BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|166295179 ELG protein isoform a [Homo sapiens] (620 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|166295179 ELG protein isoform a [Homo sapiens] 1222 0.0 gi|8923771 ELG protein isoform b [Homo sapiens] 676 0.0 gi|210032580 SET domain containing 1B [Homo sapiens] 54 4e-07 gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 54 6e-07 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 52 1e-06 gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 52 2e-06 gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 52 2e-06 gi|17975763 myelin transcription factor 1 [Homo sapiens] 51 4e-06 gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 51 4e-06 gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 51 4e-06 gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo s... 50 5e-06 gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 50 6e-06 gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 50 6e-06 gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 49 1e-05 gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 49 2e-05 gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 49 2e-05 gi|33391150 nucleoplasmin 2 [Homo sapiens] 49 2e-05 gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 48 2e-05 gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 48 2e-05 gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 48 2e-05 gi|122937227 U2-associated SR140 protein [Homo sapiens] 48 2e-05 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 48 3e-05 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 48 3e-05 gi|5803109 osteosarcoma amplified 9 isoform 1 precursor [Homo sa... 47 5e-05 gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 47 5e-05 gi|13376339 plasticity-related protein 2 [Homo sapiens] 47 5e-05 gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 47 5e-05 gi|58761548 tau tubulin kinase 1 [Homo sapiens] 47 7e-05 gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 47 7e-05 gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 47 7e-05 >gi|166295179 ELG protein isoform a [Homo sapiens] Length = 620 Score = 1222 bits (3162), Expect = 0.0 Identities = 620/620 (100%), Positives = 620/620 (100%) Query: 1 MAAVRGLRVSVKAEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRRSLKELI 60 MAAVRGLRVSVKAEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRRSLKELI Sbjct: 1 MAAVRGLRVSVKAEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRRSLKELI 60 Query: 61 PDTSRRYENKAGSFITGIDVTSKEAIEKKEQRAKRFHFRSEVNLAQRNVALDRDMMKKAI 120 PDTSRRYENKAGSFITGIDVTSKEAIEKKEQRAKRFHFRSEVNLAQRNVALDRDMMKKAI Sbjct: 61 PDTSRRYENKAGSFITGIDVTSKEAIEKKEQRAKRFHFRSEVNLAQRNVALDRDMMKKAI 120 Query: 121 PKVRLETIYICGVDEMSTQDVFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSS 180 PKVRLETIYICGVDEMSTQDVFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSS Sbjct: 121 PKVRLETIYICGVDEMSTQDVFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSS 180 Query: 181 LPAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEES 240 LPAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEES Sbjct: 181 LPAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEES 240 Query: 241 LLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWK 300 LLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWK Sbjct: 241 LLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWK 300 Query: 301 RRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEED 360 RRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEED Sbjct: 301 RRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEED 360 Query: 361 QDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSM 420 QDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSM Sbjct: 361 QDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSM 420 Query: 421 KMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPR 480 KMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPR Sbjct: 421 KMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPR 480 Query: 481 PPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREK 540 PPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREK Sbjct: 481 PPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREK 540 Query: 541 KSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLDN 600 KSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLDN Sbjct: 541 KSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLDN 600 Query: 601 LPSLQIEVSRESSSGSEAES 620 LPSLQIEVSRESSSGSEAES Sbjct: 601 LPSLQIEVSRESSSGSEAES 620 >gi|8923771 ELG protein isoform b [Homo sapiens] Length = 340 Score = 676 bits (1744), Expect = 0.0 Identities = 340/340 (100%), Positives = 340/340 (100%) Query: 281 MKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPE 340 MKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPE Sbjct: 1 MKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPE 60 Query: 341 EPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSD 400 EPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSD Sbjct: 61 EPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSD 120 Query: 401 EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPP 460 EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPP Sbjct: 121 EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPP 180 Query: 461 EKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH 520 EKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH Sbjct: 181 EKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH 240 Query: 521 SRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRA 580 SRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRA Sbjct: 241 SRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRA 300 Query: 581 WGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES 620 WGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES Sbjct: 301 WGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES 340 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 53.9 bits (128), Expect = 4e-07 Identities = 37/109 (33%), Positives = 54/109 (49%), Gaps = 14/109 (12%) Query: 337 NVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERS--------- 387 ++ EE EEEEE EEEEEEE+D D D+DDR E +E AL + E+ Sbjct: 1040 SLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEET 1099 Query: 388 ----ASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQ 432 S+ + SSS+S E + E S+PS + + + +E E + Sbjct: 1100 VSIVTSKAEATSSSESSESS-EFESSSESSPSSSEDEEEVVAREEEEEE 1147 Score = 35.0 bits (79), Expect = 0.21 Identities = 40/172 (23%), Positives = 68/172 (39%), Gaps = 34/172 (19%) Query: 344 EEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMD 403 E+EEE EEEEEEE+++M A++ + E+ + A+ A + DS M+ Sbjct: 1133 EDEEEVVAREEEEEEEEEEMVAEESMASAGPEDF----EQDGEEAALAPGAPAVDSLGME 1188 Query: 404 YDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKF 463 ++++ E E+ R SM + ++ ++ PPE+ Sbjct: 1189 EEVDI-------------------ETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEE- 1228 Query: 464 ADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREP 515 L E P PP ++ + P SPE+A + V EP Sbjct: 1229 ---PGLSQEGAMLLSPEPPAKEVEA-------RPPLSPERAPEHDLEVEPEP 1270 Score = 33.9 bits (76), Expect = 0.46 Identities = 13/48 (27%), Positives = 30/48 (62%) Query: 192 ASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239 + E +S E+ ++ ++E+ +DD+ ++ + DE+ +D E LS+ E+ Sbjct: 1042 SEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEK 1089 Score = 29.6 bits (65), Expect = 8.6 Identities = 13/55 (23%), Positives = 29/55 (52%), Gaps = 1/55 (1%) Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEE 238 ++ + S ++ E +++++ED DDD + E E+++ D L S+ +E Sbjct: 1038 KESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDD-EDTALSEASEKDE 1091 Score = 29.6 bits (65), Expect = 8.6 Identities = 15/59 (25%), Positives = 30/59 (50%) Query: 183 AQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESL 241 ++++ + + E + E+ + D +DS D DE+E + + S E D EEE++ Sbjct: 1042 SEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETV 1100 >gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] Length = 330 Score = 53.5 bits (127), Expect = 6e-07 Identities = 47/196 (23%), Positives = 88/196 (44%), Gaps = 11/196 (5%) Query: 314 KKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEY 373 KK+ G VG S L V ++ E EEE+E+E+ + + D+D D DD + +Y Sbjct: 130 KKKKYRGKAVGPASI------LKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKY 183 Query: 374 HEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQL 433 + + + ++ ++RRS + S S S+ S +S + + + S+ Sbjct: 184 NLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRS 243 Query: 434 KNIRNSMRADSVSSSNIKNRIGNKLPPEK-FADVRHLLDEKRQHSRPRPPVSSTKSDIRQ 492 + S S S S+ ++ G+ P ++ ++ + R+ SR R S+ S R+ Sbjct: 244 SSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSR----SSSSGDRK 299 Query: 493 RLGKRPHSPEKAFSSN 508 + R SPE+ S+ Sbjct: 300 KRRTRSRSPERRHRSS 315 Score = 30.0 bits (66), Expect = 6.6 Identities = 48/206 (23%), Positives = 75/206 (36%), Gaps = 35/206 (16%) Query: 194 EDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLRNDLRPANKLA 253 EDK +E ++D+ ED S + + E EDE+ +D+ L EEE +NK Sbjct: 149 EDKESEGEEEDEDEDLS---KYKLDEDEDEDDADLSKYNLDASEEED--------SNK-K 196 Query: 254 KGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVI 313 K NR R +K ++ RS + + + S+ + R SR R Sbjct: 197 KSNR---RSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRS-- 251 Query: 314 KKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEY 373 G +S HR S + P + E + + + DR Sbjct: 252 -----RGSKSRSSSRSHRGS---SSPRKRSYSSSSSSPERNRKRSRSRSSSSGDR----- 298 Query: 374 HEELPALKQPRERSASRRSSASSSDS 399 ++ R RS RR +SS S Sbjct: 299 -----KKRRTRSRSPERRHRSSSGSS 319 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 52.4 bits (124), Expect = 1e-06 Identities = 27/72 (37%), Positives = 39/72 (54%) Query: 336 VNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSAS 395 +N +E EEEEEEEEEEEEEEEE++D + ++ EY EE ++ E Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGEL 942 Query: 396 SSDSDEMDYDLE 407 + +E D + E Sbjct: 943 EEEEEEEDEEEE 954 Score = 45.1 bits (105), Expect = 2e-04 Identities = 23/68 (33%), Positives = 36/68 (52%) Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDS 399 EE EEEEEEEEEEEEEE+ +++ + ++ E EE ++ E + Sbjct: 891 EEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEED 950 Query: 400 DEMDYDLE 407 +E + +LE Sbjct: 951 EEEEEELE 958 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 1/68 (1%) Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDS 399 EE EEEEEEE+ EEEEE+E++ + ++ E+ EE + E + Sbjct: 898 EEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEEL 957 Query: 400 DEMDYDLE 407 +E++ DLE Sbjct: 958 EEVE-DLE 964 Score = 35.8 bits (81), Expect = 0.12 Identities = 16/34 (47%), Positives = 25/34 (73%) Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEY 373 EE EEEE E EEEEEEE+E+++ + ++ +E+ Sbjct: 932 EEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEF 965 Score = 33.5 bits (75), Expect = 0.60 Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 2/67 (2%) Query: 175 LINMSSLPAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDE--AEEGEVEDENSSDVELDT 232 +IN++S +++ + E++ E+ ++D +E+ D++E EE E E+E + E + Sbjct: 880 VININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEE 939 Query: 233 LSQVEEE 239 EEE Sbjct: 940 GELEEEE 946 >gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] Length = 320 Score = 52.0 bits (123), Expect = 2e-06 Identities = 46/190 (24%), Positives = 85/190 (44%), Gaps = 11/190 (5%) Query: 314 KKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEY 373 KK+ G VG S L V ++ E EEE+E+E+ + + D+D D DD + +Y Sbjct: 130 KKKKYRGKAVGPASI------LKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKY 183 Query: 374 HEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQL 433 + + + ++ ++RRS + S S S+ S +S + + + S+ Sbjct: 184 NLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRS 243 Query: 434 KNIRNSMRADSVSSSNIKNRIGNKLPPEK-FADVRHLLDEKRQHSRPRPPVSSTKSDIRQ 492 + S S S S+ ++ G+ P ++ ++ + R+ SR R S+ S R+ Sbjct: 244 SSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSR----SSSSGDRK 299 Query: 493 RLGKRPHSPE 502 + R SPE Sbjct: 300 KRRTRSRSPE 309 >gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens] Length = 1341 Score = 51.6 bits (122), Expect = 2e-06 Identities = 61/239 (25%), Positives = 95/239 (39%), Gaps = 38/239 (15%) Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVV----EYHEELPALK-------QPRERSA 388 EE EEEEEEEE++EEEE +D+ + + ++ E EE+P +K +P+ RS Sbjct: 270 EEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQ 329 Query: 389 SRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSS 448 + + ++ +K MK T +E E ++K SS Sbjct: 330 EQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIK-----------SSQ 378 Query: 449 NIKNRIGNKLPPEKFADVRH----LLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKA 504 +K + + PP D + L E+ PP TK + HS E+ Sbjct: 379 GLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPPPHPQLHSEEEI 438 Query: 505 FSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKKSGNLWTRL--GSAPKTKEKNTK 561 P+ P+ V +L P D ADTRE +L G +P + +TK Sbjct: 439 ---EPM--EGPAPPVLIQLSPPNTD-----ADTRELLVSQHTVQLVGGLSPLSSPSDTK 487 Score = 35.8 bits (81), Expect = 0.12 Identities = 102/507 (20%), Positives = 186/507 (36%), Gaps = 97/507 (19%) Query: 171 ATRALINMSSLPAQDK------IRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDEN 224 A A ++ S PA+++ R+ D++ + +++++E+ ++D+ EE E +DE Sbjct: 234 ARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEE-EGDDEG 292 Query: 225 SSDVELDTLSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKEL----GAARRSQYY 280 E L + +EE ++P + + R T+ ++E+ G RSQ Sbjct: 293 QKSREAPILKEFKEEGEEIPRVKPEEMMDE------RPKTRSQEQEVLERGGRFTRSQEE 346 Query: 281 MKYGNPNYGGMKGILSNSWKRRYHSRRIQRDV-IKKRALIGDDVGLTSYKHRHSGLVNVP 339 + + + + + R I+ +K+++ LT + + S LV +P Sbjct: 347 ARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKAS-LVALP 405 Query: 340 EEPIEEEE--------------------EEEEEEEEE--------EEEDQDMDADDR-VV 370 E+ EEE EEE E E + + DAD R ++ Sbjct: 406 EQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEPMEGPAPPVLIQLSPPNTDADTRELL 465 Query: 371 VEYH------------------EELPALKQPRERSASRRSSASSSD-SDEMDYDLELKMI 411 V H E PA K P E ++ +D S + D + E Sbjct: 466 VSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEESVLPLVQKSTLADYSAQKDLEPESDRS 525 Query: 412 STPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLD 471 + P P K ++ + E LK + +S + K + + Sbjct: 526 AQPLPLKIEELALAKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSS 585 Query: 472 EKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSK 531 SR R P SS G R HSP ++ + R ++ G P+ S+ Sbjct: 586 SSSSRSRSRSPDSS---------GSRSHSPLRSKQRDVAQARTHANP----RGRPKMGSR 632 Query: 532 GLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQS 591 T E +S R S ++ N++K +PG D S + + K+ S Sbjct: 633 ----STSESRS-----RSRSRSRSASSNSRK--SLSPGVSRDSST------SYTETKDPS 675 Query: 592 RQKKSRLDNLPSLQIEVSRESSSGSEA 618 ++ +P LQ+ +E +S S + Sbjct: 676 SGQEVATPPVPQLQVCEPKERTSTSSS 702 Score = 30.0 bits (66), Expect = 6.6 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 6/85 (7%) Query: 338 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRE----RSASRRSS 393 VP E E + EEEEEE+E E + + +V VE PA + ++ + +RRS Sbjct: 925 VPAEGQENGQREEEEEEKEPEAEPPV--PPQVSVEVALPPPAEHEVKKVTLGDTLTRRSI 982 Query: 394 ASSSDSDEMDYDLELKMISTPSPKK 418 + + D ++ PSP + Sbjct: 983 SQQKSGVSITIDDPVRTAQVPSPPR 1007 Score = 29.6 bits (65), Expect = 8.6 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 7/57 (12%) Query: 344 EEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSD 400 EEEE++E E+E E E ++ ++ + R E+ E + RER R D D Sbjct: 1256 EEEEQKEREKEAERERNRQLEREKR--REHSRE-----RDRERERERERDRGDRDRD 1305 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 50.8 bits (120), Expect = 4e-06 Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 3/126 (2%) Query: 331 RHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASR 390 + G+++ EE EEEEEEEEEEE+EEEE+++ + ++ E EE ++ E A+ Sbjct: 250 KQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309 Query: 391 R---SSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSS 447 +S S + +L +P P+ S+ + + +D+ + + + R S D Sbjct: 310 DVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEM 369 Query: 448 SNIKNR 453 ++ R Sbjct: 370 QDMMTR 375 Score = 36.6 bits (83), Expect = 0.071 Identities = 15/46 (32%), Positives = 29/46 (63%) Query: 194 EDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239 ED+ E+ +++++ED +++E EE E E+E + E + + EEE Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305 Score = 36.2 bits (82), Expect = 0.092 Identities = 23/118 (19%), Positives = 55/118 (46%), Gaps = 9/118 (7%) Query: 167 DEMTATRALINMSSLPAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSS 226 +E + + +++ +++ + ED+ E+ +++++E+ +++E EE E E+E Sbjct: 246 EESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305 Query: 227 