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Search of human proteins with 167466198
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167466198 intercellular adhesion molecule 1 precursor [Homo
sapiens]
(532 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167466198 intercellular adhesion molecule 1 precursor [Homo s... 1074 0.0
gi|167466207 intercellular adhesion molecule 3 precursor [Homo s... 462 e-130
gi|189571583 intercellular adhesion molecule 5 precursor [Homo s... 430 e-120
gi|153082722 intercellular adhesion molecule 2 precursor [Homo s... 102 9e-22
gi|153082719 intercellular adhesion molecule 2 precursor [Homo s... 102 9e-22
gi|153082699 intercellular adhesion molecule 2 precursor [Homo s... 102 9e-22
gi|153082686 intercellular adhesion molecule 2 precursor [Homo s... 102 9e-22
gi|153082696 intercellular adhesion molecule 2 precursor [Homo s... 102 9e-22
gi|18201909 vascular cell adhesion molecule 1 isoform b precurso... 61 3e-09
gi|4504561 intercellular adhesion molecule 4 isoform 1 precursor... 54 4e-07
gi|12545402 intercellular adhesion molecule 4 isoform 2 precurso... 54 4e-07
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 50 7e-06
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 50 7e-06
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 50 7e-06
gi|61742797 basal cell adhesion molecule isoform 2 precursor [Ho... 47 6e-05
gi|31543106 basal cell adhesion molecule isoform 1 precursor [Ho... 47 6e-05
gi|4507875 vascular cell adhesion molecule 1 isoform a precursor... 46 1e-04
gi|118572606 hemicentin 1 [Homo sapiens] 45 1e-04
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 45 1e-04
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 45 1e-04
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens] 45 1e-04
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens] 45 1e-04
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 45 2e-04
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 45 2e-04
gi|11225258 myelin associated glycoprotein isoform a precursor [... 45 2e-04
gi|18104957 myelin associated glycoprotein isoform b precursor [... 45 2e-04
gi|4758822 nephrin precursor [Homo sapiens] 44 5e-04
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens] 43 8e-04
gi|157168355 CD22 molecule [Homo sapiens] 42 0.001
gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens] 42 0.001
>gi|167466198 intercellular adhesion molecule 1 precursor [Homo
sapiens]
Length = 532
Score = 1074 bits (2777), Expect = 0.0
Identities = 532/532 (100%), Positives = 532/532 (100%)
Query: 1 MAPSSPRPALPALLVLLGALFPGPGNAQTSVSPSKVILPRGGSVLVTCSTSCDQPKLLGI 60
MAPSSPRPALPALLVLLGALFPGPGNAQTSVSPSKVILPRGGSVLVTCSTSCDQPKLLGI
Sbjct: 1 MAPSSPRPALPALLVLLGALFPGPGNAQTSVSPSKVILPRGGSVLVTCSTSCDQPKLLGI 60
Query: 61 ETPLPKKELLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAP 120
ETPLPKKELLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAP
Sbjct: 61 ETPLPKKELLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAP 120
Query: 121 LPSWQPVGKNLTLRCQVEGGAPRANLTVVLLRGEKELKREPAVGEPAEVTTTVLVRRDHH 180
LPSWQPVGKNLTLRCQVEGGAPRANLTVVLLRGEKELKREPAVGEPAEVTTTVLVRRDHH
Sbjct: 121 LPSWQPVGKNLTLRCQVEGGAPRANLTVVLLRGEKELKREPAVGEPAEVTTTVLVRRDHH 180
Query: 181 GANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVSPRVLEVDTQGTVVCSLD 240
GANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVSPRVLEVDTQGTVVCSLD
Sbjct: 181 GANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVSPRVLEVDTQGTVVCSLD 240
Query: 241 GLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLTCAVILGNQSQE 300
GLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLTCAVILGNQSQE
Sbjct: 241 GLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLTCAVILGNQSQE 300
Query: 301 TLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTLNGVPAQPLGPRAQLLLKA 360
TLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTLNGVPAQPLGPRAQLLLKA
Sbjct: 301 TLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTLNGVPAQPLGPRAQLLLKA 360
Query: 361 TPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQ 420
TPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQ
Sbjct: 361 TPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQ 420
Query: 421 AWGNPLPELKCLKDGTFPLPIGESVTVTRDLEGTYLCRARSTQGEVTRKVTVNVLSPRYE 480
AWGNPLPELKCLKDGTFPLPIGESVTVTRDLEGTYLCRARSTQGEVTRKVTVNVLSPRYE
Sbjct: 421 AWGNPLPELKCLKDGTFPLPIGESVTVTRDLEGTYLCRARSTQGEVTRKVTVNVLSPRYE 480
Query: 481 IVIITVVAAAVIMGTAGLSTYLYNRQRKIKKYRLQQAQKGTPMKPNTQATPP 532
IVIITVVAAAVIMGTAGLSTYLYNRQRKIKKYRLQQAQKGTPMKPNTQATPP
Sbjct: 481 IVIITVVAAAVIMGTAGLSTYLYNRQRKIKKYRLQQAQKGTPMKPNTQATPP 532
>gi|167466207 intercellular adhesion molecule 3 precursor [Homo
sapiens]
Length = 547
Score = 462 bits (1189), Expect = e-130
Identities = 249/532 (46%), Positives = 334/532 (62%), Gaps = 14/532 (2%)
Query: 1 MAPSSPRPALPALLVLLGALFPGPGNAQ--TSVSPSKVILPRGGSVLVTCSTSCDQPKLL 58
M PS P L++ L PG + V P +L GGS+ V CST C + +
Sbjct: 4 MVPSVLWPRACWTLLVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSSEKI 63
Query: 59 GIETPLPKKELLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVEL 118
+ET L KEL+ G + LSNV +S+ +C C Q T + +TVY PERVEL
Sbjct: 64 ALETSL-SKELVASGMGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERVEL 122
Query: 119 APLPSWQPVGKNLTLRCQVEGGAPRANLTVVLLRGEKELKREPAVGEPAEVTTTVLVRRD 178
APLP WQPVG+N TLRCQVE G+PR +LTVVLLR E+EL R+PAV EPAEVT TVL RD
Sbjct: 123 APLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEPAEVTATVLASRD 182
Query: 179 HHGANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVSPRVLEVDTQGTVVCS 238
HGA FSCRTELD++PQGL LF NTSAP QL+TFVLP TPP+LV+PR LEV+T V C+
Sbjct: 183 DHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVDCT 242
Query: 239 LDGLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLTCAVILGNQS 298
LDGLFP SEAQV+LALGDQ LN TV D+ +A A+ + A+ EG + + C V LG +
Sbjct: 243 LDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGGER 302
Query: 299 QETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTLNGVPAQPLGPRAQLLL 358
+E + +T++SF P V L++P EG+ VTV C A R +VTL+GVPA G AQL L
Sbjct: 303 REARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQLQL 362
Query: 359 KATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPM 418
AT D+GRSF CSATLEV G+ +H+N + +LRVLYGP++D CP + W + ++
Sbjct: 363 NATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQ 422
Query: 419 CQAWGNPLPELKCLKDGTF-PLPIGESVTVTRDLEGTYLCRARSTQGEVTRKVTVNV--- 474
CQA GNP PEL+CLK+G+ +P+G V GTY C+A S++G+ T V +++
Sbjct: 423 CQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHNGTYQCQASSSRGKYTLVVVMDIEAG 482
Query: 475 ---LSPRYEIVIITVVAAAVIMGTAGLSTYLYNRQRKIKKYRLQQAQKGTPM 523
P + V++T+ +++ Y++ ++ Y +++ P+
Sbjct: 483 SSHFVPVFVAVLLTLGVVTIVLAL----MYVFREHQRSGSYHVREESTYLPL 530
>gi|189571583 intercellular adhesion molecule 5 precursor [Homo
sapiens]
Length = 924
Score = 430 bits (1106), Expect = e-120
Identities = 227/451 (50%), Positives = 299/451 (66%), Gaps = 8/451 (1%)
Query: 31 VSPSKVILPRGGSVLVTCSTSCDQPKLLGIETPLPKKELLLPGNNRKVYELSNVQE-DSQ 89
+ P + RGGS+ + CST+C +P+ G+ET L ++ G +L +++E ++Q
Sbjct: 38 LQPRVAFVERGGSLWLNCSTNCPRPERGGLETSL-RRNGTQRGLRWLARQLVDIREPETQ 96
Query: 90 PMCYSNCPDGQSTAKTFLTVYWTPERVELAPLPSWQPVGKNLTLRCQVEGGAPRANLTVV 149
P+C+ C A+ + + P+RVEL PLP WQPVG+N TL C+V G PRA+LT+
Sbjct: 97 PVCFFRCARRTLQARGLIRTFQRPDRVELMPLPPWQPVGENFTLSCRVPGAGPRASLTLT 156
Query: 150 LLRGEKELKREPAVGEP-----AEVTTTVLVRRDHHGANFSCRTELDLRPQGLELFENTS 204
LLRG +EL R GEP A +T TVL RR+ HGANFSCR ELDLRP GL LFEN+S
Sbjct: 157 LLRGAQELIRRSFAGEPPRARGAVLTATVLARREDHGANFSCRAELDLRPHGLGLFENSS 216
Query: 205 APYQLQTFVLPATPPQLVSPRVLEVDTQGTVVCSLDGLFPVSEAQVHLALGDQRLNPTVT 264
AP +L+TF L P+L +PR+LEV ++ V C+LDGLFP SEA+V+LALGDQ L+P VT
Sbjct: 217 APRELRTFSLSPDAPRLAAPRLLEVGSERPVSCTLDGLFPASEARVYLALGDQNLSPDVT 276
Query: 265 YGNDSFSAKASVSVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSE 324
D+F A A+ + +AE EG ++L C V LG +++ET + VTIYSFPAP + L++P VSE
Sbjct: 277 LEGDAFVATATATASAEQEGARQLVCNVTLGGENRETRENVTIYSFPAPLLTLSEPSVSE 336
Query: 325 GTEVTVKCEAHPRAKVTLNGVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEVAGQLIHK 384
G VTV C A +A VTL GVPA G AQL L AT D+ RSF C ATL+V G+ + K
Sbjct: 337 GQMVTVTCAAGAQALVTLEGVPAAVPGQPAQLQLNATENDDRRSFFCDATLDVDGETLIK 396
Query: 385 NQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLK-DGTFPLPIGE 443
N++ ELRVLY PRLD+ DCP +WTWPE +QT C+A GNP P + C + DG L +G
Sbjct: 397 NRSAELRVLYAPRLDDSDCPRSWTWPEGPEQTLRCEARGNPEPSVHCARSDGGAVLALGL 456
Query: 444 SVTVTRDLEGTYLCRARSTQGEVTRKVTVNV 474
VTR L GTY C+A + QGE + VT+ V
Sbjct: 457 LGPVTRALSGTYRCKAANDQGEAVKDVTLTV 487
Score = 79.7 bits (195), Expect = 6e-15
Identities = 96/390 (24%), Positives = 149/390 (38%), Gaps = 33/390 (8%)
Query: 98 DGQSTAKTFLTVYWTPERVELAPLPSWQPVGKNLTLRCQVEGGAPRANLTVVLLRGEKEL 157
+ S + T +P+ LA P VG + C ++G P + V L G++ L
Sbjct: 213 ENSSAPRELRTFSLSPDAPRLAA-PRLLEVGSERPVSCTLDGLFPASEARVYLALGDQNL 271
Query: 158 KREPAV-GEPAEVTTTVLVRRDHHGAN-FSCRTELDLRPQGLELFENTSAPYQLQTFVLP 215
+ + G+ T T + GA C L EN + + P
Sbjct: 272 SPDVTLEGDAFVATATATASAEQEGARQLVCNVTLG--------GENRETRENVTIYSFP 323
Query: 216 ATPPQLVSPRVLEVDTQGTVVCSLDGLFPVSEAQVHLALGDQ----RLNPTVTYGNDSFS 271
A L P V E TV C+ V+ V A+ Q +LN T SF
Sbjct: 324 APLLTLSEPSVSE-GQMVTVTCAAGAQALVTLEGVPAAVPGQPAQLQLNATENDDRRSFF 382
Query: 272 AKASVSVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVK 331
A++ V E R +L + +++P EG E T++
Sbjct: 383 CDATLDVDGETLIKNRSAELRVLYAPRLDDSDCPRSWTWP------------EGPEQTLR 430
Query: 332 CEAHPRAKVTLNGVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELR 391
CEA + +++ + A LL ++ C A + G+ + K+ T L
Sbjct: 431 CEARGNPEPSVHCARSDGGAVLALGLLGPVTRALSGTYRCKAAND-QGEAV-KDVT--LT 486
Query: 392 VLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESVTVTRDL 451
V Y P LD CP TW E ++ + C A G P P++ C++ G I + V R+
Sbjct: 487 VEYAPALDSVGCPERITWLEGTEASLSCVAHGVPPPDVICVRSGELGAVIEGLLRVAREH 546
Query: 452 EGTYLCRARSTQGEVTRKVTVNV-LSPRYE 480
GTY C A + +G + V V V PR+E
Sbjct: 547 AGTYRCEATNPRGSAAKNVAVTVEYGPRFE 576
Score = 79.7 bits (195), Expect = 6e-15
Identities = 87/331 (26%), Positives = 130/331 (39%), Gaps = 45/331 (13%)
Query: 164 GEPAEVTTTVLVRRDHHGANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVS 223
G+PA++ D +F C LD+ G L +N SA ++ L +
Sbjct: 363 GQPAQLQLNATENDDRR--SFFCDATLDV--DGETLIKNRSAELRV-----------LYA 407
Query: 224 PRVLEVDTQGTVVCSLDGLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASVS----VT 279
PR+ + D C +P Q P+V A ++ VT
Sbjct: 408 PRLDDSD------CPRSWTWPEGPEQTLRCEARGNPEPSVHCARSDGGAVLALGLLGPVT 461
Query: 280 AEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVS--EGTEVTVKCEAHPR 337
GT R A G ++ T+T+ PA + + ++ EGTE ++ C AH
Sbjct: 462 RALSGTYRCKAANDQGEAVKDV--TLTVEYAPALDSVGCPERITWLEGTEASLSCVAHGV 519
Query: 338 AKVTLNGVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPR 397
+ V + LG + LL+ E G ++ C AT + T E YGPR
Sbjct: 520 PPPDVICVRSGELGAVIEGLLRVAREHAG-TYRCEATNPRGSAAKNVAVTVE----YGPR 574
Query: 398 LDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDG----------TFPLPIGESVTV 447
+E CP NWTW E S + C+ G P P +KC+ G P P + +
Sbjct: 575 FEEPSCPSNWTWVEGSGRLFSCEVDGKPQPSVKCVGSGGATEGVLLPLAPPDPSPRAPRI 634
Query: 448 TRDL-EGTYLCRARSTQGEVTRKVTVNVLSP 477
R L G Y+C A + G V + V V+ SP
Sbjct: 635 PRVLAPGIYVCNATNRHGSVAKTVVVSAESP 665
Score = 57.4 bits (137), Expect = 3e-08
Identities = 33/95 (34%), Positives = 51/95 (53%), Gaps = 7/95 (7%)
Query: 396 PRLDERDCPGNWTWPENSQQTPM-CQAWGNPLPELKCLKDGTFPLPIGESVTVTRDLEGT 454
P +DE CP + TW E ++ + + C A G P P ++C ++G +P E V+R+ GT
Sbjct: 666 PEMDESTCPSHQTWLEGAEASALACAARGRPSPGVRCSREG---IPWPEQQRVSREDAGT 722
Query: 455 YLCRARSTQGEVTRKVTVNVLSPRYEIVIITVVAA 489
Y C A + G +R VTV V Y V+ + A+
Sbjct: 723 YHCVATNAHGTDSRTVTVGV---EYRPVVAELAAS 754
Score = 35.4 bits (80), Expect = 0.13
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Query: 453 GTYLCRARSTQGEVTRKVTVNVLSPRYEIVIITVV-AAAVIMGTAGLSTYLYNRQRKIKK 511
G Y C A + G R++TV V P + + AA++ AGL+ Y+ + K +
Sbjct: 810 GEYECAATNAHGRHARRITVRVAGPWLWVAVGGAAGGAALLAAGAGLAFYVQSTACKKGE 869
Query: 512 YRLQQAQ 518
Y +Q+A+
Sbjct: 870 YNVQEAE 876
>gi|153082722 intercellular adhesion molecule 2 precursor [Homo
sapiens]
Length = 275
Score = 102 bits (254), Expect = 9e-22
Identities = 75/220 (34%), Positives = 108/220 (49%), Gaps = 13/220 (5%)
Query: 13 LLVLLGALFPGPGNAQ----TSVSPSKVILPRGGSVLVTCSTSCDQPKLLGIETPLPKKE 68
L V L L PG+ + V P K+ + GS+ V CST+C+QP++ G+ET L K
Sbjct: 9 LTVALFTLICCPGSDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKI- 67
