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Search of human proteins with 164419734
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1
precursor [Homo sapiens]
(902 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1 p... 1814 0.0
gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2 p... 1689 0.0
gi|163659856 glutamate receptor, ionotrophic, AMPA 3 isoform 1 p... 1336 0.0
gi|163659858 glutamate receptor, ionotrophic, AMPA 3 isoform 2 p... 1319 0.0
gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1 pre... 1308 0.0
gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2 pr... 1291 0.0
gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3 [H... 1271 0.0
gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2 [H... 1235 0.0
gi|167001419 glutamate receptor, ionotropic, AMPA 1 isoform 1 [H... 1226 0.0
gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3 p... 857 0.0
gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3 p... 857 0.0
gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1 ... 593 e-169
gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor ... 590 e-168
gi|28416444 glutamate receptor, ionotropic, kainate 1 isoform 2 ... 588 e-168
gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2 ... 586 e-167
gi|4504117 glutamate receptor, ionotropic, kainate 1 isoform 1 p... 579 e-165
gi|29029597 glutamate receptor KA2 precursor [Homo sapiens] 500 e-141
gi|29029595 glutamate receptor KA1 precursor [Homo sapiens] 494 e-139
gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens] 333 3e-91
gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [H... 332 1e-90
gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens] 220 4e-57
gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens] 218 2e-56
gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens] 218 3e-56
gi|55770854 N-methyl-D-aspartate receptor subunit 2C precursor [... 194 4e-49
gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor ... 191 2e-48
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ... 174 3e-43
gi|197313638 N-methyl-D-aspartate receptor subunit 2A isoform 2 ... 172 1e-42
gi|197313636 N-methyl-D-aspartate receptor subunit 2A isoform 1 ... 172 1e-42
gi|4504125 N-methyl-D-aspartate receptor subunit 2A isoform 1 pr... 172 1e-42
gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate... 155 1e-37
>gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1
precursor [Homo sapiens]
Length = 902
Score = 1814 bits (4698), Expect = 0.0
Identities = 902/902 (100%), Positives = 902/902 (100%)
Query: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
Sbjct: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
Query: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
Sbjct: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
Query: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
Sbjct: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
Query: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL
Sbjct: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
Query: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
Sbjct: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
Query: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT
Sbjct: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
Query: 421 TIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTK 480
TIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTK
Sbjct: 421 TIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTK 480
Query: 481 IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 540
IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL
Sbjct: 481 IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 540
Query: 541 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLW 600
DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLW
Sbjct: 541 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLW 600
Query: 601 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 660
FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED
Sbjct: 601 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 660
Query: 661 LAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKG 720
LAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKG
Sbjct: 661 LAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKG 720
Query: 721 KFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSEAGV 780
KFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSEAGV
Sbjct: 721 KFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSEAGV 780
Query: 781 LDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKS 840
LDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKS
Sbjct: 781 LDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKS 840
Query: 841 RAEAKRMKLTFSEAIRNKARLSITGSVGENGRVLTPDCPKAVHTGTAIRQSSGLAVIASD 900
RAEAKRMKLTFSEAIRNKARLSITGSVGENGRVLTPDCPKAVHTGTAIRQSSGLAVIASD
Sbjct: 841 RAEAKRMKLTFSEAIRNKARLSITGSVGENGRVLTPDCPKAVHTGTAIRQSSGLAVIASD 900
Query: 901 LP 902
LP
Sbjct: 901 LP 902
>gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2
precursor [Homo sapiens]
Length = 884
Score = 1689 bits (4375), Expect = 0.0
Identities = 839/852 (98%), Positives = 842/852 (98%)
Query: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
Sbjct: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
Query: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
Sbjct: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
Query: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
Sbjct: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
Query: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL
Sbjct: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
Query: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
Sbjct: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
Query: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT
Sbjct: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
Query: 421 TIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTK 480
TIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTK
Sbjct: 421 TIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTK 480
Query: 481 IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 540
IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL
Sbjct: 481 IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 540
Query: 541 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLW 600
DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLW
Sbjct: 541 DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLW 600
Query: 601 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 660
FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED
Sbjct: 601 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 660
Query: 661 LAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKG 720
LAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKG
Sbjct: 661 LAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKG 720
Query: 721 KFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSEAGV 780
KFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLG VNLAVLKL+E G+
Sbjct: 721 KFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGL 780
Query: 781 LDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKS 840
LDKLKNKWWYDKGECG SKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKS
Sbjct: 781 LDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKS 840
Query: 841 RAEAKRMKLTFS 852
RAEAKRMK+ S
Sbjct: 841 RAEAKRMKVAKS 852
>gi|163659856 glutamate receptor, ionotrophic, AMPA 3 isoform 1
precursor [Homo sapiens]
Length = 894
Score = 1336 bits (3457), Expect = 0.0
Identities = 646/853 (75%), Positives = 752/853 (88%), Gaps = 9/853 (1%)
Query: 4 ISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFN 63
+ R + L G G + G FP+++ IGGLF+RNT QE++AFR A+ L+NT+ N +E PF+
Sbjct: 11 VLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFH 70
Query: 64 LVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFP 123
L HVD+++++NSF+VTNAFCSQ+SRGV+AIFG YD+ S++TLTSFC ALH S +TPSFP
Sbjct: 71 LNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFP 130
Query: 124 TEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSA 183
T+ + QFV+Q+RP+L+GA+LSLL HY+W FV+LYDT+RG+SILQAIME A QN W V+A
Sbjct: 131 TDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTA 190
Query: 184 ICVENFNDVS-YRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
V N DV +R+++EE+DRRQEK+++IDCE+ER+ ILEQ+V +GKH +GYHY++ANL
Sbjct: 191 RSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANL 250
Query: 243 GFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-KYTSALT 301
GF DI LER +HGGAN+TGFQ+V+ PMV + + RW +LD+RE+P ++ P KYTSALT
Sbjct: 251 GFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALT 310
Query: 302 YDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNV 361
+D +LV+AE FR LRRQ++D+SRRG+AGDCLANPA PW QGID+ER LK V++QG+TGN+
Sbjct: 311 HDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNI 370
Query: 362 QFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTT 421
QFD YGRR NYT+DV+E+K +G RK GYWN+ ++ V D + ND+A+ ENRT+VVTT
Sbjct: 371 QFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSD-QQISNDSASSENRTIVVTT 429
Query: 422 IMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKI 481
I+ESPYVMYKKNHE EGN++YEGYCVDLA EIAKH+ IKYK++IV DGKYGARD +TKI
Sbjct: 430 ILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKI 489
Query: 482 WNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 541
WNGMVGELVYG+A+IA+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD
Sbjct: 490 WNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 549
Query: 542 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH----TEEPEDGKEGPSDQPPNEFGIFN 597
PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH EEP D + P PPNEFGIFN
Sbjct: 550 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPD--PPNEFGIFN 607
Query: 598 SLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 657
SLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES
Sbjct: 608 SLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 667
Query: 658 AEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRK 717
AEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMW+YM+SAEPSVFT+TTA+GVARVRK
Sbjct: 668 AEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRK 727
