAIIRERERQRERERQ-RKRAKERHREKDREIEKDRDRQRK 93
+SQ +D +V L RG +P E + +R R A RE D E E D D +
Sbjct: 77 KSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELD-EHELDYDEEVP 135
Query: 94 RDRERQRWRDRDRKRERWGDRDRETETERQEERERQRD--RKREKDRERQRQREIGIDKD 151
+ D K D ++ T R+E + + K + +++++E D D
Sbjct: 136 EEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKE---DDD 192
Query: 152 REIETEKDRDREREMGETERYRDRE 176
EI+ + D + E GE + DR+
Sbjct: 193 GEIDDGEIDDDDLEEGEVKDPSDRK 217
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 89.0 bits (219), Expect = 4e-18
Identities = 55/182 (30%), Positives = 95/182 (52%), Gaps = 9/182 (4%)
Query: 61 ERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET-- 118
ER+ +RE++R R + E D++ E++RDR+R DRE + R RD R G + +
Sbjct: 1200 EREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSW 1259
Query: 119 -ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRER 177
++ R+++R+R DR+RE+D R + + DR+ R E+ R DR+
Sbjct: 1260 RDSSRRDDRDRD-DRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKD 1318
Query: 178 ERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKD 237
+R ++R+ R +R+RDR+R+ E+EK +R ++D+E R + E D
Sbjct: 1319 DRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWR-----AEKDRESLRRTKNETD 1373
Query: 238 RD 239
D
Sbjct: 1374 ED 1375
Score = 87.8 bits (216), Expect = 1e-17
Identities = 61/191 (31%), Positives = 98/191 (51%), Gaps = 22/191 (11%)
Query: 64 RERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQ 123
RE+E+ R+ + RE E++ DR+++RDR+ Q + D+ ER +RDRE + +R+
Sbjct: 1179 REKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPER--ERDRERDVDRE 1236
Query: 124 EERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQR 183
+ R RD E R E +D ++DRD R R RD R+ +++R
Sbjct: 1237 DRFRRPRD---EGGWRRGPAEESSSWRDSSRRDDRDRDDRR------RERDDRRDLRERR 1287
Query: 184 ETRRDRDRERQREKEDRERDRD--RQKEREKDRYRERET---------GRDRDKERDRER 232
+ R DRDR + +RE R +R+ DR ER+ RDR+++RDRER
Sbjct: 1288 DLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDRER 1347
Query: 233 QREKDRDRQKA 243
+ EK++ +A
Sbjct: 1348 EGEKEKASWRA 1358
Score = 84.7 bits (208), Expect = 8e-17
Identities = 70/227 (30%), Positives = 107/227 (47%), Gaps = 27/227 (11%)
Query: 35 MRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKR 94
M +EDRD+ ++R ++ E+ +Q E + A+ERH + +R RQRK
Sbjct: 750 MSRMLEDRDLFVMRLKAARQSVYEEKLKQFEE----RLAEERHNRLE-----ERKRQRKE 800
Query: 95 DRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREI 154
+R +R+++ + +R R E + +EERER KRE++ ++R + K E+
Sbjct: 801 ERRITYYREKEEEEQR---RAEEQMLKEREERERAERAKREEELREYQER---VKKLEEV 854
Query: 155 ETEKDRDREREMGETERYRDRERERQKQRETRR-----DRDRERQREKEDRERDRDRQKE 209
E +K R RE E+ E ER R+ ER +R+ DRD E K R+
Sbjct: 855 ERKK-RQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGP 913
Query: 210 REKDRYRERETGRDRDKERDRERQRE--KDRDRQKAI----DCVPGR 250
EK+ R DR RD ER R D DR+ ++ D VP R
Sbjct: 914 PEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRR 960
Score = 83.2 bits (204), Expect = 2e-16
Identities = 66/233 (28%), Positives = 104/233 (44%), Gaps = 54/233 (23%)
Query: 62 RQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQR------------------WRD 103
R + +R +R E R R ++ DR +R D R WR+
Sbjct: 1121 RNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWRE 1180
Query: 104 RDRKRER-WG-DRDRETETERQEERERQRDR------KREKDRERQRQREIGIDKDREIE 155
+++ RE WG R+ ER+ +RE++RDR + +KD ER+R RE +D++
Sbjct: 1181 KEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFR 1240