Query: 69 LLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAPLPSWQPVG 128
LL K Y +SN+ D+ C+ C Q + + ++VY P +V L P+ VG
Sbjct: 68 LLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVG 127
Query: 129 KNLTLRCQVEGGAPRANLTVVLLRGEKEL------KREPAVGEPAEVTTTVLVRRDHHGA 182
K+ T+ C+V P +LT+ L RG + L K PA E + R D H
Sbjct: 128 KSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGH-R 186
Query: 183 NFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLV 222
NFSC LDL +G +F SAP L+ + P + Q+V
Sbjct: 187 NFSCLAVLDLMSRGGNIFHKHSAPKMLEIYE-PVSDSQMV 225
Score = 34.3 bits (77), Expect = 0.29
Identities = 32/136 (23%), Positives = 52/136 (38%), Gaps = 23/136 (16%)
Query: 288 LTCAVILGNQSQETLQTVTIYSFPAPNVILTKPE-VSEGTEVTVKCEA---HPRAKVTL- 342
L C + + V++Y P ++ +P V+ G T++C P +TL
Sbjct: 89 LQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLF 148
Query: 343 --------------NGVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEV---AGQLIHKN 385
PA P A A ED R+FSC A L++ G + HK+
Sbjct: 149 LFRGNETLHYETFGKAAPA-PQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKH 207
Query: 386 QTRELRVLYGPRLDER 401
++ +Y P D +
Sbjct: 208 SAPKMLEIYEPVSDSQ 223
>gi|153082719 intercellular adhesion molecule 2 precursor [Homo
sapiens]
Length = 275
Score = 102 bits (254), Expect = 9e-22
Identities = 75/220 (34%), Positives = 108/220 (49%), Gaps = 13/220 (5%)
Query: 13 LLVLLGALFPGPGNAQ----TSVSPSKVILPRGGSVLVTCSTSCDQPKLLGIETPLPKKE 68
L V L L PG+ + V P K+ + GS+ V CST+C+QP++ G+ET L K
Sbjct: 9 LTVALFTLICCPGSDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKI- 67
Query: 69 LLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAPLPSWQPVG 128
LL K Y +SN+ D+ C+ C Q + + ++VY P +V L P+ VG
Sbjct: 68 LLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVG 127
Query: 129 KNLTLRCQVEGGAPRANLTVVLLRGEKEL------KREPAVGEPAEVTTTVLVRRDHHGA 182
K+ T+ C+V P +LT+ L RG + L K PA E + R D H
Sbjct: 128 KSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGH-R 186
Query: 183 NFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLV 222
NFSC LDL +G +F SAP L+ + P + Q+V
Sbjct: 187 NFSCLAVLDLMSRGGNIFHKHSAPKMLEIYE-PVSDSQMV 225
Score = 34.3 bits (77), Expect = 0.29
Identities = 32/136 (23%), Positives = 52/136 (38%), Gaps = 23/136 (16%)
Query: 288 LTCAVILGNQSQETLQTVTIYSFPAPNVILTKPE-VSEGTEVTVKCEA---HPRAKVTL- 342
L C + + V++Y P ++ +P V+ G T++C P +TL
Sbjct: 89 LQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLF 148
Query: 343 --------------NGVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEV---AGQLIHKN 385
PA P A A ED R+FSC A L++ G + HK+
Sbjct: 149 LFRGNETLHYETFGKAAPA-PQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKH 207
Query: 386 QTRELRVLYGPRLDER 401
++ +Y P D +
Sbjct: 208 SAPKMLEIYEPVSDSQ 223
>gi|153082699 intercellular adhesion molecule 2 precursor [Homo
sapiens]
Length = 275
Score = 102 bits (254), Expect = 9e-22
Identities = 75/220 (34%), Positives = 108/220 (49%), Gaps = 13/220 (5%)
Query: 13 LLVLLGALFPGPGNAQ----TSVSPSKVILPRGGSVLVTCSTSCDQPKLLGIETPLPKKE 68
L V L L PG+ + V P K+ + GS+ V CST+C+QP++ G+ET L K
Sbjct: 9 LTVALFTLICCPGSDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKI- 67
Query: 69 LLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAPLPSWQPVG 128
LL K Y +SN+ D+ C+ C Q + + ++VY P +V L P+ VG
Sbjct: 68 LLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVG 127
Query: 129 KNLTLRCQVEGGAPRANLTVVLLRGEKEL------KREPAVGEPAEVTTTVLVRRDHHGA 182
K+ T+ C+V P +LT+ L RG + L K PA E + R D H
Sbjct: 128 KSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGH-R 186
Query: 183 NFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLV 222
NFSC LDL +G +F SAP L+ + P + Q+V
Sbjct: 187 NFSCLAVLDLMSRGGNIFHKHSAPKMLEIYE-PVSDSQMV 225
Score = 34.3 bits (77), Expect = 0.29
Identities = 32/136 (23%), Positives = 52/136 (38%), Gaps = 23/136 (16%)
Query: 288 LTCAVILGNQSQETLQTVTIYSFPAPNVILTKPE-VSEGTEVTVKCEA---HPRAKVTL- 342
L C + + V++Y P ++ +P V+ G T++C P +TL
Sbjct: 89 LQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLF 148
Query: 343 --------------NGVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEV---AGQLIHKN 385
PA P A A ED R+FSC A L++ G + HK+
Sbjct: 149 LFRGNETLHYETFGKAAPA-PQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKH 207
Query: 386 QTRELRVLYGPRLDER 401
++ +Y P D +
Sbjct: 208 SAPKMLEIYEPVSDSQ 223
>gi|153082686 intercellular adhesion molecule 2 precursor [Homo
sapiens]
Length = 275
Score = 102 bits (254), Expect = 9e-22
Identities = 75/220 (34%), Positives = 108/220 (49%), Gaps = 13/220 (5%)
Query: 13 LLVLLGALFPGPGNAQ----TSVSPSKVILPRGGSVLVTCSTSCDQPKLLGIETPLPKKE 68
L V L L PG+ + V P K+ + GS+ V CST+C+QP++ G+ET L K
Sbjct: 9 LTVALFTLICCPGSDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKI- 67
Query: 69 LLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAPLPSWQPVG 128
LL K Y +SN+ D+ C+ C Q + + ++VY P +V L P+ VG
Sbjct: 68 LLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVG 127
Query: 129 KNLTLRCQVEGGAPRANLTVVLLRGEKEL------KREPAVGEPAEVTTTVLVRRDHHGA 182
K+ T+ C+V P +LT+ L RG + L K PA E + R D H
Sbjct: 128 KSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGH-R 186
Query: 183 NFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLV 222
NFSC LDL +G +F SAP L+ + P + Q+V
Sbjct: 187 NFSCLAVLDLMSRGGNIFHKHSAPKMLEIYE-PVSDSQMV 225
Score = 34.3 bits (77), Expect = 0.29
Identities = 32/136 (23%), Positives = 52/136 (38%), Gaps = 23/136 (16%)
Query: 288 LTCAVILGNQSQETLQTVTIYSFPAPNVILTKPE-VSEGTEVTVKCEA---HPRAKVTL- 342
L C + + V++Y P ++ +P V+ G T++C P +TL
Sbjct: 89 LQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLF 148
Query: 343 --------------NGVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEV---AGQLIHKN 385
PA P A A ED R+FSC A L++ G + HK+
Sbjct: 149 LFRGNETLHYETFGKAAPA-PQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKH 207
Query: 386 QTRELRVLYGPRLDER 401
++ +Y P D +
Sbjct: 208 SAPKMLEIYEPVSDSQ 223
>gi|153082696 intercellular adhesion molecule 2 precursor [Homo
sapiens]
Length = 275
Score = 102 bits (254), Expect = 9e-22
Identities = 75/220 (34%), Positives = 108/220 (49%), Gaps = 13/220 (5%)
Query: 13 LLVLLGALFPGPGNAQ----TSVSPSKVILPRGGSVLVTCSTSCDQPKLLGIETPLPKKE 68
L V L L PG+ + V P K+ + GS+ V CST+C+QP++ G+ET L K
Sbjct: 9 LTVALFTLICCPGSDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKI- 67
Query: 69 LLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAPLPSWQPVG 128
LL K Y +SN+ D+ C+ C Q + + ++VY P +V L P+ VG
Sbjct: 68 LLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVG 127
Query: 129 KNLTLRCQVEGGAPRANLTVVLLRGEKEL------KREPAVGEPAEVTTTVLVRRDHHGA 182
K+ T+ C+V P +LT+ L RG + L K PA E + R D H
Sbjct: 128 KSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGH-R 186
Query: 183 NFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLV 222
NFSC LDL +G +F SAP L+ + P + Q+V
Sbjct: 187 NFSCLAVLDLMSRGGNIFHKHSAPKMLEIYE-PVSDSQMV 225
Score = 34.3 bits (77), Expect = 0.29
Identities = 32/136 (23%), Positives = 52/136 (38%), Gaps = 23/136 (16%)
Query: 288 LTCAVILGNQSQETLQTVTIYSFPAPNVILTKPE-VSEGTEVTVKCEA---HPRAKVTL- 342
L C + + V++Y P ++ +P V+ G T++C P +TL
Sbjct: 89 LQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLF 148
Query: 343 --------------NGVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEV---AGQLIHKN 385
PA P A A ED R+FSC A L++ G + HK+
Sbjct: 149 LFRGNETLHYETFGKAAPA-PQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKH 207
Query: 386 QTRELRVLYGPRLDER 401
++ +Y P D +
Sbjct: 208 SAPKMLEIYEPVSDSQ 223
>gi|18201909 vascular cell adhesion molecule 1 isoform b precursor
[Homo sapiens]
Length = 647
Score = 60.8 bits (146), Expect = 3e-09
Identities = 110/509 (21%), Positives = 198/509 (38%), Gaps = 64/509 (12%)
Query: 13 LLVLLGA------LFPGPGNAQTSVSP-SKVILPRGGSVLVTCSTS-CDQPKL---LGIE 61
++V+LGA +F + +P S+ + G SV +TCST+ C+ P I+
Sbjct: 5 MVVILGASNILWIMFAASQAFKIETTPESRYLAQIGDSVSLTCSTTGCESPFFSWRTQID 64
Query: 62 TPLPKKELLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAPL 121
+PL K + + + +C + C + + +Y P+ E+ L
Sbjct: 65 SPLNGKVTNEGTTSTLTMNPVSFGNEHSYLCTATCESRKLEKGIQVEIYSFPKDPEIH-L 123
Query: 122 PSWQPVGKNLTLRCQVEGGAPRANLTVVLLRGEKELK---------REPAVGEPAEVTTT 172
GK +T++C V P L + LL+G+ +K R+ + EVT T
Sbjct: 124 SGPLEAGKPITVKCSVADVYPFDRLEIDLLKGDHLMKSQEFLEDADRKSLETKSLEVTFT 183
Query: 173 VLVRRDHHGANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVSPRV-LEVDT 231
++ + G CR +L + + A +LQ ++ P V+P L+
Sbjct: 184 PVI--EDIGKVLVCRAKLHIDEMD-SVPTVRQAVKELQVYISPKNTVISVNPSTKLQEGG 240
Query: 232 QGTVVCSLDGLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLTCA 291
T+ CS +GL P E L + L GN + + +++ ED G
Sbjct: 241 SVTMTCSSEGL-PAPEIFWSKKLDNGNLQH--LSGNATLTL---IAMRMEDSGIYVCEGV 294
Query: 292 VILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCE---AHPRAKVTLNGVPAQ 348
++G +E + + +FP I + G+ VTV C+ +P ++ + + +
Sbjct: 295 NLIGKNRKEV--ELIVQAFPRDPEIEMSGGLVNGSSVTVSCKVPSVYPLDRLEIELLKGE 352
Query: 349 PLGPRAQLL----LKA------------TPEDNGRSFSCSATLEVAGQLIHKNQTRELRV 392
+ + L +K+ T ED G++ C A L + Q + +
Sbjct: 353 TILENIEFLEDTDMKSLENKSLEMTFIPTIEDTGKALVCQAKLHIDDMEFEPKQRQSTQT 412
Query: 393 LY---GPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPEL---KCLKDGTFPLPIGESVT 446
LY PR + E S C + G P P++ + L +G P+ E+ T
Sbjct: 413 LYVNVAPRDTTVLVSPSSILEEGSSVNMTCLSQGFPAPKILWSRQLPNGELQ-PLSENAT 471
Query: 447 VT-----RDLEGTYLCRARSTQGEVTRKV 470
+T + G YLC + G ++V
Sbjct: 472 LTLISTKMEDSGVYLCEGINQAGRSRKEV 500
Score = 35.8 bits (81), Expect = 0.10
Identities = 66/296 (22%), Positives = 117/296 (39%), Gaps = 41/296 (13%)
Query: 210 QTFVLPATPPQLVSPRVLEVDTQGTVVCSLDGL-FPVSEAQVHLALGDQRLNPTVTYGND 268
Q F + TP S + ++ ++ CS G P + + D LN VT N+
Sbjct: 23 QAFKIETTPE---SRYLAQIGDSVSLTCSTTGCESPFFSWRTQI---DSPLNGKVT--NE 74
Query: 269 SFSAKASVSVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPA-PNVILTKPEVSEGTE 327
++ +++ + L A + ++ +Q V IYSFP P + L+ P + G
Sbjct: 75 GTTSTLTMNPVSFGNEHSYLCTATCESRKLEKGIQ-VEIYSFPKDPEIHLSGP-LEAGKP 132
Query: 328 VTVKC---EAHPRAKVTLNGVPAQPLGPRAQLLLKA--------------TP--EDNGRS 368
+TVKC + +P ++ ++ + L + L A TP ED G+
Sbjct: 133 ITVKCSVADVYPFDRLEIDLLKGDHLMKSQEFLEDADRKSLETKSLEVTFTPVIEDIGKV 192
Query: 369 FSCSATL---EVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNP 425
C A L E+ + +EL+V P+ + E T C + G P
Sbjct: 193 LVCRAKLHIDEMDSVPTVRQAVKELQVYISPKNTVISVNPSTKLQEGGSVTMTCSSEGLP 252
Query: 426 LPEL---KCLKDGTFPLPIGES----VTVTRDLEGTYLCRARSTQGEVTRKVTVNV 474
PE+ K L +G G + + + + G Y+C + G+ ++V + V
Sbjct: 253 APEIFWSKKLDNGNLQHLSGNATLTLIAMRMEDSGIYVCEGVNLIGKNRKEVELIV 308
>gi|4504561 intercellular adhesion molecule 4 isoform 1 precursor
[Homo sapiens]
Length = 271
Score = 53.9 bits (128), Expect = 4e-07
Identities = 55/177 (31%), Positives = 72/177 (40%), Gaps = 34/177 (19%)
Query: 12 ALLVLLGALFPGPGNAQ-------------------TSV------SPSKVILPRGGSVLV 46
+LL L A +PG G+A TSV SP V + G SV +
Sbjct: 8 SLLFFLAAAYPGVGSALGRRTKRAQSPKGSPLAPSGTSVPFWVRMSPEFVAVQPGKSVQL 67
Query: 47 TCSTSCDQPKLLGIETPLPKKELLLPGNNRKVYELSNVQE-DSQPMCYSNCPDGQSTAKT 105
CS SC QP+ + TPL ++ L G Y+L +V+ S C C A +
Sbjct: 68 NCSNSCPQPQNSSLRTPL-RQGKTLRGPGWVSYQLLDVRAWSSLAHCLVTCAGKTRWATS 126
Query: 106 FLTVYWTPERVELAPLPSWQPV--GKNLTLRCQVEGGAPRANLTVVLLRGEKELKRE 160
+T Y P V L P PV G+ TLRC V P L V L G + + E
Sbjct: 127 RITAYKPPHSVILEP-----PVLKGRKYTLRCHVTQVFPVGYLVVTLRHGSRVIYSE 178
>gi|12545402 intercellular adhesion molecule 4 isoform 2 precursor
[Homo sapiens]
Length = 237
Score = 53.9 bits (128), Expect = 4e-07
Identities = 55/177 (31%), Positives = 72/177 (40%), Gaps = 34/177 (19%)
Query: 12 ALLVLLGALFPGPGNAQ-------------------TSV------SPSKVILPRGGSVLV 46
+LL L A +PG G+A TSV SP V + G SV +
Sbjct: 8 SLLFFLAAAYPGVGSALGRRTKRAQSPKGSPLAPSGTSVPFWVRMSPEFVAVQPGKSVQL 67
Query: 47 TCSTSCDQPKLLGIETPLPKKELLLPGNNRKVYELSNVQE-DSQPMCYSNCPDGQSTAKT 105
CS SC QP+ + TPL ++ L G Y+L +V+ S C C A +
Sbjct: 68 NCSNSCPQPQNSSLRTPL-RQGKTLRGPGWVSYQLLDVRAWSSLAHCLVTCAGKTRWATS 126
Query: 106 FLTVYWTPERVELAPLPSWQPV--GKNLTLRCQVEGGAPRANLTVVLLRGEKELKRE 160
+T Y P V L P PV G+ TLRC V P L V L G + + E
Sbjct: 127 RITAYKPPHSVILEP-----PVLKGRKYTLRCHVTQVFPVGYLVVTLRHGSRVIYSE 178
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 49.7 bits (117), Expect = 7e-06
Identities = 63/220 (28%), Positives = 93/220 (42%), Gaps = 31/220 (14%)
Query: 283 EGTQRLTCAVILGNQSQETLQTVTIY-SFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVT 341
EGT C+ ++GN SQ+ V + P T+ V + T++C A + T
Sbjct: 1039 EGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPT 1098
Query: 342 LNGV-PAQPLGPRAQLLL----------KATPEDNGRSFSCSATLEVAGQLIHKNQTREL 390
