Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 16445033

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16445033 ACRC protein [Homo sapiens]
         (691 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16445033 ACRC protein [Homo sapiens]                              1419   0.0  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]   169   6e-42
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo...   100   3e-21
gi|11545835 TSPY-like 2 [Homo sapiens]                                 86   9e-17
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       85   3e-16
gi|55741677 SET domain containing 1A [Homo sapiens]                    80   5e-15
gi|217330641 IWS1 homolog [Homo sapiens]                               80   5e-15
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]                78   2e-14
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]                 78   2e-14
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    74   3e-13
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre...    74   3e-13
gi|55956788 nucleolin [Homo sapiens]                                   74   5e-13
gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]            74   6e-13
gi|87299628 biorientation of chromosomes in cell division 1-like...    73   8e-13
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    72   2e-12
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    71   3e-12
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    71   4e-12
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    71   4e-12
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    71   4e-12
gi|40217843 cartilage oligomeric matrix protein precursor [Homo ...    70   7e-12
gi|27894378 chloride intracellular channel 6 [Homo sapiens]            70   9e-12
gi|115529449 upstream binding transcription factor, RNA polymera...    69   1e-11
gi|115529451 upstream binding transcription factor, RNA polymera...    69   1e-11
gi|7657671 upstream binding transcription factor, RNA polymerase...    69   1e-11
gi|48255931 hepatoma-derived growth factor-related protein 2 iso...    69   1e-11
gi|14249158 hepatoma-derived growth factor-related protein 2 iso...    69   1e-11
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     68   3e-11
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         68   3e-11
gi|42518068 trans-golgi network protein 2 [Homo sapiens]               68   3e-11
gi|210032580 SET domain containing 1B [Homo sapiens]                   67   6e-11

>gi|16445033 ACRC protein [Homo sapiens]
          Length = 691

 Score = 1419 bits (3673), Expect = 0.0
 Identities = 691/691 (100%), Positives = 691/691 (100%)

Query: 1   MDGCKKELPRLQEPEEDEDCYILNVQSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTS 60
           MDGCKKELPRLQEPEEDEDCYILNVQSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTS
Sbjct: 1   MDGCKKELPRLQEPEEDEDCYILNVQSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTS 60

Query: 61  GSSVARRAPKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPP 120
           GSSVARRAPKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPP
Sbjct: 61  GSSVARRAPKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPP 120

Query: 121 IVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPD 180
           IVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPD
Sbjct: 121 IVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPD 180

Query: 181 DNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSD 240
           DNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSD
Sbjct: 181 DNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSD 240

Query: 241 DSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSD 300
           DSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSD
Sbjct: 241 DSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSD 300

Query: 301 DSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAA 360
           DSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAA
Sbjct: 301 DSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAA 360

Query: 361 VSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTI 420
           VSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTI
Sbjct: 361 VSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTI 420

Query: 421 VEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRKAKTKNVSVTPGHKKRGPSKKKPGA 480
           VEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRKAKTKNVSVTPGHKKRGPSKKKPGA
Sbjct: 421 VEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRKAKTKNVSVTPGHKKRGPSKKKPGA 480

Query: 481 AKVEKRKTRTPKCKVPGCFLQDLEKSKKYSGKNLKRNKDELVQRIYDLFNRSVCDKKLPE 540
           AKVEKRKTRTPKCKVPGCFLQDLEKSKKYSGKNLKRNKDELVQRIYDLFNRSVCDKKLPE
Sbjct: 481 AKVEKRKTRTPKCKVPGCFLQDLEKSKKYSGKNLKRNKDELVQRIYDLFNRSVCDKKLPE 540

Query: 541 KLRIGWNNKMVKTAGLCSTGEMWYPKWRRFAKIQIGLKVCDSADRIRDTLIHEMCHAASW 600
           KLRIGWNNKMVKTAGLCSTGEMWYPKWRRFAKIQIGLKVCDSADRIRDTLIHEMCHAASW
Sbjct: 541 KLRIGWNNKMVKTAGLCSTGEMWYPKWRRFAKIQIGLKVCDSADRIRDTLIHEMCHAASW 600

Query: 601 LIDGIHDSHGDAWKYYARKSNRIHPELPRVTRCHNYKINYKVHYECTGCKTRIGCYTKSL 660
           LIDGIHDSHGDAWKYYARKSNRIHPELPRVTRCHNYKINYKVHYECTGCKTRIGCYTKSL
Sbjct: 601 LIDGIHDSHGDAWKYYARKSNRIHPELPRVTRCHNYKINYKVHYECTGCKTRIGCYTKSL 660

Query: 661 DTSRFICAKCKGSLVMVPLTQKDGTRIVPHV 691
           DTSRFICAKCKGSLVMVPLTQKDGTRIVPHV
Sbjct: 661 DTSRFICAKCKGSLVMVPLTQKDGTRIVPHV 691


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score =  169 bits (429), Expect = 6e-42
 Identities = 141/411 (34%), Positives = 199/411 (48%), Gaps = 36/411 (8%)

Query: 17   DEDCYILNVQSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQASSV 76
            D D    +  S S D+S SS +  +     +   +  S S D+S SS +  +     SS 
Sbjct: 902  DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961

Query: 77   VVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDL 136
                SDS +   +     +   + +   +S +      +        S D +D  N +D 
Sbjct: 962  SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD- 1020

Query: 137  EVPDDNSDDSEAPDDNSDDSEAPD--DNSDDSEAPDD-NSDDSEAPDDNSDDSDVPDDNS 193
                 NS DS    D+SD S++ D  D+SD S++ D  NS DS    D+SD SD  D + 
Sbjct: 1021 ---SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1077

Query: 194  DDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPD-----DSSDDSDVPD--DSSDDSEAPD 246
               S ++SD S   NS DS    D SD SD  D     DSSD S+  D  DSSD S++ D
Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1137

Query: 247  -----DSSDDSEAPD--DSSDDSEAPD--DSSDDSEAPDDS-SDDSEASDDSSDDSEASD 296
                 DSSD SE+ D  DSSD S++ D  DSSD S++ D S S DS  S DSSD S++SD
Sbjct: 1138 SSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1197

Query: 297  --DSSDDSEAPD--DKSDDSDVPEDKSDDSDVPDDN-SDDLEVPVPAEDLCNEGQIASDE 351
              DSSD S++ D  D SD SD   D SD SD  D N S D      + D  N    +SD 
Sbjct: 1198 SSDSSDSSDSSDSSDSSDSSD-SSDSSDSSDSSDSNESSDSSDSSDSSDSSN----SSDS 1252

Query: 352  EELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEE 402
             +  +++ + S  DS+D++  Q    N +   SD +++ E S+    T ++
Sbjct: 1253 SDSSDSSDSTS--DSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301



 Score =  166 bits (419), Expect = 9e-41
 Identities = 145/439 (33%), Positives = 215/439 (48%), Gaps = 51/439 (11%)

Query: 17   DEDCYILNVQSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQASSV 76
            D D    +  S+S D+S SS +  +     S   N  S S D+S SS +  +    +S+ 
Sbjct: 852  DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN- 910

Query: 77   VVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDL 136
                SDS +  ++ +  ++     NS D S        +        S D +D  N +D 
Sbjct: 911  ---SSDSSDSSNSSDSSESS----NSSDNSNSSDSSNSSD-------SSDSSDSSNSSDS 956

Query: 137  EVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPD--DNSDDSEAPD--DNSDDSDVPDD- 191
                D+S+ S++ D NS DS    ++SD S++ D  D+SD S++ +  D+SD SD  D  
Sbjct: 957  SNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1016

Query: 192  NSDDSSDDNSDDSSDDNSDDSDVPD--DKSDDSDVPDDS-SDDSDVPDDSSDDSEAPD-- 246
            NS DSS+ +   +S D+SD SD  D  D SD SD  D S S DS    DSSD S++ D  
Sbjct: 1017 NSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1076

Query: 247  DSSDDSEAPD-----DSSDDSEAPD--DSSDDSEAPD--DSSDDSEASD--DSSDDSEAS 295
            DSSD SE+ D     +SSD S++ D  DSSD S++ D  DSSD S +SD  DSSD S++S
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136

Query: 296  D-----DSSDDSEAPD--DKSDDSDVPE--DKSDDSDVPDD-NSDDLEVPVPAEDLCN-- 343
            D     DSSD SE+ D  D SD SD  +  D SD SD  D  NS D      + D  +  
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196

Query: 344  ---EGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTE 400
               +   +SD  +  +++ +    DSSD +   D  E+     S   ++   S     + 
Sbjct: 1197 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSS 1256

Query: 401  EEPAPVVEQSGKRKSKTKT 419
            +      + + +  S++K+
Sbjct: 1257 DSSDSTSDSNDESDSQSKS 1275



 Score =  159 bits (402), Expect = 8e-39
 Identities = 132/400 (33%), Positives = 187/400 (46%), Gaps = 33/400 (8%)

Query: 24   NVQSSSDDTSGSSVARRAPKRQASCILNVQS-RSGDTSGSSVARRAPKRQASSVVVIDSD 82
            N   SSD ++ S  +  +    +S   +  S  S D+S SS +  +     SS     SD
Sbjct: 790  NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849

Query: 83   SDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPD-- 140
              +   ++    +   + +   +S        +        S D +D  N +D +  D  
Sbjct: 850  GSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSS 909

Query: 141  ---DNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSS 197
               D+SD S + D +   + + + NS DS    D+SD S++ + +   +     NS DSS
Sbjct: 910  NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 969

Query: 198  DDNSDDSSDD-NSDDSDVPDDKSDDSDVPD-----DSSDDSDVPDDS-------SDDSEA 244
            D NS DSSD  NS DS    D SD SD  D     DSSD SD  D S       S DS  
Sbjct: 970  DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029

Query: 245  PDDSSDDSEAPD--DSSDDSEAPDDS-SDDSEAPDDSSDDSEASD--DSSDDSEASD--D 297
              DSSD S++ D  DSSD S++ D S S DS    DSSD S++SD  DSSD SE+SD  D
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD 1089

Query: 298  SSDDSEAPD--DKSDDSDVPEDKSDDSDVPD-DNSDDLEVPVPAEDLCNEGQIASDEEEL 354
            SS+ S++ D  D SD SD   D SD SD  D  NS D      + D  ++   +SD  + 
Sbjct: 1090 SSNSSDSSDSSDSSDSSD-SSDSSDSSDSSDSSNSSDSSDSSDSSD-SSDSSNSSDSSDS 1147

Query: 355  VEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSE 394
             E++ +    DSSD +   D  +  S   SD   + + S+
Sbjct: 1148 SESSDSSDSSDSSDSSDSSDSSD--SSDSSDSSNSSDSSD 1185



 Score =  156 bits (394), Expect = 7e-38
 Identities = 131/412 (31%), Positives = 196/412 (47%), Gaps = 32/412 (7%)

Query: 5    KKELPRLQEPEEDEDCYILNVQSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSV 64
            K +  + +    D D    +  S+S D+S +S +  +     S   +  S S D+S SS 
Sbjct: 623  KSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD 682

Query: 65   ARRAPKRQASSVVVIDSDSDEECHTHEEKKAKLLE-INSDDESPECCHVKPAIQEPPIVI 123
            +  +     SS     S+S +   + +   +   +  NS+    +  +   +        
Sbjct: 683  SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742

Query: 124  SDDDNDDDNGNDLEVPDDNSDDSEAPD-----DNSDDSEAPD--DNSDDSEAPD-DNSDD 175
            S D +D  N +D     D+S+ S++ D     D+SD S + D  D+S+ S++ D  NS D
Sbjct: 743  SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD 802

Query: 176  SEAPDDNSDDSDVPDDNSDDSSD-DNSDDSSD-----DNSDDSDVPDDKSDDSDVPDDSS 229
            S    D+SD SD  D +S +SSD  NS DSSD     D+SD SD  D    DS    DSS
Sbjct: 803  SSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSS 862

Query: 230  DDSDVPDDSSDDSEAPD--DSSDDSEAPD--DSSDDSEAPDDSSDDSEAPDDSSDDSEAS 285
            + SD   DSSD S + D  DSSD +E+ +  DSSD S + D  S DS    DSSD S +S
Sbjct: 863  NSSD-SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS 921

Query: 286  D-----DSSDDSEASD--DSSDDSEAPD-DKSDDSDVPEDKSDDSDVPDDNSDDLEVPVP 337
            D     +SSD+S +SD  +SSD S++ D   S DS    D S+ SD  D NS D      
Sbjct: 922  DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981

Query: 338  AEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEAN 389
            + D  +    +SD  +  +++ + +  DSSD +   D   +     S   +N
Sbjct: 982  SSDSSD----SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029



 Score =  155 bits (392), Expect = 1e-37
 Identities = 108/292 (36%), Positives = 152/292 (52%), Gaps = 31/292 (10%)

Query: 124 SDDDNDDDNGNDLEVPDDNSDDSEAPDDNS----------DDSEAPDDNSDDSEAPDDNS 173
           SD+  D+ NG+D +  +D+  DS +  +NS          DD++  D     S++ D +S
Sbjct: 495 SDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDS 554

Query: 174 DDSEAPDDNSD--DSDVPDDNS---DDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDS 228
            DS    D+SD  DSD  D NS    DSSD +S DSSD +S DS    D SD SD   DS
Sbjct: 555 SDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSD-SSDS 613

Query: 229 SDDSDVPDDSSDDSEAPDDSSDD---SEAPDDSSDDSEAPDDSSDDSEAPD--DSSDDSE 283
           SD SD  D  SD S++  DSSD    S++ D +S DS    DSSD S + +  DSSD S+
Sbjct: 614 SDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSD 673

Query: 284 ASD-DSSDDSEASDDSSDDSEAPD-----DKSDDSDVPEDKSDDSDVPDDNSDDLEVPVP 337
           +SD  SS DS  S DSSD S++ +     D SD SD   D SD SD  + NS D +    
Sbjct: 674 SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSD--SDSSDSSDSSNSNSSDSDSSNS 731

Query: 338 AEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEAN 389
           ++   ++   +SD  +  +++ +    DSSD +   D  ++     S   +N
Sbjct: 732 SDS--SDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781



 Score =  154 bits (390), Expect = 2e-37
 Identities = 114/375 (30%), Positives = 174/375 (46%), Gaps = 12/375 (3%)

Query: 24   NVQSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQASSVVVIDSDS 83
            N  SS  D+S SS +  +     S   +  S S D+S SS +  +     SS     SDS
Sbjct: 720  NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS 779

Query: 84   DEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPD-DN 142
                 +++   +   + +    S +  +   +        SD  N  D+ N  +  D  N
Sbjct: 780  SNSSDSNDSSNSS--DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837

Query: 143  SDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSD 202
            S DS    D+SD S++   N  DS    D+SD S++  ++SD SD  D N   +S D+SD
Sbjct: 838  SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS-SNSSDSSDSSDSNESSNSSDSSD 896

Query: 203  --DSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSD 260
              +SSD +S DS    D SD S+  D S   +   + +S DS    DSSD S++   +S 
Sbjct: 897  SSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS--SNSS 954

Query: 261  DSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSD 320
            DS    DSS+ S++ D +S DS  S +SSD S++SD S     +    S DS    D SD
Sbjct: 955  DSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1014

Query: 321  DSDVPD-DNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENL 379
             S+  D  NS D      + D  ++   +SD  +  +++ + +  DSSD +   D  +  
Sbjct: 1015 SSNSSDSSNSSDSSNSSDSSD-SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD-- 1071

Query: 380  SKPPSDPEANPEVSE 394
            S   SD   + E S+
Sbjct: 1072 SSDSSDSSDSSESSD 1086



 Score =  153 bits (386), Expect = 6e-37
 Identities = 124/377 (32%), Positives = 185/377 (49%), Gaps = 27/377 (7%)

Query: 27   SSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQASSVVVIDSDSDEE 86
            S+S D+S SS +  +     S   +  S S D+S SS +  +     S+     SDS + 
Sbjct: 738  SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797

Query: 87   CHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDS 146
             ++ +   +     +SD    +  +   +        S D +D  N +D     D+SD S
Sbjct: 798  SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN------SSDSSDSSNSSDSSDSSDSSDGS 851

Query: 147  EAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDN-----SDDSDVPDDNSDDSSDD-N 200
            ++   N  DS    D+SD S++  ++SD S++ D N     SD SD  + +  DSSD  N
Sbjct: 852  DSDSSNRSDSSNSSDSSDSSDS-SNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910

Query: 201  SDDSSD-DNSDDSDVPDDKSDDSDVPD--DSSDDSDVPDDS-SDDSEAPDDSSDDSEAPD 256
            S DSSD  NS DS    + SD+S+  D  +SSD SD  D S S DS    DSS+ S++ D
Sbjct: 911  SSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 970

Query: 257  DSSDDSEAPDDSSDDSEAPDDSSDDSEASDDS-SDDSEASDDSSDDSEAPD-DKSDDSDV 314
             +S DS    +SSD S++  DSSD S++SD S S DS  S DSSD S + D   S DS  
Sbjct: 971  SNSSDSSDSSNSSDSSDS-SDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029

Query: 315  PEDKSDDSDVPD--DNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGE 372
              D SD SD  D  D+SD  +    + D  N    +SD  +  +++ +    DSSD +  
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSD----SSDSSNSSD-SSDSSDSSDSSDSSDSSDSSDSSES 1084

Query: 373  QDLGENLSKPPSDPEAN 389
             D  ++ +   S   ++
Sbjct: 1085 SDSSDSSNSSDSSDSSD 1101



 Score =  152 bits (385), Expect = 8e-37
 Identities = 126/404 (31%), Positives = 187/404 (46%), Gaps = 40/404 (9%)

Query: 27  SSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQASSVVVIDSDSDEE 86
           SSSD  S  S +  +    +S      S S D+S SS +  +     SS    DS   E 
Sbjct: 576 SSSDSDSSDSDSSDSSDSDSSD----SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631

Query: 87  CHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISD--DDNDDDNGNDLEVPDDNSD 144
             +  + K+   + NS D S        +        SD  D +D  + +D     D+SD
Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691

Query: 145 DSEAPD--DNSDDSEAPD-DNSDDSEAPDDNSDDSEAPD-----DNSDDSDVPDDNSDDS 196
            S++ +  ++SD S++ D D+SD S++ + NS DS++ +     D+S+ SD  D +   +
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN 751

Query: 197 SDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDS-SDDSDVPDDSSDDSEAPD--DSSDDSE 253
           S D+SD S   NS DS    D SD SD  + S S+DS    DSSD S + D  +SSD S+
Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811

Query: 254 APDDSSDDSEAPDDSSDDSEAPD-----DSSDDSEASDDSSDDSEASDDSSDDSEAPD-- 306
           + D S  DS    DSS+ S++ D     DSSD S++SD S  DS    DSS+ S++ D  
Sbjct: 812 SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSS 871

Query: 307 ------DKSDDSDVPE-----DKSDDSDVPDDNSDDLEVPVPAEDLCN-----EGQIASD 350
                 D SD SD  E     D SD S+  D +S D      + D  N     E   +SD
Sbjct: 872 DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931

Query: 351 EEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSE 394
                +++ +    DSSD +   D   +     S   ++   S+
Sbjct: 932 NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD 975



 Score =  150 bits (380), Expect = 3e-36
 Identities = 112/351 (31%), Positives = 170/351 (48%), Gaps = 14/351 (3%)

Query: 54  SRSGDTSGSSVARRAPKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVK 113
           S S D+S SS +  +    +S     DSDS +   +     +   + +   +S +     
Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSS 617

Query: 114 PAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 173
            +          + +  D+ +  +  D NS DS    D+SD S +   NS DS    D+S
Sbjct: 618 DSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNS--SNSSDSSDSSDSS 675

Query: 174 DDSEAPD--DNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPD--DSS 229
           D S + D  ++SD SD  D ++   S D+SD S  D+SD SD  +  S DSD  +  DSS
Sbjct: 676 DSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSS 735

Query: 230 DDSDVPD--DSSDDSEAPDDS-SDDSEAPDDSSDDSEAPDDSSDDSEAPD--DSSDDSEA 284
           D S+  D  DSSD S + D S S DS    DSSD S++  DSSD S + D  DSS+ S++
Sbjct: 736 DSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS-SDSSDSSNSSDSNDSSNSSDS 794

Query: 285 SDDS-SDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCN 343
           SD S S DS  S DSSD S++ D  S +S    + SD SD   ++SD  +    ++   +
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD-SSNSSDSSDSSDSSDGSDS 853

Query: 344 EGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSE 394
           +    SD     +++ +    +SSD +   D  E+ +   S   +N   S+
Sbjct: 854 DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904



 Score =  148 bits (374), Expect = 1e-35
 Identities = 131/413 (31%), Positives = 198/413 (47%), Gaps = 54/413 (13%)

Query: 27  SSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQASSVVVIDSDSDEE 86
           +SSD+++G+  A            N  S  GD S +S   +     + S    D DSD  
Sbjct: 466 NSSDESNGNDDANSESD-------NNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDST 518

Query: 87  CHTHE-EKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNS-- 143
             T+  +        N D++  +    K    +     S + +D  + +D +  D NS  
Sbjct: 519 SDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSS 578

Query: 144 -------DDSEAPDDNSDDSEAPDDNSDDSEAPD--DNSDDSEAPDDNS------DDSDV 188
                  D S++ D +S DS    D+SD S++ D  D+SD S++  D+S       DSD 
Sbjct: 579 DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS 638

Query: 189 PDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPD-----DSSDDSDVPD--DSSDD 241
             D+SD +S D+SD+S   +S +S    D SD SD  D     DSS+ SD  D  DSS+ 
Sbjct: 639 KSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNS 698

Query: 242 SEAPD-------DSSDDSEAPDDSSDDSEAPD--DSSDDSEAPD--DSSDDSEASD--DS 288
           SE+ D       DSSD S++ + +S DS++ +  DSSD S + D  DSSD S +SD  DS
Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758

Query: 289 SDDSEASD--DSSDDSEAPDDK----SDDSDVPEDKSDDSDVPD-DNSDDLEVPVPAEDL 341
           SD S +SD  DSSD S++ D      S+DS    D SD S+  D  NS D      + D 
Sbjct: 759 SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD- 817

Query: 342 CNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSE 394
            ++   +SD     +++ + +  DSSD +   D  ++ S   SD   + + S+
Sbjct: 818 -SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD 869



 Score =  146 bits (368), Expect = 7e-35
 Identities = 119/382 (31%), Positives = 177/382 (46%), Gaps = 28/382 (7%)

Query: 28  SSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQASSVVVIDSDSDEEC 87
           SSD  S SS +        S   +  S S D+S +S +  +     SS     SDS +  
Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678

Query: 88  HTHEEKKAKLLEINSDDE-SPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDS 146
            + +   +     +SD   S E      +        S D +D  N N  +    NS DS
Sbjct: 679 SSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSD----SSDSSDSSNSNSSDSDSSNSSDS 734

Query: 147 EAPDDNSDDSEAPDD-NSDDSEAPDDNSDDSEAPD--DNSDDSDVPDDNSDDSSDDNSDD 203
               ++SD S++ D  NS DS    D+S+ S++ D  D+SD SD  + +  + S ++SD 
Sbjct: 735 SDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS 794

Query: 204 SSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPD--DSSDD 261
           S   NS DS    D SD SD  D  S +S    +SSD S    DSS+ S++ D  DSSD 
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS----DSSNSSDSSDSSDSSDG 850

Query: 262 SEAPDDSSDDSEAPDDSSDDSEASD-----DSSDDSEASD--DSSDDSEAPDDKSDDSDV 314
           S++   +  DS    DSSD S++S+     DSSD +E+S+  DSSD S + D  S DS  
Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910

Query: 315 PEDKSDDSDVPDDNSDDLEVPVPAEDLCN--EGQIASDEEELVEAAAAVSQHDSSDDAGE 372
             D SD S     NS D      + D  N  +   +SD  +  +++ +    +SSD +  
Sbjct: 911 SSDSSDSS-----NSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNS 965

Query: 373 QDLGENLSKPPSDPEANPEVSE 394
            D  ++ S   SD   + + S+
Sbjct: 966 SDSSDSNSSDSSDSSNSSDSSD 987



 Score =  139 bits (351), Expect = 7e-33
 Identities = 100/285 (35%), Positives = 135/285 (47%), Gaps = 26/285 (9%)

Query: 125 DDDN--DDDNGND--LEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD---DSE 177
           DD N  D+ NGND      D+NS        NSD+S+   + SD   A DD+SD   D+ 
Sbjct: 463 DDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTN 522

Query: 178 APDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDD 237
             D N + ++  DDN    S     DSSD +S DS    D SD SD   DSSD +   D 
Sbjct: 523 NSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSD--SDSSDSNSSSDS 580

Query: 238 SSDDSEAPDDSSDDSEAPDDSSDDSEAPD--DSSDDSEAPDDSSDDSEASDDSSDDSEAS 295
            S DS++ D S  DS    +SSD S++ D  DSSD S++ D  SD S++  DSSD    S
Sbjct: 581 DSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKS 640

Query: 296 DDSSDDSEAPDDKSDDSDV-----PEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASD 350
           D S  +S    D SD SD        D SD SD  D +S        + D  N    +SD
Sbjct: 641 DSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS--------SSDSSNSSD-SSD 691

Query: 351 EEELVEAAAAVSQHDSSD-DAGEQDLGENLSKPPSDPEANPEVSE 394
             +   ++ +    DSSD D+ +     N +   SD   + + S+
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736



 Score =  138 bits (348), Expect = 1e-32
 Identities = 93/279 (33%), Positives = 147/279 (52%), Gaps = 18/279 (6%)

Query: 124 SDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDD---NSDDSEAPD 180
           SD ++D  +  D +      DD  + D+++ + +A  ++ ++S +  D   NSD+S+   
Sbjct: 443 SDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNG 502

Query: 181 DNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSD 240
           + SD     DD+SD +SD N+ DS+ + ++ +D  +DKSD      DSSD      DSSD
Sbjct: 503 NGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGND-DNDKSDSGKGKSDSSD-----SDSSD 556

Query: 241 DSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASD--DS 298
            S +  DSSD S++  DSSD + + D  S DS++ D S  DS  S +SSD S++SD  DS
Sbjct: 557 SSNS-SDSSDSSDS--DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613

Query: 299 SDDSEAPDDKSDDSDVPEDKSDD---SDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELV 355
           SD S++ D KSD S    D SD    SD  D NS D      + D  N    +SD  +  
Sbjct: 614 SDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSN-SSDSSDSS 672

Query: 356 EAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSE 394
           +++ + S  DSS+ +   D  ++ +   S   ++   S+
Sbjct: 673 DSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSD 711



 Score =  114 bits (285), Expect = 3e-25
 Identities = 80/267 (29%), Positives = 126/267 (47%), Gaps = 15/267 (5%)

Query: 128 NDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSD 187
           N +  G   E  +     +   D NSD  ++ D +    +  D NS D     + +DD++
Sbjct: 422 NIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDES---NGNDDAN 478

Query: 188 VPDDNSDDSSDDNS--DDSSDDNSDDSDVPDDKSDDSDVPDDS--SDDSDVPDDSSDDSE 243
              DN+  S  D S   D S DN + SD    + DDSD   D+  SD +   ++ +DD++
Sbjct: 479 SESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDND 538

Query: 244 APDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSE 303
             D     S++ D  S DS    DSSD S++  DSSD + +SD  S DS++SD S  DS 
Sbjct: 539 KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDS--DSSDSNSSSDSDSSDSDSSDSSDSDSS 596

Query: 304 APDDKSDDSDVPE--DKSDDSDVPDDNSDDLEVPVPAEDLCNEGQI----ASDEEELVEA 357
              + SD SD  +  D SD SD  D  SD  +    + D  ++       +SD  +  ++
Sbjct: 597 DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS 656

Query: 358 AAAVSQHDSSDDAGEQDLGENLSKPPS 384
           + + +  +SSD +   D  ++ S   S
Sbjct: 657 SDSSNSSNSSDSSDSSDSSDSSSSSDS 683



 Score =  100 bits (248), Expect = 6e-21
 Identities = 84/281 (29%), Positives = 120/281 (42%), Gaps = 60/281 (21%)

Query: 13   EPEEDEDCYILNVQSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQ 72
            +  E  D    +  S S D+S SS +               S S D+S SS +  +    
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDS---------------SDSSDSSDSSDSSDSSNSS 1124

Query: 73   ASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDN 132
             SS     SDS +  +                                   S D +D   
Sbjct: 1125 DSSDSSDSSDSSDSSN-----------------------------------SSDSSDSSE 1149

Query: 133  GNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDN 192
             +D     D+SD S++ D +     +   NS DS    D+SD S++  D+SD SD  D  
Sbjct: 1150 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS-SDSSDSSDSSD-- 1206

Query: 193  SDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDS 252
            S DSSD +    S D+SD SD     S DS+   DSSD SD   DSS+ S++  DSSD S
Sbjct: 1207 SSDSSDSSDSSDSSDSSDSSD-----SSDSNESSDSSDSSD-SSDSSNSSDS-SDSSDSS 1259

Query: 253  EAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSE 293
            ++  DS+D+S++   S + +    DS  DSE SD +   S+
Sbjct: 1260 DSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSD 1300



 Score = 96.7 bits (239), Expect = 7e-20
 Identities = 70/232 (30%), Positives = 107/232 (46%), Gaps = 6/232 (2%)

Query: 157 EAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPD 216
           E P   S+       ++  S++  D  D  D  DD S    D NS D S+ N D +   D
Sbjct: 424 EGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDF-DDKSMQGDDPNSSDESNGNDDANSESD 482

Query: 217 DKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPD 276
           + S        +SD+S    + SD   A DD SD S +  ++SD +   ++ +DD++  D
Sbjct: 483 NNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSD-STSDTNNSDSNGNGNNGNDDNDKSD 541

Query: 277 DSSDDSEASDDSSDDSEASDDSSD--DSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEV 334
                S++SD  S DS  S DSSD  DS++ D  S  SD     SD SD  D +S D   
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS-SSDSDSSDSDSSDSSDSDSSDSSN 600

Query: 335 PVPAEDLCNEGQIA-SDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSD 385
              + D  +    + S +    ++ ++ S+ DSSD   + D  ++ S   SD
Sbjct: 601 SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSD 652



 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 40/227 (17%)

Query: 200 NSDDSSDDNSD--DSDVPDDKS---DDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEA 254
           +S+  SD NSD  DS   DDKS   DD +  D+S+ + D   +S ++S +  D+S +S+ 
Sbjct: 438 HSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDE 497

Query: 255 PDDSSD--DSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDS 312
             D+ +  DS+  +D   DS +  ++SD +   ++ +DD++ SD     S++ D  S DS
Sbjct: 498 SKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS 557

Query: 313 DVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGE 372
               D SD SD   D+SD                               S   S  D+ +
Sbjct: 558 SNSSDSSDSSD--SDSSD-------------------------------SNSSSDSDSSD 584

Query: 373 QDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKT 419
            D  ++     SD   + + S+    ++   +     S    SK+++
Sbjct: 585 SDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 79/386 (20%), Positives = 142/386 (36%), Gaps = 77/386 (19%)

Query: 80  DSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVP 139
           D   +  C           +INS     +   V P   E   + + D +   NG D +  
Sbjct: 197 DEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDED 256

Query: 140 DDNSDDSEAPDDNSDDSEAPDDNSDDSEAPD----DNSDDSEAPDDNSDDSDVPDDNSDD 195
           + + DD +    N  DS    +NS   E  D    D+ D S   + +S +   P+   D 
Sbjct: 257 EGSGDDEDEEAGNGKDS---SNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDP 313

Query: 196 SSDDNSDDSSDDNSDDSDVPDD----------------------------------KSDD 221
            ++ + D +S    + + +P+D                                  KS D
Sbjct: 314 HNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQD 373

Query: 222 S--DVPDDSSDDSDVPDDSSDDSEAPDDSSD-----------------DSEAPDDSSD-- 260
              ++   SS + ++  +    +E  +D                    + E P   S+  
Sbjct: 374 KGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPG 433

Query: 261 -----DSEAPDDSSD--DSEAPDDSS---DDSEASDDSSDDSEASDDSSDDSEAPDDKSD 310
                 +   D +SD  DS   DD S   DD  +SD+S+ + +A+ +S ++S +  D S 
Sbjct: 434 NKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASY 493

Query: 311 DSDVPEDKSDDSD---VPDDNSDDLEVPVPAED--LCNEGQIASDEEELVEAAAAVSQHD 365
           +SD  +D  + SD     DD+SD       ++     N G   +D+ +  +  +  S  D
Sbjct: 494 NSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSD 553

Query: 366 SSDDAGEQDLGENLSKPPSDPEANPE 391
           SSD +   D  ++     SD  ++ +
Sbjct: 554 SSDSSNSSDSSDSSDSDSSDSNSSSD 579



 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 50/202 (24%), Positives = 94/202 (46%), Gaps = 10/202 (4%)

Query: 222 SDVPDDSSDDSDVPDDS--SDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSS 279
           SD   D  D  D  D S   DD  + D+S+ + +A  +S ++S +  D+S +S+   D+ 
Sbjct: 443 SDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNG 502

Query: 280 DDSEASDDSSDDSEAS-----DDSSDDSEAPDDKSDDSDVPEDKSDDSDV-PDDNSDDLE 333
           + S++     DDS+++      DS+ +    +D +D SD  + KSD SD    D+S+  +
Sbjct: 503 NGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSD 562

Query: 334 VPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVS 393
               ++   ++   +SD +     ++  S  DSSD +   D  +  S   SD   + + S
Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSD--SSDSSDSSDSSDSS 620

Query: 394 ERKLPTEEEPAPVVEQSGKRKS 415
           + K  + +  +   +   K  S
Sbjct: 621 DSKSDSSKSESDSSDSDSKSDS 642



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 34/193 (17%), Positives = 81/193 (41%), Gaps = 9/193 (4%)

Query: 145 DSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDS 204
           D+    + S+ +   D N+ + +  D   ++  A            +NS D+ D+  ++S
Sbjct: 144 DNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENS 203

Query: 205 SDDNSDDSDVPD------DKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDS 258
             +  + S++        + + +++V   + +D+ + +     S    D  +D  + DD 
Sbjct: 204 CRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDE 263

Query: 259 SDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSD---VP 315
            +++    DSS++S+  +      E   DSS    +      D E  +D  ++ D     
Sbjct: 264 DEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTS 323

Query: 316 EDKSDDSDVPDDN 328
           + + + + +P+DN
Sbjct: 324 KSEENSAGIPEDN 336



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 43/193 (22%), Positives = 76/193 (39%), Gaps = 19/193 (9%)

Query: 128 NDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSE-------APDDNSDDSEAPD 180
           N D N  + +V D   ++  A         A  +NS D+E         ++ +     P 
Sbjct: 157 NTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQ 216

Query: 181 DNSD-----DSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVP 235
            NS      +++V     +D+  DNSD S   N  D D  +   DD D      +++   
Sbjct: 217 INSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDED------EEAGNG 270

Query: 236 DDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDS-SDDSEA 294
            DSS++S+  +      E   DSS    +      D E  +D  ++ +    S S+++ A
Sbjct: 271 KDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSA 330

Query: 295 SDDSSDDSEAPDD 307
                + S+  +D
Sbjct: 331 GIPEDNGSQRIED 343



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 80/343 (23%), Positives = 132/343 (38%), Gaps = 46/343 (13%)

Query: 162 NSDDSEAPDDNSDDSEAPDDNSDDSDVPD-----DNSDDSSDDNSDDSSDDNSDDSDVPD 216
           N D  +A     D     ++N   + +       DN+  ++  N++ ++D N+ + DV D
Sbjct: 110 NGDTGKAETYGHDGIHGKEENITANGIQGQVSIIDNAGATNRSNTNGNTDKNTQNGDVGD 169