Query: 156 TEKDRD--REREMGETERYRDRERERQKQRETRRDR--DRERQREKEDRERDRDRQ---- 207
+D R E+ +RD R + R+ RR DR RE+ D DRDR+
Sbjct: 1241 RPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPL 1300
Query: 208 -------------KEREKDRYRERETGR-------DRDKERDRERQREKDRDR 240
+R+ DR ER+ R RD+ERDR+R+RE ++++
Sbjct: 1301 RSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEK 1353
Score = 79.0 bits (193), Expect = 5e-15
Identities = 78/272 (28%), Positives = 117/272 (43%), Gaps = 50/272 (18%)
Query: 17 ESFSQLLLQTRPVSWRLAMRSQIEDRDVLILRGS------RVAPAIIRERERQRERERQR 70
+ F + L + R R + E+R + R R +++ERE +RER +
Sbjct: 777 KQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKERE-ERERAERA 835
Query: 71 KRAKE--RHREKDREIEKDRDRQRKRD-----RERQRWRDR-------DRKRERWGDRD- 115
KR +E ++E+ +++E+ ++R+R+ RER+R +R RK RWGDRD
Sbjct: 836 KREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDS 895
Query: 116 --------------RETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRD 161
R E++ R RD R R+ +R R +G D+DRE D D
Sbjct: 896 EGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDD 955
Query: 162 REREMGETERYRDRERERQKQRETRR--DRDRERQREKED-----RERDRDRQKEREKDR 214
R G + R R ++ R +RR D DR R +D R D DR R D
Sbjct: 956 RVPRRGMDDD-RGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADD 1014
Query: 215 YRERETGRDRDK------ERDRERQREKDRDR 240
R G D D+ + DR +R D DR
Sbjct: 1015 DRPPRRGLDEDRGSWRTADEDRGPRRGMDDDR 1046
Score = 70.5 bits (171), Expect = 2e-12
Identities = 66/226 (29%), Positives = 101/226 (44%), Gaps = 32/226 (14%)
Query: 48 RGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWR--DRD 105
RG R R R + +R +R + R R ++ DR +R D +R WR D D
Sbjct: 1067 RGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDD 1126
Query: 106 RKRERWGDRDRETETERQEERERQR---DR--KREKD---------------RERQRQRE 145
R R + DR ++R +R DR +R D RE+++ RE
Sbjct: 1127 RIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKARE 1186
Query: 146 IGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDR-ERDR 204
RE ++R+ +RE ER RD + + ++ R+RDRER ++EDR R R
Sbjct: 1187 ESWGPPRESRPSEEREWDREK---ERDRDNQDREENDKDPERERDRERDVDREDRFRRPR 1243
Query: 205 D-----RQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAID 245
D R E +R+ DRD++ DR R+R+ RD ++ D
Sbjct: 1244 DEGGWRRGPAEESSSWRDSSRRDDRDRD-DRRRERDDRRDLRERRD 1288
Score = 57.0 bits (136), Expect = 2e-08
Identities = 47/187 (25%), Positives = 88/187 (47%), Gaps = 17/187 (9%)
Query: 67 ERQRKRAKERHREKDREIEKDRDRQR-------KRDRERQRWRDRDRKRERWGDRDRETE 119
E+++K +ER + ++++I+ +R K E QR +D D W ++ E
Sbjct: 678 EKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDL----WEQQEEERI 733
Query: 120 TERQEERERQRDRKREKDRERQRQREIGIDK----DREIETEKDRDREREMGETERYRDR 175
T Q ERE+ + K R + R++ + + + + EK + E + E R
Sbjct: 734 TTMQLEREKALEHKNRMSRMLE-DRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLE 792
Query: 176 ERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQRE 235
ER+RQ++ E R RE++ E+E R + KERE+ ER + +E ++
Sbjct: 793 ERKRQRKEERRITYYREKE-EEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKL 851
Query: 236 KDRDRQK 242
++ +R+K
Sbjct: 852 EEVERKK 858
Score = 57.0 bits (136), Expect = 2e-08
Identities = 60/211 (28%), Positives = 88/211 (41%), Gaps = 19/211 (9%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRK-RDRERQRWR--DRDRKRERWGDR 114
R R + +R R + R R ++ DR +R D ER WR D DR R D
Sbjct: 1016 RPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDD 1075
