Guide to the Human Genome
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Search of human proteins with 16507955

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16507955 caspase recruitment domain protein 14 isoform 2
[Homo sapiens]
         (434 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16507955 caspase recruitment domain protein 14 isoform 2 [Hom...   845   0.0  
gi|13129124 caspase recruitment domain protein 14 isoform 1 [Hom...   740   0.0  
gi|157743265 caspase recruitment domain family, member 11 [Homo ...   133   4e-31
gi|51093861 caspase recruitment domain protein 10 [Homo sapiens]      100   4e-21
gi|16554562 caspase recruitment domain protein 9 isoform 2 [Homo...    79   1e-14
gi|47717131 caspase recruitment domain protein 9 isoform 1 [Homo...    79   1e-14
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    57   4e-08
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    56   6e-08
gi|31982906 cingulin-like 1 [Homo sapiens]                             55   1e-07
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    54   2e-07
gi|46852390 coiled-coil domain containing 6 [Homo sapiens]             54   2e-07
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         54   3e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    52   1e-06
gi|21735548 centrosomal protein 2 [Homo sapiens]                       51   2e-06
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa...    51   2e-06
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                51   2e-06
gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]              51   2e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    50   3e-06
gi|4506467 radixin [Homo sapiens]                                      50   3e-06
gi|219521893 coiled-coil transcriptional coactivator isoform 2 [...    50   3e-06
gi|148746195 trichohyalin [Homo sapiens]                               50   5e-06
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...    50   5e-06
gi|205277396 dynactin 1 isoform 4 [Homo sapiens]                       49   7e-06
gi|205277392 dynactin 1 isoform 3 [Homo sapiens]                       49   7e-06
gi|13259508 dynactin 1 isoform 2 [Homo sapiens]                        49   7e-06
gi|13259510 dynactin 1 isoform 1 [Homo sapiens]                        49   7e-06
gi|88196790 coiled-coil domain containing 88 [Homo sapiens]            49   9e-06
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    49   1e-05
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   49   1e-05
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    49   1e-05

>gi|16507955 caspase recruitment domain protein 14 isoform 2 [Homo
           sapiens]
          Length = 434

 Score =  845 bits (2183), Expect = 0.0
 Identities = 434/434 (100%), Positives = 434/434 (100%)

Query: 1   MVSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGS 60
           MVSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGS
Sbjct: 1   MVSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGS 60

Query: 61  RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL 120
           RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL
Sbjct: 61  RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL 120

Query: 121 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 180
           QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE
Sbjct: 121 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 180

Query: 181 ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPA 240
           ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPA
Sbjct: 181 ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPA 240

Query: 241 PPSQQSLYKRVAEDFGEEPWSFSSCLEIPEGDPGALPGAKAGDPHLDYELLDTADLPQLE 300
           PPSQQSLYKRVAEDFGEEPWSFSSCLEIPEGDPGALPGAKAGDPHLDYELLDTADLPQLE
Sbjct: 241 PPSQQSLYKRVAEDFGEEPWSFSSCLEIPEGDPGALPGAKAGDPHLDYELLDTADLPQLE 300

Query: 301 SSLQPVSPGRLDVSESGVLMRRRPARRILSQVTMLAFQGDALLEQISVIGGNLTGIFIHR 360
           SSLQPVSPGRLDVSESGVLMRRRPARRILSQVTMLAFQGDALLEQISVIGGNLTGIFIHR
Sbjct: 301 SSLQPVSPGRLDVSESGVLMRRRPARRILSQVTMLAFQGDALLEQISVIGGNLTGIFIHR 360

Query: 361 VTPGSAADQMALRPGTQIVMVSRARPLLSPGLLMGTVAAGGVTQADFTSPRRCRSTLGWA 420
           VTPGSAADQMALRPGTQIVMVSRARPLLSPGLLMGTVAAGGVTQADFTSPRRCRSTLGWA
Sbjct: 361 VTPGSAADQMALRPGTQIVMVSRARPLLSPGLLMGTVAAGGVTQADFTSPRRCRSTLGWA 420

Query: 421 SALSWADVKRSAHL 434
           SALSWADVKRSAHL
Sbjct: 421 SALSWADVKRSAHL 434


>gi|13129124 caspase recruitment domain protein 14 isoform 1 [Homo
           sapiens]
          Length = 1004

 Score =  740 bits (1910), Expect = 0.0
 Identities = 381/381 (100%), Positives = 381/381 (100%)

Query: 1   MVSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGS 60
           MVSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGS
Sbjct: 238 MVSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGS 297

Query: 61  RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL 120
           RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL
Sbjct: 298 RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL 357

Query: 121 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 180
           QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE
Sbjct: 358 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 417

Query: 181 ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPA 240
           ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPA
Sbjct: 418 ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPA 477

Query: 241 PPSQQSLYKRVAEDFGEEPWSFSSCLEIPEGDPGALPGAKAGDPHLDYELLDTADLPQLE 300
           PPSQQSLYKRVAEDFGEEPWSFSSCLEIPEGDPGALPGAKAGDPHLDYELLDTADLPQLE
Sbjct: 478 PPSQQSLYKRVAEDFGEEPWSFSSCLEIPEGDPGALPGAKAGDPHLDYELLDTADLPQLE 537

Query: 301 SSLQPVSPGRLDVSESGVLMRRRPARRILSQVTMLAFQGDALLEQISVIGGNLTGIFIHR 360
           SSLQPVSPGRLDVSESGVLMRRRPARRILSQVTMLAFQGDALLEQISVIGGNLTGIFIHR
Sbjct: 538 SSLQPVSPGRLDVSESGVLMRRRPARRILSQVTMLAFQGDALLEQISVIGGNLTGIFIHR 597

Query: 361 VTPGSAADQMALRPGTQIVMV 381
           VTPGSAADQMALRPGTQIVMV
Sbjct: 598 VTPGSAADQMALRPGTQIVMV 618


>gi|157743265 caspase recruitment domain family, member 11 [Homo
           sapiens]
          Length = 1154

 Score =  133 bits (334), Expect = 4e-31
 Identities = 124/484 (25%), Positives = 202/484 (41%), Gaps = 110/484 (22%)

Query: 1   MVSSCELELQEQSLRTASDQESGD--EELNRLKEENEKLRSLTFSL-------------- 44
           M   C+LE + QSL+  +D E+    E++  L+ ENE L++    L              
Sbjct: 239 MEEECKLE-RNQSLKLKNDIENRPKKEQVLELERENEMLKTKNQELQSIIQAGKRSLPDS 297

Query: 45  --AEKDILEQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMA 102
             A  DILE    EA   RQELV RI++L+E A  AE  R++Y EEKE   L+       
Sbjct: 298 DKAILDILEHDRKEALEDRQELVNRIYNLQEEARQAEELRDKYLEEKEDLELKCSTLGKD 357

Query: 103 CQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQ---- 158
           C++Y+ ++N +  Q+ E+++ERDQA+ +RD AQ + SQ L+EKD  R+Q+ EL ++    
Sbjct: 358 CEMYKHRMNTVMLQLEEVERERDQAFHSRDEAQTQYSQCLIEKDKYRKQIRELEEKNDEM 417

Query: 159 ----------VCELRTQLRQLQAE------------PPGVLKQ---------------EA 181
                     +  L ++LR+L  +            P  ++ Q               ++
Sbjct: 418 RIEMVRREACIVNLESKLRRLSKDSNNLDQSLPRNLPVTIISQDFGDASPRTNGQEADDS 477

Query: 182 RTREPCPREKQRLVRMH------------------AICPRDDSDCSLVSSTESQLLSDLS 223
            T E  P + +  +  H                   I  +  SD       E    +  S
Sbjct: 478 STSEESPEDSKYFLPYHPPQRRMNLKGIQLQRAKSPISLKRTSDFQAKGHEEEGTDASPS 537

Query: 224 ATSSRELVDSFRSSSP------------APPSQQSLYKRVAEDFGEEPWSFSSCLEIPEG 271
           +  S  + +SF    P             PP   S+ +R  ED         S +E  + 
Sbjct: 538 SCGSLPITNSFTKMQPPRSRSSIMSITAEPPGNDSIVRRYKEDAPHR-----STVE-EDN 591

Query: 272 DPGALPGAKAGDPHLDYELLDTADLPQLESSLQPVSPGRLDVSESGVLMRR----RPARR 327
           D G        D   +      + +    SS Q       D+ +  ++ R+    RP R 
Sbjct: 592 DSGGFDALDLDDDSHERYSFGPSSIHSSSSSHQSEGLDAYDLEQVNLMFRKFSLERPFRP 651

Query: 328 ILSQVTML----------AFQGDALLEQISVIGGNLTGIFIHRVTPGSAADQMALRPGTQ 377
            ++ V  +             GD+L  Q++++GGN  G F+H V PGS A++  LR G Q
Sbjct: 652 SVTSVGHVRGPGPSVQHTTLNGDSLTSQLTLLGGNARGSFVHSVKPGSLAEKAGLREGHQ 711

Query: 378 IVMV 381
           ++++
Sbjct: 712 LLLL 715



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 39/198 (19%), Positives = 88/198 (44%), Gaps = 16/198 (8%)

Query: 7   LELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVE 66
           L  QE+  +   +++S ++EL ++K++N  L      L+E+     ++  +R  + E+ +
Sbjct: 174 LTFQERYYKMKEERDSYNDELVKVKDDNYNLAMRYAQLSEEK--NMAVMRSRDLQLEIDQ 231

Query: 67  RIHSLRERAVAAERQREQYWE---------EKEQTLLQFQKSKMACQLYREKVNALQAQV 117
             H L +     + +R Q  +         +KEQ L   ++++M     +E  + +QA  
Sbjct: 232 LKHRLNKMEEECKLERNQSLKLKNDIENRPKKEQVLELERENEMLKTKNQELQSIIQAGK 291

Query: 118 CELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVL 177
             L    D   +  D  + +  ++L ++  L  +++ L ++  +   +LR    E    L
Sbjct: 292 RSLP---DSDKAILDILEHDRKEALEDRQELVNRIYNLQEEARQAE-ELRDKYLEEKEDL 347

Query: 178 KQEART-REPCPREKQRL 194
           + +  T  + C   K R+
Sbjct: 348 ELKCSTLGKDCEMYKHRM 365


>gi|51093861 caspase recruitment domain protein 10 [Homo sapiens]
          Length = 1032

 Score = 99.8 bits (247), Expect = 4e-21
 Identities = 78/237 (32%), Positives = 117/237 (49%), Gaps = 18/237 (7%)

Query: 48  DILEQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYR 107
           DILE    EA+ SRQEL +++H+++     AE  R+QY +E E   L+ +  +  C LY+
Sbjct: 319 DILEHDWREAQDSRQELCQKLHAVQGELQWAEELRDQYLQEMEDLRLKHRTLQKDCDLYK 378

Query: 108 EKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLR 167
            ++  + AQ+ E++KERDQA  +RD  Q + SQSL+EKD  R+QV  L  +  EL T L 
Sbjct: 379 HRMATVLAQLEEIEKERDQAIQSRDRIQLQYSQSLIEKDQYRKQVRGLEAERDELLTTLT 438

Query: 168 QLQAEPPGVLKQEARTREPCPREKQRLVRMHAICPRDDSDCSL----------VSSTESQ 217
            L  E    L +    R       +     H++C    S  SL           ++ E+ 
Sbjct: 439 SL--EGTKALLEVQLQRAQGGTCLKACASSHSLCSNLSSTWSLSEFPSPLGGPEATGEAA 496

Query: 218 LLSDLSATSSRELVDSFR-----SSSPAPPSQQSLYKRVAEDFGEEP-WSFSSCLEI 268
           ++      +S E  DS +     S  P PPS  S+ +R  E+    P  SFSS  +I
Sbjct: 497 VMGGPEPHNSEEATDSEKEINRLSILPFPPSAGSILRRQREEDPAPPKRSFSSMSDI 553


>gi|16554562 caspase recruitment domain protein 9 isoform 2 [Homo
           sapiens]
          Length = 492

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 68/234 (29%), Positives = 111/234 (47%), Gaps = 23/234 (9%)

Query: 5   CELELQEQ-SLRTASDQESGDEELNRLKEENEKLRSLTFSLAEK-------------DIL 50
           C++E +    LR A +Q    E L  L++E   L++    L                 +L
Sbjct: 224 CKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVL 283

Query: 51  EQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKV 110
           E+   +A    QE    I SLR+     E +R +  EEKE   LQ    +   ++Y++++
Sbjct: 284 EEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRI 343

Query: 111 NALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ 170
            A+  Q+ E+  ERDQA + R+    + ++ L EKD+LR+QV EL ++  EL+ Q+ Q +
Sbjct: 344 EAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCE 403

Query: 171 AEPPGVLKQEARTREPCPREKQRLVRMHAI---CPRDDSDCSLVSSTESQLLSD 221
           A+   +L  E R R    ++ + LV    +    PR   + SL    E   LSD
Sbjct: 404 AQ---LLAVEGRLRR---QQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSD 451



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 37/133 (27%), Positives = 62/133 (46%), Gaps = 15/133 (11%)

Query: 10  QEQSLRTASDQESGDEELNRLKEENEKL-RSLTFSLAEKDI-------LEQSLDEARGSR 61
           QE+  R   + E+G  EL R KEEN  L   L     EK         L+  +D+ + S 
Sbjct: 158 QERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSL 217

Query: 62  QEL-----VERIHSLRERAVAAER-QREQYWE-EKEQTLLQFQKSKMACQLYREKVNALQ 114
            +      VER H+L+ R    +R  +E  WE ++E+ LLQ +  ++   +   K++   
Sbjct: 218 MKAEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSS 277

Query: 115 AQVCELQKERDQA 127
             +  L+++  QA
Sbjct: 278 PYIQVLEEDWRQA 290



 Score = 29.6 bits (65), Expect = 5.6
 Identities = 35/160 (21%), Positives = 72/160 (45%), Gaps = 14/160 (8%)

Query: 21  ESGDEEL--NRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAA 78
           ESG  +L    + +  +K++ LT  L+ KD   + L       ++  ER+  L+E   A 
Sbjct: 112 ESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAG 171

Query: 79  ERQREQYWEEKEQTLLQF--QKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQR 136
            R+ ++  EE     ++   Q  +    L R +   LQ ++ +L   +     A D  + 
Sbjct: 172 SRELKRCKEENYDLAMRLAHQSEEKGAALMRNR--DLQLEIDQL---KHSLMKAEDDCKV 226

Query: 137 EISQSL-----VEKDSLRRQVFELTDQVCELRTQLRQLQA 171
           E   +L     +E+   +  ++EL  +   L+ ++++L+A
Sbjct: 227 ERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEA 266


>gi|47717131 caspase recruitment domain protein 9 isoform 1 [Homo
           sapiens]
          Length = 536

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 68/234 (29%), Positives = 111/234 (47%), Gaps = 23/234 (9%)

Query: 5   CELELQEQ-SLRTASDQESGDEELNRLKEENEKLRSLTFSLAEK-------------DIL 50
           C++E +    LR A +Q    E L  L++E   L++    L                 +L
Sbjct: 224 CKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSSPYIQVL 283

Query: 51  EQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKV 110
           E+   +A    QE    I SLR+     E +R +  EEKE   LQ    +   ++Y++++
Sbjct: 284 EEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRKDSKMYKDRI 343

Query: 111 NALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ 170
            A+  Q+ E+  ERDQA + R+    + ++ L EKD+LR+QV EL ++  EL+ Q+ Q +
Sbjct: 344 EAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKADELQLQVFQCE 403

Query: 171 AEPPGVLKQEARTREPCPREKQRLVRMHAI---CPRDDSDCSLVSSTESQLLSD 221
           A+   +L  E R R    ++ + LV    +    PR   + SL    E   LSD
Sbjct: 404 AQ---LLAVEGRLRR---QQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLSD 451



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 37/133 (27%), Positives = 62/133 (46%), Gaps = 15/133 (11%)

Query: 10  QEQSLRTASDQESGDEELNRLKEENEKL-RSLTFSLAEKDI-------LEQSLDEARGSR 61
           QE+  R   + E+G  EL R KEEN  L   L     EK         L+  +D+ + S 
Sbjct: 158 QERVQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSL 217

Query: 62  QEL-----VERIHSLRERAVAAER-QREQYWE-EKEQTLLQFQKSKMACQLYREKVNALQ 114
            +      VER H+L+ R    +R  +E  WE ++E+ LLQ +  ++   +   K++   
Sbjct: 218 MKAEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRSS 277

Query: 115 AQVCELQKERDQA 127
             +  L+++  QA
Sbjct: 278 PYIQVLEEDWRQA 290



 Score = 29.6 bits (65), Expect = 5.6
 Identities = 35/160 (21%), Positives = 72/160 (45%), Gaps = 14/160 (8%)

Query: 21  ESGDEEL--NRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAA 78
           ESG  +L    + +  +K++ LT  L+ KD   + L       ++  ER+  L+E   A 
Sbjct: 112 ESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECEAG 171

Query: 79  ERQREQYWEEKEQTLLQF--QKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQR 136
            R+ ++  EE     ++   Q  +    L R +   LQ ++ +L   +     A D  + 
Sbjct: 172 SRELKRCKEENYDLAMRLAHQSEEKGAALMRNR--DLQLEIDQL---KHSLMKAEDDCKV 226

Query: 137 EISQSL-----VEKDSLRRQVFELTDQVCELRTQLRQLQA 171
           E   +L     +E+   +  ++EL  +   L+ ++++L+A
Sbjct: 227 ERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEA 266


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 39/180 (21%), Positives = 86/180 (47%), Gaps = 2/180 (1%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
           ++  QE+ +R   +Q    EE   LK++ +  +       E+ + EQ  ++ R   +++ 
Sbjct: 256 QMRKQEEQMREQEEQMREQEE-QMLKQKEQTEQEEQTGEQEEQMREQE-EQMREQEEQMR 313

Query: 66  ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125
           E+   +RE+     +Q EQ WE+KEQ   Q ++     +   E+   +Q Q  +++K+ +
Sbjct: 314 EQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEE 373

Query: 126 QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185
           Q     +  +++  Q   +++ +  Q  ++ +Q  ++R Q  Q+  +   + KQE    E
Sbjct: 374 QMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGE 433



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 37/181 (20%), Positives = 88/181 (48%), Gaps = 2/181 (1%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDE-ARGSRQEL 64
           E ++ EQ  +    +E   ++  ++ E+ E++R     + E++   Q  +E  +   +++
Sbjct: 198 EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQM 257

Query: 65  VERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKER 124
            ++   +RE+      Q EQ  ++KEQT  + Q  +   Q+ RE+   ++ Q  +++++ 
Sbjct: 258 RKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQM-REQEEQMREQEEQMREQE 316

Query: 125 DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTR 184
           +Q     +   ++  Q   +K+ +  Q  ++  Q  ++  Q  Q+Q +   V KQE + R
Sbjct: 317 EQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMR 376

Query: 185 E 185
           +
Sbjct: 377 K 377



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 45/196 (22%), Positives = 95/196 (48%), Gaps = 8/196 (4%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQE-- 63
           E ++ EQ  +    +E   ++  +++++ E++R     + E++  EQ L +   + QE  
Sbjct: 233 EEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQE--EQMLKQKEQTEQEEQ 290