Query: 217 --DKSDDSDVPDDS-----SDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDS---EAPD 266
                D + V +D      S++S   +D   ++   ++ +     P  +S  +   EA  
Sbjct: 170 AGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEV 229

Query: 267 DSSDDSEAPDDSSDDSEASD--DSSDDSEASDDSSDDSEAPDDKSDDSDVPE----DKSD 320
                 +A  D+SD S + +  D  +D  + DD  +++    D S++S   E     K D
Sbjct: 230 TPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKED 289

Query: 321 DSDVP-DDNSDDLEV--PVPAEDLCNE--GQIASDEEELVEAAAAVSQHDSSDDAGEQDL 375
           D D     NSD  E   P   ED  NE  G   S  EE   +A     + S      Q L
Sbjct: 290 DHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEE--NSAGIPEDNGSQRIEDTQKL 347

Query: 376 GENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRKRQTKTKNIV 435
               SK            E ++  E E   V    GK + K   I  P    +  TK + 
Sbjct: 348 NHRESKR----------VENRITKESETHAV----GKSQDKGIEIKGPSSGNRNITKEVG 393

Query: 436 EPPRKRQTKTKNIVEPLRKRKAKTKNVSVT---PGHKKRGPSK 475
           +    ++ K ++ +  L K   KT+   V    PG K    +K
Sbjct: 394 KGNEGKEDKGQHGM-ILGKGNVKTQGEVVNIEGPGQKSEPGNK 435


>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
           [Homo sapiens]
          Length = 666

 Score =  100 bits (250), Expect = 3e-21
 Identities = 94/360 (26%), Positives = 145/360 (40%), Gaps = 34/360 (9%)

Query: 54  SRSGDTSGSSVARRAPKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVK 113
           S SG  S S     A    AS     +SD DE   + +    +L   +S+DE     H  
Sbjct: 21  SDSGSDSDSDQENAASGSNASGS---ESDQDERGDSGQPSNKELFGDDSEDEGAS--HHS 75

Query: 114 PAIQEPPIVISDDDND-DDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDN 172
                     SD+ ++  DN ++     D+ D+  +  D    SEAP+D+ D+    D  
Sbjct: 76  G---------SDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGG 126

Query: 173 SDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDS 232
           S  SEA       SD      +D SD  SDD    NSDD +    +  D D   +S DD 
Sbjct: 127 SHHSEAEGSEKAHSDDEKWGREDKSDQ-SDDEKIQNSDDEERA--QGSDEDKLQNSDDDE 183

Query: 233 DVPDDSSDDSEAPDDSSDD----SEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDS 288
            +   ++DD E P  S D+    SE    +SDD       +DD +   D  +  + SD+ 
Sbjct: 184 KM--QNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDE- 240

Query: 289 SDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIA 348
            +  + SDD    +   + +  D +  +D   +S    D+ D++        + ++ +  
Sbjct: 241 -EKMQNSDDERPQASDEEHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEAD 299

Query: 349 SDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLP---TEEEPAP 405
           SD E   + +  +     +DD      GE+    P  P     V E  LP    EEEP P
Sbjct: 300 SDTEVPKDNSGTMDLFGGADDISSGSDGEDKPPTPGQP-----VDENGLPQDQQEEEPIP 354



 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 80/274 (29%), Positives = 122/274 (44%), Gaps = 34/274 (12%)

Query: 127 DNDDDNGNDLEVPDDNSDDSEAPDDNSD-DSEAPDDNSDDSEAPDDNSDDSEAPDDNSDD 185
           D +D  G+D +   +  D     D +SD ++ A   N+  SE+  D   DS  P +    
Sbjct: 3   DMEDLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELF 62

Query: 186 SDVPDDN--SDDSSDDNSDDSSDDNSDDSDVPDDKSDD-SDVPDDSSDDSDVPDDSSDDS 242
            D  +D   S  S  DN  + SD+ S+ S+  D + +D SDV  D    S+ P+D  D+ 
Sbjct: 63  GDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDV--DQHSGSEAPNDDEDEG 120

Query: 243 EAPDDSSDDSEAPDD----SSDDSEAPDDSSD--DSEAPDDSSDDSEASDDSSDDSEASD 296
              D  S  SEA       S D+    +D SD  D E   +S D+  A     D  + SD
Sbjct: 121 HRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSD 180

Query: 297 D-----SSDDSEAP-----------DDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAED 340
           D     ++DD E P           +++  +SD     + D+D    NSDD E P     
Sbjct: 181 DDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQP----Q 236

Query: 341 LCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQD 374
           L +E ++ + ++E  +A+    +H  SDD  EQD
Sbjct: 237 LSDEEKMQNSDDERPQASD--EEHRHSDDEEEQD 268



 Score = 92.8 bits (229), Expect = 9e-19
 Identities = 82/301 (27%), Positives = 134/301 (44%), Gaps = 23/301 (7%)

Query: 135 DLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSD 194
           D+E    +  DSEA   +SD S +  D+  ++ A   N+  SE+  D   DS  P +   
Sbjct: 3   DMEDLFGSDADSEAERKDSD-SGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNK-- 59

Query: 195 DSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEA 254
              +   DDS D+ +      D+ S+ SD   ++S+ SD  D+   D     D    SEA
Sbjct: 60  ---ELFGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDV----DQHSGSEA 112

Query: 255 PDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDS---SDDSEASDDSSDDSEAPDDKSDD 311
           P+D  D+    D  S  SEA  + S+ + + D+     D S+ SDD    +   ++++  
Sbjct: 113 PNDDEDEGHRSDGGSHHSEA--EGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQG 170

Query: 312 SDVPEDKSDDSDVPDDNSDDLEVPVPAED----LCNEGQIASDEEELVEAAAAVSQHDSS 367
           SD  + ++ D D    N+DD E P  ++D    L  E +  SD+E  V A+    +  +S
Sbjct: 171 SDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERPV-ASDNDDEKQNS 229

Query: 368 DDAGEQDLGENLSKPPSDPEANPEVS--ERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPR 425
           DD  +  L +      SD E  P+ S  E +   +EE      +S +       ++   R
Sbjct: 230 DDEEQPQLSDEEKMQNSDDE-RPQASDEEHRHSDDEEEQDHKSESARGSDSEDEVLRMKR 288

Query: 426 K 426
           K
Sbjct: 289 K 289



 Score = 80.5 bits (197), Expect = 5e-15
 Identities = 71/272 (26%), Positives = 113/272 (41%), Gaps = 33/272 (12%)

Query: 164 DDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSD 223
           +D    D +S+      D+  DSD   +N+   S+ +  +S  D   DS  P +K    D
Sbjct: 5   EDLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGD 64

Query: 224 VPDDSSDDSDVPDDSSDD-SEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDS 282
              DS D+       SD+ SE  D+ S+ SE  D   +D    D  S  SEAP+D  D+ 
Sbjct: 65  ---DSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSG-SEAPNDDEDEG 120

Query: 283 EASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLC 342
             SD  S  SEA  + S+ + + D+K       EDKSD SD                   
Sbjct: 121 HRSDGGSHHSEA--EGSEKAHSDDEKWGR----EDKSDQSD------------------- 155

Query: 343 NEGQIA-SDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEE 401
            + +I  SD+EE  + +      +S DD   Q+  +   +P    +   ++SE +    +
Sbjct: 156 -DEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDE-ERPQLSDDERQQLSEEEKANSD 213

Query: 402 EPAPVVEQSGKRKSKTKTIVEPPRKRQTKTKN 433
           +  PV   +   K  +    +P    + K +N
Sbjct: 214 DERPVASDNDDEKQNSDDEEQPQLSDEEKMQN 245


>gi|11545835 TSPY-like 2 [Homo sapiens]
          Length = 693

 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 55/212 (25%), Positives = 112/212 (52%), Gaps = 14/212 (6%)

Query: 127 DNDDDNGNDLEVPDDNSDDSEAPD-DNSDDSEAPDDN--SDDSEAPDDNSDDSEAPDDNS 183
           DN+  + N+     +N D +E P+ + +D++E+ DD+  +D++E+ DDN+++ E  + N+
Sbjct: 466 DNEITDINENICDSENPDHNEVPNNETTDNNESADDHETTDNNESADDNNENPEDNNKNT 525

Query: 184 DDSDVPDDNSDDSSDDN--------SDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVP 235
           DD++   +N++++  +N        S  ++ D+SD  +  D+ SDD D   +  D+    
Sbjct: 526 DDNEENPNNNENTYGNNFFKGGFWGSHGNNQDSSDSDNEADEASDDEDNDGNEGDNEGSD 585

Query: 236 DDSSD-DSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEA 294
           DD ++ D+E  DD   D E  +   +D +   D +D  +  +  SD+S   +   +  + 
Sbjct: 586 DDGNEGDNEGSDDDDRDIEYYEKVIEDFD--KDQADYEDVIEIISDESVEEEGIEEGIQQ 643

Query: 295 SDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPD 326
            +D  ++    ++ S+D     + SDDSD+ D
Sbjct: 644 DEDIYEEGNYEEEGSEDVWEEGEDSDDSDLED 675



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 57/208 (27%), Positives = 111/208 (53%), Gaps = 22/208 (10%)

Query: 123 ISDDDNDDDNGNDLEVPD-DNSDDSEAPDDN--SDDSEAPDDNSDDSEAPDDNSDDSEAP 179
           I D +N D N    EVP+ + +D++E+ DD+  +D++E+ DDN+++ E  + N+DD+E  
Sbjct: 476 ICDSENPDHN----EVPNNETTDNNESADDHETTDNNESADDNNENPEDNNKNTDDNEEN 531

Query: 180 DDNSDDSDVPD----------DNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSS 229
            +N++++   +           N+ DSSD  SD+ +D+ SDD D   ++ D+    DD +
Sbjct: 532 PNNNENTYGNNFFKGGFWGSHGNNQDSSD--SDNEADEASDDEDNDGNEGDNEGSDDDGN 589

Query: 230 D-DSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDS 288
           + D++  DD   D E  +   +D +   D +D  +  +  SD+S   +   +  +  +D 
Sbjct: 590 EGDNEGSDDDDRDIEYYEKVIEDFD--KDQADYEDVIEIISDESVEEEGIEEGIQQDEDI 647

Query: 289 SDDSEASDDSSDDSEAPDDKSDDSDVPE 316
            ++    ++ S+D     + SDDSD+ +
Sbjct: 648 YEEGNYEEEGSEDVWEEGEDSDDSDLED 675



 Score = 80.5 bits (197), Expect = 5e-15
 Identities = 64/265 (24%), Positives = 127/265 (47%), Gaps = 24/265 (9%)

Query: 122 VISDDDNDDDNGNDLEVPD--DNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS-DDSEA 178
           + S+  + D+  +D+++ D  + +D  E  D+   D    ++N  DSE PD N   ++E 
Sbjct: 436 IFSEISDIDETIHDIKISDFMETTDYFETTDNEITDI---NENICDSENPDHNEVPNNET 492

Query: 179 PDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDS 238
            D+N    D    ++++S+DDN+++  D+N +  D  ++ +++ +   ++          
Sbjct: 493 TDNNESADDHETTDNNESADDNNENPEDNNKNTDDNEENPNNNENTYGNNFFKGGFWGSH 552

Query: 239 SDDSEAPDDSSDDSEAPDDSSDD-SEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDD 297
            ++ ++ D  ++  EA DD  +D +E  ++ SDD    D +  D+E SDD   D E  + 
Sbjct: 553 GNNQDSSDSDNEADEASDDEDNDGNEGDNEGSDD----DGNEGDNEGSDDDDRDIEYYEK 608

Query: 298 SSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEA 357
             +D +   D++D  DV E  SD+S   +   + ++     ED+  EG    +  E V  
Sbjct: 609 VIEDFD--KDQADYEDVIEIISDESVEEEGIEEGIQ---QDEDIYEEGNYEEEGSEDV-- 661

Query: 358 AAAVSQHDSSDDAGEQDLGENLSKP 382
                  +  +D+ + DL + L  P
Sbjct: 662 ------WEEGEDSDDSDLEDVLQVP 680



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 52/248 (20%), Positives = 120/248 (48%), Gaps = 30/248 (12%)

Query: 151 DNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSD 210
           +++ D  A +D   +    D+   D +   D  + +D  +   ++ +D N +    +N D
Sbjct: 425 EDAPDYYAVEDIFSEISDIDETIHDIKI-SDFMETTDYFETTDNEITDINENICDSENPD 483

Query: 211 DSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSD 270
            ++VP++++ D++   +S+DD +    ++D++E+ DD++++ E  + ++DD+E   ++++
Sbjct: 484 HNEVPNNETTDNN---ESADDHE----TTDNNESADDNNENPEDNNKNTDDNEENPNNNE 536

Query: 271 DSEAPD--------------DSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPE 316
           ++   +              DSSD    +D++SDD E +D +  D+E  DD  ++ D   
Sbjct: 537 NTYGNNFFKGGFWGSHGNNQDSSDSDNEADEASDD-EDNDGNEGDNEGSDDDGNEGDNEG 595

Query: 317 DKSDDSD-------VPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDD 369
              DD D       + D + D  +     E + +E       EE ++    + +  + ++
Sbjct: 596 SDDDDRDIEYYEKVIEDFDKDQADYEDVIEIISDESVEEEGIEEGIQQDEDIYEEGNYEE 655

Query: 370 AGEQDLGE 377
            G +D+ E
Sbjct: 656 EGSEDVWE 663



 Score = 30.4 bits (67), Expect = 5.7
 Identities = 16/93 (17%), Positives = 41/93 (44%)

Query: 124 SDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 183
           ++ DN+  + +D ++        +   D +D  +  +  SD+S   +   +  +  +D  
Sbjct: 589 NEGDNEGSDDDDRDIEYYEKVIEDFDKDQADYEDVIEIISDESVEEEGIEEGIQQDEDIY 648

Query: 184 DDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPD 216
           ++ +  ++ S+D  ++  D    D  D   VP+
Sbjct: 649 EEGNYEEEGSEDVWEEGEDSDDSDLEDVLQVPN 681


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 84/378 (22%), Positives = 153/378 (40%), Gaps = 34/378 (8%)

Query: 125  DDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD 184
            DD+  D  G DL+    + +  EA  D  D+    DD+ ++ E  +DN  +   P  + +
Sbjct: 4748 DDEKSDSEGGDLDKHMGDLNGEEA--DKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEE 4805

Query: 185  DSD-VPDDNSDDSSDDNSDDSSDDNSDDSD--VPDDKSDDSDVPDDSSDDSDVPDDSSDD 241
            DS+ V  D++ DS + N D S  D  ++ +    DD     D  ++  D+ D  ++  D 
Sbjct: 4806 DSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDP 4865

Query: 242  SEAPDDSSDDSEA---PDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDS 298
                 +   + EA   PDD + DSE   D +   +  ++  ++    +      EA  ++
Sbjct: 4866 YHGNQEKVPEPEALDLPDDLNLDSE---DKNGGEDTDNEEGEEENPLEIKEKPEEAGHEA 4922

Query: 299  SDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIAS-DEEELVEA 357
             +  E   D+ ++S  P++  +     D    + E+   A+D   +G  A   EE   E 
Sbjct: 4923 EERGETETDQ-NESQSPQEPEEGPSEDDKAEGEEEMDTGADD--QDGDAAQHPEEHSEEQ 4979

Query: 358  AAAVSQHD--SSDDAGEQDLGENLSKPPSDPEANPEVSERKLP--TEEEPAPVVEQSGKR 413
              +V + D  + ++ GE    +   +P  + E     +E ++P   E +      Q+G  
Sbjct: 4980 QQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVE 5039

Query: 414  KSKTKTIVE----PPRKRQTKTKNIVEPPRKRQTK--TKNIVEPLRKRKAKTKNVSVTPG 467
              +    +E     P K Q K ++        Q +    N +  L  +K   KN      
Sbjct: 5040 NMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQ---- 5095

Query: 468  HKKRGPSKKKPGAAKVEK 485
                   K+KPG A  E+
Sbjct: 5096 -----SFKRKPGQADNER 5108



 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 86/446 (19%), Positives = 186/446 (41%), Gaps = 41/446 (9%)

Query: 125  DDDNDDDNGNDLEVPDDNSDDSE--APDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDN 182
            +D+ ++DN  +   P  + +DSE  A DDN D   +  D S   +   +  +++EA D  
Sbjct: 4786 EDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDK--KEEKEEAEADDGG 4843

Query: 183  SDDSDVPDDNSDDSSDDNSDDSSDDNSDD------SDVPDD---KSDDSDVPDDSSDDSD 233
              +  + +   +   D+N  D    N +        D+PDD    S+D +  +D+ ++  
Sbjct: 4844 QGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEG 4903

Query: 234  VPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSE 293
              ++  +  E P+++  ++E   ++  D        +  E P   S+D +A  +   D+ 
Sbjct: 4904 EEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGP---SEDDKAEGEEEMDTG 4960

Query: 294  ASDDSSDDSEAPDDKSDDSDVP-EDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEE 352
            A D   D ++ P++ S++     E+K  ++D     +   +     ++   E +  SD E
Sbjct: 4961 ADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQE--EEEREDSDTE 5018

Query: 353  ELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGK 412
            E V  A    +H S    G +++    +   +   A PE  + K   EE  +   + +  
Sbjct: 5019 EQVPEALERKEHASCGQTGVENMQNTQAMELAG--AAPEKEQGK---EEHGSGAADANQA 5073

Query: 413  RKSKTKTIVEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRKAKTKNVSVTPGHKKRG 472
               ++  I +   ++ T+        +  Q   +  +    +R  K      T  H ++G
Sbjct: 5074 EGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQG 5133

Query: 473  PSKKKPGAAKVE--------KRKTRTPKCKVPGCFLQDLEKSKKYSGKNLKRNKDELVQR 524
            P+++    A+VE        K+ +     +      ++ ++S K SGK+  + ++E+   
Sbjct: 5134 PAQQP--QAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKD--QEEEEIEDT 5189

Query: 525  IYDL-----FNRSVCDKKLPEKLRIG 545
            + D      F  +  ++  PE+++ G
Sbjct: 5190 LMDTEEQEEFKAADVEQLKPEEIKSG 5215



 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 61/288 (21%), Positives = 115/288 (39%), Gaps = 33/288 (11%)

Query: 126  DDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD-DSEAPDDNSD 184
            D  D D+ +D++  D+  + SE  D    D E  +   DD ++  +  D D    D N +
Sbjct: 4710 DKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGE 4769

Query: 185  DSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEA 244
            ++D  D+      D+  D+  +DN  +   P    +DS++   + DD+    +S+ D   
Sbjct: 4770 EADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELV--AKDDNLDSGNSNKDKSQ 4827

Query: 245  PDDSSDDSEA-PDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSE 303
             D   +  EA  DD     +  ++  D+ +  ++  D    + +   + EA D       
Sbjct: 4828 QDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALD------- 4880

Query: 304  APDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQ 363
             PDD + DS+      D  +   +  + LE+    E+  +E                   
Sbjct: 4881 LPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHE------------------- 4921

Query: 364  HDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSG 411
               +++ GE +  +N S+ P +PE  P   ++    EE      +Q G
Sbjct: 4922 ---AEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDG 4966



 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 55/255 (21%), Positives = 108/255 (42%), Gaps = 23/255 (9%)

Query: 82   DSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGN-DLEVPD 140
            D +EE    E+ K +      D+E  E            +V  DD+ D  N N D    D
Sbjct: 4782 DDEEEDEEEEDNKTEETGPGMDEEDSE------------LVAKDDNLDSGNSNKDKSQQD 4829

Query: 141  DNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDD----SEAPDDNSDDSDVPDDNSDDS 196
               +  EA  D+    E   +   D    D+N  D    ++      +  D+PDD + DS
Sbjct: 4830 KKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDS 4889

Query: 197  SDDNSDDSSDDNSDDSDVP---DDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDS-SDDS 252
             D N  + +D+   + + P    +K +++    +   +++   + S   + P++  S+D 
Sbjct: 4890 EDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDD 4949

Query: 253  EAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDD-KSDD 311
            +A  +   D+ A D   D ++ P++ S++ + S +  D  EA ++  ++  A    +  +
Sbjct: 4950 KAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKD-KEADEEGGENGPADQGFQPQE 5008

Query: 312  SDVPEDKSDDSDVPD 326
             +  ED   +  VP+
Sbjct: 5009 EEEREDSDTEEQVPE 5023



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 63/305 (20%), Positives = 111/305 (36%), Gaps = 30/305 (9%)

Query: 188  VPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDD 247
            +P +  +DS+ + + +  D         +   D SD   +     D      +  +   D
Sbjct: 4656 LPKEFMEDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPD 4715

Query: 248  SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSD-DSEASD------DSSD 300
            S  D +  D++ + SE  D    D E  +   DD ++  +  D D    D      D  D
Sbjct: 4716 SKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLD 4775

Query: 301  DSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDL----CNEGQIASDEEELVE 356
            +    DD  ++ +  ED   +   P  + +D E+    ++L     N+ +   D++E  E
Sbjct: 4776 ERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKE 4835

Query: 357  AAAAVSQHDSSDDAGEQ----DLGENLSKP-PSDPEANPEVSERKLPTEEEPAPVVEQSG 411
             A A       D   EQ    D  EN   P   + E  PE     LP +       +  G
Sbjct: 4836 EAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGG 4895

Query: 412  KRKSKTKTIVEPPRKRQTKTKNIVEPPRKR-QTKTKNIVEPLRKRKAKTKNVSVTPGHKK 470
            +     +   E P + + K +       +R +T+T              +N S +P   +
Sbjct: 4896 EDTDNEEGEEENPLEIKEKPEEAGHEAEERGETET-------------DQNESQSPQEPE 4942

Query: 471  RGPSK 475
             GPS+
Sbjct: 4943 EGPSE 4947


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 80.5 bits (197), Expect = 5e-15
 Identities = 86/383 (22%), Positives = 146/383 (38%), Gaps = 41/383 (10%)

Query: 139  PDDNSDDSEA--PDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD---------DSD 187
            P + S+ SE   P  ++   E  DD   + EA +     ++ P  + +          S 
Sbjct: 900  PSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSF 959

Query: 188  VPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDD 247
              D   +++S ++S +  +++ ++ +  +D+ +  D     ++ SD  D+ S DS +   
Sbjct: 960  ALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEES-DSSSKCS 1018

Query: 248  SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDD 307
               DS+  +DS+ DSE+   SS  S     SS  S +S  SS  SE+S +  ++ E P  
Sbjct: 1019 LYADSDGENDSTSDSESSSSSSSSS-----SSSSSSSSSSSSSSSESSSEDEEEEERP-- 1071

Query: 308  KSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSS 367
                + +P       +VP      +EVPVP E +         E+E   A  A    +S 
Sbjct: 1072 ----AALPSASPPPREVPVPTPAPVEVPVP-ERVAGSPVTPLPEQEASPARPAGPTEESP 1126

Query: 368  DDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKS-------KTKTI 420
              A          +PP  P   P  + R       P P++    KR+        +    
Sbjct: 1127 PSAP--------LRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPA 1178

Query: 421  VEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRKAKTKNVSVTPGHKKRGPSKKKPGA 480
             EPP     + K      RK     +  +  L    A    V   P    RG   +  G 
Sbjct: 1179 PEPPPATPPQAKFPGPASRKAPRGVERTIRNLPLDHASL--VKSWPEEVSRGGRSRAGGR 1236

Query: 481  AKVEKRKTRTPKCKVPGCFLQDL 503
             ++ + +   P  +V    L DL
Sbjct: 1237 GRLTEEEEAEPGTEVDLAVLADL 1259



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 43/209 (20%), Positives = 87/209 (41%), Gaps = 33/209 (15%)

Query: 218  KSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSD------- 270
            + + S++ + S +    P   +++ E  DD   + EA +     ++ P    +       
Sbjct: 897  RKEPSEISEASEEKRPRPSTPAEEDE--DDPEQEKEAGEPGRPGTKPPKRDEERGKTQGK 954

Query: 271  -------DSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSD 323
                   DSE  + S + S   D+  +D E  ++  D  EA D    +++V + + ++SD
Sbjct: 955  HRKSFALDSEGEEASQESSSEKDE--EDDEEDEEDEDREEAVDTTKKETEVSDGEDEESD 1012

Query: 324  VPD------DNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGE 377
                     D+  + +    +E   +    +S       ++++ S   SS+D  E++   
Sbjct: 1013 SSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEE--- 1069

Query: 378  NLSKPPSDPEANPEVSERKLPTEEEPAPV 406
               +P + P A+P   E  +PT   PAPV
Sbjct: 1070 ---RPAALPSASPPPREVPVPT---PAPV 1092



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 42/167 (25%), Positives = 73/167 (43%), Gaps = 21/167 (12%)

Query: 84   DEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNS 143
            DEE    + K  K   ++S+ E         A QE     S+ D +DD     E  +++ 
Sbjct: 945  DEERGKTQGKHRKSFALDSEGEE--------ASQESS---SEKDEEDD-----EEDEEDE 988

Query: 144  DDSEAPDDNSDDSEAPDDNSDDSEAPDDNS--DDSEAPDDNSDDSDVPDDNSDDSSDDNS 201
            D  EA D    ++E  D   ++S++    S   DS+  +D++ DS+    +S  SS  +S
Sbjct: 989  DREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSS 1048

Query: 202  DDSSDDNSDDSDVPDDKSDD---SDVPDDSSDDSDVPDDSSDDSEAP 245
              SS  +S      +D+ ++   + +P  S    +VP  +    E P
Sbjct: 1049 SSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVP 1095



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 39/196 (19%), Positives = 75/196 (38%), Gaps = 11/196 (5%)

Query: 126  DDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS-- 183
            ++   ++ ++ +  DD  D     +++ D  EA D    ++E  D   ++S++    S  
Sbjct: 966  EEASQESSSEKDEEDDEED-----EEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLY 1020

Query: 184  DDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDD---SDVPDDSSD 240
             DSD  +D++ DS   +S  SS  +S  S      S      +D  ++   + +P  S  
Sbjct: 1021 ADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPP 1080

Query: 241  DSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSD 300
              E P  +    E P              +   +P   +  +E S  S+        +  
Sbjct: 1081 PREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGP 1140

Query: 301  DSEAP-DDKSDDSDVP 315
             + AP  D+   S +P
Sbjct: 1141 PAPAPRPDERPSSPIP 1156



 Score = 31.6 bits (70), Expect = 2.6
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 5/86 (5%)

Query: 212 SDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSE--APDDSSDDS---EAPD 266
           SD  +++ + S V       S+VP  S      P  +  + E  AP  S +     E+P 
Sbjct: 508 SDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPK 567

Query: 267 DSSDDSEAPDDSSDDSEASDDSSDDS 292
            +  +  +P  S DD E SDD    S
Sbjct: 568 ANGQNQASPCSSGDDMEISDDDRGGS 593



 Score = 29.6 bits (65), Expect = 9.8
 Identities = 24/89 (26%), Positives = 34/89 (38%), Gaps = 5/89 (5%)

Query: 222 SDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSE--APDDSSDDS---EAPD 276
           SD  ++  + S V       SE P  S      P  +  + E  AP  S +     E+P 
Sbjct: 508 SDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPK 567

Query: 277 DSSDDSEASDDSSDDSEASDDSSDDSEAP 305
            +  +  +   S DD E SDD    S  P
Sbjct: 568 ANGQNQASPCSSGDDMEISDDDRGGSPPP 596


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 80.5 bits (197), Expect = 5e-15
 Identities = 89/377 (23%), Positives = 153/377 (40%), Gaps = 47/377 (12%)

Query: 78  VIDSDSDEECHTH---EEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGN 134
           V DS++DE  + +    E +    + +SD ES E         EPP   S++++ + +G+
Sbjct: 66  VTDSENDEPLNLNASDSESEELHRQKDSDSESEERA-------EPPASDSENEDVNQHGS 118

Query: 135 DLE------VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDV 188
           D E      +P  +S++ E  + ++ DSE    N D  + P  +S+  E     + DS+ 
Sbjct: 119 DSESEETRKLPGSDSENEELLNGHASDSE----NEDVGKHPASDSEIEELQKSPASDSET 174

Query: 189 PDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAP--- 245
            D      SD  S++     + DS+  +++     + D  S++   P  S  +SE P   
Sbjct: 175 EDALKPQISDSESEEPPRHQASDSE--NEEPPKPRMSDSESEELPKPQVSDSESEEPPRH 232

Query: 246 ---DDSSDDSEAPDDSSDDSEAPD----DSSDDSEAPDDSSDDSEASDDSSDDSEASDDS 298
              D  +++   P  S  +SE P       S++ E P     DSE+ D     ++ASD  
Sbjct: 233 QASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPR--NQASDSE 290

Query: 299 SDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAA 358
           +++   P     +S+ P+         +D S   + P   +D        SD E   E  
Sbjct: 291 NEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDD--------SDRENKGEDT 342

Query: 359 AAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTK 418
               Q+DS       D  +  S   SD E      ++    E+E     E+  KRK+   
Sbjct: 343 E--MQNDSFHSDSHMDRKKFHS---SDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVL 397

Query: 419 TIVEPPRKRQTKTKNIV 435
           +  E   K   K   +V
Sbjct: 398 SDSEDEEKASAKKSRVV 414



 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 86/351 (24%), Positives = 149/351 (42%), Gaps = 64/351 (18%)

Query: 63  SVARRAPKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAI-----Q 117
           S +   P+ QAS       DS+ E    E  K ++    SD ES E    KP +     +
Sbjct: 185 SESEEPPRHQAS-------DSENE----EPPKPRM----SDSESEEL--PKPQVSDSESE 227

Query: 118 EPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPD------DNSDDSEAPDDNSDDSEAPD- 170
           EPP   + D  ++      E+P     DSE+ D       +S++ E P     DSE+ D 
Sbjct: 228 EPPRHQASDSENE------ELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDP 281

Query: 171 -----DNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSS-----DDNSDDSDVPDDKSD 220
                 +S++ E P     DS+        +SD  ++D+S      ++ DDSD  ++K +
Sbjct: 282 PRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSD-RENKGE 340

Query: 221 DSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAP--DDS 278
           D+++ +DS       D     S   ++     +  D   D+ E  ++     +A    DS
Sbjct: 341 DTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDS 400

Query: 279 SDDSEASDDSSDDSEASDDSSDDSEAPDDKSD--DSDVPEDKSDDS--DVPDDNSDDLEV 334
            D+ +AS   S     +DDS  DS+A  DKS   +  +  D  +++  ++ D  +++ ++
Sbjct: 401 EDEEKASAKKSRVVSDADDS--DSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDL 458

Query: 335 PVPAEDLCNEGQ--------IASDEEELVEAAAAVSQHDSSDDAGEQDLGE 377
                +  NE +         + DEEE  E     +Q D  ++ GE  + E
Sbjct: 459 FGSDSESGNEEENLIADIFGESGDEEE--EEFTGFNQEDLEEEKGETQVKE 507



 Score = 73.6 bits (179), Expect = 6e-13
 Identities = 78/357 (21%), Positives = 143/357 (40%), Gaps = 40/357 (11%)

Query: 124 SDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 183
           S D +DD  G    V D+    S+  DD ++     D  S +  + ++ SD  +      
Sbjct: 7   SGDQSDD--GGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGH 64

Query: 184 DDSDVPDD-----NSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDS 238
             +D  +D     N+ DS  +      D +S+  +  +  + DS+  D +   SD   +S
Sbjct: 65  HVTDSENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSD--SES 122

Query: 239 SDDSEAPDDSSDDSEAPDDSSDDSEAPD-DSSDDSEAPDDSSDDSEASDDSSDDSEASDD 297
            +  + P   S++ E  +  + DSE  D      S++  +    S ASD  ++D+     
Sbjct: 123 EETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQI 182

Query: 298 SSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEA 357
           S  +SE P  +   SD   ++     + D  S++L  P          Q++  E E    
Sbjct: 183 SDSESEEP-PRHQASDSENEEPPKPRMSDSESEELPKP----------QVSDSESE---- 227

Query: 358 AAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKT 417
                +H +SD   E+     +S   S+     + S+ +   EE P P +  S       
Sbjct: 228 --EPPRHQASDSENEELPKPRISDSESEDPPRHQASDSE--NEELPKPRISDSESE---- 279

Query: 418 KTIVEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRKAKTKNVSVTPGHKKRGPS 474
               +PPR + + ++N  E P+ R + +++  E  +K  A          HK++  S
Sbjct: 280 ----DPPRNQASDSEN-EELPKPRVSDSES--EGPQKGPASDSETEDASRHKQKPES 329



 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 82/371 (22%), Positives = 144/371 (38%), Gaps = 59/371 (15%)

Query: 12  QEPEEDEDCYILNVQSSSDDTS--------GSSVARRAPKRQASCILNVQSRSGDTSGSS 63
           + P  D +   L    +SD  +          S +   P+ QAS   N +      S S 
Sbjct: 153 KHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSE 212

Query: 64  VARRAPKRQASSVVVIDSDSDE-------ECHTHEEKKAKLLEINSDDESPECCHVKPAI 116
            +   PK Q S     DS+S+E       +    E  K ++ +  S+D            
Sbjct: 213 -SEELPKPQVS-----DSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENE 266

Query: 117 QEPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDN-SDDSEAPDDN--- 172
           + P   ISD +++D   N  +  D  +++   P  +  +SE P    + DSE  D +   
Sbjct: 267 ELPKPRISDSESEDPPRN--QASDSENEELPKPRVSDSESEGPQKGPASDSETEDASRHK 324

Query: 173 ----SDDSEAPDDNSDDSDVPDDN--------------SDDSSDDNSDDSSDDNSDDSDV 214
               SDD    ++  +D+++ +D+              SD   +++     D + D+ + 
Sbjct: 325 QKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEG 384

Query: 215 PDDK---------SDDSDVPDDSSDDSDVPDDSSD-DSEAPDDSSDDSEAPDDSSDDSEA 264
            ++K         SD  D    S+  S V  D+ D DS+A  D S   E    S  + EA
Sbjct: 385 EEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEA 444

Query: 265 PDDSSDDSEAPDD--SSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDD- 321
             + SD      D   SD    +++ +  ++   +S D+ E      +  D+ E+K +  
Sbjct: 445 GKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKGETQ 504

Query: 322 -SDVPDDNSDD 331
             +  D +SDD
Sbjct: 505 VKEAEDSDSDD 515



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 71/315 (22%), Positives = 140/315 (44%), Gaps = 36/315 (11%)

Query: 200 NSDDSSDDNSDD---SDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPD 256
           +S+  S D SDD   + V D++   SD  DD ++     D  S +  + +++SD  +   
Sbjct: 2   DSEYYSGDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLP 61

Query: 257 DSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSE------ASDDSSDD--SEAPDDK 308
                +++ +D   +  A D  S++     DS  +SE      ASD  ++D      D +
Sbjct: 62  KGHHVTDSENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSE 121

Query: 309 SDDS-DVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSS 367
           S+++  +P   S++ ++ + ++ D E     ED+       S+ EEL ++ A+ S+   +
Sbjct: 122 SEETRKLPGSDSENEELLNGHASDSE----NEDVGKHPASDSEIEELQKSPASDSE---T 174

Query: 368 DDAGEQDLGENLSKPP-------SDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTI 420
           +DA +  + ++ S+ P       S+ E  P+       +EE P P V  S          
Sbjct: 175 EDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESE------- 227

Query: 421 VEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRKAKTKNVSVTPGHKKRGPSKKKPGA 480
            EPPR + + ++N  E P+ R + +++  +P R + + ++N  +         S+  P  
Sbjct: 228 -EPPRHQASDSEN-EELPKPRISDSES-EDPPRHQASDSENEELPKPRISDSESEDPPRN 284

Query: 481 AKVEKRKTRTPKCKV 495
              +      PK +V
Sbjct: 285 QASDSENEELPKPRV 299



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 93/405 (22%), Positives = 156/405 (38%), Gaps = 52/405 (12%)