Query: 115 DRETETERQEERERQR----DRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETE 170
DR ++R +R DR + + R G+D DR D DR G E
Sbjct: 1076 DRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRG-AE 1134
Query: 171 RYRDRERERQKQRETRR-DRDRERQREKEDRERD----------RDRQKEREKDRYRERE 219
R R R +RR D DR +R + R R+++K RE+ RE
Sbjct: 1135 DDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRE 1194
Query: 220 TGRDRDKERDRERQREKDRDRQKAIDCVPGR 250
+ ++E DRE++R++D ++ D P R
Sbjct: 1195 SRPSEEREWDREKERDRDNQDREENDKDPER 1225
Score = 56.2 bits (134), Expect = 3e-08
Identities = 47/197 (23%), Positives = 103/197 (52%), Gaps = 18/197 (9%)
Query: 60 RERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETE 119
+E QR R++ + + R + I+++++ +R+ E Q+ R + +R R ++RE E
Sbjct: 563 KEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKE 622
Query: 120 TERQEERERQRDRKREKDRERQRQREIGID--KDREIETEKDRDRE----REMGETERYR 173
QE + ++ RE+ E+ ++ E+G KD +IE ++ D + +++ + E+ +
Sbjct: 623 RILQEHEQIKKKTVRER-LEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEK 681
Query: 174 DRERERQKQRETRRDR-DRERQRE---------KEDRERDRDRQKEREKDRYRERETGRD 223
+ER K +E + D +R ++ E +E R +D D +++E++R + R+
Sbjct: 682 KELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLERE 741
Query: 224 RDKE-RDRERQREKDRD 239
+ E ++R + +DRD
Sbjct: 742 KALEHKNRMSRMLEDRD 758
Score = 55.1 bits (131), Expect = 7e-08
Identities = 55/205 (26%), Positives = 82/205 (40%), Gaps = 23/205 (11%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDR--------DRQRKR----DRERQRWRDRDR 106
+R +R+ ER R+ + RE + DR DR +R DR +R D D
Sbjct: 927 DRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDD- 985
Query: 107 KRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREM 166
R W + D + R + +R R + DR +R G+D+DR D DR
Sbjct: 986 -RPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRR----GLDEDRGSWRTADEDRGPRR 1040
Query: 167 GETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDK 226
G + R +R + R+ D +R R D DR R D +R R D
Sbjct: 1041 GMDDDRGPRRGGADDERSSWRNADDDRGPR---RGLDDDRGPRRGMD--DDRGPRRGMDD 1095
Query: 227 ERDRERQREKDRDRQKAIDCVPGRW 251
+R R + DR ++ +D G W
Sbjct: 1096 DRGPRRGMDDDRGPRRGLDDDRGPW 1120
Score = 54.7 bits (130), Expect = 9e-08
Identities = 64/238 (26%), Positives = 92/238 (38%), Gaps = 35/238 (14%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWR--DRDRKRERWGDRD 115
RE + + +R +R + R R E+DR +R D +R WR D DR R D D
Sbjct: 946 REPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADED 1005
Query: 116 ----RETETERQEERERQRDRKREKDRERQRQREIGIDKDR-------EIETEKDRDRER 164
R + +R R DR + + R G+D DR + E R+ +
Sbjct: 1006 RGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADD 1065
Query: 165 EMGETERYRDRERERQKQRETR-----RDRDRERQREKED-----RERDRDRQKEREKD- 213
+ G D R+ + R D DR +R +D R D DR R D
Sbjct: 1066 DRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADD 1125
Query: 214 -----RYRERETGRDRDKERDR-ERQREKDRDRQKAIDCVPGRWEVTVMAVDCVPGRW 265
R E + G R+ + DR R+ + DR ++ D PG W V PG W
Sbjct: 1126 DRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVK-----PGGW 1178
Score = 53.9 bits (128), Expect = 2e-07
Identities = 55/224 (24%), Positives = 106/224 (47%), Gaps = 39/224 (17%)
Query: 57 IRERERQRERERQRKRAKERHREKDREIEKDRDRQR-----KRDRERQRWRDRDRKRERW 111
+R+ E +R R+ ++R KER ++ +I+K R+R K + + ++D D +
Sbjct: 604 VRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEE 663
Query: 112 GDRD-------RETETERQEERERQRDRKREKD--RERQRQREIGIDKDREIETEKDRDR 162
