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Search of human proteins with 166795264
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
(517 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|166795264 AE binding protein 2 isoform b [Homo sapiens] 1040 0.0
gi|166795262 AE binding protein 2 isoform a [Homo sapiens] 1013 0.0
gi|4885279 GLI family zinc finger 1 isoform 1 [Homo sapiens] 81 3e-15
gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens] 80 4e-15
gi|109637784 GLIS family zinc finger 3 isoform a [Homo sapiens] 76 8e-14
gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens] 76 8e-14
gi|166706915 GLIS family zinc finger 1 [Homo sapiens] 73 7e-13
gi|22748877 basic helix-loop-helix domain containing, class B, 5... 72 1e-12
gi|195972866 keratin 10 [Homo sapiens] 72 2e-12
gi|51173735 ras responsive element binding protein 1 isoform 2 [... 71 3e-12
gi|51173737 ras responsive element binding protein 1 isoform 1 [... 71 3e-12
gi|86991432 GLI-Kruppel family member GLI2 [Homo sapiens] 70 6e-12
gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens] 70 6e-12
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 69 8e-12
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 69 8e-12
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 65 1e-10
gi|55956899 keratin 9 [Homo sapiens] 65 2e-10
gi|109255251 loricrin [Homo sapiens] 65 2e-10
gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens] 64 3e-10
gi|39812501 Sp8 transcription factor isoform 2 [Homo sapiens] 64 3e-10
gi|110431364 GLIS family zinc finger 2 [Homo sapiens] 64 3e-10
gi|170650685 zinc finger and BTB domain containing 37 isoform a ... 62 1e-09
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 62 2e-09
gi|27894378 chloride intracellular channel 6 [Homo sapiens] 61 3e-09
gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein ... 60 5e-09
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens] 60 5e-09
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] 59 8e-09
gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 59 8e-09
gi|22547201 zinc finger protein of the cerebellum 4 [Homo sapiens] 59 8e-09
gi|167466187 integrin-binding sialoprotein precursor [Homo sapiens] 59 1e-08
>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
Length = 517
Score = 1040 bits (2688), Expect = 0.0
Identities = 517/517 (100%), Positives = 517/517 (100%)
Query: 1 MAAAITDMADLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLN 60
MAAAITDMADLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLN
Sbjct: 1 MAAAITDMADLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLN 60
Query: 61 GGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEES 120
GGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEES
Sbjct: 61 GGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEES 120
Query: 121 SAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSV 180
SAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSV
Sbjct: 121 SAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSV 180
Query: 181 VSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGR 240
VSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGR
Sbjct: 181 VSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGR 240
Query: 241 STPAMMNGQGSTTSSSKNIAYNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWK 300
STPAMMNGQGSTTSSSKNIAYNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWK
Sbjct: 241 STPAMMNGQGSTTSSSKNIAYNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWK 300
Query: 301 GCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSK 360
GCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSK
Sbjct: 301 GCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSK 360
Query: 361 VSSQPKAKEESPSKAGMNKRRKLKNKRRRSLPRPHDFFDAQTLDAIRHRAICFNLSAHIE 420
VSSQPKAKEESPSKAGMNKRRKLKNKRRRSLPRPHDFFDAQTLDAIRHRAICFNLSAHIE
Sbjct: 361 VSSQPKAKEESPSKAGMNKRRKLKNKRRRSLPRPHDFFDAQTLDAIRHRAICFNLSAHIE 420
Query: 421 SLGKGHSVVFHSTVIAKRKEDSGKIKLLLHWMPEDILPDVWVNESERHQLKTKVVHLSKL 480
SLGKGHSVVFHSTVIAKRKEDSGKIKLLLHWMPEDILPDVWVNESERHQLKTKVVHLSKL
Sbjct: 421 SLGKGHSVVFHSTVIAKRKEDSGKIKLLLHWMPEDILPDVWVNESERHQLKTKVVHLSKL 480
Query: 481 PKDTALLLDPNIYRTMPQKRLKRTLIRKVFNLYLSKQ 517
PKDTALLLDPNIYRTMPQKRLKRTLIRKVFNLYLSKQ
Sbjct: 481 PKDTALLLDPNIYRTMPQKRLKRTLIRKVFNLYLSKQ 517
>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
Length = 503
Score = 1013 bits (2620), Expect = 0.0
Identities = 503/503 (100%), Positives = 503/503 (100%)
Query: 1 MAAAITDMADLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLN 60
MAAAITDMADLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLN
Sbjct: 1 MAAAITDMADLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLN 60
Query: 61 GGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEES 120
GGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEES
Sbjct: 61 GGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEES 120
Query: 121 SAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSV 180
SAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSV
Sbjct: 121 SAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSV 180
Query: 181 VSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGR 240
VSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGR
Sbjct: 181 VSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGR 240
Query: 241 STPAMMNGQGSTTSSSKNIAYNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWK 300
STPAMMNGQGSTTSSSKNIAYNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWK
Sbjct: 241 STPAMMNGQGSTTSSSKNIAYNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWK 300
Query: 301 GCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSK 360
GCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSK
Sbjct: 301 GCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSK 360
Query: 361 VSSQPKAKEESPSKAGMNKRRKLKNKRRRSLPRPHDFFDAQTLDAIRHRAICFNLSAHIE 420
VSSQPKAKEESPSKAGMNKRRKLKNKRRRSLPRPHDFFDAQTLDAIRHRAICFNLSAHIE
Sbjct: 361 VSSQPKAKEESPSKAGMNKRRKLKNKRRRSLPRPHDFFDAQTLDAIRHRAICFNLSAHIE 420
Query: 421 SLGKGHSVVFHSTVIAKRKEDSGKIKLLLHWMPEDILPDVWVNESERHQLKTKVVHLSKL 480
SLGKGHSVVFHSTVIAKRKEDSGKIKLLLHWMPEDILPDVWVNESERHQLKTKVVHLSKL
Sbjct: 421 SLGKGHSVVFHSTVIAKRKEDSGKIKLLLHWMPEDILPDVWVNESERHQLKTKVVHLSKL 480
Query: 481 PKDTALLLDPNIYRTMPQKRLKR 503
PKDTALLLDPNIYRTMPQKRLKR
Sbjct: 481 PKDTALLLDPNIYRTMPQKRLKR 503
>gi|4885279 GLI family zinc finger 1 isoform 1 [Homo sapiens]
Length = 1106
Score = 80.9 bits (198), Expect = 3e-15
Identities = 86/331 (25%), Positives = 129/331 (38%), Gaps = 39/331 (11%)
Query: 137 TRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGS 196
+R SPG + G L P +Q G S S V G GG
Sbjct: 112 SRCTSPGGSYGHLSIGTMSPSLGFP-----AQMNHQKGPSPSFGVQPCGPHDSARGGMIP 166
Query: 197 SATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTP--AMMNGQGSTTS 254
S G + ++ S+ + L E+ + D+ S S+G P M++G+
Sbjct: 167 HPQSRGPFPTCQLKSELDMLVGKCREEPLEG---DMSSPNSTGIQDPLLGMLDGREDLER 223
Query: 255 SSKN-----IAYNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPS 309
K +C WD C F+S L HI S H+ G+R FVC W GC P
Sbjct: 224 EEKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKE-FVCHWGGCSRELRPF 282
Query: 310 TSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSKVSSQPKAKE 369
+Q L HM H+G+KP KC GC S++ L H+ +H ++ +
Sbjct: 283 KAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEK-------PYMCEH 335
Query: 370 ESPSKAGMNKRRKLKNKRR-RSLPRPH---------DFFDAQTLDAIRHRAICFNLSAHI 419
E SKA N + K++ R S +P+ + D +L +H AH+
Sbjct: 336 EGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLR--KHVKTVHGPDAHV 393
Query: 420 ESLGKGHSVVFH----STVIAKRKEDSGKIK 446
+G + STV KR+ + G I+
Sbjct: 394 TKRHRGDGPLPRAPSISTVEPKREREGGPIR 424
>gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens]
Length = 978
Score = 80.1 bits (196), Expect = 4e-15
Identities = 78/294 (26%), Positives = 118/294 (40%), Gaps = 34/294 (11%)
Query: 174 GSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVD 233
G S S V G GG S G + ++ S+ + L E+ + D+
Sbjct: 16 GPSPSFGVQPCGPHDSARGGMIPHPQSRGPFPTCQLKSELDMLVGKCREEPLEG---DMS 72
Query: 234 STISSGRSTP--AMMNGQGSTTSSSKN-----IAYNCCWDQCQACFNSSPDLADHIRSIH 286
S S+G P M++G+ K +C WD C F+S L HI S H
Sbjct: 73 SPNSTGIQDPLLGMLDGREDLEREEKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEH 132
Query: 287 VDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLA 346
+ G+R FVC W GC P +Q L HM H+G+KP KC GC S++ L
Sbjct: 133 IHGERKE-FVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLK 191
Query: 347 RHVPTHFSQQNSSKVSSQPKAKEESPSKAGMNKRRKLKNKRR-RSLPRPH---------D 396
H+ +H ++ + E SKA N + K++ R S +P+
Sbjct: 192 THLRSHTGEK-------PYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKR 244
Query: 397 FFDAQTLDAIRHRAICFNLSAHIESLGKGHSVVFH----STVIAKRKEDSGKIK 446
+ D +L +H AH+ +G + STV KR+ + G I+
Sbjct: 245 YTDPSSLR--KHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKREREGGPIR 296
>gi|109637784 GLIS family zinc finger 3 isoform a [Homo sapiens]
Length = 930
Score = 75.9 bits (185), Expect = 8e-14
Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Query: 262 NCC-WDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHML 320
+CC W C A ++ +L HI +H+D ++G F C W GC P ++ L HM
Sbjct: 500 HCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMR 559
Query: 321 THSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQ 356
HSG+KP KC GC +F+ L H+ +H ++
Sbjct: 560 VHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEK 595
>gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens]
Length = 775
Score = 75.9 bits (185), Expect = 8e-14
Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Query: 262 NCC-WDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHML 320
+CC W C A ++ +L HI +H+D ++G F C W GC P ++ L HM
Sbjct: 345 HCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMR 404
Query: 321 THSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQ 356
HSG+KP KC GC +F+ L H+ +H ++
Sbjct: 405 VHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEK 440
>gi|166706915 GLIS family zinc finger 1 [Homo sapiens]
Length = 620
Score = 72.8 bits (177), Expect = 7e-13
Identities = 32/94 (34%), Positives = 48/94 (51%)
Query: 263 CCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTH 322
C W C A + +L HI H+D ++G F C W GC P ++ L HM H
Sbjct: 197 CRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVH 256
Query: 323 SGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQ 356
SG+KP KC+ GC+ +F+ L H+ +H ++
Sbjct: 257 SGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEK 290
Score = 47.4 bits (111), Expect = 3e-05
Identities = 29/110 (26%), Positives = 54/110 (49%), Gaps = 9/110 (8%)
Query: 263 CCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTH 322
C ++ C F+ +L H+RS H G++ ++C GC+ + S+ ++ +H TH
Sbjct: 264 CMFEGCSKAFSRLENLKIHLRS-HT-GEKP--YLCQHPGCQKAFSNSSDRA---KHQRTH 316
Query: 323 SGDKPFKCVVGGCNASFASQGGLARHVPTHFS--QQNSSKVSSQPKAKEE 370
KP+ C + GC+ + L +HV H + QQ K+ + P + +
Sbjct: 317 LDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHAGPDTEAD 366
>gi|22748877 basic helix-loop-helix domain containing, class B, 5
[Homo sapiens]
Length = 381
Score = 72.0 bits (175), Expect = 1e-12
Identities = 67/207 (32%), Positives = 83/207 (40%), Gaps = 32/207 (15%)
Query: 21 PPGSPGSAARGRAEPPEEEEEEEEEE-----EEAEAEAVAALLL-----NGGSGGGGGGG 70
PPG S A PP E E A+ E LL GGS G GGGG
Sbjct: 39 PPGMDLSLA----PPPRERPASSSSSPLGCFEPADPEGAGLLLPPPGGGGGGSAGSGGGG 94
Query: 71 GGGVGG-----GEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAES- 124
GGGVG G A +PS S AG + + + S GGE+ +S
Sbjct: 95 GGGVGVPGLLVGSAGVGGDPSLSSLP-AGAALCLKYGESASRGSVAESSGGEQSPDDDSD 153
Query: 125 ----LVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKG---PRGSQGGGGGGSSS 177
LV +G + SPGA + +G G P G GGGGGG SS
Sbjct: 154 GRCELVLRAGVADP----RASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSS 209
Query: 178 SSVVSSGGDEGYGTGGGGSSATSGGRR 204
S GG G G+GG SS++S ++
Sbjct: 210 SGSSGGGGGSGSGSGGSSSSSSSSSKK 236
Score = 32.7 bits (73), Expect = 0.82
Identities = 19/41 (46%), Positives = 22/41 (53%), Gaps = 7/41 (17%)
Query: 59 LNGGSGGG------GGGGGGGVG-GGEAETMSEPSPESASQ 92
L GG GGG GGGGG G G GG + + S S +S Q
Sbjct: 200 LGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQ 240
Score = 32.3 bits (72), Expect = 1.1
Identities = 15/41 (36%), Positives = 22/41 (53%)
Query: 61 GGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEE 101
GG GGGG G GGG + + S S S+S + + E++
Sbjct: 201 GGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQK 241
