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Search of human proteins with 168229156
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|168229156 NFKB activating protein [Homo sapiens]
(415 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|168229156 NFKB activating protein [Homo sapiens] 823 0.0
gi|56090620 NFKB activating protein-like [Homo sapiens] 452 e-127
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 90 4e-18
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 90 4e-18
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 88 2e-17
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 79 8e-15
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 78 1e-14
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 76 6e-14
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 76 6e-14
gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens] 74 2e-13
gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens] 74 2e-13
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 74 2e-13
gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens] 74 3e-13
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 73 5e-13
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 72 7e-13
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 72 9e-13
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 72 9e-13
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 72 1e-12
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 70 4e-12
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 69 1e-11
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 69 1e-11
gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo ... 68 1e-11
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 68 2e-11
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 68 2e-11
gi|27883882 P18SRP protein [Homo sapiens] 67 2e-11
gi|4557509 cylicin 2 [Homo sapiens] 66 7e-11
gi|50962882 G patch domain containing 8 [Homo sapiens] 65 1e-10
gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens] 64 2e-10
gi|40068059 CBF1 interacting corepressor [Homo sapiens] 64 3e-10
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 63 6e-10
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 823 bits (2125), Expect = 0.0
Identities = 415/415 (100%), Positives = 415/415 (100%)
Query: 1 MAPVSGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQL 60
MAPVSGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQL
Sbjct: 1 MAPVSGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQL 60
Query: 61 GGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDK 120
GGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDK
Sbjct: 61 GGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDK 120
Query: 121 EREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEE 180
EREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEE
Sbjct: 121 EREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEE 180
Query: 181 EKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEK 240
EKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEK
Sbjct: 181 EKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEK 240
Query: 241 KKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSDLIGPEAPKTLT 300
KKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSDLIGPEAPKTLT
Sbjct: 241 KKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSDLIGPEAPKTLT 300
Query: 301 SQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMSGSRHR 360
SQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMSGSRHR
Sbjct: 301 SQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMSGSRHR 360
Query: 361 RMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILASFREMVYRKTKGKDDK 415
RMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILASFREMVYRKTKGKDDK
Sbjct: 361 RMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILASFREMVYRKTKGKDDK 415
>gi|56090620 NFKB activating protein-like [Homo sapiens]
Length = 402
Score = 452 bits (1164), Expect = e-127
Identities = 266/420 (63%), Positives = 308/420 (73%), Gaps = 23/420 (5%)
Query: 1 MAPVSGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRN--GLTH 58
M PVS S S + GS RRRSSS SP SP+ R S CSRS R GL
Sbjct: 1 MPPVSRS-SYSEDIVGSRRRRRSSSGSPP------SPQSRCSSWDGCSRSHSRGREGLRP 53
Query: 59 QLGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLL 118
L G+ SRS SR R R FAS+ S+ Y G + + S
Sbjct: 54 PWSELDVGALYPF----SRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAE 109
Query: 119 DKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEP---KKSTTSA 175
D E+EES RQ+RL ERERIGELGAPEVWG SPK P+ DSDEHTPVEDEE +KS++S
Sbjct: 110 DYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSD 169
Query: 176 STSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKA 235
S SEE +KKK+SRS R+KK+RK KSSKRKH+KYS DSDS+S+S+T+S +D+K+R K A
Sbjct: 170 SNSEEHRKKKTSRS--RNKKKRKNKSSKRKHRKYS-DSDSNSESDTNSDSDDDKKRVK-A 225
Query: 236 KKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSDLIGPEA 295
KKK+KKKKH++KK K++KK++KESSDSS K+S+E+ E W ++ + DLIGPEA
Sbjct: 226 KKKKKKKKHKTKK---KKNKKTKKESSDSSCKDSEEDLSEATWMEQPNVADTMDLIGPEA 282
Query: 296 PKTLTSQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMS 355
P TSQD+KPL YGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEI SFECSGYVMS
Sbjct: 283 PIIHTSQDEKPLKYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIGSFECSGYVMS 342
Query: 356 GSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILASFREMVYRKTKGKDDK 415
GSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRE+KILASFREMV++KTK KDDK
Sbjct: 343 GSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRESKILASFREMVHKKTKEKDDK 402
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 89.7 bits (221), Expect = 4e-18
Identities = 84/306 (27%), Positives = 130/306 (42%), Gaps = 55/306 (17%)
Query: 7 SRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQG 66
SRS +R S RRRS S K SKS R R RSRSHS + D + + +
Sbjct: 335 SRSHNRSRSRQKDRRRSKSPHKKRSKS-RERRKSRSRSHSRDKRKDTREKIKEKERVKEK 393
Query: 67 SRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESL 126
R + R R + R +E+ R D+ DKERE+
Sbjct: 394 DREKE-REREKEREKEK---------------------ERGKNKDR------DKEREKDR 425
Query: 127 RQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKS 186
+ + +RER E K E D D+ E ++ K+ S +EK+KK
Sbjct: 426 EKDKEKDRERERE-----------KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD 474
Query: 187 SRSKE-----RSKKRRKKKSSKRKHKKYSEDSDSDSDSET----DSSDEDNKRRAKKAKK 237
+S+ + +R + S +R+ ++ S S S+T S + R KK KK
Sbjct: 475 KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKK 534
Query: 238 KEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSDLIGPE--- 294
+EK++ H S++ +++RS RK S+D KE E+ K++ +EP + E
Sbjct: 535 REKERDHISERRERERSTSMRKSSNDRDGKEKLEK-NSTSLKEKEHNKEPDSSVSKEVDD 593
Query: 295 --APKT 298
AP+T
Sbjct: 594 KDAPRT 599
Score = 75.5 bits (184), Expect = 8e-14
Identities = 72/273 (26%), Positives = 112/273 (41%), Gaps = 64/273 (23%)
Query: 4 VSGSRSPDREASGS--GGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLG 61
+S + P+ S GGR RS ++S S+S+ RR RS S RS N
Sbjct: 289 ISAAIEPESGKSNERKGGRSRSHTRSK--SRSSSKSHSRRKRSQSKHRSRSHN------- 339
Query: 62 GLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKE 121
RSRSR + R R +P + S S SR + DK
Sbjct: 340 -----------RSRSRQKDRRRSKSPHK---KRSKSRERRKSRSRSHSRDK--------- 376
Query: 122 REESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEE 181
R+++ ++++ E+ER+ E +D E ++ E+E
Sbjct: 377 RKDT--REKIKEKERVKE------------------------KDREKEREREKEREKEKE 410
Query: 182 KKKKSSRSKERSKKRRKKKSSKR---KHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKK 238
+ K R KER K R K K R + K++ +D D + + E D E K R+K+ +K
Sbjct: 411 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 470
Query: 239 EKK-KKHRSKKYKKKRSKKSRKESSDSSSKESQ 270
KK KK R+ S++SR S + + S+
Sbjct: 471 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSR 503
Score = 63.9 bits (154), Expect = 3e-10
Identities = 43/173 (24%), Positives = 81/173 (46%), Gaps = 3/173 (1%)
Query: 115 PSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTS 174
P KE EE + KR+ E + G S + S HT + KS +
Sbjct: 268 PQAAAKELEEVM--KRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR 325
Query: 175 ASTSEEEKKKKS-SRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAK 233
S+ + + +S +RS+ R K RR+ KS +K K E S S S + +D + + K
Sbjct: 326 RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIK 385
Query: 234 KAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
+ ++ ++K + + ++ +K+R K+ + + KE +++ ++ KDR + E
Sbjct: 386 EKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE 438
Score = 57.4 bits (137), Expect = 2e-08
Identities = 32/142 (22%), Positives = 67/142 (47%), Gaps = 2/142 (1%)
Query: 164 EDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDS 223
+ + +S + + ++++++ S K+RSK R ++KS R H + + E +
Sbjct: 330 QSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER 389
Query: 224 SDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTK 283
E ++ + ++ +K+ +K+K R K K R K+ K+ K+ + E + KDR K
Sbjct: 390 VKEKDREKEREREKEREKEKERGK--NKDRDKEREKDREKDKEKDREREREKEHEKDRDK 447
Query: 284 AEEPSDLIGPEAPKTLTSQDDK 305
+E E K + + D+
Sbjct: 448 EKEKEQDKEKEREKDRSKEIDE 469
Score = 39.7 bits (91), Expect = 0.005
Identities = 25/117 (21%), Positives = 52/117 (44%)
Query: 167 EPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDE 226
+P + T A+ E E+ K R + + S + +++ S S + S++ SS +
Sbjct: 262 KPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSK 321
Query: 227 DNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTK 283
+ RR + K + +RS+ +K R + S S+E ++ + +D+ K
Sbjct: 322 SHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRK 378
Score = 35.4 bits (80), Expect = 0.096
Identities = 48/220 (21%), Positives = 76/220 (34%), Gaps = 24/220 (10%)
Query: 8 RSPDREASGSGGRRRSSSKSPKPSKSARSPRGR---RSRSHSCSRSGDRNGLTHQLGGLS 64
R DRE R R K + + + + + R S+ D +
Sbjct: 421 REKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP 480
Query: 65 QGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREE 124
S N S RSRS SR R R + S+S S + S P P +K+ +
Sbjct: 481 PRSYNASRRSRSSSRERRRRRS------RSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK- 533
Query: 125 SLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKK 184
KR ER+ I E + E + D + K+ STS +EK+
Sbjct: 534 ----KREKERDHISER----------RERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEH 579
Query: 185 KSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSS 224
SK+ K + + + K + + + E S+
Sbjct: 580 NKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLST 619
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 89.7 bits (221), Expect = 4e-18
Identities = 84/306 (27%), Positives = 130/306 (42%), Gaps = 55/306 (17%)
Query: 7 SRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQG 66
SRS +R S RRRS S K SKS R R RSRSHS + D + + +
Sbjct: 219 SRSHNRSRSRQKDRRRSKSPHKKRSKS-RERRKSRSRSHSRDKRKDTREKIKEKERVKEK 277
Query: 67 SRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESL 126
R + R R + R +E+ R D+ DKERE+
Sbjct: 278 DREKE-REREKEREKEK---------------------ERGKNKDR------DKEREKDR 309
Query: 127 RQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKS 186
+ + +RER E K E D D+ E ++ K+ S +EK+KK
Sbjct: 310 EKDKEKDRERERE-----------KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD 358
Query: 187 SRSKE-----RSKKRRKKKSSKRKHKKYSEDSDSDSDSET----DSSDEDNKRRAKKAKK 237
+S+ + +R + S +R+ ++ S S S+T S + R KK KK
Sbjct: 359 KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKK 418
Query: 238 KEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSDLIGPE--- 294
+EK++ H S++ +++RS RK S+D KE E+ K++ +EP + E
Sbjct: 419 REKERDHISERRERERSTSMRKSSNDRDGKEKLEK-NSTSLKEKEHNKEPDSSVSKEVDD 477
Query: 295 --APKT 298
AP+T
Sbjct: 478 KDAPRT 483
Score = 75.5 bits (184), Expect = 8e-14
Identities = 72/273 (26%), Positives = 112/273 (41%), Gaps = 64/273 (23%)
Query: 4 VSGSRSPDREASGS--GGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLG 61
+S + P+ S GGR RS ++S S+S+ RR RS S RS N
Sbjct: 173 ISAAIEPESGKSNERKGGRSRSHTRSK--SRSSSKSHSRRKRSQSKHRSRSHN------- 223
Query: 62 GLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKE 121
RSRSR + R R +P + S S SR + DK
Sbjct: 224 -----------RSRSRQKDRRRSKSPHK---KRSKSRERRKSRSRSHSRDK--------- 260
Query: 122 REESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEE 181
R+++ ++++ E+ER+ E +D E ++ E+E
Sbjct: 261 RKDT--REKIKEKERVKE------------------------KDREKEREREKEREKEKE 294
Query: 182 KKKKSSRSKERSKKRRKKKSSKR---KHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKK 238
+ K R KER K R K K R + K++ +D D + + E D E K R+K+ +K
Sbjct: 295 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 354
Query: 239 EKK-KKHRSKKYKKKRSKKSRKESSDSSSKESQ 270
KK KK R+ S++SR S + + S+
Sbjct: 355 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSR 387
Score = 63.9 bits (154), Expect = 3e-10
Identities = 43/173 (24%), Positives = 81/173 (46%), Gaps = 3/173 (1%)
Query: 115 PSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTS 174
P KE EE + KR+ E + G S + S HT + KS +
Sbjct: 152 PQAAAKELEEVM--KRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR 209
Query: 175 ASTSEEEKKKKS-SRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAK 233
S+ + + +S +RS+ R K RR+ KS +K K E S S S + +D + + K
Sbjct: 210 RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIK 269
Query: 234 KAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
+ ++ ++K + + ++ +K+R K+ + + KE +++ ++ KDR + E
Sbjct: 270 EKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE 322
Score = 57.4 bits (137), Expect = 2e-08
Identities = 32/142 (22%), Positives = 67/142 (47%), Gaps = 2/142 (1%)
Query: 164 EDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDS 223
+ + +S + + ++++++ S K+RSK R ++KS R H + + E +
Sbjct: 214 QSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER 273
Query: 224 SDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTK 283
E ++ + ++ +K+ +K+K R K K R K+ K+ K+ + E + KDR K
Sbjct: 274 VKEKDREKEREREKEREKEKERGK--NKDRDKEREKDREKDKEKDREREREKEHEKDRDK 331
Query: 284 AEEPSDLIGPEAPKTLTSQDDK 305
+E E K + + D+
Sbjct: 332 EKEKEQDKEKEREKDRSKEIDE 353
Score = 39.7 bits (91), Expect = 0.005
Identities = 25/117 (21%), Positives = 52/117 (44%)
Query: 167 EPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDE 226
+P + T A+ E E+ K R + + S + +++ S S + S++ SS +
Sbjct: 146 KPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSK 205
Query: 227 DNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTK 283
+ RR + K + +RS+ +K R + S S+E ++ + +D+ K
Sbjct: 206 SHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRK 262
Score = 35.4 bits (80), Expect = 0.096
Identities = 48/220 (21%), Positives = 76/220 (34%), Gaps = 24/220 (10%)
Query: 8 RSPDREASGSGGRRRSSSKSPKPSKSARSPRGR---RSRSHSCSRSGDRNGLTHQLGGLS 64
R DRE R R K + + + + + R S+ D +
Sbjct: 305 REKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP 364
Query: 65 QGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREE 124
S N S RSRS SR R R + S+S S + S P P +K+ +
Sbjct: 365 PRSYNASRRSRSSSRERRRRRS------RSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK- 417
Query: 125 SLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKK 184
KR ER+ I E + E + D + K+ STS +EK+
Sbjct: 418 ----KREKERDHISER----------RERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEH 463
Query: 185 KSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSS 224
SK+ K + + + K + + + E S+
Sbjct: 464 NKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLST 503
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 87.8 bits (216), Expect = 2e-17
Identities = 90/294 (30%), Positives = 129/294 (43%), Gaps = 40/294 (13%)
Query: 5 SGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLS 64
S SRS RE GS R + + + R + R + SRS DR GL
Sbjct: 276 SRSRSHHREGHGSSSFDRELEREKERQRLEREAK-EREKERRRSRSIDR--------GLE 326
Query: 65 QGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREE 124
+ R RSRSRSR+R R + R Y DK + +KERE
Sbjct: 327 RRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDY--DKERGNEREKERER 384
Query: 125 SLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKK 184
S ++R E+ GE+ K + D D+ +D+ K S S ++K
Sbjct: 385 S--RERSKEQRSRGEV--------EEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERK 434