Query: 64  LVERIHSLRERAVAAERQREQYWEEKEQTLLQ-FQKSKMACQLYREKVNALQAQVCELQK 122
             E+   +RE+      Q EQ  E++EQ   Q  Q  K   Q++ +K   +  Q  ++ K
Sbjct: 291 TGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQK-EQMWEQKEQMWK 349

Query: 123 ERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQL--QAEPPGVLKQE 180
           + +Q     +  Q++  Q   +++ +R+Q  ++  Q  ++R Q  Q+  Q E  G  K++
Sbjct: 350 QEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQ 409

Query: 181 ARTREPCPREKQRLVR 196
            R +E    E++  +R
Sbjct: 410 MREQEEQMGEQKEQMR 425



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 36/183 (19%), Positives = 91/183 (49%), Gaps = 6/183 (3%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
           +++ QE+ +R   +Q    EE  +++E+ E++        +++   +  ++ R   +++ 
Sbjct: 249 QVQKQEEQMRKQEEQMREQEE--QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306

Query: 66  ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125
           E+   +RE+      Q EQ  +++EQ   Q ++     +   ++   +  Q  ++QK+ +
Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEE 366

Query: 126 QAYSARDSAQREISQSLVEKDSLRR---QVFELTDQVCELRTQLRQLQAEPPGVLKQEAR 182
           Q     +  +++  Q   +++ +R+   Q+ E  +Q+ E + Q+R+ Q E  G  K++ R
Sbjct: 367 QVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMRE-QEEQMGEQKEQMR 425

Query: 183 TRE 185
            +E
Sbjct: 426 KQE 428



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 34/176 (19%), Positives = 86/176 (48%), Gaps = 2/176 (1%)

Query: 10  QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIH 69
           QE+ +R   +Q    EE  + +EE  + +       E+ + EQ  ++ R   ++++++  
Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQE-EQMREQEEQMLKQKE 283

Query: 70  SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYS 129
              +     E Q EQ  E++EQ   Q ++ +   +  RE+   +  Q  ++ ++++Q + 
Sbjct: 284 QTEQEEQTGE-QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342

Query: 130 ARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185
            ++   ++  Q   +++ +++Q  ++  Q  ++R Q  Q++ +   + KQE +  E
Sbjct: 343 QKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE 398



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 36/182 (19%), Positives = 86/182 (47%), Gaps = 7/182 (3%)

Query: 10  QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIH 69
           QE+ ++   +Q    EE  R +EE    +       E+ + +Q  ++ R   +++ E+  
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQE-EQMRKQEEQMREQEE 269

Query: 70  SLRERAVAAERQREQY------WEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE 123
            +RE+     +Q+EQ        E++EQ   Q ++ +   +  RE+   ++ Q  ++ K+
Sbjct: 270 QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ 329

Query: 124 RDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEART 183
            +Q +  ++    +  Q   +++ +  Q  ++  Q  ++R Q  Q++ +   + KQE + 
Sbjct: 330 EEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQM 389

Query: 184 RE 185
           R+
Sbjct: 390 RK 391



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 37/194 (19%), Positives = 92/194 (47%), Gaps = 4/194 (2%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKD--ILEQSLDEARGSRQE 63
           E +++EQ  +    +    E+  +++E+  ++R     + E++  + EQ   + R    +
Sbjct: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE-GQVREQEGQ 179

Query: 64  LVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE 123
           + E+   +RE+      Q  Q  E++EQ   Q ++ +   +   E+   ++ Q  ++ ++
Sbjct: 180 VREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQ 239

Query: 124 RDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQL-QAEPPGVLKQEAR 182
            +Q     +  Q++  Q   +++ +R Q  ++ +Q  ++  Q  Q  Q E  G  +++ R
Sbjct: 240 EEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMR 299

Query: 183 TREPCPREKQRLVR 196
            +E   RE++  +R
Sbjct: 300 EQEEQMREQEEQMR 313



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 35/182 (19%), Positives = 86/182 (47%), Gaps = 3/182 (1%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKD--ILEQSLDEARGSRQE 63
           E +++EQ  +    +    E+  +++E+  ++R     + E++  + EQ   + R    +
Sbjct: 86  EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE-GQVREQEGQ 144

Query: 64  LVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE 123
           + E+   +RE+      Q  Q  E++ Q   Q  + +      RE+   +  Q  ++ ++
Sbjct: 145 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQ 204

Query: 124 RDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEART 183
            +Q     +  Q++  Q   +++ +R+Q  ++ +Q  +++ Q  Q+Q +   + KQE + 
Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264

Query: 184 RE 185
           RE
Sbjct: 265 RE 266


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 43/204 (21%), Positives = 101/204 (49%), Gaps = 17/204 (8%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
           E  L+EQ  +    +E    +  RL+E+ ++LR     L E+  L +  ++ +   +++ 
Sbjct: 299 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMW 358

Query: 66  ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYR-----EKVNALQAQVCEL 120
           E+   +RE+     RQ E+ WE+++Q  ++ Q+ KM  Q  R     E++   + ++ E 
Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQ--MREQEQKMRDQEERMWEQDERLREKEERMREQ 416

Query: 121 QKERDQAYSARDSAQ--------REISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAE 172
           +K  +Q    R+  +        R+  + + E++ +R +  ++ ++   +R Q  ++Q +
Sbjct: 417 EKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 476

Query: 173 PPGVLKQEAR--TREPCPREKQRL 194
              + +QE +   ++  P +K++L
Sbjct: 477 EENMWEQEEKEWQQQRLPEQKEKL 500



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 53/196 (27%), Positives = 97/196 (49%), Gaps = 18/196 (9%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSL--AEKDILEQSLDEARGSRQE 63
           E EL+EQ  +    +E    +  RL+E+  K+R     +   EK + EQ   E R   +E
Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQE-KELREQEKE 336

Query: 64  LVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE 123
           L E+   LRE+    + Q E+ WE++E+  ++ Q+ KM  Q         + ++ E +K+
Sbjct: 337 LREQ-KELREQEEQMQEQEEKMWEQEEK--MREQEEKMWRQ---------EERLWEQEKQ 384

Query: 124 -RDQAYSARDSAQR--EISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 180
            R+Q    RD  +R  E  + L EK+   R+  ++ +QV ++R + +  + E     ++E
Sbjct: 385 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE 444

Query: 181 ARTREPCPREKQRLVR 196
               E   RE+++ +R
Sbjct: 445 KMQEEERIREREKKMR 460



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 45/201 (22%), Positives = 96/201 (47%), Gaps = 22/201 (10%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQE-- 63
           E ++QEQ  +T  DQE   +E  R++E  +K+R    ++ E++   Q  +E    ++E  
Sbjct: 429 EKKMQEQEKKTR-DQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 487

Query: 64  -LVERIHSLRERAVAAER---QREQYWEEKEQTLLQFQKSKMACQLYR-EKVNALQAQVC 118
              +R+   +E+    E+   Q E+ WE++E+   Q +      +++R EK+   + Q+ 
Sbjct: 488 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 547

Query: 119 EL-QKERDQAYSARDSAQR-------------EISQSLVEKDSLRRQVFELTDQVCELRT 164
           E  +K RDQ     D  +R             +  + + E++ +R +  ++ ++   +R 
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 607

Query: 165 QLRQLQAEPPGVLKQEARTRE 185
           Q  ++Q +   + +QE +  E
Sbjct: 608 QEEKMQEQEEKMQEQEEKMWE 628



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 48/191 (25%), Positives = 96/191 (50%), Gaps = 21/191 (10%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
           ELQE+     ++ E  + +LN +KE   KL    F L +  +   +L E    ++E    
Sbjct: 229 ELQEKL--PLAESEKSEIQLN-VKELKRKLERAKFLLPQ--VQTNTLQEEMWRQEE---- 279

Query: 68  IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE-RDQ 126
              LRE+     +Q E+ W ++E+  L+ Q+ KM  Q   EK+   + ++ E +KE R+Q
Sbjct: 280 --ELREQEKKIRKQEEKMWRQEER--LREQEGKMREQ--EEKMWRQEKRLREQEKELREQ 333

Query: 127 AYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREP 186
               R+  Q+E+ +   +++ ++ Q  ++ +Q  ++R Q  ++  +   + +QE + RE 
Sbjct: 334 EKELRE--QKELRE---QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 388

Query: 187 CPREKQRLVRM 197
             + + +  RM
Sbjct: 389 EQKMRDQEERM 399



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 41/200 (20%), Positives = 97/200 (48%), Gaps = 16/200 (8%)

Query: 7   LELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVE 66
           L  +E+ +R   +QE   E++ +++EE +K++       +++   Q  +  R   +++ E
Sbjct: 406 LREKEERMR---EQEKMWEQVEKMREE-KKMQEQEKKTRDQEEKMQEEERIREREKKMRE 461

Query: 67  RIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLY-REKVNALQAQVCEL-QKER 124
              ++RE+    ++Q E  WE++E+   Q +  +   +L+ +EK+   + ++ E  +K R
Sbjct: 462 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 521

Query: 125 DQAYS--------ARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGV 176
           DQ            ++  + +  Q   +++ +R Q  ++ DQ  E R + +  + E    
Sbjct: 522 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ--EERMEKKTQEQEKKTW 579

Query: 177 LKQEARTREPCPREKQRLVR 196
            ++E    E   RE+++ +R
Sbjct: 580 DQEEKMREEERMREREKKMR 599



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 37/189 (19%), Positives = 88/189 (46%), Gaps = 19/189 (10%)

Query: 9   LQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERI 68
           ++EQ  +    +E   E+  ++ E+ EK++     + E++      +E    +Q L E+ 
Sbjct: 605 MREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQK 664

Query: 69  HSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKER-DQA 127
             L E     E+++ Q  EEK      +++ KM      +K    + +  + +K R +++
Sbjct: 665 EKLWEHEKMQEQEKMQEQEEK-----IWEQEKM-----EKKTQEQEKKTWDQEKMREEES 714

Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEAR--TRE 185
              R+   RE      E++ +R Q  ++ +Q  +++ Q  ++  +   + +QE +   ++
Sbjct: 715 MREREKKMRE------EEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQ 768

Query: 186 PCPREKQRL 194
             P +K++L
Sbjct: 769 RLPEQKEKL 777



 Score = 36.2 bits (82), Expect = 0.060
 Identities = 32/190 (16%), Positives = 83/190 (43%), Gaps = 5/190 (2%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
           +++ QE+ +      E   +E  +   + EK+R        +  + +  +  R   +++ 
Sbjct: 678 KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQ 737

Query: 66  ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL-QKER 124
           E+   ++E+      Q E+ WE++E+   Q +  +   +L+  +    Q ++ E  +K R
Sbjct: 738 EQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMR 797

Query: 125 DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTR 184
           DQ    R   ++   Q    ++ +R Q  ++  Q  ++  Q  ++  +   +  QE +  
Sbjct: 798 DQEEKMRGQEEKMRGQ----EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKME 853

Query: 185 EPCPREKQRL 194
           E    +++++
Sbjct: 854 EKMQGQEEKM 863



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 24/154 (15%), Positives = 72/154 (46%), Gaps = 4/154 (2%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
           ++QEQ  +    +E   ++     +E +  R       E  + EQ  ++ R   Q++ ++
Sbjct: 505 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE-EKMRDQEQKMWDQ 563

Query: 68  IHSLRERAVAAERQ---REQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKER 124
              + ++    E++   +E+   E+E+   + +K +   ++ RE+   +Q Q  ++Q++ 
Sbjct: 564 EERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 623

Query: 125 DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQ 158
           ++ +   +  Q +  +   +++ +  Q  ++ +Q
Sbjct: 624 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 657


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 44/210 (20%), Positives = 96/210 (45%), Gaps = 10/210 (4%)

Query: 10   QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIH 69
            Q+Q      ++    E+L RLK E E  R       EK + ++  D    SR   +E  +
Sbjct: 915  QKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEK-LQKEMADIVEASRTSTLELQN 973

Query: 70   SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYS 129
             L E      R+  +   + ++  L+ +KS++     ++++  ++ ++ + Q+ +D+A +
Sbjct: 974  QLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALT 1033

Query: 130  ARDSAQREISQSLVE-------KDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEAR 182
             R   ++ +     E       KD   R V ++ D+V +L  +L + +     + ++ +R
Sbjct: 1034 KRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISR 1093

Query: 183  TREPCPREKQRLVRMHAICPRDDSDCSLVS 212
            +RE   + +  L++  A   R D +C  +S
Sbjct: 1094 SREQMEQLRNELLQERA--ARQDLECDKIS 1121



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 53/218 (24%), Positives = 100/218 (45%), Gaps = 43/218 (19%)

Query: 8   ELQEQSLRTASDQE--SGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
           E +  +L+ A  +E  S D+E+++LKE+ +         AE   L +S++EA  + + L 
Sbjct: 757 ERELTALKGALKEEVSSHDQEMDKLKEQYD---------AELQALRESVEEATKNVEVLA 807

Query: 66  ERIHS---------LRERAVAAERQREQ-YWEEKEQTLLQFQ-----------KSKMACQ 104
            R ++         +R + +  E ++ Q   EE E+ + Q Q           K+K   +
Sbjct: 808 SRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLK 867

Query: 105 LYREKVNALQAQVCELQKERDQAYSAR-------DSAQREISQSLVEKDSLRRQVFELTD 157
            Y  ++  L+  +   +KE  +A SAR       ++AQ  +SQ+  E+  L  ++ E ++
Sbjct: 868 KYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESE 927

Query: 158 QVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLV 195
           Q    + QLR+L+ E         +T E   +E   +V
Sbjct: 928 Q----KEQLRRLKNEMENERWHLGKTIEKLQKEMADIV 961



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 44/180 (24%), Positives = 79/180 (43%), Gaps = 31/180 (17%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSL-TFSLAEKDILEQSLDEARGSRQELVE 66
           ELQ Q      +Q++  EE  R++   E+LRS     + E   L+Q L+E+ G  ++ +E
Sbjct: 625 ELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLE 684

Query: 67  RIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQ 126
            +  ++        +REQ+  E                     +  LQ Q+ E+  E D 
Sbjct: 685 ELFQVK-------MEREQHQTE---------------------IRDLQDQLSEMHDELDS 716

Query: 127 AYSARDSAQREISQSLVE-KDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185
           A  + D  +  + + L++ K  L+  +    +Q   LR + R+L A   G LK+E  + +
Sbjct: 717 AKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTA-LKGALKEEVSSHD 775


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 40/191 (20%), Positives = 94/191 (49%), Gaps = 11/191 (5%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
           E  L+EQ  +    +E    +  RL+E+ ++LR     L E+  L +  ++ +   +++ 
Sbjct: 261 EERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMW 320

Query: 66  ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125
           E+   +RE+     RQ E+ WE+++Q   Q QK +   +   E+   L+ +  E  +E++
Sbjct: 321 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE-ERMREQE 379

Query: 126 QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEAR--T 183
           + +   +  Q        E++ +R +  ++ ++   +R Q  ++Q +   + +QE +   
Sbjct: 380 KMWEQEEKMQ--------EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ 431

Query: 184 REPCPREKQRL 194
           ++  P +K++L
Sbjct: 432 QQRLPEQKEKL 442



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 53/224 (23%), Positives = 103/224 (45%), Gaps = 12/224 (5%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
           E  ++E+  +   ++E   E+  +++E+ EK+R     + E++   Q  +E    ++E +
Sbjct: 559 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 618

Query: 66  ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125
                 +E     + Q E  WE++E+  +Q Q+ KM  Q   EK+   + ++ E Q+E+ 
Sbjct: 619 WE----QEEEDKMQEQEEMMWEQEEK--MQEQEEKMWEQ--EEKMREQEEKMRE-QEEKM 669

Query: 126 QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185
           Q    +   Q E  Q   EK  +R Q  ++  Q  ++  Q  ++  +   +  QE   RE
Sbjct: 670 QGQEEKMREQEEKMQGQEEK--MREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQE-EMRE 726

Query: 186 PCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRE 229
              R + +  +M    P  +  CS      S++L ++S T S E
Sbjct: 727 KEERIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVE 770



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 41/191 (21%), Positives = 98/191 (51%), Gaps = 11/191 (5%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
           E +++EQ  +    +E   E+  RL+E+ E++R     + E++   Q  +  R   +++ 
Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQE-KMWEQEEKMQEEERIREREKKMR 402

Query: 66  ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125
           E   ++RE+    ++Q E  WE++E+   ++Q+ ++  Q  +EK+   +    + +K  +
Sbjct: 403 EEEETMREQEEKMQKQEENMWEQEEK---EWQQQRLPEQ--KEKLWEQEKMQEQEEKIWE 457

Query: 126 QAYSARDSAQREI---SQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEAR 182
           Q    RD  Q E+    + +  ++ +R Q  ++ +Q  ++R Q +++  +   + +Q+ R
Sbjct: 458 QEEKIRD--QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515

Query: 183 TREPCPREKQR 193
            RE   R +++
Sbjct: 516 LREKEERMREQ 526



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 50/191 (26%), Positives = 99/191 (51%), Gaps = 21/191 (10%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
           ELQE+ LR A  ++S + +LN +KE   KL    F L +  +   +L E    ++E    
Sbjct: 191 ELQEK-LRLAESEKS-EIQLN-VKELKRKLERAKFLLPQ--VQTNTLQEEMWRQEE---- 241

Query: 68  IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE-RDQ 126
              LRE+     +Q E+ W ++E+  L+ Q+ KM  Q   EK+   + ++ E +KE R+Q
Sbjct: 242 --ELREQEKKIRKQEEKMWRQEER--LREQEGKMREQ--EEKMRRQEKRLREQEKELREQ 295

Query: 127 AYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREP 186
               R+  Q+++ +   +++ ++ Q  ++ +Q  ++R Q  ++  +   + +QE + RE 
Sbjct: 296 EKELRE--QKKLRE---QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 350

Query: 187 CPREKQRLVRM 197
             + + +  RM
Sbjct: 351 EQKMRDQEERM 361



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 33/183 (18%), Positives = 82/183 (44%), Gaps = 14/183 (7%)

Query: 14  LRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRE 73
           ++T + QE    +   L+E+ +K+R     +  +   E+ L E  G  +E  E++     
Sbjct: 227 VQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ---EERLREQEGKMREQEEKM----- 278

Query: 74  RAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDS 133
                 R++E+   E+E+ L + +K     +  RE+   +Q Q  ++ ++ ++     + 
Sbjct: 279 ------RRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332

Query: 134 AQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQR 193
             R+  +   ++  +R Q  ++ DQ   +  Q  +L+ +   + +QE    +    +++ 
Sbjct: 333 MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEE 392

Query: 194 LVR 196
            +R
Sbjct: 393 RIR 395



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 39/192 (20%), Positives = 86/192 (44%), Gaps = 34/192 (17%)

Query: 10  QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSR--QELVER 67
           QE+ +R   +Q+  D+E  R+ E++E+LR     + E+  + Q  ++ R  +  QE  ++
Sbjct: 491 QEEKMRD-QEQKMWDQE-ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK 548

Query: 68  IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127
                E+    ER RE+  + +E+            ++ RE+   +Q Q  +++++ ++ 
Sbjct: 549 TWDQEEKMREEERMREREKKMREEE-----------EMMREQEEKMQEQEEKMREQEEKM 597

