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Search of human proteins with 16418457
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16418457 solute carrier family 26, member 8 isoform a [Homo
sapiens]
(970 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16418457 solute carrier family 26, member 8 isoform a [Homo s... 1918 0.0
gi|20336285 solute carrier family 26, member 8 isoform b [Homo s... 1299 0.0
gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo s... 373 e-103
gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo s... 372 e-102
gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo s... 371 e-102
gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo s... 349 8e-96
gi|4557535 solute carrier family 26, member 3 [Homo sapiens] 314 2e-85
gi|16418413 solute carrier family 26, member 9 isoform a [Homo s... 308 2e-83
gi|217272867 solute carrier family 26, member 9 isoform b [Homo ... 308 2e-83
gi|4505697 pendrin [Homo sapiens] 292 1e-78
gi|45827800 prestin isoform b [Homo sapiens] 282 9e-76
gi|39752683 prestin isoform a [Homo sapiens] 282 9e-76
gi|100913030 solute carrier family 26 member 2 [Homo sapiens] 253 5e-67
gi|45827802 prestin isoform c [Homo sapiens] 248 3e-65
gi|47131207 solute carrier family 26, member 1 isoform a [Homo s... 234 4e-61
gi|20336272 solute carrier family 26, member 1 isoform a [Homo s... 234 4e-61
gi|16306483 solute carrier family 26, member 7 isoform a [Homo s... 195 2e-49
gi|20336282 solute carrier family 26, member 7 isoform b [Homo s... 195 2e-49
gi|217272870 solute carrier family 26, member 9 isoform c [Homo ... 166 7e-41
gi|65506789 solute carrier family 26, member 10 [Homo sapiens] 157 6e-38
gi|85540447 solute carrier family 26, member 11 [Homo sapiens] 126 1e-28
gi|45827804 prestin isoform d [Homo sapiens] 122 1e-27
gi|20336274 solute carrier family 26, member 1 isoform b [Homo s... 65 2e-10
gi|4505419 nucleolar protein 3 [Homo sapiens] 51 6e-06
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 44 6e-04
gi|21361639 DIPB protein [Homo sapiens] 44 7e-04
gi|83977459 pleckstrin homology-like domain, family A, member 1 ... 44 7e-04
gi|7706589 GNAS complex locus NESP55 [Homo sapiens] 43 0.001
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 43 0.002
gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 ... 42 0.003
>gi|16418457 solute carrier family 26, member 8 isoform a [Homo
sapiens]
Length = 970
Score = 1918 bits (4968), Expect = 0.0
Identities = 970/970 (100%), Positives = 970/970 (100%)
Query: 1 MAQLERSAISGFSSKSRRNSFAYDVKREVYNEETFQQEHKRKASSSGNMNINITTFRHHV 60
MAQLERSAISGFSSKSRRNSFAYDVKREVYNEETFQQEHKRKASSSGNMNINITTFRHHV
Sbjct: 1 MAQLERSAISGFSSKSRRNSFAYDVKREVYNEETFQQEHKRKASSSGNMNINITTFRHHV 60
Query: 61 QCRCSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQL 120
QCRCSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQL
Sbjct: 61 QCRCSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQL 120
Query: 121 IPPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSFVKN 180
IPPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSFVKN
Sbjct: 121 IPPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSFVKN 180
Query: 181 EFSAPSYLMGYNKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHI 240
EFSAPSYLMGYNKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHI
Sbjct: 181 EFSAPSYLMGYNKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHI 240
Query: 241 MLSQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRIS 300
MLSQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRIS
Sbjct: 241 MLSQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRIS 300
Query: 301 FNQYPIEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQ 360
FNQYPIEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQ
Sbjct: 301 FNQYPIEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQ 360
Query: 361 AFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTII 420
AFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTII
Sbjct: 361 AFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTII 420
Query: 421 QDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLW 480
QDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLW
Sbjct: 421 QDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLW 480
Query: 481 RQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRS 540
RQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRS
Sbjct: 481 RQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRS 540
Query: 541 INDYREIITIPGVKIFQCCSSITFVNVYYLKHKLLKEVDMVKVPLKEEEIFSLFNSSDTN 600
INDYREIITIPGVKIFQCCSSITFVNVYYLKHKLLKEVDMVKVPLKEEEIFSLFNSSDTN
Sbjct: 541 INDYREIITIPGVKIFQCCSSITFVNVYYLKHKLLKEVDMVKVPLKEEEIFSLFNSSDTN 600
Query: 601 LQGGKICRCFCNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASEDQ 660
LQGGKICRCFCNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASEDQ
Sbjct: 601 LQGGKICRCFCNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASEDQ 660
Query: 661 VPYTVSSVSQKNQGQQYEEVEEVWLPNNSSRNSSPGLPDVAESQGRRSLIPYSDASLLPS 720
VPYTVSSVSQKNQGQQYEEVEEVWLPNNSSRNSSPGLPDVAESQGRRSLIPYSDASLLPS
Sbjct: 661 VPYTVSSVSQKNQGQQYEEVEEVWLPNNSSRNSSPGLPDVAESQGRRSLIPYSDASLLPS 720
Query: 721 VHTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGIT 780
VHTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGIT
Sbjct: 721 VHTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGIT 780
Query: 781 KTQLFLSVHDAVLFALSRKVIGSSELSIDESETVIRETYSETDKNDNSRYKMSSSFLGSQ 840
KTQLFLSVHDAVLFALSRKVIGSSELSIDESETVIRETYSETDKNDNSRYKMSSSFLGSQ
Sbjct: 781 KTQLFLSVHDAVLFALSRKVIGSSELSIDESETVIRETYSETDKNDNSRYKMSSSFLGSQ 840
Query: 841 KNVSPGFIKIQQPVEEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEM 900
KNVSPGFIKIQQPVEEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEM
Sbjct: 841 KNVSPGFIKIQQPVEEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEM 900
Query: 901 EPQPETEPEMEPNPKSRPRAHTFPQQRYWPMYHPSMASTQSQTQTRTWSVERRRHPMDSY 960
EPQPETEPEMEPNPKSRPRAHTFPQQRYWPMYHPSMASTQSQTQTRTWSVERRRHPMDSY
Sbjct: 901 EPQPETEPEMEPNPKSRPRAHTFPQQRYWPMYHPSMASTQSQTQTRTWSVERRRHPMDSY 960
Query: 961 SPEGNSNEDV 970
SPEGNSNEDV
Sbjct: 961 SPEGNSNEDV 970
>gi|20336285 solute carrier family 26, member 8 isoform b [Homo
sapiens]
Length = 865
Score = 1299 bits (3362), Expect = 0.0
Identities = 656/656 (100%), Positives = 656/656 (100%)
Query: 315 IIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIF 374
IIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIF
Sbjct: 210 IIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIF 269
Query: 375 LGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLV 434
LGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLV
Sbjct: 270 LGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLV 329
Query: 435 GAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWMMTF 494
GAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWMMTF
Sbjct: 330 GAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWMMTF 389
Query: 495 SSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREIITIPGVK 554
SSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREIITIPGVK
Sbjct: 390 SSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREIITIPGVK 449
Query: 555 IFQCCSSITFVNVYYLKHKLLKEVDMVKVPLKEEEIFSLFNSSDTNLQGGKICRCFCNCD 614
IFQCCSSITFVNVYYLKHKLLKEVDMVKVPLKEEEIFSLFNSSDTNLQGGKICRCFCNCD
Sbjct: 450 IFQCCSSITFVNVYYLKHKLLKEVDMVKVPLKEEEIFSLFNSSDTNLQGGKICRCFCNCD 509
Query: 615 DLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASEDQVPYTVSSVSQKNQG 674
DLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASEDQVPYTVSSVSQKNQG
Sbjct: 510 DLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASEDQVPYTVSSVSQKNQG 569
Query: 675 QQYEEVEEVWLPNNSSRNSSPGLPDVAESQGRRSLIPYSDASLLPSVHTIILDFSMVHYV 734
QQYEEVEEVWLPNNSSRNSSPGLPDVAESQGRRSLIPYSDASLLPSVHTIILDFSMVHYV
Sbjct: 570 QQYEEVEEVWLPNNSSRNSSPGLPDVAESQGRRSLIPYSDASLLPSVHTIILDFSMVHYV 629
Query: 735 DSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGITKTQLFLSVHDAVLF 794
DSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGITKTQLFLSVHDAVLF
Sbjct: 630 DSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGITKTQLFLSVHDAVLF 689
Query: 795 ALSRKVIGSSELSIDESETVIRETYSETDKNDNSRYKMSSSFLGSQKNVSPGFIKIQQPV 854
ALSRKVIGSSELSIDESETVIRETYSETDKNDNSRYKMSSSFLGSQKNVSPGFIKIQQPV
Sbjct: 690 ALSRKVIGSSELSIDESETVIRETYSETDKNDNSRYKMSSSFLGSQKNVSPGFIKIQQPV 749
Query: 855 EEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETEPEMEPNP 914
EEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETEPEMEPNP
Sbjct: 750 EEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETEPEMEPNP 809
Query: 915 KSRPRAHTFPQQRYWPMYHPSMASTQSQTQTRTWSVERRRHPMDSYSPEGNSNEDV 970
KSRPRAHTFPQQRYWPMYHPSMASTQSQTQTRTWSVERRRHPMDSYSPEGNSNEDV
Sbjct: 810 KSRPRAHTFPQQRYWPMYHPSMASTQSQTQTRTWSVERRRHPMDSYSPEGNSNEDV 865
Score = 421 bits (1083), Expect = e-117
Identities = 209/211 (99%), Positives = 211/211 (100%)
Query: 1 MAQLERSAISGFSSKSRRNSFAYDVKREVYNEETFQQEHKRKASSSGNMNINITTFRHHV 60
MAQLERSAISGFSSKSRRNSFAYDVKREVYNEETFQQEHKRKASSSGNMNINITTFRHHV
Sbjct: 1 MAQLERSAISGFSSKSRRNSFAYDVKREVYNEETFQQEHKRKASSSGNMNINITTFRHHV 60
Query: 61 QCRCSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQL 120
QCRCSWHRFLRC+LTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQL
Sbjct: 61 QCRCSWHRFLRCMLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQL 120
Query: 121 IPPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSFVKN 180
IPPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSFVKN
Sbjct: 121 IPPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSFVKN 180
Query: 181 EFSAPSYLMGYNKSLSVVATTTFLTGIIQLI 211