Query: 185 KSSRSK-----ERSKKRRKKKSSKRKH---KKYSEDSDSDSDSETDSSDEDNKRRAKKAK 236
SRS+ +RS+ R K+KSSK K+ +K ++ S S S TDS ++ KR +K
Sbjct: 435 HRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSK 494
Query: 237 KKEKKKKHRSKKYKKKRSKKSRKESSD--------SSSKESQEEFLENPWKDRT 282
+K +K+ RSK+ KR K+ SD S +ESQE+ +N KD T
Sbjct: 495 EKSRKRS-RSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKN--KDET 545
Score = 73.6 bits (179), Expect = 3e-13
Identities = 69/272 (25%), Positives = 112/272 (41%), Gaps = 48/272 (17%)
Query: 22 RSSSKSPKPSKSAR-SPRGRRSRSHSCSRSGDRNGLTHQLGGLSQGSRNQSYRSRSRSRS 80
R S+SP+ S S R SPR RSRSH R G H + + R R +
Sbjct: 257 RRRSRSPRRSLSPRRSPRRSRSRSHH------REG--HGSSSFDRELEREKERQRLEREA 308
Query: 81 RERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKRLSERERIGEL 140
+ER R S S+ G L++ R S + R R R
Sbjct: 309 KEREKERR------RSRSIDRG---------------LERRRSRSRERHRSRSRSR---- 343
Query: 141 GAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSE-EEKKKKSSRSKERSKKRRKK 199
K D D E+E ++ E++K+ RS+ERSK++R +
Sbjct: 344 --------DRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSR 395
Query: 200 KSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRK 259
+ + KK+ ED D D D+K+ K ++ + +++KHRS+ + K+SR
Sbjct: 396 --GEVEEKKHKEDKD---DRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRS 450
Query: 260 ESSDSSSKESQEEFLENPWKDRTKAEEPSDLI 291
S + SSK E ++ + R+ ++ +D +
Sbjct: 451 RSKEKSSKHKNESKEKSNKRSRSGSQGRTDSV 482
Score = 39.7 bits (91), Expect = 0.005
Identities = 30/143 (20%), Positives = 57/143 (39%), Gaps = 4/143 (2%)
Query: 148 LSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEE----KKKKSSRSKERSKKRRKKKSSK 203
L P+ P P P+K EE +++ SRS RS R+
Sbjct: 217 LFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRS 276
Query: 204 RKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSD 263
R + E S S +++ +R ++AK++EK+++ + ++SR
Sbjct: 277 RSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERH 336
Query: 264 SSSKESQEEFLENPWKDRTKAEE 286
S S++ + +DR + +E
Sbjct: 337 RSRSRSRDRKGDRRDRDREREKE 359
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 79.0 bits (193), Expect = 8e-15
Identities = 77/275 (28%), Positives = 123/275 (44%), Gaps = 41/275 (14%)
Query: 12 REASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQGSRNQS 71
R S S RS S+S + S+ +RS G SHS SRS R+G SR++S
Sbjct: 183 RSYSRSRSHSRSRSRS-RHSRKSRSRSGSSKSSHSKSRSRSRSG---------SRSRSKS 232
Query: 72 YRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKRL 131
RSRS+SRSR + R S S SR + + K + + + ++++
Sbjct: 233 -RSRSQSRSRSKKEKSR--------SPSKEKSRSRSHSAGK------SRSKSKDQAEEKI 277
Query: 132 SERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKS----- 186
+ +G+ + K+ + VE+E K+ + S S+E+ ++S
Sbjct: 278 QNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEE--KRGSVSRGRSQEKSLRQSRSRSR 335
Query: 187 ------SRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETD---SSDEDNKRRAKKAKK 237
SRS+ RSK + K+K KR ++ S S S SE S D+K + K KK
Sbjct: 336 SKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKK 395
Query: 238 KEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEE 272
KE + +S+ + SK+ S+SS +E + E
Sbjct: 396 KEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE 430
Score = 72.4 bits (176), Expect = 7e-13
Identities = 77/292 (26%), Positives = 120/292 (41%), Gaps = 44/292 (15%)
Query: 5 SGSRSPDREASGSGGRRRSSSKSPKPSKS----ARSPRGRRSRSHSCSRSGDRNGLTHQL 60
S S+S R SGS R +S S+S S+S +RSP +SRS S S R+ Q
Sbjct: 214 SHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQA 273
Query: 61 GGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDK 120
Q + N + +SRS SR + + S S R +K +
Sbjct: 274 EEKIQNNDNVG-KPKSRSPSRHK-----------SKSKSRSRSQERRVEEEKRGSVSRGR 321
Query: 121 EREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEE 180
+E+SLRQ R R + G ++ D + EE + + S S SE
Sbjct: 322 SQEKSLRQSRSRSRSKGGSRSRSR-----SRSKSKDKRKGRKRSREESRSRSRSRSKSER 376
Query: 181 EKKKKSSRSKERSKKRRKKK---------------SSKRKHKKYSEDSDSDSDSETDSSD 225
+K+ S R + ++KKK S +R+H K SE S + E++++
Sbjct: 377 SRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAK-SESSQREGRGESENAG 435
Query: 226 EDNKRRAKKAKKKEKK------KKHRSKKYKKKRSK-KSRKESSDSSSKESQ 270
+ + R++ + K + RSK K RS+ KSR S+ S S+
Sbjct: 436 TNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSR 487
Score = 65.5 bits (158), Expect = 9e-11
Identities = 83/326 (25%), Positives = 131/326 (40%), Gaps = 23/326 (7%)
Query: 54 NGLTHQLGGLSQGSRNQSYRSRSRSRSRERPSA-----PRGIPFASASSSVYYGSYSRPY 108
NG +L GSR + SRSRS SR R + R +S SS S SR
Sbjct: 166 NGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSG 225
Query: 109 GSDKPWPSLLDKEREESLRQKRLS---ERERIGELGAPEVWGLSPKNPEPDSDEHTPVED 165
+ + R S ++K S E+ R A G S + ++E D
Sbjct: 226 SRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSA----GKSRSKSKDQAEEKIQNND 281
Query: 166 EEPKKSTTSASTSEEEKKKKSSRSKER--SKKRRKKKSSKRKHKKYSEDSDSDSDSETDS 223
K + S S + K K SRS+ER +++R S R +K S S S S+ S
Sbjct: 282 NVGKPKSRSPS-RHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGS 340
Query: 224 SDEDNKRRAKKAKKKEKKK---KHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKD 280
R K K+K +K+ + RS+ + +S++SRK S SK + + D
Sbjct: 341 RSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTD 400
Query: 281 RTKAEEPSDLIGPEAPKTLTSQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLT 340
R+++ PS + E + S+ + G + E A + ++ R + + L
Sbjct: 401 RSQSRSPSRSVSKER-EHAKSESSQREGRGES----ENAGTNQETRSRSRSNSKSKPNLP 455
Query: 341 SEEIASFECSGYVMSGSRHRRMEAVR 366
SE + + + S S+ R A R
Sbjct: 456 SESRSRSKSASKTRSRSKSRSRSASR 481
Score = 47.0 bits (110), Expect = 3e-05
Identities = 47/214 (21%), Positives = 85/214 (39%), Gaps = 20/214 (9%)
Query: 185 KSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKH 244
K + RS R + S R ++S S S S S S +K R++ + K
Sbjct: 176 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGS---SKSSHSKSRSRSRSGSRSRSKS 232
Query: 245 RSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSDLIGPEAPKTLTSQDD 304
RS+ + RSKK E S S SKE + K R+K+++ +A + + + D+
Sbjct: 233 RSRSQSRSRSKK---EKSRSPSKEKSRSRSHSAGKSRSKSKD-------QAEEKIQNNDN 282
Query: 305 --KPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMSGSRHRRM 362
KP + + + + + + +RG + + S S SR R
Sbjct: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLR-----QSRSRSRSK 337
Query: 363 EAVRLRKENQIYSADEKRALASFNQEERRKRENK 396
R R ++ S D+++ +E R + ++
Sbjct: 338 GGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSR 371
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 78.2 bits (191), Expect = 1e-14
Identities = 85/342 (24%), Positives = 139/342 (40%), Gaps = 45/342 (13%)
Query: 6 GSRSPDREA----SGSGGRRRSSSKSPKPSKS-----ARSPRGRRSRSHSCSRSGDRNGL 56
GS SP +E+ SGS ++R S+S P+K+ +RSP R RS S S + R+
Sbjct: 379 GSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDC- 437
Query: 57 THQLGGLSQGSRNQS-YRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWP 115
SR++S Y++R RSRSR P+ R + + + S SR ++
Sbjct: 438 ----------SRSRSPYKARDRSRSRS-PNKARDHSRSRSPNKARDRSRSRSPSKERDHS 486
Query: 116 SLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKST--T 173
L +E R+ R +ER + S E + P K +
Sbjct: 487 QLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRS 546
Query: 174 SASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAK 233
+ + EE++ + SRS + + RR+ +S ++ ++ S S+ + S + +
Sbjct: 547 QSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYS 606
Query: 234 KAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENP-WK------------- 279
+ + K+K H + K S+ +S S SQ +P WK
Sbjct: 607 RPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNR 666
Query: 280 --DRTKAEEPSDLIGPEAPKTLTSQDDKPLN--YGHALLPGE 317
+T + PS P +TL SQDD + A LPGE
Sbjct: 667 TPSKTSSHSPSTF--PSGGQTL-SQDDSQADATTSKATLPGE 705
Score = 72.0 bits (175), Expect = 9e-13
Identities = 72/299 (24%), Positives = 117/299 (39%), Gaps = 45/299 (15%)
Query: 8 RSPDREASGSGGRRRSSSKSPKPSKSARSPRGR-RSRSHSCSRSGDRNGLTHQLGGLSQG 66
+S ++ ++ S + S S+SP+ S+S R R RSHS R+ R + G LSQ
Sbjct: 267 KSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQM 326
Query: 67 SRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESL 126
R+ RS S+ +S+ + PR G W KER S
Sbjct: 327 GRHSQSRSHSKGKSQNQSRTPRR-------------------GRSHNWSRNPSKERSHSH 367
Query: 127 RQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKS 186
+ ER+ G SP+ S +P + + +S + + + +
Sbjct: 368 SRSSSKERDHRGSS--------SPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSP 419
Query: 187 SRSKERSKKR--RKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKE----- 239
++++RS+ R K + R Y S S S + D R KA+ +
Sbjct: 420 YKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSP 479
Query: 240 -KKKKHR-----SKKYKKKRSKKSRKE----SSDSSSKESQEEFLENPWKDRTKAEEPS 288
K++ H SK+ +RS+ KE S SSSKE +P K+R + + S
Sbjct: 480 SKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRS 538
Score = 52.8 bits (125), Expect = 6e-07
Identities = 74/332 (22%), Positives = 122/332 (36%), Gaps = 67/332 (20%)
Query: 7 SRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQG 66
SRS R + + R + +++ K SK++ +R +HS R+ R G S+
Sbjct: 80 SRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRG--------SRS 131
Query: 67 SRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESL 126
S+ R+ + R R + P +S GS + YG P ++ER +S
Sbjct: 132 SKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGR----PRTSNRERSDS- 186
Query: 127 RQKRLSERE----------RIGELG-------APEVWGLSPK----NPEPDSD------- 158
+ + LS++ R EL G+ K NP P S
Sbjct: 187 QPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYG 246
Query: 159 ---------EHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKY 209
++P E KS AST + + S S+ RS +R + S KR H +
Sbjct: 247 QMIIPSREKSYSPTEMSSRVKSYNQAST----RSRPQSHSQSRSPRRSRSGSQKRTHSRV 302
Query: 210 SEDSDSDSDSETDS-------------SDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKK 256
S + S S S + + K + ++ RS + + SK+
Sbjct: 303 RSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKE 362
Query: 257 SRKESSDSSSKESQEEFLENPWKDRTKAEEPS 288
S SSSKE +P K+ +++ S
Sbjct: 363 RSHSHSRSSSKERDHRGSSSPRKESGRSQSGS 394
Score = 50.1 bits (118), Expect = 4e-06
Identities = 75/326 (23%), Positives = 124/326 (38%), Gaps = 56/326 (17%)
Query: 5 SGSRSPDREASGSGGRR--RSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLG- 61
S R R + S GR R S+S K S S S GR R+H G R G+ ++
Sbjct: 107 SDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGR-IRTH-----GARPGMASRVRT 160
Query: 62 --GLSQGSRNQSY-----RSRSRSRSRERPSA------PRGIPFASASSSVYYGSYSR-- 106
+GSR +SY +R RS S+ R + P G +S S ++
Sbjct: 161 PTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQ 220
Query: 107 -PYG------SDKPWPS----------LLDKEREESLRQKRLSERERIGELGAPEVWGLS 149
P G SD P PS ++ RE+S +S R + + +
Sbjct: 221 TPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQAS------T 274
Query: 150 PKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKK----RRKKKSSKRK 205
P+ S +P + T + K+ SR++ R++K + + S R
Sbjct: 275 RSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRS 334
Query: 206 HKKYSEDSDSDSD----SETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKES 261
H K + S + S S + +R ++ K++ HR +K S +S+ S
Sbjct: 335 HSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGS 394
Query: 262 SDSSSKESQEEFLENPWKDRTKAEEP 287
+ S+ N +DR+++ P
Sbjct: 395 PNKQRDHSRSR-SPNKARDRSRSRSP 419
Score = 38.9 bits (89), Expect = 0.009
Identities = 41/160 (25%), Positives = 62/160 (38%), Gaps = 13/160 (8%)
Query: 153 PEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKK-SSKRKHKKYSE 211
P + V KST S ST + SSRS+ RSK R + S+ + K S+
Sbjct: 46 PTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASK 105
Query: 212 DSDSDSDSE--TDSSDEDNKRRAKKAKKKEKKKKH---RSKKYKKKRSKKSRKESSDSSS 266
SD T S RR ++ K+ + R + + + SR + S
Sbjct: 106 ASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQ 165
Query: 267 KESQEEFLENPWKDRTKAEEPSDLIGPEAPKTLTSQDDKP 306
K S+ + P RT E SD P+ L+ + +P
Sbjct: 166 KGSRGKSYGRP---RTSNRERSD----SQPRNLSKKSYRP 198
Score = 32.3 bits (72), Expect = 0.81
Identities = 18/49 (36%), Positives = 25/49 (51%)
Query: 5 SGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDR 53
S SR+P +E + S R S P S RSP +RS + + S S +R
Sbjct: 618 SRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNR 666
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 75.9 bits (185), Expect = 6e-14
Identities = 62/218 (28%), Positives = 107/218 (49%), Gaps = 38/218 (17%)
Query: 167 EPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDE 226
E K + E+ ++K S S+ SKKR++KK K+K +YS S S SDS + SSD
Sbjct: 52 EEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDS 111
Query: 227 DNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
+++ KK K+ KKKK+RS K + ++ +S DS K+ + KD T+ E+
Sbjct: 112 EDE--DKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKS-------KDGTEKEK 162
Query: 287 PSDLIGPEAPKTLTSQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIAS 346
D+ G + + S +DKPL+ E + +EY++ + ++ +SEE
Sbjct: 163 --DIKGLSKKRKMYS-EDKPLS-------SESLSESEYIEEVRAKKKK-----SSEE--- 204
Query: 347 FECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALAS 384
R + E + +K+++ +S +K+ AS
Sbjct: 205 -----------REKATEKTKKKKKHKKHSKKKKKKAAS 231
Score = 70.9 bits (172), Expect = 2e-12
Identities = 51/178 (28%), Positives = 87/178 (48%), Gaps = 27/178 (15%)
Query: 114 WPSLLDKEREESL---------RQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVE 164
W L+K RE+ L RQ++ E+++ G + + DS++ +
Sbjct: 59 WKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQ 118
Query: 165 DEEPKK--------STTSASTSEEEKK---KKSSRSKERSKKRRKKKSSKRKHKKYSEDS 213
+ KK S +S S +E + K KK +SK+ ++K + K +K K YSED
Sbjct: 119 GKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDK 178
Query: 214 --DSDSDSETDSSDEDNKRRAKKAKKKEK-----KKKHRSKKYKKKRSKKSRKESSDS 264
S+S SE++ +E ++ K ++++EK KKK + KK+ KK+ KK+ S DS
Sbjct: 179 PLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSSPDS 236
Score = 56.2 bits (134), Expect = 5e-08
Identities = 46/178 (25%), Positives = 79/178 (44%), Gaps = 10/178 (5%)
Query: 114 WPSLLDKEREESLRQKRLSE-RERIGELGAPEVWGLSPK---NPEPDSDEHTPVEDEEPK 169
W + ++ ++ K L+E E++ E E+ K E S + + E+ K
Sbjct: 31 WEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKK 90
Query: 170 KSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDE-DN 228
S+S+S SS E K++ K+ K+K++ + S S++E+DS D
Sbjct: 91 SGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKK 150
Query: 229 KRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
K+++K +KEK K SKK K K SS S+ E++E + K+ E
Sbjct: 151 KKKSKDGTEKEKDIKGLSKKRKMYSEDKPL-----SSESLSESEYIEEVRAKKKKSSE 203
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 75.9 bits (185), Expect = 6e-14
Identities = 62/218 (28%), Positives = 107/218 (49%), Gaps = 38/218 (17%)
Query: 167 EPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDE 226
E K + E+ ++K S S+ SKKR++KK K+K +YS S S SDS + SSD
Sbjct: 62 EEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDS 121
Query: 227 DNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
+++ KK K+ KKKK+RS K + ++ +S DS K+ + KD T+ E+
Sbjct: 122 EDE--DKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKS-------KDGTEKEK 172
Query: 287 PSDLIGPEAPKTLTSQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIAS 346
D+ G + + S +DKPL+ E + +EY++ + ++ +SEE
Sbjct: 173 --DIKGLSKKRKMYS-EDKPLS-------SESLSESEYIEEVRAKKKK-----SSEE--- 214
Query: 347 FECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALAS 384
R + E + +K+++ +S +K+ AS
Sbjct: 215 -----------REKATEKTKKKKKHKKHSKKKKKKAAS 241
Score = 70.9 bits (172), Expect = 2e-12
Identities = 51/178 (28%), Positives = 87/178 (48%), Gaps = 27/178 (15%)
Query: 114 WPSLLDKEREESL---------RQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVE 164
W L+K RE+ L RQ++ E+++ G + + DS++ +
Sbjct: 69 WKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQ 128
Query: 165 DEEPKK--------STTSASTSEEEKK---KKSSRSKERSKKRRKKKSSKRKHKKYSEDS 213
+ KK S +S S +E + K KK +SK+ ++K + K +K K YSED
Sbjct: 129 GKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDK 188
Query: 214 --DSDSDSETDSSDEDNKRRAKKAKKKEK-----KKKHRSKKYKKKRSKKSRKESSDS 264
S+S SE++ +E ++ K ++++EK KKK + KK+ KK+ KK+ S DS
Sbjct: 189 PLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSSPDS 246
Score = 56.2 bits (134), Expect = 5e-08
Identities = 46/178 (25%), Positives = 79/178 (44%), Gaps = 10/178 (5%)
