Guide to the Human Genome
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Search of human proteins with 166295179

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|166295179 ELG protein isoform a [Homo sapiens]
         (620 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|166295179 ELG protein isoform a [Homo sapiens]                    1222   0.0  
gi|8923771 ELG protein isoform b [Homo sapiens]                       676   0.0  
gi|210032580 SET domain containing 1B [Homo sapiens]                   54   4e-07
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           54   6e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    52   1e-06
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]           52   2e-06
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    52   2e-06
gi|17975763 myelin transcription factor 1 [Homo sapiens]               51   4e-06
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    51   4e-06
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    51   4e-06
gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo s...    50   5e-06
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    50   6e-06
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    50   6e-06
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           49   1e-05
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     49   2e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     49   2e-05
gi|33391150 nucleoplasmin 2 [Homo sapiens]                             49   2e-05
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    48   2e-05
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    48   2e-05
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    48   2e-05
gi|122937227 U2-associated SR140 protein [Homo sapiens]                48   2e-05
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    48   3e-05
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    48   3e-05
gi|5803109 osteosarcoma amplified 9 isoform 1 precursor [Homo sa...    47   5e-05
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap...    47   5e-05
gi|13376339 plasticity-related protein 2 [Homo sapiens]                47   5e-05
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           47   5e-05
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        47   7e-05
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    47   7e-05
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]              47   7e-05

>gi|166295179 ELG protein isoform a [Homo sapiens]
          Length = 620

 Score = 1222 bits (3162), Expect = 0.0
 Identities = 620/620 (100%), Positives = 620/620 (100%)

Query: 1   MAAVRGLRVSVKAEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRRSLKELI 60
           MAAVRGLRVSVKAEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRRSLKELI
Sbjct: 1   MAAVRGLRVSVKAEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRRSLKELI 60

Query: 61  PDTSRRYENKAGSFITGIDVTSKEAIEKKEQRAKRFHFRSEVNLAQRNVALDRDMMKKAI 120
           PDTSRRYENKAGSFITGIDVTSKEAIEKKEQRAKRFHFRSEVNLAQRNVALDRDMMKKAI
Sbjct: 61  PDTSRRYENKAGSFITGIDVTSKEAIEKKEQRAKRFHFRSEVNLAQRNVALDRDMMKKAI 120

Query: 121 PKVRLETIYICGVDEMSTQDVFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSS 180
           PKVRLETIYICGVDEMSTQDVFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSS
Sbjct: 121 PKVRLETIYICGVDEMSTQDVFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSS 180

Query: 181 LPAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEES 240
           LPAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEES
Sbjct: 181 LPAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEES 240

Query: 241 LLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWK 300
           LLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWK
Sbjct: 241 LLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWK 300

Query: 301 RRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEED 360
           RRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEED
Sbjct: 301 RRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEED 360

Query: 361 QDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSM 420
           QDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSM
Sbjct: 361 QDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSM 420

Query: 421 KMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPR 480
           KMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPR
Sbjct: 421 KMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPR 480

Query: 481 PPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREK 540
           PPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREK
Sbjct: 481 PPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREK 540

Query: 541 KSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLDN 600
           KSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLDN
Sbjct: 541 KSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLDN 600

Query: 601 LPSLQIEVSRESSSGSEAES 620
           LPSLQIEVSRESSSGSEAES
Sbjct: 601 LPSLQIEVSRESSSGSEAES 620


>gi|8923771 ELG protein isoform b [Homo sapiens]
          Length = 340

 Score =  676 bits (1744), Expect = 0.0
 Identities = 340/340 (100%), Positives = 340/340 (100%)

Query: 281 MKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPE 340
           MKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPE
Sbjct: 1   MKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPE 60

Query: 341 EPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSD 400
           EPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSD
Sbjct: 61  EPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSD 120

Query: 401 EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPP 460
           EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPP
Sbjct: 121 EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPP 180

Query: 461 EKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH 520
           EKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH
Sbjct: 181 EKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH 240

Query: 521 SRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRA 580
           SRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRA
Sbjct: 241 SRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRA 300

Query: 581 WGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES 620
           WGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES
Sbjct: 301 WGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES 340


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 37/109 (33%), Positives = 54/109 (49%), Gaps = 14/109 (12%)

Query: 337  NVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERS--------- 387
            ++ EE    EEEEE EEEEEEE+D D D+DDR   E  +E  AL +  E+          
Sbjct: 1040 SLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEET 1099

Query: 388  ----ASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQ 432
                 S+  + SSS+S E   + E    S+PS  +  +  +  +E E +
Sbjct: 1100 VSIVTSKAEATSSSESSESS-EFESSSESSPSSSEDEEEVVAREEEEEE 1147



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 40/172 (23%), Positives = 68/172 (39%), Gaps = 34/172 (19%)

Query: 344  EEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMD 403
            E+EEE    EEEEEEE+++M A++ +     E+     +     A+    A + DS  M+
Sbjct: 1133 EDEEEVVAREEEEEEEEEEMVAEESMASAGPEDF----EQDGEEAALAPGAPAVDSLGME 1188

Query: 404  YDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKF 463
             ++++                   E E+     R SM  +      ++    ++ PPE+ 
Sbjct: 1189 EEVDI-------------------ETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEE- 1228

Query: 464  ADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREP 515
                 L  E      P PP    ++       + P SPE+A   +  V  EP
Sbjct: 1229 ---PGLSQEGAMLLSPEPPAKEVEA-------RPPLSPERAPEHDLEVEPEP 1270



 Score = 33.9 bits (76), Expect = 0.46
 Identities = 13/48 (27%), Positives = 30/48 (62%)

Query: 192  ASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239
            + E +S E+ ++ ++E+  +DD+ ++ +  DE+ +D E   LS+  E+
Sbjct: 1042 SEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEK 1089



 Score = 29.6 bits (65), Expect = 8.6
 Identities = 13/55 (23%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 184  QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEE 238
            ++ +     S ++  E  +++++ED  DDD  +  E E+++  D  L   S+ +E
Sbjct: 1038 KESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDD-EDTALSEASEKDE 1091



 Score = 29.6 bits (65), Expect = 8.6
 Identities = 15/59 (25%), Positives = 30/59 (50%)

Query: 183  AQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESL 241
            ++++  + +  E +  E+ + D  +DS D DE+E  + +   S   E D     EEE++
Sbjct: 1042 SEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETV 1100


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 47/196 (23%), Positives = 88/196 (44%), Gaps = 11/196 (5%)

Query: 314 KKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEY 373
           KK+   G  VG  S       L  V ++  E EEE+E+E+  + + D+D D DD  + +Y
Sbjct: 130 KKKKYRGKAVGPASI------LKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKY 183

Query: 374 HEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQL 433
           + +    +   ++ ++RRS + S  S            S+ S  +S   +  + +  S+ 
Sbjct: 184 NLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRS 243

Query: 434 KNIRNSMRADSVSSSNIKNRIGNKLPPEK-FADVRHLLDEKRQHSRPRPPVSSTKSDIRQ 492
            +   S    S S S+ ++  G+  P ++ ++      +  R+ SR R    S+ S  R+
Sbjct: 244 SSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSR----SSSSGDRK 299

Query: 493 RLGKRPHSPEKAFSSN 508
           +   R  SPE+   S+
Sbjct: 300 KRRTRSRSPERRHRSS 315



 Score = 30.0 bits (66), Expect = 6.6
 Identities = 48/206 (23%), Positives = 75/206 (36%), Gaps = 35/206 (16%)

Query: 194 EDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLRNDLRPANKLA 253
           EDK +E  ++D+ ED S   + +  E EDE+ +D+    L   EEE         +NK  
Sbjct: 149 EDKESEGEEEDEDEDLS---KYKLDEDEDEDDADLSKYNLDASEEED--------SNK-K 196

Query: 254 KGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVI 313
           K NR   R  +K       ++ RS       + +    +   S+  + R  SR   R   
Sbjct: 197 KSNR---RSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRS-- 251

Query: 314 KKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEY 373
                 G     +S  HR S   + P +          E   +    +   + DR     
Sbjct: 252 -----RGSKSRSSSRSHRGS---SSPRKRSYSSSSSSPERNRKRSRSRSSSSGDR----- 298

Query: 374 HEELPALKQPRERSASRRSSASSSDS 399
                  ++ R RS  RR  +SS  S
Sbjct: 299 -----KKRRTRSRSPERRHRSSSGSS 319


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 27/72 (37%), Positives = 39/72 (54%)

Query: 336 VNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSAS 395
           +N  +E  EEEEEEEEEEEEEEEE++D + ++    EY EE    ++  E          
Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGEL 942

Query: 396 SSDSDEMDYDLE 407
             + +E D + E
Sbjct: 943 EEEEEEEDEEEE 954



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 23/68 (33%), Positives = 36/68 (52%)

Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDS 399
           EE  EEEEEEEEEEEEEE+ +++ + ++    E  EE    ++  E            + 
Sbjct: 891 EEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEED 950

Query: 400 DEMDYDLE 407
           +E + +LE
Sbjct: 951 EEEEEELE 958



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 1/68 (1%)

Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDS 399
           EE  EEEEEEE+ EEEEE+E++  + ++    E+ EE    +   E            + 
Sbjct: 898 EEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEEL 957

Query: 400 DEMDYDLE 407
           +E++ DLE
Sbjct: 958 EEVE-DLE 964



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 16/34 (47%), Positives = 25/34 (73%)

Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEY 373
           EE  EEEE E EEEEEEE+E+++ + ++   +E+
Sbjct: 932 EEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEF 965



 Score = 33.5 bits (75), Expect = 0.60
 Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 2/67 (2%)

Query: 175 LINMSSLPAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDE--AEEGEVEDENSSDVELDT 232
           +IN++S   +++    +  E++  E+ ++D +E+  D++E   EE E E+E   + E + 
Sbjct: 880 VININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEE 939

Query: 233 LSQVEEE 239
               EEE
Sbjct: 940 GELEEEE 946


>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
          Length = 320

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 46/190 (24%), Positives = 85/190 (44%), Gaps = 11/190 (5%)

Query: 314 KKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEY 373
           KK+   G  VG  S       L  V ++  E EEE+E+E+  + + D+D D DD  + +Y
Sbjct: 130 KKKKYRGKAVGPASI------LKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKY 183

Query: 374 HEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQL 433
           + +    +   ++ ++RRS + S  S            S+ S  +S   +  + +  S+ 
Sbjct: 184 NLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRS 243

Query: 434 KNIRNSMRADSVSSSNIKNRIGNKLPPEK-FADVRHLLDEKRQHSRPRPPVSSTKSDIRQ 492
            +   S    S S S+ ++  G+  P ++ ++      +  R+ SR R    S+ S  R+
Sbjct: 244 SSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSR----SSSSGDRK 299

Query: 493 RLGKRPHSPE 502
           +   R  SPE
Sbjct: 300 KRRTRSRSPE 309


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 61/239 (25%), Positives = 95/239 (39%), Gaps = 38/239 (15%)

Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVV----EYHEELPALK-------QPRERSA 388
           EE  EEEEEEEE++EEEE +D+   + +  ++    E  EE+P +K       +P+ RS 
Sbjct: 270 EEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQ 329

Query: 389 SRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSS 448
            +              +     ++    +K MK T   +E E ++K           SS 
Sbjct: 330 EQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIK-----------SSQ 378

Query: 449 NIKNRIGNKLPPEKFADVRH----LLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKA 504
            +K +  +  PP    D +      L E+       PP   TK         + HS E+ 
Sbjct: 379 GLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPPPHPQLHSEEEI 438

Query: 505 FSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKKSGNLWTRL--GSAPKTKEKNTK 561
               P+    P+  V  +L  P  D     ADTRE        +L  G +P +   +TK
Sbjct: 439 ---EPM--EGPAPPVLIQLSPPNTD-----ADTRELLVSQHTVQLVGGLSPLSSPSDTK 487



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 102/507 (20%), Positives = 186/507 (36%), Gaps = 97/507 (19%)

Query: 171 ATRALINMSSLPAQDK------IRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDEN 224
           A  A ++  S PA+++       R+     D++ +  +++++E+  ++D+ EE E +DE 
Sbjct: 234 ARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEE-EGDDEG 292

Query: 225 SSDVELDTLSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKEL----GAARRSQYY 280
               E   L + +EE      ++P   + +      R  T+  ++E+    G   RSQ  
Sbjct: 293 QKSREAPILKEFKEEGEEIPRVKPEEMMDE------RPKTRSQEQEVLERGGRFTRSQEE 346

Query: 281 MKYGNPNYGGMKGILSNSWKRRYHSRRIQRDV-IKKRALIGDDVGLTSYKHRHSGLVNVP 339
            +  +      +  +  +       R I+    +K+++       LT  + + S LV +P
Sbjct: 347 ARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKAS-LVALP 405

Query: 340 EEPIEEEE--------------------EEEEEEEEE--------EEEDQDMDADDR-VV 370
           E+   EEE                     EEE E  E        +    + DAD R ++
Sbjct: 406 EQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEPMEGPAPPVLIQLSPPNTDADTRELL 465

Query: 371 VEYH------------------EELPALKQPRERSASRRSSASSSD-SDEMDYDLELKMI 411
           V  H                   E PA K P E        ++ +D S + D + E    
Sbjct: 466 VSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEESVLPLVQKSTLADYSAQKDLEPESDRS 525

Query: 412 STPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLD 471
           + P P K  ++ +     E  LK      +    +S  +      K   +  +       
Sbjct: 526 AQPLPLKIEELALAKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSS 585

Query: 472 EKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSK 531
                SR R P SS         G R HSP ++   +    R  ++      G P+  S+
Sbjct: 586 SSSSRSRSRSPDSS---------GSRSHSPLRSKQRDVAQARTHANP----RGRPKMGSR 632

Query: 532 GLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQS 591
                T E +S     R  S  ++   N++K    +PG   D S       +  + K+ S
Sbjct: 633 ----STSESRS-----RSRSRSRSASSNSRK--SLSPGVSRDSST------SYTETKDPS 675

Query: 592 RQKKSRLDNLPSLQIEVSRESSSGSEA 618
             ++     +P LQ+   +E +S S +
Sbjct: 676 SGQEVATPPVPQLQVCEPKERTSTSSS 702



 Score = 30.0 bits (66), Expect = 6.6
 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 6/85 (7%)

Query: 338  VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRE----RSASRRSS 393
            VP E  E  + EEEEEE+E E +  +    +V VE     PA  + ++     + +RRS 
Sbjct: 925  VPAEGQENGQREEEEEEKEPEAEPPV--PPQVSVEVALPPPAEHEVKKVTLGDTLTRRSI 982

Query: 394  ASSSDSDEMDYDLELKMISTPSPKK 418
            +       +  D  ++    PSP +
Sbjct: 983  SQQKSGVSITIDDPVRTAQVPSPPR 1007



 Score = 29.6 bits (65), Expect = 8.6
 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 7/57 (12%)

Query: 344  EEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSD 400
            EEEE++E E+E E E ++ ++ + R   E+  E     + RER   R       D D
Sbjct: 1256 EEEEQKEREKEAERERNRQLEREKR--REHSRE-----RDRERERERERDRGDRDRD 1305


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 3/126 (2%)

Query: 331 RHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASR 390
           +  G+++  EE  EEEEEEEEEEE+EEEE+++ + ++    E  EE    ++  E  A+ 
Sbjct: 250 KQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309

Query: 391 R---SSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSS 447
                  +S  S +   +L      +P P+ S+ + + +D+ + +  + R S   D    
Sbjct: 310 DVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEM 369

Query: 448 SNIKNR 453
            ++  R
Sbjct: 370 QDMMTR 375



 Score = 36.6 bits (83), Expect = 0.071
 Identities = 15/46 (32%), Positives = 29/46 (63%)

Query: 194 EDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239
           ED+  E+ +++++ED  +++E EE E E+E   + E +   + EEE
Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305



 Score = 36.2 bits (82), Expect = 0.092
 Identities = 23/118 (19%), Positives = 55/118 (46%), Gaps = 9/118 (7%)

Query: 167 DEMTATRALINMSSLPAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSS 226
           +E +  + +++      +++    +  ED+  E+ +++++E+  +++E EE E E+E   
Sbjct: 246 EESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305

Query: 227 DVELDTLSQ-------VEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRS 277
           +   D + Q        ++   LR    P+ K      + +   + DDK E   +R+S
Sbjct: 306 EAAPDVIFQEDTSHTSAQKAPELRGPESPSPK--PEYSVIVEVRSDDDKDEDTHSRKS 361



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 17/48 (35%), Positives = 27/48 (56%)

Query: 192 ASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239
           ASE+ S +K     +E+  +++E EE E EDE   + E +   + EEE
Sbjct: 244 ASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEE 291



 Score = 33.1 bits (74), Expect = 0.78
 Identities = 14/51 (27%), Positives = 29/51 (56%)

Query: 189 SRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239
           S ++S+ K     +++ +E+  +++E EE E E+E   + E +   + EEE
Sbjct: 245 SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEE 295



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 12/63 (19%), Positives = 34/63 (53%)

Query: 177 NMSSLPAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQV 236
           ++    +++  + +     +  ++ +++++E+  +D+E EE E E+E   + E +   + 
Sbjct: 239 SLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEE 298

Query: 237 EEE 239
           EEE
Sbjct: 299 EEE 301


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 54/246 (21%), Positives = 105/246 (42%), Gaps = 21/246 (8%)

Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVED--ENSSDVELDTLSQVEEESL 241
           ++K  +R   +++  E+RK+ ++E      E E  +  +     S  E D L Q+E +  
Sbjct: 106 KEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRE 165

Query: 242 LRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKR 301
               +R   K  +  +   R A ++ +KE  A R    + +    +Y     + ++ W R
Sbjct: 166 RERKMREQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDK--VKASHWSR 222

Query: 302 --------RYH----SRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEE 349
                   R+      + ++ + +++R L+ D   ++  + + S   +   E     EEE
Sbjct: 223 SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 282