Query: 128 YSARDSAQREISQSLVEK--------------DSLRRQVFELTDQVCELRTQLRQLQAEP 173
           +      Q E  Q   EK              D ++ Q   + +Q  +++ Q  ++  + 
Sbjct: 598 WE-----QEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE 652

Query: 174 PGVLKQEARTRE 185
             + +QE + RE
Sbjct: 653 EKMREQEEKMRE 664


>gi|46852390 coiled-coil domain containing 6 [Homo sapiens]
          Length = 474

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 67/252 (26%), Positives = 122/252 (48%), Gaps = 21/252 (8%)

Query: 9   LQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSR-QELVER 67
           LQ++    A + E  +E L      NE  R L     EK  LEQ L++ +  +  +L+++
Sbjct: 123 LQKEKETLAVNYEKEEEFLT-----NELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKK 177

Query: 68  IHSLRERAVAAERQREQYWEEK---EQTLLQFQKSKMACQLYREKVNALQAQVCELQKER 124
           I  L    ++ +   EQ   EK   E TL Q Q++ +  +L++ +++ L+A+   LQ++ 
Sbjct: 178 IKKLENDTISKQLTLEQLRREKIDLENTLEQEQEA-LVNRLWK-RMDKLEAEKRILQEKL 235

Query: 125 DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAE----PPGVLKQE 180
           DQ  SA  S  R+IS  +   +++ R +  L ++V  L+ QLR  Q +        L++E
Sbjct: 236 DQPVSAPPSP-RDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEE 294

Query: 181 ARTREPCPREKQRL----VRMHAICPRDDSDCSLVSSTESQLLSDLSATSSR-ELVDSFR 235
              RE   R +++L     R  A+C +     S +   + +  +++SA   R   V S  
Sbjct: 295 RHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPI 354

Query: 236 SSSPAPPSQQSL 247
             +P+P S + +
Sbjct: 355 PYTPSPSSSRPI 366


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 58/189 (30%), Positives = 90/189 (47%), Gaps = 23/189 (12%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
           E Q Q  +T   QE   + L    E+      L+ SL +K   EQ L E    +QE   +
Sbjct: 530 EKQAQLAQTLQQQEQASQGLRHQVEQ------LSSSLKQK---EQQLKEV-AEKQEATRQ 579

Query: 68  IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127
            H+ ++ A AAE +RE    E++  L Q +       L +EK   L+     LQ++   A
Sbjct: 580 DHA-QQLATAAE-EREASLRERDAALKQLEA------LEKEKAAKLEI----LQQQLQVA 627

Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPC 187
             ARDSAQ  ++Q+  EK  L R+V EL   V   R +  + QA+    L+ + R+ +  
Sbjct: 628 NEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQ-VAELELQLRSEQQK 686

Query: 188 PREKQRLVR 196
             EK+R+ +
Sbjct: 687 ATEKERVAQ 695



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 45/209 (21%), Positives = 84/209 (40%), Gaps = 19/209 (9%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
           ELEL+    R    ++  D ++  +++  ++L  L    A   +  + L+E R   + L 
Sbjct: 232 ELELELAENRKLLTEK--DAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLT 289

Query: 66  ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125
            R+H   ++    + ++ Q   +  Q   +        + +   +  LQ  + EL +E  
Sbjct: 290 MRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHS 349

Query: 126 QA----YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPP------- 174
           +A       +   ++E+S +L +K  L  +   L  ++ +L   L QLQ  PP       
Sbjct: 350 KATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVL 409

Query: 175 ------GVLKQEARTREPCPREKQRLVRM 197
                   LKQEA T      + Q  V M
Sbjct: 410 GDVLQLETLKQEAATLAANNTQLQARVEM 438



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 63/285 (22%), Positives = 120/285 (42%), Gaps = 39/285 (13%)

Query: 9    LQEQSLRTASDQESGDEELNRLK-------EENEKLRSLTFSLAEKDILEQ--------S 53
            LQE      +++E  D+EL +L+       +E E+LR     L E+   ++        +
Sbjct: 1048 LQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGA 1107

Query: 54   LDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREK-VNA 112
              EA G  +    ++ +LR      E+Q ++  +E+  +L +  +++ A +  R+  +  
Sbjct: 1108 QSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQ-QEQADSLERSLEAERASRAERDSALET 1166

Query: 113  LQAQVCELQKERDQAYSARDSAQREISQSLVE-------KDSLRRQVFELTDQVCELRTQ 165
            LQ Q+ E  +E   + SA  SAQRE++    +       +D  + QV     Q  E +  
Sbjct: 1167 LQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVAR-GRQEAERKNS 1225

Query: 166  LRQLQAEPPGVLKQEARTREPCPREKQRLV------------RMHAICPRDDSDCSLVSS 213
            L     E   +L ++   +E   +E +RLV            R+  +     S+ +  + 
Sbjct: 1226 LISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAE 1285

Query: 214  TESQLLSDLSATSSRELVDSFRSSSPAPPSQQSLYKRVAEDFGEE 258
              S L  ++   S RE  +  R +S     + +     AE+ G+E
Sbjct: 1286 RSSALREEVQ--SLREEAEKQRVASENLRQELTSQAERAEELGQE 1328



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 49/228 (21%), Positives = 88/228 (38%), Gaps = 13/228 (5%)

Query: 31   KEENEKLRSLTFSLAEKD----ILEQSLDEARGSRQELVERIHSLRERAVAAERQREQYW 86
            +E+ +++  L+  LA+ D    + +Q L   +    E  +    L+ +    + Q  Q  
Sbjct: 1545 REQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKE 1604

Query: 87   EEKEQTLLQFQKSKMACQLYREKVNALQAQVC---ELQKERDQAYSARDSAQREISQSLV 143
            +  E   LQ +K+K      +++   LQ Q+    +LQKE  +  +  +    E+ Q+ +
Sbjct: 1605 QAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGL 1664

Query: 144  EKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLVRMHAICPR 203
            +     +    LT QV  L  Q+     +   + K +  T     RE Q   ++      
Sbjct: 1665 KTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSI-- 1722

Query: 204  DDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSP----APPSQQSL 247
            D  D S    T   + S L  T           +SP     PP  +SL
Sbjct: 1723 DSLDLSCEEGTPLSITSKLPRTQPDGTSVPGEPASPISQRLPPKVESL 1770



 Score = 37.7 bits (86), Expect = 0.021
 Identities = 75/329 (22%), Positives = 127/329 (38%), Gaps = 41/329 (12%)

Query: 35   EKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLL 94
            E  R    +  E +++    + A+    E  +R    R++  A   Q E +  E+ + + 
Sbjct: 1493 EVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVE 1552

Query: 95   QFQK----SKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRR 150
            +  K    S  A ++ ++K+ A+QAQ  E Q+E  +  +  +  Q ++SQ     +  + 
Sbjct: 1553 ELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKL 1612

Query: 151  QVFEL-------TDQVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLVRMHAICPR 203
            Q+ +          Q  EL+ QLR L+     + K+    R    R    L +       
Sbjct: 1613 QMEKAKTHYDAKKQQNQELQEQLRSLEQ----LQKENKELRAEAERLGHELQQAGLKTKE 1668

Query: 204  DDSDC----SLVSSTESQL------LSDLSATSSRELVDSFRSSSPAPPSQQSLYKRVAE 253
             +  C    + V S E+Q+      L DL     +   D+ +S  P    Q  L     +
Sbjct: 1669 AEQTCRHLTAQVRSLEAQVAHADQQLRDLG--KFQVATDALKSREPQAKPQLDLSIDSLD 1726

Query: 254  DFGEE--PWSFSSCLEIPEGDPGALPGAKAG------DPHLD-YELLDTADLP-----QL 299
               EE  P S +S L   + D  ++PG  A        P ++  E L    +P      L
Sbjct: 1727 LSCEEGTPLSITSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPL 1786

Query: 300  ESSLQPVSPGRLDVSESGVLMRRRPARRI 328
            ESSL  +    LD        RRR  + I
Sbjct: 1787 ESSLDSLGDVFLDSGRKTRSARRRTTQII 1815



 Score = 37.4 bits (85), Expect = 0.027
 Identities = 50/239 (20%), Positives = 96/239 (40%), Gaps = 14/239 (5%)

Query: 4   SCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQE 63
           S ++E  +  + TA  ++   E   ++ E   +LRS      EK+ + Q  D+ +   Q 
Sbjct: 649 SRKVEELQACVETARQEQH--EAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQA 706

Query: 64  LVERI--------HSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQA 115
           L E +           R  A A E Q+    E K +T    ++ K   +   E+    + 
Sbjct: 707 LKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKG 766

Query: 116 QVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPP- 174
               LQ+  +   +  +  +RE+++++  + +   +  +L  +V   R +    Q E   
Sbjct: 767 LEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQ 826

Query: 175 -GVLKQE--ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSREL 230
            G + QE     +E C + +Q L          +S   L  S +   L++L A  +R L
Sbjct: 827 YGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARAL 885



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 50/223 (22%), Positives = 95/223 (42%), Gaps = 26/223 (11%)

Query: 25   EELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQ--ELVERIHSLRERAVAAERQR 82
            E+L  LKEE EK R       EK    +S  E + SRQ  EL E +H+   RA+      
Sbjct: 833  EQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAE-LHANLARAL------ 885

Query: 83   EQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSL 142
             Q  +EKE   ++ QK        +EK+ A   +V  L+    +A   +++A RE+ +  
Sbjct: 886  -QQVQEKE---VRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEP 941

Query: 143  VEKDSLRRQVFELTD--QVCELRTQLRQLQAEP-----------PGVLKQEARTREPCPR 189
                  + +  E     Q C  +  L+ ++ E              +++ + + +E   +
Sbjct: 942  ARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQ 1001

Query: 190  EKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVD 232
            +++ + R+     R  +D +L  +  ++L   L    + + V+
Sbjct: 1002 QEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVE 1044



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 44/200 (22%), Positives = 77/200 (38%), Gaps = 21/200 (10%)

Query: 6    ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
            + E    S R A    +  EE+  L+EE EK R  + +L                RQEL 
Sbjct: 1273 QAETASNSARAAERSSALREEVQSLREEAEKQRVASENL----------------RQELT 1316

Query: 66   ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125
             +     E     +  +E+++ +KEQ L   Q    + Q    ++   +    +LQ E+ 
Sbjct: 1317 SQAERAEELGQELKAWQEKFF-QKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQ- 1374

Query: 126  QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185
               +A    + E+ QS      LR ++     ++ EL   LRQ  AE     +Q    + 
Sbjct: 1375 --AAAEKRHREELEQSKQAAGGLRAELLRAQRELGEL-IPLRQKVAEQERTAQQLRAEKA 1431

Query: 186  PCPREKQRLVRMHAICPRDD 205
                +   L + H +   ++
Sbjct: 1432 SYAEQLSMLKKAHGLLAEEN 1451



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 44/191 (23%), Positives = 80/191 (41%), Gaps = 33/191 (17%)

Query: 6    ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEK-----DILEQSLDEARGS 60
            E E   Q LR  +++ S  E+L+ LK+ +  L      L E+       LE  LD+AR  
Sbjct: 1418 EQERTAQQLR--AEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREK 1475

Query: 61   --------RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNA 112
                    R +   R+  ++  A +  R+ E    + E   ++  + +   Q  R+K+ A
Sbjct: 1476 YVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTA 1535

Query: 113  LQAQVCELQKERDQAYSARDSAQREISQSLVEKD-----------SLRRQVFELTDQVCE 161
               Q+   Q+E+ +          E+S+ L + D           +++ Q  E   +   
Sbjct: 1536 QVEQLEVFQREQTKQV-------EELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQR 1588

Query: 162  LRTQLRQLQAE 172
            L+ QL +LQA+
Sbjct: 1589 LQAQLNELQAQ 1599



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 52/226 (23%), Positives = 96/226 (42%), Gaps = 29/226 (12%)

Query: 2   VSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAE-KDILEQSLDEARGS 60
           V   E E  +Q  +  +++   +EE  +L      L+S   +L++ K+ LEQ+  +A G+
Sbjct: 436 VEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQA-SQAHGA 494

Query: 61  RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL 120
           R  L  ++ SL           +Q  +++   L Q  K K             QAQ+ + 
Sbjct: 495 R--LTAQVASLTSELTTLNATIQQQ-DQELAGLKQQAKEK-------------QAQLAQT 538

Query: 121 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFE-----LTDQVCELRTQLRQLQA---E 172
            ++++QA         ++S SL +K+   ++V E       D   +L T   + +A   E
Sbjct: 539 LQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRE 598

Query: 173 PPGVLKQ-EARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQ 217
               LKQ EA  +E     K  +++       +  D +  S T++Q
Sbjct: 599 RDAALKQLEALEKEKA--AKLEILQQQLQVANEARDSAQTSVTQAQ 642


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 35/161 (21%), Positives = 78/161 (48%), Gaps = 9/161 (5%)

Query: 10  QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIH 69
           QE+ +R   ++    EE  +++E+ EK+R     + E++ + Q  +E  G ++E ++   
Sbjct: 507 QEEKIREQEEKMWRQEE--KIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE 564

Query: 70  SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYS 129
            +R +      Q E+  E+KE+   Q +K     +  RE+   +Q Q  ++ ++ ++   
Sbjct: 565 KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE 624

Query: 130 ARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ 170
             +  Q        +++ +RRQ  ++ +Q   LR Q  ++Q
Sbjct: 625 QEEKMQE-------QEEKMRRQEEKMWEQEVRLRQQEEKMQ 658



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 42/188 (22%), Positives = 88/188 (46%), Gaps = 18/188 (9%)

Query: 10  QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIH 69
           Q+Q  +    +E   E   +++E+ EK+R       E+ I EQ   E +  RQE      
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIRE-----QEEKIREQ---EEKMRRQE-----E 342

Query: 70  SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYS 129
            + E+     RQ E  WE++E    + ++ +       EK+  L+ ++ E +K R+Q   
Sbjct: 343 MMWEKEEKMRRQEEMMWEKEE----KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK 398

Query: 130 ARDSAQ-REISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCP 188
            ++  + RE  +   ++  + RQ  ++ +Q  ++R Q +++  +   + +QE    E   
Sbjct: 399 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 458

Query: 189 REKQRLVR 196
           +E++ + R
Sbjct: 459 QEQEEMWR 466



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 51/194 (26%), Positives = 91/194 (46%), Gaps = 26/194 (13%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
           E E + Q      +QE   E+  ++  + EK+R       E+ I EQ   E +  RQE  
Sbjct: 394 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE-----QEEKIREQ---EKKMWRQE-- 443

Query: 66  ERIHSLRERAVAAERQ-REQYWEE----KEQTLLQFQKSKMACQLYREKVNALQAQVC-E 119
           E+IH   +     +RQ +E+ W +    +EQ  +  QK KM  Q   EK+   + +V  +
Sbjct: 444 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ---EKIRKQEEKVWRQ 500

Query: 120 LQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQ 179
            +K  DQ    R+  ++   Q    ++ +R Q  ++ +Q  ++R Q   +Q +   + +Q
Sbjct: 501 EEKMHDQEEKIREQEEKMWRQ----EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ 556

Query: 180 EARTREPCPREKQR 193
           E + +E   +EK R
Sbjct: 557 EEKMQE---QEKMR 567



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 26/131 (19%), Positives = 63/131 (48%), Gaps = 6/131 (4%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
           E+ ++      +QE   +E  +++ + EK+R       E+ I EQ  ++ R   +++ E+
Sbjct: 544 EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIRE-----QEEKIREQK-EKIREQEEKIWEQ 597

Query: 68  IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127
              +RE+    + Q E+ WE++E+   Q +K +   +  R +   +  Q   L+++ ++ 
Sbjct: 598 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 657

Query: 128 YSARDSAQREI 138
              ++  +  I
Sbjct: 658 QEHQEHLEAAI 668



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 41/199 (20%), Positives = 93/199 (46%), Gaps = 23/199 (11%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSL---AEKDILEQSLD------EAR 58
           +LQE+     S++      +  LK + E+ + L       AE D L + L       +A+
Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284

Query: 59  GSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVC 118
               EL  R++  +E  +  + ++ Q WEEK    +Q Q+ K+     RE+   ++ Q  
Sbjct: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEK----IQEQEEKI-----REQEEKIREQEE 335

Query: 119 ELQKERDQAYSARDSAQREISQSLVEKDSLRR---QVFELTDQVCELRTQLRQLQ--AEP 173
           +++++ +  +   +  +R+      +++ +RR    ++E  +++ EL  ++ + +   E 
Sbjct: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ 395

Query: 174 PGVLKQEARTREPCPREKQ 192
               ++E + RE   R++Q
Sbjct: 396 EEKRQEEEKIREQEKRQEQ 414



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 25/176 (14%), Positives = 90/176 (51%), Gaps = 9/176 (5%)

Query: 10  QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIH 69
           +++ +R   ++    EE  ++ ++ EK+R       +++ + +  ++ R   +++ E+  
Sbjct: 486 EQEKIRKQEEKVWRQEE--KMHDQEEKIRE------QEEKMWRQEEKIREQEEKIREQEE 537

Query: 70  SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYS 129
            +RE+    + Q E+  E++E+ + + +K +   +  RE+   ++ Q  +++++ ++ + 
Sbjct: 538 KIREQEEMMQEQEEKMGEQEEK-MQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWE 596

Query: 130 ARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185
             +  + +      +++ +  Q  ++ +Q  +++ Q  +++ +   + +QE R R+
Sbjct: 597 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 652



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 35/200 (17%), Positives = 92/200 (46%), Gaps = 10/200 (5%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
           E ++QE   +    +E   E+  +++E+ EK+R     + EK+   +  +E    ++E +
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365

Query: 66  ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125
            R+  +        R+ E+   E+E+   Q +K        R++   ++ Q  E ++E++
Sbjct: 366 RRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK--------RQEEEKIREQ--EKRQEQE 415

Query: 126 QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185
                ++   RE  + + E++    +  E   +  ++R + ++ + E     +++ R +E
Sbjct: 416 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 475

Query: 186 PCPREKQRLVRMHAICPRDD 205
              R+K+++     I  +++
Sbjct: 476 EIWRQKEKMHEQEKIRKQEE 495



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 23/107 (21%), Positives = 57/107 (53%), Gaps = 10/107 (9%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
           E +++EQ  +    +E   E+  ++ E+ EK+R       +++++++  ++     +++ 
Sbjct: 570 EEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE------QEEMMQEQEEKMWEQEEKMC 623

Query: 66  ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNA 112
           E+   ++E+     RQ E+ WE  ++  L+ Q+ KM  Q ++E + A
Sbjct: 624 EQEEKMQEQEEKMRRQEEKMWE--QEVRLRQQEEKM--QEHQEHLEA 666



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 41/184 (22%), Positives = 86/184 (46%), Gaps = 26/184 (14%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKE---ENEKLRSLTFSL-AEKDILEQSLDEARGSR 61
           E+  QE+ +R         EE+ R KE   E EK+R     +  +++ +    ++ R   
Sbjct: 463 EMWRQEEKIRE-------QEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQE 515

Query: 62  QELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQ 121
           +++  +   +RE+     R++E+   E+E+ ++Q Q+ KM  Q   EK+   +    + +
Sbjct: 516 EKMWRQEEKIREQEEKI-REQEEKIREQEE-MMQEQEEKMGEQ--EEKMQEQEKMRRQEE 571