+ QP+G L L +A GR +SC A +AG+ K EL
Sbjct: 1099 VTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGR-YSCVAE-NLAGRAERKF---EL 1153
Query: 391 RVLYGPRL-DERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGES----- 444
VL P L + D N T +S T +C+A G P P ++ + G P+ GE
Sbjct: 1154 SVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFR-GEEPVSPGEDTYLLA 1212
Query: 445 ------VTVTRDLE-GTYLCRARSTQGEVTRKVTVNVLSP 477
+T T++ + G Y C A + GE R +V VL P
Sbjct: 1213 GGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVP 1252
Score = 46.2 bits (108), Expect = 7e-05
Identities = 43/166 (25%), Positives = 65/166 (39%), Gaps = 14/166 (8%)
Query: 322 VSEGTEVTVKCEAH----PRAKVTLNGVP--AQPLGPRAQLLLKATPEDNGRSFSCSATL 375
V G+ V + CEA P +G P +Q L L L+A + ++SC A
Sbjct: 2227 VVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVS 2286
Query: 376 EVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDG 435
E H +L V+ P +++ P + + +C A G P P + KDG
Sbjct: 2287 EAGEARRHF----QLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDG 2342
Query: 436 TFPLPIGESVTVTRDLE----GTYLCRARSTQGEVTRKVTVNVLSP 477
+ + TR L G Y C A S G + + V V +P
Sbjct: 2343 QALTRLENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAP 2388
Score = 43.1 bits (100), Expect = 6e-04
Identities = 75/313 (23%), Positives = 119/313 (38%), Gaps = 60/313 (19%)
Query: 202 NTSAPYQLQTFVLPATPPQLVSPRVLEVDTQGTVVCSLDGLFPVSEAQVHLALGDQRLNP 261
N+S QL+ V PPQ+ PR E TQ +VV DG+ + + P
Sbjct: 1052 NSSQDLQLEVHV----PPQIAGPR--EPPTQVSVV--QDGVATLE------CNATGKPPP 1097
Query: 262 TVTYGNDSFSAKASVSVTAEDEG------------TQRLTCAVILGNQSQETLQTVTIYS 309
TVT+ D A + + +++G T R +C + N + + +
Sbjct: 1098 TVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSC--VAENLAGRAERKFELSV 1155
Query: 310 FPAPNVI-----LTKPEVSEGTEVTVKCEAH----PRAKVTLNGVPAQP------LGPRA 354
P +I LT + + +T+ CEA P + P P L
Sbjct: 1156 LVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGW 1215
Query: 355 QLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQ 414
L + T E + +SC A+ E AG+ + + VL P ++ D +
Sbjct: 1216 MLKMTQTQEQDSGLYSCLASNE-AGEA---RRNFSVEVLVPPSIENEDLEEVIKVLDGQT 1271
Query: 415 QTPMCQAWGNPLPELKCLKDGTFPLPIGESVTVTRD------------LEGTYLCRARST 462
MC G+P P+L KDG PL G++ ++ D G Y C A +
Sbjct: 1272 AHLMCNVTGHPQPKLTWFKDGR-PLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANA 1330
Query: 463 QGEVTRKVTVNVL 475
GE T+ ++VL
Sbjct: 1331 VGEKTKHFQLSVL 1343
Score = 42.4 bits (98), Expect = 0.001
Identities = 59/189 (31%), Positives = 82/189 (43%), Gaps = 38/189 (20%)
Query: 311 PAPNVILTKPEVSEGTEVTVKCEAH--PRAKVT--------LNGVPAQPLGPRAQL-LLK 359
P P+V+ E EV + CEA PR +T GV Q L P QL +
Sbjct: 2761 PLPSVVRAVAE----EEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVL-PGGQLRIAH 2815
Query: 360 ATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMC 419
A+PED G ++ C A AG + K + V+ P + E P T E S C
Sbjct: 2816 ASPEDAG-NYLCIAK-NSAGSAMGKTRL----VVQVPPVIENGLPDLST-TEGSHAFLPC 2868
Query: 420 QAWGNPLPELKCLKDGT--------FPL-PIGESVTVTRDLEG----TYLCRARSTQGEV 466
+A G+P P + KDG F + P GE + ++LEG TY C A + G
Sbjct: 2869 KARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE--LLVKNLEGQDAGTYTCTAENAVGRA 2926
Query: 467 TRKVTVNVL 475
R+V + +L
Sbjct: 2927 RRRVHLTIL 2935
Score = 42.0 bits (97), Expect = 0.001
Identities = 58/215 (26%), Positives = 81/215 (37%), Gaps = 23/215 (10%)
Query: 300 ETLQTVTIYSFPAPNVILTKPEVSE-----GTEVTVKCEAH----PRAKVTLNGVPAQPL 350
E T +S PAP +L E G +V ++C P+ + T + P P
Sbjct: 202 EQFPTPHAFSPPAPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPG 261
Query: 351 GPRAQL-----LLKATPE---DNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERD 402
GP Q+ +L+ T D GR + C A AGQ Q LRV P + +
Sbjct: 262 GPHLQVQEDGQVLRITGSHVGDEGR-YQCVA-FSPAGQQARDFQ---LRVHAPPTIWGSN 316
Query: 403 CPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESVTVTRDLEGTYLCRARST 462
G E+ +C+A G P P + KDG LP V TR L RA+S+
Sbjct: 317 ETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGAL-LPTSTKVVYTRGGRQLQLGRAQSS 375
Query: 463 QGEVTRKVTVNVLSPRYEIVIITVVAAAVIMGTAG 497
V N + + + V I G G
Sbjct: 376 DAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGG 410
Score = 36.6 bits (83), Expect = 0.059
Identities = 70/264 (26%), Positives = 99/264 (37%), Gaps = 36/264 (13%)
Query: 234 TVVCSLDGLFPVSEAQVHLALGDQRLNPTVTYGNDS--FSAKASVSVTAEDEGTQRLTCA 291
TV DG V + G QRL +D +S K S +V E T LT
Sbjct: 1872 TVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVS-NVAGEAVRTFTLTVQ 1930
Query: 292 V--ILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTLNGVPAQP 349
V N ET+ V +P V+ VT + P ++GV ++
Sbjct: 1931 VPPTFENPKTETVSQVA----GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSR- 1985
Query: 350 LGPRAQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTW 409
G R QL + P G +++C A A + + VL PR+
Sbjct: 1986 -GGRLQLS-RLQPAQAG-TYTCVAENTQA----EARKDFVVAVLVAPRIRSSGVAREHHV 2038
Query: 410 PENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESV------------TVTRDLE----G 453
E + C+A G P P++ LKDG+ P+G+ + V + L G
Sbjct: 2039 LEGQEVRLDCEADGQPPPDVAWLKDGS---PLGQDMGPHLRFYLDGGSLVLKGLRASDAG 2095
Query: 454 TYLCRARSTQGEVTRKVTVNVLSP 477
Y C A + GE R TVNVL P
Sbjct: 2096 AYTCVAHNPAGEDARLHTVNVLVP 2119
Score = 35.4 bits (80), Expect = 0.13
Identities = 33/128 (25%), Positives = 52/128 (40%), Gaps = 19/128 (14%)
Query: 364 DNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRL--DERDCPGNWTWPENSQQTPMCQA 421
+N +SC A+ EV +H EL VL P + D + T +S + C A
Sbjct: 1623 ENAGRYSCKASNEVGEDWLHY----ELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPA 1678
Query: 422 WGNPLPELKCLKDGTFPLPIGESVTVTRDLE------------GTYLCRARSTQGEVTRK 469
GNP+P + L++G P + V D + +Y+C A + G +
Sbjct: 1679 LGNPVPTISWLQNG-LPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKL 1737
Query: 470 VTVNVLSP 477
T+ V P
Sbjct: 1738 FTLRVQVP 1745
Score = 35.0 bits (79), Expect = 0.17
Identities = 40/144 (27%), Positives = 59/144 (40%), Gaps = 23/144 (15%)
Query: 351 GPRAQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWP 410
G +L A ED G+ ++C T E+ G+ + + + VL P + + D G
Sbjct: 1402 GTHGLQILNAQKEDAGQ-YTCVVTNEL-GEAV---KNYHVEVLIPPSISKDDPLGEVGVK 1456
Query: 411 E-----NSQQTPMCQAWGNPLPELKCLKDGTFPLP------IGE------SVTVTRDLEG 453
E NS T C++W P P ++ KDG P +GE T D G
Sbjct: 1457 EVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSD-SG 1515
Query: 454 TYLCRARSTQGEVTRKVTVNVLSP 477
YLC A + GE + V + P
Sbjct: 1516 RYLCVATNVAGEDDQDFNVLIQVP 1539
Score = 35.0 bits (79), Expect = 0.17
Identities = 60/216 (27%), Positives = 89/216 (41%), Gaps = 52/216 (24%)
Query: 288 LTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTL----N 343
LT VILG+ ++E ++ VT V+ + V+++C A T+ N
Sbjct: 1648 LTPPVILGD-TEELVEEVT---------------VNASSTVSLQCPALGNPVPTISWLQN 1691
Query: 344 GVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEVAG----QLIHKNQTRE------LRVL 393
G+P P PR Q+L ++G+ S T EVA + +NQ LRV
Sbjct: 1692 GLPFSP-SPRLQVL------EDGQVLQVS-TAEVADAASYMCVAENQAGSAEKLFTLRVQ 1743
Query: 394 YGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESVTV---TRD 450
PR+ D T NS + C +P PE+ KD L +GE V + T
Sbjct: 1744 VPPRIAGLDLE-QVTAILNSSVSLPCDVHAHPNPEVTWYKDSQ-ALSLGEEVFLLPGTHT 1801
Query: 451 LE---------GTYLCRARSTQGEVTRKVTVNVLSP 477
L+ G Y C A + G + V ++VL P
Sbjct: 1802 LQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVP 1837
Score = 33.9 bits (76), Expect = 0.38
Identities = 77/309 (24%), Positives = 116/309 (37%), Gaps = 50/309 (16%)
Query: 202 NTSAPYQLQTFVLP--ATPPQLVSPRVLEVDTQGTVVCSLDGLFPVSEAQVHLALGDQRL 259
+T Y L+ V P PP L P + V+T + C+ G S + L G+ +
Sbjct: 773 STELRYGLRVNVPPRITLPPSLPGPVL--VNTPVRLTCNATGA--PSPTLMWLKDGNP-V 827
Query: 260 NPTVTYGNDSFSAKASV---SVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVI 316
+P T G F + S A D G R +C + + E Q V + P+++
Sbjct: 828 SPAGTPGLQVFPGGRVLTLASARASDSG--RYSCVAV--SAVGEDRQDVVLQVHMPPSIL 883
Query: 317 LTKPEVS--EGTEVTVKCEAHPRAKVTLNG-VPAQPLGPRAQLLLKATPE---------- 363
+ VS V ++C++H L+ +PL PR + L A
Sbjct: 884 GEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVW 943
Query: 364 DNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWG 423
D G ++C A + H N L V P R+ T E + C+ G
Sbjct: 944 DAGH-YTCEALNQAGRSEKHYN----LNVWVAPVFPLRESH-TLTVREGHPTSLSCECRG 997
Query: 424 NPLPELKCLKDGTFPLPIGESV------TVTRDL---------EGTYLCRARSTQGEVTR 468
P P++ KDG PLP GE V R L EGTY C + G ++
Sbjct: 998 VPFPKISWRKDGQ-PLP-GEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQ 1055
Query: 469 KVTVNVLSP 477
+ + V P
Sbjct: 1056 DLQLEVHVP 1064
Score = 32.7 bits (73), Expect = 0.85
Identities = 30/103 (29%), Positives = 45/103 (43%), Gaps = 7/103 (6%)
Query: 342 LNGVPAQPLGPRAQLLLKA-TPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDE 400
L+G P + L L + +P D+G + C AT EV ++ +L V P + E
Sbjct: 45 LHGQPGVAVLEEGSLFLASVSPADSG-DYECQATNEVGST----SRRAKLVVYVPPSIRE 99
Query: 401 RDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTF-PLPIG 442
N + T C A G P+PE+ LKD +P+G
Sbjct: 100 DGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLG 142
Score = 32.3 bits (72), Expect = 1.1
Identities = 43/170 (25%), Positives = 65/170 (38%), Gaps = 20/170 (11%)
Query: 277 SVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAH- 335
+++ D G T G+ S V I++ P VS + C+A
Sbjct: 2450 ALSTADSGDYSCTARNAAGSTS--VAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADG 2507
Query: 336 ---PRAKVTLNGVPAQPLGPRAQLL----LKATP---EDNGRSFSCSATLEVAGQLIHKN 385
P + VP P PR ++L L+ P +D G + C A+
Sbjct: 2508 VPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGH-YLCLASNSAGSD----R 2562
Query: 386 QTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDG 435
Q R+LRVL P + P N T ++ C+A G+P P + KDG
Sbjct: 2563 QGRDLRVLEPPAI--APSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDG 2610
Score = 31.6 bits (70), Expect = 1.9
Identities = 69/263 (26%), Positives = 99/263 (37%), Gaps = 51/263 (19%)
Query: 244 PVSEAQ-VHLALGDQRLNPTVTYGNDS--FSAKASVSVTAEDEGTQRLTCAVILGNQSQE 300
PVS + +L G L T T DS +S AS + G R N S E
Sbjct: 1201 PVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLAS-----NEAGEARR-------NFSVE 1248
Query: 301 TLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEA--HPRAKVTL--NGVP-----AQPLG 351
L +I + VI +V +G + C HP+ K+T +G P A +
Sbjct: 1249 VLVPPSIENEDLEEVI----KVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHIS 1304
Query: 352 PRAQLL--LKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRL---DERDCPGN 406
P LL L+A G +SC A V K + +L VL P + E
Sbjct: 1305 PDGVLLQVLQANLSSAGH-YSCIAANAVG----EKTKHFQLSVLLAPTILGGAEDSADEE 1359
Query: 407 WTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESVTV---TRDLE---------GT 454
T N+ + +C+A P P + +KDG P ++ + T L+ G
Sbjct: 1360 VTVTVNNPISLICEALAFPSPNITWMKDGA-PFEASRNIQLLPGTHGLQILNAQKEDAGQ 1418
Query: 455 YLCRARSTQGEVTRKVTVNVLSP 477
Y C + GE + V VL P
Sbjct: 1419 YTCVVTNELGEAVKNYHVEVLIP 1441
Score = 30.0 bits (66), Expect = 5.5
Identities = 54/223 (24%), Positives = 84/223 (37%), Gaps = 38/223 (17%)
Query: 277 SVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAH- 335
++ +D GT T +G + T+ + P + + G + ++C A
Sbjct: 2906 NLEGQDAGTYTCTAENAVGRARRRVHLTILV--LPVFTTLPGDRSLRLGDRLWLRCAARG 2963
Query: 336 ---PRAKVTLN------GVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEVAG-QLIHKN 385
PR T+N GV Q G Q + ED+G ++ C A V Q +
Sbjct: 2964 SPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAA-VSREDSG-TYVCWAENRVGRTQAVSFV 3021
Query: 386 QTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPI---- 441
+E VL G P C G+P+P++ +KDG LP+
Sbjct: 3022 HVKEAPVLQGEAFSYL------VEPVGGSIQLDCVVRGDPVPDIHWIKDG---LPLRGSH 3072
Query: 442 ------GESVTV---TRDLEGTYLCRARSTQGEVTRKVTVNVL 475
S+T+ RD G Y C A + G V +KV + VL
Sbjct: 3073 LRHQLQNGSLTIHRTERDDAGRYQCLAENEMG-VAKKVVILVL 3114
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 49.7 bits (117), Expect = 7e-06
Identities = 63/220 (28%), Positives = 93/220 (42%), Gaps = 31/220 (14%)
Query: 283 EGTQRLTCAVILGNQSQETLQTVTIY-SFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVT 341
EGT C+ ++GN SQ+ V + P T+ V + T++C A + T
Sbjct: 2230 EGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPT 2289
Query: 342 LNGV-PAQPLGPRAQLLL----------KATPEDNGRSFSCSATLEVAGQLIHKNQTREL 390
+ QP+G L L +A GR +SC A +AG+ K EL
Sbjct: 2290 VTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGR-YSCVAE-NLAGRAERKF---EL 2344
Query: 391 RVLYGPRL-DERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGES----- 444
VL P L + D N T +S T +C+A G P P ++ + G P+ GE
Sbjct: 2345 SVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFR-GEEPVSPGEDTYLLA 2403
Query: 445 ------VTVTRDLE-GTYLCRARSTQGEVTRKVTVNVLSP 477