Query: 350 EEEEEEEEEEDQDMDADDRVVVEYHEELPAL----KQPRERSASRRSSASSSDSDEMDYD 405
           EEEEEEEEEE    +  +    E  EE        ++  E+SA   S    S+ +E + +
Sbjct: 283 EEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 342

Query: 406 LELKMI 411
             L ++
Sbjct: 343 NHLLVV 348



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 66/266 (24%), Positives = 114/266 (42%), Gaps = 47/266 (17%)

Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVED-------ENSSDVELDTLSQ- 235
           Q+K R ++  E+K+  KR K+  +  S  D  EEGE+ D        NS     D++   
Sbjct: 18  QEKKRRKE-QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76

Query: 236 -VEEESLLRNDLRPANKLAKGNRLFMRFATKDDK-KELGAARRSQYYMKY-GNPNYGGMK 292
             E++SL    ++P  ++++  ++  R   KD+K KE   AR  +   ++     +   +
Sbjct: 77  GEEDDSLA---IKPPQQMSRKEKVHHR---KDEKRKEKKHARVKEKEREHERRKRHREEQ 130

Query: 293 GILSNSWKR-------RYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEE 345
                 W+R       R HSRR +RD +++         L   + R   +    +E  E+
Sbjct: 131 DKARREWERQKRREMAREHSRR-ERDRLEQ---------LERKRERERKMREQQKEQREQ 180

Query: 346 EEEEE--EEEEEEEEEDQDMDADDRVVVE-YHEELPAL-------KQPRER--SASRRSS 393
           +E E   EE  +E E  +++ A  R + E Y +++ A        + PRER      R  
Sbjct: 181 KERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKP 240

Query: 394 ASSSDSDEMDYDLELKMISTPSPKKS 419
                 +E D   +L+ IS    K S
Sbjct: 241 VKEEKMEERDLLSDLQDISDSERKTS 266


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 54/246 (21%), Positives = 105/246 (42%), Gaps = 21/246 (8%)

Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVED--ENSSDVELDTLSQVEEESL 241
           ++K  +R   +++  E+RK+ ++E      E E  +  +     S  E D L Q+E +  
Sbjct: 72  KEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRE 131

Query: 242 LRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKR 301
               +R   K  +  +   R A ++ +KE  A R    + +    +Y     + ++ W R
Sbjct: 132 RERKMREQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDK--VKASHWSR 188

Query: 302 --------RYH----SRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEE 349
                   R+      + ++ + +++R L+ D   ++  + + S   +   E     EEE
Sbjct: 189 SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 248

Query: 350 EEEEEEEEEEDQDMDADDRVVVEYHEELPAL----KQPRERSASRRSSASSSDSDEMDYD 405
           EEEEEEEEEE    +  +    E  EE        ++  E+SA   S    S+ +E + +
Sbjct: 249 EEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 308

Query: 406 LELKMI 411
             L ++
Sbjct: 309 NHLLVV 314


>gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo
           sapiens]
          Length = 652

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 59/246 (23%), Positives = 95/246 (38%), Gaps = 37/246 (15%)

Query: 344 EEEEEEEEEEEEEEEEDQDMDADDRVVV-EYHEELPALKQPRERSASRRSSASSSDSDEM 402
           + E + E EEEE+E+ED+D D D+R ++ E+ +EL  +  P +R   R  +    D D +
Sbjct: 406 DPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGL 465

Query: 403 DYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEK 462
             + E          +   M      +   +K +      + V     K  +  K PP  
Sbjct: 466 KKESE----------RDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPS- 514

Query: 463 FADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGK-RPHSPEKAFSSNPVVRREPSSDVHS 521
                           P+P     +  +R R+ K R   P +  +   + R  P      
Sbjct: 515 ----------------PQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIE 558

Query: 522 RLGVPRQDSKGLYADTR-EKKSGNLW---TRLGSAPKTKE--KNTKKV--DHRAPGAEED 573
            L     + +GL A  + E K    W   T  G+   T E  +N K++  +   PGAEE 
Sbjct: 559 GLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEEA 618

Query: 574 DSELQR 579
             E QR
Sbjct: 619 QKERQR 624


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 51/240 (21%), Positives = 101/240 (42%), Gaps = 19/240 (7%)

Query: 188 RSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLRNDLR 247
           R ++   +    KR +++Q+ +  + E ++        S  E D L Q+E +      +R
Sbjct: 89  RVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR 148

Query: 248 PANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKR------ 301
              K  +  +   R A ++ +KE  A R    + +    +Y     + ++ W R      
Sbjct: 149 EQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDK--VKASHWSRSPPRPP 205

Query: 302 --RYH----SRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEE 355
             R+      + ++ + +++R L+ D   ++  + + S   +   E     EEEEEEEEE
Sbjct: 206 RERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE 265

Query: 356 EEEEDQDMDADDRVVVEYHEELPAL----KQPRERSASRRSSASSSDSDEMDYDLELKMI 411
           EEEE    +  +    E  EE        ++  E+SA   S    S+ +E + +  L ++
Sbjct: 266 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 325



 Score = 34.3 bits (77), Expect = 0.35
 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 6/62 (9%)

Query: 185 DKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEG------EVEDENSSDVELDTLSQVEE 238
           D  R   ++E  SAE     ++E+  +++E EEG      E E+E   + E +T S  EE
Sbjct: 237 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 296

Query: 239 ES 240
            S
Sbjct: 297 AS 298


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 51/240 (21%), Positives = 101/240 (42%), Gaps = 19/240 (7%)

Query: 188 RSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLRNDLR 247
           R ++   +    KR +++Q+ +  + E ++        S  E D L Q+E +      +R
Sbjct: 123 RVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR 182

Query: 248 PANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKR------ 301
              K  +  +   R A ++ +KE  A R    + +    +Y     + ++ W R      
Sbjct: 183 EQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDK--VKASHWSRSPPRPP 239

Query: 302 --RYH----SRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEE 355
             R+      + ++ + +++R L+ D   ++  + + S   +   E     EEEEEEEEE
Sbjct: 240 RERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE 299

Query: 356 EEEEDQDMDADDRVVVEYHEELPAL----KQPRERSASRRSSASSSDSDEMDYDLELKMI 411
           EEEE    +  +    E  EE        ++  E+SA   S    S+ +E + +  L ++
Sbjct: 300 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 359



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 69/304 (22%), Positives = 124/304 (40%), Gaps = 50/304 (16%)

Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVED-------ENSSDVELDTLSQ- 235
           Q+K R ++  E+K+  KR K+  +  S  D  EEGE+ D        NS     D++   
Sbjct: 18  QEKKRRKE-QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76

Query: 236 -VEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGI 294
             E++SL    ++P  ++++  ++  R   KD+K++     RS         +  G K  
Sbjct: 77  GEEDDSLA---IKPPQQMSRKEKVHHR---KDEKRKEKRRHRSH--------SAEGGKHA 122

Query: 295 LSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEE 354
                +R +  R+  R+   K     +          HS       E +E + E E +  
Sbjct: 123 RVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR 182

Query: 355 EEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMI--- 411
           E+++E ++         +   E  A ++ +ER A R  SA      E DY  ++K     
Sbjct: 183 EQQKEQRE---------QKERERRAEERRKEREARREVSAHHRTMRE-DYSDKVKASHWS 232

Query: 412 -STPSP-----------KKSMKMTMYADEVESQLKNIRNSMR-ADSVSSSNIKNRIGNKL 458
            S P P           K   +  M   ++ S L++I +S R   S  SS+ ++  G++ 
Sbjct: 233 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE 292

Query: 459 PPEK 462
             E+
Sbjct: 293 EEEE 296



 Score = 34.3 bits (77), Expect = 0.35
 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 6/62 (9%)

Query: 185 DKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEG------EVEDENSSDVELDTLSQVEE 238
           D  R   ++E  SAE     ++E+  +++E EEG      E E+E   + E +T S  EE
Sbjct: 271 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 330

Query: 239 ES 240
            S
Sbjct: 331 AS 332



 Score = 29.6 bits (65), Expect = 8.6
 Identities = 61/291 (20%), Positives = 112/291 (38%), Gaps = 23/291 (7%)

Query: 341 EPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSD 400
           + I +E++  +E+EE+ E  +  ++DDR       E   L+  R     R S     DS 
Sbjct: 14  DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSM 73

Query: 401 EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRN-SMRADSVSSSNIKNR----IG 455
           E   + +  +   P  + S K  ++  + E + +  R+ S  A+    + +K +      
Sbjct: 74  EDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHER 133

Query: 456 NKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHS---PEKAFSSNPVVR 512
            K   E+    R   + +++    R      +  + Q   KR       E+         
Sbjct: 134 RKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE 193

Query: 513 REPSSDVHSRLGVPRQDSKGLYADTRE----KKSGNLWTRLGSAPKTKEKNTKKVDHRAP 568
           RE  ++   +    R++    +   RE    K   + W+R  S P+   +  +  D R P
Sbjct: 194 RERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSR--SPPRPPRERFELGDGRKP 251

Query: 569 GAEEDDSELQRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAE 619
             EE   E  R   + +++   S +K S  ++        S ES SGSE E
Sbjct: 252 VKEEKMEE--RDLLSDLQDISDSERKTSSAES-------SSAESGSGSEEE 293