Query: 122 KERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEA 181
           K R+Q    R+           +K+ +R Q  ++ +Q  ++R Q   +Q +   + +QE 
Sbjct: 572 KIREQEEKIRE-----------QKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620

Query: 182 RTRE 185
           +  E
Sbjct: 621 KMCE 624


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 58/236 (24%), Positives = 105/236 (44%), Gaps = 17/236 (7%)

Query: 8    ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
            E++ +  R  + QE G+ ++ + K   E L  LT +LAE+   E+ ++  RG  QEL ++
Sbjct: 1394 EVESERERAQALQEQGELKVAQGKALQENLALLTQTLAER---EEEVETLRGQIQELEKQ 1450

Query: 68   IH-----------SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQ 116
                          L++R    + Q+EQ  +E E+     +   MA Q   +K+   + Q
Sbjct: 1451 REMQKAALELLSLDLKKRNQEVDLQQEQI-QELEKCRSVLEHLPMAVQEREQKLTVQREQ 1509

Query: 117  VCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGV 176
            + EL+K+R+   +  +    E+ +     +S R QV +L  Q+  L     +L+     +
Sbjct: 1510 IRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKM 1569

Query: 177  LKQEARTRE-PCPREKQRLVRMHAICPRDDSDCSL-VSSTESQLLSDLSATSSREL 230
              Q+   +E    RE QR+   H     ++    L   S++   L   S   +REL
Sbjct: 1570 ECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLAREL 1625



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 49/200 (24%), Positives = 93/200 (46%), Gaps = 21/200 (10%)

Query: 6    ELELQEQSLRTASDQESG--DEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQE 63
            +L   EQ  +TA +Q+    ++E+N+L+E+ EK RS       +  L ++L+     + E
Sbjct: 832  QLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSW-----HQQELAKALESLEREKME 886

Query: 64   LVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE 123
            L  R+   +    A + QRE+   + E  L Q Q      +  +E+V+ L+  + + QKE
Sbjct: 887  LEMRLKEQQTEMEAIQAQREEERTQAESALCQMQ-----LETEKERVSLLET-LLQTQKE 940

Query: 124  RDQAYSARDSAQREIS-QSLVEKDS-------LRRQVFELTDQVCELRTQLRQLQAEPPG 175
               A    +  ++++  Q L E+++       L+    EL +   + R  L  LQ E   
Sbjct: 941  LADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSS 1000

Query: 176  VLKQEARTREPCPREKQRLV 195
            +L+ +   ++     K +LV
Sbjct: 1001 LLQDKMDLQKQVEDLKSQLV 1020



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 61/233 (26%), Positives = 105/233 (45%), Gaps = 45/233 (19%)

Query: 11  EQSLRTASDQESG-DEELNRLKEENEKLRSLTFSLA-EKDILEQSLDEARGSRQELVERI 68
           EQS+   S  E+    E+  L+    KL +L  +LA +K  L Q L +     Q +  R+
Sbjct: 574 EQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRM 633

Query: 69  HSLRERAVA-------AERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQ 121
            +  +   A       AE++RE  WE+      Q QK++       E    LQA + ++Q
Sbjct: 634 EAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAE-------EAGAELQADLRDIQ 686

Query: 122 KERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEA 181
           +E+++        Q+++S+S  ++++   Q+            QL Q       VL +  
Sbjct: 687 EEKEE-------IQKKLSESRHQQEAATTQL-----------EQLHQEAKRQEEVLARAV 728

Query: 182 RTREPCPREKQRL-VRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDS 233
           + +E   REK  L VR+ A+  RD  D        ++ L  LS  S++EL++S
Sbjct: 729 QEKEALVREKAALEVRLQAV-ERDRQDL-------AEQLQGLS--SAKELLES 771



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 55/228 (24%), Positives = 97/228 (42%), Gaps = 15/228 (6%)

Query: 2    VSSCELELQEQSLRTASDQESGDEELNRLKEEN--EKLRSLTFSLAEK-------DILEQ 52
            ++S +  L+   L+    Q  G+ EL +  +EN   ++  L  ++ E         ILE+
Sbjct: 1322 MASLQSRLRRAELQRMEAQ--GERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEE 1379

Query: 53   SLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNA 112
             L  AR + +   E + S RERA A + Q E    + +                 E+V  
Sbjct: 1380 DLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVET 1439

Query: 113  LQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTD--QVCELRTQLRQLQ 170
            L+ Q+ EL+K+R+   +A +    ++ +   E D  + Q+ EL     V E      Q +
Sbjct: 1440 LRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQER 1499

Query: 171  AEPPGVLKQEARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQL 218
             +   V +++ R  E   RE QR V  H +   +  D  ++ S   Q+
Sbjct: 1500 EQKLTVQREQIRELEK-DRETQRNVLEHQLLELEKKD-QMIESQRGQV 1545



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 46/184 (25%), Positives = 77/184 (41%), Gaps = 33/184 (17%)

Query: 6    ELELQEQSLRTASDQESGDEELNRLKEENEKLR-SLTFSLAEKD---------------- 48
            E E+QE+   T        +E NR+++E E+ + SLT SL EK+                
Sbjct: 1030 EQEVQEKLRET--------QEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQE 1081

Query: 49   --ILEQSLDEARGSRQELVERIHSLRERAVAAE----RQREQYWEEKEQTLLQFQKSKMA 102
               L Q + EA+G ++EL  ++  LR+     E     Q  Q  EE E +     + ++ 
Sbjct: 1082 LSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEAS--HITEQQLR 1139

Query: 103  CQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCEL 162
              L+ ++  A Q Q+     E      A +      +Q+  +  SL   + +    VCE 
Sbjct: 1140 ASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCES 1199

Query: 163  RTQL 166
            R +L
Sbjct: 1200 RPEL 1203



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 45/193 (23%), Positives = 79/193 (40%), Gaps = 12/193 (6%)

Query: 8    ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
            ELQ Q      D E  D+EL   KE  + L        +  ILE+ L++ + S +E    
Sbjct: 1641 ELQRQKEHLTQDLERRDQELMLQKERIQVLEDQR--TRQTKILEEDLEQIKLSLRERGRE 1698

Query: 68   IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127
            + +  +R +  ER  E     K Q     +  K+  +   ++V   Q  + ELQ+ +DQ 
Sbjct: 1699 LTT--QRQLMQERAEEGKGPSKAQRG-SLEHMKLILRDKEKEVECQQEHIHELQELKDQL 1755

Query: 128  YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQ-------LRQLQAEPPGVLKQE 180
                    R++ ++ +      +++  L  Q+ E R Q       L+    E    L Q 
Sbjct: 1756 EQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQR 1815

Query: 181  ARTREPCPREKQR 193
             +  E   +E+Q+
Sbjct: 1816 DQELEALQQEQQQ 1828



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 43/169 (25%), Positives = 75/169 (44%), Gaps = 6/169 (3%)

Query: 20  QESGDEELNRLKEENEKLRSLTFSLAEK--DILEQSLDEARGSRQELVERIHSLRERAVA 77
           Q SG E  N L+ ++       +  A+K   ++   L   R + Q+L +++   +E    
Sbjct: 361 QGSGHE--NSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNL 418

Query: 78  AERQREQYWEEKEQTLLQ-FQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQR 136
            ++Q +Q WEE+ + L Q  QK          +   LQ +V  L KER+    AR+  ++
Sbjct: 419 LQQQHDQ-WEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQ 477

Query: 137 EISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185
           ++     E   LRR   EL  Q    + Q  + Q E    +++  R +E
Sbjct: 478 QLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQE 526



 Score = 38.1 bits (87), Expect = 0.016
 Identities = 41/171 (23%), Positives = 81/171 (47%), Gaps = 17/171 (9%)

Query: 6    ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKD----ILEQSLDEARGSR 61
            E+E Q++ +     QE  D+   +L+  + K+   +  L++++    +L+Q L EAR   
Sbjct: 1737 EVECQQEHIHEL--QELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQG 1794

Query: 62   QELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQV---- 117
            +   + + S  + A  A  QR+Q  E  +Q   Q Q  +   +  +EK +ALQ  +    
Sbjct: 1795 ELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQE---ERVKEKADALQGALEQAH 1851

Query: 118  CELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQ 168
              L++   +    ++ A+R   +  VE     R+V  L + + +LR + R+
Sbjct: 1852 MTLKERHGELQDHKEQARRLEEELAVE----GRRVQALEEVLGDLRAESRE 1898



 Score = 38.1 bits (87), Expect = 0.016
 Identities = 53/252 (21%), Positives = 103/252 (40%), Gaps = 19/252 (7%)

Query: 3    SSCELELQEQSLRTASDQESGDEELNRLKEEN------EKLRSLTFSLAEKDILEQSLDE 56
            +S  L  +EQ +     Q     E   LKE++      E  R+L     E + L+Q   +
Sbjct: 1769 TSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQ 1828

Query: 57   ARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQ 116
            A+G  + + E+  +L+     A    ++   E +    Q ++ +    +   +V AL+  
Sbjct: 1829 AQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEV 1888

Query: 117  VCELQKERDQAYSARDSAQREISQSL----VEKDSLRRQVFELTDQVCELRTQLRQLQAE 172
            + +L+ E  +   A  + Q++ ++      VE  +L+    +    + E   +L  L+AE
Sbjct: 1889 LGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAE 1948

Query: 173  PPGVLKQEARTREPCPREKQRLVRMHA--------ICPRDDSDCSLVSSTES-QLLSDLS 223
                  QE   R      ++ L + HA        +  + +   SL +ST + Q   D  
Sbjct: 1949 SQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDAC 2008

Query: 224  ATSSRELVDSFR 235
               SR+L ++ R
Sbjct: 2009 QAHSRQLEEALR 2020



 Score = 37.4 bits (85), Expect = 0.027
 Identities = 19/82 (23%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 98   KSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEK-------DSLRR 150
            K++    + R++V  L+ ++ + + E+ Q ++     QR++SQ+  EK       +SL  
Sbjct: 1254 KTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLES 1313

Query: 151  QVFELTDQVCELRTQLRQLQAE 172
            ++ EL + +  L+++LR+ + +
Sbjct: 1314 ELMELHETMASLQSRLRRAELQ 1335



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 34/168 (20%), Positives = 73/168 (43%), Gaps = 1/168 (0%)

Query: 24  DEELNRLKEENEKLRS-LTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAAERQR 82
           + +L + +E   +L++ L     EK+ +++ L E+R  ++    ++  L + A   E   
Sbjct: 665 EAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVL 724

Query: 83  EQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSL 142
            +  +EKE  + +    ++  Q        L  Q+  L   ++   S+   AQ++ S   
Sbjct: 725 ARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIE 784

Query: 143 VEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPRE 190
           V K  L  Q+  +T     ++ ++R L+ E      Q  + R+   R+
Sbjct: 785 VTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQ 832



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 35/165 (21%), Positives = 74/165 (44%), Gaps = 14/165 (8%)

Query: 7   LELQEQSLRTASDQESGDEE-LNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
           L  + Q+++    Q +G +E +N L++++++         E   L Q L +  G R  L 
Sbjct: 395 LTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEE------EGKALRQRLQKLTGERDTLA 448

Query: 66  ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125
            +   L+    +  ++RE   + +E+   Q +  +      R +VN       ELQ + D
Sbjct: 449 GQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLR-RVNV------ELQLQGD 501

Query: 126 QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ 170
            A   ++  Q E+  ++ E++ L+  +  L  +  E  ++L  L+
Sbjct: 502 SAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLR 546



 Score = 29.6 bits (65), Expect = 5.6
 Identities = 49/218 (22%), Positives = 92/218 (42%), Gaps = 31/218 (14%)

Query: 8   ELQEQ-----SLRTASDQESGDEE--LNRLKEENEKLRSLTFSLAEKDI-LEQSLDEARG 59
           ELQ++     +L T S +++ D E  +  L+E  E L +    L E +  L ++  E + 
Sbjct: 280 ELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKL 339

Query: 60  SRQELVERIHSLRERA---VAAERQREQYWEEKEQTLLQFQ----------------KSK 100
           S Q++++ I  +       +A     E   E       QF                 + +
Sbjct: 340 SLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRR 399

Query: 101 MACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVC 160
            A Q  R+++   Q  V  LQ++ DQ      + ++ + +   E+D+L  Q  +L  +V 
Sbjct: 400 QAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVD 459

Query: 161 ELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLVRMH 198
            L  + R+L  +    L+Q+    E   +E  RL R++
Sbjct: 460 SLSKE-RELLQKAREELRQQLEVLE---QEAWRLRRVN 493



 Score = 29.6 bits (65), Expect = 5.6
 Identities = 44/169 (26%), Positives = 72/169 (42%), Gaps = 37/169 (21%)

Query: 6    ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
            ELE Q ++ R A    + D     L+E +++L++ +  + +   LE          QE  
Sbjct: 1578 ELEGQRETQRVALTHLTLD-----LEERSQELQAQSSQIHD---LESHSTVLARELQERD 1629

Query: 66   ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125
            + + S RE+    +RQ+E   ++ E+                      + Q   LQKER 
Sbjct: 1630 QEVKSQREQIEELQRQKEHLTQDLER----------------------RDQELMLQKERI 1667

Query: 126  QAYSARDSAQREISQSLVE--KDSLRRQVFELTDQVCELRTQLRQLQAE 172
            Q    + + Q +I +  +E  K SLR +  ELT Q      QL Q +AE
Sbjct: 1668 QVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQ-----RQLMQERAE 1711


>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
           sapiens]
          Length = 631

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 65/279 (23%), Positives = 125/279 (44%), Gaps = 16/279 (5%)

Query: 8   ELQEQSLRTASD----QESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQE 63
           +LQE+  R   +    QE+  +    L+EE E+ RS    L +   LE  L EA  +R  
Sbjct: 352 QLQEEKERKLQELELLQEAQRQAERLLQEEEERRRSQHRELQQA--LEGQLREAEQARAS 409

Query: 64  LVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE 123
           +   +  L+E   A +RQR +  EE +Q L +  + ++  +   E V   Q ++ E ++E
Sbjct: 410 MQAEME-LKEEEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEE 468

Query: 124 R-DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQL----QAEPPGVLK 178
           +  Q    ++  +R I ++  EK+ L++++ + +  + + + QL ++    Q     V  
Sbjct: 469 KLKQLMQLKEEQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEA 528

Query: 179 QEARTREPCPREKQRLVR----MHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSF 234
            + + R+     K   V+    MH I P D    +  S +  Q        SS + +  +
Sbjct: 529 AQRKLRQASTNVKHWNVQMNRLMHPIEPGDKRPVTSSSFSGFQPPLLAHRDSSLKRLTRW 588

Query: 235 RSSSPAPPSQQSLYKRVAEDFGEEPWSFSSCLEIPEGDP 273
            S     PS  S  ++ + + G+E  + +S  +  + DP
Sbjct: 589 GSQGNRTPSPNSNEQQKSLNGGDEAPAPASTPQEDKLDP 627



 Score = 32.3 bits (72), Expect = 0.86
 Identities = 35/133 (26%), Positives = 55/133 (41%), Gaps = 20/133 (15%)

Query: 71  LRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSA 130
           L+++      QRE+    KE+ LL+ Q      QL  EK   LQ    EL +E       
Sbjct: 325 LKQKRREQREQRERRRAAKEEELLRLQ------QLQEEKERKLQE--LELLQE------- 369

Query: 131 RDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPRE 190
              AQR+  + L E++  RR       Q   L  QLR+ +     +  +     E   R+
Sbjct: 370 ---AQRQAERLLQEEEERRRSQHRELQQA--LEGQLREAEQARASMQAEMELKEEEAARQ 424

Query: 191 KQRLVRMHAICPR 203
           +QR+  +  +  R
Sbjct: 425 RQRIKELEEMQQR 437


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 52/209 (24%), Positives = 98/209 (46%), Gaps = 28/209 (13%)

Query: 1    MVSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGS 60
            +++  E E +E S   A+ Q+  DE L  L  E+EK ++L+   +EK  L + L   R  
Sbjct: 1027 LLARLEAEKEELSEEIAALQQERDEGL--LLAESEKQQALSLKESEKTALSEKLMGTR-- 1082

Query: 61   RQELVERIHSLRERAVAAERQRE--QYWEEKEQTLLQFQKSKM---------ACQLYREK 109
                    HSL   ++  ERQ+   Q  +E++++ +    S++         A   + ++
Sbjct: 1083 --------HSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQE 1134

Query: 110  VNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQL 169
            V  LQ Q  +L K+RD      +  + ++      +D LRR++ E   ++ E + + R++
Sbjct: 1135 VRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQ-EGREV 1193

Query: 170  QAEPPGVLKQE----ARTREPCPREKQRL 194
            Q +  G L++     A+ RE   R  + L
Sbjct: 1194 QRQEAGELRRSLGEGAKEREALRRSNEEL 1222



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 40/185 (21%), Positives = 82/185 (44%), Gaps = 22/185 (11%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSL-------------TFSLAE--KDILEQ 52
           +L+E+       Q   ++E    +EE E+L  L             +  +AE  ++ LEQ
Sbjct: 761 QLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQ 820

Query: 53  SLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNA 112
            L   R  R +L E++  L  +    E++ EQ   E ++ +   +++    +   ++   
Sbjct: 821 QLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAG 880

Query: 113 LQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAE 172
           L  Q+   ++E         +   E ++  +EK++L   +FE+  Q+ +L  +  QL+AE
Sbjct: 881 LAVQLVAAERE-------GRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAE 933

Query: 173 PPGVL 177
              +L
Sbjct: 934 GQALL 938



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 64/269 (23%), Positives = 116/269 (43%), Gaps = 54/269 (20%)

Query: 6    ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
            +LE + Q+L  A +  +G  EL  L+++   + +   +  +K+++ Q L +A    Q   
Sbjct: 929  QLEAEGQALLLAKETLTG--ELAGLRQQI--IATQEKASLDKELMAQKLVQAEREAQA-- 982

Query: 66   ERIHSLRERAVAAE-------RQREQYWEEKE------QTLLQFQKSKMACQLYREKVNA 112
                SLRE+  A E       R++E  W E E      Q+ LQ ++ ++  +L  EK   
Sbjct: 983  ----SLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEK-EE 1037

Query: 113  LQAQVCELQKERD-----------QAYSARDSAQREISQSL-----------VEKDSLRR 150
            L  ++  LQ+ERD           QA S ++S +  +S+ L           +E +  +R
Sbjct: 1038 LSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKR 1097

Query: 151  QVFELTDQ----VCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLVRMHAICPRDDS 206
                  +Q    V  L ++LR L+A+        A+       + + L +    C R+  
Sbjct: 1098 DAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAE 1157

Query: 207  DCSLVSSTESQLLSDLSATSSRELVDSFR 235
            +      T+ +LL D      REL+++ R
Sbjct: 1158 EL----RTQLRLLEDARDGLRRELLEAQR 1182



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 51/203 (25%), Positives = 86/203 (42%), Gaps = 18/203 (8%)

Query: 7   LELQEQSLRTASD-----QESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSR 61
           LE Q Q LR  +D      E    E+ RL+  NE L        EK  L  SL  A+   
Sbjct: 566 LEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSR------EKSNLAHSLQVAQQQA 619