Query: 718 SKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSE 777
SKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGS+LGTPVNLAVLKLSE
Sbjct: 728 SKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSE 787
Query: 778 AGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFC 837
G+LDKLKNKWWYDKGECG KDSGSKDKTSALSLSNVAGVFYILVGGLGLAM+VALIEFC
Sbjct: 788 QGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFC 847
Query: 838 YKSRAEAKRMKLT 850
YKSRAE+KRMKLT
Sbjct: 848 YKSRAESKRMKLT 860
>gi|163659858 glutamate receptor, ionotrophic, AMPA 3 isoform 2
precursor [Homo sapiens]
Length = 894
Score = 1319 bits (3414), Expect = 0.0
Identities = 639/853 (74%), Positives = 746/853 (87%), Gaps = 9/853 (1%)
Query: 4 ISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFN 63
+ R + L G G + G FP+++ IGGLF+RNT QE++AFR A+ L+NT+ N +E PF+
Sbjct: 11 VLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFH 70
Query: 64 LVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFP 123
L HVD+++++NSF+VTNAFCSQ+SRGV+AIFG YD+ S++TLTSFC ALH S +TPSFP
Sbjct: 71 LNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFP 130
Query: 124 TEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSA 183
T+ + QFV+Q+RP+L+GA+LSLL HY+W FV+LYDT+RG+SILQAIME A QN W V+A
Sbjct: 131 TDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTA 190
Query: 184 ICVENFNDVS-YRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
V N DV +R+++EE+DRRQEK+++IDCE+ER+ ILEQ+V +GKH +GYHY++ANL
Sbjct: 191 RSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANL 250
Query: 243 GFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-KYTSALT 301
GF DI LER +HGGAN+TGFQ+V+ PMV + + RW +LD+RE+P ++ P KYTSALT
Sbjct: 251 GFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALT 310
Query: 302 YDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNV 361
+D +LV+AE FR LRRQ++D+SRRG+AGDCLANPA PW QGID+ER LK V++QG+TGN+
Sbjct: 311 HDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNI 370
Query: 362 QFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTT 421
QFD YGRR NYT+DV+E+K +G RK GYWN+ ++ V D + ND+A+ ENRT+VVTT
Sbjct: 371 QFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSD-QQISNDSASSENRTIVVTT 429
Query: 422 IMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKI 481
I+ESPYVMYKKNHE EGN++YEGYCVDLA EIAKH+ IKYK++IV DGKYGARD +TKI
Sbjct: 430 ILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKI 489
Query: 482 WNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 541
WNGMVGELVYG+A+IA+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD
Sbjct: 490 WNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 549
Query: 542 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH----TEEPEDGKEGPSDQPPNEFGIFN 597
PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH EEP D + P PPNEFGIFN
Sbjct: 550 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPD--PPNEFGIFN 607
Query: 598 SLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 657
SLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES
Sbjct: 608 SLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 667
Query: 658 AEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRK 717
AEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMW+YM+SAEPSVFT+TTA+GVARVRK
Sbjct: 668 AEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRK 727
Query: 718 SKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSE 777
SKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGS+LG VNLAVLKL+E
Sbjct: 728 SKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGNAVNLAVLKLNE 787
Query: 778 AGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFC 837
G+LDKLKNKWWYDKGECG SKDKTSALSLSNVAGVFYILVGGLGLAM+VALIEFC
Sbjct: 788 QGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFC 847
Query: 838 YKSRAEAKRMKLT 850
YKSRAE+KRMKLT
Sbjct: 848 YKSRAESKRMKLT 860
>gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1
precursor [Homo sapiens]
Length = 883
Score = 1308 bits (3386), Expect = 0.0
Identities = 633/854 (74%), Positives = 740/854 (86%), Gaps = 11/854 (1%)
Query: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
M+ I VLL WGL G +S+QIGGLF R DQEY+AFR+ + +TS
Sbjct: 1 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- 55
Query: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC LH+S ITP
Sbjct: 56 -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP 114
Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
SFPT+G FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A + W
Sbjct: 115 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174
Query: 181 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 236
V+AI V N N D YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVKGYH
Sbjct: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234
Query: 237 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 295
YIIANLGF D L + GGANV+GFQ+VD++ +V K ++RW L+++EYPG+ T K
Sbjct: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK 294
Query: 296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 355
YTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV+++
Sbjct: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354
Query: 356 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR 415
GL+GN++FD G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+ GNDT+ +EN+
Sbjct: 355 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK 414
Query: 416 TVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGAR 475
TVVVTTI+ESPYVM KKNHEM EGN++YEGYCVDLA+EIAKH G KYK+ IV DGKYGAR
Sbjct: 415 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGAR 474
Query: 476 DADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 535
DADTKIWNGMVGELVYGKA+IAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG
Sbjct: 475 DADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 534
Query: 536 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGI 595
VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEE EDG+E S + NEFGI
Sbjct: 535 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 594
Query: 596 FNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI 655
FNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI
Sbjct: 595 FNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI 654
Query: 656 ESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARV 715
ESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMWTYMRSAEPSVF RTTAEGVARV
Sbjct: 655 ESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARV 714
Query: 716 RKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKL 775
RKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSSL TPVNLAVLKL
Sbjct: 715 RKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKL 774
Query: 776 SEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIE 835
SE GVLDKLKNKWWYDKGECG KDSGSK+KTSALSLSNVAGVFYILVGGLGLAMLVALIE
Sbjct: 775 SEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIE 834
Query: 836 FCYKSRAEAKRMKL 849
FCYKSRAEAKRMK+
Sbjct: 835 FCYKSRAEAKRMKV 848
>gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2
precursor [Homo sapiens]
Length = 883
Score = 1291 bits (3342), Expect = 0.0
Identities = 625/854 (73%), Positives = 734/854 (85%), Gaps = 11/854 (1%)
Query: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
M+ I VLL WGL G +S+QIGGLF R DQEY+AFR+ + +TS
Sbjct: 1 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- 55
Query: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC LH+S ITP
Sbjct: 56 -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP 114
Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
SFPT+G FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A + W
Sbjct: 115 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174
Query: 181 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 236
V+AI V N N D YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVKGYH
Sbjct: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234
Query: 237 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 295
YIIANLGF D L + GGANV+GFQ+VD++ +V K ++RW L+++EYPG+ T K
Sbjct: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK 294
Query: 296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 355
YTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV+++
Sbjct: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354
Query: 356 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR 415
GL+GN++FD G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+ GNDT+ +EN+
Sbjct: 355 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK 414
Query: 416 TVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGAR 475
TVVVTTI+ESPYVM KKNHEM EGN++YEGYCVDLA+EIAKH G KYK+ IV DGKYGAR
Sbjct: 415 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGAR 474
Query: 476 DADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 535
DADTKIWNGMVGELVYGKA+IAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG
Sbjct: 475 DADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 534
Query: 536 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGI 595
VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEE EDG+E S + NEFGI
Sbjct: 535 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGI 594
Query: 596 FNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI 655
FNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI
Sbjct: 595 FNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPI 654
Query: 656 ESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARV 715
ESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMWTYMRSAEPSVF RTTAEGVARV
Sbjct: 655 ESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARV 714
Query: 716 RKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKL 775
RKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSSL VNLAVLKL
Sbjct: 715 RKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKL 774
Query: 776 SEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIE 835
+E G+LDKLKNKWWYDKGECG SK+KTSALSLSNVAGVFYILVGGLGLAMLVALIE
Sbjct: 775 NEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIE 834
Query: 836 FCYKSRAEAKRMKL 849
FCYKSRAEAKRMK+
Sbjct: 835 FCYKSRAEAKRMKV 848
>gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3 [Homo
sapiens]
Length = 836
Score = 1271 bits (3289), Expect = 0.0
Identities = 608/797 (76%), Positives = 709/797 (88%), Gaps = 5/797 (0%)
Query: 58 SEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISL 117