DVELDTLSQ-------VEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRS 277 + D + Q ++ LR P+ K + + + DDK E +R+S Sbjct: 306 EAAPDVIFQEDTSHTSAQKAPELRGPESPSPK--PEYSVIVEVRSDDDKDEDTHSRKS 361 Score = 34.7 bits (78), Expect = 0.27 Identities = 17/48 (35%), Positives = 27/48 (56%) Query: 192 ASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239 ASE+ S +K +E+ +++E EE E EDE + E + + EEE Sbjct: 244 ASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEE 291 Score = 33.1 bits (74), Expect = 0.78 Identities = 14/51 (27%), Positives = 29/51 (56%) Query: 189 SRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239 S ++S+ K +++ +E+ +++E EE E E+E + E + + EEE Sbjct: 245 SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEE 295 Score = 32.3 bits (72), Expect = 1.3 Identities = 12/63 (19%), Positives = 34/63 (53%) Query: 177 NMSSLPAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQV 236 ++ +++ + + + ++ +++++E+ +D+E EE E E+E + E + + Sbjct: 239 SLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEE 298 Query: 237 EEE 239 EEE Sbjct: 299 EEE 301 >gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9 [Homo sapiens] Length = 771 Score = 50.8 bits (120), Expect = 4e-06 Identities = 54/246 (21%), Positives = 105/246 (42%), Gaps = 21/246 (8%) Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVED--ENSSDVELDTLSQVEEESL 241 ++K +R +++ E+RK+ ++E E E + + S E D L Q+E + Sbjct: 106 KEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRE 165 Query: 242 LRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKR 301 +R K + + R A ++ +KE A R + + +Y + ++ W R Sbjct: 166 RERKMREQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDK--VKASHWSR 222 Query: 302 --------RYH----SRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEE 349 R+ + ++ + +++R L+ D ++ + + S + E EEE Sbjct: 223 SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 282 Query: 350 EEEEEEEEEEDQDMDADDRVVVEYHEELPAL----KQPRERSASRRSSASSSDSDEMDYD 405 EEEEEEEEEE + + E EE ++ E+SA S S+ +E + + Sbjct: 283 EEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 342 Query: 406 LELKMI 411 L ++ Sbjct: 343 NHLLVV 348 Score = 40.0 bits (92), Expect = 0.006 Identities = 66/266 (24%), Positives = 114/266 (42%), Gaps = 47/266 (17%) Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVED-------ENSSDVELDTLSQ- 235 Q+K R ++ E+K+ KR K+ + S D EEGE+ D NS D++ Sbjct: 18 QEKKRRKE-QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76 Query: 236 -VEEESLLRNDLRPANKLAKGNRLFMRFATKDDK-KELGAARRSQYYMKY-GNPNYGGMK 292 E++SL ++P ++++ ++ R KD+K KE AR + ++ + + Sbjct: 77 GEEDDSLA---IKPPQQMSRKEKVHHR---KDEKRKEKKHARVKEKEREHERRKRHREEQ 130 Query: 293 GILSNSWKR-------RYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEE 345 W+R R HSRR +RD +++ L + R + +E E+ Sbjct: 131 DKARREWERQKRREMAREHSRR-ERDRLEQ---------LERKRERERKMREQQKEQREQ 180 Query: 346 EEEEE--EEEEEEEEEDQDMDADDRVVVE-YHEELPAL-------KQPRER--SASRRSS 393 +E E EE +E E +++ A R + E Y +++ A + PRER R Sbjct: 181 KERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKP 240 Query: 394 ASSSDSDEMDYDLELKMISTPSPKKS 419 +E D +L+ IS K S Sbjct: 241 VKEEKMEERDLLSDLQDISDSERKTS 266 >gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4 [Homo sapiens] Length = 737 Score = 50.8 bits (120), Expect = 4e-06 Identities = 54/246 (21%), Positives = 105/246 (42%), Gaps = 21/246 (8%) Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVED--ENSSDVELDTLSQVEEESL 241 ++K +R +++ E+RK+ ++E E E + + S E D L Q+E + Sbjct: 72 KEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRE 131 Query: 242 LRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKR 301 +R K + + R A ++ +KE A R + + +Y + ++ W R Sbjct: 132 RERKMREQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDK--VKASHWSR 188 Query: 302 --------RYH----SRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEE 349 R+ + ++ + +++R L+ D ++ + + S + E EEE Sbjct: 189 SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 248 Query: 350 EEEEEEEEEEDQDMDADDRVVVEYHEELPAL----KQPRERSASRRSSASSSDSDEMDYD 405 EEEEEEEEEE + + E EE ++ E+SA S S+ +E + + Sbjct: 249 EEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 308 Query: 406 LELKMI 411 L ++ Sbjct: 309 NHLLVV 314 >gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo sapiens] Length = 652 Score = 50.4 bits (119), Expect = 5e-06 Identities = 59/246 (23%), Positives = 95/246 (38%), Gaps = 37/246 (15%) Query: 344 EEEEEEEEEEEEEEEEDQDMDADDRVVV-EYHEELPALKQPRERSASRRSSASSSDSDEM 402 + E + E EEEE+E+ED+D D D+R ++ E+ +EL + P +R R + D D + Sbjct: 406 DPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGL 465 Query: 403 DYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEK 462 + E + M + +K + + V K + K PP Sbjct: 466 KKESE----------RDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPS- 514 Query: 463 FADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGK-RPHSPEKAFSSNPVVRREPSSDVHS 521 P+P + +R R+ K R P + + + R P Sbjct: 515 ----------------PQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIE 558 Query: 522 RLGVPRQDSKGLYADTR-EKKSGNLW---TRLGSAPKTKE--KNTKKV--DHRAPGAEED 573 L + +GL A + E K W T G+ T E +N K++ + PGAEE Sbjct: 559 GLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEEA 618 Query: 574 DSELQR 579 E QR Sbjct: 619 QKERQR 624 >gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5 [Homo sapiens] Length = 748 Score = 50.1 bits (118), Expect = 6e-06 Identities = 51/240 (21%), Positives = 101/240 (42%), Gaps = 19/240 (7%) Query: 188 RSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLRNDLR 247 R ++ + KR +++Q+ + + E ++ S E D L Q+E + +R Sbjct: 89 RVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR 148 Query: 248 PANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKR------ 301 K + + R A ++ +KE A R + + +Y + ++ W R Sbjct: 149 EQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDK--VKASHWSRSPPRPP 205 Query: 302 --RYH----SRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEE 355 R+ + ++ + +++R L+ D ++ + + S + E EEEEEEEEE Sbjct: 206 RERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE 265 Query: 356 EEEEDQDMDADDRVVVEYHEELPAL----KQPRERSASRRSSASSSDSDEMDYDLELKMI 411 EEEE + + E EE ++ E+SA S S+ +E + + L ++ Sbjct: 266 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 325 Score = 34.3 bits (77), Expect = 0.35 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 6/62 (9%) Query: 185 DKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEG------EVEDENSSDVELDTLSQVEE 238 D R ++E SAE ++E+ +++E EEG E E+E + E +T S EE Sbjct: 237 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 296 Query: 239 ES 240 S Sbjct: 297 AS 298 >gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform 2 [Homo sapiens] Length = 782 Score = 50.1 bits (118), Expect = 6e-06 Identities = 51/240 (21%), Positives = 101/240 (42%), Gaps = 19/240 (7%) Query: 188 RSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLRNDLR 247 R ++ + KR +++Q+ + + E ++ S E D L Q+E + +R Sbjct: 123 RVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR 182 Query: 248 PANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKR------ 301 K + + R A ++ +KE A R + + +Y + ++ W R Sbjct: 183 EQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDK--VKASHWSRSPPRPP 239 Query: 302 --RYH----SRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEE 355 R+ + ++ + +++R L+ D ++ + + S + E EEEEEEEEE Sbjct: 240 RERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE 299 Query: 356 EEEEDQDMDADDRVVVEYHEELPAL----KQPRERSASRRSSASSSDSDEMDYDLELKMI 411 EEEE + + E EE ++ E+SA S S+ +E + + L ++ Sbjct: 300 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 359 Score = 40.4 bits (93), Expect = 0.005 Identities = 69/304 (22%), Positives = 124/304 (40%), Gaps = 50/304 (16%) Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVED-------ENSSDVELDTLSQ- 235 Q+K R ++ E+K+ KR K+ + S D EEGE+ D NS D++ Sbjct: 18 QEKKRRKE-QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76 Query: 236 -VEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGI 294 E++SL ++P ++++ ++ R KD+K++ RS + G K Sbjct: 77 GEEDDSLA---IKPPQQMSRKEKVHHR---KDEKRKEKRRHRSH--------SAEGGKHA 122 Query: 295 LSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEE 354 +R + R+ R+ K + HS E +E + E E + Sbjct: 123 RVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR 182 Query: 355 EEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMI--- 411 E+++E ++ + E A ++ +ER A R SA E DY ++K Sbjct: 183 EQQKEQRE---------QKERERRAEERRKEREARREVSAHHRTMRE-DYSDKVKASHWS 232 Query: 412 -STPSP-----------KKSMKMTMYADEVESQLKNIRNSMR-ADSVSSSNIKNRIGNKL 