Query: 114 WPSLLDKEREESLRQKRLSE-RERIGELGAPEVWGLSPK---NPEPDSDEHTPVEDEEPK 169
W + ++ ++ K L+E E++ E E+ K E S + + E+ K
Sbjct: 41 WEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKK 100
Query: 170 KSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDE-DN 228
S+S+S SS E K++ K+ K+K++ + S S++E+DS D
Sbjct: 101 SGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKK 160
Query: 229 KRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
K+++K +KEK K SKK K K SS S+ E++E + K+ E
Sbjct: 161 KKKSKDGTEKEKDIKGLSKKRKMYSEDKPL-----SSESLSESEYIEEVRAKKKKSSE 213
>gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens]
Length = 293
Score = 74.3 bits (181), Expect = 2e-13
Identities = 59/227 (25%), Positives = 97/227 (42%), Gaps = 24/227 (10%)
Query: 71 SYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKR 130
+YR R S R F S Y+ +P + ++ L+ K
Sbjct: 43 AYRGTKRKMLPSSSSRMRSDGFDEESQRYYW----------RPKNEISGTLEDDFLKAKS 92
Query: 131 LSERERIGELGAPEVWG------LSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKK 184
+++ E P+ WG L P+ E DS + + + + +ST E K K
Sbjct: 93 WNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHK 152
Query: 185 KSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKH 244
KS +S KK++KK+S K++ K E +D +DS ++ S+E +K K+ K+KK
Sbjct: 153 KSKKSH---KKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKK 209
Query: 245 RSKKYKKK-----RSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
KK KK ++ + S DS+S S+E + K + K E
Sbjct: 210 SRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKRE 256
Score = 43.1 bits (100), Expect = 5e-04
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 14/82 (17%)
Query: 220 ETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKK--------------KRSKKSRKESSDSS 265
ETDSSD+ + KK + K H S+K+KK K+ KKS+KE++D +
Sbjct: 122 ETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT 181
Query: 266 SKESQEEFLENPWKDRTKAEEP 287
+ S E E K ++P
Sbjct: 182 ADSSSEFSEETGASGTRKGKQP 203
Score = 35.0 bits (79), Expect = 0.13
Identities = 32/166 (19%), Positives = 65/166 (39%), Gaps = 17/166 (10%)
Query: 57 THQLGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPS 116
TH+ + ++ + + RS +++ S + SSS +S G+
Sbjct: 145 THESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSS----EFSEETGASGTRKG 200
Query: 117 LLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSAS 176
+R++ R+K L + P ++ + N D + +E ++ T
Sbjct: 201 KQPHKRKKKSRKKSLKK---------PALFLEAESNTSHSDDSASSSSEESEERDTKKTK 251
Query: 177 TSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETD 222
+ EKK +S + ++R ++KR + K + D S SE D
Sbjct: 252 RKKREKKAHTSVANNEIQER----TNKRTNWKVATDERSAESSEDD 293
>gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens]
Length = 293
Score = 74.3 bits (181), Expect = 2e-13
Identities = 59/227 (25%), Positives = 97/227 (42%), Gaps = 24/227 (10%)
Query: 71 SYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKR 130
+YR R S R F S Y+ +P + ++ L+ K
Sbjct: 43 AYRGTKRKMLPSSSSRMRSDGFDEESQRYYW----------RPKNEISGTLEDDFLKAKS 92
Query: 131 LSERERIGELGAPEVWG------LSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKK 184
+++ E P+ WG L P+ E DS + + + + +ST E K K
Sbjct: 93 WNKKFYDYEANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHK 152
Query: 185 KSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKH 244
KS +S KK++KK+S K++ K E +D +DS ++ S+E +K K+ K+KK
Sbjct: 153 KSKKSH---KKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKK 209
Query: 245 RSKKYKKK-----RSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
KK KK ++ + S DS+S S+E + K + K E
Sbjct: 210 SRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKRE 256
Score = 43.1 bits (100), Expect = 5e-04
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 14/82 (17%)
Query: 220 ETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKK--------------KRSKKSRKESSDSS 265
ETDSSD+ + KK + K H S+K+KK K+ KKS+KE++D +
Sbjct: 122 ETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT 181
Query: 266 SKESQEEFLENPWKDRTKAEEP 287
+ S E E K ++P
Sbjct: 182 ADSSSEFSEETGASGTRKGKQP 203
Score = 35.0 bits (79), Expect = 0.13
Identities = 32/166 (19%), Positives = 65/166 (39%), Gaps = 17/166 (10%)
Query: 57 THQLGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPS 116
TH+ + ++ + + RS +++ S + SSS +S G+
Sbjct: 145 THESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSS----EFSEETGASGTRKG 200
Query: 117 LLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSAS 176
+R++ R+K L + P ++ + N D + +E ++ T
Sbjct: 201 KQPHKRKKKSRKKSLKK---------PALFLEAESNTSHSDDSASSSSEESEERDTKKTK 251
Query: 177 TSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETD 222
+ EKK +S + ++R ++KR + K + D S SE D
Sbjct: 252 RKKREKKAHTSVANNEIQER----TNKRTNWKVATDERSAESSEDD 293
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 73.9 bits (180), Expect = 2e-13
Identities = 50/176 (28%), Positives = 80/176 (45%), Gaps = 17/176 (9%)
Query: 120 KEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSE 179
KER E ++KR E+ER E G E G K E++E E
Sbjct: 61 KERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKE----------GE 110
Query: 180 EEKKKKSSRSKER------SKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAK 233
E++K+K KER K+R +K+ KR+ +K E + + E + E KR K
Sbjct: 111 EKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERK-ERKKRERK 169
Query: 234 KAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSD 289
+ +KE+++K + +K +KKR + ++ + KE +E E K+ K E D
Sbjct: 170 QVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKD 225
Score = 63.2 bits (152), Expect = 4e-10
Identities = 41/173 (23%), Positives = 83/173 (47%), Gaps = 17/173 (9%)
Query: 114 WPS-LLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKST 172
W S + ++ERE R++ ERE S + E E E E+ +K
Sbjct: 34 WQSEIREREREIETRKEGKKERE-------------SERKKERREREKRKREREKERKRE 80
Query: 173 TSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRA 232
+ E+KK+ +ER K+RR+K++ + + K+ + + T ++ +R+
Sbjct: 81 RGKKEKKGERKKEE---RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE 137
Query: 233 KKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAE 285
++ +++ K+++ + ++ +K+R +K RK+ E +EE E K+R K E
Sbjct: 138 ERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRE 190
Score = 58.2 bits (139), Expect = 1e-08
Identities = 30/108 (27%), Positives = 57/108 (52%), Gaps = 1/108 (0%)
Query: 179 EEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKK 238
E K+ K R ER K+RR+++ KR+ +K + + + + E+ +R+ K+ ++K
Sbjct: 46 ETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK-KRRREK 104
Query: 239 EKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
E K+ +K KKK K+ + S + +E +EE K+R + +E
Sbjct: 105 ENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
Score = 57.0 bits (136), Expect = 3e-08
Identities = 35/131 (26%), Positives = 58/131 (44%), Gaps = 7/131 (5%)
Query: 162 PVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSET 221
P E ++ T +E KK++ S K+ ++R K+K + K +K
Sbjct: 32 PGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERK 91
Query: 222 DSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKS-------RKESSDSSSKESQEEFL 274
E KRR +K K+ ++K+ R KK KK+R + S RKE ++ +E
Sbjct: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
Query: 275 ENPWKDRTKAE 285
E K+R + E
Sbjct: 152 EEREKERERKE 162
>gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens]
Length = 292
Score = 73.6 bits (179), Expect = 3e-13
Identities = 59/227 (25%), Positives = 98/227 (43%), Gaps = 25/227 (11%)
Query: 71 SYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKR 130
+YR R S R F S Y+ +P + ++ L+ K
Sbjct: 43 AYRGTKRKMLPSSSSRMRSDGFDEESQRYYW----------RPKNEISGTLEDDFLKAKS 92
Query: 131 LSERERIGELGAPEVWG------LSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKK 184
+++ E P+ WG L P+ E DSD+ +D K T+ S + +
Sbjct: 93 WNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQ----QDITNGKKTSPQVKSSTHESR 148
Query: 185 KSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKH 244
K +SK+ KK++KK+S K++ K E +D +DS ++ S+E +K K+ K+KK
Sbjct: 149 KHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKK 208
Query: 245 RSKKYKKK-----RSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
KK KK ++ + S DS+S S+E + K + K E
Sbjct: 209 SRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKRE 255
Score = 44.3 bits (103), Expect = 2e-04
Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 7/86 (8%)
Query: 209 YSEDSDSDSDSE-------TDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKES 261
Y E+ ++DSD + T + + ++K KK +K K + KK K+ KKS+KE+
Sbjct: 117 YPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEA 176
Query: 262 SDSSSKESQEEFLENPWKDRTKAEEP 287
+D ++ S E E K ++P
Sbjct: 177 TDITADSSSEFSEETGASGTRKGKQP 202
Score = 35.0 bits (79), Expect = 0.13
Identities = 32/166 (19%), Positives = 65/166 (39%), Gaps = 17/166 (10%)
Query: 57 THQLGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPS 116
TH+ + ++ + + RS +++ S + SSS +S G+
Sbjct: 144 THESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSS----EFSEETGASGTRKG 199
Query: 117 LLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSAS 176
+R++ R+K L + P ++ + N D + +E ++ T
Sbjct: 200 KQPHKRKKKSRKKSLKK---------PALFLEAESNTSHSDDSASSSSEESEERDTKKTK 250
Query: 177 TSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETD 222
+ EKK +S + ++R ++KR + K + D S SE D
Sbjct: 251 RKKREKKAHTSVANNEIQER----TNKRTNWKVATDERSAESSEDD 292
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 72.8 bits (177), Expect = 5e-13
Identities = 46/166 (27%), Positives = 84/166 (50%), Gaps = 12/166 (7%)
Query: 120 KEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSE 179
KER E ++KR E+ER E G K + + ++ E K+ E
Sbjct: 38 KERREREKRKREREKERKRERG---------KKEKKKRKKRERGKERERKRKEREKQRKE 88
Query: 180 EEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKE 239
+K++ R KE+ K+ RK++ +R+ KK E + + +++ + KRR KK +K+
Sbjct: 89 RREKERRKRKKEKKKRERKQR-GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKER 147
Query: 240 KKKKHRSK--KYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTK 283
K++K R K + +KKR K+ R++ + + KE ++E ++R K
Sbjct: 148 KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKK 193
Score = 62.4 bits (150), Expect = 7e-10
Identities = 29/120 (24%), Positives = 65/120 (54%), Gaps = 3/120 (2%)
Query: 169 KKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDN 228
K T S ++E++++ R +ER K+R++++ K K K+ + + + + ++
Sbjct: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
Query: 229 KRRAKK---AKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAE 285
K R +K +KKEKKK+ R ++ +++R KK ++ + +K+ +E + K + + E
Sbjct: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
Score = 62.4 bits (150), Expect = 7e-10
Identities = 32/148 (21%), Positives = 74/148 (50%), Gaps = 9/148 (6%)
Query: 120 KEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSE 179
KERE+ +++R ER + + K E + ++ +K +
Sbjct: 80 KEREKQRKERREKERRKRKK---------EKKKRERKQRGRRERKKKKERKERERENKQR 130
Query: 180 EEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKE 239
E+K+K R K+R K+R+++K ++ +K + + + + + + ++ K+ ++ +++E
Sbjct: 131 RERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRE 190
Query: 240 KKKKHRSKKYKKKRSKKSRKESSDSSSK 267
+KK+ + ++ KKK KK RK + S+
Sbjct: 191 RKKERKKERRKKKERKKDRKTDRQTDSQ 218
Score = 60.8 bits (146), Expect = 2e-09
Identities = 36/136 (26%), Positives = 63/136 (46%), Gaps = 15/136 (11%)
Query: 166 EEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSD 225
E K+ E++K+KK R KER +KR++++ +++ ++ + +
Sbjct: 49 EREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQ 108
Query: 226 EDNKRRAKKAKKKEKK---KKHRSKKYKKKRSKKSRKE------------SSDSSSKESQ 270
+ R KK ++KE++ K+ R +K KK+R KK RKE KE +
Sbjct: 109 RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEER 168
Query: 271 EEFLENPWKDRTKAEE 286
E+ E K+R K E
Sbjct: 169 EKKRERNRKERKKERE 184
Score = 58.9 bits (141), Expect = 8e-09
Identities = 25/125 (20%), Positives = 63/125 (50%)
Query: 162 PVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSET 221
P E ++ + +++++ R +ER KK +KK+ + + K+
Sbjct: 28 PCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK 87
Query: 222 DSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDR 281
+ +++ ++R K+ KK+E+K++ R ++ KKK K+ +E+ ++ ++ + K+R
Sbjct: 88 ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKER 147
Query: 282 TKAEE 286
+ +E
Sbjct: 148 KREKE 152
Score = 57.8 bits (138), Expect = 2e-08
Identities = 31/137 (22%), Positives = 66/137 (48%), Gaps = 11/137 (8%)
Query: 154 EPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDS 213
+P + + + E ++ +E K+++ + K++ KKR + K +RK K+ +
Sbjct: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
Query: 214 DSDSDSE-----TDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKE 268
+ E + + K+R ++ +KK+K++K R ++ K++R +K +K KE
Sbjct: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
Query: 269 SQEEFLENPWKDRTKAE 285
+ E K+R K E
Sbjct: 147 RKRE------KERGKRE 157
Score = 56.6 bits (135), Expect = 4e-08
Identities = 31/152 (20%), Positives = 73/152 (48%), Gaps = 13/152 (8%)
Query: 120 KEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSE 179
KER E R+KR E+++ + + E +E ++ +
Sbjct: 87 KERREKERRKRKKEKKK------------RERKQRGRRERKKKKERKERERENKQRRERK 134
Query: 180 EEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKE 239
+K++K R KER +++ + K +++ K+ E+ + + ++ +R+ ++ +KKE
Sbjct: 135 RKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
Query: 240 KKKKHRSKKYKKKRSKKSRKESSDSSSKESQE 271
+KK R KK ++K+ +K+ +++ + +E
Sbjct: 195 RKK-ERRKKKERKKDRKTDRQTDSQVFRPLRE 225
Score = 52.4 bits (124), Expect = 8e-07
Identities = 29/144 (20%), Positives = 70/144 (48%), Gaps = 7/144 (4%)
Query: 119 DKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTS 178
+KER + ++K+ ER++ G + K + + E +K
Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKK------KKERKERERENKQRRERKRKKRRKKKRR 144
Query: 179 EEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKK 238
+E K++K +ER +K+RKK+ ++K ++ ++ + + + + + +R+ ++ KKK
Sbjct: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERK-ERRERKKERKKERRKKK 203
Query: 239 EKKKKHRSKKYKKKRSKKSRKESS 262
E+KK ++ + + + +ES+
Sbjct: 204 ERKKDRKTDRQTDSQVFRPLRESA 227
Score = 45.4 bits (106), Expect = 9e-05
Identities = 25/97 (25%), Positives = 51/97 (52%)
Query: 190 KERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKY 249
K S + K +++ + S S + E++ E +R +K ++++++K+ R KK
Sbjct: 3 KAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKE 62
Query: 250 KKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
KKKR K+ R + + KE +++ E K+R K ++
Sbjct: 63 KKKRKKRERGKERERKRKEREKQRKERREKERRKRKK 99
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 72.4 bits (176), Expect = 7e-13
Identities = 43/100 (43%), Positives = 57/100 (57%), Gaps = 4/100 (4%)
Query: 187 SRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRS 246
S+ K+ KKR K SS S DSDS SDS++ SSD + A + K K++KKKHR
Sbjct: 181 SKVKKEEKKRHKSSSSSSSS---SSDSDSSSDSQS-SSDSSDSESATEEKSKKRKKKHRK 236
Query: 247 KKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
K K+ KK RK+S S+S ES+ E LE + + EE
Sbjct: 237 NSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEE 276
Score = 65.1 bits (157), Expect = 1e-10
Identities = 61/271 (22%), Positives = 108/271 (39%), Gaps = 21/271 (7%)
Query: 26 KSPKPSKSARSPRGRRSRSHSCS------RSGDRNGLTHQLGGLSQGSRNQSYRSRSRSR 79
KSP + R R C+ S R L + G +G + YR+ SRSR
Sbjct: 289 KSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSR 348
Query: 80 SRER----PSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKRLSERE 135
SR+R + P + + S R DK S L++ +E R+ ER+
Sbjct: 349 SRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDK---SELNEIKENQRSPVRVKERK 405
Query: 136 RIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKK 195
E +P +++ V+D + + E+ K ++ K+R+K
Sbjct: 406 ITDHRNVSE-------SPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKS 458
Query: 196 RRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSK 255
+ + KS K K K DS + + E R + K+KEK+ + K ++ RSK
Sbjct: 459 KSRSKS-KEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSK 517
Query: 256 KSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
+ K+ S++ + E + ++++ E
Sbjct: 518 EKSKQLESKSNEHDHSKSKEKDRRAQSRSRE 548
Score = 64.3 bits (155), Expect = 2e-10
Identities = 65/284 (22%), Positives = 112/284 (39%), Gaps = 38/284 (13%)