S + F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC LH+S
Sbjct: 5 STSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSF 64
Query: 118 ITPSFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQN 177
ITPSFPT+G FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A +
Sbjct: 65 ITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEK 124
Query: 178 GWHVSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVK 233
W V+AI V N N D YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVK
Sbjct: 125 KWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVK 184
Query: 234 GYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP 293
GYHYIIANLGF D L + GGANV+GFQ+VD++ +V K ++RW L+++EYPG+ T
Sbjct: 185 GYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTT 244
Query: 294 P-KYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQV 352
KYTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV
Sbjct: 245 TIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQV 304
Query: 353 RIQGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAI 412
+++GL+GN++FD G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+ GNDT+ +
Sbjct: 305 QVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGL 364
Query: 413 ENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKY 472
EN+TVVVTTI+ESPYVM KKNHEM EGN++YEGYCVDLA+EIAKH G KYK+ IV DGKY
Sbjct: 365 ENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKY 424
Query: 473 GARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 532
GARDADTKIWNGMVGELVYGKA+IAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS
Sbjct: 425 GARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 484
Query: 533 KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNE 592
KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEE EDG+E S + NE
Sbjct: 485 KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNE 544
Query: 593 FGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV 652
FGIFNSLWFSLGAFM+QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV
Sbjct: 545 FGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV 604
Query: 653 SPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGV 712
SPIESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMWTYMRSAEPSVF RTTAEGV
Sbjct: 605 SPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGV 664
Query: 713 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAV 772
ARVRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSSL TPVNLAV
Sbjct: 665 ARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAV 724
Query: 773 LKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVA 832
LKLSE GVLDKLKNKWWYDKGECG KDSGSK+KTSALSLSNVAGVFYILVGGLGLAMLVA
Sbjct: 725 LKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVA 784
Query: 833 LIEFCYKSRAEAKRMKL 849
LIEFCYKSRAEAKRMK+
Sbjct: 785 LIEFCYKSRAEAKRMKV 801
>gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2 [Homo
sapiens]
Length = 906
Score = 1235 bits (3196), Expect = 0.0
Identities = 610/904 (67%), Positives = 729/904 (80%), Gaps = 22/904 (2%)
Query: 13 SGFWGLAMGA-FPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNI 71
+GF G +GA FP+++QIGGLF QE+ AFR A+ + P L+P +D +
Sbjct: 10 TGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFAL-------SQLTEPPKLLPQIDIV 62
Query: 72 ETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFV 131
++SF +T FCSQ+S+GV+AIFG Y++R+V+ LTSFC ALH+ ITPSFP + +QFV
Sbjct: 63 NISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFV 122
Query: 132 LQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFND 191
LQLRP L+ AL+S++DHY+W FV++YD DRG S+LQ +++ A + W V+A+ + +
Sbjct: 123 LQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTE 182
Query: 192 VSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLER 251
YR L ++L++++E+ V+DCE ERL IL QI+ + K+ GYHYI+ANLGF DI L +
Sbjct: 183 EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNK 242
Query: 252 FIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP-PKYTSALTYDGVLVMAE 310
F GANVTGFQLV++ + K+M +WK D R++ + PKYTSALTYDGV VMAE
Sbjct: 243 FKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAE 302
Query: 311 TFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRV 370
F+SLRRQ+IDISRRGNAGDCLANPA PWGQGID++R L+QVR +GLTGNVQF+ GRR
Sbjct: 303 AFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRT 362
Query: 371 NYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIMESPYVMY 430
NYT+ V E+K G RK+GYWN+ DK V G D ++++NRT +VTTI+E PYVM
Sbjct: 363 NYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVML 422
Query: 431 KKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELV 490
KKN FEGND+YEGYCV+LA+EIAKH+G Y++ IV DGKYGARD DTK WNGMVGELV
Sbjct: 423 KKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELV 482
Query: 491 YGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC 550
YG+A++A+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC
Sbjct: 483 YGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC 542
Query: 551 IVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQG 610
IVFAYIGVSVVLFLVSRFSPYEWH+EE E+G++ + NEFGIFNSLWFSLGAFMQQG
Sbjct: 543 IVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQG 602
Query: 611 CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG 670
CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG
Sbjct: 603 CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG 662
Query: 671 TLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTM 730
TL++GSTKEFFRRSKIAV+EKMWTYM+SAEPSVF RTT EG+ RVRKSKGK+A+LLESTM
Sbjct: 663 TLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTM 722
Query: 731 NEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSEAGVLDKLKNKWWY 790
NEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+L PVNLAVLKLSE GVLDKLK+KWWY
Sbjct: 723 NEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWY 782
Query: 791 DKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMK-- 848
DKGECG KDSGSKDKTSALSLSNVAGVFYIL+GGLGLAMLVALIEFCYKSR+E+KRMK
Sbjct: 783 DKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGF 842
Query: 849 -----LTFSEAI------RNKARLSITGSVGENGRVLTPDCPKAVHTGTAIRQSSGLAVI 897
+ +EAI RN + +G GENGRV++ D PK++ + + SSG+ +
Sbjct: 843 CLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMPLG 902
Query: 898 ASDL 901
A+ L
Sbjct: 903 ATGL 906
>gi|167001419 glutamate receptor, ionotropic, AMPA 1 isoform 1 [Homo
sapiens]
Length = 906
Score = 1226 bits (3172), Expect = 0.0
Identities = 605/904 (66%), Positives = 725/904 (80%), Gaps = 22/904 (2%)
Query: 13 SGFWGLAMGA-FPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNI 71
+GF G +GA FP+++QIGGLF QE+ AFR A+ + P L+P +D +
Sbjct: 10 TGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFAL-------SQLTEPPKLLPQIDIV 62
Query: 72 ETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFV 131
++SF +T FCSQ+S+GV+AIFG Y++R+V+ LTSFC ALH+ ITPSFP + +QFV
Sbjct: 63 NISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFV 122
Query: 132 LQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFND 191
LQLRP L+ AL+S++DHY+W FV++YD DRG S+LQ +++ A + W V+A+ + +
Sbjct: 123 LQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTE 182
Query: 192 VSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLER 251
YR L ++L++++E+ V+DCE ERL IL QI+ + K+ GYHYI+ANLGF DI L +
Sbjct: 183 EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNK 242
Query: 252 FIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP-PKYTSALTYDGVLVMAE 310
F GANVTGFQLV++ + K+M +WK D R++ + PKYTSALTYDGV VMAE
Sbjct: 243 FKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAE 302
Query: 311 TFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRV 370
F+SLRRQ+IDISRRGNAGDCLANPA PWGQGID++R L+QVR +GLTGNVQF+ GRR
Sbjct: 303 AFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRT 362
Query: 371 NYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIMESPYVMY 430
NYT+ V E+K G RK+GYWN+ DK V G D ++++NRT +VTTI+E PYVM
Sbjct: 363 NYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVML 422
Query: 431 KKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELV 490
KKN FEGND+YEGYCV+LA+EIAKH+G Y++ IV DGKYGARD DTK WNGMVGELV
Sbjct: 423 KKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELV 482
Query: 491 YGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC 550
YG+A++A+APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC
Sbjct: 483 YGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC 542
Query: 551 IVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQG 610
IVFAYIGVSVVLFLVSRFSPYEWH+EE E+G++ + NEFGIFNSLWFSLGAFMQQG
Sbjct: 543 IVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQG 602
Query: 611 CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG 670
CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG
Sbjct: 603 CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYG 662
Query: 671 TLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTM 730
TL++GSTKEFFRRSKIAV+EKMWTYM+SAEPSVF RTT EG+ RVRKSKGK+A+LLESTM
Sbjct: 663 TLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTM 722
Query: 731 NEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSEAGVLDKLKNKWWY 790
NEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+L PVNLAVLKL+E G+LDKLKNKWWY
Sbjct: 723 NEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWWY 782
Query: 791 DKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMK-- 848
DKGECG SKDKTSALSLSNVAGVFYIL+GGLGLAMLVALIEFCYKSR+E+KRMK
Sbjct: 783 DKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGF 842
Query: 849 -----LTFSEAI------RNKARLSITGSVGENGRVLTPDCPKAVHTGTAIRQSSGLAVI 897
+ +EAI RN + +G GENGRV++ D PK++ + + SSG+ +
Sbjct: 843 CLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMPLG 902
Query: 898 ASDL 901
A+ L
Sbjct: 903 ATGL 906
>gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3
precursor [Homo sapiens]
Length = 433
Score = 857 bits (2213), Expect = 0.0
Identities = 423/423 (100%), Positives = 423/423 (100%)
Query: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
Sbjct: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
Query: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
Sbjct: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
Query: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
Sbjct: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
Query: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL
Sbjct: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
Query: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
Sbjct: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
Query: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT
Sbjct: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
Query: 421 TIM 423
TIM
Sbjct: 421 TIM 423
>gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3
precursor [Homo sapiens]
Length = 433
Score = 857 bits (2213), Expect = 0.0
Identities = 423/423 (100%), Positives = 423/423 (100%)
Query: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
Sbjct: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
Query: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
Sbjct: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
Query: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
Sbjct: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
Query: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL
Sbjct: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
Query: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
Sbjct: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
Query: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT
Sbjct: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
Query: 421 TIM 423
TIM
Sbjct: 421 TIM 423
>gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1
precursor [Homo sapiens]
Length = 908
Score = 593 bits (1529), Expect = e-169
Identities = 345/883 (39%), Positives = 507/883 (57%), Gaps = 47/883 (5%)
Query: 3 IISRQIVLLFSGFW-GLAMGAFPSSVQIGGLF----IRNTDQEYTAFRLAIFLHNTS--- 54
+ R + LL W G + G ++ GG+F E AFR A+ N +
Sbjct: 12 VFRRTVKLLLCLLWIGYSQGT-THVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTL 70
Query: 55 -PNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSAL 113
PN + L I +SF + C Q S GV AIFG S + + S C+AL
Sbjct: 71 LPNTT-----LTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNAL 125
Query: 114 ---HISLITPSFPTEGESQFVLQLRP---SLRGALLSLLDHYEWNCFVFLYDTDRGYSIL 167
HI ++ + F + L P SL A+L L+ ++W +YD G L
Sbjct: 126 GVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRL 185
Query: 168 QAIMEKAGQNGWHVSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVS 227
Q +++ + + I + + LL+E+ R +E + DC E IL+Q ++
Sbjct: 186 QELIKAPSRYNLRLK-IRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALA 244
Query: 228 VGKHVKGYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRW--KKLDQR 285
+G + YHYI L + +E + + G N+TGF++++ V ++++W ++L
Sbjct: 245 MGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAP 304
Query: 286 EYPGSETPPKYTS---ALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQG 342
P S + + AL YD V V++ + + + + N PW G
Sbjct: 305 PKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQ--------CNRHKPWRFG 356
Query: 343 IDMERTLKQVRIQGLTGNVQFDHY-GRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQD 401
+K+ +GLTG + F+ G R ++ +DV LK G K+G W+ L + +
Sbjct: 357 TRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTES 416
Query: 402 VPTL-GNDTAAIENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGI 460
N T ++ NR+++VTTI+E PYV++KK+ + GND++EGYC+DL E++ +G
Sbjct: 417 QKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGF 476
Query: 461 KYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSL 520
Y+I +V DGKYGA+D WNGMV EL+ KA++A+APL IT VRE+VIDFSKPFM+L
Sbjct: 477 TYEIRLVEDGKYGAQDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTL 536
Query: 521 GISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPED 580
GISI+ +KP + PGVFSFL+PL+ +IWM I+ AY+GVS VLF+++RFSPYEW+ P
Sbjct: 537 GISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHP-- 594
Query: 581 GKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTA 640
SD N F + NS WF +GA MQQG ++ P++LS RIVGG+WWFFTLIIISSYTA
Sbjct: 595 -CNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTA 653
Query: 641 NLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAE 700
NLAAFLTVERM SPI+SA+DLAKQT+I YG ++ G+T FF++SKI+ Y+KMW +M S
Sbjct: 654 NLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRR 713
Query: 701 PSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPK 760
SV ++ EG+ RV S +AFL+EST E++ QR C+ ++GG +DSKGYGV TP
Sbjct: 714 QSVLVKSNEEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPM 770
Query: 761 GSSLGTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYI 820
GS + +A+L+L E G L +K KWW G C ++S + SAL + N+ G+F +
Sbjct: 771 GSPYRDKITIAILQLQEEGKLHMMKEKWWRGNG-CPEEES---KEASALGVQNIGGIFIV 826
Query: 821 LVGGLGLAMLVALIEFCYKSRAEAKRMKLTFSEAIRNKARLSI 863
L GL L++ VA+ EF YKS+ A+ K +F A+ + R+S+
Sbjct: 827 LAAGLVLSVFVAVGEFLYKSKKNAQLEKRSFCSAMVEELRMSL 869
>gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor
[Homo sapiens]
Length = 919
Score = 590 bits (1522), Expect = e-168
Identities = 337/879 (38%), Positives = 510/879 (58%), Gaps = 50/879 (5%)
Query: 10 LLFSGFWGLAMGAFPSSVQIGGLF---------IRNTDQEYTAFRLAIFLHNTS--PNAS 58
LL FW P ++IGG+F + N ++ F I N + PN +
Sbjct: 19 LLVCAFWIPDSRGMPHVIRIGGIFEYADGPNAQVMNAEEHAFRFSANIINRNRTLLPNTT 78
Query: 59 EAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSAL---HI 115
L + I +SF T C Q + GV AIFG + + S C+AL HI
Sbjct: 79 -----LTYDIQRIHFHDSFEATKKACDQLALGVVAIFGPSQGSCTNAVQSICNALEVPHI 133
Query: 116 SLITPSFPTEGESQFVLQLRP---SLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIME 172
L P + + F + L P SL A+L L+ + +W +YD G LQ ++
Sbjct: 134 QLRWKHHPLDNKDTFYVNLYPDYASLSHAILDLVQYLKWRSATVVYDDSTGLIRLQELIM 193
Query: 173 KAGQNGWHVSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHV 232
+ + + +D S R LL+E+ R +E + + DC IL+Q +++G
Sbjct: 194 APSRYNIRLKIRQLPIDSDDS-RPLLKEMKRGREFRIIFDCSHTMAAQILKQAMAMGMMT 252
Query: 233 KGYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSET 292
+ YH+I L + LE + + G N+TGF++++ + P V ++++W + P SE+
Sbjct: 253 EYYHFIFTTLDLYALDLEPYRYSGVNLTGFRILNVDNPHVSAIVEKWSMERLQAAPRSES 312
Query: 293 P-----PKYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMER 347
+AL YD V +++ ++ + + N+ C + A W G
Sbjct: 313 GLLDGVMMTDAALLYDAVHIVSVCYQRAPQMTV------NSLQCHRHKA--WRFGGRFMN 364
Query: 348 TLKQVRIQGLTGNVQFDHY-GRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLG 406
+K+ + +GLTG + F+ G R ++ +D+ LK G KVG W+ D L + + G
Sbjct: 365 FIKEAQWEGLTGRIVFNKTSGLRTDFDLDIISLKEDGLEKVGVWSPADGLNITEVAKGRG 424
Query: 407 -NDTAAIENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIA 465
N T ++ NR+++VTT++E P+VM++K+ GND++EGYC+DL E+A +G Y+I
Sbjct: 425 PNVTDSLTNRSLIVTTVLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIR 484
Query: 466 IVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIM 525
+V DGKYGA+D D WNGMV EL+ KA++A+APLTIT VRE+ IDFSKPFM+LG+SI+
Sbjct: 485 LVEDGKYGAQD-DKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSIL 543
Query: 526 IKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGP 585
+KP + P VFSFL+PL+ +IWM ++ AY+GVS VLF+++RFSPYEW+ P +
Sbjct: 544 YRKPNGTNPSVFSFLNPLSPDIWMYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPG--- 600
Query: 586 SDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAF 645
S+ N F + NS WF +G+ MQQG ++ P++LS RI+GG+WWFFTLIIISSYTANLAAF
Sbjct: 601 SEVVENNFTLLNSFWFGMGSLMQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLAAF 660
Query: 646 LTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFT 705
LTVERM SPI+SA+DLAKQT+I YG + G+T FF++SKI+ +EKMW +M S++PS
Sbjct: 661 LTVERMESPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFM-SSKPSALV 719
Query: 706 RTTAEGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLG 765
+ EG+ R + +A L+EST EY+ QR C+ ++GG +DSKGYG+ TP GS
Sbjct: 720 KNNEEGIQRALTA--DYALLMESTTIEYVTQRN-CNLTQIGGLIDSKGYGIGTPMGSPYR 776
Query: 766 TPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGL 825
+ +A+L+L E L +K KWW G C +++ + SAL + + G+F +L GL
Sbjct: 777 DKITIAILQLQEEDKLHIMKEKWWRGSG-CPEEEN---KEASALGIQKIGGIFIVLAAGL 832
Query: 826 GLAMLVALIEFCYKSRAEAKRMKLTFSEAIRNKARLSIT 864
L++LVA+ EF YK R A+R + +F + ++ R S+T
Sbjct: 833 VLSVLVAVGEFVYKLRKTAEREQRSFCSTVADEIRFSLT 871
>gi|28416444 glutamate receptor, ionotropic, kainate 1 isoform 2
precursor [Homo sapiens]
Length = 905
Score = 588 bits (1517), Expect = e-168
Identities = 333/834 (39%), Positives = 490/834 (58%), Gaps = 36/834 (4%)
Query: 24 PSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPF---NLVPHVDNIETANSFAVT 80
P ++IGG+F ++ LA TS N + L + I +SF +
Sbjct: 34 PQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEAS 93
Query: 81 NAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFP---TEGESQFVLQLRP- 136
C Q + GV A+FG SV + S C+AL + I + + + F + L P
Sbjct: 94 RRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPD 153
Query: 137 --SLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVSY 194
++ A+L L+ +Y W +Y+ G LQ +++ + + + + N +
Sbjct: 154 YAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDA- 212
Query: 195 RQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIH 254
+ LL+E+ + +E + DC E IL+QI+ +G + YHY L + LE + +
Sbjct: 213 KPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRY 272
Query: 255 GGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP-----PKYTSALTYDGVLVMA 309
G N+TGF+L++ + P V ++++W + P ET +AL YD V ++A
Sbjct: 273 SGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVA 332
Query: 310 ETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHY-GR 368
S R ++ +S + PW G +K+ R GLTG++ F+ G
Sbjct: 333 --IASHRASQLTVS------SLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGL 384
Query: 369 RVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQ-DVPTLGNDTAAIENRTVVVTTIMESPY 427
R ++ +D+ LK G K+G WN L + + N T ++ NRT++VTTI+E PY
Sbjct: 385 RKDFDLDIISLKEEGTEKIGIWNSNSGLNMTDSNKDKSSNITDSLANRTLIVTTILEEPY 444
Query: 428 VMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVG 487
VMY+K+ + GND++EGYC+DL E++ +G Y + +VPDGKYGA++ D WNGMV
Sbjct: 445 VMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQN-DKGEWNGMVK 503
Query: 488 ELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEI 547
EL+ +A++A+APLTIT VRE+VIDFSKPFM+LGISI+ +KP + PGVFSFL+PL+ +I
Sbjct: 504 ELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDI 563
Query: 548 WMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFM 607
WM ++ A +GVS VLF+++RF+PYEW+ P + SD N F + NS WF +GA M
Sbjct: 564 WMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPD---SDVVENNFTLLNSFWFGVGALM 620
Query: 608 QQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEI 667