458 S P P K + M ++ S L++I +S R S SS+ ++ G++ Sbjct: 233 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE 292 Query: 459 PPEK 462 E+ Sbjct: 293 EEEE 296 Score = 34.3 bits (77), Expect = 0.35 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 6/62 (9%) Query: 185 DKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEG------EVEDENSSDVELDTLSQVEE 238 D R ++E SAE ++E+ +++E EEG E E+E + E +T S EE Sbjct: 271 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 330 Query: 239 ES 240 S Sbjct: 331 AS 332 Score = 29.6 bits (65), Expect = 8.6 Identities = 61/291 (20%), Positives = 112/291 (38%), Gaps = 23/291 (7%) Query: 341 EPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSD 400 + I +E++ +E+EE+ E + ++DDR E L+ R R S DS Sbjct: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSM 73 Query: 401 EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRN-SMRADSVSSSNIKNR----IG 455 E + + + P + S K ++ + E + + R+ S A+ + +K + Sbjct: 74 EDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHER 133 Query: 456 NKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHS---PEKAFSSNPVVR 512 K E+ R + +++ R + + Q KR E+ Sbjct: 134 RKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE 193 Query: 513 REPSSDVHSRLGVPRQDSKGLYADTRE----KKSGNLWTRLGSAPKTKEKNTKKVDHRAP 568 RE ++ + R++ + RE K + W+R S P+ + + D R P Sbjct: 194 RERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSR--SPPRPPRERFELGDGRKP 251 Query: 569 GAEEDDSELQRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAE 619 EE E R + +++ S +K S ++ S ES SGSE E Sbjct: 252 VKEEKMEE--RDLLSDLQDISDSERKTSSAES-------SSAESGSGSEEE 293 >gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] Length = 709 Score = 49.3 bits (116), Expect = 1e-05 Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 12/126 (9%) Query: 338 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSA--------S 389 V E+ EEEEEEEEEEEEEEEE+++ + D+R E + + + + S Sbjct: 225 VDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGS 284 Query: 390 RRSSASSSDSDEMDYDLELKMISTP---SPKKSMKMTMYADEVESQLKNIRNSMRADSVS 446 RS + + SDE + + +P S YAD+ S+LK + R + Sbjct: 285 VRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYADQT-SKLKYVLQDARFFLIK 343 Query: 447 SSNIKN 452 S+N +N Sbjct: 344 SNNHEN 349 Score = 43.1 bits (100), Expect = 8e-04 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 4/84 (4%) Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDS 399 EE +EE+ EE+EE EE+ EED+++D D E EE ++ E D Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEE----EEEEEEEEEEEYEQDERDQ 257 Query: 400 DEMDYDLELKMISTPSPKKSMKMT 423 E D + + ++ S +S+ T Sbjct: 258 KEEGNDYDTRSEASDSGSESVSFT 281 Score = 42.0 bits (97), Expect = 0.002 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 8/98 (8%) Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDS 399 EE EE+EE +E+ EEEEEE+++ + ++ E +E+ ++ RS AS S S Sbjct: 216 EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGS 275 Query: 400 DEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIR 437 + + + T +S T +DE + + K R Sbjct: 276 ESVSF--------TDGSVRSGSGTDGSDEKKKERKRAR 305 Score = 32.3 bits (72), Expect = 1.3 Identities = 15/49 (30%), Positives = 25/49 (51%) Query: 191 DASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239 D ED+ E+ ++ +E D +E EE E E+E + E + Q E + Sbjct: 208 DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERD 256 Score = 29.6 bits (65), Expect = 8.6 Identities = 16/69 (23%), Positives = 33/69 (47%), Gaps = 8/69 (11%) Query: 179 SSLPAQDKIRSRDASEDKSA--------EKRKKDKQEDSSDDDEAEEGEVEDENSSDVEL 230 SS +++++ S + D + + +E+ ++D E+ EVE++ D E+ Sbjct: 166 SSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEV 225 Query: 231 DTLSQVEEE 239 D + EEE Sbjct: 226 DEDGEEEEE 234 >gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] Length = 770 Score = 48.5 bits (114), Expect = 2e-05 Identities = 51/239 (21%), Positives = 100/239 (41%), Gaps = 19/239 (7%) Query: 189 SRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLRNDLRP 248 +R + KR +++Q+ + + E ++ S E D L Q+E + +R Sbjct: 112 ARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMRE 171 Query: 249 ANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKR------- 301 K + + R A ++ +KE A R + + +Y + ++ W R Sbjct: 172 QQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDK--VKASHWSRSPPRPPR 228 Query: 302 -RYH----SRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEE 356 R+ + ++ + +++R L+ D ++ + + S + E EEEEEEEEEE Sbjct: 229 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 288 Query: 357 EEEDQDMDADDRVVVEYHEELPAL----KQPRERSASRRSSASSSDSDEMDYDLELKMI 411 EEE + + E EE ++ E+SA S S+ +E + + L ++ Sbjct: 289 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 347 Score = 39.7 bits (91), Expect = 0.008 Identities = 65/265 (24%), Positives = 111/265 (41%), Gaps = 46/265 (17%) Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVED-------ENSSDVELDTLSQ- 235 Q+K R ++ E+K+ KR K+ + S D EEGE+ D NS D++ Sbjct: 18 QEKKRRKE-QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76 Query: 236 -VEEESLLRNDLRPANKLAKGNRLFMRFATKDDK-KELGAARRSQYYMKYGNPNYGGMKG 293 E++SL ++P ++++ ++ R KD+K KE R + + + Sbjct: 77 GEEDDSLA---IKPPQQMSRKEKVHHR---KDEKRKEKWKHARVKEREHERRKRHREEQD 130 Query: 294 ILSNSWKR-------RYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEE 346 W+R R HSRR +RD +++ L + R + +E E++ Sbjct: 131 KARREWERQKRREMAREHSRR-ERDRLEQ---------LERKRERERKMREQQKEQREQK 180 Query: 347 EEEE--EEEEEEEEEDQDMDADDRVVVE-YHEELPAL-------KQPRER--SASRRSSA 394 E E EE +E E +++ A R + E Y +++ A + PRER R Sbjct: 181 ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 240 Query: 395 SSSDSDEMDYDLELKMISTPSPKKS 419 +E D +L+ IS K S Sbjct: 241 KEEKMEERDLLSDLQDISDSERKTS 265 Score = 34.3 bits (77), Expect = 0.35 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 6/62 (9%) Query: 185 DKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEG------EVEDENSSDVELDTLSQVEE 238 D R ++E SAE ++E+ +++E EEG E E+E + E +T S EE Sbjct: 259 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 318 Query: 239 ES 240 S Sbjct: 319 AS 320 >gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] Length = 780 Score = 48.5 bits (114), Expect = 2e-05 Identities = 51/239 (21%), Positives = 100/239 (41%), Gaps = 19/239 (7%) Query: 189 SRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLRNDLRP 248 +R + KR +++Q+ + + E ++ S E D L Q+E + +R Sbjct: 122 ARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMRE 181 Query: 249 ANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKR------- 301 K + + R A ++ +KE A R + + +Y + ++ W R Sbjct: 182 QQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDK--VKASHWSRSPPRPPR 238 Query: 302 -RYH----SRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEE 356 R+ + ++ + +++R L+ D ++ + + S + E EEEEEEEEEE Sbjct: 239 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 298 Query: 357 EEEDQDMDADDRVVVEYHEELPAL----KQPRERSASRRSSASSSDSDEMDYDLELKMI 411 EEE + + E EE ++ E+SA S S+ +E + + L ++ Sbjct: 299 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 357 Score = 38.1 bits (87), Expect = 0.024 Identities = 67/304 (22%), Positives = 125/304 (41%), Gaps = 52/304 (17%) Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVED-------ENSSDVELDTLSQ- 235 Q+K R ++ E+K+ KR K+ + S D EEGE+ D NS D++ Sbjct: 18 QEKKRRKE-QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76 Query: 236 -VEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGI 294 E++SL ++P ++++ ++ R KD+K++ K + ++ G Sbjct: 77 GEEDDSLA---IKPPQQMSRKEKVHHR---KDEKRK----------EKCRHHSHSAEGGK 120 Query: 295 LSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEE 354 + +R + R+ R+ K + HS E +E + E E + Sbjct: 121 HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR 180 Query: 355 EEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMI--- 411 E+++E ++ + E A ++ +ER A R SA E DY ++K Sbjct: 181 EQQKEQRE---------QKERERRAEERRKEREARREVSAHHRTMRE-DYSDKVKASHWS 230 Query: 412 -STPSP-----------KKSMKMTMYADEVESQLKNIRNSMR-ADSVSSSNIKNRIGNKL 458 S P P K + M ++ S L++I +S R S SS+ ++ G++ Sbjct: 231 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE 290 Query: 459 PPEK 462 E+ Sbjct: 291 EEEE 294 Score = 34.3 bits (77), Expect = 0.35 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 6/62 (9%) Query: 185 DKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEG------EVEDENSSDVELDTLSQVEE 238 D R ++E SAE ++E+ +++E EEG E E+E + E +T S EE Sbjct: 269 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 328 Query: 239 