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Search of human proteins with 167001484
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2
[Homo sapiens]
(906 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2 [H... 1825 0.0
gi|167001419 glutamate receptor, ionotropic, AMPA 1 isoform 1 [H... 1809 0.0
gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1 pre... 1254 0.0
gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2 pr... 1241 0.0
gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1 p... 1235 0.0
gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3 [H... 1226 0.0
gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2 p... 1204 0.0
gi|163659856 glutamate receptor, ionotrophic, AMPA 3 isoform 1 p... 1200 0.0
gi|163659858 glutamate receptor, ionotrophic, AMPA 3 isoform 2 p... 1187 0.0
gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1 ... 623 e-178
gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2 ... 622 e-178
gi|28416444 glutamate receptor, ionotropic, kainate 1 isoform 2 ... 614 e-175
gi|4504117 glutamate receptor, ionotropic, kainate 1 isoform 1 p... 612 e-175
gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor ... 604 e-172
gi|29029597 glutamate receptor KA2 precursor [Homo sapiens] 521 e-147
gi|29029595 glutamate receptor KA1 precursor [Homo sapiens] 520 e-147
gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3 p... 454 e-127
gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3 p... 454 e-127
gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens] 354 2e-97
gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [H... 341 2e-93
gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens] 244 3e-64
gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens] 244 3e-64
gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens] 244 3e-64
gi|55770854 N-methyl-D-aspartate receptor subunit 2C precursor [... 196 8e-50
gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor ... 189 8e-48
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ... 179 1e-44
gi|197313638 N-methyl-D-aspartate receptor subunit 2A isoform 2 ... 177 3e-44
gi|197313636 N-methyl-D-aspartate receptor subunit 2A isoform 1 ... 177 3e-44
gi|4504125 N-methyl-D-aspartate receptor subunit 2A isoform 1 pr... 177 3e-44
gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate... 159 1e-38
>gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2 [Homo
sapiens]
Length = 906
Score = 1825 bits (4726), Expect = 0.0
Identities = 906/906 (100%), Positives = 906/906 (100%)
Query: 1 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQID 60
MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQID
Sbjct: 1 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQID 60
Query: 61 IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ 120
IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ
Sbjct: 61 IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ 120
Query: 121 FVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTT 180
FVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTT
Sbjct: 121 FVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTT 180
Query: 181 TEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDL 240
TEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDL
Sbjct: 181 TEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDL 240
Query: 241 NKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVM 300
NKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVM
Sbjct: 241 NKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVM 300
Query: 301 AEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGR 360
AEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGR
Sbjct: 301 AEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGR 360
Query: 361 RTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYV 420
RTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYV
Sbjct: 361 RTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYV 420
Query: 421 MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE 480
MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE
Sbjct: 421 MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE 480
Query: 481 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW 540
LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW
Sbjct: 481 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW 540
Query: 541 MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ 600
MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ
Sbjct: 541 MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ 600
Query: 601 QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA 660
QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA
Sbjct: 601 QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA 660
Query: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 720
YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES
Sbjct: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 720
Query: 721 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKW 780
TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKW
Sbjct: 721 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKW 780
Query: 781 WYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 840
WYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK
Sbjct: 781 WYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 840
Query: 841 GFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMP 900
GFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMP
Sbjct: 841 GFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMP 900
Query: 901 LGATGL 906
LGATGL
Sbjct: 901 LGATGL 906
>gi|167001419 glutamate receptor, ionotropic, AMPA 1 isoform 1 [Homo
sapiens]
Length = 906
Score = 1809 bits (4686), Expect = 0.0
Identities = 898/906 (99%), Positives = 901/906 (99%)
Query: 1 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQID 60
MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQID
Sbjct: 1 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQID 60
Query: 61 IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ 120
IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ
Sbjct: 61 IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ 120
Query: 121 FVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTT 180
FVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTT
Sbjct: 121 FVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTT 180
Query: 181 TEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDL 240
TEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDL
Sbjct: 181 TEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDL 240
Query: 241 NKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVM 300
NKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVM
Sbjct: 241 NKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVM 300
Query: 301 AEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGR 360
AEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGR
Sbjct: 301 AEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGR 360
Query: 361 RTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYV 420
RTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYV
Sbjct: 361 RTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYV 420
Query: 421 MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE 480
MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE
Sbjct: 421 MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE 480
Query: 481 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW 540
LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW
Sbjct: 481 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW 540
Query: 541 MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ 600
MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ
Sbjct: 541 MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ 600
Query: 601 QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA 660
QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA
Sbjct: 601 QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA 660
Query: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 720
YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES
Sbjct: 661 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 720
Query: 721 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKW 780
TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALR PVNLAVLKL+EQG+LDKLK+KW
Sbjct: 721 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKW 780
Query: 781 WYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 840
WYDKGECGS SKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK
Sbjct: 781 WYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 840
Query: 841 GFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMP 900
GFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMP
Sbjct: 841 GFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMP 900
Query: 901 LGATGL 906
LGATGL
Sbjct: 901 LGATGL 906
>gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1
precursor [Homo sapiens]
Length = 883
Score = 1254 bits (3244), Expect = 0.0
Identities = 607/845 (71%), Positives = 724/845 (85%), Gaps = 6/845 (0%)
Query: 1 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQL-TEPPKLLPQI 59
+ HI G + G + N+IQIGGLFP QE++AFR + Q T +L P I
Sbjct: 4 IMHISVLLSPVLWGLIFGVS-SNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHI 62
Query: 60 DIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSN 119
D + +++SF +T FCSQFS+GVYAIFGFY++++VN +TSFCG LHV FITPSFP D ++
Sbjct: 63 DNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTH 122
Query: 120 QFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILT 179
FV+Q+RP+L+ AL+S+I++Y+W KF Y+YD+DRGLS LQ VLD+AAEK WQVTA+N+
Sbjct: 123 PFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGN 182
Query: 180 TT----EEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGF 235
+E YR LFQDLE KKER V++DCE +++N I+ Q+I + K+ GYHYI+ANLGF
Sbjct: 183 INNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGF 242
Query: 236 MDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYD 295
D DL K + GANV+GFQ+V+Y D++ +K +++W + +++ KYTSALTYD
Sbjct: 243 TDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYD 302
Query: 296 GVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQF 355
V+VM EAF++LR+QRI+ISRRGNAGDCLANPAVPWGQG++I+RAL+QV+ EGL+GN++F
Sbjct: 303 AVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKF 362
Query: 356 NEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL 415
++ G+R NYT++++E+K +G RKIGYW+E DK V T+ +G D S ++N+T +VTTIL
Sbjct: 363 DQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTIL 422
Query: 416 EDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWN 475
E PYVM+KKN EGN+RYEGYCV+LAAEIAKH G+ Y+L IV DGKYGARD DTK WN
Sbjct: 423 ESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWN 482
Query: 476 GMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL 535
GMVGELVYG+AD+A+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL
Sbjct: 483 GMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL 542
Query: 536 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSL 595
AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH+EEFE+GR+ +S+ +NEFGIFNSLWFSL
Sbjct: 543 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSL 602