Score = 32.0 bits (71), Expect = 1.4
Identities = 31/127 (24%), Positives = 45/127 (35%), Gaps = 31/127 (24%)
Query: 17 LSPLPPGSP------GSAARGRAEPPEEEEEEEEEEEEAEAE-----AVAALLLNGGSGG 65
LS LP G+ SA+RG E+ +++ + E VA + G+GG
Sbjct: 116 LSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGG 175
Query: 66 GG--------------------GGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEE 105
GG GG GGG GGG + S S S +G +
Sbjct: 176 GGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSK 235
Query: 106 EEDESSS 112
+ E +
Sbjct: 236 KSKEQKA 242
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 71.6 bits (174), Expect = 2e-12
Identities = 61/166 (36%), Positives = 66/166 (39%), Gaps = 27/166 (16%)
Query: 48 EAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEE 107
E E + +LL GS GGGG GGG GGG S G
Sbjct: 443 ENEIQTYRSLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGG------------- 489
Query: 108 DESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGS 167
SSGGG GSSGG SS G SSS G G G G G
Sbjct: 490 GHGGSSGGGYGG-------GSSGGGSSGG----GYGGGSSSGGHGGSSSG-GYGGGSSGG 537
Query: 168 QGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDG 213
GGG GG SS SSGG G G+ GG ++S G G E SS G
Sbjct: 538 GGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVG--ESSSKG 581
Score = 52.4 bits (124), Expect = 1e-06
Identities = 49/165 (29%), Positives = 59/165 (35%), Gaps = 19/165 (11%)
Query: 63 SGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSA 122
S GGGGGGGG GGG + S S G SSGG S +
Sbjct: 14 SRSGGGGGGGGCGGGGGVSSLRISSSKGSLGG---------------GFSSGGFSGGSFS 58
Query: 123 ESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVS 182
GSSGG + G G G G G G GGG S
Sbjct: 59 R---GSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGG 115
Query: 183 SGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISS 227
S G G+G GGG GG G + S E ++ + D ++S
Sbjct: 116 SFGGGGFG-GGGFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLAS 159
Score = 38.1 bits (87), Expect = 0.019
Identities = 33/96 (34%), Positives = 37/96 (38%), Gaps = 9/96 (9%)
Query: 110 SSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQG 169
SS SGGG G GG SS L ++ S G G G RGS G
Sbjct: 13 SSRSGGGGGGGGC----GGGGGVSS-----LRISSSKGSLGGGFSSGGFSGGSFSRGSSG 63
Query: 170 GGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRG 205
GG G SS GG G G S++ GG G
Sbjct: 64 GGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYG 99
Score = 34.7 bits (78), Expect = 0.22
Identities = 27/68 (39%), Positives = 29/68 (42%), Gaps = 11/68 (16%)
Query: 139 SLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSA 198
S S +SS SG G G G GGGGG SS + SS G G G GG S
Sbjct: 6 SSSKHYSSSRSGGGGGGGGC-----------GGGGGVSSLRISSSKGSLGGGFSSGGFSG 54
Query: 199 TSGGRRGS 206
S R S
Sbjct: 55 GSFSRGSS 62
Score = 33.5 bits (75), Expect = 0.48
Identities = 14/17 (82%), Positives = 14/17 (82%)
Query: 61 GGSGGGGGGGGGGVGGG 77
GGS GGGG GGGG GGG
Sbjct: 114 GGSFGGGGFGGGGFGGG 130
Score = 32.3 bits (72), Expect = 1.1
Identities = 19/47 (40%), Positives = 23/47 (48%)
Query: 61 GGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEE 107
GG GGG GG GG + G E TM + AS + EE + E E
Sbjct: 129 GGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELE 175
Score = 32.0 bits (71), Expect = 1.4
Identities = 33/89 (37%), Positives = 36/89 (40%), Gaps = 7/89 (7%)
Query: 132 SSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGG---GG--GSSSSSVVSSGGD 186
SS + S S G G G +GS GGG GG G S S S GG
Sbjct: 7 SSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGC 66
Query: 187 EGYGTGG-GGSSATSGGR-RGSLEMSSDG 213
G +GG GG GG RGS SS G
Sbjct: 67 FGGSSGGYGGLGGFGGGSFRGSYGSSSFG 95
Score = 32.0 bits (71), Expect = 1.4
Identities = 13/17 (76%), Positives = 13/17 (76%)
Query: 61 GGSGGGGGGGGGGVGGG 77
GG G GGGG GGG GGG
Sbjct: 118 GGGGFGGGGFGGGFGGG 134
Score = 31.2 bits (69), Expect = 2.4
Identities = 13/17 (76%), Positives = 13/17 (76%)
Query: 61 GGSGGGGGGGGGGVGGG 77
GGS GGG GGGG GGG
Sbjct: 109 GGSFGGGSFGGGGFGGG 125
>gi|51173735 ras responsive element binding protein 1 isoform 2
[Homo sapiens]
Length = 1687
Score = 70.9 bits (172), Expect = 3e-12
Identities = 53/184 (28%), Positives = 83/184 (45%), Gaps = 30/184 (16%)
Query: 217 SRMDSEDSISSTIMDVDSTISSGRSTPAMMN----------GQGSTTSSSKNIAYNCCWD 266
S + S +++ S +M V +G S + + G+ + + + +YNC
Sbjct: 12 SDLSSINTMMSAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNC--P 69
Query: 267 QCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGDK 326
C+ + L HIR + D GG C + +S S L RHML HSG++
Sbjct: 70 LCEKICTTQHQLTMHIRQHNTD--TGGAD----HSCSICGKSLSSASSLDRHMLVHSGER 123
Query: 327 PFKCVVGGCNASFASQGGLARHVPTHFSQQNSSKVSSQPKAKEESPSKAGMNKRRKLKNK 386
P+KC V C SF + G + RH+ H NS+ ++ P SP KRR+L +K
Sbjct: 124 PYKCTV--CGQSFTTNGNMHRHMKIHEKDPNSATATAPP-----SPL-----KRRRLSSK 171
Query: 387 RRRS 390
R+ S
Sbjct: 172 RKLS 175
Score = 47.4 bits (111), Expect = 3e-05
Identities = 73/319 (22%), Positives = 110/319 (34%), Gaps = 38/319 (11%)
Query: 78 EAETMSEPSPESASQAGEDEDEEEDDE------EEEDESSSSGGGEEESSAESLVGSSGG 131
+ E SE + E AG+ E+ E EE S EEE E G + G
Sbjct: 1291 DREQPSEGATELRQVAGDAPVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADG 1350
Query: 132 SSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSS---VVSSGGDEG 188
+ D A+S+ S D D L + K G G GG++S + G
Sbjct: 1351 AEED--------ASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSF 1402
Query: 189 YGTGGGGSSATSGGRRGSLEMSSDGE------PLSRMDSEDSISSTIMDVDSTISSGRST 242
G + GR+ + DG P + E+ T +V +
Sbjct: 1403 KFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEA 1462
Query: 243 PAMMNGQGSTTSSSKNIAYNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVC--LWK 300
PA + + S D A S + +D + D + K
Sbjct: 1463 PAEKLAEETEGPS----------DGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKK 1512
Query: 301 GCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSK 360
C V N S L RHM +H+G++P+KC C +F + L RH H + +K
Sbjct: 1513 VCSVCNKRFWSLQDLTRHMRSHTGERPYKCQT--CERTFTLKHSLVRHQRIH-QKARHAK 1569
Query: 361 VSSQPKAKEESPSKAGMNK 379
+ KEE + N+
Sbjct: 1570 HHGKDSDKEERGEEDSENE 1588
Score = 39.3 bits (90), Expect = 0.009
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 28/147 (19%)
Query: 207 LEMSSDGEPLSRMDSEDSISSTIMDVD----STISSGRSTPAMMNGQGSTTSSSKNIAYN 262
LE S E L + E I I + + T G+ TPAM + + Y
Sbjct: 596 LEQDSIIEALLPLSMEAKIKQEITEGELKAFMTAPGGKKTPAM-----------RKVLYP 644
Query: 263 CCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTH 322
C + C F S L H+RS H+ + ++ C + + + ++ L RH+ TH
Sbjct: 645 CRF--CNQVFAFSGVLRAHVRS-HLG-------ISPYQ-CNICDYIAADKAALIRHLRTH 693
Query: 323 SGDKPFKCVVGGCNASFASQGGLARHV 349
SG++P+ C + C+ F + RH+
Sbjct: 694 SGERPYICKI--CHYPFTVKANCERHL 718
Score = 34.7 bits (78), Expect = 0.22
Identities = 43/180 (23%), Positives = 58/180 (32%), Gaps = 54/180 (30%)
Query: 30 RGRAEPPEEE-------------EEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGG 76
RG + PEEE EE+ + + + L+ + G G G GG
Sbjct: 1329 RGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAAS 1388
Query: 77 GE-----------------------AETMSEPSPESASQAGEDEDEEEDDEEEEDE---- 109
E A EP E A E+ + E+E++
Sbjct: 1389 QEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPET 1448
Query: 110 -----SSSSGGGE--EESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPK 162
S+ G GE E AE G S G S+ E R SS D D K + PK
Sbjct: 1449 PAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKR-------SSEKSDDDKKPKTDSPK 1501
Score = 34.3 bits (77), Expect = 0.28
Identities = 18/59 (30%), Positives = 29/59 (49%)
Query: 90 ASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSS 148
A G+D D+EE EE+ + S+ G S E+ + + + TRS G AS++
Sbjct: 1568 AKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEGLASAT 1626
>gi|51173737 ras responsive element binding protein 1 isoform 1
[Homo sapiens]
Length = 1742
Score = 70.9 bits (172), Expect = 3e-12
Identities = 53/184 (28%), Positives = 83/184 (45%), Gaps = 30/184 (16%)
Query: 217 SRMDSEDSISSTIMDVDSTISSGRSTPAMMN----------GQGSTTSSSKNIAYNCCWD 266
S + S +++ S +M V +G S + + G+ + + + +YNC
Sbjct: 12 SDLSSINTMMSAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNC--P 69
Query: 267 QCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGDK 326
C+ + L HIR + D GG C + +S S L RHML HSG++
Sbjct: 70 LCEKICTTQHQLTMHIRQHNTD--TGGAD----HSCSICGKSLSSASSLDRHMLVHSGER 123
Query: 327 PFKCVVGGCNASFASQGGLARHVPTHFSQQNSSKVSSQPKAKEESPSKAGMNKRRKLKNK 386
P+KC V C SF + G + RH+ H NS+ ++ P SP KRR+L +K
Sbjct: 124 PYKCTV--CGQSFTTNGNMHRHMKIHEKDPNSATATAPP-----SPL-----KRRRLSSK 171
Query: 387 RRRS 390
R+ S
Sbjct: 172 RKLS 175
Score = 47.4 bits (111), Expect = 3e-05
Identities = 73/319 (22%), Positives = 110/319 (34%), Gaps = 38/319 (11%)
Query: 78 EAETMSEPSPESASQAGEDEDEEEDDE------EEEDESSSSGGGEEESSAESLVGSSGG 131
+ E SE + E AG+ E+ E EE S EEE E G + G
Sbjct: 1346 DREQPSEGATELRQVAGDAPVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADG 1405
Query: 132 SSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSS---VVSSGGDEG 188
+ D A+S+ S D D L + K G G GG++S + G
Sbjct: 1406 AEED--------ASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSF 1457
Query: 189 YGTGGGGSSATSGGRRGSLEMSSDGE------PLSRMDSEDSISSTIMDVDSTISSGRST 242
G + GR+ + DG P + E+ T +V +
Sbjct: 1458 KFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEA 1517
Query: 243 PAMMNGQGSTTSSSKNIAYNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVC--LWK 300
PA + + S D A S + +D + D + K
Sbjct: 1518 PAEKLAEETEGPS----------DGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKK 1567
Query: 301 GCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSK 360
C V N S L RHM +H+G++P+KC C +F + L RH H + +K
Sbjct: 1568 VCSVCNKRFWSLQDLTRHMRSHTGERPYKCQT--CERTFTLKHSLVRHQRIH-QKARHAK 1624
Query: 361 VSSQPKAKEESPSKAGMNK 379
+ KEE + N+
Sbjct: 1625 HHGKDSDKEERGEEDSENE 1643
Score = 40.4 bits (93), Expect = 0.004
Identities = 19/36 (52%), Positives = 24/36 (66%), Gaps = 2/36 (5%)
Query: 313 SWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARH 348
S LQRHMLTH+G KPF C C+A F+++ RH
Sbjct: 1259 SSLQRHMLTHTGQKPFPC--QKCDAFFSTKSNCERH 1292
Score = 39.3 bits (90), Expect = 0.009
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 28/147 (19%)
Query: 207 LEMSSDGEPLSRMDSEDSISSTIMDVD----STISSGRSTPAMMNGQGSTTSSSKNIAYN 262
LE S E L + E I I + + T G+ TPAM + + Y
Sbjct: 596 LEQDSIIEALLPLSMEAKIKQEITEGELKAFMTAPGGKKTPAM-----------RKVLYP 644
Query: 263 CCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTH 322
C + C F S L H+RS H+ + ++ C + + + ++ L RH+ TH
Sbjct: 645 CRF--CNQVFAFSGVLRAHVRS-HLG-------ISPYQ-CNICDYIAADKAALIRHLRTH 693
Query: 323 SGDKPFKCVVGGCNASFASQGGLARHV 349
SG++P+ C + C+ F + RH+
Sbjct: 694 SGERPYICKI--CHYPFTVKANCERHL 718
Score = 34.7 bits (78), Expect = 0.22
Identities = 43/180 (23%), Positives = 58/180 (32%), Gaps = 54/180 (30%)
Query: 30 RGRAEPPEEE-------------EEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGG 76
RG + PEEE EE+ + + + L+ + G G G GG
Sbjct: 1384 RGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAAS 1443
Query: 77 GE-----------------------AETMSEPSPESASQAGEDEDEEEDDEEEEDE---- 109
E A EP E A E+ + E+E++
Sbjct: 1444 QEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPET 1503
Query: 110 -----SSSSGGGE--EESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPK 162
S+ G GE E AE G S G S+ E R SS D D K + PK
Sbjct: 1504 PAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKR-------SSEKSDDDKKPKTDSPK 1556
Score = 34.3 bits (77), Expect = 0.28
Identities = 18/59 (30%), Positives = 29/59 (49%)
Query: 90 ASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSS 148
A G+D D+EE EE+ + S+ G S E+ + + + TRS G AS++
Sbjct: 1623 AKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEGLASAT 1681
>gi|86991432 GLI-Kruppel family member GLI2 [Homo sapiens]
Length = 1586
Score = 69.7 bits (169), Expect = 6e-12
Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Query: 262 NCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLT 321
NC W+ C +++ L HI + H+ G++ FVC W+ C P +Q L HM
Sbjct: 438 NCHWEDCTKEYDTQEQLVHHINNEHIHGEKKE-FVCRWQACTREQKPFKAQYMLVVHMRR 496
Query: 322 HSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQ 356
H+G+KP KC GC+ +++ L H+ +H ++
Sbjct: 497 HTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEK 531
Score = 49.3 bits (116), Expect = 8e-06
Identities = 35/124 (28%), Positives = 59/124 (47%), Gaps = 15/124 (12%)
Query: 261 YNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGC-KVYNTPSTSQSWLQRHM 319
+ C ++ C ++ +L H+RS H G++ +VC +GC K ++ S R
