Search of human proteins with 164419736

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2
precursor [Homo sapiens]
         (884 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2 p...  1781   0.0  
gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1 p...  1689   0.0  
gi|163659858 glutamate receptor, ionotrophic, AMPA 3 isoform 2 p...  1389   0.0  
gi|163659856 glutamate receptor, ionotrophic, AMPA 3 isoform 1 p...  1370   0.0  
gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2 pr...  1370   0.0  
gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1 pre...  1351   0.0  
gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3 [H...  1313   0.0  
gi|167001419 glutamate receptor, ionotropic, AMPA 1 isoform 1 [H...  1222   0.0  
gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2 [H...  1204   0.0  
gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3 p...   857   0.0  
gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3 p...   857   0.0  
gi|28416444 glutamate receptor, ionotropic, kainate 1 isoform 2 ...   588   e-168
gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1 ...   586   e-167
gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2 ...   586   e-167
gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor ...   585   e-167
gi|4504117 glutamate receptor, ionotropic, kainate 1 isoform 1 p...   579   e-165
gi|29029597 glutamate receptor KA2 precursor [Homo sapiens]           499   e-141
gi|29029595 glutamate receptor KA1 precursor [Homo sapiens]           496   e-140
gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens]   337   4e-92
gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [H...   332   7e-91
gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens]    221   2e-57
gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens]    218   2e-56
gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens]    218   2e-56
gi|55770854 N-methyl-D-aspartate receptor subunit 2C precursor [...   194   2e-49
gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor ...   191   3e-48
gi|197313638 N-methyl-D-aspartate receptor subunit 2A isoform 2 ...   172   2e-42
gi|197313636 N-methyl-D-aspartate receptor subunit 2A isoform 1 ...   172   2e-42
gi|4504125 N-methyl-D-aspartate receptor subunit 2A isoform 1 pr...   172   2e-42
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ...   171   3e-42
gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate...   154   5e-37

>gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2
           precursor [Homo sapiens]
          Length = 884

 Score = 1781 bits (4614), Expect = 0.0
 Identities = 884/884 (100%), Positives = 884/884 (100%)

Query: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
           MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
Sbjct: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60

Query: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
           PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
Sbjct: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120

Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
           SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180

Query: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
           VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
Sbjct: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240

Query: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
           NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL
Sbjct: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300

Query: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
           TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
Sbjct: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360

Query: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
           VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT
Sbjct: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420

Query: 421 TIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTK 480
           TIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTK
Sbjct: 421 TIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTK 480

Query: 481 IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 540
           IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL
Sbjct: 481 IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 540

Query: 541 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLW 600
           DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLW
Sbjct: 541 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLW 600

Query: 601 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 660
           FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED
Sbjct: 601 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 660

Query: 661 LAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKG 720
           LAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKG
Sbjct: 661 LAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKG 720

Query: 721 KFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGL 780
           KFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGL
Sbjct: 721 KFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGL 780

Query: 781 LDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKS 840
           LDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKS
Sbjct: 781 LDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKS 840

Query: 841 RAEAKRMKVAKSAQTFNPTSSQNTQNLATYREGYNVYGTESIKI 884
           RAEAKRMKVAKSAQTFNPTSSQNTQNLATYREGYNVYGTESIKI
Sbjct: 841 RAEAKRMKVAKSAQTFNPTSSQNTQNLATYREGYNVYGTESIKI 884


>gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1
           precursor [Homo sapiens]
          Length = 902

 Score = 1689 bits (4375), Expect = 0.0
 Identities = 839/852 (98%), Positives = 842/852 (98%)

Query: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
           MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
Sbjct: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60

Query: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
           PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
Sbjct: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120

Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
           SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180

Query: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
           VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
Sbjct: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240

Query: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
           NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL
Sbjct: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300

Query: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
           TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
Sbjct: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360

Query: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
           VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT
Sbjct: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420

Query: 421 TIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTK 480
           TIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTK
Sbjct: 421 TIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTK 480

Query: 481 IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 540
           IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL
Sbjct: 481 IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 540

Query: 541 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLW 600
           DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLW
Sbjct: 541 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLW 600

Query: 601 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 660
           FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED
Sbjct: 601 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 660

Query: 661 LAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKG 720
           LAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKG
Sbjct: 661 LAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKG 720

Query: 721 KFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGL 780
           KFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLG  VNLAVLKL+E G+
Sbjct: 721 KFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSEAGV 780

Query: 781 LDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKS 840
           LDKLKNKWWYDKGECG     SKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKS
Sbjct: 781 LDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKS 840

Query: 841 RAEAKRMKVAKS 852
           RAEAKRMK+  S
Sbjct: 841 RAEAKRMKLTFS 852


>gi|163659858 glutamate receptor, ionotrophic, AMPA 3 isoform 2
           precursor [Homo sapiens]
          Length = 894

 Score = 1389 bits (3596), Expect = 0.0
 Identities = 671/887 (75%), Positives = 780/887 (87%), Gaps = 9/887 (1%)

Query: 4   ISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFN 63
           + R +  L  G  G + G FP+++ IGGLF+RNT QE++AFR A+ L+NT+ N +E PF+
Sbjct: 11  VLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFH 70

Query: 64  LVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFP 123
           L  HVD+++++NSF+VTNAFCSQ+SRGV+AIFG YD+ S++TLTSFC ALH S +TPSFP
Sbjct: 71  LNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFP 130

Query: 124 TEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSA 183
           T+ + QFV+Q+RP+L+GA+LSLL HY+W  FV+LYDT+RG+SILQAIME A QN W V+A
Sbjct: 131 TDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTA 190

Query: 184 ICVENFNDVS-YRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
             V N  DV  +R+++EE+DRRQEK+++IDCE+ER+  ILEQ+V +GKH +GYHY++ANL
Sbjct: 191 RSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANL 250

Query: 243 GFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-KYTSALT 301
           GF DI LER +HGGAN+TGFQ+V+   PMV + + RW +LD+RE+P ++  P KYTSALT
Sbjct: 251 GFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALT 310

Query: 302 YDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNV 361
           +D +LV+AE FR LRRQ++D+SRRG+AGDCLANPA PW QGID+ER LK V++QG+TGN+
Sbjct: 311 HDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNI 370

Query: 362 QFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTT 421
           QFD YGRR NYT+DV+E+K +G RK GYWN+ ++ V   D   + ND+A+ ENRT+VVTT
Sbjct: 371 QFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSD-QQISNDSASSENRTIVVTT 429

Query: 422 IMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKI 481
           I+ESPYVMYKKNHE  EGN++YEGYCVDLA EIAKH+ IKYK++IV DGKYGARD +TKI
Sbjct: 430 ILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKI 489

Query: 482 WNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 541
           WNGMVGELVYG+A+IA+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD
Sbjct: 490 WNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 549

Query: 542 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH----TEEPEDGKEGPSDQPPNEFGIFN 597
           PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH     EEP D +  P   PPNEFGIFN
Sbjct: 550 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPD--PPNEFGIFN 607

Query: 598 SLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 657
           SLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES
Sbjct: 608 SLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 667

Query: 658 AEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRK 717
           AEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMW+YM+SAEPSVFT+TTA+GVARVRK
Sbjct: 668 AEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRK 727

Query: 718 SKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNE 777
           SKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGS+LGNAVNLAVLKLNE
Sbjct: 728 SKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGNAVNLAVLKLNE 787

Query: 778 QGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFC 837
           QGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAM+VALIEFC
Sbjct: 788 QGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFC 847

Query: 838 YKSRAEAKRMKVAKSAQTFNPTSSQNTQNLATYREGYNVYGTESIKI 884
           YKSRAE+KRMK+ K+ Q F P  + NTQN ATYREGYNVYGTES+KI
Sbjct: 848 YKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI 894


>gi|163659856 glutamate receptor, ionotrophic, AMPA 3 isoform 1
           precursor [Homo sapiens]
          Length = 894

 Score = 1370 bits (3547), Expect = 0.0
 Identities = 662/887 (74%), Positives = 774/887 (87%), Gaps = 9/887 (1%)

Query: 4   ISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFN 63
           + R +  L  G  G + G FP+++ IGGLF+RNT QE++AFR A+ L+NT+ N +E PF+
Sbjct: 11  VLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFH 70

Query: 64  LVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFP 123
           L  HVD+++++NSF+VTNAFCSQ+SRGV+AIFG YD+ S++TLTSFC ALH S +TPSFP
Sbjct: 71  LNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFP 130

Query: 124 TEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSA 183
           T+ + QFV+Q+RP+L+GA+LSLL HY+W  FV+LYDT+RG+SILQAIME A QN W V+A
Sbjct: 131 TDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTA 190

Query: 184 ICVENFNDVS-YRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
             V N  DV  +R+++EE+DRRQEK+++IDCE+ER+  ILEQ+V +GKH +GYHY++ANL
Sbjct: 191 RSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANL 250

Query: 243 GFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-KYTSALT 301
           GF DI LER +HGGAN+TGFQ+V+   PMV + + RW +LD+RE+P ++  P KYTSALT
Sbjct: 251 GFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALT 310

Query: 302 YDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNV 361
           +D +LV+AE FR LRRQ++D+SRRG+AGDCLANPA PW QGID+ER LK V++QG+TGN+
Sbjct: 311 HDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNI 370

Query: 362 QFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTT 421
           QFD YGRR NYT+DV+E+K +G RK GYWN+ ++ V   D   + ND+A+ ENRT+VVTT
Sbjct: 371 QFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSD-QQISNDSASSENRTIVVTT 429

Query: 422 IMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKI 481
           I+ESPYVMYKKNHE  EGN++YEGYCVDLA EIAKH+ IKYK++IV DGKYGARD +TKI
Sbjct: 430 ILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKI 489

Query: 482 WNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 541
           WNGMVGELVYG+A+IA+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD
Sbjct: 490 WNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 549

Query: 542 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH----TEEPEDGKEGPSDQPPNEFGIFN 597
           PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH     EEP D +  P   PPNEFGIFN
Sbjct: 550 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPD--PPNEFGIFN 607

Query: 598 SLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 657
           SLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES
Sbjct: 608 SLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 667

Query: 658 AEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRK 717
           AEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMW+YM+SAEPSVFT+TTA+GVARVRK
Sbjct: 668 AEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRK 727

Query: 718 SKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNE 777
           SKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGS+LG  VNLAVLKL+E
Sbjct: 728 SKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSE 787

Query: 778 QGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFC 837
           QG+LDKLKNKWWYDKGECG+    SKDKTSALSLSNVAGVFYILVGGLGLAM+VALIEFC
Sbjct: 788 QGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFC 847

Query: 838 YKSRAEAKRMKVAKSAQTFNPTSSQNTQNLATYREGYNVYGTESIKI 884
           YKSRAE+KRMK+ K+ Q F P  + NTQN ATYREGYNVYGTES+KI
Sbjct: 848 YKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI 894


>gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2
           precursor [Homo sapiens]
          Length = 883

 Score = 1370 bits (3546), Expect = 0.0
 Identities = 662/889 (74%), Positives = 773/889 (86%), Gaps = 11/889 (1%)

Query: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
           M+ I    VLL    WGL  G   +S+QIGGLF R  DQEY+AFR+ +   +TS      
Sbjct: 1   MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- 55

Query: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
            F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC  LH+S ITP
Sbjct: 56  -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP 114

Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
           SFPT+G   FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A +  W 
Sbjct: 115 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174

Query: 181 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 236
           V+AI V N N    D  YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVKGYH
Sbjct: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234

Query: 237 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 295
           YIIANLGF D  L +   GGANV+GFQ+VD++  +V K ++RW  L+++EYPG+ T   K
Sbjct: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK 294

Query: 296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 355
           YTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV+++
Sbjct: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354

Query: 356 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR 415
           GL+GN++FD  G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+       GNDT+ +EN+
Sbjct: 355 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK 414

Query: 416 TVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGAR 475
           TVVVTTI+ESPYVM KKNHEM EGN++YEGYCVDLA+EIAKH G KYK+ IV DGKYGAR
Sbjct: 415 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGAR 474

Query: 476 DADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 535
           DADTKIWNGMVGELVYGKA+IAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG
Sbjct: 475 DADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 534

Query: 536 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGI 595
           VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEE EDG+E  S +  NEFGI
Sbjct: 535 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 594

Query: 596 FNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI 655
           FNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI
Sbjct: 595 FNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI 654

Query: 656 ESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARV 715
           ESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMWTYMRSAEPSVF RTTAEGVARV
Sbjct: 655 ESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARV 714

Query: 716 RKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKL 775
           RKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSSL NAVNLAVLKL
Sbjct: 715 RKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKL 774

Query: 776 NEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIE 835
           NEQGLLDKLKNKWWYDKGECGSGGGDSK+KTSALSLSNVAGVFYILVGGLGLAMLVALIE
Sbjct: 775 NEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIE 834

Query: 836 FCYKSRAEAKRMKVAKSAQTFNPTSSQNTQNLATYREGYNVYGTESIKI 884
           FCYKSRAEAKRMKVAK+AQ  NP+SSQN+QN ATY+EGYNVYG ES+KI
Sbjct: 835 FCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883


>gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1
           precursor [Homo sapiens]
          Length = 883

 Score = 1351 bits (3496), Expect = 0.0
 Identities = 653/889 (73%), Positives = 767/889 (86%), Gaps = 11/889 (1%)

Query: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
           M+ I    VLL    WGL  G   +S+QIGGLF R  DQEY+AFR+ +   +TS      
Sbjct: 1   MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- 55

Query: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
            F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC  LH+S ITP
Sbjct: 56  -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP 114

Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
           SFPT+G   FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A +  W 
Sbjct: 115 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174

Query: 181 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 236
           V+AI V N N    D  YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVKGYH
Sbjct: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234

Query: 237 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 295
           YIIANLGF D  L +   GGANV+GFQ+VD++  +V K ++RW  L+++EYPG+ T   K
Sbjct: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK 294

Query: 296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 355
           YTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV+++
Sbjct: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354

Query: 356 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR 415
           GL+GN++FD  G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+       GNDT+ +EN+
Sbjct: 355 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK 414

Query: 416 TVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGAR 475
           TVVVTTI+ESPYVM KKNHEM EGN++YEGYCVDLA+EIAKH G KYK+ IV DGKYGAR
Sbjct: 415 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGAR 474

Query: 476 DADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 535
           DADTKIWNGMVGELVYGKA+IAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG
Sbjct: 475 DADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 534

Query: 536 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGI 595
           VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEE EDG+E  S +  NEFGI
Sbjct: 535 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 594

Query: 596 FNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI 655
           FNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI
Sbjct: 595 FNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI 654

Query: 656 ESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARV 715
           ESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMWTYMRSAEPSVF RTTAEGVARV
Sbjct: 655 ESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARV 714

Query: 716 RKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKL 775
           RKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSSL   VNLAVLKL
Sbjct: 715 RKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKL 774

Query: 776 NEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIE 835
           +EQG+LDKLKNKWWYDKGECG+    SK+KTSALSLSNVAGVFYILVGGLGLAMLVALIE
Sbjct: 775 SEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIE 834

Query: 836 FCYKSRAEAKRMKVAKSAQTFNPTSSQNTQNLATYREGYNVYGTESIKI 884
           FCYKSRAEAKRMKVAK+AQ  NP+SSQN+QN ATY+EGYNVYG ES+KI
Sbjct: 835 FCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 883


>gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3 [Homo
           sapiens]
          Length = 836

 Score = 1313 bits (3399), Expect = 0.0
 Identities = 628/832 (75%), Positives = 736/832 (88%), Gaps = 5/832 (0%)

Query: 58  SEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISL 117
           S + F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC  LH+S 
Sbjct: 5   STSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSF 64

Query: 118 ITPSFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQN 177
           ITPSFPT+G   FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A + 
Sbjct: 65  ITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEK 124

Query: 178 GWHVSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVK 233
            W V+AI V N N    D  YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVK
Sbjct: 125 KWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVK 184

Query: 234 GYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP 293
           GYHYIIANLGF D  L +   GGANV+GFQ+VD++  +V K ++RW  L+++EYPG+ T 
Sbjct: 185 GYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTT 244

Query: 294 P-KYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQV 352
             KYTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV
Sbjct: 245 TIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQV 304

Query: 353 RIQGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAI 412
           +++GL+GN++FD  G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+       GNDT+ +
Sbjct: 305 QVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGL 364

Query: 413 ENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKY 472
           EN+TVVVTTI+ESPYVM KKNHEM EGN++YEGYCVDLA+EIAKH G KYK+ IV DGKY
Sbjct: 365 ENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKY 424

Query: 473 GARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 532
           GARDADTKIWNGMVGELVYGKA+IAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS
Sbjct: 425 GARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 484

Query: 533 KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNE 592
           KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEE EDG+E  S +  NE
Sbjct: 485 KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNE 544

Query: 593 FGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV 652
           FGIFNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV
Sbjct: 545 FGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV 604

Query: 653 SPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGV 712
           SPIESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMWTYMRSAEPSVF RTTAEGV
Sbjct: 605 SPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGV 664

Query: 713 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAV 772
           ARVRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSSL   VNLAV
Sbjct: 665 ARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAV 724

Query: 773 LKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVA 832
           LKL+EQG+LDKLKNKWWYDKGECG+    SK+KTSALSLSNVAGVFYILVGGLGLAMLVA
Sbjct: 725 LKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVA 784

Query: 833 LIEFCYKSRAEAKRMKVAKSAQTFNPTSSQNTQNLATYREGYNVYGTESIKI 884
           LIEFCYKSRAEAKRMKVAK+AQ  NP+SSQN+QN ATY+EGYNVYG ES+KI
Sbjct: 785 LIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 836


>gi|167001419 glutamate receptor, ionotropic, AMPA 1 isoform 1 [Homo
           sapiens]
          Length = 906

 Score = 1222 bits (3163), Expect = 0.0
 Identities = 593/838 (70%), Positives = 698/838 (83%), Gaps = 9/838 (1%)

Query: 13  SGFWGLAMGA-FPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNI 71
           +GF G  +GA FP+++QIGGLF     QE+ AFR A+       +    P  L+P +D +
Sbjct: 10  TGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFAL-------SQLTEPPKLLPQIDIV 62

Query: 72  ETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFV 131
             ++SF +T  FCSQ+S+GV+AIFG Y++R+V+ LTSFC ALH+  ITPSFP +  +QFV
Sbjct: 63  NISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFV 122

Query: 132 LQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFND 191
           LQLRP L+ AL+S++DHY+W  FV++YD DRG S+LQ +++ A +  W V+A+ +    +
Sbjct: 123 LQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTE 182

Query: 192 VSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLER 251
             YR L ++L++++E+  V+DCE ERL  IL QI+ + K+  GYHYI+ANLGF DI L +
Sbjct: 183 EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNK 242

Query: 252 FIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP-PKYTSALTYDGVLVMAE 310
           F   GANVTGFQLV++   +  K+M +WK  D R++   +   PKYTSALTYDGV VMAE
Sbjct: 243 FKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAE 302

Query: 311 TFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRV 370
            F+SLRRQ+IDISRRGNAGDCLANPA PWGQGID++R L+QVR +GLTGNVQF+  GRR 
Sbjct: 303 AFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRT 362

Query: 371 NYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIMESPYVMY 430
           NYT+ V E+K  G RK+GYWN+ DK V        G D ++++NRT +VTTI+E PYVM 
Sbjct: 363 NYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVML 422

Query: 431 KKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELV 490
           KKN   FEGND+YEGYCV+LA+EIAKH+G  Y++ IV DGKYGARD DTK WNGMVGELV
Sbjct: 423 KKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELV 482

Query: 491 YGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC 550
           YG+A++A+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC
Sbjct: 483 YGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC 542

Query: 551 IVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQG 610
           IVFAYIGVSVVLFLVSRFSPYEWH+EE E+G++  +    NEFGIFNSLWFSLGAFMQQG
Sbjct: 543 IVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQG 602

Query: 611 CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG 670
           CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG
Sbjct: 603 CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG 662

Query: 671 TLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTM 730
           TL++GSTKEFFRRSKIAV+EKMWTYM+SAEPSVF RTT EG+ RVRKSKGK+A+LLESTM
Sbjct: 663 TLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTM 722

Query: 731 NEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWY 790
           NEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+L N VNLAVLKLNEQGLLDKLKNKWWY
Sbjct: 723 NEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWWY 782

Query: 791 DKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMK 848
           DKGECGSGGGDSKDKTSALSLSNVAGVFYIL+GGLGLAMLVALIEFCYKSR+E+KRMK
Sbjct: 783 DKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 840


>gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2 [Homo
           sapiens]
          Length = 906

 Score = 1204 bits (3116), Expect = 0.0
 Identities = 585/838 (69%), Positives = 693/838 (82%), Gaps = 9/838 (1%)

Query: 13  SGFWGLAMGA-FPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNI 71
           +GF G  +GA FP+++QIGGLF     QE+ AFR A+       +    P  L+P +D +
Sbjct: 10  TGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFAL-------SQLTEPPKLLPQIDIV 62

Query: 72  ETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFV 131
             ++SF +T  FCSQ+S+GV+AIFG Y++R+V+ LTSFC ALH+  ITPSFP +  +QFV
Sbjct: 63  NISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFV 122

Query: 132 LQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFND 191
           LQLRP L+ AL+S++DHY+W  FV++YD DRG S+LQ +++ A +  W V+A+ +    +
Sbjct: 123 LQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTE 182

Query: 192 VSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLER 251
             YR L ++L++++E+  V+DCE ERL  IL QI+ + K+  GYHYI+ANLGF DI L +
Sbjct: 183 EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNK 242