D D + E E++E +ER ++++++ D +R EI + K E ++ +D
Sbjct: 664 LDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSA-YEEQRIKDM 722
Query: 163 ER-EMGETERYRDRERERQKQRETRR-------DRD--------------RERQREKEDR 200
+ E E ER + ER+K E + DRD E+ ++ E+R
Sbjct: 723 DLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEER 782
Query: 201 --ERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQK 242
E +R +ER++ R ER R+KE + +R+ E+ +++
Sbjct: 783 LAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKER 826
Score = 43.1 bits (100), Expect = 3e-04
Identities = 39/138 (28%), Positives = 59/138 (42%), Gaps = 36/138 (26%)
Query: 30 SWRLAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDR------- 82
SWR + R DRD +R R+R+ R + ++ ++DR
Sbjct: 1258 SWRDSSRRDDRDRD---------------DRRRERDDRRDLRERRDLRDDRDRRGPPLRS 1302
Query: 83 EIEKDRDRQRKRDRERQRWRDRDR---------KRERWGDRDRETETERQEERERQRDRK 133
E E+ +R DR+ R +RD R+R DRDRE E E+++ R
Sbjct: 1303 EREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWR----- 1357
Query: 134 REKDRERQRQREIGIDKD 151
EKDRE R+ + D+D
Sbjct: 1358 AEKDRESLRRTKNETDED 1375
Score = 37.0 bits (84), Expect = 0.020
Identities = 19/87 (21%), Positives = 47/87 (54%), Gaps = 5/87 (5%)
Query: 158 KDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRE 217
++++ + ++ T ++ +E Q+ R+ + E+++R + Q+E+E+ RE
Sbjct: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIE-----ERKERLESLNIQREKEELEQRE 598
Query: 218 RETGRDRDKERDRERQREKDRDRQKAI 244
E + R E +R RQ K+R++++ +
Sbjct: 599 AELQKVRKAEEERLRQEAKEREKERIL 625
Score = 35.4 bits (80), Expect = 0.058
Identities = 28/110 (25%), Positives = 54/110 (49%), Gaps = 5/110 (4%)
Query: 138 RERQRQREIGID---KDREIETEKDRDREREMGET-ERYRDRERERQKQRETRRDRDRER 193
+E++ Q ++ + K+ E ++ R + + E ER +R+K+ +R+ + ++
Sbjct: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQK 603
Query: 194 QREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKA 243
R+ E+ ER R KEREK+R + + R+R Q +K KA
Sbjct: 604 VRKAEE-ERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKA 652
Score = 32.7 bits (73), Expect = 0.37
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 15/78 (19%)
Query: 30 SWRLA---MRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKER---HREKDRE 83
SWR A ++E+RD R P R+R+R+R+R+R+ KE+ EKDRE
Sbjct: 1309 SWRRADDRKDDRVEERDP-----PRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRE 1363
Query: 84 IEKDRDRQRKRDRERQRW 101
R+ K + + W
Sbjct: 1364 ----SLRRTKNETDEDGW 1377
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 88.2 bits (217), Expect = 7e-18
Identities = 57/211 (27%), Positives = 92/211 (43%), Gaps = 7/211 (3%)
Query: 57 IRERERQRERERQRKRAK-ERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRD 115
+++ R +++ K+ K E H +K+ +K R+R + R + ++RK R
Sbjct: 8 LKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
Query: 116 RETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDR 175
R ER R R R R+R+K R R R+R+ + RE + + R RER+ R R R
Sbjct: 68 RSRSRER---RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 124
Query: 176 ERERQKQRETRRDRDRERQREK---EDRERDRDRQKEREKDRYRERETGRDRDKERDRER 232
R R + R R R R R R+K + R R + +R R T D + R
Sbjct: 125 SRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRL 184
Query: 233 QREKDRDRQKAIDCVPGRWEVTVMAVDCVPG 263
+R K Q+ + V + + + A G
Sbjct: 185 ERAKKLQEQREKEMVEKQKQQEIAAAAATGG 215
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 87.8 bits (216), Expect = 1e-17
Identities = 59/220 (26%), Positives = 130/220 (59%), Gaps = 19/220 (8%)
