Guide to the Human Genome
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Name: CHEK1 Sequence: fasta or formatted (476aa) NCBI GI: 166295194
Description:

checkpoint kinase 1

Referenced in:

DNases, Recombination, and DNA Repair
Additional Serine / Threonine Protein Kinases

Other entries for this name:
alt mRNA [476aa] checkpoint kinase 1
alt mRNA [476aa] checkpoint kinase 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.2         20           1
 C cysteine            2.1         10           1
 D aspartate           6.3         30           2
 E glutamate           6.5         31           2
 F phenylalanine       3.8         18           2
 G glycine             5.7         27           2
 H histidine           2.1         10           1
 I isoleucine          5.7         27           1
 K lysine              8.6         41           2
 L leucine            10.3         49           3
 M methionine          2.3         11           1
 N asparagine          4.8         23           2
 P proline             5.7         27           1
 Q glutamine           3.8         18           1
 R arginine            5.3         25           2
 S serine              7.4         35           3
 T threonine           4.2         20           2
 V valine              6.3         30           2
 W tryptophan          2.1         10           1
 Y tyrosine            2.9         14           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   checkpoint kinase 1 
CHEK1                 1.000   checkpoint kinase 1 
CHEK1                 1.000   checkpoint kinase 1 
MARK2                 0.156   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.156   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.156   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.156   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.156   MAP/microtubule affinity-regulating kinase 2 isoform...
MARK1                 0.149   MAP/microtubule affinity-regulating kinase 1 
MARK3                 0.149   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.149   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.149   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.149   MAP/microtubule affinity-regulating kinase 3 isoform...
MARK4                 0.148   MAP/microtubule affinity-regulating kinase 4 
SIK2                  0.146   SNF1-like kinase 2 
BRSK1                 0.145   BR serine/threonine kinase 1 
BRSK2                 0.142   BR serine/threonine kinase 2 
MELK                  0.142   maternal embryonic leucine zipper kinase 
SIK1                  0.141   SNF1-like kinase 
PRKAA1                0.139   protein kinase, AMP-activated, alpha 1 catalytic sub...
PRKAA2                0.136   AMP-activated protein kinase alpha 2 catalytic subun...
QSK                   0.135   serine/threonine-protein kinase QSK 
HUNK                  0.132   hormonally upregulated Neu-associated kinase 
PRKAA1                0.131   protein kinase, AMP-activated, alpha 1 catalytic sub...
NUAK1                 0.129   AMPK-related protein kinase 5 
CAMK1D                0.125   calcium/calmodulin-dependent protein kinase ID isofor...
CAMK1D                0.125   calcium/calmodulin-dependent protein kinase ID isofo...
DCLK3                 0.123   doublecortin-like kinase 3 
CHEK2                 0.121   protein kinase CHK2 isoform c 
CHEK2                 0.121   protein kinase CHK2 isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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