Sbjct: 503 HKCTFEGCSKAYSRLENLKTHLRS-HT-GEKP--YVCEHEGCNKAFSNASDRAKHQNR-- 556
Query: 320 LTHSGDKPFKCVVGGCNASFASQGGLARHVPT------HFSQQNSSKVSSQ-PKAKEESP 372
THS +KP+ C + GC + L +HV T H +++ + V + P KE
Sbjct: 557 -THSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGD 615
Query: 373 SKAG 376
S+AG
Sbjct: 616 SEAG 619
>gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens]
Length = 1580
Score = 69.7 bits (169), Expect = 6e-12
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 8/169 (4%)
Query: 194 GGSSATSGGRRGSLEMSSDGEPL----SRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQ 249
G S ++ +SS G+P+ S++ ++ + S G +T G
Sbjct: 408 GPSESSQNKPTSESAVSSTGDPMHNKRSKIKPDEDLPSPGARGQQEQPEG-TTLVKEEGD 466
Query: 250 GSTTSSSKNIAY--NCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNT 307
+ + Y NC W+ C F++ L HI + H+ G++ FVC W C
Sbjct: 467 KDESKQEPEVIYETNCHWEGCAREFDTQEQLVHHINNDHIHGEKKE-FVCRWLDCSREQK 525
Query: 308 PSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQ 356
P +Q L HM H+G+KP KC GC +++ L H+ +H ++
Sbjct: 526 PFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEK 574
Score = 47.4 bits (111), Expect = 3e-05
Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 14/120 (11%)
Query: 261 YNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGC-KVYNTPSTSQSWLQRHM 319
+ C ++ C ++ +L H+RS H G++ +VC +GC K ++ S R
Sbjct: 546 HKCTFEGCTKAYSRLENLKTHLRS-HT-GEKP--YVCEHEGCNKAFSNASDRAKHQNR-- 599
Query: 320 LTHSGDKPFKCVVGGCNASFASQGGLARHVPT------HFSQQNSSKVSSQPKAKEESPS 373
THS +KP+ C + GC + L +HV T H +++ + +P +S S
Sbjct: 600 -THSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGS 658
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 69.3 bits (168), Expect = 8e-12
Identities = 58/189 (30%), Positives = 69/189 (36%), Gaps = 18/189 (9%)
Query: 26 GSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSEP 85
G G E E E + EEE EE E E G G G G G G GE E E
Sbjct: 842 GEEEEGEGEEEEGEGKGEEEGEEGEGEE------EGEEGEGEGEEEEGEGEGEEEGEGEG 895
Query: 86 SPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAA 145
E GE+E E E +EEE + G E E E G G + G
Sbjct: 896 EEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEW 955
Query: 146 SSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRG 205
+G+G EG EE +G G +G G G +EG G G G G
Sbjct: 956 EGEEEEGEG-EGEEEGEG-EGEEGEGEGEE----------EEGEGEGEEEEGEEEGEEEG 1003
Query: 206 SLEMSSDGE 214
E +GE
Sbjct: 1004 EGEEEGEGE 1012
Score = 68.2 bits (165), Expect = 2e-11
Identities = 62/201 (30%), Positives = 74/201 (36%), Gaps = 19/201 (9%)
Query: 26 GSAARGRAEPPEEEE---EEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETM 82
G G E EE E EEEE E E E E G G G G G G GE
Sbjct: 878 GEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGE---- 933
Query: 83 SEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSP 142
E E + GE E EEE+ E E +E G GEEE E G G +
Sbjct: 934 -EEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEE------- 985
Query: 143 GAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGG 202
G +G+ +EG EE +G +G G G+EG G G G
Sbjct: 986 GEGEGEEEEGE-EEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGE 1044
Query: 203 RRGSLEMSSDGEPLSRMDSED 223
R E +GE R E+
Sbjct: 1045 ER---EKEGEGEENRRNREEE 1062
Score = 63.5 bits (153), Expect = 4e-10
Identities = 49/145 (33%), Positives = 58/145 (40%), Gaps = 23/145 (15%)
Query: 26 GSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSEP 85
G G E EEE E E EEEE E E G G G G G G GE E
Sbjct: 939 GEGEDGEGEGEEEEGEWEGEEEEGEGE---------GEEEGEGEGEEGEGEGEEE----- 984
Query: 86 SPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAE---SLVGSSGGSSSDETRSLSP 142
E + E+E EEE +EE E E G GEEE E + G G +E
Sbjct: 985 --EGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEE 1042
Query: 143 GAASSSSGDGD----GKEGLEEPKG 163
G G+G+ +E EE +G
Sbjct: 1043 GEEREKEGEGEENRRNREEEEEEEG 1067
Score = 62.8 bits (151), Expect = 7e-10
Identities = 59/195 (30%), Positives = 72/195 (36%), Gaps = 19/195 (9%)
Query: 30 RGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSEPSPES 89
R E EEE ++ E EE E E GG GG G GE E E E
Sbjct: 780 RAGKEEKGEEEGDQGEGEEEETEGRGE---EKEEGGEVEGGEVEEGKGEREE-EEEEGEG 835
Query: 90 ASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSS 149
+ GE E+EE + EEEE E GEE E G G +E G
Sbjct: 836 EEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEE--GEEGEGEGEEEEGEGEG---EEE 890
Query: 150 GDGDGK------EGLEEPKGPRGSQGGGGGGSSSSSVVSSGGD----EGYGTGGGGSSAT 199
G+G+G+ EG EE +G + G G G G+ EG G G G
Sbjct: 891 GEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEE 950
Query: 200 SGGRRGSLEMSSDGE 214
G E +GE
Sbjct: 951 EEGEWEGEEEEGEGE 965
Score = 60.5 bits (145), Expect = 4e-09
Identities = 54/182 (29%), Positives = 67/182 (36%), Gaps = 9/182 (4%)
Query: 34 EPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSEPSPESASQA 93
E E E E E+EE E + E A G G G G G E E +
Sbjct: 760 EGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEV 819
Query: 94 GEDEDEEEDDEEE-EDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDG 152
E + E E++EEE E E G EEE E G G E G G+G
Sbjct: 820 EEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEE---GEGEEEGEEGEG 876
Query: 153 DGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSSD 212
+G+E EE +G +G G G G +EG G G G G E +
Sbjct: 877 EGEE--EEGEGEGEEEGEGEGEEEEGE--GEGEEEGEGEGEEEEGEGKGEEEGE-EGEGE 931
Query: 213 GE 214
GE
Sbjct: 932 GE 933
Score = 58.9 bits (141), Expect = 1e-08
Identities = 51/183 (27%), Positives = 66/183 (36%), Gaps = 17/183 (9%)
Query: 37 EEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGED 96
EEEE + EEEEE E E G G G V G + E E + E
Sbjct: 739 EEEEGDREEEEEKEGE------------GKEEGEGEEVEGEREKEEGERKKEERAGKEEK 786
Query: 97 EDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKE 156
+EE D E E+E + G E+E E G + G G+G+ +E
Sbjct: 787 GEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEE 846
Query: 157 G---LEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGG--RRGSLEMSS 211
G EE +G +G G G G+E G G G G G E
Sbjct: 847 GEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEE 906
Query: 212 DGE 214
+GE
Sbjct: 907 EGE 909
Score = 55.8 bits (133), Expect = 9e-08
Identities = 50/196 (25%), Positives = 68/196 (34%), Gaps = 31/196 (15%)
Query: 25 PGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSE 84
PG + AE E ++ + EE+E+ E E G + E E
Sbjct: 689 PGEGEKELAEKEEWKKRDGEEQEQKEREQ----------------------GHQKERNQE 726
Query: 85 PSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGA 144
+ GE E+EE D EEEE++ G G+EE E + G + + G
Sbjct: 727 MEEGGEEEHGEGEEEEGDREEEEEKE---GEGKEEGEGEEVEGEREKEEGERKKEERAGK 783
Query: 145 ASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGG------DEGYGTGGGGSSA 198
+GD EG EE RG + GG V G +EG G G
Sbjct: 784 EEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGE 843
Query: 199 TSGGRRGSLEMSSDGE 214
G E GE
Sbjct: 844 EEEGEGEEEEGEGKGE 859
Score = 51.6 bits (122), Expect = 2e-06
Identities = 47/166 (28%), Positives = 56/166 (33%), Gaps = 16/166 (9%)
Query: 23 GSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETM 82
G G E E E EEE E E E E G G G G G G GE
Sbjct: 887 GEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEG 946
Query: 83 SEPSPESASQAGEDEDEEEDDEEEEDESSSSGG---------------GEEESSAESLVG 127
E + E+E E E +EE E E G GEEE E
Sbjct: 947 EGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGE 1006
Query: 128 SSG-GSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGG 172
G G +E G G+G+G+E E +G + G G
Sbjct: 1007 EEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEG 1052
Score = 49.3 bits (116), Expect = 8e-06
Identities = 49/164 (29%), Positives = 58/164 (35%), Gaps = 16/164 (9%)
Query: 26 GSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGG---GGGGGVGGGEAETM 82
G G E EEE E E EEEE E E G G G G G G E E
Sbjct: 972 GEGEEGEGEGEEEEGEGEGEEEEGEEE---------GEEEGEGEEEGEGEGEEEEEGEVE 1022
Query: 83 SEPSPESASQAGEDEDEEEDDEEEEDE---SSSSGGGEEESSAESLVGSSGGSSSDETRS 139
E E GE+E+ EE+ EE E E + EEE E +G ++
Sbjct: 1023 GEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDG 1082
Query: 140 LSPGAASSSSGDGD-GKEGLEEPKGPRGSQGGGGGGSSSSSVVS 182
S G GK + K +QG G S V S
Sbjct: 1083 EEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQS 1126
Score = 32.7 bits (73), Expect = 0.82
Identities = 37/131 (28%), Positives = 50/131 (38%), Gaps = 12/131 (9%)
Query: 87 PESASQAGEDEDEEEDDEEEEDESSSSGGGEEE--SSAESLVGSSGGSSSDETRSLSPGA 144
P + +A DE+ E +E+E E S G EE+ + E V GG ++T LS
Sbjct: 572 PATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGG-RKEKTEILSDDL 630
Query: 145 ASSSS-GDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGR 203
+ +G K E GP G G G SS DE G
Sbjct: 631 TDKAEVSEGKAKSVGEAEDGPEGR--GDGTCEEGSSGAEHWQDEEREKGEKDKG------ 682
Query: 204 RGSLEMSSDGE 214
RG +E +GE
Sbjct: 683 RGEMERPGEGE 693
Score = 30.8 bits (68), Expect = 3.1
Identities = 45/198 (22%), Positives = 67/198 (33%), Gaps = 43/198 (21%)
Query: 34 EPPEEEEEEEE------EEEEAEA-----------EAVAALLLNGGSGGGGGGGGGGVGG 76
E PEE+E E+ EE+E EA + +L + + G
Sbjct: 585 EIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSV 644
Query: 77 GEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDE 136
GEAE E + + G E DEE E G GE E E G + +E
Sbjct: 645 GEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGE---GEKELAEKEE 701
Query: 137 TRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGS 196
+ DG+ +E E +G + + + GG+E +G G
Sbjct: 702 WK----------KRDGEEQEQKEREQGHQ---------KERNQEMEEGGEEEHGEG---- 738
Query: 197 SATSGGRRGSLEMSSDGE 214
G R E +G+
Sbjct: 739 EEEEGDREEEEEKEGEGK 756
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 69.3 bits (168), Expect = 8e-12
Identities = 71/252 (28%), Positives = 85/252 (33%), Gaps = 35/252 (13%)
Query: 27 SAARGRAEPPEEEE-----EEEEEEEEAEAEAVAALLLNGGSGGGG----------GGGG 71
S A+G P EE E + E +A ALLL G GG G
Sbjct: 2446 SGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYP 2505
Query: 72 GGVGGGE----------AETMSEPSP-----ESASQAGEDEDEEEDDEEEEDESSSSGGG 116
G E + EP P +S + D+ + E D EE ESSSS
Sbjct: 2506 PAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSS-- 2563
Query: 117 EEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSS 176
SS S SS SS ET G + G G G S SS
Sbjct: 2564 ---SSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSS 2620
Query: 177 SSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTI 236
SSS SS + SS++S S SS S S S SST + S
Sbjct: 2621 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCS 2680
Query: 237 SSGRSTPAMMNG 248
S + PA G
Sbjct: 2681 SDDEAAPAPTAG 2692
Score = 60.5 bits (145), Expect = 4e-09
Identities = 42/170 (24%), Positives = 63/170 (37%), Gaps = 7/170 (4%)
Query: 23 GSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGS-------GGGGGGGGGGVG 75
G+P S + +AE EE E + + + ++ + GS G G GG G G
Sbjct: 2539 GNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTG 2598
Query: 76 GGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSD 135
G S + AS + SSSS SS+ S SS SSS
Sbjct: 2599 GRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2658
Query: 136 ETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGG 185
+ S S ++SSS+ D D ++ P + G + + G
Sbjct: 2659 SSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAG 2708
Score = 40.0 bits (92), Expect = 0.005
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 16/75 (21%)
Query: 78 EAETMSEPSPESASQAGEDEDEEEDDEEE--EDESSSSGGGEEESSAESLVGSSGGSSSD 135
EAE S S S +DE EE+DEEE E+E +SGGG + E
Sbjct: 1806 EAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLGARE------------ 1853
Query: 136 ETRSLSPGAASSSSG 150
R+LSPG S G
Sbjct: 1854 --RALSPGLEESGLG 1866
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 65.5 bits (158), Expect = 1e-10
Identities = 57/268 (21%), Positives = 103/268 (38%), Gaps = 10/268 (3%)
Query: 27 SAARGRAEPPEEEEEEE--------EEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGE 78
S++RG A +E ++ E++++++ + + G+G G G+
Sbjct: 485 SSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGK 544
Query: 79 AETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSS--SDE 136
++ S S S S D + D + + SSS + S++S S SS SD
Sbjct: 545 GKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDS 604
Query: 137 TRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGS 196
+ S +S SS D K + + S S+S SS + + +
Sbjct: 605 SDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSN 664
Query: 197 SATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSS 256
S+ S S + SS + + DS DS S+ S S + + + S ++SS
Sbjct: 665 SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSS 724
Query: 257 KNIAYNCCWDQCQACFNSSPDLADHIRS 284