ES 240 S Sbjct: 329 AS 330 Score = 32.0 bits (71), Expect = 1.7 Identities = 63/294 (21%), Positives = 115/294 (39%), Gaps = 31/294 (10%) Query: 341 EPIEEEEEEEEEEEEEEEEDQDMDADD----RVVVEYHEELPALKQPRERSASRRSSASS 396 + I +E++ +E+EE+ E + ++DD R +E E + R++ R S Sbjct: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSM 73 Query: 397 SDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIR-NSMRADSVSSSNIKNRIG 455 D E D L +K P + S K ++ + E + + R +S A+ + +K R Sbjct: 74 EDRGEEDDSLAIK----PPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKEREH 129 Query: 456 NKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREP 515 + + + + +RQ R S + R +R E+ +RE Sbjct: 130 ERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQRE- 188 Query: 516 SSDVHSRLGVPRQDSKG----------LYADTREKKSGNLWTRLGSAPKTKEKNTKKVDH 565 + R R++ + + D +K + W+R S P+ + + D Sbjct: 189 QKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSR--SPPRPPRERFELGDG 246 Query: 566 RAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAE 619 R P EE E R + +++ S +K S ++ S ES SGSE E Sbjct: 247 RKPVKEEKMEE--RDLLSDLQDISDSERKTSSAES-------SSAESGSGSEEE 291 >gi|33391150 nucleoplasmin 2 [Homo sapiens] Length = 214 Score = 48.5 bits (114), Expect = 2e-05 Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 5/83 (6%) Query: 344 EEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMD 403 EEEEEE EEEEEEEE+D+D DAD + EE +KQ + +++S + E + Sbjct: 130 EEEEEEGEEEEEEEEDDEDEDADISL-----EEQSPVKQVKRLVPQKQASVAKKKKLEKE 184 Query: 404 YDLELKMISTPSPKKSMKMTMYA 426 + + SP K K T A Sbjct: 185 EEEIRASVRDKSPVKKAKATARA 207 >gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 48.1 bits (113), Expect = 2e-05 Identities = 94/482 (19%), Positives = 196/482 (40%), Gaps = 88/482 (18%) Query: 172 TRALINMSSLPA--QDKIRSRDASEDKSAEKRKKDKQ-----EDSSDDDEAEEGEVEDEN 224 ++ ++ SLPA Q R R +++ ++R DK E++S + + GE +++ Sbjct: 847 SKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKS 906 Query: 225 SSDVELDTLSQVEEESLLRNDLRPAN-------------------------------KLA 253 + E T S EE L+ ++ +P+ +L Sbjct: 907 EATQEQYTES---EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLT 963 Query: 254 KGNRLFMRFATKDDKKEL-GAARRSQYYMKYGNPNYGGMKGILSNSWKRR----YHSRRI 308 +G+ R ++ D+ L G + S+ + +P + + KR+ + RR+ Sbjct: 964 EGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRV 1023 Query: 309 QRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEE-----EEEEEEEEEDQDM 363 ++ +++ + + T+ V +EP E+ + E E E +EE+++ Sbjct: 1024 RKRKHHNSSVVTETISETT---------EVLDEPFEDSDSERPMPRLEPTFEIDEEEEEE 1074 Query: 364 DADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPS--PKKSMK 421 D ++ EY L + R +S+S+R S + +E D + ++ S K+ +K Sbjct: 1075 DENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVK 1134 Query: 422 MTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRP 481 + + + LK + + S + K R G K P K + R ++ Q P Sbjct: 1135 NSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRK-PGFKLS--REIMPVSTQACVIEP 1191 Query: 482 PVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKK 541 VS K+ G++P E S V EP D+ L R++ + + A+ E + Sbjct: 1192 IVSIPKA------GRKPKIQE---SEETV---EPKEDM--PLPEERKEEEEMQAEAEEAE 1237 Query: 542 SGN----LWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSR 597 G + + +A N+ + + + P EE++ + + + +E+ QS +++ Sbjct: 1238 EGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPR-----VSEEQRQSEEEQQE 1292 Query: 598 LD 599 L+ Sbjct: 1293 LE 1294 Score = 39.7 bits (91), Expect = 0.008 Identities = 65/282 (23%), Positives = 97/282 (34%), Gaps = 60/282 (21%) Query: 338 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 397 +PEE EEEE + E EE EE E++D + E+PA S A SS Sbjct: 1219 LPEERKEEEEMQAEAEEAEEGEEEDAASS---------EVPAA-----------SPADSS 1258 Query: 398 DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNK 457 +S E + T P+ E E + + R ++ Sbjct: 1259 NSPETE---------TKEPEV---------EEEEEKPRVSEEQRQSEEEQQELEEP---- 1296 Query: 458 LPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSS 517 PE+ D + H +S ++ L ++P + V+ EP Sbjct: 1297 -EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRED--------VKEEP-- 1345 Query: 518 DVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSEL 577 GV +REK T L S + +T V + G+E+D E Sbjct: 1346 ------GVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEED 1399 Query: 578 QRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAE 619 LI+ KE+ S LD L ++Q S SE E Sbjct: 1400 SHTKEELIELKEEEEIPHSELD-LETVQAVQSLTQEESSEHE 1440 Score = 38.1 bits (87), Expect = 0.024 Identities = 65/307 (21%), Positives = 122/307 (39%), Gaps = 49/307 (15%) Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDV------------ELD 231 Q+ + + ED + +K+++E ++ +EAEEGE ED SS+V E + Sbjct: 1205 QESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETE 1264 Query: 232 TLS-QVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGG 290 T +VEEE R + + + + ++E AA + + + Sbjct: 1265 TKEPEVEEEE---EKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDD 1321 Query: 291 MKGILSNSWKRRYHSRRIQRDVI---------------KKRALIGD--DVGLTSYKHRHS 333 G L ++ K+ + + DV K R I D + L S + + S Sbjct: 1322 --GHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPS 1379 Query: 334 GLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSS 393 +V E + E++ EE+ +EE ++ ++ + H EL L+ + + + Sbjct: 1380 HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIP---HSELD-LETVQAVQSLTQEE 1435 Query: 394 ASSSDSDEMDYDLELKMIST--------PSPKKSMKMTMYADEVESQLKNIRN--SMRAD 443 +S + D + L T P+ SM +A E S + ++++ S Sbjct: 1436 SSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVR 1495 Query: 444 SVSSSNI 450 SVSS N+ Sbjct: 1496 SVSSPNV 1502 >gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 48.1 bits (113), Expect = 2e-05 Identities = 94/482 (19%), Positives = 196/482 (40%), Gaps = 88/482 (18%) Query: 172 TRALINMSSLPA--QDKIRSRDASEDKSAEKRKKDKQ-----EDSSDDDEAEEGEVEDEN 224 ++ ++ SLPA Q R R +++ ++R DK E++S + + GE +++ Sbjct: 847 SKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKS 906 Query: 225 SSDVELDTLSQVEEESLLRNDLRPAN-------------------------------KLA 253 + E T S EE L+ ++ +P+ +L Sbjct: 907 EATQEQYTES---EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLT 963 Query: 254 KGNRLFMRFATKDDKKEL-GAARRSQYYMKYGNPNYGGMKGILSNSWKRR----YHSRRI 308 +G+ R ++ D+ L G + S+ + +P + + KR+ + RR+ Sbjct: 964 EGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRV 1023 Query: 309 QRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEE-----EEEEEEEEEDQDM 363 ++ +++ + + T+ V +EP E+ + E E E +EE+++ Sbjct: 1024 RKRKHHNSSVVTETISETT---------EVLDEPFEDSDSERPMPRLEPTFEIDEEEEEE 1074 Query: 364 DADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPS--PKKSMK 421 D ++ EY L + R +S+S+R S + +E D + ++ S K+ +K Sbjct: 1075 DENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVK 1134 Query: 422 MTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRP 481 + + + LK + + S + K R G K P K + R ++ Q P Sbjct: 1135 NSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRK-PGFKLS--REIMPVSTQACVIEP 1191 Query: 482 PVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKK 541 VS K+ G++P E S V EP D+ L R++ + + A+ E + Sbjct: 1192 IVSIPKA------GRKPKIQE---SEETV---EPKEDM--PLPEERKEEEEMQAEAEEAE 1237 Query: 542 SGN----LWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSR 597 G + + +A N+ + + + P EE++ + + + +E+ QS +++ Sbjct: 1238 EGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPR-----VSEEQRQSEEEQQE 1292 Query: 598 LD 599 L+ Sbjct: 1293 LE 1294 Score = 39.7 bits (91), Expect = 0.008 Identities = 65/282 (23%), Positives = 97/282 (34%), Gaps = 60/282 (21%) Query: 338 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 397 +PEE EEEE + E EE EE E++D + E+PA S A SS Sbjct: 1219 LPEERKEEEEMQAEAEEAEEGEEEDAASS---------EVPAA-----------SPADSS 1258 Query: 398 DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNK 457 +S E + T P+ E E + + R ++ Sbjct: 1259 NSPETE---------TKEPEV---------EEEEEKPRVSEEQRQSEEEQQELEEP---- 1296 Query: 458 LPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSS 517 PE+ D + H +S ++ L ++P + V+ EP Sbjct: 1297 -EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRED--------VKEEP-- 1345 Query: 518 DVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSEL 577 GV +REK T L S + +T V + G+E+D E Sbjct: 1346 ------GVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEED 1399 Query: 578 QRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAE 619 LI+ KE+ S LD L ++Q S SE E Sbjct: 1400 SHTKEELIELKEEEEIPHSELD-LETVQAVQSLTQEESSEHE 1440 Score = 38.1 bits (87), Expect = 0.024 Identities = 65/307 (21%), Positives = 122/307 (39%), Gaps = 49/307 (15%) Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDV------------ELD 231 Q+ + + ED + +K+++E ++ +EAEEGE ED SS+V E + Sbjct: 1205 QESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETE 1264 Query: 232 TLS-QVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGG 290 T +VEEE R + + + + ++E AA + + + Sbjct: 1265 TKEPEVEEEE---EKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDD 1321 Query: 291 MKGILSNSWKRRYHSRRIQRDVI---------------KKRALIGD--DVGLTSYKHRHS 333 G L ++ K+ + + DV K R I D + L S + + S Sbjct: 1322 --GHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPS 1379 Query: 334 GLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSS 393 +V E + E++ EE+ +EE ++ ++ + H EL L+ + + + Sbjct: 1380 HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIP---HSELD-LETVQAVQSLTQEE 1435 Query: 394 ASSSDSDEMDYDLELKMIST--------PSPKKSMKMTMYADEVESQLKNIRN--SMRAD 443 +S + D + L T P+ SM +A E S + ++++ S Sbjct: 1436 SSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVR 1495 Query: 444 SVSSSNI 450 SVSS N+ Sbjct: 1496 SVSSPNV 1502 >gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 48.1 bits (113), Expect = 2e-05 Identities = 94/482 (19%), Positives = 196/482 (40%), Gaps = 88/482 (18%) Query: 172 TRALINMSSLPA--QDKIRSRDASEDKSAEKRKKDKQ-----EDSSDDDEAEEGEVEDEN 224 ++ ++ SLPA Q R R +++ ++R DK E++S + + GE +++ Sbjct: 847 SKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKS 906 Query: 225 SSDVELDTLSQVEEESLLRNDLRPAN-------------------------------KLA 253 + E T S EE L+ ++ +P+ +L Sbjct: 907 EATQEQYTES---EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLT 963 Query: 254 KGNRLFMRFATKDDKKEL-GAARRSQYYMKYGNPNYGGMKGILSNSWKRR----YHSRRI 308 +G+ R ++ D+ L G + S+ + +P + + KR+ + RR+ Sbjct: 964 EGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRV 1023 Query: 309 QRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEE-----EEEEEEEEEDQDM 363 ++ +++ + + T+ V +EP E+ + E E E +EE+++ Sbjct: 1024 RKRKHHNSSVVTETISETT---------EVLDEPFEDSDSERPMPRLEPTFEIDEEEEEE 1074 Query: 364 DADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPS--PKKSMK 421 D ++ EY L + R +S+S+R S + +E D + ++ S K+ +K Sbjct: 1075 DENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVK 1134 Query: 422 MTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRP 481 + + + LK + + S + K R G K P K + R ++ Q P Sbjct: 1135 NSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRK-PGFKLS--REIMPVSTQACVIEP 1191 Query: 482 PVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKK 541 VS K+ G++P E S V EP D+ L R++ + + A+ E + Sbjct: 1192 IVSIPKA------GRKPKIQE---SEETV---EPKEDM--PLPEERKEEEEMQAEAEEAE 1237 Query: 542 SGN----LWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSR 597 G + + +A N+ + + + P EE++ + + + +E+ QS +++ Sbjct: 1238 EGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPR-----VSEEQRQSEEEQQE 1292 Query: 598 LD 599 L+ Sbjct: 1293 LE 1294 Score = 39.7 bits (91), Expect = 0.008 Identities = 65/282 (23%), Positives = 97/282 (34%), Gaps = 60/282 (21%) Query: 338 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 397 +PEE EEEE + E EE EE E++D + E+PA S A SS Sbjct: 1219 LPEERKEEEEMQAEAEEAEEGEEEDAASS---------EVPAA-----------SPADSS 1258 Query: 398 DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNK 457 +S E + T P+ E E + + R ++ Sbjct: 1259 NSPETE---------TKEPEV---------EEEEEKPRVSEEQRQSEEEQQELEEP---- 1296 Query: 458 LPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSS 517 PE+ D + H +S ++ L ++P + V+ EP Sbjct: 1297 -EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRED--------VKEEP-- 1345 Query: 518 DVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSEL 577 GV +REK T L S + +T V + G+E+D E Sbjct: 1346 ------GVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEED 1399 Query: 578 QRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAE 619 LI+ KE+ S LD L ++Q S SE E Sbjct: 1400 SHTKEELIELKEEEEIPHSELD-LETVQAVQSLTQEESSEHE 1440 Score = 38.1 bits (87), Expect = 0.024 Identities = 65/307 (21%), Positives = 122/307 (39%), Gaps = 49/307 (15%) Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDV------------ELD 231 Q+ + + ED + +K+++E ++ +EAEEGE ED SS+V E + Sbjct: 1205 QESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETE 1264 Query: 232 TLS-QVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGG 290 T +VEEE R + + + + ++E AA + + + Sbjct: 1265 TKEPEVEEEE---EKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDD 1321 Query: 291 MKGILSNSWKRRYHSRRIQRDVI---------------KKRALIGD--DVGLTSYKHRHS 333 G L ++ K+ + + DV K R I D + L S + + S Sbjct: 1322 --GHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPS 1379 Query: 334 GLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSS 393 +V E + E++ EE+ +EE ++ ++ + H EL L+ + + + Sbjct: 1380 HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIP---HSELD-LETVQAVQSLTQEE 1435 Query: 394 ASSSDSDEMDYDLELKMIST--------PSPKKSMKMTMYADEVESQLKNIRN--SMRAD 443 +S + D + L T P+ SM +A E S + ++++ S Sbjct: 1436 SSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVR 1495 Query: 444 SVSSSNI 450 SVSS N+ Sbjct: 1496 SVSSPNV 1502 >gi|122937227 U2-associated SR140 protein [Homo sapiens] Length = 1029 Score = 48.1 bits (113), Expect = 2e-05 Identities = 55/239 (23%), Positives = 97/239 (40%), Gaps = 19/239 (7%) Query: 344 EEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMD 403 EE EEEE + +EEE ED++ D E+H +K+ S + S S + Sbjct: 786 EESEEEENQNQEEESEDEE-DTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKL 844 Query: 404 YDLELKMI-------STPSPKK-----SMKMTMYADEV--ESQLKNIRNSMRADSVSSSN 449 ++ELK++ S PKK ++ Y D++ + K + D Sbjct: 845 REIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEK 904 Query: 450 IKNRIGNKLPPEKFADVRHLLDEKRQHS-RPRPPVSSTKSDIRQRLGKRPHSPEKAFSSN 508 +++R +K ++ R + KR+HS P P SS+ ++ K S E++ S+ Sbjct: 905 LESRSKDKKEKDECTPTRK--ERKRRHSTSPSPSRSSSGRRVKSPSPKSERS-ERSERSH 961 Query: 509 PVVRREPSSDVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRA 567 R SS S V ++ + K+S +R K ++ + HR+ Sbjct: 962 KESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRS 1020 Score = 32.0 bits (71), Expect = 1.7 Identities = 52/263 (19%), Positives = 84/263 (31%), Gaps = 57/263 (21%) Query: 341 EPIEEEEEEEEEEEEEEEED----------------------------QDMDADDRV--- 369 E EEEE + +EEE E+EED +M + R Sbjct: 786 EESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLR 845 Query: 370 -----VVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTM 424 V+++ +EL + K+P++ S + + + E ++ K K Sbjct: 846 EIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDK--- 902 Query: 425 YADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVS 484 +++ES+ K+ + K R P + + R + + R Sbjct: 903 --EKLESRSKDKKEKDECTPTRKER-KRRHSTSPSPSRSSSGRRVKSPSPKSERSERSER 959 Query: 485 STKSDIRQRLGKR--PHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKKS 542 S K R R + P K +P R P SR P KKS Sbjct: 960 SHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSP-------------KKS 1006 Query: 543 GNLWTRLGSAPKTKEKNTKKVDH 565 G +P K +KK H Sbjct: 1007 GKKSRSQSRSPHRSHKKSKKNKH 1029 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 47.8 bits (112), Expect = 3e-05 Identities = 42/161 (26%), Positives = 70/161 (43%), Gaps = 20/161 (12%) Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRS------- 392 E+ ++E+E+E+++E+E E+D+ + D++ + P PR +ASRRS Sbjct: 442 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP----PRSYNASRRSRSSSRER 497 Query: 393 ----SASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSS 448 S SSS S ++ K +PSP+ K ++ + R R+ S+ S Sbjct: 498 RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 557 Query: 449 NIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSD 489 + +R G EK L EK + P VS D Sbjct: 558 S-NDRDGK----EKLEKNSTSLKEKEHNKEPDSSVSKEVDD 593 Score = 38.9 bits (89), Expect = 0.014 Identities = 55/244 (22%), Positives = 87/244 (35%), Gaps = 37/244 (15%) Query: 338 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 397 V E+ E+E E E+E E+E+E ++ D D ++ RE+ + Sbjct: 390 VKEKDREKEREREKEREKEKERGKNKDRDKE-----------REKDREKDKEKDRERERE 438 Query: 398 DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVS--SSNIKNRIG 455 E D D E + ++ + DE + K R R+ + S S + Sbjct: 439 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERR 498 Query: 456 NKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREP 515 + R KR+ SR P S K D ++R +R H E+ R+ Sbjct: 499 RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD-KKREKERDHISERRERERSTSMRKS 