Query: 5 SGSRSPDREASGSGGRRR---SSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLG 61
S S+ D+E S S + + S S SKS R +SRS C
Sbjct: 504 SDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECD------------- 550
Query: 62 GLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKE 121
+++G + + R+R RSRSR+R R SR + D+ +
Sbjct: 551 -ITKGKHSYNSRTRERSRSRDRSRRVR----------------SRTHDRDRSRSKEYHRY 593
Query: 122 REESLRQK-RLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEE 180
RE+ R++ R RER G + + S E E + K S+
Sbjct: 594 REQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSERE--ESQSRNKDKYRNQESKS 651
Query: 181 EKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEK 240
+K++S S++R + + +S ++ D D S+ S +DN+ ++ K KE
Sbjct: 652 SHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKED 711
Query: 241 KKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKA 284
+K S + + ++SK + +K+ E +P D K+
Sbjct: 712 EKIRSSVEKENQKSKGQENDHVHEKNKKFDHE--SSPGTDEDKS 753
Score = 51.6 bits (122), Expect = 1e-06
Identities = 62/275 (22%), Positives = 113/275 (41%), Gaps = 60/275 (21%)
Query: 21 RRSSSKSPKPSKSA--RSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQGSRNQSYRSRSRS 78
RR+S K K R+ RS+S S+S +R+ S+ +RN+ R RSRS
Sbjct: 439 RRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERD---------SKHNRNEEKRMRSRS 489
Query: 79 RSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKRLSERERIG 138
+ R+ + +KE++ + K ER R
Sbjct: 490 KGRDHENVK-------------------------------EKEKQSDSKGKD-QERSRSK 517
Query: 139 ELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRK 198
E K E S+EH + +E + S S + K K S + R+++R +
Sbjct: 518 E---------KSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYN-SRTRERSR 567
Query: 199 KKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKK---KHRSKKYKKKR-- 253
+ R+ + + D D E E RR +++ +E++ + RSK +++R
Sbjct: 568 SRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRD 627
Query: 254 SKKSRKESSDSSSKES--QEEFLENPWKDRTKAEE 286
S+ S +E S S +K+ +E + K+ +++E+
Sbjct: 628 SRSSEREESQSRNKDKYRNQESKSSHRKENSESEK 662
Score = 50.4 bits (119), Expect = 3e-06
Identities = 57/282 (20%), Positives = 113/282 (40%), Gaps = 36/282 (12%)
Query: 12 REASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQGSRNQS 71
++ + S R +S KS + ++ R R S S+ D + + ++Q
Sbjct: 453 KKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQE 512
Query: 72 YRSRSRSRSRERPSAPRGIPFASASSSVYYG-SYSRPYGSDKPWPSLLDKEREESLRQKR 130
RSRS+ +S++ S + + S SR K S + RE S R
Sbjct: 513 -RSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERS----R 567
Query: 131 LSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSK 190
+R R V + S E+ ++E ++ S S E++ RS+
Sbjct: 568 SRDRSR-------RVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRS---RERRTPPGRSR 617
Query: 191 ERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHR--SKK 248
+ ++RR++ DS + +E R K + +E K HR + +
Sbjct: 618 SKDRRRRRR------------------DSRSSEREESQSRNKDKYRNQESKSSHRKENSE 659
Query: 249 YKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSDL 290
+K+ KSR +S ++S+E + + ++P+ ++ + ++L
Sbjct: 660 SEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNEL 701
Score = 44.7 bits (104), Expect = 2e-04
Identities = 30/125 (24%), Positives = 60/125 (48%), Gaps = 5/125 (4%)
Query: 149 SPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKK 208
S + SD + + + S+ S S +EE+ KK+ + ++ S+K KK+ KRK K
Sbjct: 194 SSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKH-KKEKKKRKKSK 252
Query: 209 YSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKK---KKHRSKKYKKKRSKKSRKESSDSS 265
S S+S++++ ++ + R + E + +K K +K+R + R+ + +
Sbjct: 253 KSASSESEAEN-LEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECN 311
Query: 266 SKESQ 270
SQ
Sbjct: 312 PPNSQ 316
Score = 38.1 bits (87), Expect = 0.015
Identities = 23/120 (19%), Positives = 54/120 (45%), Gaps = 2/120 (1%)
Query: 149 SPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRS--KERSKKRRKKKSSKRKH 206
S + + SD + + + + +T S ++K +K+SR KE+ K+++ KKS+ +
Sbjct: 200 SSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSES 259
Query: 207 KKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSS 266
+ + ++ S + + R K K + K +++R ++ +S +S
Sbjct: 260 EAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPAS 319
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 72.0 bits (175), Expect = 9e-13
Identities = 77/319 (24%), Positives = 126/319 (39%), Gaps = 42/319 (13%)
Query: 5 SGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLS 64
SGS S D E S +++ S K K A + ++ S S + +T
Sbjct: 1113 SGSSSSDAEESSEDNKKKKQRTSSK--KKAVIVKEKKRNSLRTSTKRKQADITSSSSSDI 1170
Query: 65 QGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREE 124
+ S S + +P + SS + S K P +D + ++
Sbjct: 1171 EDDDQNSIGEGSSDEQKIKPVTENLV----LSSHTGFCQSSGDEALSKSVPVTVDDDDDD 1226
Query: 125 SLRQKRLSERERIGELGA---PEVWGLSPKNPEPDS------DEHTPVEDEEPKKSTTSA 175
+ + R++++ + E+ A + G S PE +E P DEE K S
Sbjct: 1227 NDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENP-GDEEAKNQVNSE 1285
Query: 176 STSEEEKKKK------------------SSRSKERSKKRRKKKSSKRKHKKYSEDSDSDS 217
S S+ E+ KK S K+ K K+ + + K SEDS+ DS
Sbjct: 1286 SDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE-DS 1344
Query: 218 D-------SETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQ 270
D E S+++ + R + AKK E ++ RS K KKKR + +E S S +K +
Sbjct: 1345 DFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNS 1404
Query: 271 EEFLENPWKDRTKAEEPSD 289
EE E ++ + EE +
Sbjct: 1405 EEEEEEKEEEEEEEEEEEE 1423
Score = 66.6 bits (161), Expect = 4e-11
Identities = 55/182 (30%), Positives = 84/182 (46%), Gaps = 20/182 (10%)
Query: 119 DKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPK--------K 170
D E EE ++ E G+ A + N E DSD E ++P+ K
Sbjct: 1255 DDEPEEGKKRTGKQNEENPGDEEAK-----NQVNSESDSDSE---ESKKPRYRHRLLRHK 1306
Query: 171 STTSASTSEEEKKKKSSRSKE-RSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNK 229
T S S EEKK K KE + + RRK S + + E S+ SE++
Sbjct: 1307 LTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRT 1366
Query: 230 RRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSD--SSSKESQEEFLENPWKDRTKAEEP 287
R AKKA+ +E ++ ++ KK K++R K SS+ S+S+E +EE E ++ + EE
Sbjct: 1367 RSAKKAELEENQRSYKQKK-KRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEE 1425
Query: 288 SD 289
D
Sbjct: 1426 ED 1427
Score = 51.2 bits (121), Expect = 2e-06
Identities = 66/284 (23%), Positives = 118/284 (41%), Gaps = 38/284 (13%)
Query: 163 VEDEEPKKSTTSASTSEEEK---KKKSSRSKE-RSKKRRKKKSSKRKHKKYSEDSDSDSD 218
+ D PKK SAST +K K++S S E R K+KS K K + D SD
Sbjct: 866 LRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSD 925
Query: 219 --------SETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSK-ES 269
++D + ED+K+++KK E+KKK K K + ++ + SSD + K
Sbjct: 926 IAEKFLKKDQSDETSEDDKKQSKKG--TEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPE 983
Query: 270 QEEFLENP------WKDRTKAEEPSDLIGPEAPK---TLTSQDDKPLNYGHALLPGEG-- 318
+EE P T E+ S I + K L+ +K G + E
Sbjct: 984 REEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKK 1043
Query: 319 AAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMS----GSRHRRMEAVRLRKENQIY 374
+ Y + KR G+ ++ +S + Y M S +R++ + LR+ +
Sbjct: 1044 SKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLS 1103
Query: 375 SADEKRAL--------ASFNQEERRKRENKILASFREMVYRKTK 410
S + + A + E+ +K++ + + + ++ ++ K
Sbjct: 1104 SKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKK 1147
Score = 47.8 bits (112), Expect = 2e-05
Identities = 28/107 (26%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
Query: 166 EEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSD 225
++ S T + +E+ S + +R + R ++ S +++ K + S SD+E S
Sbjct: 1067 QDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAE--ESS 1124
Query: 226 EDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEE 272
EDNK++ ++ K+K + KK R+ RK++ +SS S E
Sbjct: 1125 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIE 1171
Score = 47.0 bits (110), Expect = 3e-05
Identities = 32/141 (22%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Query: 151 KNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKE---RSKKRRKKKSSKRKHK 207
+N S E + D + + S SE+E++ ++ +K+ +R K+ KR+
Sbjct: 1331 RNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRI 1390
Query: 208 KYSEDSDSD--SDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSS 265
K EDS S+ S+SE + +++ + ++ +++E++ ++ K K KK RK D
Sbjct: 1391 KVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDK 1450
Query: 266 SKESQEEFLENPWKDRTKAEE 286
+ + L+ + R + E
Sbjct: 1451 LRTETQNALKEEEERRKRIAE 1471
Score = 45.1 bits (105), Expect = 1e-04
Identities = 30/157 (19%), Positives = 70/157 (44%), Gaps = 10/157 (6%)
Query: 157 SDEHTPVEDEEPKKSTTSASTSEEE--------KKKKSSRSKERSKKRRKKKSSKRKHKK 208
S+E + EDE+ ++ ++ EE KK++ + +E S K S + + +K
Sbjct: 1352 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK 1411
Query: 209 YSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKE 268
E+ + + + E + + D+ + K +KK +K K + ++ + KE + +
Sbjct: 1412 EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDK--LRTETQNALKEEEERRKRI 1469
Query: 269 SQEEFLENPWKDRTKAEEPSDLIGPEAPKTLTSQDDK 305
++ E ++ + E+ S P K + +D++
Sbjct: 1470 AEREREREKLREVIEIEDASPTKCPITTKLVLDEDEE 1506
Score = 43.9 bits (102), Expect = 3e-04
Identities = 41/165 (24%), Positives = 64/165 (38%), Gaps = 4/165 (2%)
Query: 111 DKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKK 170
D P P+ L K ++ + E + L S + ++ HT + K
Sbjct: 671 DNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLK 730
Query: 171 STTSASTSEEEKKKKS-SRSKERSKKRRKKKS---SKRKHKKYSEDSDSDSDSETDSSDE 226
+ + K+K S S S +KK + KS SK+K + SE S+ DS+ E +
Sbjct: 731 TQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSM 790
Query: 227 DNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQE 271
A+ KK+ K +K SKK + K SQE
Sbjct: 791 SKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQE 835
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/161 (27%), Positives = 73/161 (45%), Gaps = 23/161 (14%)
Query: 150 PKNPEPDSDEHTPVEDEEPKK---STTSASTSEEEKKKKSSRSKERSKKRRKKKSSKR-- 204
P + D D++ P E+ KK A+ S +E S E KKR K++ +
Sbjct: 1217 PVTVDDDDDDNDP-ENRIAKKMLLEEIKANLSSDEDGS-SDDEPEEGKKRTGKQNEENPG 1274
Query: 205 -KHKKYSEDSDSDSDSETDSSDEDNKRRAKK----------AKKKEKKKKHRSKKYKKKR 253
+ K +S+SDSDSE R + +KK K K+H+ K + +R
Sbjct: 1275 DEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRR 1334
Query: 254 SKKSRKESSDSSSKES--QEEF--LENPWKDRTKAEEPSDL 290
K S ++S DS +ES EE E+ + RT++ + ++L
Sbjct: 1335 -KVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL 1374
Score = 40.8 bits (94), Expect = 0.002
Identities = 48/226 (21%), Positives = 97/226 (42%), Gaps = 25/226 (11%)
Query: 20 RRRSSSKSPKPSKSARSPRGR-RSRSHSCSRSGDRNGLTHQLGGLSQGSRNQSYRSRSRS 78
+ + +S+S S+ ++ PR R R H + S +G + ++ ++ + R+R
Sbjct: 1279 KNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKK----TKPKEHKEVKGRNRR 1334
Query: 79 RSRERPSAPRGIPFASASSSVYYGS-YSRPYGSDKPWPSLLDKEREESLRQKRLSERERI 137
+ S + S V RP L +E + S +QK+ R ++
Sbjct: 1335 KVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL--EENQRSYKQKKKRRRIKV 1392
Query: 138 GELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRR 197
E + E + N E + +E E+EE ++ EEE++ ++ SK K R+
Sbjct: 1393 QEDSSSE----NKSNSEEEEEEKEEEEEEEEEE--------EEEEEDENDDSKSPGKGRK 1440
Query: 198 KKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKK 243
K + + K +E ++ + E E KR A++ +++EK ++
Sbjct: 1441 KIRKILKDDKLRTETQNALKEEE-----ERRKRIAEREREREKLRE 1481
Score = 39.3 bits (90), Expect = 0.007
Identities = 88/459 (19%), Positives = 154/459 (33%), Gaps = 75/459 (16%)
Query: 5 SGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLS 64
S S D + G S K + + S S + +R + H G+
Sbjct: 936 SDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIK 995
Query: 65 QGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYG----------SYSRPYGSDKPW 114
Q + + + R++ S + A S G S + YG +K
Sbjct: 996 QIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKR 1055
Query: 115 PSLLDKEREE-----SLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPK 169
LL K + S ++ S +E + + + S + E +
Sbjct: 1056 CKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGS 1115
Query: 170 KSTTSASTSEEEKKKK---SSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDE 226
S+ + +SE+ KKKK SS+ K K +K+ S + K+ D S S S+ + D+
Sbjct: 1116 SSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQ 1175
Query: 227 DNKRRAKKAKKKEK---------------------------------------KKKHRSK 247
++ ++K K + +K
Sbjct: 1176 NSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAK 1235
Query: 248 KYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTK---AEEPSDLIGPEAPKTLTSQDD 304
K + K + D SS + EE + K + EE + + E+ S++
Sbjct: 1236 KMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDS--DSEES 1293
Query: 305 KPLNYGHALL-------PGE-GAAMAEYVKAGKRIPRRGEIGLTSE--EIASFECSGYVM 354
K Y H LL GE G K K + R ++SE E + F+ SG
Sbjct: 1294 KKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSE 1353
Query: 355 SGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKR 393
S + R R + + +R S+ Q+++R+R
Sbjct: 1354 EVSESEDEQRPRTRSAKKAELEENQR---SYKQKKKRRR 1389
Score = 34.7 bits (78), Expect = 0.16
Identities = 54/266 (20%), Positives = 93/266 (34%), Gaps = 45/266 (16%)
Query: 165 DEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKK--------KSSKRKHKKYSEDSDSD 216
+ P S + +E K+K+ R K +R K +K K SE D +
Sbjct: 631 ETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQN 690
Query: 217 SDSE--------------TDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESS 262
SDS+ + SSD D K K K K KR +KS S
Sbjct: 691 SDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGS 750
Query: 263 DSSSKESQEEFLENPWKDRTKAEEPSDLIGPEAPKTLTSQDDKPLNYGHALLPGEGAAMA 322
D +K+ + K + + + S E K + S + GAA
Sbjct: 751 DFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKS------------MSKIGAART 798
Query: 323 EYVKAGKRIPRRGEIGLTSEEIASFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRAL 382
KRIP +++ S E + G ++ + ++ +E A+ K+
Sbjct: 799 ----TKKRIP-------NTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQER 847
Query: 383 ASFNQEERRKRENKILASFREMVYRK 408
+F+ E ++ + R+ + +K
Sbjct: 848 ETFSSAEGTVDKDTTIMELRDRLPKK 873
Score = 31.2 bits (69), Expect = 1.8
Identities = 20/70 (28%), Positives = 30/70 (42%), Gaps = 9/70 (12%)
Query: 214 DSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEF 273
D DS E +SD D + + KKKK + KK +K+SS S S +
Sbjct: 1865 DEDSMDEFIASDSDETSMSLSSDDYTKKKK---------KGKKGKKDSSSSGSGSDNDVE 1915
Query: 274 LENPWKDRTK 283
+ W R++
Sbjct: 1916 VIKVWNSRSR 1925
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 72.0 bits (175), Expect = 9e-13
Identities = 77/319 (24%), Positives = 126/319 (39%), Gaps = 42/319 (13%)
Query: 5 SGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLS 64
SGS S D E S +++ S K K A + ++ S S + +T
Sbjct: 1151 SGSSSSDAEESSEDNKKKKQRTSSK--KKAVIVKEKKRNSLRTSTKRKQADITSSSSSDI 1208
Query: 65 QGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREE 124
+ S S + +P + SS + S K P +D + ++
Sbjct: 1209 EDDDQNSIGEGSSDEQKIKPVTENLV----LSSHTGFCQSSGDEALSKSVPVTVDDDDDD 1264
Query: 125 SLRQKRLSERERIGELGA---PEVWGLSPKNPEPDS------DEHTPVEDEEPKKSTTSA 175
+ + R++++ + E+ A + G S PE +E P DEE K S
Sbjct: 1265 NDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENP-GDEEAKNQVNSE 1323
Query: 176 STSEEEKKKK------------------SSRSKERSKKRRKKKSSKRKHKKYSEDSDSDS 217
S S+ E+ KK S K+ K K+ + + K SEDS+ DS
Sbjct: 1324 SDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE-DS 1382
Query: 218 D-------SETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQ 270
D E S+++ + R + AKK E ++ RS K KKKR + +E S S +K +
Sbjct: 1383 DFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNS 1442
Query: 271 EEFLENPWKDRTKAEEPSD 289
EE E ++ + EE +
Sbjct: 1443 EEEEEEKEEEEEEEEEEEE 1461
Score = 66.6 bits (161), Expect = 4e-11
Identities = 55/182 (30%), Positives = 84/182 (46%), Gaps = 20/182 (10%)
Query: 119 DKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPK--------K 170
D E EE ++ E G+ A + N E DSD E ++P+ K
Sbjct: 1293 DDEPEEGKKRTGKQNEENPGDEEAK-----NQVNSESDSDSE---ESKKPRYRHRLLRHK 1344
Query: 171 STTSASTSEEEKKKKSSRSKE-RSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNK 229
T S S EEKK K KE + + RRK S + + E S+ SE++
Sbjct: 1345 LTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRT 1404