+ + N + + S D +D S
Sbjct: 725 DSDSSNSSDSSDSSNSSDSSDSSDSSNS 752
Score = 63.5 bits (153), Expect = 4e-10
Identities = 46/182 (25%), Positives = 71/182 (39%), Gaps = 1/182 (0%)
Query: 78 EAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEE-ESSAESLVGSSGGSSSDE 136
++++ S +S+ D D + D S SS + +S ++S S S SD
Sbjct: 579 DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS 638
Query: 137 TRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGS 196
S +S SS + D + S SSSSS S+ D + S
Sbjct: 639 KSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNS 698
Query: 197 SATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSS 256
S +S S SSD S +S DS SS D + +S S+ + + S +S S
Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758
Query: 257 KN 258
+
Sbjct: 759 SD 760
Score = 63.5 bits (153), Expect = 4e-10
Identities = 53/264 (20%), Positives = 97/264 (36%), Gaps = 15/264 (5%)
Query: 6 TDMADLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAE----AEAVAALLLNG 61
+D +D S S S S + +E + + + + ++ + + + N
Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 731
Query: 62 GSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESS 121
++ S+ S S S D + D + D S+SS + +S
Sbjct: 732 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNS 791
Query: 122 AESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVV 181
++S S S+S ++ + S + SS S D D + S SS SS
Sbjct: 792 SDS----SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS 847
Query: 182 SSGGD-------EGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDS 234
S G D + + S+ S S + S E + DS DS +S+ D
Sbjct: 848 SDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD 907
Query: 235 TISSGRSTPAMMNGQGSTTSSSKN 258
+ +S S+ + + S +S+S +
Sbjct: 908 SSNSSDSSDSSNSSDSSESSNSSD 931
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/182 (26%), Positives = 70/182 (38%), Gaps = 3/182 (1%)
Query: 83 SEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSP 142
S+ S S S D + D D S+SS + S+ S S SSD S S
Sbjct: 657 SDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS 716
Query: 143 GAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGG 202
+++S+S D D + S SS+SS S D + SS +S
Sbjct: 717 DSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDS 776
Query: 203 RRGSLEMSSDGEPLSRMDSEDSISS--TIMDVDSTISSGRSTPAMMNGQGSTTSSSKNIA 260
S S + + DS DS +S + DS+ SS S N S+ SS + +
Sbjct: 777 SDSS-NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDS 835
Query: 261 YN 262
N
Sbjct: 836 SN 837
Score = 58.9 bits (141), Expect = 1e-08
Identities = 45/176 (25%), Positives = 68/176 (38%), Gaps = 8/176 (4%)
Query: 83 SEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSP 142
S+ S S S D + D + D S+SS + S++S S +SSD + S
Sbjct: 974 SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033
Query: 143 GAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGG 202
+S SS D + + S SS SS S D + SS +S
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN- 1092
Query: 203 RRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSSKN 258
S + S + DS DS S+ DS+ SS S + + ++ SS +
Sbjct: 1093 ---SSDSSDSSDSSDSSDSSDSSDSS----DSSDSSNSSDSSDSSDSSDSSDSSNS 1141
Score = 58.5 bits (140), Expect = 1e-08
Identities = 55/253 (21%), Positives = 91/253 (35%), Gaps = 8/253 (3%)
Query: 6 TDMADLEELSRLSPLPPGSPGSAA--RGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGS 63
+D +D S S S GS + R++ + + + +++ + N S
Sbjct: 830 SDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESS 889
Query: 64 GGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAE 123
++ S S S S D E + + + S SS + S++
Sbjct: 890 NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD 949
Query: 124 SLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSS 183
S S +SSD + S S + S+SS D + S SS+SS S
Sbjct: 950 SSNSSDSSNSSDSSNS-SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD 1008
Query: 184 GGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTP 243
D + SS +S S + S + DS DS S+ DS+ SS S
Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSS-DSSDSSDSSDSSDSSDSSDSS----DSSNSSDSSDS 1063
Query: 244 AMMNGQGSTTSSS 256
+ + ++ SS
Sbjct: 1064 SDSSDSSDSSDSS 1076
Score = 58.2 bits (139), Expect = 2e-08
Identities = 42/162 (25%), Positives = 62/162 (38%)
Query: 95 EDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDG 154
+D+ + DD DES+ + ES S +SDE++ G+ S + D D
Sbjct: 456 DDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDS 515
Query: 155 KEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGE 214
+ G G + S G + + SS +S S SSD
Sbjct: 516 DSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSN 575
Query: 215 PLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSS 256
S DS DS SS D DS+ SS S + + ++ SS
Sbjct: 576 SSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSS 617
Score = 58.2 bits (139), Expect = 2e-08
Identities = 52/256 (20%), Positives = 91/256 (35%), Gaps = 10/256 (3%)
Query: 6 TDMADLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGG 65
+D ++ + S S S S + ++ + E + + + + + +
Sbjct: 853 SDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912
Query: 66 GGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEED-----ESSSSGGGEEES 120
E+ S+ S S S D + D D +SS+S + +
Sbjct: 913 DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972
Query: 121 SAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSV 180
S++S S+ SSD + S +S SS D + + S SS+SS
Sbjct: 973 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032
Query: 181 VSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGR 240
S D + SS +S S + S + DS DS S+ DS+ SS
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSS-DSSDSSDSSDSSDSSDSSDSS----DSSESSDS 1087
Query: 241 STPAMMNGQGSTTSSS 256
S + + ++ SS
Sbjct: 1088 SDSSNSSDSSDSSDSS 1103
Score = 58.2 bits (139), Expect = 2e-08
Identities = 45/179 (25%), Positives = 69/179 (38%), Gaps = 8/179 (4%)
Query: 78 EAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDET 137
++ S+ S S S D + D + D S+SS + S++S S+ SSD +
Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSS 1148
Query: 138 RSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSS 197
S +S SS D + + S SS SS S D + SS
Sbjct: 1149 ESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1208
Query: 198 ATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSS 256
+S S + S + DS DS S+ DS+ SS S + + ++ SS
Sbjct: 1209 DSSD----SSDSSDSSDSSDSSDSSDSNESS----DSSDSSDSSDSSNSSDSSDSSDSS 1259
Score = 57.0 bits (136), Expect = 4e-08
Identities = 45/180 (25%), Positives = 70/180 (38%), Gaps = 6/180 (3%)
Query: 83 SEPSPESASQAGEDEDEEEDDEEEED--ESSSSGGGEEESSAESLVGSSGGSSSDETRSL 140
S S +S S + + E + D + + D +S+SS + S++S S+ SSD + S
Sbjct: 616 SSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSS 675
Query: 141 SPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATS 200
++S SS D + + S S SS S + SS +S
Sbjct: 676 DSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSS 735
Query: 201 GGRRGSLEMSSDGEPLSRMDSEDSISSTIMD----VDSTISSGRSTPAMMNGQGSTTSSS 256
S S S S+ S SS D DS+ SS S + N +++ SS
Sbjct: 736 DSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSS 795
Score = 56.6 bits (135), Expect = 5e-08
Identities = 45/257 (17%), Positives = 93/257 (36%), Gaps = 6/257 (2%)
Query: 6 TDMADLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGG 65
++ +D + S S S S + ++ + + + + + + ++ + +
Sbjct: 780 SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839
Query: 66 GGGGGGGGVGGGEAETMSEPSPESASQAGEDEDE----EEDDEEEEDESSSSGGGEEESS 121
G ++++ + ++S + + D + D + +ESS+S + S+
Sbjct: 840 DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN 899
Query: 122 AESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVV 181
+ S +SSD + S + +S SS D + S SS SS
Sbjct: 900 SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959
Query: 182 SSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRS 241
S + + S ++ SSD S DS DS +S+ S S +
Sbjct: 960 SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS--DSSDSSNSSDSSDSSDSSDSSN 1017
Query: 242 TPAMMNGQGSTTSSSKN 258
+ N S+ SS +
Sbjct: 1018 SSDSSNSSDSSNSSDSS 1034
Score = 56.6 bits (135), Expect = 5e-08
Identities = 53/261 (20%), Positives = 86/261 (32%), Gaps = 8/261 (3%)
Query: 6 TDMADLEELSRLSPL--------PPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAAL 57
+D +D E S S S S + ++ + E + + +
Sbjct: 880 SDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSS 939
Query: 58 LLNGGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGE 117
+ S + S S +S S D D + D S SS +
Sbjct: 940 NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999
Query: 118 EESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSS 177
+S++S S SS+ + S + +S+SS D + + S SS
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1059
Query: 178 SSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTIS 237
SS S D + SS +S S +S S S+ S SS D +
Sbjct: 1060 SSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1119
Query: 238 SGRSTPAMMNGQGSTTSSSKN 258
S S+ + + S +S S N
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSN 1140
Score = 56.2 bits (134), Expect = 7e-08
Identities = 53/262 (20%), Positives = 93/262 (35%), Gaps = 7/262 (2%)
Query: 25 PGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSE 84
P S+ E + +A + + G+G G ++T +
Sbjct: 465 PNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNS 524
Query: 85 PSPESASQAGEDEDEEE-----DDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRS 139
S + + +D D+ + D + D S SS + S++S S SSSD S
Sbjct: 525 DSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDS-DSSDSNSSSDSDSS 583
Query: 140 LSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSAT 199
S + SS S D + S SS S SS + S ++
Sbjct: 584 DSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSS 643
Query: 200 SGGRRGSLEMSSDGEPLSRMDSEDSI-SSTIMDVDSTISSGRSTPAMMNGQGSTTSSSKN 258
S + S + + +S DS SS D S+ S S+ + + S +S S +
Sbjct: 644 DSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSD 703
Query: 259 IAYNCCWDQCQACFNSSPDLAD 280
+ + D + +S+ + +D
Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSD 725
Score = 56.2 bits (134), Expect = 7e-08
Identities = 53/257 (20%), Positives = 87/257 (33%), Gaps = 4/257 (1%)
Query: 6 TDMADLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGG 65
+D +D + S S S S + ++ + + +++ + + S
Sbjct: 992 SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1051
Query: 66 GGGGGGGGVGGGEAETMSEPSPESA--SQAGEDED--EEEDDEEEEDESSSSGGGEEESS 121
+ S S +S+ S + E D + + + D S SS + S
Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS 1111
Query: 122 AESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVV 181
++S S +SSD + S +S SS D + E S SS SS
Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDS 1171
Query: 182 SSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRS 241
S D + SS +S S S S S+ S SS D + S S
Sbjct: 1172 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1231
Query: 242 TPAMMNGQGSTTSSSKN 258
+ + S +S S N
Sbjct: 1232 NESSDSSDSSDSSDSSN 1248
Score = 55.5 bits (132), Expect = 1e-07
Identities = 55/255 (21%), Positives = 89/255 (34%), Gaps = 7/255 (2%)
Query: 6 TDMADLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGG 65
+D +D + S S S S + ++ + + + + +E+ + + +
Sbjct: 1037 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS--DSSNSS 1094
Query: 66 GGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGG-EEES--SA 122
++ S+ S S S D + D + D S+SS ES S+
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154
Query: 123 ESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVS 182
+S S SSD + S +S+SS D + + S SS SS S
Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1214
Query: 183 SGGDEGYGTGGGGSSAT--SGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGR 240
D + SS + S S + S DS DS ST D + S +
Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274
Query: 241 STPAMMNGQGSTTSS 255
S NG S + S
Sbjct: 1275 SGNGNNNGSDSDSDS 1289
Score = 55.1 bits (131), Expect = 2e-07
Identities = 43/173 (24%), Positives = 68/173 (39%), Gaps = 6/173 (3%)
Query: 86 SPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAA 145
S +S S++ + D + D S SS S++S S SSSD + S +
Sbjct: 633 SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692
Query: 146 SSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRG 205
S SS + + + +SS S S+ D + SS +S
Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNS 752
Query: 206 SLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSSKN 258
S + S + + DS DS S+ DS+ SS S+ + + S +S S N
Sbjct: 753 S-DSSDSSDSSNSSDSSDSSDSS----DSSDSS-NSSDSNDSSNSSDSSDSSN 799
Score = 54.3 bits (129), Expect = 3e-07