Query: 596 GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK 655
GAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL+K
Sbjct: 603 GAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSK 662
Query: 656 QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYA 715
QTEIAYGTL++GSTKEFFRRSKIAVF+KMWTYM+SAEPSVFVRTT EG+ RVRKSKGKYA
Sbjct: 663 QTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYA 722
Query: 716 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDK 775
YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGS+LR PVNLAVLKLSEQGVLDK
Sbjct: 723 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDK 782
Query: 776 LKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSE 835
LK+KWWYDKGECG+KDSGSK+KTSALSLSNVAGVFYIL+GGLGLAMLVALIEFCYKSR+E
Sbjct: 783 LKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAE 842
Query: 836 SKRMK 840
+KRMK
Sbjct: 843 AKRMK 847
>gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2
precursor [Homo sapiens]
Length = 883
Score = 1241 bits (3210), Expect = 0.0
Identities = 601/845 (71%), Positives = 719/845 (85%), Gaps = 6/845 (0%)
Query: 1 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQL-TEPPKLLPQI 59
+ HI G + G + N+IQIGGLFP QE++AFR + Q T +L P I
Sbjct: 4 IMHISVLLSPVLWGLIFGVS-SNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHI 62
Query: 60 DIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSN 119
D + +++SF +T FCSQFS+GVYAIFGFY++++VN +TSFCG LHV FITPSFP D ++
Sbjct: 63 DNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTH 122
Query: 120 QFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILT 179
FV+Q+RP+L+ AL+S+I++Y+W KF Y+YD+DRGLS LQ VLD+AAEK WQVTA+N+
Sbjct: 123 PFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGN 182
Query: 180 TT----EEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGF 235
+E YR LFQDLE KKER V++DCE +++N I+ Q+I + K+ GYHYI+ANLGF
Sbjct: 183 INNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGF 242
Query: 236 MDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYD 295
D DL K + GANV+GFQ+V+Y D++ +K +++W + +++ KYTSALTYD
Sbjct: 243 TDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYD 302
Query: 296 GVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQF 355
V+VM EAF++LR+QRI+ISRRGNAGDCLANPAVPWGQG++I+RAL+QV+ EGL+GN++F
Sbjct: 303 AVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKF 362
Query: 356 NEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL 415
++ G+R NYT++++E+K +G RKIGYW+E DK V T+ +G D S ++N+T +VTTIL
Sbjct: 363 DQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTIL 422
Query: 416 EDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWN 475
E PYVM+KKN EGN+RYEGYCV+LAAEIAKH G+ Y+L IV DGKYGARD DTK WN
Sbjct: 423 ESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWN 482
Query: 476 GMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL 535
GMVGELVYG+AD+A+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL
Sbjct: 483 GMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL 542
Query: 536 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSL 595
AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH+EEFE+GR+ +S+ +NEFGIFNSLWFSL
Sbjct: 543 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSL 602
Query: 596 GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK 655
GAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL+K
Sbjct: 603 GAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSK 662
Query: 656 QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYA 715
QTEIAYGTL++GSTKEFFRRSKIAVF+KMWTYM+SAEPSVFVRTT EG+ RVRKSKGKYA
Sbjct: 663 QTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYA 722
Query: 716 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDK 775
YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGS+LR VNLAVLKL+EQG+LDK
Sbjct: 723 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDK 782
Query: 776 LKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSE 835
LK+KWWYDKGECGS SK+KTSALSLSNVAGVFYIL+GGLGLAMLVALIEFCYKSR+E
Sbjct: 783 LKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAE 842
Query: 836 SKRMK 840
+KRMK
Sbjct: 843 AKRMK 847
>gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1
precursor [Homo sapiens]
Length = 902
Score = 1235 bits (3196), Expect = 0.0
Identities = 610/904 (67%), Positives = 729/904 (80%), Gaps = 22/904 (2%)
Query: 10 TGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFAL-------SQLTEPPKLLPQIDIV 62
+GF G +GA FP+++QIGGLF QE+ AFR A+ + P L+P +D +
Sbjct: 13 SGFWGLAMGA-FPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNI 71
Query: 63 NISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFV 122
++SF +T FCSQ+S+GV+AIFG Y++R+V+ LTSFC ALH+ ITPSFP + +QFV
Sbjct: 72 ETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFV 131
Query: 123 LQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTE 182
LQLRP L+ AL+S++DHY+W FV++YD DRG S+LQ +++ A + W V+A+ + +
Sbjct: 132 LQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFND 191
Query: 183 EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNK 242
YR L ++L++++E+ V+DCE ERL IL QI+ + K+ GYHYI+ANLGF DI L +
Sbjct: 192 VSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLER 251
Query: 243 FKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAE 302
F GANVTGFQLV++ + K+M +WK D R++ + PKYTSALTYDGV VMAE
Sbjct: 252 FIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP-PKYTSALTYDGVLVMAE 310
Query: 303 AFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRT 362
F+SLRRQ+IDISRRGNAGDCLANPA PWGQGID++R L+QVR +GLTGNVQF+ GRR
Sbjct: 311 TFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRV 370
Query: 363 NYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVML 422
NYT+ V E+K G RK+GYWN+ DK V G D ++++NRT +VTTI+E PYVM
Sbjct: 371 NYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIMESPYVMY 430
Query: 423 KKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELV 482
KKN FEGND+YEGYCV+LA+EIAKH+G Y++ IV DGKYGARD DTK WNGMVGELV
Sbjct: 431 KKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELV 490
Query: 483 YGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC 542
YG+A++A+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC
Sbjct: 491 YGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC 550
Query: 543 IVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQG 602
IVFAYIGVSVVLFLVSRFSPYEWH+EE E+G++ + NEFGIFNSLWFSLGAFMQQG
Sbjct: 551 IVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQG 610
Query: 603 CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG 662
CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG
Sbjct: 611 CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG 670
Query: 663 TLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTM 722
TL++GSTKEFFRRSKIAV+EKMWTYM+SAEPSVF RTT EG+ RVRKSKGK+A+LLESTM
Sbjct: 671 TLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTM 730
Query: 723 NEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWY 782
NEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+L PVNLAVLKLSE GVLDKLK+KWWY
Sbjct: 731 NEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSEAGVLDKLKNKWWY 790
Query: 783 DKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGF 842
DKGECG KDSGSKDKTSALSLSNVAGVFYIL+GGLGLAMLVALIEFCYKSR+E+KRMK
Sbjct: 791 DKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMK-- 848
Query: 843 CLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMPLG 902
+ +EAI RN + +G GENGRV++ D PK++ + + SSG+ +
Sbjct: 849 -----LTFSEAI------RNKARLSITGSVGENGRVLTPDCPKAVHTGTAIRQSSGLAVI 897
Query: 903 ATGL 906
A+ L
Sbjct: 898 ASDL 901
>gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3 [Homo
sapiens]
Length = 836
Score = 1226 bits (3173), Expect = 0.0
Identities = 587/791 (74%), Positives = 697/791 (88%), Gaps = 4/791 (0%)
Query: 54 KLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSF 113
+L P ID + +++SF +T FCSQFS+GVYAIFGFY++++VN +TSFCG LHV FITPSF
Sbjct: 10 RLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSF 69
Query: 114 PVDTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVT 173
P D ++ FV+Q+RP+L+ AL+S+I++Y+W KF Y+YD+DRGLS LQ VLD+AAEK WQVT
Sbjct: 70 PTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVT 129
Query: 174 AVNILTTT----EEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYI 229
A+N+ +E YR LFQDLE KKER V++DCE +++N I+ Q+I + K+ GYHYI
Sbjct: 130 AINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYI 189
Query: 230 LANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYT 289
+ANLGF D DL K + GANV+GFQ+V+Y D++ +K +++W + +++ KYT
Sbjct: 190 IANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYT 249
Query: 290 SALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGL 349
SALTYD V+VM EAF++LR+QRI+ISRRGNAGDCLANPAVPWGQG++I+RAL+QV+ EGL
Sbjct: 250 SALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGL 309
Query: 350 TGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTY 409
+GN++F++ G+R NYT++++E+K +G RKIGYW+E DK V T+ +G D S ++N+T
Sbjct: 310 SGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTV 369
Query: 410 IVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDP 469
+VTTILE PYVM+KKN EGN+RYEGYCV+LAAEIAKH G+ Y+L IV DGKYGARD
Sbjct: 370 VVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDA 429
Query: 470 DTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF 529
DTK WNGMVGELVYG+AD+A+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF
Sbjct: 430 DTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF 489
Query: 530 SFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFN 589
SFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH+EEFE+GR+ +S+ +NEFGIFN
Sbjct: 490 SFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFN 549
Query: 590 SLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 649
SLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES
Sbjct: 550 SLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 609
Query: 650 AEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRK 709
AEDL+KQTEIAYGTL++GSTKEFFRRSKIAVF+KMWTYM+SAEPSVFVRTT EG+ RVRK
Sbjct: 610 AEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRK 669
Query: 710 SKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSE 769
SKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGS+LR PVNLAVLKLSE
Sbjct: 670 SKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSE 729
Query: 770 QGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFC 829
QGVLDKLK+KWWYDKGECG+KDSGSK+KTSALSLSNVAGVFYIL+GGLGLAMLVALIEFC
Sbjct: 730 QGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFC 789
Query: 830 YKSRSESKRMK 840
YKSR+E+KRMK
Sbjct: 790 YKSRAEAKRMK 800
>gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2
precursor [Homo sapiens]
Length = 884
Score = 1204 bits (3116), Expect = 0.0
Identities = 585/838 (69%), Positives = 693/838 (82%), Gaps = 9/838 (1%)
Query: 10 TGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFAL-------SQLTEPPKLLPQIDIV 62
+GF G +GA FP+++QIGGLF QE+ AFR A+ + P L+P +D +
Sbjct: 13 SGFWGLAMGA-FPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNI 71
Query: 63 NISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFV 122
++SF +T FCSQ+S+GV+AIFG Y++R+V+ LTSFC ALH+ ITPSFP + +QFV
Sbjct: 72 ETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFV 131
Query: 123 LQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTE 182
LQLRP L+ AL+S++DHY+W FV++YD DRG S+LQ +++ A + W V+A+ + +