Query: 230 RRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSD--SSSKESQEEFLENPWKDRTKAEEP 287
R AKKA+ +E ++ ++ KK K++R K SS+ S+S+E +EE E ++ + EE
Sbjct: 1405 RSAKKAELEENQRSYKQKK-KRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEE 1463
Query: 288 SD 289
D
Sbjct: 1464 ED 1465
Score = 51.2 bits (121), Expect = 2e-06
Identities = 66/284 (23%), Positives = 118/284 (41%), Gaps = 38/284 (13%)
Query: 163 VEDEEPKKSTTSASTSEEEK---KKKSSRSKE-RSKKRRKKKSSKRKHKKYSEDSDSDSD 218
+ D PKK SAST +K K++S S E R K+KS K K + D SD
Sbjct: 904 LRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSD 963
Query: 219 --------SETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSK-ES 269
++D + ED+K+++KK E+KKK K K + ++ + SSD + K
Sbjct: 964 IAEKFLKKDQSDETSEDDKKQSKKG--TEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPE 1021
Query: 270 QEEFLENP------WKDRTKAEEPSDLIGPEAPK---TLTSQDDKPLNYGHALLPGEG-- 318
+EE P T E+ S I + K L+ +K G + E
Sbjct: 1022 REEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKK 1081
Query: 319 AAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMS----GSRHRRMEAVRLRKENQIY 374
+ Y + KR G+ ++ +S + Y M S +R++ + LR+ +
Sbjct: 1082 SKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLS 1141
Query: 375 SADEKRAL--------ASFNQEERRKRENKILASFREMVYRKTK 410
S + + A + E+ +K++ + + + ++ ++ K
Sbjct: 1142 SKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKK 1185
Score = 47.8 bits (112), Expect = 2e-05
Identities = 28/107 (26%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
Query: 166 EEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSD 225
++ S T + +E+ S + +R + R ++ S +++ K + S SD+E S
Sbjct: 1105 QDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAE--ESS 1162
Query: 226 EDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEE 272
EDNK++ ++ K+K + KK R+ RK++ +SS S E
Sbjct: 1163 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIE 1209
Score = 47.0 bits (110), Expect = 3e-05
Identities = 32/141 (22%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Query: 151 KNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKE---RSKKRRKKKSSKRKHK 207
+N S E + D + + S SE+E++ ++ +K+ +R K+ KR+
Sbjct: 1369 RNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRI 1428
Query: 208 KYSEDSDSD--SDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSS 265
K EDS S+ S+SE + +++ + ++ +++E++ ++ K K KK RK D
Sbjct: 1429 KVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDK 1488
Query: 266 SKESQEEFLENPWKDRTKAEE 286
+ + L+ + R + E
Sbjct: 1489 LRTETQNALKEEEERRKRIAE 1509
Score = 45.1 bits (105), Expect = 1e-04
Identities = 30/157 (19%), Positives = 70/157 (44%), Gaps = 10/157 (6%)
Query: 157 SDEHTPVEDEEPKKSTTSASTSEEE--------KKKKSSRSKERSKKRRKKKSSKRKHKK 208
S+E + EDE+ ++ ++ EE KK++ + +E S K S + + +K
Sbjct: 1390 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK 1449
Query: 209 YSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKE 268
E+ + + + E + + D+ + K +KK +K K + ++ + KE + +
Sbjct: 1450 EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDK--LRTETQNALKEEEERRKRI 1507
Query: 269 SQEEFLENPWKDRTKAEEPSDLIGPEAPKTLTSQDDK 305
++ E ++ + E+ S P K + +D++
Sbjct: 1508 AEREREREKLREVIEIEDASPTKCPITTKLVLDEDEE 1544
Score = 43.9 bits (102), Expect = 3e-04
Identities = 41/165 (24%), Positives = 64/165 (38%), Gaps = 4/165 (2%)
Query: 111 DKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKK 170
D P P+ L K ++ + E + L S + ++ HT + K
Sbjct: 709 DNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLK 768
Query: 171 STTSASTSEEEKKKKS-SRSKERSKKRRKKKS---SKRKHKKYSEDSDSDSDSETDSSDE 226
+ + K+K S S S +KK + KS SK+K + SE S+ DS+ E +
Sbjct: 769 TQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSM 828
Query: 227 DNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQE 271
A+ KK+ K +K SKK + K SQE
Sbjct: 829 SKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQE 873
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/161 (27%), Positives = 73/161 (45%), Gaps = 23/161 (14%)
Query: 150 PKNPEPDSDEHTPVEDEEPKK---STTSASTSEEEKKKKSSRSKERSKKRRKKKSSKR-- 204
P + D D++ P E+ KK A+ S +E S E KKR K++ +
Sbjct: 1255 PVTVDDDDDDNDP-ENRIAKKMLLEEIKANLSSDEDGS-SDDEPEEGKKRTGKQNEENPG 1312
Query: 205 -KHKKYSEDSDSDSDSETDSSDEDNKRRAKK----------AKKKEKKKKHRSKKYKKKR 253
+ K +S+SDSDSE R + +KK K K+H+ K + +R
Sbjct: 1313 DEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRR 1372
Query: 254 SKKSRKESSDSSSKES--QEEF--LENPWKDRTKAEEPSDL 290
K S ++S DS +ES EE E+ + RT++ + ++L
Sbjct: 1373 -KVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL 1412
Score = 40.8 bits (94), Expect = 0.002
Identities = 48/226 (21%), Positives = 97/226 (42%), Gaps = 25/226 (11%)
Query: 20 RRRSSSKSPKPSKSARSPRGR-RSRSHSCSRSGDRNGLTHQLGGLSQGSRNQSYRSRSRS 78
+ + +S+S S+ ++ PR R R H + S +G + ++ ++ + R+R
Sbjct: 1317 KNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKK----TKPKEHKEVKGRNRR 1372
Query: 79 RSRERPSAPRGIPFASASSSVYYGS-YSRPYGSDKPWPSLLDKEREESLRQKRLSERERI 137
+ S + S V RP L +E + S +QK+ R ++
Sbjct: 1373 KVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL--EENQRSYKQKKKRRRIKV 1430
Query: 138 GELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRR 197
E + E + N E + +E E+EE ++ EEE++ ++ SK K R+
Sbjct: 1431 QEDSSSE----NKSNSEEEEEEKEEEEEEEEEE--------EEEEEDENDDSKSPGKGRK 1478
Query: 198 KKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKK 243
K + + K +E ++ + E E KR A++ +++EK ++
Sbjct: 1479 KIRKILKDDKLRTETQNALKEEE-----ERRKRIAEREREREKLRE 1519
Score = 39.3 bits (90), Expect = 0.007
Identities = 88/459 (19%), Positives = 154/459 (33%), Gaps = 75/459 (16%)
Query: 5 SGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLS 64
S S D + G S K + + S S + +R + H G+
Sbjct: 974 SDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIK 1033
Query: 65 QGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYG----------SYSRPYGSDKPW 114
Q + + + R++ S + A S G S + YG +K
Sbjct: 1034 QIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKR 1093
Query: 115 PSLLDKEREE-----SLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPK 169
LL K + S ++ S +E + + + S + E +
Sbjct: 1094 CKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGS 1153
Query: 170 KSTTSASTSEEEKKKK---SSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDE 226
S+ + +SE+ KKKK SS+ K K +K+ S + K+ D S S S+ + D+
Sbjct: 1154 SSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQ 1213
Query: 227 DNKRRAKKAKKKEK---------------------------------------KKKHRSK 247
++ ++K K + +K
Sbjct: 1214 NSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAK 1273
Query: 248 KYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTK---AEEPSDLIGPEAPKTLTSQDD 304
K + K + D SS + EE + K + EE + + E+ S++
Sbjct: 1274 KMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDS--DSEES 1331
Query: 305 KPLNYGHALL-------PGE-GAAMAEYVKAGKRIPRRGEIGLTSE--EIASFECSGYVM 354
K Y H LL GE G K K + R ++SE E + F+ SG
Sbjct: 1332 KKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSE 1391
Query: 355 SGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKR 393
S + R R + + +R S+ Q+++R+R
Sbjct: 1392 EVSESEDEQRPRTRSAKKAELEENQR---SYKQKKKRRR 1427
Score = 34.7 bits (78), Expect = 0.16
Identities = 54/266 (20%), Positives = 93/266 (34%), Gaps = 45/266 (16%)
Query: 165 DEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKK--------KSSKRKHKKYSEDSDSD 216
+ P S + +E K+K+ R K +R K +K K SE D +
Sbjct: 669 ETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQN 728
Query: 217 SDSE--------------TDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESS 262
SDS+ + SSD D K K K K KR +KS S
Sbjct: 729 SDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGS 788
Query: 263 DSSSKESQEEFLENPWKDRTKAEEPSDLIGPEAPKTLTSQDDKPLNYGHALLPGEGAAMA 322
D +K+ + K + + + S E K + S + GAA
Sbjct: 789 DFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKS------------MSKIGAART 836
Query: 323 EYVKAGKRIPRRGEIGLTSEEIASFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRAL 382
KRIP +++ S E + G ++ + ++ +E A+ K+
Sbjct: 837 ----TKKRIP-------NTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQER 885
Query: 383 ASFNQEERRKRENKILASFREMVYRK 408
+F+ E ++ + R+ + +K
Sbjct: 886 ETFSSAEGTVDKDTTIMELRDRLPKK 911
Score = 31.2 bits (69), Expect = 1.8
Identities = 20/70 (28%), Positives = 30/70 (42%), Gaps = 9/70 (12%)
Query: 214 DSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEF 273
D DS E +SD D + + KKKK + KK +K+SS S S +
Sbjct: 1903 DEDSMDEFIASDSDETSMSLSSDDYTKKKK---------KGKKGKKDSSSSGSGSDNDVE 1953
Query: 274 LENPWKDRTK 283
+ W R++
Sbjct: 1954 VIKVWNSRSR 1963
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 71.6 bits (174), Expect = 1e-12
Identities = 74/276 (26%), Positives = 114/276 (41%), Gaps = 48/276 (17%)
Query: 4 VSGSRSPDR-EASGSGGRRRSSSKSPKPSKSARSPRGR---RSRSHSCSRSGDRNGLTHQ 59
+S + PD+ E R RS S+ + S+R R R R RSHS SRS R+ +
Sbjct: 233 ISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRR 292
Query: 60 LGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLD 119
SR + RSRS S++R++ + S P S
Sbjct: 293 ---RRSHSRERGRRSRSTSKTRDKKKEDK-----------------EKKRSKTPPKSYST 332
Query: 120 KEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSE 179
R S ++R R R G SPK P +K + S S
Sbjct: 333 ARRSRSASRERRRRRSRSGT--------RSPKKPR-----------SPKRKLSRSPSPRR 373
Query: 180 EEKKKKSSRSKERSKKRR-----KKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKK 234
+K+KK + KERS+ R KKK SK K K S+SD D + + D D + +
Sbjct: 374 HKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYD 433
Query: 235 AKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQ 270
++K++K++K + K + S ++ + S +ES+
Sbjct: 434 SEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESK 469
Score = 61.6 bits (148), Expect = 1e-09
Identities = 58/228 (25%), Positives = 92/228 (40%), Gaps = 21/228 (9%)
Query: 7 SRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQG 66
SRS R S S R R SKSP+ +S RGRRSRS S +R + +
Sbjct: 269 SRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPK 328
Query: 67 SRNQSYRSRSRSRSRER---------PSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSL 117
S + + RSRS SR R R P PR P S S + + DK
Sbjct: 329 SYSTARRSRSASRERRRRRSRSGTRSPKKPRS-PKRKLSRSPSPRRHKKEKKKDK----- 382
Query: 118 LDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSAST 177
DKER R++ S++++ + + E D D D + ++ +
Sbjct: 383 -DKERSRDERERSTSKKKKSKDKEKDR-----ERKSESDKDVKQVTRDYDEEEQGYDSEK 436
Query: 178 SEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSD 225
++E+KK ++K+ +K + ++ + D + + D SD
Sbjct: 437 EKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMDMSD 484
Score = 60.1 bits (144), Expect = 4e-09
Identities = 61/217 (28%), Positives = 93/217 (42%), Gaps = 33/217 (15%)
Query: 73 RSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKRLS 132
RSRSRSR R PS+ R S S + S SR + R +S R++R
Sbjct: 250 RSRSRSRRRRTPSSSRHRRSRSRSRRRSH-SKSR------------SRRRSKSPRRRRSH 296
Query: 133 ERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKER 192
RER G ++ D+ ED+E K+S T + ++ SRS R
Sbjct: 297 SRER----------GRRSRSTSKTRDKKK--EDKEKKRSKTPPKSYSTARR---SRSASR 341
Query: 193 SKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKK 252
++RR+ +S R KK S S S +K+ KK K KE+ + R + KK
Sbjct: 342 ERRRRRSRSGTRSPKKPRSPKRKLSRS---PSPRRHKKEKKKDKDKERSRDERERSTSKK 398
Query: 253 RSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSD 289
KKS+ + D K ++ ++ +D + E+ D
Sbjct: 399 --KKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYD 433
Score = 53.1 bits (126), Expect = 4e-07
Identities = 28/120 (23%), Positives = 58/120 (48%)
Query: 179 EEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKK 238
++E+K++ SRS+ RS++RR SS+ + + S S S + + +RR ++++
Sbjct: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300
Query: 239 EKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSDLIGPEAPKT 298
++ + SK KK+ K +K S S + ++R + S P+ P++
Sbjct: 301 GRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRS 360
Score = 46.2 bits (108), Expect = 5e-05
Identities = 42/154 (27%), Positives = 61/154 (39%), Gaps = 21/154 (13%)
Query: 154 EPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERS-KKRRKKKSSKRKHKKYSED 212
EPD E +S + S ++ SRS+ RS K R ++ SK ++ S
Sbjct: 238 EPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHS 297
Query: 213 SDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEE 272
+ S + S D KKKE K+K RSK K S R S S+S+E +
Sbjct: 298 RERGRRSRSTSKTRD--------KKKEDKEKKRSKTPPKSYSTARR---SRSASRERRRR 346
Query: 273 FLENPWKDRTKAEEPSDLIGPEAPKTLTSQDDKP 306
+ R+ P P +PK S+ P
Sbjct: 347 ------RSRSGTRSPKK---PRSPKRKLSRSPSP 371
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 70.1 bits (170), Expect = 4e-12
Identities = 32/113 (28%), Positives = 65/113 (57%), Gaps = 4/113 (3%)
Query: 151 KNPEPDSDEHTPVEDEEPK----KSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKH 206
K +++E E+EE K K E+EKKKK+ +++R +K ++K KRK
Sbjct: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66
Query: 207 KKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRK 259
KK E+ + + + E + +++ + + + ++K+KKK+ R ++ ++K+ K+ RK
Sbjct: 67 KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119
Score = 67.4 bits (163), Expect = 2e-11
Identities = 34/118 (28%), Positives = 64/118 (54%), Gaps = 8/118 (6%)
Query: 151 KNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRR-------KKKSSK 203
K E + E T +EE +K +E++K+K + K + ++R KK+ K
Sbjct: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65
Query: 204 RKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEK-KKKHRSKKYKKKRSKKSRKE 260
RK KK E+ + + + E + +E+ K ++ KKK+K ++K ++ KKKR +K++K+
Sbjct: 66 RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 58.5 bits (140), Expect = 1e-08
Identities = 30/121 (24%), Positives = 61/121 (50%), Gaps = 11/121 (9%)
Query: 169 KKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDN 228
KK T E E+ +++ +E+ KR++K+ KRK K+ + + E
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKK-----------KTKETE 50
Query: 229 KRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPS 288
KR+ K+ ++K++K+K + KK +++R ++ +E + +E +E K R + EE
Sbjct: 51 KRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110
Query: 289 D 289
+
Sbjct: 111 E 111
Score = 54.3 bits (129), Expect = 2e-07
Identities = 24/121 (19%), Positives = 63/121 (52%)
Query: 166 EEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSD 225
++ KK + T E E+ ++ + + K++RK+K +++ KK +++++ + E +
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 226 EDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAE 285
KR+ KK +++ ++++ ++ K++ K+ + + +EE E K R K +
Sbjct: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121
Query: 286 E 286
+
Sbjct: 122 K 122
Score = 53.1 bits (126), Expect = 4e-07
Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Query: 192 RSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKK 251
+ KK++KK++ + + + +E+ + + E K + KK K KE +K+ ++ +K
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 252 KRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
KR +K +K+ + +E +EE E K+ + EE
Sbjct: 61 KRKRKRKKKKEEEEREEEEEE--EEEEKEEEEKEE 93
Score = 50.8 bits (120), Expect = 2e-06
Identities = 25/87 (28%), Positives = 46/87 (52%), Gaps = 2/87 (2%)
Query: 203 KRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESS 262
K+K KK E +++ ET+ +E+ K +K K+KEK+K+ KK K+ K+ KE
Sbjct: 1 KKKKKKKKETEETEETEETE--EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE 58
Query: 263 DSSSKESQEEFLENPWKDRTKAEEPSD 289
+ K +++ E ++ + EE +
Sbjct: 59 EKKRKRKRKKKKEEEEREEEEEEEEEE 85
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/119 (21%), Positives = 50/119 (42%), Gaps = 15/119 (12%)
Query: 120 KEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSE 179
+E EE +++ +E+ E + + K E + +E + KK E
Sbjct: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEE 79
Query: 180 EEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKK 238
EE++++ ++ +RRKKK +R+ + +E K+R +K KKK
Sbjct: 80 EEEEEEKEEEEKEEGRRRKKKKKRRR---------------KEEEEEKKKKRRRKTKKK 123
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 68.6 bits (166), Expect = 1e-11
Identities = 86/314 (27%), Positives = 121/314 (38%), Gaps = 38/314 (12%)
Query: 7 SRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQ-LGGLSQ 65
SR R S S R SS+S SKS+ R R S+S S S+SG R + SQ