Query: 252 FIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP-PKYTSALTYDGVLVMAE 310
           F   GANVTGFQLV++   +  K+M +WK  D R++   +   PKYTSALTYDGV VMAE
Sbjct: 243 FKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAE 302

Query: 311 TFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRV 370
            F+SLRRQ+IDISRRGNAGDCLANPA PWGQGID++R L+QVR +GLTGNVQF+  GRR 
Sbjct: 303 AFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRT 362

Query: 371 NYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIMESPYVMY 430
           NYT+ V E+K  G RK+GYWN+ DK V        G D ++++NRT +VTTI+E PYVM 
Sbjct: 363 NYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVML 422

Query: 431 KKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELV 490
           KKN   FEGND+YEGYCV+LA+EIAKH+G  Y++ IV DGKYGARD DTK WNGMVGELV
Sbjct: 423 KKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELV 482

Query: 491 YGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC 550
           YG+A++A+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC
Sbjct: 483 YGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC 542

Query: 551 IVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQG 610
           IVFAYIGVSVVLFLVSRFSPYEWH+EE E+G++  +    NEFGIFNSLWFSLGAFMQQG
Sbjct: 543 IVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQG 602

Query: 611 CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG 670
           CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG
Sbjct: 603 CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG 662

Query: 671 TLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTM 730
           TL++GSTKEFFRRSKIAV+EKMWTYM+SAEPSVF RTT EG+ RVRKSKGK+A+LLESTM
Sbjct: 663 TLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTM 722

Query: 731 NEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWY 790
           NEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+L   VNLAVLKL+EQG+LDKLK+KWWY
Sbjct: 723 NEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWY 782

Query: 791 DKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMK 848
           DKGECGS    SKDKTSALSLSNVAGVFYIL+GGLGLAMLVALIEFCYKSR+E+KRMK
Sbjct: 783 DKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 840


>gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3
           precursor [Homo sapiens]
          Length = 433

 Score =  857 bits (2213), Expect = 0.0
 Identities = 423/423 (100%), Positives = 423/423 (100%)

Query: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
           MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
Sbjct: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60

Query: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
           PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
Sbjct: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120

Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
           SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180

Query: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
           VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
Sbjct: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240

Query: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
           NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL
Sbjct: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300

Query: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
           TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
Sbjct: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360

Query: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
           VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT
Sbjct: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420

Query: 421 TIM 423
           TIM
Sbjct: 421 TIM 423


>gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3
           precursor [Homo sapiens]
          Length = 433

 Score =  857 bits (2213), Expect = 0.0
 Identities = 423/423 (100%), Positives = 423/423 (100%)

Query: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
           MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
Sbjct: 1   MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60

Query: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
           PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
Sbjct: 61  PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120

Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
           SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180

Query: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
           VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
Sbjct: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240

Query: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
           NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL
Sbjct: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300

Query: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
           TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
Sbjct: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360

Query: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
           VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT
Sbjct: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420

Query: 421 TIM 423
           TIM
Sbjct: 421 TIM 423


>gi|28416444 glutamate receptor, ionotropic, kainate 1 isoform 2
           precursor [Homo sapiens]
          Length = 905

 Score =  588 bits (1517), Expect = e-168
 Identities = 332/834 (39%), Positives = 490/834 (58%), Gaps = 36/834 (4%)

Query: 24  PSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPF---NLVPHVDNIETANSFAVT 80
           P  ++IGG+F    ++      LA     TS N +        L   +  I   +SF  +
Sbjct: 34  PQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEAS 93

Query: 81  NAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFP---TEGESQFVLQLRP- 136
              C Q + GV A+FG     SV  + S C+AL +  I   +     + +  F + L P 
Sbjct: 94  RRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPD 153

Query: 137 --SLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVSY 194
             ++  A+L L+ +Y W     +Y+   G   LQ +++   +    +    + + N  + 
Sbjct: 154 YAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDA- 212

Query: 195 RQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIH 254
           + LL+E+ + +E   + DC  E    IL+QI+ +G   + YHY    L    + LE + +
Sbjct: 213 KPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRY 272

Query: 255 GGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP-----PKYTSALTYDGVLVMA 309
            G N+TGF+L++ + P V  ++++W     +  P  ET          +AL YD V ++A
Sbjct: 273 SGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVA 332

Query: 310 ETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHY-GR 368
               S R  ++ +S          +   PW  G      +K+ R  GLTG++ F+   G 
Sbjct: 333 --IASHRASQLTVS------SLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGL 384

Query: 369 RVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQ-DVPTLGNDTAAIENRTVVVTTIMESPY 427
           R ++ +D+  LK  G  K+G WN    L +   +     N T ++ NRT++VTTI+E PY
Sbjct: 385 RKDFDLDIISLKEEGTEKIGIWNSNSGLNMTDSNKDKSSNITDSLANRTLIVTTILEEPY 444

Query: 428 VMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVG 487
           VMY+K+ +   GND++EGYC+DL  E++  +G  Y + +VPDGKYGA++ D   WNGMV 
Sbjct: 445 VMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQN-DKGEWNGMVK 503

Query: 488 ELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEI 547
           EL+  +A++A+APLTIT VRE+VIDFSKPFM+LGISI+ +KP  + PGVFSFL+PL+ +I
Sbjct: 504 ELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDI 563

Query: 548 WMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFM 607
           WM ++ A +GVS VLF+++RF+PYEW+   P +     SD   N F + NS WF +GA M
Sbjct: 564 WMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPD---SDVVENNFTLLNSFWFGVGALM 620

Query: 608 QQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEI 667
           QQG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFLTVERM SPI+SA+DLAKQT+I
Sbjct: 621 QQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKI 680

Query: 668 AYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLE 727
            YG +  GST  FF++SKI+ YEKMW +M S + +   R + EG+ RV  +   +A L+E
Sbjct: 681 EYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTT--DYALLME 738

Query: 728 STMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGLLDKLKNK 787
           ST  EY+ QR  C+  ++GG +DSKGYGV TP GS   + + +A+L+L E+G L  +K K
Sbjct: 739 STSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEK 797

Query: 788 WWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 841
           WW   G C     +   + SAL + N+ G+F +L  GL L++ VA+ EF YKSR
Sbjct: 798 WWRGNG-CPE---EDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSR 847


>gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1
           precursor [Homo sapiens]
          Length = 908

 Score =  586 bits (1511), Expect = e-167
 Identities = 340/868 (39%), Positives = 498/868 (57%), Gaps = 47/868 (5%)

Query: 3   IISRQIVLLFSGFW-GLAMGAFPSSVQIGGLF----IRNTDQEYTAFRLAIFLHNTS--- 54
           +  R + LL    W G + G     ++ GG+F          E  AFR A+   N +   
Sbjct: 12  VFRRTVKLLLCLLWIGYSQGT-THVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTL 70

Query: 55  -PNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSAL 113
            PN +     L      I   +SF  +   C Q S GV AIFG     S + + S C+AL
Sbjct: 71  LPNTT-----LTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNAL 125

Query: 114 ---HISLITPSFPTEGESQFVLQLRP---SLRGALLSLLDHYEWNCFVFLYDTDRGYSIL 167
              HI        ++ +  F + L P   SL  A+L L+  ++W     +YD   G   L
Sbjct: 126 GVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRL 185

Query: 168 QAIMEKAGQNGWHVSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVS 227
           Q +++   +    +  I     +    + LL+E+ R +E   + DC  E    IL+Q ++
Sbjct: 186 QELIKAPSRYNLRLK-IRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALA 244

Query: 228 VGKHVKGYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRW--KKLDQR 285
           +G   + YHYI   L    + +E + + G N+TGF++++     V  ++++W  ++L   
Sbjct: 245 MGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAP 304

Query: 286 EYPGSETPPKYTS---ALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQG 342
             P S     + +   AL YD V V++   +   +  +   +         N   PW  G
Sbjct: 305 PKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQ--------CNRHKPWRFG 356

Query: 343 IDMERTLKQVRIQGLTGNVQFDHY-GRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQD 401
                 +K+   +GLTG + F+   G R ++ +DV  LK  G  K+G W+    L + + 
Sbjct: 357 TRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTES 416

Query: 402 VPTL-GNDTAAIENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGI 460
                 N T ++ NR+++VTTI+E PYV++KK+ +   GND++EGYC+DL  E++  +G 
Sbjct: 417 QKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGF 476

Query: 461 KYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSL 520
            Y+I +V DGKYGA+D     WNGMV EL+  KA++A+APL IT VRE+VIDFSKPFM+L
Sbjct: 477 TYEIRLVEDGKYGAQDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTL 536

Query: 521 GISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPED 580
           GISI+ +KP  + PGVFSFL+PL+ +IWM I+ AY+GVS VLF+++RFSPYEW+   P  
Sbjct: 537 GISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHP-- 594

Query: 581 GKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTA 640
                SD   N F + NS WF +GA MQQG ++ P++LS RIVGG+WWFFTLIIISSYTA
Sbjct: 595 -CNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTA 653

Query: 641 NLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAE 700
           NLAAFLTVERM SPI+SA+DLAKQT+I YG ++ G+T  FF++SKI+ Y+KMW +M S  
Sbjct: 654 NLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRR 713

Query: 701 PSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPK 760
            SV  ++  EG+ RV  S   +AFL+EST  E++ QR  C+  ++GG +DSKGYGV TP 
Sbjct: 714 QSVLVKSNEEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPM 770

Query: 761 GSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYI 820
           GS   + + +A+L+L E+G L  +K KWW   G C     +   + SAL + N+ G+F +
Sbjct: 771 GSPYRDKITIAILQLQEEGKLHMMKEKWWRGNG-CPE---EESKEASALGVQNIGGIFIV 826

Query: 821 LVGGLGLAMLVALIEFCYKSRAEAKRMK 848
           L  GL L++ VA+ EF YKS+  A+  K
Sbjct: 827 LAAGLVLSVFVAVGEFLYKSKKNAQLEK 854


>gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2
           precursor [Homo sapiens]
          Length = 869

 Score =  586 bits (1511), Expect = e-167
 Identities = 340/868 (39%), Positives = 498/868 (57%), Gaps = 47/868 (5%)

Query: 3   IISRQIVLLFSGFW-GLAMGAFPSSVQIGGLF----IRNTDQEYTAFRLAIFLHNTS--- 54
           +  R + LL    W G + G     ++ GG+F          E  AFR A+   N +   
Sbjct: 12  VFRRTVKLLLCLLWIGYSQGT-THVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTL 70

Query: 55  -PNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSAL 113
            PN +     L      I   +SF  +   C Q S GV AIFG     S + + S C+AL
Sbjct: 71  LPNTT-----LTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNAL 125

Query: 114 ---HISLITPSFPTEGESQFVLQLRP---SLRGALLSLLDHYEWNCFVFLYDTDRGYSIL 167
              HI        ++ +  F + L P   SL  A+L L+  ++W     +YD   G   L
Sbjct: 126 GVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRL 185

Query: 168 QAIMEKAGQNGWHVSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVS 227
           Q +++   +    +  I     +    + LL+E+ R +E   + DC  E    IL+Q ++
Sbjct: 186 QELIKAPSRYNLRLK-IRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALA 244

Query: 228 VGKHVKGYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRW--KKLDQR 285
           +G   + YHYI   L    + +E + + G N+TGF++++     V  ++++W  ++L   
Sbjct: 245 MGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAP 304

Query: 286 EYPGSETPPKYTS---ALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQG 342
             P S     + +   AL YD V V++   +   +  +   +         N   PW  G
Sbjct: 305 PKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQ--------CNRHKPWRFG 356

Query: 343 IDMERTLKQVRIQGLTGNVQFDHY-GRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQD 401
                 +K+   +GLTG + F+   G R ++ +DV  LK  G  K+G W+    L + + 
Sbjct: 357 TRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTES 416

Query: 402 VPTL-GNDTAAIENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGI 460
                 N T ++ NR+++VTTI+E PYV++KK+ +   GND++EGYC+DL  E++  +G 
Sbjct: 417 QKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGF 476

Query: 461 KYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSL 520
            Y+I +V DGKYGA+D     WNGMV EL+  KA++A+APL IT VRE+VIDFSKPFM+L
Sbjct: 477 TYEIRLVEDGKYGAQDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTL 536

Query: 521 GISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPED 580
           GISI+ +KP  + PGVFSFL+PL+ +IWM I+ AY+GVS VLF+++RFSPYEW+   P  
Sbjct: 537 GISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHP-- 594

Query: 581 GKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTA 640
                SD   N F + NS WF +GA MQQG ++ P++LS RIVGG+WWFFTLIIISSYTA
Sbjct: 595 -CNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTA 653

Query: 641 NLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAE 700
           NLAAFLTVERM SPI+SA+DLAKQT+I YG ++ G+T  FF++SKI+ Y+KMW +M S  
Sbjct: 654 NLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRR 713

Query: 701 PSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPK 760
            SV  ++  EG+ RV  S   +AFL+EST  E++ QR  C+  ++GG +DSKGYGV TP 
Sbjct: 714 QSVLVKSNEEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPM 770

Query: 761 GSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYI 820
           GS   + + +A+L+L E+G L  +K KWW   G C     +   + SAL + N+ G+F +
Sbjct: 771 GSPYRDKITIAILQLQEEGKLHMMKEKWWRGNG-CPE---EESKEASALGVQNIGGIFIV 826

Query: 821 LVGGLGLAMLVALIEFCYKSRAEAKRMK 848
           L  GL L++ VA+ EF YKS+  A+  K
Sbjct: 827 LAAGLVLSVFVAVGEFLYKSKKNAQLEK 854


>gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor
           [Homo sapiens]
          Length = 919

 Score =  585 bits (1508), Expect = e-167
 Identities = 335/862 (38%), Positives = 503/862 (58%), Gaps = 52/862 (6%)

Query: 10  LLFSGFWGLAMGAFPSSVQIGGLF---------IRNTDQEYTAFRLAIFLHNTS--PNAS 58
           LL   FW       P  ++IGG+F         + N ++    F   I   N +  PN +
Sbjct: 19  LLVCAFWIPDSRGMPHVIRIGGIFEYADGPNAQVMNAEEHAFRFSANIINRNRTLLPNTT 78

Query: 59  EAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSAL---HI 115
                L   +  I   +SF  T   C Q + GV AIFG       + + S C+AL   HI
Sbjct: 79  -----LTYDIQRIHFHDSFEATKKACDQLALGVVAIFGPSQGSCTNAVQSICNALEVPHI 133

Query: 116 SLITPSFPTEGESQFVLQLRP---SLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIME 172
            L     P + +  F + L P   SL  A+L L+ + +W     +YD   G   LQ ++ 
Sbjct: 134 QLRWKHHPLDNKDTFYVNLYPDYASLSHAILDLVQYLKWRSATVVYDDSTGLIRLQELIM 193

Query: 173 KAGQNGWHVSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHV 232
              +    +    +   +D S R LL+E+ R +E + + DC       IL+Q +++G   
Sbjct: 194 APSRYNIRLKIRQLPIDSDDS-RPLLKEMKRGREFRIIFDCSHTMAAQILKQAMAMGMMT 252

Query: 233 KGYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSET 292
           + YH+I   L    + LE + + G N+TGF++++ + P V  ++++W     +  P SE+
Sbjct: 253 EYYHFIFTTLDLYALDLEPYRYSGVNLTGFRILNVDNPHVSAIVEKWSMERLQAAPRSES 312

Query: 293 P-----PKYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMER 347
                     +AL YD V +++  ++   +  +      N+  C  + A  W  G     
Sbjct: 313 GLLDGVMMTDAALLYDAVHIVSVCYQRAPQMTV------NSLQCHRHKA--WRFGGRFMN 364

Query: 348 TLKQVRIQGLTGNVQFDHY-GRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLG 406
            +K+ + +GLTG + F+   G R ++ +D+  LK  G  KVG W+  D L + +     G
Sbjct: 365 FIKEAQWEGLTGRIVFNKTSGLRTDFDLDIISLKEDGLEKVGVWSPADGLNITEVAKGRG 424

Query: 407 -NDTAAIENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIA 465
            N T ++ NR+++VTT++E P+VM++K+     GND++EGYC+DL  E+A  +G  Y+I 
Sbjct: 425 PNVTDSLTNRSLIVTTVLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIR 484

Query: 466 IVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIM 525
           +V DGKYGA+D D   WNGMV EL+  KA++A+APLTIT VRE+ IDFSKPFM+LG+SI+
Sbjct: 485 LVEDGKYGAQD-DKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSIL 543

Query: 526 IKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGP 585
            +KP  + P VFSFL+PL+ +IWM ++ AY+GVS VLF+++RFSPYEW+   P +     
Sbjct: 544 YRKPNGTNPSVFSFLNPLSPDIWMYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPG--- 600

Query: 586 SDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAF 645
           S+   N F + NS WF +G+ MQQG ++ P++LS RI+GG+WWFFTLIIISSYTANLAAF
Sbjct: 601 SEVVENNFTLLNSFWFGMGSLMQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLAAF 660

Query: 646 LTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFT 705
           LTVERM SPI+SA+DLAKQT+I YG +  G+T  FF++SKI+ +EKMW +M S++PS   
Sbjct: 661 LTVERMESPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFM-SSKPSALV 719

Query: 706 RTTAEGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLG 765
           +   EG+ R   +   +A L+EST  EY+ QR  C+  ++GG +DSKGYG+ TP GS   
Sbjct: 720 KNNEEGIQRALTA--DYALLMESTTIEYVTQRN-CNLTQIGGLIDSKGYGIGTPMGSPYR 776

Query: 766 NAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDK-TSALSLSNVAGVFYILVGG 824
           + + +A+L+L E+  L  +K KWW      GSG  + ++K  SAL +  + G+F +L  G
Sbjct: 777 DKITIAILQLQEEDKLHIMKEKWWR-----GSGCPEEENKEASALGIQKIGGIFIVLAAG 831

Query: 825 LGLAMLVALIEFCYKSRAEAKR 846
           L L++LVA+ EF YK R  A+R
Sbjct: 832 LVLSVLVAVGEFVYKLRKTAER 853


>gi|4504117 glutamate receptor, ionotropic, kainate 1 isoform 1
           precursor [Homo sapiens]
          Length = 918

 Score =  579 bits (1493), Expect = e-165
 Identities = 332/849 (39%), Positives = 491/849 (57%), Gaps = 51/849 (6%)

Query: 24  PSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPF---NLVPHVDNIETANSFAVT 80
           P  ++IGG+F    ++      LA     TS N +        L   +  I   +SF  +
Sbjct: 34  PQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEAS 93

Query: 81  NAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFP---TEGESQFVLQLRP- 136
              C Q + GV A+FG     SV  + S C+AL +  I   +     + +  F + L P 
Sbjct: 94  RRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPD 153

Query: 137 --SLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVSY 194
             ++  A+L L+ +Y W     +Y+   G   LQ +++   +    +    + + N  + 
Sbjct: 154 YAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDA- 212

Query: 195 RQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIH 254
           + LL+E+ + +E   + DC  E    IL+QI+ +G   + YHY    L    + LE + +
Sbjct: 213 KPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRY 272

Query: 255 GGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP-----PKYTSALTYDGVLVMA 309
            G N+TGF+L++ + P V  ++++W     +  P  ET          +AL YD V ++A
Sbjct: 273 SGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVA 332

Query: 310 ETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHY-GR 368
               S R  ++ +S          +   PW  G      +K+ R  GLTG++ F+   G 
Sbjct: 333 --IASHRASQLTVS------SLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGL 384

Query: 369 RVNYTMDVFELKSTGP---------------RKVGYWNDMDKLVLIQ-DVPTLGNDTAAI 412
           R ++ +D+  LK  G                +K+G WN    L +   +     N T ++
Sbjct: 385 RKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTDSNKDKSSNITDSL 444

Query: 413 ENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKY 472
            NRT++VTTI+E PYVMY+K+ +   GND++EGYC+DL  E++  +G  Y + +VPDGKY
Sbjct: 445 ANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKY 504

Query: 473 GARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 532
           GA++ D   WNGMV EL+  +A++A+APLTIT VRE+VIDFSKPFM+LGISI+ +KP  +
Sbjct: 505 GAQN-DKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGT 563

Query: 533 KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNE 592
            PGVFSFL+PL+ +IWM ++ A +GVS VLF+++RF+PYEW+   P +     SD   N 
Sbjct: 564 NPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPD---SDVVENN 620

Query: 593 FGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV 652
           F + NS WF +GA MQQG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFLTVERM 
Sbjct: 621 FTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERME 680

Query: 653 SPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGV 712
           SPI+SA+DLAKQT+I YG +  GST  FF++SKI+ YEKMW +M S + +   R + EG+
Sbjct: 681 SPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGI 740

Query: 713 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAV 772
            RV  +   +A L+EST  EY+ QR  C+  ++GG +DSKGYGV TP GS   + + +A+
Sbjct: 741 QRVLTT--DYALLMESTSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAI 797

Query: 773 LKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVA 832
           L+L E+G L  +K KWW   G C     +   + SAL + N+ G+F +L  GL L++ VA
Sbjct: 798 LQLQEEGKLHMMKEKWWRGNG-CPE---EDNKEASALGVENIGGIFIVLAAGLVLSVFVA 853

Query: 833 LIEFCYKSR 841
           + EF YKSR
Sbjct: 854 IGEFIYKSR 862


>gi|29029597 glutamate receptor KA2 precursor [Homo sapiens]
          Length = 980