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 12/126 (9%)

Query: 338 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSA--------S 389
           V E+  EEEEEEEEEEEEEEEE+++ + D+R   E   +     +  +  +        S
Sbjct: 225 VDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGS 284

Query: 390 RRSSASSSDSDEMDYDLELKMISTP---SPKKSMKMTMYADEVESQLKNIRNSMRADSVS 446
            RS + +  SDE   + +     +P       S     YAD+  S+LK +    R   + 
Sbjct: 285 VRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYADQT-SKLKYVLQDARFFLIK 343

Query: 447 SSNIKN 452
           S+N +N
Sbjct: 344 SNNHEN 349



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 4/84 (4%)

Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDS 399
           EE +EE+ EE+EE EE+ EED+++D D     E  EE    ++  E            D 
Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEE----EEEEEEEEEEEYEQDERDQ 257

Query: 400 DEMDYDLELKMISTPSPKKSMKMT 423
            E   D + +  ++ S  +S+  T
Sbjct: 258 KEEGNDYDTRSEASDSGSESVSFT 281



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 8/98 (8%)

Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDS 399
           EE  EE+EE +E+ EEEEEE+++ + ++    E +E+    ++        RS AS S S
Sbjct: 216 EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGS 275

Query: 400 DEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIR 437
           + + +        T    +S   T  +DE + + K  R
Sbjct: 276 ESVSF--------TDGSVRSGSGTDGSDEKKKERKRAR 305



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 15/49 (30%), Positives = 25/49 (51%)

Query: 191 DASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239
           D  ED+  E+  ++ +E   D +E EE E E+E   + E +   Q E +
Sbjct: 208 DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERD 256



 Score = 29.6 bits (65), Expect = 8.6
 Identities = 16/69 (23%), Positives = 33/69 (47%), Gaps = 8/69 (11%)

Query: 179 SSLPAQDKIRSRDASEDKSA--------EKRKKDKQEDSSDDDEAEEGEVEDENSSDVEL 230
           SS  +++++ S +   D           +    + +E+  ++D  E+ EVE++   D E+
Sbjct: 166 SSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEV 225

Query: 231 DTLSQVEEE 239
           D   + EEE
Sbjct: 226 DEDGEEEEE 234


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 51/239 (21%), Positives = 100/239 (41%), Gaps = 19/239 (7%)

Query: 189 SRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLRNDLRP 248
           +R    +    KR +++Q+ +  + E ++        S  E D L Q+E +      +R 
Sbjct: 112 ARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMRE 171

Query: 249 ANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKR------- 301
             K  +  +   R A ++ +KE  A R    + +    +Y     + ++ W R       
Sbjct: 172 QQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDK--VKASHWSRSPPRPPR 228

Query: 302 -RYH----SRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEE 356
            R+      + ++ + +++R L+ D   ++  + + S   +   E     EEEEEEEEEE
Sbjct: 229 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 288

Query: 357 EEEDQDMDADDRVVVEYHEELPAL----KQPRERSASRRSSASSSDSDEMDYDLELKMI 411
           EEE    +  +    E  EE        ++  E+SA   S    S+ +E + +  L ++
Sbjct: 289 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 347



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 65/265 (24%), Positives = 111/265 (41%), Gaps = 46/265 (17%)

Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVED-------ENSSDVELDTLSQ- 235
           Q+K R ++  E+K+  KR K+  +  S  D  EEGE+ D        NS     D++   
Sbjct: 18  QEKKRRKE-QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76

Query: 236 -VEEESLLRNDLRPANKLAKGNRLFMRFATKDDK-KELGAARRSQYYMKYGNPNYGGMKG 293
             E++SL    ++P  ++++  ++  R   KD+K KE     R +         +   + 
Sbjct: 77  GEEDDSLA---IKPPQQMSRKEKVHHR---KDEKRKEKWKHARVKEREHERRKRHREEQD 130

Query: 294 ILSNSWKR-------RYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEE 346
                W+R       R HSRR +RD +++         L   + R   +    +E  E++
Sbjct: 131 KARREWERQKRREMAREHSRR-ERDRLEQ---------LERKRERERKMREQQKEQREQK 180

Query: 347 EEEE--EEEEEEEEEDQDMDADDRVVVE-YHEELPAL-------KQPRER--SASRRSSA 394
           E E   EE  +E E  +++ A  R + E Y +++ A        + PRER      R   
Sbjct: 181 ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 240

Query: 395 SSSDSDEMDYDLELKMISTPSPKKS 419
                +E D   +L+ IS    K S
Sbjct: 241 KEEKMEERDLLSDLQDISDSERKTS 265



 Score = 34.3 bits (77), Expect = 0.35
 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 6/62 (9%)

Query: 185 DKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEG------EVEDENSSDVELDTLSQVEE 238
           D  R   ++E  SAE     ++E+  +++E EEG      E E+E   + E +T S  EE
Sbjct: 259 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 318

Query: 239 ES 240
            S
Sbjct: 319 AS 320


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 51/239 (21%), Positives = 100/239 (41%), Gaps = 19/239 (7%)

Query: 189 SRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLRNDLRP 248
           +R    +    KR +++Q+ +  + E ++        S  E D L Q+E +      +R 
Sbjct: 122 ARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMRE 181

Query: 249 ANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKR------- 301
             K  +  +   R A ++ +KE  A R    + +    +Y     + ++ W R       
Sbjct: 182 QQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDK--VKASHWSRSPPRPPR 238

Query: 302 -RYH----SRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEE 356
            R+      + ++ + +++R L+ D   ++  + + S   +   E     EEEEEEEEEE
Sbjct: 239 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 298

Query: 357 EEEDQDMDADDRVVVEYHEELPAL----KQPRERSASRRSSASSSDSDEMDYDLELKMI 411
           EEE    +  +    E  EE        ++  E+SA   S    S+ +E + +  L ++
Sbjct: 299 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 357



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 67/304 (22%), Positives = 125/304 (41%), Gaps = 52/304 (17%)

Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVED-------ENSSDVELDTLSQ- 235
           Q+K R ++  E+K+  KR K+  +  S  D  EEGE+ D        NS     D++   
Sbjct: 18  QEKKRRKE-QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76

Query: 236 -VEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGI 294
             E++SL    ++P  ++++  ++  R   KD+K++           K  + ++    G 
Sbjct: 77  GEEDDSLA---IKPPQQMSRKEKVHHR---KDEKRK----------EKCRHHSHSAEGGK 120

Query: 295 LSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEE 354
            +   +R +  R+  R+   K     +          HS       E +E + E E +  
Sbjct: 121 HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR 180

Query: 355 EEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMI--- 411
           E+++E ++         +   E  A ++ +ER A R  SA      E DY  ++K     
Sbjct: 181 EQQKEQRE---------QKERERRAEERRKEREARREVSAHHRTMRE-DYSDKVKASHWS 230

Query: 412 -STPSP-----------KKSMKMTMYADEVESQLKNIRNSMR-ADSVSSSNIKNRIGNKL 458
            S P P           K   +  M   ++ S L++I +S R   S  SS+ ++  G++ 
Sbjct: 231 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE 290

Query: 459 PPEK 462
             E+
Sbjct: 291 EEEE 294



 Score = 34.3 bits (77), Expect = 0.35
 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 6/62 (9%)

Query: 185 DKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEG------EVEDENSSDVELDTLSQVEE 238
           D  R   ++E  SAE     ++E+  +++E EEG      E E+E   + E +T S  EE
Sbjct: 269 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 328

Query: 239 ES 240
            S
Sbjct: 329 AS 330



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 63/294 (21%), Positives = 115/294 (39%), Gaps = 31/294 (10%)

Query: 341 EPIEEEEEEEEEEEEEEEEDQDMDADD----RVVVEYHEELPALKQPRERSASRRSSASS 396
           + I +E++  +E+EE+ E  +  ++DD    R  +E  E      +   R++  R   S 
Sbjct: 14  DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSM 73

Query: 397 SDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIR-NSMRADSVSSSNIKNRIG 455
            D  E D  L +K    P  + S K  ++  + E + +  R +S  A+    + +K R  
Sbjct: 74  EDRGEEDDSLAIK----PPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKEREH 129

Query: 456 NKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREP 515
            +    +    +   + +RQ  R      S +   R    +R    E+        +RE 
Sbjct: 130 ERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQRE- 188

Query: 516 SSDVHSRLGVPRQDSKG----------LYADTREKKSGNLWTRLGSAPKTKEKNTKKVDH 565
             +   R    R++ +           +  D  +K   + W+R  S P+   +  +  D 
Sbjct: 189 QKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSR--SPPRPPRERFELGDG 246

Query: 566 RAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAE 619
           R P  EE   E  R   + +++   S +K S  ++        S ES SGSE E
Sbjct: 247 RKPVKEEKMEE--RDLLSDLQDISDSERKTSSAES-------SSAESGSGSEEE 291


>gi|33391150 nucleoplasmin 2 [Homo sapiens]
          Length = 214

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 5/83 (6%)

