BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|16507955 caspase recruitment domain protein 14 isoform 2 [Homo sapiens] (434 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|16507955 caspase recruitment domain protein 14 isoform 2 [Hom... 845 0.0 gi|13129124 caspase recruitment domain protein 14 isoform 1 [Hom... 740 0.0 gi|157743265 caspase recruitment domain family, member 11 [Homo ... 133 4e-31 gi|51093861 caspase recruitment domain protein 10 [Homo sapiens] 100 4e-21 gi|16554562 caspase recruitment domain protein 9 isoform 2 [Homo... 79 1e-14 gi|47717131 caspase recruitment domain protein 9 isoform 1 [Homo... 79 1e-14 gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 57 4e-08 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 56 6e-08 gi|31982906 cingulin-like 1 [Homo sapiens] 55 1e-07 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 54 2e-07 gi|46852390 coiled-coil domain containing 6 [Homo sapiens] 54 2e-07 gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 54 3e-07 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 52 1e-06 gi|21735548 centrosomal protein 2 [Homo sapiens] 51 2e-06 gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 51 2e-06 gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 51 2e-06 gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens] 51 2e-06 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 3e-06 gi|4506467 radixin [Homo sapiens] 50 3e-06 gi|219521893 coiled-coil transcriptional coactivator isoform 2 [... 50 3e-06 gi|148746195 trichohyalin [Homo sapiens] 50 5e-06 gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 50 5e-06 gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 49 7e-06 gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 49 7e-06 gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 49 7e-06 gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 49 7e-06 gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 49 9e-06 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 49 1e-05 gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 49 1e-05 gi|78042577 MAP7 domain containing 1 [Homo sapiens] 49 1e-05 >gi|16507955 caspase recruitment domain protein 14 isoform 2 [Homo sapiens] Length = 434 Score = 845 bits (2183), Expect = 0.0 Identities = 434/434 (100%), Positives = 434/434 (100%) Query: 1 MVSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGS 60 MVSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGS Sbjct: 1 MVSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGS 60 Query: 61 RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL 120 RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL Sbjct: 61 RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL 120 Query: 121 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 180 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE Sbjct: 121 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 180 Query: 181 ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPA 240 ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPA Sbjct: 181 ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPA 240 Query: 241 PPSQQSLYKRVAEDFGEEPWSFSSCLEIPEGDPGALPGAKAGDPHLDYELLDTADLPQLE 300 PPSQQSLYKRVAEDFGEEPWSFSSCLEIPEGDPGALPGAKAGDPHLDYELLDTADLPQLE Sbjct: 241 PPSQQSLYKRVAEDFGEEPWSFSSCLEIPEGDPGALPGAKAGDPHLDYELLDTADLPQLE 300 Query: 301 SSLQPVSPGRLDVSESGVLMRRRPARRILSQVTMLAFQGDALLEQISVIGGNLTGIFIHR 360 SSLQPVSPGRLDVSESGVLMRRRPARRILSQVTMLAFQGDALLEQISVIGGNLTGIFIHR Sbjct: 301 SSLQPVSPGRLDVSESGVLMRRRPARRILSQVTMLAFQGDALLEQISVIGGNLTGIFIHR 360 Query: 361 VTPGSAADQMALRPGTQIVMVSRARPLLSPGLLMGTVAAGGVTQADFTSPRRCRSTLGWA 420 VTPGSAADQMALRPGTQIVMVSRARPLLSPGLLMGTVAAGGVTQADFTSPRRCRSTLGWA Sbjct: 361 VTPGSAADQMALRPGTQIVMVSRARPLLSPGLLMGTVAAGGVTQADFTSPRRCRSTLGWA 420 Query: 421 SALSWADVKRSAHL 434 SALSWADVKRSAHL Sbjct: 421 SALSWADVKRSAHL 434 >gi|13129124 caspase recruitment domain protein 14 isoform 1 [Homo sapiens] Length = 1004 Score = 740 bits (1910), Expect = 0.0 Identities = 381/381 (100%), Positives = 381/381 (100%) Query: 1 MVSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGS 60 MVSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGS Sbjct: 238 MVSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGS 297 Query: 61 RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL 120 RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL Sbjct: 298 RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL 357 Query: 121 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 180 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE Sbjct: 358 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 417 Query: 181 ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPA 240 ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPA Sbjct: 418 ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPA 477 Query: 241 PPSQQSLYKRVAEDFGEEPWSFSSCLEIPEGDPGALPGAKAGDPHLDYELLDTADLPQLE 300 PPSQQSLYKRVAEDFGEEPWSFSSCLEIPEGDPGALPGAKAGDPHLDYELLDTADLPQLE Sbjct: 478 PPSQQSLYKRVAEDFGEEPWSFSSCLEIPEGDPGALPGAKAGDPHLDYELLDTADLPQLE 537 Query: 301 SSLQPVSPGRLDVSESGVLMRRRPARRILSQVTMLAFQGDALLEQISVIGGNLTGIFIHR 360 SSLQPVSPGRLDVSESGVLMRRRPARRILSQVTMLAFQGDALLEQISVIGGNLTGIFIHR Sbjct: 538 SSLQPVSPGRLDVSESGVLMRRRPARRILSQVTMLAFQGDALLEQISVIGGNLTGIFIHR 597 Query: 361 VTPGSAADQMALRPGTQIVMV 381 VTPGSAADQMALRPGTQIVMV Sbjct: 598 VTPGSAADQMALRPGTQIVMV 618 >gi|157743265 caspase recruitment domain family, member 11 [Homo sapiens] Length = 1154 Score = 133 bits (334), Expect = 4e-31 Identities = 124/484 (25%), Positives = 202/484 (41%), Gaps = 110/484 (22%) Query: 1 MVSSCELELQEQSLRTASDQESGD--EELNRLKEENEKLRSLTFSL-------------- 44 M C+LE + QSL+ +D E+ E++ L+ ENE L++ L Sbjct: 239 MEEECKLE-RNQSLKLKNDIENRPKKEQVLELERENEMLKTKNQELQSIIQAGKRSLPDS 297 Query: 45 --AEKDILEQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMA 102 A DILE EA RQELV RI++L+E A AE R++Y EEKE L+ Sbjct: 298 DKAILDILEHDRKEALEDRQELVNRIYNLQEEARQAEELRDKYLEEKEDLELKCSTLGKD 357 Query: 103 CQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQ---- 158 C++Y+ ++N + Q+ E+++ERDQA+ +RD AQ + SQ L+EKD R+Q+ EL ++ Sbjct: 358 CEMYKHRMNTVMLQLEEVERERDQAFHSRDEAQTQYSQCLIEKDKYRKQIRELEEKNDEM 417 Query: 159 ----------VCELRTQLRQLQAE------------PPGVLKQ---------------EA 181 + L ++LR+L + P ++ Q ++ Sbjct: 418 RIEMVRREACIVNLESKLRRLSKDSNNLDQSLPRNLPVTIISQDFGDASPRTNGQEADDS 477 Query: 182 RTREPCPREKQRLVRMH------------------AICPRDDSDCSLVSSTESQLLSDLS 223 T E P + + + H I + SD E + S Sbjct: 478 STSEESPEDSKYFLPYHPPQRRMNLKGIQLQRAKSPISLKRTSDFQAKGHEEEGTDASPS 537 Query: 224 ATSSRELVDSFRSSSP------------APPSQQSLYKRVAEDFGEEPWSFSSCLEIPEG 271 + S + +SF P PP S+ +R ED S +E + Sbjct: 538 SCGSLPITNSFTKMQPPRSRSSIMSITAEPPGNDSIVRRYKEDAPHR-----STVE-EDN 591 Query: 272 DPGALPGAKAGDPHLDYELLDTADLPQLESSLQPVSPGRLDVSESGVLMRR----RPARR 327 D G D + + + SS Q D+ + ++ R+ RP R Sbjct: 592 DSGGFDALDLDDDSHERYSFGPSSIHSSSSSHQSEGLDAYDLEQVNLMFRKFSLERPFRP 651 Query: 328 ILSQVTML----------AFQGDALLEQISVIGGNLTGIFIHRVTPGSAADQMALRPGTQ 377 ++ V + GD+L Q++++GGN G F+H V PGS A++ LR G Q Sbjct: 652 SVTSVGHVRGPGPSVQHTTLNGDSLTSQLTLLGGNARGSFVHSVKPGSLAEKAGLREGHQ 711 Query: 378 IVMV 381 ++++ Sbjct: 712 LLLL 715 Score = 31.2 bits (69), Expect = 1.9 Identities = 39/198 (19%), Positives = 88/198 (44%), Gaps = 16/198 (8%) Query: 7 LELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVE 66 L QE+ + +++S ++EL ++K++N L L+E+ ++ +R + E+ + Sbjct: 174 LTFQERYYKMKEERDSYNDELVKVKDDNYNLAMRYAQLSEEK--NMAVMRSRDLQLEIDQ 231 Query: 67 RIHSLRERAVAAERQREQYWE---------EKEQTLLQFQKSKMACQLYREKVNALQAQV 117 H L + + +R Q + +KEQ L ++++M +E + +QA Sbjct: 232 LKHRLNKMEEECKLERNQSLKLKNDIENRPKKEQVLELERENEMLKTKNQELQSIIQAGK 291 Query: 118 CELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVL 177 L D + D + + ++L ++ L +++ L ++ + +LR E L Sbjct: 292 RSLP---DSDKAILDILEHDRKEALEDRQELVNRIYNLQEEARQAE-ELRDKYLEEKEDL 347 Query: 178 KQEART-REPCPREKQRL 194 + + T + C K R+ Sbjct: 348 ELKCSTLGKDCEMYKHRM 365 >gi|51093861 caspase recruitment domain protein 10 [Homo sapiens] Length = 1032 Score = 99.8 bits (247), Expect = 4e-21 Identities = 78/237 (32%), Positives = 117/237 (49%), Gaps = 18/237 (7%) Query: 48 DILEQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYR 107 DILE EA+ SRQEL +++H+++ AE R+QY +E E L+ + + C LY+ Sbjct: 319 DILEHDWREAQDSRQELCQKLHAVQGELQWAEELRDQYLQEMEDLRLKHRTLQKDCDLYK 378 Query: 108 EKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLR 167 ++ + AQ+ E++KERDQA +RD Q + SQSL+EKD R+QV L + EL T L Sbjct: 379 HRMATVLAQLEEIEKERDQAIQSRDRIQLQYSQSLIEKDQYRKQVRGLEAERDELLTTLT 438 Query: 168 QLQAEPPGVLKQEARTREPCPREKQRLVRMHAICPRDDSDCSL----------VSSTESQ 217 L E L + R + H++C S SL ++ E+ Sbjct: 439 SL--EGTKALLEVQLQRAQGGTCLKACASSHSLCSNLSSTWSLSEFPSPLGGPEATGEAA 496 Query: 218 LLSDLSATSSRELVDSFR-----SSSPAPPSQQSLYKRVAEDFGEEP-WSFSSCLEI 268 ++ +S E DS + S P PPS S+ +R E+ P SFSS +I Sbjct: 497 VMGGPEPHNSEEATDSEKEINRLSILPFPPSAGSILRRQREEDPAPPKRSFSSMSDI 553 >gi|16554562 caspase recruitment domain protein 9 isoform 2 [Homo sapiens] Length = 492 Score = 78.6 bits (192), Expect = 1e-14 Identities = 68/234 (29%), Positives = 111/234 (47%), Gaps = 23/234 (9%) Query: 5 CELELQEQ-SLRTASDQESGDEELNRLKEENEKLRSLTFSLAEK-------------DIL 50 C++E + LR A +Q E L L++E L++ L +L Sbjct: 224 CKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVL 283 Query: 51 EQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKV 110 E+ +A QE I SLR+ E +R + EEKE LQ + ++Y++++ Sbjct: 284 EEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRI 343 Query: 111 NALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ 170 A+ Q+ E+ ERDQA + R+ + ++ L EKD+LR+QV EL ++ EL+ Q+ Q + Sbjct: 344 EAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCE 403 Query: 171 AEPPGVLKQEARTREPCPREKQRLVRMHAI---CPRDDSDCSLVSSTESQLLSD 221 A+ +L E R R ++ + LV + PR + SL E LSD Sbjct: 404 AQ---LLAVEGRLRR---QQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSD 451 Score = 38.9 bits (89), Expect = 0.009 Identities = 37/133 (27%), Positives = 62/133 (46%), Gaps = 15/133 (11%) Query: 10 QEQSLRTASDQESGDEELNRLKEENEKL-RSLTFSLAEKDI-------LEQSLDEARGSR 61 QE+ R + E+G EL R KEEN L L EK L+ +D+ + S Sbjct: 158 QERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSL 217 Query: 62 QEL-----VERIHSLRERAVAAER-QREQYWE-EKEQTLLQFQKSKMACQLYREKVNALQ 114 + VER H+L+ R +R +E WE ++E+ LLQ + ++ + K++ Sbjct: 218 MKAEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSS 277 Query: 115 AQVCELQKERDQA 127 + L+++ QA Sbjct: 278 PYIQVLEEDWRQA 290 Score = 29.6 bits (65), Expect = 5.6 Identities = 35/160 (21%), Positives = 72/160 (45%), Gaps = 14/160 (8%) Query: 21 ESGDEEL--NRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAA 78 ESG +L + + +K++ LT L+ KD + L ++ ER+ L+E A Sbjct: 112 ESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAG 171 Query: 79 ERQREQYWEEKEQTLLQF--QKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQR 136 R+ ++ EE ++ Q + L R + LQ ++ +L + A D + Sbjct: 172 SRELKRCKEENYDLAMRLAHQSEEKGAALMRNR--DLQLEIDQL---KHSLMKAEDDCKV 226 Query: 137 EISQSL-----VEKDSLRRQVFELTDQVCELRTQLRQLQA 171 E +L +E+ + ++EL + L+ ++++L+A Sbjct: 227 ERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEA 266 >gi|47717131 caspase recruitment domain protein 9 isoform 1 [Homo sapiens] Length = 536 Score = 78.6 bits (192), Expect = 1e-14 Identities = 68/234 (29%), Positives = 111/234 (47%), Gaps = 23/234 (9%) Query: 5 CELELQEQ-SLRTASDQESGDEELNRLKEENEKLRSLTFSLAEK-------------DIL 50 C++E + LR A +Q E L L++E L++ L +L Sbjct: 224 CKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVL 283 Query: 51 EQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKV 110 E+ +A QE I SLR+ E +R + EEKE LQ + ++Y++++ Sbjct: 284 EEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRI 343 Query: 111 NALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ 170 A+ Q+ E+ ERDQA + R+ + ++ L EKD+LR+QV EL ++ EL+ Q+ Q + Sbjct: 344 EAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCE 403 Query: 171 AEPPGVLKQEARTREPCPREKQRLVRMHAI---CPRDDSDCSLVSSTESQLLSD 221 A+ +L E R R ++ + LV + PR + SL E LSD Sbjct: 404 AQ---LLAVEGRLRR---QQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSD 451 Score = 38.9 bits (89), Expect = 0.009 Identities = 37/133 (27%), Positives = 62/133 (46%), Gaps = 15/133 (11%) Query: 10 QEQSLRTASDQESGDEELNRLKEENEKL-RSLTFSLAEKDI-------LEQSLDEARGSR 61 QE+ R + E+G EL R KEEN L L EK L+ +D+ + S Sbjct: 158 QERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSL 217 Query: 62 QEL-----VERIHSLRERAVAAER-QREQYWE-EKEQTLLQFQKSKMACQLYREKVNALQ 114 + VER H+L+ R +R +E WE ++E+ LLQ + ++ + K++ Sbjct: 218 MKAEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSS 277 Query: 115 AQVCELQKERDQA 127 + L+++ QA Sbjct: 278 PYIQVLEEDWRQA 290 Score = 29.6 bits (65), Expect = 5.6 Identities = 35/160 (21%), Positives = 72/160 (45%), Gaps = 14/160 (8%) Query: 21 ESGDEEL--NRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAA 78 ESG +L + + +K++ LT L+ KD + L ++ ER+ L+E A Sbjct: 112 ESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAG 171 Query: 79 ERQREQYWEEKEQTLLQF--QKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQR 136 R+ ++ EE ++ Q + L R + LQ ++ +L + A D + Sbjct: 172 SRELKRCKEENYDLAMRLAHQSEEKGAALMRNR--DLQLEIDQL---KHSLMKAEDDCKV 226 Query: 137 EISQSL-----VEKDSLRRQVFELTDQVCELRTQLRQLQA 171 E +L +E+ + ++EL + L+ ++++L+A Sbjct: 227 ERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEA 266 >gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 436 Score = 56.6 bits (135), Expect = 4e-08 Identities = 39/180 (21%), Positives = 86/180 (47%), Gaps = 2/180 (1%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 ++ QE+ +R +Q EE LK++ + + E+ + EQ ++ R +++ Sbjct: 256 QMRKQEEQMREQEEQMREQEE-QMLKQKEQTEQEEQTGEQEEQMREQE-EQMREQEEQMR 313 Query: 66 ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125 E+ +RE+ +Q EQ WE+KEQ Q ++ + E+ +Q Q +++K+ + Sbjct: 314 EQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEE 373 Query: 126 QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185 Q + +++ Q +++ + Q ++ +Q ++R Q Q+ + + KQE E Sbjct: 374 QMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGE 433 Score = 52.8 bits (125), Expect = 6e-07 Identities = 37/181 (20%), Positives = 88/181 (48%), Gaps = 2/181 (1%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDE-ARGSRQEL 64 E ++ EQ + +E ++ ++ E+ E++R + E++ Q +E + +++ Sbjct: 198 EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQM 257 Query: 65 VERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKER 124 ++ +RE+ Q EQ ++KEQT + Q + Q+ RE+ ++ Q +++++ Sbjct: 258 RKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQM-REQEEQMREQEEQMREQE 316 Query: 125 DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTR 184 +Q + ++ Q +K+ + Q ++ Q ++ Q Q+Q + V KQE + R Sbjct: 317 EQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMR 376 Query: 185 E 185 + Sbjct: 377 K 377 Score = 52.8 bits (125), Expect = 6e-07 Identities = 45/196 (22%), Positives = 95/196 (48%), Gaps = 8/196 (4%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQE-- 63 E ++ EQ + +E ++ +++++ E++R + E++ EQ L + + QE Sbjct: 233 EEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQE--EQMLKQKEQTEQEEQ 290 Query: 64 LVERIHSLRERAVAAERQREQYWEEKEQTLLQ-FQKSKMACQLYREKVNALQAQVCELQK 122 E+ +RE+ Q EQ E++EQ Q Q K Q++ +K + Q ++ K Sbjct: 291 TGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQK-EQMWEQKEQMWK 349 Query: 123 ERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQL--QAEPPGVLKQE 180 + +Q + Q++ Q +++ +R+Q ++ Q ++R Q Q+ Q E G K++ Sbjct: 350 QEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQ 409 Query: 181 ARTREPCPREKQRLVR 196 R +E E++ +R Sbjct: 410 MREQEEQMGEQKEQMR 425 Score = 50.8 bits (120), Expect = 2e-06 Identities = 36/183 (19%), Positives = 91/183 (49%), Gaps = 6/183 (3%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 +++ QE+ +R +Q EE +++E+ E++ +++ + ++ R +++ Sbjct: 249 QVQKQEEQMRKQEEQMREQEE--QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306 Query: 