Identities = 42/176 (23%), Positives = 63/176 (35%), Gaps = 1/176 (0%)
Query: 83 SEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSP 142
S S +S+ + + + + + E D SS S + S + S S SSD + S +
Sbjct: 607 SSDSSDSSDSSDSSDSKSDSSKSESD-SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665
Query: 143 GAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGG 202
+S SS D + S SS SS S D S++ S
Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725
Query: 203 RRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSSKN 258
S S S S+ S SS D + S S+ + + S +S S N
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781
Score = 53.9 bits (128), Expect = 3e-07
Identities = 51/204 (25%), Positives = 74/204 (36%), Gaps = 9/204 (4%)
Query: 64 GGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDD-EEEEDESSSSGGGEEESSA 122
G G G ++ + S + DE DD E D +SSS G +S
Sbjct: 437 GHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSD 496
Query: 123 ESLVGSSG----GSSSDETRSLSPGAASSSSGDG----DGKEGLEEPKGPRGSQGGGGGG 174
ES +G G+ D++ S S S S+G+G D + + KG S
Sbjct: 497 ESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSD 556
Query: 175 SSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDS 234
SS+SS S D S + S S SD S S + DS
Sbjct: 557 SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS 616
Query: 235 TISSGRSTPAMMNGQGSTTSSSKN 258
+ SS + + + S+ S SK+
Sbjct: 617 SDSSDSKSDSSKSESDSSDSDSKS 640
Score = 53.9 bits (128), Expect = 3e-07
Identities = 51/258 (19%), Positives = 87/258 (33%), Gaps = 7/258 (2%)
Query: 6 TDMADLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGG 65
+D ++ + S S S S + + + ++ + ++ N
Sbjct: 948 SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS 1007
Query: 66 GGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEES----- 120
++ S+ S S S D + D + D S SS +S
Sbjct: 1008 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSN--SSDSSDSSD 1065
Query: 121 SAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSV 180
S++S S SSD + S +S+SS D + + S SS+SS
Sbjct: 1066 SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1125
Query: 181 VSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGR 240
S D + SS +S S S S S+ S SS D ++ S
Sbjct: 1126 SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185
Query: 241 STPAMMNGQGSTTSSSKN 258
S+ + + S +S S +
Sbjct: 1186 SSDSSDSSDSSDSSDSSD 1203
Score = 53.5 bits (127), Expect = 4e-07
Identities = 44/176 (25%), Positives = 66/176 (37%), Gaps = 3/176 (1%)
Query: 83 SEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSP 142
S S +S + + + + + SS S + S ++S S +SSD + S +
Sbjct: 779 SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS 838
Query: 143 GAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGG 202
+S SS DG + + S SS SS S D SS +S
Sbjct: 839 SDSSDSSDSSDGSDS-DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS 897
Query: 203 RRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSSKN 258
S SSD S DS DS +S+ S S ++ N S+ SS +
Sbjct: 898 SNSSDSDSSDSSNSS--DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951
Score = 53.5 bits (127), Expect = 4e-07
Identities = 36/186 (19%), Positives = 63/186 (33%), Gaps = 2/186 (1%)
Query: 6 TDMADLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGG 65
+D +D S S S S + ++ + E + + +++ + +
Sbjct: 1115 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSS--DSSDSS 1172
Query: 66 GGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESL 125
++ S+ S S S D + D + D S SS + S++S
Sbjct: 1173 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN 1232
Query: 126 VGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGG 185
S SSD + S + +S SS D + + G G S S S G
Sbjct: 1233 ESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGS 1292
Query: 186 DEGYGT 191
D + T
Sbjct: 1293 DSNHST 1298
Score = 52.4 bits (124), Expect = 1e-06
Identities = 45/184 (24%), Positives = 67/184 (36%), Gaps = 3/184 (1%)
Query: 78 EAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSS-GGGEEES--SAESLVGSSGGSSS 134
E+ S+ S S S D + D + D S SS +S S++S S +SS
Sbjct: 1083 ESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 1142
Query: 135 DETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGG 194
D + S +S SS D + + S SS SS S D +
Sbjct: 1143 DSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1202
Query: 195 GSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTS 254
SS +S S S S S+ + SS D + S S+ + + S ++
Sbjct: 1203 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDST 1262
Query: 255 SSKN 258
S N
Sbjct: 1263 SDSN 1266
Score = 51.2 bits (121), Expect = 2e-06
Identities = 43/186 (23%), Positives = 67/186 (36%), Gaps = 5/186 (2%)
Query: 78 EAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDET 137
++++ S S S S D + + D S SS + SS++S S SSD +
Sbjct: 637 DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696
Query: 138 RSL-SPGAASSSSGD----GDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTG 192
S S ++ SS D D S +SS S SS +
Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756
Query: 193 GGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGST 252
S+ S S + S + + DS DS +S+ S S ++ + S+
Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816
Query: 253 TSSSKN 258
S S N
Sbjct: 817 DSDSSN 822
Score = 50.4 bits (119), Expect = 4e-06
Identities = 46/184 (25%), Positives = 64/184 (34%), Gaps = 4/184 (2%)
Query: 78 EAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGG-EEES--SAESLVGSSGGSSS 134
++ S+ S S S D + D D S SS +S S++S S SS
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154
Query: 135 DETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGG 194
D + S +S SS D + S SS SS S D +
Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1214
Query: 195 GSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTS 254
SS +S S + S E DS DS S+ S S + + N + + S
Sbjct: 1215 DSSDSSDSSDSS-DSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQS 1273
Query: 255 SSKN 258
S N
Sbjct: 1274 KSGN 1277
Score = 48.5 bits (114), Expect = 1e-05
Identities = 39/204 (19%), Positives = 74/204 (36%), Gaps = 1/204 (0%)
Query: 78 EAETMSEPSPES-ASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDE 136
++ S+ S S +S + D + + + +SS+S S + SS S S +
Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD 846
Query: 137 TRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGS 196
+ S +S+ S + + + S S+ SS S D + S
Sbjct: 847 SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS 906
Query: 197 SATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSS 256
+++ SSD S + S + DS+ SS S + + +++SS
Sbjct: 907 DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966
Query: 257 KNIAYNCCWDQCQACFNSSPDLAD 280
+ N + + S D +D
Sbjct: 967 DSSDSNSSDSSDSSNSSDSSDSSD 990
Score = 46.2 bits (108), Expect = 7e-05
Identities = 47/181 (25%), Positives = 65/181 (35%), Gaps = 15/181 (8%)
Query: 83 SEPSPESA-SQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLS 141
SEP + S G D + + D + D+ S G + SS ES S SD
Sbjct: 430 SEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGD-DPNSSDESNGNDDANSESDNN---- 484
Query: 142 PGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGS----S 197
SSS GD + G GS G S S + + G G G+
Sbjct: 485 ----SSSRGDASYNSDESKDNG-NGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDK 539
Query: 198 ATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSSK 257
+ SG + S + + DS DS S D +S+ S S + S +S S
Sbjct: 540 SDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSS 599
Query: 258 N 258
N
Sbjct: 600 N 600
Score = 43.9 bits (102), Expect = 4e-04
Identities = 37/147 (25%), Positives = 53/147 (36%), Gaps = 4/147 (2%)
Query: 78 EAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDET 137
++ S+ S S S D D + D S SS +SS +S S SSD +
Sbjct: 1158 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD--SSDSS-DSSDSSDSSDSSDSS 1214
Query: 138 RSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSS 197
S +S SS D E + S SS SS S + S
Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274
Query: 198 ATSGGRRGS-LEMSSDGEPLSRMDSED 223
+ +G GS + S+G + S+D
Sbjct: 1275 SGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 38.9 bits (89), Expect = 0.011
Identities = 36/151 (23%), Positives = 58/151 (38%), Gaps = 6/151 (3%)
Query: 7 DMADLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGG 66
D+ D ++ + P A + E+E E E + + + +G
Sbjct: 166 DVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTK 225
Query: 67 GGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEE-DDEEEEDESSSSGGGEEESSAESL 125
G G S+ SP S + A EDEDE DDE+EE + G + ++++
Sbjct: 226 EAEVTPGTGEDAGLDNSDGSP-SGNGADEDEDEGSGDDEDEE----AGNGKDSSNNSKGQ 280
Query: 126 VGSSGGSSSDETRSLSPGAASSSSGDGDGKE 156
G G D S+ + S D +GKE
Sbjct: 281 EGQDHGKEDDHDSSIGQNSDSKEYYDPEGKE 311
Score = 33.1 bits (74), Expect = 0.63
Identities = 39/205 (19%), Positives = 74/205 (36%), Gaps = 10/205 (4%)
Query: 85 PSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSL---S 141
PS + + E E E++ G G ++ E + G S+ + +
Sbjct: 381 PSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSN 440
Query: 142 PGAASSSSG------DGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGG 195
G+ S+S G D +G ++P S G S S + SS GD Y +
Sbjct: 441 TGSDSNSDGYDSYDFDDKSMQG-DDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESK 499
Query: 196 SSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSS 255
+ +G+ + SD + + + D + SG+ + S +S+
Sbjct: 500 DNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSN 559
Query: 256 SKNIAYNCCWDQCQACFNSSPDLAD 280
S + + + D + +S D +D
Sbjct: 560 SSDSSDSSDSDSSDSNSSSDSDSSD 584
Score = 32.7 bits (73), Expect = 0.82
Identities = 57/279 (20%), Positives = 89/279 (31%), Gaps = 53/279 (18%)
Query: 22 PGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAET 81
PG+ A ++ +E+E+E + NG G G G+
Sbjct: 231 PGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGK--- 287
Query: 82 MSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVG---SSGGSSSDETR 138
E +S+ D E D E +ED + G + S E+ G +G ++T+
Sbjct: 288 --EDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQ 345
Query: 139 SL----------------------------------SPGAASSSSGDGDGKEGLEEPKGP 164
L S G + + G G EG +E KG
Sbjct: 346 KLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEG-KEDKGQ 404
Query: 165 RGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDS 224
G G G + VV+ G G + G + G SD DS D
Sbjct: 405 HGMILGKGNVKTQGEVVN--------IEGPGQKSEPGNKVGHSNTGSDSNS-DGYDSYDF 455
Query: 225 ISSTIMDVDSTISSGRSTPAMMNGQGSTTSSSK-NIAYN 262
++ D S + N + SSS+ + +YN
Sbjct: 456 DDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYN 494
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 64.7 bits (156), Expect = 2e-10
Identities = 50/143 (34%), Positives = 54/143 (37%), Gaps = 17/143 (11%)
Query: 61 GGSGG--GGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEE 118
GGSGG GGGG GGG GGG S S+ G SGGG
Sbjct: 491 GGSGGSYGGGGSGGGYGGG-----------SGSRGGSGGSYGGGS----GSGGGSGGGYG 535
Query: 119 ESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSS 178
S G SGG S + G + S G G G G +G G GGG G
Sbjct: 536 GGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGE 595
Query: 179 SVVSSGGDEGYGTGGGGSSATSG 201
S S GG E GGG SG
Sbjct: 596 SGGSYGGGEEASGSGGGYGGGSG 618
Score = 53.5 bits (127), Expect = 4e-07
Identities = 50/155 (32%), Positives = 58/155 (37%), Gaps = 3/155 (1%)
Query: 67 GGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLV 126
GGGGGGG+G G + S S+ G S G G S S
Sbjct: 15 GGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYG 74
Query: 127 GSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGD 186
G SGG S SL G S G G G G G GGG G SG
Sbjct: 75 GGSGGGFS--ASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFG 132
Query: 187 EGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDS 221
G+G GGG+ GG + E S+ E SR+ S
Sbjct: 133 -GFGGFGGGAGGGDGGILTANEKSTMQELNSRLAS 166
Score = 52.0 bits (123), Expect = 1e-06
Identities = 52/172 (30%), Positives = 58/172 (33%), Gaps = 56/172 (32%)
Query: 43 EEEEEEAEAEAVAALLLNGGSGGGG-------GGGGGGVGGGEAETMSEPSPESASQAGE 95
E +E+ E+ + L G G GG GG GG GGG
Sbjct: 459 EGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGG------------------ 500
Query: 96 DEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGK 155
SGGG S GS GGS G+ SG G G
Sbjct: 501 ----------------GSGGGYGGGS-----GSRGGSG---------GSYGGGSGSGGGS 530
Query: 156 EGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTG-GGGSSATSGGRRGS 206
G G GG GGG S S + GG G G G GGG SG R GS
Sbjct: 531 GGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGS 582
