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Search of human proteins with 166295204
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|166295204 hypothetical protein LOC80127 [Homo sapiens]
(529 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|166295204 hypothetical protein LOC80127 [Homo sapiens] 1034 0.0
gi|71061468 centromere protein E [Homo sapiens] 74 3e-13
gi|55770834 centromere protein F [Homo sapiens] 74 4e-13
gi|118498362 kinectin 1 isoform b [Homo sapiens] 72 1e-12
gi|118498356 kinectin 1 isoform a [Homo sapiens] 72 1e-12
gi|118498368 kinectin 1 isoform c [Homo sapiens] 72 1e-12
gi|33620775 kinectin 1 isoform a [Homo sapiens] 72 1e-12
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 72 1e-12
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 72 1e-12
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 72 1e-12
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 72 1e-12
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 72 1e-12
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 72 1e-12
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 72 2e-12
gi|221219020 NYD-SP11 protein [Homo sapiens] 71 3e-12
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 70 4e-12
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 70 5e-12
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 70 6e-12
gi|118918423 hypothetical protein LOC286207 [Homo sapiens] 69 8e-12
gi|21735548 centrosomal protein 2 [Homo sapiens] 67 5e-11
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 66 9e-11
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 65 2e-10
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 65 2e-10
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 65 2e-10
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 65 2e-10
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 65 2e-10
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 65 2e-10
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 65 2e-10
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 65 2e-10
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 65 2e-10
>gi|166295204 hypothetical protein LOC80127 [Homo sapiens]
Length = 529
Score = 1034 bits (2674), Expect = 0.0
Identities = 529/529 (100%), Positives = 529/529 (100%)
Query: 1 MPSKGKDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRIL 60
MPSKGKDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRIL
Sbjct: 1 MPSKGKDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRIL 60
Query: 61 AKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQK 120
AKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQK
Sbjct: 61 AKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQK 120
Query: 121 YTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQET 180
YTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQET
Sbjct: 121 YTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQET 180
Query: 181 LRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHL 240
LRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHL
Sbjct: 181 LRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHL 240
Query: 241 KETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALS 300
KETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALS
Sbjct: 241 KETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALS 300
Query: 301 YMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVE 360
YMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVE
Sbjct: 301 YMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVE 360
Query: 361 RFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAACTGRTEYPKIRTFDGREHSTNSVN 420
RFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAACTGRTEYPKIRTFDGREHSTNSVN
Sbjct: 361 RFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAACTGRTEYPKIRTFDGREHSTNSVN 420
Query: 421 QDLLEAEKWTHIEGNVDIGDLTWEQKEKVLRLLFAKMNGCPSRKYNQSSRPPVPDYVVSD 480
QDLLEAEKWTHIEGNVDIGDLTWEQKEKVLRLLFAKMNGCPSRKYNQSSRPPVPDYVVSD
Sbjct: 421 QDLLEAEKWTHIEGNVDIGDLTWEQKEKVLRLLFAKMNGCPSRKYNQSSRPPVPDYVVSD 480
Query: 481 SGETKEFGDESKLQDKIFITQQIAISDSSGEVVLPTIPKEPQESDTGTF 529
SGETKEFGDESKLQDKIFITQQIAISDSSGEVVLPTIPKEPQESDTGTF
Sbjct: 481 SGETKEFGDESKLQDKIFITQQIAISDSSGEVVLPTIPKEPQESDTGTF 529
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 73.9 bits (180), Expect = 3e-13
Identities = 103/495 (20%), Positives = 205/495 (41%), Gaps = 103/495 (20%)
Query: 3 SKGKDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRI--KYRDTSRIL 60
SK + K K +T K++ E + +++L +E+ LS+ + D + +
Sbjct: 1384 SKQEQSLNMKEKDNETTKIVSEMEQFKPK---DSALLRIEIEMLGLSKRLQESHDEMKSV 1440
Query: 61 AKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQK 120
AK +DL++ Q ++ + DQ K+N+ E + + L +E EQ+
Sbjct: 1441 AKEKDDLQRLQEVLQSE----------SDQLKENIKEIVAKHLETEEELKVAHCCLKEQE 1490
Query: 121 YTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQ----------------VERELD 164
T INEL +K EI I +L+A+ + KIQ V+ +++
Sbjct: 1491 ET--INELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVN 1548
Query: 165 DLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRN 224
+LK+ + + L+ +ES+ E +RL++ E+ IM+ E+ + + + R+
Sbjct: 1549 ELKQ-FKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERD 1607
Query: 225 VFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQ 284
KEN KE A K S QE L +N+ +EK+ ++ + Q
Sbjct: 1608 QLKEN----------TKEIVAKMKES---QEKEYQFLKMTAVNE--TQEKMCEIEHLKEQ 1652
Query: 285 IQTLQKKVVNLET--------------ALSYMTKEFE-----SEVLKLQQHAMIENQAGQ 325
+T + + N+ET + +TKE + E LK+++ + EN
Sbjct: 1653 FETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRET 1712
Query: 326 V--EIDKLQHL----LQMKDREMNRVKKLAKNILDERTEVERFFLDALH----------Q 369
+ +++K + L + +K+ + + KL + ++ E+ D H +
Sbjct: 1713 ITRDLEKQEELKIVHMHLKEHQ-ETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLK 1771
Query: 370 VKQQILISRKHYKQIAQAAFNLKMRAACTGRTE----------------YPKIRTFDGRE 413
+++++ I+ H K+ Q K+R + +T+ KI+ E
Sbjct: 1772 IQEELRIAHMHLKE--QQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANE 1829
Query: 414 HSTNSVNQDLLEAEK 428
H ++ +D+ E +K
Sbjct: 1830 HQLITLKKDVNETQK 1844
Score = 62.4 bits (150), Expect = 1e-09
Identities = 88/410 (21%), Positives = 179/410 (43%), Gaps = 47/410 (11%)
Query: 7 DKKKG--KSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSN 64
DK +G K + + K E D KA + L + + + ++T L
Sbjct: 1738 DKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIV 1797
Query: 65 EDLKKKQCKMEKDIMSVLSYLKKQDQE---KDNMIEKLKQQLNETKEKAQE----EKDKL 117
+ K M+KD+ + + L+++ QE ++ + LK+ +NET++K E +K
Sbjct: 1798 SEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIK 1857
Query: 118 EQKYTRQINELEG-----QFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRN 172
+Q T E+E + H+ +E+ + E +R+ ++ ++ E D LKE+L+
Sbjct: 1858 DQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEET---LKLERDQLKESLQE 1914
Query: 173 TERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYL 232
T+ E + L++ L +E ++ + L E+ E +Q++D +++ K D L
Sbjct: 1915 TKARDLEIQQELKTA-----RMLSKEHKETVDKLREKIS-EKTIQISDIQKDLDKSKDEL 1968
Query: 233 QKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKV 292
QK + K+ L + + + SH + +++ + + + Q +K
Sbjct: 1969 QKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLH 2028
Query: 293 VNLETALSYMTKEFE-----SEVLKLQQHAMI---------ENQAGQVEIDK------LQ 332
+LE + + KE + E LK+++ I + Q QV+ +K Q
Sbjct: 2029 ESLE-EIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQ 2087
Query: 333 HLLQMKDREMNRVKKLAKNI--LDERTE-VERFFLDALHQVKQQILISRK 379
HL + + +R+K+L K +D+ E + R LD +++ Q +S +
Sbjct: 2088 HLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMR 2137
Score = 53.5 bits (127), Expect = 5e-07
Identities = 76/350 (21%), Positives = 146/350 (41%), Gaps = 65/350 (18%)
Query: 33 KANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEK 92
K ++SL + E++ ++ T + + NE + K+ +D S L+ ++EK
Sbjct: 856 KFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRD-----STLQTVEREK 910
Query: 93 DNMIEKLKQQLNETKEKAQEEKD--KLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVR 150
+ EKL+Q L E K QE+ D +L++ + ++L+ H
Sbjct: 911 TLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTV-------------- 956
Query: 151 QFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERA 210
I + +L + E+L+ HQET+ L+S+ EE ++
Sbjct: 957 ---NMNIDTQEQLRNALESLKQ----HQETINTLKSKISEE--------------VSRNL 995
Query: 211 HHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLL 270
H E N + D Q+ + K+ D KN+Q TL K+ +
Sbjct: 996 HME---------ENTGETKDEFQQKMVGIDKKQDLEAKNTQ------TLTADVKDNEIIE 1040
Query: 271 VKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDK 330
+ KI L+Q+++++Q + + V+ + L KE ++ Q+ + E+ K
Sbjct: 1041 QQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGD----ELKK 1096
Query: 331 LQHLL-QMKDREMNRVKKLAKNILDERTEVERFFLDALHQV--KQQILIS 377
Q ++ Q K+ + + +L++ D EVE + Q+ KQQ L++
Sbjct: 1097 QQEIVAQEKNHAIKKEGELSRT-CDRLAEVEEKLKEKSQQLQEKQQQLLN 1145
Score = 52.4 bits (124), Expect = 1e-06
Identities = 117/558 (20%), Positives = 226/558 (40%), Gaps = 81/558 (14%)
Query: 6 KDKKKGKSKGKDTKKL--IKTD-----ESVVDRAKANASLWEARLEVTELSRIKYRDTSR 58
+D+ K + D++KL IK D ES+ D + +L++A + R S
Sbjct: 588 EDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKR-----ESA 642
Query: 59 ILAKSNEDLKKKQCK-------MEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQ 111
L N +LK+K + ME DI S L+ + + + ++ ++L+ NE +
Sbjct: 643 FLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTS 702
Query: 112 EEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLR 171
K+ + + ELEG+ KE+ E +A+R+ ++ + EL L +
Sbjct: 703 LIDGKVPKDLLCNL-ELEGKITDLQKELNKEVEENEALRE----EVILLSELKSLPSEV- 756
Query: 172 NTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQ--LNDAGRNV---- 225
E LR+ EE H + E +K + +E H E+ VQ L + G+
Sbjct: 757 -------ERLRKEIQDKSEELHIITSEKDK---LFSEVVHKESRVQGLLEEIGKTKDDLA 806
Query: 226 -----FKENDY-LQKALAYHL-----------------KETDALQKNSQKLQESHTLLLH 262
+K D Q H+ +E L K +QK S L
Sbjct: 807 TTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKT 866
Query: 263 QKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQ 322
+ ++EK ++ ++ ++++ L++++ N ++ L + +E KLQQ + E +
Sbjct: 867 ELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQ-TLEEVK 925
Query: 323 AGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQVKQ-QILISRKHY 381
E D L+ L + E +++K + ++ + + +AL +KQ Q I+
Sbjct: 926 TLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKS 985
Query: 382 KQIAQAAFNLKMRAACTGRTEYPKIRTFDGREHSTNSVNQDLLEAEKWTHIEGNVDIGDL 441
K + + NL M TG T+ + G + + LEA+ + +V ++
Sbjct: 986 KISEEVSRNLHMEEN-TGETKDEFQQKMVGIDKKQD------LEAKNTQTLTADVKDNEI 1038
Query: 442 TWEQKEKVLRLLFAK-------MNGCPSRKYNQSSRPPVPDYVVSDSGETKEFGDESKLQ 494
EQ+ K+ L+ K + ++ ++ + + + E + GDE K Q
Sbjct: 1039 I-EQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQ 1097
Query: 495 DKIFITQQIAISDSSGEV 512
+I ++ GE+
Sbjct: 1098 QEIVAQEKNHAIKKEGEL 1115
Score = 50.1 bits (118), Expect = 5e-06
Identities = 72/331 (21%), Positives = 144/331 (43%), Gaps = 54/331 (16%)
Query: 19 KKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDI 78
K+ +KTD K N + E L + + I+A+ KK+ ++ +
Sbjct: 1066 KEQLKTD------LKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTC 1119
Query: 79 MSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQ-KAK 137
L+ ++++ +EK +++ +QQL +E+ E + K INE+E ++ K K
Sbjct: 1120 -DRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKK--------INEIENLKNELKNK 1170
Query: 138 EIGMIHTELKAVRQFQK--------RKIQVERELDDLKENLRNTERIH-QETLRRLESRF 188
E+ + H E + + QK + I ER++ + TER H + +R +E+
Sbjct: 1171 ELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATG 1230
Query: 189 FEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQK 248
+ K L KI + + H E I +L + + E A
Sbjct: 1231 LQTKEEL------KIAHIHLKEHQETIDELRRS------------------VSEKTAQII 1266
Query: 249 NSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFES 308
N+Q L++SHT L Q+EI L +++++ V++ S+ Q + LE T + +
Sbjct: 1267 NTQDLEKSHTKL--QEEIPVLHEEQELLPNVKEVSETQETMNE---LELLTEQSTTKDST 1321
Query: 309 EVLKLQQHAMIENQAGQVEIDKLQHLLQMKD 339
+ +++ + N+ Q ++++ L + +D
Sbjct: 1322 TLARIEMERLRLNEKFQESQEEIKSLTKERD 1352
Score = 46.6 bits (109), Expect = 6e-05
Identities = 87/457 (19%), Positives = 186/457 (40%), Gaps = 97/457 (21%)
Query: 6 KDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNE 65
+D +K +K ++ ++ ++ ++ K + E E+ L+ S LA+
Sbjct: 1269 QDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLAR--- 1325
Query: 66 DLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQ------ 119
++ ++ ++ + +K +E+DN L KE + + D+L++
Sbjct: 1326 -IEMERLRLNEKFQESQEEIKSLTKERDN--------LKTIKEALEVKHDQLKEHIRETL 1376
Query: 120 ---------------------KYTRQINELEGQFHQK--------------AKEIGMIHT 144
+ T+ ++E+E QF K +K + H
Sbjct: 1377 AKIQESQSKQEQSLNMKEKDNETTKIVSEME-QFKPKDSALLRIEIEMLGLSKRLQESHD 1435
Query: 145 ELKAVRQ----FQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAE 200
E+K+V + Q+ + ++ E D LKEN++ H ET L+ K + E+
Sbjct: 1436 EMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQ-EETIN 1494
Query: 201 KKIIMLAERAHHEAIVQ-----LNDAGRNVFKENDYLQKALAYHLKETDALQK------- 248
+ + L+E+ + +Q +ND +N K + +K +++K+ +Q+
Sbjct: 1495 ELRVNLSEKETEISTIQKQLEAINDKLQN--KIQEIYEKEEQFNIKQISEVQEKVNELKQ 1552
Query: 249 ---------------NSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVV 293
S+ L+ ++ L Q+EI ++ +++ M+ VQ+ QI+ Q K
Sbjct: 1553 FKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLK-E 1611
Query: 294 NLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMK-------DREMNRVK 346
N + ++ M + E E L+ A+ E Q EI+ L+ + + + E R+
Sbjct: 1612 NTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLT 1671
Query: 347 KLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQ 383
++ L+E V + D L V++ + + R K+
Sbjct: 1672 QILHENLEEMRSVTK-ERDDLRSVEETLKVERDQLKE 1707
Score = 45.4 bits (106), Expect = 1e-04
Identities = 71/360 (19%), Positives = 161/360 (44%), Gaps = 30/360 (8%)
Query: 48 LSRIKYRDTSRILAKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETK 107
LS I++ +++L + N + + + + D + VL Y ++ EK+ M KLK++ + +
Sbjct: 479 LSEIEWNPATKLLNQENIESELNSLRADYDNL-VLDY-EQLRTEKEEMELKLKEKNDLDE 536
Query: 108 EKAQEEKDKLEQ--KYTRQINELEG------QFHQKAKEIGMIHTELKAVRQFQKRKIQV 159
+A E K K +Q + +I+ L+ ++Q + EL ++ Q +K+Q
Sbjct: 537 FEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQE 596
Query: 160 ---ERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIV 216
++L+++K +L + ++ + ++ F E L+ + E + E +
Sbjct: 597 YIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMK 656
Query: 217 QLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIM 276
+L + + + Q L K L+K +LQ + + + D V + ++
Sbjct: 657 ELATTYKQMENDIQLYQSQLEAKKKMQVDLEK---ELQSAFNEITKLTSLIDGKVPKDLL 713
Query: 277 QLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQ 336
++ +I LQK+ +N E E+E L+ + + E ++ E+++L+ +Q
Sbjct: 714 CNLELEGKITDLQKE-LNKEVE--------ENEALREEVILLSELKSLPSEVERLRKEIQ 764
Query: 337 MKDREMNRV----KKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAAFNLK 392
K E++ + KL ++ + + V+ L+ + + K + ++ +YK Q N K
Sbjct: 765 DKSEELHIITSEKDKLFSEVVHKESRVQG-LLEEIGKTKDDLATTQSNYKSTDQEFQNFK 823
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 73.6 bits (179), Expect = 4e-13
Identities = 83/323 (25%), Positives = 144/323 (44%), Gaps = 40/323 (12%)
Query: 61 AKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQ- 119
A+ ++L++ + M + + L L Q+ +N +E+ KQ+L ++ Q + K +
Sbjct: 419 ARLTQELQQAK-NMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENEL 477
Query: 120 -----KYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTE 174
+ ++ N L+ QKA+E+ + ELK ++Q + E+ +
Sbjct: 478 RRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETML 537
Query: 175 RIHQETLRRLESRFFEEKHR-----LEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKEN 229
R QE + + E+ EK + LE++ + +L +R HH I QLND KE+
Sbjct: 538 RDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHH--IEQLNDKLSKTEKES 595
Query: 230 DYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQ 289
L AL + +K ++L+E TL K N+ L L Q S+ + LQ
Sbjct: 596 KALLSAL-------ELKKKEYEELKEEKTLFSCWKSENEKL-------LTQMESEKENLQ 641
Query: 290 KKVVNLETAL---SYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVK 346
K+ +LET L + E+ V L+ ++ + VEI L ++L K E+ +
Sbjct: 642 SKINHLETCLKTQQIKSHEYNERVRTLE----MDRENLSVEIRNLHNVLDSKSVEV-ETQ 696
Query: 347 KLAKNILDERTEVERFFLDALHQ 369
KLA L ++ E F D HQ
Sbjct: 697 KLAYMELQQKAE----FSDQKHQ 715
Score = 52.0 bits (123), Expect = 1e-06
Identities = 79/338 (23%), Positives = 132/338 (39%), Gaps = 79/338 (23%)
Query: 94 NMIEKLKQQLNETKEKAQ--EEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQ 151
N+ ++K+ NE E++D+ + ++ EL+ + H + ++ T+++A +
Sbjct: 1771 NLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQL---MTKIEACIE 1827
Query: 152 FQKRKIQVERELDDLKENLRNTERIHQETLRRLE-------------------------- 185
+K ++++E DL E L HQE L+R+E
Sbjct: 1828 LEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVA 1887
Query: 186 -----------------SRFFEEKHRLEQEA------------EKKIIMLAERAHHEAIV 216
SR EK +E EA EK + + IV
Sbjct: 1888 KVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIV 1947
Query: 217 QLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQ------ESH-TLLLHQKEINDL 269
L + V E + L+ L K+T AL + S+K++ ESH + LH ++ +
Sbjct: 1948 CLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEA 2007
Query: 270 LVKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQV--- 326
VKEK L S + L K +L+ L + K +S+ L L + +ENQ Q+
Sbjct: 2008 EVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEK--DSQALSLTK-CELENQIAQLNKE 2064
Query: 327 ------EIDKLQHLLQMKDREMNRVKKLAKNILDERTE 358
E + LQ L D E V K + L E+ E
Sbjct: 2065 KELLVKESESLQARLSESDYEKLNVSKALEAALVEKGE 2102
Score = 50.8 bits (120), Expect = 3e-06
Identities = 69/344 (20%), Positives = 131/344 (38%), Gaps = 65/344 (18%)
Query: 60 LAKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEK----- 114
L + E L + + +++ L LKK+ Q++ ++ L+ L + K+K + EK
Sbjct: 5 LEEWKEGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTN 64
Query: 115 ---------------DKLEQKYTR-------QINELEGQFHQKAKEIGMIHTELKAVRQF 152
+K +QK + Q+N EGQ + K+I + ELK +
Sbjct: 65 LKRENQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSE 124
Query: 153 QKRKIQVERELDDLKENLRNTERI--------------HQETLRRLESRFFEEKHRLEQE 198
+R Q + D ++I E L+ ++ EE+ RLE E
Sbjct: 125 LERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKRLEAE 184
Query: 199 AEKKIIMLAERAHHEAIVQLNDAGRNVFKEN--DYLQKALAYHLKETDALQKNSQKLQES 256
+ A + +A + D R+ + + Q+ HL + S
Sbjct: 185 VKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSAS 244
Query: 257 H------------TLLLHQKEINDLLVKEKIMQ--LVQQRSQIQTLQKKVVNLETALSYM 302
+ TL + +++ N L Q ++Q Q L+ K+ LE L
Sbjct: 245 YFSGEQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGH 304
Query: 303 TKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVK 346
KE + +V K Q+ Q++++K + L K++ +N+ +
Sbjct: 305 EKEMKGQVNKFQEL--------QLQLEKAKVELIEKEKVLNKCR 340
Score = 49.7 bits (117), Expect = 7e-06
Identities = 78/449 (17%), Positives = 175/449 (38%), Gaps = 69/449 (15%)
Query: 7 DKKKGKSKGKDTKKL-----IKTDESVVDRAKANASLWEARLEVTE-------LSRIKYR 54
+K + + + + K+L +K E D K E LE+ L +
Sbjct: 2304 EKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSK 2363
Query: 55 DTSRILAKSNEDLKKKQCKMEKDIMSVLSYLK------KQDQEKDNMIEKLKQQLNETKE 108
L E + + +E D++++ S + +++QE+ + +E + +
Sbjct: 2364 GEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQ 2423
Query: 109 KAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKE 168
+ ++EK ++++K + + L+ Q + + + +H + +A + ++ +L
Sbjct: 2424 EKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQ----------NLSS 2473
Query: 169 NLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKE 228
+ E + L+ L+ EA+ I+L + ++Q + G+ ++
Sbjct: 2474 QVECLELEKAQLLQGLD------------EAKNNYIVLQSSVN--GLIQEVEDGKQKLEK 2519
Query: 229 NDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQK-EINDLLVKEKIMQLVQQRSQIQT 287
D L +++ + L +++ H L Q E+ +L V+ +IQ
Sbjct: 2520 KDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNL--------TVELEQKIQV 2571
Query: 288 LQKKVVNLETAL-----SYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREM 342
LQ K +L+ L SY E E E+ K+ + + +E +++K+ REM
Sbjct: 2572 LQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVE------KVNKMTAKETELQREM 2625
Query: 343 NRVKKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAACTGRTE 402
+ + + + +E + + L + ++I S+ K++ LK C + +
Sbjct: 2626 HEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQ 2685
Query: 403 YPK-------IRTFDGREHSTNSVNQDLL 424
K I + R H +Q LL
Sbjct: 2686 VEKEGKVREEIAEYQLRLHEAEKKHQALL 2714
Score = 47.0 bits (110), Expect = 4e-05
Identities = 105/527 (19%), Positives = 207/527 (39%), Gaps = 78/527 (14%)
Query: 40 EARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEK- 98
EA LEV + ++ L K NE+ +K +E+++ V S + E D M +K
Sbjct: 1922 EADLEVVQTEKL-------CLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKT 1974
Query: 99 --LKQQLNETKEKAQE--------------------EKDKLEQKYTRQINEL-EGQFHQK 135
L Q + KEK QE EK +L Q + ++EL + + H +
Sbjct: 1975 TALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQ 2034
Query: 136 AK---------EIGMIHTELK-AVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLE 185
K + + EL+ + Q K K + +E + L+ L ++ + LE
Sbjct: 2035 EKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALE 2094
Query: 186 SRFFE-------------EKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYL 232
+ E E H+L + EK + + A + + + + + +END L
Sbjct: 2095 AALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRI--EADEKKQLHIAEKLKERERENDSL 2152
Query: 233 QKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKV 292
+ + + L++ Q +E+ L++ E + V+ Q+ + ++ + +
Sbjct: 2153 KD-------KVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDL 2205
Query: 293 VNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNI 352
V L + +TK+ + + +L + + + + +K Q +Q+K+ V+ L +
Sbjct: 2206 VTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQL 2265
Query: 353 LDERTEVERFFLD-ALHQVKQQIL---ISRKHYKQIAQAAFNLKMRAACTGRTEYPKIRT 408
+ V D + + +Q L I +H Q+ + L+ R + + ++
Sbjct: 2266 KELNEAVAALCGDQEIMKATEQSLDPPIEEEH--QLRNSIEKLRARLEADEKKQLCVLQQ 2323
Query: 409 FDGREHSTNSVNQDLLEAEKWTHI-EGNVDIGDLTWEQKEKVLRLLFAKMNGCPSRKYNQ 467
EH + + + E+ I N + L E + + L AK+ G Q
Sbjct: 2324 LKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEG-----MTQ 2378
Query: 468 SSRPPVPDYVVSDSGETKEFGDESKLQDKIFITQQIAISDSSGEVVL 514
S R D V S + + K Q++I ++ I +SS E +L
Sbjct: 2379 SLRGLELDVVTIRSEKENLTNELQKEQERI---SELEIINSSFENIL 2422
Score = 47.0 bits (110), Expect = 4e-05
Identities = 78/377 (20%), Positives = 162/377 (42%), Gaps = 40/377 (10%)
Query: 23 KTDESVVDRAKANASLWEARLEVTELSR---IKYRDTSRILAKSNEDLKKKQC-KMEKDI 78
K E V + K++ ++ + ++ EL+ + D AK + +C ++EK
Sbjct: 2425 KEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEK-- 2482
Query: 79 MSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKE 138
L+ D+ K+N I L+ +N ++ ++ K KLE+K +I+ L+ Q + +
Sbjct: 2483 ---AQLLQGLDEAKNNYIV-LQSSVNGLIQEVEDGKQKLEKK-DEEISRLKNQIQDQEQL 2537
Query: 139 IGMIHT-----ELKAVRQFQKRKIQVERE-----LDDLKENLRNTERIHQETLRRLESRF 188
+ + +L + + R + VE E L +L++T + Q + + LE+
Sbjct: 2538 VSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENEL 2597