557 Query: 516 SSDVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDS 575 S+D +D K + EK S +L KEK K + E DD Sbjct: 558 SND---------RDGK----EKLEKNSTSL----------KEKEHNKEPDSSVSKEVDDK 594 Query: 576 ELQR 579 + R Sbjct: 595 DAPR 598 Score = 35.0 bits (79), Expect = 0.21 Identities = 43/194 (22%), Positives = 73/194 (37%), Gaps = 17/194 (8%) Query: 426 ADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSS 485 A E+E +K +R A S S+ I+ G + H + R S+ Sbjct: 272 AKELEEVMKRVRE---AQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKR 328 Query: 486 TKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKKSGNL 545 ++S R R R S +K + ++ S R R S+ DTREK Sbjct: 329 SQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK----- 383 Query: 546 WTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLDNLPSLQ 605 + + KEK+ +K R +E + E +R K++++ R+K D + Sbjct: 384 ---IKEKERVKEKDREKERERE---KEREKEKERGKN---KDRDKEREKDREKDKEKDRE 434 Query: 606 IEVSRESSSGSEAE 619 E +E + E Sbjct: 435 REREKEHEKDRDKE 448 Score = 33.9 bits (76), Expect = 0.46 Identities = 34/184 (18%), Positives = 73/184 (39%), Gaps = 6/184 (3%) Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLR 243 +DK R +D +DK ++ ++ ++E D D +E E E + + E D +++E+ Sbjct: 417 RDKEREKDREKDKEKDREREREKEHEKDRD--KEKEKEQDKEKEREKDRSKEIDEKRKKD 474 Query: 244 NDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRY 303 R + +R + + ++ ++ RS K + S ++ Sbjct: 475 KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSK--TIKRKSSRSPSPRSRNKKD 532 Query: 304 HSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEE--PIEEEEEEEEEEEEEEEEDQ 361 R +RD I +R + + G + + ++E+E +E + +E Sbjct: 533 KKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVD 592 Query: 362 DMDA 365 D DA Sbjct: 593 DKDA 596 Score = 30.8 bits (68), Expect = 3.9 Identities = 50/236 (21%), Positives = 88/236 (37%), Gaps = 27/236 (11%) Query: 186 KIRSRDASEDK--------------SAEKRKKDKQEDSSDDDEAEEGEVED---ENSSDV 228 K RSR S DK + R+K+++ + + E E G+ +D E D Sbjct: 366 KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR 425 Query: 229 ELDTLSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNY 288 E D E E ++ + +K + + + KD KE+ R+ + +Y Sbjct: 426 EKDKEKDREREREKEHE-KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY 484 Query: 289 GGMKGILSNS-WKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEE 347 + S+S +RR SR R + + S + R+ ++ E+E Sbjct: 485 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK------KDKKREKE 538 Query: 348 EEEEEEEEEEEEDQDM--DADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDE 401 + E E E M ++DR E E+ + +E + SS S D+ Sbjct: 539 RDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK 594 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 47.8 bits (112), Expect = 3e-05 Identities = 42/161 (26%), Positives = 70/161 (43%), Gaps = 20/161 (12%) Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRS------- 392 E+ ++E+E+E+++E+E E+D+ + D++ + P PR +ASRRS Sbjct: 326 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP----PRSYNASRRSRSSSRER 381 Query: 393 ----SASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSS 448 S SSS S ++ K +PSP+ K ++ + R R+ S+ S Sbjct: 382 RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 441 Query: 449 NIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSD 489 + +R G EK L EK + P VS D Sbjct: 442 S-NDRDGK----EKLEKNSTSLKEKEHNKEPDSSVSKEVDD 477 Score = 38.9 bits (89), Expect = 0.014 Identities = 55/244 (22%), Positives = 87/244 (35%), Gaps = 37/244 (15%) Query: 338 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 397 V E+ E+E E E+E E+E+E ++ D D ++ RE+ + Sbjct: 274 VKEKDREKEREREKEREKEKERGKNKDRDKE-----------REKDREKDKEKDRERERE 322 Query: 398 DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVS--SSNIKNRIG 455 E D D E + ++ + DE + K R R+ + S S + Sbjct: 323 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERR 382 Query: 456 NKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREP 515 + R KR+ SR P S K D ++R +R H E+ R+ Sbjct: 383 RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD-KKREKERDHISERRERERSTSMRKS 441 Query: 516 SSDVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDS 575 S+D +D K + EK S +L KEK K + E DD Sbjct: 442 SND---------RDGK----EKLEKNSTSL----------KEKEHNKEPDSSVSKEVDDK 478 Query: 576 ELQR 579 + R Sbjct: 479 DAPR 482 Score = 35.0 bits (79), Expect = 0.21 Identities = 43/194 (22%), Positives = 73/194 (37%), Gaps = 17/194 (8%) Query: 426 ADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSS 485 A E+E +K +R A S S+ I+ G + H + R S+ Sbjct: 156 AKELEEVMKRVRE---AQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKR 212 Query: 486 TKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKKSGNL 545 ++S R R R S +K + ++ S R R S+ DTREK Sbjct: 213 SQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK----- 267 Query: 546 WTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLDNLPSLQ 605 + + KEK+ +K R +E + E +R K++++ R+K D + Sbjct: 268 ---IKEKERVKEKDREKERERE---KEREKEKERGKN---KDRDKEREKDREKDKEKDRE 318 Query: 606 IEVSRESSSGSEAE 619 E +E + E Sbjct: 319 REREKEHEKDRDKE 332 Score = 33.9 bits (76), Expect = 0.46 Identities = 34/184 (18%), Positives = 73/184 (39%), Gaps = 6/184 (3%) Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLR 243 +DK R +D +DK ++ ++ ++E D D +E E E + + E D +++E+ Sbjct: 301 RDKEREKDREKDKEKDREREREKEHEKDRD--KEKEKEQDKEKEREKDRSKEIDEKRKKD 358 Query: 244 NDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRY 303 R + +R + + ++ ++ RS K + S ++ Sbjct: 359 KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSK--TIKRKSSRSPSPRSRNKKD 416 Query: 304 HSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEE--PIEEEEEEEEEEEEEEEEDQ 361 R +RD I +R + + G + + ++E+E +E + +E Sbjct: 417 KKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVD 476 Query: 362 DMDA 365 D DA Sbjct: 477 DKDA 480 Score = 30.8 bits (68), Expect = 3.9 Identities = 50/236 (21%), Positives = 88/236 (37%), Gaps = 27/236 (11%) Query: 186 KIRSRDASEDK--------------SAEKRKKDKQEDSSDDDEAEEGEVED---ENSSDV 228 K RSR S DK + R+K+++ + + E E G+ +D E D Sbjct: 250 KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR 309 Query: 229 ELDTLSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNY 288 E D E E ++ + +K + + + KD KE+ R+ + +Y Sbjct: 310 EKDKEKDREREREKEHE-KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY 368 Query: 289 GGMKGILSNS-WKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEE 347 + S+S +RR SR R + + S + R+ ++ E+E Sbjct: 369 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK------KDKKREKE 422 Query: 348 EEEEEEEEEEEEDQDM--DADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDE 401 + E E E M ++DR E E+ + +E + SS S D+ Sbjct: 423 RDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK 478 >gi|5803109 osteosarcoma amplified 9 isoform 1 precursor [Homo sapiens] Length = 667 Score = 47.0 bits (110), Expect = 5e-05 Identities = 59/252 (23%), Positives = 100/252 (39%), Gaps = 34/252 (13%) Query: 344 EEEEEEEEEEEEEEEEDQDMDADDRVVV-EYHEELPALKQPRERSASRRSSASSSDSD-- 400 + E + E EEEE+E+ED+D D D+R ++ E+ +EL + P +R R + + + Sbjct: 406 DPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSEVKAGMERELE 465 Query: 401 ----EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGN 456 E + +L+ + S ++ M + +K + + V K + Sbjct: 466 NIIQETEKELDPDGLKKES-ERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPK 524 Query: 457 KLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGK-RPHSPEKAFSSNPVVRREP 515 K PP P+P + +R R+ K R P + + + R P Sbjct: 525 KPPPS-----------------PQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENP 567 Query: 516 SSDVHSRLGVPRQDSKGLYADTR-EKKSGNLW---TRLGSAPKTKE--KNTKKV--DHRA 567 L + +GL A + E K W T G+ T E +N K++ + Sbjct: 568 QLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILV 627 Query: 568 PGAEEDDSELQR 579 PGAEE E QR Sbjct: 628 PGAEEAQKERQR 639 >gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sapiens] Length = 528 Score = 47.0 bits (110), Expect = 5e-05 Identities = 38/118 (32%), Positives = 55/118 (46%), Gaps = 23/118 (19%) Query: 325 LTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPR 384 LT K + + P E EEEEEEEEEE EEEEE++D + E P L P+ Sbjct: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSE----------EAPPPLSPPQ 346 Query: 385 ERSASRRSSASSSDSDEM-DYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMR 441 AS ++ D+M YD + + + + K +E E LK++ S+R Sbjct: 347 --------PASPAEEDKMPPYDEQTQAFIDAAQEARNKF----EEAERSLKDMEESIR 392 >gi|13376339 plasticity-related