Query: 62  QELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQ 121
           +EL +    L+       RQR++  EE+E  +    + +   +    ++  L+ +   L 
Sbjct: 620 EELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLA 679

Query: 122 KERDQAYSA--RDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGV--- 176
           KE  +   A  R + QR++ Q+  EK  +   + +      EL   + +L+AE   +   
Sbjct: 680 KELVEVREALSRATLQRDMLQA--EKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDS 737

Query: 177 LKQEARTREPCPREKQRLVRMHA 199
           L + +   E   ++K  L R+ A
Sbjct: 738 LSKLSALNESLAQDKLDLNRLVA 760



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 59/246 (23%), Positives = 110/246 (44%), Gaps = 29/246 (11%)

Query: 11   EQSLRTASD-QESGDEELNRLKEENEKLRSLTFSLAEK-DILEQSLDEARGSRQELVERI 68
            E SLR A   QE+ +++L  L+ E  +L+     L+ +    EQ L++AR   Q  VE +
Sbjct: 805  EGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEAL 864

Query: 69   H--------------SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLY--REKVNA 112
                            L  + VAAER+     E  E T L+ +K  +   L+  + ++  
Sbjct: 865  ERAAREKEALAKEHAGLAVQLVAAEREGRTLSE--EATRLRLEKEALEGSLFEVQRQLAQ 922

Query: 113  LQAQVCELQKERDQAYSARDSAQREIS---QSLV---EKDSLRRQVF--ELTDQVCELRT 164
            L+A+  +L+ E      A+++   E++   Q ++   EK SL +++   +L     E + 
Sbjct: 923  LEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQA 982

Query: 165  QLRQLQAEPPGVLKQEARTREPCPRE-KQRLVRMHAICPRDDSDCSLVSSTESQLLSDLS 223
             LR+ +A     L++  R +E   RE +    ++ +   R+  +       E + LS+  
Sbjct: 983  SLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEI 1042

Query: 224  ATSSRE 229
            A   +E
Sbjct: 1043 AALQQE 1048



 Score = 37.7 bits (86), Expect = 0.021
 Identities = 68/328 (20%), Positives = 139/328 (42%), Gaps = 34/328 (10%)

Query: 50  LEQSLDEARGSRQELVERIHSLRERAVAA-----ERQREQYWEEKEQTLLQFQKSKMACQ 104
           L + L ++   R+ L E++  LR++   A     + QRE         LL  +KS +A  
Sbjct: 552 LRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHS 611

Query: 105 LY---------REKVNALQAQVCELQKERDQAYSARDSA-------QREISQSLVEKDSL 148
           L          R++   LQA   EL+++RD+    ++ A       +RE+ +S  + + L
Sbjct: 612 LQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQL 671

Query: 149 RRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLVRMHAICPRDDSDC 208
             +   L  ++ E+R  L +   +   +  ++A   E   + +   V +     +  ++ 
Sbjct: 672 EGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEE 731

Query: 209 SLVSSTESQLLSDLSATSSRELVDSFRSSSPAPPSQQSLYKR---------VAEDFGEEP 259
           + +  + S+ LS L+ + +++ +D  R  +     + +L  R         VA +  E  
Sbjct: 732 ASLQDSLSK-LSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERL 790

Query: 260 WSFSSCLEIP-EGDPGALPGAKAGDPHLDYELLDTA-DLPQLESSLQPVSPGRLDVSESG 317
                  E+  +G  G+L  A+     L+ +L     +  QL+  L  +S  +L   E  
Sbjct: 791 EELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLS-RQLSGREQE 849

Query: 318 VLMRRRPARRILSQVTMLAFQGDALLEQ 345
           +   RR A+R +  +   A + +AL ++
Sbjct: 850 LEQARREAQRQVEALERAAREKEALAKE 877



 Score = 37.0 bits (84), Expect = 0.035
 Identities = 64/267 (23%), Positives = 118/267 (44%), Gaps = 35/267 (13%)

Query: 2    VSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSR 61
            +++CE + Q    R  + +++  E   +     E++++L   +A+   LE    EA G  
Sbjct: 1756 LTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVAD---LELQRVEAEGQL 1812

Query: 62   QELVERIHSLRERAVAAERQREQYWEEK---EQTLLQFQKSKMACQLYREKVNALQAQVC 118
            Q+L E +   +E   AA    ++  +E+   ++ L   Q++    QL  EK   ++    
Sbjct: 1813 QQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRA--LAQLEAEK-REVERSAL 1869

Query: 119  ELQKERDQAYSARDSAQREISQS-------LVEKDSLRRQVFELTDQVCELRTQLRQLQA 171
             L+K+R       D  +RE  +S         EK  L R +     ++ E + Q++QL+A
Sbjct: 1870 RLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEA 1929

Query: 172  E--------PPGVLKQEARTRE-PCPREKQRLVRMHA-----ICPRDDSDCSLVSSTESQ 217
            +         P  L+ +A+ ++    +E +RL    A     +  R+ +    V   E Q
Sbjct: 1930 QVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVRGLEEQ 1989

Query: 218  LLSDLSATSSRELVDSFRSSSP-APPS 243
             +S L     +EL    RSS+P +PPS
Sbjct: 1990 -VSTLKGQLQQEL---RRSSAPFSPPS 2012



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 6/88 (6%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
           EL++Q LR     +  +  L RL+EE ++  SL    A   +L + LD+A  + Q L E 
Sbjct: 200 ELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNA---MLREQLDQAGSANQALSED 256

Query: 68  IHSLRERAVAAERQ---REQYWEEKEQT 92
           I  +        ++   RE  W  +E++
Sbjct: 257 IRKVTNDWTRCRKELEHREAAWRREEES 284



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 49/203 (24%), Positives = 79/203 (38%), Gaps = 24/203 (11%)

Query: 4    SCELELQEQSLRTASDQESGDEELNRLKEENEKLRSLT----FSLAEKDILEQSLDEARG 59
            SC  E +E   +    +++ D     L E   KLR           E   L +SL E   
Sbjct: 1151 SCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAK 1210

Query: 60   SRQELVERIHSLRERAVAAERQREQYW---EEKEQTLLQFQKSKMACQLYREKVNALQAQ 116
             R+ L      LR     AE +R       E+KEQ L   ++++           A+  +
Sbjct: 1211 EREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEAR----------TAVGKE 1260

Query: 117  VCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGV 176
              EL+    +   +R  A+RE+ +       LRRQ+  L  +   L  +L +LQ      
Sbjct: 1261 AGELRTGLQEVERSRLEARRELQE-------LRRQMKMLDSENTRLGRELAELQGRLALG 1313

Query: 177  LKQEARTREPCPREKQRLVRMHA 199
             + E  +R      +QRL++  A
Sbjct: 1314 ERAEKESRRETLGLRQRLLKGEA 1336



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 44/178 (24%), Positives = 81/178 (45%), Gaps = 24/178 (13%)

Query: 17   ASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEA--------------RGSRQ 62
            AS+  +   EL R   E E  RS    L++++   Q+L +                G+ Q
Sbjct: 1646 ASESRTVKLELQRRSLEGELQRS-RLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQ 1704

Query: 63   ELVERIHSLRERAVAAERQREQYWEEKEQTLLQ-FQKSKMACQLYREKVNALQAQVCELQ 121
              VER++     A+A   + E    +K + L +   +S  +    R+K   LQ  +   +
Sbjct: 1705 LTVERLNG----ALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACE 1760

Query: 122  KERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQ 179
             +R       D+A++ +S++  +  SL  QV  L  +V +L  +L++++AE  G L+Q
Sbjct: 1761 HDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADL--ELQRVEAE--GQLQQ 1814



 Score = 33.1 bits (74), Expect = 0.51
 Identities = 47/250 (18%), Positives = 98/250 (39%), Gaps = 31/250 (12%)

Query: 6    ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEAR--GSRQE 63
            EL LQE+S+R +  +     +     E + +        +++ I +   +E +  G ++ 
Sbjct: 1580 ELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRR 1639

Query: 64   LVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE 123
            L E + +   R V  E QR     E        Q+S++       +  ALQ +V      
Sbjct: 1640 LKEVLDASESRTVKLELQRRSLEGE-------LQRSRLGLSDREAQAQALQDRV------ 1686

Query: 124  RDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEART 183
                    DS QR+++ S V+  +L+  V  L   + ++      L+ +  G+ +  A++
Sbjct: 1687 --------DSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQS 1738

Query: 184  REPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPAPPS 243
                   + + + +       + D         Q+L +    + + L ++ + SS     
Sbjct: 1739 SASLNSTRDKNLHLQKALTACEHD--------RQVLQERLDAARQALSEARKQSSSLGEQ 1790

Query: 244  QQSLYKRVAE 253
             Q+L   VA+
Sbjct: 1791 VQTLRGEVAD 1800



 Score = 32.3 bits (72), Expect = 0.86
 Identities = 24/99 (24%), Positives = 45/99 (45%), Gaps = 5/99 (5%)

Query: 121  QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 180
            Q+ERD+  +   +  R++++   E+DS   +  +L   V E     R +     GV  + 
Sbjct: 1522 QRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAEL 1581

Query: 181  ARTREPCPR-EKQRLVRMHAICPRDDSDCSLVSSTESQL 218
            A   E   R E++R   +  +   + S    + +TES+L
Sbjct: 1582 ALQEESVRRSERERRATLDQVATLERS----LQATESEL 1616


>gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
          Length = 636

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 50/215 (23%), Positives = 95/215 (44%), Gaps = 35/215 (16%)

Query: 6   ELELQEQSLRTASDQ--ESGDEELNRLKEENEKLRSLTFSLAEKD--------------- 48
           +L  + ++L+   D+  E  D+   RL+EEN +L+ L  S   K+               
Sbjct: 214 QLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRPGSPKMEGTG 273

Query: 49  ---ILEQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQL 105
              +  Q        +   V  + +  ++    E+QR +  E  +Q    F+  K   Q 
Sbjct: 274 KKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMK---QQ 330

Query: 106 YREKVNALQAQVCELQKERDQAYSARDSAQRE------ISQSLVEKDSLRRQVFELTDQV 159
           Y +K+  L+ ++ +LQK+     + R+  QR+      +++S +E +   ++  +LT + 
Sbjct: 331 YEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKE--QLTAEA 388

Query: 160 CELRTQLRQLQAEPPGVLKQEARTREPCPREKQRL 194
            ELR +++ LQ +    L    R RE   +E QRL
Sbjct: 389 KELRQKVKYLQDQ----LSPLTRQREYQEKEIQRL 419



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 40/188 (21%), Positives = 83/188 (44%), Gaps = 29/188 (15%)

Query: 24  DEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAAERQRE 83
           D E  R +++ +  R L  + ++ ++ E   ++     +EL +++  L+++     RQRE
Sbjct: 351 DLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQRE 410

Query: 84  QYWEEKEQTLLQFQKSKMACQ------------------LYREKVNALQAQVCELQKERD 125
            Y E++ Q L +  +  ++ Q                  L R++    Q ++ + Q +  
Sbjct: 411 -YQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIF 469

Query: 126 QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185
           +    R+ + RE      EK+ L++QV +L  QV     QL+          K E + RE
Sbjct: 470 EEDFQRERSDRERMNE--EKEELKKQVEKLQAQVTLSNAQLK--------AFKDEEKARE 519

Query: 186 PCPREKQR 193
              ++K++
Sbjct: 520 ALRQQKRK 527



 Score = 29.3 bits (64), Expect = 7.3
 Identities = 32/137 (23%), Positives = 58/137 (42%), Gaps = 9/137 (6%)

Query: 9   LQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARG--SRQELVE 66
           LQ+Q       +E  ++E+ RL +  E+  S+    +       S + A     +QELV 
Sbjct: 398 LQDQLSPLTRQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVT 457

Query: 67  RIHSLRERAVAAERQ-------REQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCE 119
           +   L+++    E         RE+  EEKE+   Q +K +    L   ++ A + +   
Sbjct: 458 QNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKA 517

Query: 120 LQKERDQAYSARDSAQR 136
            +  R Q   A+ S +R
Sbjct: 518 REALRQQKRKAKASGER 534


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 35/165 (21%), Positives = 78/165 (47%), Gaps = 13/165 (7%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
           E + QEQ  +    +E   E+  +++E+ EK+R     + E++ + Q  +E  G ++E  
Sbjct: 597 EEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEE-- 654

Query: 66  ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125
                + E+    + Q E  W ++E+   Q +K +   +  RE+   +Q Q  ++ ++ +
Sbjct: 655 ----KMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 710

Query: 126 QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ 170
           +     +  Q        +++ +RRQ  ++ +Q   LR Q  ++Q
Sbjct: 711 KMCEQEEKMQE-------QEEKMRRQEEKMWEQEVRLRQQEEKMQ 748



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 39/193 (20%), Positives = 88/193 (45%), Gaps = 20/193 (10%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
           E ++QE   +    +E   E+  +++E+ EK+R     + EK+   +  +E    ++E +
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365

Query: 66  ERIHSLR-ERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKER 124
            R   +  E+     RQ E  WE++                  EK+  L+ ++ E +K R
Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEKE------------------EKIRELEEKMHEQEKIR 407

Query: 125 DQAYSARDSAQ-REISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEART 183
           +Q    ++  + RE  +   ++  + RQ  ++ +Q  ++R Q +++  +   + +QE   
Sbjct: 408 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 467

Query: 184 REPCPREKQRLVR 196
            E   +E++ + R
Sbjct: 468 EEEKRQEQEEMWR 480



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 32/177 (18%), Positives = 89/177 (50%), Gaps = 6/177 (3%)

Query: 10  QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIH 69
           QE+ +R   +    +E+++    E EK+        ++D + +  ++ R   +++  +  
Sbjct: 536 QEEKIREQEEMWREEEKMH----EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEE 591

Query: 70  SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYS 129
            +RE+    + Q E+ W+++E+   Q +K +   +  RE+   ++ Q  E+ +E+++   
Sbjct: 592 KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQE-EMTQEQEEKMG 650

Query: 130 ARDSAQREISQSLVE-KDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185
            ++    E  + + E ++++ RQ  ++ +Q  ++R Q  +++ +   + +QE +  E
Sbjct: 651 EQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 707



 Score = 37.7 bits (86), Expect = 0.021
 Identities = 32/184 (17%), Positives = 81/184 (44%), Gaps = 7/184 (3%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
           E ++ EQ      ++    EE+ R   + EK+        +K+ + +  ++ R   +++ 
Sbjct: 457 EEKIHEQEKIREEEKRQEQEEMWR---QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVW 513

Query: 66  ERIHSLRERAVAAERQREQYWEE----KEQTLLQFQKSKMACQLYREKVNALQAQVCELQ 121
            +   +RE+      Q E+ W +    +EQ  +  ++ KM  Q    +    Q Q  ++ 
Sbjct: 514 RQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMW 573

Query: 122 KERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEA 181
           ++ ++     +   R+  +   +++  + Q  ++  Q  ++R Q  ++Q +   + +QE 
Sbjct: 574 RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEE 633

Query: 182 RTRE 185
           + RE
Sbjct: 634 KIRE 637



 Score = 37.4 bits (85), Expect = 0.027
 Identities = 33/189 (17%), Positives = 88/189 (46%), Gaps = 29/189 (15%)

Query: 19  DQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERI----HSLRER 74
           ++E   E+ +++  + EK+R     +  +   E+ + E    RQE  E++      +RE+
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQ---EEKIREQEEKRQEQEEKMWKQEEKIREQ 617

Query: 75  AVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCE----LQKERDQAYSA 130
               + Q E+  E++E    + ++ +   Q   EK+   + ++CE    +Q++ +  +  
Sbjct: 618 EEKIQEQEEKIREQEE----KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673

Query: 131 RDSAQREISQSLVEKDSLRRQ----------VFELTDQVCE----LRTQLRQLQAEPPGV 176
            +  + +  +   +++ +R Q          ++E  +++CE    ++ Q  +++ +   +
Sbjct: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733

Query: 177 LKQEARTRE 185
            +QE R R+
Sbjct: 734 WEQEVRLRQ 742



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 34/181 (18%), Positives = 80/181 (44%), Gaps = 6/181 (3%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSL---AEKDILEQSLDEARGSRQEL 64
           +LQE+     S++      +  LK + E+ + L       AE D L + L       Q  
Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284

Query: 65  VERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKER 124
           VE  + L  R    ++Q E+ W ++E+     +K +   +  RE+   ++ Q  +++++ 
Sbjct: 285 VEE-NELWNRL--NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341

Query: 125 DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTR 184
           +  +   +  +R+      +++ +RRQ   + ++  ++R Q   +  +   + + E +  
Sbjct: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 401

Query: 185 E 185
           E
Sbjct: 402 E 402


>gi|4506467 radixin [Homo sapiens]
          Length = 583

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 35/186 (18%), Positives = 88/186 (47%), Gaps = 22/186 (11%)

Query: 9   LQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERI 68
           ++ Q ++  + +E   ++L R + ENEK +        ++I E+  +     ++EL+ER+
Sbjct: 300 IEVQQMKAQAREEKHQKQLERAQLENEKKK--------REIAEKEKERIEREKEELMERL 351

Query: 69  HSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAY 128
             + E+ + A+++ E             ++++ A +L +E+  A + +   L+KER  A 
Sbjct: 352 KQIEEQTIKAQKELE-------------EQTRKALELDQERKRA-KEEAERLEKERRAAE 397

Query: 129 SARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCP 188
            A+ +  ++ +  +  ++ L  ++ E T ++  L    ++ + E      +    +E   
Sbjct: 398 EAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLE 457

Query: 189 REKQRL 194
           + K+ L
Sbjct: 458 KTKEEL 463


>gi|219521893 coiled-coil transcriptional coactivator isoform 2
           [Homo sapiens]
          Length = 606

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 51/196 (26%), Positives = 86/196 (43%), Gaps = 29/196 (14%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEK-DILEQSLDEARGSRQELVE 66
           +L  Q     +D+E  + EL  LKE+    + L  S  +K  +L + L  A  +R   + 
Sbjct: 234 KLLGQLKEVQADKEQSEAELEPLKEQLRGAQELAASSQQKATLLGEELASAAAARDRTIA 293

Query: 67  RIHSLRERAVAAE------------RQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQ 114
            +H  R R   AE            ++ +  W ++   LLQ  +++      ++K+  L 
Sbjct: 294 ELH--RSRLEVAEVNGRLAELGLHLKEEKCQWSKERAGLLQSVEAE------KDKILKLS 345

Query: 115 AQVCELQK----ERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ 170
           A++  L+K    ER Q    +    RE   SLV+    +R++ EL   +  L+ +  QLQ
Sbjct: 346 AEILRLEKAVQEERTQNQVFKTELAREKDSSLVQLSESKRELTELRSALRVLQKEKEQLQ 405

Query: 171 AEPPGVL----KQEAR 182
            E   +L    K EAR
Sbjct: 406 EEKQELLEYMRKLEAR 421



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 31/148 (20%), Positives = 63/148 (42%), Gaps = 7/148 (4%)

Query: 32  EENEKLRSLTFSLAEKDILEQSLDEARGSRQELVE-------RIHSLRERAVAAERQREQ 84
           EE +    +   + +  +L+  LDE++  R +L++       ++  LR R    ER    
Sbjct: 98  EEADGGSDILLVVPKATVLQNQLDESQQERNDLMQLKLQLEGQVTELRSRVQELERALAT 157