 Score =  499 bits (1285), Expect = e-141
 Identities = 304/830 (36%), Positives = 454/830 (54%), Gaps = 54/830 (6%)

Query: 45  RLAIFLHNTSPNAS-EAPFNLVPHVD--NIETANSFAVTNAFCSQYSRGVFAIFGLYDK- 100
           RLA+ L     N   E P      VD   ++  + +  T+  C    +GV ++ G     
Sbjct: 41  RLALALAREQINGIIEVPAKARVEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSP 100

Query: 101 RSVHTLTSFCSALHISLITPSFPTEGESQFV----LQLRPSLRGALLS---LLDHYEW-- 151
            S  T++  C    I  I          Q++    + L PS     L+   +L  + +  
Sbjct: 101 ASASTVSHICGEKEIPHIKVGPEETPRLQYLRFASVSLYPSNEDVSLAVSRILKSFNYPS 160

Query: 152 --------NCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVSYRQLLEELDR 203
                    C + L +  RG+ I +  +          S   +++  D +   LL+E+  
Sbjct: 161 ASLICAKAECLLRLEELVRGFLISKETL----------SVRMLDDSRDPT--PLLKEIRD 208

Query: 204 RQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIHGGANVTGFQ 263
            +    +ID        IL +   +G     Y YI+  + F  + L+  +   +N+ GF 
Sbjct: 209 DKVSTIIIDANASISHLILRKASELGMTSAFYKYILTTMDFPILHLDGIVEDSSNILGFS 268

Query: 264 LVDFNTPMVIKLMDRWKKLDQREYPGSET--PPKYTSALTYDGVLVMAETFRSLRRQKID 321
           + + + P   + + R   +  RE   + T   P  ++AL +D V V+    R L R    
Sbjct: 269 MFNTSHPFYPEFV-RSLNMSWRENCEASTYLGPALSAALMFDAVHVVVSAVRELNR---- 323

Query: 322 ISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVNYTMDVFELKS 381
            S+           A  W  G  +   L+ V   GLTG V+F+  G+R NYT+ + E   
Sbjct: 324 -SQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKSR 382

Query: 382 TGPRKVGYWNDMDKLVLIQDVPTLG-NDTAAIENRTVVVTTIMESPYVMYKKNHEMFEGN 440
            G R++G W       L  +  TL  N +  + N+T+VVTTI+E+PYVM + N +   GN
Sbjct: 383 QGHREIGVW--YSNRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALSGN 440

Query: 441 DKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAP 500
           +++EG+CVD+  E+A+ +  +Y++ +V DG YGA + +   W GMVGEL+  KA++A+A 
Sbjct: 441 ERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGAPEPNGS-WTGMVGELINRKADLAVAA 499

Query: 501 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 560
            TIT  RE+VIDFSKPFM+LGISI+ +     KPG FSFLDP +  +W+ ++ AY+ VS 
Sbjct: 500 FTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSC 559

Query: 561 VLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSG 620
           VLFL +R SPYEW+   P            N++ + NSLWF +G FMQQG +I PR+LS 
Sbjct: 560 VLFLAARLSPYEWYNPHP--CLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALST 617

Query: 621 RIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEF 680
           R V GVWW FTLIIISSYTANLAAFLTV+RM  P+ESA+DLA QT I YGT+ +GST  F
Sbjct: 618 RCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTF 677

Query: 681 FRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYIEQRKPC 740
           F+ S+   Y++MW YM+S +PSVF ++T EG+ARV  S  ++AFLLESTMNEY  +R  C
Sbjct: 678 FQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVLNS--RYAFLLESTMNEY-HRRLNC 734

Query: 741 DTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGG 800
           +  ++GG LD+KGYG+  P GS   + + LA+L+L E   L+ LK KWW + G C     
Sbjct: 735 NLTQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEILKRKWW-EGGRCPK--- 790

Query: 801 DSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVA 850
           +   +   L + N+ G+F +L+ GL +A+ VA++EF + +R  A+  +V+
Sbjct: 791 EEDHRAKGLGMENIGGIFIVLICGLIIAVFVAVMEFIWSTRRSAESEEVS 840


>gi|29029595 glutamate receptor KA1 precursor [Homo sapiens]
          Length = 956

 Score =  496 bits (1277), Expect = e-140
 Identities = 275/665 (41%), Positives = 396/665 (59%), Gaps = 26/665 (3%)

Query: 197 LLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIHGG 256
           LL+E+   +    +I         IL +   +G     Y YI  NL F    ++  +   
Sbjct: 203 LLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNLEFSLQRMDSLVDDR 262

Query: 257 ANVTGFQLVD----FNTPMVIKLMDRWKK-LDQREYPGSETPPKYTSALTYDGVLVMAET 311
            N+ GF + +    F       L   W++  D   + G    P  +SAL +D V  +   
Sbjct: 263 VNILGFSIFNQSHAFFQEFAQSLNQSWQENCDHVPFTG----PALSSALLFDAVYAVVTA 318

Query: 312 FRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVN 371
            + L R     S+           A  W  G  +   L+ V ++GLTG+++F+  G+R N
Sbjct: 319 VQELNR-----SQEIGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLTGHIEFNSKGQRSN 373

Query: 372 YTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIMESPYVMYK 431
           Y + + +    G R++G W+  + L +   +    N +  + N T+VVTTI+E+PY+M K
Sbjct: 374 YALKILQFTRNGFRQIGQWHVAEGLSMDSHLYA-SNISDTLFNTTLVVTTILENPYLMLK 432

Query: 432 KNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELVY 491
            NH+  EGND+YEG+CVD+  E+A+ +   YKI +V DG YG  +A+   W GMVGEL+ 
Sbjct: 433 GNHQEMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPEANGT-WTGMVGELIA 491

Query: 492 GKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCI 551
            KA++A+A LTIT  RE+VIDFSKPFM+LGISI+ +     KPG FSFLDP +  +W+ +
Sbjct: 492 RKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPGVWLFM 551

Query: 552 VFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGC 611
           + AY+ VS VLFLV+R +PYEW++  P    +G  +   N++ + NSLWF +G FMQQG 
Sbjct: 552 LLAYLAVSCVLFLVARLTPYEWYSPHP--CAQGRCNLLVNQYSLGNSLWFPVGGFMQQGS 609

Query: 612 DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGT 671
            I+PR+LS R V GVWW FTLIIISSYTANLAAFLTV+RM  PIES +DLA QT I YGT
Sbjct: 610 TIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDVPIESVDDLADQTAIEYGT 669

Query: 672 LDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMN 731
           +  GS+  FF+ S+   Y++MW YM S +PSVF ++T EG+ARV  S   +AFLLESTMN
Sbjct: 670 IHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNS--NYAFLLESTMN 727

Query: 732 EYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYD 791
           EY  QR  C+  ++GG LD+KGYG+  P GS   +  +LA+L+L E   L+ LK KWW +
Sbjct: 728 EYYRQRN-CNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILKRKWW-E 785

Query: 792 KGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR-AEAKRMKVA 850
            G+C     +   +   L + N+ G+F +L+ GL +A+ +A++EF +  R +EA  + V 
Sbjct: 786 GGKCPK---EEDHRAKGLGMENIGGIFVVLICGLIVAIFMAMLEFLWTLRHSEATEVSVC 842

Query: 851 KSAQT 855
           +   T
Sbjct: 843 QEMVT 847


>gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens]
          Length = 1007

 Score =  337 bits (863), Expect = 4e-92
 Identities = 237/867 (27%), Positives = 412/867 (47%), Gaps = 83/867 (9%)

Query: 25  SSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFC 84
           S + IG +F  +  ++   FR A+   N +    +    +   V  ++  N F      C
Sbjct: 25  SIIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTE-KITFSVTFVDGNNPFQAVQEAC 83

Query: 85  SQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLI-----TPSFPTEG--------ESQFV 131
              ++G+ A+       S  +L S   A+HI  +     T   P  G           + 
Sbjct: 84  ELMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYT 143

Query: 132 LQLRPS--LRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENF 189
           L +RP   L   +L ++  Y W  F+  YD++     +Q  ++K  Q G  V+   VEN 
Sbjct: 144 LSVRPPVYLHDVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKVENN 203

Query: 190 NDVSYRQL-----LEELDRRQE--KKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
            +     L     +EEL+R ++  ++ ++       ++ + ++V         H+II N 
Sbjct: 204 INKMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFITEVVETNLVAFDCHWIIINE 263

Query: 243 GFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPK------- 295
              D+ ++  +    ++    ++    P+   +  R  + + R    +   PK       
Sbjct: 264 EINDVDVQELVR--RSIGRLTIIRQTFPVPQNISQRCFRGNHR-ISSTLCDPKDPFAQNM 320

Query: 296 -YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRI 354
             ++   YD VL++A  F      +   S    +  C+   + PW  G  M  T+K+  +
Sbjct: 321 EISNLYIYDTVLLLANAFHKKLEDRKWHSMASLS--CIRKNSKPWQGGRSMLETIKKGGV 378

Query: 355 QGLTGNVQFDHYGRRVNYTMDVF-----ELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDT 409
            GLTG ++F   G   N   ++      E    G RK+G WN +  L        L N+ 
Sbjct: 379 SGLTGELEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKKLENNM 438

Query: 410 AAIENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPD 469
             +  R V   T++E P+VM  +N  +     KY+G+ +D+   ++ ++G  Y+I + PD
Sbjct: 439 RGVVLRVV---TVLEEPFVMVSEN--VLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPD 493

Query: 470 GKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKP 529
            KYG+   D   WNG+VGELV+ +A+I I+ LTIT  RE V+DF+  +M   + +++++ 
Sbjct: 494 HKYGSPQEDGT-WNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRRA 552

Query: 530 QKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQP 589
           +K+   +F+ L P    +W CI    + V ++++L++  +P                  P
Sbjct: 553 EKTVD-MFACLAPFDLSLWACIAGTVLLVGLLVYLLNWLNP------------------P 593

Query: 590 PNEFG------IFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLA 643
             + G      ++NS+WF  G+F+QQG ++   +L+ R++ G WW F LI+ISSYTANLA
Sbjct: 594 RLQMGSMTSTTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLA 653

Query: 644 AFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKI------AVYEKMWTYMR 697
           AFLT+ R+ S I+S +DL+KQTEI YGT+   +  E  R   +      ++Y +MW  + 
Sbjct: 654 AFLTITRIESSIQSLQDLSKQTEIPYGTVLDSAVYEHVRMKGLNPFERDSMYSQMWRMIN 713

Query: 698 SAEPSVFTRTTAEGVARVRKSK-GKFAFLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYG 755
            +  S       E  A ++K K G +AF+ ++ + EY+    P C    +G  +  +GYG
Sbjct: 714 RSNGS--ENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTIGNTVADRGYG 771