+T T++ + G Y C A + GE R +V VL P
Sbjct: 2404 GGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVP 2443
Score = 46.2 bits (108), Expect = 7e-05
Identities = 43/166 (25%), Positives = 65/166 (39%), Gaps = 14/166 (8%)
Query: 322 VSEGTEVTVKCEAH----PRAKVTLNGVP--AQPLGPRAQLLLKATPEDNGRSFSCSATL 375
V G+ V + CEA P +G P +Q L L L+A + ++SC A
Sbjct: 3418 VVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVS 3477
Query: 376 EVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDG 435
E H +L V+ P +++ P + + +C A G P P + KDG
Sbjct: 3478 EAGEARRHF----QLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDG 3533
Query: 436 TFPLPIGESVTVTRDLE----GTYLCRARSTQGEVTRKVTVNVLSP 477
+ + TR L G Y C A S G + + V V +P
Sbjct: 3534 QALTRLENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAP 3579
Score = 43.1 bits (100), Expect = 6e-04
Identities = 75/313 (23%), Positives = 119/313 (38%), Gaps = 60/313 (19%)
Query: 202 NTSAPYQLQTFVLPATPPQLVSPRVLEVDTQGTVVCSLDGLFPVSEAQVHLALGDQRLNP 261
N+S QL+ V PPQ+ PR E TQ +VV DG+ + + P
Sbjct: 2243 NSSQDLQLEVHV----PPQIAGPR--EPPTQVSVV--QDGVATLE------CNATGKPPP 2288
Query: 262 TVTYGNDSFSAKASVSVTAEDEG------------TQRLTCAVILGNQSQETLQTVTIYS 309
TVT+ D A + + +++G T R +C + N + + +
Sbjct: 2289 TVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSC--VAENLAGRAERKFELSV 2346
Query: 310 FPAPNVI-----LTKPEVSEGTEVTVKCEAH----PRAKVTLNGVPAQP------LGPRA 354
P +I LT + + +T+ CEA P + P P L
Sbjct: 2347 LVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGW 2406
Query: 355 QLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQ 414
L + T E + +SC A+ E AG+ + + VL P ++ D +
Sbjct: 2407 MLKMTQTQEQDSGLYSCLASNE-AGEA---RRNFSVEVLVPPSIENEDLEEVIKVLDGQT 2462
Query: 415 QTPMCQAWGNPLPELKCLKDGTFPLPIGESVTVTRD------------LEGTYLCRARST 462
MC G+P P+L KDG PL G++ ++ D G Y C A +
Sbjct: 2463 AHLMCNVTGHPQPKLTWFKDGR-PLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANA 2521
Query: 463 QGEVTRKVTVNVL 475
GE T+ ++VL
Sbjct: 2522 VGEKTKHFQLSVL 2534
Score = 42.4 bits (98), Expect = 0.001
Identities = 59/189 (31%), Positives = 82/189 (43%), Gaps = 38/189 (20%)
Query: 311 PAPNVILTKPEVSEGTEVTVKCEAH--PRAKVT--------LNGVPAQPLGPRAQL-LLK 359
P P+V+ E EV + CEA PR +T GV Q L P QL +
Sbjct: 3952 PLPSVVRAVAE----EEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVL-PGGQLRIAH 4006
Query: 360 ATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMC 419
A+PED G ++ C A AG + K + V+ P + E P T E S C
Sbjct: 4007 ASPEDAG-NYLCIAK-NSAGSAMGKTRL----VVQVPPVIENGLPDLST-TEGSHAFLPC 4059
Query: 420 QAWGNPLPELKCLKDGT--------FPL-PIGESVTVTRDLEG----TYLCRARSTQGEV 466
+A G+P P + KDG F + P GE + ++LEG TY C A + G
Sbjct: 4060 KARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE--LLVKNLEGQDAGTYTCTAENAVGRA 4117
Query: 467 TRKVTVNVL 475
R+V + +L
Sbjct: 4118 RRRVHLTIL 4126
Score = 40.4 bits (93), Expect = 0.004
Identities = 56/216 (25%), Positives = 82/216 (37%), Gaps = 46/216 (21%)
Query: 325 GTEVTVKCEAH--PRAKVT---------LNGVPAQPLGPRAQLLLKA-TPEDNGRSFSCS 372
G ++ C A P+ +VT L+G P + L L + +P D+G + C
Sbjct: 1221 GENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSG-DYECQ 1279
Query: 373 ATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCL 432
AT EV ++ +L V P + E N + T C A G P+PE+ L
Sbjct: 1280 ATNEVGST----SRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWL 1335
Query: 433 KD-----------------------GTFPLPIGESVTVTRDLE---GTYLCRARSTQGEV 466
KD G L G+S+ R E G Y CRA + G
Sbjct: 1336 KDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTA 1395
Query: 467 TRKVTVNVLSPRYEIVIITVVAAAVIMGTAGLSTYL 502
R + VL+P ++ AA ++G AG L
Sbjct: 1396 QRDFHLLVLTPP---SVLGAGAAQEVLGLAGADVEL 1428
Score = 38.1 bits (87), Expect = 0.020
Identities = 50/185 (27%), Positives = 71/185 (38%), Gaps = 18/185 (9%)
Query: 325 GTEVTVKCEAH----PRAKVTLNGVPAQPLGPRAQL-----LLKATPE---DNGRSFSCS 372
G +V ++C P+ + T + P P GP Q+ +L+ T D GR + C
Sbjct: 1423 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGR-YQCV 1481
Query: 373 ATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCL 432
A AGQ Q LRV P + + G E+ +C+A G P P +
Sbjct: 1482 A-FSPAGQQARDFQ---LRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWF 1537
Query: 433 KDGTFPLPIGESVTVTRDLEGTYLCRARSTQGEVTRKVTVNVLSPRYEIVIITVVAAAVI 492
KDG LP V TR L RA+S+ V N + + + V I
Sbjct: 1538 KDGAL-LPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTI 1596
Query: 493 MGTAG 497
G G
Sbjct: 1597 EGAGG 1601
Score = 36.6 bits (83), Expect = 0.059
Identities = 70/264 (26%), Positives = 99/264 (37%), Gaps = 36/264 (13%)
Query: 234 TVVCSLDGLFPVSEAQVHLALGDQRLNPTVTYGNDS--FSAKASVSVTAEDEGTQRLTCA 291
TV DG V + G QRL +D +S K S +V E T LT
Sbjct: 3063 TVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVS-NVAGEAVRTFTLTVQ 3121
Query: 292 V--ILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTLNGVPAQP 349
V N ET+ V +P V+ VT + P ++GV ++
Sbjct: 3122 VPPTFENPKTETVSQVA----GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSR- 3176
Query: 350 LGPRAQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTW 409
G R QL + P G +++C A A + + VL PR+
Sbjct: 3177 -GGRLQLS-RLQPAQAG-TYTCVAENTQA----EARKDFVVAVLVAPRIRSSGVAREHHV 3229
Query: 410 PENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESV------------TVTRDLE----G 453
E + C+A G P P++ LKDG+ P+G+ + V + L G
Sbjct: 3230 LEGQEVRLDCEADGQPPPDVAWLKDGS---PLGQDMGPHLRFYLDGGSLVLKGLRASDAG 3286
Query: 454 TYLCRARSTQGEVTRKVTVNVLSP 477
Y C A + GE R TVNVL P
Sbjct: 3287 AYTCVAHNPAGEDARLHTVNVLVP 3310
Score = 36.2 bits (82), Expect = 0.077
Identities = 76/304 (25%), Positives = 114/304 (37%), Gaps = 40/304 (13%)
Query: 202 NTSAPYQLQTFVLP--ATPPQLVSPRVLEVDTQGTVVCSLDGLFPVSEAQVHLALGDQRL 259
+T Y L+ V P PP L P + V+T + C+ G S + L G+ +
Sbjct: 1964 STELRYGLRVNVPPRITLPPSLPGPVL--VNTPVRLTCNATGA--PSPTLMWLKDGNP-V 2018
Query: 260 NPTVTYGNDSFSAKASV---SVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVI 316
+P T G F + S A D G R +C + + E Q V + P+++
Sbjct: 2019 SPAGTPGLQVFPGGRVLTLASARASDSG--RYSCVAV--SAVGEDRQDVVLQVHMPPSIL 2074
Query: 317 LTKPEVS--EGTEVTVKCEAHPRAKVTLNG-VPAQPLGPRAQLLLKATPE----DNGRSF 369
+ VS V ++C++H L+ +PL PR + L A D +
Sbjct: 2075 GEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVW 2134
Query: 370 SCSA-TLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPE 428
T E Q H + L V P R+ T E + C+ G P P+
Sbjct: 2135 DAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESH-TLTVREGHPTSLSCECRGVPFPK 2193
Query: 429 LKCLKDGTFPLPIGESV------TVTRDL---------EGTYLCRARSTQGEVTRKVTVN 473
+ KDG PLP GE V R L EGTY C + G ++ + +
Sbjct: 2194 ISWRKDGQ-PLP-GEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLE 2251
Query: 474 VLSP 477
V P
Sbjct: 2252 VHVP 2255
Score = 35.4 bits (80), Expect = 0.13
Identities = 33/128 (25%), Positives = 52/128 (40%), Gaps = 19/128 (14%)
Query: 364 DNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRL--DERDCPGNWTWPENSQQTPMCQA 421
+N +SC A+ EV +H EL VL P + D + T +S + C A
Sbjct: 2814 ENAGRYSCKASNEVGEDWLHY----ELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPA 2869
Query: 422 WGNPLPELKCLKDGTFPLPIGESVTVTRDLE------------GTYLCRARSTQGEVTRK 469
GNP+P + L++G P + V D + +Y+C A + G +
Sbjct: 2870 LGNPVPTISWLQNG-LPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKL 2928
Query: 470 VTVNVLSP 477
T+ V P
Sbjct: 2929 FTLRVQVP 2936
Score = 35.0 bits (79), Expect = 0.17
Identities = 40/144 (27%), Positives = 59/144 (40%), Gaps = 23/144 (15%)
Query: 351 GPRAQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWP 410
G +L A ED G+ ++C T E+ G+ + + + VL P + + D G
Sbjct: 2593 GTHGLQILNAQKEDAGQ-YTCVVTNEL-GEAV---KNYHVEVLIPPSISKDDPLGEVGVK 2647
Query: 411 E-----NSQQTPMCQAWGNPLPELKCLKDGTFPLP------IGE------SVTVTRDLEG 453
E NS T C++W P P ++ KDG P +GE T D G
Sbjct: 2648 EVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSD-SG 2706
Query: 454 TYLCRARSTQGEVTRKVTVNVLSP 477
YLC A + GE + V + P
Sbjct: 2707 RYLCVATNVAGEDDQDFNVLIQVP 2730
Score = 35.0 bits (79), Expect = 0.17
Identities = 60/216 (27%), Positives = 89/216 (41%), Gaps = 52/216 (24%)
Query: 288 LTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTL----N 343
LT VILG+ ++E ++ VT V+ + V+++C A T+ N
Sbjct: 2839 LTPPVILGD-TEELVEEVT---------------VNASSTVSLQCPALGNPVPTISWLQN 2882
Query: 344 GVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEVAG----QLIHKNQTRE------LRVL 393
G+P P PR Q+L ++G+ S T EVA + +NQ LRV
Sbjct: 2883 GLPFSP-SPRLQVL------EDGQVLQVS-TAEVADAASYMCVAENQAGSAEKLFTLRVQ 2934
Query: 394 YGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESVTV---TRD 450
PR+ D T NS + C +P PE+ KD L +GE V + T
Sbjct: 2935 VPPRIAGLDLE-QVTAILNSSVSLPCDVHAHPNPEVTWYKDSQ-ALSLGEEVFLLPGTHT 2992
Query: 451 LE---------GTYLCRARSTQGEVTRKVTVNVLSP 477
L+ G Y C A + G + V ++VL P
Sbjct: 2993 LQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVP 3028
Score = 32.7 bits (73), Expect = 0.85
Identities = 95/449 (21%), Positives = 155/449 (34%), Gaps = 70/449 (15%)
Query: 70 LLPGNNRKVYELSNVQ---------EDSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAP 120
+LP + +V +L+++ + + C ++ +G + A +L V P+ V +
Sbjct: 556 VLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQ-VSIHT 614
Query: 121 LPSWQPVGKNLTLRCQVEGGAPRANLTVVLLRGEKELKREPAVGEPAEVTTTVLVRRDHH 180
G + + C G P +++ R + L+ + + A+ T +
Sbjct: 615 SSQHFSQGVEVKVSCSASG-YPTPHIS--WSRESQALQEDSRIHVDAQGTLIIQGVAPED 671
Query: 181 GANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVSPR----VLEVDTQGTVV 236
N+SC+ ++ +T L T P VS ++ V + +V
Sbjct: 672 AGNYSCQATNEVGTDQ-------------ETVTLYYTDPPSVSAVNAVVLVAVGEEAVLV 718
Query: 237 CSLDGLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAE-DEGTQRLTCAVILG 295
C G+ P L + L P S S K + E D GT LG
Sbjct: 719 CEASGVPPPRVIWYRGGL-EMILAP-----EGSSSGKLRIPAAQERDAGTYTCRAVNELG 772
Query: 296 NQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEA--HPRAKVTLNGVPAQPLGPR 353
+ S E + + P + V G + C A P VT QPLG R
Sbjct: 773 DASAEI--QLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLR 830
Query: 354 --------------AQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLD 399
L ++ ++ + C A V G++ + + R + + P
Sbjct: 831 LGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEAR-NVFGKV--QAEARLIVTGHAPPQI 887
Query: 400 ERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGE--------SVTVTRDL 451
P P G PLPE LKDG PLP G S+ + R L
Sbjct: 888 ASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGR-PLPPGSRHSIRADGSLHLDRAL 946
Query: 452 E---GTYLCRARSTQGEVTRKVTVNVLSP 477
+ G Y C A +T G R V + V P
Sbjct: 947 QEHAGRYSCVATNTAGSQHRDVELVVQVP 975
Score = 32.3 bits (72), Expect = 1.1
Identities = 43/170 (25%), Positives = 65/170 (38%), Gaps = 20/170 (11%)
Query: 277 SVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAH- 335
+++ D G T G+ S V I++ P VS + C+A
Sbjct: 3641 ALSTADSGDYSCTARNAAGSTS--VAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADG 3698
Query: 336 ---PRAKVTLNGVPAQPLGPRAQLL----LKATP---EDNGRSFSCSATLEVAGQLIHKN 385
P + VP P PR ++L L+ P +D G + C A+
Sbjct: 3699 VPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGH-YLCLASNSAGSD----R 3753
Query: 386 QTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDG 435
Q R+LRVL P + P N T ++ C+A G+P P + KDG
Sbjct: 3754 QGRDLRVLEPPAI--APSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDG 3801
Score = 31.6 bits (70), Expect = 1.9
Identities = 69/263 (26%), Positives = 99/263 (37%), Gaps = 51/263 (19%)
Query: 244 PVSEAQ-VHLALGDQRLNPTVTYGNDS--FSAKASVSVTAEDEGTQRLTCAVILGNQSQE 300
PVS + +L G L T T DS +S AS + G R N S E
Sbjct: 2392 PVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLAS-----NEAGEARR-------NFSVE 2439
Query: 301 TLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEA--HPRAKVTL--NGVP-----AQPLG 351
L +I + VI +V +G + C HP+ K+T +G P A +
Sbjct: 2440 VLVPPSIENEDLEEVI----KVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHIS 2495
Query: 352 PRAQLL--LKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRL---DERDCPGN 406
P LL L+A G +SC A V K + +L VL P + E
Sbjct: 2496 PDGVLLQVLQANLSSAGH-YSCIAANAVG----EKTKHFQLSVLLAPTILGGAEDSADEE 2550
Query: 407 WTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESVTV---TRDLE---------GT 454
T N+ + +C+A P P + +KDG P ++ + T L+ G
Sbjct: 2551 VTVTVNNPISLICEALAFPSPNITWMKDGA-PFEASRNIQLLPGTHGLQILNAQKEDAGQ 2609
Query: 455 YLCRARSTQGEVTRKVTVNVLSP 477
Y C + GE + V VL P
Sbjct: 2610 YTCVVTNELGEAVKNYHVEVLIP 2632
Score = 30.4 bits (67), Expect = 4.2
Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 7/65 (10%)
Query: 419 CQAWGNPLPELKCLKDGTFPLPIGESVTV------TRDLEGTYLCRARSTQGEVTRKVTV 472
C A GNP P+L KDG G +V T D G Y C A ++ G +V +