Query: 2   DGCKKELPRLQEPEEDEDCYILNVQSSSDDTS------GSSVARRAPKRQASCILNVQSR 55
           D   +ELP+ Q  + + +    +  S S++          S +   P+ QAS   N +  
Sbjct: 210 DSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELP 269

Query: 56  SGDTSGSSVARRAPKRQASSVVVIDSDSDEECH---THEEKKAKLLEINSDDESPECCHV 112
               S S  +   P+ QAS     DS+++E      +  E +       SD E+ +    
Sbjct: 270 KPRISDSE-SEDPPRNQAS-----DSENEELPKPRVSDSESEGPQKGPASDSETEDASRH 323

Query: 113 KPAIQEPPIVISDDDNDDDN-GNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDD 171
           K   Q+P    SDDD+D +N G D E+ +D+       D     S   ++     +  D 
Sbjct: 324 K---QKPE---SDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDS 377

Query: 172 NSDDSEAPDDN--SDDSDVPDDNSDD--SSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDD 227
           + D+ E  ++      + V  D+ D+  +S   S   SD +  DSD   DKS   +    
Sbjct: 378 DEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGKREKTIA 437

Query: 228 SSDDSDVPDDSSDD-SEAPDDSSDDSEAPDDSSD---DSEAPDDSSDDSEAPDDSSDDSE 283
           S  + +   + SD  +E  D    DSE+ ++  +   D        ++ E    + +D E
Sbjct: 438 SDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLE 497

Query: 284 ASDDSSDDSEASDDSSDDS----EAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAE 339
                +   EA D  SDD+    +  D  SD   + + K   S     N D         
Sbjct: 498 EEKGETQVKEAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMSGKRRRNRDG-------- 549

Query: 340 DLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPS 384
                G   SD +++V A          ++A E+D   N  K P+
Sbjct: 550 -----GTFISDADDVVSAMIV-----KMNEAAEEDRQLNNQKKPA 584



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 77/330 (23%), Positives = 127/330 (38%), Gaps = 36/330 (10%)

Query: 9   PRLQEPEEDEDCYILNVQSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRA 68
           PR+ + E +E    L     SD  S        P+ QAS   N +      S S  +   
Sbjct: 206 PRMSDSESEE----LPKPQVSDSES-----EEPPRHQASDSENEELPKPRISDSE-SEDP 255

Query: 69  PKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDN 128
           P+ QAS       DS+ E    E  K ++ +  S+D            + P   +SD ++
Sbjct: 256 PRHQAS-------DSENE----ELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSES 304

Query: 129 DDDN---GNDLEVPDDN-------SDDSEAPDDNSDDSEAPDDNSDDSEAPDD---NSDD 175
           +       +D E  D +       SDD    ++  +D+E  +D+       D    +S D
Sbjct: 305 EGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSD 364

Query: 176 SEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSD-DSDV 234
           SE  +      D  +D  +   +  +   +   SD  D     +  S V  D+ D DSD 
Sbjct: 365 SEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDA 424

Query: 235 PDDSSDDSEAPDDSSDDSEAPDDSSD-DSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSE 293
             D S   E    S  + EA  + SD  +E  D    DSE+ ++  +        S D E
Sbjct: 425 VSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEE 484

Query: 294 ASDDSSDDSEAPDDKSDDSDVPEDKSDDSD 323
             + +  + E  +++  ++ V E +  DSD
Sbjct: 485 EEEFTGFNQEDLEEEKGETQVKEAEDSDSD 514


>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 80/363 (22%), Positives = 158/363 (43%), Gaps = 45/363 (12%)

Query: 28  SSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQASSVVVIDSDSDEEC 87
           S+ + +G S AR   +  ++  +N Q      + + +A   P  +       D    EE 
Sbjct: 389 SASERAGPSRARHFSEHPSTSKMNAQE-----TATGMAFEEPIDEKKFEKTEDGGEFEEG 443

Query: 88  HTHEEKKAKLLEINSDDESPECCHVKPAIQEPP---IVISDDDNDDDNGNDLEVPDDNSD 144
            +    K    E + + E+ E C  K + +  P      S    + + GN +   +++S 
Sbjct: 444 ASENNAK----ESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSP 499

Query: 145 DSEAP--------DDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDS 196
             E+         ++N    E+ DD + +SE     + +SE  DD+  +SD  +D S+  
Sbjct: 500 KKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEE-DDSEKESD--EDCSEKQ 556

Query: 197 SDDNSDDSSDDNSDDSDVPDDKSD--------DSDVPDDSSDDSDVPDDSSDDSEAPDDS 248
           S+D S+   ++N  + D+ ++ S+        D ++ ++ S++S+  DD S+  +  D+ 
Sbjct: 557 SEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSE--KVLDEE 614

Query: 249 SDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDK 308
             + E  +DS +  E  D      +   D  +D E +D+     EA+D  +++ +A +  
Sbjct: 615 GSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKG--LEAADKKAEEGDADEKL 672

Query: 309 SDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSD 368
            ++SD  ED+  D    +D  + L      ED  +  ++  +EE+  E        D SD
Sbjct: 673 FEESDDKEDEDADGKEVEDADEKL-----FEDDDSNEKLFDEEEDSSE-----KLFDDSD 722

Query: 369 DAG 371
           + G
Sbjct: 723 ERG 725



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 62/244 (25%), Positives = 109/244 (44%), Gaps = 26/244 (10%)

Query: 79  IDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEV 138
           ++ +S+EE    +E +    E +S+ ES E C  K +         D    +   N LE 
Sbjct: 525 LNKESEEEVGPTKESE----EDDSEKESDEDCSEKQS--------EDGSEREFEENGLEK 572

Query: 139 PDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD---DSEAP----DDNSDDSDVPDD 191
             D     +   +N  D E  +++S++SE  DD S+   D E      D++SD+ +  +D
Sbjct: 573 DLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEED 632

Query: 192 NSDDSSDDNSDDSSDDNSDDS---DVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDS 248
             +   DD SD+  D+   D    +  D K+++ D  +   ++SD  +D   D +  +D+
Sbjct: 633 TYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDA 692

Query: 249 SDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDD--SEASDDSSDDSEASDDSSDDSEAPD 306
            +     DDS++  +  D+  D SE   D SD+  +     S ++   S  SS    + D
Sbjct: 693 DEKLFEDDDSNE--KLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSSDD 750

Query: 307 DKSD 310
           D  D
Sbjct: 751 DDDD 754



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 61/296 (20%), Positives = 123/296 (41%), Gaps = 18/296 (6%)

Query: 118 EPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSE 177
           E PI     +  +D G   E   +N+    +P+  +++   P+  S++   P    + S 
Sbjct: 423 EEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEG-CPEKESEEG-CPKRGFEGSC 480

Query: 178 APDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDD 237
           +  ++ + + V     D    ++   +  ++ +++ +  +  DD +  +   +     + 
Sbjct: 481 SQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLN-KESEEEVGPTKES 539

Query: 238 SSDDSEAPDDSSDDSEAPDDSSDDS------EAPDDSSDDSEAPDDSSDDSEASDDSSDD 291
             DDSE   D     +  +D S+        E   D     +   ++  D E  ++ S++
Sbjct: 540 EEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSEN 599

Query: 292 SEASDDSSD---DSEAPDDKSD-DSDVPEDKSDDSD-VPDDNSDDLEVPVPAEDLCNEGQ 346
           SE  DD S+   D E  + + D DSD  E++ D  + V DD SD+ E     E+  +E  
Sbjct: 600 SEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKE----DEEYADEKG 655

Query: 347 IASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEE 402
           + + +++  E  A     + SDD  ++D      +   +     + S  KL  EEE
Sbjct: 656 LEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEE 711



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 49/260 (18%), Positives = 104/260 (40%), Gaps = 8/260 (3%)

Query: 157 EAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPD 216
           E  +D  +  E   +N+    +P+  +++   P+  S++       + S    +  +   
Sbjct: 432 EKTEDGGEFEEGASENNAKESSPEKEAEEG-CPEKESEEGCPKRGFEGSCSQKESEEGNP 490

Query: 217 DKSDDSDVPDDSSDDSDVPDDSSDDS---EAPDDSSDDSEAPDDSSDDSEAPDDSSD-DS 272
            +  + D P   S    + +D  ++    E+ DD + +SE     + +SE  D   + D 
Sbjct: 491 VRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDE 550

Query: 273 EAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDL 332
           +  +  S+D    +   +  E   D     +   +   D ++ E+ S++S+  DD S+ +
Sbjct: 551 DCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKV 610

Query: 333 EVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEV 392
              +  E    E    SDE+E  E        D SD+  +++  +      +D +A    
Sbjct: 611 ---LDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGD 667

Query: 393 SERKLPTEEEPAPVVEQSGK 412
           ++ KL  E +     +  GK
Sbjct: 668 ADEKLFEESDDKEDEDADGK 687



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 49/266 (18%), Positives = 106/266 (39%), Gaps = 15/266 (5%)

Query: 136 LEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDD 195
           L  P+ N     +   ++ +   P      SE P  +  +++         +  D+   +
Sbjct: 373 LNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFE 432

Query: 196 SSDDNSD---DSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDS 252
            ++D  +    +S++N+ +S    +K  +   P+  S++   P    + S +  +S + +
Sbjct: 433 KTEDGGEFEEGASENNAKESS--PEKEAEEGCPEKESEEG-CPKRGFEGSCSQKESEEGN 489

Query: 253 EAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPD-DKSDD 311
                  D  +            +++    E+ DD + +SE     + +SE  D +K  D
Sbjct: 490 PVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESD 549

Query: 312 SDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSS---D 368
            D  E +S+D    +   + LE     +DL  EG      E +++     +  ++S   D
Sbjct: 550 EDCSEKQSEDGSEREFEENGLE-----KDLDEEGSEKELHENVLDKELEENDSENSEFED 604

Query: 369 DAGEQDLGENLSKPPSDPEANPEVSE 394
           D  E+ L E  S+   D +++ +  E
Sbjct: 605 DGSEKVLDEEGSEREFDEDSDEKEEE 630



 Score = 37.0 bits (84), Expect = 0.061
 Identities = 48/224 (21%), Positives = 91/224 (40%), Gaps = 25/224 (11%)

Query: 13  EPEEDEDCYILNVQSSSDDTSGSSVARR------APKRQASCILNVQSRSGDTSGSSVAR 66
           E E DEDC     +  S+     +   +      + K     +L+ +    D+  S    
Sbjct: 545 EKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFED 604

Query: 67  RAPKR---QASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVI 123
              ++   +  S    D DSDE+    E+   K+ +  SD++  E    +  ++      
Sbjct: 605 DGSEKVLDEEGSEREFDEDSDEK-EEEEDTYEKVFDDESDEKEDEEYADEKGLEAA---- 659

Query: 124 SDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 183
              D   + G+  E   + SDD E  D+++D  E  D  +D+    DD+S++ +  D+  
Sbjct: 660 ---DKKAEEGDADEKLFEESDDKE--DEDADGKEVED--ADEKLFEDDDSNE-KLFDEEE 711

Query: 184 DDSDVPDDNSDDSSDDNSDDSSDD---NSDDSDVPDDKSDDSDV 224
           D S+   D+SD+        S ++   ++  S +     DD D+
Sbjct: 712 DSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSSDDDDDDI 755


>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 80/363 (22%), Positives = 158/363 (43%), Gaps = 45/363 (12%)

Query: 28  SSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQASSVVVIDSDSDEEC 87
           S+ + +G S AR   +  ++  +N Q      + + +A   P  +       D    EE 
Sbjct: 389 SASERAGPSRARHFSEHPSTSKMNAQE-----TATGMAFEEPIDEKKFEKTEDGGEFEEG 443

Query: 88  HTHEEKKAKLLEINSDDESPECCHVKPAIQEPP---IVISDDDNDDDNGNDLEVPDDNSD 144
            +    K    E + + E+ E C  K + +  P      S    + + GN +   +++S 
Sbjct: 444 ASENNAK----ESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSP 499

Query: 145 DSEAP--------DDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDS 196
             E+         ++N    E+ DD + +SE     + +SE  DD+  +SD  +D S+  
Sbjct: 500 KKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEE-DDSEKESD--EDCSEKQ 556

Query: 197 SDDNSDDSSDDNSDDSDVPDDKSD--------DSDVPDDSSDDSDVPDDSSDDSEAPDDS 248
           S+D S+   ++N  + D+ ++ S+        D ++ ++ S++S+  DD S+  +  D+ 
Sbjct: 557 SEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSE--KVLDEE 614

Query: 249 SDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDK 308
             + E  +DS +  E  D      +   D  +D E +D+     EA+D  +++ +A +  
Sbjct: 615 GSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKG--LEAADKKAEEGDADEKL 672

Query: 309 SDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSD 368
            ++SD  ED+  D    +D  + L      ED  +  ++  +EE+  E        D SD
Sbjct: 673 FEESDDKEDEDADGKEVEDADEKL-----FEDDDSNEKLFDEEEDSSE-----KLFDDSD 722

Query: 369 DAG 371
           + G
Sbjct: 723 ERG 725



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 62/244 (25%), Positives = 109/244 (44%), Gaps = 26/244 (10%)

Query: 79  IDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEV 138
           ++ +S+EE    +E +    E +S+ ES E C  K +         D    +   N LE 
Sbjct: 525 LNKESEEEVGPTKESE----EDDSEKESDEDCSEKQS--------EDGSEREFEENGLEK 572

Query: 139 PDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD---DSEAP----DDNSDDSDVPDD 191
             D     +   +N  D E  +++S++SE  DD S+   D E      D++SD+ +  +D
Sbjct: 573 DLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEED 632

Query: 192 NSDDSSDDNSDDSSDDNSDDS---DVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDS 248
             +   DD SD+  D+   D    +  D K+++ D  +   ++SD  +D   D +  +D+
Sbjct: 633 TYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDA 692

Query: 249 SDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDD--SEASDDSSDDSEASDDSSDDSEAPD 306
            +     DDS++  +  D+  D SE   D SD+  +     S ++   S  SS    + D
Sbjct: 693 DEKLFEDDDSNE--KLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSSDD 750

Query: 307 DKSD 310
           D  D
Sbjct: 751 DDDD 754



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 61/296 (20%), Positives = 123/296 (41%), Gaps = 18/296 (6%)

Query: 118 EPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSE 177
           E PI     +  +D G   E   +N+    +P+  +++   P+  S++   P    + S 
Sbjct: 423 EEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEG-CPEKESEEG-CPKRGFEGSC 480

Query: 178 APDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDD 237
           +  ++ + + V     D    ++   +  ++ +++ +  +  DD +  +   +     + 
Sbjct: 481 SQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLN-KESEEEVGPTKES 539

Query: 238 SSDDSEAPDDSSDDSEAPDDSSDDS------EAPDDSSDDSEAPDDSSDDSEASDDSSDD 291
             DDSE   D     +  +D S+        E   D     +   ++  D E  ++ S++
Sbjct: 540 EEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSEN 599

Query: 292 SEASDDSSD---DSEAPDDKSD-DSDVPEDKSDDSD-VPDDNSDDLEVPVPAEDLCNEGQ 346
           SE  DD S+   D E  + + D DSD  E++ D  + V DD SD+ E     E+  +E  
Sbjct: 600 SEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKE----DEEYADEKG 655

Query: 347 IASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEE 402
           + + +++  E  A     + SDD  ++D      +   +     + S  KL  EEE
Sbjct: 656 LEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEE 711



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 49/260 (18%), Positives = 104/260 (40%), Gaps = 8/260 (3%)

Query: 157 EAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPD 216
           E  +D  +  E   +N+    +P+  +++   P+  S++       + S    +  +   
Sbjct: 432 EKTEDGGEFEEGASENNAKESSPEKEAEEG-CPEKESEEGCPKRGFEGSCSQKESEEGNP 490

Query: 217 DKSDDSDVPDDSSDDSDVPDDSSDDS---EAPDDSSDDSEAPDDSSDDSEAPDDSSD-DS 272
            +  + D P   S    + +D  ++    E+ DD + +SE     + +SE  D   + D 
Sbjct: 491 VRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDE 550

Query: 273 EAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDL 332
           +  +  S+D    +   +  E   D     +   +   D ++ E+ S++S+  DD S+ +
Sbjct: 551 DCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKV 610

Query: 333 EVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEV 392
              +  E    E    SDE+E  E        D SD+  +++  +      +D +A    
Sbjct: 611 ---LDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGD 667

Query: 393 SERKLPTEEEPAPVVEQSGK 412
           ++ KL  E +     +  GK
Sbjct: 668 ADEKLFEESDDKEDEDADGK 687



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 49/266 (18%), Positives = 106/266 (39%), Gaps = 15/266 (5%)

Query: 136 LEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDD 195
           L  P+ N     +   ++ +   P      SE P  +  +++         +  D+   +
Sbjct: 373 LNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFE 432

Query: 196 SSDDNSD---DSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDS 252
            ++D  +    +S++N+ +S    +K  +   P+  S++   P    + S +  +S + +
Sbjct: 433 KTEDGGEFEEGASENNAKESS--PEKEAEEGCPEKESEEG-CPKRGFEGSCSQKESEEGN 489

Query: 253 EAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPD-DKSDD 311
                  D  +            +++    E+ DD + +SE     + +SE  D +K  D
Sbjct: 490 PVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESD 549

Query: 312 SDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSS---D 368
            D  E +S+D    +   + LE     +DL  EG      E +++     +  ++S   D
Sbjct: 550 EDCSEKQSEDGSEREFEENGLE-----KDLDEEGSEKELHENVLDKELEENDSENSEFED 604

Query: 369 DAGEQDLGENLSKPPSDPEANPEVSE 394
           D  E+ L E  S+   D +++ +  E
Sbjct: 605 DGSEKVLDEEGSEREFDEDSDEKEEE 630



 Score = 37.0 bits (84), Expect = 0.061
 Identities = 48/224 (21%), Positives = 91/224 (40%), Gaps = 25/224 (11%)

Query: 13  EPEEDEDCYILNVQSSSDDTSGSSVARR------APKRQASCILNVQSRSGDTSGSSVAR 66
           E E DEDC     +  S+     +   +      + K     +L+ +    D+  S    
Sbjct: 545 EKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFED 604

Query: 67  RAPKR---QASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVI 123
              ++   +  S    D DSDE+    E+   K+ +  SD++  E    +  ++      
Sbjct: 605 DGSEKVLDEEGSEREFDEDSDEK-EEEEDTYEKVFDDESDEKEDEEYADEKGLEAA---- 659

Query: 124 SDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 183
              D   + G+  E   + SDD E  D+++D  E  D  +D+    DD+S++ +  D+  
Sbjct: 660 ---DKKAEEGDADEKLFEESDDKE--DEDADGKEVED--ADEKLFEDDDSNE-KLFDEEE 711

Query: 184 DDSDVPDDNSDDSSDDNSDDSSDD---NSDDSDVPDDKSDDSDV 224
           D S+   D+SD+        S ++   ++  S +     DD D+
Sbjct: 712 DSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSSDDDDDDI 755


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 54/252 (21%), Positives = 113/252 (44%), Gaps = 27/252 (10%)

Query: 82  DSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDND--DDNGNDLEVP 139
           ++ E+ +T +   ++LLE           H    I     +  +DD    DDN    EV 
Sbjct: 244 ENSEQANTQDSGGSQLLE-----------HPSRKIFRKSRISEEDDRSELDDNNTMEEVK 292

Query: 140 DDNSDDSEAPD--------DNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDD 191
            D++++S + D        D+  DS+  +D+ ++    +  + D  + + + + +    +
Sbjct: 293 SDSTENSNSRDTGLSQPRRDSKGDSQ--EDSKENLSQEESQNVDGPSSESSQEANLSSQE 350

Query: 192 NSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDD 251
           NS +S ++   +S  DN D +    +  +DSD  ++  D S     S  +S      S+ 
Sbjct: 351 NSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEE--DSSHTLSHSKSESREEQADSES 408

Query: 252 SEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDD 311
           SE+ + S +  E+P+D  ++S + +     S +++  S++S + +D SD  ++   K D 
Sbjct: 409 SESLNFSEESPESPED--ENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDS 466

Query: 312 SDVPEDKSDDSD 323
           +      S + D
Sbjct: 467 NSTESKSSSEED 478



 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 60/262 (22%), Positives = 113/262 (43%), Gaps = 28/262 (10%)

Query: 118 EPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNS------------DD 165
           +P  + S+  N   N   ++  +   +  +A   +S  S+  +  S            DD
Sbjct: 219 DPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDD 278

Query: 166 SEAPDDNSDDSEAPDDNSDDSDVPD--------DNSDDSSDDNSDDSSDDNSDDSDVPDD 217
               DDN+   E   D++++S+  D        D+  DS +D+ ++ S + S + D P  
Sbjct: 279 RSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSS 338

Query: 218 KSDD----SDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSE 273
           +S      S   + S    +V  +S  D+  P  S  + +   DSS++  +   S   SE
Sbjct: 339 ESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSE 398

Query: 274 APDDSSDDSEASDDSSDDSEASDDSSDD--SEAPDDKSDDSDVPEDKSDDSDVPDDNSDD 331
           + ++ +D    S +S + SE S +S +D  S + +     S   E +S++S   +D+SD 
Sbjct: 399 SREEQADSE--SSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDS 456

Query: 332 LEVPVPAEDLCNEGQIASDEEE 353
            +     ED  +    +S EE+
Sbjct: 457 QDSSRSKEDSNSTESKSSSEED 478



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 79/378 (20%), Positives = 155/378 (41%), Gaps = 42/378 (11%)

Query: 126 DDNDDDNGNDLEVPDDNSDDSEAPDDN--SDDSEAPDDNSDDSEAPDD-NSDDSEAPDDN 182
           +D+++  G+  + P    + SE+ + +  S + +A +D SD +++ +   SDD +     
Sbjct: 28  EDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRL 87

Query: 183 SDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDV---PDDKSDDSDVPDDSSDDSDVPDDSS 239
           +           D  DD+ DDS DD   D D    P D+ +  +    S +DSD    +S
Sbjct: 88  AGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQAS 147

Query: 240 DDSEAP--DDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDD 297
           ++S AP   DS+ D+ +     D+    +D  D      DS+ +SE+ +         + 
Sbjct: 148 EES-APQGQDSAQDTTSESRELDN----EDRVDSKPEGGDSTQESESEEHWVGGGSDGES 202

Query: 298 SSDDSEAPDDKSDDSDVPE----------------------DKSDDSDVPDDNSDDLEVP 335
           S  D    DD+   SD PE                      + S+ ++  D     L + 
Sbjct: 203 SHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQL-LE 261

Query: 336 VPAEDLCNEGQIA--SDEEELVEAAAAVS-QHDSSDDAGEQDLGENLSKPPSDPEANPEV 392
            P+  +  + +I+   D  EL +       + DS++++  +D G  LS+P  D + + + 
Sbjct: 262 HPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTG--LSQPRRDSKGDSQE 319

Query: 393 SERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPL 452
             ++  ++EE +  V+      S+   +       +++ + + E        T + VE  
Sbjct: 320 DSKENLSQEE-SQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQ 378

Query: 453 RKRKAKTKNVSVTPGHKK 470
               +  ++ S T  H K
Sbjct: 379 EDSDSSEEDSSHTLSHSK 396



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 74/332 (22%), Positives = 134/332 (40%), Gaps = 42/332 (12%)

Query: 125 DDDNDD--DNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDS-EAPDDNSDDSE--AP 179
           DD +DD  D+G+D    DD+    +   +  +     D++SDD+ +A ++++   +  A 
Sbjct: 100 DDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQ 159

Query: 180 DDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDD------SDVPDDKSDDSDVPDD--SSDD 231
           D  S+  ++ +++  DS  +  D + +  S++      SD      D S++ D+   SDD
Sbjct: 160 DTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDD 219

Query: 232 SDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPD---------DSSDDS 282
            +       +S          E+ ++S   +      S   E P             DD 
Sbjct: 220 PESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDR 279

Query: 283 EASDDSSDDSEASDDSSDDSEAPDD--KSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAED 340
              DD++   E   DS+++S + D        D   D  +DS       +   V  P+ +
Sbjct: 280 SELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSE 339

Query: 341 LCNEGQIASDE--EELVEAAAAVSQHDSSD------------DAGEQDLGENLSKPPS-- 384
              E  ++S E   E  E   + S+ D+ D            D+ E+D    LS   S  
Sbjct: 340 SSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSES 399

Query: 385 -DPEANPEVSERKLPTEEEP-APVVEQSGKRK 414
            + +A+ E SE    +EE P +P  E S  ++
Sbjct: 400 REEQADSESSESLNFSEESPESPEDENSSSQE 431



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 86/411 (20%), Positives = 159/411 (38%), Gaps = 40/411 (9%)

Query: 13  EPEEDEDCYILNVQSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQ 72
           + ++DED        S DDT G   +   PK +        SR G    S    +A +  
Sbjct: 101 DKDDDED-------DSGDDTFGDDDSGPGPKDRQE---GGNSRLGSDEDSDDTIQASEES 150

Query: 73  ASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDN 132
           A        DS ++  +   +      ++S  E  +      + +      SD ++   +
Sbjct: 151 APQ----GQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGD 206

Query: 133 GNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDN 192
           G++L+     SDD E+      +S     NS   ++ +   +  +A   +S  S + +  
Sbjct: 207 GSELDDEGMQSDDPESIRSERGNSRM---NSAGMKSKESGENSEQANTQDSGGSQLLEHP 263

Query: 193 SDD----SSDDNSDDSS--DDNSDDSDVPDDKSDDSDVPDD--SSDDSDVPDDSSDDSEA 244
           S      S     DD S  DDN+   +V  D +++S+  D   S    D   DS +DS+ 
Sbjct: 264 SRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKE 323

Query: 245 PDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEAS-DDSSDDSE 303
                +       SS+ S+  + SS ++ +       SE+  D+ D + +  +D  D   
Sbjct: 324 NLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDS 383

Query: 304 APDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQ 363
           + +D S      + +S +     ++S+ L     + +   +   +S E     +++A SQ
Sbjct: 384 SEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQ 443

Query: 364 ----HDSSDDAGEQDLGENL-------SKPPSDPEA---NPEVSERKLPTE 400
               H   DD+  QD   +        SK  S+ +    N E+  RKL  +
Sbjct: 444 SEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVD 494



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 73/392 (18%), Positives = 149/392 (38%), Gaps = 81/392 (20%)

Query: 126 DDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDS-EAPDDNSDDSE--APDDN 182
           DD++DD+G+D    DD+    +   +  +     D++SDD+ +A ++++   +  A D  
Sbjct: 103 DDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTT 162

Query: 183 SDDSDVPDDNSDDSSDDNSDDSSDDNSD---------------DSDVPDDKSDDSDVPD- 226
           S+  ++ +++  DS  +  D + +  S+               D    DD+   SD P+ 
Sbjct: 163 SESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPES 222

Query: 227 ---------------------DSSDDSDVPDDSS--------------------DDSEAP 245
                                ++S+ ++  D                       DD    
Sbjct: 223 IRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSEL 282

Query: 246 DDSSDDSEAPDDSSDDSEAPD------------DSSDDSEAPDDSSDDSEASDDSSDDSE 293
           DD++   E   DS+++S + D            DS +DS+      +       SS+ S+
Sbjct: 283 DDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQ 342

Query: 294 ASDDSSDD--SEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDE 351
            ++ SS +  SE+ ++   +S         S V D    D      +  L +    + +E
Sbjct: 343 EANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREE 402

Query: 352 EELVEAAAAVSQHDSSDDAGEQDLG---ENLSKPPSDPEANPEVSERKLPTEEEPAPVVE 408
           +   E++ +++  + S ++ E +     E L    S  E+  E S     +EE+ +   +
Sbjct: 403 QADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESH----SEEDDSDSQD 458

Query: 409 QSGKRKSKTKTIVEPPRKRQTKTKNIVEPPRK 440
            S  ++    T  +   +   + KNI    RK
Sbjct: 459 SSRSKEDSNSTESKSSSEEDGQLKNIEIESRK 490



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 50/242 (20%), Positives = 99/242 (40%), Gaps = 25/242 (10%)

Query: 15  EEDEDCYILNVQSSSDDTSGS-SVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQA 73
           E D++  +  V+S S + S S       P+R +       S+   +   S     P  ++
Sbjct: 281 ELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSES 340

Query: 74  SSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNG 133
           S    + S  +      E ++  + E   D+  P   +V+   QE       D +++D+ 
Sbjct: 341 SQEANLSSQENSS----ESQEEVVSESRGDNPDPTTSYVED--QE-----DSDSSEEDSS 389

Query: 134 NDLEVPDDNSDDSEAPDDNSDD----SEAP----DDNSDDSEAPDDNSDDSEAPDDNS-- 183
           + L      S + +A  ++S+      E+P    D+NS   E    +S  +E+  + S  
Sbjct: 390 HTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHS 449

Query: 184 --DDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDD 241
             DDSD   D+S    D NS +S   + +D  + + + +   +  D+  +  + D   +D
Sbjct: 450 EEDDSD-SQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYHNKPIGDQDDND 508

Query: 242 SE 243
            +
Sbjct: 509 CQ 510



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 33/140 (23%), Positives = 55/140 (39%), Gaps = 14/140 (10%)

Query: 80  DSDSDEE--CHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLE 137
           DSDS EE   HT    K++  E  +D ES E  +      E P        +D+N +  E
Sbjct: 380 DSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESP--------EDENSSSQE 431

Query: 138 VPDDNSDDSEAPDDNS----DDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNS 193
               +S  +E+  + S    DDS++ D +    ++    S  S   D    + ++     
Sbjct: 432 GLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKL 491

Query: 194 DDSSDDNSDDSSDDNSDDSD 213
              +  N      D++D  D
Sbjct: 492 TVDAYHNKPIGDQDDNDCQD 511


>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
           precursor [Homo sapiens]
          Length = 497

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 54/252 (21%), Positives = 113/252 (44%), Gaps = 27/252 (10%)

Query: 82  DSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDND--DDNGNDLEVP 139
           ++ E+ +T +   ++LLE           H    I     +  +DD    DDN    EV 
Sbjct: 228 ENSEQANTQDSGGSQLLE-----------HPSRKIFRKSRISEEDDRSELDDNNTMEEVK 276

Query: 140 DDNSDDSEAPD--------DNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDD 191
            D++++S + D        D+  DS+  +D+ ++    +  + D  + + + + +    +
Sbjct: 277 SDSTENSNSRDTGLSQPRRDSKGDSQ--EDSKENLSQEESQNVDGPSSESSQEANLSSQE 334

Query: 192 NSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDD 251
           NS +S ++   +S  DN D +    +  +DSD  ++  D S     S  +S      S+ 
Sbjct: 335 NSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEE--DSSHTLSHSKSESREEQADSES 392

Query: 252 SEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDD 311
           SE+ + S +  E+P+D  ++S + +     S +++  S++S + +D SD  ++   K D 
Sbjct: 393 SESLNFSEESPESPED--ENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDS 450

Query: 312 SDVPEDKSDDSD 323
           +      S + D
Sbjct: 451 NSTESKSSSEED 462



 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 60/262 (22%), Positives = 113/262 (43%), Gaps = 28/262 (10%)

Query: 118 EPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNS------------DD 165
           +P  + S+  N   N   ++  +   +  +A   +S  S+  +  S            DD
Sbjct: 203 DPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDD 262

Query: 166 SEAPDDNSDDSEAPDDNSDDSDVPD--------DNSDDSSDDNSDDSSDDNSDDSDVPDD 217
               DDN+   E   D++++S+  D        D+  DS +D+ ++ S + S + D P  
Sbjct: 263 RSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSS 322

Query: 218 KSDD----SDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSE 273
           +S      S   + S    +V  +S  D+  P  S  + +   DSS++  +   S   SE
Sbjct: 323 ESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSE 382

Query: 274 APDDSSDDSEASDDSSDDSEASDDSSDD--SEAPDDKSDDSDVPEDKSDDSDVPDDNSDD 331
           + ++ +D    S +S + SE S +S +D  S + +     S   E +S++S   +D+SD 
Sbjct: 383 SREEQADSE--SSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDS 440

Query: 332 LEVPVPAEDLCNEGQIASDEEE 353
            +     ED  +    +S EE+
Sbjct: 441 QDSSRSKEDSNSTESKSSSEED 462



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 74/332 (22%), Positives = 134/332 (40%), Gaps = 42/332 (12%)

Query: 125 DDDNDD--DNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDS-EAPDDNSDDSE--AP 179
           DD +DD  D+G+D    DD+    +   +  +     D++SDD+ +A ++++   +  A 
Sbjct: 84  DDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQ 143

Query: 180 DDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDD------SDVPDDKSDDSDVPDD--SSDD 231
           D  S+  ++ +++  DS  +  D + +  S++      SD      D S++ D+   SDD
Sbjct: 144 DTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDD 203

Query: 232 SDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPD---------DSSDDS 282
            +       +S          E+ ++S   +      S   E P             DD 
Sbjct: 204 PESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDR 263

Query: 283 EASDDSSDDSEASDDSSDDSEAPDD--KSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAED 340
              DD++   E   DS+++S + D        D   D  +DS       +   V  P+ +
Sbjct: 264 SELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSE 323

Query: 341 LCNEGQIASDE--EELVEAAAAVSQHDSSD------------DAGEQDLGENLSKPPS-- 384
              E  ++S E   E  E   + S+ D+ D            D+ E+D    LS   S  
Sbjct: 324 SSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSES 383

Query: 385 -DPEANPEVSERKLPTEEEP-APVVEQSGKRK 414
            + +A+ E SE    +EE P +P  E S  ++
Sbjct: 384 REEQADSESSESLNFSEESPESPEDENSSSQE 415



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 68/298 (22%), Positives = 117/298 (39%), Gaps = 22/298 (7%)

Query: 126 DDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDD 185
           DD DDD        +D+S D    DD  D    P D  +   +   + +DS   DD    
Sbjct: 84  DDKDDD--------EDDSGDDTFGDD--DSGPGPKDRQEGGNSRLGSDEDS---DDTIQA 130

Query: 186 SDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDS-SDDSDVPDDSSDDSEA 244
           S+       DS+ D + +S +   D+ D  D K +  D   +S S++  V   S  +S  
Sbjct: 131 SEESAPQGQDSAQDTTSESRE--LDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSH 188

Query: 245 PDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEA 304
            D S  D E     SDD E+      +S          E+ ++S   +      S   E 
Sbjct: 189 GDGSELDDEGM--QSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEH 246

Query: 305 PDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQH 364
           P  K        ++ D S++ D+N+ +    V ++   N     +   +    +   SQ 
Sbjct: 247 PSRKIFRKSRISEEDDRSELDDNNTME---EVKSDSTENSNSRDTGLSQPRRDSKGDSQE 303

Query: 365 DSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVE 422
           DS ++  +++  +N+  P S+      +S ++  +E +   V E  G     T + VE
Sbjct: 304 DSKENLSQEE-SQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVE 360



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 86/411 (20%), Positives = 159/411 (38%), Gaps = 40/411 (9%)

Query: 13  EPEEDEDCYILNVQSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQ 72
           + ++DED        S DDT G   +   PK +        SR G    S    +A +  
Sbjct: 85  DKDDDED-------DSGDDTFGDDDSGPGPKDRQE---GGNSRLGSDEDSDDTIQASEES 134

Query: 73  ASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDN 132
           A        DS ++  +   +      ++S  E  +      + +      SD ++   +
Sbjct: 135 APQ----GQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGD 190

Query: 133 GNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDN 192
           G++L+     SDD E+      +S     NS   ++ +   +  +A   +S  S + +  
Sbjct: 191 GSELDDEGMQSDDPESIRSERGNSRM---NSAGMKSKESGENSEQANTQDSGGSQLLEHP 247