Score = 51.2 bits (121), Expect = 2e-06
Identities = 58/182 (31%), Positives = 73/182 (40%), Gaps = 32/182 (17%)
Query: 60 NGGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEE 119
+GG GGGG G GG + S S S+S G SSSSG G
Sbjct: 14 SGGGGGGGLGSGGSI-------RSSYSRFSSSGGGGGGGR---------FSSSSGYG--- 54
Query: 120 SSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSS 179
+ + G GG S + G S+S G G G G RG G GGG SSS
Sbjct: 55 GGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGG-----GSRGFGGASGGGYSSSG 109
Query: 180 VVSS--GGDEGYGTGGGGSSATSG-GRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTI 236
GG G G GGG S G G G DG L+ + ST+ +++S +
Sbjct: 110 GFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANE-----KSTMQELNSRL 164
Query: 237 SS 238
+S
Sbjct: 165 AS 166
Score = 42.7 bits (99), Expect = 8e-04
Identities = 29/75 (38%), Positives = 30/75 (40%), Gaps = 1/75 (1%)
Query: 139 SLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSA 198
+L G G GK GL G GS G G G S S G GYG GG GS
Sbjct: 456 NLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYG-GGSGSRG 514
Query: 199 TSGGRRGSLEMSSDG 213
SGG G S G
Sbjct: 515 GSGGSYGGGSGSGGG 529
Score = 38.5 bits (88), Expect = 0.015
Identities = 26/74 (35%), Positives = 29/74 (39%), Gaps = 12/74 (16%)
Query: 61 GGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEES 120
GGSG GGG GGG GG S S+ G + S GGGEE S
Sbjct: 560 GGSGSGGGSGGGYGGG------------SGSRGGSGGSHGGGSGFGGESGGSYGGGEEAS 607
Query: 121 SAESLVGSSGGSSS 134
+ G G SS
Sbjct: 608 GSGGGYGGGSGKSS 621
Score = 34.7 bits (78), Expect = 0.22
Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 4/53 (7%)
Query: 61 GGSGGGGGGGGGGVGG----GEAETMSEPSPESASQAGEDEDEEEDDEEEEDE 109
GG GG GGG GGG GG E TM E + AS + + EE + + E++
Sbjct: 132 GGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANNDLENK 184
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 64.7 bits (156), Expect = 2e-10
Identities = 67/217 (30%), Positives = 80/217 (36%), Gaps = 45/217 (20%)
Query: 61 GGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEES 120
G SGGGGGGG GG GGG ++ +S G SSGGG
Sbjct: 67 GSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSG-------------CFSSGGGGSGC 113
Query: 121 SAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSV 180
+ GSSGG S G SS G G G G GGGG S +V
Sbjct: 114 FSSGGGGSSGGGS---------GCFSSGGGGSSG--------GGSGCFSSGGGGFSGQAV 156
Query: 181 -------VSSGGDEGYGTG-----GGGSS--ATSGGRRGSLEMSSDGEPLSRMDSEDSIS 226
VSSGG G G+G GGG S SGG G SS G + S+ ++
Sbjct: 157 QCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQ-QVT 215
Query: 227 STIMDVDSTISSGRSTPAMMNGQGSTTSSSKNIAYNC 263
T + G S G G +S + C
Sbjct: 216 QTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGC 252
Score = 59.7 bits (143), Expect = 6e-09
Identities = 55/169 (32%), Positives = 63/169 (37%), Gaps = 42/169 (24%)
Query: 44 EEEEEAEAEAVAALLLNGGSGGGGGGGGGGVG--GGEAETMSEPSPESASQAGEDEDEEE 101
++++ V + +GG GGGGG GGGG G GG S G
Sbjct: 4 QKKQPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGG-----------GGSGGG------- 45
Query: 102 DDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEP 161
SS SG G S G GGSS G G G G G +
Sbjct: 46 --------SSGSGCGYSGGGGYSGGGCGGGSSGG-------GGGGGIGGCGGGSGGSVKY 90
Query: 162 KGPRGSQGGGGG----GSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGS 206
G GS GGG G G S SSGG G+ GGGS S G GS
Sbjct: 91 SGGGGSSGGGSGCFSSGGGGSGCFSSGGG---GSSGGGSGCFSSGGGGS 136
Score = 57.4 bits (137), Expect = 3e-08
Identities = 51/159 (32%), Positives = 59/159 (37%), Gaps = 14/159 (8%)
Query: 61 GGSGGGGGG----GGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEE------EDES 110
GGS GGG G GGGG G + S S +G
Sbjct: 134 GGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGG 193
Query: 111 SSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGG 170
S GGG S V S + + S G SS G G G G G GS G
Sbjct: 194 SGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGG-GSGGSGCFSSGGGGGSSGC 252
Query: 171 GGG--GSSSSSVVSSGGDE-GYGTGGGGSSATSGGRRGS 206
GGG G S ++S GG G G+ GGG +S G GS
Sbjct: 253 GGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGS 291
Score = 49.3 bits (116), Expect = 8e-06
Identities = 45/137 (32%), Positives = 52/137 (37%), Gaps = 32/137 (23%)
Query: 63 SGGGGG------GGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGG 116
SGGGGG GGG G GGG S+ +G + + S GG
Sbjct: 179 SGGGGGSVCGYSGGGSGCGGG-----------SSGGSGSGYVSSQQVTQTSCAPQPSYGG 227
Query: 117 EEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEP---KGPRGSQGGG-- 171
GSSGG S + S G SSG G G G+ G GGG
Sbjct: 228 ----------GSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSS 277
Query: 172 GGGSSSSSVVSSGGDEG 188
GGG SSV SG +G
Sbjct: 278 GGGGGGSSVGGSGSGKG 294
>gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens]
Length = 508
Score = 64.3 bits (155), Expect = 3e-10
Identities = 91/327 (27%), Positives = 124/327 (37%), Gaps = 54/327 (16%)
Query: 59 LNGGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEE-------EDDEEEEDESS 111
++GGSGGGGGGGGGG + +P S D + E + S
Sbjct: 151 VSGGSGGGGGGGGGGSSAHSQDGSHQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPS 210
Query: 112 SSGGGEEESSAESLVGSSGGSSSDETRS-----LSPGAASSSSGD-----GDGKEGLEEP 161
G G A VGS+G SS + + +P +A++ G G + L P
Sbjct: 211 HPGLG-----AAGEVGSAGASSWWDVGAGWIDVQNPNSAAALPGSLHPAAGGLQTSLHSP 265
Query: 162 KGPRGSQGGGGGGSSSSSVVSS-----------GGDEGYGTGGGGSSATS--GGRRGSLE 208
G S G S+ SS SS G + G SA S G GS+
Sbjct: 266 LGGYNSDYSGLSHSAFSSGASSHLLSPAGQHLMDGFKPVLPGSYPDSAPSPLAGAGGSML 325
Query: 209 MSSDGEPLS---RMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSSKNIAYNCCW 265
+ PL R + D + + R PA S + ++C
Sbjct: 326 SAGPSAPLGGSPRSSARRYSGRATCDCPNCQEAERLGPA-------GASLRRKGLHSCHI 378
Query: 266 DQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGD 325
C + + L H+R H G+R FVC W C T S LQRH+ TH+G+
Sbjct: 379 PGCGKVYGKTSHLKAHLRW-HT-GERP--FVCNWLFCGKRFTRSDE---LQRHLRTHTGE 431
Query: 326 KPFKCVVGGCNASFASQGGLARHVPTH 352
K F C V CN F L++HV TH
Sbjct: 432 KRFACPV--CNKRFMRSDHLSKHVKTH 456
Score = 42.7 bits (99), Expect = 8e-04
Identities = 42/163 (25%), Positives = 64/163 (39%), Gaps = 17/163 (10%)
Query: 23 GSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETM 82
GSP + ++ + + + + + A+ + G S G G GG +
Sbjct: 28 GSPSPSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAA 87
Query: 83 SEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSP 142
+ + +A+ A D S S GG SSA SL SS +++ +
Sbjct: 88 AAAAAAAAAAAALVSD------------SFSCGGSPGSSAFSLTSSSAAAAA-----AAA 130
Query: 143 GAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGG 185
AA+SSS + + P GS GGGGGG SS S G
Sbjct: 131 AAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHSQDG 173
Score = 33.1 bits (74), Expect = 0.63
Identities = 34/142 (23%), Positives = 49/142 (34%), Gaps = 13/142 (9%)
Query: 85 PSPESASQAGEDEDEEEDDEEEEDESSSSG----GGEEESSAESLVGSSGGSSSDETRSL 140
PSP S S + + + SSS+ G S S +GGSSS +
Sbjct: 32 PSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAAA 91
Query: 141 SPGAASS-------SSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGD--EGYGT 191
+ AA++ S G G + ++SSS ++ + G
Sbjct: 92 AAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGV 151
Query: 192 GGGGSSATSGGRRGSLEMSSDG 213
GG GG GS S DG
Sbjct: 152 SGGSGGGGGGGGGGSSAHSQDG 173
Score = 30.4 bits (67), Expect = 4.1
Identities = 14/29 (48%), Positives = 16/29 (55%)
Query: 63 SGGGGGGGGGGVGGGEAETMSEPSPESAS 91
SGGGGGGG G G G + S SA+
Sbjct: 457 SGGGGGGGSAGSGSGGKKGSDTDSEHSAA 485
>gi|39812501 Sp8 transcription factor isoform 2 [Homo sapiens]
Length = 490
Score = 64.3 bits (155), Expect = 3e-10
Identities = 91/327 (27%), Positives = 124/327 (37%), Gaps = 54/327 (16%)
Query: 59 LNGGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEE-------EDDEEEEDESS 111
++GGSGGGGGGGGGG + +P S D + E + S
Sbjct: 133 VSGGSGGGGGGGGGGSSAHSQDGSHQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPS 192
Query: 112 SSGGGEEESSAESLVGSSGGSSSDETRS-----LSPGAASSSSGD-----GDGKEGLEEP 161
G G A VGS+G SS + + +P +A++ G G + L P
Sbjct: 193 HPGLG-----AAGEVGSAGASSWWDVGAGWIDVQNPNSAAALPGSLHPAAGGLQTSLHSP 247
Query: 162 KGPRGSQGGGGGGSSSSSVVSS-----------GGDEGYGTGGGGSSATS--GGRRGSLE 208
G S G S+ SS SS G + G SA S G GS+
Sbjct: 248 LGGYNSDYSGLSHSAFSSGASSHLLSPAGQHLMDGFKPVLPGSYPDSAPSPLAGAGGSML 307
Query: 209 MSSDGEPLS---RMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSSKNIAYNCCW 265
+ PL R + D + + R PA S + ++C
Sbjct: 308 SAGPSAPLGGSPRSSARRYSGRATCDCPNCQEAERLGPA-------GASLRRKGLHSCHI 360
Query: 266 DQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGD 325
C + + L H+R H G+R FVC W C T S LQRH+ TH+G+
Sbjct: 361 PGCGKVYGKTSHLKAHLRW-HT-GERP--FVCNWLFCGKRFTRSDE---LQRHLRTHTGE 413
Query: 326 KPFKCVVGGCNASFASQGGLARHVPTH 352
K F C V CN F L++HV TH
Sbjct: 414 KRFACPV--CNKRFMRSDHLSKHVKTH 438
Score = 42.7 bits (99), Expect = 8e-04
Identities = 42/163 (25%), Positives = 64/163 (39%), Gaps = 17/163 (10%)
Query: 23 GSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETM 82
GSP + ++ + + + + + A+ + G S G G GG +
Sbjct: 10 GSPSPSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAA 69
Query: 83 SEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSP 142
+ + +A+ A D S S GG SSA SL SS +++ +
Sbjct: 70 AAAAAAAAAAAALVSD------------SFSCGGSPGSSAFSLTSSSAAAAA-----AAA 112
Query: 143 GAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGG 185
AA+SSS + + P GS GGGGGG SS S G
Sbjct: 113 AAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHSQDG 155
Score = 33.1 bits (74), Expect = 0.63
Identities = 34/142 (23%), Positives = 49/142 (34%), Gaps = 13/142 (9%)
Query: 85 PSPESASQAGEDEDEEEDDEEEEDESSSSG----GGEEESSAESLVGSSGGSSSDETRSL 140
PSP S S + + + SSS+ G S S +GGSSS +
Sbjct: 14 PSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAAA 73
Query: 141 SPGAASS-------SSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGD--EGYGT 191
+ AA++ S G G + ++SSS ++ + G
Sbjct: 74 AAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGV 133
Query: 192 GGGGSSATSGGRRGSLEMSSDG 213
GG GG GS S DG
Sbjct: 134 SGGSGGGGGGGGGGSSAHSQDG 155
Score = 30.4 bits (67), Expect = 4.1
Identities = 14/29 (48%), Positives = 16/29 (55%)
Query: 63 SGGGGGGGGGGVGGGEAETMSEPSPESAS 91
SGGGGGGG G G G + S SA+
Sbjct: 439 SGGGGGGGSAGSGSGGKKGSDTDSEHSAA 467
>gi|110431364 GLIS family zinc finger 2 [Homo sapiens]
Length = 524
Score = 64.3 bits (155), Expect = 3e-10
Identities = 48/197 (24%), Positives = 80/197 (40%), Gaps = 40/197 (20%)
Query: 195 GSSATSGGRRGSLEM-----SSDGEPLSRMDSEDSISSTIMDVDS-----TISSGRSTPA 244
GSS+ S R+G+ ++ +SD +PL +D S + + S +S TP
Sbjct: 94 GSSSLSPERQGNGDLPPVPSASDFQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLTPP 153
Query: 245 MMNGQGSTTSSSKNIAYNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGC-- 302
K + C W +C F DL DH+ HV ++ + C W+GC
Sbjct: 154 KDKCLSPDLPLPKQLV--CRWAKCNQLFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCAR 211
Query: 303 ---------------------KVYNTPSTSQSW-----LQRHMLTHSGDKPFKCVVGGCN 336
K + P+ S+S+ L+ H +H+G+KP+ C GCN
Sbjct: 212 HGRGFNARYKMLIHIRTHTNEKPHRCPTCSKSFSRLENLKIHNRSHTGEKPYVCPYEGCN 271
Query: 337 ASFASQGGLARHVPTHF 353
+++ +H TH+
Sbjct: 272 KRYSNSSDRFKHTRTHY 288
Score = 30.4 bits (67), Expect = 4.1
Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 261 YNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGC-KVYNTPSTSQSWLQRH 318
Y C ++ C +++S D H R+ +VD + C GC K Y PS+ + ++ H
Sbjct: 263 YVCPYEGCNKRYSNSSDRFKHTRTHYVDKP----YYCKMPGCHKRYTDPSSLRKHIKAH 317
>gi|170650685 zinc finger and BTB domain containing 37 isoform a
[Homo sapiens]
Length = 503
Score = 62.4 bits (150), Expect = 1e-09
Identities = 94/324 (29%), Positives = 125/324 (38%), Gaps = 59/324 (18%)
Query: 84 EPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPG 143
E SP S + + + D E E + G+ E+ V GG S DE R L G
Sbjct: 186 ELSPPEESTSPQIIEPSSDVESREPILRINRAGQWY--VETGVADRGGRSDDEVRVL--G 241
Query: 144 AASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVS---------SGGDEGYGTGGG 194
A + E LEE GP +Q G GSS+ V + S G E Y G
Sbjct: 242 AVHIKT------ENLEEWLGPE-NQPSGEDGSSAEEVTAMVIDTTGHGSVGQENYTLGSS 294
Query: 195 GSSATSGGRRGSLEMSSDGE--PLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQG-- 250
G+ S G PL+ S S MD SS AMM G
Sbjct: 295 GAKVARPTSSEVDRFSPSGSVVPLTERHRARSESPGRMDEPKQPSSQVEESAMMGVSGYV 354
Query: 251 ----STTSSSKNIAYN----CCWDQCQACFNSSPDLADHIRSIHVDGQRGGV--FVCLWK 300
S + YN C + C FN L H+R +H+ G+ FVC
Sbjct: 355 EYLREQEVSERWFRYNPRLTCIY--CAKSFNQKGSLDRHMR-LHM-----GITPFVCRMC 406
Query: 301 GCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARH--------VPTH 352