Query: 189 FEEKHRLEQEAEKKIIMLA-----ERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKET 243
K EK M A +R HE + + + E + L L L+E
Sbjct: 2598 ELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEI 2657
Query: 244 DALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLE----TAL 299
+ + ++L ++ L K+ D + K+++ + + R +I Q ++ E L
Sbjct: 2658 KSSKDQLKELTLENSEL---KKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALL 2714
Query: 300 SYMTKEFESEVLKLQQHAMIENQ---AGQVEIDKLQHLLQMKDREMNRVKKLAKNILDER 356
K++E E+ ++ + + + ++EID LL+ E+N K IL+E
Sbjct: 2715 LDTNKQYEVEIQTYREKLTSKEECLSSQKLEID----LLKSSKEELNNSLKATTQILEEL 2770
Query: 357 TEVERFFLDALHQVKQQ 373
+ + L ++Q+K++
Sbjct: 2771 KKTKMDNLKYVNQLKKE 2787
Score = 43.1 bits (100), Expect = 6e-04
Identities = 66/327 (20%), Positives = 140/327 (42%), Gaps = 50/327 (15%)
Query: 68 KKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINE 127
++ +C++E D K N ++ L+ L ++Q++ + QK ++ +
Sbjct: 810 ERSECRLEAD------QSPKNSAILQNRVDSLEFSL-----ESQKQMNSDLQKQCEELVQ 858
Query: 128 LEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESR 187
++G+ + +KA + Q + + + L+E+ + + ETL LE++
Sbjct: 859 IKGEIEENL---------MKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENK 909
Query: 188 FFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDAL- 246
+E L + E E+A + + + N + KE L + L+ KE ++
Sbjct: 910 -EKELQLLNDKVE------TEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSII 962
Query: 247 ----QKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYM 302
++ + QE+ TL KEIN L +EK M L+Q+ ++ + E ++S +
Sbjct: 963 SLNKREIEELTQENGTL----KEINASLNQEK-MNLIQKS---ESFANYIDEREKSISEL 1014
Query: 303 TKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVERF 362
+ +++ E L L Q + G D L K + + +L+E T +
Sbjct: 1015 SDQYKQEKLILLQRC---EETGNAYED-----LSQKYKAAQEKNSKLECLLNECTSLCEN 1066
Query: 363 FLDALHQVKQQILISRKHYKQIAQAAF 389
+ L Q+K+ +++H + + + AF
Sbjct: 1067 RKNELEQLKE--AFAKEHQEFLTKLAF 1091
Score = 40.0 bits (92), Expect = 0.005
Identities = 45/182 (24%), Positives = 76/182 (41%), Gaps = 20/182 (10%)
Query: 217 QLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIM 276
QL + + + + L+ L H KE Q+LQ L +K +L+ KEK++
Sbjct: 282 QLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQ-----LQLEKAKVELIEKEKVL 336
Query: 277 -----QLVQQRSQIQTLQKKVVNLETALSYMTKEF-------ESEVLKLQQHAMIENQAG 324
+LV+ +Q K LE L +T++ ES L+Q + +
Sbjct: 337 NKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEF 396
Query: 325 QVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVERFF---LDALHQVKQQILISRKHY 381
Q E+ + Q Q D+E ++K L + + LD L VKQQ+ + + +
Sbjct: 397 QEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEF 456
Query: 382 KQ 383
KQ
Sbjct: 457 KQ 458
Score = 39.7 bits (91), Expect = 0.007
Identities = 78/367 (21%), Positives = 150/367 (40%), Gaps = 38/367 (10%)
Query: 5 GKDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSN 64
G K+ S ++ LI+ ES + E ++ELS +Y+ IL +
Sbjct: 977 GTLKEINASLNQEKMNLIQKSESFANYID------EREKSISELSD-QYKQEKLILLQ-- 1027
Query: 65 EDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQ 124
+C+ + LS K QEK++ +E L + E + E ++L++ + ++
Sbjct: 1028 ------RCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKE 1081
Query: 125 INELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRN-TERIHQE--TL 181
E + + + EL+ V+Q + E+ D + N ++ + QE TL
Sbjct: 1082 HQEFLTKLAFAEERNQNLMLELETVQQ------ALRSEMTDNQNNSKSEAGGLKQEIMTL 1135
Query: 182 RRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKEND------YLQKA 235
+ +++ +E + L QE E+ +M + HE ++ RN KE + +
Sbjct: 1136 KEEQNKMQKEVNDLLQENEQ--LMKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQ 1193
Query: 236 LAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNL 295
+ +KE N+Q +Q +L KE+ L EK + +Q Q + NL
Sbjct: 1194 MDLEVKEISLDSYNAQLVQLE--AMLRNKELK-LQESEKEKECLQHELQTIRGDLETSNL 1250
Query: 296 ETALSYM---TKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNI 352
+ S K+ E + + E Q + LQ LQ ++N ++K+ + +
Sbjct: 1251 QDMQSQEISGLKDCEIDAEEKYISGPHELSTSQNDNAHLQCSLQTTMNKLNELEKICEIL 1310
Query: 353 LDERTEV 359
E+ E+
Sbjct: 1311 QAEKYEL 1317
Score = 39.3 bits (90), Expect = 0.009
Identities = 68/361 (18%), Positives = 143/361 (39%), Gaps = 44/361 (12%)
Query: 73 KMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQF 132
K+E+ + S K+ QE + ++ +Q+L+ +++ E ++ +QK T E+E +
Sbjct: 1565 KLEEKMESQGIMKNKEIQELEQLLSSERQELDCLRKQYLSENEQWQQKLTSVTLEMESKL 1624
Query: 133 HQKAKEIGMIHTELKAVR-QFQ--------------KRKIQVERELDDL--KENLRNTER 175
+ K+ + EL+ R Q Q + IQ E D+ + TER
Sbjct: 1625 AAEKKQTEQLSLELEVARLQLQGLDLSSRSLLGIDTEDAIQGRNESCDISKEHTSETTER 1684
Query: 176 IHQETLRRLESRFFEEKHRL-------------------EQEAEKKIIMLAE---RAHHE 213
+ + ++ + ++ L EQ + E + E
Sbjct: 1685 TPKHDVHQICDKDAQQDLNLDIEKITETGAVKPTGECSGEQSPDTNYEPPGEDKTQGSSE 1744
Query: 214 AIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLL--V 271
I +L+ +G N D+L H + + +++ L+ H + +++ LL +
Sbjct: 1745 CISELSFSGPNALVPMDFLGNQEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEM 1804
Query: 272 KEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKL 331
KE +L Q Q+ T + + LE + + KE S++ + ++ ++Q ++
Sbjct: 1805 KELDSKLHLQEVQLMTKIEACIELEKIVGELKKE-NSDLSEKLEYFSCDHQELLQRVETS 1863
Query: 332 QHLLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAAFNL 391
+ L D EM+ K ++I D +V + + V+ ++ R I A L
Sbjct: 1864 EGL--NSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYL 1921
Query: 392 K 392
+
Sbjct: 1922 E 1922
Score = 30.4 bits (67), Expect = 4.2
Identities = 38/142 (26%), Positives = 70/142 (49%), Gaps = 21/142 (14%)
Query: 21 LIKTDESVVDRAKANASLWEARLEVTELSRIKY-----RDTSRILAKSNEDLKK-KQCKM 74
L + E + + KA + E L+ T++ +KY ++ R K +K KQ +
Sbjct: 2749 LKSSKEELNNSLKATTQILE-ELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEE 2807
Query: 75 EKDIM-SVLSYLK-KQDQEK-----DNMIEKLKQQLNETKEKAQE---EKDKLEQKYTRQ 124
EK+I+ LS L+ Q+++K D +++L ++ E KE +E E D+ KY
Sbjct: 2808 EKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSL 2867
Query: 125 INELEGQFHQKAKEIGMIHTEL 146
+ + + +KAKE M+ T++
Sbjct: 2868 L--ISHEKLEKAKE--MLETQV 2885
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 72.4 bits (176), Expect = 1e-12
Identities = 73/395 (18%), Positives = 185/395 (46%), Gaps = 25/395 (6%)
Query: 9 KKGKSKGKDTKKLIKTDESVVDRAKANASL--WEARLEVTELSRIKYRDTSRILAKSNED 66
K+ + KD K + T E + ++ ++N + + R+ E +++ + + +
Sbjct: 345 KEDAAATKDRCKQL-TQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQ 403
Query: 67 LKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQIN 126
++ K ++ + + + +++LK QE + + + N+ + K E +KL Q Y R +N
Sbjct: 404 MQMKFQQVREQMEAEIAHLK---QENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVN 460
Query: 127 ELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLES 186
EL + + +E +A Q + + + ER ++++ +R H+ + L+S
Sbjct: 461 ELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQS 520
Query: 187 RFFEEKHRLEQEAEKKI-IMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDA 245
+F +++ ++ K +++++ + ++QL ++ + + + LQ + L++ +A
Sbjct: 521 KFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEA 580
Query: 246 LQKNSQKLQESHTLLLHQKEINDL------LVKEKIMQLVQQRSQIQTLQKKVVNLETAL 299
L+ ++Q+ H+ + Q + L ++ EK Q+ Q + + + ++ + E L
Sbjct: 581 LK---AQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEEL 637
Query: 300 ---SYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDER 356
M ++EV KLQ A E A E++K+Q + +KD ++ +++ ++ + +
Sbjct: 638 KDIQNMNFLLKAEVQKLQALAN-EQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNK 696
Query: 357 TEVERFFLDALHQVKQQI-----LISRKHYKQIAQ 386
E + D +K ++ L+S + K + +
Sbjct: 697 MEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVE 731
Score = 68.9 bits (167), Expect = 1e-11
Identities = 81/331 (24%), Positives = 151/331 (45%), Gaps = 43/331 (12%)
Query: 71 QCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQE-------EKDKLEQKYTR 123
Q ++K L+ L Q QEKD ++ +K+ TK++ ++ EK++ TR
Sbjct: 316 QDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITR 375
Query: 124 ---QINELEGQFHQKAKEIGMIHTELKAVR-QFQKRKIQVERELDDLKENLRNTERIHQE 179
+I LE + + +I + + E + ++ +FQ+ + Q+E E+ LK+
Sbjct: 376 MKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSN 435
Query: 180 TLRRLESRFFEEKHRLEQEAEKKIIML----------------AERAHHEAIVQLNDAGR 223
T +LES+ E ++L Q+ + + L AE+A + VQL +A R
Sbjct: 436 TTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAER 495
Query: 224 NVFKENDYLQKALAYHLKETDALQKNSQK---LQESHTLLLHQKEINDLLVKEKIMQLVQ 280
+ Y++K A H +A Q++ Q +E+ LH K + L+ K+ QL Q
Sbjct: 496 RWEEVQSYIRKRTAEH----EAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQ---QLEQ 548
Query: 281 QRSQIQTLQKKVVNLETALSYMTKEF--ESEVLKL---QQHAMIENQ-AGQVEIDKLQHL 334
+ Q+ ++K VN E +L ++ ++E LK Q H+ I Q + V ++L +
Sbjct: 549 RLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKV 608
Query: 335 LQMKDREMNRVKKLAKNILDERTEVERFFLD 365
+ KD+++ + + + D T E D
Sbjct: 609 IAEKDKQIKQTEDSLASERDRLTSKEEELKD 639
Score = 53.9 bits (128), Expect = 4e-07
Identities = 90/446 (20%), Positives = 182/446 (40%), Gaps = 82/446 (18%)
Query: 18 TKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAK-------SNEDLKKK 70
T+K K + V + A + + ++++ E R ++ + + K + +DL+ K
Sbjct: 463 TEKTGKLQQEEVQKKNAEQAATQLKVQLQEAER-RWEEVQSYIRKRTAEHEAAQQDLQSK 521
Query: 71 QCKMEKDIMSV-----------------LSYLKKQDQEKDNMIEKLKQQLNETKEKAQEE 113
E ++ S+ L L + +Q++ N E L+ Q+ + E+ +
Sbjct: 522 FVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEAL 581
Query: 114 KDKLEQKYTR---------QINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELD 164
K +++Q +++ EL +K K+I L + R R E EL
Sbjct: 582 KAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERD---RLTSKEEELK 638
Query: 165 DLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEK------KIIMLAERAHHEAIVQ- 217
D+ +N+ + + L+ L + H LE+ + KI +L E+ HE +
Sbjct: 639 DI-QNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKM 697
Query: 218 -----LNDAGRNVFKENDYLQKALAYH------------LKETDALQKNSQKLQESHTLL 260
LND + + E LQ ++ ++E D K ++L E+ +
Sbjct: 698 EEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQ 757
Query: 261 LHQKEI--------NDLLVKE------KIMQLVQQRSQIQTLQKKVVNLETALSYMTKEF 306
+ KE N L KE K V S ++ L+K + + + + +
Sbjct: 758 VATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELL 817
Query: 307 ESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDA 366
E+E+LK+ + ++ +LQ+LL+ K+ +MN +K +L+E+ +
Sbjct: 818 EAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKA----VLEEKEKDLANTGKW 873
Query: 367 LHQVKQQILISRKHYKQIAQAAFNLK 392
L ++++ + H +++AQ NLK
Sbjct: 874 LQDLQEENESLKAHVQEVAQ--HNLK 897
Score = 43.9 bits (102), Expect = 4e-04
Identities = 75/366 (20%), Positives = 155/366 (42%), Gaps = 33/366 (9%)
Query: 10 KGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKK 69
KGK + +T K + ++ ++ AN W L+ E +K + + + +LK+
Sbjct: 847 KGKEEQMNTMKAVLEEK---EKDLANTGKWLQDLQ-EENESLK----AHVQEVAQHNLKE 898
Query: 70 KQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQK--YTRQINE 127
+ + + ++ LK+++ E + LK++ ++ K Q +D ++ + QI +
Sbjct: 899 ASSASQFEELEIV--LKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQ 956
Query: 128 LEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESR 187
L+ Q +Q+A LK + + +K + ELD LK+ + + +R LR
Sbjct: 957 LKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEH-QRKKNNDLREKNWE 1015
Query: 188 FFEEKHRLEQEAEKKIIMLA-ERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDAL 246
E E+ + K+ + ER V+L + V K+ + + ++ +L + L
Sbjct: 1016 AMEALASTEKMLQDKVNKTSKERQQQVEAVELE--AKEVLKKL-FPKVSVPSNLSYGEWL 1072
Query: 247 QKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEF 306
+K +E +E+ L K K + Q++ + K V ET
Sbjct: 1073 HGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAET--------- 1123
Query: 307 ESEVLKLQQHAMIENQAGQVEID-------KLQHLLQMKDREMNRVKKLAKNILDERTEV 359
E + KLQ+ E +V++D ++Q ++E+ R++ K+I + R E
Sbjct: 1124 EGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRRER 1183
Query: 360 ERFFLD 365
E ++
Sbjct: 1184 EHLEME 1189
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 72.4 bits (176), Expect = 1e-12
Identities = 73/395 (18%), Positives = 185/395 (46%), Gaps = 25/395 (6%)
Query: 9 KKGKSKGKDTKKLIKTDESVVDRAKANASL--WEARLEVTELSRIKYRDTSRILAKSNED 66
K+ + KD K + T E + ++ ++N + + R+ E +++ + + +
Sbjct: 345 KEDAAATKDRCKQL-TQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQ 403
Query: 67 LKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQIN 126
++ K ++ + + + +++LK QE + + + N+ + K E +KL Q Y R +N
Sbjct: 404 MQMKFQQVREQMEAEIAHLK---QENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVN 460
Query: 127 ELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLES 186
EL + + +E +A Q + + + ER ++++ +R H+ + L+S
Sbjct: 461 ELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQS 520
Query: 187 RFFEEKHRLEQEAEKKI-IMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDA 245
+F +++ ++ K +++++ + ++QL ++ + + + LQ + L++ +A
Sbjct: 521 KFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEA 580
Query: 246 LQKNSQKLQESHTLLLHQKEINDL------LVKEKIMQLVQQRSQIQTLQKKVVNLETAL 299
L+ ++Q+ H+ + Q + L ++ EK Q+ Q + + + ++ + E L
Sbjct: 581 LK---AQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEEL 637
Query: 300 ---SYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDER 356
M ++EV KLQ A E A E++K+Q + +KD ++ +++ ++ + +
Sbjct: 638 KDIQNMNFLLKAEVQKLQALAN-EQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNK 696
Query: 357 TEVERFFLDALHQVKQQI-----LISRKHYKQIAQ 386
E + D +K ++ L+S + K + +
Sbjct: 697 MEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVE 731
Score = 68.9 bits (167), Expect = 1e-11
Identities = 81/331 (24%), Positives = 151/331 (45%), Gaps = 43/331 (12%)
Query: 71 QCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQE-------EKDKLEQKYTR 123
Q ++K L+ L Q QEKD ++ +K+ TK++ ++ EK++ TR
Sbjct: 316 QDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITR 375
Query: 124 ---QINELEGQFHQKAKEIGMIHTELKAVR-QFQKRKIQVERELDDLKENLRNTERIHQE 179
+I LE + + +I + + E + ++ +FQ+ + Q+E E+ LK+
Sbjct: 376 MKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSN 435
Query: 180 TLRRLESRFFEEKHRLEQEAEKKIIML----------------AERAHHEAIVQLNDAGR 223
T +LES+ E ++L Q+ + + L AE+A + VQL +A R
Sbjct: 436 TTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAER 495
Query: 224 NVFKENDYLQKALAYHLKETDALQKNSQK---LQESHTLLLHQKEINDLLVKEKIMQLVQ 280
+ Y++K A H +A Q++ Q +E+ LH K + L+ K+ QL Q
Sbjct: 496 RWEEVQSYIRKRTAEH----EAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQ---QLEQ 548
Query: 281 QRSQIQTLQKKVVNLETALSYMTKEF--ESEVLKL---QQHAMIENQ-AGQVEIDKLQHL 334
+ Q+ ++K VN E +L ++ ++E LK Q H+ I Q + V ++L +
Sbjct: 549 RLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKV 608
Query: 335 LQMKDREMNRVKKLAKNILDERTEVERFFLD 365
+ KD+++ + + + D T E D
Sbjct: 609 IAEKDKQIKQTEDSLASERDRLTSKEEELKD 639
Score = 44.3 bits (103), Expect = 3e-04
Identities = 92/471 (19%), Positives = 191/471 (40%), Gaps = 51/471 (10%)
Query: 10 KGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKK 69
KGK + +T K + ++ ++ AN W L+ E +K + + + +LK+
Sbjct: 870 KGKEEQMNTMKAVLEEK---EKDLANTGKWLQDLQ-EENESLK----AHVQEVAQHNLKE 921
Query: 70 KQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQK--YTRQINE 127
+ + + ++ LK+++ E + LK++ ++ K Q +D ++ + QI +
Sbjct: 922 ASSASQFEELEIV--LKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQ 979
Query: 128 LEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLK-------------------- 167
L+ Q +Q+A LK + + +K + ELD LK
Sbjct: 980 LKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEA 1039
Query: 168 -ENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVF 226
E L +TE++ Q+ + + ++ +E EA++ + L + + + + + F
Sbjct: 1040 MEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGE-WLHGF 1098
Query: 227 KENDYLQKALAYHLKETDALQKNSQKLQESHTLL-LHQKEINDLLVKEKIMQLVQQRSQI 285
++ A +E L+ ++ E HTLL L ++ +L + + + QRS
Sbjct: 1099 EKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVE 1158
Query: 286 QTLQK---KVVNLETALSYMTKEFESEVLKLQ----QHAMIENQAGQVEIDKLQHLLQMK 338
Q K KV + M F S +L+ ++ IEN + E + L+ L+
Sbjct: 1159 QEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENL--RREREHLEMELEKA 1216
Query: 339 DREMNRVKKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAACT 398
+ E + + + D TE+++ D+ + +Q + +A N + T
Sbjct: 1217 EMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQ-----NEELNLLKAQLNETLTKLRT 1271
Query: 399 GRTEYPKIR-TFDGREHSTNSVNQDLLEAEKWTHIEGNVDIGDLTWEQKEK 448
+ E K+ + S + +++A T + N D+ T E EK
Sbjct: 1272 EQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPET-ESSEK 1321
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 72.4 bits (176), Expect = 1e-12
Identities = 73/395 (18%), Positives = 185/395 (46%), Gaps = 25/395 (6%)
Query: 9 KKGKSKGKDTKKLIKTDESVVDRAKANASL--WEARLEVTELSRIKYRDTSRILAKSNED 66
K+ + KD K + T E + ++ ++N + + R+ E +++ + + +
Sbjct: 345 KEDAAATKDRCKQL-TQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQ 403
Query: 67 LKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQIN 126
++ K ++ + + + +++LK QE + + + N+ + K E +KL Q Y R +N
Sbjct: 404 MQMKFQQVREQMEAEIAHLK---QENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVN 460
Query: 127 ELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLES 186
EL + + +E +A Q + + + ER ++++ +R H+ + L+S
Sbjct: 461 ELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQS 520
Query: 187 RFFEEKHRLEQEAEKKI-IMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDA 245
+F +++ ++ K +++++ + ++QL ++ + + + LQ + L++ +A
Sbjct: 521 KFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEA 580
Query: 246 LQKNSQKLQESHTLLLHQKEINDL------LVKEKIMQLVQQRSQIQTLQKKVVNLETAL 299
L+ ++Q+ H+ + Q + L ++ EK Q+ Q + + + ++ + E L
Sbjct: 581 LK---AQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEEL 637
Query: 300 ---SYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDER 356
M ++EV KLQ A E A E++K+Q + +KD ++ +++ ++ + +
Sbjct: 638 KDIQNMNFLLKAEVQKLQALAN-EQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNK 696
Query: 357 TEVERFFLDALHQVKQQI-----LISRKHYKQIAQ 386
E + D +K ++ L+S + K + +
Sbjct: 697 MEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVE 731
Score = 68.9 bits (167), Expect = 1e-11
Identities = 81/331 (24%), Positives = 151/331 (45%), Gaps = 43/331 (12%)
Query: 71 QCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQE-------EKDKLEQKYTR 123
Q ++K L+ L Q QEKD ++ +K+ TK++ ++ EK++ TR
Sbjct: 316 QDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITR 375
Query: 124 ---QINELEGQFHQKAKEIGMIHTELKAVR-QFQKRKIQVERELDDLKENLRNTERIHQE 179
+I LE + + +I + + E + ++ +FQ+ + Q+E E+ LK+
Sbjct: 376 MKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSN 435
Query: 180 TLRRLESRFFEEKHRLEQEAEKKIIML----------------AERAHHEAIVQLNDAGR 223
T +LES+ E ++L Q+ + + L AE+A + VQL +A R
Sbjct: 436 TTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAER 495
Query: 224 NVFKENDYLQKALAYHLKETDALQKNSQK---LQESHTLLLHQKEINDLLVKEKIMQLVQ 280
+ Y++K A H +A Q++ Q +E+ LH K + L+ K+ QL Q
Sbjct: 496 RWEEVQSYIRKRTAEH----EAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQ---QLEQ 548
Query: 281 QRSQIQTLQKKVVNLETALSYMTKEF--ESEVLKL---QQHAMIENQ-AGQVEIDKLQHL 334
+ Q+ ++K VN E +L ++ ++E LK Q H+ I Q + V ++L +
Sbjct: 549 RLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKV 608
Query: 335 LQMKDREMNRVKKLAKNILDERTEVERFFLD 365
+ KD+++ + + + D T E D
Sbjct: 609 IAEKDKQIKQTEDSLASERDRLTSKEEELKD 639
Score = 48.5 bits (114), Expect = 1e-05
Identities = 77/370 (20%), Positives = 160/370 (43%), Gaps = 39/370 (10%)
Query: 10 KGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKK 69
KGK + +T K + ++ ++ AN W L+ E +K + + + +LK+
Sbjct: 870 KGKEEQMNTMKAVLEEK---EKDLANTGKWLQDLQ-EENESLK----AHVQEVAQHNLKE 921
Query: 70 KQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQK--YTRQINE 127
+ + + ++ LK+++ E + LK++ ++ K Q +D ++ + QI +
Sbjct: 922 ASSASQFEELEIV--LKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQ 979
Query: 128 LEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESR 187
L+ Q +Q+A LK + + +K + ELD LK+ + + + + E +++E+
Sbjct: 980 LKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAV 1039
Query: 188 FFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQ--KALAYHLKETDA 245
E K L ++ K+ + + ++ E + + + K L + LKE D
Sbjct: 1040 ELEAKEVL-KKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEAD- 1097
Query: 246 LQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKE 305
E HTLL + E K K + L + +Q LQ+ V E E
Sbjct: 1098 ---------EMHTLLQLECE------KYKSV-LAETEGILQKLQRSVEQEENKWKVKVDE 1141
Query: 306 FESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVER-FFL 364
+ ++Q Q E+++L+ + KD E R ++ + E+ E+ER ++
Sbjct: 1142 SHKTIKQMQSSFTSSEQ----ELERLRS--ENKDIENLRREREHLEMELEKAEMERSTYV 1195
Query: 365 DALHQVKQQI 374
+ ++K Q+
Sbjct: 1196 TEVRELKAQL 1205
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 72.4 bits (176), Expect = 1e-12
Identities = 73/395 (18%), Positives = 185/395 (46%), Gaps = 25/395 (6%)
Query: 9 KKGKSKGKDTKKLIKTDESVVDRAKANASL--WEARLEVTELSRIKYRDTSRILAKSNED 66
K+ + KD K + T E + ++ ++N + + R+ E +++ + + +
Sbjct: 345 KEDAAATKDRCKQL-TQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQ 403
Query: 67 LKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQIN 126
++ K ++ + + + +++LK QE + + + N+ + K E +KL Q Y R +N
Sbjct: 404 MQMKFQQVREQMEAEIAHLK---QENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVN 460
Query: 127 ELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLES 186
EL + + +E +A Q + + + ER ++++ +R H+ + L+S
Sbjct: 461 ELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQS 520
Query: 187 RFFEEKHRLEQEAEKKI-IMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDA 245
+F +++ ++ K +++++ + ++QL ++ + + + LQ + L++ +A
Sbjct: 521 KFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEA 580
Query: 246 LQKNSQKLQESHTLLLHQKEINDL------LVKEKIMQLVQQRSQIQTLQKKVVNLETAL 299
L+ ++Q+ H+ + Q + L ++ EK Q+ Q + + + ++ + E L
Sbjct: 581 LK---AQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEEL 637
Query: 300 ---SYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDER 356
M ++EV KLQ A E A E++K+Q + +KD ++ +++ ++ + +
Sbjct: 638 KDIQNMNFLLKAEVQKLQALAN-EQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNK 696
Query: 357 TEVERFFLDALHQVKQQI-----LISRKHYKQIAQ 386
E + D +K ++ L+S + K + +
Sbjct: 697 MEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVE 731
Score = 68.9 bits (167), Expect = 1e-11
Identities = 81/331 (24%), Positives = 151/331 (45%), Gaps = 43/331 (12%)
Query: 71 QCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQE-------EKDKLEQKYTR 123
Q ++K L+ L Q QEKD ++ +K+ TK++ ++ EK++ TR
Sbjct: 316 QDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITR 375
Query: 124 ---QINELEGQFHQKAKEIGMIHTELKAVR-QFQKRKIQVERELDDLKENLRNTERIHQE 179
+I LE + + +I + + E + ++ +FQ+ + Q+E E+ LK+
Sbjct: 376 MKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSN 435
Query: 180 TLRRLESRFFEEKHRLEQEAEKKIIML----------------AERAHHEAIVQLNDAGR 223
T +LES+ E ++L Q+ + + L AE+A + VQL +A R
Sbjct: 436 TTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAER 495
Query: 224 NVFKENDYLQKALAYHLKETDALQKNSQK---LQESHTLLLHQKEINDLLVKEKIMQLVQ 280
+ Y++K A H +A Q++ Q +E+ LH K + L+ K+ QL Q
Sbjct: 496 RWEEVQSYIRKRTAEH----EAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQ---QLEQ 548