Query: 85  YWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVE 144
             +E  + + Q++    +     E+ + L  Q  +      +      +   ++    VE
Sbjct: 158 ARQEHTELMEQYKGISRSHGEITEERDILSRQQGDHVARILELEDDIQTISEKVLTKEVE 217

Query: 145 KDSLRRQVFELTDQVCELRTQLRQLQAE 172
            D LR  V  LT +  +L  QL+++QA+
Sbjct: 218 LDRLRDTVKALTREQEKLLGQLKEVQAD 245


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 47/181 (25%), Positives = 77/181 (42%), Gaps = 19/181 (10%)

Query: 20  QESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAAE 79
           QE   +    L+EE E+LR L      ++  E+   + R  R++ + R      R    E
Sbjct: 261 QEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE 320

Query: 80  R-----QREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSA 134
           R     +REQ  E +EQ L + Q+ +   QL RE+           ++ER +    R+  
Sbjct: 321 RREQQERREQQEERREQQLRREQEERREQQLRREQ-----------EEERREQQLRREQE 369

Query: 135 QREISQSLVEKDSLRRQVFELTDQVCELRTQLR---QLQAEPPGVLKQEARTREPCPREK 191
           +    Q L  +  LRR+     +Q      QLR   QL+ E     +Q+ R  +   RE+
Sbjct: 370 EERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 429

Query: 192 Q 192
           +
Sbjct: 430 E 430



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 64/263 (24%), Positives = 110/263 (41%), Gaps = 34/263 (12%)

Query: 7   LELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVE 66
           L+L+E+  R    QE  +++L R +EE  + R       E++ L+Q L   +  R+E  E
Sbjct: 489 LKLEEEERR--EQQERREQQLRREQEERREQRLKRQE--EEERLQQRLRSEQQLRREQEE 544

Query: 67  RIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYRE------KVNALQAQVCEL 120
           R    RE+ +  E ++    E +EQ L + Q+ +    L RE      ++   Q +  E 
Sbjct: 545 R----REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ 600

Query: 121 QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 180
           + +R++        +RE      E +  RRQ    +++  E R Q  QL+ E     +Q 
Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ--QLRREQQERREQR 658

Query: 181 ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDS------F 234
            +  E   R +QRL R H                  Q L++     +RE + S      +
Sbjct: 659 LKREEEEERLEQRLKREHE------------EERREQELAEEEQEQARERIKSRIPKWQW 706

Query: 235 RSSSPAPPSQQSLYKRVAEDFGE 257
           +  S A   Q  +Y R  +  G+
Sbjct: 707 QLESEADARQSKVYSRPRKQEGQ 729



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 56/207 (27%), Positives = 101/207 (48%), Gaps = 25/207 (12%)

Query: 10   QEQSLRTASDQESGDEELNRLKEENEKLRSLTF--SLAEKDILEQSLDEARGSRQELVER 67
            QE+  +   ++E   EE   L+EE EK R   +     +KD L+Q  +E +  R+E  +R
Sbjct: 984  QEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ--EEEQLLREEREKR 1041

Query: 68   IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYRE--KVNALQAQVCEL----- 120
                RER     R+ E+  +E+EQ L + ++++   +L R+  K   LQ +  +L     
Sbjct: 1042 RLQERERQY---REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098

Query: 121  ----QKERDQAYSARDSAQREISQSL-VEKDSLRRQVFELT-DQVCELRTQLRQLQAEPP 174
                ++ER++     +  Q+E  Q L  E++  RRQ  E    +  E++ +  QL  E P
Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEP 1158

Query: 175  -----GVLKQEARTREPCPREKQRLVR 196
                   L+++ R  E   +E+++L+R
Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLR 1185



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 51/214 (23%), Positives = 89/214 (41%), Gaps = 23/214 (10%)

Query: 6   ELELQEQSLRTASDQESGDEELNR---------------LKEENEKLRSLTFSLAEKDIL 50
           E E +EQ LR   ++E  +++L R               L+ E +  R       ++   
Sbjct: 356 EEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 415

Query: 51  EQSLDEARGSRQELVERIHSL------RERAVAAERQREQYWEEKEQTLLQFQKSKMACQ 104
           EQ L   +  R+E  E  H        RE+ +  E++  + W ++E+   + ++ +   Q
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475

Query: 105 LYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFE-LTDQVCELR 163
           L R++    + +  +L++E  +    R   Q    Q    +  L+RQ  E    Q     
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535

Query: 164 TQLRQLQAEP-PGVLKQEARTREPCPREKQRLVR 196
            QLR+ Q E    +LK+E   R    R +QRL R
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKR 569



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 59/267 (22%), Positives = 109/267 (40%), Gaps = 38/267 (14%)

Query: 6    ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
            EL+ +E+  R   +QE    E  +L++E E+L         +   E+   + +  +Q+  
Sbjct: 912  ELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEE 971

Query: 66   ERIHSLRERAVAAERQR----EQYWEEKEQTLLQFQKSKMACQ----LYREKVNALQAQV 117
            + +    E+    ER++    E+  +++E+ LL+ ++ K   Q     YR+K    Q + 
Sbjct: 972  QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEE 1031

Query: 118  CELQ--------KERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLR-- 167
              L+        +ER++ Y   +  Q+E  Q L E+   RR+         EL  Q R  
Sbjct: 1032 QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQ--------ELERQYRKE 1083

Query: 168  -QLQAEPPGVLKQEARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATS 226
             +LQ E   +L++E   R    RE+Q        C  ++    L    E  L  +     
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERERQ--------CREEE---ELQQEEEQLLREEREKRR 1132

Query: 227  SRELVDSFRSSSPAPPSQQSLYKRVAE 253
             +EL   +R        ++ L +   E
Sbjct: 1133 RQELERQYREEEEVQQEEEQLLREEPE 1159



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 42/185 (22%), Positives = 84/185 (45%), Gaps = 8/185 (4%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
           E ++Q  R   D+   +EE    ++    LR       E++ L++   + +   QE  E+
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRK------EEEKLQEEEPQRQRELQEEEEQ 277

Query: 68  IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127
           +  L  + +  ERQ E+  +++ +   Q ++ +   +  +++    Q +  E Q+ER + 
Sbjct: 278 LRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQ 337

Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPC 187
              R+  +R   Q   E++  RR+     +Q  E R Q  QL+ E     +Q+ R  +  
Sbjct: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEERREQ--QLRREQQLRREQQLRREQQL 395

Query: 188 PREKQ 192
            RE+Q
Sbjct: 396 RREQQ 400



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 43/174 (24%), Positives = 80/174 (45%), Gaps = 6/174 (3%)

Query: 9    LQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERI 68
            LQE+  +   ++E   EE   L EE E  R        +   E   +E +  R+E  +R 
Sbjct: 1043 LQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102

Query: 69   HSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAY 128
               RER     R+ E+  +E+EQ L + ++ +   +L R+     + Q  E Q  R++  
Sbjct: 1103 RQERERQC---REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE 1159

Query: 129  SARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEAR 182
              R   ++E+ +   E++ L+++  +L  +  E R Q R+ Q      L+++ R
Sbjct: 1160 KRR---RQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKR 1210



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 50/189 (26%), Positives = 84/189 (44%), Gaps = 21/189 (11%)

Query: 20   QESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAAE 79
            QE   +E   L+EE E+L+        +   E+   E    +QE  + +   RE+    E
Sbjct: 896  QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE 955

Query: 80   RQR----EQYWEEKEQTLLQFQKSKMACQ----LYREKVNALQAQVCELQKER------- 124
            R+R    ++  ++KE+ LL  +  K   Q     YRE+    Q +   L++ER       
Sbjct: 956  RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE 1015

Query: 125  -DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEART 183
             ++ Y  +D  Q+E  Q L E+   RR    L ++  + R +  +LQ E   +L +E  T
Sbjct: 1016 WERQYRKKDELQQEEEQLLREEREKRR----LQERERQYREE-EELQQEEEQLLGEERET 1070

Query: 184  REPCPREKQ 192
            R     E+Q
Sbjct: 1071 RRRQELERQ 1079



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 51/186 (27%), Positives = 82/186 (44%), Gaps = 19/186 (10%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSR-QELVE 66
           E +E+ LR    Q+     L   +E+ ++ R       E   LE+     R  R Q+L E
Sbjct: 792 EQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE 851

Query: 67  RIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQ 126
               L+E      R +EQ  ++K +  L+ ++ +    LY +   ALQ Q   L+KE+  
Sbjct: 852 EEDGLQEDQ-ERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKP--ALQEQ---LRKEQQL 905

Query: 127 AYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREP 186
                +  QRE      E++  RRQ     +Q  + R +  QLQ E   +L++E   R  
Sbjct: 906 LQEEEEELQRE------EREKRRRQ-----EQERQYREE-EQLQQEEEQLLREEREKRRR 953

Query: 187 CPREKQ 192
             RE+Q
Sbjct: 954 QERERQ 959



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 56/220 (25%), Positives = 96/220 (43%), Gaps = 22/220 (10%)

Query: 11   EQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHS 70
            EQ LR    Q+   +E +R   E+E+L      L E++  EQ L      R+ L E    
Sbjct: 1601 EQQLRRQEGQQQLRQERDRKFREDEQL------LQERE--EQQLHRQERDRKFLEEEPQL 1652

Query: 71   LR-ERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYS 129
             R ER       R++ + E+EQ L + ++ ++  Q    K    + Q+   ++ER     
Sbjct: 1653 RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQE 1712

Query: 130  ARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPR 189
             +   ++E+ +   E++ LR++    T+Q  +LR Q R  +     +L++E    E   R
Sbjct: 1713 EQQLRRQELERKFREEEQLRQE----TEQE-QLRRQERYRK-----ILEEEQLRPE---R 1759

Query: 190  EKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRE 229
            E+Q+L R        + +       E QL S  S    RE
Sbjct: 1760 EEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE 1799



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 54/220 (24%), Positives = 95/220 (43%), Gaps = 34/220 (15%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDIL--------EQSLDEA 57
           E + ++Q      D++  DEEL R ++E ++        AE++ L        E+  DE 
Sbjct: 152 EEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERR---AEEEQLQSCKGHETEEFPDEE 208

Query: 58  RGSRQELVERIHSLRERAVAAERQR---------EQYWEEKEQTL------LQFQKSKMA 102
           +  R+EL+E     RE      R+R         E+ W ++E  L      LQ ++ +  
Sbjct: 209 QLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ 268

Query: 103 CQLYREKVNALQAQVCELQKERDQAYSARDSAQRE------ISQSLVEKDSLRRQVFELT 156
            +L  E+    + +  EL++ER +    +   +RE        +   E+   RR+  E  
Sbjct: 269 RELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERR 328

Query: 157 DQVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLVR 196
           +Q  E R Q  QL+ E     +Q+ R  +   R +Q+L R
Sbjct: 329 EQQEERREQ--QLRREQEERREQQLRREQEEERREQQLRR 366



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 48/188 (25%), Positives = 84/188 (44%), Gaps = 15/188 (7%)

Query: 10  QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARG--SRQELVER 67
           +EQ LR   +Q+   E+  R ++E E+          +  L++  +E R    R+E  ER
Sbjct: 409 REQQLRR--EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER 466

Query: 68  IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127
            H    R    +R +E+  E +E+ L      K+  +  RE+    + Q+   Q+ER + 
Sbjct: 467 -HEQERRKQQLKRDQEE--ERRERWL------KLEEEERREQQERREQQLRREQEERREQ 517

Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVC--ELRTQLRQLQAEPPGVLKQEARTRE 185
              R   +  + Q L  +  LRR+  E  +Q+   E   +L Q + E     +QE R  +
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ 577

Query: 186 PCPREKQR 193
              RE++R
Sbjct: 578 LLKREEER 585



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 55/203 (27%), Positives = 85/203 (41%), Gaps = 18/203 (8%)

Query: 8   ELQEQSLRTASDQESGD------EELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGS- 60
           +L+ Q LR    +E         E+  R K+E E+         +++  EQ  +E R   
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQ-EERREQQ 338

Query: 61  -RQELVERIHSLRERAVAAER-----QREQYWEEKEQTLLQFQKSKMACQLYREKVNALQ 114
            R+E  ER      R    ER     +REQ  E +EQ L + Q+ +   QL RE+    +
Sbjct: 339 LRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRRE 398

Query: 115 AQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPP 174
            Q+   Q+ R +    R+   R   Q   E++  R    E   +      +L++ Q E  
Sbjct: 399 QQLRREQQLRREQQLRREQQLRREQQLRREQEEERH---EQKHEQERREQRLKREQEERR 455

Query: 175 GVLKQEART-REPCPREKQRLVR 196
             LK+E  T R    R KQ+L R
Sbjct: 456 DWLKREEETERHEQERRKQQLKR 478



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 42/184 (22%), Positives = 86/184 (46%), Gaps = 20/184 (10%)

Query: 7    LELQEQSLRTASDQESGDEELNRLKEENEKLRSLTF--SLAEKDILEQSLDEARGSRQEL 64
            L+ ++Q  R   +++  +EE  R + E E+LR       + E++ L    +E +  RQE 
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER 1769

Query: 65   ------VERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQL------YREKVNA 112
                   E++   RE      ++ ++ + E+EQ   + ++ ++  Q       + E+   
Sbjct: 1770 DRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQ 1829

Query: 113  LQAQVCELQKERDQAYSA------RDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQL 166
            L+ Q   L++ERD+ Y A      ++ ++RE  +   E++  RRQ  E   +   +R Q 
Sbjct: 1830 LEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQ 1889

Query: 167  RQLQ 170
            ++ Q
Sbjct: 1890 KEEQ 1893



 Score = 37.0 bits (84), Expect = 0.035
 Identities = 45/187 (24%), Positives = 75/187 (40%), Gaps = 14/187 (7%)

Query: 7   LELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVE 66
           LE + +  R   +QE   ++L + +EE  + R       +++ LEQ L      R E  E
Sbjct: 558 LEQERREQRLKREQEERRDQLLKREEERRQQR---LKREQEERLEQRLKREEVERLEQEE 614

Query: 67  RIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQ 126
           R     +R    E +R+Q  + +EQ   + Q+ +   Q  RE     Q    E ++ER +
Sbjct: 615 RREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE-----QRLKREEEEERLE 669

Query: 127 AYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREP 186
               R+  +    Q L E++       E   +  + R    Q Q E     +Q      P
Sbjct: 670 QRLKREHEEERREQELAEEEQ------EQARERIKSRIPKWQWQLESEADARQSKVYSRP 723

Query: 187 CPREKQR 193
             +E QR
Sbjct: 724 RKQEGQR 730



 Score = 37.0 bits (84), Expect = 0.035
 Identities = 46/194 (23%), Positives = 91/194 (46%), Gaps = 23/194 (11%)

Query: 6    ELELQEQSLRTASDQESGDEE--LNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQE 63
            +LE +EQ      D++S +E+  L   +EE  + +       E++ L Q  +E    RQE
Sbjct: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357

Query: 64   LVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKE 123
               R    RE  +  + Q  ++ EE+++   Q ++ K    L  E+    Q +  +L+++
Sbjct: 1358 ---RDRKFREEELRHQEQGRKFLEEEQRLRRQERERKF---LKEEQQLRCQEREQQLRQD 1411

Query: 124  RDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ-AEPPGVLKQEAR 182
            RD+ +       RE  Q L  ++  R+      ++  ++R Q R+ +  E    L+QE  
Sbjct: 1412 RDRKF-------REEEQQLSRQERDRK----FREEEQQVRRQERERKFLEEEQQLRQERH 1460

Query: 183  TREPCPREKQRLVR 196
             +    RE+++L++
Sbjct: 1461 RKF---REEEQLLQ 1471



 Score = 36.6 bits (83), Expect = 0.046
 Identities = 45/196 (22%), Positives = 80/196 (40%), Gaps = 17/196 (8%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLD-------EAR 58
           E  L+ + +     +E  ++ L R + E E+ + L  S  +++  +Q L        E R
Sbjct: 599 EQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQR 658

Query: 59  GSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVC 118
             R+E  ER+    +R    ER+ ++  EE+++   +  KS++    ++ +  A   Q  
Sbjct: 659 LKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSK 718

Query: 119 ELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLK 178
              + R Q    R   Q E           RR+  EL  Q  E R   +Q + E      
Sbjct: 719 VYSRPRKQEGQRRRQEQEE---------KRRRRESELQWQE-EERAHRQQQEEEQRRDFT 768

Query: 179 QEARTREPCPREKQRL 194
            + +  E   R +QRL
Sbjct: 769 WQWQAEEKSERGRQRL 784



 Score = 36.6 bits (83), Expect = 0.046
 Identities = 50/198 (25%), Positives = 91/198 (45%), Gaps = 24/198 (12%)

Query: 7    LELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVE 66
            LE +EQ  R    Q+  +EE + L+E+ E+ RS      +K      L+E R  R+  + 
Sbjct: 834  LEEEEQLQRRERAQQLQEEE-DGLQEDQERRRSQEQRRDQK--WRWQLEEERKRRRHTLY 890

Query: 67   RIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQ----LYREKVNALQAQVCEL-- 120
               +L+E+     R+ +Q  +E+E+ L + ++ K   Q     YRE+    Q +   L  
Sbjct: 891  AKPALQEQL----RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946

Query: 121  ------QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPP 174
                  ++ER++ Y      Q++  Q L E+   RR+     ++  + R +  +LQ E  
Sbjct: 947  EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR----QEREKKYREE-EELQQEEE 1001

Query: 175  GVLKQEARTREPCPREKQ 192
             +L++E   R     E+Q
Sbjct: 1002 QLLREEREKRRRQEWERQ 1019



 Score = 36.6 bits (83), Expect = 0.046
 Identities = 50/205 (24%), Positives = 89/205 (43%), Gaps = 28/205 (13%)

Query: 6    ELELQEQSLRTASDQESGD-------EELNRLKE--------ENEKLRSLTFSLAEKDIL 50
            EL+ Q++  R   + +  D       E+ N +++        ENE+ R L  S       
Sbjct: 1204 ELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQS 1263

Query: 51   EQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKV 110
            +Q L    G +QE        RE+     +QR++++ E+EQ   + QK        R++ 
Sbjct: 1264 QQDLQHLLGEQQERD------REQERRRWQQRDRHFPEEEQLEREEQKEAKR----RDRK 1313

Query: 111  NALQAQVCELQKERDQAYSARDSAQREISQSLVEKDS--LRRQVFELTDQVCELRTQLRQ 168
            +  + Q+   ++E  +     D   RE  Q L E++   LRRQ  +   +  ELR Q + 
Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG 1373

Query: 169  LQ-AEPPGVLKQEARTREPCPREKQ 192
             +  E    L+++ R R+    E+Q
Sbjct: 1374 RKFLEEEQRLRRQERERKFLKEEQQ 1398



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 49/224 (21%), Positives = 93/224 (41%), Gaps = 29/224 (12%)

Query: 6    ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
            E++ +E+ L     ++   +EL R   E E+L+            EQ L E +  R++  
Sbjct: 1145 EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE---------EQLLREEQEKRRQ-- 1193

Query: 66   ERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125
            ER    RE      ++R+Q + +++      Q+S +  Q   EK NA++      +   +
Sbjct: 1194 ERERQYREEEELQRQKRKQRYRDED------QRSDLKWQWEPEKENAVRDNKVYCKGREN 1247