G K T + L+ H+ H+G+KPF C V C SF Q L +H +P
Sbjct: 407 GKKY-----TRKDQLEYHIRKHTGNKPFHCHV--CGKSFPFQAILNQHFRKNHPGCIPLE 459
Query: 353 --FSQQNSSKVSSQPKAKEESPSK 374
S + V+S+ +A+EESPS+
Sbjct: 460 GPHSISPETTVTSRGQAEEESPSQ 483
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 61.6 bits (148), Expect = 2e-09
Identities = 57/171 (33%), Positives = 63/171 (36%), Gaps = 54/171 (31%)
Query: 60 NGGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEE 119
N SGGGGGGGGGG G +D+SS S GG
Sbjct: 162 NSSSGGGGGGGGGGNYG------------------------------QDQSSMSSGG--- 188
Query: 120 SSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKG-PRGSQGGGGGGSSSS 178
GS GG G S G G G G ++ G RG GGGGGG
Sbjct: 189 -------GSGGGY----------GNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGG 231
Query: 179 SVVSSGGDEGYGTGG--GGSSATSGGRRGSL-EMSSDGEPLSRMDSEDSIS 226
SSGG E G GG GG G RG + + SR DSE S
Sbjct: 232 YNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNS 282
Score = 43.9 bits (102), Expect = 4e-04
Identities = 38/129 (29%), Positives = 51/129 (39%), Gaps = 15/129 (11%)
Query: 61 GGSGGGGGGG---GGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGE 117
GGSGGGG GG GGG GGG+ P + E ++ + + GGG
Sbjct: 400 GGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGP 459
Query: 118 EESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSS 177
S GG+ D+ R G G G+ G + G RG +GGG G
Sbjct: 460 GGS-------HMGGNYGDDRRG---GRGGYDRGGYRGRGG--DRGGFRGGRGGGDRGGFG 507
Query: 178 SSVVSSGGD 186
+ S G+
Sbjct: 508 PGKMDSRGE 516
Score = 42.7 bits (99), Expect = 8e-04
Identities = 44/177 (24%), Positives = 60/177 (33%), Gaps = 41/177 (23%)
Query: 83 SEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEE--SSAESLVGSSGGSSS------ 134
++ +P+ G + +SS G G++ SS GSS SSS
Sbjct: 68 TQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQS 127
Query: 135 ----------------DETRSLSP----------GAASSSSGDGDGKEGLEEPKGPRGSQ 168
+ +S +P ++S G G G + + S
Sbjct: 128 GSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSG 187
Query: 169 GGGGGGSSSSSVVSSGGDEGY------GTGGGGSSATSGGRRGSLEMSSDG-EPLSR 218
GG GGG + GG GY G G GGS GG G SS G EP R
Sbjct: 188 GGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGR 244
Score = 42.4 bits (98), Expect = 0.001
Identities = 56/207 (27%), Positives = 78/207 (37%), Gaps = 55/207 (26%)
Query: 61 GGSGGGGGGGGGGV------------GGGEAET--MSEPSPESASQAGEDEDEEEDDEEE 106
GGSGGGGGGGGGG GGG M ++ G D+ + E
Sbjct: 219 GGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSE 278
Query: 107 EDESSSS-----GGGEE---ESSAESL--VG-------------------SSGGSSSDET 137
+D S ++ G GE ES A+ +G +G + T
Sbjct: 279 QDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEAT 338
Query: 138 RSLS-PGAASSSSGDGDGKEGLEEP-------KGPRGSQGGGGG--GSSSSSVVSSGGDE 187
S P +A ++ DGKE P + ++GGG G G + GG
Sbjct: 339 VSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYG 398
Query: 188 GYGTGGGGSSA--TSGGRRGSLEMSSD 212
G G+GGGG + GG G + + D
Sbjct: 399 GGGSGGGGRGGFPSGGGGGGGQQRAGD 425
Score = 39.3 bits (90), Expect = 0.009
Identities = 34/106 (32%), Positives = 43/106 (40%), Gaps = 2/106 (1%)
Query: 114 GGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGG 173
G G + S++ S S T + G +S SS G P+G GG
Sbjct: 22 GQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGY 81
Query: 174 GSSSSSVVSSGGDEGYGTGG--GGSSATSGGRRGSLEMSSDGEPLS 217
GSS SS S G Y G S+TSG S + SS G+P S
Sbjct: 82 GSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQS 127
Score = 33.5 bits (75), Expect = 0.48
Identities = 43/161 (26%), Positives = 52/161 (32%), Gaps = 35/161 (21%)
Query: 61 GGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEED----DEEEEDESSSSGGG 116
GG G GG G GG GGG + S G + D + E+ + S
Sbjct: 384 GGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNE 443
Query: 117 EEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSS 176
+ A G GG PG + GD + GG GG
Sbjct: 444 CNQCKAPKPDGPGGG----------PGGSHMGGNYGDDRR-------------GGRGGYD 480
Query: 177 SSSVVSSGGDEGYGTGGGGSSATSGGRRGSL---EMSSDGE 214
GGD G GG G GG RG +M S GE
Sbjct: 481 RGGYRGRGGDRGGFRGGRG-----GGDRGGFGPGKMDSRGE 516
>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
Length = 686
Score = 60.8 bits (146), Expect = 3e-09
Identities = 64/209 (30%), Positives = 82/209 (39%), Gaps = 27/209 (12%)
Query: 22 PGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAET 81
PG PG AA G AE PE E EE A A A GGGG G EAE
Sbjct: 28 PGEPG-AAGGEAEGPEGSEGAEEAPRGAAAVKEA-------------GGGGPDRGPEAEA 73
Query: 82 MSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSS-GGSSSDETRSL 140
+ GE E EE E E GGEE S A+ + G+S G + E R
Sbjct: 74 RG-----TRGAHGETEAEEGAPEGAEVPQ----GGEETSGAQQVEGASPGRGAQGEPRGE 124
Query: 141 SPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATS 200
+ S+ +E + P+ P GS G G S + GD G G S +
Sbjct: 125 AQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAE--GPLGDNIEAEGPAGDSVEA 182
Query: 201 GGRRGSLEMSSDGEPLSRMDSEDSISSTI 229
GR G + ++G +D+E + I
Sbjct: 183 EGRVGD-SVDAEGPAGDSVDAEGPLGDNI 210
Score = 50.1 bits (118), Expect = 5e-06
Identities = 60/235 (25%), Positives = 84/235 (35%), Gaps = 17/235 (7%)
Query: 12 EELSRLSPLPPGSPGSAA----RGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGG 67
EE S + SPG A RG A+ E+ E +EEAE G G
Sbjct: 100 EETSGAQQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDS 159
Query: 68 GGGGGGVGGG-EAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLV 126
G +G EAE + S E+ + G+ D E + D G + AE
Sbjct: 160 VDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLG---DNIQAEGPA 216
Query: 127 GSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGD 186
G S + S+ + S D +G+ G G G G + SV +
Sbjct: 217 GDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAE--- 273
Query: 187 EGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRS 241
G G S + G G S GEP D S + ++V + S+GRS
Sbjct: 274 -----GPAGDSMDAEGPAGRARRVS-GEPQQSGDGSLSPQAEAIEVAAGESAGRS 322
Score = 44.3 bits (103), Expect = 3e-04
Identities = 52/213 (24%), Positives = 75/213 (35%), Gaps = 7/213 (3%)
Query: 21 PPGSPGS--AARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGE 78
P GS G+ A RG A E + EAEA + G G GGE
Sbjct: 41 PEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGE 100
Query: 79 AETMSEPSPESAS--QAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDE 136
ET E AS + + E E E ED ++ E E E GS+ G + D
Sbjct: 101 -ETSGAQQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDS 159
Query: 137 TRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGS 196
+ P + +G + +E S G S GD G G
Sbjct: 160 VDAEGP-LGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGD 218
Query: 197 SATSGGRRGSLEMSSDGEPLSRMDSEDSISSTI 229
S + GR G + ++G +D+E + ++
Sbjct: 219 SVDAEGRVGD-SVDAEGPAGDSVDAEGRVGDSV 250
Score = 40.0 bits (92), Expect = 0.005
Identities = 44/151 (29%), Positives = 58/151 (38%), Gaps = 24/151 (15%)
Query: 23 GSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETM 82
G G A R EP ++ + +AEA VAA G S G G EAE
Sbjct: 284 GPAGRARRVSGEP--QQSGDGSLSPQAEAIEVAA----GESAGRSPGELAWDAAEEAEVP 337
Query: 83 SEPSPESAS------QAGEDE-----DEEEDDEEEEDESSSSG-------GGEEESSAES 124
E A+ AGED +E ++EE E S G GGEEES S
Sbjct: 338 GVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSS 397
Query: 125 LVGSSGGSSSDETRSLSPGAASSSSGDGDGK 155
G + +++ LS A +G G+
Sbjct: 398 PHGEASRGAAEPEAQLSNHLAEEGPAEGSGE 428
Score = 35.4 bits (80), Expect = 0.13
Identities = 60/240 (25%), Positives = 79/240 (32%), Gaps = 63/240 (26%)
Query: 22 PGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAET 81
P A GR + E + +AE G S G G GV EA
Sbjct: 215 PAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRV-------GDSVEAGDPAGDGV---EAGV 264
Query: 82 MSEPSPESASQAGEDEDEEED---DEEEEDESSSSGGGEEESSAESL---VGSSGGSSSD 135
+ S E+ AG+ D E E SG G AE++ G S G S
Sbjct: 265 PAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPG 324
Query: 136 E----------------TRSLSPGAASSSSGD---GDGKE---GLEE------PKGPRGS 167
E + +PG A + +G+ GDG + G +E P+GPR
Sbjct: 325 ELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREE 384
Query: 168 QGGGGGGSSSSSVVSSGGDEGYGTG-----------------GGGSSATSGGRRGSLEMS 210
+ GG S S S G+ G G G +A GRR E S
Sbjct: 385 EAAGGEEESPDS--SPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEAS 442
Score = 32.7 bits (73), Expect = 0.82
Identities = 25/107 (23%), Positives = 37/107 (34%), Gaps = 5/107 (4%)
Query: 87 PESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAAS 146
PE + E E E + S G EE + V +GG D
Sbjct: 18 PEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTR 77
Query: 147 SSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGG 193
+ G+ + +EG P G++ GG +S + G G G G
Sbjct: 78 GAHGETEAEEG-----APEGAEVPQGGEETSGAQQVEGASPGRGAQG 119
Score = 30.8 bits (68), Expect = 3.1
Identities = 38/138 (27%), Positives = 48/138 (34%), Gaps = 20/138 (14%)
Query: 22 PGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAET 81
PG A AE P + EE +A A+A G G G GE E
Sbjct: 323 PGELAWDAAEEAEVPGVKGSEEAAPGDARADA----------GEDRVGDGPQQEPGEDEE 372
Query: 82 MSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLS 141
E SPE EEE EE+ SS GE A ++E +
Sbjct: 373 RRERSPEGPR-------EEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEG 425
Query: 142 PGAASSSSG---DGDGKE 156
G A+ +G DG+ E
Sbjct: 426 SGEAARVNGRREDGEASE 443
>gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein
[Homo sapiens]
Length = 593
Score = 60.1 bits (144), Expect = 5e-09
Identities = 59/208 (28%), Positives = 77/208 (37%), Gaps = 30/208 (14%)
Query: 10 DLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLN--------- 60
+LE +L P PP +P R RA P E+ E E + A+ A+AA+
Sbjct: 20 ELEARQQLPPDPPAAP--PGRARAAPDEDREPESARMQRAQMAALAAMRAAAAGLGHPAS 77
Query: 61 -GGSGGG---------------GGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDE 104
GGS G G G G G GE S E E+E+ EED
Sbjct: 78 PGGSEDGPPGSEEEDAAREGTPGSPGRGREGPGEEHFEDMASDEDMKPKWEEEEMEEDLG 137
Query: 105 EEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKE---GLEEP 161
E+E+E EEE E +G G +S T A + GDG G +E
Sbjct: 138 EDEEEEEEDYEDEEEEEDEEGLGPPGPASLGTTALFPRKAQPPQAFRGDGVPRVLGGQER 197
Query: 162 KGPRGSQGGGGGGSSSSSVVSSGGDEGY 189
GP + GG + GD Y
Sbjct: 198 PGPGPAHPGGAAHVAPQLQPPDHGDWTY 225
Score = 33.9 bits (76), Expect = 0.37
Identities = 18/45 (40%), Positives = 26/45 (57%), Gaps = 10/45 (22%)
Query: 167 SQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSS 211
++GGGGGG SSS+ G GG++ TSGG+ G +S+
Sbjct: 548 NKGGGGGGGSSSN----------AGGRGGNTGTSGGQAGPAGLST 582
>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
Length = 663
Score = 60.1 bits (144), Expect = 5e-09
Identities = 28/89 (31%), Positives = 40/89 (44%)
Query: 268 CQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGDKP 327
C F + +L +H+ HV G VC W+ C P ++ L H+ H+G+KP
Sbjct: 431 CSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKP 490
Query: 328 FKCVVGGCNASFASQGGLARHVPTHFSQQ 356
F C GC FA L H TH ++
Sbjct: 491 FPCPFPGCGKVFARSENLKIHKRTHTGEK 519
Score = 50.1 bits (118), Expect = 5e-06
Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 12/98 (12%)
Query: 263 CCWDQCQA---CFNSSPDLADHIRSIHVDGQRGGVFVCLWKGC-KVYNTPSTSQSWLQRH 318
C W+ C F + L +HIR +H G++ F C + GC KV+ L+ H
Sbjct: 460 CFWEDCPREGKPFKAKYKLINHIR-VHT-GEKP--FPCPFPGCGKVFARSEN----LKIH 511
Query: 319 MLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQ 356
TH+G+KPFKC GC+ FA+ +H H S +
Sbjct: 512 KRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDK 549
Score = 42.0 bits (97), Expect = 0.001
Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 7/92 (7%)
Query: 261 YNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHML 320
+ C + C F S +L H R+ H G++ F C + GC + + S ++H
Sbjct: 491 FPCPFPGCGKVFARSENLKIHKRT-HT-GEKP--FKCEFDGC---DRKFANSSDRKKHSH 543
Query: 321 THSGDKPFKCVVGGCNASFASQGGLARHVPTH 352
H+ DKP+ C + GC+ S+ L +H+ H
Sbjct: 544 VHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIH 575
Score = 30.0 bits (66), Expect = 5.3
Identities = 38/178 (21%), Positives = 53/178 (29%), Gaps = 10/178 (5%)
Query: 18 SPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGG 77
+PL P A+ PP + E A A A A + G GGG G
Sbjct: 89 TPLGPEHMAQASTLGLSPPSQAFPAHPEAPAAAARAAALVAHPGAGSYPCGGGSSGAQPS 148
Query: 78 EAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDET 137
+ P P + S ++S GGG S G S D
Sbjct: 149 APPPPAPPLPPTPSPPPPPPPPPPPALSGYTTTNSGGGG----------SSGKGHSRDFV 198
Query: 138 RSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGG 195
A + ++ G E+ G Q S+ +S+ G G GG
Sbjct: 199 LRRDLSATAPAAAMHGAPLGGEQRSGTGSPQHPAPPPHSAGMFISASGTYAGPDGSGG 256