Sbjct: 515 SRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSR-SKSRSSSKSGHRKRASKSPRKTASQ 573
Query: 66 GSRNQSYRS---RSRSRSRE----RPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLL 118
S N+ ++ R+ E +P IP S S SR KPW
Sbjct: 574 LSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSP---PPSRWKPGQKPWKPSY 630
Query: 119 DKEREESLRQKRLSERE------RIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKST 172
++ +E + L + I E G+ + KN E D ++ D + S
Sbjct: 631 ERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSP 690
Query: 173 TSASTSEEEKKKKSSRSKERS---KKRRKKKSSKRKHK--KYSEDSDSDSDSETDSSDED 227
S S S + S ++ RS R + S R H KYS+ S S S D
Sbjct: 691 RSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSD 750
Query: 228 NKRRAKKAKKKEKK------KKHRS-------KKYKKKRSKKS--RKESSDSSSKESQEE 272
+ RRAK+ + K KKH S KY K R + S RK S SS + +
Sbjct: 751 DGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSD 810
Query: 273 FLENPWKDRTKAEE 286
++ + A+E
Sbjct: 811 SEQSSVQATQSAQE 824
Score = 60.8 bits (146), Expect = 2e-09
Identities = 86/322 (26%), Positives = 126/322 (39%), Gaps = 44/322 (13%)
Query: 5 SGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLS 64
S S RE + + S S + S+S+ R R SRS S SRS R + L
Sbjct: 660 SSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTR---SRSLASSH 716
Query: 65 QGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKER-- 122
SR+ S RS SR++ + R + S SS + R S K S+ K+
Sbjct: 717 SRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKK-NSVSHKKHSS 775
Query: 123 --EESLRQKRLSERER---IGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSAST 177
E++L K + R+R + + + E S + T E+ K+ +
Sbjct: 776 SSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTH 835
Query: 178 SEEEK-----KKKSSRSKERSKKRRKKKS--------SKRKHKKYSEDS-DSDSDSETDS 223
+++EK K KS R SKKR K++ SK K K Y+ DS+S+SE D
Sbjct: 836 NKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERD- 894
Query: 224 SDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENP-WKDRT 282
K K H S K+ + +SDS S+ S+ P K T
Sbjct: 895 -----------VTKNSKNDSHPSS------DKEEGEATSDSESEVSEIHIKVKPTTKSST 937
Query: 283 KAEEPSDLIGPEAPKTLTSQDD 304
P D ++ K TS D
Sbjct: 938 NTSLPDDNGAWKSSKQRTSTSD 959
Score = 55.1 bits (131), Expect = 1e-07
Identities = 90/403 (22%), Positives = 144/403 (35%), Gaps = 36/403 (8%)
Query: 5 SGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLS 64
S S + E RRR + PK +S ++ R + S RN G S
Sbjct: 207 SSESSSESELEHERSRRRKHKRRPKVKRS------KKRRKEASSSEEPRNKHAMNPKGHS 260
Query: 65 QGSRNQSYRSRSRSRSRERPSA-PRGIPFASASSSVYYGSYSRPYGSDKPWPSL------ 117
+ S RS S RE+P P IP + + P + +P P +
Sbjct: 261 ERSDTNEKRSVDSSAKREKPVVRPEEIP--PVPENRFLLRRDMPVVTAEPEPKIPDVAPI 318
Query: 118 -LDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSAS 176
D++ S +++ R I P S + D TP +E + +
Sbjct: 319 VSDQKPSVSKSGRKIKGRGTIRYHTPPR--SRSCSESDDDDSSETPPHWKEEMQRLRAYR 376
Query: 177 TSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKA- 235
EK K + + R ++S ++ + +S + S S KRR +K
Sbjct: 377 PPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKV 436
Query: 236 --KKKEKKKKH--RSKKYKKKRSK-KSRKESSDSSSKESQEEFLENPWKDRTKAEEPSDL 290
KKK KK+KH R K+ KK+R S ESS SS++ + DR ++ S L
Sbjct: 437 KHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSC------DRERSSRSSSL 490
Query: 291 IGPEAPKTLTSQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECS 350
+ K S+ DK + + + ++ R R S +
Sbjct: 491 SSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSK 550
Query: 351 GYVMSGSRHRRMEAVRLRK------ENQIYSADEKRALASFNQ 387
S S HR+ + RK EN+ + RA + N+
Sbjct: 551 SRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNE 593
Score = 51.6 bits (122), Expect = 1e-06
Identities = 80/338 (23%), Positives = 122/338 (36%), Gaps = 56/338 (16%)
Query: 5 SGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGG-- 62
S SRS R + S S S+S PS + S R + S CSRS ++ G
Sbjct: 697 SRSRSYSRSYTRSRSLASSHSRSRSPSSRSHS-RNKYSDHSQCSRSSSYTSISSDDGRRA 755
Query: 63 ---LSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRP---YGSDKPWPS 116
L + S + S S E+ + + SS V S SR Y SD S
Sbjct: 756 KRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSS 815
Query: 117 LL------------DKEREESLRQKRLSERERIGELGAPEVW--------------GLSP 150
+ ER + ++K E + E P G P
Sbjct: 816 VQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKP 875
Query: 151 KNPEP-----DSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRK 205
K DS+ ++ + + K+ + S+ +EE + S E S+ K K + +
Sbjct: 876 KRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKS 935
Query: 206 HK-----------KYSEDSDSDSDSETDSSDEDNKRRAKKAKK---KEKKKKHRSKKYKK 251
K S+ S SDSE S+ +N R + K KE K+ +KK K+
Sbjct: 936 STNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKE 995
Query: 252 KRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSD 289
K K +K+ + K Q + P + + EE D
Sbjct: 996 K--LKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEID 1031
Score = 49.7 bits (117), Expect = 5e-06
Identities = 42/159 (26%), Positives = 62/159 (38%), Gaps = 40/159 (25%)
Query: 150 PKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKK----------------------SS 187
P+N E SDE TP D++ + + S S S+ E K + S
Sbjct: 1291 PRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRS 1350
Query: 188 RSKERSKKR--------RKKKSSKRKHKKY---------SEDSDSDSDSETDSSDEDNKR 230
RS RS+ R R + SS R +K + S D S S + + D R
Sbjct: 1351 RSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSR 1410
Query: 231 RAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKES 269
+++ + HR + Y +RS+ R SDS S S
Sbjct: 1411 SRSRSRSQRSDSYHRGRSY-NRRSRSCRSYGSDSESDRS 1448
Score = 46.6 bits (109), Expect = 4e-05
Identities = 29/75 (38%), Positives = 47/75 (62%), Gaps = 6/75 (8%)
Query: 203 KRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESS 262
KRK +SE SDS S+S SS ++ ++ ++ +++KH+ ++ K KRSKK RKE+
Sbjct: 188 KRKKPTHSEGSDSSSNS---SSSSESSSESELEHERSRRRKHK-RRPKVKRSKKRRKEA- 242
Query: 263 DSSSKESQEEFLENP 277
SSS+E + + NP
Sbjct: 243 -SSSEEPRNKHAMNP 256
Score = 43.5 bits (101), Expect = 4e-04
Identities = 46/113 (40%), Positives = 54/113 (47%), Gaps = 22/113 (19%)
Query: 5 SGSRSPDREAS----GSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQL 60
S SRSP R S S R RS S S S+S S RSRS+S SRS
Sbjct: 1309 SQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRS---------R 1359
Query: 61 GGLSQG---SRNQSYRS----RSRSRSRERPSAPRGIPFASASSSVYYGSYSR 106
G S+G SR+ SYRS R+ SRSR R S+ P + + S Y YSR
Sbjct: 1360 GWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYD--PHSRSRSYTYDSYYSR 1410
Score = 42.4 bits (98), Expect = 8e-04
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 8/84 (9%)
Query: 194 KKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSK------ 247
KKR+K S+ + S S+S SE++ E ++RR K + K K+ K R K
Sbjct: 187 KKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSE 246
Query: 248 --KYKKKRSKKSRKESSDSSSKES 269
+ K + K E SD++ K S
Sbjct: 247 EPRNKHAMNPKGHSERSDTNEKRS 270
Score = 41.2 bits (95), Expect = 0.002
Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 5/86 (5%)
Query: 160 HTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDS 219
H+ D S++S S+SE E + + SR ++ ++ + K+S KR+ + S + + +
Sbjct: 194 HSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHA 253
Query: 220 -----ETDSSDEDNKRRAKKAKKKEK 240
++ SD + KR + K+EK
Sbjct: 254 MNPKGHSERSDTNEKRSVDSSAKREK 279
Score = 39.7 bits (91), Expect = 0.005
Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 13/106 (12%)
Query: 166 EEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSD 225
E+ +K T + S+ SS + ++S +RKHK+ + S
Sbjct: 186 EKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRS---------- 235
Query: 226 EDNKRRAKKAKKKEKKKKH-RSKKYKKKRSKKSRKESSDSSSKESQ 270
KRR + + +E + KH + K +RS + K S DSS+K +
Sbjct: 236 --KKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREK 279
Score = 38.1 bits (87), Expect = 0.015
Identities = 59/217 (27%), Positives = 75/217 (34%), Gaps = 57/217 (26%)
Query: 21 RRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQG-------SRNQSYR 73
+ SSS PS+ S +SRS S SRS H+ +S S SYR
Sbjct: 1294 QESSSDEQTPSRDDDS----QSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYR 1349
Query: 74 SRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKRLSE 133
SRS SRSR R RG + S S Y SY + R S
Sbjct: 1350 SRSYSRSRSRGWYSRG---RTRSRSSSYRSY----------------------KSHRTSS 1384
Query: 134 RERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERS 193
R R S +P S +T S S S S ++ S + RS
Sbjct: 1385 RSRSRS---------SSYDPHSRSRSYT-------YDSYYSRSRSRSRSQRSDSYHRGRS 1428
Query: 194 KKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKR 230
RR R + Y DS+SD S ++ R
Sbjct: 1429 YNRR-----SRSCRSYGSDSESDRSYSHHRSPSESSR 1460
Score = 37.7 bits (86), Expect = 0.019
Identities = 59/295 (20%), Positives = 106/295 (35%), Gaps = 52/295 (17%)
Query: 24 SSKSPKPSKSARSPRGRRS-------RSHSCSRSGDRNGLTHQLGGLSQGSRNQSYRSRS 76
S + P SKS R +GR + RS SCS S D + + R ++YR S
Sbjct: 320 SDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPS 379
Query: 77 --------------RSRSRERPSAPRGIPFA-----SASSSVYYGSYSRPYGSDKPWPSL 117
SR ER + R ++ S S+ + + + +K
Sbjct: 380 GEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHK 439
Query: 118 LDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDE-EPKKSTTSAS 176
++++ R+ + +++ RI L P + E ++ + ++S+ S+S
Sbjct: 440 KKGKKQKHCRRHKQTKKRRI----------LIPSDIESSKSSTRRMKSSCDRERSSRSSS 489
Query: 177 TSEEEKKKK---------------SSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSET 221
S K+ SSR RSK + S + + S S S S +
Sbjct: 490 LSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRS 549
Query: 222 DSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLEN 276
S K+A K +K + + K +++ R + + + Q EN
Sbjct: 550 KSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAEN 604
Score = 37.7 bits (86), Expect = 0.019
Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 17/136 (12%)
Query: 168 PKKSTTSAS-----TSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSE------DSDSD 216
P +T+SA T+ E K + R + +SK + + S + +K + + +S
Sbjct: 1238 PNAATSSAVEVKVLTTVPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESS 1297
Query: 217 SDSETDSSDEDNKRRA--KKAKKKEKKKKHRSKK--YKKKRSKKSRKESSDSSSKESQEE 272
SD +T S D+D++ R+ + K E K +HR++ Y RS+ + S+ S S
Sbjct: 1298 SDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRS--RSSTSSYRSRSYSR 1355
Query: 273 FLENPWKDRTKAEEPS 288
W R + S
Sbjct: 1356 SRSRGWYSRGRTRSRS 1371
Score = 37.4 bits (85), Expect = 0.025
Identities = 41/110 (37%), Positives = 46/110 (41%), Gaps = 22/110 (20%)
Query: 7 SRSPDREASG---SGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGL 63
SRS R S S GR RS S S + KS R+ RSRS S T+
Sbjct: 1350 SRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYD---- 1405
Query: 64 SQGSRNQSYRSRSRSRSRER--PSAPRGIPFASASSSVYYGSYSRPYGSD 111
SY SRSRSRSR + S RG + S S R YGSD
Sbjct: 1406 -------SYYSRSRSRSRSQRSDSYHRGRSYNRRSRS------CRSYGSD 1442
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 68.6 bits (166), Expect = 1e-11
Identities = 52/176 (29%), Positives = 80/176 (45%), Gaps = 25/176 (14%)
Query: 114 WPSLLDKEREESLRQKRLS--ERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPK-- 169
W L+K RE+ L S +RER + S + S + EDEE K
Sbjct: 69 WKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQG 128
Query: 170 -----KSTTSASTSEEEKKKKSSRSKERSKKRRKKKS-----------SKRKHKKYSEDS 213
K S +S+ + S SKE KK++K K SK++ K Y +D
Sbjct: 129 KRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDK 188
Query: 214 DSDSDSETDSSDEDN-----KRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDS 264
S+S ++S E++ KRR ++ ++ ++K K + KK KK SKK +K+S S
Sbjct: 189 PLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSS 244
Score = 67.4 bits (163), Expect = 2e-11
Identities = 52/155 (33%), Positives = 77/155 (49%), Gaps = 25/155 (16%)
Query: 167 EPKKSTTSASTSEEEK-----KKKSSRSKER--------SKKRRKKKSSKRKHKKYSEDS 213
E KK+ + A EEK KK+ +S+E+ SKKR +KK K KK S
Sbjct: 49 ENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRK---KKSCRSS 105
Query: 214 DSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEF 273
S S S++ SS D++ KK K+ KKKK+RS K + + +S ES +S K+ +
Sbjct: 106 SSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKS-- 163
Query: 274 LENPWKDRTKAEEPSDLIGPEAPKTLTSQDDKPLN 308
KD T+ E+ + + K+ DDKPL+
Sbjct: 164 -----KDETEKEKDVRSLSKKRKKSY--PDDKPLS 191
Score = 62.8 bits (151), Expect = 6e-10
Identities = 40/119 (33%), Positives = 63/119 (52%), Gaps = 2/119 (1%)
Query: 169 KKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDN 228
KKS S+S+S SS E +K++ K+ K+K++ Y S +SE++S E
Sbjct: 99 KKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESK-ESV 157
Query: 229 KRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKE-SSDSSSKESQEEFLENPWKDRTKAEE 286
K++ K + EK+K RS K+K+S K SS+SSS+ EE ++ K R + E
Sbjct: 158 KKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEERE 216
Score = 46.2 bits (108), Expect = 5e-05
Identities = 53/220 (24%), Positives = 90/220 (40%), Gaps = 51/220 (23%)
Query: 8 RSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQGS 67
+S ++ SG+ + + K K + S S S S S D + G +
Sbjct: 75 KSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKK 134
Query: 68 RNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLR 127
+N+SY+S S+S + E S E +ES++
Sbjct: 135 KNRSYKS-SQSSTHESES-----------------------------------ESKESVK 158
Query: 128 QKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEE----KK 183
+K+ S+ E E +V LS K + D++P S +S+ + EE KK
Sbjct: 159 KKKKSKDETEKE---KDVRSLSKKRKK-------SYPDDKPLSSESSSESDYEEDVQAKK 208
Query: 184 KKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDS 223
K+ +E++K++ KKK K++HKK+S+ S S S
Sbjct: 209 KRRCEEREQAKEKVKKK-KKKQHKKHSKKKKKKSGSSHKS 247
>gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo
sapiens]
Length = 1045
Score = 68.2 bits (165), Expect = 1e-11
Identities = 87/348 (25%), Positives = 130/348 (37%), Gaps = 69/348 (19%)
Query: 5 SGSRSPDREASGSGGRRRSSSKSPKPSKSARS-----PRGRRSRSHSCSRSGDRNGLTHQ 59
S SRS R R+ K SK +RS PRGRR + S +R
Sbjct: 600 SDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSS------- 652
Query: 60 LGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLL- 118
S+ S+ S S S SRSR R S S + YY YGS W
Sbjct: 653 ---WSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYY--LRNNYGSRYKWEYTYY 707
Query: 119 --DKER---EESLRQKRLSERERIGELGAPE--VWGLSPKNPEPDSDEHTP--------- 162
+K+R E S R++ LS + +PE V S + + H+
Sbjct: 708 SRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERH 767
Query: 163 -------------------VEDEEP---KKSTTSASTSEEEKKKKSSRSKERSKKRRKKK 200
V +E+P +K T E + S ++K +K
Sbjct: 768 RSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQK 827
Query: 201 SSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAK----------KKEKKKKHRSKKYK 250
SS + Y +SD+ SDS + + +KRR +K + K KH KK K
Sbjct: 828 SSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKK-K 886
Query: 251 KKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPS--DLIGPEAP 296
KK KK +K D++S+ +++ ++ +E + D GP+ P
Sbjct: 887 KKHKKKHKKHHGDNASRSPVVITIDSDSDKDSEVKEDTECDNSGPQDP 934
Score = 49.3 bits (116), Expect = 6e-06
Identities = 37/132 (28%), Positives = 65/132 (49%), Gaps = 11/132 (8%)
Query: 164 EDEEPKKSTTSAST---SEEEKKKKSSRSKERS-----KKRRKKKSSKRKHKKYSEDSDS 215
+DE+ K +ST S++E+K+ +S S R+ + R +H+K S
Sbjct: 541 KDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSS 600
Query: 216 DSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKES--SDSS-SKESQEE 272
DS S++ S + R KK+ K K+ RS++ + R ++ +K S DSS S+ SQ
Sbjct: 601 DSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTL 660
Query: 273 FLENPWKDRTKA 284
L + R+++
Sbjct: 661 SLSSESTSRSRS 672
Score = 37.0 bits (84), Expect = 0.033
Identities = 28/138 (20%), Positives = 52/138 (37%)
Query: 123 EESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEK 182
+ S R K E +R L +P S + S + +S+ S S S
Sbjct: 551 DSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGH 610
Query: 183 KKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKK 242
+K+ R K+ + K+S R+ + D DSS + + + +
Sbjct: 611 DQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRS 670
Query: 243 KHRSKKYKKKRSKKSRKE 260
+ RS + K+RS+ ++
Sbjct: 671 RSRSSDHGKRRSRSRNRD 688
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 67.8 bits (164), Expect = 2e-11
Identities = 74/274 (27%), Positives = 117/274 (42%), Gaps = 35/274 (12%)