Sbjct: 132 LQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFND 191
Query: 183 EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNK 242
YR L ++L++++E+ V+DCE ERL IL QI+ + K+ GYHYI+ANLGF DI L +
Sbjct: 192 VSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLER 251
Query: 243 FKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAE 302
F GANVTGFQLV++ + K+M +WK D R++ + PKYTSALTYDGV VMAE
Sbjct: 252 FIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP-PKYTSALTYDGVLVMAE 310
Query: 303 AFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRT 362
F+SLRRQ+IDISRRGNAGDCLANPA PWGQGID++R L+QVR +GLTGNVQF+ GRR
Sbjct: 311 TFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRV 370
Query: 363 NYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVML 422
NYT+ V E+K G RK+GYWN+ DK V G D ++++NRT +VTTI+E PYVM
Sbjct: 371 NYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIMESPYVMY 430
Query: 423 KKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELV 482
KKN FEGND+YEGYCV+LA+EIAKH+G Y++ IV DGKYGARD DTK WNGMVGELV
Sbjct: 431 KKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELV 490
Query: 483 YGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC 542
YG+A++A+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC
Sbjct: 491 YGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC 550
Query: 543 IVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQG 602
IVFAYIGVSVVLFLVSRFSPYEWH+EE E+G++ + NEFGIFNSLWFSLGAFMQQG
Sbjct: 551 IVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQG 610
Query: 603 CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG 662
CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG
Sbjct: 611 CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG 670
Query: 663 TLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTM 722
TL++GSTKEFFRRSKIAV+EKMWTYM+SAEPSVF RTT EG+ RVRKSKGK+A+LLESTM
Sbjct: 671 TLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTM 730
Query: 723 NEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWY 782
NEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+L VNLAVLKL+EQG+LDKLK+KWWY
Sbjct: 731 NEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWY 790
Query: 783 DKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 840
DKGECGS SKDKTSALSLSNVAGVFYIL+GGLGLAMLVALIEFCYKSR+E+KRMK
Sbjct: 791 DKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMK 848
>gi|163659856 glutamate receptor, ionotrophic, AMPA 3 isoform 1
precursor [Homo sapiens]
Length = 894
Score = 1200 bits (3104), Expect = 0.0
Identities = 595/844 (70%), Positives = 698/844 (82%), Gaps = 12/844 (1%)
Query: 7 FFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALS------QLTEPP-KLLPQI 59
F G LG G FPN I IGGLF QEH+AFRFA+ TE P L +
Sbjct: 17 FLVLGLLGHSHGG-FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHV 75
Query: 60 DIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSN 119
D ++ S+SF +T FCSQFS+GVYAIFGFY++ ++N LTSFCGALH F+TPSFP D
Sbjct: 76 DHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADV 135
Query: 120 QFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILT 179
QFV+Q+RP L+ A++S++ HYKW+KFVY+YD +RG S+LQ +++ A + NWQVTA ++
Sbjct: 136 QFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGN 195
Query: 180 TTE-EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDI 238
+ + +R + +++++++E+ ++DCE ER+N IL Q++ L K+ GYHY+LANLGF DI
Sbjct: 196 IKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDI 255
Query: 239 DLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVK 298
L + GAN+TGFQ+VN + + + +Q+W D R+ KYTSALT+D +
Sbjct: 256 LLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAIL 315
Query: 299 VMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEK 358
V+AEAF+ LRRQR+D+SRRG+AGDCLANPAVPW QGIDI+RAL+ V+ +G+TGN+QF+
Sbjct: 316 VIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTY 375
Query: 359 GRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDP 418
GRRTNYT+ V EMK G RK GYWNE ++FVP + D Q D++S +NRT +VTTILE P
Sbjct: 376 GRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFS-DQQISNDSASSENRTIVVTTILESP 434
Query: 419 YVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMV 478
YVM KKN Q EGN+RYEGYCV+LA EIAKHV Y+L IV DGKYGARDP+TK WNGMV
Sbjct: 435 YVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMV 494
Query: 479 GELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYE 538
GELVYGRAD+AVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYE
Sbjct: 495 GELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYE 554
Query: 539 IWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEF-EEGRD-QTTSDQSNEFGIFNSLWFSLG 596
IWMCIVFAYIGVSVVLFLVSRFSPYEWH E+ EE RD Q+ D NEFGIFNSLWFSLG
Sbjct: 555 IWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLG 614
Query: 597 AFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ 656
AFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ
Sbjct: 615 AFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ 674
Query: 657 TEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAY 716
TEIAYGTL++GSTKEFFRRSKIAV+EKMW+YMKSAEPSVF +TT +G+ RVRKSKGK+A+
Sbjct: 675 TEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAF 734
Query: 717 LLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKL 776
LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSAL PVNLAVLKLSEQG+LDKL
Sbjct: 735 LLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSEQGILDKL 794
Query: 777 KSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSES 836
K+KWWYDKGECG+KDSGSKDKTSALSLSNVAGVFYIL+GGLGLAM+VALIEFCYKSR+ES
Sbjct: 795 KNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAES 854
Query: 837 KRMK 840
KRMK
Sbjct: 855 KRMK 858
>gi|163659858 glutamate receptor, ionotrophic, AMPA 3 isoform 2
precursor [Homo sapiens]
Length = 894
Score = 1187 bits (3071), Expect = 0.0
Identities = 590/844 (69%), Positives = 693/844 (82%), Gaps = 12/844 (1%)
Query: 7 FFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALS------QLTEPP-KLLPQI 59
F G LG G FPN I IGGLF QEH+AFRFA+ TE P L +
Sbjct: 17 FLVLGLLGHSHGG-FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHV 75
Query: 60 DIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSN 119
D ++ S+SF +T FCSQFS+GVYAIFGFY++ ++N LTSFCGALH F+TPSFP D
Sbjct: 76 DHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADV 135
Query: 120 QFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILT 179
QFV+Q+RP L+ A++S++ HYKW+KFVY+YD +RG S+LQ +++ A + NWQVTA ++
Sbjct: 136 QFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGN 195
Query: 180 TTE-EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDI 238
+ + +R + +++++++E+ ++DCE ER+N IL Q++ L K+ GYHY+LANLGF DI
Sbjct: 196 IKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDI 255
Query: 239 DLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVK 298
L + GAN+TGFQ+VN + + + +Q+W D R+ KYTSALT+D +
Sbjct: 256 LLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAIL 315
Query: 299 VMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEK 358
V+AEAF+ LRRQR+D+SRRG+AGDCLANPAVPW QGIDI+RAL+ V+ +G+TGN+QF+
Sbjct: 316 VIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTY 375
Query: 359 GRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDP 418
GRRTNYT+ V EMK G RK GYWNE ++FVP + D Q D++S +NRT +VTTILE P
Sbjct: 376 GRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFS-DQQISNDSASSENRTIVVTTILESP 434
Query: 419 YVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMV 478
YVM KKN Q EGN+RYEGYCV+LA EIAKHV Y+L IV DGKYGARDP+TK WNGMV
Sbjct: 435 YVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMV 494
Query: 479 GELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYE 538
GELVYGRAD+AVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYE
Sbjct: 495 GELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYE 554
Query: 539 IWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEF-EEGRD-QTTSDQSNEFGIFNSLWFSLG 596
IWMCIVFAYIGVSVVLFLVSRFSPYEWH E+ EE RD Q+ D NEFGIFNSLWFSLG
Sbjct: 555 IWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLG 614
Query: 597 AFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ 656
AFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ
Sbjct: 615 AFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ 674
Query: 657 TEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAY 716
TEIAYGTL++GSTKEFFRRSKIAV+EKMW+YMKSAEPSVF +TT +G+ RVRKSKGK+A+
Sbjct: 675 TEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAF 734
Query: 717 LLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKL 776
LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSAL VNLAVLKL+EQG+LDKL
Sbjct: 735 LLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGNAVNLAVLKLNEQGLLDKL 794
Query: 777 KSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSES 836
K+KWWYDKGECGS SKDKTSALSLSNVAGVFYIL+GGLGLAM+VALIEFCYKSR+ES
Sbjct: 795 KNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAES 854
Query: 837 KRMK 840
KRMK
Sbjct: 855 KRMK 858
>gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1
precursor [Homo sapiens]
Length = 908
Score = 623 bits (1607), Expect = e-178
Identities = 347/848 (40%), Positives = 512/848 (60%), Gaps = 54/848 (6%)
Query: 25 IQIGGLFPNQQS----QEHAAFRFALSQLTEPPKLLPQIDI------VNISDSFEMTYRF 74
++ GG+F +S E AFRFA++ + LLP + +N+ DSFE + +
Sbjct: 36 LRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKA 95
Query: 75 CSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFP---VDTSNQFVLQLRPE--- 128
C Q S GV AIFG + N + S C AL V I + D + F + L P+
Sbjct: 96 CDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSS 155
Query: 129 LQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTEEGYRML 188
L A++ ++ +KW+ +YD GL LQ+++ + N ++ + T++ + L
Sbjct: 156 LSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKDA-KPL 214
Query: 189 FQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNKFKESGA 248
+++++ KE V+ DC E IL Q + + YHYI L +D+ ++ SG
Sbjct: 215 LKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGV 274
Query: 249 NVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKR----PKYTSALTYDGVKVMAEAF 304
N+TGF+++N +T + I+++W + + D +AL YD V V++ A
Sbjct: 275 NMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAV 334
Query: 305 QSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNE-KGRRTN 363
Q + + + N PW G +++ +EGLTG + FN+ G RT+
Sbjct: 335 QQFPQMTVSSLQ--------CNRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTD 386
Query: 364 YTLHVIEMKHDGIRKIGYWNEDDKFVPAA----TDAQAGGD---NSSVQNRTYIVTTILE 416
+ L VI +K +G+ KIG W+ PA+ T++Q G S+ NR+ IVTTILE
Sbjct: 387 FDLDVISLKEEGLEKIGTWD------PASGLNMTESQKGKPANITDSLSNRSLIVTTILE 440
Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476
+PYV+ KK+ GNDR+EGYC++L E++ +G++Y + +V DGKYGA+D WNG
Sbjct: 441 EPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDANGQWNG 500
Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLA 536
MV EL+ +AD+AVAPL IT VRE+VIDFSKPFM+LGISI+ +KP + PGVFSFL+PL+
Sbjct: 501 MVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLS 560
Query: 537 YEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLG 596
+IWM I+ AY+GVS VLF+++RFSPYEW++ + + N F + NS WF +G
Sbjct: 561 PDIWMYILLAYLGVSCVLFVIARFSPYEWYN---PHPCNPDSDVVENNFTLLNSFWFGVG 617
Query: 597 AFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ 656
A MQQG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFLTVERM SPI+SA+DLAKQ