Sbjct: 1141 CVAEGNPEPQLSWSKDGVVLQGRGPQGSVHFAAIRTSD-AGRYRCEASNSAGVDAWEVEL 1199
Query: 473 NVLSP 477
VL P
Sbjct: 1200 RVLEP 1204
Score = 30.0 bits (66), Expect = 5.5
Identities = 54/223 (24%), Positives = 84/223 (37%), Gaps = 38/223 (17%)
Query: 277 SVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAH- 335
++ +D GT T +G + T+ + P + + G + ++C A
Sbjct: 4097 NLEGQDAGTYTCTAENAVGRARRRVHLTILV--LPVFTTLPGDRSLRLGDRLWLRCAARG 4154
Query: 336 ---PRAKVTLN------GVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEVAG-QLIHKN 385
PR T+N GV Q G Q + ED+G ++ C A V Q +
Sbjct: 4155 SPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAA-VSREDSG-TYVCWAENRVGRTQAVSFV 4212
Query: 386 QTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPI---- 441
+E VL G P C G+P+P++ +KDG LP+
Sbjct: 4213 HVKEAPVLQGEAFSYL------VEPVGGSIQLDCVVRGDPVPDIHWIKDG---LPLRGSH 4263
Query: 442 ------GESVTV---TRDLEGTYLCRARSTQGEVTRKVTVNVL 475
S+T+ RD G Y C A + G V +KV + VL
Sbjct: 4264 LRHQLQNGSLTIHRTERDDAGRYQCLAENEMG-VAKKVVILVL 4305
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 49.7 bits (117), Expect = 7e-06
Identities = 63/220 (28%), Positives = 93/220 (42%), Gaps = 31/220 (14%)
Query: 283 EGTQRLTCAVILGNQSQETLQTVTIY-SFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVT 341
EGT C+ ++GN SQ+ V + P T+ V + T++C A + T
Sbjct: 948 EGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPT 1007
Query: 342 LNGV-PAQPLGPRAQLLL----------KATPEDNGRSFSCSATLEVAGQLIHKNQTREL 390
+ QP+G L L +A GR +SC A +AG+ K EL
Sbjct: 1008 VTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGR-YSCVAE-NLAGRAERKF---EL 1062
Query: 391 RVLYGPRL-DERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGES----- 444
VL P L + D N T +S T +C+A G P P ++ + G P+ GE
Sbjct: 1063 SVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFR-GEEPVSPGEDTYLLA 1121
Query: 445 ------VTVTRDLE-GTYLCRARSTQGEVTRKVTVNVLSP 477
+T T++ + G Y C A + GE R +V VL P
Sbjct: 1122 GGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVP 1161
Score = 46.2 bits (108), Expect = 7e-05
Identities = 43/166 (25%), Positives = 65/166 (39%), Gaps = 14/166 (8%)
Query: 322 VSEGTEVTVKCEAH----PRAKVTLNGVP--AQPLGPRAQLLLKATPEDNGRSFSCSATL 375
V G+ V + CEA P +G P +Q L L L+A + ++SC A
Sbjct: 2136 VVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVS 2195
Query: 376 EVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDG 435
E H +L V+ P +++ P + + +C A G P P + KDG
Sbjct: 2196 EAGEARRHF----QLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDG 2251
Query: 436 TFPLPIGESVTVTRDLE----GTYLCRARSTQGEVTRKVTVNVLSP 477
+ + TR L G Y C A S G + + V V +P
Sbjct: 2252 QALTRLENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAP 2297
Score = 43.1 bits (100), Expect = 6e-04
Identities = 75/313 (23%), Positives = 119/313 (38%), Gaps = 60/313 (19%)
Query: 202 NTSAPYQLQTFVLPATPPQLVSPRVLEVDTQGTVVCSLDGLFPVSEAQVHLALGDQRLNP 261
N+S QL+ V PPQ+ PR E TQ +VV DG+ + + P
Sbjct: 961 NSSQDLQLEVHV----PPQIAGPR--EPPTQVSVV--QDGVATLE------CNATGKPPP 1006
Query: 262 TVTYGNDSFSAKASVSVTAEDEG------------TQRLTCAVILGNQSQETLQTVTIYS 309
TVT+ D A + + +++G T R +C + N + + +
Sbjct: 1007 TVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSC--VAENLAGRAERKFELSV 1064
Query: 310 FPAPNVI-----LTKPEVSEGTEVTVKCEAH----PRAKVTLNGVPAQP------LGPRA 354
P +I LT + + +T+ CEA P + P P L
Sbjct: 1065 LVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGW 1124
Query: 355 QLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQ 414
L + T E + +SC A+ E AG+ + + VL P ++ D +
Sbjct: 1125 MLKMTQTQEQDSGLYSCLASNE-AGEA---RRNFSVEVLVPPSIENEDLEEVIKVLDGQT 1180
Query: 415 QTPMCQAWGNPLPELKCLKDGTFPLPIGESVTVTRD------------LEGTYLCRARST 462
MC G+P P+L KDG PL G++ ++ D G Y C A +
Sbjct: 1181 AHLMCNVTGHPQPKLTWFKDGR-PLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANA 1239
Query: 463 QGEVTRKVTVNVL 475
GE T+ ++VL
Sbjct: 1240 VGEKTKHFQLSVL 1252
Score = 42.4 bits (98), Expect = 0.001
Identities = 59/189 (31%), Positives = 82/189 (43%), Gaps = 38/189 (20%)
Query: 311 PAPNVILTKPEVSEGTEVTVKCEAH--PRAKVT--------LNGVPAQPLGPRAQL-LLK 359
P P+V+ E EV + CEA PR +T GV Q L P QL +
Sbjct: 2670 PLPSVVRAVAE----EEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVL-PGGQLRIAH 2724
Query: 360 ATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMC 419
A+PED G ++ C A AG + K + V+ P + E P T E S C
Sbjct: 2725 ASPEDAG-NYLCIAK-NSAGSAMGKTRL----VVQVPPVIENGLPDLST-TEGSHAFLPC 2777
Query: 420 QAWGNPLPELKCLKDGT--------FPL-PIGESVTVTRDLEG----TYLCRARSTQGEV 466
+A G+P P + KDG F + P GE + ++LEG TY C A + G
Sbjct: 2778 KARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE--LLVKNLEGQDAGTYTCTAENAVGRA 2835
Query: 467 TRKVTVNVL 475
R+V + +L
Sbjct: 2836 RRRVHLTIL 2844
Score = 38.1 bits (87), Expect = 0.020
Identities = 50/185 (27%), Positives = 71/185 (38%), Gaps = 18/185 (9%)
Query: 325 GTEVTVKCEAH----PRAKVTLNGVPAQPLGPRAQL-----LLKATPE---DNGRSFSCS 372
G +V ++C P+ + T + P P GP Q+ +L+ T D GR + C
Sbjct: 141 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGR-YQCV 199
Query: 373 ATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCL 432
A AGQ Q LRV P + + G E+ +C+A G P P +
Sbjct: 200 A-FSPAGQQARDFQ---LRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWF 255
Query: 433 KDGTFPLPIGESVTVTRDLEGTYLCRARSTQGEVTRKVTVNVLSPRYEIVIITVVAAAVI 492
KDG LP V TR L RA+S+ V N + + + V I
Sbjct: 256 KDGAL-LPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTI 314
Query: 493 MGTAG 497
G G
Sbjct: 315 EGAGG 319
Score = 36.6 bits (83), Expect = 0.059
Identities = 70/264 (26%), Positives = 99/264 (37%), Gaps = 36/264 (13%)
Query: 234 TVVCSLDGLFPVSEAQVHLALGDQRLNPTVTYGNDS--FSAKASVSVTAEDEGTQRLTCA 291
TV DG V + G QRL +D +S K S +V E T LT
Sbjct: 1781 TVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVS-NVAGEAVRTFTLTVQ 1839
Query: 292 V--ILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTLNGVPAQP 349
V N ET+ V +P V+ VT + P ++GV ++
Sbjct: 1840 VPPTFENPKTETVSQVA----GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSR- 1894
Query: 350 LGPRAQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTW 409
G R QL + P G +++C A A + + VL PR+
Sbjct: 1895 -GGRLQLS-RLQPAQAG-TYTCVAENTQA----EARKDFVVAVLVAPRIRSSGVAREHHV 1947
Query: 410 PENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESV------------TVTRDLE----G 453
E + C+A G P P++ LKDG+ P+G+ + V + L G
Sbjct: 1948 LEGQEVRLDCEADGQPPPDVAWLKDGS---PLGQDMGPHLRFYLDGGSLVLKGLRASDAG 2004
Query: 454 TYLCRARSTQGEVTRKVTVNVLSP 477
Y C A + GE R TVNVL P
Sbjct: 2005 AYTCVAHNPAGEDARLHTVNVLVP 2028
Score = 35.4 bits (80), Expect = 0.13
Identities = 76/304 (25%), Positives = 113/304 (37%), Gaps = 40/304 (13%)
Query: 202 NTSAPYQLQTFVLP--ATPPQLVSPRVLEVDTQGTVVCSLDGLFPVSEAQVHLALGDQRL 259
+T Y L+ V P PP L P + V+T + C+ G S + L G+ +
Sbjct: 682 STELRYGLRVNVPPRITLPPSLPGPVL--VNTPVRLTCNATGA--PSPTLMWLKDGNP-V 736
Query: 260 NPTVTYGNDSFSAKASV---SVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVI 316
+P T G F + S A D G R +C + + E Q V + P+++
Sbjct: 737 SPAGTPGLQVFPGGRVLTLASARASDSG--RYSCVAV--SAVGEDRQDVVLQVHMPPSIL 792
Query: 317 LTKPEVS--EGTEVTVKCEAHPRAKVTLNG-VPAQPLGPRAQLLLKATPE----DNGRSF 369
+ VS V ++C++H L+ +PL PR + L A D +
Sbjct: 793 GEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVW 852
Query: 370 SCSA-TLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPE 428
T E Q H + L V P R+ T E C+ G P P+
Sbjct: 853 DAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESH-TLTVREGHPTRLSCECRGVPFPK 911
Query: 429 LKCLKDGTFPLPIGESV------TVTRDL---------EGTYLCRARSTQGEVTRKVTVN 473
+ KDG PLP GE V R L EGTY C + G ++ + +
Sbjct: 912 ISWRKDGQ-PLP-GEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLE 969
Query: 474 VLSP 477
V P
Sbjct: 970 VHVP 973
Score = 35.4 bits (80), Expect = 0.13
Identities = 33/128 (25%), Positives = 52/128 (40%), Gaps = 19/128 (14%)
Query: 364 DNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRL--DERDCPGNWTWPENSQQTPMCQA 421
+N +SC A+ EV +H EL VL P + D + T +S + C A
Sbjct: 1532 ENAGRYSCKASNEVGEDWLHY----ELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPA 1587
Query: 422 WGNPLPELKCLKDGTFPLPIGESVTVTRDLE------------GTYLCRARSTQGEVTRK 469
GNP+P + L++G P + V D + +Y+C A + G +
Sbjct: 1588 LGNPVPTISWLQNG-LPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKL 1646
Query: 470 VTVNVLSP 477
T+ V P
Sbjct: 1647 FTLRVQVP 1654
Score = 35.0 bits (79), Expect = 0.17
Identities = 60/216 (27%), Positives = 89/216 (41%), Gaps = 52/216 (24%)
Query: 288 LTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTL----N 343
LT VILG+ ++E ++ VT V+ + V+++C A T+ N
Sbjct: 1557 LTPPVILGD-TEELVEEVT---------------VNASSTVSLQCPALGNPVPTISWLQN 1600
Query: 344 GVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEVAG----QLIHKNQTRE------LRVL 393
G+P P PR Q+L ++G+ S T EVA + +NQ LRV
Sbjct: 1601 GLPFSP-SPRLQVL------EDGQVLQVS-TAEVADAASYMCVAENQAGSAEKLFTLRVQ 1652
Query: 394 YGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESVTV---TRD 450
PR+ D T NS + C +P PE+ KD L +GE V + T
Sbjct: 1653 VPPRIAGLDLE-QVTAILNSSVSLPCDVHAHPNPEVTWYKDSQ-ALSLGEEVFLLPGTHT 1710
Query: 451 LE---------GTYLCRARSTQGEVTRKVTVNVLSP 477
L+ G Y C A + G + V ++VL P
Sbjct: 1711 LQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVP 1746
Score = 32.7 bits (73), Expect = 0.85
Identities = 39/144 (27%), Positives = 58/144 (40%), Gaps = 23/144 (15%)
Query: 351 GPRAQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWP 410
G +L A ED G+ ++C T E+ G+ + + + VL P + + D
Sbjct: 1311 GTHGLQILNAQKEDAGQ-YTCVVTNEL-GEAV---KNYHVEVLIPPSISKDDPLAEVGVK 1365
Query: 411 E-----NSQQTPMCQAWGNPLPELKCLKDGTFPLP------IGE------SVTVTRDLEG 453
E NS T C++W P P ++ KDG P +GE T D G
Sbjct: 1366 EVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSD-SG 1424
Query: 454 TYLCRARSTQGEVTRKVTVNVLSP 477
YLC A + GE + V + P
Sbjct: 1425 RYLCVATNVAGEDDQDFNVLIQVP 1448
Score = 32.3 bits (72), Expect = 1.1
Identities = 43/170 (25%), Positives = 65/170 (38%), Gaps = 20/170 (11%)
Query: 277 SVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAH- 335
+++ D G T G+ S V I++ P VS + C+A
Sbjct: 2359 ALSTADSGDYSCTARNAAGSTS--VAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADG 2416
Query: 336 ---PRAKVTLNGVPAQPLGPRAQLL----LKATP---EDNGRSFSCSATLEVAGQLIHKN 385
P + VP P PR ++L L+ P +D G + C A+
Sbjct: 2417 VPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGH-YLCLASNSAGSD----R 2471
Query: 386 QTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDG 435
Q R+LRVL P + P N T ++ C+A G+P P + KDG
Sbjct: 2472 QGRDLRVLEPPAI--APSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDG 2519
Score = 31.6 bits (70), Expect = 1.9
Identities = 69/263 (26%), Positives = 99/263 (37%), Gaps = 51/263 (19%)
Query: 244 PVSEAQ-VHLALGDQRLNPTVTYGNDS--FSAKASVSVTAEDEGTQRLTCAVILGNQSQE 300
PVS + +L G L T T DS +S AS + G R N S E
Sbjct: 1110 PVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLAS-----NEAGEARR-------NFSVE 1157
Query: 301 TLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEA--HPRAKVTL--NGVP-----AQPLG 351
L +I + VI +V +G + C HP+ K+T +G P A +
Sbjct: 1158 VLVPPSIENEDLEEVI----KVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHIS 1213
Query: 352 PRAQLL--LKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRL---DERDCPGN 406
P LL L+A G +SC A V K + +L VL P + E
Sbjct: 1214 PDGVLLQVLQANLSSAGH-YSCIAANAVG----EKTKHFQLSVLLAPTILGGAEDSADEE 1268
Query: 407 WTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESVTV---TRDLE---------GT 454
T N+ + +C+A P P + +KDG P ++ + T L+ G
Sbjct: 1269 VTVTVNNPISLICEALAFPSPNITWMKDGA-PFEASRNIQLLPGTHGLQILNAQKEDAGQ 1327
Query: 455 YLCRARSTQGEVTRKVTVNVLSP 477
Y C + GE + V VL P
Sbjct: 1328 YTCVVTNELGEAVKNYHVEVLIP 1350
Score = 30.0 bits (66), Expect = 5.5
Identities = 54/223 (24%), Positives = 84/223 (37%), Gaps = 38/223 (17%)
Query: 277 SVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAH- 335
++ +D GT T +G + T+ + P + + G + ++C A
Sbjct: 2815 NLEGQDAGTYTCTAENAVGRARRRVHLTILV--LPVFTTLPGDRSLRLGDRLWLRCAARG 2872
Query: 336 ---PRAKVTLN------GVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEVAG-QLIHKN 385
PR T+N GV Q G Q + ED+G ++ C A V Q +
Sbjct: 2873 SPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAA-VSREDSG-TYVCWAENRVGRTQAVSFV 2930
Query: 386 QTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPI---- 441
+E VL G P C G+P+P++ +KDG LP+
Sbjct: 2931 HVKEAPVLQGEAFSYL------VEPVGGSIQLDCVVRGDPVPDIHWIKDG---LPLRGSH 2981
Query: 442 ------GESVTV---TRDLEGTYLCRARSTQGEVTRKVTVNVL 475
S+T+ RD G Y C A + G V +KV + VL
Sbjct: 2982 LRHQLQNGSLTIRRTERDDAGRYQCLAENEMG-VAKKVVILVL 3023