QQG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFLTVERM SPI+SA+DLAKQT+I
Sbjct: 621 QQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKI 680
Query: 668 AYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLE 727
YG + GST FF++SKI+ YEKMW +M S + + R + EG+ RV + +A L+E
Sbjct: 681 EYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTT--DYALLME 738
Query: 728 STMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSEAGVLDKLKNK 787
ST EY+ QR C+ ++GG +DSKGYGV TP GS + +A+L+L E G L +K K
Sbjct: 739 STSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEK 797
Query: 788 WWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 841
WW G C +D+ + SAL + N+ G+F +L GL L++ VA+ EF YKSR
Sbjct: 798 WWRGNG-CPEEDN---KEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSR 847
>gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2
precursor [Homo sapiens]
Length = 869
Score = 586 bits (1510), Expect = e-167
Identities = 341/868 (39%), Positives = 498/868 (57%), Gaps = 47/868 (5%)
Query: 3 IISRQIVLLFSGFW-GLAMGAFPSSVQIGGLF----IRNTDQEYTAFRLAIFLHNTS--- 54
+ R + LL W G + G ++ GG+F E AFR A+ N +
Sbjct: 12 VFRRTVKLLLCLLWIGYSQGT-THVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTL 70
Query: 55 -PNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSAL 113
PN + L I +SF + C Q S GV AIFG S + + S C+AL
Sbjct: 71 LPNTT-----LTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNAL 125
Query: 114 ---HISLITPSFPTEGESQFVLQLRP---SLRGALLSLLDHYEWNCFVFLYDTDRGYSIL 167
HI ++ + F + L P SL A+L L+ ++W +YD G L
Sbjct: 126 GVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRL 185
Query: 168 QAIMEKAGQNGWHVSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVS 227
Q +++ + + I + + LL+E+ R +E + DC E IL+Q ++
Sbjct: 186 QELIKAPSRYNLRLK-IRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALA 244
Query: 228 VGKHVKGYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRW--KKLDQR 285
+G + YHYI L + +E + + G N+TGF++++ V ++++W ++L
Sbjct: 245 MGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAP 304
Query: 286 EYPGSETPPKYTS---ALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQG 342
P S + + AL YD V V++ + + + + N PW G
Sbjct: 305 PKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQ--------CNRHKPWRFG 356
Query: 343 IDMERTLKQVRIQGLTGNVQFDHY-GRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQD 401
+K+ +GLTG + F+ G R ++ +DV LK G K+G W+ L + +
Sbjct: 357 TRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTES 416
Query: 402 VPTL-GNDTAAIENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGI 460
N T ++ NR+++VTTI+E PYV++KK+ + GND++EGYC+DL E++ +G
Sbjct: 417 QKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGF 476
Query: 461 KYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSL 520
Y+I +V DGKYGA+D WNGMV EL+ KA++A+APL IT VRE+VIDFSKPFM+L
Sbjct: 477 TYEIRLVEDGKYGAQDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTL 536
Query: 521 GISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPED 580
GISI+ +KP + PGVFSFL+PL+ +IWM I+ AY+GVS VLF+++RFSPYEW+ P
Sbjct: 537 GISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHP-- 594
Query: 581 GKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTA 640
SD N F + NS WF +GA MQQG ++ P++LS RIVGG+WWFFTLIIISSYTA
Sbjct: 595 -CNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTA 653
Query: 641 NLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAE 700
NLAAFLTVERM SPI+SA+DLAKQT+I YG ++ G+T FF++SKI+ Y+KMW +M S
Sbjct: 654 NLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRR 713
Query: 701 PSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPK 760
SV ++ EG+ RV S +AFL+EST E++ QR C+ ++GG +DSKGYGV TP
Sbjct: 714 QSVLVKSNEEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPM 770
Query: 761 GSSLGTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYI 820
GS + +A+L+L E G L +K KWW G C ++S + SAL + N+ G+F +
Sbjct: 771 GSPYRDKITIAILQLQEEGKLHMMKEKWWRGNG-CPEEES---KEASALGVQNIGGIFIV 826
Query: 821 LVGGLGLAMLVALIEFCYKSRAEAKRMK 848
L GL L++ VA+ EF YKS+ A+ K
Sbjct: 827 LAAGLVLSVFVAVGEFLYKSKKNAQLEK 854
>gi|4504117 glutamate receptor, ionotropic, kainate 1 isoform 1
precursor [Homo sapiens]
Length = 918
Score = 579 bits (1493), Expect = e-165
Identities = 333/849 (39%), Positives = 491/849 (57%), Gaps = 51/849 (6%)
Query: 24 PSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPF---NLVPHVDNIETANSFAVT 80
P ++IGG+F ++ LA TS N + L + I +SF +
Sbjct: 34 PQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEAS 93
Query: 81 NAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFP---TEGESQFVLQLRP- 136
C Q + GV A+FG SV + S C+AL + I + + + F + L P
Sbjct: 94 RRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPD 153
Query: 137 --SLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVSY 194
++ A+L L+ +Y W +Y+ G LQ +++ + + + + N +
Sbjct: 154 YAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDA- 212
Query: 195 RQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIH 254
+ LL+E+ + +E + DC E IL+QI+ +G + YHY L + LE + +
Sbjct: 213 KPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRY 272
Query: 255 GGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP-----PKYTSALTYDGVLVMA 309
G N+TGF+L++ + P V ++++W + P ET +AL YD V ++A
Sbjct: 273 SGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVA 332
Query: 310 ETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHY-GR 368
S R ++ +S + PW G +K+ R GLTG++ F+ G
Sbjct: 333 --IASHRASQLTVS------SLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGL 384
Query: 369 RVNYTMDVFELKSTGP---------------RKVGYWNDMDKLVLIQ-DVPTLGNDTAAI 412
R ++ +D+ LK G +K+G WN L + + N T ++
Sbjct: 385 RKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTDSNKDKSSNITDSL 444
Query: 413 ENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKY 472
NRT++VTTI+E PYVMY+K+ + GND++EGYC+DL E++ +G Y + +VPDGKY
Sbjct: 445 ANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKY 504
Query: 473 GARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 532
GA++ D WNGMV EL+ +A++A+APLTIT VRE+VIDFSKPFM+LGISI+ +KP +
Sbjct: 505 GAQN-DKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGT 563
Query: 533 KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNE 592
PGVFSFL+PL+ +IWM ++ A +GVS VLF+++RF+PYEW+ P + SD N
Sbjct: 564 NPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPD---SDVVENN 620
Query: 593 FGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV 652
F + NS WF +GA MQQG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFLTVERM
Sbjct: 621 FTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERME 680
Query: 653 SPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGV 712
SPI+SA+DLAKQT+I YG + GST FF++SKI+ YEKMW +M S + + R + EG+
Sbjct: 681 SPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGI 740
Query: 713 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAV 772
RV + +A L+EST EY+ QR C+ ++GG +DSKGYGV TP GS + +A+
Sbjct: 741 QRVLTT--DYALLMESTSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAI 797
Query: 773 LKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVA 832
L+L E G L +K KWW G C +D+ + SAL + N+ G+F +L GL L++ VA
Sbjct: 798 LQLQEEGKLHMMKEKWWRGNG-CPEEDN---KEASALGVENIGGIFIVLAAGLVLSVFVA 853
Query: 833 LIEFCYKSR 841
+ EF YKSR
Sbjct: 854 IGEFIYKSR 862
>gi|29029597 glutamate receptor KA2 precursor [Homo sapiens]
Length = 980
Score = 500 bits (1288), Expect = e-141
Identities = 307/844 (36%), Positives = 463/844 (54%), Gaps = 54/844 (6%)
Query: 45 RLAIFLHNTSPNAS-EAPFNLVPHVD--NIETANSFAVTNAFCSQYSRGVFAIFGLYDK- 100
RLA+ L N E P VD ++ + + T+ C +GV ++ G
Sbjct: 41 RLALALAREQINGIIEVPAKARVEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSP 100
Query: 101 RSVHTLTSFCSALHISLITPSFPTEGESQFV----LQLRPSLRGALLS---LLDHYEW-- 151
S T++ C I I Q++ + L PS L+ +L + +
Sbjct: 101 ASASTVSHICGEKEIPHIKVGPEETPRLQYLRFASVSLYPSNEDVSLAVSRILKSFNYPS 160
Query: 152 --------NCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVSYRQLLEELDR 203
C + L + RG+ I + + S +++ D + LL+E+
Sbjct: 161 ASLICAKAECLLRLEELVRGFLISKETL----------SVRMLDDSRDPT--PLLKEIRD 208
Query: 204 RQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIHGGANVTGFQ 263
+ +ID IL + +G Y YI+ + F + L+ + +N+ GF
Sbjct: 209 DKVSTIIIDANASISHLILRKASELGMTSAFYKYILTTMDFPILHLDGIVEDSSNILGFS 268
Query: 264 LVDFNTPMVIKLMDRWKKLDQREYPGSET--PPKYTSALTYDGVLVMAETFRSLRRQKID 321
+ + + P + + R + RE + T P ++AL +D V V+ R L R
Sbjct: 269 MFNTSHPFYPEFV-RSLNMSWRENCEASTYLGPALSAALMFDAVHVVVSAVRELNR---- 323
Query: 322 ISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVNYTMDVFELKS 381
S+ A W G + L+ V GLTG V+F+ G+R NYT+ + E
Sbjct: 324 -SQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKSR 382
Query: 382 TGPRKVGYWNDMDKLVLIQDVPTLG-NDTAAIENRTVVVTTIMESPYVMYKKNHEMFEGN 440
G R++G W L + TL N + + N+T+VVTTI+E+PYVM + N + GN
Sbjct: 383 QGHREIGVW--YSNRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALSGN 440
Query: 441 DKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAP 500
+++EG+CVD+ E+A+ + +Y++ +V DG YGA + + W GMVGEL+ KA++A+A
Sbjct: 441 ERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGAPEPNGS-WTGMVGELINRKADLAVAA 499
Query: 501 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 560
TIT RE+VIDFSKPFM+LGISI+ + KPG FSFLDP + +W+ ++ AY+ VS
Sbjct: 500 FTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSC 559
Query: 561 VLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSG 620
VLFL +R SPYEW+ P N++ + NSLWF +G FMQQG +I PR+LS
Sbjct: 560 VLFLAARLSPYEWYNPHP--CLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALST 617
Query: 621 RIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEF 680
R V GVWW FTLIIISSYTANLAAFLTV+RM P+ESA+DLA QT I YGT+ +GST F
Sbjct: 618 RCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTF 677
Query: 681 FRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYIEQRKPC 740
F+ S+ Y++MW YM+S +PSVF ++T EG+ARV S ++AFLLESTMNEY +R C
Sbjct: 678 FQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVLNS--RYAFLLESTMNEY-HRRLNC 734
Query: 741 DTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDS 800
+ ++GG LD+KGYG+ P GS + LA+L+L E L+ LK KWW + G C PK+
Sbjct: 735 NLTQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEILKRKWW-EGGRC-PKEE 792
Query: 801 GSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKLTFSEAIRNKAR 860
+ K L + N+ G+F +L+ GL +A+ VA++EF + +R A+ +++ + + + R