EFSAPSYLMGYNKSLSVVATTTFLTGIIQ+I
Sbjct: 181 EFSAPSYLMGYNKSLSVVATTTFLTGIIQII 211
>gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo
sapiens]
Length = 759
Score = 373 bits (957), Expect = e-103
Identities = 241/787 (30%), Positives = 413/787 (52%), Gaps = 76/787 (9%)
Query: 22 AYDVKREVYNEET--FQQEHKRKASSSGNMNINITTFRHHVQCRCSWHRFLRCVLTIFPF 79
A D++R Y+ E QEH + G+ T + +CS R +L P
Sbjct: 21 AMDLRRRDYHMERPLLNQEHLEELGRWGSAP---RTHQWRTWLQCSRARAYALLLQHLPV 77
Query: 80 LEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIYVI 139
L W+ Y ++DWLLGDLL+G+SV ++Q+PQGL +LLA +PP+ Y++F IY +
Sbjct: 78 LVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAG--LPPVFGLYSSFYPVFIYFL 135
Query: 140 FGSCHQMSIGSFFLVSALLINVLK-VSPFNNGQLVMGSFVKNEFSAPSYLMGYNKSLSVV 198
FG+ +S+G+F ++S ++ +V + ++P Q + S + NE + + + V
Sbjct: 136 FGTSRHISVGTFAVMSVMVGSVTESLAP----QALNDSMI-NETARDA------ARVQVA 184
Query: 199 ATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIMLSQLTFIFGIMISFHAG 258
+T + L G+ Q+ +G++ GF+ TYL E + Y A A+ + +SQL ++FG+ +S H+G
Sbjct: 185 STLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSG 244
Query: 259 PISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISFNQY-PIEFPMELFLIIG 317
P+S Y ++ C LP++ +++ V L + K + Q P+ P EL +IG
Sbjct: 245 PLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIG 304
Query: 318 FTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGK 377
T I+ + + ++ IP + PV P+ L K++ AF++++V + I LGK
Sbjct: 305 ATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGK 364
Query: 378 KIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAG 437
A H Y V+SNQ+L+A+GL N++ F+ + +++R+++Q+ +GG Q A + +
Sbjct: 365 IFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSL 424
Query: 438 VMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWMMTFSSS 497
+LL++VK+G F+ LP AVLA II+ N+ L +S++ SLW+ ++ D +W++TF+++
Sbjct: 425 FILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTAT 484
Query: 498 IFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREIITIPGVKIFQ 557
I L LD+GL+++V+ + + VR+ +LGQ+P+T+IYR + +Y E + GVK+F+
Sbjct: 485 ILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFR 544
Query: 558 CCSSITFVNVYY----LKHKLLKEVDMV----KVPLKEEEIFSLFNSSDTNLQGGKICRC 609
+++ F N + LK + +VD + K LK++E L LQ + R
Sbjct: 545 SSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKL-----KQLQKEEKLR- 598
Query: 610 FCNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASEDQVPYTVSSVS 669
+ P+ +S+++ + E M ++ ED VSS
Sbjct: 599 -------------------KQAASPKGASVSINVNTSLEDMRSNNV--EDCKMMQVSS-G 636
Query: 670 QKNQGQQYEEVEEVWLPNNSSRNSSPGLPDVAESQGRRSLIPYSDASLLPSVHTIILDFS 729
K + E+ P+ S+ + GLP P H++ILD
Sbjct: 637 DKMEDATANGQEDSKAPDGSTLKAL-GLPQ-------------------PDFHSLILDLG 676
Query: 730 MVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGITKTQLFLSVH 789
+ +VD+ L L+ I + F+ + + +A CHS +V E FFDA ITK LF SVH
Sbjct: 677 ALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGHFFDASITKKHLFASVH 736
Query: 790 DAVLFAL 796
DAV FAL
Sbjct: 737 DAVTFAL 743
>gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo
sapiens]
Length = 738
Score = 372 bits (954), Expect = e-102
Identities = 240/785 (30%), Positives = 412/785 (52%), Gaps = 76/785 (9%)