Query: 756 VATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECG-SGGGDSKDKTSALSLSNV 814
           +A   GS   +  +  +L+L + G +D LK+KWW   G+C      D+K K  AL + + 
Sbjct: 772 IALQHGSPYRDVFSQRILELQQNGDMDILKHKWWPKNGQCDLYSSVDTKQKGGALDIKSF 831

Query: 815 AGVFYILVGGLGLAMLVALIEFCYKSR 841
           AGVF IL  G+ L+  +A++E  +  R
Sbjct: 832 AGVFCILAAGIVLSCFIAMLETWWNKR 858


>gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [Homo
           sapiens]
          Length = 1009

 Score =  332 bits (852), Expect = 7e-91
 Identities = 245/864 (28%), Positives = 404/864 (46%), Gaps = 76/864 (8%)

Query: 25  SSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFC 84
           S + IG +F  N  ++   F+LA+   + + +  ++   +   +  IE  N F      C
Sbjct: 22  SIIHIGAIFEENAAKDDRVFQLAVSDLSLNDDILQSE-KITYSIKVIEANNPFQAVQEAC 80

Query: 85  SQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFVLQLRPS------- 137
              ++G+ A+       S + L S   A+HI  +       G  +    L PS       
Sbjct: 81  DLMTQGILALVTSTGCASANALQSLTDAMHIPHLFVQRNPGGSPRTACHLNPSPDGEAYT 140

Query: 138 --------LRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVEN- 188
                   L   +L L+    W  FV  YD++     LQ+ +++A + G  VS   V+  
Sbjct: 141 LASRPPVRLNDVMLRLVTELRWQKFVMFYDSEYDIRGLQSFLDQASRLGLDVSLQKVDKN 200

Query: 189 ----FNDVSYRQLLEELDRRQE--KKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
               F  +      EEL+R ++  ++ ++    +   + + + V      K  H++  N 
Sbjct: 201 ISHVFTSLFTTMKTEELNRYRDTLRRAILLLSPQGAHSFINEAVETNLASKDSHWVFVNE 260

Query: 243 GFKDISLERFIHGGA-----------NVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSE 291
              D  +   +H              +    Q    N   +  L+      D +E  G  
Sbjct: 261 EISDPEILDLVHSALGRMTVVRQIFPSAKDNQKCTRNNHRISSLL-----CDPQE--GYL 313

Query: 292 TPPKYTSALTYDGVLVMAETF-RSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLK 350
              + ++   YD VL++A  F R L  +K       N   C+     PW  G  M  T+K
Sbjct: 314 QMLQISNLYLYDSVLMLANAFHRKLEDRKWHSMASLN---CIRKSTKPWNGGRSMLDTIK 370

Query: 351 QVRIQGLTGNVQFDHYGRRVNYTMDVF-----ELKSTGPRKVGYWNDMDKLVLIQDVPTL 405
           +  I GLTG ++F           ++      E      RK+  W+    L        +
Sbjct: 371 KGHITGLTGVMEFREDSSNPYVQFEILGTTYSETFGKDMRKLATWDSEKGLNGSLQERPM 430

Query: 406 GNDTAAIENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIA 465
           G+    ++  T+ V T++E P+VM  +N  +     +Y+G+ +D+   +AK +G KY+I 
Sbjct: 431 GS---RLQGLTLKVVTVLEEPFVMVAEN--ILGQPKRYKGFSIDVLDALAKALGFKYEIY 485

Query: 466 IVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIM 525
             PDG+YG +  +T  WNGM+GEL+  +A++AI+ +TIT  RE V+DFSK +M   + I+
Sbjct: 486 QAPDGRYGHQLHNTS-WNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYSVGIL 544

Query: 526 IKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGP 585
           IKKP++ K  +FS   P  + +W CI  A   V V++F+++R              +   
Sbjct: 545 IKKPEE-KISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVR--------AQSAA 595

Query: 586 SDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAF 645
             +P     + +++W   GAF+QQG + S  S++ RIV G WW FTLI+ SSYTANLAAF
Sbjct: 596 QPRPSASATLHSAIWIVYGAFVQQGGESSVNSMAMRIVMGSWWLFTLIVCSSYTANLAAF 655

Query: 646 LTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRR------SKIAVYEKMW-TYMRS 698
           LTV RM +PI + +DL+KQ E++YGT+   +  E+FR        + + + ++W T  ++
Sbjct: 656 LTVSRMDNPIRTFQDLSKQVEMSYGTVRDSAVYEYFRAKGTNPLEQDSTFAELWRTISKN 715

Query: 699 AEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYIE-QRKPCDTMKVGGNLDSKGYGVA 757
                   + +EG+ + +  KG +AFL +  + EY       C    +G ++ SKGYG+A
Sbjct: 716 GGADNCVSSPSEGIRKAK--KGNYAFLWDVAVVEYAALTDDDCSVTVIGNSISSKGYGIA 773

Query: 758 TPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECG-SGGGDSKDKTSALSLSNVAG 816
              GS   +  +  +L+L + G LD LK KWW   G C  +    ++    +L L + AG
Sbjct: 774 LQHGSPYRDLFSQRILELQDTGDLDVLKQKWWPHMGRCDLTSHASAQADGKSLKLHSFAG 833

Query: 817 VFYILVGGLGLAMLVALIEFCYKS 840
           VF IL  GL LA LVA +E  + S
Sbjct: 834 VFCILAIGLLLACLVAALELWWNS 857


>gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens]
          Length = 885

 Score =  221 bits (564), Expect = 2e-57
 Identities = 177/631 (28%), Positives = 300/631 (47%), Gaps = 85/631 (13%)

Query: 295 KYTSALTYDGVLVMAETFRSL-RRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVR 353
           K  SA   D V V+A+    L  ++ I    RG    C+ N    W  G   +R L   +
Sbjct: 275 KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329

Query: 354 I-QGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAI 412
              G+TG V+F+  G R      +  L++    +VG +N    +   + +   G +T   
Sbjct: 330 YADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKP 389

Query: 413 E----NRTVVVTTIMESPYVMYKKNHEMFEGNDKYE------------------------ 444
                +  + + TI + P+V  K    + +G  K E                        
Sbjct: 390 RGYQMSTRLKIVTIHQEPFVYVKPT--LSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSP 447

Query: 445 ---------GYCVDLASEIAKHIGIKYKIAIVPDGKYGARD----ADTKIWNGMVGELVY 491
                    G+C+DL  ++A+ +   Y++ +V DGK+G ++    ++ K WNGM+GEL+ 
Sbjct: 448 RHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLS 507

Query: 492 GKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCI 551
           G+A++ +APLTI   R + I+FSKPF   G++I++KK +  +  + SF+ P    +W+ +
Sbjct: 508 GQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLV 566

Query: 552 VFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGC 611
             +   V+V+L+L+ RFSP+       E+ +E       +   + +++WFS G  +  G 
Sbjct: 567 GLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEE-------DALTLSSAMWFSWGVLLNSGI 619

Query: 612 -DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EI 667
            + +PRS S RI+G VW  F +II++SYTANLAAFL ++R    I    D   +    + 
Sbjct: 620 GEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKF 679

Query: 668 AYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLE 727
            Y T+   S   +FRR       ++ T  R  E   +  + AE +  VR +K   AF+ +
Sbjct: 680 IYATVKQSSVDIYFRRQ-----VELSTMYRHMEKHNY-ESAAEAIQAVRDNK-LHAFIWD 732

Query: 728 STMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGLLDKLKNK 787
           S + E+ E  + CD +  G      G+G+   K S     V+L++LK +E G ++ L +K
Sbjct: 733 SAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDL-DK 790

Query: 788 WWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRM 847
            W    EC S      +  + L+  N+AGVF ++ GG+   + +  IE  YK   +A+R 
Sbjct: 791 TWVRYQECDS----RSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRK 846

Query: 848 KV----------AKSAQTFNPTSSQNTQNLA 868
           ++           K+ Q ++PT      NL+
Sbjct: 847 QMQLAFAAVNVWRKNLQQYHPTDITGPLNLS 877


>gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens]
          Length = 938

 Score =  218 bits (556), Expect = 2e-56
 Identities = 171/602 (28%), Positives = 290/602 (48%), Gaps = 75/602 (12%)

Query: 295 KYTSALTYDGVLVMAETFRSL-RRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVR 353
           K  SA   D V V+A+    L  ++ I    RG    C+ N    W  G   +R L   +
Sbjct: 275 KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329

Query: 354 I-QGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAI 412
              G+TG V+F+  G R      +  L++    +VG +N    +   + +   G +T   
Sbjct: 330 YADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKP 389

Query: 413 E----NRTVVVTTIMESPYVMYKKNHEMFEGNDKYE------------------------ 444
                +  + + TI + P+V  K    + +G  K E                        
Sbjct: 390 RGYQMSTRLKIVTIHQEPFVYVKPT--LSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSP 447

Query: 445 ---------GYCVDLASEIAKHIGIKYKIAIVPDGKYGARD----ADTKIWNGMVGELVY 491
                    G+C+DL  ++A+ +   Y++ +V DGK+G ++    ++ K WNGM+GEL+ 
Sbjct: 448 RHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLS 507

Query: 492 GKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCI 551
           G+A++ +APLTI   R + I+FSKPF   G++I++KK +  +  + SF+ P    +W+ +
Sbjct: 508 GQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLV 566

Query: 552 VFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGC 611
             +   V+V+L+L+ RFSP+       E+ +E       +   + +++WFS G  +  G 
Sbjct: 567 GLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEE-------DALTLSSAMWFSWGVLLNSGI 619

Query: 612 -DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EI 667
            + +PRS S RI+G VW  F +II++SYTANLAAFL ++R    I    D   +    + 
Sbjct: 620 GEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKF 679

Query: 668 AYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLE 727
            Y T+   S   +FRR       ++ T  R  E   +  + AE +  VR +K   AF+ +
Sbjct: 680 IYATVKQSSVDIYFRRQ-----VELSTMYRHMEKHNY-ESAAEAIQAVRDNK-LHAFIWD 732

Query: 728 STMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGLLDKLKNK 787
           S + E+ E  + CD +  G      G+G+   K S     V+L++LK +E G ++ L +K
Sbjct: 733 SAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDL-DK 790

Query: 788 WWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRM 847
            W    EC S      +  + L+  N+AGVF ++ GG+   + +  IE  YK   +A+R 
Sbjct: 791 TWVRYQECDS----RSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRK 846

Query: 848 KV 849
           ++
Sbjct: 847 QM 848


>gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens]
          Length = 901

 Score =  218 bits (556), Expect = 2e-56
 Identities = 171/602 (28%), Positives = 290/602 (48%), Gaps = 75/602 (12%)

Query: 295 KYTSALTYDGVLVMAETFRSL-RRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVR 353
           K  SA   D V V+A+    L  ++ I    RG    C+ N    W  G   +R L   +
Sbjct: 275 KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329

Query: 354 I-QGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAI 412
              G+TG V+F+  G R      +  L++    +VG +N    +   + +   G +T   
Sbjct: 330 YADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKP 389