Query: 126  QAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLR--------QLQAEPPGVL 177
            + +   + +Q    QS  +   L  +  E   +    R Q R        QL+ E     
Sbjct: 1248 EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREE---- 1303

Query: 178  KQEARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSD 221
            ++EA+ R+   +E+++L+R      R   +       E QLL +
Sbjct: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQE 1347



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 45/185 (24%), Positives = 82/185 (44%), Gaps = 12/185 (6%)

Query: 8    ELQEQSL-RTASDQESGDEELN-RLKEENEKLRS--LTFSLAEKDILEQSLDEARGSRQ- 62
            E +EQ L R   D++  +EE   R +E + K R   L     E+  LE+     R  RQ 
Sbjct: 1472 EREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531

Query: 63   ELVERIHSLR--ERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL 120
            + ++    LR  ER     + R++ + E+EQ   + ++ +++ Q    K    + +V   
Sbjct: 1532 KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQ 1591

Query: 121  QKER----DQAYSARDSAQREISQSLVEKDSLRRQVF-ELTDQVCELRTQLRQLQAEPPG 175
            ++ER    D+    R   Q+++ Q    K     Q+  E  +Q    + + R+   E P 
Sbjct: 1592 EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQ 1651

Query: 176  VLKQE 180
            + +QE
Sbjct: 1652 LRRQE 1656



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 49/192 (25%), Positives = 83/192 (43%), Gaps = 23/192 (11%)

Query: 6    ELELQEQSLRTASDQES---GDEELNRLKEENE-KLRSLTFSLAEKDILEQSLDEARGSR 61
            EL  QEQ  +   +++     + E   LKEE + + +     L +    +   +E + SR
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425

Query: 62   QELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQ 121
            QE   +     ++    ER+R+    E+EQ L Q +  K     +RE+   LQ       
Sbjct: 1426 QERDRKFREEEQQVRRQERERKFL--EEEQQLRQERHRK-----FREEEQLLQ------- 1471

Query: 122  KERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ-AEPPGVLKQE 180
             ER++    R    R+    L E+  LRRQ  +   +  ELR+Q  + +  E    L ++
Sbjct: 1472 -EREEQQLHRQERDRKF---LEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQ 1527

Query: 181  ARTREPCPREKQ 192
             R R+    E+Q
Sbjct: 1528 QRQRKFLQEEQQ 1539


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 46/201 (22%), Positives = 98/201 (48%), Gaps = 14/201 (6%)

Query: 6    ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDIL----EQSLDEARGSR 61
            +L+L ++S+  A+  +   EE  +LK+++ +L  L+  + ++ +L    ++ + E +   
Sbjct: 1107 DLKLTQESVADAAQDKQQLEE--KLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARA 1164

Query: 62   QELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQ 121
            +EL E + + R      E+QR +   E E+   + +++  A    RE     +A++  L+
Sbjct: 1165 EELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLR 1224

Query: 122  KERDQA-------YSARDSAQREISQSLVEK-DSLRRQVFELTDQVCELRTQLRQLQAEP 173
            +E ++A        +A    Q E +  L E+ DSL+R   +L  +  ELR ++  L A  
Sbjct: 1225 RELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANV 1284

Query: 174  PGVLKQEARTREPCPREKQRL 194
              + + +A   + C   + +L
Sbjct: 1285 ETLTRAKASAEKLCRTYEDQL 1305



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 39/170 (22%), Positives = 71/170 (41%), Gaps = 16/170 (9%)

Query: 7    LELQEQSLRTASDQESGDEELNRLK------EENEKLRSLTFSLAEKDILEQSLDEARGS 60
            LE ++  ++ A ++  G  EL   K      E ++    +   LAEKD      +E    
Sbjct: 1582 LEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKD------EECANL 1635

Query: 61   RQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCE- 119
            R+     + SL+    A  R R +    K++  ++   + +  QL      A +AQ    
Sbjct: 1636 RRNHQRAVESLQASLDAETRARNEALRLKKK--MEGDLNDLELQLGHATRQATEAQAATR 1693

Query: 120  -LQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQ 168
             +Q +  +  + RD  QR  ++   +  +L R+   L  ++ ELR  L Q
Sbjct: 1694 LMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQ 1743



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 48/233 (20%), Positives = 102/233 (43%), Gaps = 31/233 (13%)

Query: 4    SCELELQEQSL-RTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQ 62
            + EL  Q Q+L R AS   +  EEL    E+ E+ R L    AE+++LE +         
Sbjct: 1713 AAELHEQAQALERRASLLAAELEELRAALEQGERSRRL----AEQELLEAT--------- 1759

Query: 63   ELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVN------ALQAQ 116
               ER++ L  +      Q+++   +  Q   + +++    +   EK        A+ A+
Sbjct: 1760 ---ERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAE 1816

Query: 117  VCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELT-----DQVCELRTQLRQLQA 171
              EL+KE+D + +  +  ++ + Q++ E  +   +  +        QV +L  ++R+L+A
Sbjct: 1817 --ELKKEQDTS-AHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEA 1873

Query: 172  EPPGVLKQEARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSA 224
            E     K+ A   +   + ++R+  +      D  + + +     +L S + +
Sbjct: 1874 ELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKS 1926


>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
          Length = 1139

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 46/220 (20%), Positives = 92/220 (41%), Gaps = 16/220 (7%)

Query: 10  QEQSLRTASDQESGDEELNRLK--EENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
           +E+ LR          E  RLK  E+  KL+ L     + + +++   + +  + +L  R
Sbjct: 82  EEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRR 141

Query: 68  IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127
           +   R+ A  A   +E+Y EE   T    + + +  ++  E+  +LQ +V E  KER   
Sbjct: 142 LKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV-EALKER--- 197

Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPC 187
                     + +   + + L+ ++ E          QL+QL+ +   +     R R+  
Sbjct: 198 ----------VDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLS 247

Query: 188 PREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSS 227
             EKQ  V++  +  + + +  +V     +L  +LS   S
Sbjct: 248 SSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAES 287



 Score = 36.6 bits (83), Expect = 0.046
 Identities = 56/264 (21%), Positives = 100/264 (37%), Gaps = 53/264 (20%)

Query: 19   DQESGDEELNR-LKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVA 77
            D+E+  +EL + LK + E+L      L+   +LE+ LD A     E +E++ +  E   A
Sbjct: 813  DRETVIKELKKSLKIKGEELSEANVRLS---LLEKKLDSAAKDADERIEKVQTRLEETQA 869

Query: 78   AERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQRE 137
              R++E+ +E                    E ++ALQA + +L+ E+ +     +S  + 
Sbjct: 870  LLRKKEKEFE--------------------ETMDALQADIDQLEAEKAELKQRLNSQSKR 909

Query: 138  ISQSL---------------------------VEKDSLRRQVFELTDQVCELRTQLRQLQ 170
              + L                           V    L +    L  Q+  +R  + QLQ
Sbjct: 910  TIEGLRGPPPSGIATLVSGIAGGAIPGQAPGSVPGPGLVKDSPLLLQQISAMRLHISQLQ 969

Query: 171  AEPPGVLKQEARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSR-E 229
             E   +LK               + ++    P  +     +    SQLL  L+  S+   
Sbjct: 970  HE-NSILKGAQMKASLASLPPLHVAKLSHEGPGSELPAGALYRKTSQLLETLNQLSTHTH 1028

Query: 230  LVDSFRSSSPAPPSQQSLYKRVAE 253
            +VD  R+S  A      L ++VA+
Sbjct: 1029 VVDITRTSPAAKSPSAQLMEQVAQ 1052



 Score = 30.0 bits (66), Expect = 4.3
 Identities = 25/118 (21%), Positives = 55/118 (46%), Gaps = 3/118 (2%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
           EL+EQ       +E  +   +R     EK+R L  ++ + + + +  DE + + +E    
Sbjct: 291 ELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELE 350

Query: 68  IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125
           +    + A A  R+ ++  E  ++T+  +Q++    + YR+    LQ    EL  +++
Sbjct: 351 LREQLDMAGARVREAQKRVEAAQETVADYQQT---IKKYRQLTAHLQDVNRELTNQQE 405


>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
          Length = 1253

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 46/220 (20%), Positives = 92/220 (41%), Gaps = 16/220 (7%)

Query: 10  QEQSLRTASDQESGDEELNRLK--EENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
           +E+ LR          E  RLK  E+  KL+ L     + + +++   + +  + +L  R
Sbjct: 196 EEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRR 255

Query: 68  IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127
           +   R+ A  A   +E+Y EE   T    + + +  ++  E+  +LQ +V E  KER   
Sbjct: 256 LKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV-EALKER--- 311

Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPC 187
                     + +   + + L+ ++ E          QL+QL+ +   +     R R+  
Sbjct: 312 ----------VDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLS 361

Query: 188 PREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSS 227
             EKQ  V++  +  + + +  +V     +L  +LS   S
Sbjct: 362 SSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAES 401



 Score = 36.6 bits (83), Expect = 0.046
 Identities = 56/264 (21%), Positives = 100/264 (37%), Gaps = 53/264 (20%)

Query: 19   DQESGDEELNR-LKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVA 77
            D+E+  +EL + LK + E+L      L+   +LE+ LD A     E +E++ +  E   A
Sbjct: 927  DRETVIKELKKSLKIKGEELSEANVRLS---LLEKKLDSAAKDADERIEKVQTRLEETQA 983

Query: 78   AERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQRE 137
              R++E+ +E                    E ++ALQA + +L+ E+ +     +S  + 
Sbjct: 984  LLRKKEKEFE--------------------ETMDALQADIDQLEAEKAELKQRLNSQSKR 1023

Query: 138  ISQSL---------------------------VEKDSLRRQVFELTDQVCELRTQLRQLQ 170
              + L                           V    L +    L  Q+  +R  + QLQ
Sbjct: 1024 TIEGLRGPPPSGIATLVSGIAGGAIPGQAPGSVPGPGLVKDSPLLLQQISAMRLHISQLQ 1083

Query: 171  AEPPGVLKQEARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSR-E 229
             E   +LK               + ++    P  +     +    SQLL  L+  S+   
Sbjct: 1084 HE-NSILKGAQMKASLASLPPLHVAKLSHEGPGSELPAGALYRKTSQLLETLNQLSTHTH 1142

Query: 230  LVDSFRSSSPAPPSQQSLYKRVAE 253
            +VD  R+S  A      L ++VA+
Sbjct: 1143 VVDITRTSPAAKSPSAQLMEQVAQ 1166



 Score = 30.0 bits (66), Expect = 4.3
 Identities = 25/118 (21%), Positives = 55/118 (46%), Gaps = 3/118 (2%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
           EL+EQ       +E  +   +R     EK+R L  ++ + + + +  DE + + +E    
Sbjct: 405 ELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELE 464

Query: 68  IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125
           +    + A A  R+ ++  E  ++T+  +Q++    + YR+    LQ    EL  +++
Sbjct: 465 LREQLDMAGARVREAQKRVEAAQETVADYQQT---IKKYRQLTAHLQDVNRELTNQQE 519


>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
          Length = 1144

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 46/220 (20%), Positives = 92/220 (41%), Gaps = 16/220 (7%)

Query: 10  QEQSLRTASDQESGDEELNRLK--EENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
           +E+ LR          E  RLK  E+  KL+ L     + + +++   + +  + +L  R
Sbjct: 82  EEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRR 141

Query: 68  IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127
           +   R+ A  A   +E+Y EE   T    + + +  ++  E+  +LQ +V E  KER   
Sbjct: 142 LKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV-EALKER--- 197

Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPC 187
                     + +   + + L+ ++ E          QL+QL+ +   +     R R+  
Sbjct: 198 ----------VDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLS 247

Query: 188 PREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSS 227
             EKQ  V++  +  + + +  +V     +L  +LS   S
Sbjct: 248 SSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAES 287



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 57/254 (22%), Positives = 103/254 (40%), Gaps = 28/254 (11%)

Query: 19   DQESGDEELNR-LKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVA 77
            D+E+  +EL + LK + E+L      L+   +LE+ LD A     E +E++ +  E   A
Sbjct: 813  DRETVIKELKKSLKIKGEELSEANVRLS---LLEKKLDSAAKDADERIEKVQTRLEETQA 869

Query: 78   AERQREQYWEEKEQTL------LQFQKSKMACQLYREKVNALQ-----------AQVCEL 120
              R++E+ +EE    L      L+ +K+++  +L  +    ++             V  +
Sbjct: 870  LLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRGPPPSGIATLVSGI 929

Query: 121  QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 180
              E  Q  +    A   +    + KDS       L  Q+  +R  + QLQ E   +LK  
Sbjct: 930  AGEEQQRGAIPGQAPGSVPGPGLVKDSPL-----LLQQISAMRLHISQLQHE-NSILKGA 983

Query: 181  ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSR-ELVDSFRSSSP 239
                         + ++    P  +     +    SQLL  L+  S+   +VD  R+S  
Sbjct: 984  QMKASLASLPPLHVAKLSHEGPGSELPAGALYRKTSQLLETLNQLSTHTHVVDITRTSPA 1043

Query: 240  APPSQQSLYKRVAE 253
            A      L ++VA+
Sbjct: 1044 AKSPSAQLMEQVAQ 1057



 Score = 30.0 bits (66), Expect = 4.3
 Identities = 25/118 (21%), Positives = 55/118 (46%), Gaps = 3/118 (2%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
           EL+EQ       +E  +   +R     EK+R L  ++ + + + +  DE + + +E    
Sbjct: 291 ELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELE 350

Query: 68  IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125
           +    + A A  R+ ++  E  ++T+  +Q++    + YR+    LQ    EL  +++
Sbjct: 351 LREQLDMAGARVREAQKRVEAAQETVADYQQT---IKKYRQLTAHLQDVNRELTNQQE 405


>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
          Length = 1278

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 46/220 (20%), Positives = 92/220 (41%), Gaps = 16/220 (7%)

Query: 10  QEQSLRTASDQESGDEELNRLK--EENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
           +E+ LR          E  RLK  E+  KL+ L     + + +++   + +  + +L  R
Sbjct: 216 EEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRR 275

Query: 68  IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQA 127
           +   R+ A  A   +E+Y EE   T    + + +  ++  E+  +LQ +V E  KER   
Sbjct: 276 LKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV-EALKER--- 331

Query: 128 YSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPC 187
                     + +   + + L+ ++ E          QL+QL+ +   +     R R+  
Sbjct: 332 ----------VDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLS 381

Query: 188 PREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSS 227
             EKQ  V++  +  + + +  +V     +L  +LS   S
Sbjct: 382 SSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAES 421



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 57/254 (22%), Positives = 103/254 (40%), Gaps = 28/254 (11%)

Query: 19   DQESGDEELNR-LKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVA 77
            D+E+  +EL + LK + E+L      L+   +LE+ LD A     E +E++ +  E   A
Sbjct: 947  DRETVIKELKKSLKIKGEELSEANVRLS---LLEKKLDSAAKDADERIEKVQTRLEETQA 1003

Query: 78   AERQREQYWEEKEQTL------LQFQKSKMACQLYREKVNALQ-----------AQVCEL 120
              R++E+ +EE    L      L+ +K+++  +L  +    ++             V  +
Sbjct: 1004 LLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRGPPPSGIATLVSGI 1063

Query: 121  QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQE 180
              E  Q  +    A   +    + KDS       L  Q+  +R  + QLQ E   +LK  
Sbjct: 1064 AGEEQQRGAIPGQAPGSVPGPGLVKDSPL-----LLQQISAMRLHISQLQHE-NSILKGA 1117

Query: 181  ARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSR-ELVDSFRSSSP 239
                         + ++    P  +     +    SQLL  L+  S+   +VD  R+S  
Sbjct: 1118 QMKASLASLPPLHVAKLSHEGPGSELPAGALYRKTSQLLETLNQLSTHTHVVDITRTSPA 1177

Query: 240  APPSQQSLYKRVAE 253
            A      L ++VA+
Sbjct: 1178 AKSPSAQLMEQVAQ 1191



 Score = 30.0 bits (66), Expect = 4.3
 Identities = 25/118 (21%), Positives = 55/118 (46%), Gaps = 3/118 (2%)

Query: 8   ELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVER 67
           EL+EQ       +E  +   +R     EK+R L  ++ + + + +  DE + + +E    
Sbjct: 425 ELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELE 484

Query: 68  IHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERD 125
           +    + A A  R+ ++  E  ++T+  +Q++    + YR+    LQ    EL  +++
Sbjct: 485 LREQLDMAGARVREAQKRVEAAQETVADYQQT---IKKYRQLTAHLQDVNRELTNQQE 539


>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
          Length = 1476

 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 47/175 (26%), Positives = 82/175 (46%), Gaps = 20/175 (11%)

Query: 10   QEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIH 69
            +E+ ++    Q   +EEL RL+ E+++ + L   LAE   L +   E +G R EL  R+ 
Sbjct: 1141 RERLMQDGHRQRGLEEELRRLQSEHDRAQML---LAE---LSRERGELQGERGELRGRLA 1194

Query: 70   SLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLY-------REKVNALQAQVCELQK 122
             L       E Q +Q  E  +Q  L   +    C+L         E+   L A+V  L +
Sbjct: 1195 RLELERAQLEMQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSR 1254

Query: 123  ER----DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEP 173
            E     +++  +RD   RE  + L + ++LRR+  +L +++ +   Q R L+  P
Sbjct: 1255 ENRELLERSLESRDHLHREQREYLDQLNALRREKQKLVEKIMD---QYRVLEPVP 1306



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 44/172 (25%), Positives = 81/172 (47%), Gaps = 13/172 (7%)

Query: 8   ELQEQS---LRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQEL 64
           EL+E++   L + ++ +  + E+ RL++E + L              ++L E  G    L
Sbjct: 273 ELEEKAELLLDSQAEVQGLEAEIRRLRQEAQALSGQAKRAELYREEAEALRERAGRLPRL 332

Query: 65  VERIHSLRERAVAAERQREQYWEEKEQT-LLQFQKSKMACQLYREKVNALQAQVCELQKE 123
            E +   RER  AAE  + Q  EE+  + +L+  K+     L  E++ A + +   L + 
Sbjct: 333 QEELRRCRERLQAAEAYKSQLEEERVLSGVLEASKA-----LLEEQLEAARERCARLHET 387

Query: 124 RDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPG 175
           + +    R      + ++  E DSLR QV +L ++  EL  +L++    PPG
Sbjct: 388 QRENLLLRT----RLGEAHAELDSLRHQVDQLAEENVELELELQRSLEPPPG 435



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 44/205 (21%), Positives = 84/205 (40%), Gaps = 18/205 (8%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKL-RSLTFSLAEKDILEQSLDEARGSRQEL 64
           E +  EQ+ R     E+  +EL    +E E L  +L  +  E+   E+     R   +  
Sbjct: 784 EAQAWEQA-RLREAVEAAGQELESASQEREALVEALAAAGRERRQWEREGSRLRAQSEAA 842

Query: 65  VERIHSL----RERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCEL 120
            ER+  L    R+    AER+R     EKE    + +K+ +  +    ++  LQ ++ + 
Sbjct: 843 EERMQVLESEGRQHLEEAERERR----EKEALQAELEKAVVRGKELGARLEHLQRELEQA 898