Query: 24 DVKREVYNEET--FQQEHKRKASSSGNMNINITTFRHHVQCRCSWHRFLRCVLTIFPFLE 81
D++R Y+ E QEH + G+ T + +CS R +L P L
Sbjct: 2 DLRRRDYHMERPLLNQEHLEELGRWGSAP---RTHQWRTWLQCSRARAYALLLQHLPVLV 58
Query: 82 WMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIYVIFG 141
W+ Y ++DWLLGDLL+G+SV ++Q+PQGL +LLA +PP+ Y++F IY +FG
Sbjct: 59 WLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAG--LPPVFGLYSSFYPVFIYFLFG 116
Query: 142 SCHQMSIGSFFLVSALLINVLK-VSPFNNGQLVMGSFVKNEFSAPSYLMGYNKSLSVVAT 200
+ +S+G+F ++S ++ +V + ++P Q + S + NE + + + V +T
Sbjct: 117 TSRHISVGTFAVMSVMVGSVTESLAP----QALNDSMI-NETARDA------ARVQVAST 165
Query: 201 TTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIMLSQLTFIFGIMISFHAGPI 260
+ L G+ Q+ +G++ GF+ TYL E + Y A A+ + +SQL ++FG+ +S H+GP+
Sbjct: 166 LSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPL 225
Query: 261 SFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISFNQY-PIEFPMELFLIIGFT 319
S Y ++ C LP++ +++ V L + K + Q P+ P EL +IG T
Sbjct: 226 SLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGAT 285
Query: 320 VIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGKKI 379
I+ + + ++ IP + PV P+ L K++ AF++++V + I LGK
Sbjct: 286 GISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIF 345
Query: 380 ASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAGVM 439
A H Y V+SNQ+L+A+GL N++ F+ + +++R+++Q+ +GG Q A + + +
Sbjct: 346 ALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFI 405
Query: 440 LLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWMMTFSSSIF 499
LL++VK+G F+ LP AVLA II+ N+ L +S++ SLW+ ++ D +W++TF+++I
Sbjct: 406 LLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATIL 465
Query: 500 LGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREIITIPGVKIFQCC 559
L LD+GL+++V+ + + VR+ +LGQ+P+T+IYR + +Y E + GVK+F+
Sbjct: 466 LNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRSS 525
Query: 560 SSITFVNVYY----LKHKLLKEVDMV----KVPLKEEEIFSLFNSSDTNLQGGKICRCFC 611
+++ F N + LK + +VD + K LK++E L LQ + R
Sbjct: 526 ATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKL-----KQLQKEEKLR--- 577
Query: 612 NCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASEDQVPYTVSSVSQK 671
+ P+ +S+++ + E M ++ ED VSS K
Sbjct: 578 -----------------KQAASPKGASVSINVNTSLEDMRSNNV--EDCKMMQVSS-GDK 617
Query: 672 NQGQQYEEVEEVWLPNNSSRNSSPGLPDVAESQGRRSLIPYSDASLLPSVHTIILDFSMV 731
+ E+ P+ S+ + GLP P H++ILD +
Sbjct: 618 MEDATANGQEDSKAPDGSTLKAL-GLPQ-------------------PDFHSLILDLGAL 657
Query: 732 HYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGITKTQLFLSVHDA 791
+VD+ L L+ I + F+ + + +A CHS +V E FFDA ITK LF SVHDA
Sbjct: 658 SFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGHFFDASITKKHLFASVHDA 717
Query: 792 VLFAL 796
V FAL
Sbjct: 718 VTFAL 722
>gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo
sapiens]
Length = 758
Score = 371 bits (952), Expect = e-102
Identities = 239/787 (30%), Positives = 412/787 (52%), Gaps = 77/787 (9%)
Query: 22 AYDVKREVYNEET--FQQEHKRKASSSGNMNINITTFRHHVQCRCSWHRFLRCVLTIFPF 79
A D++R Y+ E QEH + G+ T + +CS R +L P
Sbjct: 21 AMDLRRRDYHMERPLLNQEHLEELGRWGSAP---RTHQWRTWLQCSRARAYALLLQHLPV 77
Query: 80 LEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIYVI 139