Query: 193 SDD----SSDDNSDDSS--DDNSDDSDVPDDKSDDSDVPDD--SSDDSDVPDDSSDDSEA 244
           S      S     DD S  DDN+   +V  D +++S+  D   S    D   DS +DS+ 
Sbjct: 248 SRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKE 307

Query: 245 PDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEAS-DDSSDDSE 303
                +       SS+ S+  + SS ++ +       SE+  D+ D + +  +D  D   
Sbjct: 308 NLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDS 367

Query: 304 APDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQ 363
           + +D S      + +S +     ++S+ L     + +   +   +S E     +++A SQ
Sbjct: 368 SEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQ 427

Query: 364 ----HDSSDDAGEQDLGENL-------SKPPSDPEA---NPEVSERKLPTE 400
               H   DD+  QD   +        SK  S+ +    N E+  RKL  +
Sbjct: 428 SEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVD 478



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 77/366 (21%), Positives = 146/366 (39%), Gaps = 44/366 (12%)

Query: 140 DDNSDDSEAPDDNSDDSEAP----DDNSDDSEAPDD-NSDDSEAPDDNSDDSDVPDDNSD 194
           ++ S+DSE    +   +  P    +D SD +++ +   SDD +     +           
Sbjct: 24  NNESEDSEEWKGHLAQAPTPPLANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGG 83

Query: 195 DSSDDNSDDSSDDNSDDSDV---PDDKSDDSDVPDDSSDDSDVPDDSSDDSEAP--DDSS 249
           D  DD+ DDS DD   D D    P D+ +  +    S +DSD    +S++S AP   DS+
Sbjct: 84  DDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEES-APQGQDSA 142

Query: 250 DDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKS 309
            D+ +     D+    +D  D      DS+ +SE+ +         + S  D    DD+ 
Sbjct: 143 QDTTSESRELDN----EDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEG 198

Query: 310 DDSDVPE----------------------DKSDDSDVPDDNSDDLEVPVPAEDLCNEGQI 347
             SD PE                      + S+ ++  D     L +  P+  +  + +I
Sbjct: 199 MQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQL-LEHPSRKIFRKSRI 257

Query: 348 A--SDEEELVEAAAAVS-QHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPA 404
           +   D  EL +       + DS++++  +D G  LS+P  D + + +   ++  ++EE +
Sbjct: 258 SEEDDRSELDDNNTMEEVKSDSTENSNSRDTG--LSQPRRDSKGDSQEDSKENLSQEE-S 314

Query: 405 PVVEQSGKRKSKTKTIVEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRKAKTKNVSV 464
             V+      S+   +       +++ + + E        T + VE      +  ++ S 
Sbjct: 315 QNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSH 374

Query: 465 TPGHKK 470
           T  H K
Sbjct: 375 TLSHSK 380



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 73/392 (18%), Positives = 149/392 (38%), Gaps = 81/392 (20%)

Query: 126 DDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDS-EAPDDNSDDSE--APDDN 182
           DD++DD+G+D    DD+    +   +  +     D++SDD+ +A ++++   +  A D  
Sbjct: 87  DDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTT 146

Query: 183 SDDSDVPDDNSDDSSDDNSDDSSDDNSD---------------DSDVPDDKSDDSDVPD- 226
           S+  ++ +++  DS  +  D + +  S+               D    DD+   SD P+ 
Sbjct: 147 SESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPES 206

Query: 227 ---------------------DSSDDSDVPDDSS--------------------DDSEAP 245
                                ++S+ ++  D                       DD    
Sbjct: 207 IRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSEL 266

Query: 246 DDSSDDSEAPDDSSDDSEAPD------------DSSDDSEAPDDSSDDSEASDDSSDDSE 293
           DD++   E   DS+++S + D            DS +DS+      +       SS+ S+
Sbjct: 267 DDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQ 326

Query: 294 ASDDSSDD--SEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDE 351
            ++ SS +  SE+ ++   +S         S V D    D      +  L +    + +E
Sbjct: 327 EANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREE 386

Query: 352 EELVEAAAAVSQHDSSDDAGEQDLG---ENLSKPPSDPEANPEVSERKLPTEEEPAPVVE 408
           +   E++ +++  + S ++ E +     E L    S  E+  E S     +EE+ +   +
Sbjct: 387 QADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESH----SEEDDSDSQD 442

Query: 409 QSGKRKSKTKTIVEPPRKRQTKTKNIVEPPRK 440
            S  ++    T  +   +   + KNI    RK
Sbjct: 443 SSRSKEDSNSTESKSSSEEDGQLKNIEIESRK 474



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 50/242 (20%), Positives = 99/242 (40%), Gaps = 25/242 (10%)

Query: 15  EEDEDCYILNVQSSSDDTSGS-SVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQA 73
           E D++  +  V+S S + S S       P+R +       S+   +   S     P  ++
Sbjct: 265 ELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSES 324

Query: 74  SSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNG 133
           S    + S  +      E ++  + E   D+  P   +V+   QE       D +++D+ 
Sbjct: 325 SQEANLSSQENSS----ESQEEVVSESRGDNPDPTTSYVED--QE-----DSDSSEEDSS 373

Query: 134 NDLEVPDDNSDDSEAPDDNSDD----SEAP----DDNSDDSEAPDDNSDDSEAPDDNS-- 183
           + L      S + +A  ++S+      E+P    D+NS   E    +S  +E+  + S  
Sbjct: 374 HTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHS 433

Query: 184 --DDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDD 241
             DDSD   D+S    D NS +S   + +D  + + + +   +  D+  +  + D   +D
Sbjct: 434 EEDDSD-SQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYHNKPIGDQDDND 492

Query: 242 SE 243
            +
Sbjct: 493 CQ 494



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 33/140 (23%), Positives = 55/140 (39%), Gaps = 14/140 (10%)

Query: 80  DSDSDEE--CHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLE 137
           DSDS EE   HT    K++  E  +D ES E  +      E P        +D+N +  E
Sbjct: 364 DSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESP--------EDENSSSQE 415

Query: 138 VPDDNSDDSEAPDDNS----DDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNS 193
               +S  +E+  + S    DDS++ D +    ++    S  S   D    + ++     
Sbjct: 416 GLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKL 475

Query: 194 DDSSDDNSDDSSDDNSDDSD 213
              +  N      D++D  D
Sbjct: 476 TVDAYHNKPIGDQDDNDCQD 495


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 73.9 bits (180), Expect = 5e-13
 Identities = 47/198 (23%), Positives = 89/198 (44%), Gaps = 8/198 (4%)

Query: 132 NGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDD 191
           NG + +  D    D E  DD+ +D E  +D  +D +  +  +  + A    S+D D  DD
Sbjct: 136 NGKNAKKEDS---DEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDD 192

Query: 192 NSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDD 251
             D+  DD+ +D S++ + ++     K     VP  + + ++  D+  DD +  DD  +D
Sbjct: 193 EDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDED 252

Query: 252 SEAPDDSSDDSEAPDDSSDD-SEAP----DDSSDDSEASDDSSDDSEASDDSSDDSEAPD 306
            E  DD  D+ E  ++  +   EAP     + +    A +      E ++ ++  +    
Sbjct: 253 DEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVG 312

Query: 307 DKSDDSDVPEDKSDDSDV 324
           + + +   PE K+  SDV
Sbjct: 313 NLNFNKSAPELKTGISDV 330



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 45/197 (22%), Positives = 89/197 (45%), Gaps = 17/197 (8%)

Query: 124 SDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 183
           SD++ DDD+       +++ +D E  D++ D+ E     +  +    ++ DD +  DD  
Sbjct: 145 SDEEEDDDS-------EEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDED 197

Query: 184 DDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSE 243
           DD    DD  DDS ++  + +       + V   K+ +    +D  +D +  DD  D+ +
Sbjct: 198 DD----DDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDD 253

Query: 244 APDDSSDDSEAPDDSSDD--SEAP----DDSSDDSEAPDDSSDDSEASDDSSDDSEASDD 297
             DD  DD E  ++  ++   EAP     + +    AP+      E ++ ++  +    +
Sbjct: 254 EDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGN 313

Query: 298 SSDDSEAPDDKSDDSDV 314
            + +  AP+ K+  SDV
Sbjct: 314 LNFNKSAPELKTGISDV 330



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 31/143 (21%), Positives = 65/143 (45%)

Query: 138 VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSS 197
           +P   + + +       D E  DD+ +D E  +D  +D +  +  +  +      S+D  
Sbjct: 129 IPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDED 188

Query: 198 DDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDD 257
           D++ +D  DD+ D+ D  ++++ ++           VP  + + +E  D+  DD +  DD
Sbjct: 189 DEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDD 248

Query: 258 SSDDSEAPDDSSDDSEAPDDSSD 280
             +D E  DD  D+ E  ++  +
Sbjct: 249 DDEDDEDDDDEDDEEEEEEEEEE 271



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 41/160 (25%), Positives = 72/160 (45%), Gaps = 20/160 (12%)

Query: 188 VPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDD 247
           +P   + +  +   +DS ++  DDS+  +D+ DD D  +D  +D   P      + AP  
Sbjct: 129 IPAKGAKNGKNAKKEDSDEEEDDDSE--EDEEDDED--EDEDEDEIEPAAMKAAAAAPAS 184

Query: 248 SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDS-------EASDDSSD 300
             +D E      DD    DD  DD +  DDS +++  +  +           +A + + D
Sbjct: 185 EDEDDE------DDE---DDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAED 235

Query: 301 DSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAED 340
           + E  DD+ +D D  ED  DD D  D+  ++ E   P ++
Sbjct: 236 EDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKE 275



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 49/196 (25%), Positives = 83/196 (42%), Gaps = 29/196 (14%)

Query: 234 VPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSE 293
           +P   + + +       D E  DDS +D E  +D  +D +  + ++  + A+  +S+D  
Sbjct: 129 IPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASED-- 186

Query: 294 ASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEE 353
             +D  DD +  DD  D+ D  E+++ ++           VPV A+++  +     D+E+
Sbjct: 187 --EDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDED 244

Query: 354 LVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKR 413
                      D  DD  ++D          D E + E  E     EEE  PV E  GKR
Sbjct: 245 ----------EDDDDDEDDED---------DDDEDDEEEEE-----EEEEEPVKEAPGKR 280

Query: 414 KSK-TKTIVEPPRKRQ 428
           K +  K    P  K+Q
Sbjct: 281 KKEMAKQKAAPEAKKQ 296



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 36/136 (26%), Positives = 67/136 (49%), Gaps = 7/136 (5%)

Query: 80  DSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVP 139
           DSD +E+  + E+++    E   +DE  E   +K A   P    S+D++D+D+ +D +  
Sbjct: 144 DSDEEEDDDSEEDEEDDEDEDEDEDEI-EPAAMKAAAAAPA---SEDEDDEDDEDDEDDD 199

Query: 140 DDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDD 199
           DD  DDSE   + + ++            P    + +E  D+  DD D  DD+ +D  DD
Sbjct: 200 DDEEDDSE---EEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDD 256

Query: 200 NSDDSSDDNSDDSDVP 215
           + +D  ++  ++ + P
Sbjct: 257 DDEDDEEEEEEEEEEP 272


>gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 3859

 Score = 73.6 bits (179), Expect = 6e-13
 Identities = 64/227 (28%), Positives = 98/227 (43%), Gaps = 15/227 (6%)

Query: 104  DESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNS 163
            D  P+C  V     + P+V+      D + + + VP    DDS A    +D+   PD  +
Sbjct: 3646 DPWPDCPVVPVTRTDGPVVL------DSSADGVVVPVTPGDDSVALVTPTDNLVVPDLTT 3699

Query: 164  DDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSD 223
            D    PD ++D        +DD  VP+    D+   NS       +D+    D  +D   
Sbjct: 3700 DGPVVPDPSADGPVVLVSLADDLLVPNPPVKDTVVPNSV------ADNPVALDPVTDCPL 3753

Query: 224  VPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSE 283
            VP+ S++   V D   +    PD S+DD    +  ++    PD S++    PD  +D S+
Sbjct: 3754 VPEPSANGLVVTDSLDEGPVVPDPSADDPVVLNPETNGLVVPDISANGPVVPDTPTDGSD 3813

Query: 284  ASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSD 330
            A+    D SE    ++D    PD  SD   VPE   DD  VP  + D
Sbjct: 3814 ATVTPDDCSEVFVTATD---GPDVVSDCPIVPETSDDDLIVPGISDD 3857



 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 69/270 (25%), Positives = 110/270 (40%), Gaps = 15/270 (5%)

Query: 104  DESPECCHVKPAIQEPPIVISD---DDNDDDNGNDLE--VPDDNSDDSEAPDDNSDDSEA 158
            D +P+C  V P +     V+ D   D     N  D+   VPD  +D    PD   D    
Sbjct: 3589 DSAPDC-PVVPVLPTDGFVVLDLLVDGVVVPNPADVGPVVPDPTTD---GPDSIKDFPLV 3644

Query: 159  PDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDK 218
            PD   D    P   +D     D ++D   VP    DDS       +    +D+  VPD  
Sbjct: 3645 PDPWPDCPVVPVTRTDGPVVLDSSADGVVVPVTPGDDSV------ALVTPTDNLVVPDLT 3698

Query: 219  SDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDS 278
            +D   VPD S+D   V    +DD   P+    D+  P+  +D+  A D  +D    P+ S
Sbjct: 3699 TDGPVVPDPSADGPVVLVSLADDLLVPNPPVKDTVVPNSVADNPVALDPVTDCPLVPEPS 3758

Query: 279  SDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPA 338
            ++    +D   +     D S+DD    + +++   VP+  ++   VPD  +D  +  V  
Sbjct: 3759 ANGLVVTDSLDEGPVVPDPSADDPVVLNPETNGLVVPDISANGPVVPDTPTDGSDATVTP 3818

Query: 339  EDLCNEGQIASDEEELVEAAAAVSQHDSSD 368
            +D       A+D  ++V     V +    D
Sbjct: 3819 DDCSEVFVTATDGPDVVSDCPIVPETSDDD 3848



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 66/233 (28%), Positives = 91/233 (39%), Gaps = 30/233 (12%)

Query: 134  NDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDD-------- 185
            ND  VPD  +D +       DD  APD   +        +D    PD  +D         
Sbjct: 3132 NDSVVPDFTADWTVVSVSPPDDLVAPDPPDEVPVVLVPITDGPVVPDLTTDGLVVSVTPA 3191

Query: 186  ---------SDVPD-----DNSDDSSDDNSDDS--SDDNSDDSDVPDDKSDDSDVPDDSS 229
                     +D PD      +S    D +SD    +D   DD  VP   +DDS VPD  +
Sbjct: 3192 GAPVVPVFLTDCPDVTVTPADSPVVPDPSSDGPVVADSLDDDGLVPVTPADDSVVPDSPA 3251

Query: 230  DDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPD---DSSDDSEASD 286
            +   VPD ++D   APD S D    P   +D   AP  S   ++ PD      D    SD
Sbjct: 3252 NGLVVPDPTTDGPVAPDPSVDGPVVPVTPAD---APTVSVTLADCPDVTVTPPDGLVVSD 3308

Query: 287  DSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAE 339
                    +  S++D       +D SDV    +D  DVP   ++  +VPV  E
Sbjct: 3309 SKRGGPVVTGLSTNDPVITATPADFSDVTVTPADFEDVPVTPANCPDVPVNPE 3361



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 65/241 (26%), Positives = 94/241 (39%), Gaps = 12/241 (4%)

Query: 106  SPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDD 165
            +P  C   P   E P+V       D   + L VP   SDD    +        PD  S+ 
Sbjct: 3349 TPANCPDVPVNPESPVV------SDLAVDFLVVPVVPSDDLVVLEPPDKVPVVPDPISNG 3402

Query: 166  SEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDD----NSDDSSDDNSDDSDVPDDK--S 219
                D  ++++ A D + D S VP   +D         +  D +   +DDS V D K  +
Sbjct: 3403 LVVSDPITNNTAATDPSVDGSVVPVSPADGPVAPVTLADCPDVTITPADDSVVSDSKIRA 3462

Query: 220  DDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSS 279
            +  DVP   +D  +VP +        D + D    P    DD  AP+   +    PD  +
Sbjct: 3463 EFEDVPVTIADCPNVPVNPKSGPVVSDLAVDCPVVPIPPPDDLVAPEPPDEVPVVPDPIT 3522

Query: 280  DDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAE 339
            D    SD  +D   ASD S D    P        V +  +D S +PD ++D    PV   
Sbjct: 3523 DSLVVSDPMTDGPVASDPSIDGIVVPVVSPSGLLVLDSVADVSILPDTSADVPVTPVTLA 3582

Query: 340  D 340
            D
Sbjct: 3583 D 3583



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 70/274 (25%), Positives = 99/274 (36%), Gaps = 18/274 (6%)

Query: 130  DDNGNDLEVPDDNSDDSEAPDDNSDD--SEAPDDNSDDSEAPDDNSD-------DSEAPD 180
            D     L V +   DD    + ++    S  P D +D    P D  D       DS  PD
Sbjct: 3079 DPTAEGLVVSNPTVDDPVVTNPSTKGLVSATPADCADVPVIPADCPDVLVNLVNDSVVPD 3138

Query: 181  DNSDDSDV----PDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPD 236
              +D + V    PDD       D         +D   VPD  +D   V    +    VP 
Sbjct: 3139 FTADWTVVSVSPPDDLVAPDPPDEVPVVLVPITDGPVVPDLTTDGLVVSVTPAGAPVVPV 3198

Query: 237  DSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASD 296
              +D  +     +D    PD SSD     D   DD   P   +DDS   D  ++     D
Sbjct: 3199 FLTDCPDVTVTPADSPVVPDPSSDGPVVADSLDDDGLVPVTPADDSVVPDSPANGLVVPD 3258

Query: 297  DSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVE 356
             ++D   APD   D   VP   +D   V    +D  +V V   D    G + SD +    
Sbjct: 3259 PTTDGPVAPDPSVDGPVVPVTPADAPTVSVTLADCPDVTVTPPD----GLVVSDSKRGGP 3314

Query: 357  AAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANP 390
                +S +D    A   D  + ++  P+D E  P
Sbjct: 3315 VVTGLSTNDPVITATPADFSD-VTVTPADFEDVP 3347



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 83/357 (23%), Positives = 119/357 (33%), Gaps = 53/357 (14%)

Query: 102  SDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDSEA-PDDNSDDSEAPD 160
            +DD       ++   ++ P+ I+D  N   N     V  D + D    P    DD  AP+
Sbjct: 3450 ADDSVVSDSKIRAEFEDVPVTIADCPNVPVNPKSGPVVSDLAVDCPVVPIPPPDDLVAPE 3509

Query: 161  DNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSS----DDNSDDSDVPD 216
               +    PD  +D     D  +D     D + D         S     D  +D S +PD
Sbjct: 3510 PPDEVPVVPDPITDSLVVSDPMTDGPVASDPSIDGIVVPVVSPSGLLVLDSVADVSILPD 3569

Query: 217  DKSDDSDVPDDSSDDSDVPDDSSD------------------------------------ 240
              +D    P   +D S VPD + D                                    
Sbjct: 3570 TSADVPVTPVTLADGSVVPDSAPDCPVVPVLPTDGFVVLDLLVDGVVVPNPADVGPVVPD 3629

Query: 241  -DSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSS 299
              ++ PD   D    PD   D    P   +D     D S+D         DDS A    +
Sbjct: 3630 PTTDGPDSIKDFPLVPDPWPDCPVVPVTRTDGPVVLDSSADGVVVPVTPGDDSVALVTPT 3689

Query: 300  DDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVP-VPAEDLCNEGQIASDEEEL--VE 356
            D+   PD  +D   VP+  +D   V    +DDL VP  P +D      +A +   L  V 
Sbjct: 3690 DNLVVPDLTTDGPVVPDPSADGPVVLVSLADDLLVPNPPVKDTVVPNSVADNPVALDPVT 3749

Query: 357  AAAAVSQHDSSDDAGEQDLGENLSKPPSDPEA------NPEVSERKLPTEEEPAPVV 407
                V +  ++       L E    P  DP A      NPE +   +P      PVV
Sbjct: 3750 DCPLVPEPSANGLVVTDSLDEGPVVP--DPSADDPVVLNPETNGLVVPDISANGPVV 3804



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 60/244 (24%), Positives = 89/244 (36%), Gaps = 9/244 (3%)

Query: 106  SPECCHVKPAIQEP----PIVISDDDNDDDNGNDLEV-PDDNSDDSEAPDDNSDDSEAPD 160
            +P  C V P         P+  +D   D     D  V P   +DD   P   +D      
Sbjct: 912  TPTDCPVAPVTSADCPVVPVTPADSPADPVTAADGPVVPFTPADDPIVPVTPADSPVVSV 971

Query: 161  DNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSD----DNSDDSDVPD 216
              +D    P  ++D    P   +DD  V    ++  +   +   S      ++D    P 
Sbjct: 972  TPADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVSPV 1031

Query: 217  DKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPD 276
              +D   VP  ++ D  VP   +D   +P  S+D    P  S+D    P    D    P 
Sbjct: 1032 TTADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPV 1091

Query: 277  DSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPV 336
             S+D   A   S+D       S+D   AP   +D   VP   +D   +P   +DD  VPV
Sbjct: 1092 TSADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDPIVPV 1151

Query: 337  PAED 340
               D
Sbjct: 1152 TPAD 1155



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 70/268 (26%), Positives = 96/268 (35%), Gaps = 27/268 (10%)

Query: 99   EINSDDESPECCHVKPAIQEPPIVISDD-------DN----DDDNGNDLEVPDDNSDDSE 147
            ++  + ESP    +       P+V SDD       D      D   N L V D  ++++ 
Sbjct: 3355 DVPVNPESPVVSDLAVDFLVVPVVPSDDLVVLEPPDKVPVVPDPISNGLVVSDPITNNTA 3414

Query: 148  APDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDD-------- 199
            A D + D S  P   +D   AP   +D  +     +DDS V D       +D        
Sbjct: 3415 ATDPSVDGSVVPVSPADGPVAPVTLADCPDVTITPADDSVVSDSKIRAEFEDVPVTIADC 3474

Query: 200  --------NSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDD 251
                    +    SD   D   VP    DD   P+   +   VPD  +D     D  +D 
Sbjct: 3475 PNVPVNPKSGPVVSDLAVDCPVVPIPPPDDLVAPEPPDEVPVVPDPITDSLVVSDPMTDG 3534

Query: 252  SEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDD 311
              A D S D    P  S       D  +D S   D S+D        +D S  PD   D 
Sbjct: 3535 PVASDPSIDGIVVPVVSPSGLLVLDSVADVSILPDTSADVPVTPVTLADGSVVPDSAPDC 3594

Query: 312  SDVPEDKSDDSDVPDDNSDDLEVPVPAE 339
              VP   +D   V D   D + VP PA+
Sbjct: 3595 PVVPVLPTDGFVVLDLLVDGVVVPNPAD 3622



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 68/267 (25%), Positives = 96/267 (35%), Gaps = 46/267 (17%)

Query: 120  PIVISDDDNDDDN-GNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSD-------------- 164
            P+  +DD    D+  N L VPD  +D   APD + D    P   +D              
Sbjct: 3237 PVTPADDSVVPDSPANGLVVPDPTTDGPVAPDPSVDGPVVPVTPADAPTVSVTLADCPDV 3296

Query: 165  -----------DSE------------------APDDNSDDSEAPDDNSDDSDVPDDNSDD 195
                       DS+                   P D SD +  P D  D    P +  D 
Sbjct: 3297 TVTPPDGLVVSDSKRGGPVVTGLSTNDPVITATPADFSDVTVTPADFEDVPVTPANCPDV 3356

Query: 196  SSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAP 255
              +  S   SD   D   VP   SDD  V +       VPD  S+     D  ++++ A 
Sbjct: 3357 PVNPESPVVSDLAVDFLVVPVVPSDDLVVLEPPDKVPVVPDPISNGLVVSDPITNNTAAT 3416

Query: 256  DDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDS--SDDSEAPDDKSDDSD 313
            D S D S  P   +D   AP   +D  + +   +DDS  SD    ++  + P   +D  +
Sbjct: 3417 DPSVDGSVVPVSPADGPVAPVTLADCPDVTITPADDSVVSDSKIRAEFEDVPVTIADCPN 3476

Query: 314  VPEDKSDDSDVPDDNSDDLEVPVPAED 340
            VP +      V D   D   VP+P  D
Sbjct: 3477 VPVNPKSGPVVSDLAVDCPVVPIPPPD 3503



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 57/228 (25%), Positives = 88/228 (38%), Gaps = 12/228 (5%)

Query: 138 VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDS- 196
           VP   +DD       ++    P   +D    P  ++D    P   +D   VP   + D  
Sbjct: 648 VPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVIPVTTADGRIVPVTAAGDPI 707

Query: 197 ---SDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSE 253
              +  ++  S   ++D   VP   +D   VP    D   VP  S+D   AP  S+D   
Sbjct: 708 VPVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPV 767

Query: 254 APDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSD 313
            P  S+D   AP  S+D    P   +D        ++       S+D    P   +D   
Sbjct: 768 VPVTSADGPVAPVSSADGPVVPVTPAD--------TNGPAVPVTSADSPFVPVIPADSPV 819

Query: 314 VPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAV 361
           VP   +DD  VP   +D   VPV + D      I +D   +V+++  V
Sbjct: 820 VPVTPADDPIVPVTPADSSFVPVISADSPFVPVIPADGPVVVDSSTDV 867



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 50/205 (24%), Positives = 79/205 (38%), Gaps = 7/205 (3%)

Query: 138  VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSS 197
            +P   +D    P  ++D   +P   +D    P   + D   P   +D    P  ++D   
Sbjct: 1009 IPVTQADSPVVPVTSADRPVSPVTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGPV 1068

Query: 198  DDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDD 257
               +      ++D   VP    D   VP  S+D    P  S+D    P  S+D   AP  
Sbjct: 1069 VPVT------SADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVS 1122

Query: 258  SSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPED 317
            S+D    P   +D    P  ++DD       +D    S   +D    P   +D   +P  
Sbjct: 1123 SADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVLSVTLADSPVVPVTPADSPVIPVP 1182

Query: 318  KSDDSDVPDDNSDDLEVPV-PAEDL 341
             ++   VP  ++D   VPV PA+ L
Sbjct: 1183 PANGPVVPVSSADSPFVPVIPADGL 1207



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 65/272 (23%), Positives = 100/272 (36%), Gaps = 15/272 (5%)

Query: 69   PKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDN 128
            P   A S VV+ + +D          + ++ + S D       V  A   P + ++  D+
Sbjct: 1687 PVTPADSPVVLVTSADSPVIPVTPADSPVVPVTSADTDSPGSPVTSA-DGPVVPVTSADS 1745

Query: 129  DDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDV 188
                   L VP   +D    P  ++D   AP  ++D    P   +D    P   +DD  V
Sbjct: 1746 -------LPVPVTPADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPVVPVTTADDPTV 1798

Query: 189  PDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDS 248
            P   +D      S       ++   VP   +D   VP   +D   V D S+D    P   
Sbjct: 1799 PVTPAD------SPVVPVPPANGPIVPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVSP 1852

Query: 249  SDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDK 308
            +D    PD  +DD       +D    P   +D        +D       S D+   P   
Sbjct: 1853 TDGILVPD-LADDPVVSVTIADSPVIPVTPADSPVVLVTPADGPVVPVTSVDNPVVPVTP 1911

Query: 309  SDDSDVPEDKSDDSDVPDDNSDDLEVPVPAED 340
            +D+  +P    DD  VP   +DD  VPV + D
Sbjct: 1912 ADNPVIPVTPVDDPVVPVTPADDPIVPVTSAD 1943



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 49/200 (24%), Positives = 74/200 (37%), Gaps = 6/200 (3%)

Query: 138  VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSS 197
            VP   +DD       ++    P   +D    P  ++D   +P   +D   VP   + D  
Sbjct: 989  VPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVSPVTTADGRIVPVTAAGDPI 1048

Query: 198  DDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDD 257
               +       +D    P   +D   VP  S+D   VP    D    P  S+D   AP  
Sbjct: 1049 VPVTP------ADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVS 1102

Query: 258  SSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPED 317
            S+D    P  S+D   AP  S+D        +D       ++DD   P   +D   +   
Sbjct: 1103 SADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVLSVT 1162

Query: 318  KSDDSDVPDDNSDDLEVPVP 337
             +D   VP   +D   +PVP
Sbjct: 1163 LADSPVVPVTPADSPVIPVP 1182



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 53/213 (24%), Positives = 79/213 (37%), Gaps = 16/213 (7%)

Query: 138  VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSS 197
            VP  ++D   +P   +D    P   + D   P   +D   +P  ++D   VP  ++D   
Sbjct: 1019 VPVTSADRPVSPVTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSAD--- 1075

Query: 198  DDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDD 257
               S        D   VP   +D    P  S+D   VP  S+D   AP  S+D    P  
Sbjct: 1076 ---SPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVT 1132

Query: 258  SSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPED 317
             +D    P  ++DD   P   +D    S   +D        +D    P   ++   VP  
Sbjct: 1133 PADSPFIPVTTADDPIVPVTPADSPVLSVTLADSPVVPVTPADSPVIPVPPANGPVVPVS 1192

Query: 318  KSDDSDVP----------DDNSDDLEVPVPAED 340
             +D   VP          D ++D L VPV   D
Sbjct: 1193 SADSPFVPVIPADGLVVLDSSTDVLVVPVSPTD 1225



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 52/203 (25%), Positives = 78/203 (38%), Gaps = 4/203 (1%)

Query: 138  VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSS 197
            VP  ++D    P   +D    P   +D    P   +D       ++D   +P   +D  S
Sbjct: 1656 VPVTSADCPVVPVTPADGLVVPVTPADSPIVPVTPADSPVVLVTSADSPVIPVTPAD--S 1713

Query: 198  DDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDD 257
                  S+D +S  S  P   +D   VP  S+D   VP   +D    P  S+D   AP  
Sbjct: 1714 PVVPVTSADTDSPGS--PVTSADGPVVPVTSADSLPVPVTPADGPVVPVTSADGPVAPVS 1771

Query: 258  SSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPED 317
            S+D    P   +D    P  ++DD       +D        ++    P   +D   VP  
Sbjct: 1772 SADGPVVPVTPADSPVVPVTTADDPTVPVTPADSPVVPVPPANGPIVPVTSADSPFVPVI 1831

Query: 318  KSDDSDVPDDNSDDLEVPVPAED 340
             +D   V D ++D L VPV   D
Sbjct: 1832 PADGLVVLDSSTDVLVVPVSPTD 1854



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 55/223 (24%), Positives = 82/223 (36%), Gaps = 19/223 (8%)

Query: 134  NDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNS 193
            N   VP  ++D    P   +D    P   +DD   P   +D S  P  ++D   VP   +
Sbjct: 796  NGPAVPVTSADSPFVPVIPADSPVVPVTPADDPIVPVTPADSSFVPVISADSPFVPVIPA 855

Query: 194  DDSSDDNSDDSSDDN----------------SDDSDVPDDKSDDSDVPDDSSDDSDVPDD 237
            D        DSS D                 +D++ VP + +D   +P    DD  VP  
Sbjct: 856  DGPV---VVDSSTDVLVVPVFPVNCILVPAFADETVVPLNPADSPVIPVTPPDDLVVPVT 912

Query: 238  SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDD 297
             +D   AP  S+D    P   +D    P  ++D    P   +DD       +D    S  
Sbjct: 913  PTDCPVAPVTSADCPVVPVTPADSPADPVTAADGPVVPFTPADDPIVPVTPADSPVVSVT 972

Query: 298  SSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAED 340
             +D    P   +D   VP   +DD  V    ++   +PV   D
Sbjct: 973  PADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQAD 1015



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 49/198 (24%), Positives = 72/198 (36%), Gaps = 6/198 (3%)

Query: 143  SDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSD 202
            +D    P  ++D    P   +DD       ++    P   +D   VP  ++D        
Sbjct: 974  ADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPV----- 1028

Query: 203  DSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDS 262
             S    +D   VP   + D  VP   +D    P  S+D    P  S+D    P    D  
Sbjct: 1029 -SPVTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGP 1087

Query: 263  EAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDS 322
              P  S+D   AP  S+D       S+D   A   S+D    P   +D   +P   +DD 
Sbjct: 1088 VVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDP 1147

Query: 323  DVPDDNSDDLEVPVPAED 340
             VP   +D   + V   D
Sbjct: 1148 IVPVTPADSPVLSVTLAD 1165



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 45/188 (23%), Positives = 71/188 (37%), Gaps = 6/188 (3%)

Query: 153 SDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDS 212
           +D    P   +D    P   +D    P  ++D   VP   +DD         S   ++  
Sbjct: 613 ADSPAVPVTPADSPVVPVTPADGPVVPVASADSPFVPVTPADDPI------VSVTPAESP 666

Query: 213 DVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDS 272
            +P  ++D   VP  S+D   +P  ++D    P  ++ D   P   +D   +P  S+D  
Sbjct: 667 AIPVTQADSPVVPVTSADRPVIPVTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGP 726

Query: 273 EAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDL 332
             P  S+D         D       S+D   AP   +D   VP   +D    P  ++D  
Sbjct: 727 VVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSADGP 786

Query: 333 EVPVPAED 340
            VPV   D
Sbjct: 787 VVPVTPAD 794



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 53/212 (25%), Positives = 78/212 (36%), Gaps = 13/212 (6%)

Query: 138 VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSS 197
           VP    D    P  ++D   AP  ++D    P  ++D   AP  ++D   VP       +
Sbjct: 738 VPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVT----PA 793

Query: 198 DDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDD 257
           D N       ++D   VP   +D   VP   +DD  VP   +D S  P  S+D    P  
Sbjct: 794 DTNGPAVPVTSADSPFVPVIPADSPVVPVTPADDPIVPVTPADSSFVPVISADSPFVPVI 853

Query: 258 SSDDSEAPDDSSDDSEAP---------DDSSDDSEASDDSSDDSEASDDSSDDSEAPDDK 308
            +D     D S+D    P            +D++    + +D         DD   P   
Sbjct: 854 PADGPVVVDSSTDVLVVPVFPVNCILVPAFADETVVPLNPADSPVIPVTPPDDLVVPVTP 913

Query: 309 SDDSDVPEDKSDDSDVPDDNSDDLEVPVPAED 340
           +D    P   +D   VP   +D    PV A D
Sbjct: 914 TDCPVAPVTSADCPVVPVTPADSPADPVTAAD 945



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 57/219 (26%), Positives = 77/219 (35%), Gaps = 18/219 (8%)

Query: 133  GNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDN 192
            G+   VP   +D    P  ++D    P   +D    P   +DD   P    D   VP   
Sbjct: 2570 GDGPVVPVTPADSLVVPVTSADSPVFPVTPADSPVFPVSPADDLVVPVTPGDSPVVPVSP 2629

Query: 193  SDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDS 252
            +D      S       +D   VP   ++   VP  S+D   VP   +D     D S+D  
Sbjct: 2630 AD------SPVVLVTPADGPVVPVTPANGPVVPVTSADSPFVPVIPADGLVVLDSSTDVL 2683

Query: 253  EAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSE--------- 303
              P   +D    PD  +DD   P    DD        DD       +DD           
Sbjct: 2684 VVPVFPTDGILVPD-LADDPVVPVTPGDDPVVPVTPGDDPVIPVTPADDGPFVPVTPAVG 2742

Query: 304  --APDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAED 340
               PD  +DDS VP+  +DD  +     D L VP    D
Sbjct: 2743 PVVPDLTADDSVVPDSLTDDPVISVCPDDGLVVPDTVRD 2781



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 51/203 (25%), Positives = 76/203 (37%), Gaps = 7/203 (3%)