Score = 29.3 bits (64), Expect = 9.4
Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 29/133 (21%)
Query: 396 PRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKD--------------------- 434
P + E N + T C A G P+PE+ LKD
Sbjct: 17 PSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQ 76
Query: 435 --GTFPLPIGESVTVTRDLE---GTYLCRARSTQGEVTRKVTVNVLSPRYEIVIITVVAA 489
G L G+S+ R E G Y CRA + G R + VL+P ++ AA
Sbjct: 77 VGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPP---SVLGAGAA 133
Query: 490 AVIMGTAGLSTYL 502
++G AG L
Sbjct: 134 QEVLGLAGADVEL 146
>gi|61742797 basal cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 588
Score = 46.6 bits (109), Expect = 6e-05
Identities = 56/225 (24%), Positives = 95/225 (42%), Gaps = 24/225 (10%)
Query: 321 EVSEGTEVTVKCEAHPRAKVTLNGVP---------AQPLGPRAQLLLKATPEDNGRSFSC 371
E+SEG +++ + +++G+P + PLG L L + D+ ++ C
Sbjct: 365 ELSEGKVLSLPLNSSAVVNCSVHGLPTPALRWTKDSTPLGDGPMLSLSSITFDSNGTYVC 424
Query: 372 SATLEVAGQLIHKNQTRELRVLYGPRLD--ERDCPGNWTWPENSQQTPMCQAWGNPLPEL 429
A+L ++ + Q L V P L E + + +W E + T +C A G+P P+L
Sbjct: 425 EASLPTV-PVLSRTQNFTLLVQGSPELKTAEIEPKADGSWREGDEVTLICSARGHPDPKL 483
Query: 430 KCLKDG---TFPLP-----IGESVT--VTRDLEGTYL-CRARSTQGEVTRKVTVNVLSPR 478
+ G P+P + S+T VT L + C A + G +SP+
Sbjct: 484 SWSQLGGSPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEASNPHGNKRHVFHFGTVSPQ 543
Query: 479 YEIVIITVVAAAVIMGTAGL-STYLYNRQRKIKKYRLQQAQKGTP 522
+ V+A AV +G L Y +RK Q+ +KG P
Sbjct: 544 TSQAGVAVMAVAVSVGLLLLVVAVFYCVRRKGGPCCRQRREKGAP 588
>gi|31543106 basal cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 628
Score = 46.6 bits (109), Expect = 6e-05
Identities = 56/225 (24%), Positives = 95/225 (42%), Gaps = 24/225 (10%)
Query: 321 EVSEGTEVTVKCEAHPRAKVTLNGVP---------AQPLGPRAQLLLKATPEDNGRSFSC 371
E+SEG +++ + +++G+P + PLG L L + D+ ++ C
Sbjct: 365 ELSEGKVLSLPLNSSAVVNCSVHGLPTPALRWTKDSTPLGDGPMLSLSSITFDSNGTYVC 424
Query: 372 SATLEVAGQLIHKNQTRELRVLYGPRLD--ERDCPGNWTWPENSQQTPMCQAWGNPLPEL 429
A+L ++ + Q L V P L E + + +W E + T +C A G+P P+L
Sbjct: 425 EASLPTV-PVLSRTQNFTLLVQGSPELKTAEIEPKADGSWREGDEVTLICSARGHPDPKL 483
Query: 430 KCLKDG---TFPLP-----IGESVT--VTRDLEGTYL-CRARSTQGEVTRKVTVNVLSPR 478
+ G P+P + S+T VT L + C A + G +SP+
Sbjct: 484 SWSQLGGSPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEASNPHGNKRHVFHFGTVSPQ 543
Query: 479 YEIVIITVVAAAVIMGTAGL-STYLYNRQRKIKKYRLQQAQKGTP 522
+ V+A AV +G L Y +RK Q+ +KG P
Sbjct: 544 TSQAGVAVMAVAVSVGLLLLVVAVFYCVRRKGGPCCRQRREKGAP 588
>gi|4507875 vascular cell adhesion molecule 1 isoform a precursor
[Homo sapiens]
Length = 739
Score = 45.8 bits (107), Expect = 1e-04
Identities = 85/403 (21%), Positives = 143/403 (35%), Gaps = 66/403 (16%)
Query: 107 LTVYWTPERVELAPLPSWQ-PVGKNLTLRCQVEGGAPRANLTVVLLRGEKELKREPAVGE 165
L VY +P+ ++ PS + G ++T+ C EG L + K+L
Sbjct: 217 LQVYISPKNTVISVNPSTKLQEGGSVTMTCSSEG------LPAPEIFWSKKLDNGNLQHL 270
Query: 166 PAEVTTTVLVRRDHHGANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVSPR 225
T T++ R + C +G+ L +L P T PR
Sbjct: 271 SGNATLTLIAMRMEDSGIYVC--------EGVNLIGKNRKEVELIVQEKPFTVEISPGPR 322
Query: 226 VL-EVDTQGTVVCSLDGLFPVS---EAQVHLALG----DQRLNPTVTYGNDSFSAKASVS 277
+ ++ + CS+ G S Q+ L + N T+T SF
Sbjct: 323 IAAQIGDSVMLTCSVMGCESPSFSWRTQIDSPLSGKVRSEGTNSTLTLSPVSF------- 375
Query: 278 VTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCE---A 334
E C V G++ E V +YSFP I + G+ VTV C+
Sbjct: 376 -----ENEHSYLCTVTCGHKKLEKGIQVELYSFPRDPEIEMSGGLVNGSSVTVSCKVPSV 430
Query: 335 HPRAKVTLNGVPAQPLGPRAQLL----LKA------------TPEDNGRSFSCSATLEVA 378
+P ++ + + + + + L +K+ T ED G++ C A L +
Sbjct: 431 YPLDRLEIELLKGETILENIEFLEDTDMKSLENKSLEMTFIPTIEDTGKALVCQAKLHID 490
Query: 379 GQLIHKNQTRELRVLY---GPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPEL---KCL 432
Q + + LY PR + E S C + G P P++ + L
Sbjct: 491 DMEFEPKQRQSTQTLYVNVAPRDTTVLVSPSSILEEGSSVNMTCLSQGFPAPKILWSRQL 550
Query: 433 KDGTFPLPIGESVTVT-----RDLEGTYLCRARSTQGEVTRKV 470
+G P+ E+ T+T + G YLC + G ++V
Sbjct: 551 PNGELQ-PLSENATLTLISTKMEDSGVYLCEGINQAGRSRKEV 592
Score = 41.2 bits (95), Expect = 0.002
Identities = 85/392 (21%), Positives = 150/392 (38%), Gaps = 40/392 (10%)
Query: 13 LLVLLGA------LFPGPGNAQTSVSP-SKVILPRGGSVLVTCSTS-CDQPKL---LGIE 61
++V+LGA +F + +P S+ + G SV +TCST+ C+ P I+
Sbjct: 5 MVVILGASNILWIMFAASQAFKIETTPESRYLAQIGDSVSLTCSTTGCESPFFSWRTQID 64
Query: 62 TPLPKKELLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAPL 121
+PL K + + + +C + C + + +Y P+ E+ L
Sbjct: 65 SPLNGKVTNEGTTSTLTMNPVSFGNEHSYLCTATCESRKLEKGIQVEIYSFPKDPEIH-L 123
Query: 122 PSWQPVGKNLTLRCQVEGGAPRANLTVVLLRGEKELK---------REPAVGEPAEVTTT 172
GK +T++C V P L + LL+G+ +K R+ + EVT T
Sbjct: 124 SGPLEAGKPITVKCSVADVYPFDRLEIDLLKGDHLMKSQEFLEDADRKSLETKSLEVTFT 183
Query: 173 VLVRRDHHGANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVSPRV-LEVDT 231
++ + G CR +L + + A +LQ ++ P V+P L+
Sbjct: 184 PVI--EDIGKVLVCRAKLHIDEMD-SVPTVRQAVKELQVYISPKNTVISVNPSTKLQEGG 240
Query: 232 QGTVVCSLDGLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLTCA 291
T+ CS +GL P E L + L GN + + +++ ED G
Sbjct: 241 SVTMTCSSEGL-PAPEIFWSKKLDNGNLQH--LSGNATLTL---IAMRMEDSGIYVCEGV 294
Query: 292 VILGNQSQETLQTV-----TIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTLNGVP 346
++G +E V T+ P P + + T + CE+ + T P
Sbjct: 295 NLIGKNRKEVELIVQEKPFTVEISPGPRIAAQIGDSVMLTCSVMGCESPSFSWRTQIDSP 354
Query: 347 ----AQPLGPRAQLLLKATPEDNGRSFSCSAT 374
+ G + L L +N S+ C+ T
Sbjct: 355 LSGKVRSEGTNSTLTLSPVSFENEHSYLCTVT 386
Score = 36.6 bits (83), Expect = 0.059
Identities = 67/305 (21%), Positives = 120/305 (39%), Gaps = 41/305 (13%)
Query: 210 QTFVLPATPPQLVSPRVLEVDTQGTVVCSLDGL-FPVSEAQVHLALGDQRLNPTVTYGND 268
Q F + TP S + ++ ++ CS G P + + D LN VT N+
Sbjct: 23 QAFKIETTPE---SRYLAQIGDSVSLTCSTTGCESPFFSWRTQI---DSPLNGKVT--NE 74
Query: 269 SFSAKASVSVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPA-PNVILTKPEVSEGTE 327
++ +++ + L A + ++ +Q V IYSFP P + L+ P + G
Sbjct: 75 GTTSTLTMNPVSFGNEHSYLCTATCESRKLEKGIQ-VEIYSFPKDPEIHLSGP-LEAGKP 132
Query: 328 VTVKC---EAHPRAKVTLNGVPAQPLGPRAQLLLKA--------------TP--EDNGRS 368
+TVKC + +P ++ ++ + L + L A TP ED G+
Sbjct: 133 ITVKCSVADVYPFDRLEIDLLKGDHLMKSQEFLEDADRKSLETKSLEVTFTPVIEDIGKV 192
Query: 369 FSCSATL---EVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNP 425
C A L E+ + +EL+V P+ + E T C + G P
Sbjct: 193 LVCRAKLHIDEMDSVPTVRQAVKELQVYISPKNTVISVNPSTKLQEGGSVTMTCSSEGLP 252
Query: 426 LPEL---KCLKDGTFPLPIGES----VTVTRDLEGTYLCRARSTQGEVTRKVTVNVLSPR 478
PE+ K L +G G + + + + G Y+C + G+ ++V + V
Sbjct: 253 APEIFWSKKLDNGNLQHLSGNATLTLIAMRMEDSGIYVCEGVNLIGKNRKEVELIVQEKP 312
Query: 479 YEIVI 483
+ + I
Sbjct: 313 FTVEI 317
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 45.4 bits (106), Expect = 1e-04
Identities = 108/463 (23%), Positives = 173/463 (37%), Gaps = 89/463 (19%)
Query: 63 PLPKKELLLPGNNRKVYELSN--VQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERV---- 116
PL KK L NR V ++ + VQ+ + C + G+ T K + W P +
Sbjct: 2143 PLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK-TEKNYNVNIWVPPNIGGSD 2201
Query: 117 ELAPLPSWQPVGKNLTLRCQVEGGAPRANLTVVLLRGEKELK----REPAVGEPAEVTTT 172
EL L + G ++L C+ G P NL + +G L R + ++ +
Sbjct: 2202 ELTQLTVIE--GNLISLLCE-SSGIPPPNL-IWKKKGSPVLTDSMGRVRILSGGRQLQIS 2257
Query: 173 VLVRRDHHGANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVSPRVLEVDTQ 232
+ + D A +SC + Y LQ ++ P P + V T+
Sbjct: 2258 IAEKSD--AALYSCVAS--------NVAGTAKKEYNLQVYIRPTITNSGSHPTEIIV-TR 2306
Query: 233 GTVV---CSLDGLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEG----- 284
G + C + G+ P PTVT+ D + V DEG
Sbjct: 2307 GKSISLECEVQGIPP----------------PTVTWMKDGHPLIKAKGVEILDEGHILQL 2350
Query: 285 -------TQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPE---VSEGTEVTVKCEA 334
T R C + + +++++ P+ PE V E V++ CEA
Sbjct: 2351 KNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEA 2410
Query: 335 H--PRAKVTL--NGVPAQPL-------GPRAQLLLKATPEDNGRSFSCSATLEVAGQLIH 383
P +T +G P G R L++ T ED G+ ++C AG+
Sbjct: 2411 SGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQ-YTC-VVRNAAGE--- 2465
Query: 384 KNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGE 443
+ + L VL P + + + E T C+ GNP+PE+ KDG PL E
Sbjct: 2466 ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQ-PLQEDE 2524
Query: 444 S---VTVTRDLE---------GTYLCRARSTQGEVTRKVTVNV 474
+ ++ R L+ G Y C A S G +R ++NV
Sbjct: 2525 AHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 44.7 bits (104), Expect = 2e-04
Identities = 96/491 (19%), Positives = 168/491 (34%), Gaps = 77/491 (15%)
Query: 33 PSKVILPRGGSVLVTCSTSCDQPKLLG------IETPLPKKELLLPGNNRKVYELSNVQE 86
P ++ + G V + C P ++ + +P + LP + K+ E + +
Sbjct: 1086 PVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITE-TRTSD 1144
Query: 87 DSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAPLPSWQPVGKNLTLRCQVEGGAPRANL 146
+C + G T L V+ P +++ P VG+ + + C +G P +
Sbjct: 1145 SGMYLCVATNIAGNVTQAVKLNVH-VPPKIQRGPKHLKVQVGQRVDIPCNAQG-TPLPVI 1202
Query: 147 T------VVLLRGEKELKREPAV-----GEPAEVTTTVLVRRDHHGANFSCRTELDLRPQ 195
T +L+ GE + P++ V + G + TE+ L Q
Sbjct: 1203 TWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTD---ETEITLHVQ 1259
Query: 196 GLELFENTSAPYQLQTFVLPATPPQLVSPRVLEVDTQGTVVCSLDGLFPVSEAQVHLALG 255
E+ PY TF ++ P C G + +H
Sbjct: 1260 EPPTVEDLEPPYNT-TFQERVANQRIEFP------------CPAKGTPKPTIKWLHNGRE 1306
Query: 256 DQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNV 315
P ++ D + SVT D G C + + E + ++ P V
Sbjct: 1307 LTGREPGISILEDG-TLLVIASVTPYDNG--EYICVAVNEAGTTERKYNLKVH---VPPV 1360
Query: 316 ILTKPEVS----------------EGTEVTVKCEAHPRAKVTLNGVPAQPLGPRAQLLLK 359
I K +V+ EGT + +VT + + L +
Sbjct: 1361 IKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFR 1420
Query: 360 ATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMC 419
ATPED GR +SC A + +AG + + VL P + + P + N C
Sbjct: 1421 ATPEDAGR-YSCKA-INIAGT---SQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALEC 1475
Query: 420 QAWGNPLPELKCLKDGTFPLPIGES-------------VTVTRDLEGTYLCRARSTQGEV 466
Q G P P++ KDG PL +G+ R+ +G Y C + G+
Sbjct: 1476 QVKGTPFPDIHWFKDGK-PLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQ 1534
Query: 467 TRKVTVNVLSP 477
+ + + + P
Sbjct: 1535 AKDIKLTIYIP 1545
Score = 42.0 bits (97), Expect = 0.001
Identities = 53/245 (21%), Positives = 100/245 (40%), Gaps = 41/245 (16%)
Query: 277 SVTAEDEGTQRLTCAVILGNQSQETLQTV--TIYSFPAPNVILTKPEVSEGTEVTVKCEA 334
+V ED G TC + N + E TV T++ P + +++G ++ + C+A
Sbjct: 4228 NVVLEDSGFY--TC--VANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKA 4283
Query: 335 H----PRAKVTLNG--VPAQ--PLGPRAQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQ 386
P+ T N +PA + ++L+++ +++ ++ C+A V
Sbjct: 4284 TGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGF------- 4336
Query: 387 TRELRVLY--GPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGES 444
+ + +Y P + + D P NW P C+ G+P P ++ + G + I
Sbjct: 4337 VKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGV-DIEISHR 4395
Query: 445 V------------TVTRDLEGTYLCRARSTQGEVTRKVTVNVLSPRYEIVIITVVAAAVI 492
+ TV D G Y C A + G V R +++ + SP IIT+ +
Sbjct: 4396 IRQLGNGSLAIYGTVNED-AGDYTCVATNEAGVVERSMSLTLQSP----PIITLEPVETV 4450
Query: 493 MGTAG 497
+ G
Sbjct: 4451 INAGG 4455
Score = 41.6 bits (96), Expect = 0.002
Identities = 100/459 (21%), Positives = 169/459 (36%), Gaps = 90/459 (19%)
Query: 70 LLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAPLPSWQPV-- 127
+L G + ++ + + C ++ G + + L VY P P+ V
Sbjct: 2247 ILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTR 2306
Query: 128 GKNLTLRCQVEGGAPRANLTVVLLRGEKELKREPAVGEPAEVTTTVLVRRDHHGANFSCR 187
GK+++L C+V+G P TV ++ L + V E +L ++ H ++
Sbjct: 2307 GKSISLECEVQGIPPP---TVTWMKDGHPLIKAKGVEILDE--GHILQLKNIHVSDTGRY 2361
Query: 188 TELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVSPRVLEVDTQGTV--VCSLDGLFPV 245
+ + G+ T Y L P+ SP + V + +V C G+ P+
Sbjct: 2362 VCVAVNVAGM-----TDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGI-PL 2415
Query: 246 SEAQVHLALGDQRLNPTVTYGNDSFSAKASVSV--------------TAEDEGTQRLTCA 291
P++T+ D + S SV T ED G + TC
Sbjct: 2416 ---------------PSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAG--QYTCV 2458
Query: 292 VILGNQSQETLQTVTIYSFPAPNVI----LTKPEVSEGTEVTVKCEA--HPRAKVTLN-- 343
V N + E + + P+++ L +V E VT+ CE +P ++T +
Sbjct: 2459 V--RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKD 2516
Query: 344 GVPAQP-------LGPRAQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGP 396
G P Q G R + GR ++C A+ HK+++ L V P
Sbjct: 2517 GQPLQEDEAHHIISGGRFLQITNVQVPHTGR-YTCLASSPAG----HKSRSFSLNVFVSP 2571