Query: 31 WRLAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDR 90
WR R + +++++ R +RE++ RE+E Q + +E+ E++ EK R++
Sbjct: 317 WRQEKRLREQEKEL------REQEKELREQKELREQEEQMQEQEEKMWEQE---EKMREQ 367
Query: 91 QRKRDRERQR-WRDRDRKRERWGD-RDRETETERQEERERQRD-RKREKDRERQRQREIG 147
+ K R+ +R W + RE+ RD+E Q+ER R+++ R RE+++ ++ ++
Sbjct: 368 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMR 427
Query: 148 IDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKED--RERDRD 205
+K + + +K RD+E +M E ER R+RE++ +++ ET R+++ + Q+++E+ + +++
Sbjct: 428 EEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 487
Query: 206 RQKER---EKDRYRERETGRDRDKERDRERQREKDRDRQK 242
Q++R +K++ E+E + +++E Q EK RD+++
Sbjct: 488 WQQQRLPEQKEKLWEQE--KMQEQEEKIWEQEEKIRDQEE 525
Score = 85.5 bits (210), Expect = 5e-17
Identities = 62/210 (29%), Positives = 120/210 (57%), Gaps = 15/210 (7%)
Query: 57 IRERERQ-RERERQRKRAKERHREKD---REIEKDRDRQRKRDRERQRWRDRDRKRERWG 112
+RE+E++ R++E + R +ER RE++ RE E+ RQ KR RE+++ K R
Sbjct: 281 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQ 340
Query: 113 DRDRETETERQEERER---QRDRKREKDRERQRQREIGIDKDREI--ETEKDRDREREMG 167
RE E + QE+ E+ Q ++ RE++ + RQ E ++++++ + +K RD+E M
Sbjct: 341 KELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 400
Query: 168 E-TERYRDRE---RERQKQ-RETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGR 222
E ER R++E RE++K + + R+ ++ +E+E + RD++ +K +E++R RERE
Sbjct: 401 EQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQE-EKMQEEERIREREKKM 459
Query: 223 DRDKERDRERQREKDRDRQKAIDCVPGRWE 252
++E RE++ + + + + W+
Sbjct: 460 REEEETMREQEEKMQKQEENMWEQEEKEWQ 489
Score = 83.6 bits (205), Expect = 2e-16
Identities = 56/190 (29%), Positives = 109/190 (57%), Gaps = 13/190 (6%)
Query: 58 RERERQRERERQ-RKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGD-RD 115
R+ E RE+E++ RK+ ++ R+++R E++ + R++E + WR R RE+ + R+
Sbjct: 276 RQEEELREQEKKIRKQEEKMWRQEERLREQEG---KMREQEEKMWRQEKRLREQEKELRE 332
Query: 116 RETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDR 175
+E E Q+E Q ++ +E++ + Q E K RE E + R ER + ++ R++
Sbjct: 333 QEKELREQKELREQEEQMQEQEEKMWEQEE----KMREQEEKMWRQEERLWEQEKQMREQ 388
Query: 176 ERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRE---R 232
E++ + Q E ++D ER REKE+R R++++ E+ + E++ K RD+E +
Sbjct: 389 EQKMRDQEERMWEQD-ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQ 447
Query: 233 QREKDRDRQK 242
+ E+ R+R+K
Sbjct: 448 EEERIREREK 457
Score = 80.5 bits (197), Expect = 2e-15
Identities = 53/216 (24%), Positives = 118/216 (54%), Gaps = 20/216 (9%)
Query: 57 IRERER---QRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGD 113
+RE+E+ Q E+ R+ K+ +E+ ++ + EK ++ +R R+RE++ + + RE+
Sbjct: 413 MREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK 472
Query: 114 RDRETETE-RQEERE-------RQRDRKREKDRERQRQREIGIDKDREIETEKDRDRERE 165
++ E QEE+E Q+++ E+++ ++++ +I +++ + E+ +E++
Sbjct: 473 MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 532
Query: 166 MGETERYRDRERERQKQRETRRDR-----DRERQREKEDRERDR----DRQKEREKDRYR 216
M E+ R++E + +Q E RD+ D+E + EK+ +E+++ +K RE++R R
Sbjct: 533 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMR 592
Query: 217 ERETGRDRDKERDRERQREKDRDRQKAIDCVPGRWE 252
ERE ++E RE++ + +K + WE
Sbjct: 593 EREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWE 628
Score = 80.5 bits (197), Expect = 2e-15
Identities = 42/196 (21%), Positives = 110/196 (56%), Gaps = 2/196 (1%)
Query: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