>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
Length = 532
Score = 59.3 bits (142), Expect = 8e-09
Identities = 28/89 (31%), Positives = 40/89 (44%)
Query: 268 CQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGDKP 327
C F++ +L H+ HV G VC W+ C P ++ L H+ H+G+KP
Sbjct: 273 CNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKP 332
Query: 328 FKCVVGGCNASFASQGGLARHVPTHFSQQ 356
F C GC FA L H TH ++
Sbjct: 333 FPCPFPGCGKVFARSENLKIHKRTHTGEK 361
Score = 53.5 bits (127), Expect = 4e-07
Identities = 34/105 (32%), Positives = 45/105 (42%), Gaps = 2/105 (1%)
Query: 101 EDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEE 160
E + + S ++ G E S+ LV S S +LSP AA++++ +
Sbjct: 416 ESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSS--NLSPAAAAAAAAAAAAAAAVSA 473
Query: 161 PKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRG 205
GS GG GG S S GG G G GGGGSS G G
Sbjct: 474 VHRGGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAG 518
Score = 50.1 bits (118), Expect = 5e-06
Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 12/98 (12%)
Query: 263 CCWDQCQA---CFNSSPDLADHIRSIHVDGQRGGVFVCLWKGC-KVYNTPSTSQSWLQRH 318
C W++C F + L +HIR +H G++ F C + GC KV+ L+ H
Sbjct: 302 CFWEECPREGKPFKAKYKLVNHIR-VHT-GEKP--FPCPFPGCGKVFARSEN----LKIH 353
Query: 319 MLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQ 356
TH+G+KPF+C GC+ FA+ +H+ H S +
Sbjct: 354 KRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDK 391
Score = 43.9 bits (102), Expect = 4e-04
Identities = 32/117 (27%), Positives = 55/117 (47%), Gaps = 9/117 (7%)
Query: 261 YNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHML 320
+ C + C F S +L H R+ H G++ F C ++GC S+ + ++HM
Sbjct: 333 FPCPFPGCGKVFARSENLKIHKRT-HT-GEKP--FQCEFEGCDRRFANSSDR---KKHMH 385
Query: 321 THSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSKVSSQPKAKEESPSKAGM 377
H+ DKP+ C + C+ S+ L +H+ H S S+ S + ES + G+
Sbjct: 386 VHTSDKPYLCKM--CDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGL 440
Score = 43.1 bits (100), Expect = 6e-04
Identities = 31/106 (29%), Positives = 45/106 (42%), Gaps = 5/106 (4%)
Query: 83 SEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSP 142
SE SP ++S E +SSS+ S A + ++ +++ ++
Sbjct: 422 SESSPAASSGYESSTPPGLVSPSAEPQSSSN-----LSPAAAAAAAAAAAAAAAVSAVHR 476
Query: 143 GAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEG 188
G S S G G G G G G GGGGGGSS ++GG G
Sbjct: 477 GGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSG 522
Score = 37.0 bits (84), Expect = 0.043
Identities = 30/116 (25%), Positives = 44/116 (37%), Gaps = 7/116 (6%)
Query: 76 GGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGS--SGGSS 133
G E+ + ES++ G E +++ ++A + V + GG S
Sbjct: 421 GSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGGGS 480
Query: 134 SDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGY 189
G S S G G G G G GS GGG G + S +SS +E Y
Sbjct: 481 GSGGAGGGSGGGSGSGGGGGGAGG-----GGGGSSGGGSGTAGGHSGLSSNFNEWY 531
Score = 36.2 bits (82), Expect = 0.074
Identities = 17/29 (58%), Positives = 19/29 (65%)
Query: 49 AEAEAVAALLLNGGSGGGGGGGGGGVGGG 77
A A AV+A+ GGSG GG GGG G G G
Sbjct: 466 AAAAAVSAVHRGGGSGSGGAGGGSGGGSG 494
Score = 35.0 bits (79), Expect = 0.16
Identities = 14/17 (82%), Positives = 14/17 (82%)
Query: 61 GGSGGGGGGGGGGVGGG 77
GGSG GGGGGG G GGG
Sbjct: 491 GGSGSGGGGGGAGGGGG 507
Score = 35.0 bits (79), Expect = 0.16
Identities = 14/22 (63%), Positives = 16/22 (72%)
Query: 60 NGGSGGGGGGGGGGVGGGEAET 81
+GG GGG GGGGGG GG + T
Sbjct: 495 SGGGGGGAGGGGGGSSGGGSGT 516
Score = 34.7 bits (78), Expect = 0.22
Identities = 29/93 (31%), Positives = 35/93 (37%), Gaps = 20/93 (21%)
Query: 18 SPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLN--------------GGS 63
S PPG +A EP A A A AA ++ GGS
Sbjct: 434 SSTPPGLVSPSA----EPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGGGSGSGGAGGGS 489
Query: 64 GGG--GGGGGGGVGGGEAETMSEPSPESASQAG 94
GGG GGGGGG GGG + S + +G
Sbjct: 490 GGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSG 522
>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
Length = 398
Score = 59.3 bits (142), Expect = 8e-09
Identities = 44/154 (28%), Positives = 58/154 (37%), Gaps = 25/154 (16%)
Query: 62 GSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESS 121
GSGGG GGG G S +S +G + D S SS GG S
Sbjct: 236 GSGGGSSNSGGGSG----------SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGS 285
Query: 122 AESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVV 181
+ G+SGGS D S G+++ SS G+ GG GGG+
Sbjct: 286 SGGSSGNSGGSRGDSGSESSWGSSTGSSS---------------GNHGGSGGGNGHKPGC 330
Query: 182 SSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEP 215
G+E G+G G G S +S+ P
Sbjct: 331 EKPGNEARGSGESGIQGFRGQGVSSNMRNSETSP 364
Score = 56.6 bits (135), Expect = 5e-08
Identities = 46/148 (31%), Positives = 60/148 (40%), Gaps = 19/148 (12%)
Query: 62 GSGGGGGGGGG--GVGGGEAETMSEPSPESASQAGEDED-EEEDDEEEEDESSSSGGGEE 118
G+ G GG GG G +++P S + ++E SS+SGGG
Sbjct: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
Query: 119 ESSAESLVGSSG-GSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSS 177
S GSSG GS+ D S G +SS S G G G GG G+S
Sbjct: 250 SQS-----GSSGSGSNGDNNNGSSSGGSSSGSSSG----------GSSGGSSGGSSGNSG 294
Query: 178 SSVVSSGGDEGYGTGGGGSSATSGGRRG 205
S SG + +G+ G SS GG G
Sbjct: 295 GSRGDSGSESSWGSSTGSSSGNHGGSGG 322
Score = 56.2 bits (134), Expect = 7e-08
Identities = 53/177 (29%), Positives = 69/177 (38%), Gaps = 23/177 (12%)
Query: 64 GGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAE 123
G GG GG G +++P S + ++E SS+ GG S +
Sbjct: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQS- 252
Query: 124 SLVGSSG-GSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSS----- 177
GSSG GS+ D S G +SS S G G G G+ GG G S S
Sbjct: 253 ---GSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGG--SSGGSSGNSGGSRGDSGSESSWG 307
Query: 178 SSVVSSGGDEGYGTGGG----------GSSATSGGRRGSLEMSSDGEPLSRMDSEDS 224
SS SS G+ G G+GGG G+ A G G G + +SE S
Sbjct: 308 SSTGSSSGNHG-GSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETS 363
Score = 52.8 bits (125), Expect = 8e-07
Identities = 45/155 (29%), Positives = 61/155 (39%), Gaps = 18/155 (11%)
Query: 61 GGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEES 120
G GG GG G G GG + SA G + + + G + +
Sbjct: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211
Query: 121 SAESLVGSSGGSSSDETRSLSP----GAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSS 176
A+ GS S+ +E + P G SS+SG G G + GS G G G +
Sbjct: 212 VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQS--------GSSGSGSNGDN 263
Query: 177 SSSVVSSGGDEGYGTGG------GGSSATSGGRRG 205
++ S G G +GG GGSS SGG RG
Sbjct: 264 NNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
Score = 38.5 bits (88), Expect = 0.015
Identities = 42/167 (25%), Positives = 61/167 (36%), Gaps = 27/167 (16%)
Query: 115 GGEEESSAESLVGSSGGSSSDETRSLSPGAASSS-----SGDGDGKEGLEEPKGPRGSQG 169
G E S + GS GG + PG + G+ G G+ P G G
Sbjct: 140 GAWETSGGHGIFGSQGGLGGQGQGN--PGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGG 197
Query: 170 GGGGGSSSSSVVSSGGDEGYGT-----------------GGGGSSATSGG---RRGSLEM 209
GG + ++ + GYG+ GGGSS + GG + GS
Sbjct: 198 NGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS 257
Query: 210 SSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSS 256
S+G+ + S S S + S SSG S+ +G + S S
Sbjct: 258 GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES 304
Score = 38.1 bits (87), Expect = 0.019
Identities = 39/128 (30%), Positives = 44/128 (34%), Gaps = 45/128 (35%)
Query: 60 NGGSGGGGGGG---GGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGG 116
NG S GG G GG GG S +SGG
Sbjct: 265 NGSSSGGSSSGSSSGGSSGGSSG----------------------------GSSGNSGGS 296
Query: 117 EEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEP------KGPRGSQGG 170
+S +ES GSS GSSS G S G K G E+P G G QG
Sbjct: 297 RGDSGSESSWGSSTGSSS--------GNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGF 348
Query: 171 GGGGSSSS 178
G G SS+
Sbjct: 349 RGQGVSSN 356
Score = 30.0 bits (66), Expect = 5.3
Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 14/105 (13%)
Query: 134 SDETRSLSPGAASSSSGDGDGK-----EGLEEPKGPR-GSQGGGGGGSSSSSVVSSGGDE 187
S E L G S+ + G+ + L E G G + GG GS S + G E
Sbjct: 18 SGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTRE 77
Query: 188 GYGTG-----GGGSSATSGGRRGSL--EMSSDGEPLSRMDSEDSI 225
GTG G G++ G R G + + G + R +ED I
Sbjct: 78 AVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVI 121
>gi|22547201 zinc finger protein of the cerebellum 4 [Homo sapiens]
Length = 334
Score = 59.3 bits (142), Expect = 8e-09
Identities = 27/89 (30%), Positives = 40/89 (44%)
Query: 268 CQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGDKP 327
C F++ +L H+ HV G +C W+ C P ++ L H+ H+G+KP
Sbjct: 144 CSKTFSTMHELVTHVTVEHVGGPEQANHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKP 203
Query: 328 FKCVVGGCNASFASQGGLARHVPTHFSQQ 356
F C GC FA L H TH ++
Sbjct: 204 FPCPFPGCGKVFARSENLKIHKRTHTGEK 232
Score = 49.7 bits (117), Expect = 6e-06
Identities = 43/149 (28%), Positives = 66/149 (44%), Gaps = 20/149 (13%)
Query: 263 CCWDQCQAC---FNSSPDLADHIRSIHVDGQRGGVFVCLWKGC-KVYNTPSTSQSWLQRH 318
C W++C F + L +HIR +H G++ F C + GC KV+ L+ H
Sbjct: 173 CFWEECPRQGKPFKAKYKLVNHIR-VHT-GEKP--FPCPFPGCGKVFARSEN----LKIH 224
Query: 319 MLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQ-NSSKVSSQPKAKEESPSKAGM 377
TH+G+KPF+C GC FA+ +H H S + + KV K S +
Sbjct: 225 KRTHTGEKPFRCEFEGCERRFANSSDRKKHSHVHTSDKPYTCKVRGCDKCYTHPSS---L 281
Query: 378 NKRRKLKNKRRRSLPRPHDFFDAQTLDAI 406
K K+ + P P +D+ T A+
Sbjct: 282 RKHMKVHGRS----PPPSSGYDSATPSAL 306
>gi|167466187 integrin-binding sialoprotein precursor [Homo sapiens]
Length = 317
Score = 58.9 bits (141), Expect = 1e-08
Identities = 49/182 (26%), Positives = 76/182 (41%), Gaps = 24/182 (13%)
Query: 23 GSPGSAARGRAEPPEEEEEEEE------------EEEEAEAEAVAALLLNGGSGGGGGGG 70
GS S+ + EEEEEEEE E+E++EAE G G G
Sbjct: 62 GSSDSSEENGDDSSEEEEEEEETSNEGENNEESNEDEDSEAENTTLSATTLGYGEDATPG 121
Query: 71 GGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSG 130
G G + + + E E +EE++EEEE + E + + + + G+S
Sbjct: 122 TGYTGLAAIQLPKKAGDITNKATKEKESDEEEEEEEEGNENEESEAEVDENEQGINGTST 181
Query: 131 GSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQ-----GGGGGGSSSSSVVSSGG 185
S+ E + SSG +G+EG EE ++ G G G+S ++ +GG
Sbjct: 182 NSTEAEN-------GNGSSGGDNGEEGEEESVTGANAEDTTETGRQGKGTSKTTTSPNGG 234
Query: 186 DE 187
E
Sbjct: 235 FE 236
Score = 39.7 bits (91), Expect = 0.007
Identities = 36/139 (25%), Positives = 55/139 (39%), Gaps = 11/139 (7%)
Query: 19 PLPPGSPGSAARGRAEPPEEEEEEEE--EEEEAEAEAVAALLLNGGSGGGGGGGGGGVGG 76
P G + A E EEEEEEEE E EE+EAE G G
Sbjct: 133 PKKAGDITNKATKEKESDEEEEEEEEGNENEESEAEV---------DENEQGINGTSTNS 183
Query: 77 GEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDE 136
EAE + S + GE+E + E+ E+ G G +++ G +
Sbjct: 184 TEAENGNGSSGGDNGEEGEEESVTGANAEDTTETGRQGKGTSKTTTSPNGGFEPTTPPQV 243
Query: 137 TRSLSPGAASSSSGDGDGK 155
R+ SP +++ + +G+
Sbjct: 244 YRTTSPPFGKTTTVEYEGE 262
Score = 38.5 bits (88), Expect = 0.015
Identities = 41/185 (22%), Positives = 73/185 (39%), Gaps = 27/185 (14%)
Query: 85 PSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAE--------SLVGSSGGSSSDE 136
P S+ + E+ D+ ++EEEE+E+S+ G EES+ + +L ++ G D
Sbjct: 59 PVQGSSDSSEENGDDSSEEEEEEEETSNEGENNEESNEDEDSEAENTTLSATTLGYGEDA 118
Query: 137 T-----RSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGY-G 190
T L+ +GD K E+ + G + S ++G G
Sbjct: 119 TPGTGYTGLAAIQLPKKAGDITNKATKEKESDEEEEEEEEGNENEESEAEVDENEQGING 178
Query: 191 TGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQG 250
T + A +G + +GE E+S++ + + T +GR G
Sbjct: 179 TSTNSTEAENGNGSSGGDNGEEGE-------EESVTGA--NAEDTTETGRQG----KGTS 225
Query: 251 STTSS 255
TT+S
Sbjct: 226 KTTTS 230
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.127 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,338,375
Number of Sequences: 37866
Number of extensions: 1468096
Number of successful extensions: 67767
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1777
Number of HSP's successfully gapped in prelim test: 1438
Number of HSP's that attempted gapping in prelim test: 15778
Number of HSP's gapped (non-prelim): 25690
length of query: 517
length of database: 18,247,518
effective HSP length: 107
effective length of query: 410
effective length of database: 14,195,856
effective search space: 5820300960
effective search space used: 5820300960
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.