Query: 138 VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSS 197
           VP   +D    P   +D    P   +D    P   +D       ++D   VP   +DD  
Sbjct: 348 VPVTPADSPFVPAIPADGPVVPVTPADSPVVPVTPADGPVVSVASADSPFVPVTPADDPI 407

Query: 198 DDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDD 257
                  S   +D   VP   +D   +P  ++D   VP  ++ D   P   +D   +P  
Sbjct: 408 ------VSVTPADSPVVPVTSADSPLIPVTTADGRVVPVTAAGDPIVPVTPADTPGSPVT 461

Query: 258 SSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPED 317
           S+D    P  S+D    P    D       S+D   A   S+D    P   +D   +P  
Sbjct: 462 SADGPVVPVTSADIPLVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVT 521

Query: 318 KSDDSDVPDDNSDDLEVPV-PAE 339
            +DD  VP   +D   + V PAE
Sbjct: 522 TADDLIVPVTPADSPVLSVTPAE 544



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 50/203 (24%), Positives = 74/203 (36%), Gaps = 6/203 (2%)

Query: 138 VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSS 197
           VP   +DD       +D    P  ++D    P   +D    P   + D  VP   +D   
Sbjct: 398 VPVTPADDPIVSVTPADSPVVPVTSADSPLIPVTTADGRVVPVTAAGDPIVPVTPAD--- 454

Query: 198 DDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDD 257
              +  S   ++D   VP   +D   VP    D   VP  S+D   AP  S+D    P  
Sbjct: 455 ---TPGSPVTSADGPVVPVTSADIPLVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVT 511

Query: 258 SSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPED 317
            +D    P  ++DD   P   +D    S   ++        +D    P   ++   VP  
Sbjct: 512 PADSPFIPVTTADDLIVPVTPADSPVLSVTPAESPAIPVTPADSPIVPVTPANGPVVPVT 571

Query: 318 KSDDSDVPDDNSDDLEVPVPAED 340
            +D   VP   +D   VPV   D
Sbjct: 572 SADSPFVPVIPADGPVVPVTPAD 594



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 63/248 (25%), Positives = 87/248 (35%), Gaps = 27/248 (10%)

Query: 120  PIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSE-APDDNSDDSEA 178
            P+  +D     D  +D  VP    DD   P    DD   P   +DD    P   +     
Sbjct: 2686 PVFPTDGILVPDLADDPVVPVTPGDDPVVPVTPGDDPVIPVTPADDGPFVPVTPAVGPVV 2745

Query: 179  PDDNSDDSDVPDDNSDDSSDDNSDDSS---DDNSDDSDVPD------------DKSDDSD 223
            PD  +DDS VPD  +DD       D      D   DSD P+            D + D  
Sbjct: 2746 PDLTADDSVVPDSLTDDPVISVCPDDGLVVPDTVRDSDGPEVSVYPVTGPVVTDSAADCP 2805

Query: 224  VPDDSSDDS--------DVP---DDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDS 272
            V      D         +VP   D  ++    PD   D     + S D    P  S+D+ 
Sbjct: 2806 VVSVPLTDGLVVLCPPDEVPAVHDSVTNGLVVPDPVIDGPVFSNPSVDGPIVPVASADNP 2865

Query: 273  EAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDL 332
              PD           S+     +   +D  +     +D +DVP +  +   VPD + D  
Sbjct: 2866 GVPDPIRAFPVVPKPSTFSPVVTSTPADWIDVIVTPADCADVPVNPVNGPVVPDLSGDCP 2925

Query: 333  EVPVPAED 340
             VPVP  D
Sbjct: 2926 VVPVPPTD 2933



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 51/209 (24%), Positives = 77/209 (36%), Gaps = 7/209 (3%)

Query: 138  VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSS 197
            VP   +D    P   +D    P   +D       ++D    P   +D   VP  ++D  S
Sbjct: 1666 VPVTPADGLVVPVTPADSPIVPVTPADSPVVLVTSADSPVIPVTPADSPVVPVTSADTDS 1725

Query: 198  DDNSDDSSDD------NSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDD 251
              +   S+D       ++D   VP   +D   VP  S+D    P  S+D    P   +D 
Sbjct: 1726 PGSPVTSADGPVVPVTSADSLPVPVTPADGPVVPVTSADGPVAPVSSADGPVVPVTPADS 1785

Query: 252  SEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDD 311
               P  ++DD   P   +D    P   ++       S+D        +D     D  +D 
Sbjct: 1786 PVVPVTTADDPTVPVTPADSPVVPVPPANGPIVPVTSADSPFVPVIPADGLVVLDSSTDV 1845

Query: 312  SDVPEDKSDDSDVPDDNSDDLEVPVPAED 340
              VP   +D   VP D +DD  V V   D
Sbjct: 1846 LVVPVSPTDGILVP-DLADDPVVSVTIAD 1873



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 54/216 (25%), Positives = 79/216 (36%), Gaps = 14/216 (6%)

Query: 138  VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSD--- 194
            VP   +D    P   +DD   P   +D    P   ++    P  ++D   VP   +D   
Sbjct: 1778 VPVTPADSPVVPVTTADDPTVPVTPADSPVVPVPPANGPIVPVTSADSPFVPVIPADGLV 1837

Query: 195  --DSSDD--------NSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEA 244
              DSS D               D +DD  V    +D   +P   +D   V    +D    
Sbjct: 1838 VLDSSTDVLVVPVSPTDGILVPDLADDPVVSVTIADSPVIPVTPADSPVVLVTPADGPVV 1897

Query: 245  PDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEA 304
            P  S D+   P   +D+   P    DD   P   +DD      S+D    S   +D    
Sbjct: 1898 PVTSVDNPVVPVTPADNPVIPVTPVDDPVVPVTPADDPIVPVTSADSPIVSVTPADSPVF 1957

Query: 305  PDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPV-PAE 339
            P   +D   +P   +D   VP   +D + VPV PA+
Sbjct: 1958 PVTPADSPVIPVASADSPLVPVTPADMVVVPVIPAD 1993



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 48/202 (23%), Positives = 76/202 (37%), Gaps = 7/202 (3%)

Query: 139  PDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSD 198
            P  ++D    P  ++D    P    D    P  ++D   AP  ++D   VP  ++D    
Sbjct: 1060 PVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVA 1119

Query: 199  DNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDS 258
              S      ++D   VP   +D   +P  ++DD  VP   +D        +D    P   
Sbjct: 1120 PVS------SADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVLSVTLADSPVVPVTP 1173

Query: 259  SDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDK 318
            +D    P   ++    P  S+D        +D     D S+D    P   +D   VP D 
Sbjct: 1174 ADSPVIPVPPANGPVVPVSSADSPFVPVIPADGLVVLDSSTDVLVVPVSPTDGILVP-DL 1232

Query: 319  SDDSDVPDDNSDDLEVPVPAED 340
            +DD  V    +D   +PV   D
Sbjct: 1233 ADDPVVSVTIADSPVIPVTPAD 1254



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 56/231 (24%), Positives = 87/231 (37%), Gaps = 11/231 (4%)

Query: 114 PAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 173
           P I    +V+ D   D      L VP   +D    PD  +D+   P   +DD   P   +
Sbjct: 51  PVIPADGLVVLDSSTDV-----LVVPVFPADGILVPDF-ADNPVVPVTPADDLVFPVTPA 104

Query: 174 DDSEAPDDNSDDSDVPDDNSDDS----SDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSS 229
           D    P  ++DD  VP   +D+     +  N        +D    P   +D   VP   +
Sbjct: 105 DSPVIPVTSADDPVVPITPADNPVVPVTSANGPVIPVTPADSPVFPVASADGPVVPVTPA 164

Query: 230 DDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSS 289
           D    P   +D    P   +D    P   +D +  P   +D        ++ +      +
Sbjct: 165 DSPVFPVTPADSPLFPVTPADSPLFPVTPADSAAIPVTPADGPVVHVTPANGTVVPVTPA 224

Query: 290 DDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPV-PAE 339
           D    +  S+D    P   +DD  VP   +D S VP  ++D   VPV PA+
Sbjct: 225 DSPVVTVASTDSPVVPVTPADDPIVPVTPADSSFVPVISADSPFVPVIPAD 275



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 50/207 (24%), Positives = 72/207 (34%), Gaps = 4/207 (1%)

Query: 134  NDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNS 193
            +DL VP   +D        +D    P   +D       ++D    P   +D   VP   +
Sbjct: 2112 DDLIVPVTPADSLIVSVTPADSPVVPVTPADSPVISVASADSPVVPVTPADTVVVPVTPA 2171

Query: 194  DDS----SDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSS 249
            D      +   S       +D   VP   +DD  VP   +D   VP   + D   P   +
Sbjct: 2172 DGPVIPVTPAESPAIPVTPADSPVVPVTPADDPVVPVTPADSPIVPVPPASDPVVPVTPA 2231

Query: 250  DDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKS 309
            D   +P  S+D    P  S+D    P    D        +D       S+D    P   +
Sbjct: 2232 DTPGSPVASADGPVVPVTSADSPLVPVTPGDSPVVPVTPADSPVFPVTSADGPVFPVTLA 2291

Query: 310  DDSDVPEDKSDDSDVPDDNSDDLEVPV 336
            DD   P   +DD   P   +D   VPV
Sbjct: 2292 DDPVFPVTPADDPIFPVSPADSPVVPV 2318



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 36/129 (27%), Positives = 50/129 (38%)

Query: 209  SDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDS 268
            +DD  VP   +D   VP   + D  VP   +D   +P  S+D    P  S+D    P   
Sbjct: 2201 ADDPVVPVTPADSPIVPVPPASDPVVPVTPADTPGSPVASADGPVVPVTSADSPLVPVTP 2260

Query: 269  SDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDN 328
             D    P   +D       S+D        +DD   P   +DD   P   +D   VP   
Sbjct: 2261 GDSPVVPVTPADSPVFPVTSADGPVFPVTLADDPVFPVTPADDPIFPVSPADSPVVPVTP 2320

Query: 329  SDDLEVPVP 337
            ++   VPVP
Sbjct: 2321 ANIPVVPVP 2329



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 61/268 (22%), Positives = 93/268 (34%), Gaps = 27/268 (10%)

Query: 73   ASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDN 132
            A  +VV+DS +D            ++ ++  D  P    V     +P + ++  D+    
Sbjct: 2351 ADGLVVLDSSTD----------VLVVLVSPTDGIP----VPDLADDPVVSVTTSDSP--- 2393

Query: 133  GNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDN 192
                 +P   +D    P   +D    P  + D    P   +D    P   +D   VP   
Sbjct: 2394 ----VIPVTPTDSPVVPVAPADGPVVPVTSVDSPVVPVTPADSPVIPVTPADSLVVPATP 2449

Query: 193  SDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDS 252
            +DD         S   +D   VP   +D   +   S+D   VP   +D    P  S+D  
Sbjct: 2450 ADDPV------VSVTPADGPVVPVTTADIPVISVTSADSPVVPVTPADGLVVPVTSADSV 2503

Query: 253  EAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDS 312
              P   +D    P D +D         D+   S  S D        +D S  P   +   
Sbjct: 2504 VVPATPADCPLVPVDPADSPIVLFTPYDNPVVSVTSDDSPVFPVTPADSSVVPVTPAGVP 2563

Query: 313  DVPEDKSDDSDVPDDNSDDLEVPVPAED 340
             VP    D   VP   +D L VPV + D
Sbjct: 2564 VVPVTPGDGPVVPVTPADSLVVPVTSAD 2591



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 47/204 (23%), Positives = 71/204 (34%), Gaps = 6/204 (2%)

Query: 138  VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSS 197
            VP  ++D    P   +DD   P   +D        ++    P   +D   VP  ++D   
Sbjct: 1327 VPVTSADSPFVPVTPADDPIVPVTPADSPIVSVTPAESPAIPVTPADSPVVPVTSADSPL 1386

Query: 198  DDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDD 257
               +   S        VP   + D  VP   +D    P  S+D    P   + D   P  
Sbjct: 1387 IPLTTAGS------RVVPVTPTGDPIVPVTPADTPGSPVTSADGPVVPVTPAGDPIVPVT 1440

Query: 258  SSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPED 317
             +D   +P  S+D    P  + D         D       S+D    P   +D   +P  
Sbjct: 1441 PADTPGSPVTSADGPVVPVTTPDGPLVPVSPPDGPVVPVTSADGPVVPVTPADSPFIPVT 1500

Query: 318  KSDDSDVPDDNSDDLEVPVPAEDL 341
             +DD  VP   +D   VPV   D+
Sbjct: 1501 TADDPIVPVTPADSPVVPVTPADI 1524



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 55/216 (25%), Positives = 81/216 (37%), Gaps = 14/216 (6%)

Query: 138  VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSD--- 194
            VP   +DD   P   +D    P   ++    P  ++D    P   +D   V D ++D   
Sbjct: 1788 VPVTTADDPTVPVTPADSPVVPVPPANGPIVPVTSADSPFVPVIPADGLVVLDSSTDVLV 1847

Query: 195  ---DSSD-----DNSDDS--SDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEA 244
                 +D     D +DD   S   +D   +P   +D   V    +D   VP  S D+   
Sbjct: 1848 VPVSPTDGILVPDLADDPVVSVTIADSPVIPVTPADSPVVLVTPADGPVVPVTSVDNPVV 1907

Query: 245  PDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEA 304
            P   +D+   P    DD   P   +DD   P  S+D    S   +D        +D    
Sbjct: 1908 PVTPADNPVIPVTPVDDPVVPVTPADDPIVPVTSADSPIVSVTPADSPVFPVTPADSPVI 1967

Query: 305  PDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPV-PAE 339
            P   +D   VP   +D   VP   +D   +PV PAE
Sbjct: 1968 PVASADSPLVPVTPADMVVVPVIPADGPVIPVTPAE 2003



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 50/217 (23%), Positives = 81/217 (37%), Gaps = 13/217 (5%)

Query: 138  VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDS- 196
            VP   +D   +P  ++D    P   + D   P   +D   +P  ++D   VP    D   
Sbjct: 1407 VPVTPADTPGSPVTSADGPVVPVTPAGDPIVPVTPADTPGSPVTSADGPVVPVTTPDGPL 1466

Query: 197  ---SDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSE 253
               S  +       ++D   VP   +D   +P  ++DD  VP   +D    P   +D   
Sbjct: 1467 VPVSPPDGPVVPVTSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVVPVTPADIPV 1526

Query: 254  APDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSD---------DSEASDDSSDDSEA 304
             P   ++       S+D    P   +D   A D S+D         D     D +DD   
Sbjct: 1527 VPVTPANGPVIHVTSADCPFVPVIPADGLVALDSSTDVLVVPVSPTDGVLVPDLADDPVV 1586

Query: 305  PDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDL 341
                +D   +P   +D + VP   +D   VPV + D+
Sbjct: 1587 SVTIADSPVIPVTPADSTVVPVTLADGPVVPVTSVDI 1623



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 50/227 (22%), Positives = 84/227 (37%), Gaps = 16/227 (7%)

Query: 120 PIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAP 179
           P+  +D     D  ++  VP   +DD   P   +D    P  ++DD   P   +D+   P
Sbjct: 71  PVFPADGILVPDFADNPVVPVTPADDLVFPVTPADSPVIPVTSADDPVVPITPADNPVVP 130

Query: 180 DDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSS 239
             +++   +P   +D      S      ++D   VP   +D    P   +D    P   +
Sbjct: 131 VTSANGPVIPVTPAD------SPVFPVASADGPVVPVTPADSPVFPVTPADSPLFPVTPA 184

Query: 240 DDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSS 299
           D    P   +D +  P   +D        ++ +  P   +D    +  S+D        +
Sbjct: 185 DSPLFPVTPADSAAIPVTPADGPVVHVTPANGTVVPVTPADSPVVTVASTDSPVVPVTPA 244

Query: 300 DDSEAPDDKSDDSDVPEDKSDDSDVP----------DDNSDDLEVPV 336
           DD   P   +D S VP   +D   VP          D ++D L VPV
Sbjct: 245 DDPIVPVTPADSSFVPVISADSPFVPVIPADGPVVVDSSTDVLVVPV 291



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 48/215 (22%), Positives = 75/215 (34%), Gaps = 14/215 (6%)

Query: 138 VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDS----------D 187
           VP  ++D   AP  ++D    P   +D    P   +DD   P   +D             
Sbjct: 488 VPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDLIVPVTPADSPVLSVTPAESPA 547

Query: 188 VPDDNSDDS----SDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSE 243
           +P   +D      +  N       ++D   VP   +D   VP   +D   VP   +D   
Sbjct: 548 IPVTPADSPIVPVTPANGPVVPVTSADSPFVPVIPADGPVVPVTPADSPVVPVTPADSPV 607

Query: 244 APDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSE 303
                +D    P   +D    P   +D    P  S+D        +DD   S   ++   
Sbjct: 608 LSVTLADSPAVPVTPADSPVVPVTPADGPVVPVASADSPFVPVTPADDPIVSVTPAESPA 667

Query: 304 APDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPA 338
            P  ++D   VP   +D   +P   +D   VPV A
Sbjct: 668 IPVTQADSPVVPVTSADRPVIPVTTADGRIVPVTA 702



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 63/271 (23%), Positives = 91/271 (33%), Gaps = 12/271 (4%)

Query: 138  VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSS 197
            VP   +D    P   +D    P   ++    P   +D    P   +DD  VP   +D   
Sbjct: 2156 VPVTPADTVVVPVTPADGPVIPVTPAESPAIPVTPADSPVVPVTPADDPVVPVTPAD--- 2212

Query: 198  DDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDD 257
               S       + D  VP   +D    P  S+D   VP  S+D    P    D    P  
Sbjct: 2213 ---SPIVPVPPASDPVVPVTPADTPGSPVASADGPVVPVTSADSPLVPVTPGDSPVVPVT 2269

Query: 258  SSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPED 317
             +D    P  S+D    P   +DD       +DD       +D    P   ++   VP  
Sbjct: 2270 PADSPVFPVTSADGPVFPVTLADDPVFPVTPADDPIFPVSPADSPVVPVTPANIPVVPVP 2329

Query: 318  KSDDSDVPDDNSDDLEVP-VPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLG 376
             ++ S VP  ++    VP +PA+ L            LV     +   D +DD       
Sbjct: 2330 PANGSVVPVTSAGSPFVPIIPADGLVVLDSSTDVLVVLVSPTDGIPVPDLADDPVVSVTT 2389

Query: 377  ENLSKPPSDPEANPEVSERKLPTEEEPAPVV 407
             +    P  P  +P V     P      PVV
Sbjct: 2390 SDSPVIPVTPTDSPVV-----PVAPADGPVV 2415



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 52/212 (24%), Positives = 74/212 (34%), Gaps = 7/212 (3%)

Query: 131  DNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPD 190
            D  +D  V    SD    P   +D    P   +D    P  + D    P   +D   +P 
Sbjct: 2378 DLADDPVVSVTTSDSPVIPVTPTDSPVVPVAPADGPVVPVTSVDSPVVPVTPADSPVIPV 2437

Query: 191  DNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSD 250
              +D      +       +DD  V    +D   VP  ++D   +   S+D    P   +D
Sbjct: 2438 TPADSLVVPATP------ADDPVVSVTPADGPVVPVTTADIPVISVTSADSPVVPVTPAD 2491

Query: 251  DSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSD 310
                P  S+D    P   +D    P D +D         D+   S  S D    P   +D
Sbjct: 2492 GLVVPVTSADSVVVPATPADCPLVPVDPADSPIVLFTPYDNPVVSVTSDDSPVFPVTPAD 2551

Query: 311  DSDVPEDKSDDSDVPDDNSDDLEVPV-PAEDL 341
             S VP   +    VP    D   VPV PA+ L
Sbjct: 2552 SSVVPVTPAGVPVVPVTPGDGPVVPVTPADSL 2583



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 50/216 (23%), Positives = 73/216 (33%), Gaps = 13/216 (6%)

Query: 138 VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVP-------- 189
           VP   +DD   P   +D S  P  ++D    P   +D     D ++D   VP        
Sbjct: 239 VPVTPADDPIVPVTPADSSFVPVISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCIL 298

Query: 190 -----DDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEA 244
                D+         S   S   +DD  VP   +D   +    +D   VP   +D    
Sbjct: 299 VPAFADETIXXXXXXXSLVVSVTTADDPIVPVTPADSPVLSVTLADSPVVPVTPADSPFV 358

Query: 245 PDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEA 304
           P   +D    P   +D    P   +D       S+D        +DD   S   +D    
Sbjct: 359 PAIPADGPVVPVTPADSPVVPVTPADGPVVSVASADSPFVPVTPADDPIVSVTPADSPVV 418

Query: 305 PDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAED 340
           P   +D   +P   +D   VP   + D  VPV   D
Sbjct: 419 PVTSADSPLIPVTTADGRVVPVTAAGDPIVPVTPAD 454



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 57/224 (25%), Positives = 80/224 (35%), Gaps = 23/224 (10%)

Query: 138  VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVP-------- 189
            VP   +DD   P   +D S  P  ++D    P   +D     D ++D   VP        
Sbjct: 820  VPVTPADDPIVPVTPADSSFVPVISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCIL 879

Query: 190  -----DDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEA 244
                 D+     +  +S        DD  VP   +D    P  S+D   VP   +D    
Sbjct: 880  VPAFADETVVPLNPADSPVIPVTPPDDLVVPVTPTDCPVAPVTSADCPVVPVTPADSPAD 939

Query: 245  PDDSSDDSEAPDDSSDD---SEAPDDSSDDSEAPDDSSDDSEASDDS-------SDDSEA 294
            P  ++D    P   +DD      P DS   S  P D      AS DS       +DD   
Sbjct: 940  PVTAADGPVVPFTPADDPIVPVTPADSPVVSVTPADGPVVPVASADSPFVPVTPADDPIV 999

Query: 295  SDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPA 338
            S   ++    P  ++D   VP   +D    P   +D   VPV A
Sbjct: 1000 SVTPAESPAIPVTQADSPVVPVTSADRPVSPVTTADGRIVPVTA 1043



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 51/213 (23%), Positives = 77/213 (36%), Gaps = 9/213 (4%)

Query: 134  NDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNS 193
            +D   P   +DD   P   +D    P   ++    P   ++ S  P  ++    VP   +
Sbjct: 2292 DDPVFPVTPADDPIFPVSPADSPVVPVTPANIPVVPVPPANGSVVPVTSAGSPFVPIIPA 2351

Query: 194  DDSSDDNSDDSSD------DNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDD 247
            D       D S+D        +D   VPD  +DD  V   +SD   +P   +D    P  
Sbjct: 2352 DGLVV--LDSSTDVLVVLVSPTDGIPVPD-LADDPVVSVTTSDSPVIPVTPTDSPVVPVA 2408

Query: 248  SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDD 307
             +D    P  S D    P   +D    P   +D        +DD   S   +D    P  
Sbjct: 2409 PADGPVVPVTSVDSPVVPVTPADSPVIPVTPADSLVVPATPADDPVVSVTPADGPVVPVT 2468

Query: 308  KSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAED 340
             +D   +    +D   VP   +D L VPV + D
Sbjct: 2469 TADIPVISVTSADSPVVPVTPADGLVVPVTSAD 2501



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 54/217 (24%), Positives = 80/217 (36%), Gaps = 15/217 (6%)

Query: 138  VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDD-- 195
            VP  ++D    P   +D    P   +DD   P   +D    P   +D   VP   ++   
Sbjct: 1477 VPVTSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVVPVTPADIPVVPVTPANGPV 1536

Query: 196  ----SSD--------DNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSE 243
                S+D         +   + D ++D   VP   +D   VP D +DD  V    +D   
Sbjct: 1537 IHVTSADCPFVPVIPADGLVALDSSTDVLVVPVSPTDGVLVP-DLADDPVVSVTIADSPV 1595

Query: 244  APDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSE 303
             P   +D +  P   +D    P  S D    P   ++   A     DD   S + +D S 
Sbjct: 1596 IPVTPADSTVVPVTLADGPVVPVTSVDIPVVPVTPANGPVAPVTPVDDPVVSVNPADGSV 1655

Query: 304  APDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAED 340
             P   +D   VP   +D   VP   +D   VPV   D
Sbjct: 1656 VPVTSADCPVVPVTPADGLVVPVTPADSPIVPVTPAD 1692



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 40/140 (28%), Positives = 53/140 (37%), Gaps = 9/140 (6%)

Query: 210  DDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSS 269
            DD  VP   +DD  VP  S+D   V    +D    P   +D    P  S+D    P   +
Sbjct: 1923 DDPVVPVTPADDPIVPVTSADSPIVSVTPADSPVFPVTPADSPVIPVASADSPLVPVTPA 1982

Query: 270  DDSEAPDDSSD---------DSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSD 320
            D    P   +D         +S A   +  DS     +S DS      +D   VP   +D
Sbjct: 1983 DMVVVPVIPADGPVIPVTPAESPAIPVTPTDSPVVPVTSADSPVIPVTADSPFVPVTPAD 2042

Query: 321  DSDVPDDNSDDLEVPVPAED 340
               +P    DDL VPV   D
Sbjct: 2043 SPVIPVTPPDDLVVPVTPID 2062



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 51/209 (24%), Positives = 73/209 (34%), Gaps = 14/209 (6%)

Query: 142  NSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDV---PDDNSDDS-S 197
            ++D    P   +D    P  ++D    P   +D    P D +D   V   P DN   S +
Sbjct: 2479 SADSPVVPVTPADGLVVPVTSADSVVVPATPADCPLVPVDPADSPIVLFTPYDNPVVSVT 2538

Query: 198  DDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDD 257
             D+S       +D S VP   +    VP    D   VP   +D    P  S+D    P  
Sbjct: 2539 SDDSPVFPVTPADSSVVPVTPAGVPVVPVTPGDGPVVPVTPADSLVVPVTSADSPVFPVT 2598

Query: 258  SSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPED 317
             +D    P   +DD   P    D        +D        +D    P   ++   VP  
Sbjct: 2599 PADSPVFPVSPADDLVVPVTPGDSPVVPVSPADSPVVLVTPADGPVVPVTPANGPVVPVT 2658

Query: 318  KSDDSDVP----------DDNSDDLEVPV 336
             +D   VP          D ++D L VPV
Sbjct: 2659 SADSPFVPVIPADGLVVLDSSTDVLVVPV 2687



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 45/195 (23%), Positives = 68/195 (34%), Gaps = 6/195 (3%)

Query: 142  NSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNS 201
            ++D    P   +D    P   +D    P   ++    P   +D   VP   +DD     +
Sbjct: 2150 SADSPVVPVTPADTVVVPVTPADGPVIPVTPAESPAIPVTPADSPVVPVTPADDPVVPVT 2209

Query: 202  DDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDD 261
                   +D   VP   + D  VP   +D    P  S+D    P  S+D    P    D 
Sbjct: 2210 P------ADSPIVPVPPASDPVVPVTPADTPGSPVASADGPVVPVTSADSPLVPVTPGDS 2263

Query: 262  SEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDD 321
               P   +D    P  S+D        +DD       +DD   P   +D   VP   ++ 
Sbjct: 2264 PVVPVTPADSPVFPVTSADGPVFPVTLADDPVFPVTPADDPIFPVSPADSPVVPVTPANI 2323

Query: 322  SDVPDDNSDDLEVPV 336
              VP   ++   VPV
Sbjct: 2324 PVVPVPPANGSVVPV 2338



 Score = 38.9 bits (89), Expect = 0.016
 Identities = 52/215 (24%), Positives = 78/215 (36%), Gaps = 13/215 (6%)

Query: 138  VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD---DSDVPDDNSD 194
            VP  ++D    P   +D     D ++D    P   +D    PD   D      + D    
Sbjct: 1818 VPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVSPTDGILVPDLADDPVVSVTIADSPVI 1877

Query: 195  DSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEA 254
              +  +S       +D   VP    D+  VP   +D+  +P    DD   P   +DD   
Sbjct: 1878 PVTPADSPVVLVTPADGPVVPVTSVDNPVVPVTPADNPVIPVTPVDDPVVPVTPADDPIV 1937

Query: 255  PDDSSDD---SEAPDDSSDDSEAPDDSSDDSEASDDS-------SDDSEASDDSSDDSEA 304
            P  S+D    S  P DS      P DS     AS DS       +D        +D    
Sbjct: 1938 PVTSADSPIVSVTPADSPVFPVTPADSPVIPVASADSPLVPVTPADMVVVPVIPADGPVI 1997

Query: 305  PDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAE 339
            P   ++   +P   +D   VP  ++D   +PV A+
Sbjct: 1998 PVTPAESPAIPVTPTDSPVVPVTSADSPVIPVTAD 2032



 Score = 38.5 bits (88), Expect = 0.021
 Identities = 47/198 (23%), Positives = 69/198 (34%), Gaps = 17/198 (8%)

Query: 143  SDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSD 202
            +D    P  + D+   P   +D+   P    DD   P   +DD  VP  ++D      S 
Sbjct: 1892 ADGPVVPVTSVDNPVVPVTPADNPVIPVTPVDDPVVPVTPADDPIVPVTSAD------SP 1945

Query: 203  DSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDS 262
              S   +D    P   +D   +P  S+D   VP   +D    P   +D    P   ++  
Sbjct: 1946 IVSVTPADSPVFPVTPADSPVIPVASADSPLVPVTPADMVVVPVIPADGPVIPVTPAESP 2005

Query: 263  EAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDS 322
              P   +D    P  S+D           S     ++D    P   +D   +P    DD 
Sbjct: 2006 AIPVTPTDSPVVPVTSAD-----------SPVIPVTADSPFVPVTPADSPVIPVTPPDDL 2054

Query: 323  DVPDDNSDDLEVPVPAED 340
             VP    D   VPV   D
Sbjct: 2055 VVPVTPIDCPVVPVTLVD 2072



 Score = 38.1 bits (87), Expect = 0.027
 Identities = 55/210 (26%), Positives = 71/210 (33%), Gaps = 10/210 (4%)

Query: 135  DLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSD 194
            D  V    S DS      +D    P   +D    P    DD   P    D   VP    D
Sbjct: 2013 DSPVVPVTSADSPVIPVTADSPFVPVTPADSPVIPVTPPDDLVVPVTPIDCPVVPVTLVD 2072

Query: 195  ----DSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDD---SEAPDD 247
                  +  NS       +D   VP   +D   +P   +DD  VP   +D    S  P D
Sbjct: 2073 CPVVSVTPANSPVDPVTPADGPVVPVTPADSPVIPVTPADDLIVPVTPADSLIVSVTPAD 2132

Query: 248  SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDD 307
            S      P DS   S A   S+D    P   +D        +D        ++    P  
Sbjct: 2133 SPVVPVTPADSPVISVA---SADSPVVPVTPADTVVVPVTPADGPVIPVTPAESPAIPVT 2189

Query: 308  KSDDSDVPEDKSDDSDVPDDNSDDLEVPVP 337
             +D   VP   +DD  VP   +D   VPVP
Sbjct: 2190 PADSPVVPVTPADDPVVPVTPADSPIVPVP 2219



 Score = 37.7 bits (86), Expect = 0.036
 Identities = 55/241 (22%), Positives = 83/241 (34%), Gaps = 20/241 (8%)

Query: 114  PAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 173
            P I    +V+ D   D      L VP   +D    PD  +DD       +D    P   +
Sbjct: 1200 PVIPADGLVVLDSSTDV-----LVVPVSPTDGILVPD-LADDPVVSVTIADSPVIPVTPA 1253

Query: 174  DDSEAPDDNSDDSDVPDDNSDDS-------SDDNSDDSSD------DNSDDSDVPDDKSD 220
            D    P  ++D   VP   +D             S  ++D        +D   +P   +D
Sbjct: 1254 DSPVVPVTSADSPVVPVTPADSPVILVTPVGPVVSVTTADGPVVLVSTADSPVIPVTSAD 1313

Query: 221  DSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSD 280
               VP   +D   VP  S+D    P   +DD   P   +D        ++    P   +D
Sbjct: 1314 SPVVPVTPADGPVVPVTSADSPFVPVTPADDPIVPVTPADSPIVSVTPAESPAIPVTPAD 1373

Query: 281  DSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPV-PAE 339
                   S+D       ++     P   + D  VP   +D    P  ++D   VPV PA 
Sbjct: 1374 SPVVPVTSADSPLIPLTTAGSRVVPVTPTGDPIVPVTPADTPGSPVTSADGPVVPVTPAG 1433

Query: 340  D 340
            D
Sbjct: 1434 D 1434



 Score = 37.7 bits (86), Expect = 0.036
 Identities = 51/213 (23%), Positives = 74/213 (34%), Gaps = 5/213 (2%)

Query: 133  GNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDN 192
            G+   VP   +D    P  ++D    P   +DD   P   +DD   P   +D   VP   
Sbjct: 2261 GDSPVVPVTPADSPVFPVTSADGPVFPVTLADDPVFPVTPADDPIFPVSPADSPVVPVTP 2320

Query: 193  SD----DSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDS 248
            ++         N       ++    VP   +D   V D S+D   V    +D    PD  
Sbjct: 2321 ANIPVVPVPPANGSVVPVTSAGSPFVPIIPADGLVVLDSSTDVLVVLVSPTDGIPVPD-L 2379

Query: 249  SDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDK 308
            +DD      +SD    P   +D    P   +D       S D        +D    P   
Sbjct: 2380 ADDPVVSVTTSDSPVIPVTPTDSPVVPVAPADGPVVPVTSVDSPVVPVTPADSPVIPVTP 2439

Query: 309  SDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDL 341
            +D   VP   +DD  V    +D   VPV   D+
Sbjct: 2440 ADSLVVPATPADDPVVSVTPADGPVVPVTTADI 2472



 Score = 37.7 bits (86), Expect = 0.036
 Identities = 52/217 (23%), Positives = 72/217 (33%), Gaps = 14/217 (6%)

Query: 138  VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSD--- 194
            VP  + D    P   +D    P   +D    P   +DD       +D   VP   +D   
Sbjct: 2415 VPVTSVDSPVVPVTPADSPVIPVTPADSLVVPATPADDPVVSVTPADGPVVPVTTADIPV 2474

Query: 195  -DSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSD---------DSEA 244
               +  +S       +D   VP   +D   VP   +D   VP D +D         D+  
Sbjct: 2475 ISVTSADSPVVPVTPADGLVVPVTSADSVVVPATPADCPLVPVDPADSPIVLFTPYDNPV 2534

Query: 245  PDDSSDDSEA-PDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSE 303
               +SDDS   P   +D S  P   +     P    D        +D       S+D   
Sbjct: 2535 VSVTSDDSPVFPVTPADSSVVPVTPAGVPVVPVTPGDGPVVPVTPADSLVVPVTSADSPV 2594

Query: 304  APDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAED 340
             P   +D    P   +DD  VP    D   VPV   D
Sbjct: 2595 FPVTPADSPVFPVSPADDLVVPVTPGDSPVVPVSPAD 2631



 Score = 37.4 bits (85), Expect = 0.047
 Identities = 31/130 (23%), Positives = 48/130 (36%)

Query: 211 DSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSD 270
           D  +  D +D+  VP   +DD   P   +D    P  S+DD   P   +D+   P  S++
Sbjct: 76  DGILVPDFADNPVVPVTPADDLVFPVTPADSPVIPVTSADDPVVPITPADNPVVPVTSAN 135

Query: 271 DSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSD 330
               P   +D       S+D        +D    P   +D    P   +D    P   +D
Sbjct: 136 GPVIPVTPADSPVFPVASADGPVVPVTPADSPVFPVTPADSPLFPVTPADSPLFPVTPAD 195

Query: 331 DLEVPVPAED 340
              +PV   D
Sbjct: 196 SAAIPVTPAD 205



 Score = 37.0 bits (84), Expect = 0.061
 Identities = 32/133 (24%), Positives = 49/133 (36%)