+E+E++ + ++ R +ER RE+++++ ++ + R+++ + Q ++ +++E E
Sbjct: 572 QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEE 631
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRER 177
E++E+ Q ++ E++ + Q+ + K++ E EK +++E+ + E+ ++E+
Sbjct: 632 KMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEK 691
Query: 178 -ERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREK 236
E++ Q + ++ D+E+ RE+E R+R+++ E++ RE+E +E+ +E++ E
Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESM-REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEM 750
Query: 237 DRDRQKAIDCVPGRWE 252
+K + WE
Sbjct: 751 WEQEEKMWEQEEKMWE 766
Score = 80.1 bits (196), Expect = 2e-15
Identities = 51/222 (22%), Positives = 119/222 (53%), Gaps = 7/222 (3%)
Query: 59 ERERQ-RERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
E+E+Q RE+E++ + +ER E+D + + +R R++++ W ++ RE +++E
Sbjct: 380 EQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK---MWEQVEKMREEKKMQEQE 436
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRER 177
+T QEE+ ++ +R RE++++ + + E +++ +++ +++ E+E E ++ R E+
Sbjct: 437 KKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 496
Query: 178 ERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKD 237
+ + + + E+ E+E++ RD++ +EK +R+ + R++E Q EK
Sbjct: 497 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM---REQEDQMWEQEEKM 553
Query: 238 RDRQKAIDCVPGRWEVTVMAVDCVPGRWEVTVGDGRRLRARE 279
RD+++ + R E + E + + R+R RE
Sbjct: 554 RDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRERE 595
Score = 78.6 bits (192), Expect = 6e-15
Identities = 42/186 (22%), Positives = 111/186 (59%), Gaps = 8/186 (4%)
Query: 60 RERQRERERQRKRAKERHREKDREI--EKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
+E+ RE+E Q +E+ R++++++ +++R ++ +++E++ W ++ RE R+RE
Sbjct: 536 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRERE 595
Query: 118 TETERQEERERQRDRKREKDRERQRQREIGI---DKDREIETEKDRDREREMGETER--Y 172
+ +EE R+++ K ++ E+ +++E + ++ + + EK ++E +M E E +
Sbjct: 596 KKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 655
Query: 173 RDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRER 232
+ QK++ ++ +E+++ +E E+ +++K +K + +E++T D++K R+ E
Sbjct: 656 EQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTW-DQEKMREEES 714
Query: 233 QREKDR 238
RE+++
Sbjct: 715 MREREK 720
Score = 78.2 bits (191), Expect = 8e-15
Identities = 54/206 (26%), Positives = 112/206 (54%), Gaps = 14/206 (6%)
Query: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
+ E+ R++E++ +ER +K +E EK Q ++ RE +R R+R++K + RE
Sbjct: 549 QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 608
Query: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDR--- 175
E E+ +E+E + + EK E++ + + +K E E EK ++E +M E +R ++
Sbjct: 609 E-EKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE-EKMWEQEEKMWEQQRLPEQKEK 666
Query: 176 --ERERQKQRETRRDRD----RERQREKEDRERDR---DRQKEREKDRYRERETGRDRDK 226
E E+ +++E ++++ + + EK+ +E+++ D++K RE++ RERE ++
Sbjct: 667 LWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726
Query: 227 ERDRERQREKDRDRQKAIDCVPGRWE 252
E RE++ + +K + WE
Sbjct: 727 EMMREQEEKMQEQEEKMQEQEEEMWE 752
Score = 76.6 bits (187), Expect = 2e-14
Identities = 50/207 (24%), Positives = 114/207 (55%), Gaps = 27/207 (13%)
Query: 57 IRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
IR++E +E++ R ++ ++D+ E++ ++ RD+E++ W +R ++ ++++
Sbjct: 520 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQE---EKMRDQEQKMWDQEERMEKKTQEQEK 576