Query: 281 QRSQIQTLQKKVVNLETALSYMTKEF--ESEVLKL---QQHAMIENQ-AGQVEIDKLQHL 334
+ Q+ ++K VN E +L ++ ++E LK Q H+ I Q + V ++L +
Sbjct: 549 RLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKV 608
Query: 335 LQMKDREMNRVKKLAKNILDERTEVERFFLD 365
+ KD+++ + + + D T E D
Sbjct: 609 IAEKDKQIKQTEDSLASERDRLTSKEEELKD 639
Score = 44.3 bits (103), Expect = 3e-04
Identities = 92/471 (19%), Positives = 191/471 (40%), Gaps = 51/471 (10%)
Query: 10 KGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKK 69
KGK + +T K + ++ ++ AN W L+ E +K + + + +LK+
Sbjct: 870 KGKEEQMNTMKAVLEEK---EKDLANTGKWLQDLQ-EENESLK----AHVQEVAQHNLKE 921
Query: 70 KQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQK--YTRQINE 127
+ + + ++ LK+++ E + LK++ ++ K Q +D ++ + QI +
Sbjct: 922 ASSASQFEELEIV--LKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQ 979
Query: 128 LEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLK-------------------- 167
L+ Q +Q+A LK + + +K + ELD LK
Sbjct: 980 LKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEA 1039
Query: 168 -ENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVF 226
E L +TE++ Q+ + + ++ +E EA++ + L + + + + + F
Sbjct: 1040 MEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGE-WLHGF 1098
Query: 227 KENDYLQKALAYHLKETDALQKNSQKLQESHTLL-LHQKEINDLLVKEKIMQLVQQRSQI 285
++ A +E L+ ++ E HTLL L ++ +L + + + QRS
Sbjct: 1099 EKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVE 1158
Query: 286 QTLQK---KVVNLETALSYMTKEFESEVLKLQ----QHAMIENQAGQVEIDKLQHLLQMK 338
Q K KV + M F S +L+ ++ IEN + E + L+ L+
Sbjct: 1159 QEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENL--RREREHLEMELEKA 1216
Query: 339 DREMNRVKKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAACT 398
+ E + + + D TE+++ D+ + +Q + +A N + T
Sbjct: 1217 EMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQ-----NEELNLLKAQLNETLTKLRT 1271
Query: 399 GRTEYPKIR-TFDGREHSTNSVNQDLLEAEKWTHIEGNVDIGDLTWEQKEK 448
+ E K+ + S + +++A T + N D+ T E EK
Sbjct: 1272 EQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPET-ESSEK 1321
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 72.0 bits (175), Expect = 1e-12
Identities = 91/381 (23%), Positives = 171/381 (44%), Gaps = 61/381 (16%)
Query: 14 KGKDTKKLIKT----DESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKK 69
K KDT K T DE+ + N + E +V+ELS++ Y++ L ED +K
Sbjct: 613 KLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQL-YKEAQAEL----EDYRK 667
Query: 70 KQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELE 129
+ K +D+ + Y+ K + EK L Q N ++ KA++ +++ +Y++ +NEL
Sbjct: 668 R--KSLEDVTA--EYIHKAEHEK------LMQLTNVSRAKAEDALSEMKSQYSKVLNELT 717
Query: 130 --GQFHQKAKEIGMIHTE-LKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLES 186
Q KE + TE L+ + + ++E ++ +LKE+L + E + +LE
Sbjct: 718 QLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE----VEVAKLEK 773
Query: 187 RFFEEK-------------HRLEQEAEKKIIMLAERAH---------HEAIVQLNDAGRN 224
+ EEK +L+ E ++ +LA + H +VQ+
Sbjct: 774 QLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQ 833
Query: 225 VFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQ 284
V +E + +Q L +E + L + Q+ QE + E + L ++K ++ + +
Sbjct: 834 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKE 893
Query: 285 IQTLQKKVVNLETALSYMTKEFESEVLKL----QQHAMIENQAGQVEIDKLQ-------H 333
+ L K+ +N + LSY T + + +L QQ ++NQ + + + H
Sbjct: 894 VTKL-KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMH 952
Query: 334 LLQMKDREMNR-VKKLAKNIL 353
LL +M+ V+K+ K IL
Sbjct: 953 LLYAVQGQMDEDVQKVLKQIL 973
Score = 52.8 bits (125), Expect = 8e-07
Identities = 87/441 (19%), Positives = 180/441 (40%), Gaps = 104/441 (23%)
Query: 16 KDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKME 75
+D +K +++ E+ +R + L R E+ L+ + + S L++ ++ + K +
Sbjct: 442 QDLQKRLESSEA--ERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAM 499
Query: 76 KDIMSVLSYLKK---QDQEKDNM------------IEKLKQQLNETKEKAQEEKDKLEQK 120
K+++SV +K + DN I LKQ L E+++ K+K+ +
Sbjct: 500 KEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVREL 559
Query: 121 YTRQINELEG---------------------------------QFHQKAKEIGMIHTELK 147
+ + +G ++ + +EI + LK
Sbjct: 560 EEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLK 619
Query: 148 ------AVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEK 201
A + + K + R +D+L + + ++++E LE + ++ LE +
Sbjct: 620 SQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELED--YRKRKSLEDVTAE 677
Query: 202 KIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKE----------TDALQKNS- 250
I +A HE ++QL + R K D L + + + K DA ++NS
Sbjct: 678 YI----HKAEHEKLMQLTNVSR--AKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSV 731
Query: 251 ---QKLQESHTLLLHQKEINDLL--VKEKI-----------MQLVQQ----------RSQ 284
+ LQ TL KE+ + + +KE + QL+++ RS
Sbjct: 732 SITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSS 791
Query: 285 IQTLQKKVVNLETALSYMTKEFESEVLKLQQHAM-IENQAGQVEIDK--LQHLLQMKDRE 341
+ LQ + + + L+ KE E K+ + I ++ QV+ +K +Q LL+ K++E
Sbjct: 792 YEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQE 851
Query: 342 MNRVKKLAKNILDERTEVERF 362
+N + + + +E E++R+
Sbjct: 852 VNELLQKFQQAQEELAEMKRY 872
Score = 34.7 bits (78), Expect = 0.22
Identities = 44/237 (18%), Positives = 102/237 (43%), Gaps = 17/237 (7%)
Query: 141 MIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAE 200
+IH+ K+ R Q++ L DL++ L ++E ++ L+SR E E
Sbjct: 419 LIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEIS 478
Query: 201 KKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLL 260
+ L+++ + + KE +QK + L +++ S H L
Sbjct: 479 ENSSDLSQK-----LKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYS----HFHELR 529
Query: 261 LHQKEINDLL--VKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAM 318
+ ++EIN L ++ + + + + +++ L++K+V E E E +K ++
Sbjct: 530 VTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSV 589
Query: 319 IENQAGQVEI------DKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQ 369
IEN + + + ++++KD +++ + A + ++ E +D L++
Sbjct: 590 IENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNK 646
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 72.0 bits (175), Expect = 1e-12
Identities = 91/381 (23%), Positives = 171/381 (44%), Gaps = 61/381 (16%)
Query: 14 KGKDTKKLIKT----DESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKK 69
K KDT K T DE+ + N + E +V+ELS++ Y++ L ED +K
Sbjct: 602 KLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQL-YKEAQAEL----EDYRK 656
Query: 70 KQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELE 129
+ K +D+ + Y+ K + EK L Q N ++ KA++ +++ +Y++ +NEL
Sbjct: 657 R--KSLEDVTA--EYIHKAEHEK------LMQLTNVSRAKAEDALSEMKSQYSKVLNELT 706
Query: 130 --GQFHQKAKEIGMIHTE-LKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLES 186
Q KE + TE L+ + + ++E ++ +LKE+L + E + +LE
Sbjct: 707 QLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE----VEVAKLEK 762
Query: 187 RFFEEK-------------HRLEQEAEKKIIMLAERAH---------HEAIVQLNDAGRN 224
+ EEK +L+ E ++ +LA + H +VQ+
Sbjct: 763 QLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQ 822
Query: 225 VFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQ 284
V +E + +Q L +E + L + Q+ QE + E + L ++K ++ + +
Sbjct: 823 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKE 882
Query: 285 IQTLQKKVVNLETALSYMTKEFESEVLKL----QQHAMIENQAGQVEIDKLQ-------H 333
+ L K+ +N + LSY T + + +L QQ ++NQ + + + H
Sbjct: 883 VTKL-KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMH 941
Query: 334 LLQMKDREMNR-VKKLAKNIL 353
LL +M+ V+K+ K IL
Sbjct: 942 LLYAVQGQMDEDVQKVLKQIL 962
Score = 52.8 bits (125), Expect = 8e-07
Identities = 87/441 (19%), Positives = 180/441 (40%), Gaps = 104/441 (23%)
Query: 16 KDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKME 75
+D +K +++ E+ +R + L R E+ L+ + + S L++ ++ + K +
Sbjct: 431 QDLQKRLESSEA--ERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAM 488
Query: 76 KDIMSVLSYLKK---QDQEKDNM------------IEKLKQQLNETKEKAQEEKDKLEQK 120
K+++SV +K + DN I LKQ L E+++ K+K+ +
Sbjct: 489 KEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVREL 548
Query: 121 YTRQINELEG---------------------------------QFHQKAKEIGMIHTELK 147
+ + +G ++ + +EI + LK
Sbjct: 549 EEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLK 608
Query: 148 ------AVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEK 201
A + + K + R +D+L + + ++++E LE + ++ LE +
Sbjct: 609 SQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELED--YRKRKSLEDVTAE 666
Query: 202 KIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKE----------TDALQKNS- 250
I +A HE ++QL + R K D L + + + K DA ++NS
Sbjct: 667 YI----HKAEHEKLMQLTNVSR--AKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSV 720
Query: 251 ---QKLQESHTLLLHQKEINDLL--VKEKI-----------MQLVQQ----------RSQ 284
+ LQ TL KE+ + + +KE + QL+++ RS
Sbjct: 721 SITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSS 780
Query: 285 IQTLQKKVVNLETALSYMTKEFESEVLKLQQHAM-IENQAGQVEIDK--LQHLLQMKDRE 341
+ LQ + + + L+ KE E K+ + I ++ QV+ +K +Q LL+ K++E
Sbjct: 781 YEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQE 840
Query: 342 MNRVKKLAKNILDERTEVERF 362
+N + + + +E E++R+
Sbjct: 841 VNELLQKFQQAQEELAEMKRY 861
Score = 34.7 bits (78), Expect = 0.22
Identities = 44/237 (18%), Positives = 102/237 (43%), Gaps = 17/237 (7%)
Query: 141 MIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAE 200
+IH+ K+ R Q++ L DL++ L ++E ++ L+SR E E
Sbjct: 408 LIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEIS 467
Query: 201 KKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLL 260
+ L+++ + + KE +QK + L +++ S H L
Sbjct: 468 ENSSDLSQK-----LKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYS----HFHELR 518
Query: 261 LHQKEINDLL--VKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAM 318
+ ++EIN L ++ + + + + +++ L++K+V E E E +K ++
Sbjct: 519 VTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSV 578
Query: 319 IENQAGQVEI------DKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQ 369
IEN + + + ++++KD +++ + A + ++ E +D L++
Sbjct: 579 IENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNK 635
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 72.0 bits (175), Expect = 1e-12
Identities = 91/381 (23%), Positives = 171/381 (44%), Gaps = 61/381 (16%)
Query: 14 KGKDTKKLIKT----DESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKK 69
K KDT K T DE+ + N + E +V+ELS++ Y++ L ED +K
Sbjct: 581 KLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQL-YKEAQAEL----EDYRK 635
Query: 70 KQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELE 129
+ K +D+ + Y+ K + EK L Q N ++ KA++ +++ +Y++ +NEL
Sbjct: 636 R--KSLEDVTA--EYIHKAEHEK------LMQLTNVSRAKAEDALSEMKSQYSKVLNELT 685
Query: 130 --GQFHQKAKEIGMIHTE-LKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLES 186
Q KE + TE L+ + + ++E ++ +LKE+L + E + +LE
Sbjct: 686 QLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE----VEVAKLEK 741
Query: 187 RFFEEK-------------HRLEQEAEKKIIMLAERAH---------HEAIVQLNDAGRN 224
+ EEK +L+ E ++ +LA + H +VQ+
Sbjct: 742 QLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQ 801
Query: 225 VFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQ 284
V +E + +Q L +E + L + Q+ QE + E + L ++K ++ + +
Sbjct: 802 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKE 861
Query: 285 IQTLQKKVVNLETALSYMTKEFESEVLKL----QQHAMIENQAGQVEIDKLQ-------H 333
+ L K+ +N + LSY T + + +L QQ ++NQ + + + H
Sbjct: 862 VTKL-KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMH 920
Query: 334 LLQMKDREMNR-VKKLAKNIL 353
LL +M+ V+K+ K IL
Sbjct: 921 LLYAVQGQMDEDVQKVLKQIL 941
Score = 52.8 bits (125), Expect = 8e-07
Identities = 87/441 (19%), Positives = 180/441 (40%), Gaps = 104/441 (23%)
Query: 16 KDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKME 75
+D +K +++ E+ +R + L R E+ L+ + + S L++ ++ + K +
Sbjct: 410 QDLQKRLESSEA--ERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAM 467
Query: 76 KDIMSVLSYLKK---QDQEKDNM------------IEKLKQQLNETKEKAQEEKDKLEQK 120
K+++SV +K + DN I LKQ L E+++ K+K+ +
Sbjct: 468 KEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVREL 527
Query: 121 YTRQINELEG---------------------------------QFHQKAKEIGMIHTELK 147
+ + +G ++ + +EI + LK
Sbjct: 528 EEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLK 587
Query: 148 ------AVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEK 201
A + + K + R +D+L + + ++++E LE + ++ LE +
Sbjct: 588 SQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELED--YRKRKSLEDVTAE 645
Query: 202 KIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKE----------TDALQKNS- 250
I +A HE ++QL + R K D L + + + K DA ++NS
Sbjct: 646 YI----HKAEHEKLMQLTNVSR--AKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSV 699
Query: 251 ---QKLQESHTLLLHQKEINDLL--VKEKI-----------MQLVQQ----------RSQ 284
+ LQ TL KE+ + + +KE + QL+++ RS
Sbjct: 700 SITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSS 759
Query: 285 IQTLQKKVVNLETALSYMTKEFESEVLKLQQHAM-IENQAGQVEIDK--LQHLLQMKDRE 341
+ LQ + + + L+ KE E K+ + I ++ QV+ +K +Q LL+ K++E
Sbjct: 760 YEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQE 819
Query: 342 MNRVKKLAKNILDERTEVERF 362
+N + + + +E E++R+
Sbjct: 820 VNELLQKFQQAQEELAEMKRY 840
Score = 34.7 bits (78), Expect = 0.22
Identities = 44/237 (18%), Positives = 102/237 (43%), Gaps = 17/237 (7%)
Query: 141 MIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAE 200
+IH+ K+ R Q++ L DL++ L ++E ++ L+SR E E
Sbjct: 387 LIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEIS 446
Query: 201 KKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLL 260
+ L+++ + + KE +QK + L +++ S H L
Sbjct: 447 ENSSDLSQK-----LKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYS----HFHELR 497
Query: 261 LHQKEINDLL--VKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAM 318
+ ++EIN L ++ + + + + +++ L++K+V E E E +K ++
Sbjct: 498 VTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSV 557
Query: 319 IENQAGQVEI------DKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQ 369
IEN + + + ++++KD +++ + A + ++ E +D L++
Sbjct: 558 IENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNK 614
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 72.0 bits (175), Expect = 1e-12
Identities = 91/381 (23%), Positives = 171/381 (44%), Gaps = 61/381 (16%)
Query: 14 KGKDTKKLIKT----DESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKK 69
K KDT K T DE+ + N + E +V+ELS++ Y++ L ED +K
Sbjct: 610 KLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQL-YKEAQAEL----EDYRK 664
Query: 70 KQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELE 129
+ K +D+ + Y+ K + EK L Q N ++ KA++ +++ +Y++ +NEL
Sbjct: 665 R--KSLEDVTA--EYIHKAEHEK------LMQLTNVSRAKAEDALSEMKSQYSKVLNELT 714
Query: 130 --GQFHQKAKEIGMIHTE-LKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLES 186
Q KE + TE L+ + + ++E ++ +LKE+L + E + +LE
Sbjct: 715 QLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE----VEVAKLEK 770
Query: 187 RFFEEK-------------HRLEQEAEKKIIMLAERAH---------HEAIVQLNDAGRN 224
+ EEK +L+ E ++ +LA + H +VQ+
Sbjct: 771 QLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQ 830
Query: 225 VFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQ 284
V +E + +Q L +E + L + Q+ QE + E + L ++K ++ + +
Sbjct: 831 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKE 890
Query: 285 IQTLQKKVVNLETALSYMTKEFESEVLKL----QQHAMIENQAGQVEIDKLQ-------H 333
+ L K+ +N + LSY T + + +L QQ ++NQ + + + H
Sbjct: 891 VTKL-KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMH 949
Query: 334 LLQMKDREMNR-VKKLAKNIL 353
LL +M+ V+K+ K IL
Sbjct: 950 LLYAVQGQMDEDVQKVLKQIL 970
Score = 52.8 bits (125), Expect = 8e-07
Identities = 87/441 (19%), Positives = 180/441 (40%), Gaps = 104/441 (23%)
Query: 16 KDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKME 75
+D +K +++ E+ +R + L R E+ L+ + + S L++ ++ + K +
Sbjct: 439 QDLQKRLESSEA--ERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAM 496
Query: 76 KDIMSVLSYLKK---QDQEKDNM------------IEKLKQQLNETKEKAQEEKDKLEQK 120
K+++SV +K + DN I LKQ L E+++ K+K+ +
Sbjct: 497 KEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVREL 556
Query: 121 YTRQINELEG---------------------------------QFHQKAKEIGMIHTELK 147
+ + +G ++ + +EI + LK
Sbjct: 557 EEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLK 616
Query: 148 ------AVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEK 201
A + + K + R +D+L + + ++++E LE + ++ LE +
Sbjct: 617 SQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELED--YRKRKSLEDVTAE 674
Query: 202 KIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKE----------TDALQKNS- 250
I +A HE ++QL + R K D L + + + K DA ++NS
Sbjct: 675 YI----HKAEHEKLMQLTNVSR--AKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSV 728
Query: 251 ---QKLQESHTLLLHQKEINDLL--VKEKI-----------MQLVQQ----------RSQ 284
+ LQ TL KE+ + + +KE + QL+++ RS
Sbjct: 729 SITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSS 788
Query: 285 IQTLQKKVVNLETALSYMTKEFESEVLKLQQHAM-IENQAGQVEIDK--LQHLLQMKDRE 341
+ LQ + + + L+ KE E K+ + I ++ QV+ +K +Q LL+ K++E
Sbjct: 789 YEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQE 848
Query: 342 MNRVKKLAKNILDERTEVERF 362
+N + + + +E E++R+
Sbjct: 849 VNELLQKFQQAQEELAEMKRY 869
Score = 34.7 bits (78), Expect = 0.22
Identities = 44/237 (18%), Positives = 102/237 (43%), Gaps = 17/237 (7%)
Query: 141 MIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAE 200
+IH+ K+ R Q++ L DL++ L ++E ++ L+SR E E
Sbjct: 416 LIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEIS 475
Query: 201 KKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLL 260
+ L+++ + + KE +QK + L +++ S H L
Sbjct: 476 ENSSDLSQK-----LKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYS----HFHELR 526
Query: 261 LHQKEINDLL--VKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAM 318
+ ++EIN L ++ + + + + +++ L++K+V E E E +K ++
Sbjct: 527 VTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSV 586
Query: 319 IENQAGQVEI------DKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQ 369
IEN + + + ++++KD +++ + A + ++ E +D L++
Sbjct: 587 IENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNK 643
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 72.0 bits (175), Expect = 1e-12
Identities = 91/381 (23%), Positives = 171/381 (44%), Gaps = 61/381 (16%)
Query: 14 KGKDTKKLIKT----DESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKK 69
K KDT K T DE+ + N + E +V+ELS++ Y++ L ED +K
Sbjct: 610 KLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQL-YKEAQAEL----EDYRK 664
Query: 70 KQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELE 129
+ K +D+ + Y+ K + EK L Q N ++ KA++ +++ +Y++ +NEL
Sbjct: 665 R--KSLEDVTA--EYIHKAEHEK------LMQLTNVSRAKAEDALSEMKSQYSKVLNELT 714
Query: 130 --GQFHQKAKEIGMIHTE-LKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLES 186
Q KE + TE L+ + + ++E ++ +LKE+L + E + +LE
Sbjct: 715 QLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE----VEVAKLEK 770
Query: 187 RFFEEK-------------HRLEQEAEKKIIMLAERAH---------HEAIVQLNDAGRN 224
+ EEK +L+ E ++ +LA + H +VQ+
Sbjct: 771 QLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQ 830
Query: 225 VFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQ 284
V +E + +Q L +E + L + Q+ QE + E + L ++K ++ + +
Sbjct: 831 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKE 890
Query: 285 IQTLQKKVVNLETALSYMTKEFESEVLKL----QQHAMIENQAGQVEIDKLQ-------H 333
+ L K+ +N + LSY T + + +L QQ ++NQ + + + H
Sbjct: 891 VTKL-KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMH 949
Query: 334 LLQMKDREMNR-VKKLAKNIL 353
LL +M+ V+K+ K IL
Sbjct: 950 LLYAVQGQMDEDVQKVLKQIL 970
Score = 52.8 bits (125), Expect = 8e-07
Identities = 87/441 (19%), Positives = 180/441 (40%), Gaps = 104/441 (23%)
Query: 16 KDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKME 75
+D +K +++ E+ +R + L R E+ L+ + + S L++ ++ + K +
Sbjct: 439 QDLQKRLESSEA--ERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAM 496
Query: 76 KDIMSVLSYLKK---QDQEKDNM------------IEKLKQQLNETKEKAQEEKDKLEQK 120
K+++SV +K + DN I LKQ L E+++ K+K+ +
Sbjct: 497 KEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVREL 556
Query: 121 YTRQINELEG---------------------------------QFHQKAKEIGMIHTELK 147
+ + +G ++ + +EI + LK
Sbjct: 557 EEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLK 616
Query: 148 ------AVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEK 201
A + + K + R +D+L + + ++++E LE + ++ LE +
Sbjct: 617 SQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELED--YRKRKSLEDVTAE 674
Query: 202 KIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKE----------TDALQKNS- 250
I +A HE ++QL + R K D L + + + K DA ++NS
Sbjct: 675 YI----HKAEHEKLMQLTNVSR--AKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSV 728
Query: 251 ---QKLQESHTLLLHQKEINDLL--VKEKI-----------MQLVQQ----------RSQ 284
+ LQ TL KE+ + + +KE + QL+++ RS
Sbjct: 729 SITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSS 788
Query: 285 IQTLQKKVVNLETALSYMTKEFESEVLKLQQHAM-IENQAGQVEIDK--LQHLLQMKDRE 341
+ LQ + + + L+ KE E K+ + I ++ QV+ +K +Q LL+ K++E
Sbjct: 789 YEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQE 848
Query: 342 MNRVKKLAKNILDERTEVERF 362
+N + + + +E E++R+
Sbjct: 849 VNELLQKFQQAQEELAEMKRY 869
Score = 34.7 bits (78), Expect = 0.22
Identities = 44/237 (18%), Positives = 102/237 (43%), Gaps = 17/237 (7%)
Query: 141 MIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAE 200
+IH+ K+ R Q++ L DL++ L ++E ++ L+SR E E
Sbjct: 416 LIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEIS 475
Query: 201 KKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLL 260
+ L+++ + + KE +QK + L +++ S H L
Sbjct: 476 ENSSDLSQK-----LKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYS----HFHELR 526
Query: 261 LHQKEINDLL--VKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAM 318
+ ++EIN L ++ + + + + +++ L++K+V E E E +K ++
Sbjct: 527 VTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSV 586
Query: 319 IENQAGQVEI------DKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQ 369
IEN + + + ++++KD +++ + A + ++ E +D L++
Sbjct: 587 IENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNK 643
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 72.0 bits (175), Expect = 1e-12
Identities = 91/381 (23%), Positives = 171/381 (44%), Gaps = 61/381 (16%)
Query: 14 KGKDTKKLIKT----DESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKK 69
K KDT K T DE+ + N + E +V+ELS++ Y++ L ED +K
Sbjct: 610 KLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQL-YKEAQAEL----EDYRK 664
Query: 70 KQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELE 129
+ K +D+ + Y+ K + EK L Q N ++ KA++ +++ +Y++ +NEL
Sbjct: 665 R--KSLEDVTA--EYIHKAEHEK------LMQLTNVSRAKAEDALSEMKSQYSKVLNELT 714
Query: 130 --GQFHQKAKEIGMIHTE-LKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLES 186
Q KE + TE L+ + + ++E ++ +LKE+L + E + +LE
Sbjct: 715 QLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE----VEVAKLEK 770
Query: 187 RFFEEK-------------HRLEQEAEKKIIMLAERAH---------HEAIVQLNDAGRN 224
+ EEK +L+ E ++ +LA + H +VQ+
Sbjct: 771 QLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQ 830
Query: 225 VFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQ 284
V +E + +Q L +E + L + Q+ QE + E + L ++K ++ + +