Query: 397 RLDERDCPGNWTWPE------NSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESVTV--- 447
+ GN PE NS + +C+A+ P + KDGT PL ++ +
Sbjct: 2572 TIAGVGSDGN---PEDVTVILNSPTSLVCEAYSYPPATITWFKDGT-PLESNRNIRILPG 2627
Query: 448 ---------TRDLEGTYLCRARSTQGEVTRKVTVNVLSP 477
D G Y C A + GE+ + V V P
Sbjct: 2628 GRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIP 2666
Score = 41.6 bits (96), Expect = 0.002
Identities = 45/168 (26%), Positives = 67/168 (39%), Gaps = 28/168 (16%)
Query: 328 VTVKCEA----------HPRAKVTLNGVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEV 377
+T+ CEA H + + + + L + + P D G ++C A V
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGH-YTCMAA-NV 4153
Query: 378 AGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTF 437
AG + + +L V PR+ R G++T ENSQ C A G P P + KD
Sbjct: 4154 AGS---SSTSTKLTVHVPPRI--RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVL 4208
Query: 438 ---------PLPIGESV--TVTRDLEGTYLCRARSTQGEVTRKVTVNV 474
P GE + V + G Y C A + GE T V++ V
Sbjct: 4209 LANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256
Score = 41.2 bits (95), Expect = 0.002
Identities = 75/310 (24%), Positives = 119/310 (38%), Gaps = 47/310 (15%)
Query: 209 LQTFVLPATPPQLVSPRVLEVDTQGTVVCSLDGLFPVS---EAQVHLALGDQRLNPTVTY 265
LQ V P+ P + V+ V+ Q T+ C G+ S HL DQ N +Y
Sbjct: 3798 LQVHVPPSIAPGPTNMTVI-VNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQN---SY 3853
Query: 266 GNDSFSAKASVSVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPE---V 322
S + +S + +D T T G+ + TV + P I +P V
Sbjct: 3854 RLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQV-----PPSIADEPTDFLV 3908
Query: 323 SEGTEVTVKCEAH----PRAKVTLNGVPAQPLGPRAQLL------LKATPEDNGRSFSCS 372
++ + C A P T NG+ P G ++L + AT ++ ++C
Sbjct: 3909 TKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCV 3968
Query: 373 ATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCL 432
A AG H++ T L V P + + P N+ C+A G P P +
Sbjct: 3969 AR-NAAGSA-HRHVT--LHVHEPPVIQPQ--PSELHVILNNPILLPCEATGTPSPFITWQ 4022
Query: 433 KDGTFPLPIGESVTV-----------TRDLEGTYLCRARSTQGEVTRKVTVN-----VLS 476
K+G G + V R+ GTY+C A++ G K+ +N V+S
Sbjct: 4023 KEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVIS 4082
Query: 477 PRYEIVIITV 486
P + +I V
Sbjct: 4083 PHLKEYVIAV 4092
Score = 40.4 bits (93), Expect = 0.004
Identities = 100/412 (24%), Positives = 152/412 (36%), Gaps = 53/412 (12%)
Query: 99 GQSTAKTFLTVYWTPERVELAPLPSWQPVGKNLTLRCQVEGGAPRANLTVVLLRGEKELK 158
G++T K L V P ++ P +G N+TL C V+G P + + L
Sbjct: 779 GRATGKITLDVGSPPVFIQ-EPADVSMEIGSNVTLPCYVQG-YPEPTIKW------RRLD 830
Query: 159 REPAVGEPAEVTTTVLVRRDHHGANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPA-- 216
P P V++ +R GA F + + EN Q +T V
Sbjct: 831 NMPIFSRPFSVSSISQLRT---GALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGL 887
Query: 217 -TPPQLVSPRVLEV--DTQGTVVCSLDGLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAK 273
P +SP V V Q T+ C+L P+ E + NP +T +D
Sbjct: 888 VAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHI 947
Query: 274 ASVSVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCE 333
V + +D G + + G ++ T +V ++ P EG VT+ C+
Sbjct: 948 ERVQL--QDGGEYTCVASNVAGTNNKTT--SVVVHVLPTIQHGQQILSTIEGIPVTLPCK 1003
Query: 334 AHPRAKVTLNGVPAQPL----------GPRAQLLLKATPEDNGRSFSCSATLEVAGQLIH 383
A K ++ L G L + + + + C+AT AG
Sbjct: 1004 ASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTAT-NTAGYAKR 1062
Query: 384 KNQTRELRVLYGPRL--DER----DCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDG-- 435
K Q L V PR+ D+R D P + + T C+ P P + K+
Sbjct: 1063 KVQ---LTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQL 1119
Query: 436 --------TFPLPIGE-SVTVTRDLE-GTYLCRARSTQGEVTRKVTVNVLSP 477
TF LP G +T TR + G YLC A + G VT+ V +NV P
Sbjct: 1120 ISPFSPRHTF-LPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVP 1170
Score = 39.7 bits (91), Expect = 0.007
Identities = 58/225 (25%), Positives = 89/225 (39%), Gaps = 40/225 (17%)
Query: 282 DEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAH--PRAK 339
D+G + T + G Q+++ T+ I + T V + + ++CE P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPA 1578
Query: 340 VTLNGVPAQPLGPRAQLLLKATPEDNGR---------SFSCSATLEVAGQLIHKNQTREL 390
+T QP+ +Q L D G+ S S + T VA ++ +
Sbjct: 1579 ITWYK-DGQPIMSSSQALYI----DKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHV 1633
Query: 391 RVLYGPRLDERDCPGNWTWPENSQQ------TPMCQAWGNPLPELKCLKDGTFPLPIGES 444
V P ++ GN P N Q T C+A GNP P L LKDG P+ ++
Sbjct: 1634 DVYVPPMIE-----GNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGV-PVKANDN 1687
Query: 445 VTVT---RDLE---------GTYLCRARSTQGEVTRKVTVNVLSP 477
+ + + LE G Y+C A S GE K V+VL P
Sbjct: 1688 IRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVP 1732
Score = 39.3 bits (90), Expect = 0.009
Identities = 101/495 (20%), Positives = 177/495 (35%), Gaps = 78/495 (15%)
Query: 30 SVSPSKVILPRGGSVLVTCSTSCDQPKLLG------IETPLPKKELLLPGNNRKVYELSN 83
S S S V + G SV + C ++ P ++ + T E+L G + + +
Sbjct: 3063 SESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKK-AE 3121
Query: 84 VQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAPLPSWQPVGKNLTLRCQVEGGAPR 143
V + Q +C + G+ L VY P + + +TL C G P
Sbjct: 3122 VSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPP 3181
Query: 144 ANLTVVLLRGEKELKREPAVG-EPAEVTTTVLVRRDHHG--ANFSCRTELDLRPQGLELF 200
T+ L+ K ++ ++ + + + R H N++C +
Sbjct: 3182 ---TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTC------------IA 3226
Query: 201 ENTSAPYQLQTFVLPATPPQLVSPRV-----LEVDTQGTVVCSLDGLFPVSEAQVHLALG 255
N Q F+ PP + + + + +VC+ +G+ P Q L
Sbjct: 3227 SNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGI-PTPLIQW---LK 3282
Query: 256 DQRLNPTVTYGNDSFSAKASVSVT----AEDEGTQRLTCAVILGNQSQETLQTVTIYSFP 311
D + P + + A+ S A T + TC + N + E + + +
Sbjct: 3283 DGK--PIASGETERIRVSANGSTLNIYGALTSDTGKYTC--VATNPAGEEDRIFNLNVYV 3338
Query: 312 APNVILTKPEVSE-----GTEVTVKCEAH----PRAKVTLNGVPAQPLGPRAQLL----- 357
P + K E + T + ++C A P+ NG+P PL +LL
Sbjct: 3339 TPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPL-PLSSHIRLLAAGQV 3397
Query: 358 ---LKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQ 414
++A D ++C A+ H N L+V P +D T + S
Sbjct: 3398 IRIVRAQVSDVA-VYTCVASNRAGVDNKHYN----LQVFAPPNMDNSMGTEEITVLKGSS 3452
Query: 415 QTPMCQAWGNPLPELKCLKDGTFPLPIGESVTVTR------------DLEGTYLCRARST 462
+ C G P P + L+DG PL + +TV+ + G Y C A +
Sbjct: 3453 TSMACITDGTPAPSMAWLRDGQ-PLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNE 3511
Query: 463 QGEVTRKVTVNVLSP 477
GEV++ + VL P
Sbjct: 3512 AGEVSKHFILKVLEP 3526
Score = 39.3 bits (90), Expect = 0.009
Identities = 57/200 (28%), Positives = 85/200 (42%), Gaps = 43/200 (21%)
Query: 310 FPAPNVILTKPEVSEGTE-VTVKCEAHPRAKVTLNGVPA---------QPLGPRAQL--- 356
F PN+ + S GTE +TV + +G PA QPLG A L
Sbjct: 3431 FAPPNM-----DNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVS 3485
Query: 357 -------LLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTW 409
LLKA ED+G+ ++C A+ E AG++ ++ L+VL P ++ + +
Sbjct: 3486 THGMVLQLLKAETEDSGK-YTCIASNE-AGEV---SKHFILKVLEPPHINGSEEHEEISV 3540
Query: 410 PENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESV------------TVTRDLEGTYLC 457
N+ C A G P P++ +KDG PLP + V T + G Y C
Sbjct: 3541 IVNNPLELTCIASGIPAPKMTWMKDGR-PLPQTDQVQTLGGGEVLRISTAQVEDTGRYTC 3599
Query: 458 RARSTQGEVTRKVTVNVLSP 477
A S G+ ++ V V P
Sbjct: 3600 LASSPAGDDDKEYLVRVHVP 3619
Score = 35.4 bits (80), Expect = 0.13
Identities = 60/227 (26%), Positives = 91/227 (40%), Gaps = 40/227 (17%)
Query: 277 SVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEA-- 334
SV D G C V S +T+ P V+ + G+EV++ C A
Sbjct: 580 SVKFNDAGEYH--CMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATG 637
Query: 335 HPRAKV--TLN-----GVPAQPLGPRAQLLLK-ATPEDNGRSFSCSATLEVAGQLIHKNQ 386
+P+ K+ T+N G + L +K A P+D G + C A+ Q
Sbjct: 638 YPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAG-IYGCLASNSAGTD----KQ 692
Query: 387 TRELRVLYGPRL-----DERDCPGNWTWPENSQQTPMCQAWGNPLPELKC------LKDG 435
LR + P+L + G+ T E C+ G P P++K L+
Sbjct: 693 NSTLRYIEAPKLMVVQSELLVALGDITVME-------CKTSGIPPPQVKWFKGDLELRPS 745
Query: 436 TF----PLPIGESVTVTRDLE-GTYLCRARSTQGEVTRKVTVNVLSP 477
TF PL + T+DL+ G Y C A + G T K+T++V SP
Sbjct: 746 TFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSP 792
Score = 32.7 bits (73), Expect = 0.85
Identities = 58/253 (22%), Positives = 92/253 (36%), Gaps = 44/253 (17%)
Query: 261 PTVTYGNDSFSAKASVSVTAEDEG------------TQRLTCAVILGNQSQETLQTVTIY 308
P +T+ D+ S S+T + G C I + E ++ ++
Sbjct: 1950 PVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVH 2009
Query: 309 SFPAPNVILTKPEVSEGTEVTVKCEAH----PRAKVTLNGVPAQPL--------GPRAQL 356
P+ + V V ++CEA P +G P G R
Sbjct: 2010 VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILA 2069
Query: 357 LLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQT 416
L A D GR ++C A + AG+ K + +LRV P + + N + +
Sbjct: 2070 LTSAQISDTGR-YTCVA-VNAAGE---KQRDIDLRVYVPPNIMGEE--QNVSVLISQAVE 2122
Query: 417 PMCQAWGNPLPELKCLKDGTFPL--PIGESVTVTRDL----------EGTYLCRARSTQG 464
+CQ+ P P L LKDG PL G S++ R + G Y C A + G
Sbjct: 2123 LLCQSDAIPPPTLTWLKDG-HPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Query: 465 EVTRKVTVNVLSP 477
+ + VN+ P
Sbjct: 2182 KTEKNYNVNIWVP 2194
Score = 31.6 bits (70), Expect = 1.9
Identities = 53/214 (24%), Positives = 82/214 (38%), Gaps = 30/214 (14%)
Query: 289 TCAVILGNQSQETLQTVTIYSFPAPNVILTKP---EVSEGTEVTVKCEAHPRAKVTL--- 342
TC V + E V +Y P L P +V +T++C+A L
Sbjct: 1617 TCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWL 1676
Query: 343 -NGVPAQP-------LGPRAQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLY 394
+GVP + G + ++ A D G+ + C AT VAG+ K E+ VL
Sbjct: 1677 KDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQ-YICVAT-SVAGE---KEIKYEVDVLV 1731
Query: 395 GPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGT-------FPLPIGESVTV 447
P ++ D + N+ C G+P P + LKDG F + + V
Sbjct: 1732 PPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV 1791
Query: 448 TRDLE----GTYLCRARSTQGEVTRKVTVNVLSP 477
+ G Y C A +T G+ ++ V V P
Sbjct: 1792 IAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVP 1825
Score = 29.3 bits (64), Expect = 9.4
Identities = 38/143 (26%), Positives = 56/143 (39%), Gaps = 24/143 (16%)
Query: 351 GPRAQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLD--ERDCPGNWT 408
G R + +A ED GR ++C A E + ++RVL P + D P T
Sbjct: 2829 GGRVLQIPRAKVEDAGR-YTCVAVNEAGEDSLQY----DVRVLVPPIIKGANSDLPEEVT 2883
Query: 409 WPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGES-----VTVTRDLE---------GT 454
N C + G+P P KDG P+ E ++ R L+ G
Sbjct: 2884 VLVNKSALIECLSSGSPAPRNSWQKDGQ---PLLEDDHHKFLSNGRILQILNTQITDIGR 2940
Query: 455 YLCRARSTQGEVTRKVTVNVLSP 477
Y+C A +T G + +NV P
Sbjct: 2941 YVCVAENTAGSAKKYFNLNVHVP 2963
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 45.4 bits (106), Expect = 1e-04
Identities = 62/225 (27%), Positives = 87/225 (38%), Gaps = 38/225 (16%)
Query: 282 DEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPE---VSEGTEVTVKCEA--HP 336
DEGT +G TV AP + +P V++G VT CE +P
Sbjct: 303 DEGTYMCIAENRVGKMEASATLTVR-----APPQFVVRPRDQIVAQGRTVTFPCETKGNP 357
Query: 337 RAKV----------TLNGVPAQP-----LGPRAQLLLKATPEDNGRSFSCSATLEVAGQL 381
+ V P QP + P L + + + C A L VAG +
Sbjct: 358 QPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQA-LTVAGSI 416
Query: 382 IHKNQTRELRVLYG-PRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDG-TFP- 438
+ K Q VL P P N T + C+A G+PLP + LK+G TFP
Sbjct: 417 LAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPG 476
Query: 439 ----LPIGESVTV-TRDLE----GTYLCRARSTQGEVTRKVTVNV 474
I E T+ ++L GTY C A S+ GE + ++V
Sbjct: 477 RDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 521
Score = 35.0 bits (79), Expect = 0.17
Identities = 32/137 (23%), Positives = 58/137 (42%), Gaps = 14/137 (10%)
Query: 355 QLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQ 414
+L++ T + + ++C T V + + EL V P R P N E
Sbjct: 203 KLMISNTRKSDAGMYTCVGTNMVGER---DSDPAELTVFERPTFLRR--PINQVVLEEEA 257
Query: 415 QTPMCQAWGNPLPELKCLKD------GTFPLPIGESVTVTRDL---EGTYLCRARSTQGE 465
CQ G+P P ++ KD G + + ++ + + + EGTY+C A + G+
Sbjct: 258 VEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGK 317
Query: 466 VTRKVTVNVLSPRYEIV 482
+ T+ V +P +V
Sbjct: 318 MEASATLTVRAPPQFVV 334
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 45.4 bits (106), Expect = 1e-04
Identities = 62/225 (27%), Positives = 87/225 (38%), Gaps = 38/225 (16%)
Query: 282 DEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPE---VSEGTEVTVKCEA--HP 336
DEGT +G TV AP + +P V++G VT CE +P