Sbjct: 618 ALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQ 677
Query: 657 TEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAY 716
T+I YG +E G+T FF++SKI+ ++KMW +M S SV V++ EEG+ RV S YA+
Sbjct: 678 TKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTS--DYAF 735
Query: 717 LLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKL 776
L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R + +A+L+L E+G L +
Sbjct: 736 LMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMM 794
Query: 777 KSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSES 836
K KWW G C ++S + SAL + N+ G+F +L GL L++ VA+ EF YKS+ +
Sbjct: 795 KEKWWRGNG-CPEEES---KEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNA 850
Query: 837 K-RMKGFC 843
+ + FC
Sbjct: 851 QLEKRSFC 858
>gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2
precursor [Homo sapiens]
Length = 869
Score = 622 bits (1604), Expect = e-178
Identities = 346/844 (40%), Positives = 510/844 (60%), Gaps = 53/844 (6%)
Query: 25 IQIGGLFPNQQS----QEHAAFRFALSQLTEPPKLLPQIDI------VNISDSFEMTYRF 74
++ GG+F +S E AFRFA++ + LLP + +N+ DSFE + +
Sbjct: 36 LRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKA 95
Query: 75 CSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFP---VDTSNQFVLQLRPE--- 128
C Q S GV AIFG + N + S C AL V I + D + F + L P+
Sbjct: 96 CDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSS 155
Query: 129 LQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTEEGYRML 188
L A++ ++ +KW+ +YD GL LQ+++ + N ++ + T++ + L
Sbjct: 156 LSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKDA-KPL 214
Query: 189 FQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNKFKESGA 248
+++++ KE V+ DC E IL Q + + YHYI L +D+ ++ SG
Sbjct: 215 LKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGV 274
Query: 249 NVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKR----PKYTSALTYDGVKVMAEAF 304
N+TGF+++N +T + I+++W + + D +AL YD V V++ A
Sbjct: 275 NMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAV 334
Query: 305 QSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNE-KGRRTN 363
Q + + + N PW G +++ +EGLTG + FN+ G RT+
Sbjct: 335 QQFPQMTVSSLQ--------CNRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTD 386
Query: 364 YTLHVIEMKHDGIRKIGYWNEDDKFVPAA----TDAQAGGD---NSSVQNRTYIVTTILE 416
+ L VI +K +G+ KIG W+ PA+ T++Q G S+ NR+ IVTTILE
Sbjct: 387 FDLDVISLKEEGLEKIGTWD------PASGLNMTESQKGKPANITDSLSNRSLIVTTILE 440
Query: 417 DPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNG 476
+PYV+ KK+ GNDR+EGYC++L E++ +G++Y + +V DGKYGA+D WNG
Sbjct: 441 EPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDANGQWNG 500
Query: 477 MVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLA 536
MV EL+ +AD+AVAPL IT VRE+VIDFSKPFM+LGISI+ +KP + PGVFSFL+PL+
Sbjct: 501 MVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLS 560
Query: 537 YEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLG 596
+IWM I+ AY+GVS VLF+++RFSPYEW++ + + N F + NS WF +G
Sbjct: 561 PDIWMYILLAYLGVSCVLFVIARFSPYEWYN---PHPCNPDSDVVENNFTLLNSFWFGVG 617
Query: 597 AFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ 656
A MQQG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFLTVERM SPI+SA+DLAKQ
Sbjct: 618 ALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQ 677
Query: 657 TEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAY 716
T+I YG +E G+T FF++SKI+ ++KMW +M S SV V++ EEG+ RV S YA+
Sbjct: 678 TKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTS--DYAF 735
Query: 717 LLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKL 776
L+EST E++ QR C+ ++GG +DSKGYG+ TP GS R + +A+L+L E+G L +
Sbjct: 736 LMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMM 794
Query: 777 KSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSES 836
K KWW G C ++S + SAL + N+ G+F +L GL L++ VA+ EF YKS+ +
Sbjct: 795 KEKWWRGNG-CPEEES---KEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNA 850
Query: 837 KRMK 840
+ K
Sbjct: 851 QLEK 854
>gi|28416444 glutamate receptor, ionotropic, kainate 1 isoform 2
precursor [Homo sapiens]
Length = 905
Score = 614 bits (1584), Expect = e-175
Identities = 343/847 (40%), Positives = 515/847 (60%), Gaps = 42/847 (4%)
Query: 12 FLGAVVGANFPNNIQIGGLFPNQQSQ----EHAAFRFALSQLTEPPKLLPQ------IDI 61
FL ++ P ++IGG+F +++ E AF+FA++ + L+P I
Sbjct: 24 FLCYILPQTAPQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQR 83
Query: 62 VNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFP---VDTS 118
+N+ DSFE + R C Q + GV A+FG +V+ + S C AL V I + VD
Sbjct: 84 INLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNK 143
Query: 119 NQFVLQLRPE---LQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAV 175
+ F + L P+ + A++ ++ +Y W+ +Y+ GL LQ+++ + N ++ +
Sbjct: 144 DLFYINLYPDYAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIK-I 202
Query: 176 NILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGF 235
L + + + L ++++K KE V+ DC E IL QI+ + YHY L
Sbjct: 203 RQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDL 262
Query: 236 MDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWK----NSDARDHTRVDWKRPKYTSA 291
+DL ++ SG N+TGF+L+N + + I+++W + R T + +A
Sbjct: 263 FALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAA 322
Query: 292 LTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTG 351
L YD V ++A A S R ++ +S + PW G +++ R++GLTG
Sbjct: 323 LMYDAVYMVAIA--SHRASQLTVS------SLQCHRHKPWRLGPRFMNLIKEARWDGLTG 374
Query: 352 NVQFNE-KGRRTNYTLHVIEMKHDGIRKIGYWNEDDKF-VPAATDAQAGGDNSSVQNRTY 409
++ FN+ G R ++ L +I +K +G KIG WN + + + ++ S+ NRT
Sbjct: 375 HITFNKTNGLRKDFDLDIISLKEEGTEKIGIWNSNSGLNMTDSNKDKSSNITDSLANRTL 434
Query: 410 IVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDP 469
IVTTILE+PYVM +K+ GNDR+EGYC++L E++ +G+ Y +++V DGKYGA++
Sbjct: 435 IVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQN- 493
Query: 470 DTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF 529
D WNGMV EL+ RAD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +KP + PGVF
Sbjct: 494 DKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVF 553
Query: 530 SFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFN 589
SFL+PL+ +IWM ++ A +GVS VLF+++RF+PYEW++ + + N F + N
Sbjct: 554 SFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPH---PCNPDSDVVENNFTLLN 610
Query: 590 SLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 649
S WF +GA MQQG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFLTVERM SPI+S
Sbjct: 611 SFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDS 670
Query: 650 AEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRK 709
A+DLAKQT+I YG + GST FF++SKI+ +EKMW +M S + + VR ++EG+ RV
Sbjct: 671 ADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLT 730
Query: 710 SKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSE 769
+ YA L+EST EY+ QR C+ ++GG +DSKGYG+ TP GS R + +A+L+L E
Sbjct: 731 T--DYALLMESTSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQE 787
Query: 770 QGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFC 829
+G L +K KWW G C +D+ + SAL + N+ G+F +L GL L++ VA+ EF
Sbjct: 788 EGKLHMMKEKWWRGNG-CPEEDN---KEASALGVENIGGIFIVLAAGLVLSVFVAIGEFI 843
Query: 830 YKSRSES 836
YKSR +
Sbjct: 844 YKSRKNN 850
>gi|4504117 glutamate receptor, ionotropic, kainate 1 isoform 1
precursor [Homo sapiens]
Length = 918
Score = 612 bits (1579), Expect = e-175
Identities = 352/908 (38%), Positives = 533/908 (58%), Gaps = 62/908 (6%)
Query: 12 FLGAVVGANFPNNIQIGGLFPNQQSQ----EHAAFRFALSQLTEPPKLLPQ------IDI 61
FL ++ P ++IGG+F +++ E AF+FA++ + L+P I
Sbjct: 24 FLCYILPQTAPQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQR 83
Query: 62 VNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFP---VDTS 118
+N+ DSFE + R C Q + GV A+FG +V+ + S C AL V I + VD
Sbjct: 84 INLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNK 143
Query: 119 NQFVLQLRPE---LQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAV 175
+ F + L P+ + A++ ++ +Y W+ +Y+ GL LQ+++ + N ++ +
Sbjct: 144 DLFYINLYPDYAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIK-I 202
Query: 176 NILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGF 235
L + + + L ++++K KE V+ DC E IL QI+ + YHY L
Sbjct: 203 RQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDL 262
Query: 236 MDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWK----NSDARDHTRVDWKRPKYTSA 291
+DL ++ SG N+TGF+L+N + + I+++W + R T + +A
Sbjct: 263 FALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAA 322
Query: 292 LTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTG 351
L YD V ++A A S R ++ +S + PW G +++ R++GLTG
Sbjct: 323 LMYDAVYMVAIA--SHRASQLTVS------SLQCHRHKPWRLGPRFMNLIKEARWDGLTG 374
Query: 352 NVQFNE-KGRRTNYTLHVIEMKHDGI---------------RKIGYWNEDDKF-VPAATD 394
++ FN+ G R ++ L +I +K +G +KIG WN + + +
Sbjct: 375 HITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTDSNK 434
Query: 395 AQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSY 454
++ S+ NRT IVTTILE+PYVM +K+ GNDR+EGYC++L E++ +G+ Y
Sbjct: 435 DKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIY 494
Query: 455 RLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGI 514
+++V DGKYGA++ D WNGMV EL+ RAD+AVAPLTIT VRE+VIDFSKPFM+LGI
Sbjct: 495 DVKLVPDGKYGAQN-DKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGI 553
Query: 515 SIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGR 574
SI+ +KP + PGVFSFL+PL+ +IWM ++ A +GVS VLF+++RF+PYEW++
Sbjct: 554 SILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPH---PC 610
Query: 575 DQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANL 634
+ + N F + NS WF +GA MQQG ++ P++LS RIVGG+WWFFTLIIISSYTANL
Sbjct: 611 NPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANL 670
Query: 635 AAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPS 694
AAFLTVERM SPI+SA+DLAKQT+I YG + GST FF++SKI+ +EKMW +M S + +
Sbjct: 671 AAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQT 730
Query: 695 VFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGS 754
VR ++EG+ RV + YA L+EST EY+ QR C+ ++GG +DSKGYG+ TP GS
Sbjct: 731 ALVRNSDEGIQRVLTT--DYALLMESTSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGS 787
Query: 755 ALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILI 814
R + +A+L+L E+G L +K KWW G C +D+ + SAL + N+ G+F +L
Sbjct: 788 PYRDKITIAILQLQEEGKLHMMKEKWWRGNG-CPEEDN---KEASALGVENIGGIFIVLA 843
Query: 815 GGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGE 874
GL L++ VA+ EF YKSR + + FC + T P NS +G + E
Sbjct: 844 AGLVLSVFVAIGEFIYKSRKNNDIEQAFCFFYGLQCKQ-----THPTNSTSGTTLSTDLE 898
Query: 875 NGRVVSHD 882
G+++ +
Sbjct: 899 CGKLIREE 906
>gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor
[Homo sapiens]
Length = 919
Score = 604 bits (1558), Expect = e-172
Identities = 340/849 (40%), Positives = 511/849 (60%), Gaps = 49/849 (5%)
Query: 22 PNNIQIGGLF-----PNQQ---SQEHAAFRFALSQLTEPPKLLPQ------IDIVNISDS 67
P+ I+IGG+F PN Q ++EHA FRF+ + + LLP I ++ DS
Sbjct: 33 PHVIRIGGIFEYADGPNAQVMNAEEHA-FRFSANIINRNRTLLPNTTLTYDIQRIHFHDS 91
Query: 68 FEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSF---PVDTSNQFVLQ 124
FE T + C Q + GV AIFG + N + S C AL V I + P+D + F +
Sbjct: 92 FEATKKACDQLALGVVAIFGPSQGSCTNAVQSICNALEVPHIQLRWKHHPLDNKDTFYVN 151
Query: 125 LRPE---LQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTT 181
L P+ L A++ ++ + KW+ +YD GL LQ+++ + N ++ + L