Sbjct: 831 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKE 890
Query: 285 IQTLQKKVVNLETALSYMTKEFESEVLKL----QQHAMIENQAGQVEIDKLQ-------H 333
+ L K+ +N + LSY T + + +L QQ ++NQ + + + H
Sbjct: 891 VTKL-KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMH 949
Query: 334 LLQMKDREMNR-VKKLAKNIL 353
LL +M+ V+K+ K IL
Sbjct: 950 LLYAVQGQMDEDVQKVLKQIL 970
Score = 52.8 bits (125), Expect = 8e-07
Identities = 87/441 (19%), Positives = 180/441 (40%), Gaps = 104/441 (23%)
Query: 16 KDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKME 75
+D +K +++ E+ +R + L R E+ L+ + + S L++ ++ + K +
Sbjct: 439 QDLQKRLESSEA--ERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAM 496
Query: 76 KDIMSVLSYLKK---QDQEKDNM------------IEKLKQQLNETKEKAQEEKDKLEQK 120
K+++SV +K + DN I LKQ L E+++ K+K+ +
Sbjct: 497 KEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVREL 556
Query: 121 YTRQINELEG---------------------------------QFHQKAKEIGMIHTELK 147
+ + +G ++ + +EI + LK
Sbjct: 557 EEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLK 616
Query: 148 ------AVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEK 201
A + + K + R +D+L + + ++++E LE + ++ LE +
Sbjct: 617 SQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELED--YRKRKSLEDVTAE 674
Query: 202 KIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKE----------TDALQKNS- 250
I +A HE ++QL + R K D L + + + K DA ++NS
Sbjct: 675 YI----HKAEHEKLMQLTNVSR--AKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSV 728
Query: 251 ---QKLQESHTLLLHQKEINDLL--VKEKI-----------MQLVQQ----------RSQ 284
+ LQ TL KE+ + + +KE + QL+++ RS
Sbjct: 729 SITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSS 788
Query: 285 IQTLQKKVVNLETALSYMTKEFESEVLKLQQHAM-IENQAGQVEIDK--LQHLLQMKDRE 341
+ LQ + + + L+ KE E K+ + I ++ QV+ +K +Q LL+ K++E
Sbjct: 789 YEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQE 848
Query: 342 MNRVKKLAKNILDERTEVERF 362
+N + + + +E E++R+
Sbjct: 849 VNELLQKFQQAQEELAEMKRY 869
Score = 34.7 bits (78), Expect = 0.22
Identities = 44/237 (18%), Positives = 102/237 (43%), Gaps = 17/237 (7%)
Query: 141 MIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAE 200
+IH+ K+ R Q++ L DL++ L ++E ++ L+SR E E
Sbjct: 416 LIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEIS 475
Query: 201 KKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLL 260
+ L+++ + + KE +QK + L +++ S H L
Sbjct: 476 ENSSDLSQK-----LKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYS----HFHELR 526
Query: 261 LHQKEINDLL--VKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAM 318
+ ++EIN L ++ + + + + +++ L++K+V E E E +K ++
Sbjct: 527 VTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSV 586
Query: 319 IENQAGQVEI------DKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQ 369
IEN + + + ++++KD +++ + A + ++ E +D L++
Sbjct: 587 IENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNK 643
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 71.6 bits (174), Expect = 2e-12
Identities = 98/464 (21%), Positives = 203/464 (43%), Gaps = 60/464 (12%)
Query: 6 KDKKKGKSKGKD-TKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSN 64
K+K ++K K+ T+++ DE++ +K +L E + + + + D IL K+
Sbjct: 969 KEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAE-EDKVNILTKAK 1027
Query: 65 EDLKKK------QCKMEKDIMSVLSYLKKQ-------DQEKDNMIEKLKQQLNETKEKAQ 111
L+++ + EK + L K++ QE +E KQQL+E EK +
Sbjct: 1028 TKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKE 1087
Query: 112 ----------EEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVER 161
E++ +E + ++I EL+ + + +EI E + + +K++ + R
Sbjct: 1088 FEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEI---EAERASRAKAEKQRSDLSR 1144
Query: 162 ELDDLKENLRNT---ERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLA--ERAHHEAIV 216
EL+++ E L E ++ E+ F + + LE+ + M+A + H +++
Sbjct: 1145 ELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMA 1204
Query: 217 QLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLH-----QKEINDLLV 271
+L + N+ + L+K + ETD L N++ + ++ L + ++++L
Sbjct: 1205 ELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKT 1264
Query: 272 KEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKL 331
KE+ +Q+ I L + L+T +++ + + + Q + QA +I++L
Sbjct: 1265 KEE-----EQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSR-SKQASTQQIEEL 1318
Query: 332 QHLLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAAFNL 391
+H L+ + + AKN L + R D L + ++ + K Q A +
Sbjct: 1319 KHQLEEETK--------AKNALAHALQSSRHDCDLLREQYEE----EQEGKAELQRALSK 1366
Query: 392 KMRAACTGRTEY--PKIRTFDGREHSTNSVNQDLLEAEKWTHIE 433
RT+Y I+ + E + + Q L EAE+ H+E
Sbjct: 1367 ANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE--HVE 1408
Score = 52.0 bits (123), Expect = 1e-06
Identities = 74/375 (19%), Positives = 167/375 (44%), Gaps = 27/375 (7%)
Query: 19 KKLIKTDESVVDRAKANASLWEARLEV--TELSRIKYRDTSRILAKSNEDLKKKQCKMEK 76
K L+K+ E+ + A + + E+ +E R + + L K DL Q +++
Sbjct: 840 KPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDL---QLQVQS 896
Query: 77 DIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKA 136
+ S+ ++ +Q N I+ L+ ++ E E+A+EE++ + + T + +LE + +
Sbjct: 897 EADSLADAEERCEQLIKNKIQ-LEAKIKEVTERAEEEEE-INAELTAKKRKLEDECSELK 954
Query: 137 KEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRL--ESRFFEEKHR 194
K+I + L V +K K E ++ +L E + + ET+ +L E + +E H+
Sbjct: 955 KDIDDLELTLAKV---EKEKHATENKVKNLTEEMAGLD----ETIAKLSKEKKALQETHQ 1007
Query: 195 L---EQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDY---LQKALAYHLKETDALQK 248
+ +AE+ + + +A + Q++D ++ +E L++A + Q+
Sbjct: 1008 QTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQE 1067
Query: 249 NSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFES 308
++ ++ L + E + + I ++ +++ LQKK+ L+ + + +E E+
Sbjct: 1068 STMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEA 1127
Query: 309 EVLKLQQHAMIENQAGQV--EIDKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDA 366
E A E Q + E++++ L+ + +L K E ++ R +A
Sbjct: 1128 E---RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEA 1184
Query: 367 LHQVKQQILISRKHY 381
Q + + RK +
Sbjct: 1185 TLQHEAMVAALRKKH 1199
Score = 50.8 bits (120), Expect = 3e-06
Identities = 71/354 (20%), Positives = 157/354 (44%), Gaps = 32/354 (9%)
Query: 9 KKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLE--VTELSRIKYRDTSRILAKSNED 66
+K KS+ K + ++ + +AK N LE V+EL + K + R++ D
Sbjct: 1221 EKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSEL-KTKEEEQQRLI----ND 1275
Query: 67 LKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQIN 126
L ++ +++ + +Q EKD ++ +L + + ++ +E K +LE++ T+ N
Sbjct: 1276 LTAQRARLQTEA----GEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEE-TKAKN 1330
Query: 127 ELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLES 186
L + ++ + + + Q+ K +++R L + N+E T + E+
Sbjct: 1331 ALAHALQSSRHDCDLLREQYE---EEQEGKAELQRAL-----SKANSEVAQWRT--KYET 1380
Query: 187 RFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDAL 246
+ LE EA+KK+ + A E + +N ++ K LQ E + L
Sbjct: 1381 DAIQRTEELE-EAKKKLAQRLQEA-EEHVEAVNAKCASLEKTKQRLQ-------NEVEDL 1431
Query: 247 QKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEF 306
+ ++ + L ++ D ++ E + + +++++ QK+ +L T L + K
Sbjct: 1432 MLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTEL-FKVKNV 1490
Query: 307 ESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVE 360
E L + EN+ Q EI L + ++++ ++K+ K + E+ E++
Sbjct: 1491 YEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQ 1544
Score = 48.9 bits (115), Expect = 1e-05
Identities = 81/377 (21%), Positives = 160/377 (42%), Gaps = 56/377 (14%)
Query: 25 DESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKD------- 77
+E +A+ +L +A EV + R KY + + E+ KKK + ++
Sbjct: 1351 EEEQEGKAELQRALSKANSEVAQW-RTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEA 1409
Query: 78 IMSVLSYLKKQDQEKDNMIEKLKQQLNETK------EKAQEEKDKLEQKYTRQINELEGQ 131
+ + + L+K Q N +E L + + +K Q DK+ ++ ++ E + +
Sbjct: 1410 VNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAE 1469
Query: 132 FHQKAKEIGMIHTELKAVRQFQKRKI-----------QVERELDDLKENL-RNTERIHQE 179
KE + TEL V+ + + +++E+ DL E + ++IH+
Sbjct: 1470 LEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHE- 1528
Query: 180 TLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYH 239
L +++ + +EK ++ E+ A H E + N K + + +A
Sbjct: 1529 -LEKIKKQVEQEKCEIQAALEE---AEASLEHEEGKILRIQLELNQVKSE--VDRKIAEK 1582
Query: 240 LKETDALQKNSQKLQES--HTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLET 297
+E D L++N ++ E+ TL + ND L +K M+ +IQ + E+
Sbjct: 1583 DEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAES 1642
Query: 298 ALSY-----MTKEFE---------SEVLKLQQHAMIENQAG--QVEIDKLQHLLQMKDRE 341
+Y + KE + E LK +Q A++E +A Q EI++L L+ +R
Sbjct: 1643 LRNYRNTQGILKETQLHLDDALRGQEDLK-EQLAIVERRANLLQAEIEELWATLEQTERS 1701
Query: 342 MNRVKKLAKNILDERTE 358
+K+A+ L + +E
Sbjct: 1702 ----RKIAEQELLDASE 1714
Score = 46.2 bits (108), Expect = 7e-05
Identities = 53/249 (21%), Positives = 115/249 (46%), Gaps = 23/249 (9%)
Query: 38 LWEARLEVTELSR-------IKYRDTSRILAKSNEDLKKKQCKMEKDIMSVLSYLKKQDQ 90
LW A LE TE SR + + ++L N L + K+E D+ + S +++ Q
Sbjct: 1691 LW-ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQ 1749
Query: 91 EKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEI--GMIHTELKA 148
E N EK K+ + + A+E K EQ + + ++ Q K++ + E A
Sbjct: 1750 ESRNAEEKAKKAITDAAMMAEELKK--EQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLA 1807
Query: 149 VRQFQKRKIQVERELDDLKENLRNTERIHQET---LRRLESRFFEEKHRLEQEAEKKIIM 205
++ +K+ ++E + +L+ + N ++ + E LR+ E R E ++ E++ K ++
Sbjct: 1808 LKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEED-RKNVLR 1866
Query: 206 LAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKE 265
L + + +L ++ ++ + ++ +L + LQ ++ +E + + +
Sbjct: 1867 L-----QDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIA--ESQ 1919
Query: 266 INDLLVKEK 274
+N L VK +
Sbjct: 1920 VNKLRVKSR 1928
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 70.9 bits (172), Expect = 3e-12
Identities = 99/447 (22%), Positives = 200/447 (44%), Gaps = 67/447 (14%)
Query: 3 SKGKDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWE-ARLEVTELSRI--KYRDTSRI 59
++GK +K ++ + +KL + E + + K A WE E +L++ K + I
Sbjct: 1633 AEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNI 1692
Query: 60 LAKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQ 119
LA+ E+L +++ ++ + L++ + + + + K +++LN+ + K EEK KL +
Sbjct: 1693 LAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWK-EEELNQEEGKLVEEKKKLAE 1751
Query: 120 KYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQE 179
E E Q+ K + E + Q ++ IQ + +L KE + E E
Sbjct: 1752 -------EEEALAWQREK----LSEEETKLAQEEELLIQEKEKLAQHKEKMPEEE----E 1796
Query: 180 TLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYH 239
L R + E+K +L Q+ E+ I + E ++ I+ Y +K LA
Sbjct: 1797 RLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMIL--------------YQKKNLA-- 1840
Query: 240 LKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETAL 299
+E L + +KL + LL+ KE + QLVQ ++++ K + +E L
Sbjct: 1841 -QEKKNLAQEKEKLAQRKENLLYNKE----RLTHSKKQLVQVKNKLGMFNKILAQVEEKL 1895
Query: 300 SYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEV 359
T+E E+ + K ++ A E + L+Q++D + +KLA+ + + +
Sbjct: 1896 ---TQEKETVIKKKEKLAETEKK-----------LVQVEDSLAKKQEKLAQEKM--KLAL 1939
Query: 360 ERFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAACTGRTEYPKIRTFDGREHSTNSV 419
E+ + +++ ++ I+++ + A NL+M+ R K+R +G+E +
Sbjct: 1940 EKAMVQGKKRLRGELDIAKE------EKALNLEMK-----RLAEEKMRLVEGKETLSKGE 1988
Query: 420 NQDLLEAEKWTHIEGNVDIGDLTWEQK 446
+ K T +E + L+ E+K
Sbjct: 1989 TPETSRQRKMTQVEQELFERKLSLEEK 2015
Score = 55.5 bits (132), Expect = 1e-07
Identities = 66/327 (20%), Positives = 143/327 (43%), Gaps = 58/327 (17%)
Query: 9 KKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRI--------- 59
KK +S K+ KL K +++ + L + +++T++ R + R+
Sbjct: 2061 KKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDI 2120
Query: 60 -----------LAKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKE 108
L K + L +KQ K+ + +++ +K +E+ + K + + + +E
Sbjct: 2121 KEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEE 2180
Query: 109 KA--QEEK------------------DKLEQKYTRQINELEGQFHQKAKEIGMIHTELKA 148
+ +EE+ DK ++K++ Q++E+E + H ++E+ + EL+
Sbjct: 2181 EGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHF-SEEMESLLDELE- 2238
Query: 149 VRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAE 208
++ + E E + +E R E + +E R E EEK ++E EKK
Sbjct: 2239 ----KQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKK------ 2288
Query: 209 RAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEIND 268
+ E + VF+E + + +ET++L ++ +ES +L +
Sbjct: 2289 KKKKEKKKEEVQEKEEVFEEKEEIMSE-----EETESLSDEEEE-EESCSLEEEVDREKE 2342
Query: 269 LLVKEKIMQLVQQRSQIQTLQKKVVNL 295
+L KEK +L +QR + +++V+++
Sbjct: 2343 ILKKEKQFKLQEQRRKSLRGRERVLSI 2369
Score = 52.4 bits (124), Expect = 1e-06
Identities = 95/449 (21%), Positives = 184/449 (40%), Gaps = 74/449 (16%)
Query: 6 KDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIK------------- 52
K++K GK K + TK+ E V + A + + ++ + R
Sbjct: 1409 KERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWK 1468
Query: 53 --YRDTSRILAKSNEDLKKKQCKMEKDIMSVLSYLKKQDQ----EKDNMIEKLKQ---QL 103
+ +T + E+ +K+ + E+ + L +++ +K E+ KQ +
Sbjct: 1469 QVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENM 1528
Query: 104 NETKEKAQEEKDK----LEQKYTRQINELEGQFHQKAKEIGMIHTELKAVR---QFQKRK 156
+K K Q+ KD+ LE++ +R+ E E Q ++ + I H + R + +K++
Sbjct: 1529 LSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKR 1588
Query: 157 IQVERELDDLKENLRNTERIHQETLRRLESRFFE------EKHRLEQEAEKKIIMLAERA 210
Q ER+L +E L ER + R+L + + E + E + +K LA+R
Sbjct: 1589 AQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRG 1648
Query: 211 HHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLL------LHQK 264
+L+ + ++ L K +E + L K KL E +L L Q+
Sbjct: 1649 E-----KLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQR 1703
Query: 265 EIN-DLLVKE-----------------KIMQLVQQRSQIQTLQKKVVNLETALSYMTKEF 306
E N D KE K +L Q+ ++ +KK+ E AL++ ++
Sbjct: 1704 EQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKL 1763
Query: 307 ESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEV----ERF 362
E KL Q + Q E +KL + E R+ + + +++++ ++ ER+
Sbjct: 1764 SEEETKLAQEEELLIQ----EKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERW 1819
Query: 363 FLDALHQVKQQILISRKHYKQIAQAAFNL 391
K ++++ +K K +AQ NL
Sbjct: 1820 INSMEELTKNKMILYQK--KNLAQEKKNL 1846
Score = 46.6 bits (109), Expect = 6e-05
Identities = 81/390 (20%), Positives = 168/390 (43%), Gaps = 60/390 (15%)
Query: 6 KDKKKGKSKGK---DTKKLIKTDESVV-DRAKANAS----LWEARLEVTELSRI-----K 52
K+++ + +GK + KKL + +E++ R K + E L + E ++ K
Sbjct: 1731 KEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEK 1790
Query: 53 YRDTSRILAKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQE 112
+ L + E L +K+ K+ + ++ + ++ K+ MI K+ L + K+ +
Sbjct: 1791 MPEEEERLGRKREQLIEKKMKLAQKRERWINSM--EELTKNKMILYQKKNLAQEKKNLAQ 1848
Query: 113 EKDKLEQKYTRQINELEGQFHQKAK------EIGMIH-----------TELKAVRQFQKR 155
EK+KL Q+ + E H K + ++GM + E + V + +++
Sbjct: 1849 EKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEK 1908
Query: 156 KIQVERELDDLKENL-RNTERIHQETLR-RLESRFFEEKHRLEQEAEKKIIMLAERAHHE 213
+ E++L ++++L + E++ QE ++ LE + K RL E + I E+A +
Sbjct: 1909 LAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELD---IAKEEKALNL 1965
Query: 214 AIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQ--------KLQESHTLLLHQKE 265
+ +L + + + + L K ET +K +Q KL +LLH+
Sbjct: 1966 EMKRLAEEKMRLVEGKETLSKG---ETPETSRQRKMTQVEQELFERKLSLEEKILLHEDR 2022
Query: 266 I----NDLLVKEKI------MQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQ 315
I + K K+ VQ + ++ +K++ +LS + + LQ+
Sbjct: 2023 ILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQK 2082
Query: 316 HAMIENQAGQVEI--DKLQHLLQMKDREMN 343
E + Q EI K++ L +K+R ++
Sbjct: 2083 LTRDERKLTQEEIKMTKMKRALFVKERRLS 2112
Score = 34.3 bits (77), Expect = 0.29
Identities = 35/176 (19%), Positives = 82/176 (46%), Gaps = 11/176 (6%)
Query: 4 KGKDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKS 63
K K+ K+G + + ES ++ SL + + LS + + +
Sbjct: 2199 KRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEERE 2258
Query: 64 NEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKL---EQK 120
E++++++ + +++ ++K+++EK ++ K++ + KE+ EEK+++ E+
Sbjct: 2259 EEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEET 2318
Query: 121 YTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERI 176
+ E E + +E+ LK +QF K+Q +R +++LR ER+
Sbjct: 2319 ESLSDEEEEEESCSLEEEVDREKEILKKEKQF---KLQEQR-----RKSLRGRERV 2366
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 70.5 bits (171), Expect = 4e-12
Identities = 80/338 (23%), Positives = 155/338 (45%), Gaps = 45/338 (13%)
Query: 65 EDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKA-QEEKDKLEQKYTR 123
E+L ++ + K ++ + L KQ E D++I KLKQ LN+ K++ Q E DK++ T+
Sbjct: 498 EELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMD--ITK 555
Query: 124 QINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRR 183
+++ + + Q + +H QK + +VE +D L ++ + I +E L
Sbjct: 556 ELDVQKEKLIQSEVALNDLHLTK------QKLEDKVENLVDQLNKSQESNVSIQKENL-- 607
Query: 184 LESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLN-DAGRN----VFKENDYLQKALAY 238
E K + Q E+ R +E + LN D+ N + KE + + L
Sbjct: 608 ------ELKEHIRQNEEE-----LSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQ 656
Query: 239 HLKETDALQKNSQKL-----QESHTLLLH----QKEINDLLVKEKIMQLVQQRSQIQTLQ 289
+L E + L +N +K+ E+ L+L + ++ + L + L ++ + ++TL+
Sbjct: 657 NLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSL-EKNTIVETLK 715
Query: 290 KKVVNLETALSYMTK-------EFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREM 342
+ +E L + K ++E + +L + A Q+E + L L Q KD E+
Sbjct: 716 MEKGEIEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEI 775
Query: 343 NRVKKLAKNILDERTEVERFFLDALHQVKQQI-LISRK 379
+KK + + + E + +L + KQ LI++K
Sbjct: 776 AELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKK 813
Score = 64.3 bits (155), Expect = 3e-10
Identities = 86/387 (22%), Positives = 168/387 (43%), Gaps = 45/387 (11%)
Query: 13 SKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKK-- 70
S KDT L+K E+ V K N S E E + + + L + ED++ +
Sbjct: 637 SNFKDT--LLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLE 694
Query: 71 QCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETK-EKAQEEKDKLEQ--KYTRQINE 127
+C + +S+ EK+ ++E LK + E + E +K LE+ KY + I E
Sbjct: 695 ECLAGNNQLSL---------EKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEE 745
Query: 128 LEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESR 187
L + + + H L + Q + + E+ +LK+N+ + H+ET L S
Sbjct: 746 LSNARNLNTSALQLEHEHLIKLNQ------KKDMEIAELKKNIEQMDTDHKETKDVLSSS 799
Query: 188 FFEEKHRLEQEAEKKIIMLAERAHHEAIVQLN-DAGRNVFKENDYLQKALAYHLKETDAL 246
EE+ +L Q KK I + + + +Q D ++N+ L++ + + ++
Sbjct: 800 -LEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSM 858
Query: 247 QKNSQKLQESHTLLLHQKE----INDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYM 302
++ + LQE L ++ + D + + +L + SQ+ T+++ +LE + +
Sbjct: 859 KEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKE---HLEEEIKHH 915
Query: 303 TKEFESE-VLKLQQHAMIENQAGQVEIDKLQH---------LLQMKDREMNRVKKLAKNI 352
K E + K+Q ++ Q +++ + QH L KD E+ ++K + I
Sbjct: 916 QKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQI 975
Query: 353 L----DERTEVERFFLDALHQVKQQIL 375
+ER +++ D + K Q L
Sbjct: 976 KTQLHEERQDIQTDNSDIFQETKVQSL 1002
Score = 63.2 bits (152), Expect = 6e-10
Identities = 89/428 (20%), Positives = 186/428 (43%), Gaps = 62/428 (14%)
Query: 37 SLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMI 96
S+ E EV++L+ IK E++K Q +E S + L+ ++K M
Sbjct: 890 SVTELASEVSQLNTIKEH--------LEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMD 941
Query: 97 EKLKQ--QLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQK 154
E Q Q+N T + EKD+ + + I +++ Q H++ ++I ++++ + Q
Sbjct: 942 EFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQS 1001
Query: 155 RKIQVERELDDLKENLRNTERIHQETL-RRLESRFFEEKH--------RLEQEAEKKIIM 205
I+ E DL + TER+ + R LE + EK+ +L ++ K+
Sbjct: 1002 LNIENGSEKHDLSK--AETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDEVGKLTQ 1059
Query: 206 LAERAHHE-AIVQLNDAGRNVFKENDYLQKAL-AYHLKETDALQKNSQKLQE-SHTLLLH 262
+ ++ E + + + ++ YLQ+ L AY ++ ++K +E SH +
Sbjct: 1060 IIQQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEY 1119
Query: 263 QKEINDLLVKEKIMQLVQQ-----------------RSQIQTLQKKVVNLETALSYMTKE 305
K ++ + KE + +Q R IQ L + + + + ++++
Sbjct: 1120 HKMMDIVAAKEAALIKLQDENKKLSTRFESSGQDMFRETIQNLSRIIREKDIEIDALSQK 1179
Query: 306 FESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVERF--- 362
++ +L + Q + N+AG V ++ + LLQ +D+ +VKK+ + T V+
Sbjct: 1180 CQT-LLAVLQTSSTGNEAGGVNSNQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHE 1238
Query: 363 ---FLDALHQVKQQILISRKHYKQIAQAAFNLKMRAACTGRTEYPKIRTFDGREHSTNSV 419
+ LHQ++ Q+L+ + N K++ TG I++++ E +
Sbjct: 1239 SAQLQEELHQLQAQVLVDSDN---------NSKLQVDYTG-----LIQSYEQNETKLKNF 1284
Query: 420 NQDLLEAE 427
Q+L + +
Sbjct: 1285 GQELAQVQ 1292
Score = 48.5 bits (114), Expect = 1e-05
Identities = 66/348 (18%), Positives = 157/348 (45%), Gaps = 76/348 (21%)
Query: 94 NMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELE-------GQFHQKAKEI------- 139
N+I++LKQ ++ + Q E L+ + +++ E+ + ++ +E+
Sbjct: 216 NIIKELKQNRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDYEERIEELENLLQQG 275
Query: 140 --GMIHTELKAVRQFQ--------------KRKIQVERELDDLKENLRNTERIHQETLRR 183
G+I T+L + + Q K+ Q+E ++ D+ + L + E ++ LRR
Sbjct: 276 GSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAEN-DRDILRR 334
Query: 184 LESRFFEEKHRLEQEAE---------------------KKIIMLAERAHHEAIVQLNDAG 222
+ + EK ++ +E E +K +LA+ A E + +L A
Sbjct: 335 EQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQAL 394
Query: 223 RNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQR 282
+ EN+ ++ + L + ++L +++ KL+ +L +K + +E M L++
Sbjct: 395 SDA--ENEIMRLS---SLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLN 449
Query: 283 SQIQTLQK---KVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKL-------- 331
++ + ++ + ++L++ L + E++ +L Q ++ E + EI++L
Sbjct: 450 NEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQ-SISEKETLIAEIEELDRQNQEAT 508
Query: 332 QHLLQMKD---REMNR----VKKLAKNILDERTEVERFFLDALHQVKQ 372
+H++ +KD ++ N + KL +++ DE+ V + D + K+
Sbjct: 509 KHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKE 556
Score = 45.1 bits (105), Expect = 2e-04
Identities = 78/358 (21%), Positives = 149/358 (41%), Gaps = 38/358 (10%)
Query: 20 KLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDIM 79
+L+ ++E+ ++ N L +A + E I D ++ + NE + + E +
Sbjct: 1422 QLLSSNENFTNKVNENELLRQAVTNLKERILILEMDIGKLKGE-NEKIVETYRGKETEYQ 1480
Query: 80 SVLSYLKKQDQEKDNMIEKLKQQLNETKEKA----QEEKDKLEQKYTRQINELEGQFHQK 135
+ L++ + + M+ + + + + KEKA Q K+K EQ T ++N+L
Sbjct: 1481 A----LQETNMKFSMMLREKEFECHSMKEKALAFEQLLKEK-EQGKTGELNQLLNAVKSM 1535
Query: 136 AKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRL 195
++ + E V K+K L + + LR+ E + L RL + E +
Sbjct: 1536 QEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELERLRNHLLESEDSY 1595
Query: 196 EQEA----------EKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETD- 244
+EA KK+ +L E+ + + +A + + LQ+ L K+ D
Sbjct: 1596 TREALAAEDREAKLRKKVTVLEEKLVSSSNA-MENASHQASVQVESLQEQLNVVSKQRDE 1654
Query: 245 -ALQKN-SQKLQESHTLLLH--QKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALS 300
ALQ + SQ+ + + L L Q + +EK M + Q Q + + N E
Sbjct: 1655 TALQLSVSQEQVKQYALSLANLQMVLEHFQQEEKAMYSAELEKQKQLIAEWKKNAE---- 1710
Query: 301 YMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKD---REMNRVKKLAKNILDE 355
E +V+ LQ+ + E A +L L +K+ E+ R +L + +LD+
Sbjct: 1711 ----NLEGKVISLQE-CLDEANAALDSASRLTEQLDVKEEQIEELKRQNELRQEMLDD 1763
Score = 43.5 bits (101), Expect = 5e-04
Identities = 65/334 (19%), Positives = 147/334 (44%), Gaps = 29/334 (8%)
Query: 100 KQQLNE-TKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQ 158
+Q++N + E ++ E + ++ Q ++ +G + EI + +K ++Q + +
Sbjct: 171 QQEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRSQ--- 227
Query: 159 VERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQL 218
E+DD + + + HQ+ L + R EE E+ E+ +L + L
Sbjct: 228 ---EIDDHQHEMSVLQNAHQQKLTEISRRHREELSDYEERIEELENLLQQGGSGVIETDL 284
Query: 219 NDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQL 278
+ +++ +Q ++ T +++ K+++ + L + D+L +E+
Sbjct: 285 S----KIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLN 340
Query: 279 VQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMK 338
V++R ++ + + LE + + +S+ + ++ ++ A E+ +LQ L
Sbjct: 341 VEKRQIMEECEN--LKLECSKLQPSAVKQSDTM-TEKERILAQSASVEEVFRLQQALSDA 397
Query: 339 DREMNRVKKLAK-NILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAAC 397
+ E+ R+ L + N L E D L ++K +I + K ++Q L+M +
Sbjct: 398 ENEIMRLSSLNQDNSLAE---------DNL-KLKMRIEVLEKEKSLLSQEKEELQM-SLL 446
Query: 398 TGRTEYPKIRTFDGREHSTNSVNQDL---LEAEK 428
EY I++ R+ S +S DL LEA++
Sbjct: 447 KLNNEYEVIKSTATRDISLDSELHDLRLNLEAKE 480
Score = 42.0 bits (97), Expect = 0.001
Identities = 76/364 (20%), Positives = 159/364 (43%), Gaps = 49/364 (13%)
Query: 36 ASLWEARLEVTELSRIKYRDTSRILAKSN---EDLKKKQCKMEKDIMSVLSYLKKQDQEK 92
AS E E +EL + + + + L + + L++ ++ I + +K+ ++
Sbjct: 1332 ASKSEVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQT 1391
Query: 93 DNMIEKLKQQLNETKEKAQEEKDKL-----------EQKYTRQINELE--GQFHQKAKE- 138
D+ I++LK++ + +K +EKD L + +T ++NE E Q KE
Sbjct: 1392 DSEIKQLKEK-QDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKER 1450
Query: 139 IGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQE 198
I ++ ++ ++ ++ ++ R + + L+ T LR E E H ++++
Sbjct: 1451 ILILEMDIGKLKGENEKIVETYRGKETEYQALQETNMKFSMMLREKEF----ECHSMKEK 1506
Query: 199 --AEKKIIMLAERAHHEAIVQLNDAGRN------VF-KENDYLQKALAYHLKETDALQKN 249
A ++++ E+ + QL +A ++ VF +E D + AL E ALQ
Sbjct: 1507 ALAFEQLLKEKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNE 1566
Query: 250 SQKL--------QESHTLLLHQKEINDLLVKEKIM---QLVQQRSQIQTLQKKVVNLETA 298
Q+L QE L H E D +E + + + R ++ L++K+V+ A
Sbjct: 1567 VQRLRDKEFRSNQELERLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNA 1626
Query: 299 LSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTE 358
+ + + +V LQ+ Q V + + LQ+ + +VK+ A ++ + +
Sbjct: 1627 MENASHQASVQVESLQE------QLNVVSKQRDETALQLSVSQ-EQVKQYALSLANLQMV 1679
Query: 359 VERF 362
+E F
Sbjct: 1680 LEHF 1683
Score = 41.2 bits (95), Expect = 0.002
Identities = 75/389 (19%), Positives = 159/389 (40%), Gaps = 36/389 (9%)
Query: 33 KANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEK 92
+ A L ++R + E R + L K DL++K E I + + Q Q+K
Sbjct: 44 EVEAELPDSRTKEIEAIHAILRSENERLKKLCTDLEEKHEASEIQIKQQSTSYRNQLQQK 103
Query: 93 DNMIEKLK-------QQLNETKEKAQE-------EKDKLEQKYTRQINELEGQFHQKAKE 138
+ I LK QL + + AQ + I+ FH +
Sbjct: 104 EVEISHLKARQIALQDQLLKLQSAAQSVPSGAGVPATTASSSFAYGISHHPSAFHDDDMD 163
Query: 139 IGMIHTELKAVRQFQKRKIQVERELDDLK-----ENLRNTERIHQETLRRLESRFFEEKH 193
G I + + + + ++E E+ + + T+ Q + +L++ E K
Sbjct: 164 FGDIISSQQEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQ 223
Query: 194 RLEQEAE--KKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKE--TDALQKN 249
QE + + + + + AH + + +++ R + + + L L++ + ++ +
Sbjct: 224 NRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDYEERIEELENLLQQGGSGVIETD 283
Query: 250 SQKLQESHTLLLHQKEINDLLVK--EKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFE 307
K+ E QK I L ++ E ++ Q +I+ + KK+ + E + +E E
Sbjct: 284 LSKIYEM------QKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQE 337
Query: 308 SEVLKLQQHAMIENQAGQVEIDKLQ-HLLQMKDREMNRVKKLAKNI-LDERTEVERFFLD 365
++ +Q M E + ++E KLQ ++ D + + LA++ ++E +++ D
Sbjct: 338 QLNVEKRQ-IMEECENLKLECSKLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQALSD 396
Query: 366 ALHQVKQQILISRKHYKQIAQAAFNLKMR 394
A +++ + L S +A+ LKMR
Sbjct: 397 AENEIMR--LSSLNQDNSLAEDNLKLKMR 423
Score = 30.0 bits (66), Expect = 5.5
Identities = 33/165 (20%), Positives = 72/165 (43%), Gaps = 25/165 (15%)
Query: 67 LKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLE------QK 120
L+KK +E+ ++S + ++ + +E L++QLN ++ E +L ++
Sbjct: 1609 LRKKVTVLEEKLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQ 1668
Query: 121 YTRQINELEGQF-HQKAKEIGMIHTELKAVRQ-----------FQKRKIQVERELDDLKE 168
Y + L+ H + +E M EL+ +Q + + I ++ LD+
Sbjct: 1669 YALSLANLQMVLEHFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEANA 1728
Query: 169 NLRNTER------IHQETLRRLESRFFEEKHRLEQEAEKKIIMLA 207
L + R + +E + L+ R E + + + +KK++ LA
Sbjct: 1729 ALDSASRLTEQLDVKEEQIEELK-RQNELRQEMLDDVQKKLMSLA 1772
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 70.1 bits (170), Expect = 5e-12
Identities = 90/400 (22%), Positives = 175/400 (43%), Gaps = 67/400 (16%)
Query: 52 KYRDTSRILAKSNEDLKK-KQCKMEK---------DIMSVLSYLKKQDQEKDNMIEKLKQ 101
K +T R L +++ LK+ +Q EK D+ LS L++Q +EK +L+
Sbjct: 422 KLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQH 481
Query: 102 QLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGM-------------------- 141
QL++TK++ QE++ L+Q T ++ E + Q ++IG
Sbjct: 482 QLDKTKQQHQEQQ-ALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENIS 540
Query: 142 --------IHTELKA-------VRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLES 186
++ +++A + Q Q++ ++ ++ L E L+N H++ L
Sbjct: 541 LLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHD 600
Query: 187 RFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDAL 246
+ E+K L + A+ +++ L E + +E QLN++ V + D KA L +A
Sbjct: 601 QVQEQKAHL-RAAQDRVLSL-ETSVNELNSQLNESKEKV-SQLDIQIKAKTELLLSAEAA 657
Query: 247 QKNSQKLQESH------TLLLHQKEINDLL-----VKEKIMQLVQQRSQIQTLQKKVVNL 295
+ + ++H L Q+E+N + V K+ + SQ+++ K+
Sbjct: 658 KTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEK 717
Query: 296 ETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDE 355
+L T+E E ++ KL+ ++ + + + LQ Q+ R +L+K + E
Sbjct: 718 YLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEME 777
Query: 356 RTEVERFFLD------ALHQVKQQILISRKHYKQIAQAAF 389
+ V LD AL +KQ+ L ++ KQI + F
Sbjct: 778 KEIVSSTRLDLQKKSEALESIKQK-LTKQEEEKQILKQDF 816
Score = 66.6 bits (161), Expect = 5e-11
Identities = 98/412 (23%), Positives = 182/412 (44%), Gaps = 45/412 (10%)
Query: 14 KGKDTKKLIKTDESVVDR--AKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKK- 70
K K K+ + T+ S V +K + SL ++ E E K + L K+ ++LK +
Sbjct: 843 KVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEF-EKENQKGKAAILDLEKTCKELKHQL 901
Query: 71 QCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEK------AQEEKDKLEQKYTRQ 124
Q +ME + K ++EK+ +LK +LN +E+ ++ +K EQ+
Sbjct: 902 QVQMENTLKEQKELKKSLEKEKEAS-HQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGN 960
Query: 125 INELEGQFHQKAKEIGMIHTELKAV--------RQFQKRKIQVERELDDLKEN---LRNT 173
INEL+ QK K+I + ELK + Q++ Q +EL KE L+N
Sbjct: 961 INELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNN 1020
Query: 174 ERIHQETLRRLESRFFEEKHRL--EQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDY 231
QET ++L+S F+ + L ++ K + A + I N G +N
Sbjct: 1021 YEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIG----NQNKL 1076
Query: 232 LQK-ALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQK 290
+Q+ A E D+ +K Q + L QKE + +KEK +LV ++S++ +++
Sbjct: 1077 IQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKS---LKEK--ELVNEKSKLAEIEE 1131
Query: 291 KVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEID-------KLQHLLQMKDREMN 343
E ++ + +E +S L+ + A Q+ I K L ++E
Sbjct: 1132 IKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKR 1191
Query: 344 RVKKLAKNILDERTEVERFFLD---ALH-QVKQQILISRKHYKQIAQAAFNL 391
+ L + E E+++ F++ LH ++K++ + +KH + A+ +
Sbjct: 1192 NQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQI 1243
Score = 64.3 bits (155), Expect = 3e-10
Identities = 91/389 (23%), Positives = 171/389 (43%), Gaps = 63/389 (16%)
Query: 18 TKKLIKTDESVVDRAKANASLWEARLEVTEL-SRIKYRDTSRILAKSNEDLKKKQCKMEK 76
TK K +E V + A+L + L+ +L SR+ +TS L + + +L +K +K
Sbjct: 319 TKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETS--LHRIHVELSEKGEATQK 376
Query: 77 DIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKA 136
LK++ E + + LK + + +++ +EEK++ + +IN+L + +
Sbjct: 377 --------LKEELSEVETKYQHLKAEFKQLQQQ-REEKEQHGLQLQSEINQLHSKLLETE 427
Query: 137 KEIGMIHTELKAVRQFQKRKI-QVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRL 195
+++G H LK RQ K+ E+++ DL+ L RL
Sbjct: 428 RQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKL----------------------SRL 465
Query: 196 EQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETD--------ALQ 247
E++ ++K+ E H QL D + +E LQ++ L+E +
Sbjct: 466 EEQLKEKVTNSTELQH-----QL-DKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIG 519
Query: 248 KNSQKLQESHTLLLHQKEINDLLVKE------KIMQLVQQRSQIQTLQKKVVNLETALSY 301
QK+Q LL KE LL KE KI + + + LQ+K L+ ++
Sbjct: 520 DKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQ 579
Query: 302 MTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMN---RVKKLAKNILDERTE 358
+T++ +++ +Q EN QV+ K HL +DR ++ V +L + + + +
Sbjct: 580 LTEKLKNQSESHKQAQ--ENLHDQVQEQK-AHLRAAQDRVLSLETSVNELNSQLNESKEK 636
Query: 359 VERFFLDALHQVKQQILISRKHYKQIAQA 387
V + LD + K ++L+S + K +A
Sbjct: 637 VSQ--LDIQIKAKTELLLSAEAAKTAQRA 663
Score = 61.6 bits (148), Expect = 2e-09
Identities = 80/297 (26%), Positives = 129/297 (43%), Gaps = 33/297 (11%)
Query: 70 KQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELE 129
KQ +MEK+I +S + Q+K +E +KQ+L K +EEK L+Q + E +
Sbjct: 772 KQLEMEKEI---VSSTRLDLQKKSEALESIKQKLT----KQEEEKQILKQDFETLSQETK 824
Query: 130 GQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFF 189
Q + I TEL+ V+ K + EL +K+ L ++L+ +S F
Sbjct: 825 IQHEELNNRIQTTVTELQKVKM---EKEALMTELSTVKDKLSKV----SDSLKNSKSEF- 876
Query: 190 EEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKAL-----AYHLKETD 244
EK E + K I+ E+ E QL N KE L+K+L A H + +
Sbjct: 877 -EK---ENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLE 932
Query: 245 ALQKNSQKLQESHTLLLHQKEINDLL--VKEKIMQLVQQRSQIQTLQKKVVNLETALSYM 302
Q +Q +TL ++KE L + E Q++ QI+ LQ + L+ A+
Sbjct: 933 LNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGE---LKIAVLQK 989
Query: 303 TKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEV 359
T E E+ KLQQ Q E +K+ L ++ K+L + +E+
Sbjct: 990 T-ELEN---KLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESEL 1042
Score = 51.6 bits (122), Expect = 2e-06
Identities = 84/412 (20%), Positives = 183/412 (44%), Gaps = 43/412 (10%)
Query: 65 EDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQ 124
+DLK + +++ + ++ LKK+ + +++ + + EK ++E KL+ +Y
Sbjct: 208 QDLKTEL--LQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASS 265
Query: 125 ---INELEGQFHQKAKEIGMIHTELKAVRQ-----FQKRKIQVERELDDLKENLRNTERI 176
I++L + + +E+ + EL+ ++ QK + E L ++ + E+
Sbjct: 266 EATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKH 325
Query: 177 HQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKAL 236
++E++ + + + L+ + + + +E + H V+L++ G K + L +
Sbjct: 326 NEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVE 385
Query: 237 A--YHLKETDALQKNSQKLQESHTLLLHQKEINDLLVK---------EKIMQLVQQR--- 282
HLK + ++ +E H L L Q EIN L K E +L +QR
Sbjct: 386 TKYQHLKAEFKQLQQQREEKEQHGLQL-QSEINQLHSKLLETERQLGEAHGRLKEQRQLS 444
Query: 283 -SQIQTLQKKVVNLETALSYMTKEFESEVLKLQ--QHAMIENQAGQVEIDKLQHLLQMKD 339
++ +++V +L+ LS + ++ + +V QH + + + E LQ K
Sbjct: 445 SEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKL 504
Query: 340 RE-MNRVKKLAKNILDERTEVERFFLDALHQ-VKQQILISRKHYKQIAQAAFNLKMRAAC 397
RE N ++++ + I D+ +++ L+AL Q K+ I + K + + K++A
Sbjct: 505 REAQNDLEQVLRQIGDKDQKIQN--LEALLQKSKENISLLEKEREDL-----YAKIQA-- 555
Query: 398 TGRTEYPKIRTFDGREHS-TNSVNQ--DLLEAEKWTHIEGNVDIGDLTWEQK 446
G E + + H+ V Q + L+ + +H + ++ D EQK
Sbjct: 556 -GEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQK 606
Score = 51.2 bits (121), Expect = 2e-06
Identities = 68/280 (24%), Positives = 115/280 (41%), Gaps = 54/280 (19%)
Query: 23 KTDESVVDRAKA------NASLWEARL-----EVTELSRIKYRDTSRILAKSNEDLKKKQ 71
K ++ + +R KA SL E L ++ E+ IK R I K NE+LK +
Sbjct: 1093 KKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEI-TKLNEELKSHK 1151
Query: 72 CKMEKDIMSVLS---YLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKL---EQKYTRQI 125
+ K+I ++ L +Q E + LK + + K Q KD++ E++ ++
Sbjct: 1152 LESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEF 1211
Query: 126 NELEGQFHQ--KAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRR 183
E E + H K KE+GM ++ ++ + ++ ++ L ENL ++ Q + RR
Sbjct: 1212 IEKEAKLHSEIKEKEVGM--------KKHEENEAKLTMQITALNENLGTVKKEWQSSQRR 1263
Query: 184 LESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDY------------ 231
+ LE++ + + E A EA VQ N R E
Sbjct: 1264 VSE--------LEKQTDD---LRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTK 1312
Query: 232 ---LQKALAYHLKETDALQKNSQKLQESHTLLLHQKEIND 268
LQ+ L L + +Q LQ HT L++K D
Sbjct: 1313 VLELQRKLDNTTAAVQELGRENQSLQIKHTQALNRKWAED 1352
Score = 45.8 bits (107), Expect = 1e-04
Identities = 64/326 (19%), Positives = 149/326 (45%), Gaps = 23/326 (7%)
Query: 53 YRDTSRILAKSNEDLKKKQCKM---EKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEK 109
Y S +LA + +DLK + K+ ++D++S + + Q+ KL Q+L K
Sbjct: 1036 YGRESELLA-TRQDLKSVEEKLSLAQEDLISNRNQIGNQN--------KLIQELKTAKAT 1086
Query: 110 AQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKEN 169
+++ K EQ+ + L+ +K+ + + E + + ++ K + E+E+ L E
Sbjct: 1087 LEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEE 1146
Query: 170 LRN--TERIHQET-LRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVF 226
L++ E I + T L+ + ++K L+ +A+ + + ++ I++
Sbjct: 1147 LKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEE 1206
Query: 227 KENDYLQKALAYH--LKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQ 284
+ ++++K H +KE + K ++ + T+ + N VK K Q Q+R
Sbjct: 1207 LKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVK-KEWQSSQRR-- 1263
Query: 285 IQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIEN-QAGQVEIDKLQHLLQMKDREMN 343
+ L+K+ +L ++ + ++ + ++ A++E G+ EI+KLQ + R+++
Sbjct: 1264 VSELEKQTDDLRGEIAVLEATVQNN--QDERRALLERCLKGEGEIEKLQTKVLELQRKLD 1321
Query: 344 RVKKLAKNILDERTEVERFFLDALHQ 369
+ + E ++ AL++
Sbjct: 1322 NTTAAVQELGRENQSLQIKHTQALNR 1347
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 69.7 bits (169), Expect = 6e-12
Identities = 92/407 (22%), Positives = 182/407 (44%), Gaps = 56/407 (13%)
Query: 13 SKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQC 72
SK ++ ++ E + K+N +L E YR S+ + +K++
Sbjct: 389 SKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELS 448
Query: 73 KMEKDIMSV---LSYLKKQDQEKDNMIEKLKQQLNETKEKAQ-------------EEKDK 116
+ + +++++ L L Q + IE LK+ L +++A EEK+
Sbjct: 449 RKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKET 508
Query: 117 LEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQV-ERELDDLKENLRNTER 175
+ K T+QI ++ +K + G IH +LK + ++RK+ V ++++++L+E LR+ E+
Sbjct: 509 MLNKKTKQIQDMA---EEKGTQAGEIH-DLKDMLDVKERKVNVLQKKIENLQEQLRDKEK 564
Query: 176 IHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKA 235
R++S +A+ A EA+ + + ++ D ++
Sbjct: 565 QMSSLKERVKS----------LQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDERE 614
Query: 236 LAYHLKETDALQKNSQKLQESHTLL---LHQKEINDLLVKEKIMQLVQQRSQIQTLQKKV 292
+E D +K+ + L+E +LL L +KE + L +KE L S ++
Sbjct: 615 ---KQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLA---SSGLKKDSRL 668
Query: 293 VNLETALSYMTKE---FESEVLKLQQHAMIENQAGQVEIDKLQHL----LQMKDR----- 340
LE AL +E ES+ LK A +E +A D++QHL + KD
Sbjct: 669 KTLEIALEQKKEECLKMESQ-LKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQ 727
Query: 341 -EMNRVKKLAKNILDERTEVERFFLDALHQVKQQ--ILISRKHYKQI 384
E++R+ ++ K + +E+ + ++ + QVK Q + + KH +Q+
Sbjct: 728 AEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQV 774
Score = 61.2 bits (147), Expect = 2e-09
Identities = 80/350 (22%), Positives = 158/350 (45%), Gaps = 53/350 (15%)
Query: 13 SKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQC 72
S G +KT E +++ K E S++K + + A+++ ++ +
Sbjct: 659 SSGLKKDSRLKTLEIALEQKKEECLKME--------SQLKKAHEAALEARASPEMSDRIQ 710
Query: 73 KMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQF 132
+E++I K E D ++E LK+ NE + +KDK +I ELE Q
Sbjct: 711 HLEREITRYKDESSKAQAEVDRLLEILKEVENE-----KNDKDK-------KIAELERQV 758
Query: 133 HQKAKEIGMIHTELKAVRQFQKRK-IQVERELDDLKENLRNTERIHQETLRRLESRFFEE 191
+ K++ LK Q +K+K Q+ E ++NL ++ + Q++LR+ + R E
Sbjct: 759 KDQNKKVA----NLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEE- 813
Query: 192 KHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQ 251
LE+ + + + AER + Q A N K+ + L A+ +E ++++
Sbjct: 814 ---LEEALRESVQITAER--EMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS 868
Query: 252 KLQESHTLLLHQKEINDLLVK-----EKIMQLVQQRSQIQTLQKKVVNLETA-LSYMTKE 305
Q+S L + + +L + E+++++ +Q + + + +K N+ LS K+
Sbjct: 869 STQQS--LAEKETHLTNLRAERRKHLEEVLEM-KQEALLAAISEKDANIALLELSSSKKK 925
Query: 306 FESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDE 355
+ EV L++ E D+L + Q+K + NR+K +A N D+
Sbjct: 926 TQEEVAALKR-----------EKDRL--VQQLKQQTQNRMKLMADNYEDD 962
Score = 48.9 bits (115), Expect = 1e-05
Identities = 74/364 (20%), Positives = 151/364 (41%), Gaps = 63/364 (17%)
Query: 40 EARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDIMSV---LSYLKKQDQEKDNMI 96
E ++ V + ++ R K LK++ ++ D + L+ L++ EK+ I
Sbjct: 542 ERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTI 601
Query: 97 EKLKQQLNETKEKAQEEKDKLE---QKYTRQINELEGQFHQKAKEI--------GMIHTE 145
E+LK+Q + + + QEE D + + +++ L+G +K + + +
Sbjct: 602 ERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSG 661
Query: 146 LKAVRQFQKRKIQVERELDDLKENLRNTERIHQ---------------ETLRRLESRFFE 190
LK + + +I +E++ ++ + ++ H+ + L R +R+ +
Sbjct: 662 LKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKD 721
Query: 191 EKHRLEQEAEKKIIMLAERAHH---------EAIVQLNDAGRNV--FKENDYLQKALAYH 239
E + + E ++ + +L E + E Q+ D + V K + ++K +
Sbjct: 722 ESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQ 781
Query: 240 LKE-----TDALQKNSQKLQESHTLLLHQKEINDL---------LVKEKIMQLVQQRSQI 285
+ E D L +SQ+LQ+S L I +L + E+ M L Q+ S
Sbjct: 782 MLEEARRREDNLNDSSQQLQDS--LRKKDDRIEELEEALRESVQITAEREMVLAQEESAR 839
Query: 286 QTLQKKVVNLETALSYMTKEFESEVLKL----QQHAMIENQAGQVEIDKLQHL---LQMK 338
+K+V L A+ + +E ES KL Q A E + ++ +HL L+MK
Sbjct: 840 TNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMK 899
Query: 339 DREM 342
+
Sbjct: 900 QEAL 903
Score = 39.3 bits (90), Expect = 0.009
Identities = 57/275 (20%), Positives = 122/275 (44%), Gaps = 24/275 (8%)
Query: 90 QEKDNMIEKLKQQLNET---KEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTEL 146
Q +DN I L+ QL E + +++ + E K + +N ++ + + K+
Sbjct: 145 QARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKE------- 197
Query: 147 KAVRQFQKRKIQVERE----LDDLKENLRNTERIHQETLR--RLESRFFEEKHRLEQEAE 200
+A+R+ + KI + +E + + ++++ T + Q+ LR R ++ F++ + E
Sbjct: 198 RALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSS-SRTGE 256
Query: 201 KKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLL 260
+ L E E +L+ KE L+K L + ++ ES L
Sbjct: 257 PCVAELTE----ENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKL 312
Query: 261 LHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIE 320
L + L K + R ++ + V +LE+ L KE E+ +L+ + H E
Sbjct: 313 LEMLQSKGLSAKATEEDHERTR-RLAEAEMHVHHLESLLEQ--KEKENSMLREEMHRRFE 369
Query: 321 NQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDE 355
N + LQ +++MKD +++ +++ +++ +E
Sbjct: 370 NAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEE 404
>gi|118918423 hypothetical protein LOC286207 [Homo sapiens]
Length = 520
Score = 69.3 bits (168), Expect = 8e-12
Identities = 72/373 (19%), Positives = 166/373 (44%), Gaps = 19/373 (5%)
Query: 3 SKGKDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAK 62
SK + + K KG + ++ + + AK + ++ E +Y+ LA
Sbjct: 8 SKAGKELEVKKKGGKKEPVVAVEPPL---AKEMKEFYHIQIRDLEDRLARYQRKWDELAV 64
Query: 63 SNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYT 122
+ +++ ++ + ++++LK+ ++ + I L +QL + + EKD E +
Sbjct: 65 QEKMFRQEFEQLANNKKEIVAFLKRTLNQQVDEITDLNEQLQNLQLAKEMEKDAFEAQLA 124
Query: 123 RQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLR 182
+ +E + Q E ++ +L A+ +F+ +K +V + L+E +R E ++
Sbjct: 125 QVRHEFQETKDQLTTENIILGGKLAALEEFRLQKEEVTDKFTLLEEQVRKQENEFRDYAY 184
Query: 183 RLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKE 242
LE + +K RL +E +++ ++A H ++ + + KEN+ + +A ++
Sbjct: 185 NLEKKSVLDKDRLRKEIIQRVNLVANEFHKVTTNRMWETTKRAIKENNGITLQMARVSQQ 244
Query: 243 TDALQKNSQKLQESHTLLLHQKEINDLLVK---------EKIMQLVQQRSQIQTLQKKVV 293
L + +++L+ L Q E+ + K +KI+ ++ ++ Q Q K
Sbjct: 245 GMKLLQENEQLKGRQNNLCKQLELLENTQKVMARHKRGHQKIILMLTKKCQEQQQDTKEA 304
Query: 294 NLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNIL 353
L + + E L+LQ ++NQA + + D+L L+ + ++ R+++ N
Sbjct: 305 E---ELRLLLSQLEQRSLQLQ----VDNQALKSQRDQLSLQLEQQQVDLQRLQQELANEQ 357
Query: 354 DERTEVERFFLDA 366
R +E + A
Sbjct: 358 KVRASLEAALVQA 370
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 66.6 bits (161), Expect = 5e-11
Identities = 74/350 (21%), Positives = 157/350 (44%), Gaps = 34/350 (9%)
Query: 66 DLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLK----QQLNETKEKAQEEKDKLEQKY 121
D ++ Q + E+D + L + +QE +E+ K +++N+ +EK ++E+ +Q+
Sbjct: 816 DTERSQAEQERD--AAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQEL 873
Query: 122 TRQINELEGQFHQKAKEIGMIHTELKAVR-QFQKRKIQVERELDDLKENLRNTERIHQET 180
+ + LE + + + TE++A++ Q ++ + Q E L ++ ET
Sbjct: 874 AKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLET 933
Query: 181 LRRLESRFFEEKHRLEQ-EAEKKIIMLAERAHHEAI-VQLNDAGRNVFKENDYLQKALAY 238
L + + + +LE+ + K+ L E+ + QL +A R L++A
Sbjct: 934 LLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRE-------LKEAARQ 986
Query: 239 HLKETDALQKNSQKLQESHTLLLHQKEINDL------------LVKEKIMQLVQQRSQIQ 286
H + ALQ+ S L + L QK++ DL LV++++ + +++ +
Sbjct: 987 HRDDLAALQEESSSLLQDKMDL--QKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYN 1044
Query: 287 TLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVK 346
+QK++ + +L+ E E +L LQ+ I Q E+ L+ +Q E +
Sbjct: 1045 RIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQ----ELSALRQDMQEAQGEQKELS 1100
Query: 347 KLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAA 396
+ + E E E FL Q+ +++ S +Q+ + + + +AA
Sbjct: 1101 AQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAA 1150
Score = 58.9 bits (141), Expect = 1e-08