L W+ Y ++DWLLGDLL+G+SV ++Q+PQGL +LLA +PP+ Y++F IY +
Sbjct: 78 LVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAG--LPPVFGLYSSFYPVFIYFL 135
Query: 140 FGSCHQMSIGSFFLVSALLINVLK-VSPFNNGQLVMGSFVKNEFSAPSYLMGYNKSLSVV 198
FG+ +S+G+F ++S ++ +V + ++P Q + S + NE + + + V
Sbjct: 136 FGTSRHISVGTFAVMSVMVGSVTESLAP----QALNDSMI-NETARDA------ARVQVA 184
Query: 199 ATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIMLSQLTFIFGIMISFHAG 258
+T + L G+ Q+ +G++ GF+ TYL E + Y A A+ + +SQL ++FG+ +S H+G
Sbjct: 185 STLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSG 244
Query: 259 PISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISFNQY-PIEFPMELFLIIG 317
P+S Y ++ C LP++ +++ V L + K + Q P+ P EL +IG
Sbjct: 245 PLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIG 304
Query: 318 FTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGK 377
T I+ + + ++ IP + PV P+ L K++ AF++++V + I LGK
Sbjct: 305 ATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGK 364
Query: 378 KIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAG 437
A H Y V+SNQ+L+A+GL N++ F+ + +++R+++Q+ +GG Q A + +
Sbjct: 365 IFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSL 424
Query: 438 VMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWMMTFSSS 497
+LL++VK+G F+ LP AVLA II+ N+ L +S++ SLW+ ++ D +W++TF+++
Sbjct: 425 FILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTAT 484
Query: 498 IFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREIITIPGVKIFQ 557
I L LD+GL+++V+ + + VR+ +LGQ+P+T+IYR + +Y E + GVK+F+
Sbjct: 485 ILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFR 544
Query: 558 CCSSITFVNVYY----LKHKLLKEVDMV----KVPLKEEEIFSLFNSSDTNLQGGKICRC 609
+++ F N + LK + +VD + K LK++E L LQ + R
Sbjct: 545 SSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKL-----KQLQKEEKLR- 598
Query: 610 FCNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASEDQVPYTVSSVS 669
+ P+ +S+++ + E M ++ + VSS
Sbjct: 599 -------------------KQAASPKGASVSINVNTSLEDMRSNNV---EDCKMMVSS-G 635
Query: 670 QKNQGQQYEEVEEVWLPNNSSRNSSPGLPDVAESQGRRSLIPYSDASLLPSVHTIILDFS 729
K + E+ P+ S+ + GLP P H++ILD
Sbjct: 636 DKMEDATANGQEDSKAPDGSTLKAL-GLPQ-------------------PDFHSLILDLG 675
Query: 730 MVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGITKTQLFLSVH 789
+ +VD+ L L+ I + F+ + + +A CHS +V E FFDA ITK LF SVH
Sbjct: 676 ALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGHFFDASITKKHLFASVH 735
Query: 790 DAVLFAL 796
DAV FAL
Sbjct: 736 DAVTFAL 742
>gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo
sapiens]
Length = 740
Score = 349 bits (895), Expect = 8e-96
Identities = 232/787 (29%), Positives = 399/787 (50%), Gaps = 95/787 (12%)
Query: 22 AYDVKREVYNEET--FQQEHKRKASSSGNMNINITTFRHHVQCRCSWHRFLRCVLTIFPF 79
A D++R Y+ E QEH + G+ T + +CS R +L P
Sbjct: 21 AMDLRRRDYHMERPLLNQEHLEELGRWGSAP---RTHQWRTWLQCSRARAYALLLQHLPV 77
Query: 80 LEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIYVI 139
L W+ Y ++DWLLGDLL+G+SV ++Q+PQGL +LLA +PP+ Y++F IY +
Sbjct: 78 LVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAG--LPPVFGLYSSFYPVFIYFL 135
Query: 140 FGSCHQMSIGSFFLVSALLINVLK-VSPFNNGQLVMGSFVKNEFSAPSYLMGYNKSLSVV 198
FG+ +S+G+F ++S ++ +V + ++P Q + S + NE + + + V