Query: 209 SDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDS 268
           +D   VP   +D   VP   +D   VP   +D    P   +D       S+D    P   
Sbjct: 343 ADSPVVPVTPADSPFVPAIPADGPVVPVTPADSPVVPVTPADGPVVSVASADSPFVPVTP 402

Query: 269 SDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDN 328
           +DD       +D       S+D       ++D    P   + D  VP   +D    P  +
Sbjct: 403 ADDPIVSVTPADSPVVPVTSADSPLIPVTTADGRVVPVTAAGDPIVPVTPADTPGSPVTS 462

Query: 329 SDDLEVPVPAEDL 341
           +D   VPV + D+
Sbjct: 463 ADGPVVPVTSADI 475



 Score = 36.6 bits (83), Expect = 0.080
 Identities = 35/135 (25%), Positives = 52/135 (38%), Gaps = 1/135 (0%)

Query: 206 DDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAP 265
           D ++D   VP   +D   VPD  +D+  VP   +DD   P   +D    P  S+DD   P
Sbjct: 62  DSSTDVLVVPVFPADGILVPD-FADNPVVPVTPADDLVFPVTPADSPVIPVTSADDPVVP 120

Query: 266 DDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVP 325
              +D+   P  S++        +D       S+D    P   +D    P   +D    P
Sbjct: 121 ITPADNPVVPVTSANGPVIPVTPADSPVFPVASADGPVVPVTPADSPVFPVTPADSPLFP 180

Query: 326 DDNSDDLEVPVPAED 340
              +D    PV   D
Sbjct: 181 VTPADSPLFPVTPAD 195



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 44/194 (22%), Positives = 69/194 (35%), Gaps = 7/194 (3%)

Query: 149  PDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDN 208
            P   +D    P  ++D    P   +     P   + D  VP   +D      +  S   +
Sbjct: 1368 PVTPADSPVVPVTSADSPLIPLTTAGSRVVPVTPTGDPIVPVTPAD------TPGSPVTS 1421

Query: 209  SDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDS 268
            +D   VP   + D  VP   +D    P  S+D    P  + D    P    D    P  S
Sbjct: 1422 ADGPVVPVTPAGDPIVPVTPADTPGSPVTSADGPVVPVTTPDGPLVPVSPPDGPVVPVTS 1481

Query: 269  SDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDN 328
            +D    P   +D       ++DD       +D    P   +D   VP   ++   +   +
Sbjct: 1482 ADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVVPVTPADIPVVPVTPANGPVIHVTS 1541

Query: 329  SDDLEVPV-PAEDL 341
            +D   VPV PA+ L
Sbjct: 1542 ADCPFVPVIPADGL 1555



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 62/239 (25%), Positives = 84/239 (35%), Gaps = 34/239 (14%)

Query: 136  LEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEA---PDDN------SDDSEA-PDDNSDD 185
            L VP  ++D    P   +D    P D +D       P DN      SDDS   P   +D 
Sbjct: 2493 LVVPVTSADSVVVPATPADCPLVPVDPADSPIVLFTPYDNPVVSVTSDDSPVFPVTPADS 2552

Query: 186  SDVPDDNSD----DSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDD 241
            S VP   +       +  +        +D   VP   +D    P   +D    P   +DD
Sbjct: 2553 SVVPVTPAGVPVVPVTPGDGPVVPVTPADSLVVPVTSADSPVFPVTPADSPVFPVSPADD 2612

Query: 242  ---SEAPDDSSDDSEAPDDS-------SDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDD 291
                  P DS     +P DS       +D    P   ++    P  S+D        +D 
Sbjct: 2613 LVVPVTPGDSPVVPVSPADSPVVLVTPADGPVVPVTPANGPVVPVTSADSPFVPVIPADG 2672

Query: 292  SEASDDSSD---------DSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPV-PAED 340
                D S+D         D     D +DD  VP    DD  VP    DD  +PV PA+D
Sbjct: 2673 LVVLDSSTDVLVVPVFPTDGILVPDLADDPVVPVTPGDDPVVPVTPGDDPVIPVTPADD 2731



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 41/148 (27%), Positives = 62/148 (41%), Gaps = 20/148 (13%)

Query: 214  VPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAP---DDSSDDSEAPDD--- 267
            VPD  +D S V + ++D   VP+        P   +D   AP    D  D +  P D   
Sbjct: 3007 VPDPSADSSVVSNPTTDGLIVPNPLLAGPVVPVTPTDGPLAPVILADCPDVTVTPADGPV 3066

Query: 268  ----SSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDD--SEAPDDKSDDSDVPEDKSD- 320
                ++     PD +++    S+ + DD   ++ S+    S  P D +D   +P D  D 
Sbjct: 3067 VCAFTTGGPVFPDPTAEGLVVSNPTVDDPVVTNPSTKGLVSATPADCADVPVIPADCPDV 3126

Query: 321  ------DSDVPDDNSDDLEVPV-PAEDL 341
                  DS VPD  +D   V V P +DL
Sbjct: 3127 LVNLVNDSVVPDFTADWTVVSVSPPDDL 3154



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 33/134 (24%), Positives = 50/134 (37%)

Query: 207  DNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPD 266
            D +DD  V    +D   +P   +D + VP   +D    P  S D    P   ++   AP 
Sbjct: 1579 DLADDPVVSVTIADSPVIPVTPADSTVVPVTLADGPVVPVTSVDIPVVPVTPANGPVAPV 1638

Query: 267  DSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPD 326
               DD     + +D S     S+D        +D    P   +D   VP   +D   V  
Sbjct: 1639 TPVDDPVVSVNPADGSVVPVTSADCPVVPVTPADGLVVPVTPADSPIVPVTPADSPVVLV 1698

Query: 327  DNSDDLEVPVPAED 340
             ++D   +PV   D
Sbjct: 1699 TSADSPVIPVTPAD 1712



 Score = 34.7 bits (78), Expect = 0.30
 Identities = 55/203 (27%), Positives = 74/203 (36%), Gaps = 25/203 (12%)

Query: 163  SDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSD---DNSDDSDVPDDKS 219
            +D   A D ++D    P   +D   VPD   D        DS       +D + VP   +
Sbjct: 1552 ADGLVALDSSTDVLVVPVSPTDGVLVPDLADDPVVSVTIADSPVIPVTPADSTVVPVTLA 1611

Query: 220  DDSDVPDDSSDDSDVPDDSSDDSEAP----DDS------SDDSEAPDDSSDDSEAPDDSS 269
            D   VP  S D   VP   ++   AP    DD       +D S  P  S+D    P   +
Sbjct: 1612 DGPVVPVTSVDIPVVPVTPANGPVAPVTPVDDPVVSVNPADGSVVPVTSADCPVVPVTPA 1671

Query: 270  DDSEAPDDSSD---------DSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSD 320
            D    P   +D         DS     +S DS     +  DS      S D+D P     
Sbjct: 1672 DGLVVPVTPADSPIVPVTPADSPVVLVTSADSPVIPVTPADSPVVPVTSADTDSPGSPVT 1731

Query: 321  DSD---VPDDNSDDLEVPVPAED 340
             +D   VP  ++D L VPV   D
Sbjct: 1732 SADGPVVPVTSADSLPVPVTPAD 1754



 Score = 33.5 bits (75), Expect = 0.68
 Identities = 31/132 (23%), Positives = 46/132 (34%)

Query: 209  SDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDS 268
            +DD  VP   +D   V    +D   VP   +D       S+D    P   +D    P   
Sbjct: 2111 ADDLIVPVTPADSLIVSVTPADSPVVPVTPADSPVISVASADSPVVPVTPADTVVVPVTP 2170

Query: 269  SDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDN 328
            +D    P   ++        +D        +DD   P   +D   VP   + D  VP   
Sbjct: 2171 ADGPVIPVTPAESPAIPVTPADSPVVPVTPADDPVVPVTPADSPIVPVPPASDPVVPVTP 2230

Query: 329  SDDLEVPVPAED 340
            +D    PV + D
Sbjct: 2231 ADTPGSPVASAD 2242


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 95/467 (20%), Positives = 168/467 (35%), Gaps = 76/467 (16%)

Query: 103 DDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDN 162
           DDE P+   +   +  P             G    V +D     E     + ++ A   +
Sbjct: 175 DDEKPDTSLITQGVPTP-------------GPSANVANDAMSILETITSLNQEASAARAS 221

Query: 163 SDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDS 222
           ++ S A        + P   + D+    + + +   D    ++D   +  +      + S
Sbjct: 222 TETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEEFS 281

Query: 223 DVPDDSSDDSDVPDDSSDDSEAPDD-SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDD 281
           D+P    +  +   + ++      D   + SE  + S+D  E   DS++  E   +  + 
Sbjct: 282 DLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEK 341

Query: 282 SEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSD----------------DSDVP 325
           +E   D S  SE +    D+ +A + + +   +P +K+                 DSDV 
Sbjct: 342 TEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKEDFSLIDSDVD 401

Query: 326 ---------------DDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQ-HDSSDD 369
                              +D E  V   D   EG+I SD+EE  +     +Q  DSS+ 
Sbjct: 402 GLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEG 461

Query: 370 AGEQDLGENLSKP--------PSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIV 421
             +      + KP         SD E   E   + +  E+E   +  Q  + K + K   
Sbjct: 462 KTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQ 521

Query: 422 EPPRKRQTKTK-------NIVEPPRKR-QTKTKNIVEPLRKRKAKTKNVSVTPGHKK--- 470
           +  + + +KTK       ++ E   K  + K   I E L++RK   K V+++   KK   
Sbjct: 522 KAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSR 581

Query: 471 --RGPSKKKPGAAKVEKRKTRTPKCKVPGCFLQDLEKSKKYSGKNLK 515
                SKKK    +  K   +T          +  EK K  S K LK
Sbjct: 582 NVEENSKKKQQYEEDSKETLKTS---------EHCEKEKISSSKELK 619



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 91/459 (19%), Positives = 182/459 (39%), Gaps = 41/459 (8%)

Query: 56  SGDTSGSSVARRAPKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPA 115
           S +TS +  + RA K+  S     D+ +D+E  + +    +    +S  E  E       
Sbjct: 221 STETSNAKTSERASKKLPSQPTT-DTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEE 279

Query: 116 IQEPPIVISDDDNDDDNGNDLEV--PDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 173
             + P  + +  N     N+L +   D   + SE  + ++D  E   D+++  E   +  
Sbjct: 280 FSDLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKK 339

Query: 174 DDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSD 233
           + +E   D+S  S+      D+      +  S     + +    K+ +    D S  DSD
Sbjct: 340 EKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKEDFSLIDSD 399

Query: 234 VPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSE 293
           V D  +D + +   +SD S   +D+ ++      +SD  E  + +SDD E +  +   ++
Sbjct: 400 V-DGLTDITVSSVHTSDLSSFEEDTEEEVV----TSDSMEEGEITSDDEEKNKQNKTKTQ 454

Query: 294 ASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEE 353
            SD S   +     KS            S    D+ D+L V    + +  E      EE 
Sbjct: 455 TSDSSEGKT-----KSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKE-----KEER 504

Query: 354 LVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKR 413
           L+     +++    +   ++      SK      ++ ++ E    + E  A  +++  K 
Sbjct: 505 LLRRQ--INREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKE 562

Query: 414 KSKTKTIVEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLR-----KRKAKTKNVSVTPGH 468
           +   +  V   +KR+  ++N+ E  +K+Q   ++  E L+     +++  + +  +   H
Sbjct: 563 RKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVH 622

Query: 469 KKRGPSK-------------KKPGAAKVE---KRKTRTP 491
            K  PSK             +    +K+E   KR+T TP
Sbjct: 623 AKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTP 661



 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 81/398 (20%), Positives = 161/398 (40%), Gaps = 53/398 (13%)

Query: 89   THEEKKAKLLEINSDDESPEC-CHVKPA----IQEPPIVISDDDNDDDNG--NDLEVPDD 141
            + EEK  ++L        PE  C  KP+    +Q  P+++++  N +++G   + E+  +
Sbjct: 2678 SEEEKNGEILA------PPESLCGGKPSGIAELQREPLLVNESLNVENSGFRTNEEIHSE 2731

Query: 142  NSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS-----DDSDVPDDNSD-- 194
            + +  E      D++EA   +S +++  +   ++   P            D PDDN D  
Sbjct: 2732 SYNKGEISSGRKDNAEAISGHSVEADPKEVEEEERHMPKRKRKQHYLSSEDEPDDNPDVL 2791

Query: 195  DSSDDNSD---------DSSDDNSDD-SDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEA 244
            DS  + +          D+ ++NS D  ++P   S+ +       ++ D    S    E 
Sbjct: 2792 DSRIETAQRQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVMEEKDEYSSSETTGEK 2851

Query: 245  PDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDS--EASDDSSDDS 302
            P+ + DD+    +               + P +++   +  DDS  D+     + S   S
Sbjct: 2852 PEQNDDDTIKSQEEDQPIIIKRKRGRPRKYPVETT--LKMKDDSKTDTGIVTVEQSPSSS 2909

Query: 303  EAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVS 362
            +    ++D+S+       +  + +D+ ++  V      +   G+         + +  VS
Sbjct: 2910 KLKVMQTDESNKETANLQERSISNDDGEEKIV----TSVRRRGR-------KPKRSLTVS 2958

Query: 363  QHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRK--SKTKTI 420
              D+     E+   +++S P  D +      E +   E+EP+    +S  R    ++KT 
Sbjct: 2959 D-DAESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSEAQRSKTQ 3017

Query: 421  VEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRKAK 458
            + P  KR    K  V PP  R T+ +  VE    +KAK
Sbjct: 3018 LSPSIKR----KREVSPPGAR-TRGQQRVEEAPVKKAK 3050



 Score = 31.6 bits (70), Expect = 2.6
 Identities = 43/227 (18%), Positives = 79/227 (34%), Gaps = 22/227 (9%)

Query: 159  PDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDK 218
            PD   +  E   +    S+  D   +++ V       SS  +S  +  D+S  + +P  K
Sbjct: 941  PDKEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASSSAHS--TQKDSSHRAKLPLAK 998

Query: 219  SDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDS-SDDSEAPDDSSDDSEAPDD 277
                   D +S   +        S +   SS D +  D++ SDD +  +  S   +A  +
Sbjct: 999  EKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDKDGKEVDSSHEKARGN 1058

Query: 278  SS-------------------DDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDK 318
            SS                    +    ++    +  S  S    + P    D + +PE +
Sbjct: 1059 SSLMEKKLSRRLCENRRGSLSQEMAKGEEKLAANTLSTPSGSSLQRPKKSGDMTLIPEQE 1118

Query: 319  SDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHD 365
              + D      +  EV    ++  N  Q   D E + +  +A  Q D
Sbjct: 1119 PMEIDSEPGVENVFEVSKTQDNRNNNSQQDIDSENMKQKTSATVQKD 1165



 Score = 30.0 bits (66), Expect = 7.5
 Identities = 88/511 (17%), Positives = 177/511 (34%), Gaps = 96/511 (18%)

Query: 91   EEKKAKLLEINSDDESPECCHVKPAIQEPPIVIS----------DDDNDDDNGNDLEVPD 140
            EE   K LE       P+   +K  ++E  ++            D  N ++N    +  +
Sbjct: 542  EESSTKSLE-------PKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYE 594

Query: 141  DNSDDSEAPDDNSDDSEAPDDN--------SDDSEAPDDNSDDSEAPDDNSDDSDVPDDN 192
            ++S ++    ++ +  +             S+ S+     S+     D+N ++S +  ++
Sbjct: 595  EDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREH 654

Query: 193  SDDSSDDNSDDSSDDNSDDSDVPDD-KSDDSDVPDDSSDDSDVPDDS---SDDSEAPDDS 248
               +S     +   + +D  DV    +  +    +     S + ++     DDSE P   
Sbjct: 655  KRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLK 714

Query: 249  SDDSEAPDDSSDDSEAPDDSSDDS---------EAPDDSSDDSEASDDSSD---DSEASD 296
            S   +    S +  E     S+D          +    + D++E          +     
Sbjct: 715  SLLKKEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQK 774

Query: 297  DSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVE 356
             S     + DDK++      ++   S +  D     E  +  ++  N  +  + +E  + 
Sbjct: 775  QSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDE--NVRKENNKKERRLS 832

Query: 357  AAAAVSQHDS---------SDDAGEQDLGENLSK-PPSDPEANPEVSERKLPTEEEPAPV 406
            A    ++H S          D  G +  G  L +   S  E   ++    + +  +P  V
Sbjct: 833  AEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEV 892

Query: 407  VEQSGKRKSKT----KTIVEPPRKRQTKTKNIVEP--------------PRKRQTKTKNI 448
            V +  KR++K+    K +++   K Q K   +VE               P K +   +N 
Sbjct: 893  VHKE-KRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEEND 951

Query: 449  VEPLRKRKAKTKNVSVT-------------------PGHKKRGPSKKKPGAAKVEKRKTR 489
             E  RK K + K    T                     H+ + P  K+   +  +   TR
Sbjct: 952  SEKQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTR 1011

Query: 490  TPKCKVPGCFLQDLEKSKKYSGKNLKRNKDE 520
              +    G       +S K+S K++K+ KDE
Sbjct: 1012 LERKLSDG----HKSRSLKHSSKDIKK-KDE 1037


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 110/508 (21%), Positives = 184/508 (36%), Gaps = 51/508 (10%)

Query: 28  SSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPK---RQASSVVVIDSDSD 84
           SSD  S SS     PK Q   I  V  ++   +    AR APK    +A+S     S S 
Sbjct: 166 SSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSS 225

Query: 85  EECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNSD 144
               + EEK A            +    K  + + P+  +       + ++    D +SD
Sbjct: 226 SSDDSEEEKAAA--------TPKKTVPKKQVVAKAPVKAATTPTRKSSSSE----DSSSD 273

Query: 145 DSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDS 204
           + E       +   P  +     AP         P   + +   P ++S+DSSD+     
Sbjct: 274 EEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDE----- 328

Query: 205 SDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPD----DSSD 260
           SD +S++   P  K+  S             + SSD S++  DSS+D EAP      + +
Sbjct: 329 SDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDS--DSSEDDEAPSKPAGTTKN 386

Query: 261 DSEAP-----DDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVP 315
            S  P       +   + AP       +       DS +S++ S  SE   ++     V 
Sbjct: 387 SSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSE---EEKTKKMVA 443

Query: 316 EDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDL 375
             K   +     +    + P  + D  ++   +S EEE  + + +  +      AG    
Sbjct: 444 TTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAG---- 499

Query: 376 GENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRKRQTKTKNIV 435
           G   SKP S  +   E S      +       E+  K K K       PR +  K     
Sbjct: 500 GAAPSKPASAKKGKAESSNSSSSDDSSE----EEEEKLKGKGS-----PRPQAPKANGTS 550

Query: 436 EPPRKRQTKTKNIVEPLRKRKAKTKNVSVTPGHKKRGPSKKKPGAAKVEKRKTRTPKCKV 495
               +     KN  E   ++K     VS +   KKR   K+   A + E  + +  K + 
Sbjct: 551 ALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKR---KQNEAAKEAETPQAKKIKLQT 607

Query: 496 PGCFLQDLEKSKKYSGKNLKRNKDELVQ 523
           P  F    +K +K +    +R ++E ++
Sbjct: 608 PNTF-PKRKKGEKRASSPFRRVREEEIE 634



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 101/494 (20%), Positives = 167/494 (33%), Gaps = 68/494 (13%)

Query: 64  VARRAPKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVI 123
           VA++A K+ +SS     S+ +EE      KKA +         P     K +        
Sbjct: 74  VAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAV-PAKRVGLPPGKAAAKASESSSSEES 132

Query: 124 SDDDNDDDNGND------------LEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDD 171
           SDDD+++D                 + P   +  S++  D+S + E P +          
Sbjct: 133 SDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTV 192

Query: 172 NSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDD-------------------- 211
            +     P        + +  +  SS  +S  SS D+S++                    
Sbjct: 193 KAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKA 252

Query: 212 ----SDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDD 267
               +  P  KS  S+  D SSD+ +       +   P  S     AP         P  
Sbjct: 253 PVKAATTPTRKSSSSE--DSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPK 310

Query: 268 SSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDD 327
            + + + P +SS+DS    DSS + E    +         K   +    + S DS   D 
Sbjct: 311 KAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDS 370

Query: 328 NSDDLEVPVPAEDLCNEGQ--IASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSD 385
           + DD     PA    N       + +   V+ AAA  Q            G+ L    +D
Sbjct: 371 SEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGG--------GQKLLTRKAD 422

Query: 386 PEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRKRQTKTKNIVEPPRKRQTKT 445
             ++ E S     +EEE    +  + K K+  K  +  P K+         P   R + +
Sbjct: 423 SSSSEEESS---SSEEEKTKKMVATTKPKATAKAALSLPAKQ--------APQGSRDSSS 471

Query: 446 KNIVEPLRKRKAKTKNVSVTPGHKKRGPSKKKPGAAKVEKRKTRTPKCKVPGCFLQD--- 502
            +      + + KT   +V     K+ P K   GAA  +    +  K +       D   
Sbjct: 472 DSDSSSSEEEEEKTSKSAV-----KKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSS 526

Query: 503 LEKSKKYSGKNLKR 516
            E+ +K  GK   R
Sbjct: 527 EEEEEKLKGKGSPR 540



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 99/445 (22%), Positives = 171/445 (38%), Gaps = 52/445 (11%)

Query: 27  SSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQASSVVVIDSDSDEE 86
           SSS  +S SS      K  A+    V  +         A   P R++SS    DS SDEE
Sbjct: 218 SSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSE--DSSSDEE 275

Query: 87  CHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNSDD- 145
               EE+K  +         P      P    PP   S          + + P ++S+D 
Sbjct: 276 ----EEQKKPM------KNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDS 325

Query: 146 SEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSS 205
           S+  D +S++ + P   +  S+A        +A + +SD SD   D+S+D    +    +
Sbjct: 326 SDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSD--SDSSEDDEAPSKPAGT 383

Query: 206 DDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAP 265
             NS +      KS        +   +  P       +       DS + ++ S  SE  
Sbjct: 384 TKNSSNKPAVTTKS-------PAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEE 436

Query: 266 DDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVP 325
                 +     ++  +  S  +    + S DSS DS+     S  S+  E+K+  S V 
Sbjct: 437 KTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSD-----SSSSEEEEEKTSKSAVK 491

Query: 326 DDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSD 385
                      P++        AS ++   E++ + S  DSS++  E+  G+  S  P  
Sbjct: 492 KKPQKVAGGAAPSKP-------ASAKKGKAESSNSSSSDDSSEEEEEKLKGKG-SPRPQA 543

Query: 386 PEAN------------PEVSERKLPTEEEPAPVVEQSG----KRKSKTKTIVEPPRKRQT 429
           P+AN             + SE +   +++ A VV +SG    +++++     E P+ ++ 
Sbjct: 544 PKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKI 603

Query: 430 KTKNIVEPPRKRQTKTKNIVEPLRK 454
           K +     P KR+   K    P R+
Sbjct: 604 KLQTPNTFP-KRKKGEKRASSPFRR 627


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
            theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 82/354 (23%), Positives = 116/354 (32%), Gaps = 27/354 (7%)

Query: 55   RSGDTSGSSVARRAPKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKP 114
            R G  + S   R  P+++       D D     H  +E++ + L    DDE  E      
Sbjct: 900  RKGPEADSEWRRGPPEKEWRRGEGRDEDRS---HRRDEERPRRL---GDDEDRE------ 947

Query: 115  AIQEPPIVISDDDN------DDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEA 168
                 P +  DDD       DDD G      +D      A DD        DD      A
Sbjct: 948  -----PSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIA 1002

Query: 169  PDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDS 228
             +D  +   A DD      + +D     + D          DD       +DD      +
Sbjct: 1003 DEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRN 1062

Query: 229  SDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDS 288
            +DD   P    DD   P    DD   P    DD   P    DD   P    DD      +
Sbjct: 1063 ADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRN 1122

Query: 289  SDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIA 348
            +DD       ++D   P    DD D    ++DD   P    D    P P   L   G   
Sbjct: 1123 ADDDRIPRRGAEDDRGPWRNMDD-DRLSRRADDDRFPRRGDDSR--PGPWRPLVKPGGWR 1179

Query: 349  SDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEE 402
              E+   E+     +   S++  E D  +   +   D E N +  ER+   E +
Sbjct: 1180 EKEKAREESWGPPRESRPSEER-EWDREKERDRDNQDREENDKDPERERDRERD 1232



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 52/229 (22%), Positives = 78/229 (34%), Gaps = 30/229 (13%)

Query: 129  DDDNGNDLEVPDDNS-----DDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 183
            DDD G    + DD       DD   P    DD   P    DD   P    DD   P  N+
Sbjct: 1064 DDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNA 1123

Query: 184  DDSDVPDDNSDDSSD---DNSDDSSDDNSDDSDVPDDKSDDSDVP-------------DD 227
            DD  +P   ++D      +  DD     +DD   P    D    P             + 
Sbjct: 1124 DDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEK 1183

Query: 228  SSDDSDVPDDSSDDSEAPD-DSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASD 286
            + ++S  P   S  SE  + D   + +  +   ++++   +   D E   D  D      
Sbjct: 1184 AREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPR 1243

Query: 287  D--------SSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDD 327
            D        + + S   D S  D    DD+  + D   D  +  D+ DD
Sbjct: 1244 DEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDD 1292



 Score = 29.6 bits (65), Expect = 9.8
 Identities = 39/152 (25%), Positives = 50/152 (32%), Gaps = 20/152 (13%)

Query: 127  DNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD-- 184
            D + +   D +  ++N  D E   D   D     D  D    P D       P + S   
Sbjct: 1204 DREKERDRDNQDREENDKDPERERDRERDV----DREDRFRRPRDEGGWRRGPAEESSSW 1259

Query: 185  -DSDVPDDNSDDSSDDNSDDSSD-----DNSDDSD--VPDDKSDDSDV-----PDDSSDD 231
             DS   DD   D      DD  D     D  DD D   P  +S+  +V      DD  DD
Sbjct: 1260 RDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDD 1319

Query: 232  SDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSE 263
              V +        P   S D E   D   + E
Sbjct: 1320 R-VEERDPPRRVPPPALSRDRERDRDREREGE 1350


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 67/359 (18%), Positives = 145/359 (40%), Gaps = 31/359 (8%)

Query: 106  SPECCHVKPAIQEPPI----VISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDD 161
            S + C ++P +  P       I + +   +   D+ +P++  ++ E   +  +  E  ++
Sbjct: 1183 STQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEE 1242

Query: 162  NSDDSEAPDDN-SDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSD 220
            ++  SE P  + +D S +P+  + + +V ++       +    S ++  +  +   ++ +
Sbjct: 1243 DAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEE 1302

Query: 221  DSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSS- 279
            D+      +DD D  D+  DD         + E      D  E P       +A    S 
Sbjct: 1303 DAAAETAQNDDHDADDE--DDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSR 1360

Query: 280  ---DDSEASDDSSDDSEASDDSSDDSE----APDDKSDDSDVPE---DKSDDSDVPDDNS 329
                D E ++  S++ + S D+S  SE    + DD  +DS   E   +  ++ ++P    
Sbjct: 1361 EKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSEL 1420

Query: 330  DDLEVPVPAEDLCNEGQ-----IASDEEELVEAAAAVSQHDSSDDAGEQDLGENL----- 379
             DLE     + L  E          D EE + A   +  +  +D+  +  + E+      
Sbjct: 1421 -DLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEH 1479

Query: 380  SKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRKRQTKTKNIVEPP 438
            + P S  +++P  S R + +   PA  +E    + S  +  +  P  +  +T  +++ P
Sbjct: 1480 NSPISSVQSHPSQSVRSVSSPNVPA--LESGYTQISPEQGSLSAPSMQNMETSPMMDVP 1536



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 73/340 (21%), Positives = 122/340 (35%), Gaps = 45/340 (13%)

Query: 85   EECHTHEEKKAKLLEINS-----DDESPECCHVKPAIQEP---PIVISDDDNDDDNGNDL 136
            EE    EE+ A   E+ +        SPE    +P ++E    P V  +    ++   +L
Sbjct: 1234 EEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQEL 1293

Query: 137  EVPD-DNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVP------ 189
            E P+ +  +D+ A    +DD +A  D+ DD         + E      D  + P      
Sbjct: 1294 EEPEPEEEEDAAAETAQNDDHDA--DDEDDGHLESTKKKELEEQPTREDVKEEPGVQESF 1351

Query: 190  -DDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDS 248
             D N   S +   D   ++   DS+      D S V +  +   D  ++ S   E   + 
Sbjct: 1352 LDANMQKSREKIKD--KEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIEL 1409

Query: 249  SDDSEAPDDSSD-------DSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSS-- 299
             ++ E P    D        S   ++SS+   A  D  +   A       ++A +D    
Sbjct: 1410 KEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMS 1469

Query: 300  --DDSEAPDDKSDDSDVPEDKS------DDSDVPDDNSDDLEVPVPAEDLCNEGQIASDE 351
              +D  A +  S  S V    S         +VP   S   ++  P +   +   + + E
Sbjct: 1470 MVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQIS-PEQGSLSAPSMQNME 1528

Query: 352  EELVEAAAAVSQHDSS-DDAGEQDLG------ENLSKPPS 384
               +    +VS H     D+G  DLG      EN   P S
Sbjct: 1529 TSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSS 1568


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 67/359 (18%), Positives = 145/359 (40%), Gaps = 31/359 (8%)

Query: 106  SPECCHVKPAIQEPPI----VISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDD 161
            S + C ++P +  P       I + +   +   D+ +P++  ++ E   +  +  E  ++
Sbjct: 1183 STQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEE 1242

Query: 162  NSDDSEAPDDN-SDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSD 220
            ++  SE P  + +D S +P+  + + +V ++       +    S ++  +  +   ++ +
Sbjct: 1243 DAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEE 1302

Query: 221  DSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSS- 279
            D+      +DD D  D+  DD         + E      D  E P       +A    S 
Sbjct: 1303 DAAAETAQNDDHDADDE--DDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSR 1360

Query: 280  ---DDSEASDDSSDDSEASDDSSDDSE----APDDKSDDSDVPE---DKSDDSDVPDDNS 329
                D E ++  S++ + S D+S  SE    + DD  +DS   E   +  ++ ++P    
Sbjct: 1361 EKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSEL 1420

Query: 330  DDLEVPVPAEDLCNEGQ-----IASDEEELVEAAAAVSQHDSSDDAGEQDLGENL----- 379
             DLE     + L  E          D EE + A   +  +  +D+  +  + E+      
Sbjct: 1421 -DLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEH 1479

Query: 380  SKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRKRQTKTKNIVEPP 438
            + P S  +++P  S R + +   PA  +E    + S  +  +  P  +  +T  +++ P
Sbjct: 1480 NSPISSVQSHPSQSVRSVSSPNVPA--LESGYTQISPEQGSLSAPSMQNMETSPMMDVP 1536



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 73/340 (21%), Positives = 122/340 (35%), Gaps = 45/340 (13%)

Query: 85   EECHTHEEKKAKLLEINS-----DDESPECCHVKPAIQEP---PIVISDDDNDDDNGNDL 136
            EE    EE+ A   E+ +        SPE    +P ++E    P V  +    ++   +L
Sbjct: 1234 EEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQEL 1293

Query: 137  EVPD-DNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVP------ 189
            E P+ +  +D+ A    +DD +A  D+ DD         + E      D  + P      
Sbjct: 1294 EEPEPEEEEDAAAETAQNDDHDA--DDEDDGHLESTKKKELEEQPTREDVKEEPGVQESF 1351

Query: 190  -DDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDS 248
             D N   S +   D   ++   DS+      D S V +  +   D  ++ S   E   + 
Sbjct: 1352 LDANMQKSREKIKD--KEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIEL 1409

Query: 249  SDDSEAPDDSSD-------DSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSS-- 299
             ++ E P    D        S   ++SS+   A  D  +   A       ++A +D    
Sbjct: 1410 KEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMS 1469

Query: 300  --DDSEAPDDKSDDSDVPEDKS------DDSDVPDDNSDDLEVPVPAEDLCNEGQIASDE 351
              +D  A +  S  S V    S         +VP   S   ++  P +   +   + + E
Sbjct: 1470 MVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQIS-PEQGSLSAPSMQNME 1528

Query: 352  EELVEAAAAVSQHDSS-DDAGEQDLG------ENLSKPPS 384
               +    +VS H     D+G  DLG      EN   P S
Sbjct: 1529 TSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSS 1568


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 67/359 (18%), Positives = 145/359 (40%), Gaps = 31/359 (8%)

Query: 106  SPECCHVKPAIQEPPI----VISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDD 161
            S + C ++P +  P       I + +   +   D+ +P++  ++ E   +  +  E  ++
Sbjct: 1183 STQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEE 1242

Query: 162  NSDDSEAPDDN-SDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSD 220
            ++  SE P  + +D S +P+  + + +V ++       +    S ++  +  +   ++ +
Sbjct: 1243 DAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEE 1302

Query: 221  DSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSS- 279
            D+      +DD D  D+  DD         + E      D  E P       +A    S 
Sbjct: 1303 DAAAETAQNDDHDADDE--DDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSR 1360

Query: 280  ---DDSEASDDSSDDSEASDDSSDDSE----APDDKSDDSDVPE---DKSDDSDVPDDNS 329
                D E ++  S++ + S D+S  SE    + DD  +DS   E   +  ++ ++P    
Sbjct: 1361 EKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSEL 1420

Query: 330  DDLEVPVPAEDLCNEGQ-----IASDEEELVEAAAAVSQHDSSDDAGEQDLGENL----- 379
             DLE     + L  E          D EE + A   +  +  +D+  +  + E+      
Sbjct: 1421 -DLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEH 1479

Query: 380  SKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRKRQTKTKNIVEPP 438
            + P S  +++P  S R + +   PA  +E    + S  +  +  P  +  +T  +++ P
Sbjct: 1480 NSPISSVQSHPSQSVRSVSSPNVPA--LESGYTQISPEQGSLSAPSMQNMETSPMMDVP 1536



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 73/340 (21%), Positives = 122/340 (35%), Gaps = 45/340 (13%)

Query: 85   EECHTHEEKKAKLLEINS-----DDESPECCHVKPAIQEP---PIVISDDDNDDDNGNDL 136
            EE    EE+ A   E+ +        SPE    +P ++E    P V  +    ++   +L
Sbjct: 1234 EEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQEL 1293

Query: 137  EVPD-DNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVP------ 189
            E P+ +  +D+ A    +DD +A  D+ DD         + E      D  + P      
Sbjct: 1294 EEPEPEEEEDAAAETAQNDDHDA--DDEDDGHLESTKKKELEEQPTREDVKEEPGVQESF 1351

Query: 190  -DDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDS 248
             D N   S +   D   ++   DS+      D S V +  +   D  ++ S   E   + 
Sbjct: 1352 LDANMQKSREKIKD--KEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIEL 1409

Query: 249  SDDSEAPDDSSD-------DSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSS-- 299
             ++ E P    D        S   ++SS+   A  D  +   A       ++A +D    
Sbjct: 1410 KEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMS 1469

Query: 300  --DDSEAPDDKSDDSDVPEDKS------DDSDVPDDNSDDLEVPVPAEDLCNEGQIASDE 351
              +D  A +  S  S V    S         +VP   S   ++  P +   +   + + E
Sbjct: 1470 MVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQIS-PEQGSLSAPSMQNME 1528

Query: 352  EELVEAAAAVSQHDSS-DDAGEQDLG------ENLSKPPS 384
               +    +VS H     D+G  DLG      EN   P S
Sbjct: 1529 TSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSS 1568


>gi|40217843 cartilage oligomeric matrix protein precursor [Homo
           sapiens]
          Length = 757