Query: 15 SGSGGRRRSSSKSPKPSKS-----ARSP--RGRRSRSHSCSR--SGDRNGLTHQLGGLSQ 65
S S G R+SS+S P + +RSP + RRSRS S SR + N ++ +
Sbjct: 537 SSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRR 596
Query: 66 GSRNQSYRSRSRSRSRERP-------SAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLL 118
+RN R R R+RS R S R AS S S G+
Sbjct: 597 SNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGN---LSGNS 653
Query: 119 DKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTS 178
K + E+ Q+R ER R + + K E + D+ + E K S+
Sbjct: 654 HKHKGEAKEQERKKERSRSIDKDRKK----KDKEREREQDKRKEKQKREEKDFKFSSQDD 709
Query: 179 EEEKKKKSSRSKERS-----------KKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDED 227
++K++S R+ RS ++ KKS+ + KK+S SDS S ++S
Sbjct: 710 RLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHS-GSDSSGRSSSESPGSS 768
Query: 228 NKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKES 261
+++AKK K + +S++ KK S+K + +S
Sbjct: 769 KEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKS 802
Score = 65.1 bits (157), Expect = 1e-10
Identities = 51/227 (22%), Positives = 96/227 (42%), Gaps = 13/227 (5%)
Query: 68 RNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLR 127
+ + + RSRS S S+ +S SS+V SYS GS + R S +
Sbjct: 500 KEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT------SSRSSSPK 553
Query: 128 QKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSS 187
+K+ R R + A S V+ + ++S ++ E + + S
Sbjct: 554 RKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPS 613
Query: 188 RSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSK 247
R + RS+ R + + + R + S D D + S +K + + K++++KK RS+
Sbjct: 614 RERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEA--KEQERKKERSR 671
Query: 248 KYKKKRSKKSRKESSDSSSKESQEEFLENPWK-----DRTKAEEPSD 289
K R KK ++ + ++ +++ E +K DR K + S+
Sbjct: 672 SIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESE 718
Score = 61.6 bits (148), Expect = 1e-09
Identities = 70/311 (22%), Positives = 120/311 (38%), Gaps = 42/311 (13%)
Query: 7 SRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQG 66
SRS + S R+SS S S S+ S SR+ S S S R + S+
Sbjct: 508 SRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK----KRHSRSRS 563
Query: 67 SRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESL 126
++ RSRSRS SR I S + V R + ++
Sbjct: 564 PTIKARRSRSRSYSRR-------IKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRER 616
Query: 127 RQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTS----ASTSEEEK 182
R+ R R+R + + S + ++D+ S S E+E+
Sbjct: 617 RRSRSRSRDR-----------RTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQER 665
Query: 183 KKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAK------ 236
KK+ SRS ++ +K++ K+ + + K+ + + D + S D+ KR+ + +
Sbjct: 666 KKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSG 725
Query: 237 ----------KKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
++ KK +K KK S SS S S+E+ + P R+++ E
Sbjct: 726 SISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVE 785
Query: 287 PSDLIGPEAPK 297
S G +A +
Sbjct: 786 KSQRSGKKASR 796
Score = 56.6 bits (135), Expect = 4e-08
Identities = 63/223 (28%), Positives = 94/223 (42%), Gaps = 48/223 (21%)
Query: 7 SRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQG 66
+RSP RE RRRS S+S + R+ R RSRS DR + Q G LS
Sbjct: 609 NRSPSRE------RRRSRSRS----RDRRTNRASRSRSR------DRRKIDDQRGNLSGN 652
Query: 67 SRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREES- 125
S ++ + R +ER S S+ + ++ +K++ E
Sbjct: 653 SHKHKGEAKEQERKKER------------SRSIDKDRKKKDKEREREQDKRKEKQKREEK 700
Query: 126 ----------LRQKRLSER--ERIGELGAP----EVWGLSPKNPEPDSDEHTPVEDEEPK 169
L++KR SER R G + + S K+ DS +H+ D +
Sbjct: 701 DFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSG-SDSSGR 759
Query: 170 KSTTSASTSEEEKKKKSSRSKERS--KKRRKKKSSKRKHKKYS 210
S+ S +S+E+K KK S+ RS K +R K + RKHK S
Sbjct: 760 SSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKS 802
Score = 44.7 bits (104), Expect = 2e-04
Identities = 49/195 (25%), Positives = 73/195 (37%), Gaps = 18/195 (9%)
Query: 111 DKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNP-EPDSD-----EHTPVE 164
+K L DK+ EE +Q +E + E E LS E D D + TP E
Sbjct: 430 EKEQQLLHDKQMEEEKQQTERVTKE-MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNE 488
Query: 165 DE---EPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSET 221
EPKK + SS S R SS YS S S S
Sbjct: 489 TTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSR 548
Query: 222 DSSDEDNKRRAKKAKKKEKKKKHRSKKYKKK--------RSKKSRKESSDSSSKESQEEF 273
SS + KR ++ K ++ RS+ Y ++ R K + S+ +S E +
Sbjct: 549 SSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRR 608
Query: 274 LENPWKDRTKAEEPS 288
+P ++R ++ S
Sbjct: 609 NRSPSRERRRSRSRS 623
Score = 37.7 bits (86), Expect = 0.019
Identities = 47/231 (20%), Positives = 90/231 (38%), Gaps = 8/231 (3%)
Query: 164 EDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDS 223
EDE + + S+ T +EE + + + +E RK+K + H K E+ ++ T
Sbjct: 397 EDERSDRGSESSDTDDEELRHRIRQKQEAFW--RKEKEQQLLHDKQMEEEKQQTERVTKE 454
Query: 224 SDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTK 283
+E + E ++ +KKR+ + +S E ++E E + R++
Sbjct: 455 MNEFIHKEQNSLSLLEAREADGDVVNEKKRT-----PNETTSVLEPKKEHKEKEKQGRSR 509
Query: 284 AEEPSDLIGPEAPKT-LTSQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSE 342
+ S +T TS +Y + ++ + K KR R + +
Sbjct: 510 SGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKAR 569
Query: 343 EIASFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKR 393
S S + S R++ R+ N+ E+R S ++E RR R
Sbjct: 570 RSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSR 620
Score = 31.6 bits (70), Expect = 1.4
Identities = 53/249 (21%), Positives = 94/249 (37%), Gaps = 51/249 (20%)
Query: 179 EEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSD----------SDSDSETDSSDEDN 228
E++KK + KER +++R + S +K KK +ED++ S DS+ + D +N
Sbjct: 246 EKQKKLE----KERMEQQRSQLS--KKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTEN 299
Query: 229 KRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEF---------LENPWK 279
A S K + S ++E SD E ++E+ L
Sbjct: 300 VEAAS------------SGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILL 347
Query: 280 DRTKAEEPSDLIGPEAPKTLTSQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGL 339
D T +E + +A + T K L AL G +G R + G
Sbjct: 348 DVT--DEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGS 405
Query: 340 TSEEIASFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILA 399
S + E RHR +R ++E E++ L EE +++ ++
Sbjct: 406 ESSDTDDEEL--------RHR----IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTK 453
Query: 400 SFREMVYRK 408
E ++++
Sbjct: 454 EMNEFIHKE 462
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 67.8 bits (164), Expect = 2e-11
Identities = 74/274 (27%), Positives = 117/274 (42%), Gaps = 35/274 (12%)
Query: 15 SGSGGRRRSSSKSPKPSKS-----ARSP--RGRRSRSHSCSR--SGDRNGLTHQLGGLSQ 65
S S G R+SS+S P + +RSP + RRSRS S SR + N ++ +
Sbjct: 537 SSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRR 596
Query: 66 GSRNQSYRSRSRSRSRERP-------SAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLL 118
+RN R R R+RS R S R AS S S G+
Sbjct: 597 SNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGN---LSGNS 653
Query: 119 DKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTS 178
K + E+ Q+R ER R + + K E + D+ + E K S+
Sbjct: 654 HKHKGEAKEQERKKERSRSIDKDRKK----KDKEREREQDKRKEKQKREEKDFKFSSQDD 709
Query: 179 EEEKKKKSSRSKERS-----------KKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDED 227
++K++S R+ RS ++ KKS+ + KK+S SDS S ++S
Sbjct: 710 RLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHS-GSDSSGRSSSESPGSS 768
Query: 228 NKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKES 261
+++AKK K + +S++ KK S+K + +S
Sbjct: 769 KEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKS 802
Score = 65.1 bits (157), Expect = 1e-10
Identities = 51/227 (22%), Positives = 96/227 (42%), Gaps = 13/227 (5%)
Query: 68 RNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLR 127
+ + + RSRS S S+ +S SS+V SYS GS + R S +
Sbjct: 500 KEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT------SSRSSSPK 553
Query: 128 QKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSS 187
+K+ R R + A S V+ + ++S ++ E + + S
Sbjct: 554 RKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPS 613
Query: 188 RSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSK 247
R + RS+ R + + + R + S D D + S +K + + K++++KK RS+
Sbjct: 614 RERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEA--KEQERKKERSR 671
Query: 248 KYKKKRSKKSRKESSDSSSKESQEEFLENPWK-----DRTKAEEPSD 289
K R KK ++ + ++ +++ E +K DR K + S+
Sbjct: 672 SIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESE 718
Score = 61.6 bits (148), Expect = 1e-09
Identities = 70/311 (22%), Positives = 120/311 (38%), Gaps = 42/311 (13%)
Query: 7 SRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQG 66
SRS + S R+SS S S S+ S SR+ S S S R + S+
Sbjct: 508 SRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK----KRHSRSRS 563
Query: 67 SRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESL 126
++ RSRSRS SR I S + V R + ++
Sbjct: 564 PTIKARRSRSRSYSRR-------IKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRER 616
Query: 127 RQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTS----ASTSEEEK 182
R+ R R+R + + S + ++D+ S S E+E+
Sbjct: 617 RRSRSRSRDR-----------RTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQER 665
Query: 183 KKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAK------ 236
KK+ SRS ++ +K++ K+ + + K+ + + D + S D+ KR+ + +
Sbjct: 666 KKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSG 725
Query: 237 ----------KKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286
++ KK +K KK S SS S S+E+ + P R+++ E
Sbjct: 726 SISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVE 785
Query: 287 PSDLIGPEAPK 297
S G +A +
Sbjct: 786 KSQRSGKKASR 796
Score = 56.6 bits (135), Expect = 4e-08
Identities = 63/223 (28%), Positives = 94/223 (42%), Gaps = 48/223 (21%)
Query: 7 SRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQG 66
+RSP RE RRRS S+S + R+ R RSRS DR + Q G LS
Sbjct: 609 NRSPSRE------RRRSRSRS----RDRRTNRASRSRSR------DRRKIDDQRGNLSGN 652
Query: 67 SRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREES- 125
S ++ + R +ER S S+ + ++ +K++ E
Sbjct: 653 SHKHKGEAKEQERKKER------------SRSIDKDRKKKDKEREREQDKRKEKQKREEK 700
Query: 126 ----------LRQKRLSER--ERIGELGAP----EVWGLSPKNPEPDSDEHTPVEDEEPK 169
L++KR SER R G + + S K+ DS +H+ D +
Sbjct: 701 DFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSG-SDSSGR 759
Query: 170 KSTTSASTSEEEKKKKSSRSKERS--KKRRKKKSSKRKHKKYS 210
S+ S +S+E+K KK S+ RS K +R K + RKHK S
Sbjct: 760 SSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKS 802
Score = 44.7 bits (104), Expect = 2e-04
Identities = 49/195 (25%), Positives = 73/195 (37%), Gaps = 18/195 (9%)
Query: 111 DKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNP-EPDSD-----EHTPVE 164
+K L DK+ EE +Q +E + E E LS E D D + TP E
Sbjct: 430 EKEQQLLHDKQMEEEKQQTERVTKE-MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNE 488
Query: 165 DE---EPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSET 221
EPKK + SS S R SS YS S S S
Sbjct: 489 TTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSR 548
Query: 222 DSSDEDNKRRAKKAKKKEKKKKHRSKKYKKK--------RSKKSRKESSDSSSKESQEEF 273
SS + KR ++ K ++ RS+ Y ++ R K + S+ +S E +
Sbjct: 549 SSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRR 608
Query: 274 LENPWKDRTKAEEPS 288
+P ++R ++ S
Sbjct: 609 NRSPSRERRRSRSRS 623
Score = 37.7 bits (86), Expect = 0.019
Identities = 47/231 (20%), Positives = 90/231 (38%), Gaps = 8/231 (3%)
Query: 164 EDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDS 223
EDE + + S+ T +EE + + + +E RK+K + H K E+ ++ T
Sbjct: 397 EDERSDRGSESSDTDDEELRHRIRQKQEAFW--RKEKEQQLLHDKQMEEEKQQTERVTKE 454
Query: 224 SDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTK 283
+E + E ++ +KKR+ + +S E ++E E + R++
Sbjct: 455 MNEFIHKEQNSLSLLEAREADGDVVNEKKRT-----PNETTSVLEPKKEHKEKEKQGRSR 509
Query: 284 AEEPSDLIGPEAPKT-LTSQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSE 342
+ S +T TS +Y + ++ + K KR R + +
Sbjct: 510 SGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKAR 569
Query: 343 EIASFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKR 393
S S + S R++ R+ N+ E+R S ++E RR R
Sbjct: 570 RSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSR 620
Score = 31.6 bits (70), Expect = 1.4
Identities = 53/249 (21%), Positives = 94/249 (37%), Gaps = 51/249 (20%)
Query: 179 EEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSD----------SDSDSETDSSDEDN 228
E++KK + KER +++R + S +K KK +ED++ S DS+ + D +N
Sbjct: 246 EKQKKLE----KERMEQQRSQLS--KKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTEN 299
Query: 229 KRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEF---------LENPWK 279
A S K + S ++E SD E ++E+ L
Sbjct: 300 VEAAS------------SGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILL 347
Query: 280 DRTKAEEPSDLIGPEAPKTLTSQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGL 339
D T +E + +A + T K L AL G +G R + G
Sbjct: 348 DVT--DEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGS 405
Query: 340 TSEEIASFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILA 399
S + E RHR +R ++E E++ L EE +++ ++
Sbjct: 406 ESSDTDDEEL--------RHR----IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTK 453
Query: 400 SFREMVYRK 408
E ++++
Sbjct: 454 EMNEFIHKE 462
>gi|27883882 P18SRP protein [Homo sapiens]
Length = 155
Score = 67.4 bits (163), Expect = 2e-11
Identities = 38/107 (35%), Positives = 59/107 (55%), Gaps = 7/107 (6%)
Query: 171 STTSASTSEEEKKK-------KSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDS 223
S+TS+ S+EE ++ + R E +K+++K K K KK + S S S +E D+
Sbjct: 45 SSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDT 104
Query: 224 SDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQ 270
S + ++ KK KKKEKK K + K+ KK KK +KE S+ S+
Sbjct: 105 SKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
Score = 53.1 bits (126), Expect = 4e-07
Identities = 36/114 (31%), Positives = 53/114 (46%), Gaps = 9/114 (7%)
Query: 157 SDEHTPVEDEEPKKSTTSAS---TSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDS 213
S E + E+EE K EEEKKK+ S+ K + KK+RK+ S S
Sbjct: 48 SSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSS------SSTE 101
Query: 214 DSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSK 267
+ S + + K++ KK+K K+ K + KK +KK S SS+ S K
Sbjct: 102 EDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
Score = 44.3 bits (103), Expect = 2e-04
Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 7/101 (6%)
Query: 119 DKEREE-----SLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTT 173
D+E EE +L++KR++E E + + E L K S T + + KK
Sbjct: 53 DEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKY 112
Query: 174 SASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSD 214
++EKK KS + K K+++K+K K KH S+
Sbjct: 113 QKKEKKKEKKSKSKKGKHHKKEKKKRK--KEKHSSTPNSSE 151
Score = 43.9 bits (102), Expect = 3e-04
Identities = 23/79 (29%), Positives = 43/79 (54%)
Query: 210 SEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKES 269
S S DSD E + ++ + K+ ++E+KKK +SK+ K + K+ R SS S+ +++
Sbjct: 45 SSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDT 104
Query: 270 QEEFLENPWKDRTKAEEPS 288
++ + K K E+ S
Sbjct: 105 SKQKKQKYQKKEKKKEKKS 123
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 65.9 bits (159), Expect = 7e-11
Identities = 43/143 (30%), Positives = 71/143 (49%), Gaps = 19/143 (13%)
Query: 164 EDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDS 223
ED+ +K TT + + ++ KK S + K+ K + +K +K+ KK +D++ DS T+S
Sbjct: 119 EDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATES 178
Query: 224 SDEDNKRRAKKAKKKEKKKKHRSK-----------------KYKKKRSKKSRKESSDSSS 266
ED K AKK KK+KK ++ K K KK SKK + + + +
Sbjct: 179 --EDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQA 236
Query: 267 KESQEEFLENPWKDRTKAEEPSD 289
++ E+ E+ KD K +E D
Sbjct: 237 VKADEKKDEDGKKDANKGDESKD 259
Score = 57.0 bits (136), Expect = 3e-08
Identities = 55/197 (27%), Positives = 83/197 (42%), Gaps = 45/197 (22%)
Query: 118 LDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDE----------- 166