Identities = 94/432 (21%), Positives = 188/432 (43%), Gaps = 61/432 (14%)
Query: 19 KKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRI--LAKSNEDLKKKQCKMEK 76
+KLIK E R +L L++ E S+ +S+I L + L ++ + ++
Sbjct: 1573 QKLIKELEG--QRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQ 1630
Query: 77 DIMSVLSYLKKQDQEKDNM---IEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFH 133
++ S +++ ++K+++ +E+ Q+L KE+ Q LE + TRQ LE
Sbjct: 1631 EVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQV----LEDQRTRQTKILEEDLE 1686
Query: 134 QKAKEIGMIHTELKAVRQFQKRKIQVER--------ELDDLKENLRNTERI------HQE 179
Q + EL RQ + + + + L+ +K LR+ E+ H
Sbjct: 1687 QIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIH 1746
Query: 180 TLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQ--LNDAG-------RNVFKEND 230
L+ L+ + ++ L ++ + ++L++R ++Q L +A +++ + D
Sbjct: 1747 ELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLD 1806
Query: 231 YLQKALAYHLKETDALQKNSQKLQ-------ESHTLLLHQKEINDLLVKEKIMQLVQQRS 283
Q+ALA +E +ALQ+ Q+ Q E L E + +KE+ +L +
Sbjct: 1807 EAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKE 1866
Query: 284 QIQTLQ-------KKVVNLETALSYM---TKEFESEVLKLQQHAMIENQAGQVEIDKLQH 333
Q + L+ ++V LE L + ++E E +L LQQ + Q +VE LQ
Sbjct: 1867 QARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQD 1926
Query: 334 -------LLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQV--KQQILISRKHYKQI 384
+L+ +D+E+ ++ +++ + E R +AL + K + K +
Sbjct: 1927 SWLQAQAVLKERDQELEALRAESQSSRHQE-EAARARAEALQEALGKAHAALQGKEQHLL 1985
Query: 385 AQAAFNLKMRAA 396
QA + + A+
Sbjct: 1986 EQAELSRSLEAS 1997
Score = 53.1 bits (126), Expect = 6e-07
Identities = 65/289 (22%), Positives = 132/289 (45%), Gaps = 25/289 (8%)
Query: 60 LAKSNE--DLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKL 117
L K N+ DL+++Q + + SVL +L QE++ + ++Q+ E EKD+
Sbjct: 1465 LKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIREL------EKDRE 1518
Query: 118 EQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIH 177
Q+ N LE Q + K+ MI ++ V+ +K+ + +E +L+EN E
Sbjct: 1519 TQR-----NVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKME-CQ 1572
Query: 178 QETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALA 237
Q+ ++ LE + ++ A + + E E Q + ++ + L + L
Sbjct: 1573 QKLIKELEG-----QRETQRVALTHLTLDLEERSQELQAQSSQI-HDLESHSTVLARELQ 1626
Query: 238 YHLKETDALQKNSQKLQESHTLLLHQKEIND---LLVKEKIMQLVQQRS-QIQTLQKKVV 293
+E + ++ ++LQ L E D +L KE+I L QR+ Q + L++ +
Sbjct: 1627 ERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLE 1686
Query: 294 NLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHL-LQMKDRE 341
++ +L +E ++ +Q+ A + + L+H+ L ++D+E
Sbjct: 1687 QIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKE 1735
Score = 49.7 bits (117), Expect = 7e-06
Identities = 87/375 (23%), Positives = 150/375 (40%), Gaps = 69/375 (18%)
Query: 48 LSRIKYRDTSRILAKSNEDLKKKQCK---MEKDIMSVLSYLKKQDQEKDNMIEKLKQQLN 104
L+ + + L K ++DL K Q + + + L + EK + +L Q L
Sbjct: 1233 LTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTEL-QDLQ 1291
Query: 105 ETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVEREL- 163
+ QEEK K E K N LE + + + + + + L+ + Q+ + Q EREL
Sbjct: 1292 RQLSQNQEEKSKWEGKQ----NSLESELMELHETMASLQSRLRRA-ELQRMEAQGERELL 1346
Query: 164 DDLKENLR-----------------NTERIHQETLRRLESRFFEEKHRLEQEAEKKIIML 206
KENL + I +E LR S + +E E E+
Sbjct: 1347 QAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERER----- 1401
Query: 207 AERAHHEAIVQLNDAGRNVFKEN-DYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKE 265
A+ + +L A +EN L + LA +E + L+ Q+L++ + E
Sbjct: 1402 AQALQEQG--ELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALE 1459
Query: 266 INDLLVKEKIMQLVQQRSQIQTLQK------------------------KVVNLETALSY 301
+ L +K++ ++ Q+ QIQ L+K ++ LE
Sbjct: 1460 LLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRET 1519
Query: 302 MTKEFESEVLKLQ-QHAMIENQAGQVEIDKLQHL--------LQMKDREMNRVKKLAKNI 352
E ++L+L+ + MIE+Q GQV+ K Q + L+ +M +KL K +
Sbjct: 1520 QRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKEL 1579
Query: 353 LDERTEVERFFLDAL 367
+R E +R L L
Sbjct: 1580 EGQR-ETQRVALTHL 1593
Score = 48.5 bits (114), Expect = 1e-05
Identities = 46/198 (23%), Positives = 92/198 (46%), Gaps = 18/198 (9%)
Query: 6 KDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNE 65
+D K K K ++T +++T L EA+ E+ E +R ++RD L + +
Sbjct: 953 QDMKVQKLKEQETTGILQTQ------------LQEAQRELKEAAR-QHRDDLAALQEESS 999
Query: 66 DLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKE--KAQEEKDKLEQKYTR 123
L + + ++K + + S L QD + + ++++++L ET+E + Q+E ++ + T
Sbjct: 1000 SLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTL 1059
Query: 124 QINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRR 183
+ E E + + + EL A+RQ + ++EL E LR + +
Sbjct: 1060 SLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLA 1119
Query: 184 LESRFFEE---KHRLEQE 198
E++ EE H EQ+
Sbjct: 1120 QEAQLLEELEASHITEQQ 1137
Score = 44.7 bits (104), Expect = 2e-04
Identities = 82/372 (22%), Positives = 159/372 (42%), Gaps = 47/372 (12%)
Query: 20 KLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDIM 79
+L + ++SV R +A A L+V K R+ L + N L+ + K E+
Sbjct: 621 QLEEENQSVCSRMEAAEQARNA-LQVDLAEAEKRREA---LWEKNTHLEAQLQKAEEAGA 676
Query: 80 SVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQK---A 136
+ + L+ +EK+ + +KL + ++ +E A + ++L Q+ RQ L +K
Sbjct: 677 ELQADLRDIQEEKEEIQKKLSESRHQ-QEAATTQLEQLHQEAKRQEEVLARAVQEKEALV 735
Query: 137 KEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLE 196
+E + L+A VER+ DL E L+ + LES F E
Sbjct: 736 REKAALEVRLQA----------VERDRQDLAEQLQGLSSAKE----LLESSLF------E 775
Query: 197 QEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETD-----ALQKNSQ 251
+ + +I + + I + A + E L+ L + + A ++ +Q
Sbjct: 776 AQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQ 835
Query: 252 KLQESHTLL-----LHQKEINDLLVK-EKIMQLVQQR--SQIQTLQKKVVNLETALSYMT 303
QE T L H+KE+N L K EK QQ +++L+++ + LE L
Sbjct: 836 AEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQ 895
Query: 304 KEFES-EVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVERF 362
E E+ + + ++ E+ Q++++ + + + + + K+LA D ++ER
Sbjct: 896 TEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELA----DASQQLERL 951
Query: 363 FLD-ALHQVKQQ 373
D + ++K+Q
Sbjct: 952 RQDMKVQKLKEQ 963
Score = 37.4 bits (85), Expect = 0.034
Identities = 53/258 (20%), Positives = 110/258 (42%), Gaps = 36/258 (13%)
Query: 88 QDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELK 147
+ E +E L + + Q +LE+ Q E++ Q + ++
Sbjct: 1986 EQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQED--------- 2036
Query: 148 AVRQFQKRKIQVERELDDLKENLRNTERIHQETL-RRLESRFFEEKHRLEQEAEKKIIML 206
V+Q Q+ Q + EL +E E++ +++L +R++ +EK L QE E++ I
Sbjct: 2037 -VQQLQQALAQRDEELRHQQER----EQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRG 2091
Query: 207 AERAHHEAIVQLNDAGRNVFKENDYLQK----ALAYHLKET---------DALQKNSQKL 253
++ E + L + + + + Q+ AL + K + D+L+ Q+
Sbjct: 2092 LHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRE 2151
Query: 254 QESHTLLLHQKEINDLLVKEKI----MQLVQQRSQIQTLQKKVVNLETALSYMTKEFESE 309
E L Q E ++ +EK + L Q ++ + +LQ+ + L+ ++ E +SE
Sbjct: 2152 LERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVL----ERDSE 2207
Query: 310 VLKLQQHAMIENQAGQVE 327
+LQ + +A + E
Sbjct: 2208 QQRLQDELELTRRALEKE 2225
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 65.9 bits (159), Expect = 9e-11
Identities = 63/317 (19%), Positives = 155/317 (48%), Gaps = 35/317 (11%)
Query: 33 KANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDI-----------MSV 81
KA+ + E E LS YR+T +NE+LKKK ++++ + ++V
Sbjct: 156 KADRYIEELTKERDALSLELYRNTI-----TNEELKKKNAELQEKLRLAESEKSEIQLNV 210
Query: 82 LSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGM 141
+K ++ K + + L E + +EE + E+K +Q ++ Q + ++ G
Sbjct: 211 KELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGK 270
Query: 142 IHTELKAVRQFQKRKIQVERELDDLKENLRNTERI--HQETLRRLESRFFEEKHRLEQEA 199
+ + + +R+ +KR + E+EL + ++ LR +++ +E ++ E + +E++ ++ ++
Sbjct: 271 MREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE 330
Query: 200 EK-----KIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQ 254
EK + + E+ E ++ D ++++++ L++ ++E + + + +K+Q
Sbjct: 331 EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK-EERMREQEKMWEQEEKMQ 389
Query: 255 ESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQ 314
E + +K++ + +E+ M R Q + +QK+ N+ KE++ + L Q
Sbjct: 390 EEERIREREKKMRE---EEETM-----REQEEKMQKQEENM---WEQEEKEWQQQRLPEQ 438
Query: 315 QHAMIENQAGQVEIDKL 331
+ + E + Q + +K+
Sbjct: 439 KEKLWEQEKMQEQEEKI 455
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/247 (15%), Positives = 114/247 (46%), Gaps = 19/247 (7%)
Query: 38 LWEARLEVTELSRI-----KYRDTSRILAKSNEDLKKKQCKMEKDIM-SVLSYLKKQDQ- 90
LWE + +I K RD + + + ++++ + ++D M ++ Q+Q
Sbjct: 442 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 501
Query: 91 ---------EKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGM 141
E+D + + ++++ E K+ Q+E+ E+K T++ + +K +E
Sbjct: 502 MWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEER 561
Query: 142 IHTELKAVRQFQKRKIQVERELDDLKENLRNTER---IHQETLRRLESRFFEEKHRLEQE 198
+ K +R+ ++ + E ++ + +E +R E +E ++ E + +E++ ++ ++
Sbjct: 562 MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 621
Query: 199 AEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHT 258
E+ + E E ++ + ++++ + +++ ++ + +Q +K++E
Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
Query: 259 LLLHQKE 265
+ Q+E
Sbjct: 682 KMQGQEE 688
Score = 43.5 bits (101), Expect = 5e-04
Identities = 51/319 (15%), Positives = 148/319 (46%), Gaps = 23/319 (7%)
Query: 6 KDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNE 65
K+ ++ + + ++ KKL + +E + ++ + +WE ++ E +R R L + +
Sbjct: 290 KELREQEKELREQKKLREQEEQMQEQEE---KMWEQEEKMREQEEKMWRQEER-LWEQEK 345
Query: 66 DLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQI 125
+++++ KM +++ E+D + + ++++ E +EK E+++K++++ +I
Sbjct: 346 QMREQEQKMRDQ--------EERMWEQDERLREKEERMRE-QEKMWEQEEKMQEE--ERI 394
Query: 126 NELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLE 185
E E + ++ E M E K +Q + Q E+E + + + QE ++ E
Sbjct: 395 REREKKMREE--EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQE 452
Query: 186 SRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDA 245
+ +E++ ++ + E M + ++ + ++++ + ++ + +
Sbjct: 453 EKIWEQEEKIRDQEE----MWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 508
Query: 246 LQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKE 305
+ + ++L+E + QK++ K + + Q++ + Q++ + E + K+
Sbjct: 509 MWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKK 568
Query: 306 F--ESEVLKLQQHAMIENQ 322
E E+++ Q+ M E +
Sbjct: 569 MREEEEMMREQEEKMQEQE 587
Score = 39.3 bits (90), Expect = 0.009
Identities = 32/187 (17%), Positives = 82/187 (43%), Gaps = 2/187 (1%)
Query: 6 KDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNE 65
++KK + + ++ K E + +WE ++ E + ++ + E
Sbjct: 565 REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE 624
Query: 66 DLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQI 125
D ++Q +M + + +++ E++ + + ++++ E +EK Q +++K+ ++ +
Sbjct: 625 DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684
Query: 126 NELEGQFHQKAKEIGMIHTELKAVRQF--QKRKIQVERELDDLKENLRNTERIHQETLRR 183
+ E Q+ K G + Q+ K+ + E+ + +E +R+ + QE L
Sbjct: 685 GQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPE 744
Query: 184 LESRFFE 190
E R E
Sbjct: 745 HEERCSE 751
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 65.1 bits (157), Expect = 2e-10
Identities = 88/369 (23%), Positives = 164/369 (44%), Gaps = 70/369 (18%)
Query: 65 EDLKKKQCKMEKDIMSVLSYLKKQDQE-----------------KDNMIEKLKQQLNETK 107
E+LKKK ++ +I V L ++D E IE LK+ L +
Sbjct: 455 EELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKE 514
Query: 108 EKAQ-------------EEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQK 154
++A EEK+ + K T+QI ++ +K + G IH +LK + ++
Sbjct: 515 QRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMA---EEKGTQAGEIH-DLKDMLDVKE 570
Query: 155 RKIQV-ERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHE 213
RK+ V ++++++L+E LR+ E+ R++S +A+ A E
Sbjct: 571 RKVNVLQKKIENLQEQLRDKEKQMSSLKERVKS----------LQADTTNTDTALTTLEE 620
Query: 214 AIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLL---LHQKEINDLL 270
A+ + + ++ D ++ +E D +K+ + L+E +LL L +KE + L
Sbjct: 621 ALAEKERTIERLKEQRDRDERE---KQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLD 677
Query: 271 VKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKE---FESEVLKLQQHAMIENQAGQVE 327
+KE L S ++ LE AL +E ES+ LK A +E +A
Sbjct: 678 LKEHASSLA---SSGLKKDSRLKTLEIALEQKKEECLKMESQ-LKKAHEAALEARASPEM 733
Query: 328 IDKLQHL----LQMKDR------EMNRVKKLAKNILDERTEVERFFLDALHQVKQQ--IL 375
D++QHL + KD E++R+ ++ K + +E+ + ++ + QVK Q +
Sbjct: 734 SDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKV 793
Query: 376 ISRKHYKQI 384
+ KH +Q+
Sbjct: 794 ANLKHKEQV 802
Score = 61.2 bits (147), Expect = 2e-09
Identities = 80/350 (22%), Positives = 158/350 (45%), Gaps = 53/350 (15%)
Query: 13 SKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQC 72
S G +KT E +++ K E S++K + + A+++ ++ +
Sbjct: 687 SSGLKKDSRLKTLEIALEQKKEECLKME--------SQLKKAHEAALEARASPEMSDRIQ 738
Query: 73 KMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQF 132
+E++I K E D ++E LK+ NE + +KDK +I ELE Q
Sbjct: 739 HLEREITRYKDESSKAQAEVDRLLEILKEVENE-----KNDKDK-------KIAELERQV 786
Query: 133 HQKAKEIGMIHTELKAVRQFQKRK-IQVERELDDLKENLRNTERIHQETLRRLESRFFEE 191
+ K++ LK Q +K+K Q+ E ++NL ++ + Q++LR+ + R E
Sbjct: 787 KDQNKKVA----NLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEE- 841
Query: 192 KHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQ 251
LE+ + + + AER + Q A N K+ + L A+ +E ++++
Sbjct: 842 ---LEEALRESVQITAER--EMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS 896
Query: 252 KLQESHTLLLHQKEINDLLVK-----EKIMQLVQQRSQIQTLQKKVVNLETA-LSYMTKE 305
Q+S L + + +L + E+++++ +Q + + + +K N+ LS K+
Sbjct: 897 STQQS--LAEKETHLTNLRAERRKHLEEVLEM-KQEALLAAISEKDANIALLELSSSKKK 953
Query: 306 FESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDE 355
+ EV L++ E D+L + Q+K + NR+K +A N D+
Sbjct: 954 TQEEVAALKR-----------EKDRL--VQQLKQQTQNRMKLMADNYEDD 990
Score = 48.9 bits (115), Expect = 1e-05
Identities = 74/364 (20%), Positives = 151/364 (41%), Gaps = 63/364 (17%)
Query: 40 EARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDIMSV---LSYLKKQDQEKDNMI 96
E ++ V + ++ R K LK++ ++ D + L+ L++ EK+ I
Sbjct: 570 ERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTI 629
Query: 97 EKLKQQLNETKEKAQEEKDKLE---QKYTRQINELEGQFHQKAKEI--------GMIHTE 145
E+LK+Q + + + QEE D + + +++ L+G +K + + +
Sbjct: 630 ERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSG 689
Query: 146 LKAVRQFQKRKIQVERELDDLKENLRNTERIHQ---------------ETLRRLESRFFE 190
LK + + +I +E++ ++ + ++ H+ + L R +R+ +
Sbjct: 690 LKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKD 749
Query: 191 EKHRLEQEAEKKIIMLAERAHH---------EAIVQLNDAGRNV--FKENDYLQKALAYH 239
E + + E ++ + +L E + E Q+ D + V K + ++K +
Sbjct: 750 ESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQ 809
Query: 240 LKE-----TDALQKNSQKLQESHTLLLHQKEINDL---------LVKEKIMQLVQQRSQI 285
+ E D L +SQ+LQ+S L I +L + E+ M L Q+ S
Sbjct: 810 MLEEARRREDNLNDSSQQLQDS--LRKKDDRIEELEEALRESVQITAEREMVLAQEESAR 867
Query: 286 QTLQKKVVNLETALSYMTKEFESEVLKL----QQHAMIENQAGQVEIDKLQHL---LQMK 338
+K+V L A+ + +E ES KL Q A E + ++ +HL L+MK
Sbjct: 868 TNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMK 927
Query: 339 DREM 342
+
Sbjct: 928 QEAL 931
Score = 39.3 bits (90), Expect = 0.009
Identities = 57/275 (20%), Positives = 122/275 (44%), Gaps = 24/275 (8%)
Query: 90 QEKDNMIEKLKQQLNET---KEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTEL 146
Q +DN I L+ QL E + +++ + E K + +N ++ + + K+
Sbjct: 145 QARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKE------- 197
Query: 147 KAVRQFQKRKIQVERE----LDDLKENLRNTERIHQETLR--RLESRFFEEKHRLEQEAE 200
+A+R+ + KI + +E + + ++++ T + Q+ LR R ++ F++ + E
Sbjct: 198 RALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSS-SRTGE 256
Query: 201 KKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLL 260
+ L E E +L+ KE L+K L + ++ ES L
Sbjct: 257 PCVAELTE----ENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKL 312
Query: 261 LHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIE 320
L + L K + R ++ + V +LE+ L KE E+ +L+ + H E
Sbjct: 313 LEMLQSKGLSAKATEEDHERTR-RLAEAEMHVHHLESLLEQ--KEKENSMLREEMHRRFE 369
Query: 321 NQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDE 355
N + LQ +++MKD +++ +++ +++ +E
Sbjct: 370 NAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEE 404
>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
Length = 898
Score = 65.1 bits (157), Expect = 2e-10
Identities = 103/446 (23%), Positives = 186/446 (41%), Gaps = 68/446 (15%)
Query: 33 KANASLWEARLEVTELSRIKY---RDTSRILAKSNEDLKKKQCKMEKDIMSVLSYLKKQD 89
+AN EAR E E +KY S L K E L+KK K++ + +K+
Sbjct: 296 QANKKCEEARQE-KEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLS 354
Query: 90 QEKDNMIEKLKQQLNETKE----KAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTE 145
QEK + QL ETKE + E DKL++ + +++ ++ E+ H E
Sbjct: 355 QEKGRL-----HQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDS-HKE 408
Query: 146 LK-AVRQFQKRKIQVERELDDLKENLRNTERIHQET----LRRLESRFFEEKHRLEQEAE 200
K +++ + Q + E D +++N ++ + +QE+ L+++ K LE++ +
Sbjct: 409 TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQ 468
Query: 201 KKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLK--ETDALQKNSQKLQESHT 258
+K L HH I +L D R FKE + L +K E + L+ + +
Sbjct: 469 EKSDQL--EMHHAKIKELEDLKRT-FKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEI 525
Query: 259 LLLHQKEINDLLVKEKIMQLVQQRSQ-----IQTLQKKVVNLETALSYMTKEFE------ 307
+ + EI +LL K K +Q++ Q I+ L+++V +L + ++ + K+ E
Sbjct: 526 INRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRE 585
Query: 308 SEVLKLQQHAMIENQAGQVEIDKLQHLL---------------QMKDREMNRVKKLAKNI 352
SE+L + +N Q E + LQ QMK +N +L K
Sbjct: 586 SELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKEE 645
Query: 353 LDERTEVERFFLDA-------------LHQVKQQILISR-KHYKQIAQAAFNLKMRAACT 398
+ EV+ + + ++K +++ R KH I L+
Sbjct: 646 ELRKEEVQTLQAELACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKL 705
Query: 399 GRTE---YPK-IRTFDGREHSTNSVN 420
+ E Y K + + R S+ S+N
Sbjct: 706 DQVESGSYDKEVSSMGSRSSSSGSLN 731
Score = 62.4 bits (150), Expect = 1e-09
Identities = 73/356 (20%), Positives = 171/356 (48%), Gaps = 34/356 (9%)
Query: 16 KDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKME 75
++ KL + S V + K + +A ++ + ++ K ++T+ L ++ E+ + +
Sbjct: 376 REIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQ----IR 431
Query: 76 KDIMSVLSYLKKQDQEKDNMIE-KLKQQLNETKEKAQEEKDKLEQKYTR--QINELEGQF 132
K+ ++ ++ ++ K N ++ KL+ E +++ QE+ D+LE + + ++ +L+ F
Sbjct: 432 KNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTF 491
Query: 133 HQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLES--RFFE 190
+ E+ + T++K + + +++ E EL KE + + Q L ++++ + E
Sbjct: 492 KEGMDELRTLRTKVKCL---EDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQE 548
Query: 191 EKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDAL-QKN 249
+ R +QE E E + LN ++ K+ + +K + L T+ L KN
Sbjct: 549 QLQRGKQEIENL---------KEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKN 599
Query: 250 SQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESE 309
+Q ES++L Q + + + E Q +SQ + +++ +NLE+ L + + E
Sbjct: 600 AQLQSESNSL---QSQFDKVSCSES-----QLQSQCEQMKQTNINLESRLLKEEELRKEE 651
Query: 310 VLKLQQH---AMIENQAGQVEIDKLQ-HLLQMKDREMNRVKKLAKNILDERTEVER 361
V LQ E +A ++++L+ L+ + + + +K L K + R ++++
Sbjct: 652 VQTLQAELACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKLDQ 707
Score = 55.1 bits (131), Expect = 2e-07
Identities = 86/368 (23%), Positives = 169/368 (45%), Gaps = 32/368 (8%)
Query: 19 KKLIKTD----ESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKM 74
KKLIK + E VD +L E + TE + ++ +T + L E+L K+
Sbjct: 210 KKLIKENKKHQELFVDICSEKDNLREELKKRTETEK-QHMNTIKQLESRIEELNKEVKAS 268
Query: 75 EKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQ 134
+++ K Q+ + + +Q N+ E+A++EK+ + KY R E E +
Sbjct: 269 RDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVR--GEKESLDLR 326
Query: 135 KAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQ--ETLRRLESRFFEEK 192
K KE T K +R K ++E+ + +K+ + R+HQ ET +R E
Sbjct: 327 KEKE-----TLEKKLRDANK---ELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREI 378
Query: 193 HRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQK 252
+L+++ +I + + A ++ +++ K + K L +E D ++KN Q
Sbjct: 379 DKLKEDINSHVIKV-KWAQNKLKAEMDSHKETKDKLKETTTK-LTQAKEEADQIRKNCQD 436
Query: 253 L----QESHTLLLHQKEINDLLVKEKIMQLVQQRS-QIQTLQKKVVNLETALSYMTKEFE 307
+ QES + ++ + + K ++ + +Q++S Q++ K+ LE L KE
Sbjct: 437 MIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELED-LKRTFKEGM 495
Query: 308 SEVLKLQQHA-MIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDA 366
E+ L+ +E++ + E D+L ++ +NR K +N+LD+ ++ +
Sbjct: 496 DELRTLRTKVKCLEDERLRTE-DELSKYKEI----INRQKAEIQNLLDKVKTADQ-LQEQ 549
Query: 367 LHQVKQQI 374
L + KQ+I
Sbjct: 550 LQRGKQEI 557
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 65.1 bits (157), Expect = 2e-10
Identities = 83/394 (21%), Positives = 188/394 (47%), Gaps = 60/394 (15%)
Query: 40 EARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKME---KDIMSVLSYLKKQDQEKDNMI 96
EA+LE + ++++ + ++ +D+ KQ +E + + +KK++ +KD +
Sbjct: 774 EAQLEKKDQ---QFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEAL 830
Query: 97 EKLKQQLNETKEKAQEEKDKLE---QKYTRQINELEG-------QFHQKAKEIGMIHTEL 146
+ L+ Q++E K ++ LE ++ +N+LEG Q +K++E+ + EL
Sbjct: 831 KALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKEL 890
Query: 147 K----AVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEK- 201
K ++++ ++ + ++ L ++ L+ E I L +++ ++ +LEQE +K
Sbjct: 891 KIKNHSLQETSEQNVILQHTLQQQQQMLQQ-ETIRNGELEDTQTKLEKQVSKLEQELQKQ 949
Query: 202 ---------KIIMLAERAHHEA------IVQLNDAGRNVFKENDYLQKALAYHLKETDAL 246
K+ E A HEA +++L R V E D ++ L+ KE L
Sbjct: 950 RESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHL 1009
Query: 247 QKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEF 306
+++ + +H ++ D+++ + +L ++ + ++ L+K + ET L+ +
Sbjct: 1010 KRDGE------NKAMHLSQL-DMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQ-- 1060
Query: 307 ESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDA 366
+ EVL+ + ++N G+++ L+ L +++D V + A+ L+E+ +
Sbjct: 1061 KREVLETE----LQNAHGELK-STLRQLQELRD-----VLQKAQLSLEEKYTTIKDLTAE 1110
Query: 367 LHQVKQQILISRKHYKQIAQAA----FNLKMRAA 396
L + K +I ++ ++ QA + LK RAA
Sbjct: 1111 LRECKMEIEDKKQELLEMDQALKERNWELKQRAA 1144
Score = 55.8 bits (133), Expect = 9e-08
Identities = 81/393 (20%), Positives = 174/393 (44%), Gaps = 54/393 (13%)
Query: 3 SKGKDKKKGKSKGKDT----KKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSR 58
+K K +K+ K K ++ K+L + S+ + ++ N L + + ++ ++T R
Sbjct: 868 NKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHT---LQQQQQMLQQETIR 924
Query: 59 ILAKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLE 118
N +L+ Q K+EK + + L+KQ +++ EKL+ ++ E E A E D
Sbjct: 925 -----NGELEDTQTKLEKQVSKLEQELQKQ---RESSAEKLR-KMEEKCESAAHEADLKR 975