Query: 413 E----NRTVVVTTIMESPYVMYKKNHEMFEGNDKYE------------------------ 444
                +  + + TI + P+V  K    + +G  K E                        
Sbjct: 390 RGYQMSTRLKIVTIHQEPFVYVKPT--LSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSP 447

Query: 445 ---------GYCVDLASEIAKHIGIKYKIAIVPDGKYGARD----ADTKIWNGMVGELVY 491
                    G+C+DL  ++A+ +   Y++ +V DGK+G ++    ++ K WNGM+GEL+ 
Sbjct: 448 RHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLS 507

Query: 492 GKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCI 551
           G+A++ +APLTI   R + I+FSKPF   G++I++KK +  +  + SF+ P    +W+ +
Sbjct: 508 GQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLV 566

Query: 552 VFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGC 611
             +   V+V+L+L+ RFSP+       E+ +E       +   + +++WFS G  +  G 
Sbjct: 567 GLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEE-------DALTLSSAMWFSWGVLLNSGI 619

Query: 612 -DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EI 667
            + +PRS S RI+G VW  F +II++SYTANLAAFL ++R    I    D   +    + 
Sbjct: 620 GEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKF 679

Query: 668 AYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLE 727
            Y T+   S   +FRR       ++ T  R  E   +  + AE +  VR +K   AF+ +
Sbjct: 680 IYATVKQSSVDIYFRRQ-----VELSTMYRHMEKHNY-ESAAEAIQAVRDNK-LHAFIWD 732

Query: 728 STMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGLLDKLKNK 787
           S + E+ E  + CD +  G      G+G+   K S     V+L++LK +E G ++ L +K
Sbjct: 733 SAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDL-DK 790

Query: 788 WWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRM 847
            W    EC S      +  + L+  N+AGVF ++ GG+   + +  IE  YK   +A+R 
Sbjct: 791 TWVRYQECDS----RSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRK 846

Query: 848 KV 849
           ++
Sbjct: 847 QM 848


>gi|55770854 N-methyl-D-aspartate receptor subunit 2C precursor
           [Homo sapiens]
          Length = 1233

 Score =  194 bits (494), Expect = 2e-49
 Identities = 215/883 (24%), Positives = 364/883 (41%), Gaps = 126/883 (14%)

Query: 11  LFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDN 70
           LF  + GL  G     + +  +F  ++      FR  +    T  +  + P  + P    
Sbjct: 14  LFGAWAGLGPGQGEQGMTVAVVF-SSSGPPQAQFRARL----TPQSFLDLPLEIQPLTVG 68

Query: 71  IETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHT------LTSFCSALHISLITPS--- 121
           + T N  ++    C     G   + G+  + +V T      L    S  H+ +++ S   
Sbjct: 69  VNTTNPSSLLTQICGLL--GAAHVHGIVFEDNVDTEAVAQILDFISSQTHVPILSISGGS 126

Query: 122 ----FPTEGESQFVLQLRPSLRG---ALLSLLDHYEWNCFVFLYDTDRGYSI----LQAI 170
                P E  S F LQL  SL      L  +L+ Y+W+ F  +     G+++    ++A+
Sbjct: 127 AVVLTPKEPGSAF-LQLGVSLEQQLQVLFKVLEEYDWSAFAVITSLHPGHALFLEGVRAV 185

Query: 171 MEKAGQNGWHVSAICVENFNDVSYRQLLEELDRRQEKK-FVIDCEIERLQNILEQIVSVG 229
            + A    W +  +          R   + L R+ +   FV  C  E  + +  +    G
Sbjct: 186 AD-ASHVSWRLLDVVTLELGPGGPRARTQRLLRQLDAPVFVAYCSREEAEVLFAEAAQAG 244

Query: 230 KHVKGYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPG 289
               G+ +++ NL                 T      F   ++  + + W+ L  R+   
Sbjct: 245 LVGPGHVWLVPNLALGS-------------TDAPPATFPVGLISVVTESWR-LSLRQK-- 288

Query: 290 SETPPKYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTL 349
                        DGV ++A    S  RQ   +     AGDC  +P           R L
Sbjct: 289 -----------VRDGVAILALGAHSYWRQHGTLP--APAGDCRVHPGPVSPAREAFYRHL 335

Query: 350 KQVRIQGLTGNVQFDHYGRRVNYTMDVFELKSTGP-RKVGYWNDMDKLVLIQDVPTLGND 408
             V  +G   +  F   G  V  TM V  L        VG W   +  VL    P     
Sbjct: 336 LNVTWEGR--DFSFSPGGYLVQPTMVVIALNRHRLWEMVGRW---EHGVLYMKYPVWPRY 390

Query: 409 TAA----IENRTVVVTTIMESPYVMYKK-------------------NHEMFEGNDK--- 442
           +A+    +++R + V T+ E P+V+ +                    NH    G+     
Sbjct: 391 SASLQPVVDSRHLTVATLEERPFVIVESPDPGTGGCVPNTVPCRRQSNHTFSSGDVAPYT 450

Query: 443 ---YEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIA 499
               +G+C+D+  ++A+ +   Y + +V +GK+G R     +WNGM+GE+ Y +A++AI 
Sbjct: 451 KLCCKGFCIDILKKLARVVKFSYDLYLVTNGKHGKRVRG--VWNGMIGEVYYKRADMAIG 508

Query: 500 PLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGV 558
            LTI   R E++DFS PF+  GIS+M+ +         +FL+P +  +W M  V     V
Sbjct: 509 SLTINEERSEIVDFSVPFVETGISVMVAR-SNGTVSPSAFLEPYSPAVWVMMFVMCLTVV 567

Query: 559 SVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDI-SPRS 617
           ++ +F+   FSP  ++       K G        F I  S+W            I +PR 
Sbjct: 568 AITVFMFEYFSPVSYNQNLTRGKKSGGP-----AFTIGKSVWLLWALVFNNSVPIENPRG 622

Query: 618 LSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGT 671
            + +I+  VW FF +I ++SYTANLAAF+  E+ +  +    D   Q          +GT
Sbjct: 623 TTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQRPQDQYPPFRFGT 682

Query: 672 LDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMN 731
           + +GST+   R +    Y  M T+M       F + + E      K     AF+ ++ + 
Sbjct: 683 VPNGSTERNIRSN----YRDMHTHMVK-----FNQRSVEDALTSLKMGKLDAFIYDAAVL 733

Query: 732 EYIEQR-KPCDTMKVGGN--LDSKGYGVATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKW 788
            Y+  + + C  + +G      + GYG+A  K S    A++LA+L+    G   KL+  W
Sbjct: 734 NYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQFLGDGETQKLETVW 793

Query: 789 WYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLV 831
               G C +    ++  +S L + N+AGVFY+L+  +GLA+LV
Sbjct: 794 L--SGICQN--EKNEVMSSKLDIDNMAGVFYMLLVAMGLALLV 832


>gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor
           [Homo sapiens]
          Length = 1484

 Score =  191 bits (485), Expect = 3e-48
 Identities = 197/794 (24%), Positives = 337/794 (42%), Gaps = 117/794 (14%)

Query: 99  DKRSVHTLTSFCSALHISLITPSFPTEG----------ESQFVLQLRPSLR---GALLSL 145
           D+ ++  +  F SA     +TP     G          ES    Q  PS+      +L++
Sbjct: 104 DQEAIAQILDFISA---QTLTPILGIHGGSSMIMADKDESSMFFQFGPSIEQQASVMLNI 160

Query: 146 LDHYEWNCFVFLYDTDRGYSILQAIMEKAGQN---GWHVSAICVENFN-DVSYRQLLEEL 201
           ++ Y+W  F  +     GY      +    +N   GW +  + + + + D    ++  +L
Sbjct: 161 MEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKIQNQL 220

Query: 202 DRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIHGGANVTG 261
            + Q    ++ C  E    I E   SVG    GY +I+ +L   D             T 
Sbjct: 221 KKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGD-------------TD 267

Query: 262 FQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSALTYDGVLVMAETFRSLRRQKID 321
               +F T ++    D W      +Y           A   DG+ ++      +  +   
Sbjct: 268 TVPAEFPTGLISVSYDEW------DYG--------LPARVRDGIAIITTAASDMLSEHSF 313

Query: 322 ISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVNYTMDVFEL-K 380
           I    ++  C         Q   + R L  V  +G   N+ F   G +++  + +  L K
Sbjct: 314 IPEPKSS--CYNTHEKRIYQSNMLNRYLINVTFEGR--NLSFSEDGYQMHPKLVIILLNK 369

Query: 381 STGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIMESPYVMY---------- 430
                +VG W D    +     P +  +T   E+  + + T+ E+P+V+           
Sbjct: 370 ERKWERVGKWKDKSLQMKYYVWPRMCPETEEQEDDHLSIVTLEEAPFVIVESVDPLSGTC 429

Query: 431 ---------------KKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGAR 475
                          K + E        +G+C+D+  +I+K +   Y + +V +GK+G +
Sbjct: 430 MRNTVPCQKRIVTENKTDEEPGYIKKCCKGFCIDILKKISKSVKFTYDLYLVTNGKHGKK 489

Query: 476 DADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 535
              T  WNGM+GE+V  +A +A+  LTI   R EV+DFS PF+  GIS+M+ +       
Sbjct: 490 INGT--WNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSR-SNGTVS 546

Query: 536 VFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKE--GPSDQPPNE 592
             +FL+P + ++W M  V   I  +V +F+   FSP  ++     DG+E  GPS      
Sbjct: 547 PSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYN-RCLADGREPGGPS------ 599

Query: 593 FGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERM 651
           F I  ++W   G        + +P+  + +I+  VW FF +I ++SYTANLAAF+  E  
Sbjct: 600 FTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEY 659

Query: 652 VSPIESAEDLAKQ------TEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFT 705
           V  +    D   Q          +GT+ +GST+   R +    Y +M  YM       F 
Sbjct: 660 VDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNN----YAEMHAYM-----GKFN 710

Query: 706 RTTAEGVARVRKSKGKFAFLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGVATPKGS 762
           +   +      K+    AF+ ++ +  Y+  R + C  + +G      S GYG+A  K S
Sbjct: 711 QRGVDDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDS 770

Query: 763 SLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILV 822
                V+LA+L+L   G +++L+  W    G C +    ++  +S L + N+AGVFY+  
Sbjct: 771 GWKRQVDLAILQLFGDGEMEELEALWL--TGICHN--EKNEVMSSQLDIDNMAGVFYM-- 824

Query: 823 GGLGLAMLVALIEF 836
             LG AM ++LI F
Sbjct: 825 --LGAAMALSLITF 836


>gi|197313638 N-methyl-D-aspartate receptor subunit 2A isoform 2
           precursor [Homo sapiens]
          Length = 1281

 Score =  172 bits (435), Expect = 2e-42
 Identities = 120/410 (29%), Positives = 206/410 (50%), Gaps = 40/410 (9%)