Query: 121 QKERDQAYSARDS--------AQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAE 172
             ER +    ++S         QR  ++      S    + EL  +  +L  +L QL+  
Sbjct: 899 ALERQEFLREKESQHQRYQGLEQRLEAELQAAATSKEEALMELKTRALQLEEELFQLRQG 958

Query: 173 PPGVLKQEARTREPCPREKQRLVRM 197
           P G+  ++    +    +  RL+ +
Sbjct: 959 PAGLGPKKRAEPQLVETQNVRLIEV 983



 Score = 32.3 bits (72), Expect = 0.86
 Identities = 48/198 (24%), Positives = 83/198 (41%), Gaps = 11/198 (5%)

Query: 6    ELELQEQSLRTASDQESGDEELN----RLKEENEKLRSLTFSLAEKDILEQSLDEARGSR 61
            E  L+ +    A+ +E    EL     +L+EE  +LR     L  K   E  L E +  R
Sbjct: 920  EQRLEAELQAAATSKEEALMELKTRALQLEEELFQLRQGPAGLGPKKRAEPQLVETQNVR 979

Query: 62   QELVERIHSLRERAVAAERQREQYWEEKEQTLL-QFQKSKMACQLYREKVNALQAQVCEL 120
               VER +++     AA + + Q+ E +  +L  + Q+  +  Q  +E  + LQA+   L
Sbjct: 980  LIEVERSNAMLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSVL 1039

Query: 121  QKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGV---- 176
            + +  + +   +  + E+  +   ++  R Q   L      L    R+ +AE  G+    
Sbjct: 1040 EIQGQELHRKLEVLEEEVRAARQSQEETRGQQQALLRDHKALAQLQRRQEAELEGLLVRH 1099

Query: 177  --LKQEARTREPCPREKQ 192
              LK   R  E   RE Q
Sbjct: 1100 RDLKANMRALELAHRELQ 1117



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 54/241 (22%), Positives = 82/241 (34%), Gaps = 38/241 (15%)

Query: 75  AVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSA 134
           A A  R+  Q  EEK + LL  Q      +    ++   +AQ    Q +R + Y     A
Sbjct: 263 AKAQLRRLRQELEEKAELLLDSQAEVQGLEAEIRRLRQ-EAQALSGQAKRAELYREEAEA 321

Query: 135 QREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRL 194
            RE +  L       R+  E        ++QL + +     +   +A   E     ++R 
Sbjct: 322 LRERAGRLPRLQEELRRCRERLQAAEAYKSQLEEERVLSGVLEASKALLEEQLEAARERC 381

Query: 195 VRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPAPPSQQSLYKRVAED 254
            R+H             +  E+ LL      +  EL DS R              ++AE+
Sbjct: 382 ARLHE------------TQRENLLLRTRLGEAHAEL-DSLRHQ----------VDQLAEE 418

Query: 255 FGEEPWSFSSCLEIPEGDPGALPGAKAGDPHLDYELLDTADLPQLESSLQPVSPGRLDVS 314
             E        LE P G PG  P A A               P L+  ++    GRL   
Sbjct: 419 NVELELELQRSLEPPPGSPGEAPLAGAA--------------PSLQDEVREAEAGRLRTL 464

Query: 315 E 315
           E
Sbjct: 465 E 465


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 46/192 (23%), Positives = 92/192 (47%), Gaps = 12/192 (6%)

Query: 6    ELELQEQSLRTASDQESGDEE----LNRLKEENEKLRS-LTFSLAEKDILEQSLDEAR-- 58
            E +L E  +   S Q + +EE    L +++ + E + S L   L +++   Q L++A+  
Sbjct: 1000 EKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRK 1059

Query: 59   --GSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQ 116
              G   +L ++I  L+ +    + Q  +  EE +  L +     +      + V  LQAQ
Sbjct: 1060 LDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQ 1119

Query: 117  VCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVC---ELRTQLRQLQAEP 173
            + ELQ++ +   ++R+ A+++      E ++L+ ++ +  D      ELRT+  Q  AE 
Sbjct: 1120 IAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAEL 1179

Query: 174  PGVLKQEARTRE 185
               L++E +  E
Sbjct: 1180 KKALEEETKNHE 1191



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 46/194 (23%), Positives = 89/194 (45%), Gaps = 26/194 (13%)

Query: 8    ELQEQSLRTASDQESGDEELNRLKE--ENEKLRSLTFSLAEKDI------LEQSLDEARG 59
            E +E   R A+ ++  +E L+ L+   E E+ R+      +K +      LE+ LDE  G
Sbjct: 905  EAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEG 964

Query: 60   SRQEL-------VERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKV-- 110
            +RQ+L         +I  + E  +  E Q  ++ +EK+  L++ + ++ + QL  E+   
Sbjct: 965  ARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKK--LMEDRIAECSSQLAEEEEKA 1022

Query: 111  -------NALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELR 163
                   N  +  + +L++   +    R   ++   +   E   L+ Q+ EL  Q+ EL+
Sbjct: 1023 KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELK 1082

Query: 164  TQLRQLQAEPPGVL 177
             QL + + E  G L
Sbjct: 1083 LQLAKKEEELQGAL 1096



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 50/219 (22%), Positives = 95/219 (43%), Gaps = 40/219 (18%)

Query: 12   QSLRTASDQESGDEELNRLKEENEKL--------RSLTFSLAEKDILEQSLDEARGSRQE 63
            Q  R   + ++ DEEL ++KE+  K+        R     L EK+IL + L     +  E
Sbjct: 846  QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQ----AETE 901

Query: 64   LVERIHSLRERAVAAERQREQYW---------EEKEQTLLQFQKSKMACQL--YREKVNA 112
            L      +R R  A +++ E+           EE+   +LQ +K KM   +    E+++ 
Sbjct: 902  LFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDE 961

Query: 113  LQAQVCELQKERDQAYSARDSAQREI-------SQSLVEKDSLRRQVFELTDQVCE---- 161
             +    +LQ E+  A +     + EI       S+ + EK  +  ++ E + Q+ E    
Sbjct: 962  EEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEK 1021

Query: 162  ------LRTQLRQLQAEPPGVLKQEARTREPCPREKQRL 194
                  +R +   + ++    LK+E +TR+   + K++L
Sbjct: 1022 AKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKL 1060



 Score = 38.1 bits (87), Expect = 0.016
 Identities = 43/149 (28%), Positives = 68/149 (45%), Gaps = 11/149 (7%)

Query: 6    ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELV 65
            +LE Q + L+ A  QE      ++ K     L +    L E+  LEQ   E R +  +LV
Sbjct: 1789 QLERQNKELK-AKLQELEGAVKSKFKATISALEAKIGQLEEQ--LEQEAKE-RAAANKLV 1844

Query: 66   ERIHS-LRERAVAAERQR---EQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQ 121
             R    L+E  +  E +R   +QY E+ E+   + ++ K   +   E+     A   +LQ
Sbjct: 1845 RRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQ 1904

Query: 122  KERDQAYSARDSAQREISQSLVEKDSLRR 150
            +E D A  A +   RE+S     K+ LRR
Sbjct: 1905 RELDDATEANEGLSREVS---TLKNRLRR 1930



 Score = 37.7 bits (86), Expect = 0.021
 Identities = 44/182 (24%), Positives = 80/182 (43%), Gaps = 25/182 (13%)

Query: 7    LELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVE 66
            LE Q + +RT    E  ++EL     E+ KLR      A K   E+ L + R  + E  +
Sbjct: 1537 LEQQVEEMRT--QLEELEDELQAT--EDAKLRLEVNMQAMKAQFERDL-QTRDEQNEEKK 1591

Query: 67   RIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYR----------------EKV 110
            R+   + R + AE + E+    K++ L    K KM   L                  +++
Sbjct: 1592 RLLIKQVRELEAELEDER----KQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQL 1647

Query: 111  NALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQ 170
              LQAQ+ + Q+E ++A ++RD    +  +S  +  SL  ++ +L +++       R  +
Sbjct: 1648 RKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAE 1707

Query: 171  AE 172
             E
Sbjct: 1708 QE 1709



 Score = 37.4 bits (85), Expect = 0.027
 Identities = 68/278 (24%), Positives = 114/278 (41%), Gaps = 60/278 (21%)

Query: 11   EQSLRTASDQESGD--EELNRLKEENEKLRSLTFSLAE-KDILEQSLDEARGSRQELVE- 66
            E++ R  ++++  D  EEL  LK E E     T +  E +   EQ + E + + +E  + 
Sbjct: 1130 EKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKN 1189

Query: 67   ---RIHSLRER-AVAAERQREQYWE--------EKEQTLLQFQKSKMACQL--------- 105
               +I  +R+R A A E   EQ  +        EK +  L+    ++AC++         
Sbjct: 1190 HEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAE 1249

Query: 106  ---YREKVNA----LQAQVCE--------------LQKERDQAYSARDSAQREISQSLVE 144
                R+K++A    L A+V E              LQ E D   +  + A+++  +   +
Sbjct: 1250 SEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKD 1309

Query: 145  KDSLRRQ-------VFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPR-EKQRLVR 196
              SL  Q       + E T Q   L +++RQL+ E   + +Q+    E     EKQ L  
Sbjct: 1310 AASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLAL 1369

Query: 197  MHAIC---PRDDSDCSLVSSTE---SQLLSDLSATSSR 228
               +     + D D   + S E    +LL D  A S R
Sbjct: 1370 QSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQR 1407



 Score = 37.4 bits (85), Expect = 0.027
 Identities = 31/151 (20%), Positives = 70/151 (46%), Gaps = 9/151 (5%)

Query: 18   SDQESGDEELNRLKEENEKLRSLTFSL--AEKDILEQSLDEARGSRQELVERIHSLRERA 75
            S  +  D    +L+ +N++L++    L  A K   + ++        +L E++    +  
Sbjct: 1778 SAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKER 1837

Query: 76   VAAERQREQYWEEKEQTLLQFQKSKMACQLYRE---KVNA----LQAQVCELQKERDQAY 128
             AA +   +  ++ ++  +Q +  +     Y+E   K NA    L+ Q+ E ++E  +A 
Sbjct: 1838 AAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRAN 1897

Query: 129  SARDSAQREISQSLVEKDSLRRQVFELTDQV 159
            ++R   QRE+  +    + L R+V  L +++
Sbjct: 1898 ASRRKLQRELDDATEANEGLSREVSTLKNRL 1928



 Score = 33.9 bits (76), Expect = 0.30
 Identities = 46/199 (23%), Positives = 79/199 (39%), Gaps = 32/199 (16%)

Query: 6    ELELQEQSLRTASDQESGDEELNRLKEENEKL---RSLTFSLAEKDILEQS-------LD 55
            +L  +E+S+     +E    E    ++E + L   R+L  +L  K+  E+        ++
Sbjct: 1455 QLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADME 1514

Query: 56   EARGSRQELVERIHSLRERAVAAERQREQ---YWEEKEQTL---------LQFQKSKMAC 103
            +   S+ ++ + +H L +   A E+Q E+     EE E  L         L+     M  
Sbjct: 1515 DLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKA 1574

Query: 104  QLYR----------EKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVF 153
            Q  R          EK   L  QV EL+ E +     R  A     +  ++   L  Q+ 
Sbjct: 1575 QFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1634

Query: 154  ELTDQVCELRTQLRQLQAE 172
                   E+  QLR+LQA+
Sbjct: 1635 AANKARDEVIKQLRKLQAQ 1653



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 41/193 (21%), Positives = 77/193 (39%), Gaps = 20/193 (10%)

Query: 6    ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLA----EKDILEQSLDEARGSR 61
            + ++++        + S DE   + KE  +KL+SL   +     E    E++   A   R
Sbjct: 1651 QAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQER 1710

Query: 62   QELVERIHSL----------RERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVN 111
             EL + I +           + R  A   Q E+  EE++  +           L  + +N
Sbjct: 1711 DELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLN 1770

Query: 112  ALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQA 171
            A  A      ++ D A    +   +E+   L E +   +  F+ T  +  L  ++ QL+ 
Sbjct: 1771 AELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKAT--ISALEAKIGQLEE 1828

Query: 172  EPPGVLKQEARTR 184
            +    L+QEA+ R
Sbjct: 1829 Q----LEQEAKER 1837



 Score = 32.7 bits (73), Expect = 0.66
 Identities = 35/152 (23%), Positives = 71/152 (46%), Gaps = 7/152 (4%)

Query: 25   EELNRLKEENEKLRSLTFSLAEKDIL----EQSLDEARGSRQELVERIHSLRERAVAAER 80
            E+ ++L+ E + + +L     +K I       SL+      QEL++     R++   + R
Sbjct: 1280 EKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQE--ETRQKLNLSSR 1337

Query: 81   QREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQ 140
             R Q  EEK     Q ++ + A +   ++V ALQ+Q+ + +K+ D      +S +    +
Sbjct: 1338 IR-QLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKK 1396

Query: 141  SLVEKDSLRRQVFELTDQVCELRTQLRQLQAE 172
             L + ++L +++ E      +L     +LQ E
Sbjct: 1397 LLKDAEALSQRLEEKALAYDKLEKTKNRLQQE 1428


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 46/216 (21%), Positives = 106/216 (49%), Gaps = 8/216 (3%)

Query: 6   ELELQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSL-AEKDILEQSLDEARGSRQEL 64
           E +L+E+ +  +S      E    L E+NEK+RSL  ++  E + +  + ++A+    E 
Sbjct: 703 EKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQ 762

Query: 65  VERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKER 124
            + +    ER  A   +++Q ++E+E+T+   Q+  +  Q + E ++ L   + E + E 
Sbjct: 763 HKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRL---LTESKGEM 819

Query: 125 DQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVC--ELRTQLRQLQAEPPGVLKQ-EA 181
            +    +D A + + Q+ V +++++ +  +   ++C  EL   L QL+       KQ + 
Sbjct: 820 KKENMKKDEALKAL-QNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKK 878

Query: 182 RTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQ 217
           ++ E    +K+  ++ H++    + +  L  + + Q
Sbjct: 879 KSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQ 914



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 50/253 (19%), Positives = 105/253 (41%), Gaps = 24/253 (9%)

Query: 25   EELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAAERQREQ 84
            +EL +L+   E    LT +L ++++LE  L  A G  +  + ++  LR+    A+   E+
Sbjct: 1042 KELEKLQHSTET--ELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEE 1099

Query: 85   YWEEKEQTLLQFQKSKMACQLYREKV----NALQAQVCELQKERDQAYSARDSAQRE--- 137
             +   +    + ++ KM  +  ++++     AL+ +  EL K+R    +  D   RE   
Sbjct: 1100 KYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWEL-KQRAAQVTHLDMTIREHRG 1158

Query: 138  ------------ISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185
                        + +S +E     +Q+  L D++   + QLR+ +       ++ ++ ++
Sbjct: 1159 EMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKK 1218

Query: 186  PCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPAPPSQQ 245
               R +QR+  M ++    +   +        L  +L  T  RE V +  +       QQ
Sbjct: 1219 EIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLT--REQVQNSHTELAEARHQQ 1276

Query: 246  SLYKRVAEDFGEE 258
               +R  E    E
Sbjct: 1277 VQAQREIERLSSE 1289



 Score = 36.6 bits (83), Expect = 0.046
 Identities = 46/228 (20%), Positives = 96/228 (42%), Gaps = 22/228 (9%)

Query: 28   NRLKEENEKLRSLTFSLAE-KDILEQSLDEARGSRQELVERIHSLRERAVAAERQ----R 82
            N++ EE  K+R L  +L   K+ L   L++  G++++  +++    E     +++     
Sbjct: 835  NQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKN 894

Query: 83   EQYWEEKEQT-LLQFQKSKMACQLYREKVN---------ALQAQVC----ELQKERDQAY 128
                E  EQ  +LQ    +    L +E +           L+ QV     ELQK+R+ + 
Sbjct: 895  HSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSA 954

Query: 129  SARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCP 188
                  + +   +  E D  R++V ELT    +++ ++ Q + E   + K+    +    
Sbjct: 955  EKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGE 1014

Query: 189  REKQRLVRMHAICPRDDSDCSLVSSTES-QLLSDLSATSSRELVDSFR 235
             +   L ++  I   D +   L   T + + L  L  ++  EL ++ +
Sbjct: 1015 NKAMHLSQLDMIL--DQTKTELEKKTNAVKELEKLQHSTETELTEALQ 1060



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 39/177 (22%), Positives = 76/177 (42%), Gaps = 9/177 (5%)

Query: 9   LQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERI 68
           L+EQ +   ++  + D+ L   +E   KL      + EK   EQSL E++    +L   +
Sbjct: 289 LEEQIINLEAEVSAQDKVL---REAENKLEQSQKMVIEK---EQSLQESKEECIKLKVDL 342

Query: 69  HSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAY 128
               ++   AERQR +     E+    FQ+ K   +   EK+  +QA+   L++      
Sbjct: 343 LEQTKQGKRAERQRNEALYNAEELSKAFQQYK---KKVAEKLEKVQAEEEILERNLTNCE 399

Query: 129 SARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTRE 185
                 Q        E + L+ ++ +L ++    + +LR +  +   V+ Q   +R+
Sbjct: 400 KENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQ 456


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 43/186 (23%), Positives = 89/186 (47%), Gaps = 17/186 (9%)

Query: 9   LQEQSLRTASDQESGDEELNRLKEENEKLRSLTFSLAEKDILEQSLDEARGSRQELVERI 68
           L  +  R A +Q   +E+  RL+ E +K       + E+ +  ++  EAR  R+    R 
Sbjct: 602 LLAEKRRQAREQREREEQERRLQAERDK------RMREEQLAREA--EARAEREAEARRR 653

Query: 69  HS--LRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQ 126
                RE+A A + ++E+  ++KE+   + ++     +L REK    Q Q  + +++R +
Sbjct: 654 EEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLE 713

Query: 127 AYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREP 186
               R + + E+S++  ++DS        + +       ++ ++A  PG+ K+  +  EP
Sbjct: 714 EIMKR-TRKSEVSETKQKQDSKEANANGSSPE------PVKAVEARSPGLQKEAVQKEEP 766

Query: 187 CPREKQ 192
            P+E Q
Sbjct: 767 IPQEPQ 772



 Score = 30.0 bits (66), Expect = 4.3
 Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 10/110 (9%)

Query: 87  EEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKD 146
           + +E T L  +K + A +  RE+    + Q   LQ ERD+       A+   +++  E +
Sbjct: 595 DREEATRLLAEKRRQARE-QRER----EEQERRLQAERDKRMREEQLAREAEARAEREAE 649

Query: 147 SLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLVR 196
           + RR+  E  ++    + +  +LQ +     K+EA  R     E+QRL R
Sbjct: 650 ARRREEQEAREKAQAEQEEQERLQKQ-----KEEAEARSREEAERQRLER 694


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.128    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,786,595
Number of Sequences: 37866
Number of extensions: 797405
Number of successful extensions: 6059
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 176
Number of HSP's successfully gapped in prelim test: 612
Number of HSP's that attempted gapping in prelim test: 3598
Number of HSP's gapped (non-prelim): 2219
length of query: 434
length of database: 18,247,518
effective HSP length: 105
effective length of query: 329
effective length of database: 14,271,588
effective search space: 4695352452
effective search space used: 4695352452
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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