protein 2 [Homo sapiens] Length = 746 Score = 47.0 bits (110), Expect = 5e-05 Identities = 24/51 (47%), Positives = 34/51 (66%), Gaps = 2/51 (3%) Query: 314 KKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMD 364 K+++L G +GL G + P EP+ EEEEEEE+EEEEEEE+++ D Sbjct: 440 KQKSLEGRGLGLPD--DASPGHLRAPAEPMAEEEEEEEDEEEEEEEEEEED 488 >gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] Length = 727 Score = 47.0 bits (110), Expect = 5e-05 Identities = 41/129 (31%), Positives = 62/129 (48%), Gaps = 21/129 (16%) Query: 338 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 397 V E+ EEEEEEEEEEEEEEEE+++ + D+R + EE RS AS S Sbjct: 225 VDEDGEEEEEEEEEEEEEEEEEEEEYEQDER---DQKEE--------GNDYDTRSEASDS 273 Query: 398 DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIR--NSMRADSVSSSNIKNRIG 455 S+ + + T +S T +DE + + K R + + D SS ++ G Sbjct: 274 GSESVSF--------TDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAG 325 Query: 456 NKLPPEKFA 464 ++ EK + Sbjct: 326 SEKKHEKLS 334 Score = 43.1 bits (100), Expect = 8e-04 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 4/84 (4%) Query: 340 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDS 399 EE +EE+ EE+EE EE+ EED+++D D E EE ++ E D Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEE----EEEEEEEEEEEYEQDERDQ 257 Query: 400 DEMDYDLELKMISTPSPKKSMKMT 423 E D + + ++ S +S+ T Sbjct: 258 KEEGNDYDTRSEASDSGSESVSFT 281 Score = 32.3 bits (72), Expect = 1.3 Identities = 15/49 (30%), Positives = 25/49 (51%) Query: 191 DASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239 D ED+ E+ ++ +E D +E EE E E+E + E + Q E + Sbjct: 208 DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERD 256 Score = 29.6 bits (65), Expect = 8.6 Identities = 16/69 (23%), Positives = 33/69 (47%), Gaps = 8/69 (11%) Query: 179 SSLPAQDKIRSRDASEDKSA--------EKRKKDKQEDSSDDDEAEEGEVEDENSSDVEL 230 SS +++++ S + D + + +E+ ++D E+ EVE++ D E+ Sbjct: 166 SSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEV 225 Query: 231 DTLSQVEEE 239 D + EEE Sbjct: 226 DEDGEEEEE 234 >gi|58761548 tau tubulin kinase 1 [Homo sapiens] Length = 1321 Score = 46.6 bits (109), Expect = 7e-05 Identities = 55/199 (27%), Positives = 83/199 (41%), Gaps = 14/199 (7%) Query: 288 YGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEE 347 Y K LS+ +R R++R L V L + + +G EE +EEE Sbjct: 685 YQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEE 744 Query: 348 EEE----EEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMD 403 EEE EEEEEEEEE+++ + ++ L + PR S+S S S+ S E Sbjct: 745 EEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQEG- 803 Query: 404 YDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNI-KNRIGNKLPPEK 462 + K+S AD L+ S VS ++ K+ + +L P+ Sbjct: 804 ---APSTLLADDQKESRGRASMAD---GDLEPEEGSKTLVLVSPGDMKKSPVTAELAPD- 856 Query: 463 FADVRHLLDEKRQHSRPRP 481 D+ L QH RP+P Sbjct: 857 -PDLGTLAALTPQHERPQP 874 Score = 33.1 bits (74), Expect = 0.78 Identities = 11/48 (22%), Positives = 28/48 (58%) Query: 182 PAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVE 229 P Q + ++ E++ ++ ++++ E+ +++E EE E E+E + E Sbjct: 724 PVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771 Score = 32.0 bits (71), Expect = 1.7 Identities = 13/38 (34%), Positives = 24/38 (63%) Query: 202 KKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239 K++++E+ D++E EE E E+E + E + + EEE Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEE 769 Score = 31.2 bits (69), Expect = 3.0 Identities = 12/44 (27%), Positives = 25/44 (56%) Query: 183 AQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSS 226 A K + ED+ E+ ++++E+ +++E EE E E+E + Sbjct: 729 ANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEA 772 Score = 29.6 bits (65), Expect = 8.6 Identities = 11/41 (26%), Positives = 26/41 (63%) Query: 200 KRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEES 240 K +++++E+ +++E +E E E+E + E + + EEE+ Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEA 772 >gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8 [Homo sapiens] Length = 780 Score = 46.6 bits (109), Expect = 7e-05 Identities = 55/255 (21%), Positives = 106/255 (41%), Gaps = 30/255 (11%) Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDE---------AEEGEVEDENSSDVEL--DT 232 ++K +R +++ E+RK+ ++E E A E + + V L D Sbjct: 106 KEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDR 165 Query: 233 LSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMK 292 L Q+E + +R K + + R A ++ +KE A R + + +Y Sbjct: 166 LEQLERKRERERKMREQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDK- 223 Query: 293 GILSNSWKR--------RYH----SRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPE 340 + ++ W R R+ + ++ + +++R L+ D ++ + + S + Sbjct: 224 -VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSA 282 Query: 341 EPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPAL----KQPRERSASRRSSASS 396 E EEEEEEEEEEEEE + + E EE ++ E+SA S Sbjct: 283 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 342 Query: 397 SDSDEMDYDLELKMI 411 S+ +E + + L ++ Sbjct: 343 SEDEERENENHLLVV 357 Score = 37.4 bits (85), Expect = 0.041 Identities = 69/306 (22%), Positives = 133/306 (43%), Gaps = 56/306 (18%) Query: 184 QDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVED-------ENSSDVELDTLSQ- 235 Q+K R ++ E+K+ KR K+ + S D EEGE+ D NS D++ Sbjct: 18 QEKKRRKE-QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76 Query: 236 -VEEESLLRNDLRPANKLAKGNRLFMRFATKDDK-KELGAARRSQYYMKY-GNPNYGGMK 292 E++SL ++P ++++ ++ R KD+K KE AR + ++ + + Sbjct: 77 GEEDDSLA---IKPPQQMSRKEKVHHR---KDEKRKEKKHARVKEKEREHERRKRHREEQ 130 Query: 293 GILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEE 352 W+R+ + ++R G+D G+ ++ R L + + E + E++ Sbjct: 131 DKARREWERQKRREMAREHSRRER---GND-GVCLFRDR---LEQLERKRERERKMREQQ 183 Query: 353 EEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMI- 411 +E+ E+++++ A++R +ER A R SA E DY ++K Sbjct: 184 KEQREQKERERRAEER--------------RKEREARREVSAHHRTMRE-DYSDKVKASH 228 Query: 412 ---STPSP-----------KKSMKMTMYADEVESQLKNIRNSMR-ADSVSSSNIKNRIGN 456 S P P K + M ++ S L++I +S R S SS+ ++ G+ Sbjct: 229 WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS 288 Query: 457 KLPPEK 462 + E+ Sbjct: 289 EEEEEE 294 >gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] Length = 587 Score = 46.6 bits (109), Expect = 7e-05 Identities = 26/82 (31%), Positives = 46/82 (56%), Gaps = 4/82 (4%) Query: 335 LVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSA 394 L ++ ++ EEEEEE EEEEEE EE+++ D ++ E EE ++P++R +S+ Sbjct: 354 LASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEE----EEPQQRGQGEKSAT 409 Query: 395 SSSDSDEMDYDLELKMISTPSP 416 S + + ++S+P P Sbjct: 410 PSRKILDPNTGEPAPVLSSPPP 431 Score = 30.8 bits (68), Expect = 3.9 Identities = 11/33 (33%), Positives = 22/33 (66%) Query: 191 DASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDE 223 D E++ E+ +++ +E+ +D+E EE E E+E Sbjct: 362 DEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEE 394 Score = 30.4 bits (67), Expect = 5.1 Identities = 13/32 (40%), Positives = 20/32 (62%) Query: 208 DSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239 D D++E EEGE E+E + + E + + EEE Sbjct: 359 DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEE 390 Score = 29.6 bits (65), Expect = 8.6 Identities = 11/43 (25%), Positives = 26/43 (60%) Query: 187 IRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVE 229 + S ED+ E+ ++++E++ +++E +E E E+E + E Sbjct: 354 LASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEE 396 Score = 29.6 bits (65), Expect = 8.6 Identities = 13/36 (36%), Positives = 20/36 (55%) Query: 204 DKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEE 239 D+ E+ ++ E EE E E+E D E + + EEE Sbjct: 360 DEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEE 395 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.308 0.126 0.345 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,114,530 Number of Sequences: 37866 Number of extensions: 1329315 Number of successful extensions: 38179 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 628 Number of HSP's successfully gapped in prelim test: 510 Number of HSP's that attempted gapping in prelim test: 14908 Number of HSP's gapped (non-prelim): 11242 length of query: 620 length of database: 18,247,518 effective HSP length: 108 effective length of query: 512 effective length of database: 14,157,990 effective search space: 7248890880 effective search space used: 7248890880 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.