Query: 117 ET----ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERY 172
+T E R+EER R+R++K ++ E R++E +K +E E + E+ + E+
Sbjct: 577 KTWDQEEKMREEERMREREKKMREEEEMMREQE---EKMQEQEEKMQEQEEKMWEQEEKM 633
Query: 173 RDRERERQKQRETRRDRDR---ERQREKEDRERDRDRQKEREKDRYRERE---------- 219
+++E + +Q E +++ E+QR E +E+ + +K +E+++ +E+E
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKME 693
Query: 220 --TGRDRDKERDRERQREKD--RDRQK 242
T K D+E+ RE++ R+R+K
Sbjct: 694 KKTQEQEKKTWDQEKMREEESMREREK 720
Score = 74.3 bits (181), Expect = 1e-13
Identities = 53/209 (25%), Positives = 122/209 (58%), Gaps = 28/209 (13%)
Query: 58 RERERQRERER-----QRKRAK-ERHREKDR---EIEKDRDRQRKRDRERQ--------R 100
+E++ + + ER +R R K ER RE+++ ++EK R+ ++ +++E++ +
Sbjct: 388 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQ 447
Query: 101 WRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDR 160
+R R+RE+ + ET E++E+ ++Q + E++ + +Q+ + K++ E EK +
Sbjct: 448 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 507
Query: 161 DREREMGE-TERYRDRE----RERQKQRETRRDRDRERQREKEDRERDRDR----QKER- 210
++E ++ E E+ RD+E +E++ R+ + ++ E+E++ RD+++ Q+ER
Sbjct: 508 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM 567
Query: 211 -EKDRYRERETGRDRDKERDRERQREKDR 238
+K + +E++T +K R+ ER RE+++
Sbjct: 568 EKKTQEQEKKTWDQEEKMREEERMREREK 596
Score = 74.3 bits (181), Expect = 1e-13
Identities = 42/217 (19%), Positives = 111/217 (51%), Gaps = 31/217 (14%)
Query: 57 IRERERQRERERQRKRAKERHREKDREIEKDRDR------------QRKRDRERQRWRDR 104
+RE ER RERE++ + +E RE++ ++++ ++ ++ +++E + W
Sbjct: 585 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE 644
Query: 105 DR----------------KRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGI 148
++ ++E+ + ++ E E+ +E+E + + + +++ Q Q +
Sbjct: 645 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTW 704
Query: 149 DKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQK 208
D+++ E E R+RE++M E E + E+ +++E + E E+E++ +++ +
Sbjct: 705 DQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKM 764
Query: 209 EREKDRYRERETGRDRDKERDRER---QREKDRDRQK 242
++ ++E + +K +++E+ Q EK RD+++
Sbjct: 765 WEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEE 801
Score = 72.0 bits (175), Expect = 6e-13
Identities = 48/191 (25%), Positives = 103/191 (53%), Gaps = 11/191 (5%)
Query: 59 ERERQRERERQRKRAKERHR-----EKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGD 113
+ E+ E+E+ K+ +E+ + EK RE E R+R++K E + R+++ K + +
Sbjct: 682 QEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741
Query: 114 RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173
+ +E E E E+ E+ +++ EK E+QR E K++ E EK +++E+ + E+ R
Sbjct: 742 KMQEQEEEMWEQEEKMWEQE-EKMWEQQRLPE---QKEKLWEHEKMQEQEKIWEQEEKMR 797
Query: 174 DRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERET--GRDRDKERDRE 231
D+E + + Q E R ++ + + ++E ++ +E+ + + E G++ E +
Sbjct: 798 DQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQ 857
Query: 232 RQREKDRDRQK 242
Q EK R++++
Sbjct: 858 GQEEKMREQEE 868
Score = 71.2 bits (173), Expect = 9e-13
Identities = 46/191 (24%), Positives = 109/191 (57%), Gaps = 17/191 (8%)
Query: 59 ERERQRERERQRKRAKERHREKDREI--EKDRDRQRK-RDRERQRWRD----RDRKRERW 111
E+E+ +E+E + +E+ R+++ EK RQ K R++E Q W RD++++ W
Sbjct: 502 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 561
Query: 112 GDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETER 171
D++ E + QE+ ++ D++ EK RE +R RE +++++ E++ RE+E E+