Sbjct: 793 DHRAK--GLGMENIGGIFIVLICGLIIAVFVAVMEFIWSTRRSAESEEVSVCQEMLQELR 850
Query: 861 LSIT 864
+++
Sbjct: 851 HAVS 854
>gi|29029595 glutamate receptor KA1 precursor [Homo sapiens]
Length = 956
Score = 494 bits (1273), Expect = e-139
Identities = 274/650 (42%), Positives = 391/650 (60%), Gaps = 25/650 (3%)
Query: 197 LLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIHGG 256
LL+E+ + +I IL + +G Y YI NL F ++ +
Sbjct: 203 LLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNLEFSLQRMDSLVDDR 262
Query: 257 ANVTGFQLVD----FNTPMVIKLMDRWKK-LDQREYPGSETPPKYTSALTYDGVLVMAET 311
N+ GF + + F L W++ D + G P +SAL +D V +
Sbjct: 263 VNILGFSIFNQSHAFFQEFAQSLNQSWQENCDHVPFTG----PALSSALLFDAVYAVVTA 318
Query: 312 FRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVN 371
+ L R S+ A W G + L+ V ++GLTG+++F+ G+R N
Sbjct: 319 VQELNR-----SQEIGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLTGHIEFNSKGQRSN 373
Query: 372 YTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIMESPYVMYK 431
Y + + + G R++G W+ + L + + N + + N T+VVTTI+E+PY+M K
Sbjct: 374 YALKILQFTRNGFRQIGQWHVAEGLSMDSHLYA-SNISDTLFNTTLVVTTILENPYLMLK 432
Query: 432 KNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELVY 491
NH+ EGND+YEG+CVD+ E+A+ + YKI +V DG YG +A+ W GMVGEL+
Sbjct: 433 GNHQEMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPEANGT-WTGMVGELIA 491
Query: 492 GKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCI 551
KA++A+A LTIT RE+VIDFSKPFM+LGISI+ + KPG FSFLDP + +W+ +
Sbjct: 492 RKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPGVWLFM 551
Query: 552 VFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGC 611
+ AY+ VS VLFLV+R +PYEW++ P +G + N++ + NSLWF +G FMQQG
Sbjct: 552 LLAYLAVSCVLFLVARLTPYEWYSPHP--CAQGRCNLLVNQYSLGNSLWFPVGGFMQQGS 609
Query: 612 DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGT 671
I+PR+LS R V GVWW FTLIIISSYTANLAAFLTV+RM PIES +DLA QT I YGT
Sbjct: 610 TIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDVPIESVDDLADQTAIEYGT 669
Query: 672 LDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMN 731
+ GS+ FF+ S+ Y++MW YM S +PSVF ++T EG+ARV S +AFLLESTMN
Sbjct: 670 IHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNS--NYAFLLESTMN 727
Query: 732 EYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSEAGVLDKLKNKWWYD 791
EY QR C+ ++GG LD+KGYG+ P GS +LA+L+L E L+ LK KWW +
Sbjct: 728 EYYRQRN-CNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILKRKWW-E 785
Query: 792 KGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 841
G+C PK+ + K L + N+ G+F +L+ GL +A+ +A++EF + R
Sbjct: 786 GGKC-PKEEDHRAK--GLGMENIGGIFVVLICGLIVAIFMAMLEFLWTLR 832
>gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens]
Length = 1007
Score = 333 bits (855), Expect = 3e-91
Identities = 237/867 (27%), Positives = 411/867 (47%), Gaps = 83/867 (9%)
Query: 25 SSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFC 84
S + IG +F + ++ FR A+ N + + + V ++ N F C
Sbjct: 25 SIIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTE-KITFSVTFVDGNNPFQAVQEAC 83
Query: 85 SQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLI-----TPSFPTEG--------ESQFV 131
++G+ A+ S +L S A+HI + T P G +
Sbjct: 84 ELMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYT 143
Query: 132 LQLRPS--LRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENF 189
L +RP L +L ++ Y W F+ YD++ +Q ++K Q G V+ VEN
Sbjct: 144 LSVRPPVYLHDVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKVENN 203
Query: 190 NDVSYRQL-----LEELDRRQE--KKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
+ L +EEL+R ++ ++ ++ ++ + ++V H+II N
Sbjct: 204 INKMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFITEVVETNLVAFDCHWIIINE 263
Query: 243 GFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPK------- 295
D+ ++ + ++ ++ P+ + R + + R + PK
Sbjct: 264 EINDVDVQELVR--RSIGRLTIIRQTFPVPQNISQRCFRGNHR-ISSTLCDPKDPFAQNM 320
Query: 296 -YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRI 354
++ YD VL++A F + S + C+ + PW G M T+K+ +
Sbjct: 321 EISNLYIYDTVLLLANAFHKKLEDRKWHSMASLS--CIRKNSKPWQGGRSMLETIKKGGV 378
Query: 355 QGLTGNVQFDHYGRRVNYTMDVF-----ELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDT 409
GLTG ++F G N ++ E G RK+G WN + L L N+
Sbjct: 379 SGLTGELEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKKLENNM 438
Query: 410 AAIENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPD 469
+ R V T++E P+VM +N + KY+G+ +D+ ++ ++G Y+I + PD
Sbjct: 439 RGVVLRVV---TVLEEPFVMVSEN--VLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPD 493
Query: 470 GKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKP 529
KYG+ D WNG+VGELV+ +A+I I+ LTIT RE V+DF+ +M + +++++
Sbjct: 494 HKYGSPQEDGT-WNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRRA 552
Query: 530 QKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQP 589
+K+ +F+ L P +W CI + V ++++L++ +P P
Sbjct: 553 EKTVD-MFACLAPFDLSLWACIAGTVLLVGLLVYLLNWLNP------------------P 593
Query: 590 PNEFG------IFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLA 643
+ G ++NS+WF G+F+QQG ++ +L+ R++ G WW F LI+ISSYTANLA
Sbjct: 594 RLQMGSMTSTTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLA 653
Query: 644 AFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKI------AVYEKMWTYMR 697
AFLT+ R+ S I+S +DL+KQTEI YGT+ + E R + ++Y +MW +
Sbjct: 654 AFLTITRIESSIQSLQDLSKQTEIPYGTVLDSAVYEHVRMKGLNPFERDSMYSQMWRMIN 713
Query: 698 SAEPSVFTRTTAEGVARVRKSK-GKFAFLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYG 755
+ S E A ++K K G +AF+ ++ + EY+ P C +G + +GYG
Sbjct: 714 RSNGS--ENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTIGNTVADRGYG 771
Query: 756 VATPKGSSLGTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDS-GSKDKTSALSLSNV 814
+A GS + +L+L + G +D LK+KWW G+C S +K K AL + +
Sbjct: 772 IALQHGSPYRDVFSQRILELQQNGDMDILKHKWWPKNGQCDLYSSVDTKQKGGALDIKSF 831
Query: 815 AGVFYILVGGLGLAMLVALIEFCYKSR 841
AGVF IL G+ L+ +A++E + R
Sbjct: 832 AGVFCILAAGIVLSCFIAMLETWWNKR 858
>gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [Homo
sapiens]
Length = 1009
Score = 332 bits (850), Expect = 1e-90
Identities = 245/864 (28%), Positives = 403/864 (46%), Gaps = 76/864 (8%)
Query: 25 SSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFC 84
S + IG +F N ++ F+LA+ + + + ++ + + IE N F C
Sbjct: 22 SIIHIGAIFEENAAKDDRVFQLAVSDLSLNDDILQSE-KITYSIKVIEANNPFQAVQEAC 80
Query: 85 SQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFVLQLRPS------- 137
++G+ A+ S + L S A+HI + G + L PS
Sbjct: 81 DLMTQGILALVTSTGCASANALQSLTDAMHIPHLFVQRNPGGSPRTACHLNPSPDGEAYT 140
Query: 138 --------LRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVEN- 188
L +L L+ W FV YD++ LQ+ +++A + G VS V+
Sbjct: 141 LASRPPVRLNDVMLRLVTELRWQKFVMFYDSEYDIRGLQSFLDQASRLGLDVSLQKVDKN 200
Query: 189 ----FNDVSYRQLLEELDRRQE--KKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
F + EEL+R ++ ++ ++ + + + + V K H++ N
Sbjct: 201 ISHVFTSLFTTMKTEELNRYRDTLRRAILLLSPQGAHSFINEAVETNLASKDSHWVFVNE 260
Query: 243 GFKDISLERFIHGGA-----------NVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSE 291
D + +H + Q N + L+ D +E G
Sbjct: 261 EISDPEILDLVHSALGRMTVVRQIFPSAKDNQKCTRNNHRISSLL-----CDPQE--GYL 313
Query: 292 TPPKYTSALTYDGVLVMAETF-RSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLK 350
+ ++ YD VL++A F R L +K N C+ PW G M T+K
Sbjct: 314 QMLQISNLYLYDSVLMLANAFHRKLEDRKWHSMASLN---CIRKSTKPWNGGRSMLDTIK 370
Query: 351 QVRIQGLTGNVQFDHYGRRVNYTMDVF-----ELKSTGPRKVGYWNDMDKLVLIQDVPTL 405
+ I GLTG ++F ++ E RK+ W+ L +
Sbjct: 371 KGHITGLTGVMEFREDSSNPYVQFEILGTTYSETFGKDMRKLATWDSEKGLNGSLQERPM 430
Query: 406 GNDTAAIENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIA 465
G+ ++ T+ V T++E P+VM +N + +Y+G+ +D+ +AK +G KY+I
Sbjct: 431 GS---RLQGLTLKVVTVLEEPFVMVAEN--ILGQPKRYKGFSIDVLDALAKALGFKYEIY 485
Query: 466 IVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIM 525
PDG+YG + +T WNGM+GEL+ +A++AI+ +TIT RE V+DFSK +M + I+
Sbjct: 486 QAPDGRYGHQLHNTS-WNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYSVGIL 544
Query: 526 IKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGP 585
IKKP++ K +FS P + +W CI A V V++F+++R +
Sbjct: 545 IKKPEE-KISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVR--------AQSAA 595
Query: 586 SDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAF 645
+P + +++W GAF+QQG + S S++ RIV G WW FTLI+ SSYTANLAAF
Sbjct: 596 QPRPSASATLHSAIWIVYGAFVQQGGESSVNSMAMRIVMGSWWLFTLIVCSSYTANLAAF 655
Query: 646 LTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRR------SKIAVYEKMW-TYMRS 698
LTV RM +PI + +DL+KQ E++YGT+ + E+FR + + + ++W T ++
Sbjct: 656 LTVSRMDNPIRTFQDLSKQVEMSYGTVRDSAVYEYFRAKGTNPLEQDSTFAELWRTISKN 715
Query: 699 AEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYIE-QRKPCDTMKVGGNLDSKGYGVA 757
+ +EG+ + + KG +AFL + + EY C +G ++ SKGYG+A
Sbjct: 716 GGADNCVSSPSEGIRKAK--KGNYAFLWDVAVVEYAALTDDDCSVTVIGNSISSKGYGIA 773
Query: 758 TPKGSSLGTPVNLAVLKLSEAGVLDKLKNKWWYDKGECG-PKDSGSKDKTSALSLSNVAG 816
GS + +L+L + G LD LK KWW G C + ++ +L L + AG
Sbjct: 774 LQHGSPYRDLFSQRILELQDTGDLDVLKQKWWPHMGRCDLTSHASAQADGKSLKLHSFAG 833
Query: 817 VFYILVGGLGLAMLVALIEFCYKS 840
VF IL GL LA LVA +E + S
Sbjct: 834 VFCILAIGLLLACLVAALELWWNS 857
>gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens]
Length = 901
Score = 220 bits (561), Expect = 4e-57
Identities = 178/624 (28%), Positives = 300/624 (48%), Gaps = 75/624 (12%)
Query: 295 KYTSALTYDGVLVMAETFRSL-RRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVR 353
K SA D V V+A+ L ++ I RG C+ N W G +R L +
Sbjct: 275 KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329
Query: 354 I-QGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAI 412
G+TG V+F+ G R + L++ +VG +N + + + G +T
Sbjct: 330 YADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKP 389
Query: 413 E----NRTVVVTTIMESPYVMYKKNHEMFEGNDKYE------------------------ 444
+ + + TI + P+V K + +G K E
Sbjct: 390 RGYQMSTRLKIVTIHQEPFVYVKPT--LSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSP 447
Query: 445 ---------GYCVDLASEIAKHIGIKYKIAIVPDGKYGARD----ADTKIWNGMVGELVY 491
G+C+DL ++A+ + Y++ +V DGK+G ++ ++ K WNGM+GEL+
Sbjct: 448 RHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLS 507
Query: 492 GKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCI 551
G+A++ +APLTI R + I+FSKPF G++I++KK + + + SF+ P +W+ +
Sbjct: 508 GQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLV 566