Query: 119 QKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQ 178
QK + EL G Q E+ EL + +K + ++R+ ++ +L + I
Sbjct: 976 QK----VIELTGTARQVKIEMDQYKEELS---KMEKEIMHLKRDGENKAMHLSQLDMILD 1028
Query: 179 ETLRRLESR--FFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKAL 236
+T LE + +E +L+ E ++ EA+ + + + L+ L
Sbjct: 1029 QTKTELEKKTNAVKELEKLQHSTETELT--------EALQKREVLETELQNAHGELKSTL 1080
Query: 237 AYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLE 296
+ D LQK L+E +T +K+ +L + + +I+ +++++ ++
Sbjct: 1081 RQLQELRDVLQKAQLSLEEKYT-----------TIKDLTAELRECKMEIEDKKQELLEMD 1129
Query: 297 TALSYMTKEFESEVLKLQQHAM-IENQAGQVE--IDKLQHLLQMKDREMNRVKKLAKNIL 353
AL E + ++ M I G++E I KL+ L+ + E+ K +++
Sbjct: 1130 QALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLN 1189
Query: 354 DERTEVERFFLDALHQVKQQILISRKHYKQIAQ 386
D+ +A Q++++ I ++ ++I+Q
Sbjct: 1190 DK-------LQNAKEQLREKEFIMLQNEQEISQ 1215
Score = 52.0 bits (123), Expect = 1e-06
Identities = 90/380 (23%), Positives = 174/380 (45%), Gaps = 63/380 (16%)
Query: 26 ESVVDRAKANASLWEARL--EVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDIMSVLS 83
E ++++A +N+S E+ + + ++L ++ + +I+A S+ + K ++E+++M
Sbjct: 676 EELLEKA-SNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSS--IAAKNAELEQELM---- 728
Query: 84 YLKKQDQEKDNMIEKLKQQLNETKEK-----AQEEKDKLEQ--KYTRQINELEGQFHQKA 136
EK+ I L+ +N EK + +K LEQ + +QI LE Q +K
Sbjct: 729 -------EKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKD 781
Query: 137 KEIGMIHTELKAVRQ----FQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEK 192
++ + ++Q Q ++R L + K ++ E L+ L+++ EE
Sbjct: 782 QQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEET 841
Query: 193 HRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQK------ALAYHLK-ETDA 245
++ Q + E E ++ LN N K L+K L LK + +
Sbjct: 842 IKVRQ-----LDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHS 896
Query: 246 LQKNS-QKLQESHTL-----LLHQKEINDLLVKEKIMQLVQQRSQI-QTLQKKVVNLETA 298
LQ+ S Q + HTL +L Q+ I + +++ +L +Q S++ Q LQK+ +
Sbjct: 897 LQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEK 956
Query: 299 LSYMTKEFESEV----LKLQQHAMIENQAGQV--EIDKLQHLLQMKDREMNRVKKLAKN- 351
L M ++ ES LK Q+ + A QV E+D+ + L ++E+ +K+ +N
Sbjct: 957 LRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENK 1016
Query: 352 ---------ILDE-RTEVER 361
ILD+ +TE+E+
Sbjct: 1017 AMHLSQLDMILDQTKTELEK 1036
Score = 45.8 bits (107), Expect = 1e-04
Identities = 61/288 (21%), Positives = 130/288 (45%), Gaps = 27/288 (9%)
Query: 67 LKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQIN 126
L++ + K+E+ V+ + + K+ I+ L +TK+ + E+ + E Y +
Sbjct: 307 LREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAE-- 364
Query: 127 ELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDL-KENLRNTER--IHQETLRR 183
EL F Q K++ + + + Q + +ER L + KEN R ER +++ L
Sbjct: 365 ELSKAFQQYKKKVA------EKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEI 418
Query: 184 LESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKET 243
L+ + + K EK IM + + E + QL ++ +++ K L+ L++
Sbjct: 419 LKEKLRQLKEENNNGKEKLRIMAVKNS--EVMAQLTESRQSILKLESELENKDEI-LRDK 475
Query: 244 DALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETA----- 298
+L +++L+ + Q E DL +E + R ++++L+K + L
Sbjct: 476 FSLMNENRELK---VRVAAQNERLDLCQQE----IESSRVELRSLEKIISQLPLKRELFG 528
Query: 299 -LSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRV 345
SY++K S + + +A ++ I +L+ L +K+ E+ ++
Sbjct: 529 FKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKL 576
Score = 41.2 bits (95), Expect = 0.002
Identities = 63/302 (20%), Positives = 131/302 (43%), Gaps = 56/302 (18%)
Query: 19 KKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAK--------SNEDLKKK 70
++L++ D+++ +R N L + +VT L + K +L+ K
Sbjct: 1123 QELLEMDQALKER---NWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELK 1179
Query: 71 QC-KMEKDIMSVLSYLKKQDQEKD--------------NMIEKLKQQLNETKEKAQEEKD 115
+C K + + L K+Q +EK+ IE+ +Q++ E + +E++
Sbjct: 1180 ECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQ 1239
Query: 116 KLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTER 175
+ +Y I +L + +++ HTEL R +++Q +RE++ L L + ++
Sbjct: 1240 YIATQYKEAI-DLGQELRLTREQVQNSHTELAEARH---QQVQAQREIERLSSELEDMKQ 1295
Query: 176 IHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKA 235
+ +E + H E+ K+ AH EA +Q + + E + L++
Sbjct: 1296 LSKE-------KDAHGNHLAEELGASKV----REAHLEARMQAEI--KKLSAEVESLKE- 1341
Query: 236 LAYHL-----KETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQK 290
AYH+ +E A K S Q+S +++N+ L K K ++L + + + L +
Sbjct: 1342 -AYHMEMISHQENHAKWKISADSQKSSV-----QQLNEQLEKAK-LELEEAQDTVSNLHQ 1394
Query: 291 KV 292
+V
Sbjct: 1395 QV 1396
Score = 39.3 bits (90), Expect = 0.009
Identities = 53/253 (20%), Positives = 112/253 (44%), Gaps = 35/253 (13%)
Query: 93 DNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQF 152
+ I L+ +++ + +E ++KLEQ QK M+ + +++++
Sbjct: 290 EEQIINLEAEVSAQDKVLREAENKLEQS-------------QK-----MVIEKEQSLQES 331
Query: 153 QKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAH- 211
++ I+++ +L + + + ER E L EE + Q+ +KK+ E+
Sbjct: 332 KEECIKLKVDLLEQTKQGKRAERQRNEALYNA-----EELSKAFQQYKKKVAEKLEKVQA 386
Query: 212 HEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLV 271
E I++ N N KEN LQ+ + E + L++ ++L+E + + I +
Sbjct: 387 EEEILERNLT--NCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKN 444
Query: 272 KEKIMQLVQQRSQIQTLQKKVVN----LETALSYMTKEFESEVLKLQQHAMI-----ENQ 322
E + QL + R I L+ ++ N L S M + E +V Q+ + E +
Sbjct: 445 SEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIE 504
Query: 323 AGQVEIDKLQHLL 335
+ +VE+ L+ ++
Sbjct: 505 SSRVELRSLEKII 517
Score = 38.9 bits (89), Expect = 0.012
Identities = 51/247 (20%), Positives = 104/247 (42%), Gaps = 42/247 (17%)
Query: 149 VRQFQKRKIQVERELDDLKENLRNT----ERIHQETLRRLESRFFEEKHRLEQEAEKK-- 202
+ + + + IQ+E E DLK N+ + + I +E L + + +LE E KK
Sbjct: 643 IEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASN-----SSKLESEMTKKCS 697
Query: 203 -IIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETD----------ALQKNSQ 251
++ L ++ + + + A +N E + ++K ET+ A +K +
Sbjct: 698 QLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKK 757
Query: 252 KLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVV-------NLETALSYMTK 304
E H + Q E + +++K Q +Q + LQ+ ++ +L+ L+
Sbjct: 758 IHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKG 817
Query: 305 EFESEVLKLQQH-AMIENQAGQ-----------VEIDKLQHLLQMKDREMNRVKKLAKNI 352
E + E +K + ++NQ + +EI K + +L + E N+ +K K +
Sbjct: 818 EMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNK-EKFEKQL 876
Query: 353 LDERTEV 359
+ EV
Sbjct: 877 KKKSEEV 883
Score = 33.5 bits (75), Expect = 0.49
Identities = 31/148 (20%), Positives = 74/148 (50%), Gaps = 19/148 (12%)
Query: 247 QKNSQKLQESHTLLLHQKEINDLLVKEK-----IMQLVQQRSQIQTLQKKVVNLETALSY 301
Q+N+ + ++H+L+ + I+ L + + + QQ + + L+++++NLE +S
Sbjct: 243 QQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAASVPILEEQIINLEAEVSA 302
Query: 302 MTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTE--- 358
K KL+ Q+ ++ I+K Q L + K+ + KL ++L++ +
Sbjct: 303 QDKVLREAENKLE-------QSQKMVIEKEQSLQESKEECI----KLKVDLLEQTKQGKR 351
Query: 359 VERFFLDALHQVKQQILISRKHYKQIAQ 386
ER +AL+ ++ +++ K++A+
Sbjct: 352 AERQRNEALYNAEELSKAFQQYKKKVAE 379
>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
Length = 1173
Score = 64.7 bits (156), Expect = 2e-10
Identities = 76/349 (21%), Positives = 169/349 (48%), Gaps = 36/349 (10%)
Query: 16 KDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKME 75
+++ K+ TD ++++R + E ++ + ++++ D R + + N++ ++KQ K++
Sbjct: 643 EESAKVCLTDVTIMERFQMELKDVERKI-AQQAAKLQGIDLDRTVQQVNQEKQEKQHKLD 701
Query: 76 KDIMSVLSYLKKQDQEKDNMIEKLKQQLNETK-EKAQ-----EEKDKLEQKYTRQINELE 129
+ S + +K Q++ I+ LK NE K EK Q + + +LE++ E++
Sbjct: 702 T-VSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELSTEVQ 760
Query: 130 GQFHQ--KAKE-IGMIHTELKAVRQFQKRKIQ--------VERELDDLKENLRNTERIHQ 178
+ + AKE + + T L+ +Q ++ I + +L+D+KE ++N +
Sbjct: 761 SLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIHGYMK 820
Query: 179 ETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAY 238
+ ++ + K + E E K I L+E H+ ++N+ R + ++ D QK
Sbjct: 821 DIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKE--KINEDMRLMRQDID-TQKIQER 877
Query: 239 HLKETDALQKNSQKLQE-SHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLE- 296
L++ L+K +++L+E H KE+ MQ++Q +S+ Q L++ + N++
Sbjct: 878 WLQDNLTLRKRNEELKEVEEERKQHLKEMGQ-------MQVLQMKSEHQKLEENIDNIKR 930
Query: 297 ---TALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREM 342
AL K +E E++ ++ + E Q E + ++ M+ E+
Sbjct: 931 NHNLALG-RQKGYEEEIIHFKKE-LREPQFRDAEEKYREMMIVMRTTEL 977
Score = 62.0 bits (149), Expect = 1e-09
Identities = 91/434 (20%), Positives = 190/434 (43%), Gaps = 75/434 (17%)
Query: 6 KDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNE 65
+DKK G + +I+ ++ + + + L+ E S + + + L K+
Sbjct: 294 RDKKTGLGR------IIELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAER 347
Query: 66 DLKK--KQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNE--------------TKEK 109
+L K K +E M V+S L+ + + D + KL Q++ + TK+K
Sbjct: 348 ELSKAEKNSNVETLKMEVIS-LQNEKADLDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDK 406
Query: 110 AQEEKD--KLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVEREL---D 164
A +++ K++ +++ ++ L G F K + +H++ K + Q + R ++ +EL +
Sbjct: 407 ADKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASSE 466
Query: 165 DLKENLRNTERIHQETLRRLESRFFE---------EKHRLEQEAEKK-----IIMLAERA 210
K ++ N + +E L E + F+ + RL++E EK ++ A
Sbjct: 467 QNKNHINNELKRKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEIEKSSKQRAMLAGATAV 526
Query: 211 HHEAIVQLNDAGRN-------VFKENDYLQKALA----------YHLKETDA-LQKNSQK 252
+ + I QL D ++ VF+ LQ+ ++ LK T++ L+K ++
Sbjct: 527 YSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQSKLRLAPDKLKSTESELKKKEKR 586
Query: 253 LQESHTLLLHQKEINDLLVKEKIMQLVQQRSQ-----IQTLQKKVVNLETALSYMTKEFE 307
E L+ ++ I DL KEK + ++ + Q IQ L+ + ET L + E E
Sbjct: 587 RDEMLGLVPMRQSIIDL--KEKEIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEE 644
Query: 308 SEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRV--KKLAKNILDERTEVERFFLD 365
S + L ++E Q+E+ ++ + + ++ + + + + E+ E +
Sbjct: 645 SAKVCLTDVTIMER--FQMELKDVERKIAQQAAKLQGIDLDRTVQQVNQEKQEKQH---- 698
Query: 366 ALHQVKQQILISRK 379
L V +I ++RK
Sbjct: 699 KLDTVSSKIELNRK 712
Score = 54.7 bits (130), Expect = 2e-07
Identities = 73/321 (22%), Positives = 135/321 (42%), Gaps = 58/321 (18%)
Query: 66 DLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIE--KLKQQLNETKEKAQEEKDKLEQKYTR 123
DL+ K + S S LKK+++ +D M+ ++Q + + KEK E Q R
Sbjct: 561 DLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLVPMRQSIIDLKEKEIPELRNKLQNVNR 620
Query: 124 QINELEGQFHQKAKEIGMIH----------TELKAVRQFQKRKIQVERELDDLKENLRNT 173
I L+ ++ +G I T++ + +FQ VER++ L+
Sbjct: 621 DIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGI 680
Query: 174 ERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQ 233
+ T++++ E++H+L+ + K ++LN R + ++ Q
Sbjct: 681 DL--DRTVQQVNQEKQEKQHKLDTVSSK--------------IELN---RKLIQD----Q 717
Query: 234 KALAYHLKETDALQKNSQKLQESHTLLLHQK-EINDLLVKEKIMQLVQQRSQIQTLQKKV 292
+ HLK T K S+KLQ S L Q+ E + + ++ L ++ I+ +++V
Sbjct: 718 QEQIQHLKSTTNELK-SEKLQISTNLQRRQQLEEQTVELSTEVQSLYRE---IKDAKEQV 773
Query: 293 VNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNI 352
LET L +E E + K +N + ++ DKL N +K+ KNI
Sbjct: 774 SPLETTLEKFQQEKEELINK-------KNTSNKIAQDKL-----------NDIKEKVKNI 815
Query: 353 LDERTEVERFFLDALHQVKQQ 373
++E + D K+Q
Sbjct: 816 HGYMKDIENYIQDGKDDYKKQ 836
Score = 54.3 bits (129), Expect = 3e-07
Identities = 75/347 (21%), Positives = 157/347 (45%), Gaps = 37/347 (10%)
Query: 56 TSRILAKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKD 115
+S+ + KS E+ K+I LS + K D E ++ K+Q+ + + +E+ +
Sbjct: 97 SSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEI-KALDSRKKQMEKDNSELEEKME 155
Query: 116 KLEQKYTRQINEL----EGQFHQKAKEIGMIHTELKAVRQ------FQKRKIQVER---- 161
K+ Q Q+N+L + +K +++ H EL+ + + +K ++ VE+
Sbjct: 156 KVFQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQ 215
Query: 162 -ELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLND 220
+ D +E++R + + Q +LE FE E++ + ++ ER EA + +
Sbjct: 216 LQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEGEA--KTAN 273
Query: 221 AGRNVFKENDYLQKALAYHLKETDALQKNSQ---KLQESHTLLLHQKEINDLLVKEKIMQ 277
N F E + L++ K+ D ++ ++ E + +L +K+ VK ++ Q
Sbjct: 274 QLMNDFAEKETLKQ------KQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQQ 327
Query: 278 LVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQM 337
L +I L ++++ E LS K E LK++ +I Q + ++D+ L+
Sbjct: 328 LEGSSDRILELDQELIKAERELSKAEKNSNVETLKME---VISLQNEKADLDR---TLRK 381
Query: 338 KDREMNRVKKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQI 384
D+EM ++ + RT++E D + +Q I +H ++
Sbjct: 382 LDQEMEQL----NHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDEL 424
>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
Length = 1312
Score = 64.7 bits (156), Expect = 2e-10
Identities = 76/349 (21%), Positives = 169/349 (48%), Gaps = 36/349 (10%)
Query: 16 KDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKME 75
+++ K+ TD ++++R + E ++ + ++++ D R + + N++ ++KQ K++
Sbjct: 782 EESAKVCLTDVTIMERFQMELKDVERKI-AQQAAKLQGIDLDRTVQQVNQEKQEKQHKLD 840
Query: 76 KDIMSVLSYLKKQDQEKDNMIEKLKQQLNETK-EKAQ-----EEKDKLEQKYTRQINELE 129
+ S + +K Q++ I+ LK NE K EK Q + + +LE++ E++
Sbjct: 841 T-VSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELSTEVQ 899
Query: 130 GQFHQ--KAKE-IGMIHTELKAVRQFQKRKIQ--------VERELDDLKENLRNTERIHQ 178
+ + AKE + + T L+ +Q ++ I + +L+D+KE ++N +
Sbjct: 900 SLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIHGYMK 959
Query: 179 ETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAY 238
+ ++ + K + E E K I L+E H+ ++N+ R + ++ D QK
Sbjct: 960 DIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKE--KINEDMRLMRQDID-TQKIQER 1016
Query: 239 HLKETDALQKNSQKLQE-SHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLE- 296
L++ L+K +++L+E H KE+ MQ++Q +S+ Q L++ + N++
Sbjct: 1017 WLQDNLTLRKRNEELKEVEEERKQHLKEMGQ-------MQVLQMKSEHQKLEENIDNIKR 1069
Query: 297 ---TALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREM 342
AL K +E E++ ++ + E Q E + ++ M+ E+
Sbjct: 1070 NHNLALG-RQKGYEEEIIHFKKE-LREPQFRDAEEKYREMMIVMRTTEL 1116
Score = 62.0 bits (149), Expect = 1e-09
Identities = 91/434 (20%), Positives = 190/434 (43%), Gaps = 75/434 (17%)
Query: 6 KDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNE 65
+DKK G + +I+ ++ + + + L+ E S + + + L K+
Sbjct: 433 RDKKTGLGR------IIELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAER 486
Query: 66 DLKK--KQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNE--------------TKEK 109
+L K K +E M V+S L+ + + D + KL Q++ + TK+K
Sbjct: 487 ELSKAEKNSNVETLKMEVIS-LQNEKADLDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDK 545
Query: 110 AQEEKD--KLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVEREL---D 164
A +++ K++ +++ ++ L G F K + +H++ K + Q + R ++ +EL +
Sbjct: 546 ADKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASSE 605
Query: 165 DLKENLRNTERIHQETLRRLESRFFE---------EKHRLEQEAEKK-----IIMLAERA 210
K ++ N + +E L E + F+ + RL++E EK ++ A
Sbjct: 606 QNKNHINNELKRKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEIEKSSKQRAMLAGATAV 665
Query: 211 HHEAIVQLNDAGRN-------VFKENDYLQKALA----------YHLKETDA-LQKNSQK 252
+ + I QL D ++ VF+ LQ+ ++ LK T++ L+K ++
Sbjct: 666 YSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQSKLRLAPDKLKSTESELKKKEKR 725
Query: 253 LQESHTLLLHQKEINDLLVKEKIMQLVQQRSQ-----IQTLQKKVVNLETALSYMTKEFE 307
E L+ ++ I DL KEK + ++ + Q IQ L+ + ET L + E E
Sbjct: 726 RDEMLGLVPMRQSIIDL--KEKEIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEE 783
Query: 308 SEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRV--KKLAKNILDERTEVERFFLD 365
S + L ++E Q+E+ ++ + + ++ + + + + E+ E +
Sbjct: 784 SAKVCLTDVTIMER--FQMELKDVERKIAQQAAKLQGIDLDRTVQQVNQEKQEKQH---- 837
Query: 366 ALHQVKQQILISRK 379
L V +I ++RK
Sbjct: 838 KLDTVSSKIELNRK 851
Score = 54.7 bits (130), Expect = 2e-07
Identities = 73/321 (22%), Positives = 135/321 (42%), Gaps = 58/321 (18%)
Query: 66 DLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIE--KLKQQLNETKEKAQEEKDKLEQKYTR 123
DL+ K + S S LKK+++ +D M+ ++Q + + KEK E Q R
Sbjct: 700 DLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLVPMRQSIIDLKEKEIPELRNKLQNVNR 759
Query: 124 QINELEGQFHQKAKEIGMIH----------TELKAVRQFQKRKIQVERELDDLKENLRNT 173
I L+ ++ +G I T++ + +FQ VER++ L+
Sbjct: 760 DIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGI 819
Query: 174 ERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQ 233
+ T++++ E++H+L+ + K ++LN R + ++ Q
Sbjct: 820 DL--DRTVQQVNQEKQEKQHKLDTVSSK--------------IELN---RKLIQD----Q 856
Query: 234 KALAYHLKETDALQKNSQKLQESHTLLLHQK-EINDLLVKEKIMQLVQQRSQIQTLQKKV 292
+ HLK T K S+KLQ S L Q+ E + + ++ L ++ I+ +++V
Sbjct: 857 QEQIQHLKSTTNELK-SEKLQISTNLQRRQQLEEQTVELSTEVQSLYRE---IKDAKEQV 912
Query: 293 VNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNI 352
LET L +E E + K +N + ++ DKL N +K+ KNI
Sbjct: 913 SPLETTLEKFQQEKEELINK-------KNTSNKIAQDKL-----------NDIKEKVKNI 954
Query: 353 LDERTEVERFFLDALHQVKQQ 373
++E + D K+Q
Sbjct: 955 HGYMKDIENYIQDGKDDYKKQ 975
Score = 54.3 bits (129), Expect = 3e-07
Identities = 75/347 (21%), Positives = 157/347 (45%), Gaps = 37/347 (10%)
Query: 56 TSRILAKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKD 115
+S+ + KS E+ K+I LS + K D E ++ K+Q+ + + +E+ +
Sbjct: 236 SSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEI-KALDSRKKQMEKDNSELEEKME 294
Query: 116 KLEQKYTRQINEL----EGQFHQKAKEIGMIHTELKAVRQ------FQKRKIQVER---- 161
K+ Q Q+N+L + +K +++ H EL+ + + +K ++ VE+
Sbjct: 295 KVFQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQ 354
Query: 162 -ELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLND 220
+ D +E++R + + Q +LE FE E++ + ++ ER EA + +
Sbjct: 355 LQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEGEA--KTAN 412
Query: 221 AGRNVFKENDYLQKALAYHLKETDALQKNSQ---KLQESHTLLLHQKEINDLLVKEKIMQ 277
N F E + L++ K+ D ++ ++ E + +L +K+ VK ++ Q
Sbjct: 413 QLMNDFAEKETLKQ------KQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQQ 466
Query: 278 LVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQM 337
L +I L ++++ E LS K E LK++ +I Q + ++D+ L+
Sbjct: 467 LEGSSDRILELDQELIKAERELSKAEKNSNVETLKME---VISLQNEKADLDR---TLRK 520
Query: 338 KDREMNRVKKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQI 384
D+EM ++ + RT++E D + +Q I +H ++
Sbjct: 521 LDQEMEQL----NHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDEL 563
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 64.7 bits (156), Expect = 2e-10
Identities = 82/418 (19%), Positives = 177/418 (42%), Gaps = 64/418 (15%)
Query: 83 SYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMI 142
+YLK ++ + + K+K L T+ QEE+ + ++ ++ E + + + KE+
Sbjct: 825 AYLKLRNWQWWRLFTKVKPLLQVTR---QEEEMQAKEDELQKTKERQQKAENELKELEQK 881
Query: 143 HTELKAVRQFQKRKIQVEREL----DDLKENLRNTERIHQETLRRLESRFFEEKHRLEQ- 197
H++L + + ++Q E EL ++++ L ++ +E L +E+R EE+ R +Q
Sbjct: 882 HSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL 941
Query: 198 EAEKK-----IIMLAERAHHE-----------------------AIVQLNDAGRNVFKEN 229
+AE+K ++ L E+ E I+ ++D + KE
Sbjct: 942 QAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER 1001
Query: 230 DYLQKA---LAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQ----- 281
L++ L +L E + KN KL+ H ++ + E+ L +EK Q +++
Sbjct: 1002 KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR-LKKEEKSRQELEKLKRKL 1060
Query: 282 -------RSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQA------GQVEI 328
QI LQ ++ L+ L+ +E ++ + +L +N A + I
Sbjct: 1061 EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1120
Query: 329 DKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAA 388
LQ L + N+ +K +++ +E ++ D L Q + K +++
Sbjct: 1121 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT--- 1177
Query: 389 FNLKMRAACTGRTEYPKIRTFDGREHSTNSVNQDLLEAEKWTHIEGNVDIGDLTWEQK 446
++ A T + + + R+ +V + + E++ + N+D T E++
Sbjct: 1178 ---VLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232
Score = 55.8 bits (133), Expect = 9e-08
Identities = 80/375 (21%), Positives = 160/375 (42%), Gaps = 43/375 (11%)
Query: 12 KSKGKDTKKLIKTDESVVDRAKANASLWE-ARLEVTELSRIKYRDTSRI------LAKSN 64
+ K K+ KL ES++ + E +R E+ +L R D S L
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 65 EDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQ 124
+LK + K E+++ + L+ L + +K+N ++K++ +L QE+ D ++ R
Sbjct: 1079 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR-ELEGHISDLQEDLD--SERAAR- 1134
Query: 125 INELEGQFHQKAKEIGMIHTELK----AVRQFQKRKIQVERELDDLKENLRNTERIHQET 180
N+ E Q +E+ + TEL+ + Q+ + + E+E+ LK+ L R H+
Sbjct: 1135 -NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1193
Query: 181 LRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHL 240
++ + + + L ++ E Q A N+ K L+K A
Sbjct: 1194 VQEMRQKHAQAVEELTEQLE----------------QFKRAKANLDKNKQTLEKENADLA 1237
Query: 241 KETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALS 300
E L + Q+++ L + ++ +L + K + R+++ K+ N +++
Sbjct: 1238 GELRVLGQAKQEVEHKKKKL--EAQVQEL--QSKCSDGERARAELNDKVHKLQNEVESVT 1293
Query: 301 YMTKEFESEVLKLQQH-AMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEV 359
M E E + +KL + A + +Q + Q LLQ + R+ V + + +ER +
Sbjct: 1294 GMLNEAEGKAIKLAKDVASLSSQ-----LQDTQELLQEETRQKLNVSTKLRQLEEERNSL 1348
Query: 360 ERFFLDALHQVKQQI 374
+ LD + KQ +
Sbjct: 1349 QD-QLDEEMEAKQNL 1362
Score = 50.1 bits (118), Expect = 5e-06
Identities = 96/447 (21%), Positives = 177/447 (39%), Gaps = 84/447 (18%)
Query: 6 KDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSN- 64
KD S+ +DT++L++ + R K N S +LE E + ++ + + AK N
Sbjct: 1308 KDVASLSSQLQDTQELLQEET----RQKLNVSTKLRQLE-EERNSLQDQLDEEMEAKQNL 1362
Query: 65 -----------EDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETK---EKA 110
D KKK +D S + L++ + IE L QQ E +K
Sbjct: 1363 ERHISTLNIQLSDSKKKL----QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
Query: 111 QEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENL 170
++ K++L+Q+ + +L+ Q RQ + +R+ D L
Sbjct: 1419 EKTKNRLQQELDDLVVDLDNQ------------------RQLVSNLEKKQRKFDQLLAEE 1460
Query: 171 RNTERIHQETLRRLESRFFEEKHRLEQEA---EKKIIMLAERAHHEAIVQLNDAGRNVFK 227
+N + S++ +E+ R E EA E K + LA RA EA+ +A + +
Sbjct: 1461 KN-----------ISSKYADERDRAEAEAREKETKALSLA-RALEEAL----EAKEELER 1504
Query: 228 ENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQT 287
N L+ + + D + KN +L++S L Q E E QL + ++Q
Sbjct: 1505 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME-------EMKTQLEELEDELQA 1557
Query: 288 LQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRV-- 345
+ + LE + + +FE ++ + E + Q++ ++ +++D R
Sbjct: 1558 TEDAKLRLEVNMQALKGQFERDLQARDEQN--EEKRRQLQRQLHEYETELEDERKQRALA 1615
Query: 346 ----KKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAACTGRT 401
KKL ++ D + + +KQ RK Q+ F ++ A R
Sbjct: 1616 AAAKKKLEGDLKDLELQADSAIKGREEAIKQ----LRKLQAQMKD--FQRELEDARASRD 1669
Query: 402 EYPKIRTFDGREHSTNSVNQDLLEAEK 428
E T E S+ DL++ ++
Sbjct: 1670 EI--FATAKENEKKAKSLEADLMQLQE 1694
Score = 46.6 bits (109), Expect = 6e-05