Query: 444 EGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTI 503
           +G+C+D+  ++++ +   Y + +V +GK+G +     +WNGM+GE+VY +A +A+  LTI
Sbjct: 457 KGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV--NNVWNGMIGEVVYQRAVMAVGSLTI 514

Query: 504 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVL 562
              R EV+DFS PF+  GIS+M+ +         +FL+P +  +W M  V   I  ++ +
Sbjct: 515 NEERSEVVDFSVPFVETGISVMVSR-SNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAV 573

Query: 563 FLVSRFSPYEWHTEEPE-DGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSG 620
           F+   FSP  ++    +     GPS      F I  ++W   G        + +P+  + 
Sbjct: 574 FVFEYFSPVGYNRNLAKGKAPHGPS------FTIGKAIWLLWGLVFNNSVPVQNPKGTTS 627

Query: 621 RIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLDS 674
           +I+  VW FF +I ++SYTANLAAF+  E  V  +    D   Q          +GT+ +
Sbjct: 628 KIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPN 687

Query: 675 GSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGV--ARVRKSKGKF-AFLLESTMN 731
           GST+   R +    Y  M  YM        T+   +GV  A V    GK  AF+ ++ + 
Sbjct: 688 GSTERNIRNN----YPYMHQYM--------TKFNQKGVEDALVSLKTGKLDAFIYDAAVL 735

Query: 732 EYIEQR-KPCDTMKVGGN--LDSKGYGVATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKW 788
            Y   R + C  + +G      + GYG+A  KGS     ++LA+L+    G +++L+  W
Sbjct: 736 NYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLW 795

Query: 789 WYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 838
               G C +    ++  +S L + N+AGVFY+L   + L+++  + E  +
Sbjct: 796 L--TGICHN--EKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLF 841


>gi|197313636 N-methyl-D-aspartate receptor subunit 2A isoform 1
           precursor [Homo sapiens]
          Length = 1464

 Score =  172 bits (435), Expect = 2e-42
 Identities = 120/410 (29%), Positives = 206/410 (50%), Gaps = 40/410 (9%)

Query: 444 EGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTI 503
           +G+C+D+  ++++ +   Y + +V +GK+G +     +WNGM+GE+VY +A +A+  LTI
Sbjct: 457 KGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV--NNVWNGMIGEVVYQRAVMAVGSLTI 514

Query: 504 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVL 562
              R EV+DFS PF+  GIS+M+ +         +FL+P +  +W M  V   I  ++ +
Sbjct: 515 NEERSEVVDFSVPFVETGISVMVSR-SNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAV 573

Query: 563 FLVSRFSPYEWHTEEPE-DGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSG 620
           F+   FSP  ++    +     GPS      F I  ++W   G        + +P+  + 
Sbjct: 574 FVFEYFSPVGYNRNLAKGKAPHGPS------FTIGKAIWLLWGLVFNNSVPVQNPKGTTS 627

Query: 621 RIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLDS 674
           +I+  VW FF +I ++SYTANLAAF+  E  V  +    D   Q          +GT+ +
Sbjct: 628 KIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPN 687

Query: 675 GSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGV--ARVRKSKGKF-AFLLESTMN 731
           GST+   R +    Y  M  YM        T+   +GV  A V    GK  AF+ ++ + 
Sbjct: 688 GSTERNIRNN----YPYMHQYM--------TKFNQKGVEDALVSLKTGKLDAFIYDAAVL 735

Query: 732 EYIEQR-KPCDTMKVGGN--LDSKGYGVATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKW 788
            Y   R + C  + +G      + GYG+A  KGS     ++LA+L+    G +++L+  W
Sbjct: 736 NYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLW 795

Query: 789 WYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 838
               G C +    ++  +S L + N+AGVFY+L   + L+++  + E  +
Sbjct: 796 L--TGICHN--EKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLF 841


>gi|4504125 N-methyl-D-aspartate receptor subunit 2A isoform 1
           precursor [Homo sapiens]
          Length = 1464

 Score =  172 bits (435), Expect = 2e-42
 Identities = 120/410 (29%), Positives = 206/410 (50%), Gaps = 40/410 (9%)

Query: 444 EGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTI 503
           +G+C+D+  ++++ +   Y + +V +GK+G +     +WNGM+GE+VY +A +A+  LTI
Sbjct: 457 KGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV--NNVWNGMIGEVVYQRAVMAVGSLTI 514

Query: 504 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVL 562
              R EV+DFS PF+  GIS+M+ +         +FL+P +  +W M  V   I  ++ +
Sbjct: 515 NEERSEVVDFSVPFVETGISVMVSR-SNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAV 573

Query: 563 FLVSRFSPYEWHTEEPE-DGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSG 620
           F+   FSP  ++    +     GPS      F I  ++W   G        + +P+  + 
Sbjct: 574 FVFEYFSPVGYNRNLAKGKAPHGPS------FTIGKAIWLLWGLVFNNSVPVQNPKGTTS 627

Query: 621 RIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLDS 674
           +I+  VW FF +I ++SYTANLAAF+  E  V  +    D   Q          +GT+ +
Sbjct: 628 KIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPN 687

Query: 675 GSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGV--ARVRKSKGKF-AFLLESTMN 731
           GST+   R +    Y  M  YM        T+   +GV  A V    GK  AF+ ++ + 
Sbjct: 688 GSTERNIRNN----YPYMHQYM--------TKFNQKGVEDALVSLKTGKLDAFIYDAAVL 735

Query: 732 EYIEQR-KPCDTMKVGGN--LDSKGYGVATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKW 788
            Y   R + C  + +G      + GYG+A  KGS     ++LA+L+    G +++L+  W
Sbjct: 736 NYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLW 795

Query: 789 WYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 838
               G C +    ++  +S L + N+AGVFY+L   + L+++  + E  +
Sbjct: 796 L--TGICHN--EKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLF 841


>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor
           [Homo sapiens]
          Length = 1336

 Score =  171 bits (433), Expect = 3e-42
 Identities = 120/400 (30%), Positives = 205/400 (51%), Gaps = 34/400 (8%)

Query: 444 EGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTI 503
           +G+C+D+   +A  IG  Y + +V +GK+G +     +WNGM+GE+ Y +A++AI  LTI
Sbjct: 485 KGFCIDILKRLAHTIGFSYDLYLVTNGKHGKKIDG--VWNGMIGEVFYQRADMAIGSLTI 542

Query: 504 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVL 562
              R E++DFS PF+  GIS+M+ +         +FL+P +  +W M  V     V+V +
Sbjct: 543 NEERSEIVDFSVPFVETGISVMVAR-SNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTV 601

Query: 563 FLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGR 621
           F+    SP  ++       + G S      F I  S+W            + +PR  + +
Sbjct: 602 FIFEYLSPVGYNRSLATGKRPGGS-----TFTIGKSIWLLWALVFNNSVPVENPRGTTSK 656

Query: 622 IVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLDSG 675
           I+  VW FF +I ++SYTANLAAF+  E  V  +    D   Q        + +GT+ +G
Sbjct: 657 IMVLVWAFFAVIFLASYTANLAAFMIQEEYVDTVSGLSDRKFQRPQEQYPPLKFGTVPNG 716

Query: 676 STKEFFRRSKIAVYEKMWTYM-RSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYI 734
           ST++  R +    Y  M +YM R  +P V      E + +++  K   AF+ ++ +  Y+
Sbjct: 717 STEKNIRSN----YPDMHSYMVRYNQPRV-----EEALTQLKAGK-LDAFIYDAAVLNYM 766

Query: 735 EQR-KPCDTMKVGGN--LDSKGYGVATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYD 791
            ++ + C  + +G      + GYG+A  KGS     ++LA+L+      ++ L+  W   
Sbjct: 767 ARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEMLERLWL-- 824

Query: 792 KGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLV 831
            G C +     +  +S L + N+AGVFY+L+  +GL++LV
Sbjct: 825 SGICHN--DKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLV 862


>gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
           [Homo sapiens]
          Length = 1043

 Score =  154 bits (388), Expect = 5e-37
 Identities = 120/437 (27%), Positives = 213/437 (48%), Gaps = 41/437 (9%)

Query: 445 GYCVDLASEIAKHIGIKYKIAIVPDGKYGA-RDADTKIWNGMVGELVYGKAEIAIAPLTI 503
           GYC+DL   +A+     +++ +V DGKYGA RD     W G+VG+L+ G+A +A+   +I
Sbjct: 478 GYCIDLLERLAEDTPFDFELYLVGDGKYGALRDGR---WTGLVGDLLAGRAHMAVTSFSI 534

Query: 504 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLF 563
              R +V+DF+ PF S  + IM++    + P + +F+ PL +  W       +GV   L 
Sbjct: 535 NSARSQVVDFTSPFFSTSLGIMVRARDTASP-IGAFMWPLHWSTW-------LGVFAALH 586

Query: 564 LVSRF-SPYEWHTEEPEDGKEGPSDQPPNEFGIFN-----SLWFSLGAFMQQGCDISPRS 617
           L + F + YEW +        G + +  N   +F+     +L +++  F +     +P+ 
Sbjct: 587 LTALFLTVYEWRS------PYGLTPRGRNRSTVFSYSSALNLCYAI-LFRRTVSSKTPKC 639

Query: 618 LSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLA---KQTEIAYGTLDS 674
            +GR++  +W  F L+++SSYTANLAA +  ++    +    D           +GT+  
Sbjct: 640 PTGRLLMNLWAIFCLLVLSSYTANLAAVMVGDKTFEELSGIHDPKLHHPAQGFRFGTVWE 699

Query: 675 GSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKF-AFLLESTMNEY 733
            S + + ++S    +  M  +MR         TT  GVA +     K  AF+++ ++ +Y
Sbjct: 700 SSAEAYIKKS----FPDMHAHMRRHS----APTTPRGVAMLTSDPPKLNAFIMDKSLLDY 751

Query: 734 -IEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDK 792
            +     C  + VG     +GYG+  P+ S L + ++  + +    G +D L +K WY  
Sbjct: 752 EVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDK-WYKM 810

Query: 793 GECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKS 852
             CG     +  +T  +S+ + AG+F +L  GLG A+L +L E  +  R    R++    
Sbjct: 811 VPCGK-RVFAVTETLQMSIYHFAGLFVLLCLGLGSALLSSLGEHAF-FRLALPRIRKGSR 868

Query: 853 AQTFNPTSSQNTQNLAT 869
            Q +  TS +  + L T
Sbjct: 869 LQYWLHTSQKIHRALNT 885


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,255,741
Number of Sequences: 37866
Number of extensions: 1346751
Number of successful extensions: 3235
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3047
Number of HSP's gapped (non-prelim): 52
length of query: 884
length of database: 18,247,518
effective HSP length: 111
effective length of query: 773
effective length of database: 14,044,392
effective search space: 10856315016
effective search space used: 10856315016
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.