66 ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125 E+ +RE+ Q EQ +++EQ Q ++ + ++ + Q ++QK+ + Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEE 366 Query: 126 QAYSARDSAQREISQSLVEKDSLRR---QVFELTDQVCELRTQLRQLQAEPPGVLKQEAR 182 Q + +++ Q +++ +R+ Q+ E +Q+ E + Q+R+ Q E G K++ R Sbjct: 367 QVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMRE-QEEQMGEQKEQMR 425 Query: 183 TRE 185 +E Sbjct: 426 KQE 428 Score = 48.1 bits (113), Expect = 2e-05 Identities = 34/176 (19%), Positives = 86/176 (48%), Gaps = 2/176 (1%) Query: 10 QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIH 69 QE+ +R +Q EE + +EE + + E+ + EQ ++ R ++++++ Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQE-EQMREQEEQMLKQKE 283 Query: 70 SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYS 129 + E Q EQ E++EQ Q ++ + + RE+ + Q ++ ++++Q + Sbjct: 284 QTEQEEQTGE-QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342 Query: 130 ARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185 ++ ++ Q +++ +++Q ++ Q ++R Q Q++ + + KQE + E Sbjct: 343 QKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE 398 Score = 47.8 bits (112), Expect = 2e-05 Identities = 36/182 (19%), Positives = 86/182 (47%), Gaps = 7/182 (3%) Query: 10 QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIH 69 QE+ ++ +Q EE R +EE + E+ + +Q ++ R +++ E+ Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQE-EQMRKQEEQMREQEE 269 Query: 70 SLRERAVAAERQREQY------WEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE 123 +RE+ +Q+EQ E++EQ Q ++ + + RE+ ++ Q ++ K+ Sbjct: 270 QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ 329 Query: 124 RDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEART 183 +Q + ++ + Q +++ + Q ++ Q ++R Q Q++ + + KQE + Sbjct: 330 EEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQM 389 Query: 184 RE 185 R+ Sbjct: 390 RK 391 Score = 43.1 bits (100), Expect = 5e-04 Identities = 37/194 (19%), Positives = 92/194 (47%), Gaps = 4/194 (2%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKD--ILEQSLDEARGSRQE 63 E +++EQ + + E+ +++E+ ++R + E++ + EQ + R + Sbjct: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE-GQVREQEGQ 179 Query: 64 LVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE 123 + E+ +RE+ Q Q E++EQ Q ++ + + E+ ++ Q ++ ++ Sbjct: 180 VREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQ 239 Query: 124 RDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQL-QAEPPGVLKQEAR 182 +Q + Q++ Q +++ +R Q ++ +Q ++ Q Q Q E G +++ R Sbjct: 240 EEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMR 299 Query: 183 TREPCPREKQRLVR 196 +E RE++ +R Sbjct: 300 EQEEQMREQEEQMR 313 Score = 41.2 bits (95), Expect = 0.002 Identities = 35/182 (19%), Positives = 86/182 (47%), Gaps = 3/182 (1%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKD--ILEQSLDEARGSRQE 63 E +++EQ + + E+ +++E+ ++R + E++ + EQ + R + Sbjct: 86 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE-GQVREQEGQ 144 Query: 64 LVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE 123 + E+ +RE+ Q Q E++ Q Q + + RE+ + Q ++ ++ Sbjct: 145 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQ 204 Query: 124 RDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEART 183 +Q + Q++ Q +++ +R+Q ++ +Q +++ Q Q+Q + + KQE + Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264 Query: 184 RE 185 RE Sbjct: 265 RE 266 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 56.2 bits (134), Expect = 6e-08 Identities = 43/204 (21%), Positives = 101/204 (49%), Gaps = 17/204 (8%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 E L+EQ + +E + RL+E+ ++LR L E+ L + ++ + +++ Sbjct: 299 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMW 358 Query: 66 ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYR-----EKVNALQAQVCEL 120 E+ +RE+ RQ E+ WE+++Q ++ Q+ KM Q R E++ + ++ E Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQ--MREQEQKMRDQEERMWEQDERLREKEERMREQ 416 Query: 121 QKERDQAYSARDSAQ--------REISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAE 172 +K +Q R+ + R+ + + E++ +R + ++ ++ +R Q ++Q + Sbjct: 417 EKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 476 Query: 173 PPGVLKQEAR--TREPCPREKQRL 194 + +QE + ++ P +K++L Sbjct: 477 EENMWEQEEKEWQQQRLPEQKEKL 500 Score = 55.5 bits (132), Expect = 1e-07 Identities = 53/196 (27%), Positives = 97/196 (49%), Gaps = 18/196 (9%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSL--AEKDILEQSLDEARGSRQE 63 E EL+EQ + +E + RL+E+ K+R + EK + EQ E R +E Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQE-KELREQEKE 336 Query: 64 LVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE 123 L E+ LRE+ + Q E+ WE++E+ ++ Q+ KM Q + ++ E +K+ Sbjct: 337 LREQ-KELREQEEQMQEQEEKMWEQEEK--MREQEEKMWRQ---------EERLWEQEKQ 384 Query: 124 -RDQAYSARDSAQR--EISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 180 R+Q RD +R E + L EK+ R+ ++ +QV ++R + + + E ++E Sbjct: 385 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE 444 Query: 181 ARTREPCPREKQRLVR 196 E RE+++ +R Sbjct: 445 KMQEEERIREREKKMR 460 Score = 45.4 bits (106), Expect = 1e-04 Identities = 45/201 (22%), Positives = 96/201 (47%), Gaps = 22/201 (10%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQE-- 63 E ++QEQ +T DQE +E R++E +K+R ++ E++ Q +E ++E Sbjct: 429 EKKMQEQEKKTR-DQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 487 Query: 64 -LVERIHSLRERAVAAER---QREQYWEEKEQTLLQFQKSKMACQLYR-EKVNALQAQVC 118 +R+ +E+ E+ Q E+ WE++E+ Q + +++R EK+ + Q+ Sbjct: 488 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 547 Query: 119 EL-QKERDQAYSARDSAQR-------------EISQSLVEKDSLRRQVFELTDQVCELRT 164 E +K RDQ D +R + + + E++ +R + ++ ++ +R Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 607 Query: 165 QLRQLQAEPPGVLKQEARTRE 185 Q ++Q + + +QE + E Sbjct: 608 QEEKMQEQEEKMQEQEEKMWE 628 Score = 42.4 bits (98), Expect = 8e-04 Identities = 48/191 (25%), Positives = 96/191 (50%), Gaps = 21/191 (10%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 ELQE+ ++ E + +LN +KE KL F L + + +L E ++E Sbjct: 229 ELQEKL--PLAESEKSEIQLN-VKELKRKLERAKFLLPQ--VQTNTLQEEMWRQEE---- 279 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE-RDQ 126 LRE+ +Q E+ W ++E+ L+ Q+ KM Q EK+ + ++ E +KE R+Q Sbjct: 280 --ELREQEKKIRKQEEKMWRQEER--LREQEGKMREQ--EEKMWRQEKRLREQEKELREQ 333 Query: 127 AYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREP 186 R+ Q+E+ + +++ ++ Q ++ +Q ++R Q ++ + + +QE + RE Sbjct: 334 EKELRE--QKELRE---QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 388 Query: 187 CPREKQRLVRM 197 + + + RM Sbjct: 389 EQKMRDQEERM 399 Score = 40.0 bits (92), Expect = 0.004 Identities = 41/200 (20%), Positives = 97/200 (48%), Gaps = 16/200 (8%) Query: 7 LELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVE 66 L +E+ +R +QE E++ +++EE +K++ +++ Q + R +++ E Sbjct: 406 LREKEERMR---EQEKMWEQVEKMREE-KKMQEQEKKTRDQEEKMQEEERIREREKKMRE 461 Query: 67 RIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLY-REKVNALQAQVCEL-QKER 124 ++RE+ ++Q E WE++E+ Q + + +L+ +EK+ + ++ E +K R Sbjct: 462 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 521 Query: 125 DQAYS--------ARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGV 176 DQ ++ + + Q +++ +R Q ++ DQ E R + + + E Sbjct: 522 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ--EERMEKKTQEQEKKTW 579 Query: 177 LKQEARTREPCPREKQRLVR 196 ++E E RE+++ +R Sbjct: 580 DQEEKMREEERMREREKKMR 599 Score = 38.9 bits (89), Expect = 0.009 Identities = 37/189 (19%), Positives = 88/189 (46%), Gaps = 19/189 (10%) Query: 9 LQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERI 68 ++EQ + +E E+ ++ E+ EK++ + E++ +E +Q L E+ Sbjct: 605 MREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQK 664 Query: 69 HSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKER-DQA 127 L E E+++ Q EEK +++ KM +K + + + +K R +++ Sbjct: 665 EKLWEHEKMQEQEKMQEQEEK-----IWEQEKM-----EKKTQEQEKKTWDQEKMREEES 714 Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEAR--TRE 185 R+ RE E++ +R Q ++ +Q +++ Q ++ + + +QE + ++ Sbjct: 715 MREREKKMRE------EEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQ 768 Query: 186 PCPREKQRL 194 P +K++L Sbjct: 769 RLPEQKEKL 777 Score = 36.2 bits (82), Expect = 0.060 Identities = 32/190 (16%), Positives = 83/190 (43%), Gaps = 5/190 (2%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 +++ QE+ + E +E + + EK+R + + + + R +++ Sbjct: 678 KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQ 737 Query: 66 ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL-QKER 124 E+ ++E+ Q E+ WE++E+ Q + + +L+ + Q ++ E +K R Sbjct: 738 EQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMR 797 Query: 125 DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTR 184 DQ R ++ Q ++ +R Q ++ Q ++ Q ++ + + QE + Sbjct: 798 DQEEKMRGQEEKMRGQ----EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKME 853 Query: 185 EPCPREKQRL 194 E +++++ Sbjct: 854 EKMQGQEEKM 863 Score = 31.2 bits (69), Expect = 1.9 Identities = 24/154 (15%), Positives = 72/154 (46%), Gaps = 4/154 (2%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 ++QEQ + +E ++ +E + R E + EQ ++ R Q++ ++ Sbjct: 505 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE-EKMRDQEQKMWDQ 563 Query: 68 IHSLRERAVAAERQ---REQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKER 124 + ++ E++ +E+ E+E+ + +K + ++ RE+ +Q Q ++Q++ Sbjct: 564 EERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 623 Query: 125 DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQ 158 ++ + + Q + + +++ + Q ++ +Q Sbjct: 624 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 657 >gi|31982906 cingulin-like 1 [Homo sapiens] Length = 1302 Score = 55.1 bits (131), Expect = 1e-07 Identities = 44/210 (20%), Positives = 96/210 (45%), Gaps = 10/210 (4%) Query: 10 QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIH 69 Q+Q ++ E+L RLK E E R EK + ++ D SR +E + Sbjct: 915 QKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEK-LQKEMADIVEASRTSTLELQN 973 Query: 70 SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYS 129 L E R+ + + ++ L+ +KS++ ++++ ++ ++ + Q+ +D+A + Sbjct: 974 QLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALT 1033 Query: 130 ARDSAQREISQSLVE-------KDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEAR 182 R ++ + E KD R V ++ D+V +L +L + + + ++ +R Sbjct: 1034 KRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISR 1093 Query: 183 TREPCPREKQRLVRMHAICPRDDSDCSLVS 212 +RE + + L++ A R D +C +S Sbjct: 1094 SREQMEQLRNELLQERA--ARQDLECDKIS 1121 Score = 44.7 bits (104), Expect = 2e-04 Identities = 53/218 (24%), Positives = 100/218 (45%), Gaps = 43/218 (19%) Query: 8 ELQEQSLRTASDQE--SGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 E + +L+ A +E S D+E+++LKE+ + AE L +S++EA + + L Sbjct: 757 ERELTALKGALKEEVSSHDQEMDKLKEQYD---------AELQALRESVEEATKNVEVLA 807 Query: 66 ERIHS---------LRERAVAAERQREQ-YWEEKEQTLLQFQ-----------KSKMACQ 104 R ++ +R + + E ++ Q EE E+ + Q Q K+K + Sbjct: 808 SRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLK 867 Query: 105 LYREKVNALQAQVCELQKERDQAYSAR-------DSAQREISQSLVEKDSLRRQVFELTD 157 Y ++ L+ + +KE +A SAR ++AQ +SQ+ E+ L ++ E ++ Sbjct: 868 KYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESE 927 Query: 158 QVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLV 195 Q + QLR+L+ E +T E +E +V Sbjct: 928 Q----KEQLRRLKNEMENERWHLGKTIEKLQKEMADIV 961 Score = 42.7 bits (99), Expect = 6e-04 Identities = 44/180 (24%), Positives = 79/180 (43%), Gaps = 31/180 (17%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSL-TFSLAEKDILEQSLDEARGSRQELVE 66 ELQ Q +Q++ EE R++ E+LRS + E L+Q L+E+ G ++ +E Sbjct: 625 ELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLE 684 Query: 67 RIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQ 126 + ++ +REQ+ E + LQ Q+ E+ E D Sbjct: 685 ELFQVK-------MEREQHQTE---------------------IRDLQDQLSEMHDELDS 716 Query: 127 AYSARDSAQREISQSLVE-KDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185 A + D + + + L++ K L+ + +Q LR + R+L A G LK+E + + Sbjct: 717 AKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTA-LKGALKEEVSSHD 775 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 54.3 bits (129), Expect = 2e-07 Identities = 40/191 (20%), Positives = 94/191 (49%), Gaps = 11/191 (5%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 E L+EQ + +E + RL+E+ ++LR L E+ L + ++ + +++ Sbjct: 261 EERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMW 320 Query: 66 ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125 E+ +RE+ RQ E+ WE+++Q Q QK + + E+ L+ + E +E++ Sbjct: 321 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE-ERMREQE 379 Query: 126 QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEAR--T 183 + + + Q E++ +R + ++ ++ +R Q ++Q + + +QE + Sbjct: 380 KMWEQEEKMQ--------EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ 431 Query: 184 REPCPREKQRL 194 ++ P +K++L Sbjct: 432 QQRLPEQKEKL 442 Score = 50.1 bits (118), Expect = 4e-06 Identities = 53/224 (23%), Positives = 103/224 (45%), Gaps = 12/224 (5%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 E ++E+ + ++E E+ +++E+ EK+R + E++ Q +E ++E + Sbjct: 559 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 618 Query: 66 ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125 +E + Q E WE++E+ +Q Q+ KM Q EK+ + ++ E Q+E+ Sbjct: 619 WE----QEEEDKMQEQEEMMWEQEEK--MQEQEEKMWEQ--EEKMREQEEKMRE-QEEKM 669 Query: 126 QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185 Q + Q E Q EK +R Q ++ Q ++ Q ++ + + QE RE Sbjct: 670 QGQEEKMREQEEKMQGQEEK--MREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQE-EMRE 726 Query: 186 PCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRE 229 R + + +M P + CS S++L ++S T S E Sbjct: 727 KEERIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVE 770 Score = 49.3 bits (116), Expect = 7e-06 Identities = 41/191 (21%), Positives = 98/191 (51%), Gaps = 11/191 (5%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 E +++EQ + +E E+ RL+E+ E++R + E++ Q + R +++ Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQE-KMWEQEEKMQEEERIREREKKMR 402 Query: 66 ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125 E ++RE+ ++Q E WE++E+ ++Q+ ++ Q +EK+ + + +K + Sbjct: 403 EEEETMREQEEKMQKQEENMWEQEEK---EWQQQRLPEQ--KEKLWEQEKMQEQEEKIWE 457 Query: 126 QAYSARDSAQREI---SQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEAR 182 Q RD Q E+ + + ++ +R Q ++ +Q ++R Q +++ + + +Q+ R Sbjct: 458 QEEKIRD--QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515 Query: 183 TREPCPREKQR 193 RE R +++ Sbjct: 516 LREKEERMREQ 526 Score = 43.9 bits (102), Expect = 3e-04 Identities = 50/191 (26%), Positives = 99/191 (51%), Gaps = 21/191 (10%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 ELQE+ LR A ++S + +LN +KE KL F L + + +L E ++E Sbjct: 191 ELQEK-LRLAESEKS-EIQLN-VKELKRKLERAKFLLPQ--VQTNTLQEEMWRQEE---- 241 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE-RDQ 126 LRE+ +Q E+ W ++E+ L+ Q+ KM Q EK+ + ++ E +KE R+Q Sbjct: 242 --ELREQEKKIRKQEEKMWRQEER--LREQEGKMREQ--EEKMRRQEKRLREQEKELREQ 295 Query: 127 AYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREP 186 R+ Q+++ + +++ ++ Q ++ +Q ++R Q ++ + + +QE + RE Sbjct: 296 EKELRE--QKKLRE---QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 350 Query: 187 CPREKQRLVRM 197 + + + RM Sbjct: 351 EQKMRDQEERM 361 Score = 34.3 bits (77), Expect = 0.23 Identities = 33/183 (18%), Positives = 82/183 (44%), Gaps = 14/183 (7%) Query: 14 LRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRE 73 ++T + QE + L+E+ +K+R + + E+ L E G +E E++ Sbjct: 227 VQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ---EERLREQEGKMREQEEKM----- 278 Query: 74 RAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDS 133 R++E+ E+E+ L + +K + RE+ +Q Q ++ ++ ++ + Sbjct: 279 ------RRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332 Query: 134 AQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQR 193 R+ + ++ +R Q ++ DQ + Q +L+ + + +QE + +++ Sbjct: 333 MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEE 392 Query: 194 LVR 196 +R Sbjct: 393 RIR 395 Score = 32.0 bits (71), Expect = 1.1 Identities = 39/192 (20%), Positives = 86/192 (44%), Gaps = 34/192 (17%) Query: 10 QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSR--QELVER 67 QE+ +R +Q+ D+E R+ E++E+LR + E+ + Q ++ R + QE ++ Sbjct: 491 QEEKMRD-QEQKMWDQE-ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK 548 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127 E+ ER RE+ + +E+ ++ RE+ +Q Q +++++ ++ Sbjct: 549 TWDQEEKMREEERMREREKKMREEE-----------EMMREQEEKMQEQEEKMREQEEKM 597 Query: 128 YSARDSAQREISQSLVEK--------------DSLRRQVFELTDQVCELRTQLRQLQAEP 173 + Q E Q EK D ++ Q + +Q +++ Q ++ + Sbjct: 598 WE-----QEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE 652 Query: 174 PGVLKQEARTRE 185 + +QE + RE Sbjct: 653 EKMREQEEKMRE 664 >gi|46852390 coiled-coil domain containing 6 [Homo sapiens] Length = 474 Score = 54.3 bits (129), Expect = 2e-07 Identities = 67/252 (26%), Positives = 122/252 (48%), Gaps = 21/252 (8%) Query: 9 LQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSR-QELVER 67 LQ++ A + E +E L NE R L EK LEQ L++ + + +L+++ Sbjct: 123 LQKEKETLAVNYEKEEEFLT-----NELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKK 177 Query: 68 IHSLRERAVAAERQREQYWEEK---EQTLLQFQKSKMACQLYREKVNALQAQVCELQKER 124 I L ++ + EQ EK E TL Q Q++ + +L++ +++ L+A+ LQ++ Sbjct: 178 IKKLENDTISKQLTLEQLRREKIDLENTLEQEQEA-LVNRLWK-RMDKLEAEKRILQEKL 235 Query: 125 DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAE----PPGVLKQE 180 DQ SA S R+IS + +++ R + L ++V L+ QLR Q + L++E Sbjct: 236 DQPVSAPPSP-RDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEE 294 Query: 181 ARTREPCPREKQRL----VRMHAICPRDDSDCSLVSSTESQLLSDLSATSSR-ELVDSFR 235 RE R +++L R A+C + S + + + +++SA R V S Sbjct: 295 RHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPI 354 Query: 236 SSSPAPPSQQSL 247 +P+P S + + Sbjct: 355 PYTPSPSSSRPI 366 >gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] Length = 2115 Score = 53.9 bits (128), Expect = 3e-07 Identities = 58/189 (30%), Positives = 90/189 (47%), Gaps = 23/189 (12%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 E Q Q +T QE + L E+ L+ SL +K EQ L E +QE + Sbjct: 530 EKQAQLAQTLQQQEQASQGLRHQVEQ------LSSSLKQK---EQQLKEV-AEKQEATRQ 579 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127 H+ ++ A AAE +RE E++ L Q + L +EK L+ LQ++ A Sbjct: 580 DHA-QQLATAAE-EREASLRERDAALKQLEA------LEKEKAAKLEI----LQQQLQVA 627 Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPC 187 ARDSAQ ++Q+ EK L R+V EL V R + + QA+ L+ + R+ + Sbjct: 628 NEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQ-VAELELQLRSEQQK 686 Query: 188 PREKQRLVR 196 EK+R+ + Sbjct: 687 ATEKERVAQ 695 Score = 41.6 bits (96), Expect = 0.001 Identities = 45/209 (21%), Positives = 84/209 (40%), Gaps = 19/209 (9%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 ELEL+ R ++ D ++ +++ ++L L A + + L+E R + L Sbjct: 232 ELELELAENRKLLTEK--DAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLT 289 Query: 66 ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125 R+H ++ + ++ Q + Q + + + + LQ + EL +E Sbjct: 290 MRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHS 349 Query: 126 QA----YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPP------- 174 +A + ++E+S +L +K L + L ++ +L L QLQ PP Sbjct: 350 KATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVL 409 Query: 175 ------GVLKQEARTREPCPREKQRLVRM 197 LKQEA T + Q V M Sbjct: 410 GDVLQLETLKQEAATLAANNTQLQARVEM 438 Score = 41.2 bits (95), Expect = 0.002 Identities = 63/285 (22%), Positives = 120/285 (42%), Gaps = 39/285 (13%) Query: 9 LQEQSLRTASDQESGDEELNRLK-------EENEKLRSLTFSLAEKDILEQ--------S 53 LQE +++E D+EL +L+ +E E+LR L E+ ++ + Sbjct: 1048 LQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGA 1107 Query: 54 LDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREK-VNA 112 EA G + ++ +LR E+Q ++ +E+ +L + +++ A + R+ + Sbjct: 1108 QSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQ-QEQADSLERSLEAERASRAERDSALET 1166 Query: 113 LQAQVCELQKERDQAYSARDSAQREISQSLVE-------KDSLRRQVFELTDQVCELRTQ 165 LQ Q+ E +E + SA SAQRE++ + +D + QV Q E + Sbjct: 1167 LQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVAR-GRQEAERKNS 1225 Query: 166 LRQLQAEPPGVLKQEARTREPCPREKQRLV------------RMHAICPRDDSDCSLVSS 213 L E +L ++ +E +E +RLV R+ + S+ + + Sbjct: 1226 LISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAE 1285 Query: 214 TESQLLSDLSATSSRELVDSFRSSSPAPPSQQSLYKRVAEDFGEE 258 S L ++ S RE + R +S + + AE+ G+E Sbjct: 1286 RSSALREEVQ--SLREEAEKQRVASENLRQELTSQAERAEELGQE 1328 Score = 38.9 bits (89), Expect = 0.009 Identities = 49/228 (21%), Positives = 88/228 (38%), Gaps = 13/228 (5%) Query: 31 KEENEKLRSLTFSLAEKD----ILEQSLDEARGSRQELVERIHSLRERAVAAERQREQYW 86 +E+ +++ L+ LA+ D + +Q L + E + L+ + + Q Q Sbjct: 1545 REQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKE 1604 Query: 87 EEKEQTLLQFQKSKMACQLYREKVNALQAQVC---ELQKERDQAYSARDSAQREISQSLV 143 + E LQ +K+K +++ LQ Q+ +LQKE + + + E+ Q+ + Sbjct: 1605 QAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGL 1664 Query: 144 EKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLVRMHAICPR 203 + + LT QV L Q+ + + K + T RE Q ++ Sbjct: 1665 KTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSI-- 1722 Query: 204 DDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSP----APPSQQSL 247 D D S T + S L T +SP PP +SL Sbjct: 1723 DSLDLSCEEGTPLSITSKLPRTQPDGTSVPGEPASPISQRLPPKVESL 1770 Score = 37.7 bits (86), Expect = 0.021 Identities = 75/329 (22%), Positives = 127/329 (38%), Gaps = 41/329 (12%) Query: 35 EKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLL 94 E R + E +++ + A+ E +R R++ A Q E + E+ + + Sbjct: 1493 EVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVE 1552 Query: 95 QFQK----SKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRR 150 + K S A ++ ++K+ A+QAQ E Q+E + + + Q ++SQ + + Sbjct: 1553 ELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKL 1612 Query: 151 QVFEL-------TDQVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLVRMHAICPR 203 Q+ + Q EL+ QLR L+ + K+ R R L + Sbjct: 1613 QMEKAKTHYDAKKQQNQELQEQLRSLEQ----LQKENKELRAEAERLGHELQQAGLKTKE 1668 Query: 204 DDSDC----SLVSSTESQL------LSDLSATSSRELVDSFRSSSPAPPSQQSLYKRVAE 253 + C + V S E+Q+ L DL + D+ +S P Q L + Sbjct: 1669 AEQTCRHLTAQVRSLEAQVAHADQQLRDLG--KFQVATDALKSREPQAKPQLDLSIDSLD 1726 Query: 254 DFGEE--PWSFSSCLEIPEGDPGALPGAKAG------DPHLD-YELLDTADLP-----QL 299 EE P S +S L + D ++PG A P ++ E L +P L Sbjct: 1727 LSCEEGTPLSITSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPL 1786 Query: 300 ESSLQPVSPGRLDVSESGVLMRRRPARRI 328 ESSL + LD RRR + I Sbjct: 1787 ESSLDSLGDVFLDSGRKTRSARRRTTQII 1815 Score = 37.4 bits (85), Expect = 0.027 Identities = 50/239 (20%), Positives = 96/239 (40%), Gaps = 14/239 (5%) Query: 4 SCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQE 63 S ++E + + TA ++ E ++ E +LRS EK+ + Q D+ + Q Sbjct: 649 SRKVEELQACVETARQEQH--EAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQA 706 Query: 64 LVERI--------HSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQA 115 L E + R A A E Q+ E K +T ++ K + E+ + Sbjct: 707 LKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKG 766 Query: 116 QVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPP- 174 LQ+ + + + +RE+++++ + + + +L +V R + Q E Sbjct: 767 LEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQ 826 Query: 175 -GVLKQE--ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSREL 230 G + QE +E C + +Q L +S L S + L++L A +R L Sbjct: 827 YGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARAL 885 Score = 34.7 bits (78), Expect = 0.17 Identities = 50/223 (22%), Positives = 95/223 (42%), Gaps = 26/223 (11%) Query: 25 EELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQ--ELVERIHSLRERAVAAERQR 82 E+L LKEE EK R EK +S E + SRQ EL E +H+ RA+ Sbjct: 833 EQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAE-LHANLARAL------ 885 Query: 83 EQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSL 142 Q +EKE ++ QK +EK+ A +V L+ +A +++A RE+ + Sbjct: 886 -QQVQEKE---VRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEP 941 Query: 143 VEKDSLRRQVFELTD--QVCELRTQLRQLQAEP-----------PGVLKQEARTREPCPR 189 + + E Q C + L+ ++ E +++ + + +E + Sbjct: 942 ARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQ 1001 Query: 190 EKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVD 232 +++ + R+ R +D +L + ++L L + + V+ Sbjct: 1002 QEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVE 1044 Score = 34.7 bits (78), Expect = 0.17 Identities = 44/200 (22%), Positives = 77/200 (38%), Gaps = 21/200 (10%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 + E S R A + EE+ L+EE EK R + +L RQEL Sbjct: 1273 QAETASNSARAAERSSALREEVQSLREEAEKQRVASENL----------------RQELT 1316 Query: 66 ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125 + E + +E+++ +KEQ L Q + Q ++ + +LQ E+ Sbjct: 1317 SQAERAEELGQELKAWQEKFF-QKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQ- 1374 Query: 126 QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185 +A + E+ QS LR ++ ++ EL LRQ AE +Q + Sbjct: 1375 --AAAEKRHREELEQSKQAAGGLRAELLRAQRELGEL-IPLRQKVAEQERTAQQLRAEKA 1431 Query: 186 PCPREKQRLVRMHAICPRDD 205 + L + H + ++ Sbjct: 1432 SYAEQLSMLKKAHGLLAEEN 1451 Score = 34.3 bits (77), Expect = 0.23 Identities = 44/191 (23%), Positives = 80/191 (41%), Gaps = 33/191 (17%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEK-----DILEQSLDEARGS 60 E E Q LR +++ S E+L+ LK+ + L L E+ LE LD+AR Sbjct: 1418 EQERTAQQLR--AEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREK 1475 Query: 61 --------RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNA 112 R + R+ ++ A + R+ E + E ++ + + Q R+K+ A Sbjct: 1476 YVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTA 1535 Query: 113 LQAQVCELQKERDQAYSARDSAQREISQSLVEKD-----------SLRRQVFELTDQVCE 161 Q+ Q+E+ + E+S+ L + D +++ Q E + Sbjct: 1536 QVEQLEVFQREQTKQV-------EELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQR 1588 Query: 162 LRTQLRQLQAE 172 L+ QL +LQA+ Sbjct: 1589 LQAQLNELQAQ 1599 Score = 32.0 bits (71), Expect = 1.1 Identities = 52/226 (23%), Positives = 96/226 (42%), Gaps = 29/226 (12%) Query: 2 VSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAE-KDILEQSLDEARGS 60 V E E +Q + +++ +EE +L L+S +L++ K+ LEQ+ +A G+ Sbjct: 436 VEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQA-SQAHGA 494 Query: 61 RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL 120 R L ++ SL +Q +++ L Q K K QAQ+ + Sbjct: 495 R--LTAQVASLTSELTTLNATIQQQ-DQELAGLKQQAKEK-------------QAQLAQT 538 Query: 121 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFE-----LTDQVCELRTQLRQLQA---E 172 ++++QA ++S SL +K+ ++V E D +L T + +A E Sbjct: 539 LQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRE 598 Query: 173 PPGVLKQ-EARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQ 217 LKQ EA +E K +++ + D + S T++Q Sbjct: 599 RDAALKQLEALEKEKA--AKLEILQQQLQVANEARDSAQTSVTQAQ 642 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 51.6 bits (122), Expect = 1e-06 Identities = 35/161 (21%), Positives = 78/161 (48%), Gaps = 9/161 (5%) Query: 10 QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIH 69 QE+ +R ++ EE +++E+ EK+R + E++ + Q +E G ++E ++ Sbjct: 507 QEEKIREQEEKMWRQEE--KIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE 564 Query: 70 SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYS 129 +R + Q E+ E+KE+ Q +K + RE+ +Q Q ++ ++ ++ Sbjct: 565 KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE 624 Query: 130 ARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ 170 + Q +++ +RRQ ++ +Q LR Q ++Q Sbjct: 625 QEEKMQE-------QEEKMRRQEEKMWEQEVRLRQQEEKMQ 658 Score = 42.4 bits (98), Expect = 8e-04 Identities = 42/188 (22%), Positives = 88/188 (46%), Gaps = 18/188 (9%) Query: 10 QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIH 69 Q+Q + +E E +++E+ EK+R E+ I EQ E + RQE Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIRE-----QEEKIREQ---EEKMRRQE-----E 342 Query: 70 SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYS 129 + E+ RQ E WE++E + ++ + EK+ L+ ++ E +K R+Q Sbjct: 343 MMWEKEEKMRRQEEMMWEKEE----KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK 398 Query: 130 ARDSAQ-REISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCP 188 ++ + RE + ++ + RQ ++ +Q ++R Q +++ + + +QE E Sbjct: 399 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 458 Query: 189 REKQRLVR 196 +E++ + R Sbjct: 459 QEQEEMWR 466 Score = 42.4 bits (98), Expect = 8e-04 Identities = 51/194 (26%), Positives = 91/194 (46%), Gaps = 26/194 (13%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 E E + Q +QE E+ ++ + EK+R E+ I EQ E + RQE Sbjct: 394 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE-----QEEKIREQ---EKKMWRQE-- 443 Query: 66 ERIHSLRERAVAAERQ-REQYWEE----KEQTLLQFQKSKMACQLYREKVNALQAQVC-E 119 E+IH + +RQ +E+ W + +EQ + QK KM Q EK+ + +V + Sbjct: 444 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ---EKIRKQEEKVWRQ 500 Query: 120 LQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQ 179 +K DQ R+ ++ Q ++ +R Q ++ +Q ++R Q +Q + + +Q Sbjct: 501 EEKMHDQEEKIREQEEKMWRQ----EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ 556 Query: 180 EARTREPCPREKQR 193 E + +E +EK R Sbjct: 557 EEKMQE---QEKMR 567 Score = 42.4 bits (98), Expect = 8e-04 Identities = 26/131 (19%), Positives = 63/131 (48%), Gaps = 6/131 (4%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 E+ ++ +QE +E +++ + EK+R E+ I EQ ++ R +++ E+ Sbjct: 544 EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIRE-----QEEKIREQK-EKIREQEEKIWEQ 597 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127 +RE+ + Q E+ WE++E+ Q +K + + R + + Q L+++ ++ Sbjct: 598 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 657 Query: 128 YSARDSAQREI 138 ++ + I Sbjct: 658 QEHQEHLEAAI 668 Score = 40.0 bits (92), Expect = 0.004 Identities = 41/199 (20%), Positives = 93/199 (46%), Gaps = 23/199 (11%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSL---AEKDILEQSLD------EAR 58 +LQE+ S++ + LK + E+ + L AE D L + L +A+ Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284 Query: 59 GSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVC 118 EL R++ +E + + ++ Q WEEK +Q Q+ K+ RE+ ++ Q Sbjct: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEK----IQEQEEKI-----REQEEKIREQEE 335 Query: 119 ELQKERDQAYSARDSAQREISQSLVEKDSLRR---QVFELTDQVCELRTQLRQLQ--AEP 173 +++++ + + + +R+ +++ +RR ++E +++ EL ++ + + E Sbjct: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ 395 Query: 174 PGVLKQEARTREPCPREKQ 192 ++E + RE R++Q Sbjct: 396 EEKRQEEEKIREQEKRQEQ 414 Score = 38.9 bits (89), Expect = 0.009 Identities = 25/176 (14%), Positives = 90/176 (51%), Gaps = 9/176 (5%) Query: 10 QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIH 69 +++ +R ++ EE ++ ++ EK+R +++ + + ++ R +++ E+ Sbjct: 486 EQEKIRKQEEKVWRQEE--KMHDQEEKIRE------QEEKMWRQEEKIREQEEKIREQEE 537 Query: 70 SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYS 129 +RE+ + Q E+ E++E+ + + +K + + RE+ ++ Q +++++ ++ + Sbjct: 538 KIREQEEMMQEQEEKMGEQEEK-MQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWE 596 Query: 130 ARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185 + + + +++ + Q ++ +Q +++ Q +++ + + +QE R R+ Sbjct: 597 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 652 Score = 38.5 bits (88), Expect = 0.012 Identities = 35/200 (17%), Positives = 92/200 (46%), Gaps = 10/200 (5%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 E ++QE + +E E+ +++E+ EK+R + EK+ + +E ++E + Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365 Query: 66 ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125 R+ + R+ E+ E+E+ Q +K R++ ++ Q E ++E++ Sbjct: 366 RRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK--------RQEEEKIREQ--EKRQEQE 415 Query: 126 QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185 ++ RE + + E++ + E + ++R + ++ + E +++ R +E Sbjct: 416 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 475 Query: 186 PCPREKQRLVRMHAICPRDD 205 R+K+++ I +++ Sbjct: 476 EIWRQKEKMHEQEKIRKQEE 495 Score = 35.8 bits (81), Expect = 0.078 Identities = 23/107 (21%), Positives = 57/107 (53%), Gaps = 10/107 (9%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 E +++EQ + +E E+ ++ E+ EK+R +++++++ ++ +++ Sbjct: 570 EEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE------QEEMMQEQEEKMWEQEEKMC 623 Query: 66 ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNA 112 E+ ++E+ RQ E+ WE ++ L+ Q+ KM Q ++E + A Sbjct: 624 EQEEKMQEQEEKMRRQEEKMWE--QEVRLRQQEEKM--QEHQEHLEA 666 Score = 34.7 bits (78), Expect = 0.17 Identities = 41/184 (22%), Positives = 86/184 (46%), Gaps = 26/184 (14%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKE---ENEKLRSLTFSL-AEKDILEQSLDEARGSR 61 E+ QE+ +R EE+ R KE E EK+R + +++ + ++ R Sbjct: 463 EMWRQEEKIRE-------QEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQE 515 Query: 62 QELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQ 121 +++ + +RE+ R++E+ E+E+ ++Q Q+ KM Q EK+ + + + Sbjct: 516 EKMWRQEEKIREQEEKI-REQEEKIREQEE-MMQEQEEKMGEQ--EEKMQEQEKMRRQEE 571 Query: 122 KERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEA 181 K R+Q R+ +K+ +R Q ++ +Q ++R Q +Q + + +QE Sbjct: 572 KIREQEEKIRE-----------QKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620 Query: 182 RTRE 185 + E Sbjct: 621 KMCE 624 >gi|21735548 centrosomal protein 2 [Homo sapiens] Length = 2442 Score = 51.2 bits (121), Expect = 2e-06 Identities = 58/236 (24%), Positives = 105/236 (44%), Gaps = 17/236 (7%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 E++ + R + QE G+ ++ + K E L LT +LAE+ E+ ++ RG QEL ++ Sbjct: 1394 EVESERERAQALQEQGELKVAQGKALQENLALLTQTLAER---EEEVETLRGQIQELEKQ 1450 Query: 68 IH-----------SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQ 116 L++R + Q+EQ +E E+ + MA Q +K+ + Q Sbjct: 1451 REMQKAALELLSLDLKKRNQEVDLQQEQI-QELEKCRSVLEHLPMAVQEREQKLTVQREQ 1509 Query: 117 VCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGV 176 + EL+K+R+ + + E+ + +S R QV +L Q+ L +L+ + Sbjct: 1510 IRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKM 1569 Query: 177 LKQEARTRE-PCPREKQRLVRMHAICPRDDSDCSL-VSSTESQLLSDLSATSSREL 230 Q+ +E RE QR+ H ++ L S++ L S +REL Sbjct: 1570 ECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLAREL 1625 Score = 45.4 bits (106), Expect = 1e-04 Identities = 49/200 (24%), Positives = 93/200 (46%), Gaps = 21/200 (10%) Query: 6 ELELQEQSLRTASDQESG--DEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQE 63 +L EQ +TA +Q+ ++E+N+L+E+ EK RS + L ++L+ + E Sbjct: 832 QLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSW-----HQQELAKALESLEREKME 886 Query: 64 LVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE 123 L R+ + A + QRE+ + E L Q Q + +E+V+ L+ + + QKE Sbjct: 887 LEMRLKEQQTEMEAIQAQREEERTQAESALCQMQ-----LETEKERVSLLET-LLQTQKE 940 Query: 124 RDQAYSARDSAQREIS-QSLVEKDS-------LRRQVFELTDQVCELRTQLRQLQAEPPG 175 A + ++++ Q L E+++ L+ EL + + R L LQ E Sbjct: 941 LADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSS 1000 Query: 176 VLKQEARTREPCPREKQRLV 195 +L+ + ++ K +LV Sbjct: 1001 LLQDKMDLQKQVEDLKSQLV 1020 Score = 44.3 bits (103), Expect = 2e-04 Identities = 61/233 (26%), Positives = 105/233 (45%), Gaps = 45/233 (19%) Query: 11 EQSLRTASDQESG-DEELNRLKEENEKLRSLTFSLA-EKDILEQSLDEARGSRQELVERI 68 EQS+ S E+ E+ L+ KL +L +LA +K L Q L + Q + R+ Sbjct: 574 EQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRM 633 Query: 69 HSLRERAVA-------AERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQ 121 + + A AE++RE WE+ Q QK++ E LQA + ++Q Sbjct: 634 EAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAE-------EAGAELQADLRDIQ 686 Query: 122 KERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEA 181 +E+++ Q+++S+S ++++ Q+ QL Q VL + Sbjct: 687 EEKEE-------IQKKLSESRHQQEAATTQL-----------EQLHQEAKRQEEVLARAV 728 Query: 182 RTREPCPREKQRL-VRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDS 233 + +E REK L VR+ A+ RD D ++ L LS S++EL++S Sbjct: 729 QEKEALVREKAALEVRLQAV-ERDRQDL-------AEQLQGLS--SAKELLES 771 Score = 44.3 bits (103), Expect = 2e-04 Identities = 55/228 (24%), Positives = 97/228 (42%), Gaps = 15/228 (6%) Query: 2 VSSCELELQEQSLRTASDQESGDEELNRLKEEN--EKLRSLTFSLAEK-------DILEQ 52 ++S + L+ L+ Q G+ EL + +EN ++ L ++ E ILE+ Sbjct: 1322 MASLQSRLRRAELQRMEAQ--GERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEE 1379 Query: 53 SLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNA 112 L AR + + E + S RERA A + Q E + + E+V Sbjct: 1380 DLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVET 1439 Query: 113 LQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTD--QVCELRTQLRQLQ 170 L+ Q+ EL+K+R+ +A + ++ + E D + Q+ EL V E Q + Sbjct: 1440 LRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQER 1499 Query: 171 AEPPGVLKQEARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQL 218 + V +++ R E RE QR V H + + D ++ S Q+ Sbjct: 1500 EQKLTVQREQIRELEK-DRETQRNVLEHQLLELEKKD-QMIESQRGQV 1545 Score = 42.0 bits (97), Expect = 0.001 Identities = 46/184 (25%), Positives = 77/184 (41%), Gaps = 33/184 (17%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLR-SLTFSLAEKD---------------- 48 E E+QE+ T +E NR+++E E+ + SLT SL EK+ Sbjct: 1030 EQEVQEKLRET--------QEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQE 1081 Query: 49 --ILEQSLDEARGSRQELVERIHSLRERAVAAE----RQREQYWEEKEQTLLQFQKSKMA 102 L Q + EA+G ++EL ++ LR+ E Q Q EE E + + ++ Sbjct: 1082 LSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEAS--HITEQQLR 1139 Query: 103 CQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCEL 162 L+ ++ A Q Q+ E A + +Q+ + SL + + VCE Sbjct: 1140 ASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCES 1199 Query: 163 RTQL 166 R +L Sbjct: 1200 RPEL 1203 Score = 40.4 bits (93), Expect = 0.003 Identities = 45/193 (23%), Positives = 79/193 (40%), Gaps = 12/193 (6%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 ELQ Q D E D+EL KE + L + ILE+ L++ + S +E Sbjct: 1641 ELQRQKEHLTQDLERRDQELMLQKERIQVLEDQR--TRQTKILEEDLEQIKLSLRERGRE 1698 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127 + + +R + ER E K Q + K+ + ++V Q + ELQ+ +DQ Sbjct: 1699 LTT--QRQLMQERAEEGKGPSKAQRG-SLEHMKLILRDKEKEVECQQEHIHELQELKDQL 1755 Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQ-------LRQLQAEPPGVLKQE 180 R++ ++ + +++ L Q+ E R Q L+ E L Q Sbjct: 1756 EQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQR 1815 Query: 181 ARTREPCPREKQR 193 + E +E+Q+ Sbjct: 1816 DQELEALQQEQQQ 1828 Score = 39.3 bits (90), Expect = 0.007 Identities = 43/169 (25%), Positives = 75/169 (44%), Gaps = 6/169 (3%) Query: 20 QESGDEELNRLKEENEKLRSLTFSLAEK--DILEQSLDEARGSRQELVERIHSLRERAVA 77 Q SG E N L+ ++ + A+K ++ L R + Q+L +++ +E Sbjct: 361 QGSGHE--NSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNL 418 Query: 78 AERQREQYWEEKEQTLLQ-FQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQR 136 ++Q +Q WEE+ + L Q QK + LQ +V L KER+ AR+ ++ Sbjct: 419 LQQQHDQ-WEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQ 477 Query: 137 EISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185 ++ E LRR EL Q + Q + Q E +++ R +E Sbjct: 478 QLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQE 526 Score = 38.1 bits (87), Expect = 0.016 Identities = 41/171 (23%), Positives = 81/171 (47%), Gaps = 17/171 (9%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKD----ILEQSLDEARGSR 61 E+E Q++ + QE D+ +L+ + K+ + L++++ +L+Q L EAR Sbjct: 1737 EVECQQEHIHEL--QELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQG 1794 Query: 62 QELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQV---- 117 + + + S + A A QR+Q E +Q Q Q + + +EK +ALQ + Sbjct: 1795 ELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQE---ERVKEKADALQGALEQAH 1851 Query: 118 CELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQ 168 L++ + ++ A+R + VE R+V L + + +LR + R+ Sbjct: 1852 MTLKERHGELQDHKEQARRLEEELAVE----GRRVQALEEVLGDLRAESRE 1898 Score = 38.1 bits (87), Expect = 0.016 Identities = 53/252 (21%), Positives = 103/252 (40%), Gaps = 19/252 (7%) Query: 3 SSCELELQEQSLRTASDQESGDEELNRLKEEN------EKLRSLTFSLAEKDILEQSLDE 56 +S L +EQ + Q E LKE++ E R+L E + L+Q + Sbjct: 1769 TSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQ 1828 Query: 57 ARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQ 116 A+G + + E+ +L+ A ++ E + Q ++ + + +V AL+ Sbjct: 1829 AQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEV 1888 Query: 117 VCELQKERDQAYSARDSAQREISQSL----VEKDSLRRQVFELTDQVCELRTQLRQLQAE 172 + +L+ E + A + Q++ ++ VE +L+ + + E +L L+AE Sbjct: 1889 LGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAE 1948 Query: 173 PPGVLKQEARTREPCPREKQRLVRMHA--------ICPRDDSDCSLVSSTES-QLLSDLS 223 QE R ++ L + HA + + + SL +ST + Q D Sbjct: 1949 SQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDAC 2008 Query: 224 ATSSRELVDSFR 235 SR+L ++ R Sbjct: 2009 QAHSRQLEEALR 2020 Score = 37.4 bits (85), Expect = 0.027 Identities = 19/82 (23%), Positives = 46/82 (56%), Gaps = 7/82 (8%) Query: 98 KSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEK-------DSLRR 150 K++ + R++V L+ ++ + + E+ Q ++ QR++SQ+ EK +SL Sbjct: 1254 KTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLES 1313 Query: 151 QVFELTDQVCELRTQLRQLQAE 172 ++ EL + + L+++LR+ + + Sbjct: 1314 ELMELHETMASLQSRLRRAELQ 1335 Score = 35.4 bits (80), Expect = 0.10 Identities = 34/168 (20%), Positives = 73/168 (43%), Gaps = 1/168 (0%) Query: 24 DEELNRLKEENEKLRS-LTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAAERQR 82 + +L + +E +L++ L EK+ +++ L E+R ++ ++ L + A E Sbjct: 665 EAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVL 724 Query: 83 EQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSL 142 + +EKE + + ++ Q L Q+ L ++ S+ AQ++ S Sbjct: 725 ARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIE 784 Query: 143 VEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPRE 190 V K L Q+ +T ++ ++R L+ E Q + R+ R+ Sbjct: 785 VTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQ 832 Score = 34.7 bits (78), Expect = 0.17 Identities = 35/165 (21%), Positives = 74/165 (44%), Gaps = 14/165 (8%) Query: 7 LELQEQSLRTASDQESGDEE-LNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 L + Q+++ Q +G +E +N L++++++ E L Q L + G R L Sbjct: 395 LTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEE------EGKALRQRLQKLTGERDTLA 448 Query: 66 ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125 + L+ + ++RE + +E+ Q + + R +VN ELQ + D Sbjct: 449 GQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLR-RVNV------ELQLQGD 501 Query: 126 QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ 170 A ++ Q E+ ++ E++ L+ + L + E ++L L+ Sbjct: 502 SAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLR 546 Score = 29.6 bits (65), Expect = 5.6 Identities = 49/218 (22%), Positives = 92/218 (42%), Gaps = 31/218 (14%) Query: 8 ELQEQ-----SLRTASDQESGDEE--LNRLKEENEKLRSLTFSLAEKDI-LEQSLDEARG 59 ELQ++ +L T S +++ D E + L+E E L + L E + L ++ E + Sbjct: 280 ELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKL 339 Query: 60 SRQELVERIHSLRERA---VAAERQREQYWEEKEQTLLQFQ----------------KSK 100 S Q++++ I + +A E E QF + + Sbjct: 340 SLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRR 399 Query: 101 MACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVC 160 A Q R+++ Q V LQ++ DQ + ++ + + E+D+L Q +L +V Sbjct: 400 QAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVD 459 Query: 161 ELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLVRMH 198 L + R+L + L+Q+ E +E RL R++ Sbjct: 460 SLSKE-RELLQKAREELRQQLEVLE---QEAWRLRRVN 493 Score = 29.6 bits (65), Expect = 5.6 Identities = 44/169 (26%), Positives = 72/169 (42%), Gaps = 37/169 (21%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 ELE Q ++ R A + D L+E +++L++ + + + LE QE Sbjct: 1578 ELEGQRETQRVALTHLTLD-----LEERSQELQAQSSQIHD---LESHSTVLARELQERD 1629 Query: 66 ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125 + + S RE+ +RQ+E ++ E+ + Q LQKER Sbjct: 1630 QEVKSQREQIEELQRQKEHLTQDLER----------------------RDQELMLQKERI 1667 Query: 126 QAYSARDSAQREISQSLVE--KDSLRRQVFELTDQVCELRTQLRQLQAE 172 Q + + Q +I + +E K SLR + ELT Q QL Q +AE Sbjct: 1668 QVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQ-----RQLMQERAE 1711 >gi|145312241 differentially expressed in FDCP 6 homolog [Homo sapiens] Length = 631 Score = 51.2 bits (121), Expect = 2e-06 Identities = 65/279 (23%), Positives = 125/279 (44%), Gaps = 16/279 (5%) Query: 8 ELQEQSLRTASD----QESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQE 63 +LQE+ R + QE+ + L+EE E+ RS L + LE L EA +R Sbjct: 352 QLQEEKERKLQELELLQEAQRQAERLLQEEEERRRSQHRELQQA--LEGQLREAEQARAS 409 Query: 64 LVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE 123 + + L+E A +RQR + EE +Q L + + ++ + E V Q ++ E ++E Sbjct: 410 MQAEME-LKEEEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEE 468 Query: 124 R-DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQL----QAEPPGVLK 178 + Q ++ +R I ++ EK+ L++++ + + + + + QL ++ Q V Sbjct: 469 KLKQLMQLKEEQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEA 528 Query: 179 QEARTREPCPREKQRLVR----MHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSF 234 + + R+ K V+ MH I P D + S + Q SS + + + Sbjct: 529 AQRKLRQASTNVKHWNVQMNRLMHPIEPGDKRPVTSSSFSGFQPPLLAHRDSSLKRLTRW 588 Query: 235 RSSSPAPPSQQSLYKRVAEDFGEEPWSFSSCLEIPEGDP 273 S PS S ++ + + G+E + +S + + DP Sbjct: 589 GSQGNRTPSPNSNEQQKSLNGGDEAPAPASTPQEDKLDP 627 Score = 32.3 bits (72), Expect = 0.86 Identities = 35/133 (26%), Positives = 55/133 (41%), Gaps = 20/133 (15%) Query: 71 LRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSA 130 L+++ QRE+ KE+ LL+ Q QL EK LQ EL +E Sbjct: 325 LKQKRREQREQRERRRAAKEEELLRLQ------QLQEEKERKLQE--LELLQE------- 369 Query: 131 RDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPRE 190 AQR+ + L E++ RR Q L QLR+ + + + E R+ Sbjct: 370 ---AQRQAERLLQEEEERRRSQHRELQQA--LEGQLREAEQARASMQAEMELKEEEAARQ 424 Query: 191 KQRLVRMHAICPR 203 +QR+ + + R Sbjct: 425 RQRIKELEEMQQR 437 >gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] Length = 2017 Score = 51.2 bits (121), Expect = 2e-06 Identities = 52/209 (24%), Positives = 98/209 (46%), Gaps = 28/209 (13%) Query: 1 MVSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGS 60 +++ E E +E S A+ Q+ DE L L E+EK ++L+ +EK L + L R Sbjct: 1027 LLARLEAEKEELSEEIAALQQERDEGL--LLAESEKQQALSLKESEKTALSEKLMGTR-- 1082 Query: 61 RQELVERIHSLRERAVAAERQRE--QYWEEKEQTLLQFQKSKM---------ACQLYREK 109 HSL ++ ERQ+ Q +E++++ + S++ A + ++ Sbjct: 1083 --------HSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQE 1134 Query: 110 VNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQL 169 V LQ Q +L K+RD + + ++ +D LRR++ E ++ E + + R++ Sbjct: 1135 VRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQ-EGREV 1193 Query: 170 QAEPPGVLKQE----ARTREPCPREKQRL 194 Q + G L++ A+ RE R + L Sbjct: 1194 QRQEAGELRRSLGEGAKEREALRRSNEEL 1222 Score = 48.9 bits (115), Expect = 9e-06 Identities = 40/185 (21%), Positives = 82/185 (44%), Gaps = 22/185 (11%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSL-------------TFSLAE--KDILEQ 52 +L+E+ Q ++E +EE E+L L + +AE ++ LEQ Sbjct: 761 QLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQ 820 Query: 53 SLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNA 112 L R R +L E++ L + E++ EQ E ++ + +++ + ++ Sbjct: 821 QLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAG 880 Query: 113 LQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAE 172 L Q+ ++E + E ++ +EK++L +FE+ Q+ +L + QL+AE Sbjct: 881 LAVQLVAAERE-------GRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAE 933 Query: 173 PPGVL 177 +L Sbjct: 934 GQALL 938 Score = 44.7 bits (104), Expect = 2e-04 Identities = 64/269 (23%), Positives = 116/269 (43%), Gaps = 54/269 (20%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 +LE + Q+L A + +G EL L+++ + + + +K+++ Q L +A Q Sbjct: 929 QLEAEGQALLLAKETLTG--ELAGLRQQI--IATQEKASLDKELMAQKLVQAEREAQA-- 982 Query: 66 ERIHSLRERAVAAE-------RQREQYWEEKE------QTLLQFQKSKMACQLYREKVNA 112 SLRE+ A E R++E W E E Q+ LQ ++ ++ +L EK Sbjct: 983 ----SLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEK-EE 1037 Query: 113 