Query: 552 VFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGC 611
+ V+V+L+L+ RFSP+ E+ +E + + +++WFS G + G
Sbjct: 567 GLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEE-------DALTLSSAMWFSWGVLLNSGI 619
Query: 612 -DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EI 667
+ +PRS S RI+G VW F +II++SYTANLAAFL ++R I D + +
Sbjct: 620 GEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKF 679
Query: 668 AYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLE 727
Y T+ S +FRR ++ T R E + + AE + VR +K AF+ +
Sbjct: 680 IYATVKQSSVDIYFRRQ-----VELSTMYRHMEKHNY-ESAAEAIQAVRDNK-LHAFIWD 732
Query: 728 STMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSEAGVLDKLKNK 787
S + E+ E + CD + G G+G+ K S V+L++LK E G ++ L +K
Sbjct: 733 SAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDL-DK 790
Query: 788 WWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRM 847
W EC DS S + + L+ N+AGVF ++ GG+ + + IE YK +A+R
Sbjct: 791 TWVRYQEC---DSRS-NAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRK 846
Query: 848 KLTFSEAIRNKARLSITGSVGENG 871
++ + A N R ++ + G G
Sbjct: 847 QMQLAFAAVNVWRKNLQSTGGGRG 870
>gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens]
Length = 938
Score = 218 bits (555), Expect = 2e-56
Identities = 185/641 (28%), Positives = 308/641 (48%), Gaps = 79/641 (12%)
Query: 295 KYTSALTYDGVLVMAETFRSL-RRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVR 353
K SA D V V+A+ L ++ I RG C+ N W G +R L +
Sbjct: 275 KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329
Query: 354 I-QGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAI 412
G+TG V+F+ G R + L++ +VG +N + + + G +T
Sbjct: 330 YADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKP 389
Query: 413 E----NRTVVVTTIMESPYVMYKKNHEMFEGNDKYE------------------------ 444
+ + + TI + P+V K + +G K E
Sbjct: 390 RGYQMSTRLKIVTIHQEPFVYVKPT--LSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSP 447
Query: 445 ---------GYCVDLASEIAKHIGIKYKIAIVPDGKYGARD----ADTKIWNGMVGELVY 491
G+C+DL ++A+ + Y++ +V DGK+G ++ ++ K WNGM+GEL+
Sbjct: 448 RHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLS 507
Query: 492 GKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCI 551
G+A++ +APLTI R + I+FSKPF G++I++KK + + + SF+ P +W+ +
Sbjct: 508 GQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLV 566
Query: 552 VFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGC 611
+ V+V+L+L+ RFSP+ E+ +E + + +++WFS G + G
Sbjct: 567 GLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEE-------DALTLSSAMWFSWGVLLNSGI 619
Query: 612 -DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EI 667
+ +PRS S RI+G VW F +II++SYTANLAAFL ++R I D + +
Sbjct: 620 GEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKF 679
Query: 668 AYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLE 727
Y T+ S +FRR ++ T R E + + AE + VR +K AF+ +
Sbjct: 680 IYATVKQSSVDIYFRRQ-----VELSTMYRHMEKHNY-ESAAEAIQAVRDNK-LHAFIWD 732
Query: 728 STMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSEAGVLDKLKNK 787
S + E+ E + CD + G G+G+ K S V+L++LK E G ++ L +K
Sbjct: 733 SAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDL-DK 790
Query: 788 WWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRM 847
W EC DS S + + L+ N+AGVF ++ GG+ + + IE YK +A+R
Sbjct: 791 TWVRYQEC---DSRS-NAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRK 846
Query: 848 KLTFSEAIRNKARLSITGSVGENGRVLTPDCPKAVHTGTAI 888
++ + A N R ++ ++GR PD PK T AI
Sbjct: 847 QMQLAFAAVNVWRKNLQDR--KSGRA-EPD-PKKKATFRAI 883
>gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens]
Length = 885
Score = 218 bits (554), Expect = 3e-56
Identities = 176/616 (28%), Positives = 297/616 (48%), Gaps = 75/616 (12%)
Query: 295 KYTSALTYDGVLVMAETFRSL-RRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVR 353
K SA D V V+A+ L ++ I RG C+ N W G +R L +
Sbjct: 275 KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 329
Query: 354 I-QGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAI 412
G+TG V+F+ G R + L++ +VG +N + + + G +T
Sbjct: 330 YADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKP 389
Query: 413 E----NRTVVVTTIMESPYVMYKKNHEMFEGNDKYE------------------------ 444
+ + + TI + P+V K + +G K E
Sbjct: 390 RGYQMSTRLKIVTIHQEPFVYVKPT--LSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSP 447
Query: 445 ---------GYCVDLASEIAKHIGIKYKIAIVPDGKYGARD----ADTKIWNGMVGELVY 491
G+C+DL ++A+ + Y++ +V DGK+G ++ ++ K WNGM+GEL+
Sbjct: 448 RHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLS 507
Query: 492 GKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCI 551
G+A++ +APLTI R + I+FSKPF G++I++KK + + + SF+ P +W+ +
Sbjct: 508 GQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLV 566
Query: 552 VFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGC 611
+ V+V+L+L+ RFSP+ E+ +E + + +++WFS G + G
Sbjct: 567 GLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEE-------DALTLSSAMWFSWGVLLNSGI 619
Query: 612 -DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EI 667
+ +PRS S RI+G VW F +II++SYTANLAAFL ++R I D + +
Sbjct: 620 GEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKF 679
Query: 668 AYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLE 727
Y T+ S +FRR ++ T R E + + AE + VR +K AF+ +
Sbjct: 680 IYATVKQSSVDIYFRRQ-----VELSTMYRHMEKHNY-ESAAEAIQAVRDNK-LHAFIWD 732
Query: 728 STMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSEAGVLDKLKNK 787
S + E+ E + CD + G G+G+ K S V+L++LK E G ++ L +K
Sbjct: 733 SAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDL-DK 790
Query: 788 WWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRM 847
W EC DS S + + L+ N+AGVF ++ GG+ + + IE YK +A+R
Sbjct: 791 TWVRYQEC---DSRS-NAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRK 846
Query: 848 KLTFSEAIRNKARLSI 863
++ + A N R ++
Sbjct: 847 QMQLAFAAVNVWRKNL 862
>gi|55770854 N-methyl-D-aspartate receptor subunit 2C precursor
[Homo sapiens]
Length = 1233
Score = 194 bits (492), Expect = 4e-49
Identities = 214/883 (24%), Positives = 364/883 (41%), Gaps = 126/883 (14%)
Query: 11 LFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDN 70
LF + GL G + + +F ++ FR + T + + P + P
Sbjct: 14 LFGAWAGLGPGQGEQGMTVAVVF-SSSGPPQAQFRARL----TPQSFLDLPLEIQPLTVG 68
Query: 71 IETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHT------LTSFCSALHISLITPS--- 121
+ T N ++ C G + G+ + +V T L S H+ +++ S
Sbjct: 69 VNTTNPSSLLTQICGLL--GAAHVHGIVFEDNVDTEAVAQILDFISSQTHVPILSISGGS 126
Query: 122 ----FPTEGESQFVLQLRPSLRG---ALLSLLDHYEWNCFVFLYDTDRGYSI----LQAI 170
P E S F LQL SL L +L+ Y+W+ F + G+++ ++A+
Sbjct: 127 AVVLTPKEPGSAF-LQLGVSLEQQLQVLFKVLEEYDWSAFAVITSLHPGHALFLEGVRAV 185
Query: 171 MEKAGQNGWHVSAICVENFNDVSYRQLLEELDRRQEKK-FVIDCEIERLQNILEQIVSVG 229
+ A W + + R + L R+ + FV C E + + + G
Sbjct: 186 AD-ASHVSWRLLDVVTLELGPGGPRARTQRLLRQLDAPVFVAYCSREEAEVLFAEAAQAG 244
Query: 230 KHVKGYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPG 289
G+ +++ NL T F ++ + + W+ L R+
Sbjct: 245 LVGPGHVWLVPNLALGS-------------TDAPPATFPVGLISVVTESWR-LSLRQK-- 288
Query: 290 SETPPKYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTL 349
DGV ++A S RQ + AGDC +P R L
Sbjct: 289 -----------VRDGVAILALGAHSYWRQHGTLP--APAGDCRVHPGPVSPAREAFYRHL 335
Query: 350 KQVRIQGLTGNVQFDHYGRRVNYTMDVFELKSTGP-RKVGYWNDMDKLVLIQDVPTLGND 408
V +G + F G V TM V L VG W + VL P
Sbjct: 336 LNVTWEGR--DFSFSPGGYLVQPTMVVIALNRHRLWEMVGRW---EHGVLYMKYPVWPRY 390
Query: 409 TAA----IENRTVVVTTIMESPYVMYKK-------------------NHEMFEGNDK--- 442
+A+ +++R + V T+ E P+V+ + NH G+
Sbjct: 391 SASLQPVVDSRHLTVATLEERPFVIVESPDPGTGGCVPNTVPCRRQSNHTFSSGDVAPYT 450
Query: 443 ---YEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIA 499
+G+C+D+ ++A+ + Y + +V +GK+G R +WNGM+GE+ Y +A++AI
Sbjct: 451 KLCCKGFCIDILKKLARVVKFSYDLYLVTNGKHGKRVRG--VWNGMIGEVYYKRADMAIG 508
Query: 500 PLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGV 558
LTI R E++DFS PF+ GIS+M+ + +FL+P + +W M V V
Sbjct: 509 SLTINEERSEIVDFSVPFVETGISVMVAR-SNGTVSPSAFLEPYSPAVWVMMFVMCLTVV 567
Query: 559 SVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDI-SPRS 617
++ +F+ FSP ++ K G F I S+W I +PR
Sbjct: 568 AITVFMFEYFSPVSYNQNLTRGKKSGGP-----AFTIGKSVWLLWALVFNNSVPIENPRG 622
Query: 618 LSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGT 671
+ +I+ VW FF +I ++SYTANLAAF+ E+ + + D Q +GT
Sbjct: 623 TTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQRPQDQYPPFRFGT 682
Query: 672 LDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMN 731
+ +GST+ R + Y M T+M F + + E K AF+ ++ +
Sbjct: 683 VPNGSTERNIRSN----YRDMHTHMVK-----FNQRSVEDALTSLKMGKLDAFIYDAAVL 733
Query: 732 EYIEQR-KPCDTMKVGGN--LDSKGYGVATPKGSSLGTPVNLAVLKLSEAGVLDKLKNKW 788
Y+ + + C + +G + GYG+A K S ++LA+L+ G KL+ W
Sbjct: 734 NYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQFLGDGETQKLETVW 793
Query: 789 WYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLV 831
G C ++ ++ +S L + N+AGVFY+L+ +GLA+LV
Sbjct: 794 L--SGIC--QNEKNEVMSSKLDIDNMAGVFYMLLVAMGLALLV 832
>gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor
[Homo sapiens]
Length = 1484
Score = 191 bits (486), Expect = 2e-48
Identities = 197/794 (24%), Positives = 337/794 (42%), Gaps = 117/794 (14%)
Query: 99 DKRSVHTLTSFCSALHISLITPSFPTEG----------ESQFVLQLRPSLR---GALLSL 145
D+ ++ + F SA +TP G ES Q PS+ +L++
Sbjct: 104 DQEAIAQILDFISA---QTLTPILGIHGGSSMIMADKDESSMFFQFGPSIEQQASVMLNI 160
Query: 146 LDHYEWNCFVFLYDTDRGYSILQAIMEKAGQN---GWHVSAICVENFN-DVSYRQLLEEL 201
++ Y+W F + GY + +N GW + + + + + D ++ +L
Sbjct: 161 MEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKIQNQL 220
Query: 202 DRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIHGGANVTG 261
+ Q ++ C E I E SVG GY +I+ +L D T
Sbjct: 221 KKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGD-------------TD 267
Query: 262 FQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSALTYDGVLVMAETFRSLRRQKID 321
+F T ++ D W +Y A DG+ ++ + +
Sbjct: 268 TVPAEFPTGLISVSYDEW------DYG--------LPARVRDGIAIITTAASDMLSEHSF 313
Query: 322 ISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVNYTMDVFEL-K 380
I ++ C Q + R L V +G N+ F G +++ + + L K
Sbjct: 314 IPEPKSS--CYNTHEKRIYQSNMLNRYLINVTFEGR--NLSFSEDGYQMHPKLVIILLNK 369
Query: 381 STGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIMESPYVMY---------- 430
+VG W D + P + +T E+ + + T+ E+P+V+
Sbjct: 370 ERKWERVGKWKDKSLQMKYYVWPRMCPETEEQEDDHLSIVTLEEAPFVIVESVDPLSGTC 429