Sbjct: 152 LYPDYASLSHAILDLVQYLKWRSATVVYDDSTGLIRLQELIMAPSRYNIRLK-IRQLPID 210
Query: 182 EEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLN 241
+ R L +++++ +E ++ DC IL Q + + YH+I L +DL
Sbjct: 211 SDDSRPLLKEMKRGREFRIIFDCSHTMAAQILKQAMAMGMMTEYYHFIFTTLDLYALDLE 270
Query: 242 KFKESGANVTGFQLVNYTDTIPAKIMQQWK----NSDARDHTRVDWKRPKYTSALTYDGV 297
++ SG N+TGF+++N + + I+++W + R + + +AL YD V
Sbjct: 271 PYRYSGVNLTGFRILNVDNPHVSAIVEKWSMERLQAAPRSESGLLDGVMMTDAALLYDAV 330
Query: 298 KVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNE 357
+++ +Q + + N+ C + A W G +++ ++EGLTG + FN+
Sbjct: 331 HIVSVCYQRAPQMTV------NSLQCHRHKA--WRFGGRFMNFIKEAQWEGLTGRIVFNK 382
Query: 358 -KGRRTNYTLHVIEMKHDGIRKIGYWNEDDKF-VPAATDAQAGGDNSSVQNRTYIVTTIL 415
G RT++ L +I +K DG+ K+G W+ D + + S+ NR+ IVTT+L
Sbjct: 383 TSGLRTDFDLDIISLKEDGLEKVGVWSPADGLNITEVAKGRGPNVTDSLTNRSLIVTTVL 442
Query: 416 EDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWN 475
E+P+VM +K+ GNDR+EGYC++L E+A +G+SY + +V DGKYGA+D D WN
Sbjct: 443 EEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQD-DKGQWN 501
Query: 476 GMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL 535
GMV EL+ +AD+AVAPLTIT VRE+ IDFSKPFM+LG+SI+ +KP + P VFSFL+PL
Sbjct: 502 GMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKPNGTNPSVFSFLNPL 561
Query: 536 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSL 595
+ +IWM ++ AY+GVS VLF+++RFSPYEW+ + N F + NS WF +
Sbjct: 562 SPDIWMYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPGSEVVE---NNFTLLNSFWFGM 618
Query: 596 GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK 655
G+ MQQG ++ P++LS RI+GG+WWFFTLIIISSYTANLAAFLTVERM SPI+SA+DLAK
Sbjct: 619 GSLMQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAK 678
Query: 656 QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYA 715
QT+I YG ++ G+T FF++SKI+ FEKMW +M S++PS V+ EEG+ R + YA
Sbjct: 679 QTKIEYGAVKDGATMTFFKKSKISTFEKMWAFM-SSKPSALVKNNEEGIQRALTA--DYA 735
Query: 716 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDK 775
L+EST EY+ QR C+ ++GG +DSKGYGI TP GS R + +A+L+L E+ L
Sbjct: 736 LLMESTTIEYVTQRN-CNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHI 794
Query: 776 LKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSE 835
+K KWW G C +++ + SAL + + G+F +L GL L++LVA+ EF YK R
Sbjct: 795 MKEKWWRGSG-CPEEEN---KEASALGIQKIGGIFIVLAAGLVLSVLVAVGEFVYKLRKT 850
Query: 836 SKR-MKGFC 843
++R + FC
Sbjct: 851 AEREQRSFC 859
>gi|29029597 glutamate receptor KA2 precursor [Homo sapiens]
Length = 980
Score = 521 bits (1341), Expect = e-147
Identities = 312/833 (37%), Positives = 463/833 (55%), Gaps = 34/833 (4%)
Query: 52 PPKLLPQIDIVNIS--DSFEMTYRFCSQFSKGVYAIFG-FYERRTVNMLTSFCGALHVCF 108
P K ++DI + +E T C KGV ++ G + + ++ CG +
Sbjct: 58 PAKARVEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSPASASTVSHICGEKEIPH 117
Query: 109 ITPSFPVDTSNQFV----LQLRPELQD---ALISIIDHYKWQKFVYIYDADRGLSVLQKV 161
I Q++ + L P +D A+ I+ + + I L L+++
Sbjct: 118 IKVGPEETPRLQYLRFASVSLYPSNEDVSLAVSRILKSFNYPSASLICAKAECLLRLEEL 177
Query: 162 LDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEK 221
+ + +V +L + + +L +++ K +++D + + IL + +L
Sbjct: 178 VRGFLISK-ETLSVRMLDDSRDPTPLL-KEIRDDKVSTIIIDANASISHLILRKASELGM 235
Query: 222 NGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRV 281
Y YIL + F + L+ E +N+ GF + N + + ++ S +
Sbjct: 236 TSAFYKYILTTMDFPILHLDGIVEDSSNILGFSMFNTSHPFYPEFVRSLNMSWRENCEAS 295
Query: 282 DWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRAL 341
+ P ++AL +D V V+ A + L R S+ A W G + L
Sbjct: 296 TYLGPALSAALMFDAVHVVVSAVRELNR-----SQEIGVKPLACTSANIWPHGTSLMNYL 350
Query: 342 QQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDN 401
+ V ++GLTG V+FN KG+RTNYTL ++E G R+IG W + AT +
Sbjct: 351 RMVEYDGLTGRVEFNSKGQRTNYTLRILEKSRQGHREIGVWYSNRTLAMNATTLDINL-S 409
Query: 402 SSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSD 461
++ N+T +VTTILE+PYVM + N GN+R+EG+CV++ E+A+ + + YRL +V D
Sbjct: 410 QTLANKTLVVTTILENPYVMRRPNFQALSGNERFEGFCVDMLRELAELLRFRYRLRLVED 469
Query: 462 GKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKP 521
G YGA +P+ +W GMVGEL+ +AD+AVA TIT RE+VIDFSKPFM+LGISI+ +
Sbjct: 470 GLYGAPEPNG-SWTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVH 528
Query: 522 QKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEE-FEEGRDQTTSD 580
KPG FSFLDP + +W+ ++ AY+ VS VLFL +R SPYEW++ R
Sbjct: 529 MGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILE- 587
Query: 581 QSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 640
N++ + NSLWF +G FMQQG +I PR+LS R V GVWW FTLIIISSYTANLAAFLTV
Sbjct: 588 --NQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTV 645
Query: 641 ERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTT 700
+RM P+ESA+DLA QT I YGT+ AGST FF+ S+ +++MW YM+S +PSVFV++T
Sbjct: 646 QRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVFVKST 705
Query: 701 EEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPV 760
EEG+ RV S +YA+LLESTMNEY +R C+ ++GG LD+KGYGI P GS R +
Sbjct: 706 EEGIARVLNS--RYAFLLESTMNEY-HRRLNCNLTQIGGLLDTKGYGIGMPLGSPFRDEI 762
Query: 761 NLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLA 820
LA+L+L E L+ LK KWW + G C ++ + L + N+ G+F +LI GL +A
Sbjct: 763 TLAILQLQENNRLEILKRKWW-EGGRCPKEED---HRAKGLGMENIGGIFIVLICGLIIA 818
Query: 821 MLVALIEFCYKS-RSESKRMKGFCLIPQQSINEAI---RTSTLPRNSGAGASS 869
+ VA++EF + + RS C Q + A+ +TS R G S
Sbjct: 819 VFVAVMEFIWSTRRSAESEEVSVCQEMLQELRHAVSCRKTSRSRRRRRPGGPS 871
>gi|29029595 glutamate receptor KA1 precursor [Homo sapiens]
Length = 956
Score = 520 bits (1338), Expect = e-147
Identities = 323/878 (36%), Positives = 482/878 (54%), Gaps = 57/878 (6%)
Query: 16 VVGANFPNNIQIGGLF--PNQQSQ-EHAAFRFALSQLTEPPKLLP----QIDIVNI--SD 66
V+ A P++++I + P + S+ E + A +++ P+ L ++DI +
Sbjct: 16 VMVACSPHSLRIAAILDDPMECSRGERLSITLAKNRINRAPERLGKAKVEVDIFELLRDS 75
Query: 67 SFEMTYRFCSQFSKGVYAIFG-FYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFV--- 122
+E C KGV A+ G + +++++ CG V P F V +FV
Sbjct: 76 EYETAETMCQILPKGVVAVLGPSSSPASSSIISNICGEKEV----PHFKV-APEEFVKFQ 130
Query: 123 ------LQLRPELQD---ALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVT 173
L L P D A+ I++ + I L L+K+L
Sbjct: 131 FQRFTTLNLHPSNTDISVAVAGILNFFNCTTACLICAKAECLLNLEKLLRQFLISK-DTL 189
Query: 174 AVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANL 233
+V +L T + +L +++ K +++ + + IL + +L Y YI NL
Sbjct: 190 SVRMLDDTRDPTPLL-KEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNL 248
Query: 234 GFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALT 293
F ++ + N+ GF + N + + Q S + V + P +SAL
Sbjct: 249 EFSLQRMDSLVDDRVNILGFSIFNQSHAFFQEFAQSLNQSWQENCDHVPFTGPALSSALL 308
Query: 294 YDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNV 353
+D V + A Q L R S+ A W G + L+ V EGLTG++
Sbjct: 309 FDAVYAVVTAVQELNR-----SQEIGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLTGHI 363
Query: 354 QFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTT 413
+FN KG+R+NY L +++ +G R+IG W+ + + + A + ++ N T +VTT
Sbjct: 364 EFNSKGQRSNYALKILQFTRNGFRQIGQWHVAEG-LSMDSHLYASNISDTLFNTTLVVTT 422
Query: 414 ILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKA 473
ILE+PY+MLK N + EGNDRYEG+CV++ E+A+ + ++Y++ +V DG YG + +
Sbjct: 423 ILENPYLMLKGNHQEMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPEANG-T 481
Query: 474 WNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 533
W GMVGEL+ +AD+AVA LTIT RE+VIDFSKPFM+LGISI+ + KPG FSFLD
Sbjct: 482 WTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLD 541
Query: 534 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEE-FEEGRDQTTSDQSNEFGIFNSLW 592
P + +W+ ++ AY+ VS VLFLV+R +PYEW+S +GR N++ + NSLW
Sbjct: 542 PFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLV---NQYSLGNSLW 598
Query: 593 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 652
F +G FMQQG I+PR+LS R V GVWW FTLIIISSYTANLAAFLTV+RM PIES +D
Sbjct: 599 FPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDVPIESVDD 658
Query: 653 LAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKG 712
LA QT I YGT+ GS+ FF+ S+ +++MW YM S +PSVFV++TEEG+ RV S
Sbjct: 659 LADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNS-- 716
Query: 713 KYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGV 772
YA+LLESTMNEY QR C+ ++GG LD+KGYGI P GS R +LA+L+L E
Sbjct: 717 NYAFLLESTMNEYYRQRN-CNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNR 775
Query: 773 LDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKS 832
L+ LK KWW + G+C ++ + L + N+ G+F +LI GL +A+ +A++EF +
Sbjct: 776 LEILKRKWW-EGGKCPKEED---HRAKGLGMENIGGIFVVLICGLIVAIFMAMLEFLWTL 831
Query: 833 RSESKRMKGFC----------LIPQQSINEAIRTSTLP 860
R C ++ Q SI+ R + +P
Sbjct: 832 RHSEATEVSVCQEMVTELRSIILCQDSIHPRRRRAAVP 869
>gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3
precursor [Homo sapiens]
Length = 433
Score = 454 bits (1167), Expect = e-127
Identities = 218/413 (52%), Positives = 296/413 (71%), Gaps = 9/413 (2%)
Query: 10 TGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFAL-------SQLTEPPKLLPQIDIV 62
+GF G +GA FP+++QIGGLF QE+ AFR A+ + P L+P +D +
Sbjct: 13 SGFWGLAMGA-FPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNI 71
Query: 63 NISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFV 122
++SF +T FCSQ+S+GV+AIFG Y++R+V+ LTSFC ALH+ ITPSFP + +QFV
Sbjct: 72 ETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFV 131
Query: 123 LQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTE 182
LQLRP L+ AL+S++DHY+W FV++YD DRG S+LQ +++ A + W V+A+ + +
Sbjct: 132 LQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFND 191
Query: 183 EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNK 242
YR L ++L++++E+ V+DCE ERL IL QI+ + K+ GYHYI+ANLGF DI L +
Sbjct: 192 VSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLER 251
Query: 243 FKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAE 302
F GANVTGFQLV++ + K+M +WK D R++ + PKYTSALTYDGV VMAE
Sbjct: 252 FIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSE-TPPKYTSALTYDGVLVMAE 310
Query: 303 AFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRT 362
F+SLRRQ+IDISRRGNAGDCLANPA PWGQGID++R L+QVR +GLTGNVQF+ GRR
Sbjct: 311 TFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRV 370
Query: 363 NYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL 415
NYT+ V E+K G RK+GYWN+ DK V G D ++++NRT +VTTI+
Sbjct: 371 NYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIM 423
>gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3
precursor [Homo sapiens]
Length = 433
Score = 454 bits (1167), Expect = e-127
Identities = 218/413 (52%), Positives = 296/413 (71%), Gaps = 9/413 (2%)
Query: 10 TGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFAL-------SQLTEPPKLLPQIDIV 62
+GF G +GA FP+++QIGGLF QE+ AFR A+ + P L+P +D +
Sbjct: 13 SGFWGLAMGA-FPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNI 71
Query: 63 NISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFV 122
++SF +T FCSQ+S+GV+AIFG Y++R+V+ LTSFC ALH+ ITPSFP + +QFV
Sbjct: 72 ETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFV 131
Query: 123 LQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTE 182
LQLRP L+ AL+S++DHY+W FV++YD DRG S+LQ +++ A + W V+A+ + +
Sbjct: 132 LQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFND 191
Query: 183 EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNK 242
YR L ++L++++E+ V+DCE ERL IL QI+ + K+ GYHYI+ANLGF DI L +