Sbjct: 287 DEGTYMCIAENRVGKMEASATLTVR-----APPQFVVRPRDQIVAQGRTVTFPCETKGNP 341
Query: 337 RAKV----------TLNGVPAQP-----LGPRAQLLLKATPEDNGRSFSCSATLEVAGQL 381
+ V P QP + P L + + + C A L VAG +
Sbjct: 342 QPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQA-LTVAGSI 400
Query: 382 IHKNQTRELRVLYG-PRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDG-TFP- 438
+ K Q VL P P N T + C+A G+PLP + LK+G TFP
Sbjct: 401 LAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPG 460
Query: 439 ----LPIGESVTV-TRDLE----GTYLCRARSTQGEVTRKVTVNV 474
I E T+ ++L GTY C A S+ GE + ++V
Sbjct: 461 RDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 505
Score = 35.0 bits (79), Expect = 0.17
Identities = 32/137 (23%), Positives = 58/137 (42%), Gaps = 14/137 (10%)
Query: 355 QLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQ 414
+L++ T + + ++C T V + + EL V P R P N E
Sbjct: 187 KLMISNTRKSDAGMYTCVGTNMVGER---DSDPAELTVFERPTFLRR--PINQVVLEEEA 241
Query: 415 QTPMCQAWGNPLPELKCLKD------GTFPLPIGESVTVTRDL---EGTYLCRARSTQGE 465
CQ G+P P ++ KD G + + ++ + + + EGTY+C A + G+
Sbjct: 242 VEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGK 301
Query: 466 VTRKVTVNVLSPRYEIV 482
+ T+ V +P +V
Sbjct: 302 MEASATLTVRAPPQFVV 318
>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
Length = 398
Score = 45.4 bits (106), Expect = 1e-04
Identities = 73/277 (26%), Positives = 113/277 (40%), Gaps = 46/277 (16%)
Query: 253 ALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPA 312
AL D R+ VT S S +V DEG TC++ + VT+ P
Sbjct: 77 ALRDNRIQ-LVTSTPHELSISIS-NVALADEG--EYTCSIFT-MPVRTAKSLVTVLGIPQ 131
Query: 313 PNVILT-KPEVSEGTEVTVKCEAH---PRAKVT-------LNGVPAQ----PLGPR---- 353
+I K + E T+ C++ P A++T L+G P + P G
Sbjct: 132 KPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVS 191
Query: 354 AQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENS 413
+ + + T ED+G S CS E + ++ ++ + VLY P R P + P
Sbjct: 192 SSVTFQVTREDDGASIVCSVNHESL-KGADRSTSQRIEVLYTPTAMIRPDPPH---PREG 247
Query: 414 QQTPM-CQAWGNPLPELKCL-KDGTFPLPIG---ESVTV----TRDLEGTYLCRARSTQG 464
Q+ + C+ GNP+P+ K+G+ P P+ ES + + GTY C A S G
Sbjct: 248 QKLLLHCEGRGNPVPQQYLWEKEGSVP-PLKMTQESALIFPFLNKSDSGTYGCTATSNMG 306
Query: 465 EVTRKVTVNVLSP--------RYEIVIITVVAAAVIM 493
T+NV P Y +I +VA V +
Sbjct: 307 SYKAYYTLNVNDPSPVPSSSSTYHAIIGGIVAFIVFL 343
>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
Length = 432
Score = 45.4 bits (106), Expect = 1e-04
Identities = 73/277 (26%), Positives = 113/277 (40%), Gaps = 46/277 (16%)
Query: 253 ALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPA 312
AL D R+ VT S S +V DEG TC++ + VT+ P
Sbjct: 111 ALRDNRIQ-LVTSTPHELSISIS-NVALADEG--EYTCSIFT-MPVRTAKSLVTVLGIPQ 165
Query: 313 PNVILT-KPEVSEGTEVTVKCEAH---PRAKVT-------LNGVPAQ----PLGPR---- 353
+I K + E T+ C++ P A++T L+G P + P G
Sbjct: 166 KPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVS 225
Query: 354 AQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENS 413
+ + + T ED+G S CS E + ++ ++ + VLY P R P + P
Sbjct: 226 SSVTFQVTREDDGASIVCSVNHESL-KGADRSTSQRIEVLYTPTAMIRPDPPH---PREG 281
Query: 414 QQTPM-CQAWGNPLPELKCL-KDGTFPLPIG---ESVTV----TRDLEGTYLCRARSTQG 464
Q+ + C+ GNP+P+ K+G+ P P+ ES + + GTY C A S G
Sbjct: 282 QKLLLHCEGRGNPVPQQYLWEKEGSVP-PLKMTQESALIFPFLNKSDSGTYGCTATSNMG 340
Query: 465 EVTRKVTVNVLSP--------RYEIVIITVVAAAVIM 493
T+NV P Y +I +VA V +
Sbjct: 341 SYKAYYTLNVNDPSPVPSSSSTYHAIIGGIVAFIVFL 377
>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
Length = 1863
Score = 44.7 bits (104), Expect = 2e-04
Identities = 94/412 (22%), Positives = 146/412 (35%), Gaps = 88/412 (21%)
Query: 122 PSWQPVGKNLTLRCQVEGGAPRA-NLTVVLLRGEKELK-----------REPAVGEPAEV 169
P Q ++TL+ PRA L V+ GE+ + R+P +G V
Sbjct: 336 PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV 395
Query: 170 TTTVLVRRDHHGANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVSPRVLEV 229
+ R G S + + +PQ E+ EN + ++ + +P P V
Sbjct: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIP-------KPEVAWF 448
Query: 230 DTQGTVVCSLDGLFPVSE--AQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQR 287
+GT V +G V E +L L R + TY + +A+ +
Sbjct: 449 -LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG------------Q 495
Query: 288 LTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAH----PRAKVTLN 343
L+C+ L + ++ P+ + +L V EG + ++C PR LN
Sbjct: 496 LSCSWTLQVERLAVMEVA-----PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLN 550
Query: 344 GVPAQ------PLGPRAQLLLKATPEDNGR----------SFSCSATLEVAGQLIHKNQT 387
G P Q G + A PED+G SCSA + V K +
Sbjct: 551 GQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH----EKKSS 606
Query: 388 RELRVLYGPRLDERDCP------GNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPI 441
R+ L + P + + SQ T Q GNP PE+ L +G I
Sbjct: 607 RKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN---EI 663
Query: 442 GESVT----------------VTRDLEGTYLCRARSTQGEVTRKVTVNVLSP 477
ES V + GTY C A ++ GEV + + V P
Sbjct: 664 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 44.7 bits (104), Expect = 2e-04
Identities = 94/412 (22%), Positives = 146/412 (35%), Gaps = 88/412 (21%)
Query: 122 PSWQPVGKNLTLRCQVEGGAPRA-NLTVVLLRGEKELK-----------REPAVGEPAEV 169
P Q ++TL+ PRA L V+ GE+ + R+P +G V
Sbjct: 336 PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV 395
Query: 170 TTTVLVRRDHHGANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVSPRVLEV 229
+ R G S + + +PQ E+ EN + ++ + +P P V
Sbjct: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIP-------KPEVAWF 448
Query: 230 DTQGTVVCSLDGLFPVSE--AQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQR 287
+GT V +G V E +L L R + TY + +A+ +
Sbjct: 449 -LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG------------Q 495
Query: 288 LTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAH----PRAKVTLN 343
L+C+ L + ++ P+ + +L V EG + ++C PR LN
Sbjct: 496 LSCSWTLQVERLAVMEVA-----PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLN 550
Query: 344 GVPAQ------PLGPRAQLLLKATPEDNGR----------SFSCSATLEVAGQLIHKNQT 387
G P Q G + A PED+G SCSA + V K +
Sbjct: 551 GQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH----EKKSS 606
Query: 388 RELRVLYGPRLDERDCP------GNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPI 441
R+ L + P + + SQ T Q GNP PE+ L +G I
Sbjct: 607 RKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN---EI 663
Query: 442 GESVT----------------VTRDLEGTYLCRARSTQGEVTRKVTVNVLSP 477
ES V + GTY C A ++ GEV + + V P
Sbjct: 664 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
>gi|11225258 myelin associated glycoprotein isoform a precursor
[Homo sapiens]
Length = 626
Score = 44.7 bits (104), Expect = 2e-04
Identities = 55/207 (26%), Positives = 82/207 (39%), Gaps = 29/207 (14%)
Query: 294 LGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKC---EAHPRAKVTLNGVPAQPL 350
LG +Q T ++ I+ PEV GTEV V C + P + L+ + + L
Sbjct: 121 LGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGL 180
Query: 351 GPRAQL--------------LLKATP--EDNGRSFSCSATLEVAGQLIHKNQTRELRVLY 394
G A L LL P E NG C A+ + + V Y
Sbjct: 181 GEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASF--PNTTLQFEGYASMDVKY 238
Query: 395 GPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGT-FPLPIGESV-----TVT 448
P + E + + E S + +C A NP P L ++DGT + ES+ VT
Sbjct: 239 PPVIVEMN--SSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVT 296
Query: 449 RDLEGTYLCRARSTQGEVTRKVTVNVL 475
+G Y C A + G+ R V ++V+
Sbjct: 297 PAEDGVYACLAENAYGQDNRTVGLSVM 323
>gi|18104957 myelin associated glycoprotein isoform b precursor
[Homo sapiens]
Length = 582
Score = 44.7 bits (104), Expect = 2e-04
Identities = 55/207 (26%), Positives = 82/207 (39%), Gaps = 29/207 (14%)
Query: 294 LGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKC---EAHPRAKVTLNGVPAQPL 350
LG +Q T ++ I+ PEV GTEV V C + P + L+ + + L
Sbjct: 121 LGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGL 180
Query: 351 GPRAQL--------------LLKATP--EDNGRSFSCSATLEVAGQLIHKNQTRELRVLY 394
G A L LL P E NG C A+ + + V Y
Sbjct: 181 GEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASF--PNTTLQFEGYASMDVKY 238
Query: 395 GPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGT-FPLPIGESV-----TVT 448
P + E + + E S + +C A NP P L ++DGT + ES+ VT
Sbjct: 239 PPVIVEMN--SSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVT 296
Query: 449 RDLEGTYLCRARSTQGEVTRKVTVNVL 475
+G Y C A + G+ R V ++V+
Sbjct: 297 PAEDGVYACLAENAYGQDNRTVGLSVM 323
>gi|4758822 nephrin precursor [Homo sapiens]
Length = 1241
Score = 43.5 bits (101), Expect = 5e-04
Identities = 76/312 (24%), Positives = 114/312 (36%), Gaps = 46/312 (14%)
Query: 54 QPKLLGIETPLPKKELLLPGNNRKVY-------------ELSNVQEDSQPMCYSNCPDGQ 100
+P L+ + E LP +R+V+ EL V S C GQ
Sbjct: 473 EPSLMWYKDSRTVTESRLPQESRRVHLGSVEKSGSTFSRELVLVTGPSDNQAKFTCKAGQ 532
Query: 101 STAKTFLTVYWTPERVELAPLPSWQPVGKNLTLRCQVEGGAPRANLTVVLLRGEK----- 155
+A T L V + P V + S G L L C P NL+ GE+
Sbjct: 533 LSASTQLAVQFPPTNVTILANASALRPGDALNLTCVSVSSNPPVNLSWD-KEGERLEGVA 591
Query: 156 -ELKREPAVGEPAEVTTTVLVRRDHHGANFSCRTELDLRPQGLELFENTSAPYQLQTFVL 214
+R P G A + + V HG +CR EL E S+ Y+L
Sbjct: 592 APPRRAPFKGSAAARSVLLQVSSRDHGQRVTCRA------HSAELRETVSSFYRLNVLY- 644
Query: 215 PATPPQLVSPRVLEVDTQGTVVCSLDGLFPVSEA------QVHLALGDQRLNPTVTYGND 268
P+ + +VL V T V + L PVS + + RL+P +
Sbjct: 645 ---RPEFLGEQVLVV----TAVEQGEALLPVSVSANPAPEAFNWTFRGYRLSPAGGPRHR 697
Query: 269 SFSAKA--SVSVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGT 326
S+ A +VT D+G +L C G + E + ++ P + EV+ G
Sbjct: 698 ILSSGALHLWNVTRADDGLYQLHCQNSEG--TAEARLRLDVHYAPTIRALQDPTEVNVGG 755
Query: 327 EVTVKC--EAHP 336
V + C +A+P
Sbjct: 756 SVDIVCTVDANP 767
>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
Length = 437
Score = 42.7 bits (99), Expect = 8e-04
Identities = 59/242 (24%), Positives = 98/242 (40%), Gaps = 33/242 (13%)
Query: 102 TAKTFLTVYWTPERVELAPLPSWQPVGKNLTLRCQVEGGAPRANLTVVL----LRGEKEL 157
T+K +LTV PE+ +++ S G + L C+ G P A++ ++ K L
Sbjct: 115 TSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYL 174
Query: 158 KREPAVGEPAEVTTTV--LVRRDHHGANFSCRTE---LDLRPQ-GLELFENTSAPYQLQT 211
K E A + V++T+ V R G CR + L+ PQ +++ E Y
Sbjct: 175 KEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLE---IHYTPSV 231
Query: 212 FVLPATP-PQLVSPRVLEVDTQGTVVCSLDGLFPVSEAQVHLALGDQRLNP--TVTYGND 268
++P+TP PQ P +L +++G P+ E + G + +P V G +
Sbjct: 232 KIIPSTPFPQEGQPLILTCESKGK---------PLPEPVLWTKDGGELPDPDRMVVSGRE 282
Query: 269 SFSAKASVSVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEV 328
+ + D GT R +G S E + V PN +L + T
Sbjct: 283 ----LNILFLNKTDNGTYRCEATNTIGQSSAEYVLIV----HDVPNTLLPTTIIPSLTTA 334
Query: 329 TV 330
TV
Sbjct: 335 TV 336
>gi|157168355 CD22 molecule [Homo sapiens]
Length = 847
Score = 42.4 bits (98), Expect = 0.001
Identities = 48/182 (26%), Positives = 73/182 (40%), Gaps = 33/182 (18%)
Query: 311 PAPNVILTKPEVSEGTEVTVKC-----------------EAHP--RAKVTLNGVPAQPLG 351
P P I PE+ E EVT+ C E P +A VT + + +
Sbjct: 140 PFPPHIQLPPEIQESQEVTLTCLLNFSCYGYPIQLQWLLEGVPMRQAAVTSTSLTIKSVF 199
Query: 352 PRAQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPE 411
R++L +G+ +C L+ A N T +L V + P+L+ + P + E
Sbjct: 200 TRSELKFSPQWSHHGKIVTCQ--LQDADGKFLSNDTVQLNVKHTPKLEIKVTPSDAIVRE 257
Query: 412 NSQQTPMCQ-AWGNP-LPELKCLKDG-------TFPLPIGESVTVTRDLEGTYLCRARST 462
T C+ + NP + LKDG TF L + E VT+D G Y C+ +
Sbjct: 258 GDSVTMTCEVSSSNPEYTTVSWLKDGTSLKKQNTFTLNLRE---VTKDQSGKYCCQVSND 314
Query: 463 QG 464
G
Sbjct: 315 VG 316
>gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens]
Length = 1349
Score = 42.4 bits (98), Expect = 0.001
Identities = 29/78 (37%), Positives = 37/78 (47%), Gaps = 9/78 (11%)
Query: 411 ENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGE------SVTVT---RDLEGTYLCRARS 461
E T C A+GNP P + LK+GT G+ S+TVT R+ G Y CRA S
Sbjct: 153 EGGSITMTCTAFGNPKPIVTWLKEGTLLGASGKYQVSDGSLTVTSVSREDRGAYTCRAYS 212
Query: 462 TQGEVTRKVTVNVLSPRY 479
QGE + V P +
Sbjct: 213 IQGEAVHTTHLLVQGPPF 230
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,262,481
Number of Sequences: 37866
Number of extensions: 1210120
Number of successful extensions: 3572
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 98
Number of HSP's that attempted gapping in prelim test: 3198
Number of HSP's gapped (non-prelim): 363
length of query: 532
length of database: 18,247,518
effective HSP length: 107
effective length of query: 425
effective length of database: 14,195,856
effective search space: 6033238800
effective search space used: 6033238800
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.