Query: 431 ---------------KKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGAR 475
K + E +G+C+D+ +I+K + Y + +V +GK+G +
Sbjct: 430 MRNTVPCQKRIVTENKTDEEPGYIKKCCKGFCIDILKKISKSVKFTYDLYLVTNGKHGKK 489
Query: 476 DADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 535
T WNGM+GE+V +A +A+ LTI R EV+DFS PF+ GIS+M+ +
Sbjct: 490 INGT--WNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSR-SNGTVS 546
Query: 536 VFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKE--GPSDQPPNE 592
+FL+P + ++W M V I +V +F+ FSP ++ DG+E GPS
Sbjct: 547 PSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYN-RCLADGREPGGPS------ 599
Query: 593 FGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERM 651
F I ++W G + +P+ + +I+ VW FF +I ++SYTANLAAF+ E
Sbjct: 600 FTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEY 659
Query: 652 VSPIESAEDLAKQ------TEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFT 705
V + D Q +GT+ +GST+ R + Y +M YM F
Sbjct: 660 VDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNN----YAEMHAYM-----GKFN 710
Query: 706 RTTAEGVARVRKSKGKFAFLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGVATPKGS 762
+ + K+ AF+ ++ + Y+ R + C + +G S GYG+A K S
Sbjct: 711 QRGVDDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDS 770
Query: 763 SLGTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILV 822
V+LA+L+L G +++L+ W G C + ++ +S L + N+AGVFY+
Sbjct: 771 GWKRQVDLAILQLFGDGEMEELEALWL--TGIC--HNEKNEVMSSQLDIDNMAGVFYM-- 824
Query: 823 GGLGLAMLVALIEF 836
LG AM ++LI F
Sbjct: 825 --LGAAMALSLITF 836
>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor
[Homo sapiens]
Length = 1336
Score = 174 bits (441), Expect = 3e-43
Identities = 121/400 (30%), Positives = 206/400 (51%), Gaps = 34/400 (8%)
Query: 444 EGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTI 503
+G+C+D+ +A IG Y + +V +GK+G + +WNGM+GE+ Y +A++AI LTI
Sbjct: 485 KGFCIDILKRLAHTIGFSYDLYLVTNGKHGKKIDG--VWNGMIGEVFYQRADMAIGSLTI 542
Query: 504 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVL 562
R E++DFS PF+ GIS+M+ + +FL+P + +W M V V+V +
Sbjct: 543 NEERSEIVDFSVPFVETGISVMVAR-SNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTV 601
Query: 563 FLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGR 621
F+ SP ++ + G S F I S+W + +PR + +
Sbjct: 602 FIFEYLSPVGYNRSLATGKRPGGS-----TFTIGKSIWLLWALVFNNSVPVENPRGTTSK 656
Query: 622 IVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLDSG 675
I+ VW FF +I ++SYTANLAAF+ E V + D Q + +GT+ +G
Sbjct: 657 IMVLVWAFFAVIFLASYTANLAAFMIQEEYVDTVSGLSDRKFQRPQEQYPPLKFGTVPNG 716
Query: 676 STKEFFRRSKIAVYEKMWTYM-RSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYI 734
ST++ R + Y M +YM R +P V E + +++ K AF+ ++ + Y+
Sbjct: 717 STEKNIRSN----YPDMHSYMVRYNQPRV-----EEALTQLKAGK-LDAFIYDAAVLNYM 766
Query: 735 EQR-KPCDTMKVGGN--LDSKGYGVATPKGSSLGTPVNLAVLKLSEAGVLDKLKNKWWYD 791
++ + C + +G + GYG+A KGS P++LA+L+ ++ L+ W
Sbjct: 767 ARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEMLERLWL-- 824
Query: 792 KGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLV 831
G C + + +S L + N+AGVFY+L+ +GL++LV
Sbjct: 825 SGIC--HNDKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLV 862
>gi|197313638 N-methyl-D-aspartate receptor subunit 2A isoform 2
precursor [Homo sapiens]
Length = 1281
Score = 172 bits (436), Expect = 1e-42
Identities = 120/410 (29%), Positives = 206/410 (50%), Gaps = 40/410 (9%)
Query: 444 EGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTI 503
+G+C+D+ ++++ + Y + +V +GK+G + +WNGM+GE+VY +A +A+ LTI
Sbjct: 457 KGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV--NNVWNGMIGEVVYQRAVMAVGSLTI 514
Query: 504 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVL 562
R EV+DFS PF+ GIS+M+ + +FL+P + +W M V I ++ +
Sbjct: 515 NEERSEVVDFSVPFVETGISVMVSR-SNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAV 573
Query: 563 FLVSRFSPYEWHTEEPE-DGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSG 620
F+ FSP ++ + GPS F I ++W G + +P+ +
Sbjct: 574 FVFEYFSPVGYNRNLAKGKAPHGPS------FTIGKAIWLLWGLVFNNSVPVQNPKGTTS 627
Query: 621 RIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLDS 674
+I+ VW FF +I ++SYTANLAAF+ E V + D Q +GT+ +
Sbjct: 628 KIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPN 687
Query: 675 GSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGV--ARVRKSKGKF-AFLLESTMN 731
GST+ R + Y M YM T+ +GV A V GK AF+ ++ +
Sbjct: 688 GSTERNIRNN----YPYMHQYM--------TKFNQKGVEDALVSLKTGKLDAFIYDAAVL 735
Query: 732 EYIEQR-KPCDTMKVGGN--LDSKGYGVATPKGSSLGTPVNLAVLKLSEAGVLDKLKNKW 788
Y R + C + +G + GYG+A KGS ++LA+L+ G +++L+ W
Sbjct: 736 NYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLW 795
Query: 789 WYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 838
G C + ++ +S L + N+AGVFY+L + L+++ + E +
Sbjct: 796 L--TGIC--HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLF 841
>gi|197313636 N-methyl-D-aspartate receptor subunit 2A isoform 1
precursor [Homo sapiens]
Length = 1464
Score = 172 bits (436), Expect = 1e-42
Identities = 120/410 (29%), Positives = 206/410 (50%), Gaps = 40/410 (9%)
Query: 444 EGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTI 503
+G+C+D+ ++++ + Y + +V +GK+G + +WNGM+GE+VY +A +A+ LTI
Sbjct: 457 KGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV--NNVWNGMIGEVVYQRAVMAVGSLTI 514
Query: 504 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVL 562
R EV+DFS PF+ GIS+M+ + +FL+P + +W M V I ++ +
Sbjct: 515 NEERSEVVDFSVPFVETGISVMVSR-SNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAV 573
Query: 563 FLVSRFSPYEWHTEEPE-DGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSG 620
F+ FSP ++ + GPS F I ++W G + +P+ +
Sbjct: 574 FVFEYFSPVGYNRNLAKGKAPHGPS------FTIGKAIWLLWGLVFNNSVPVQNPKGTTS 627
Query: 621 RIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLDS 674
+I+ VW FF +I ++SYTANLAAF+ E V + D Q +GT+ +
Sbjct: 628 KIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPN 687
Query: 675 GSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGV--ARVRKSKGKF-AFLLESTMN 731
GST+ R + Y M YM T+ +GV A V GK AF+ ++ +
Sbjct: 688 GSTERNIRNN----YPYMHQYM--------TKFNQKGVEDALVSLKTGKLDAFIYDAAVL 735
Query: 732 EYIEQR-KPCDTMKVGGN--LDSKGYGVATPKGSSLGTPVNLAVLKLSEAGVLDKLKNKW 788
Y R + C + +G + GYG+A KGS ++LA+L+ G +++L+ W
Sbjct: 736 NYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLW 795
Query: 789 WYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 838
G C + ++ +S L + N+AGVFY+L + L+++ + E +
Sbjct: 796 L--TGIC--HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLF 841
>gi|4504125 N-methyl-D-aspartate receptor subunit 2A isoform 1
precursor [Homo sapiens]
Length = 1464
Score = 172 bits (436), Expect = 1e-42
Identities = 120/410 (29%), Positives = 206/410 (50%), Gaps = 40/410 (9%)
Query: 444 EGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTI 503
+G+C+D+ ++++ + Y + +V +GK+G + +WNGM+GE+VY +A +A+ LTI
Sbjct: 457 KGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKV--NNVWNGMIGEVVYQRAVMAVGSLTI 514
Query: 504 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVL 562
R EV+DFS PF+ GIS+M+ + +FL+P + +W M V I ++ +
Sbjct: 515 NEERSEVVDFSVPFVETGISVMVSR-SNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAV 573
Query: 563 FLVSRFSPYEWHTEEPE-DGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSG 620
F+ FSP ++ + GPS F I ++W G + +P+ +
Sbjct: 574 FVFEYFSPVGYNRNLAKGKAPHGPS------FTIGKAIWLLWGLVFNNSVPVQNPKGTTS 627
Query: 621 RIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLDS 674
+I+ VW FF +I ++SYTANLAAF+ E V + D Q +GT+ +
Sbjct: 628 KIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPN 687
Query: 675 GSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGV--ARVRKSKGKF-AFLLESTMN 731
GST+ R + Y M YM T+ +GV A V GK AF+ ++ +
Sbjct: 688 GSTERNIRNN----YPYMHQYM--------TKFNQKGVEDALVSLKTGKLDAFIYDAAVL 735
Query: 732 EYIEQR-KPCDTMKVGGN--LDSKGYGVATPKGSSLGTPVNLAVLKLSEAGVLDKLKNKW 788
Y R + C + +G + GYG+A KGS ++LA+L+ G +++L+ W
Sbjct: 736 NYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLW 795
Query: 789 WYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 838
G C + ++ +S L + N+AGVFY+L + L+++ + E +
Sbjct: 796 L--TGIC--HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLF 841
>gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
[Homo sapiens]
Length = 1043
Score = 155 bits (393), Expect = 1e-37
Identities = 114/406 (28%), Positives = 203/406 (50%), Gaps = 40/406 (9%)
Query: 445 GYCVDLASEIAKHIGIKYKIAIVPDGKYGA-RDADTKIWNGMVGELVYGKAEIAIAPLTI 503
GYC+DL +A+ +++ +V DGKYGA RD W G+VG+L+ G+A +A+ +I
Sbjct: 478 GYCIDLLERLAEDTPFDFELYLVGDGKYGALRDGR---WTGLVGDLLAGRAHMAVTSFSI 534
Query: 504 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLF 563
R +V+DF+ PF S + IM++ + P + +F+ PL + W +GV L
Sbjct: 535 NSARSQVVDFTSPFFSTSLGIMVRARDTASP-IGAFMWPLHWSTW-------LGVFAALH 586
Query: 564 LVSRF-SPYEWHTEEPEDGKEGPSDQPPNEFGIFN-----SLWFSLGAFMQQGCDISPRS 617
L + F + YEW + G + + N +F+ +L +++ F + +P+
Sbjct: 587 LTALFLTVYEWRS------PYGLTPRGRNRSTVFSYSSALNLCYAI-LFRRTVSSKTPKC 639
Query: 618 LSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLA---KQTEIAYGTLDS 674
+GR++ +W F L+++SSYTANLAA + ++ + D +GT+
Sbjct: 640 PTGRLLMNLWAIFCLLVLSSYTANLAAVMVGDKTFEELSGIHDPKLHHPAQGFRFGTVWE 699
Query: 675 GSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKF-AFLLESTMNEY 733
S + + ++S + M +MR TT GVA + K AF+++ ++ +Y
Sbjct: 700 SSAEAYIKKS----FPDMHAHMRRHS----APTTPRGVAMLTSDPPKLNAFIMDKSLLDY 751
Query: 734 -IEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGTPVNLAVLKLSEAGVLDKLKNKWWYDK 792
+ C + VG +GYG+ P+ S L + ++ + + +G +D L +K WY
Sbjct: 752 EVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDK-WYKM 810
Query: 793 GECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 838
CG K + +T +S+ + AG+F +L GLG A+L +L E +
Sbjct: 811 VPCG-KRVFAVTETLQMSIYHFAGLFVLLCLGLGSALLSSLGEHAF 855
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,083,388
Number of Sequences: 37866
Number of extensions: 1386844
Number of successful extensions: 3209
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3020
Number of HSP's gapped (non-prelim): 52
length of query: 902
length of database: 18,247,518
effective HSP length: 111
effective length of query: 791
effective length of database: 14,044,392
effective search space: 11109114072
effective search space used: 11109114072
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.