Sbjct: 192 VSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLER 251
Query: 243 FKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAE 302
F GANVTGFQLV++ + K+M +WK D R++ + PKYTSALTYDGV VMAE
Sbjct: 252 FIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSE-TPPKYTSALTYDGVLVMAE 310
Query: 303 AFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRT 362
F+SLRRQ+IDISRRGNAGDCLANPA PWGQGID++R L+QVR +GLTGNVQF+ GRR
Sbjct: 311 TFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRV 370
Query: 363 NYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL 415
NYT+ V E+K G RK+GYWN+ DK V G D ++++NRT +VTTI+
Sbjct: 371 NYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIM 423
>gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens]
Length = 1007
Score = 354 bits (909), Expect = 2e-97
Identities = 235/870 (27%), Positives = 423/870 (48%), Gaps = 79/870 (9%)
Query: 19 ANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLP------QIDIVNISDSFEMTY 72
AN + I IG +F ++ FR A+ L + ++L + V+ ++ F+
Sbjct: 21 ANADSIIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQ 80
Query: 73 RFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHV----------------CFITPSFPVD 116
C ++G+ A+ + L S A+H+ C +T S +
Sbjct: 81 EACELMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRS---N 137
Query: 117 TSNQFVLQLRPE--LQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTA 174
++ + L +RP L D ++ ++ Y WQKF+ YD++ + +Q+ LD +++ V
Sbjct: 138 RNDDYTLSVRPPVYLHDVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVAL 197
Query: 175 VNILTTTEEGYRMLF-----QDLEKKKERL--VVVDCESERLNAILGQIIKLEKNGIGYH 227
+ + LF ++L + ++ L ++ + + ++++ H
Sbjct: 198 QKVENNINKMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFITEVVETNLVAFDCH 257
Query: 228 YILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDAR-DHTRVDWKRP 286
+I+ N D+D+ + ++ ++ T +P I Q+ + R T D K P
Sbjct: 258 WIIINEEINDVDVQELVRR--SIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDP 315
Query: 287 -----KYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRAL 341
+ ++ YD V ++A AF R S + C+ + PW G + +
Sbjct: 316 FAQNMEISNLYIYDTVLLLANAFHKKLEDRKWHSMASLS--CIRKNSKPWQGGRSMLETI 373
Query: 342 QQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHD-----GIRKIGYWNEDDKFVPAATDAQ 396
++ GLTG ++F E G N ++ + G+RK+G WN + TD +
Sbjct: 374 KKGGVSGLTGELEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKK 433
Query: 397 AGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRL 456
+ V R V T+LE+P+VM+ +N +Y+G+ +++ ++ ++G++Y +
Sbjct: 434 LENNMRGVVLR---VVTVLEEPFVMVSENV--LGKPKKYQGFSIDVLDALSNYLGFNYEI 488
Query: 457 EIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISI 516
+ D KYG+ D WNG+VGELV+ RAD+ ++ LTIT RE V+DF+ +M + +
Sbjct: 489 YVAPDHKYGSPQEDG-TWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGV 547
Query: 517 MIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQ 576
++++ +K+ +F+ L P +W CI + V ++++L++ +P + G
Sbjct: 548 LLRRAEKTVD-MFACLAPFDLSLWACIAGTVLLVGLLVYLLNWLNP-----PRLQMGSMT 601
Query: 577 TTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAA 636
+T+ ++NS+WF G+F+QQG ++ +L+ R++ G WW F LI+ISSYTANLAA
Sbjct: 602 STT-------LYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAA 654
Query: 637 FLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEK------MWTYMKS 690
FLT+ R+ S I+S +DL+KQTEI YGT+ + E R + FE+ MW +
Sbjct: 655 FLTITRIESSIQSLQDLSKQTEIPYGTVLDSAVYEHVRMKGLNPFERDSMYSQMWRMINR 714
Query: 691 AEPSVFVRTTEEGMIRVRKSK-GKYAYLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGI 748
+ S E ++K K G YA++ ++ + EY+ P C +G + +GYGI
Sbjct: 715 SNGS--ENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTIGNTVADRGYGI 772
Query: 749 ATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDS-GSKDKTSALSLSNVA 807
A GS R + +L+L + G +D LK KWW G+C S +K K AL + + A
Sbjct: 773 ALQHGSPYRDVFSQRILELQQNGDMDILKHKWWPKNGQCDLYSSVDTKQKGGALDIKSFA 832
Query: 808 GVFYILIGGLGLAMLVALIEFCYKSRSESK 837
GVF IL G+ L+ +A++E + R S+
Sbjct: 833 GVFCILAAGIVLSCFIAMLETWWNKRKGSR 862
>gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [Homo
sapiens]
Length = 1009
Score = 341 bits (874), Expect = 2e-93
Identities = 244/861 (28%), Positives = 409/861 (47%), Gaps = 80/861 (9%)
Query: 25 IQIGGLFPNQQSQEHAAFRFALSQLT------EPPKLLPQIDIVNISDSFEMTYRFCSQF 78
I IG +F +++ F+ A+S L+ + K+ I ++ ++ F+ C
Sbjct: 24 IHIGAIFEENAAKDDRVFQLAVSDLSLNDDILQSEKITYSIKVIEANNPFQAVQEACDLM 83
Query: 79 SKGVYAIFGFYERRTVNMLTSFCGALHV----------------CFITPSFPVDTSNQFV 122
++G+ A+ + N L S A+H+ C + PS +
Sbjct: 84 TQGILALVTSTGCASANALQSLTDAMHIPHLFVQRNPGGSPRTACHLNPS---PDGEAYT 140
Query: 123 LQLRP--ELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTT 180
L RP L D ++ ++ +WQKFV YD++ + LQ LD A+ V+ +
Sbjct: 141 LASRPPVRLNDVMLRLVTELRWQKFVMFYDSEYDIRGLQSFLDQASRLGLDVSLQKVDKN 200
Query: 181 TEEGYRMLF-----QDLEKKKERL--VVVDCESERLNAILGQIIKLEKNGIGYHYILANL 233
+ LF ++L + ++ L ++ + ++ + + ++ H++ N
Sbjct: 201 ISHVFTSLFTTMKTEELNRYRDTLRRAILLLSPQGAHSFINEAVETNLASKDSHWVFVNE 260
Query: 234 GFMDIDLNKFKESGANVTGFQLVNYTDTIP-AKIMQQWKNSDARDHTRVDWKRPKYTSAL 292
D ++ S ++ P AK Q+ ++ R + + + Y L
Sbjct: 261 EISDPEILDLVHSALG----RMTVVRQIFPSAKDNQKCTRNNHRISSLLCDPQEGYLQML 316
Query: 293 T------YDGVKVMAEAFQSLRRQRIDISRRGNAG-DCLANPAVPWGQGIDIQRALQQVR 345
YD V ++A AF R+ D A +C+ PW G + +++
Sbjct: 317 QISNLYLYDSVLMLANAFH---RKLEDRKWHSMASLNCIRKSTKPWNGGRSMLDTIKKGH 373
Query: 346 FEGLTGNVQFNEKGRRTNYTLHVIEMKHD-----GIRKIGYWNEDDKFVPAATDAQAGGD 400
GLTG ++F E ++ + +RK+ W+ + + + G
Sbjct: 374 ITGLTGVMEFREDSSNPYVQFEILGTTYSETFGKDMRKLATWDSEKGLNGSLQERPMG-- 431
Query: 401 NSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVS 460
S +Q T V T+LE+P+VM+ +N RY+G+ +++ +AK +G+ Y +
Sbjct: 432 -SRLQGLTLKVVTVLEEPFVMVAENI--LGQPKRYKGFSIDVLDALAKALGFKYEIYQAP 488
Query: 461 DGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 520
DG+YG + +T +WNGM+GEL+ RAD+A++ +TIT RE V+DFSK +M + I+IKK
Sbjct: 489 DGRYGHQLHNT-SWNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYSVGILIKK 547
Query: 521 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSD 580
P++ K +FS P + +W CI A V V++F+++R S T
Sbjct: 548 PEE-KISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVRAQSAAQPRPSASAT-- 604
Query: 581 QSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 640
+ +++W GAF+QQG + S S++ RIV G WW FTLI+ SSYTANLAAFLTV
Sbjct: 605 ------LHSAIWIVYGAFVQQGGESSVNSMAMRIVMGSWWLFTLIVCSSYTANLAAFLTV 658
Query: 641 ERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRR------SKIAVFEKMW-TYMKSAEP 693
RM +PI + +DL+KQ E++YGT+ + E+FR + + F ++W T K+
Sbjct: 659 SRMDNPIRTFQDLSKQVEMSYGTVRDSAVYEYFRAKGTNPLEQDSTFAELWRTISKNGGA 718
Query: 694 SVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIE-QRKPCDTMKVGGNLDSKGYGIATPK 752
V + EG+ + + KG YA+L + + EY C +G ++ SKGYGIA
Sbjct: 719 DNCVSSPSEGIRKAK--KGNYAFLWDVAVVEYAALTDDDCSVTVIGNSISSKGYGIALQH 776
Query: 753 GSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECG-SKDSGSKDKTSALSLSNVAGVFY 811
GS R + +L+L + G LD LK KWW G C + + ++ +L L + AGVF
Sbjct: 777 GSPYRDLFSQRILELQDTGDLDVLKQKWWPHMGRCDLTSHASAQADGKSLKLHSFAGVFC 836
Query: 812 ILIGGLGLAMLVALIEFCYKS 832
IL GL LA LVA +E + S
Sbjct: 837 ILAIGLLLACLVAALELWWNS 857
>gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens]
Length = 885
Score = 244 bits (622), Expect = 3e-64
Identities = 197/751 (26%), Positives = 349/751 (46%), Gaps = 115/751 (15%)
Query: 140 YKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTE--EGYRMLFQDLEKKKE 197
Y W + + D QK L+T E+ + A +L + L + ++ +
Sbjct: 158 YSWNHIILLVSDDHEGRAAQKRLETLLEER-ESKAEKVLQFDPGTKNVTALLMEAKELEA 216
Query: 198 RLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVN 257
R++++ + + L G GY +++ G +I N + + + G QL+N
Sbjct: 217 RVIILSASEDDAATVYRAAAMLNMTGSGYVWLV---GEREISGNALRYAPDGILGLQLIN 273
Query: 258 YTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSL-RRQRIDISR 316
K SA D V V+A+A L ++ I
Sbjct: 274 ----------------------------GKNESAHISDAVGVVAQAVHELLEKENITDPP 305
Query: 317 RGNAGDCLANPAVPWGQGIDIQRALQQVRF-EGLTGNVQFNEKGRRTNYTLHVIEMKHDG 375
RG C+ N + W G +R L ++ +G+TG V+FNE G R ++ +++
Sbjct: 306 RG----CVGNTNI-WKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRK 360
Query: 376 IRKIGYWN------EDDKFV-PAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQ 428
+ ++G +N D K + P + G S + + + TI ++P+V +K +
Sbjct: 361 LVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLK---IVTIHQEPFVYVKPTLSD 417
Query: 429 -------------------------FEGNDRYE------GYCVELAAEIAKHVGYSYRLE 457
G+ R+ G+C++L ++A+ + ++Y +
Sbjct: 418 GTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTYEVH 477
Query: 458 IVSDGKYGARD----PDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLG 513
+V+DGK+G ++ + K WNGM+GEL+ G+AD+ VAPLTI R + I+FSKPF G
Sbjct: 478 LVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQG 537
Query: 514 ISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEG 573
++I++KK + + + SF+ P +W+ + + V+V+L+L+ RFSP+ G
Sbjct: 538 LTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPF---------G 587
Query: 574 RDQTTSDQSNE--FGIFNSLWFSLGAFMQQGC-DISPRSLSGRIVGGVWWFFTLIIISSY 630
R + S++ E + +++WFS G + G + +PRS S RI+G VW F +II++SY
Sbjct: 588 RFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASY 647
Query: 631 TANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLEAGSTKEFFRRSKIAVFEKMWTY 687
TANLAAFL ++R I D + + Y T++ S +FRR M+ +
Sbjct: 648 TANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQ--VELSTMYRH 705
Query: 688 MKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYG 747
M+ + E + VR +K +A++ +S + E+ E + CD + G G+G
Sbjct: 706 MEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF-EASQKCDLVTTGELFFRSGFG 759
Query: 748 IATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVA 807
I K S + V+L++LK E G ++ L K W EC S+ + + L+ N+A
Sbjct: 760 IGMRKDSPWKQNVSLSILKSHENGFMEDL-DKTWVRYQECDSRSNA----PATLTFENMA 814
Query: 808 GVFYILIGGLGLAMLVALIEFCYKSRSESKR 838
GVF ++ GG+ + + IE YK +++R
Sbjct: 815 GVFMLVAGGIVAGIFLIFIEIAYKRHKDARR 845
>gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens]
Length = 938
Score = 244 bits (622), Expect = 3e-64
Identities = 197/751 (26%), Positives = 349/751 (46%), Gaps = 115/751 (15%)
Query: 140 YKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTE--EGYRMLFQDLEKKKE 197
Y W + + D QK L+T E+ + A +L + L + ++ +
Sbjct: 158 YSWNHIILLVSDDHEGRAAQKRLETLLEER-ESKAEKVLQFDPGTKNVTALLMEAKELEA 216
Query: 198 RLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVN 257
R++++ + + L G GY +++ G +I N + + + G QL+N
Sbjct: 217 RVIILSASEDDAATVYRAAAMLNMTGSGYVWLV---GEREISGNALRYAPDGILGLQLIN 273
Query: 258 YTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSL-RRQRIDISR 316
K SA D V V+A+A L ++ I
Sbjct: 274 ----------------------------GKNESAHISDAVGVVAQAVHELLEKENITDPP 305
Query: 317 RGNAGDCLANPAVPWGQGIDIQRALQQVRF-EGLTGNVQFNEKGRRTNYTLHVIEMKHDG 375
RG C+ N + W G +R L ++ +G+TG V+FNE G R ++ +++
Sbjct: 306 RG----CVGNTNI-WKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRK 360
Query: 376 IRKIGYWN------EDDKFV-PAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQ 428
+ ++G +N D K + P + G S + + + TI ++P+V +K +
Sbjct: 361 LVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLK---IVTIHQEPFVYVKPTLSD 417
Query: 429 -------------------------FEGNDRYE------GYCVELAAEIAKHVGYSYRLE 457
G+ R+ G+C++L ++A+ + ++Y +
Sbjct: 418 GTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTYEVH 477