Query: 344 EEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMD 403
           EEEEEE EEEEEEEE+D+D DAD  +     EE   +KQ +     +++S +     E +
Sbjct: 130 EEEEEEGEEEEEEEEDDEDEDADISL-----EEQSPVKQVKRLVPQKQASVAKKKKLEKE 184

Query: 404 YDLELKMISTPSPKKSMKMTMYA 426
            +     +   SP K  K T  A
Sbjct: 185 EEEIRASVRDKSPVKKAKATARA 207


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 94/482 (19%), Positives = 196/482 (40%), Gaps = 88/482 (18%)

Query: 172  TRALINMSSLPA--QDKIRSRDASEDKSAEKRKKDKQ-----EDSSDDDEAEEGEVEDEN 224
            ++ ++   SLPA  Q   R R   +++  ++R  DK      E++S   + + GE  +++
Sbjct: 847  SKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKS 906

Query: 225  SSDVELDTLSQVEEESLLRNDLRPAN-------------------------------KLA 253
             +  E  T S   EE L+ ++ +P+                                +L 
Sbjct: 907  EATQEQYTES---EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLT 963

Query: 254  KGNRLFMRFATKDDKKEL-GAARRSQYYMKYGNPNYGGMKGILSNSWKRR----YHSRRI 308
            +G+    R  ++ D+  L G +  S+   +  +P       +   + KR+    +  RR+
Sbjct: 964  EGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRV 1023

Query: 309  QRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEE-----EEEEEEEEEDQDM 363
            ++      +++ + +  T+          V +EP E+ + E      E   E +EE+++ 
Sbjct: 1024 RKRKHHNSSVVTETISETT---------EVLDEPFEDSDSERPMPRLEPTFEIDEEEEEE 1074

Query: 364  DADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPS--PKKSMK 421
            D ++    EY   L +    R +S+S+R S    + +E D   +  ++   S   K+ +K
Sbjct: 1075 DENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVK 1134

Query: 422  MTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRP 481
             +    +  + LK  +   +  S    + K R G K P  K +  R ++    Q     P
Sbjct: 1135 NSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRK-PGFKLS--REIMPVSTQACVIEP 1191

Query: 482  PVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKK 541
             VS  K+      G++P   E   S   V   EP  D+   L   R++ + + A+  E +
Sbjct: 1192 IVSIPKA------GRKPKIQE---SEETV---EPKEDM--PLPEERKEEEEMQAEAEEAE 1237

Query: 542  SGN----LWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSR 597
             G       + + +A      N+ + + + P  EE++ + +     + +E+ QS +++  
Sbjct: 1238 EGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPR-----VSEEQRQSEEEQQE 1292

Query: 598  LD 599
            L+
Sbjct: 1293 LE 1294



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 65/282 (23%), Positives = 97/282 (34%), Gaps = 60/282 (21%)

Query: 338  VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 397
            +PEE  EEEE + E EE EE E++D  +          E+PA            S A SS
Sbjct: 1219 LPEERKEEEEMQAEAEEAEEGEEEDAASS---------EVPAA-----------SPADSS 1258

Query: 398  DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNK 457
            +S E +         T  P+          E E +   +    R        ++      
Sbjct: 1259 NSPETE---------TKEPEV---------EEEEEKPRVSEEQRQSEEEQQELEEP---- 1296

Query: 458  LPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSS 517
              PE+  D      +   H          +S  ++ L ++P   +        V+ EP  
Sbjct: 1297 -EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRED--------VKEEP-- 1345

Query: 518  DVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSEL 577
                  GV           +REK      T L S  +    +T  V  +  G+E+D  E 
Sbjct: 1346 ------GVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEED 1399

Query: 578  QRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAE 619
                  LI+ KE+     S LD L ++Q   S      SE E
Sbjct: 1400 SHTKEELIELKEEEEIPHSELD-LETVQAVQSLTQEESSEHE 1440



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 65/307 (21%), Positives = 122/307 (39%), Gaps = 49/307 (15%)

Query: 184  QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDV------------ELD 231
            Q+   + +  ED    + +K+++E  ++ +EAEEGE ED  SS+V            E +
Sbjct: 1205 QESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETE 1264

Query: 232  TLS-QVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGG 290
            T   +VEEE       R + +  +           + ++E  AA  +     +   +   
Sbjct: 1265 TKEPEVEEEE---EKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDD 1321

Query: 291  MKGILSNSWKRRYHSRRIQRDVI---------------KKRALIGD--DVGLTSYKHRHS 333
              G L ++ K+    +  + DV                K R  I D  +  L S + + S
Sbjct: 1322 --GHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPS 1379

Query: 334  GLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSS 393
               +V  E +   E++ EE+   +EE  ++  ++ +    H EL  L+  +   +  +  
Sbjct: 1380 HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIP---HSELD-LETVQAVQSLTQEE 1435

Query: 394  ASSSDSDEMDYDLELKMIST--------PSPKKSMKMTMYADEVESQLKNIRN--SMRAD 443
            +S  +    D +  L    T          P+ SM    +A E  S + ++++  S    
Sbjct: 1436 SSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVR 1495

Query: 444  SVSSSNI 450
            SVSS N+
Sbjct: 1496 SVSSPNV 1502


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 94/482 (19%), Positives = 196/482 (40%), Gaps = 88/482 (18%)

Query: 172  TRALINMSSLPA--QDKIRSRDASEDKSAEKRKKDKQ-----EDSSDDDEAEEGEVEDEN 224
            ++ ++   SLPA  Q   R R   +++  ++R  DK      E++S   + + GE  +++
Sbjct: 847  SKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKS 906

Query: 225  SSDVELDTLSQVEEESLLRNDLRPAN-------------------------------KLA 253
             +  E  T S   EE L+ ++ +P+                                +L 
Sbjct: 907  EATQEQYTES---EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLT 963

Query: 254  KGNRLFMRFATKDDKKEL-GAARRSQYYMKYGNPNYGGMKGILSNSWKRR----YHSRRI 308
            +G+    R  ++ D+  L G +  S+   +  +P       +   + KR+    +  RR+
Sbjct: 964  EGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRV 1023

Query: 309  QRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEE-----EEEEEEEEEDQDM 363
            ++      +++ + +  T+          V +EP E+ + E      E   E +EE+++ 
Sbjct: 1024 RKRKHHNSSVVTETISETT---------EVLDEPFEDSDSERPMPRLEPTFEIDEEEEEE 1074

Query: 364  DADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPS--PKKSMK 421
            D ++    EY   L +    R +S+S+R S    + +E D   +  ++   S   K+ +K
Sbjct: 1075 DENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVK 1134

Query: 422  MTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRP 481
             +    +  + LK  +   +  S    + K R G K P  K +  R ++    Q     P
Sbjct: 1135 NSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRK-PGFKLS--REIMPVSTQACVIEP 1191

Query: 482  PVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKK 541
             VS  K+      G++P   E   S   V   EP  D+   L   R++ + + A+  E +
Sbjct: 1192 IVSIPKA------GRKPKIQE---SEETV---EPKEDM--PLPEERKEEEEMQAEAEEAE 1237

Query: 542  SGN----LWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSR 597
             G       + + +A      N+ + + + P  EE++ + +     + +E+ QS +++  
Sbjct: 1238 EGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPR-----VSEEQRQSEEEQQE 1292

Query: 598  LD 599
            L+
Sbjct: 1293 LE 1294



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 65/282 (23%), Positives = 97/282 (34%), Gaps = 60/282 (21%)

Query: 338  VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 397
            +PEE  EEEE + E EE EE E++D  +          E+PA            S A SS
Sbjct: 1219 LPEERKEEEEMQAEAEEAEEGEEEDAASS---------EVPAA-----------SPADSS 1258

Query: 398  DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNK 457
            +S E +         T  P+          E E +   +    R        ++      
Sbjct: 1259 NSPETE---------TKEPEV---------EEEEEKPRVSEEQRQSEEEQQELEEP---- 1296

Query: 458  LPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSS 517
              PE+  D      +   H          +S  ++ L ++P   +        V+ EP  
Sbjct: 1297 -EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRED--------VKEEP-- 1345

Query: 518  DVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSEL 577
                  GV           +REK      T L S  +    +T  V  +  G+E+D  E 
Sbjct: 1346 ------GVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEED 1399

Query: 578  QRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAE 619
                  LI+ KE+     S LD L ++Q   S      SE E
Sbjct: 1400 SHTKEELIELKEEEEIPHSELD-LETVQAVQSLTQEESSEHE 1440



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 65/307 (21%), Positives = 122/307 (39%), Gaps = 49/307 (15%)

Query: 184  QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDV------------ELD 231
            Q+   + +  ED    + +K+++E  ++ +EAEEGE ED  SS+V            E +
Sbjct: 1205 QESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETE 1264

Query: 232  TLS-QVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGG 290
            T   +VEEE       R + +  +           + ++E  AA  +     +   +   
Sbjct: 1265 TKEPEVEEEE---EKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDD 1321

Query: 291  MKGILSNSWKRRYHSRRIQRDVI---------------KKRALIGD--DVGLTSYKHRHS 333
              G L ++ K+    +  + DV                K R  I D  +  L S + + S
Sbjct: 1322 --GHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPS 1379