Sbjct: 562 -DQEERMEKKTQEQEKKTWDQE-EKMREEERMRE----REKKMREEEEMMREQE----EK 611
Query: 172 YRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRE 231
+++E + Q+Q E +++ + Q ++E ++ E+E+ + ++ ++K + E
Sbjct: 612 MQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHE 671
Query: 232 RQREKDRDRQK 242
+ +E+++ +++
Sbjct: 672 KMQEQEKMQEQ 682
Score = 67.8 bits (164), Expect = 1e-11
Identities = 44/195 (22%), Positives = 107/195 (54%), Gaps = 13/195 (6%)
Query: 57 IRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
+RE E RERE++ + +E RE++ ++++ ++ +++E + W +++ + W ++
Sbjct: 709 MREEESMREREKKMREEEEMMREQEEKMQEQEEKM--QEQEEEMW---EQEEKMWEQEEK 763
Query: 117 ETETER-QEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDR 175
E +R E++E+ + ++ +++E+ ++E +K R+ E + E+ G+ E+ R +
Sbjct: 764 MWEQQRLPEQKEKLWEHEKMQEQEKIWEQE---EKMRDQEEKMRGQEEKMRGQEEKMRGQ 820
Query: 176 ERERQKQRETRRDRDRERQREKE---DRERDRDRQKEREKDRYRERETGRDRDKERDRER 232
E + Q E ++ + ++E +E + + + ++++ RE+E +E+ RE
Sbjct: 821 EEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMRE- 879
Query: 233 QREKDRDRQKAIDCV 247
Q EK R +++ I CV
Sbjct: 880 QEEKMRGQEEKIYCV 894
Score = 62.8 bits (151), Expect = 3e-10
Identities = 34/164 (20%), Positives = 100/164 (60%), Gaps = 10/164 (6%)
Query: 61 ERQRERERQRKRAKERHREKDREI-EKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETE 119
++++ E ++ + +E+ +E++ +I E+++ ++ +++E++ W D+++ RE R+RE +
Sbjct: 663 QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTW-DQEKMREEESMREREKK 721
Query: 120 TERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRER-- 177
+EE R+++ K ++ E+ +++E ++ + EK ++E +M E +R +++
Sbjct: 722 MREEEEMMREQEEKMQEQEEKMQEQE----EEMWEQEEKMWEQEEKMWEQQRLPEQKEKL 777
Query: 178 -ERQKQRETRRDRDRE-RQREKEDRERDRDRQKEREKDRYRERE 219
E +K +E + ++E + R++E++ R ++ + ++++ R +E
Sbjct: 778 WEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821
Score = 62.0 bits (149), Expect = 6e-10
Identities = 54/229 (23%), Positives = 111/229 (48%), Gaps = 24/229 (10%)
Query: 33 LAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRD--- 89
++ R + DR + L R A ++ R E ++K A+ + + E EK
Sbjct: 188 VSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLN 247
Query: 90 -RQRKRDRERQRW-----RDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQ 143
++ KR ER ++ + + E W +E E QE++ R+++ K + ER R+
Sbjct: 248 VKELKRKLERAKFLLPQVQTNTLQEEMWR---QEEELREQEKKIRKQEEKMWRQEERLRE 304
Query: 144 REIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERD 203
+E K R++E +M E+ R RE+E++ + + + R+++ RE+E++ ++
Sbjct: 305 QE-----------GKMREQEEKMWRQEK-RLREQEKELREQEKELREQKELREQEEQMQE 352
Query: 204 RDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAIDCVPGRWE 252
++ + ++++ RE+E R +ER E++++ QK D WE
Sbjct: 353 QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE 401
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,836,388
Number of Sequences: 37866
Number of extensions: 598006
Number of successful extensions: 57972
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1113
Number of HSP's successfully gapped in prelim test: 670
Number of HSP's that attempted gapping in prelim test: 7155
Number of HSP's gapped (non-prelim): 16172
length of query: 285
length of database: 18,247,518
effective HSP length: 101
effective length of query: 184
effective length of database: 14,423,052
effective search space: 2653841568
effective search space used: 2653841568
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.