++K +EE L K+ S++ + K+ E D T EDE
Sbjct: 147 IEKGKEEKLDAKKDSKKGK--------------KDAEKGKDSATESEDEKGGAKKDNKKD 192
Query: 167 --EPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSS 224
+ K SA+ SE EK SK+ K +K K S + + D D D + D++
Sbjct: 193 KKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDAN 252
Query: 225 DEDNKRRAKK-AK-----KKEKKK------------KHRSKKYKKKRSKKSRKESSDSSS 266
D + AKK AK KK+KKK K SKK K +KK K+ ++ S
Sbjct: 253 KGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKES 312
Query: 267 KESQEEFLENPWKDRTK 283
+S+++ +N KD K
Sbjct: 313 ADSKKDAKKNAKKDAKK 329
Score = 55.8 bits (133), Expect = 7e-08
Identities = 40/137 (29%), Positives = 69/137 (50%), Gaps = 3/137 (2%)
Query: 123 EESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEK 182
++S + K+ S++ + + V K+ + D + E ++ KK +++K
Sbjct: 215 KDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDK 274
Query: 183 KKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKK 242
KK SS + SK KK+S K K + + D++ E+ S +D K+ AKK KK+ KK
Sbjct: 275 KKPSSTDSD-SKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKK 333
Query: 243 KHRSKKYKKKRSKKSRK 259
+KK +KK +KK K
Sbjct: 334 --NAKKDEKKDAKKKGK 348
Score = 55.5 bits (132), Expect = 9e-08
Identities = 44/158 (27%), Positives = 73/158 (46%), Gaps = 12/158 (7%)
Query: 120 KEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSE 179
K++++S + K S E GE G E K+ + + +D + A +
Sbjct: 191 KDKKDSNKGKD-SATESEGEKGGTE------KDSKKGKKDSKKGKDSAIELQAVKADEKK 243
Query: 180 EEKKKKSSRSKERSKKRRKKKSSKRKHKK-YSEDSDSDSDSETDSSDEDNKRRAKKAKKK 238
+E KK + + SK +K +K KK + S +DSDS+ D E K K AKK
Sbjct: 244 DEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKV 303
Query: 239 EKKKKHR----SKKYKKKRSKKSRKESSDSSSKESQEE 272
KK + SKK KK +KK K+ + ++K+ +++
Sbjct: 304 AKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKK 341
Score = 35.0 bits (79), Expect = 0.13
Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
Query: 203 KRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESS 262
K+ K ++ +DS+SE +D+K+ K KE+K + K K+ + K+S+
Sbjct: 116 KKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSA 175
Query: 263 DSSSKESQEEFLENPWKDRTKAEEPSD-LIGPEAPKTLTSQDDK 305
S E +N KD+ + + D E K T +D K
Sbjct: 176 TESEDEKGGAKKDNK-KDKKDSNKGKDSATESEGEKGGTEKDSK 218
Score = 34.7 bits (78), Expect = 0.16
Identities = 25/125 (20%), Positives = 50/125 (40%), Gaps = 19/125 (15%)
Query: 119 DKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTS 178
+K+ E+ + + + + A E+ +P S + +D + + + +
Sbjct: 241 EKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDA 300
Query: 179 EEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKK 238
++ KK + + SKK KK + K + +D K+ AKK +KK
Sbjct: 301 KKVAKKDTEKESADSKKDAKKNAKK-------------------DAKKDAKKNAKKDEKK 341
Query: 239 EKKKK 243
+ KKK
Sbjct: 342 DAKKK 346
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 65.1 bits (157), Expect = 1e-10
Identities = 69/310 (22%), Positives = 113/310 (36%), Gaps = 57/310 (18%)
Query: 2 APVSGSRSPD---REASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTH 58
AP SGS +E GS G + PSK RS + R + + ++ H
Sbjct: 632 APASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKH 691
Query: 59 QLGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLL 118
+ + +S ++ S +S++R R +SA + G P GS P P
Sbjct: 692 KAD-----TEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRR 746
Query: 119 DKEREESLRQKRLSERERIGELGAPEVWG------------------------------- 147
+ ++ +++ L E G G + G
Sbjct: 747 RRRAQDDSQRRSLPAEE--GSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRS 804
Query: 148 ------LSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKS 201
P + + DSD+ + +KS + S EEE+ S S+ RS+ R+ S
Sbjct: 805 SRSSHRSQPSSGDEDSDDAS--SHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSS 862
Query: 202 SKRKHKKYSEDSDSDSD--------SETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKR 253
+ + YS SD+ SD S +D S D R+++ K+ K R
Sbjct: 863 HRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHR 922
Query: 254 SKKSRKESSD 263
SK+ + SSD
Sbjct: 923 SKRHKYSSSD 932
Score = 53.5 bits (127), Expect = 3e-07
Identities = 67/296 (22%), Positives = 104/296 (35%), Gaps = 40/296 (13%)
Query: 2 APVSGSRSPDREASGSGG------RRRSSSKSPKPSKSARS-PRGRRSRSHSCSRSGDRN 54
AP R P E GSG RRR+ S + S A G++ S S D
Sbjct: 723 APADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHG 782
Query: 55 GLTHQLGGLSQGS--RNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDK 112
G H+ G L S R + SRS R +PS+ ++S ++ S S+
Sbjct: 783 GRKHK-GELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQ------ 835
Query: 113 PWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKST 172
++E EE + R R G + + D+ + S
Sbjct: 836 ----YSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSD 891
Query: 173 TSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSD------SDSDSETDSSDE 226
S S + ++ S RS + + K KYS D S S S + S
Sbjct: 892 DSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTR 951
Query: 227 DNKR-----RAKKAKKKEKKKK---------HRSKKYKKKRSKKSRKESSDSSSKE 268
+ R R+ + K++ RS+ Y + RS+ +R S S S++
Sbjct: 952 ERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRK 1007
Score = 52.8 bits (125), Expect = 6e-07
Identities = 66/278 (23%), Positives = 101/278 (36%), Gaps = 45/278 (16%)
Query: 64 SQGSRNQSYRSRSRSRSRERPSAPRG--IPFASASSSVYYGSYSRPYGSDKPWPSL---- 117
S S+ S + + S+E P P G P S S S K PS+
Sbjct: 510 SNSSKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSC 569
Query: 118 ------LDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEH----------- 160
R + R K + + IG + GL P P +
Sbjct: 570 NPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGR 629
Query: 161 ----------TPVEDEEPKKS----TTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKH 206
+ + +EP S T S KK++S +S KK++ KKSSK K
Sbjct: 630 MDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKR 689
Query: 207 KKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSS 266
K +D+E SS ++ ++KK KK+++KK S +R K S S +
Sbjct: 690 K-------HKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPA 742
Query: 267 KESQEEFLENPWKDRT-KAEEPSDLIGPEAPKTLTSQD 303
+ ++ + R+ AEE S E +SQD
Sbjct: 743 PPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQD 780
Score = 39.3 bits (90), Expect = 0.007
Identities = 74/307 (24%), Positives = 111/307 (36%), Gaps = 53/307 (17%)
Query: 7 SRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQG 66
S S D + S RR S +S S + RS+ H S S D + L
Sbjct: 888 SYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDD----DYSLSCSQSR 943
Query: 67 SRNQSY---RSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKERE 123
SR++S+ RSRSR RSR + S S++ + SR Y D+ R
Sbjct: 944 SRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSR--------DRSRS 995
Query: 124 ESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKK 183
+R R+R WG E + H+ D K S+
Sbjct: 996 TRSPSQRSGSRKR--------SWG-----HESPEERHSGRRDFIRSK----IYRSQSPHY 1038
Query: 184 KKSSRSKERSKKRRKKKSSKRKHKKYSEDSD--SDSDSETDSSDEDNKRRAKKAKKKEKK 241
+S R + KK + + S++S+ + SE D S ED K
Sbjct: 1039 FRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDK----NSVTAKLLL 1094
Query: 242 KKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE-PSDLIGPEAPKTLT 300
+K +S+K ++K S EE P K K ++ P GP+ P +L
Sbjct: 1095 EKIQSRKVERKPS--------------VSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLG 1140
Query: 301 SQDDKPL 307
++ PL
Sbjct: 1141 NKPVLPL 1147
Score = 38.5 bits (88), Expect = 0.011
Identities = 32/80 (40%), Positives = 41/80 (51%), Gaps = 18/80 (22%)
Query: 5 SGSRSPDREASGSGGRRRSS----SKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQL 60
S SRS RE S S GR RSS S+S + S+S + +RSRS+S R
Sbjct: 944 SRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDR----------- 992
Query: 61 GGLSQGSRNQSYRSRSRSRS 80
S+ +R+ S RS SR RS
Sbjct: 993 ---SRSTRSPSQRSGSRKRS 1009
Score = 36.6 bits (83), Expect = 0.043
Identities = 36/160 (22%), Positives = 61/160 (38%), Gaps = 37/160 (23%)
Query: 150 PKNPEPDSDEHTPVEDEEPKKSTTSA----STSEEEKKKKSSRSKERSKKRRKKKSSKRK 205
P E H + ++ KKS+ + +EE+ K S K + +K+RK+K +K
Sbjct: 663 PSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSS 722
Query: 206 HKKYSEDSDSDSDSETDS---------SDEDNKRRAKKAKKKEKKKK-----------HR 245
SE + S + +D++RR+ A++ KK H
Sbjct: 723 APADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHG 782
Query: 246 SKKYK-------------KKRSKKSRKESSDSSSKESQEE 272
+K+K KRS +S S SS E ++
Sbjct: 783 GRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDD 822
Score = 28.9 bits (63), Expect = 9.0
Identities = 20/81 (24%), Positives = 43/81 (53%), Gaps = 7/81 (8%)
Query: 181 EKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKE- 239
+K+K +++ E + + ++++K+ E D+ +S D +K+R K K++E
Sbjct: 120 DKEKAIAKALEDLRANFYCELCDKQYQKHQE-----FDNHINSYDHAHKQRLKDLKQREF 174
Query: 240 -KKKKHRSKKYKKKRSKKSRK 259
+ RS+K +KK+ K R+
Sbjct: 175 ARNVSSRSRKDEKKQEKALRR 195
>gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]
Length = 352
Score = 64.3 bits (155), Expect = 2e-10
Identities = 50/166 (30%), Positives = 78/166 (46%), Gaps = 15/166 (9%)
Query: 174 SASTSEEEKKKKSSRSKERSKK--RRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRR 231
SASTS+ K + ++ERSK+ RR+ +SS S S S S S + SS + K+R
Sbjct: 160 SASTSQGRKASTAPGAEERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGRKKR 219
Query: 232 AKKAKKKEKKKKHRSKKYKKKRSKKSRKESSD------------SSSKESQEEFLENPWK 279
K K+ KKKK R KK KKK +K+ + + S+ +E L + K
Sbjct: 220 GKYKDKRRKKKKKR-KKLKKKGKEKAEAQQVEALPGPSLDQWHRSAGEEEDGPVLTDEQK 278
Query: 280 DRTKAEEPSDLIGPEAPKTLTSQDDKPLNYGHALLPGEGAAMAEYV 325
R +A +P +A +++ + P L+ G+G + E V
Sbjct: 279 SRIQAMKPMTKEEWDARQSIIRKVVDPETGRTRLIKGDGEVLEEIV 324
Score = 52.8 bits (125), Expect = 6e-07
Identities = 56/215 (26%), Positives = 90/215 (41%), Gaps = 31/215 (14%)
Query: 2 APVSGSRSPDREASGSGGRRRSSSKSPKPSKSAR--SPRGRRSRSHSCSRSGDRNGLTHQ 59
AP+ S R G+ G R S + PS+ A +PR S S R GL+
Sbjct: 57 APLLASAGGGRARDGTWGVRTKGSGAALPSRPASRAAPRPEAS-SPPLPLEKARGGLSGP 115
Query: 60 LGGLSQGSR---NQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPS 116
GG ++G+ RSRSRSRSR R S R +S S S+ + P
Sbjct: 116 QGGRARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQGRKASTA-PG 174
Query: 117 LLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSAS 176
++ ++++ R+ R S S + S++S+S
Sbjct: 175 AEERSKQKARRRTRSS------------------------SSSSSSSSSSSSSSSSSSSS 210
Query: 177 TSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSE 211
+S + +KK+ +R KK++K+K K+K K+ +E
Sbjct: 211 SSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAE 245
>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
Length = 450
Score = 63.9 bits (154), Expect = 3e-10
Identities = 45/150 (30%), Positives = 75/150 (50%), Gaps = 9/150 (6%)
Query: 157 SDEHTPVEDEE-PKKSTTSASTSEEEKK--KKSSRSKERSKKRRKKK----SSKRKHKKY 209
S E+ E EE P+ + T+++++K +K R +++ KK+ +KK S+ KHKK+
Sbjct: 196 SQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKH 255
Query: 210 SEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRS--KKSRKESSDSSSK 267
S S S S + SS E ++ ++ ++KK R K+ K K S S E D S K
Sbjct: 256 KSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKK 315
Query: 268 ESQEEFLENPWKDRTKAEEPSDLIGPEAPK 297
E L + +R KA+E + E+ +
Sbjct: 316 RKLHEELSSSHHNREKAKEKPRFLKHESSR 345
Score = 48.9 bits (115), Expect = 8e-06
Identities = 34/139 (24%), Positives = 64/139 (46%), Gaps = 1/139 (0%)
Query: 171 STTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKR 230
S++S+S+S + +SS E + K +K + KRK K S ++SDS+ + S
Sbjct: 261 SSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHE 320
Query: 231 RAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSDL 290
+ +K K + + K + S++ K S S K+S+ +P K ++ +E S
Sbjct: 321 ELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTH-KHSPEKRGSERKEGSSR 379
Query: 291 IGPEAPKTLTSQDDKPLNY 309
++ S+ P +Y
Sbjct: 380 SHGREERSRRSRSRSPGSY 398
Score = 43.5 bits (101), Expect = 4e-04
Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 15/178 (8%)
Query: 121 EREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSD-EHTPVEDEEPKKSTTSA---S 176
++ S +K S + S + E +S+ + ++ ++ KK+ S S
Sbjct: 246 QKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNS 305
Query: 177 TSEE---EKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAK 233
SEE KK+K S R+K K + K+ S DS+ SD D K R
Sbjct: 306 DSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKH---ESSREDSKWSHSDSDKKSRTH 362
Query: 234 K---AKKKEKKKKHRSKKY-KKKRSKKSRKESSDS-SSKESQEEFLENPWKDRTKAEE 286
K K+ ++K+ S+ + +++RS++SR S S +E+++ NP +++++ +
Sbjct: 363 KHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRND 420
Score = 40.8 bits (94), Expect = 0.002
Identities = 39/212 (18%), Positives = 90/212 (42%), Gaps = 8/212 (3%)
Query: 68 RNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESL- 126
R + +SRS+ ++ S+ +S+SSS S S+ + K+R+++
Sbjct: 240 RKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKC 299
Query: 127 ---RQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKK 183
E+++ + E S N E ++ ++ E ++ + S S+ +KK
Sbjct: 300 SGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDS-KWSHSDSDKK 358
Query: 184 KKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKK 243
++ + + +K+ S R H + S S S + ++RA++ +E+ ++
Sbjct: 359 SRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRR 418
Query: 244 HRSKKYKK---KRSKKSRKESSDSSSKESQEE 272
+ S+ + + K R+ + +K +Q E
Sbjct: 419 NDSRSHGTDLYRGEKMYREHPGGTHTKVTQRE 450
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 62.8 bits (151), Expect = 6e-10
Identities = 76/303 (25%), Positives = 126/303 (41%), Gaps = 32/303 (10%)
Query: 5 SGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRN---------G 55
S S S S S RSSS+S + RS R RSRS S SRS R+ G
Sbjct: 380 SSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRG 439
Query: 56 LTHQLGGLSQG---SRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDK 112
H GG G SR+ + R R R R + G + + + S SR S
Sbjct: 440 RRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSR---SRS 496
Query: 113 PWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHT-----PVEDEE 167
W L R SL + R SP +P P ++ T P E+
Sbjct: 497 SWS--LSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSP-SPSPAREKLTRPAASPAVGEK 553
Query: 168 PKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSK--RKHKKYSEDSDSDSDSETDSSD 225
KK T A+ E K +E+ K R +K ++ + KK +++ + E +
Sbjct: 554 LKK-TEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQERE 612
Query: 226 EDNKRRAKKAKKKEKKKKHRSK-KYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKA 284
++ + A+K + KE++++ + + +++++ S++SR S S E+ + + R+++
Sbjct: 613 DELRAMARKIRMKERERREKEREEWERQYSRQSR-----SPSPRYSREYSSSRRRSRSRS 667
Query: 285 EEP 287
P
Sbjct: 668 RSP 670
Score = 30.8 bits (68), Expect = 2.4
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 6/83 (7%)
Query: 164 EDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDS 223
+D+E ++ A EEEK S R R +RR+ + + + +K S S + DS T
Sbjct: 241 KDKEEAEAIKHAKALEEEKAMYSGRRSRR--QRREFREKRLRGRKISPPSYARRDSPT-- 296
Query: 224 SDEDNKRRAKKAKKKEKKKKHRS 246
D +R+ E + + RS
Sbjct: 297 --YDPYKRSPSESSSESRSRSRS 317
Score = 30.4 bits (67), Expect = 3.1
Identities = 25/112 (22%), Positives = 43/112 (38%), Gaps = 12/112 (10%)
Query: 165 DEEPKKSTTSASTSEEEKKKKSSRSKE------RSKKRRKKKSSKRKHKKYSEDSDSDSD 218
DEE + +A+ S K + + R+ R++ SS S S S S
Sbjct: 336 DEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSS 395
Query: 219 SETDSSDE------DNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDS 264
S + S + R A+ + + + RS++Y + RS+ R S
Sbjct: 396 SRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGS 447
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.303 0.121 0.328
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,302,868
Number of Sequences: 37866
Number of extensions: 942648
Number of successful extensions: 36243
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1081
Number of HSP's successfully gapped in prelim test: 1183
Number of HSP's that attempted gapping in prelim test: 8937
Number of HSP's gapped (non-prelim): 12321
length of query: 415
length of database: 18,247,518
effective HSP length: 105
effective length of query: 310
effective length of database: 14,271,588
effective search space: 4424192280
effective search space used: 4424192280
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.