Query: 458 IVSDGKYGARD----PDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLG 513
+V+DGK+G ++ + K WNGM+GEL+ G+AD+ VAPLTI R + I+FSKPF G
Sbjct: 478 LVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQG 537
Query: 514 ISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEG 573
++I++KK + + + SF+ P +W+ + + V+V+L+L+ RFSP+ G
Sbjct: 538 LTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPF---------G 587
Query: 574 RDQTTSDQSNE--FGIFNSLWFSLGAFMQQGC-DISPRSLSGRIVGGVWWFFTLIIISSY 630
R + S++ E + +++WFS G + G + +PRS S RI+G VW F +II++SY
Sbjct: 588 RFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASY 647
Query: 631 TANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLEAGSTKEFFRRSKIAVFEKMWTY 687
TANLAAFL ++R I D + + Y T++ S +FRR M+ +
Sbjct: 648 TANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQ--VELSTMYRH 705
Query: 688 MKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYG 747
M+ + E + VR +K +A++ +S + E+ E + CD + G G+G
Sbjct: 706 MEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF-EASQKCDLVTTGELFFRSGFG 759
Query: 748 IATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVA 807
I K S + V+L++LK E G ++ L K W EC S+ + + L+ N+A
Sbjct: 760 IGMRKDSPWKQNVSLSILKSHENGFMEDL-DKTWVRYQECDSRSNA----PATLTFENMA 814
Query: 808 GVFYILIGGLGLAMLVALIEFCYKSRSESKR 838
GVF ++ GG+ + + IE YK +++R
Sbjct: 815 GVFMLVAGGIVAGIFLIFIEIAYKRHKDARR 845
>gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens]
Length = 901
Score = 244 bits (622), Expect = 3e-64
Identities = 197/751 (26%), Positives = 349/751 (46%), Gaps = 115/751 (15%)
Query: 140 YKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTE--EGYRMLFQDLEKKKE 197
Y W + + D QK L+T E+ + A +L + L + ++ +
Sbjct: 158 YSWNHIILLVSDDHEGRAAQKRLETLLEER-ESKAEKVLQFDPGTKNVTALLMEAKELEA 216
Query: 198 RLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVN 257
R++++ + + L G GY +++ G +I N + + + G QL+N
Sbjct: 217 RVIILSASEDDAATVYRAAAMLNMTGSGYVWLV---GEREISGNALRYAPDGILGLQLIN 273
Query: 258 YTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSL-RRQRIDISR 316
K SA D V V+A+A L ++ I
Sbjct: 274 ----------------------------GKNESAHISDAVGVVAQAVHELLEKENITDPP 305
Query: 317 RGNAGDCLANPAVPWGQGIDIQRALQQVRF-EGLTGNVQFNEKGRRTNYTLHVIEMKHDG 375
RG C+ N + W G +R L ++ +G+TG V+FNE G R ++ +++
Sbjct: 306 RG----CVGNTNI-WKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRK 360
Query: 376 IRKIGYWN------EDDKFV-PAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQ 428
+ ++G +N D K + P + G S + + + TI ++P+V +K +
Sbjct: 361 LVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLK---IVTIHQEPFVYVKPTLSD 417
Query: 429 -------------------------FEGNDRYE------GYCVELAAEIAKHVGYSYRLE 457
G+ R+ G+C++L ++A+ + ++Y +
Sbjct: 418 GTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTYEVH 477
Query: 458 IVSDGKYGARD----PDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLG 513
+V+DGK+G ++ + K WNGM+GEL+ G+AD+ VAPLTI R + I+FSKPF G
Sbjct: 478 LVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQG 537
Query: 514 ISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEG 573
++I++KK + + + SF+ P +W+ + + V+V+L+L+ RFSP+ G
Sbjct: 538 LTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPF---------G 587
Query: 574 RDQTTSDQSNE--FGIFNSLWFSLGAFMQQGC-DISPRSLSGRIVGGVWWFFTLIIISSY 630
R + S++ E + +++WFS G + G + +PRS S RI+G VW F +II++SY
Sbjct: 588 RFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASY 647
Query: 631 TANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLEAGSTKEFFRRSKIAVFEKMWTY 687
TANLAAFL ++R I D + + Y T++ S +FRR M+ +
Sbjct: 648 TANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQ--VELSTMYRH 705
Query: 688 MKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYG 747
M+ + E + VR +K +A++ +S + E+ E + CD + G G+G
Sbjct: 706 MEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF-EASQKCDLVTTGELFFRSGFG 759
Query: 748 IATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVA 807
I K S + V+L++LK E G ++ L K W EC S+ + + L+ N+A
Sbjct: 760 IGMRKDSPWKQNVSLSILKSHENGFMEDL-DKTWVRYQECDSRSNA----PATLTFENMA 814
Query: 808 GVFYILIGGLGLAMLVALIEFCYKSRSESKR 838
GVF ++ GG+ + + IE YK +++R
Sbjct: 815 GVFMLVAGGIVAGIFLIFIEIAYKRHKDARR 845
>gi|55770854 N-methyl-D-aspartate receptor subunit 2C precursor
[Homo sapiens]
Length = 1233
Score = 196 bits (498), Expect = 8e-50
Identities = 198/788 (25%), Positives = 340/788 (43%), Gaps = 99/788 (12%)
Query: 79 SKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQDALISIID 138
++ V I F +T + S G V +TP P Q + L +LQ L +++
Sbjct: 101 TEAVAQILDFISSQTHVPILSISGGSAVV-LTPKEPGSAFLQLGVSLEQQLQ-VLFKVLE 158
Query: 139 HYKWQKFVYIYDADRG----LSVLQKVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEK 194
Y W F I G L ++ V D A+ +W++ V L G R Q L +
Sbjct: 159 EYDWSAFAVITSLHPGHALFLEGVRAVAD-ASHVSWRLLDVVTLELGPGGPRARTQRLLR 217
Query: 195 KKERLVVVD-CESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGF 253
+ + V V C E + + + G G+ +++ NL D
Sbjct: 218 QLDAPVFVAYCSREEAEVLFAEAAQAGLVGPGHVWLVPNLALGSTDAPP----------- 266
Query: 254 QLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRID 313
+ + + + + W+ S R R DGV ++A S RQ
Sbjct: 267 --ATFPVGLISVVTESWRLS-LRQKVR--------------DGVAILALGAHSYWRQHGT 309
Query: 314 ISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEM-K 372
+ AGDC +P R L V +EG + F+ G T+ VI + +
Sbjct: 310 LP--APAGDCRVHPGPVSPAREAFYRHLLNVTWEGR--DFSFSPGGYLVQPTMVVIALNR 365
Query: 373 HDGIRKIGYWNEDDKFVPAATDAQAGGD-NSSVQNRTYIVTTILEDPYVML--------- 422
H +G W ++ + V +R V T+ E P+V++
Sbjct: 366 HRLWEMVGRWEHGVLYMKYPVWPRYSASLQPVVDSRHLTVATLEERPFVIVESPDPGTGG 425
Query: 423 ---------KKNANQFEGNDRY-------EGYCVELAAEIAKHVGYSYRLEIVSDGKYGA 466
+++ + F D +G+C+++ ++A+ V +SY L +V++GK+G
Sbjct: 426 CVPNTVPCRRQSNHTFSSGDVAPYTKLCCKGFCIDILKKLARVVKFSYDLYLVTNGKHGK 485
Query: 467 RDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKP 526
R WNGM+GE+ Y RAD+A+ LTI R E++DFS PF+ GIS+M+ +
Sbjct: 486 RVRGV--WNGMIGEVYYKRADMAIGSLTINEERSEIVDFSVPFVETGISVMVAR-SNGTV 542
Query: 527 GVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEF 585
+FL+P + +W M V V++ +F+ FSP +++ G+ F
Sbjct: 543 SPSAFLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVS-YNQNLTRGK----KSGGPAF 597
Query: 586 GIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV 644
I S+W I +PR + +I+ VW FF +I ++SYTANLAAF+ E+ +
Sbjct: 598 TIGKSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYI 657
Query: 645 SPIESAEDLAKQ------TEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVR 698
+ D Q +GT+ GST+ R + + M T+M R
Sbjct: 658 DTVSGLSDKKFQRPQDQYPPFRFGTVPNGSTERNIRSN----YRDMHTHMVKFNQ----R 709
Query: 699 TTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGIATPKGSA 755
+ E+ + ++ K A++ ++ + Y+ + + C + +G + GYGIA K S
Sbjct: 710 SVEDALTSLKMGK-LDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSH 768
Query: 756 LRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIG 815
+ ++LA+L+ G KL++ W G C ++ ++ +S L + N+AGVFY+L+
Sbjct: 769 WKRAIDLALLQFLGDGETQKLETVWL--SGIC--QNEKNEVMSSKLDIDNMAGVFYMLLV 824
Query: 816 GLGLAMLV 823
+GLA+LV
Sbjct: 825 AMGLALLV 832
>gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor
[Homo sapiens]
Length = 1484
Score = 189 bits (481), Expect = 8e-48
Identities = 186/757 (24%), Positives = 337/757 (44%), Gaps = 102/757 (13%)
Query: 116 DTSNQFVLQLRPELQD---ALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKN--- 169
D S+ F Q P ++ +++I++ Y W F + G + + E +
Sbjct: 138 DESSMF-FQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVG 196
Query: 170 WQVTAVNILTTT-EEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHY 228
W++ V +L + ++G + L+K + ++++ C E I + G GY +
Sbjct: 197 WELEEVLLLDMSLDDGDSKIQNQLKKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTW 256
Query: 229 ILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKY 288
I+ +L D TDT+PA+ + + D+ P
Sbjct: 257 IVPSLVAGD---------------------TDTVPAEFPT---GLISVSYDEWDYGLP-- 290
Query: 289 TSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEG 348
A DG+ ++ A + + I ++ C Q + R L V FEG
Sbjct: 291 --ARVRDGIAIITTAASDMLSEHSFIPEPKSS--CYNTHEKRIYQSNMLNRYLINVTFEG 346
Query: 349 LTGNVQFNEKGRRTNYTLHVIEM-KHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNR 407
N+ F+E G + + L +I + K ++G W + + + + ++
Sbjct: 347 R--NLSFSEDGYQMHPKLVIILLNKERKWERVGKWKDKSLQMKYYVWPRMCPETEEQEDD 404
Query: 408 TYIVTTILEDPYVMLKK--------------------NANQFEGNDRY-----EGYCVEL 442
+ T+ E P+V+++ N+ + Y +G+C+++
Sbjct: 405 HLSIVTLEEAPFVIVESVDPLSGTCMRNTVPCQKRIVTENKTDEEPGYIKKCCKGFCIDI 464
Query: 443 AAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEV 502
+I+K V ++Y L +V++GK+G + T WNGM+GE+V RA +AV LTI R EV
Sbjct: 465 LKKISKSVKFTYDLYLVTNGKHGKKINGT--WNGMIGEVVMKRAYMAVGSLTINEERSEV 522
Query: 503 IDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFS 561
+DFS PF+ GIS+M+ + +FL+P + ++W M V I +V +F+ FS
Sbjct: 523 VDFSVPFIETGISVMVSR-SNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFS 581
Query: 562 PYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVWW 620
P ++ +GR+ F I ++W G + +P+ + +I+ VW
Sbjct: 582 PV-GYNRCLADGRE----PGGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWA 636
Query: 621 FFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLEAGSTKEFFR 674
FF +I ++SYTANLAAF+ E V + D Q +GT+ GST+ R
Sbjct: 637 FFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIR 696
Query: 675 RSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-KPCD 733
+ + +M YM R ++ ++ ++ K A++ ++ + Y+ R + C
Sbjct: 697 NN----YAEMHAYMGKFNQ----RGVDDALLSLKTGK-LDAFIYDAAVLNYMAGRDEGCK 747
Query: 734 TMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKD 791
+ +G S GYGIA K S + V+LA+L+L G +++L++ W G C ++
Sbjct: 748 LVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWL--TGICHNEK 805
Query: 792 SGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEF 828
++ +S L + N+AGVFY+ LG AM ++LI F
Sbjct: 806 --NEVMSSQLDIDNMAGVFYM----LGAAMALSLITF 836
>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor
[Homo sapiens]
Length = 1336
Score = 179 bits (454), Expect = 1e-44
Identities = 153/570 (26%), Positives = 267/570 (46%), Gaps = 72/570 (12%)
Query: 296 GVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQF 355
GV V+A Q+L R + G+ DC A G+ + R + ++ + F
Sbjct: 323 GVAVVARGAQALLRDYGFLPELGH--DCRAQNRTHRGESL--HRYFMNITWDNR--DYSF 376
Query: 356 NEKGRRTNYTLHVIEMKHDGIRKI-GYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTI 414
NE G N +L VI + D ++ G W + + ++ G V + ++
Sbjct: 377 NEDGFLVNPSLVVISLTRDRTWEVVGSWEQQTLRLKYPLWSRYGRFLQPVDDTQHLTVAT 436
Query: 415 LEDPYVMLKKNANQFEGN----------------------DRYE-----GYCVELAAEIA 447
LE+ ++ + A+ G R E G+C+++ +A
Sbjct: 437 LEERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPEKRCCKGFCIDILKRLA 496
Query: 448 KHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSK 507
+G+SY L +V++GK+G + WNGM+GE+ Y RAD+A+ LTI R E++DFS
Sbjct: 497 HTIGFSYDLYLVTNGKHGKKIDGV--WNGMIGEVFYQRADMAIGSLTINEERSEIVDFSV 554
Query: 508 PFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWH 566
PF+ GIS+M+ + +FL+P + +W M V V+V +F+ SP ++
Sbjct: 555 PFVETGISVMVAR-SNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVGYN 613
Query: 567 SEEFEEGRDQTTSDQ--SNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVWWFFT 623
R T + + F I S+W + +PR + +I+ VW FF
Sbjct: 614 -------RSLATGKRPGGSTFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFA 666
Query: 624 LIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLEAGSTKEFFRRSK 677
+I ++SYTANLAAF+ E V + D Q + +GT+ GST++ R +
Sbjct: 667 VIFLASYTANLAAFMIQEEYVDTVSGLSDRKFQRPQEQYPPLKFGTVPNGSTEKNIRSN- 725
Query: 678 IAVFEKMWTYM-KSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-KPCDTM 735
+ M +YM + +P V EE + +++ K A++ ++ + Y+ ++ + C +
Sbjct: 726 ---YPDMHSYMVRYNQPRV-----EEALTQLKAGK-LDAFIYDAAVLNYMARKDEGCKLV 776
Query: 736 KVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSG 793
+G + GYGIA KGS + P++LA+L+ ++ L+ W G C +
Sbjct: 777 TIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEMLERLWL--SGIC--HNDK 832
Query: 794 SKDKTSALSLSNVAGVFYILIGGLGLAMLV 823
+ +S L + N+AGVFY+L+ +GL++LV
Sbjct: 833 IEVMSSKLDIDNMAGVFYMLLVAMGLSLLV 862
>gi|197313638 N-methyl-D-aspartate receptor subunit 2A isoform 2
precursor [Homo sapiens]
Length = 1281
Score = 177 bits (450), Expect = 3e-44
Identities = 176/760 (23%), Positives = 330/760 (43%), Gaps = 101/760 (13%)
Query: 114 PVDTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKN---W 170
P T QF ++ + ++ I+ Y W F + G + T + + W
Sbjct: 140 PTSTFFQFGASIQQQAT-VMLKIMQDYDWHVFSLVTTIFPGYREFISFVKTTVDNSFVGW 198
Query: 171 QVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYIL 230
+ V L T+ E + Q L+K ++++ C + IL + L G + +I+
Sbjct: 199 DMQNVITLDTSFEDAKTQVQ-LKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIV 257
Query: 231 ANL--GFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKY 288
+L G ++ +F +G V+Y D W S
Sbjct: 258 PSLVSGNTELIPKEFP------SGLISVSYDD---------WDYS--------------- 287
Query: 289 TSALTYDGVKVMAEAFQSLRRQRIDISR-RGNAGDCLANPAVPWGQGIDIQRALQQVRFE 347
A DG+ ++ A S+ + I + + + P VP + + V ++
Sbjct: 288 LEARVRDGIGILTTAASSMLEKFSYIPEAKASCYGQMERPEVPMHT---LHPFMVNVTWD 344
Query: 348 GLTGNVQFNEKGRRTNYTLHVIEMKHDGI-RKIGYWNEDDKFVPAA--------TDAQAG 398
G ++ F E+G + + L VI + D K+G W + A +D +
Sbjct: 345 GK--DLSFTEEGYQVHPRLVVIVLNKDREWEKVGKWENHTLSLRHAVWPRYKSFSDCEPD 402
Query: 399 GDNSSVQNRTYIVTTILED----------------PYVMLKKNANQFEGNDRY-EGYCVE 441
++ S+ I+ED +V + + N+ + +G+C++
Sbjct: 403 DNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCID 462
Query: 442 LAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREE 501
+ ++++ V ++Y L +V++GK+G + WNGM+GE+VY RA +AV LTI R E
Sbjct: 463 ILKKLSRTVKFTYDLYLVTNGKHGKKV--NNVWNGMIGEVVYQRAVMAVGSLTINEERSE 520
Query: 502 VIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRF 560
V+DFS PF+ GIS+M+ + +FL+P + +W M V I ++ +F+ F
Sbjct: 521 VVDFSVPFVETGISVMVSR-SNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYF 579
Query: 561 SPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVW 619
SP ++ +G+ + F I ++W G + +P+ + +I+ VW
Sbjct: 580 SPV-GYNRNLAKGK----APHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVW 634
Query: 620 WFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLEAGSTKEFF 673
FF +I ++SYTANLAAF+ E V + D Q +GT+ GST+
Sbjct: 635 AFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNI 694
Query: 674 RRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-KPC 732
R + + YM + E+ ++ ++ K A++ ++ + Y R + C
Sbjct: 695 RNN--------YPYMHQYMTKFNQKGVEDALVSLKTGK-LDAFIYDAAVLNYKAGRDEGC 745
Query: 733 DTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSK 790
+ +G + GYGIA KGS + ++LA+L+ G +++L++ W G C ++
Sbjct: 746 KLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWL--TGICHNE 803
Query: 791 DSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCY 830
++ +S L + N+AGVFY+L + L+++ + E +
Sbjct: 804 K--NEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLF 841
>gi|197313636 N-methyl-D-aspartate receptor subunit 2A isoform 1
precursor [Homo sapiens]
Length = 1464
Score = 177 bits (450), Expect = 3e-44
Identities = 176/760 (23%), Positives = 330/760 (43%), Gaps = 101/760 (13%)
Query: 114 PVDTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKN---W 170
P T QF ++ + ++ I+ Y W F + G + T + + W
Sbjct: 140 PTSTFFQFGASIQQQAT-VMLKIMQDYDWHVFSLVTTIFPGYREFISFVKTTVDNSFVGW 198
Query: 171 QVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYIL 230
+ V L T+ E + Q L+K ++++ C + IL + L G + +I+
Sbjct: 199 DMQNVITLDTSFEDAKTQVQ-LKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIV 257
Query: 231 ANL--GFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKY 288
+L G ++ +F +G V+Y D W S
Sbjct: 258 PSLVSGNTELIPKEFP------SGLISVSYDD---------WDYS--------------- 287
Query: 289 TSALTYDGVKVMAEAFQSLRRQRIDISR-RGNAGDCLANPAVPWGQGIDIQRALQQVRFE 347
A DG+ ++ A S+ + I + + + P VP + + V ++
Sbjct: 288 LEARVRDGIGILTTAASSMLEKFSYIPEAKASCYGQMERPEVPMHT---LHPFMVNVTWD 344
Query: 348 GLTGNVQFNEKGRRTNYTLHVIEMKHDGI-RKIGYWNEDDKFVPAA--------TDAQAG 398
G ++ F E+G + + L VI + D K+G W + A +D +
Sbjct: 345 GK--DLSFTEEGYQVHPRLVVIVLNKDREWEKVGKWENHTLSLRHAVWPRYKSFSDCEPD 402
Query: 399 GDNSSVQNRTYIVTTILED----------------PYVMLKKNANQFEGNDRY-EGYCVE 441
++ S+ I+ED +V + + N+ + +G+C++
Sbjct: 403 DNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCID 462
Query: 442 LAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREE 501
+ ++++ V ++Y L +V++GK+G + WNGM+GE+VY RA +AV LTI R E
Sbjct: 463 ILKKLSRTVKFTYDLYLVTNGKHGKKV--NNVWNGMIGEVVYQRAVMAVGSLTINEERSE 520
Query: 502 VIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRF 560
V+DFS PF+ GIS+M+ + +FL+P + +W M V I ++ +F+ F
Sbjct: 521 VVDFSVPFVETGISVMVSR-SNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYF 579
Query: 561 SPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVW 619
SP ++ +G+ + F I ++W G + +P+ + +I+ VW
Sbjct: 580 SPV-GYNRNLAKGK----APHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVW 634
Query: 620 WFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLEAGSTKEFF 673
FF +I ++SYTANLAAF+ E V + D Q +GT+ GST+
Sbjct: 635 AFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNI 694
Query: 674 RRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-KPC 732
R + + YM + E+ ++ ++ K A++ ++ + Y R + C
Sbjct: 695 RNN--------YPYMHQYMTKFNQKGVEDALVSLKTGK-LDAFIYDAAVLNYKAGRDEGC 745
Query: 733 DTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSK 790
+ +G + GYGIA KGS + ++LA+L+ G +++L++ W G C ++
Sbjct: 746 KLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWL--TGICHNE 803
Query: 791 DSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCY 830
++ +S L + N+AGVFY+L + L+++ + E +
Sbjct: 804 K--NEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLF 841
>gi|4504125 N-methyl-D-aspartate receptor subunit 2A isoform 1
precursor [Homo sapiens]
Length = 1464
Score = 177 bits (450), Expect = 3e-44
Identities = 176/760 (23%), Positives = 330/760 (43%), Gaps = 101/760 (13%)
Query: 114 PVDTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKN---W 170
P T QF ++ + ++ I+ Y W F + G + T + + W
Sbjct: 140 PTSTFFQFGASIQQQAT-VMLKIMQDYDWHVFSLVTTIFPGYREFISFVKTTVDNSFVGW 198
Query: 171 QVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYIL 230
+ V L T+ E + Q L+K ++++ C + IL + L G + +I+
Sbjct: 199 DMQNVITLDTSFEDAKTQVQ-LKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIV 257
Query: 231 ANL--GFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKY 288
+L G ++ +F +G V+Y D W S
Sbjct: 258 PSLVSGNTELIPKEFP------SGLISVSYDD---------WDYS--------------- 287
Query: 289 TSALTYDGVKVMAEAFQSLRRQRIDISR-RGNAGDCLANPAVPWGQGIDIQRALQQVRFE 347
A DG+ ++ A S+ + I + + + P VP + + V ++
Sbjct: 288 LEARVRDGIGILTTAASSMLEKFSYIPEAKASCYGQMERPEVPMHT---LHPFMVNVTWD 344
Query: 348 GLTGNVQFNEKGRRTNYTLHVIEMKHDGI-RKIGYWNEDDKFVPAA--------TDAQAG 398
G ++ F E+G + + L VI + D K+G W + A +D +
Sbjct: 345 GK--DLSFTEEGYQVHPRLVVIVLNKDREWEKVGKWENHTLSLRHAVWPRYKSFSDCEPD 402
Query: 399 GDNSSVQNRTYIVTTILED----------------PYVMLKKNANQFEGNDRY-EGYCVE 441
++ S+ I+ED +V + + N+ + +G+C++
Sbjct: 403 DNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCID 462
Query: 442 LAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREE 501
+ ++++ V ++Y L +V++GK+G + WNGM+GE+VY RA +AV LTI R E
Sbjct: 463 ILKKLSRTVKFTYDLYLVTNGKHGKKV--NNVWNGMIGEVVYQRAVMAVGSLTINEERSE 520
Query: 502 VIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRF 560
V+DFS PF+ GIS+M+ + +FL+P + +W M V I ++ +F+ F
Sbjct: 521 VVDFSVPFVETGISVMVSR-SNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYF 579
Query: 561 SPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVW 619
SP ++ +G+ + F I ++W G + +P+ + +I+ VW
Sbjct: 580 SPV-GYNRNLAKGK----APHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVW 634
Query: 620 WFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLEAGSTKEFF 673
FF +I ++SYTANLAAF+ E V + D Q +GT+ GST+
Sbjct: 635 AFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNI 694
Query: 674 RRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQR-KPC 732
R + + YM + E+ ++ ++ K A++ ++ + Y R + C
Sbjct: 695 RNN--------YPYMHQYMTKFNQKGVEDALVSLKTGK-LDAFIYDAAVLNYKAGRDEGC 745
Query: 733 DTMKVGGN--LDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSK 790
+ +G + GYGIA KGS + ++LA+L+ G +++L++ W G C ++
Sbjct: 746 KLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWL--TGICHNE 803
Query: 791 DSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCY 830
++ +S L + N+AGVFY+L + L+++ + E +
Sbjct: 804 K--NEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLF 841
>gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
[Homo sapiens]
Length = 1043
Score = 159 bits (402), Expect = 1e-38
Identities = 122/431 (28%), Positives = 206/431 (47%), Gaps = 34/431 (7%)
Query: 437 GYCVELAAEIAKHVGYSYRLEIVSDGKYGA-RDPDTKAWNGMVGELVYGRADVAVAPLTI 495
GYC++L +A+ + + L +V DGKYGA RD W G+VG+L+ GRA +AV +I
Sbjct: 478 GYCIDLLERLAEDTPFDFELYLVGDGKYGALRDG---RWTGLVGDLLAGRAHMAVTSFSI 534
Query: 496 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLF 555
R +V+DF+ PF S + IM++ + P + +F+ PL + W +GV L
Sbjct: 535 NSARSQVVDFTSPFFSTSLGIMVRARDTASP-IGAFMWPLHWSTW-------LGVFAALH 586
Query: 556 LVSRF-SPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRI 614
L + F + YEW S R + S + N + L F + +P+ +GR+
Sbjct: 587 LTALFLTVYEWRSPYGLTPRGRNRSTVFSYSSALNLCYAIL--FRRTVSSKTPKCPTGRL 644
Query: 615 VGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLA---KQTEIAYGTLEAGSTKE 671
+ +W F L+++SSYTANLAA + ++ + D +GT+ S +
Sbjct: 645 LMNLWAIFCLLVLSSYTANLAAVMVGDKTFEELSGIHDPKLHHPAQGFRFGTVWESSAEA 704
Query: 672 FFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKY-AYLLESTMNEY-IEQR 729
+ ++S F M +M+ TT G+ + K A++++ ++ +Y +
Sbjct: 705 YIKKS----FPDMHAHMRRHS----APTTPRGVAMLTSDPPKLNAFIMDKSLLDYEVSID 756
Query: 730 KPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGS 789
C + VG +GYGI P+ S L ++ + + G +D L K WY CG
Sbjct: 757 ADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDK-WYKMVPCG- 814
Query: 790 KDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKG----FCLI 845
K + +T +S+ + AG+F +L GLG A+L +L E + + + KG + L
Sbjct: 815 KRVFAVTETLQMSIYHFAGLFVLLCLGLGSALLSSLGEHAFFRLALPRIRKGSRLQYWLH 874
Query: 846 PQQSINEAIRT 856
Q I+ A+ T
Sbjct: 875 TSQKIHRALNT 885
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,894,946
Number of Sequences: 37866
Number of extensions: 1356199
Number of successful extensions: 3621
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 3430
Number of HSP's gapped (non-prelim): 48
length of query: 906
length of database: 18,247,518
effective HSP length: 111
effective length of query: 795
effective length of database: 14,044,392
effective search space: 11165291640
effective search space used: 11165291640
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.