Query: 334  GLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSS 393
               +V  E +   E++ EE+   +EE  ++  ++ +    H EL  L+  +   +  +  
Sbjct: 1380 HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIP---HSELD-LETVQAVQSLTQEE 1435

Query: 394  ASSSDSDEMDYDLELKMIST--------PSPKKSMKMTMYADEVESQLKNIRN--SMRAD 443
            +S  +    D +  L    T          P+ SM    +A E  S + ++++  S    
Sbjct: 1436 SSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVR 1495

Query: 444  SVSSSNI 450
            SVSS N+
Sbjct: 1496 SVSSPNV 1502


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 94/482 (19%), Positives = 196/482 (40%), Gaps = 88/482 (18%)

Query: 172  TRALINMSSLPA--QDKIRSRDASEDKSAEKRKKDKQ-----EDSSDDDEAEEGEVEDEN 224
            ++ ++   SLPA  Q   R R   +++  ++R  DK      E++S   + + GE  +++
Sbjct: 847  SKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKS 906

Query: 225  SSDVELDTLSQVEEESLLRNDLRPAN-------------------------------KLA 253
             +  E  T S   EE L+ ++ +P+                                +L 
Sbjct: 907  EATQEQYTES---EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLT 963

Query: 254  KGNRLFMRFATKDDKKEL-GAARRSQYYMKYGNPNYGGMKGILSNSWKRR----YHSRRI 308
            +G+    R  ++ D+  L G +  S+   +  +P       +   + KR+    +  RR+
Sbjct: 964  EGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRV 1023

Query: 309  QRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEE-----EEEEEEEEEDQDM 363
            ++      +++ + +  T+          V +EP E+ + E      E   E +EE+++ 
Sbjct: 1024 RKRKHHNSSVVTETISETT---------EVLDEPFEDSDSERPMPRLEPTFEIDEEEEEE 1074

Query: 364  DADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPS--PKKSMK 421
            D ++    EY   L +    R +S+S+R S    + +E D   +  ++   S   K+ +K
Sbjct: 1075 DENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVK 1134

Query: 422  MTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRP 481
             +    +  + LK  +   +  S    + K R G K P  K +  R ++    Q     P
Sbjct: 1135 NSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRK-PGFKLS--REIMPVSTQACVIEP 1191

Query: 482  PVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKK 541
             VS  K+      G++P   E   S   V   EP  D+   L   R++ + + A+  E +
Sbjct: 1192 IVSIPKA------GRKPKIQE---SEETV---EPKEDM--PLPEERKEEEEMQAEAEEAE 1237

Query: 542  SGN----LWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSR 597
             G       + + +A      N+ + + + P  EE++ + +     + +E+ QS +++  
Sbjct: 1238 EGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPR-----VSEEQRQSEEEQQE 1292

Query: 598  LD 599
            L+
Sbjct: 1293 LE 1294



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 65/282 (23%), Positives = 97/282 (34%), Gaps = 60/282 (21%)

Query: 338  VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 397
            +PEE  EEEE + E EE EE E++D  +          E+PA            S A SS
Sbjct: 1219 LPEERKEEEEMQAEAEEAEEGEEEDAASS---------EVPAA-----------SPADSS 1258

Query: 398  DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNK 457
            +S E +         T  P+          E E +   +    R        ++      
Sbjct: 1259 NSPETE---------TKEPEV---------EEEEEKPRVSEEQRQSEEEQQELEEP---- 1296

Query: 458  LPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSS 517
              PE+  D      +   H          +S  ++ L ++P   +        V+ EP  
Sbjct: 1297 -EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRED--------VKEEP-- 1345

Query: 518  DVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSEL 577
                  GV           +REK      T L S  +    +T  V  +  G+E+D  E 
Sbjct: 1346 ------GVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEED 1399

Query: 578  QRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAE 619
                  LI+ KE+     S LD L ++Q   S      SE E
Sbjct: 1400 SHTKEELIELKEEEEIPHSELD-LETVQAVQSLTQEESSEHE 1440



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 65/307 (21%), Positives = 122/307 (39%), Gaps = 49/307 (15%)

Query: 184  QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDV------------ELD 231
            Q+   + +  ED    + +K+++E  ++ +EAEEGE ED  SS+V            E +
Sbjct: 1205 QESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETE 1264

Query: 232  TLS-QVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGG 290
            T   +VEEE       R + +  +           + ++E  AA  +     +   +   
Sbjct: 1265 TKEPEVEEEE---EKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDD 1321

Query: 291  MKGILSNSWKRRYHSRRIQRDVI---------------KKRALIGD--DVGLTSYKHRHS 333
              G L ++ K+    +  + DV                K R  I D  +  L S + + S
Sbjct: 1322 --GHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPS 1379

Query: 334  GLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSS 393
               +V  E +   E++ EE+   +EE  ++  ++ +    H EL  L+  +   +  +  
Sbjct: 1380 HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIP---HSELD-LETVQAVQSLTQEE 1435

Query: 394  ASSSDSDEMDYDLELKMIST--------PSPKKSMKMTMYADEVESQLKNIRN--SMRAD 443
            +S  +    D +  L    T          P+ SM    +A E  S + ++++  S    
Sbjct: 1436 SSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVR 1495

Query: 444  SVSSSNI 450
            SVSS N+
Sbjct: 1496 SVSSPNV 1502


>gi|122937227 U2-associated SR140 protein [Homo sapiens]
          Length = 1029

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 55/239 (23%), Positives = 97/239 (40%), Gaps = 19/239 (7%)

Query: 344  EEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMD 403
            EE EEEE + +EEE ED++ D       E+H     +K+    S   + S  S +     
Sbjct: 786  EESEEEENQNQEEESEDEE-DTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKL 844

Query: 404  YDLELKMI-------STPSPKK-----SMKMTMYADEV--ESQLKNIRNSMRADSVSSSN 449
             ++ELK++       S   PKK       ++  Y D++    + K +      D      
Sbjct: 845  REIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEK 904

Query: 450  IKNRIGNKLPPEKFADVRHLLDEKRQHS-RPRPPVSSTKSDIRQRLGKRPHSPEKAFSSN 508
            +++R  +K   ++    R   + KR+HS  P P  SS+   ++    K   S E++  S+
Sbjct: 905  LESRSKDKKEKDECTPTRK--ERKRRHSTSPSPSRSSSGRRVKSPSPKSERS-ERSERSH 961

Query: 509  PVVRREPSSDVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRA 567
                R  SS   S   V ++  +        K+S    +R       K ++  +  HR+
Sbjct: 962  KESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRS 1020



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 52/263 (19%), Positives = 84/263 (31%), Gaps = 57/263 (21%)

Query: 341  EPIEEEEEEEEEEEEEEEED----------------------------QDMDADDRV--- 369
            E  EEEE + +EEE E+EED                             +M  + R    
Sbjct: 786  EESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLR 845

Query: 370  -----VVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTM 424
                 V+++ +EL + K+P++   S +          +  + E ++       K  K   
Sbjct: 846  EIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDK--- 902

Query: 425  YADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVS 484
              +++ES+ K+ +             K R      P + +  R +     +  R      
Sbjct: 903  --EKLESRSKDKKEKDECTPTRKER-KRRHSTSPSPSRSSSGRRVKSPSPKSERSERSER 959

Query: 485  STKSDIRQRLGKR--PHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKKS 542
            S K   R R   +  P    K    +P   R P     SR   P             KKS
Sbjct: 960  SHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSP-------------KKS 1006

Query: 543  GNLWTRLGSAPKTKEKNTKKVDH 565
            G        +P    K +KK  H
Sbjct: 1007 GKKSRSQSRSPHRSHKKSKKNKH 1029


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 42/161 (26%), Positives = 70/161 (43%), Gaps = 20/161 (12%)

Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRS------- 392
           E+  ++E+E+E+++E+E E+D+  + D++   +     P    PR  +ASRRS       
Sbjct: 442 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP----PRSYNASRRSRSSSRER 497

Query: 393 ----SASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSS 448
               S SSS S      ++ K   +PSP+   K     ++    +   R   R+ S+  S
Sbjct: 498 RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 557

Query: 449 NIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSD 489
           +  +R G     EK       L EK  +  P   VS    D
Sbjct: 558 S-NDRDGK----EKLEKNSTSLKEKEHNKEPDSSVSKEVDD 593



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 55/244 (22%), Positives = 87/244 (35%), Gaps = 37/244 (15%)

Query: 338 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 397
           V E+  E+E E E+E E+E+E  ++ D D              ++ RE+   +       
Sbjct: 390 VKEKDREKEREREKEREKEKERGKNKDRDKE-----------REKDREKDKEKDRERERE 438

Query: 398 DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVS--SSNIKNRIG 455
              E D D E +       ++    +   DE   + K  R   R+ + S  S +      
Sbjct: 439 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERR 498

Query: 456 NKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREP 515
            +         R     KR+ SR   P S  K D ++R  +R H  E+         R+ 
Sbjct: 499 RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD-KKREKERDHISERRERERSTSMRKS 557

Query: 516 SSDVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDS 575
           S+D         +D K    +  EK S +L          KEK   K    +   E DD 
Sbjct: 558 SND---------RDGK----EKLEKNSTSL----------KEKEHNKEPDSSVSKEVDDK 594