LQAQVCELQKERD-----------QAYSARDSAQREISQSL-----------VEKDSLRR 150 L ++ LQ+ERD QA S ++S + +S+ L +E + +R Sbjct: 1038 LSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKR 1097 Query: 151 QVFELTDQ----VCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLVRMHAICPRDDS 206 +Q V L ++LR L+A+ A+ + + L + C R+ Sbjct: 1098 DAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAE 1157 Query: 207 DCSLVSSTESQLLSDLSATSSRELVDSFR 235 + T+ +LL D REL+++ R Sbjct: 1158 EL----RTQLRLLEDARDGLRRELLEAQR 1182 Score = 43.1 bits (100), Expect = 5e-04 Identities = 51/203 (25%), Positives = 86/203 (42%), Gaps = 18/203 (8%) Query: 7 LELQEQSLRTASD-----QESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSR 61 LE Q Q LR +D E E+ RL+ NE L EK L SL A+ Sbjct: 566 LEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSR------EKSNLAHSLQVAQQQA 619 Query: 62 QELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQ 121 +EL + L+ RQR++ EE+E + + + + ++ L+ + L Sbjct: 620 EELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLA 679 Query: 122 KERDQAYSA--RDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGV--- 176 KE + A R + QR++ Q+ EK + + + EL + +L+AE + Sbjct: 680 KELVEVREALSRATLQRDMLQA--EKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDS 737 Query: 177 LKQEARTREPCPREKQRLVRMHA 199 L + + E ++K L R+ A Sbjct: 738 LSKLSALNESLAQDKLDLNRLVA 760 Score = 40.4 bits (93), Expect = 0.003 Identities = 59/246 (23%), Positives = 110/246 (44%), Gaps = 29/246 (11%) Query: 11 EQSLRTASD-QESGDEELNRLKEENEKLRSLTFSLAEK-DILEQSLDEARGSRQELVERI 68 E SLR A QE+ +++L L+ E +L+ L+ + EQ L++AR Q VE + Sbjct: 805 EGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEAL 864 Query: 69 H--------------SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLY--REKVNA 112 L + VAAER+ E E T L+ +K + L+ + ++ Sbjct: 865 ERAAREKEALAKEHAGLAVQLVAAEREGRTLSE--EATRLRLEKEALEGSLFEVQRQLAQ 922 Query: 113 LQAQVCELQKERDQAYSARDSAQREIS---QSLV---EKDSLRRQVF--ELTDQVCELRT 164 L+A+ +L+ E A+++ E++ Q ++ EK SL +++ +L E + Sbjct: 923 LEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQA 982 Query: 165 QLRQLQAEPPGVLKQEARTREPCPRE-KQRLVRMHAICPRDDSDCSLVSSTESQLLSDLS 223 LR+ +A L++ R +E RE + ++ + R+ + E + LS+ Sbjct: 983 SLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEI 1042 Query: 224 ATSSRE 229 A +E Sbjct: 1043 AALQQE 1048 Score = 37.7 bits (86), Expect = 0.021 Identities = 68/328 (20%), Positives = 139/328 (42%), Gaps = 34/328 (10%) Query: 50 LEQSLDEARGSRQELVERIHSLRERAVAA-----ERQREQYWEEKEQTLLQFQKSKMACQ 104 L + L ++ R+ L E++ LR++ A + QRE LL +KS +A Sbjct: 552 LRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHS 611 Query: 105 LY---------REKVNALQAQVCELQKERDQAYSARDSA-------QREISQSLVEKDSL 148 L R++ LQA EL+++RD+ ++ A +RE+ +S + + L Sbjct: 612 LQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQL 671 Query: 149 RRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLVRMHAICPRDDSDC 208 + L ++ E+R L + + + ++A E + + V + + ++ Sbjct: 672 EGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEE 731 Query: 209 SLVSSTESQLLSDLSATSSRELVDSFRSSSPAPPSQQSLYKR---------VAEDFGEEP 259 + + + S+ LS L+ + +++ +D R + + +L R VA + E Sbjct: 732 ASLQDSLSK-LSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERL 790 Query: 260 WSFSSCLEIP-EGDPGALPGAKAGDPHLDYELLDTA-DLPQLESSLQPVSPGRLDVSESG 317 E+ +G G+L A+ L+ +L + QL+ L +S +L E Sbjct: 791 EELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLS-RQLSGREQE 849 Query: 318 VLMRRRPARRILSQVTMLAFQGDALLEQ 345 + RR A+R + + A + +AL ++ Sbjct: 850 LEQARREAQRQVEALERAAREKEALAKE 877 Score = 37.0 bits (84), Expect = 0.035 Identities = 64/267 (23%), Positives = 118/267 (44%), Gaps = 35/267 (13%) Query: 2 VSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSR 61 +++CE + Q R + +++ E + E++++L +A+ LE EA G Sbjct: 1756 LTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVAD---LELQRVEAEGQL 1812 Query: 62 QELVERIHSLRERAVAAERQREQYWEEK---EQTLLQFQKSKMACQLYREKVNALQAQVC 118 Q+L E + +E AA ++ +E+ ++ L Q++ QL EK ++ Sbjct: 1813 QQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRA--LAQLEAEK-REVERSAL 1869 Query: 119 ELQKERDQAYSARDSAQREISQS-------LVEKDSLRRQVFELTDQVCELRTQLRQLQA 171 L+K+R D +RE +S EK L R + ++ E + Q++QL+A Sbjct: 1870 RLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEA 1929 Query: 172 E--------PPGVLKQEARTRE-PCPREKQRLVRMHA-----ICPRDDSDCSLVSSTESQ 217 + P L+ +A+ ++ +E +RL A + R+ + V E Q Sbjct: 1930 QVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVRGLEEQ 1989 Query: 218 LLSDLSATSSRELVDSFRSSSP-APPS 243 +S L +EL RSS+P +PPS Sbjct: 1990 -VSTLKGQLQQEL---RRSSAPFSPPS 2012 Score = 35.8 bits (81), Expect = 0.078 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 6/88 (6%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 EL++Q LR + + L RL+EE ++ SL A +L + LD+A + Q L E Sbjct: 200 ELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNA---MLREQLDQAGSANQALSED 256 Query: 68 IHSLRERAVAAERQ---REQYWEEKEQT 92 I + ++ RE W +E++ Sbjct: 257 IRKVTNDWTRCRKELEHREAAWRREEES 284 Score = 35.0 bits (79), Expect = 0.13 Identities = 49/203 (24%), Positives = 79/203 (38%), Gaps = 24/203 (11%) Query: 4 SCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLT----FSLAEKDILEQSLDEARG 59 SC E +E + +++ D L E KLR E L +SL E Sbjct: 1151 SCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAK 1210 Query: 60 SRQELVERIHSLRERAVAAERQREQYW---EEKEQTLLQFQKSKMACQLYREKVNALQAQ 116 R+ L LR AE +R E+KEQ L ++++ A+ + Sbjct: 1211 EREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEAR----------TAVGKE 1260 Query: 117 VCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGV 176 EL+ + +R A+RE+ + LRRQ+ L + L +L +LQ Sbjct: 1261 AGELRTGLQEVERSRLEARRELQE-------LRRQMKMLDSENTRLGRELAELQGRLALG 1313 Query: 177 LKQEARTREPCPREKQRLVRMHA 199 + E +R +QRL++ A Sbjct: 1314 ERAEKESRRETLGLRQRLLKGEA 1336 Score = 35.0 bits (79), Expect = 0.13 Identities = 44/178 (24%), Positives = 81/178 (45%), Gaps = 24/178 (13%) Query: 17 ASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEA--------------RGSRQ 62 AS+ + EL R E E RS L++++ Q+L + G+ Q Sbjct: 1646 ASESRTVKLELQRRSLEGELQRS-RLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQ 1704 Query: 63 ELVERIHSLRERAVAAERQREQYWEEKEQTLLQ-FQKSKMACQLYREKVNALQAQVCELQ 121 VER++ A+A + E +K + L + +S + R+K LQ + + Sbjct: 1705 LTVERLNG----ALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACE 1760 Query: 122 KERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQ 179 +R D+A++ +S++ + SL QV L +V +L +L++++AE G L+Q Sbjct: 1761 HDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADL--ELQRVEAE--GQLQQ 1814 Score = 33.1 bits (74), Expect = 0.51 Identities = 47/250 (18%), Positives = 98/250 (39%), Gaps = 31/250 (12%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEAR--GSRQE 63 EL LQE+S+R + + + E + + +++ I + +E + G ++ Sbjct: 1580 ELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRR 1639 Query: 64 LVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE 123 L E + + R V E QR E Q+S++ + ALQ +V Sbjct: 1640 LKEVLDASESRTVKLELQRRSLEGE-------LQRSRLGLSDREAQAQALQDRV------ 1686 Query: 124 RDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEART 183 DS QR+++ S V+ +L+ V L + ++ L+ + G+ + A++ Sbjct: 1687 --------DSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQS 1738 Query: 184 REPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPAPPS 243 + + + + + D Q+L + + + L ++ + SS Sbjct: 1739 SASLNSTRDKNLHLQKALTACEHD--------RQVLQERLDAARQALSEARKQSSSLGEQ 1790 Query: 244 QQSLYKRVAE 253 Q+L VA+ Sbjct: 1791 VQTLRGEVAD 1800 Score = 32.3 bits (72), Expect = 0.86 Identities = 24/99 (24%), Positives = 45/99 (45%), Gaps = 5/99 (5%) Query: 121 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 180 Q+ERD+ + + R++++ E+DS + +L V E R + GV + Sbjct: 1522 QRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAEL 1581 Query: 181 ARTREPCPR-EKQRLVRMHAICPRDDSDCSLVSSTESQL 218 A E R E++R + + + S + +TES+L Sbjct: 1582 ALQEESVRRSERERRATLDQVATLERS----LQATESEL 1616 >gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens] Length = 636 Score = 50.8 bits (120), Expect = 2e-06 Identities = 50/215 (23%), Positives = 95/215 (44%), Gaps = 35/215 (16%) Query: 6 ELELQEQSLRTASDQ--ESGDEELNRLKEENEKLRSLTFSLAEKD--------------- 48 +L + ++L+ D+ E D+ RL+EEN +L+ L S K+ Sbjct: 214 QLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRPGSPKMEGTG 273 Query: 49 ---ILEQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQL 105 + Q + V + + ++ E+QR + E +Q F+ K Q Sbjct: 274 KKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMK---QQ 330 Query: 106 YREKVNALQAQVCELQKERDQAYSARDSAQRE------ISQSLVEKDSLRRQVFELTDQV 159 Y +K+ L+ ++ +LQK+ + R+ QR+ +++S +E + ++ +LT + Sbjct: 331 YEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKE--QLTAEA 388 Query: 160 CELRTQLRQLQAEPPGVLKQEARTREPCPREKQRL 194 ELR +++ LQ + L R RE +E QRL Sbjct: 389 KELRQKVKYLQDQ----LSPLTRQREYQEKEIQRL 419 Score = 35.0 bits (79), Expect = 0.13 Identities = 40/188 (21%), Positives = 83/188 (44%), Gaps = 29/188 (15%) Query: 24 DEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAAERQRE 83 D E R +++ + R L + ++ ++ E ++ +EL +++ L+++ RQRE Sbjct: 351 DLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQRE 410 Query: 84 QYWEEKEQTLLQFQKSKMACQ------------------LYREKVNALQAQVCELQKERD 125 Y E++ Q L + + ++ Q L R++ Q ++ + Q + Sbjct: 411 -YQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIF 469 Query: 126 QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185 + R+ + RE EK+ L++QV +L QV QL+ K E + RE Sbjct: 470 EEDFQRERSDRERMNE--EKEELKKQVEKLQAQVTLSNAQLK--------AFKDEEKARE 519 Query: 186 PCPREKQR 193 ++K++ Sbjct: 520 ALRQQKRK 527 Score = 29.3 bits (64), Expect = 7.3 Identities = 32/137 (23%), Positives = 58/137 (42%), Gaps = 9/137 (6%) Query: 9 LQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARG--SRQELVE 66 LQ+Q +E ++E+ RL + E+ S+ + S + A +QELV Sbjct: 398 LQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVT 457 Query: 67 RIHSLRERAVAAERQ-------REQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCE 119 + L+++ E RE+ EEKE+ Q +K + L ++ A + + Sbjct: 458 QNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKA 517 Query: 120 LQKERDQAYSARDSAQR 136 + R Q A+ S +R Sbjct: 518 REALRQQKRKAKASGER 534 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 50.4 bits (119), Expect = 3e-06 Identities = 35/165 (21%), Positives = 78/165 (47%), Gaps = 13/165 (7%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 E + QEQ + +E E+ +++E+ EK+R + E++ + Q +E G ++E Sbjct: 597 EEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEE-- 654 Query: 66 ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125 + E+ + Q E W ++E+ Q +K + + RE+ +Q Q ++ ++ + Sbjct: 655 ----KMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 710 Query: 126 QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ 170 + + Q +++ +RRQ ++ +Q LR Q ++Q Sbjct: 711 KMCEQEEKMQE-------QEEKMRRQEEKMWEQEVRLRQQEEKMQ 748 Score = 45.4 bits (106), Expect = 1e-04 Identities = 39/193 (20%), Positives = 88/193 (45%), Gaps = 20/193 (10%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 E ++QE + +E E+ +++E+ EK+R + EK+ + +E ++E + Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365 Query: 66 ERIHSLR-ERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKER 124 R + E+ RQ E WE++ EK+ L+ ++ E +K R Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEKE------------------EKIRELEEKMHEQEKIR 407 Query: 125 DQAYSARDSAQ-REISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEART 183 +Q ++ + RE + ++ + RQ ++ +Q ++R Q +++ + + +QE Sbjct: 408 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 467 Query: 184 REPCPREKQRLVR 196 E +E++ + R Sbjct: 468 EEEKRQEQEEMWR 480 Score = 42.4 bits (98), Expect = 8e-04 Identities = 32/177 (18%), Positives = 89/177 (50%), Gaps = 6/177 (3%) Query: 10 QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIH 69 QE+ +R + +E+++ E EK+ ++D + + ++ R +++ + Sbjct: 536 QEEKIREQEEMWREEEKMH----EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEE 591 Query: 70 SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYS 129 +RE+ + Q E+ W+++E+ Q +K + + RE+ ++ Q E+ +E+++ Sbjct: 592 KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQE-EMTQEQEEKMG 650 Query: 130 ARDSAQREISQSLVE-KDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185 ++ E + + E ++++ RQ ++ +Q ++R Q +++ + + +QE + E Sbjct: 651 EQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 707 Score = 37.7 bits (86), Expect = 0.021 Identities = 32/184 (17%), Positives = 81/184 (44%), Gaps = 7/184 (3%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 E ++ EQ ++ EE+ R + EK+ +K+ + + ++ R +++ Sbjct: 457 EEKIHEQEKIREEEKRQEQEEMWR---QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVW 513 Query: 66 ERIHSLRERAVAAERQREQYWEE----KEQTLLQFQKSKMACQLYREKVNALQAQVCELQ 121 + +RE+ Q E+ W + +EQ + ++ KM Q + Q Q ++ Sbjct: 514 RQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMW 573 Query: 122 KERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEA 181 ++ ++ + R+ + +++ + Q ++ Q ++R Q ++Q + + +QE Sbjct: 574 RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEE 633 Query: 182 RTRE 185 + RE Sbjct: 634 KIRE 637 Score = 37.4 bits (85), Expect = 0.027 Identities = 33/189 (17%), Positives = 88/189 (46%), Gaps = 29/189 (15%) Query: 19 DQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERI----HSLRER 74 ++E E+ +++ + EK+R + + E+ + E RQE E++ +RE+ Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQ---EEKIREQEEKRQEQEEKMWKQEEKIREQ 617 Query: 75 AVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCE----LQKERDQAYSA 130 + Q E+ E++E + ++ + Q EK+ + ++CE +Q++ + + Sbjct: 618 EEKIQEQEEKIREQEE----KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673 Query: 131 RDSAQREISQSLVEKDSLRRQ----------VFELTDQVCE----LRTQLRQLQAEPPGV 176 + + + + +++ +R Q ++E +++CE ++ Q +++ + + Sbjct: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733 Query: 177 LKQEARTRE 185 +QE R R+ Sbjct: 734 WEQEVRLRQ 742 Score = 34.3 bits (77), Expect = 0.23 Identities = 34/181 (18%), Positives = 80/181 (44%), Gaps = 6/181 (3%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSL---AEKDILEQSLDEARGSRQEL 64 +LQE+ S++ + LK + E+ + L AE D L + L Q Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284 Query: 65 VERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKER 124 VE + L R ++Q E+ W ++E+ +K + + RE+ ++ Q +++++ Sbjct: 285 VEE-NELWNRL--NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341 Query: 125 DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTR 184 + + + +R+ +++ +RRQ + ++ ++R Q + + + + E + Sbjct: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 401 Query: 185 E 185 E Sbjct: 402 E 402 >gi|4506467 radixin [Homo sapiens] Length = 583 Score = 50.4 bits (119), Expect = 3e-06 Identities = 35/186 (18%), Positives = 88/186 (47%), Gaps = 22/186 (11%) Query: 9 LQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERI 68 ++ Q ++ + +E ++L R + ENEK + ++I E+ + ++EL+ER+ Sbjct: 300 IEVQQMKAQAREEKHQKQLERAQLENEKKK--------REIAEKEKERIEREKEELMERL 351 Query: 69 HSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAY 128 + E+ + A+++ E ++++ A +L +E+ A + + L+KER A Sbjct: 352 KQIEEQTIKAQKELE-------------EQTRKALELDQERKRA-KEEAERLEKERRAAE 397 Query: 129 SARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCP 188 A+ + ++ + + ++ L ++ E T ++ L ++ + E + +E Sbjct: 398 EAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLE 457 Query: 189 REKQRL 194 + K+ L Sbjct: 458 KTKEEL 463 >gi|219521893 coiled-coil transcriptional coactivator isoform 2 [Homo sapiens] Length = 606 Score = 50.4 bits (119), Expect = 3e-06 Identities = 51/196 (26%), Positives = 86/196 (43%), Gaps = 29/196 (14%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEK-DILEQSLDEARGSRQELVE 66 +L Q +D+E + EL LKE+ + L S +K +L + L A +R + Sbjct: 234 KLLGQLKEVQADKEQSEAELEPLKEQLRGAQELAASSQQKATLLGEELASAAAARDRTIA 293 Query: 67 RIHSLRERAVAAE------------RQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQ 114 +H R R AE ++ + W ++ LLQ +++ ++K+ L Sbjct: 294 ELH--RSRLEVAEVNGRLAELGLHLKEEKCQWSKERAGLLQSVEAE------KDKILKLS 