 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 60/227 (26%), Positives = 85/227 (37%), Gaps = 13/227 (5%)

Query: 126 DDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDD 185
           +D D D   D   PD + D      DN      PD  + D +   D  D+  +   N D 
Sbjct: 301 EDVDRDGIGDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRS-QKNDDQ 359

Query: 186 SDVPDDNSDDSSDDNSDDSSDDNSDDS--DVPDDKSDDSDVPDDSSDDSDVPDDSSDDSE 243
            D   D   D+ DD+ D     N  D+   VP+    DSD         + P  S+ D  
Sbjct: 360 KDTDQDGRGDACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGIGDACDNCPQKSNPDQA 419

Query: 244 APDDSSDDSEAPDDSSDDSEAPDDSSDD-SEAPDDSSDDSEASDDSSDDSEASDDSSDDS 302
             D          D   D +   DS D+    P+ + +DS    D     +A DD  D+ 
Sbjct: 420 DVDHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDS----DHDGQGDACDDDDDND 475

Query: 303 EAPDDKSDDSDVPEDKSDDSD---VPDDNSDDLEVP--VPAEDLCNE 344
             PD + +   VP    +D+D   V D   DD +    V   D+C E
Sbjct: 476 GVPDSRDNCRLVPNPGQEDADRDGVGDVCQDDFDADKVVDKIDVCPE 522



 Score = 69.7 bits (169), Expect = 9e-12
 Identities = 58/262 (22%), Positives = 96/262 (36%), Gaps = 8/262 (3%)

Query: 134 NDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNS 193
           N + VP+   +D +   D   D+  PD + D      DN      PD  + D D   D  
Sbjct: 291 NCVTVPNSGQEDVDR--DGIGDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDAC 348

Query: 194 DDSSDDNSDDSSDDNSDD-SDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDS 252
           D+     +DD  D + D   D  DD  D   + + + +   VP+    DS+         
Sbjct: 349 DNCRSQKNDDQKDTDQDGRGDACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGIGDACD 408

Query: 253 EAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDS 312
             P  S+ D    D          D   D +   DS D+     +S+ +    D + D  
Sbjct: 409 NCPQKSNPDQADVDHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDAC 468

Query: 313 DVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGE 372
           D   D  D+  VPD   +   VP P ++  +   +    ++  +A   V + D   +  E
Sbjct: 469 D---DDDDNDGVPDSRDNCRLVPNPGQEDADRDGVGDVCQDDFDADKVVDKIDVCPENAE 525

Query: 373 QDLGE--NLSKPPSDPEANPEV 392
             L +         DPE + ++
Sbjct: 526 VTLTDFRAFQTVVLDPEGDAQI 547



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 48/188 (25%), Positives = 74/188 (39%), Gaps = 19/188 (10%)

Query: 120 PIVISDDDNDDDN---GNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDS 176
           P+V + D  + D    G+  +      +D +   D     +A DD+ D     +   +  
Sbjct: 329 PLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRGDACDDDIDGDRIRNQADNCP 388

Query: 177 EAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSD-DSDVPDDKSD-DSDVPDDSSDDS-- 232
             P  NSD  D   D   D+ D+    S+ D +D D D   D  D D D   D   DS  
Sbjct: 389 RVP--NSDQKDSDGDGIGDACDNCPQKSNPDQADVDHDFVGDACDSDQDQDGDGHQDSRD 446

Query: 233 ---DVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSE---ASD 286
               VP+ + +DS    D     +A DD  D+   PD   +    P+   +D++     D
Sbjct: 447 NCPTVPNSAQEDS----DHDGQGDACDDDDDNDGVPDSRDNCRLVPNPGQEDADRDGVGD 502

Query: 287 DSSDDSEA 294
              DD +A
Sbjct: 503 VCQDDFDA 510



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 53/209 (25%), Positives = 77/209 (36%), Gaps = 24/209 (11%)

Query: 191 DNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDV--PDDSSDDSEAPDDS 248
           DN     +   +D   D   D+  PD  +D   VP++  +   V  PD  + D +   D+
Sbjct: 290 DNCVTVPNSGQEDVDRDGIGDACDPD--ADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDA 347

Query: 249 SDD--SEAPDDSSD-DSEAPDDSSDDSEAPD------DSSDDSEASDDSSDDSEASDDSS 299
            D+  S+  DD  D D +   D+ DD    D      D+      SD    D +   D+ 
Sbjct: 348 CDNCRSQKNDDQKDTDQDGRGDACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGIGDAC 407

Query: 300 DD---SEAPDDKSDDSDVPEDKSD-DSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELV 355
           D+      PD    D D   D  D D D   D   D     P   + N  Q  SD +   
Sbjct: 408 DNCPQKSNPDQADVDHDFVGDACDSDQDQDGDGHQDSRDNCPT--VPNSAQEDSDHDGQG 465

Query: 356 EAAAAVSQHDSSDDAGEQDLGENLSKPPS 384
           +A       D  D+ G  D  +N    P+
Sbjct: 466 DAC-----DDDDDNDGVPDSRDNCRLVPN 489



 Score = 38.5 bits (88), Expect = 0.021
 Identities = 40/181 (22%), Positives = 62/181 (34%), Gaps = 10/181 (5%)

Query: 211 DSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSD 270
           D+ V    S   DV  D   D+  PD   D      D+      PD  + D +   D+ D
Sbjct: 290 DNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACD 349

Query: 271 DSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSD 330
           +  +     +D +   D     +A DD  D     +   +   VP     DSD   D   
Sbjct: 350 NCRS---QKNDDQKDTDQDGRGDACDDDIDGDRIRNQADNCPRVPNSDQKDSD--GDGIG 404

Query: 331 DLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANP 390
           D     P +   N  Q   D + + +A          D  G QD  +N    P+  + + 
Sbjct: 405 DACDNCPQKS--NPDQADVDHDFVGDAC---DSDQDQDGDGHQDSRDNCPTVPNSAQEDS 459

Query: 391 E 391
           +
Sbjct: 460 D 460



 Score = 38.1 bits (87), Expect = 0.027
 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 9/93 (9%)

Query: 124 SDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 183
           SD D D D        D   +    P+   +DS    D+    +A DD+ D+   PD   
Sbjct: 432 SDQDQDGDGHQ-----DSRDNCPTVPNSAQEDS----DHDGQGDACDDDDDNDGVPDSRD 482

Query: 184 DDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPD 216
           +   VP+   +D+  D   D   D+ D   V D
Sbjct: 483 NCRLVPNPGQEDADRDGVGDVCQDDFDADKVVD 515



 Score = 29.6 bits (65), Expect = 9.8
 Identities = 31/123 (25%), Positives = 48/123 (39%), Gaps = 26/123 (21%)

Query: 80  DSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVP 139
           DSD D++   H+            D    C  V  + QE        D+D D   D    
Sbjct: 431 DSDQDQDGDGHQ------------DSRDNCPTVPNSAQE--------DSDHDGQGD--AC 468

Query: 140 DDNSDDSEAPDDNSDDSEAPDDNSDDSE---APDDNSDDSEAPDDNSDDSDVPDDNSDDS 196
           DD+ D+   PD   +    P+   +D++     D   DD +A D   D  DV  +N++ +
Sbjct: 469 DDDDDNDGVPDSRDNCRLVPNPGQEDADRDGVGDVCQDDFDA-DKVVDKIDVCPENAEVT 527

Query: 197 SDD 199
             D
Sbjct: 528 LTD 530


>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
          Length = 686

 Score = 69.7 bits (169), Expect = 9e-12
 Identities = 68/286 (23%), Positives = 121/286 (42%), Gaps = 13/286 (4%)

Query: 103 DDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDN 162
           D  +PE    + A Q P +       +  +  D E P  ++ ++E P  +S ++E    +
Sbjct: 131 DSAAPE--RQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGD 188

Query: 163 SDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSD--DNSDDSSDDNSDDSDVPDDKSD 220
           S D+E P  +S D+E P  ++  ++ P  +S D+     +S D+     D  D      D
Sbjct: 189 SVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGD 248

Query: 221 DSDVPDDSSD--DSDVPDDSSDDSEAPDDSSDDSEAPDDSSDD-SEAPDDSSDDSEAPDD 277
             +  D + D  ++ VP   S ++E P   S D+E P   +   S  P  S D S +P  
Sbjct: 249 SVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQA 308

Query: 278 SSDDSEASDDSS-DDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPV 336
            + +  A + +     E + D+++++E P  K  +   P D    +D  +D   D     
Sbjct: 309 EAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDAR--ADAGEDRVGDGPQQE 366

Query: 337 PAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKP 382
           P ED   E +     E   E  AA  + +S D +   +     ++P
Sbjct: 367 PGED---EERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEP 409



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 67/271 (24%), Positives = 107/271 (39%), Gaps = 41/271 (15%)

Query: 174 DDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSD 233
           +DS AP+   +    P+     +S +  D      S D++ P   + +++ P   S +++
Sbjct: 130 EDSAAPERQEEAEQRPEVPEGSASGEAGD------SVDAEGPLGDNIEAEGPAGDSVEAE 183

Query: 234 VPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSE 293
                S D+E P   S D+E P   +  +E P   S D+E     S D+E     S D+E
Sbjct: 184 GRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAE 243

Query: 294 ASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPV-PAEDLCNEGQIASD-- 350
                S ++  P     ++ VP   S +++ P  +S D E P   A  +  E Q + D  
Sbjct: 244 GRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGS 303

Query: 351 ---EEELVEAAAAVS----------------------------QHDSSDDAGEQDLGENL 379
              + E +E AA  S                              D+  DAGE  +G+  
Sbjct: 304 LSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGP 363

Query: 380 SKPPSDPEANPEVSERKLPTEEEPAPVVEQS 410
            + P + E   E S    P EEE A   E+S
Sbjct: 364 QQEPGEDEERRERSPEG-PREEEAAGGEEES 393



 Score = 29.6 bits (65), Expect = 9.8
 Identities = 32/173 (18%), Positives = 65/173 (37%), Gaps = 25/173 (14%)

Query: 227 DSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASD 286
           ++++   V        E P   ++    P  +  ++E P+ S    EAP  ++   EA  
Sbjct: 3   EAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGG 62

Query: 287 DSSD-----DSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDL 341
              D     ++  +  +  ++EA +   + ++VP+   + S      +  +E   P    
Sbjct: 63  GGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETS-----GAQQVEGASPGRGA 117

Query: 342 CN----------EGQIASDEEELVEAAAAVSQHDSSDDAG-----EQDLGENL 379
                       E   A + +E  E    V +  +S +AG     E  LG+N+
Sbjct: 118 QGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNI 170


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 38/103 (36%), Positives = 54/103 (52%), Gaps = 4/103 (3%)

Query: 196 SSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAP 255
           SS       S+   DD +  DD+ +D +  DD + DS   +D  D SE+   S D+SE  
Sbjct: 629 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSS--EDGGDSSES--SSEDESEDG 684

Query: 256 DDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDS 298
           D++ +D E  DD  DD E  D+ S+ S +S  SS DS  SD +
Sbjct: 685 DENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 31/89 (34%), Positives = 52/89 (58%), Gaps = 2/89 (2%)

Query: 156 SEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVP 215
           SE+ +D+ +D +  D++ D+ E  D+N D S+   D+S+ SS+D S+D  ++  DD D  
Sbjct: 638 SESEEDDEEDED--DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 695

Query: 216 DDKSDDSDVPDDSSDDSDVPDDSSDDSEA 244
           DD+ DD D  ++S   S     S D S++
Sbjct: 696 DDEDDDEDEDNESEGSSSSSSSSGDSSDS 724



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 31/101 (30%), Positives = 49/101 (48%)

Query: 142 NSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNS 201
           N   S     +  +SE  D+  +D E  D+  +D E  D + D  D  + +S+D S+D  
Sbjct: 626 NPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGD 685

Query: 202 DDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDS 242
           ++  DD  +D D  DD+ +D++    SS  S   D S  DS
Sbjct: 686 ENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 5/107 (4%)

Query: 182 NSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDD 241
           N   S     +  +S +D+ +D  D++ D+ +  D+  D S+   DSS+ S     S D+
Sbjct: 626 NPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-----SEDE 680

Query: 242 SEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDS 288
           SE  D++ +D E  DD  DD E  D+ S+ S +   SS DS  SD +
Sbjct: 681 SEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 32/93 (34%), Positives = 47/93 (50%), Gaps = 5/93 (5%)

Query: 170 DDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSS 229
           +   DD E  DD  +D +  DD + DSS+D  D S   + D+S+  D+  +D     D  
Sbjct: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEED-----DED 693

Query: 230 DDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDS 262
           +D D  DD  +D+E+   SS  S + D S  DS
Sbjct: 694 EDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 33/92 (35%), Positives = 48/92 (52%), Gaps = 1/92 (1%)

Query: 238 SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDD-SEASDDSSDDSEASD 296
           S  +SE  D+  +D E  D+  +D E  D S D  ++ + SS+D SE  D++ +D E  D
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 695

Query: 297 DSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDN 328
           D  DD E  D++S+ S      S DS   D N
Sbjct: 696 DDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 33/90 (36%), Positives = 49/90 (54%), Gaps = 5/90 (5%)

Query: 217 DKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPD 276
           ++ D+ D  D+  D+ +  D++ D SE   DSS+ S     S D+SE  D++ +D E  D
Sbjct: 641 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-----SEDESEDGDENEEDDEDED 695

Query: 277 DSSDDSEASDDSSDDSEASDDSSDDSEAPD 306
           D  DD E  D+ S+ S +S  SS DS   D
Sbjct: 696 DDEDDDEDEDNESEGSSSSSSSSGDSSDSD 725



 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 32/107 (29%), Positives = 53/107 (49%), Gaps = 5/107 (4%)

Query: 172 NSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDD 231
           N   S     +  +S+  D+  +D  D++ ++  D+N D S+   D S+ S     S D+
Sbjct: 626 NPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-----SEDE 680

Query: 232 SDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDS 278
           S+  D++ +D E  DD  DD E  D+ S+ S +   SS DS   D +
Sbjct: 681 SEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 29/90 (32%), Positives = 44/90 (48%), Gaps = 4/90 (4%)

Query: 124 SDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 183
           S+ + DD+   D    D++ D+ E  D+N D SE   D+S+ S   +    D    DD  
Sbjct: 638 SESEEDDEEDED----DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 693

Query: 184 DDSDVPDDNSDDSSDDNSDDSSDDNSDDSD 213
           +D D  DD  +D+  + S  SS  + D SD
Sbjct: 694 EDDDEDDDEDEDNESEGSSSSSSSSGDSSD 723



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 32/89 (35%), Positives = 51/89 (57%), Gaps = 6/89 (6%)

Query: 125 DDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD 184
           ++D DD++ ++ E  D+N D SE   D+S+ S     + D+SE  D+N +D E  DD+ D
Sbjct: 645 EEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-----SEDESEDGDENEEDDEDEDDDED 699

Query: 185 DSDVPDDNSDDSSDDNSDDSSDDNSDDSD 213
           D D  +DN  + S  +S  S D +  DS+
Sbjct: 700 D-DEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 3/99 (3%)

Query: 215 PDDKSDDSDVPDDSS---DDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDD 271
           P+ KS  + +   S    DD +  DD  +D E  DD + DS      S +S + D+S D 
Sbjct: 625 PNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDG 684

Query: 272 SEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSD 310
            E  +D  D+ +  DD  D+   S+ SS  S +  D SD
Sbjct: 685 DENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSD 723



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 28/89 (31%), Positives = 44/89 (49%)

Query: 150 DDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNS 209
           +   DD E  DD  +D E  DD + DS     +S +S   D++ D   ++  D+  DD+ 
Sbjct: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 698

Query: 210 DDSDVPDDKSDDSDVPDDSSDDSDVPDDS 238
           DD +  D++S+ S     SS DS   D +
Sbjct: 699 DDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 25/92 (27%), Positives = 45/92 (48%)

Query: 142 NSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNS 201
           +  +SE  D+  +D E  D+  +D E  D + D  ++ + +S+D     D +++  +D  
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 695

Query: 202 DDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSD 233
           DD  DD  +D++     S  S   D S  DS+
Sbjct: 696 DDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 28/85 (32%), Positives = 40/85 (47%)

Query: 246 DDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAP 305
           +   DD E  DD  +D E  DD + DS      S +S + D+S D  E  +D  D+ +  
Sbjct: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 698

Query: 306 DDKSDDSDVPEDKSDDSDVPDDNSD 330
           DD  D+ +  E  S  S    D+SD
Sbjct: 699 DDDEDEDNESEGSSSSSSSSGDSSD 723



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 29/85 (34%), Positives = 47/85 (55%), Gaps = 1/85 (1%)

Query: 248 SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDD-SEASDDSSDDSEAPD 306
           S  +SE  D+  +D E  D+  +D E  D S D  ++S+ SS+D SE  D++ +D E  D
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 695

Query: 307 DKSDDSDVPEDKSDDSDVPDDNSDD 331
           D  DD +  +++S+ S     +S D
Sbjct: 696 DDEDDDEDEDNESEGSSSSSSSSGD 720



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 7/93 (7%)

Query: 124 SDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 183
           S++D+++D        DD  +D E  DD + DS     +S +S + D++ D  E  +D+ 
Sbjct: 640 SEEDDEEDE-------DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDE 692

Query: 184 DDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPD 216
           D+ D  DD+ D+ ++     SS  +S DS   D
Sbjct: 693 DEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 725



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 13/103 (12%)

Query: 272 SEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDD 331
           S++  +  D+ +  D+  D+ E  D++ D SE   D S+ S   ED+S+D    D+N +D
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSS--EDESEDG---DENEED 690

Query: 332 LEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQD 374
            E     ED         DE+E  E+  + S   SS D+ + D
Sbjct: 691 DEDEDDDED--------DDEDEDNESEGSSSSSSSSGDSSDSD 725



 Score = 36.6 bits (83), Expect = 0.080
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 5/91 (5%)

Query: 82  DSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDD 141
           + DEE    E++  +  +  + D S +      +  E      D++ +DD     E  DD
Sbjct: 642 EDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDD-----EDEDD 696

Query: 142 NSDDSEAPDDNSDDSEAPDDNSDDSEAPDDN 172
           + DD E  D+ S+ S +   +S DS   D N
Sbjct: 697 DEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 38/103 (36%), Positives = 54/103 (52%), Gaps = 4/103 (3%)

Query: 196 SSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAP 255
           SS       S+   DD +  DD+ +D +  DD + DS   +D  D SE+   S D+SE  
Sbjct: 629 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSS--EDGGDSSES--SSEDESEDG 684

Query: 256 DDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDS 298
           D++ +D E  DD  DD E  D+ S+ S +S  SS DS  SD +
Sbjct: 685 DENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 31/89 (34%), Positives = 52/89 (58%), Gaps = 2/89 (2%)

Query: 156 SEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVP 215
           SE+ +D+ +D +  D++ D+ E  D+N D S+   D+S+ SS+D S+D  ++  DD D  
Sbjct: 638 SESEEDDEEDED--DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 695

Query: 216 DDKSDDSDVPDDSSDDSDVPDDSSDDSEA 244
           DD+ DD D  ++S   S     S D S++
Sbjct: 696 DDEDDDEDEDNESEGSSSSSSSSGDSSDS 724



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 31/101 (30%), Positives = 49/101 (48%)

Query: 142 NSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNS 201
           N   S     +  +SE  D+  +D E  D+  +D E  D + D  D  + +S+D S+D  
Sbjct: 626 NPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGD 685

Query: 202 DDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDS 242
           ++  DD  +D D  DD+ +D++    SS  S   D S  DS
Sbjct: 686 ENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 5/107 (4%)

Query: 182 NSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDD 241
           N   S     +  +S +D+ +D  D++ D+ +  D+  D S+   DSS+ S     S D+
Sbjct: 626 NPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-----SEDE 680

Query: 242 SEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDS 288
           SE  D++ +D E  DD  DD E  D+ S+ S +   SS DS  SD +
Sbjct: 681 SEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 32/93 (34%), Positives = 47/93 (50%), Gaps = 5/93 (5%)

Query: 170 DDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSS 229
           +   DD E  DD  +D +  DD + DSS+D  D S   + D+S+  D+  +D     D  
Sbjct: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEED-----DED 693

Query: 230 DDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDS 262
           +D D  DD  +D+E+   SS  S + D S  DS
Sbjct: 694 EDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 33/92 (35%), Positives = 48/92 (52%), Gaps = 1/92 (1%)

Query: 238 SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDD-SEASDDSSDDSEASD 296
           S  +SE  D+  +D E  D+  +D E  D S D  ++ + SS+D SE  D++ +D E  D
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 695

Query: 297 DSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDN 328
           D  DD E  D++S+ S      S DS   D N
Sbjct: 696 DDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 33/90 (36%), Positives = 49/90 (54%), Gaps = 5/90 (5%)

Query: 217 DKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPD 276
           ++ D+ D  D+  D+ +  D++ D SE   DSS+ S     S D+SE  D++ +D E  D
Sbjct: 641 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-----SEDESEDGDENEEDDEDED 695

Query: 277 DSSDDSEASDDSSDDSEASDDSSDDSEAPD 306
           D  DD E  D+ S+ S +S  SS DS   D
Sbjct: 696 DDEDDDEDEDNESEGSSSSSSSSGDSSDSD 725



 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 32/107 (29%), Positives = 53/107 (49%), Gaps = 5/107 (4%)

Query: 172 NSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDD 231
           N   S     +  +S+  D+  +D  D++ ++  D+N D S+   D S+ S     S D+
Sbjct: 626 NPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-----SEDE 680

Query: 232 SDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDS 278
           S+  D++ +D E  DD  DD E  D+ S+ S +   SS DS   D +
Sbjct: 681 SEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 29/90 (32%), Positives = 44/90 (48%), Gaps = 4/90 (4%)

Query: 124 SDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 183
           S+ + DD+   D    D++ D+ E  D+N D SE   D+S+ S   +    D    DD  
Sbjct: 638 SESEEDDEEDED----DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 693

Query: 184 DDSDVPDDNSDDSSDDNSDDSSDDNSDDSD 213
           +D D  DD  +D+  + S  SS  + D SD
Sbjct: 694 EDDDEDDDEDEDNESEGSSSSSSSSGDSSD 723



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 32/89 (35%), Positives = 51/89 (57%), Gaps = 6/89 (6%)

Query: 125 DDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD 184
           ++D DD++ ++ E  D+N D SE   D+S+ S     + D+SE  D+N +D E  DD+ D
Sbjct: 645 EEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-----SEDESEDGDENEEDDEDEDDDED 699

Query: 185 DSDVPDDNSDDSSDDNSDDSSDDNSDDSD 213
           D D  +DN  + S  +S  S D +  DS+
Sbjct: 700 D-DEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 3/99 (3%)

Query: 215 PDDKSDDSDVPDDSS---DDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDD 271
           P+ KS  + +   S    DD +  DD  +D E  DD + DS      S +S + D+S D 
Sbjct: 625 PNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDG 684

Query: 272 SEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSD 310
            E  +D  D+ +  DD  D+   S+ SS  S +  D SD
Sbjct: 685 DENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSD 723



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 28/89 (31%), Positives = 44/89 (49%)

Query: 150 DDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNS 209
           +   DD E  DD  +D E  DD + DS     +S +S   D++ D   ++  D+  DD+ 
Sbjct: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 698

Query: 210 DDSDVPDDKSDDSDVPDDSSDDSDVPDDS 238
           DD +  D++S+ S     SS DS   D +
Sbjct: 699 DDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 25/92 (27%), Positives = 45/92 (48%)

Query: 142 NSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNS 201
           +  +SE  D+  +D E  D+  +D E  D + D  ++ + +S+D     D +++  +D  
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 695

Query: 202 DDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSD 233
           DD  DD  +D++     S  S   D S  DS+
Sbjct: 696 DDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 28/85 (32%), Positives = 40/85 (47%)

Query: 246 DDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAP 305
           +   DD E  DD  +D E  DD + DS      S +S + D+S D  E  +D  D+ +  
Sbjct: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 698

Query: 306 DDKSDDSDVPEDKSDDSDVPDDNSD 330
           DD  D+ +  E  S  S    D+SD
Sbjct: 699 DDDEDEDNESEGSSSSSSSSGDSSD 723



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 29/85 (34%), Positives = 47/85 (55%), Gaps = 1/85 (1%)

Query: 248 SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDD-SEASDDSSDDSEAPD 306
           S  +SE  D+  +D E  D+  +D E  D S D  ++S+ SS+D SE  D++ +D E  D
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 695

Query: 307 DKSDDSDVPEDKSDDSDVPDDNSDD 331
           D  DD +  +++S+ S     +S D
Sbjct: 696 DDEDDDEDEDNESEGSSSSSSSSGD 720



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 7/93 (7%)

Query: 124 SDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 183
           S++D+++D        DD  +D E  DD + DS     +S +S + D++ D  E  +D+ 
Sbjct: 640 SEEDDEEDE-------DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDE 692

Query: 184 DDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPD 216
           D+ D  DD+ D+ ++     SS  +S DS   D
Sbjct: 693 DEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 725



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 13/103 (12%)

Query: 272 SEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDD 331
           S++  +  D+ +  D+  D+ E  D++ D SE   D S+ S   ED+S+D    D+N +D
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSS--EDESEDG---DENEED 690

Query: 332 LEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQD 374
            E     ED         DE+E  E+  + S   SS D+ + D
Sbjct: 691 DEDEDDDED--------DDEDEDNESEGSSSSSSSSGDSSDSD 725



 Score = 36.6 bits (83), Expect = 0.080
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 5/91 (5%)

Query: 82  DSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDD 141
           + DEE    E++  +  +  + D S +      +  E      D++ +DD     E  DD
Sbjct: 642 EDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDD-----EDEDD 696

Query: 142 NSDDSEAPDDNSDDSEAPDDNSDDSEAPDDN 172
           + DD E  D+ S+ S +   +S DS   D N
Sbjct: 697 DEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 38/103 (36%), Positives = 54/103 (52%), Gaps = 4/103 (3%)

Query: 196 SSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAP 255
           SS       S+   DD +  DD+ +D +  DD + DS   +D  D SE+   S D+SE  
Sbjct: 666 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSS--EDGGDSSES--SSEDESEDG 721

Query: 256 DDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDS 298
           D++ +D E  DD  DD E  D+ S+ S +S  SS DS  SD +
Sbjct: 722 DENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 31/89 (34%), Positives = 52/89 (58%), Gaps = 2/89 (2%)

Query: 156 SEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVP 215
           SE+ +D+ +D +  D++ D+ E  D+N D S+   D+S+ SS+D S+D  ++  DD D  
Sbjct: 675 SESEEDDEEDED--DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 732

Query: 216 DDKSDDSDVPDDSSDDSDVPDDSSDDSEA 244
           DD+ DD D  ++S   S     S D S++
Sbjct: 733 DDEDDDEDEDNESEGSSSSSSSSGDSSDS 761



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 31/101 (30%), Positives = 49/101 (48%)

Query: 142 NSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNS 201
           N   S     +  +SE  D+  +D E  D+  +D E  D + D  D  + +S+D S+D  
Sbjct: 663 NPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGD 722

Query: 202 DDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDS 242
           ++  DD  +D D  DD+ +D++    SS  S   D S  DS
Sbjct: 723 ENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 763



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 5/107 (4%)

Query: 182 NSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDD 241
           N   S     +  +S +D+ +D  D++ D+ +  D+  D S+   DSS+ S     S D+
Sbjct: 663 NPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-----SEDE 717

Query: 242 SEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDS 288
           SE  D++ +D E  DD  DD E  D+ S+ S +   SS DS  SD +
Sbjct: 718 SEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 32/93 (34%), Positives = 47/93 (50%), Gaps = 5/93 (5%)

Query: 170 DDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSS 229
           +   DD E  DD  +D +  DD + DSS+D  D S   + D+S+  D+  +D     D  
Sbjct: 676 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEED-----DED 730

Query: 230 DDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDS 262
           +D D  DD  +D+E+   SS  S + D S  DS
Sbjct: 731 EDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 763



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 33/92 (35%), Positives = 48/92 (52%), Gaps = 1/92 (1%)

Query: 238 SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDD-SEASDDSSDDSEASD 296
           S  +SE  D+  +D E  D+  +D E  D S D  ++ + SS+D SE  D++ +D E  D
Sbjct: 673 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 732

Query: 297 DSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDN 328
           D  DD E  D++S+ S      S DS   D N
Sbjct: 733 DDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 33/90 (36%), Positives = 49/90 (54%), Gaps = 5/90 (5%)

Query: 217 DKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPD 276
           ++ D+ D  D+  D+ +  D++ D SE   DSS+ S     S D+SE  D++ +D E  D
Sbjct: 678 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-----SEDESEDGDENEEDDEDED 732

Query: 277 DSSDDSEASDDSSDDSEASDDSSDDSEAPD 306
           D  DD E  D+ S+ S +S  SS DS   D
Sbjct: 733 DDEDDDEDEDNESEGSSSSSSSSGDSSDSD 762



 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 32/107 (29%), Positives = 53/107 (49%), Gaps = 5/107 (4%)

Query: 172 NSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDD 231
           N   S     +  +S+  D+  +D  D++ ++  D+N D S+   D S+ S     S D+
Sbjct: 663 NPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-----SEDE 717

Query: 232 SDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDS 278
           S+  D++ +D E  DD  DD E  D+ S+ S +   SS DS   D +
Sbjct: 718 SEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 29/90 (32%), Positives = 44/90 (48%), Gaps = 4/90 (4%)

Query: 124 SDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 183
           S+ + DD+   D    D++ D+ E  D+N D SE   D+S+ S   +    D    DD  
Sbjct: 675 SESEEDDEEDED----DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 730

Query: 184 DDSDVPDDNSDDSSDDNSDDSSDDNSDDSD 213
           +D D  DD  +D+  + S  SS  + D SD
Sbjct: 731 EDDDEDDDEDEDNESEGSSSSSSSSGDSSD 760



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 32/89 (35%), Positives = 51/89 (57%), Gaps = 6/89 (6%)

Query: 125 DDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD 184
           ++D DD++ ++ E  D+N D SE   D+S+ S     + D+SE  D+N +D E  DD+ D
Sbjct: 682 EEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-----SEDESEDGDENEEDDEDEDDDED 736

Query: 185 DSDVPDDNSDDSSDDNSDDSSDDNSDDSD 213
           D D  +DN  + S  +S  S D +  DS+
Sbjct: 737 D-DEDEDNESEGSSSSSSSSGDSSDSDSN 764



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 3/99 (3%)

Query: 215 PDDKSDDSDVPDDSS---DDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDD 271
           P+ KS  + +   S    DD +  DD  +D E  DD + DS      S +S + D+S D 
Sbjct: 662 PNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDG 721

Query: 272 SEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSD 310
            E  +D  D+ +  DD  D+   S+ SS  S +  D SD
Sbjct: 722 DENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSD 760



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 28/89 (31%), Positives = 44/89 (49%)

Query: 150 DDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNS 209
           +   DD E  DD  +D E  DD + DS     +S +S   D++ D   ++  D+  DD+ 
Sbjct: 676 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 735

Query: 210 DDSDVPDDKSDDSDVPDDSSDDSDVPDDS 238
           DD +  D++S+ S     SS DS   D +
Sbjct: 736 DDDEDEDNESEGSSSSSSSSGDSSDSDSN 764



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 25/92 (27%), Positives = 45/92 (48%)

Query: 142 NSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNS 201
           +  +SE  D+  +D E  D+  +D E  D + D  ++ + +S+D     D +++  +D  
Sbjct: 673 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 732

Query: 202 DDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSD 233
           DD  DD  +D++     S  S   D S  DS+
Sbjct: 733 DDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 28/85 (32%), Positives = 40/85 (47%)

Query: 246 DDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAP 305
           +   DD E  DD  +D E  DD + DS      S +S + D+S D  E  +D  D+ +  
Sbjct: 676 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 735

Query: 306 DDKSDDSDVPEDKSDDSDVPDDNSD 330
           DD  D+ +  E  S  S    D+SD
Sbjct: 736 DDDEDEDNESEGSSSSSSSSGDSSD 760



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 29/85 (34%), Positives = 47/85 (55%), Gaps = 1/85 (1%)

Query: 248 SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDD-SEASDDSSDDSEAPD 306
           S  +SE  D+  +D E  D+  +D E  D S D  ++S+ SS+D SE  D++ +D E  D
Sbjct: 673 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 732

Query: 307 DKSDDSDVPEDKSDDSDVPDDNSDD 331
           D  DD +  +++S+ S     +S D
Sbjct: 733 DDEDDDEDEDNESEGSSSSSSSSGD 757



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 7/93 (7%)

Query: 124 SDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 183
           S++D+++D        DD  +D E  DD + DS     +S +S + D++ D  E  +D+ 
Sbjct: 677 SEEDDEEDE-------DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDE 729

Query: 184 DDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPD 216
           D+ D  DD+ D+ ++     SS  +S DS   D
Sbjct: 730 DEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 762



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 13/103 (12%)

Query: 272 SEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDD 331
           S++  +  D+ +  D+  D+ E  D++ D SE   D S+ S   ED+S+D    D+N +D
Sbjct: 673 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSS--EDESEDG---DENEED 727

Query: 332 LEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQD 374
            E     ED         DE+E  E+  + S   SS D+ + D
Sbjct: 728 DEDEDDDED--------DDEDEDNESEGSSSSSSSSGDSSDSD 762



 Score = 36.6 bits (83), Expect = 0.080
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 5/91 (5%)

Query: 82  DSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDD 141
           + DEE    E++  +  +  + D S +      +  E      D++ +DD     E  DD
Sbjct: 679 EDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDD-----EDEDD 733

Query: 142 NSDDSEAPDDNSDDSEAPDDNSDDSEAPDDN 172
           + DD E  D+ S+ S +   +S DS   D N
Sbjct: 734 DEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764


>gi|48255931 hepatoma-derived growth factor-related protein 2
           isoform 1 [Homo sapiens]
          Length = 671

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 84/367 (22%), Positives = 137/367 (37%), Gaps = 27/367 (7%)

Query: 146 SEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSS 205
           S  P  +S DSEAP+ N  D    D++ +D       +  +    D  +  SD +SD SS
Sbjct: 93  SAPPPVSSSDSEAPEANPADGSDADEDDEDRGVMAVTAVTATAASDRME--SDSDSDKSS 150

Query: 206 DDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPD-DSSDDSEA 264
           D++      P  K   S     +S D D    S  + E  + SS+  +  D D + + +A
Sbjct: 151 DNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKA 210

Query: 265 --------PDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPE 316
                   P       +AP  S  DS+A  D +     +   S  S +    S DSDV  
Sbjct: 211 AVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSV 270

Query: 317 DKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLG 376
            K      P +    L  P   +        +S  +   +    +S+    D+A  ++L 
Sbjct: 271 KKPPRGRKPAEK--PLPKPRGRKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELE 328

Query: 377 ENLSKPPSDP-----EANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRKRQTKT 431
               +   +      E   E  ER+    +         G    + +   EP +KR  K 
Sbjct: 329 ARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPVKKRGRKG 388

Query: 432 KNIVEPPRKRQTKTKNIVEPLRKRKAKTKNVSVT-----PGHKK---RGPSKKKPGAAKV 483
           +    PP    ++ +  +E   K+ AK    S T     PG K+   R   K++    KV
Sbjct: 389 RG-RGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKV 447

Query: 484 EKRKTRT 490
           E+ + R+
Sbjct: 448 ERTRKRS 454



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 88/384 (22%), Positives = 133/384 (34%), Gaps = 59/384 (15%)

Query: 101 NSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPD 160
           +SD E+PE           P   SD D DD++   + V    +  +    ++  DS+   
Sbjct: 100 SSDSEAPEA---------NPADGSDADEDDEDRGVMAVTAVTATAASDRMESDSDSDKSS 150