Identities = 85/422 (20%), Positives = 180/422 (42%), Gaps = 89/422 (21%)
Query: 6 KDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNE 65
+D+ + +++ K+TK L A+A EA+ E+ +++ + +++ S +
Sbjct: 1471 RDRAEAEAREKETKAL--------SLARALEEALEAKEELERTNKMLKAEMEDLVS-SKD 1521
Query: 66 DLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETK------------------ 107
D+ K ++EK + L+ Q +E +E+L+ +L T+
Sbjct: 1522 DVGKNVHELEKSKRA----LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFE 1577
Query: 108 -------EKAQEEKDKLEQKYTRQINELEGQFHQKA-------------KEIGM-----I 142
E+ +E++ +L+++ ELE + Q+A K++ + I
Sbjct: 1578 RDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI 1637
Query: 143 HTELKAVRQFQKRKIQV---ERELDD-----------LKENLRNTERIHQETLRRLESRF 188
+A++Q +K + Q+ +REL+D KEN + + + + ++ E
Sbjct: 1638 KGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLA 1697
Query: 189 FEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFK-ENDYLQKALAYHLKETDALQ 247
E+ R + + EK+ LAE + + +GRN + E L+ +A +E + Q
Sbjct: 1698 AAERARKQADLEKE--ELAEE------LASSLSGRNALQDEKRRLEARIAQLEEELEEEQ 1749
Query: 248 KNSQKLQESHTLLLHQKE--INDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYM--- 302
N + + + Q E N+L + Q + S Q L+++ L + L M
Sbjct: 1750 GNMEAMSDRVRKATQQAEQLSNELATERSTAQ--KNESARQQLERQNKELRSKLHEMEGA 1807
Query: 303 -TKEFESEVLKLQ-QHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVE 360
+F+S + L+ + A +E Q Q +K +K ++ ++K++ + DER E
Sbjct: 1808 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD-KKLKEILLQVEDERKMAE 1866
Query: 361 RF 362
++
Sbjct: 1867 QY 1868
Score = 34.7 bits (78), Expect = 0.22
Identities = 28/134 (20%), Positives = 65/134 (48%), Gaps = 10/134 (7%)
Query: 20 KLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDIM 79
KL + + +V + K+ + EA++ E + +R + + LK+K K+++ ++
Sbjct: 1800 KLHEMEGAVKSKFKSTIAALEAKIAQLEE---QVEQEAREKQAATKSLKQKDKKLKEILL 1856
Query: 80 SVLSYLKKQDQEKDNM------IEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFH 133
V K +Q K+ +++LK+QL E +E++Q +K R+++E
Sbjct: 1857 QVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINAN-RRKLQRELDEATESNE 1915
Query: 134 QKAKEIGMIHTELK 147
+E+ + ++L+
Sbjct: 1916 AMGREVNALKSKLR 1929
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 64.7 bits (156), Expect = 2e-10
Identities = 82/418 (19%), Positives = 177/418 (42%), Gaps = 64/418 (15%)
Query: 83 SYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMI 142
+YLK ++ + + K+K L T+ QEE+ + ++ ++ E + + + KE+
Sbjct: 832 AYLKLRNWQWWRLFTKVKPLLQVTR---QEEEMQAKEDELQKTKERQQKAENELKELEQK 888
Query: 143 HTELKAVRQFQKRKIQVEREL----DDLKENLRNTERIHQETLRRLESRFFEEKHRLEQ- 197
H++L + + ++Q E EL ++++ L ++ +E L +E+R EE+ R +Q
Sbjct: 889 HSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL 948
Query: 198 EAEKK-----IIMLAERAHHE-----------------------AIVQLNDAGRNVFKEN 229
+AE+K ++ L E+ E I+ ++D + KE
Sbjct: 949 QAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER 1008
Query: 230 DYLQKA---LAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQ----- 281
L++ L +L E + KN KL+ H ++ + E+ L +EK Q +++
Sbjct: 1009 KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR-LKKEEKSRQELEKLKRKL 1067
Query: 282 -------RSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQA------GQVEI 328
QI LQ ++ L+ L+ +E ++ + +L +N A + I
Sbjct: 1068 EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1127
Query: 329 DKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAA 388
LQ L + N+ +K +++ +E ++ D L Q + K +++
Sbjct: 1128 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT--- 1184
Query: 389 FNLKMRAACTGRTEYPKIRTFDGREHSTNSVNQDLLEAEKWTHIEGNVDIGDLTWEQK 446
++ A T + + + R+ +V + + E++ + N+D T E++
Sbjct: 1185 ---VLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1239
Score = 55.8 bits (133), Expect = 9e-08
Identities = 80/375 (21%), Positives = 160/375 (42%), Gaps = 43/375 (11%)
Query: 12 KSKGKDTKKLIKTDESVVDRAKANASLWE-ARLEVTELSRIKYRDTSRI------LAKSN 64
+ K K+ KL ES++ + E +R E+ +L R D S L
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 65 EDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQ 124
+LK + K E+++ + L+ L + +K+N ++K++ +L QE+ D ++ R
Sbjct: 1086 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR-ELEGHISDLQEDLD--SERAAR- 1141
Query: 125 INELEGQFHQKAKEIGMIHTELK----AVRQFQKRKIQVERELDDLKENLRNTERIHQET 180
N+ E Q +E+ + TEL+ + Q+ + + E+E+ LK+ L R H+
Sbjct: 1142 -NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1200
Query: 181 LRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHL 240
++ + + + L ++ E Q A N+ K L+K A
Sbjct: 1201 VQEMRQKHAQAVEELTEQLE----------------QFKRAKANLDKNKQTLEKENADLA 1244
Query: 241 KETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALS 300
E L + Q+++ L + ++ +L + K + R+++ K+ N +++
Sbjct: 1245 GELRVLGQAKQEVEHKKKKL--EAQVQEL--QSKCSDGERARAELNDKVHKLQNEVESVT 1300
Query: 301 YMTKEFESEVLKLQQH-AMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEV 359
M E E + +KL + A + +Q + Q LLQ + R+ V + + +ER +
Sbjct: 1301 GMLNEAEGKAIKLAKDVASLSSQ-----LQDTQELLQEETRQKLNVSTKLRQLEEERNSL 1355
Query: 360 ERFFLDALHQVKQQI 374
+ LD + KQ +
Sbjct: 1356 QD-QLDEEMEAKQNL 1369
Score = 50.1 bits (118), Expect = 5e-06
Identities = 96/447 (21%), Positives = 177/447 (39%), Gaps = 84/447 (18%)
Query: 6 KDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSN- 64
KD S+ +DT++L++ + R K N S +LE E + ++ + + AK N
Sbjct: 1315 KDVASLSSQLQDTQELLQEET----RQKLNVSTKLRQLE-EERNSLQDQLDEEMEAKQNL 1369
Query: 65 -----------EDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETK---EKA 110
D KKK +D S + L++ + IE L QQ E +K
Sbjct: 1370 ERHISTLNIQLSDSKKKL----QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1425
Query: 111 QEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENL 170
++ K++L+Q+ + +L+ Q RQ + +R+ D L
Sbjct: 1426 EKTKNRLQQELDDLVVDLDNQ------------------RQLVSNLEKKQRKFDQLLAEE 1467
Query: 171 RNTERIHQETLRRLESRFFEEKHRLEQEA---EKKIIMLAERAHHEAIVQLNDAGRNVFK 227
+N + S++ +E+ R E EA E K + LA RA EA+ +A + +
Sbjct: 1468 KN-----------ISSKYADERDRAEAEAREKETKALSLA-RALEEAL----EAKEELER 1511
Query: 228 ENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQT 287
N L+ + + D + KN +L++S L Q E E QL + ++Q
Sbjct: 1512 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME-------EMKTQLEELEDELQA 1564
Query: 288 LQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRV-- 345
+ + LE + + +FE ++ + E + Q++ ++ +++D R
Sbjct: 1565 TEDAKLRLEVNMQALKGQFERDLQARDEQN--EEKRRQLQRQLHEYETELEDERKQRALA 1622
Query: 346 ----KKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAACTGRT 401
KKL ++ D + + +KQ RK Q+ F ++ A R
Sbjct: 1623 AAAKKKLEGDLKDLELQADSAIKGREEAIKQ----LRKLQAQMKD--FQRELEDARASRD 1676
Query: 402 EYPKIRTFDGREHSTNSVNQDLLEAEK 428
E T E S+ DL++ ++
Sbjct: 1677 EI--FATAKENEKKAKSLEADLMQLQE 1701
Score = 46.6 bits (109), Expect = 6e-05
Identities = 85/422 (20%), Positives = 180/422 (42%), Gaps = 89/422 (21%)
Query: 6 KDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNE 65
+D+ + +++ K+TK L A+A EA+ E+ +++ + +++ S +
Sbjct: 1478 RDRAEAEAREKETKAL--------SLARALEEALEAKEELERTNKMLKAEMEDLVS-SKD 1528
Query: 66 DLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETK------------------ 107
D+ K ++EK + L+ Q +E +E+L+ +L T+
Sbjct: 1529 DVGKNVHELEKSKRA----LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFE 1584
Query: 108 -------EKAQEEKDKLEQKYTRQINELEGQFHQKA-------------KEIGM-----I 142
E+ +E++ +L+++ ELE + Q+A K++ + I
Sbjct: 1585 RDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI 1644
Query: 143 HTELKAVRQFQKRKIQV---ERELDD-----------LKENLRNTERIHQETLRRLESRF 188
+A++Q +K + Q+ +REL+D KEN + + + + ++ E
Sbjct: 1645 KGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLA 1704
Query: 189 FEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFK-ENDYLQKALAYHLKETDALQ 247
E+ R + + EK+ LAE + + +GRN + E L+ +A +E + Q
Sbjct: 1705 AAERARKQADLEKE--ELAEE------LASSLSGRNALQDEKRRLEARIAQLEEELEEEQ 1756
Query: 248 KNSQKLQESHTLLLHQKE--INDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYM--- 302
N + + + Q E N+L + Q + S Q L+++ L + L M
Sbjct: 1757 GNMEAMSDRVRKATQQAEQLSNELATERSTAQ--KNESARQQLERQNKELRSKLHEMEGA 1814
Query: 303 -TKEFESEVLKLQ-QHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVE 360
+F+S + L+ + A +E Q Q +K +K ++ ++K++ + DER E
Sbjct: 1815 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD-KKLKEILLQVEDERKMAE 1873
Query: 361 RF 362
++
Sbjct: 1874 QY 1875
Score = 34.7 bits (78), Expect = 0.22
Identities = 28/134 (20%), Positives = 65/134 (48%), Gaps = 10/134 (7%)
Query: 20 KLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDIM 79
KL + + +V + K+ + EA++ E + +R + + LK+K K+++ ++
Sbjct: 1807 KLHEMEGAVKSKFKSTIAALEAKIAQLEE---QVEQEAREKQAATKSLKQKDKKLKEILL 1863
Query: 80 SVLSYLKKQDQEKDNM------IEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFH 133
V K +Q K+ +++LK+QL E +E++Q +K R+++E
Sbjct: 1864 QVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINAN-RRKLQRELDEATESNE 1922
Query: 134 QKAKEIGMIHTELK 147
+E+ + ++L+
Sbjct: 1923 AMGREVNALKSKLR 1936
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 64.7 bits (156), Expect = 2e-10
Identities = 82/418 (19%), Positives = 177/418 (42%), Gaps = 64/418 (15%)
Query: 83 SYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMI 142
+YLK ++ + + K+K L T+ QEE+ + ++ ++ E + + + KE+
Sbjct: 832 AYLKLRNWQWWRLFTKVKPLLQVTR---QEEEMQAKEDELQKTKERQQKAENELKELEQK 888
Query: 143 HTELKAVRQFQKRKIQVEREL----DDLKENLRNTERIHQETLRRLESRFFEEKHRLEQ- 197
H++L + + ++Q E EL ++++ L ++ +E L +E+R EE+ R +Q
Sbjct: 889 HSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL 948
Query: 198 EAEKK-----IIMLAERAHHE-----------------------AIVQLNDAGRNVFKEN 229
+AE+K ++ L E+ E I+ ++D + KE
Sbjct: 949 QAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER 1008
Query: 230 DYLQKA---LAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQ----- 281
L++ L +L E + KN KL+ H ++ + E+ L +EK Q +++
Sbjct: 1009 KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR-LKKEEKSRQELEKLKRKL 1067
Query: 282 -------RSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQA------GQVEI 328
QI LQ ++ L+ L+ +E ++ + +L +N A + I
Sbjct: 1068 EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1127
Query: 329 DKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAA 388
LQ L + N+ +K +++ +E ++ D L Q + K +++
Sbjct: 1128 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT--- 1184
Query: 389 FNLKMRAACTGRTEYPKIRTFDGREHSTNSVNQDLLEAEKWTHIEGNVDIGDLTWEQK 446
++ A T + + + R+ +V + + E++ + N+D T E++
Sbjct: 1185 ---VLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1239
Score = 55.8 bits (133), Expect = 9e-08
Identities = 80/375 (21%), Positives = 160/375 (42%), Gaps = 43/375 (11%)
Query: 12 KSKGKDTKKLIKTDESVVDRAKANASLWE-ARLEVTELSRIKYRDTSRI------LAKSN 64
+ K K+ KL ES++ + E +R E+ +L R D S L
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 65 EDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQ 124
+LK + K E+++ + L+ L + +K+N ++K++ +L QE+ D ++ R
Sbjct: 1086 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR-ELEGHISDLQEDLD--SERAAR- 1141
Query: 125 INELEGQFHQKAKEIGMIHTELK----AVRQFQKRKIQVERELDDLKENLRNTERIHQET 180
N+ E Q +E+ + TEL+ + Q+ + + E+E+ LK+ L R H+
Sbjct: 1142 -NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1200
Query: 181 LRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHL 240
++ + + + L ++ E Q A N+ K L+K A
Sbjct: 1201 VQEMRQKHAQAVEELTEQLE----------------QFKRAKANLDKNKQTLEKENADLA 1244
Query: 241 KETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALS 300
E L + Q+++ L + ++ +L + K + R+++ K+ N +++
Sbjct: 1245 GELRVLGQAKQEVEHKKKKL--EAQVQEL--QSKCSDGERARAELNDKVHKLQNEVESVT 1300
Query: 301 YMTKEFESEVLKLQQH-AMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEV 359
M E E + +KL + A + +Q + Q LLQ + R+ V + + +ER +
Sbjct: 1301 GMLNEAEGKAIKLAKDVASLSSQ-----LQDTQELLQEETRQKLNVSTKLRQLEEERNSL 1355
Query: 360 ERFFLDALHQVKQQI 374
+ LD + KQ +
Sbjct: 1356 QD-QLDEEMEAKQNL 1369
Score = 50.1 bits (118), Expect = 5e-06
Identities = 96/447 (21%), Positives = 177/447 (39%), Gaps = 84/447 (18%)
Query: 6 KDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSN- 64
KD S+ +DT++L++ + R K N S +LE E + ++ + + AK N
Sbjct: 1315 KDVASLSSQLQDTQELLQEET----RQKLNVSTKLRQLE-EERNSLQDQLDEEMEAKQNL 1369
Query: 65 -----------EDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETK---EKA 110
D KKK +D S + L++ + IE L QQ E +K
Sbjct: 1370 ERHISTLNIQLSDSKKKL----QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1425
Query: 111 QEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENL 170
++ K++L+Q+ + +L+ Q RQ + +R+ D L
Sbjct: 1426 EKTKNRLQQELDDLVVDLDNQ------------------RQLVSNLEKKQRKFDQLLAEE 1467
Query: 171 RNTERIHQETLRRLESRFFEEKHRLEQEA---EKKIIMLAERAHHEAIVQLNDAGRNVFK 227
+N + S++ +E+ R E EA E K + LA RA EA+ +A + +
Sbjct: 1468 KN-----------ISSKYADERDRAEAEAREKETKALSLA-RALEEAL----EAKEELER 1511
Query: 228 ENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQT 287
N L+ + + D + KN +L++S L Q E E QL + ++Q
Sbjct: 1512 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME-------EMKTQLEELEDELQA 1564
Query: 288 LQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRV-- 345
+ + LE + + +FE ++ + E + Q++ ++ +++D R
Sbjct: 1565 TEDAKLRLEVNMQALKGQFERDLQARDEQN--EEKRRQLQRQLHEYETELEDERKQRALA 1622
Query: 346 ----KKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAACTGRT 401
KKL ++ D + + +KQ RK Q+ F ++ A R
Sbjct: 1623 AAAKKKLEGDLKDLELQADSAIKGREEAIKQ----LRKLQAQMKD--FQRELEDARASRD 1676
Query: 402 EYPKIRTFDGREHSTNSVNQDLLEAEK 428
E T E S+ DL++ ++
Sbjct: 1677 EI--FATAKENEKKAKSLEADLMQLQE 1701
Score = 46.6 bits (109), Expect = 6e-05
Identities = 85/422 (20%), Positives = 180/422 (42%), Gaps = 89/422 (21%)
Query: 6 KDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNE 65
+D+ + +++ K+TK L A+A EA+ E+ +++ + +++ S +
Sbjct: 1478 RDRAEAEAREKETKAL--------SLARALEEALEAKEELERTNKMLKAEMEDLVS-SKD 1528
Query: 66 DLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETK------------------ 107
D+ K ++EK + L+ Q +E +E+L+ +L T+
Sbjct: 1529 DVGKNVHELEKSKRA----LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFE 1584
Query: 108 -------EKAQEEKDKLEQKYTRQINELEGQFHQKA-------------KEIGM-----I 142
E+ +E++ +L+++ ELE + Q+A K++ + I
Sbjct: 1585 RDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI 1644
Query: 143 HTELKAVRQFQKRKIQV---ERELDD-----------LKENLRNTERIHQETLRRLESRF 188
+A++Q +K + Q+ +REL+D KEN + + + + ++ E
Sbjct: 1645 KGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLA 1704
Query: 189 FEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFK-ENDYLQKALAYHLKETDALQ 247
E+ R + + EK+ LAE + + +GRN + E L+ +A +E + Q
Sbjct: 1705 AAERARKQADLEKE--ELAEE------LASSLSGRNALQDEKRRLEARIAQLEEELEEEQ 1756
Query: 248 KNSQKLQESHTLLLHQKE--INDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYM--- 302
N + + + Q E N+L + Q + S Q L+++ L + L M
Sbjct: 1757 GNMEAMSDRVRKATQQAEQLSNELATERSTAQ--KNESARQQLERQNKELRSKLHEMEGA 1814
Query: 303 -TKEFESEVLKLQ-QHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVE 360
+F+S + L+ + A +E Q Q +K +K ++ ++K++ + DER E
Sbjct: 1815 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD-KKLKEILLQVEDERKMAE 1873
Query: 361 RF 362
++
Sbjct: 1874 QY 1875
Score = 34.7 bits (78), Expect = 0.22
Identities = 28/134 (20%), Positives = 65/134 (48%), Gaps = 10/134 (7%)
Query: 20 KLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDIM 79
KL + + +V + K+ + EA++ E + +R + + LK+K K+++ ++
Sbjct: 1807 KLHEMEGAVKSKFKSTIAALEAKIAQLEE---QVEQEAREKQAATKSLKQKDKKLKEILL 1863
Query: 80 SVLSYLKKQDQEKDNM------IEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFH 133
V K +Q K+ +++LK+QL E +E++Q +K R+++E
Sbjct: 1864 QVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINAN-RRKLQRELDEATESNE 1922
Query: 134 QKAKEIGMIHTELK 147
+E+ + ++L+
Sbjct: 1923 AMGREVNALKSKLR 1936
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 64.7 bits (156), Expect = 2e-10
Identities = 82/418 (19%), Positives = 177/418 (42%), Gaps = 64/418 (15%)
Query: 83 SYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMI 142
+YLK ++ + + K+K L T+ QEE+ + ++ ++ E + + + KE+
Sbjct: 825 AYLKLRNWQWWRLFTKVKPLLQVTR---QEEEMQAKEDELQKTKERQQKAENELKELEQK 881
Query: 143 HTELKAVRQFQKRKIQVEREL----DDLKENLRNTERIHQETLRRLESRFFEEKHRLEQ- 197
H++L + + ++Q E EL ++++ L ++ +E L +E+R EE+ R +Q
Sbjct: 882 HSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL 941
Query: 198 EAEKK-----IIMLAERAHHE-----------------------AIVQLNDAGRNVFKEN 229
+AE+K ++ L E+ E I+ ++D + KE
Sbjct: 942 QAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER 1001
Query: 230 DYLQKA---LAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQ----- 281
L++ L +L E + KN KL+ H ++ + E+ L +EK Q +++
Sbjct: 1002 KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR-LKKEEKSRQELEKLKRKL 1060
Query: 282 -------RSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQA------GQVEI 328
QI LQ ++ L+ L+ +E ++ + +L +N A + I
Sbjct: 1061 EGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1120
Query: 329 DKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAA 388
LQ L + N+ +K +++ +E ++ D L Q + K +++
Sbjct: 1121 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT--- 1177
Query: 389 FNLKMRAACTGRTEYPKIRTFDGREHSTNSVNQDLLEAEKWTHIEGNVDIGDLTWEQK 446
++ A T + + + R+ +V + + E++ + N+D T E++
Sbjct: 1178 ---VLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232
Score = 55.8 bits (133), Expect = 9e-08
Identities = 80/375 (21%), Positives = 160/375 (42%), Gaps = 43/375 (11%)
Query: 12 KSKGKDTKKLIKTDESVVDRAKANASLWE-ARLEVTELSRIKYRDTSRI------LAKSN 64
+ K K+ KL ES++ + E +R E+ +L R D S L
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 65 EDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQ 124
+LK + K E+++ + L+ L + +K+N ++K++ +L QE+ D ++ R
Sbjct: 1079 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR-ELEGHISDLQEDLD--SERAAR- 1134
Query: 125 INELEGQFHQKAKEIGMIHTELK----AVRQFQKRKIQVERELDDLKENLRNTERIHQET 180
N+ E Q +E+ + TEL+ + Q+ + + E+E+ LK+ L R H+
Sbjct: 1135 -NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1193
Query: 181 LRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHL 240
++ + + + L ++ E Q A N+ K L+K A
Sbjct: 1194 VQEMRQKHAQAVEELTEQLE----------------QFKRAKANLDKNKQTLEKENADLA 1237
Query: 241 KETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALS 300
E L + Q+++ L + ++ +L + K + R+++ K+ N +++
Sbjct: 1238 GELRVLGQAKQEVEHKKKKL--EAQVQEL--QSKCSDGERARAELNDKVHKLQNEVESVT 1293
Query: 301 YMTKEFESEVLKLQQH-AMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEV 359
M E E + +KL + A + +Q + Q LLQ + R+ V + + +ER +
Sbjct: 1294 GMLNEAEGKAIKLAKDVASLSSQ-----LQDTQELLQEETRQKLNVSTKLRQLEEERNSL 1348
Query: 360 ERFFLDALHQVKQQI 374
+ LD + KQ +
Sbjct: 1349 QD-QLDEEMEAKQNL 1362
Score = 50.1 bits (118), Expect = 5e-06
Identities = 96/447 (21%), Positives = 177/447 (39%), Gaps = 84/447 (18%)
Query: 6 KDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSN- 64
KD S+ +DT++L++ + R K N S +LE E + ++ + + AK N
Sbjct: 1308 KDVASLSSQLQDTQELLQEET----RQKLNVSTKLRQLE-EERNSLQDQLDEEMEAKQNL 1362
Query: 65 -----------EDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETK---EKA 110
D KKK +D S + L++ + IE L QQ E +K
Sbjct: 1363 ERHISTLNIQLSDSKKKL----QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
Query: 111 QEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENL 170
++ K++L+Q+ + +L+ Q RQ + +R+ D L
Sbjct: 1419 EKTKNRLQQELDDLVVDLDNQ------------------RQLVSNLEKKQRKFDQLLAEE 1460
Query: 171 RNTERIHQETLRRLESRFFEEKHRLEQEA---EKKIIMLAERAHHEAIVQLNDAGRNVFK 227
+N + S++ +E+ R E EA E K + LA RA EA+ +A + +
Sbjct: 1461 KN-----------ISSKYADERDRAEAEAREKETKALSLA-RALEEAL----EAKEELER 1504
Query: 228 ENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQT 287
N L+ + + D + KN +L++S L Q E E QL + ++Q
Sbjct: 1505 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME-------EMKTQLEELEDELQA 1557
Query: 288 LQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRV-- 345
+ + LE + + +FE ++ + E + Q++ ++ +++D R
Sbjct: 1558 TEDAKLRLEVNMQALKGQFERDLQARDEQN--EEKRRQLQRQLHEYETELEDERKQRALA 1615
Query: 346 ----KKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAACTGRT 401
KKL ++ D + + +KQ RK Q+ F ++ A R
Sbjct: 1616 AAAKKKLEGDLKDLELQADSAIKGREEAIKQ----LRKLQAQMKD--FQRELEDARASRD 1669
Query: 402 EYPKIRTFDGREHSTNSVNQDLLEAEK 428
E T E S+ DL++ ++
Sbjct: 1670 EI--FATAKENEKKAKSLEADLMQLQE 1694
Score = 46.6 bits (109), Expect = 6e-05
Identities = 85/422 (20%), Positives = 180/422 (42%), Gaps = 89/422 (21%)
Query: 6 KDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNE 65
+D+ + +++ K+TK L A+A EA+ E+ +++ + +++ S +
Sbjct: 1471 RDRAEAEAREKETKAL--------SLARALEEALEAKEELERTNKMLKAEMEDLVS-SKD 1521
Query: 66 DLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETK------------------ 107
D+ K ++EK + L+ Q +E +E+L+ +L T+
Sbjct: 1522 DVGKNVHELEKSKRA----LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFE 1577
Query: 108 -------EKAQEEKDKLEQKYTRQINELEGQFHQKA-------------KEIGM-----I 142
E+ +E++ +L+++ ELE + Q+A K++ + I
Sbjct: 1578 RDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI 1637
Query: 143 HTELKAVRQFQKRKIQV---ERELDD-----------LKENLRNTERIHQETLRRLESRF 188
+A++Q +K + Q+ +REL+D KEN + + + + ++ E
Sbjct: 1638 KGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLA 1697
Query: 189 FEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFK-ENDYLQKALAYHLKETDALQ 247
E+ R + + EK+ LAE + + +GRN + E L+ +A +E + Q
Sbjct: 1698 AAERARKQADLEKE--ELAEE------LASSLSGRNALQDEKRRLEARIAQLEEELEEEQ 1749
Query: 248 KNSQKLQESHTLLLHQKE--INDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYM--- 302
N + + + Q E N+L + Q + S Q L+++ L + L M
Sbjct: 1750 GNMEAMSDRVRKATQQAEQLSNELATERSTAQ--KNESARQQLERQNKELRSKLHEMEGA 1807
Query: 303 -TKEFESEVLKLQ-QHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVE 360
+F+S + L+ + A +E Q Q +K +K ++ ++K++ + DER E
Sbjct: 1808 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD-KKLKEILLQVEDERKMAE 1866
Query: 361 RF 362
++
Sbjct: 1867 QY 1868
Score = 34.7 bits (78), Expect = 0.22
Identities = 28/134 (20%), Positives = 65/134 (48%), Gaps = 10/134 (7%)
Query: 20 KLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDIM 79
KL + + +V + K+ + EA++ E + +R + + LK+K K+++ ++
Sbjct: 1800 KLHEMEGAVKSKFKSTIAALEAKIAQLEE---QVEQEAREKQAATKSLKQKDKKLKEILL 1856
Query: 80 SVLSYLKKQDQEKDNM------IEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFH 133
V K +Q K+ +++LK+QL E +E++Q +K R+++E
Sbjct: 1857 QVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINAN-RRKLQRELDEATESNE 1915
Query: 134 QKAKEIGMIHTELK 147
+E+ + ++L+
Sbjct: 1916 AMGREVNALKSKLR 1929
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.343
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,599,493
Number of Sequences: 37866
Number of extensions: 773627
Number of successful extensions: 10518
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 283
Number of HSP's successfully gapped in prelim test: 1067
Number of HSP's that attempted gapping in prelim test: 4889
Number of HSP's gapped (non-prelim): 3889
length of query: 529
length of database: 18,247,518
effective HSP length: 107
effective length of query: 422
effective length of database: 14,195,856
effective search space: 5990651232
effective search space used: 5990651232
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.