345 Query: 115 AQVCELQK----ERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ 170 A++ L+K ER Q + RE SLV+ +R++ EL + L+ + QLQ Sbjct: 346 AEILRLEKAVQEERTQNQVFKTELAREKDSSLVQLSESKRELTELRSALRVLQKEKEQLQ 405 Query: 171 AEPPGVL----KQEAR 182 E +L K EAR Sbjct: 406 EEKQELLEYMRKLEAR 421 Score = 30.4 bits (67), Expect = 3.3 Identities = 31/148 (20%), Positives = 63/148 (42%), Gaps = 7/148 (4%) Query: 32 EENEKLRSLTFSLAEKDILEQSLDEARGSRQELVE-------RIHSLRERAVAAERQREQ 84 EE + + + + +L+ LDE++ R +L++ ++ LR R ER Sbjct: 98 EEADGGSDILLVVPKATVLQNQLDESQQERNDLMQLKLQLEGQVTELRSRVQELERALAT 157 Query: 85 YWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVE 144 +E + + Q++ + E+ + L Q + + + ++ VE Sbjct: 158 ARQEHTELMEQYKGISRSHGEITEERDILSRQQGDHVARILELEDDIQTISEKVLTKEVE 217 Query: 145 KDSLRRQVFELTDQVCELRTQLRQLQAE 172 D LR V LT + +L QL+++QA+ Sbjct: 218 LDRLRDTVKALTREQEKLLGQLKEVQAD 245 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 49.7 bits (117), Expect = 5e-06 Identities = 47/181 (25%), Positives = 77/181 (42%), Gaps = 19/181 (10%) Query: 20 QESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAAE 79 QE + L+EE E+LR L ++ E+ + R R++ + R R E Sbjct: 261 QEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE 320 Query: 80 R-----QREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSA 134 R +REQ E +EQ L + Q+ + QL RE+ ++ER + R+ Sbjct: 321 RREQQERREQQEERREQQLRREQEERREQQLRREQ-----------EEERREQQLRREQE 369 Query: 135 QREISQSLVEKDSLRRQVFELTDQVCELRTQLR---QLQAEPPGVLKQEARTREPCPREK 191 + Q L + LRR+ +Q QLR QL+ E +Q+ R + RE+ Sbjct: 370 EERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 429 Query: 192 Q 192 + Sbjct: 430 E 430 Score = 48.9 bits (115), Expect = 9e-06 Identities = 64/263 (24%), Positives = 110/263 (41%), Gaps = 34/263 (12%) Query: 7 LELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVE 66 L+L+E+ R QE +++L R +EE + R E++ L+Q L + R+E E Sbjct: 489 LKLEEEERR--EQQERREQQLRREQEERREQRLKRQE--EEERLQQRLRSEQQLRREQEE 544 Query: 67 RIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYRE------KVNALQAQVCEL 120 R RE+ + E ++ E +EQ L + Q+ + L RE ++ Q + E Sbjct: 545 R----REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ 600 Query: 121 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 180 + +R++ +RE E + RRQ +++ E R Q QL+ E +Q Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ--QLRREQQERREQR 658 Query: 181 ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDS------F 234 + E R +QRL R H Q L++ +RE + S + Sbjct: 659 LKREEEEERLEQRLKREHE------------EERREQELAEEEQEQARERIKSRIPKWQW 706 Query: 235 RSSSPAPPSQQSLYKRVAEDFGE 257 + S A Q +Y R + G+ Sbjct: 707 QLESEADARQSKVYSRPRKQEGQ 729 Score = 46.2 bits (108), Expect = 6e-05 Identities = 56/207 (27%), Positives = 101/207 (48%), Gaps = 25/207 (12%) Query: 10 QEQSLRTASDQESGDEELNRLKEENEKLRSLTF--SLAEKDILEQSLDEARGSRQELVER 67 QE+ + ++E EE L+EE EK R + +KD L+Q +E + R+E +R Sbjct: 984 QEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ--EEEQLLREEREKR 1041 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYRE--KVNALQAQVCEL----- 120 RER R+ E+ +E+EQ L + ++++ +L R+ K LQ + +L Sbjct: 1042 RLQERERQY---REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098 Query: 121 ----QKERDQAYSARDSAQREISQSL-VEKDSLRRQVFELT-DQVCELRTQLRQLQAEPP 174 ++ER++ + Q+E Q L E++ RRQ E + E++ + QL E P Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEP 1158 Query: 175 -----GVLKQEARTREPCPREKQRLVR 196 L+++ R E +E+++L+R Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLR 1185 Score = 45.8 bits (107), Expect = 8e-05 Identities = 51/214 (23%), Positives = 89/214 (41%), Gaps = 23/214 (10%) Query: 6 ELELQEQSLRTASDQESGDEELNR---------------LKEENEKLRSLTFSLAEKDIL 50 E E +EQ LR ++E +++L R L+ E + R ++ Sbjct: 356 EEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 415 Query: 51 EQSLDEARGSRQELVERIHSL------RERAVAAERQREQYWEEKEQTLLQFQKSKMACQ 104 EQ L + R+E E H RE+ + E++ + W ++E+ + ++ + Q Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475 Query: 105 LYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFE-LTDQVCELR 163 L R++ + + +L++E + R Q Q + L+RQ E Q Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535 Query: 164 TQLRQLQAEP-PGVLKQEARTREPCPREKQRLVR 196 QLR+ Q E +LK+E R R +QRL R Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKR 569 Score = 45.4 bits (106), Expect = 1e-04 Identities = 59/267 (22%), Positives = 109/267 (40%), Gaps = 38/267 (14%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 EL+ +E+ R +QE E +L++E E+L + E+ + + +Q+ Sbjct: 912 ELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEE 971 Query: 66 ERIHSLRERAVAAERQR----EQYWEEKEQTLLQFQKSKMACQ----LYREKVNALQAQV 117 + + E+ ER++ E+ +++E+ LL+ ++ K Q YR+K Q + Sbjct: 972 QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEE 1031 Query: 118 CELQ--------KERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLR-- 167 L+ +ER++ Y + Q+E Q L E+ RR+ EL Q R Sbjct: 1032 QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQ--------ELERQYRKE 1083 Query: 168 -QLQAEPPGVLKQEARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATS 226 +LQ E +L++E R RE+Q C ++ L E L + Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERERQ--------CREEE---ELQQEEEQLLREEREKRR 1132 Query: 227 SRELVDSFRSSSPAPPSQQSLYKRVAE 253 +EL +R ++ L + E Sbjct: 1133 RQELERQYREEEEVQQEEEQLLREEPE 1159 Score = 44.7 bits (104), Expect = 2e-04 Identities = 42/185 (22%), Positives = 84/185 (45%), Gaps = 8/185 (4%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 E ++Q R D+ +EE ++ LR E++ L++ + + QE E+ Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRK------EEEKLQEEEPQRQRELQEEEEQ 277 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127 + L + + ERQ E+ +++ + Q ++ + + +++ Q + E Q+ER + Sbjct: 278 LRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQ 337 Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPC 187 R+ +R Q E++ RR+ +Q E R Q QL+ E +Q+ R + Sbjct: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEERREQ--QLRREQQLRREQQLRREQQL 395 Query: 188 PREKQ 192 RE+Q Sbjct: 396 RREQQ 400 Score = 44.3 bits (103), Expect = 2e-04 Identities = 43/174 (24%), Positives = 80/174 (45%), Gaps = 6/174 (3%) Query: 9 LQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERI 68 LQE+ + ++E EE L EE E R + E +E + R+E +R Sbjct: 1043 LQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102 Query: 69 HSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAY 128 RER R+ E+ +E+EQ L + ++ + +L R+ + Q E Q R++ Sbjct: 1103 RQERERQC---REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE 1159 Query: 129 SARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEAR 182 R ++E+ + E++ L+++ +L + E R Q R+ Q L+++ R Sbjct: 1160 KRR---RQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKR 1210 Score = 43.5 bits (101), Expect = 4e-04 Identities = 50/189 (26%), Positives = 84/189 (44%), Gaps = 21/189 (11%) Query: 20 QESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAAE 79 QE +E L+EE E+L+ + E+ E +QE + + RE+ E Sbjct: 896 QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE 955 Query: 80 RQR----EQYWEEKEQTLLQFQKSKMACQ----LYREKVNALQAQVCELQKER------- 124 R+R ++ ++KE+ LL + K Q YRE+ Q + L++ER Sbjct: 956 RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE 1015 Query: 125 -DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEART 183 ++ Y +D Q+E Q L E+ RR L ++ + R + +LQ E +L +E T Sbjct: 1016 WERQYRKKDELQQEEEQLLREEREKRR----LQERERQYREE-EELQQEEEQLLGEERET 1070 Query: 184 REPCPREKQ 192 R E+Q Sbjct: 1071 RRRQELERQ 1079 Score = 42.0 bits (97), Expect = 0.001 Identities = 51/186 (27%), Positives = 82/186 (44%), Gaps = 19/186 (10%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSR-QELVE 66 E +E+ LR Q+ L +E+ ++ R E LE+ R R Q+L E Sbjct: 792 EQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE 851 Query: 67 RIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQ 126 L+E R +EQ ++K + L+ ++ + LY + ALQ Q L+KE+ Sbjct: 852 EEDGLQEDQ-ERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKP--ALQEQ---LRKEQQL 905 Query: 127 AYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREP 186 + QRE E++ RRQ +Q + R + QLQ E +L++E R Sbjct: 906 LQEEEEELQRE------EREKRRRQ-----EQERQYREE-EQLQQEEEQLLREEREKRRR 953 Query: 187 CPREKQ 192 RE+Q Sbjct: 954 QERERQ 959 Score = 41.6 bits (96), Expect = 0.001 Identities = 56/220 (25%), Positives = 96/220 (43%), Gaps = 22/220 (10%) Query: 11 EQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHS 70 EQ LR Q+ +E +R E+E+L L E++ EQ L R+ L E Sbjct: 1601 EQQLRRQEGQQQLRQERDRKFREDEQL------LQERE--EQQLHRQERDRKFLEEEPQL 1652 Query: 71 LR-ERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYS 129 R ER R++ + E+EQ L + ++ ++ Q K + Q+ ++ER Sbjct: 1653 RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQE 1712 Query: 130 ARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPR 189 + ++E+ + E++ LR++ T+Q +LR Q R + +L++E E R Sbjct: 1713 EQQLRRQELERKFREEEQLRQE----TEQE-QLRRQERYRK-----ILEEEQLRPE---R 1759 Query: 190 EKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRE 229 E+Q+L R + + E QL S S RE Sbjct: 1760 EEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE 1799 Score = 40.0 bits (92), Expect = 0.004 Identities = 54/220 (24%), Positives = 95/220 (43%), Gaps = 34/220 (15%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDIL--------EQSLDEA 57 E + ++Q D++ DEEL R ++E ++ AE++ L E+ DE Sbjct: 152 EEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERR---AEEEQLQSCKGHETEEFPDEE 208 Query: 58 RGSRQELVERIHSLRERAVAAERQR---------EQYWEEKEQTL------LQFQKSKMA 102 + R+EL+E RE R+R E+ W ++E L LQ ++ + Sbjct: 209 QLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ 268 Query: 103 CQLYREKVNALQAQVCELQKERDQAYSARDSAQRE------ISQSLVEKDSLRRQVFELT 156 +L E+ + + EL++ER + + +RE + E+ RR+ E Sbjct: 269 RELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERR 328 Query: 157 DQVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLVR 196 +Q E R Q QL+ E +Q+ R + R +Q+L R Sbjct: 329 EQQEERREQ--QLRREQEERREQQLRREQEEERREQQLRR 366 Score = 40.0 bits (92), Expect = 0.004 Identities = 48/188 (25%), Positives = 84/188 (44%), Gaps = 15/188 (7%) Query: 10 QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARG--SRQELVER 67 +EQ LR +Q+ E+ R ++E E+ + L++ +E R R+E ER Sbjct: 409 REQQLRR--EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER 466 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127 H R +R +E+ E +E+ L K+ + RE+ + Q+ Q+ER + Sbjct: 467 -HEQERRKQQLKRDQEE--ERRERWL------KLEEEERREQQERREQQLRREQEERREQ 517 Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVC--ELRTQLRQLQAEPPGVLKQEARTRE 185 R + + Q L + LRR+ E +Q+ E +L Q + E +QE R + Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ 577 Query: 186 PCPREKQR 193 RE++R Sbjct: 578 LLKREEER 585 Score = 38.5 bits (88), Expect = 0.012 Identities = 55/203 (27%), Positives = 85/203 (41%), Gaps = 18/203 (8%) Query: 8 ELQEQSLRTASDQESGD------EELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGS- 60 +L+ Q LR +E E+ R K+E E+ +++ EQ +E R Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQ-EERREQQ 338 Query: 61 -RQELVERIHSLRERAVAAER-----QREQYWEEKEQTLLQFQKSKMACQLYREKVNALQ 114 R+E ER R ER +REQ E +EQ L + Q+ + QL RE+ + Sbjct: 339 LRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRRE 398 Query: 115 AQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPP 174 Q+ Q+ R + R+ R Q E++ R E + +L++ Q E Sbjct: 399 QQLRREQQLRREQQLRREQQLRREQQLRREQEEERH---EQKHEQERREQRLKREQEERR 455 Query: 175 GVLKQEART-REPCPREKQRLVR 196 LK+E T R R KQ+L R Sbjct: 456 DWLKREEETERHEQERRKQQLKR 478 Score = 38.5 bits (88), Expect = 0.012 Identities = 42/184 (22%), Positives = 86/184 (46%), Gaps = 20/184 (10%) Query: 7 LELQEQSLRTASDQESGDEELNRLKEENEKLRSLTF--SLAEKDILEQSLDEARGSRQEL 64 L+ ++Q R +++ +EE R + E E+LR + E++ L +E + RQE Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER 1769 Query: 65 ------VERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQL------YREKVNA 112 E++ RE ++ ++ + E+EQ + ++ ++ Q + E+ Sbjct: 1770 DRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQ 1829 Query: 113 LQAQVCELQKERDQAYSA------RDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQL 166 L+ Q L++ERD+ Y A ++ ++RE + E++ RRQ E + +R Q Sbjct: 1830 LEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQ 1889 Query: 167 RQLQ 170 ++ Q Sbjct: 1890 KEEQ 1893 Score = 37.0 bits (84), Expect = 0.035 Identities = 45/187 (24%), Positives = 75/187 (40%), Gaps = 14/187 (7%) Query: 7 LELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVE 66 LE + + R +QE ++L + +EE + R +++ LEQ L R E E Sbjct: 558 LEQERREQRLKREQEERRDQLLKREEERRQQR---LKREQEERLEQRLKREEVERLEQEE 614 Query: 67 RIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQ 126 R +R E +R+Q + +EQ + Q+ + Q RE Q E ++ER + Sbjct: 615 RREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE-----QRLKREEEEERLE 669 Query: 127 AYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREP 186 R+ + Q L E++ E + + R Q Q E +Q P Sbjct: 670 QRLKREHEEERREQELAEEEQ------EQARERIKSRIPKWQWQLESEADARQSKVYSRP 723 Query: 187 CPREKQR 193 +E QR Sbjct: 724 RKQEGQR 730 Score = 37.0 bits (84), Expect = 0.035 Identities = 46/194 (23%), Positives = 91/194 (46%), Gaps = 23/194 (11%) Query: 6 ELELQEQSLRTASDQESGDEE--LNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQE 63 +LE +EQ D++S +E+ L +EE + + E++ L Q +E RQE Sbjct: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357 Query: 64 LVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE 123 R RE + + Q ++ EE+++ Q ++ K L E+ Q + +L+++ Sbjct: 1358 ---RDRKFREEELRHQEQGRKFLEEEQRLRRQERERKF---LKEEQQLRCQEREQQLRQD 1411 Query: 124 RDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ-AEPPGVLKQEAR 182 RD+ + RE Q L ++ R+ ++ ++R Q R+ + E L+QE Sbjct: 1412 RDRKF-------REEEQQLSRQERDRK----FREEEQQVRRQERERKFLEEEQQLRQERH 1460 Query: 183 TREPCPREKQRLVR 196 + RE+++L++ Sbjct: 1461 RKF---REEEQLLQ 1471 Score = 36.6 bits (83), Expect = 0.046 Identities = 45/196 (22%), Positives = 80/196 (40%), Gaps = 17/196 (8%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLD-------EAR 58 E L+ + + +E ++ L R + E E+ + L S +++ +Q L E R Sbjct: 599 EQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQR 658 Query: 59 GSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVC 118 R+E ER+ +R ER+ ++ EE+++ + KS++ ++ + A Q Sbjct: 659 LKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSK 718 Query: 119 ELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLK 178 + R Q R Q E RR+ EL Q E R +Q + E Sbjct: 719 VYSRPRKQEGQRRRQEQEE---------KRRRRESELQWQE-EERAHRQQQEEEQRRDFT 768 Query: 179 QEARTREPCPREKQRL 194 + + E R +QRL Sbjct: 769 WQWQAEEKSERGRQRL 784 Score = 36.6 bits (83), Expect = 0.046 Identities = 50/198 (25%), Positives = 91/198 (45%), Gaps = 24/198 (12%) Query: 7 LELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVE 66 LE +EQ R Q+ +EE + L+E+ E+ RS +K L+E R R+ + Sbjct: 834 LEEEEQLQRRERAQQLQEEE-DGLQEDQERRRSQEQRRDQK--WRWQLEEERKRRRHTLY 890 Query: 67 RIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQ----LYREKVNALQAQVCEL-- 120 +L+E+ R+ +Q +E+E+ L + ++ K Q YRE+ Q + L Sbjct: 891 AKPALQEQL----RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946 Query: 121 ------QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPP 174 ++ER++ Y Q++ Q L E+ RR+ ++ + R + +LQ E Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR----QEREKKYREE-EELQQEEE 1001 Query: 175 GVLKQEARTREPCPREKQ 192 +L++E R E+Q Sbjct: 1002 QLLREEREKRRRQEWERQ 1019 Score = 36.6 bits (83), Expect = 0.046 Identities = 50/205 (24%), Positives = 89/205 (43%), Gaps = 28/205 (13%) Query: 6 ELELQEQSLRTASDQESGD-------EELNRLKE--------ENEKLRSLTFSLAEKDIL 50 EL+ Q++ R + + D E+ N +++ ENE+ R L S Sbjct: 1204 ELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQS 1263 Query: 51 EQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKV 110 +Q L G +QE RE+ +QR++++ E+EQ + QK R++ Sbjct: 1264 QQDLQHLLGEQQERD------REQERRRWQQRDRHFPEEEQLEREEQKEAKR----RDRK 1313 Query: 111 NALQAQVCELQKERDQAYSARDSAQREISQSLVEKDS--LRRQVFELTDQVCELRTQLRQ 168 + + Q+ ++E + D RE Q L E++ LRRQ + + ELR Q + Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG 1373 Query: 169 LQ-AEPPGVLKQEARTREPCPREKQ 192 + E L+++ R R+ E+Q Sbjct: 1374 RKFLEEEQRLRRQERERKFLKEEQQ 1398 Score = 35.0 bits (79), Expect = 0.13 Identities = 49/224 (21%), Positives = 93/224 (41%), Gaps = 29/224 (12%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 E++ +E+ L ++ +EL R E E+L+ EQ L E + R++ Sbjct: 1145 EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE---------EQLLREEQEKRRQ-- 1193 Query: 66 ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125 ER RE ++R+Q + +++ Q+S + Q EK NA++ + + Sbjct: 1194 ERERQYREEEELQRQKRKQRYRDED------QRSDLKWQWEPEKENAVRDNKVYCKGREN 1247 Query: 126 QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLR--------QLQAEPPGVL 177 + + + +Q QS + L + E + R Q R QL+ E Sbjct: 1248 EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREE---- 1303 Query: 178 KQEARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSD 221 ++EA+ R+ +E+++L+R R + E QLL + Sbjct: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQE 1347 Score = 34.3 bits (77), Expect = 0.23 Identities = 45/185 (24%), Positives = 82/185 (44%), Gaps = 12/185 (6%) Query: 8 ELQEQSL-RTASDQESGDEELN-RLKEENEKLRS--LTFSLAEKDILEQSLDEARGSRQ- 62 E +EQ L R D++ +EE R +E + K R L E+ LE+ R RQ Sbjct: 1472 EREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531 Query: 63 ELVERIHSLR--ERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL 120 + ++ LR ER + R++ + E+EQ + ++ +++ Q K + +V Sbjct: 1532 KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQ 1591 Query: 121 QKER----DQAYSARDSAQREISQSLVEKDSLRRQVF-ELTDQVCELRTQLRQLQAEPPG 175 ++ER D+ R Q+++ Q K Q+ E +Q + + R+ E P Sbjct: 1592 EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQ 1651 Query: 176 VLKQE 180 + +QE Sbjct: 1652 LRRQE 1656 Score = 30.8 bits (68), Expect = 2.5 Identities = 49/192 (25%), Positives = 83/192 (43%), Gaps = 23/192 (11%) Query: 6 ELELQEQSLRTASDQES---GDEELNRLKEENE-KLRSLTFSLAEKDILEQSLDEARGSR 61 EL QEQ + +++ + E LKEE + + + L + + +E + SR Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425 Query: 62 QELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQ 121 QE + ++ ER+R+ E+EQ L Q + K +RE+ LQ Sbjct: 1426 QERDRKFREEEQQVRRQERERKFL--EEEQQLRQERHRK-----FREEEQLLQ------- 1471 Query: 122 KERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ-AEPPGVLKQE 180 ER++ R R+ L E+ LRRQ + + ELR+Q + + E L ++ Sbjct: 1472 -EREEQQLHRQERDRKF---LEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQ 1527 Query: 181 ARTREPCPREKQ 192 R R+ E+Q Sbjct: 1528 QRQRKFLQEEQQ 1539 >gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo sapiens] Length = 1983 Score = 49.7 bits (117), Expect = 5e-06 Identities = 46/201 (22%), Positives = 98/201 (48%), Gaps = 14/201 (6%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDIL----EQSLDEARGSR 61 +L+L ++S+ A+ + EE +LK+++ +L L+ + ++ +L ++ + E + Sbjct: 1107 DLKLTQESVADAAQDKQQLEE--KLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARA 1164 Query: 62 QELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQ 121 +EL E + + R E+QR + E E+ + +++ A RE +A++ L+ Sbjct: 1165 EELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLR 1224 Query: 122 KERDQA-------YSARDSAQREISQSLVEK-DSLRRQVFELTDQVCELRTQLRQLQAEP 173 +E ++A +A Q E + L E+ DSL+R +L + ELR ++ L A Sbjct: 1225 RELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANV 1284 Query: 174 PGVLKQEARTREPCPREKQRL 194 + + +A + C + +L Sbjct: 1285 ETLTRAKASAEKLCRTYEDQL 1305 Score = 33.5 bits (75), Expect = 0.39 Identities = 39/170 (22%), Positives = 71/170 (41%), Gaps = 16/170 (9%) Query: 7 LELQEQSLRTASDQESGDEELNRLK------EENEKLRSLTFSLAEKDILEQSLDEARGS 60 LE ++ ++ A ++ G EL K E ++ + LAEKD +E Sbjct: 1582 LEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKD------EECANL 1635 Query: 61 RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCE- 119 R+ + SL+ A R R + K++ ++ + + QL A +AQ Sbjct: 1636 RRNHQRAVESLQASLDAETRARNEALRLKKK--MEGDLNDLELQLGHATRQATEAQAATR 1693 Query: 120 -LQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQ 168 +Q + + + RD QR ++ + +L R+ L ++ ELR L Q Sbjct: 1694 LMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQ 1743 Score = 30.8 bits (68), Expect = 2.5 Identities = 48/233 (20%), Positives = 102/233 (43%), Gaps = 31/233 (13%) Query: 4 SCELELQEQSL-RTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQ 62 + EL Q Q+L R AS + EEL E+ E+ R L AE+++LE + Sbjct: 1713 AAELHEQAQALERRASLLAAELEELRAALEQGERSRRL----AEQELLEAT--------- 1759 Query: 63 ELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVN------ALQAQ 116 ER++ L + Q+++ + Q + +++ + EK A+ A+ Sbjct: 1760 ---ERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAE 1816 Query: 117 VCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELT-----DQVCELRTQLRQLQA 171 EL+KE+D + + + ++ + Q++ E + + + QV +L ++R+L+A Sbjct: 1817 --ELKKEQDTS-AHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEA 1873 Query: 172 EPPGVLKQEARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSA 224 E K+ A + + ++R+ + D + + + +L S + + Sbjct: 1874 ELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKS 1926 >gi|205277396 dynactin 1 isoform 4 [Homo sapiens] Length = 1139 Score = 49.3 bits (116), Expect = 7e-06 Identities = 46/220 (20%), Positives = 92/220 (41%), Gaps = 16/220 (7%) Query: 10 QEQSLRTASDQESGDEELNRLK--EENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 +E+ LR E RLK E+ KL+ L + + +++ + + + +L R Sbjct: 82 EEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRR 141 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127 + R+ A A +E+Y EE T + + + ++ E+ +LQ +V E KER Sbjct: 142 LKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV-EALKER--- 197 Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPC 187 + + + + L+ ++ E QL+QL+ + + R R+ Sbjct: 198 ----------VDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLS 247 Query: 188 PREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSS 227 EKQ V++ + + + + +V +L +LS S Sbjct: 248 SSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAES 287 Score = 36.6 bits (83), Expect = 0.046 Identities = 56/264 (21%), Positives = 100/264 (37%), Gaps = 53/264 (20%) Query: 19 DQESGDEELNR-LKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVA 77 D+E+ +EL + LK + E+L L+ +LE+ LD A E +E++ + E A Sbjct: 813 DRETVIKELKKSLKIKGEELSEANVRLS---LLEKKLDSAAKDADERIEKVQTRLEETQA 869 Query: 78 AERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQRE 137 R++E+ +E E ++ALQA + +L+ E+ + +S + Sbjct: 870 LLRKKEKEFE--------------------ETMDALQADIDQLEAEKAELKQRLNSQSKR 909 Query: 138 ISQSL---------------------------VEKDSLRRQVFELTDQVCELRTQLRQLQ 170 + L V L + L Q+ +R + QLQ Sbjct: 910 TIEGLRGPPPSGIATLVSGIAGGAIPGQAPGSVPGPGLVKDSPLLLQQISAMRLHISQLQ 969 Query: 171 AEPPGVLKQEARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSR-E 229 E +LK + ++ P + + SQLL L+ S+ Sbjct: 970 HE-NSILKGAQMKASLASLPPLHVAKLSHEGPGSELPAGALYRKTSQLLETLNQLSTHTH 1028 Query: 230 LVDSFRSSSPAPPSQQSLYKRVAE 253 +VD R+S A L ++VA+ Sbjct: 1029 VVDITRTSPAAKSPSAQLMEQVAQ 1052 Score = 30.0 bits (66), Expect = 4.3 Identities = 25/118 (21%), Positives = 55/118 (46%), Gaps = 3/118 (2%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 EL+EQ +E + +R EK+R L ++ + + + + DE + + +E Sbjct: 291 ELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELE 350 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125 + + A A R+ ++ E ++T+ +Q++ + YR+ LQ EL +++ Sbjct: 351 LREQLDMAGARVREAQKRVEAAQETVADYQQT---IKKYRQLTAHLQDVNRELTNQQE 405 >gi|205277392 dynactin 1 isoform 3 [Homo sapiens] Length = 1253 Score = 49.3 bits (116), Expect = 7e-06 Identities = 46/220 (20%), Positives = 92/220 (41%), Gaps = 16/220 (7%) Query: 10 QEQSLRTASDQESGDEELNRLK--EENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 +E+ LR E RLK E+ KL+ L + + +++ + + + +L R Sbjct: 196 EEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRR 255 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127 + R+ A A +E+Y EE T + + + ++ E+ +LQ +V E KER Sbjct: 256 LKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV-EALKER--- 311 Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPC 187 + + + + L+ ++ E QL+QL+ + + R R+ Sbjct: 312 ----------VDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLS 361 Query: 188 PREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSS 227 EKQ V++ + + + + +V +L +LS S Sbjct: 362 SSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAES 401 Score = 36.6 bits (83), Expect = 0.046 Identities = 56/264 (21%), Positives = 100/264 (37%), Gaps = 53/264 (20%) Query: 19 DQESGDEELNR-LKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVA 77 D+E+ +EL + LK + E+L L+ +LE+ LD A E +E++ + E A Sbjct: 927 DRETVIKELKKSLKIKGEELSEANVRLS---LLEKKLDSAAKDADERIEKVQTRLEETQA 983 Query: 78 AERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQRE 137 R++E+ +E E ++ALQA + +L+ E+ + +S + Sbjct: 984 LLRKKEKEFE--------------------ETMDALQADIDQLEAEKAELKQRLNSQSKR 1023 Query: 138 ISQSL---------------------------VEKDSLRRQVFELTDQVCELRTQLRQLQ 170 + L V L + L Q+ +R + QLQ Sbjct: 1024 TIEGLRGPPPSGIATLVSGIAGGAIPGQAPGSVPGPGLVKDSPLLLQQISAMRLHISQLQ 1083 Query: 171 AEPPGVLKQEARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSR-E 229 E +LK + ++ P + + SQLL L+ S+ Sbjct: 1084 HE-NSILKGAQMKASLASLPPLHVAKLSHEGPGSELPAGALYRKTSQLLETLNQLSTHTH 1142 Query: 230 LVDSFRSSSPAPPSQQSLYKRVAE 253 +VD R+S A L ++VA+ Sbjct: 1143 VVDITRTSPAAKSPSAQLMEQVAQ 1166 Score = 30.0 bits (66), Expect = 4.3 Identities = 25/118 (21%), Positives = 55/118 (46%), Gaps = 3/118 (2%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 EL+EQ +E + +R EK+R L ++ + + + + DE + + +E Sbjct: 405 ELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELE 464 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125 + + A A R+ ++ E ++T+ +Q++ + YR+ LQ EL +++ Sbjct: 465 LREQLDMAGARVREAQKRVEAAQETVADYQQT---IKKYRQLTAHLQDVNRELTNQQE 519 >gi|13259508 dynactin 1 isoform 2 [Homo sapiens] Length = 1144 Score = 49.3 bits (116), Expect = 7e-06 Identities = 46/220 (20%), Positives = 92/220 (41%), Gaps = 16/220 (7%) Query: 10 QEQSLRTASDQESGDEELNRLK--EENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 +E+ LR E RLK E+ KL+ L + + +++ + + + +L R Sbjct: 82 EEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRR 141 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127 + R+ A A +E+Y EE T + + + ++ E+ +LQ +V E KER Sbjct: 142 LKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV-EALKER--- 197 Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPC 187 + + + + L+ ++ E QL+QL+ + + R R+ Sbjct: 198 ----------VDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLS 247 Query: 188 PREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSS 227 EKQ V++ + + + + +V +L +LS S Sbjct: 248 SSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAES 287 Score = 40.0 bits (92), Expect = 0.004 Identities = 57/254 (22%), Positives = 103/254 (40%), Gaps = 28/254 (11%) Query: 19 DQESGDEELNR-LKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVA 77 D+E+ +EL + LK + E+L L+ +LE+ LD A E +E++ + E A Sbjct: 813 DRETVIKELKKSLKIKGEELSEANVRLS---LLEKKLDSAAKDADERIEKVQTRLEETQA 869 Query: 78 AERQREQYWEEKEQTL------LQFQKSKMACQLYREKVNALQ-----------AQVCEL 120 R++E+ +EE L L+ +K+++ +L + ++ V + Sbjct: 870 LLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRGPPPSGIATLVSGI 929 Query: 121 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 180 E Q + A + + KDS L Q+ +R + QLQ E +LK Sbjct: 930 AGEEQQRGAIPGQAPGSVPGPGLVKDSPL-----LLQQISAMRLHISQLQHE-NSILKGA 983 Query: 181 ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSR-ELVDSFRSSSP 239 + ++ P + + SQLL L+ S+ +VD R+S Sbjct: 984 QMKASLASLPPLHVAKLSHEGPGSELPAGALYRKTSQLLETLNQLSTHTHVVDITRTSPA 1043 Query: 240 APPSQQSLYKRVAE 253 A L ++VA+ Sbjct: 1044 AKSPSAQLMEQVAQ 1057 Score = 30.0 bits (66), Expect = 4.3 Identities = 25/118 (21%), Positives = 55/118 (46%), Gaps = 3/118 (2%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 EL+EQ +E + +R EK+R L ++ + + + + DE + + +E Sbjct: 291 ELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELE 350 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125 + + A A R+ ++ E ++T+ +Q++ + YR+ LQ EL +++ Sbjct: 351 LREQLDMAGARVREAQKRVEAAQETVADYQQT---IKKYRQLTAHLQDVNRELTNQQE 405 >gi|13259510 dynactin 1 isoform 1 [Homo sapiens] Length = 1278 Score = 49.3 bits (116), Expect = 7e-06 Identities = 46/220 (20%), Positives = 92/220 (41%), Gaps = 16/220 (7%) Query: 10 QEQSLRTASDQESGDEELNRLK--EENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 +E+ LR E RLK E+ KL+ L + + +++ + + + +L R Sbjct: 216 EEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRR 275 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127 + R+ A A +E+Y EE T + + + ++ E+ +LQ +V E KER Sbjct: 276 LKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV-EALKER--- 331 Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPC 187 + + + + L+ ++ E QL+QL+ + + R R+ Sbjct: 332 ----------VDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLS 381 Query: 188 PREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSS 227 EKQ V++ + + + + +V +L +LS S Sbjct: 382 SSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAES 421 Score = 40.0 bits (92), Expect = 0.004 Identities = 57/254 (22%), Positives = 103/254 (40%), Gaps = 28/254 (11%) Query: 19 DQESGDEELNR-LKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVA 77 D+E+ +EL + LK + E+L L+ +LE+ LD A E +E++ + E A Sbjct: 947 DRETVIKELKKSLKIKGEELSEANVRLS---LLEKKLDSAAKDADERIEKVQTRLEETQA 1003 Query: 78 AERQREQYWEEKEQTL------LQFQKSKMACQLYREKVNALQ-----------AQVCEL 120 R++E+ +EE L L+ +K+++ +L + ++ V + Sbjct: 1004 LLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRGPPPSGIATLVSGI 1063 Query: 121 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 180 E Q + A + + KDS L Q+ +R + QLQ E +LK Sbjct: 1064 AGEEQQRGAIPGQAPGSVPGPGLVKDSPL-----LLQQISAMRLHISQLQHE-NSILKGA 1117 Query: 181 ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSR-ELVDSFRSSSP 239 + ++ P + + SQLL L+ S+ +VD R+S Sbjct: 1118 QMKASLASLPPLHVAKLSHEGPGSELPAGALYRKTSQLLETLNQLSTHTHVVDITRTSPA 1177 Query: 240 APPSQQSLYKRVAE 253 A L ++VA+ Sbjct: 1178 AKSPSAQLMEQVAQ 1191 Score = 30.0 bits (66), Expect = 4.3 Identities = 25/118 (21%), Positives = 55/118 (46%), Gaps = 3/118 (2%) Query: 8 ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67 EL+EQ +E + +R EK+R L ++ + + + + DE + + +E Sbjct: 425 ELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELE 484 Query: 68 IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125 + + A A R+ ++ E ++T+ +Q++ + YR+ LQ EL +++ Sbjct: 485 LREQLDMAGARVREAQKRVEAAQETVADYQQT---IKKYRQLTAHLQDVNRELTNQQE 539 >gi|88196790 coiled-coil domain containing 88 [Homo sapiens] Length = 1476 Score = 48.9 bits (115), Expect = 9e-06 Identities = 47/175 (26%), Positives = 82/175 (46%), Gaps = 20/175 (11%) Query: 10 QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIH 69 +E+ ++ Q +EEL RL+ E+++ + L LAE L + E +G R EL R+ Sbjct: 1141 RERLMQDGHRQRGLEEELRRLQSEHDRAQML---LAE---LSRERGELQGERGELRGRLA 1194 Query: 70 SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLY-------REKVNALQAQVCELQK 122 L E Q +Q E +Q L + C+L E+ L A+V L + Sbjct: 1195 RLELERAQLEMQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSR 1254 Query: 123 ER----DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEP 173 E +++ +RD RE + L + ++LRR+ +L +++ + Q R L+ P Sbjct: 1255 ENRELLERSLESRDHLHREQREYLDQLNALRREKQKLVEKIMD---QYRVLEPVP 1306 Score = 48.1 bits (113), Expect = 2e-05 Identities = 44/172 (25%), Positives = 81/172 (47%), Gaps = 13/172 (7%) Query: 8 ELQEQS---LRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQEL 64 EL+E++ L + ++ + + E+ RL++E + L ++L E G L Sbjct: 273 ELEEKAELLLDSQAEVQGLEAEIRRLRQEAQALSGQAKRAELYREEAEALRERAGRLPRL 332 Query: 65 VERIHSLRERAVAAERQREQYWEEKEQT-LLQFQKSKMACQLYREKVNALQAQVCELQKE 123 E + RER AAE + Q EE+ + +L+ K+ L E++ A + + L + Sbjct: 333 QEELRRCRERLQAAEAYKSQLEEERVLSGVLEASKA-----LLEEQLEAARERCARLHET 387 Query: 124 RDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPG 175 + + R + ++ E DSLR QV +L ++ EL +L++ PPG Sbjct: 388 QRENLLLRT----RLGEAHAELDSLRHQVDQLAEENVELELELQRSLEPPPG 435 Score = 33.5 bits (75), Expect = 0.39 Identities = 44/205 (21%), Positives = 84/205 (40%), Gaps = 18/205 (8%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKL-RSLTFSLAEKDILEQSLDEARGSRQEL 64 E + EQ+ R E+ +EL +E E L +L + E+ E+ R + Sbjct: 784 EAQAWEQA-RLREAVEAAGQELESASQEREALVEALAAAGRERRQWEREGSRLRAQSEAA 842 Query: 65 VERIHSL----RERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL 120 ER+ L R+ AER+R EKE + +K+ + + ++ LQ ++ + Sbjct: 843 EERMQVLESEGRQHLEEAERERR----EKEALQAELEKAVVRGKELGARLEHLQRELEQA 898 Query: 121 QKERDQAYSARDS--------AQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAE 172 ER + ++S QR ++ S + EL + +L +L QL+ Sbjct: 899 ALERQEFLREKESQHQRYQGLEQRLEAELQAAATSKEEALMELKTRALQLEEELFQLRQG 958 Query: 173 PPGVLKQEARTREPCPREKQRLVRM 197 P G+ ++ + + RL+ + Sbjct: 959 PAGLGPKKRAEPQLVETQNVRLIEV 983 Score = 32.3 bits (72), Expect = 0.86 Identities = 48/198 (24%), Positives = 83/198 (41%), Gaps = 11/198 (5%) Query: 6 ELELQEQSLRTASDQESGDEELN----RLKEENEKLRSLTFSLAEKDILEQSLDEARGSR 61 E L+ + A+ +E EL +L+EE +LR L K E L E + R Sbjct: 920 EQRLEAELQAAATSKEEALMELKTRALQLEEELFQLRQGPAGLGPKKRAEPQLVETQNVR 979 Query: 62 QELVERIHSLRERAVAAERQREQYWEEKEQTLL-QFQKSKMACQLYREKVNALQAQVCEL 120 VER +++ AA + + Q+ E + +L + Q+ + Q +E + LQA+ L Sbjct: 980 LIEVERSNAMLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSVL 1039 Query: 121 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGV---- 176 + + + + + + E+ + ++ R Q L L R+ +AE G+ Sbjct: 1040 EIQGQELHRKLEVLEEEVRAARQSQEETRGQQQALLRDHKALAQLQRRQEAELEGLLVRH 1099 Query: 177 --LKQEARTREPCPREKQ 192 LK R E RE Q Sbjct: 1100 RDLKANMRALELAHRELQ 1117 Score = 32.0 bits (71), Expect = 1.1 Identities = 54/241 (22%), Positives = 82/241 (34%), Gaps = 38/241 (15%) Query: 75 AVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSA 134 A A R+ Q EEK + LL Q + ++ +AQ Q +R + Y A Sbjct: 263 AKAQLRRLRQELEEKAELLLDSQAEVQGLEAEIRRLRQ-EAQALSGQAKRAELYREEAEA 321 Query: 135 QREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRL 194 RE + L R+ E ++QL + + + +A E ++R Sbjct: 322 LRERAGRLPRLQEELRRCRERLQAAEAYKSQLEEERVLSGVLEASKALLEEQLEAARERC 381 Query: 195 VRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPAPPSQQSLYKRVAED 254 R+H + E+ LL + EL DS R ++AE+ Sbjct: 382 ARLHE------------TQRENLLLRTRLGEAHAEL-DSLRHQ----------VDQLAEE 418 Query: 255 FGEEPWSFSSCLEIPEGDPGALPGAKAGDPHLDYELLDTADLPQLESSLQPVSPGRLDVS 314 E LE P G PG P A A P L+ ++ GRL Sbjct: 419 NVELELELQRSLEPPPGSPGEAPLAGAA--------------PSLQDEVREAEAGRLRTL 464 Query: 315 E 315 E Sbjct: 465 E 465 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 48.5 bits (114), Expect = 1e-05 Identities = 46/192 (23%), Positives = 92/192 (47%), Gaps = 12/192 (6%) Query: 6 ELELQEQSLRTASDQESGDEE----LNRLKEENEKLRS-LTFSLAEKDILEQSLDEAR-- 58 E +L E + S Q + +EE L +++ + E + S L L +++ Q L++A+ Sbjct: 1000 EKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRK 1059 Query: 59 --GSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQ 116 G +L ++I L+ + + Q + EE + L + + + V LQAQ Sbjct: 1060 LDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQ 1119 Query: 117 VCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVC---ELRTQLRQLQAEP 173 + ELQ++ + ++R+ A+++ E ++L+ ++ + D ELRT+ Q AE Sbjct: 1120 IAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAEL 1179 Query: 174 PGVLKQEARTRE 185 L++E + E Sbjct: 1180 KKALEEETKNHE 1191 Score = 46.2 bits (108), Expect = 6e-05 Identities = 46/194 (23%), Positives = 89/194 (45%), Gaps = 26/194 (13%) Query: 8 ELQEQSLRTASDQESGDEELNRLKE--ENEKLRSLTFSLAEKDI------LEQSLDEARG 59 E +E R A+ ++ +E L+ L+ E E+ R+ +K + LE+ LDE G Sbjct: 905 EAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEG 964 Query: 60 SRQEL-------VERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKV-- 110 +RQ+L +I + E + E Q ++ +EK+ L++ + ++ + QL E+ Sbjct: 965 ARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKK--LMEDRIAECSSQLAEEEEKA 1022 Query: 111 -------NALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELR 163 N + + +L++ + R ++ + E L+ Q+ EL Q+ EL+ Sbjct: 1023 KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELK 1082 Query: 164 TQLRQLQAEPPGVL 177 QL + + E G L Sbjct: 1083 LQLAKKEEELQGAL 1096 Score = 43.1 bits (100), Expect = 5e-04 Identities = 50/219 (22%), Positives = 95/219 (43%), Gaps = 40/219 (18%) Query: 12 QSLRTASDQESGDEELNRLKEENEKL--------RSLTFSLAEKDILEQSLDEARGSRQE 63 Q R + ++ DEEL ++KE+ K+ R L EK+IL + L + E Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQ----AETE 901 Query: 64 LVERIHSLRERAVAAERQREQYW---------EEKEQTLLQFQKSKMACQL--YREKVNA 112 L +R R A +++ E+ EE+ +LQ +K KM + E+++ Sbjct: 902 LFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDE 961 Query: 113 LQAQVCELQKERDQAYSARDSAQREI-------SQSLVEKDSLRRQVFELTDQVCE---- 161 + +LQ E+ A + + EI S+ + EK + ++ E + Q+ E Sbjct: 962 EEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEK 1021 Query: 162 ------LRTQLRQLQAEPPGVLKQEARTREPCPREKQRL 194 +R + + ++ LK+E +TR+ + K++L Sbjct: 1022 AKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKL 1060 Score = 38.1 bits (87), Expect = 0.016 Identities = 43/149 (28%), Positives = 68/149 (45%), Gaps = 11/149 (7%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65 +LE Q + L+ A QE ++ K L + L E+ LEQ E R + +LV Sbjct: 1789 QLERQNKELK-AKLQELEGAVKSKFKATISALEAKIGQLEEQ--LEQEAKE-RAAANKLV 1844 Query: 66 ERIHS-LRERAVAAERQR---EQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQ 121 R L+E + E +R +QY E+ E+ + ++ K + E+ A +LQ Sbjct: 1845 RRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQ 1904 Query: 122 KERDQAYSARDSAQREISQSLVEKDSLRR 150 +E D A A + RE+S K+ LRR Sbjct: 1905 RELDDATEANEGLSREVS---TLKNRLRR 1930 Score = 37.7 bits (86), Expect = 0.021 Identities = 44/182 (24%), Positives = 80/182 (43%), Gaps = 25/182 (13%) Query: 7 LELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVE 66 LE Q + +RT E ++EL E+ KLR A K E+ L + R + E + Sbjct: 1537 LEQQVEEMRT--QLEELEDELQAT--EDAKLRLEVNMQAMKAQFERDL-QTRDEQNEEKK 1591 Query: 67 RIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYR----------------EKV 110 R+ + R + AE + E+ K++ L K KM L +++ Sbjct: 1592 RLLIKQVRELEAELEDER----KQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQL 1647 Query: 111 NALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ 170 LQAQ+ + Q+E ++A ++RD + +S + SL ++ +L +++ R + Sbjct: 1648 RKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAE 1707 Query: 171 AE 172 E Sbjct: 1708 QE 1709 Score = 37.4 bits (85), Expect = 0.027 Identities = 68/278 (24%), Positives = 114/278 (41%), Gaps = 60/278 (21%) Query: 11 EQSLRTASDQESGD--EELNRLKEENEKLRSLTFSLAE-KDILEQSLDEARGSRQELVE- 66 E++ R ++++ D EEL LK E E T + E + EQ + E + + +E + Sbjct: 1130 EKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKN 1189 Query: 67 ---RIHSLRER-AVAAERQREQYWE--------EKEQTLLQFQKSKMACQL--------- 105 +I +R+R A A E EQ + EK + L+ ++AC++ Sbjct: 1190 HEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAE 1249 Query: 106 ---YREKVNA----LQAQVCE--------------LQKERDQAYSARDSAQREISQSLVE 144 R+K++A L A+V E LQ E D + + A+++ + + Sbjct: 1250 SEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKD 1309 Query: 145 KDSLRRQ-------VFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPR-EKQRLVR 196 SL Q + E T Q L +++RQL+ E + +Q+ E EKQ L Sbjct: 1310 AASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLAL 1369 Query: 197 MHAIC---PRDDSDCSLVSSTE---SQLLSDLSATSSR 228 + + D D + S E +LL D A S R Sbjct: 1370 QSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQR 1407 Score = 37.4 bits (85), Expect = 0.027 Identities = 31/151 (20%), Positives = 70/151 (46%), Gaps = 9/151 (5%) Query: 18 SDQESGDEELNRLKEENEKLRSLTFSL--AEKDILEQSLDEARGSRQELVERIHSLRERA 75 S + D +L+ +N++L++ L A K + ++ +L E++ + Sbjct: 1778 SAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKER 1837 Query: 76 VAAERQREQYWEEKEQTLLQFQKSKMACQLYRE---KVNA----LQAQVCELQKERDQAY 128 AA + + ++ ++ +Q + + Y+E K NA L+ Q+ E ++E +A Sbjct: 1838 AAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRAN 1897 Query: 129 SARDSAQREISQSLVEKDSLRRQVFELTDQV 159 ++R QRE+ + + L R+V L +++ Sbjct: 1898 ASRRKLQRELDDATEANEGLSREVSTLKNRL 1928 Score = 33.9 bits (76), Expect = 0.30 Identities = 46/199 (23%), Positives = 79/199 (39%), Gaps = 32/199 (16%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKL---RSLTFSLAEKDILEQS-------LD 55 +L +E+S+ +E E ++E + L R+L +L K+ E+ ++ Sbjct: 1455 QLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADME 1514 Query: 56 EARGSRQELVERIHSLRERAVAAERQREQ---YWEEKEQTL---------LQFQKSKMAC 103 + S+ ++ + +H L + A E+Q E+ EE E L L+ M Sbjct: 1515 DLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKA 1574 Query: 104 QLYR----------EKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVF 153 Q R EK L QV EL+ E + R A + ++ L Q+ Sbjct: 1575 QFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1634 Query: 154 ELTDQVCELRTQLRQLQAE 172 E+ QLR+LQA+ Sbjct: 1635 AANKARDEVIKQLRKLQAQ 1653 Score = 33.5 bits (75), Expect = 0.39 Identities = 41/193 (21%), Positives = 77/193 (39%), Gaps = 20/193 (10%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLA----EKDILEQSLDEARGSR 61 + ++++ + S DE + KE +KL+SL + E E++ A R Sbjct: 1651 QAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQER 1710 Query: 62 QELVERIHSL----------RERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVN 111 EL + I + + R A Q E+ EE++ + L + +N Sbjct: 1711 DELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLN 1770 Query: 112 ALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQA 171 A A ++ D A + +E+ L E + + F+ T + L ++ QL+ Sbjct: 1771 AELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKAT--ISALEAKIGQLEE 1828 Query: 172 EPPGVLKQEARTR 184 + L+QEA+ R Sbjct: 1829 Q----LEQEAKER 1837 Score = 32.7 bits (73), Expect = 0.66 Identities = 35/152 (23%), Positives = 71/152 (46%), Gaps = 7/152 (4%) Query: 25 EELNRLKEENEKLRSLTFSLAEKDIL----EQSLDEARGSRQELVERIHSLRERAVAAER 80 E+ ++L+ E + + +L +K I SL+ QEL++ R++ + R Sbjct: 1280 EKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQE--ETRQKLNLSSR 1337 Query: 81 QREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQ 140 R Q EEK Q ++ + A + ++V ALQ+Q+ + +K+ D +S + + Sbjct: 1338 IR-QLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKK 1396 Query: 141 SLVEKDSLRRQVFELTDQVCELRTQLRQLQAE 172 L + ++L +++ E +L +LQ E Sbjct: 1397 LLKDAEALSQRLEEKALAYDKLEKTKNRLQQE 1428 >gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] Length = 1417 Score = 48.5 bits (114), Expect = 1e-05 Identities = 46/216 (21%), Positives = 106/216 (49%), Gaps = 8/216 (3%) Query: 6 ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSL-AEKDILEQSLDEARGSRQEL 64 E +L+E+ + +S E L E+NEK+RSL ++ E + + + ++A+ E Sbjct: 703 EKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQ 762 Query: 65 VERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKER 124 + + ER A +++Q ++E+E+T+ Q+ + Q + E ++ L + E + E Sbjct: 763 HKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRL---LTESKGEM 819 Query: 125 DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVC--ELRTQLRQLQAEPPGVLKQ-EA 181 + +D A + + Q+ V +++++ + + ++C EL L QL+ KQ + Sbjct: 820 KKENMKKDEALKAL-QNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKK 878 Query: 182 RTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQ 217 ++ E +K+ ++ H++ + + L + + Q Sbjct: 879 KSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQ 914 Score = 40.4 bits (93), Expect = 0.003 Identities = 50/253 (19%), Positives = 105/253 (41%), Gaps = 24/253 (9%) Query: 25 EELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAAERQREQ 84 +EL +L+ E LT +L ++++LE L A G + + ++ LR+ A+ E+ Sbjct: 1042 KELEKLQHSTET--ELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEE 1099 Query: 85 YWEEKEQTLLQFQKSKMACQLYREKV----NALQAQVCELQKERDQAYSARDSAQRE--- 137 + + + ++ KM + ++++ AL+ + EL K+R + D RE Sbjct: 1100 KYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWEL-KQRAAQVTHLDMTIREHRG 1158 Query: 138 ------------ISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185 + +S +E +Q+ L D++ + QLR+ + ++ ++ ++ Sbjct: 1159 EMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKK 1218 Query: 186 PCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPAPPSQQ 245 R +QR+ M ++ + + L +L T RE V + + QQ Sbjct: 1219 EIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLT--REQVQNSHTELAEARHQQ 1276 Query: 246 SLYKRVAEDFGEE 258 +R E E Sbjct: 1277 VQAQREIERLSSE 1289 Score = 36.6 bits (83), Expect = 0.046 Identities = 46/228 (20%), Positives = 96/228 (42%), Gaps = 22/228 (9%) Query: 28 NRLKEENEKLRSLTFSLAE-KDILEQSLDEARGSRQELVERIHSLRERAVAAERQ----R 82 N++ EE K+R L +L K+ L L++ G++++ +++ E +++ Sbjct: 835 NQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKN 894 Query: 83 EQYWEEKEQT-LLQFQKSKMACQLYREKVN---------ALQAQVC----ELQKERDQAY 128 E EQ +LQ + L +E + L+ QV ELQK+R+ + Sbjct: 895 HSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSA 954 Query: 129 SARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCP 188 + + + E D R++V ELT +++ ++ Q + E + K+ + Sbjct: 955 EKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGE 1014 Query: 189 REKQRLVRMHAICPRDDSDCSLVSSTES-QLLSDLSATSSRELVDSFR 235 + L ++ I D + L T + + L L ++ EL ++ + Sbjct: 1015 NKAMHLSQLDMIL--DQTKTELEKKTNAVKELEKLQHSTETELTEALQ 1060 Score = 34.7 bits (78), Expect = 0.17 Identities = 39/177 (22%), Positives = 76/177 (42%), Gaps = 9/177 (5%) Query: 9 LQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERI 68 L+EQ + ++ + D+ L +E KL + EK EQSL E++ +L + Sbjct: 289 LEEQIINLEAEVSAQDKVL---REAENKLEQSQKMVIEK---EQSLQESKEECIKLKVDL 342 Query: 69 HSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAY 128 ++ AERQR + E+ FQ+ K + EK+ +QA+ L++ Sbjct: 343 LEQTKQGKRAERQRNEALYNAEELSKAFQQYK---KKVAEKLEKVQAEEEILERNLTNCE 399 Query: 129 SARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185 Q E + L+ ++ +L ++ + +LR + + V+ Q +R+ Sbjct: 400 KENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQ 456 >gi|78042577 MAP7 domain containing 1 [Homo sapiens] Length = 841 Score = 48.5 bits (114), Expect = 1e-05 Identities = 43/186 (23%), Positives = 89/186 (47%), Gaps = 17/186 (9%) Query: 9 LQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERI 68 L + R A +Q +E+ RL+ E +K + E+ + ++ EAR R+ R Sbjct: 602 LLAEKRRQAREQREREEQERRLQAERDK------RMREEQLAREA--EARAEREAEARRR 653 Query: 69 HS--LRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQ 126 RE+A A + ++E+ ++KE+ + ++ +L REK Q Q + +++R + Sbjct: 654 EEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLE 713 Query: 127 AYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREP 186 R + + E+S++ ++DS + + ++ ++A PG+ K+ + EP Sbjct: 714 EIMKR-TRKSEVSETKQKQDSKEANANGSSPE------PVKAVEARSPGLQKEAVQKEEP 766 Query: 187 CPREKQ 192 P+E Q Sbjct: 767 IPQEPQ 772 Score = 30.0 bits (66), Expect = 4.3 Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 10/110 (9%) Query: 87 EEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKD 146 + +E T L +K + A + RE+ + Q LQ ERD+ A+ +++ E + Sbjct: 595 DREEATRLLAEKRRQARE-QRER----EEQERRLQAERDKRMREEQLAREAEARAEREAE 649 Query: 147 SLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLVR 196 + RR+ E ++ + + +LQ + K+EA R E+QRL R Sbjct: 650 ARRREEQEAREKAQAEQEEQERLQKQ-----KEEAEARSREEAERQRLER 694 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.128 0.359 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,786,595 Number of Sequences: 37866 Number of extensions: 797405 Number of successful extensions: 6059 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 176 Number of HSP's successfully gapped in prelim test: 612 Number of HSP's that attempted gapping in prelim test: 3598 Number of HSP's gapped (non-prelim): 2219 length of query: 434 length of database: 18,247,518 effective HSP length: 105 effective length of query: 329 effective length of database: 14,271,588 effective search space: 4695352452 effective search space used: 4695352452 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.