Query: 576 ELQR 579
           +  R
Sbjct: 595 DAPR 598



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 43/194 (22%), Positives = 73/194 (37%), Gaps = 17/194 (8%)

Query: 426 ADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSS 485
           A E+E  +K +R    A S  S+ I+   G     +      H   + R  S+       
Sbjct: 272 AKELEEVMKRVRE---AQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKR 328

Query: 486 TKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKKSGNL 545
           ++S  R R   R  S +K    +    ++ S     R    R  S+    DTREK     
Sbjct: 329 SQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK----- 383

Query: 546 WTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLDNLPSLQ 605
              +    + KEK+ +K   R    +E + E +R      K++++ R+K    D     +
Sbjct: 384 ---IKEKERVKEKDREKERERE---KEREKEKERGKN---KDRDKEREKDREKDKEKDRE 434

Query: 606 IEVSRESSSGSEAE 619
            E  +E     + E
Sbjct: 435 REREKEHEKDRDKE 448



 Score = 33.9 bits (76), Expect = 0.46
 Identities = 34/184 (18%), Positives = 73/184 (39%), Gaps = 6/184 (3%)

Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLR 243
           +DK R +D  +DK  ++ ++ ++E   D D  +E E E +   + E D   +++E+    
Sbjct: 417 RDKEREKDREKDKEKDREREREKEHEKDRD--KEKEKEQDKEKEREKDRSKEIDEKRKKD 474

Query: 244 NDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRY 303
              R   +    +R     + +  ++   ++ RS    K         +     S  ++ 
Sbjct: 475 KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSK--TIKRKSSRSPSPRSRNKKD 532

Query: 304 HSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEE--PIEEEEEEEEEEEEEEEEDQ 361
             R  +RD I +R        +    +   G   + +    ++E+E  +E +    +E  
Sbjct: 533 KKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVD 592

Query: 362 DMDA 365
           D DA
Sbjct: 593 DKDA 596



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 50/236 (21%), Positives = 88/236 (37%), Gaps = 27/236 (11%)

Query: 186 KIRSRDASEDK--------------SAEKRKKDKQEDSSDDDEAEEGEVED---ENSSDV 228
           K RSR  S DK                + R+K+++ +   + E E G+ +D   E   D 
Sbjct: 366 KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR 425

Query: 229 ELDTLSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNY 288
           E D     E E    ++ +  +K  +  +   +   KD  KE+   R+     +    +Y
Sbjct: 426 EKDKEKDREREREKEHE-KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY 484

Query: 289 GGMKGILSNS-WKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEE 347
              +   S+S  +RR  SR   R     + +        S + R+       ++   E+E
Sbjct: 485 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK------KDKKREKE 538

Query: 348 EEEEEEEEEEEEDQDM--DADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDE 401
            +   E  E E    M   ++DR   E  E+     + +E +    SS S    D+
Sbjct: 539 RDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK 594


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 42/161 (26%), Positives = 70/161 (43%), Gaps = 20/161 (12%)

Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRS------- 392
           E+  ++E+E+E+++E+E E+D+  + D++   +     P    PR  +ASRRS       
Sbjct: 326 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP----PRSYNASRRSRSSSRER 381

Query: 393 ----SASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSS 448
               S SSS S      ++ K   +PSP+   K     ++    +   R   R+ S+  S
Sbjct: 382 RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 441

Query: 449 NIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSD 489
           +  +R G     EK       L EK  +  P   VS    D
Sbjct: 442 S-NDRDGK----EKLEKNSTSLKEKEHNKEPDSSVSKEVDD 477



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 55/244 (22%), Positives = 87/244 (35%), Gaps = 37/244 (15%)

Query: 338 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 397
           V E+  E+E E E+E E+E+E  ++ D D              ++ RE+   +       
Sbjct: 274 VKEKDREKEREREKEREKEKERGKNKDRDKE-----------REKDREKDKEKDRERERE 322

Query: 398 DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVS--SSNIKNRIG 455
              E D D E +       ++    +   DE   + K  R   R+ + S  S +      
Sbjct: 323 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERR 382

Query: 456 NKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREP 515
            +         R     KR+ SR   P S  K D ++R  +R H  E+         R+ 
Sbjct: 383 RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD-KKREKERDHISERRERERSTSMRKS 441

Query: 516 SSDVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDS 575
           S+D         +D K    +  EK S +L          KEK   K    +   E DD 
Sbjct: 442 SND---------RDGK----EKLEKNSTSL----------KEKEHNKEPDSSVSKEVDDK 478

Query: 576 ELQR 579
           +  R
Sbjct: 479 DAPR 482



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 43/194 (22%), Positives = 73/194 (37%), Gaps = 17/194 (8%)

Query: 426 ADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSS 485
           A E+E  +K +R    A S  S+ I+   G     +      H   + R  S+       
Sbjct: 156 AKELEEVMKRVRE---AQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKR 212

Query: 486 TKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKKSGNL 545
           ++S  R R   R  S +K    +    ++ S     R    R  S+    DTREK     
Sbjct: 213 SQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK----- 267

Query: 546 WTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLDNLPSLQ 605
              +    + KEK+ +K   R    +E + E +R      K++++ R+K    D     +
Sbjct: 268 ---IKEKERVKEKDREKERERE---KEREKEKERGKN---KDRDKEREKDREKDKEKDRE 318

Query: 606 IEVSRESSSGSEAE 619
            E  +E     + E
Sbjct: 319 REREKEHEKDRDKE 332



 Score = 33.9 bits (76), Expect = 0.46
 Identities = 34/184 (18%), Positives = 73/184 (39%), Gaps = 6/184 (3%)

Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLR 243
           +DK R +D  +DK  ++ ++ ++E   D D  +E E E +   + E D   +++E+    
Sbjct: 301 RDKEREKDREKDKEKDREREREKEHEKDRD--KEKEKEQDKEKEREKDRSKEIDEKRKKD 358

Query: 244 NDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRY 303
              R   +    +R     + +  ++   ++ RS    K         +     S  ++ 
Sbjct: 359 KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSK--TIKRKSSRSPSPRSRNKKD 416

Query: 304 HSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEE--PIEEEEEEEEEEEEEEEEDQ 361
             R  +RD I +R        +    +   G   + +    ++E+E  +E +    +E  
Sbjct: 417 KKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVD 476

Query: 362 DMDA 365
           D DA
Sbjct: 477 DKDA 480



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 50/236 (21%), Positives = 88/236 (37%), Gaps = 27/236 (11%)

Query: 186 KIRSRDASEDK--------------SAEKRKKDKQEDSSDDDEAEEGEVED---ENSSDV 228
           K RSR  S DK                + R+K+++ +   + E E G+ +D   E   D 
Sbjct: 250 KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR 309

Query: 229 ELDTLSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNY 288
           E D     E E    ++ +  +K  +  +   +   KD  KE+   R+     +    +Y
Sbjct: 310 EKDKEKDREREREKEHE-KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY 368

Query: 289 GGMKGILSNS-WKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEE 347
              +   S+S  +RR  SR   R     + +        S + R+       ++   E+E
Sbjct: 369 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK------KDKKREKE 422

Query: 348 EEEEEEEEEEEEDQDM--DADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDE 401
            +   E  E E    M   ++DR   E  E+     + +E +    SS S    D+
Sbjct: 423 RDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK 478


>gi|5803109 osteosarcoma amplified 9 isoform 1 precursor [Homo
           sapiens]
          Length = 667

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 59/252 (23%), Positives = 100/252 (39%), Gaps = 34/252 (13%)

Query: 344 EEEEEEEEEEEEEEEEDQDMDADDRVVV-EYHEELPALKQPRERSASRRSSASSSDSD-- 400
           + E + E EEEE+E+ED+D D D+R ++ E+ +EL  +  P +R   R    +  + +  
Sbjct: 406 DPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSEVKAGMERELE 465

Query: 401 ----EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGN 456
               E + +L+   +   S ++   M      +   +K +      + V     K  +  
Sbjct: 466 NIIQETEKELDPDGLKKES-ERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPK 524

Query: 457 KLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGK-RPHSPEKAFSSNPVVRREP 515
           K PP                  P+P     +  +R R+ K R   P +  +   + R  P
Sbjct: 525 KPPPS-----------------PQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENP 567

Query: 516 SSDVHSRLGVPRQDSKGLYADTR-EKKSGNLW---TRLGSAPKTKE--KNTKKV--DHRA 567
                  L     + +GL A  + E K    W   T  G+   T E  +N K++  +   
Sbjct: 568 QLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILV 627

Query: 568 PGAEEDDSELQR 579
           PGAEE   E QR
Sbjct: 628 PGAEEAQKERQR 639


>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
           sapiens]
          Length = 528

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 38/118 (32%), Positives = 55/118 (46%), Gaps = 23/118 (19%)

Query: 325 LTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPR 384
           LT  K     + + P E  EEEEEEEEEE EEEEE++D +          E  P L  P+
Sbjct: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSE----------EAPPPLSPPQ 346