Query: 161 DNSD-DSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKS 219
           DNS    + P      S+     S  SD+   +   S ++NS+ SS+          +K+
Sbjct: 151 DNSGLKRKTPALKMSVSKRARKAS--SDLDQASVSPSEEENSESSSE---------SEKT 199

Query: 220 DDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSS 279
            D D   +       P         P       +AP  S  DS+A  D +         S
Sbjct: 200 SDQDFTPEKKAAVRAP------RRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARS 253

Query: 280 DDSEASDDSSDDSEASDDSSDDSEAPDD---------KSDDSDVPEDKSDDSDVPDDNSD 330
             S +S  SS DS+ S         P +         K      P   S DSD   D  D
Sbjct: 254 ASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSDSD--SDEVD 311

Query: 331 DLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSD--------DAGEQDLGENLSKP 382
            +      ++       A    E  E    + + +  +        D GE + G   S  
Sbjct: 312 RISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSG 371

Query: 383 PSDPEANPEVSER---------KLPTEEEPAPVVEQSGKRKSK--TKTIVEPPRKRQTKT 431
               E +  V +R            ++ EP   +E+  K+ +K    +  EP RK   K 
Sbjct: 372 DELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARKPGQKE 431

Query: 432 KNIVEPPRKRQTKTKNIVEPLRKR 455
           K  V P  K+Q K    VE  RKR
Sbjct: 432 KR-VRPEEKQQAKPVK-VERTRKR 453



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 66/329 (20%), Positives = 116/329 (35%), Gaps = 45/329 (13%)

Query: 235 PDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDS-- 292
           P  SS DSEAP+ +  D    D+  +D      ++  + A  D  +    SD SSD+S  
Sbjct: 96  PPVSSSDSEAPEANPADGSDADEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGL 155

Query: 293 ----------------EASDDSSDDSEAP-DDKSDDSDVPEDKSDDSDVPDDNSDDLEVP 335
                           +AS D    S +P ++++ +S    +K+ D D   +    +  P
Sbjct: 156 KRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAP 215

Query: 336 -------------VPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKP 382
                          A D  ++      + E V  A + S   SS  + + D+  ++ KP
Sbjct: 216 RRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDV--SVKKP 273

Query: 383 P--SDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRKRQTKTKNIVEPPRK 440
           P    P   P    R    + E  P    S     +   I E  R+ + + + +    R+
Sbjct: 274 PRGRKPAEKPLPKPRGRKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRR 333

Query: 441 RQTKTKNIVEPLRKRKAKTKNVSVTPGHKKRGP---------SKKKPGAAKVEKRKTRTP 491
            Q +    +    K + + +      G  +RG             +P   +  K + R P
Sbjct: 334 EQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPVKKRGRKGRGRGP 393

Query: 492 KCKVPGCFLQDLEKSKKYSGKNLKRNKDE 520
                     +LE+  K S K  + +  E
Sbjct: 394 PSSSDSEPEAELEREAKKSAKKPQSSSTE 422



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 91/430 (21%), Positives = 154/430 (35%), Gaps = 65/430 (15%)

Query: 128 NDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNS-------------DDSEAPDDNSD 174
           +D D  +     ++NS+ S   +  SD    P+  +                +AP  +  
Sbjct: 175 SDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDS 234

Query: 175 DSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDV 234
           DS+A  D +    V    S  SS      SS  +S DSDV   K      P  +      
Sbjct: 235 DSKADSDGAKPEPVAMARSASSS------SSSSSSSDSDVSVKKPPRGRKP--AEKPLPK 286

Query: 235 PDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEA 294
           P       E P  SS        S  DS+  D  S+     +    + EA      + E 
Sbjct: 287 PRGRKPKPERPPSSS-------SSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEEL 339

Query: 295 SDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEEL 354
                 + E  + + + +D  E +        D   + + PV        G+        
Sbjct: 340 RRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPVKKRGRKGRGR-------- 391

Query: 355 VEAAAAVSQHDSSDDAG-EQDLGENLSKPPS---DPEANPEVSERKLPTEE--EPAPV-V 407
                  S  DS  +A  E++  ++  KP S   +P   P   E+++  EE  +  PV V
Sbjct: 392 ----GPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKV 447

Query: 408 EQSGKR-----------KSKTKTIVEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRK 456
           E++ KR           K K  ++ E  +K  ++ K  ++       +  N +E L   +
Sbjct: 448 ERTRKRSEGFSMDRKVEKKKEPSVEEKLQKLHSEIKFALKVDSPDVKRCLNALEELGTLQ 507

Query: 457 AKT----KNVSVTPGHKK-RGPSKKKPGAAKVEKRKTRTPKCKVPGCFLQDLEKSKKYSG 511
             +    KN  V    KK R     K    K  +  TR  K +V G  ++ ++K  K +G
Sbjct: 508 VTSQILQKNTDVVATLKKIRRYKANKDVMEKAAEVYTRL-KSRVLGPKIEAVQKVNK-AG 565

Query: 512 KNLKRNKDEL 521
              ++ +++L
Sbjct: 566 MEKEKAEEKL 575



 Score = 31.6 bits (70), Expect = 2.6
 Identities = 23/90 (25%), Positives = 37/90 (41%), Gaps = 8/90 (8%)

Query: 301 DSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEE-----ELV 355
           + E  ++K    ++  +++      D  S DL  PV  E    +G+ A D+E     +  
Sbjct: 567 EKEKAEEKLAGEELAGEEAPQEKAEDKPSTDLSAPVNGEATSQKGESAEDKEHEEGRDSE 626

Query: 356 EAAAAVSQHDSSDDAGEQDLGENLSKPPSD 385
           E     S  D  D   E   G +L +P SD
Sbjct: 627 EGPRCGSSEDLHDSVRE---GPDLDRPGSD 653


>gi|14249158 hepatoma-derived growth factor-related protein 2
           isoform 2 [Homo sapiens]
          Length = 670

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 84/367 (22%), Positives = 137/367 (37%), Gaps = 27/367 (7%)

Query: 146 SEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSS 205
           S  P  +S DSEAP+ N  D    D++ +D       +  +    D  +  SD +SD SS
Sbjct: 93  SAPPPVSSSDSEAPEANPADGSDADEDDEDRGVMAVTAVTATAASDRME--SDSDSDKSS 150

Query: 206 DDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPD-DSSDDSEA 264
           D++      P  K   S     +S D D    S  + E  + SS+  +  D D + + +A
Sbjct: 151 DNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKA 210

Query: 265 --------PDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPE 316
                   P       +AP  S  DS+A  D +     +   S  S +    S DSDV  
Sbjct: 211 AVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSV 270

Query: 317 DKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLG 376
            K      P +    L  P   +        +S  +   +    +S+    D+A  ++L 
Sbjct: 271 KKPPRGRKPAEK--PLPKPRGRKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELE 328

Query: 377 ENLSKPPSDP-----EANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRKRQTKT 431
               +   +      E   E  ER+    +         G    + +   EP +KR  K 
Sbjct: 329 ARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPVKKRGRKG 388

Query: 432 KNIVEPPRKRQTKTKNIVEPLRKRKAKTKNVSVT-----PGHKK---RGPSKKKPGAAKV 483
           +    PP    ++ +  +E   K+ AK    S T     PG K+   R   K++    KV
Sbjct: 389 RG-RGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKV 447

Query: 484 EKRKTRT 490
           E+ + R+
Sbjct: 448 ERTRKRS 454



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 88/384 (22%), Positives = 133/384 (34%), Gaps = 59/384 (15%)

Query: 101 NSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPD 160
           +SD E+PE           P   SD D DD++   + V    +  +    ++  DS+   
Sbjct: 100 SSDSEAPEA---------NPADGSDADEDDEDRGVMAVTAVTATAASDRMESDSDSDKSS 150

Query: 161 DNSD-DSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKS 219
           DNS    + P      S+     S  SD+   +   S ++NS+ SS+          +K+
Sbjct: 151 DNSGLKRKTPALKMSVSKRARKAS--SDLDQASVSPSEEENSESSSE---------SEKT 199

Query: 220 DDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSS 279
            D D   +       P         P       +AP  S  DS+A  D +         S
Sbjct: 200 SDQDFTPEKKAAVRAP------RRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARS 253

Query: 280 DDSEASDDSSDDSEASDDSSDDSEAPDD---------KSDDSDVPEDKSDDSDVPDDNSD 330
             S +S  SS DS+ S         P +         K      P   S DSD   D  D
Sbjct: 254 ASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSDSD--SDEVD 311

Query: 331 DLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSD--------DAGEQDLGENLSKP 382
            +      ++       A    E  E    + + +  +        D GE + G   S  
Sbjct: 312 RISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSG 371

Query: 383 PSDPEANPEVSER---------KLPTEEEPAPVVEQSGKRKSK--TKTIVEPPRKRQTKT 431
               E +  V +R            ++ EP   +E+  K+ +K    +  EP RK   K 
Sbjct: 372 DELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARKPGQKE 431

Query: 432 KNIVEPPRKRQTKTKNIVEPLRKR 455
           K  V P  K+Q K    VE  RKR
Sbjct: 432 KR-VRPEEKQQAKPVK-VERTRKR 453



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 66/329 (20%), Positives = 116/329 (35%), Gaps = 45/329 (13%)

Query: 235 PDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDS-- 292
           P  SS DSEAP+ +  D    D+  +D      ++  + A  D  +    SD SSD+S  
Sbjct: 96  PPVSSSDSEAPEANPADGSDADEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGL 155

Query: 293 ----------------EASDDSSDDSEAP-DDKSDDSDVPEDKSDDSDVPDDNSDDLEVP 335
                           +AS D    S +P ++++ +S    +K+ D D   +    +  P
Sbjct: 156 KRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAP 215

Query: 336 -------------VPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKP 382
                          A D  ++      + E V  A + S   SS  + + D+  ++ KP
Sbjct: 216 RRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDV--SVKKP 273

Query: 383 P--SDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRKRQTKTKNIVEPPRK 440
           P    P   P    R    + E  P    S     +   I E  R+ + + + +    R+
Sbjct: 274 PRGRKPAEKPLPKPRGRKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRR 333

Query: 441 RQTKTKNIVEPLRKRKAKTKNVSVTPGHKKRGP---------SKKKPGAAKVEKRKTRTP 491
            Q +    +    K + + +      G  +RG             +P   +  K + R P
Sbjct: 334 EQEEELRRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPVKKRGRKGRGRGP 393

Query: 492 KCKVPGCFLQDLEKSKKYSGKNLKRNKDE 520
                     +LE+  K S K  + +  E
Sbjct: 394 PSSSDSEPEAELEREAKKSAKKPQSSSTE 422



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 91/430 (21%), Positives = 154/430 (35%), Gaps = 65/430 (15%)

Query: 128 NDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNS-------------DDSEAPDDNSD 174
           +D D  +     ++NS+ S   +  SD    P+  +                +AP  +  
Sbjct: 175 SDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDS 234

Query: 175 DSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDV 234
           DS+A  D +    V    S  SS      SS  +S DSDV   K      P  +      
Sbjct: 235 DSKADSDGAKPEPVAMARSASSS------SSSSSSSDSDVSVKKPPRGRKP--AEKPLPK 286

Query: 235 PDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEA 294
           P       E P  SS        S  DS+  D  S+     +    + EA      + E 
Sbjct: 287 PRGRKPKPERPPSSS-------SSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEEL 339

Query: 295 SDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEEL 354
                 + E  + + + +D  E +        D   + + PV        G+        
Sbjct: 340 RRLREQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPVKKRGRKGRGR-------- 391

Query: 355 VEAAAAVSQHDSSDDAG-EQDLGENLSKPPS---DPEANPEVSERKLPTEE--EPAPV-V 407
                  S  DS  +A  E++  ++  KP S   +P   P   E+++  EE  +  PV V
Sbjct: 392 ----GPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKV 447

Query: 408 EQSGKR-----------KSKTKTIVEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRK 456
           E++ KR           K K  ++ E  +K  ++ K  ++       +  N +E L   +
Sbjct: 448 ERTRKRSEGFSMDRKVEKKKEPSVEEKLQKLHSEIKFALKVDSPDVKRCLNALEELGTLQ 507

Query: 457 AKT----KNVSVTPGHKK-RGPSKKKPGAAKVEKRKTRTPKCKVPGCFLQDLEKSKKYSG 511
             +    KN  V    KK R     K    K  +  TR  K +V G  ++ ++K  K +G
Sbjct: 508 VTSQILQKNTDVVATLKKIRRYKANKDVMEKAAEVYTRL-KSRVLGPKIEAVQKVNK-AG 565

Query: 512 KNLKRNKDEL 521
              ++ +++L
Sbjct: 566 MEKEKAEEKL 575



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 1/86 (1%)

Query: 301 DSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEE-ELVEAAA 359
           + E  ++K    ++  +++      D  S DL  PV  E    +G+ A D+E E    + 
Sbjct: 567 EKEKAEEKLAGEELAGEEAPQEKAEDKPSTDLSAPVNGEATSQKGESAEDKEHEEGRDSE 626

Query: 360 AVSQHDSSDDAGEQDLGENLSKPPSD 385
              +  SS+D  +   G +L +P SD
Sbjct: 627 EGPRCGSSEDLHDVREGPDLDRPGSD 652



 Score = 29.6 bits (65), Expect = 9.8
 Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 6/90 (6%)

Query: 243 EAPDDSSDDSEAPDDSSD-DSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDD 301
           EAP + ++D  + D S+  + EA   +S   E+ +D   +     +      +S+D  D 
Sbjct: 584 EAPQEKAEDKPSTDLSAPVNGEA---TSQKGESAEDKEHEEGRDSEEGPRCGSSEDLHDV 640

Query: 302 SEAPDDKSDDSDVPEDK--SDDSDVPDDNS 329
            E PD     SD  E +    DS+  D+ S
Sbjct: 641 REGPDLDRPGSDRQERERARGDSEALDEES 670


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 83/463 (17%), Positives = 176/463 (38%), Gaps = 31/463 (6%)

Query: 70  KRQASSVVVIDSDSDE----ECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISD 125
           ++     V+++  ++E    E  T EE+K    E   ++E  E    +   +E     ++
Sbjct: 448 EKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAE 507

Query: 126 DDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDD 185
           +    +      V ++    +EA     +++++P +     +A     +++++P      
Sbjct: 508 EAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP------ 561

Query: 186 SDVPDDNSDDSSDDNSD-DSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEA 244
              P+  S +  +  S  +        S   ++    ++        S V +++   +EA
Sbjct: 562 ---PEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEA 618

Query: 245 PDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDD--SSDDSEASDDSSDDSEASDDSSDDS 302
                +++++P +     +A   + +++++P+   S +  EA       S    ++    
Sbjct: 619 KSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPE 678

Query: 303 EAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVS 362
           +A      ++  PE           + +  + PV  E    E   +  +EE     A   
Sbjct: 679 KAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEE-----AKTP 733

Query: 363 QHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEP-APVVEQSGKRKSKTKTIV 421
           +   S    E    E    P      + +  E K P +EE  +P  +   K KS  K  V
Sbjct: 734 EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEV 793

Query: 422 EPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRKAKTKNVSVTPGHKKRGPSKKKPGAA 481
           + P K ++  K   + P K   K + +  P+ K + K + V V    KK    +K P   
Sbjct: 794 KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV-KEEEKPQEVKVKEPPKK-AEEEKAPATP 851

Query: 482 KVEK----RKTRTPKCKVPGCFLQDLEKSKKYSGKNLKRNKDE 520
           K E+    +K   PK + P      +E+ K+ + +  K +K E
Sbjct: 852 KTEEKKDSKKEEAPKKEAP---KPKVEEKKEPAVEKPKESKVE 891



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 82/512 (16%), Positives = 208/512 (40%), Gaps = 77/512 (15%)

Query: 68   APKRQASSVVVIDSDSDEECHTHEEKKAKL-LEINSDDESPECCHVKPAIQEPPIVISDD 126
            +P+++A S V  ++ S  E  + E+++AK   E+ S +++      K   + PP   S +
Sbjct: 511  SPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKS--PAKEEAKSPPEAKSPE 568

Query: 127  DNDDDNGNDLEVPDDNS----DDSEAP--------------DDNSDDSEAPDDNSDDSEA 168
              +  +  +++ P+       +++++P              ++    +EA     +++++
Sbjct: 569  KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKS 628

Query: 169  PDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDS 228
            P +     +A     +++  P+       ++        +   ++    +   S V  ++
Sbjct: 629  PAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEA 688

Query: 229  SDDSDVPDDSSDDSEAPDDSS----DDSEAPDDSS----DDSEAPDDSS----DDSEAPD 276
                       +++++P+ +     +++++P+ +     ++++ P+ +     +++++P+
Sbjct: 689  KSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPE 748

Query: 277  DSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDD-----------------SDVPED-K 318
             +    +A        EA   + +++ +P DK  +                 S + ED K
Sbjct: 749  KAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK 808

Query: 319  SDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAA-AVSQHDSSDDAGEQDLGE 377
            + + ++P    ++++ PV  E+   E ++    ++  E  A A  + +   D+ +++   
Sbjct: 809  APEKEIP--KKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEA-- 864

Query: 378  NLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRKR---QTKTKNI 434
                 P      P+V E+K P  E+P     ++ K +++ K  V  P K    + + K  
Sbjct: 865  -----PKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKED 919

Query: 435  VEPPRKRQ--------TKTKNIVEPLRKRKAKTKNVSVTPGHKKRGPSKKKPGAAKVEKR 486
             +P  K +         K K   +P  K++A  +         K+   K K  A   E  
Sbjct: 920  AKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDD 979

Query: 487  KTRTPKCKVPGCFLQDLEKSKKYSGKNLKRNK 518
            KT + +   P       EK++K S  + K +K
Sbjct: 980  KTLSKEPSKP-----KAEKAEKSSSTDQKDSK 1006



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 57/372 (15%), Positives = 146/372 (39%), Gaps = 24/372 (6%)

Query: 136 LEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDD 195
           ++V + +  ++   ++ +++++  ++ +++ E      +  E  ++  ++ +      + 
Sbjct: 444 IKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKE--EEGGEEEEAEGGEEET 501

Query: 196 SSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAP 255
            S    + +S +    S V ++    ++      +++  P +     +A   + +++++P
Sbjct: 502 KSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 561

Query: 256 --------DDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDD 307
                   +++   +E        S A +++   +EA       S   +++   +EA   
Sbjct: 562 PEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSP 621

Query: 308 KSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEEL-VEAAAAVSQHDS 366
             +++  P +            ++ + P  A+    E   + ++ +  V+A A   +   
Sbjct: 622 VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK 681

Query: 367 SDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRK 426
           S    E    E    P  +   +PE ++  +  E +     +   K ++KT    + P K
Sbjct: 682 SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVK 741

Query: 427 RQTKTKNIVEPPRKRQTKTKNIVEPLRKRKAKTKNVSVTPGHKKRGPSKKKPGAAKVE-K 485
            + K+    + P K   KT ++  P  K  AK          + R P+ K P  AK   K
Sbjct: 742 EEAKSPEKAKSPEK--AKTLDVKSPEAKTPAK---------EEARSPADKFPEKAKSPVK 790

Query: 486 RKTRTP-KCKVP 496
            + ++P K K P
Sbjct: 791 EEVKSPEKAKSP 802



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 81/444 (18%), Positives = 160/444 (36%), Gaps = 29/444 (6%)

Query: 6   KELPRLQEPEEDEDCYILNVQSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVA 65
           K  P  + PE++E      V+S     S +    ++P    S          +    + A
Sbjct: 559 KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEA 618

Query: 66  RRAPKRQASSVVVIDSDSDEECHTHEE----KKAKLLEINSDDESPECCH--VKPAIQEP 119
           +   K +A S   + S    +  T EE    +KAK  E   + +SPE     VK   + P
Sbjct: 619 KSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE-KEEAKSPEKAKSPVKAEAKSP 677

Query: 120 PIVISDDDNDDDNGNDLEVP--DDNSDDSEAPDDNSDDSEAPDDNSDD--SEAPDDNSDD 175
               S    +  +    + P  ++     +A     +++++P+        EA       
Sbjct: 678 EKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAK 737

Query: 176 SEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDD---SDVPDDSSDDS 232
           S   ++              + D  S ++     +++  P DK  +   S V ++     
Sbjct: 738 SPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPE 797

Query: 233 DVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDS 292
                  +D++AP+      E       + E P +            + + A+  + +  
Sbjct: 798 KAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKK 857

Query: 293 EASDDSSDDSEAPDDKSDDSDVPE-DKSDDSDVP---DDNSDDLEVPVPAEDLCNEGQIA 348
           ++  + +   EAP  K ++   P  +K  +S V    ++  D  +VP P ++   + ++ 
Sbjct: 858 DSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVK 917

Query: 349 SDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVE 408
            D +   +   A  + D +            +K PS P    E +  K  T+EE A   E
Sbjct: 918 EDAKPKEKTEVAKKEPDDAK-----------AKEPSKPAEKKEAAPEKKDTKEEKAKKPE 966

Query: 409 QSGKRKSKTKTIVEPPRKRQTKTK 432
           +  K ++K K   +   K  +K K
Sbjct: 967 EKPKTEAKAKEDDKTLSKEPSKPK 990



 Score = 37.7 bits (86), Expect = 0.036
 Identities = 58/329 (17%), Positives = 128/329 (38%), Gaps = 39/329 (11%)

Query: 6    KELPRLQEPEEDEDCYILNVQSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVA 65
            K   + + P ++E       +S   + + S    ++P++  +  L+V+S    T     A
Sbjct: 717  KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKT--LDVKSPEAKTPAKEEA 774

Query: 66   R----RAPKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPI 121
            R    + P++  S V        EE  + E+ K+ L E   D ++PE    K    + P+
Sbjct: 775  RSPADKFPEKAKSPV-------KEEVKSPEKAKSPLKE---DAKAPEKEIPKKEEVKSPV 824

Query: 122  VISDDDNDDDNGNDLEV--PDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAP 179
                   +++   +++V  P   +++ +AP     + +    +S   EAP   +   +  
Sbjct: 825  ------KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKK---DSKKEEAPKKEAPKPKVE 875

Query: 180  DDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPD--DKSDDSDVPDDSSDDSDVPDD 237
            +      + P ++  ++  + ++D     + + + P   +  +D+   + +      PDD
Sbjct: 876  EKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDD 935

Query: 238  SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDD 297
            +   ++ P   ++  EA  +  D  E  + +    E P   +   E      DD   S +
Sbjct: 936  AK--AKEPSKPAEKKEAAPEKKDTKE--EKAKKPEEKPKTEAKAKE------DDKTLSKE 985

Query: 298  SSDDSEAPDDKSDDSDVPEDKSDDSDVPD 326
             S       +KS  +D  + K  +    D
Sbjct: 986  PSKPKAEKAEKSSSTDQKDSKPPEKATED 1014


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 86/368 (23%), Positives = 139/368 (37%), Gaps = 45/368 (12%)

Query: 53   QSRSGDTSGSSVARRAPKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHV 112
            ++R+ + SG+   RR P  +A  +V +D +      + + K+A LL      E P     
Sbjct: 2439 KARAAEESGAKGPRR-PGEEAELLVKLDHEGVTSPKSKKAKEALLLR-----EDPGA--- 2489

Query: 113  KPAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDN 172
                QEP  ++S        G+     +  +   +A D +      P    +DS  P  +
Sbjct: 2490 -GGWQEPKSLLSLGSYPPAAGSS----EPKAPWPKATDGDLAQEPGPGLTFEDSGNPK-S 2543

Query: 173  SDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDS 232
             D ++A  D +++S+    +S  SS  +S  SS  +  + +   DK+ D        + S
Sbjct: 2544 PDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCS 2603

Query: 233  DVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDS 292
                 +S  + +P  SS  S +   SS  S +   SS  S +   SS  S +S  SS  S
Sbjct: 2604 A----ASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2659

Query: 293  EASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEE 352
             +S  SS  S +  D        ED S        +SDD   P P        Q A   +
Sbjct: 2660 SSSSSSSSSSSSTTD--------EDSSC-------SSDDEAAPAPTAG--PSAQAALPTK 2702

Query: 353  ELVEAAAAVSQHDSSDDAGEQDLGENLSKPPS------DPEANPEVSERKLPTEEEPAPV 406
               +A  A     S+   G++        PP        P+A      R    E    P 
Sbjct: 2703 ATKQAGKA---RPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPT 2759

Query: 407  VEQSGKRK 414
             ++  KR+
Sbjct: 2760 TKELAKRQ 2767



 Score = 30.0 bits (66), Expect = 7.5
 Identities = 32/138 (23%), Positives = 49/138 (35%), Gaps = 5/138 (3%)

Query: 362  SQHDSSDDAGEQDLGENLSKPPSDP--EANPEVSERKLPTEEEPAPVVEQSGKRKSKTKT 419
            S  D +  A E+       + P +P  EA PE S+  L T      +        +    
Sbjct: 1956 SSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPV 2015

Query: 420  IVEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRKAKT--KNVSVTPGHKKRGPSK-K 476
               P  K     K     PRK   + K+  +P +K+K K       + P      PS+ +
Sbjct: 2016 STAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEAR 2075

Query: 477  KPGAAKVEKRKTRTPKCK 494
             P A+ +   K    K K
Sbjct: 2076 APHASSLTAAKRSKAKAK 2093


>gi|42518068 trans-golgi network protein 2 [Homo sapiens]
          Length = 437

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 65/300 (21%), Positives = 111/300 (37%), Gaps = 29/300 (9%)

Query: 127 DNDDDNGNDLEVPDDNSDDSEAPDDNSDDS------EAPDDNSDDSEAPDDNSDDSEAPD 180
           D+   +  + + P+D  + S A      DS      EA       S++  +     ++  
Sbjct: 65  DSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTS 124

Query: 181 DNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSD 240
            +  +   P D++  S  +        N   ++    K   S    ++    DVP+ S  
Sbjct: 125 KSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGA 184

Query: 241 DSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSD 300
           D + P D S  S A D +  D   P+ S  + + P D S+ S A +    D  +    S 
Sbjct: 185 DGQTPKDGSSKSGAEDQTPKD--VPNKSGAEKQTPKDGSNKSGAEEQGPIDGPS---KSG 239

Query: 301 DSEAPDDKSDDSDVPEDKS--DDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAA 358
             E     S +  VPE  S  D S    + SD+ E+P             +D  +L +  
Sbjct: 240 AEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELP------------KADTNQLAD-K 286

Query: 359 AAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTK 418
             +S H    ++GE+    +L  PP +   + E +E   P E E      + G    + K
Sbjct: 287 GKLSPHAFKTESGEE---TDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEK 343



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 66/333 (19%), Positives = 124/333 (37%), Gaps = 39/333 (11%)

Query: 3   GCKKELPRLQEPEEDEDCYILNVQSSSDDTSGSSVARRAPKRQASCI-LNVQSRSGDTSG 61
           G  K  P  Q P++         Q+  D  + S    +  K  ++      +++ G TS 
Sbjct: 52  GSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSK 111

Query: 62  SSVARRAPKRQASSVVVIDSDSDEECHTHEEKKAKL-LEINSDDESPECCHVKPAIQEPP 120
           S    +  K   S        S  E  T ++   K   E  + ++SP     +   Q+  
Sbjct: 112 SGSEAQTTKDSTSK-------SHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKD- 163

Query: 121 IVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPD 180
              S   +  +     +VP+ +  D + P D S  S A D    D   P+ +  + + P 
Sbjct: 164 ---SPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKD--VPNKSGAEKQTPK 218

Query: 181 DNSDDSDVPDDNS-DDSSDDNSDDSSDDNSDDSDVPDDKS--DDSDVPDDSSDDSDVPDD 237
           D S+ S   +    D  S   +++ +  +S +  VP+  S  D S    + SD+ ++P  
Sbjct: 219 DGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELP-- 276

Query: 238 SSDDSEAPD--------------DSSDDSEAPDDSSDDSEA-----PDDSSDDSEAPDDS 278
            +D ++  D              + +D    P +    SE      P ++ DD   P++ 
Sbjct: 277 KADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEG 336

Query: 279 SDDSEASDDSSDDSEASDDSSDDSEAPDDKSDD 311
           S   E  +  S  + + +     S++   + DD
Sbjct: 337 SPPKEEKEKMSGSASSENREGTLSDSTGSEKDD 369



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 65/318 (20%), Positives = 123/318 (38%), Gaps = 45/318 (14%)

Query: 201 SDDSSDDNSDDSDVPDDKSDDSDVPDD----SSDDSDVPDDSSDDSEA--------PDDS 248
           S  S  +     D P   S ++  P+D    S  ++    DSS+ S A           S
Sbjct: 53  STKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKS 112

Query: 249 SDDSEAPDDSSDDS----EAPDDSSD----DSEAPDDSSDDS--EASDDSSDDSEASDDS 298
             +++   DS+  S    + P DS+     +++ P+DS + S  EA       S++  ++
Sbjct: 113 GSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEA 172

Query: 299 SDDSEAPDDKSDDSDVPEDKSDDS--------DVPDDNSDDLEVPVPAEDLCN-EGQIAS 349
               + P+    D   P+D S  S        DVP+ +  + + P    +    E Q   
Sbjct: 173 QTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPI 232

Query: 350 DEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQ 409
           D      A    S+   +    EQ   ++ SKP S+P  N E+ +       +   +   
Sbjct: 233 DGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPH 292

Query: 410 SGKRKSKTKTIVEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRKAKTKNVSVTPGHK 469
           + K +S  +T             +++ PP++ + K+    E +  ++A+  +     G  
Sbjct: 293 AFKTESGEET-------------DLISPPQE-EVKSSEPTEDVEPKEAEDDDTGPEEGSP 338

Query: 470 KRGPSKKKPGAAKVEKRK 487
            +   +K  G+A  E R+
Sbjct: 339 PKEEKEKMSGSASSENRE 356



 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 66/309 (21%), Positives = 117/309 (37%), Gaps = 47/309 (15%)

Query: 26  QSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQASSVVVIDSDSDE 85
           Q+  D  S SS   + P+              DT   S A    ++ +S+       S  
Sbjct: 61  QTPKDSPSKSSAEAQTPE--------------DTPNKSGAEAKTQKDSSN------KSGA 100

Query: 86  ECHTHEEKKAKL-LEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDD--N 142
           E  T +   +K   E  +  +S    H  P +Q P       D+   +G + + P+D  N
Sbjct: 101 EAKTQKGSTSKSGSEAQTTKDSTSKSH--PELQTPK------DSTGKSGAEAQTPEDSPN 152

Query: 143 SDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDD------NSDDS 196
              +EA       S++  +     + P+ +  D + P D S  S   D       N   +
Sbjct: 153 RSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGA 212

Query: 197 SDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSD---VPDDSS--DDSEAPDDSSDD 251
                 D S+ +  +   P D    S   + +S DS    VP+  S  D S+   + SD+
Sbjct: 213 EKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDN 272

Query: 252 SEAPDDSSDDSEAPDDSSDDSEA-PDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSD 310
            E P   +D ++  D       A   +S ++++      ++ ++S+ + D    P +  D
Sbjct: 273 KELP--KADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTED--VEPKEAED 328

Query: 311 DSDVPEDKS 319
           D   PE+ S
Sbjct: 329 DDTGPEEGS 337



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 57/256 (22%), Positives = 97/256 (37%), Gaps = 25/256 (9%)

Query: 127 DNDDDNGNDLEVPDDNSDDSEA----PDD--NSDDSEAPDDNSDDSEAPDDNSDDSEAPD 180
           D+   +  +L+ P D++  S A    P+D  N   +EA       S++  +     + P+
Sbjct: 121 DSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPN 180

Query: 181 DNSDDSDVPDDNSDDSS--DDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDS 238
            +  D   P D S  S   D    D  + +  +   P D S+ S   +        P D 
Sbjct: 181 KSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQG------PIDG 234

Query: 239 SDDSEAPDDSSDDSE---APDDSS--DDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSE 293
              S A + +S DS     P+  S  D S+   + SD+ E P   +D ++ +D       
Sbjct: 235 PSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELP--KADTNQLADKGKLSPH 292

Query: 294 A----SDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIAS 349
           A    S + +D    P ++   S+  ED        DD   +   P   E     G  +S
Sbjct: 293 AFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASS 352

Query: 350 DEEELVEAAAAVSQHD 365
           +  E   + +  S+ D
Sbjct: 353 ENREGTLSDSTGSEKD 368


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 56/253 (22%), Positives = 109/253 (43%), Gaps = 16/253 (6%)

Query: 155  DSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDV 214
            DS   +D  +      +++++ E  ++  ++ D  DD+SDD  +  +DD     S+ S+ 
Sbjct: 1030 DSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEK 1089

Query: 215  PDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEA 274
             +  SD+ +     +  ++    SS+ SE+ +  S    +P  S D+ E      ++ E 
Sbjct: 1090 DEGDSDEEETVSIVTSKAEA-TSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEE 1148

Query: 275  PDDS-SDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNS---D 330
             ++  +++S AS    D  +  ++++    AP   S   +   D   ++  P++     D
Sbjct: 1149 EEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLD 1208

Query: 331  DLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANP 390
            +  +PV  E+        +D  E  E    +SQ  +   + E    E  ++PP  PE  P
Sbjct: 1209 EPPLPVGVEE-------PADSREPPE-EPGLSQEGAMLLSPEPPAKEVEARPPLSPERAP 1260

Query: 391  EVSERKLPTEEEP 403
               E  L  E EP
Sbjct: 1261 ---EHDLEVEPEP 1270



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 90/418 (21%), Positives = 153/418 (36%), Gaps = 75/418 (17%)

Query: 70   KRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDND 129
            KR   S  V + D + E     +      E+   D        +PA    P+ + D   +
Sbjct: 979  KRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPA---RPLEL-DSGGE 1034

Query: 130  DDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDD---SEAPDDNSDDSEAPDDNSDDS 186
            +D    L    +++++ E  ++  ++ +  DD+SDD   SE  D+++  SEA + +  DS
Sbjct: 1035 EDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDS 1094

Query: 187  DVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPD 246
                D  +  S   S   +  +S+ S+  + +S     P  S D+ +V     ++ E   
Sbjct: 1095 ----DEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEE--- 1147

Query: 247  DSSDDSEAPDDSSDDSEAPDDSSDDSE----APDDSSDDSEASDDSSDDSEASDDSSDDS 302
               ++ E   + S  S  P+D   D E    AP   + DS   ++         D   ++
Sbjct: 1148 ---EEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEV-------DIETEA 1197

Query: 303  EAPDDKSDDSDVP------EDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEE---E 353
             AP+++    D P      E+ +D  + P++             L  EG +    E   +
Sbjct: 1198 VAPEERPSMLDEPPLPVGVEEPADSREPPEE-----------PGLSQEGAMLLSPEPPAK 1246

Query: 354  LVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKR 413
             VEA   +    S + A E D    L   P  P   P   +  LP    P P        
Sbjct: 1247 EVEARPPL----SPERAPEHD----LEVEPEPPMMLPLPLQPPLPPPRPPRPP------- 1291

Query: 414  KSKTKTIVEPPRKRQTKTKNIVEPP----RKRQTKTKNIVEPLRKRKAKTKNVSVTPG 467
                     PP    T   +   PP          T  +   L K ++ T+ V  TPG
Sbjct: 1292 -------SPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQS-TETVPATPG 1341


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.304    0.126    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,508,697
Number of Sequences: 37866
Number of extensions: 1760391
Number of successful extensions: 44817
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 593
Number of HSP's successfully gapped in prelim test: 853
Number of HSP's that attempted gapping in prelim test: 11024
Number of HSP's gapped (non-prelim): 13649
length of query: 691
length of database: 18,247,518
effective HSP length: 109
effective length of query: 582
effective length of database: 14,120,124
effective search space: 8217912168
effective search space used: 8217912168
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press