Query: 385 ERSASRRSSASSSDSDEM-DYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMR 441
                    AS ++ D+M  YD + +     + +   K     +E E  LK++  S+R
Sbjct: 347 --------PASPAEEDKMPPYDEQTQAFIDAAQEARNKF----EEAERSLKDMEESIR 392


>gi|13376339 plasticity-related protein 2 [Homo sapiens]
          Length = 746

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 24/51 (47%), Positives = 34/51 (66%), Gaps = 2/51 (3%)

Query: 314 KKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMD 364
           K+++L G  +GL        G +  P EP+ EEEEEEE+EEEEEEE+++ D
Sbjct: 440 KQKSLEGRGLGLPD--DASPGHLRAPAEPMAEEEEEEEDEEEEEEEEEEED 488


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 41/129 (31%), Positives = 62/129 (48%), Gaps = 21/129 (16%)

Query: 338 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 397
           V E+  EEEEEEEEEEEEEEEE+++ + D+R   +  EE              RS AS S
Sbjct: 225 VDEDGEEEEEEEEEEEEEEEEEEEEYEQDER---DQKEE--------GNDYDTRSEASDS 273

Query: 398 DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIR--NSMRADSVSSSNIKNRIG 455
            S+ + +        T    +S   T  +DE + + K  R  + +  D   SS  ++  G
Sbjct: 274 GSESVSF--------TDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAG 325

Query: 456 NKLPPEKFA 464
           ++   EK +
Sbjct: 326 SEKKHEKLS 334



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 4/84 (4%)

Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDS 399
           EE +EE+ EE+EE EE+ EED+++D D     E  EE    ++  E            D 
Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEE----EEEEEEEEEEEYEQDERDQ 257

Query: 400 DEMDYDLELKMISTPSPKKSMKMT 423
            E   D + +  ++ S  +S+  T
Sbjct: 258 KEEGNDYDTRSEASDSGSESVSFT 281



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 15/49 (30%), Positives = 25/49 (51%)

Query: 191 DASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239
           D  ED+  E+  ++ +E   D +E EE E E+E   + E +   Q E +
Sbjct: 208 DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERD 256



 Score = 29.6 bits (65), Expect = 8.6
 Identities = 16/69 (23%), Positives = 33/69 (47%), Gaps = 8/69 (11%)

Query: 179 SSLPAQDKIRSRDASEDKSA--------EKRKKDKQEDSSDDDEAEEGEVEDENSSDVEL 230
           SS  +++++ S +   D           +    + +E+  ++D  E+ EVE++   D E+
Sbjct: 166 SSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEV 225

Query: 231 DTLSQVEEE 239
           D   + EEE
Sbjct: 226 DEDGEEEEE 234


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 55/199 (27%), Positives = 83/199 (41%), Gaps = 14/199 (7%)

Query: 288 YGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEE 347
           Y   K  LS+  +R     R++R       L    V L   + + +G     EE  +EEE
Sbjct: 685 YQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEE 744

Query: 348 EEE----EEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMD 403
           EEE    EEEEEEEEE+++ + ++         L  +  PR  S+S  S  S+  S E  
Sbjct: 745 EEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQEG- 803

Query: 404 YDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNI-KNRIGNKLPPEK 462
                  +     K+S      AD     L+    S     VS  ++ K+ +  +L P+ 
Sbjct: 804 ---APSTLLADDQKESRGRASMAD---GDLEPEEGSKTLVLVSPGDMKKSPVTAELAPD- 856

Query: 463 FADVRHLLDEKRQHSRPRP 481
             D+  L     QH RP+P
Sbjct: 857 -PDLGTLAALTPQHERPQP 874



 Score = 33.1 bits (74), Expect = 0.78
 Identities = 11/48 (22%), Positives = 28/48 (58%)

Query: 182 PAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVE 229
           P Q +   ++  E++  ++ ++++ E+  +++E EE E E+E   + E
Sbjct: 724 PVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 13/38 (34%), Positives = 24/38 (63%)

Query: 202 KKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239
           K++++E+  D++E EE E E+E   + E +   + EEE
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEE 769



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 12/44 (27%), Positives = 25/44 (56%)

Query: 183 AQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSS 226
           A  K    +  ED+  E+  ++++E+  +++E EE E E+E  +
Sbjct: 729 ANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEA 772



 Score = 29.6 bits (65), Expect = 8.6
 Identities = 11/41 (26%), Positives = 26/41 (63%)

Query: 200 KRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEES 240
           K +++++E+  +++E +E E E+E   + E +   + EEE+
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEA 772


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 55/255 (21%), Positives = 106/255 (41%), Gaps = 30/255 (11%)

Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDE---------AEEGEVEDENSSDVEL--DT 232
           ++K  +R   +++  E+RK+ ++E      E         A E    +  +  V L  D 
Sbjct: 106 KEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDR 165

Query: 233 LSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMK 292
           L Q+E +      +R   K  +  +   R A ++ +KE  A R    + +    +Y    
Sbjct: 166 LEQLERKRERERKMREQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDK- 223

Query: 293 GILSNSWKR--------RYH----SRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPE 340
            + ++ W R        R+      + ++ + +++R L+ D   ++  + + S   +   
Sbjct: 224 -VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSA 282

Query: 341 EPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPAL----KQPRERSASRRSSASS 396
           E     EEEEEEEEEEEEE    +  +    E  EE        ++  E+SA   S    
Sbjct: 283 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 342

Query: 397 SDSDEMDYDLELKMI 411
           S+ +E + +  L ++
Sbjct: 343 SEDEERENENHLLVV 357



 Score = 37.4 bits (85), Expect = 0.041
 Identities = 69/306 (22%), Positives = 133/306 (43%), Gaps = 56/306 (18%)

Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVED-------ENSSDVELDTLSQ- 235
           Q+K R ++  E+K+  KR K+  +  S  D  EEGE+ D        NS     D++   
Sbjct: 18  QEKKRRKE-QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76

Query: 236 -VEEESLLRNDLRPANKLAKGNRLFMRFATKDDK-KELGAARRSQYYMKY-GNPNYGGMK 292
             E++SL    ++P  ++++  ++  R   KD+K KE   AR  +   ++     +   +
Sbjct: 77  GEEDDSLA---IKPPQQMSRKEKVHHR---KDEKRKEKKHARVKEKEREHERRKRHREEQ 130

Query: 293 GILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEE 352
                 W+R+      +    ++R   G+D G+  ++ R   L  +  +   E +  E++
Sbjct: 131 DKARREWERQKRREMAREHSRRER---GND-GVCLFRDR---LEQLERKRERERKMREQQ 183

Query: 353 EEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMI- 411
           +E+ E+++++  A++R               +ER A R  SA      E DY  ++K   
Sbjct: 184 KEQREQKERERRAEER--------------RKEREARREVSAHHRTMRE-DYSDKVKASH 228

Query: 412 ---STPSP-----------KKSMKMTMYADEVESQLKNIRNSMR-ADSVSSSNIKNRIGN 456
              S P P           K   +  M   ++ S L++I +S R   S  SS+ ++  G+
Sbjct: 229 WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS 288

Query: 457 KLPPEK 462
           +   E+
Sbjct: 289 EEEEEE 294


>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
          Length = 587

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 26/82 (31%), Positives = 46/82 (56%), Gaps = 4/82 (4%)

Query: 335 LVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSA 394
           L ++ ++  EEEEEE EEEEEE EE+++ D ++    E  EE    ++P++R    +S+ 
Sbjct: 354 LASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEE----EEPQQRGQGEKSAT 409

Query: 395 SSSDSDEMDYDLELKMISTPSP 416
            S    + +      ++S+P P
Sbjct: 410 PSRKILDPNTGEPAPVLSSPPP 431



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 11/33 (33%), Positives = 22/33 (66%)

Query: 191 DASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDE 223
           D  E++  E+ +++ +E+  +D+E EE E E+E
Sbjct: 362 DEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEE 394



 Score = 30.4 bits (67), Expect = 5.1
 Identities = 13/32 (40%), Positives = 20/32 (62%)

Query: 208 DSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239
           D  D++E EEGE E+E + + E +   + EEE
Sbjct: 359 DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEE 390



 Score = 29.6 bits (65), Expect = 8.6
 Identities = 11/43 (25%), Positives = 26/43 (60%)

Query: 187 IRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVE 229
           + S    ED+  E+  ++++E++ +++E +E E E+E   + E
Sbjct: 354 LASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEE 396



 Score = 29.6 bits (65), Expect = 8.6
 Identities = 13/36 (36%), Positives = 20/36 (55%)

Query: 204 DKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239
           D+ E+  ++ E EE E E+E   D E +   + EEE
Sbjct: 360 DEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEE 395


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.126    0.345 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,114,530
Number of Sequences: 37866
Number of extensions: 1329315
Number of successful extensions: 38179
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 628
Number of HSP's successfully gapped in prelim test: 510
Number of HSP's that attempted gapping in prelim test: 14908
Number of HSP's gapped (non-prelim): 11242
length of query: 620
length of database: 18,247,518
effective HSP length: 108
effective length of query: 512
effective length of database: 14,157,990
effective search space: 7248890880
effective search space used: 7248890880
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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