Sbjct: 136 FGTSRHISVGTFAVMSVMVGSVTESLAP----QALNDSMI-NETARDA------ARVQVA 184
Query: 199 ATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIMLSQLTFIFGIMISFHAG 258
+T + L G+ Q+ +G++ GF+ TYL E + Y A A+ + +SQL ++FG+ +S H+G
Sbjct: 185 STLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSG 244
Query: 259 PISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISFNQY-PIEFPMELFLIIG 317
P+S Y ++ C LP++ +++ V L + K + Q P+ P EL +IG
Sbjct: 245 PLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIG 304
Query: 318 FTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGK 377
T I+ + + ++ IP + PV P+ L K++ AF++++V + I LGK
Sbjct: 305 ATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGK 364
Query: 378 KIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAG 437
A H Y V+SNQ+L+A+GL N++ F+ + +++R+++Q+ +GG Q A + +
Sbjct: 365 IFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSL 424
Query: 438 VMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWMMTFSSS 497
+LL++VK+G F+ LP AVLA II+ N+ L +S++ SLW+ ++ D +W++TF+++
Sbjct: 425 FILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTAT 484
Query: 498 IFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREIITIPGVKIFQ 557
I L LD+GL+++V+ + + VR+ +LGQ+P+T+IYR + +Y E + GVK+F+
Sbjct: 485 ILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFR 544
Query: 558 CCSSITFVNVYY----LKHKLLKEVDMV----KVPLKEEEIFSLFNSSDTNLQGGKICRC 609
+++ F N + LK + +VD + K LK++E L LQ
Sbjct: 545 SSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKL-----KQLQK------ 593
Query: 610 FCNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASEDQVPYTVSSVS 669
E KL +A + L C + Q +S D++ ++
Sbjct: 594 -------------------EEKLRKQAGPL-LSAC-----LAPQQVSSGDKMEDATANGQ 628
Query: 670 QKNQGQQYEEVEEVWLPNNSSRNSSPGLPDVAESQGRRSLIPYSDASLLPSVHTIILDFS 729
+ ++ ++ + LP PD + + D L S+ I DF
Sbjct: 629 EDSKAPDGSTLKALGLPQ----------PDFHSLILDLGALSFVDTVCLKSLKNIFHDF- 677
Query: 730 MVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGITKTQLFLSVH 789
+ + + +A CHS +V E FFDA ITK LF SVH
Sbjct: 678 --------------------REIEVEVYMAACHSPVVSQLEAGHFFDASITKKHLFASVH 717
Query: 790 DAVLFAL 796
DAV FAL
Sbjct: 718 DAVTFAL 724
>gi|4557535 solute carrier family 26, member 3 [Homo sapiens]
Length = 764
Score = 314 bits (805), Expect = 2e-85
Identities = 194/570 (34%), Positives = 308/570 (54%), Gaps = 32/570 (5%)
Query: 23 YDVKREVYNEETFQQEHKRKASSSGNMNINITTFRHHVQ--CRCSWHRFLRCVLTIFPFL 80
Y V R VY+ F++ HK+ TF H++ C CS + R VL++FP
Sbjct: 9 YIVARPVYSTNAFEENHKKTGRHH-------KTFLDHLKVCCSCSPQKAKRIVLSLFPIA 61
Query: 81 EWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIYVIF 140
W+ YRLK+WLL D+++GIS G+V V QGL +LL IPP+ YA+F ++IY+ F
Sbjct: 62 SWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVD--IPPVYGLYASFFPAIIYLFF 119
Query: 141 GSCHQMSIGSFFLVS-----ALLINVLKVSPFNNGQLVMGSFVKNEFSAPSYLMGYNKSL 195
G+ +S+G F ++S A+ V K P N + + N + S L +
Sbjct: 120 GTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLG---LPNNSNNSSLLDDERVRV 176
Query: 196 SVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIMLSQLTFIFGIMISF 255
+ A+ T L+GIIQL G+L +GF+ YL ES +S + A A+H+++SQL FIF + +
Sbjct: 177 AAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPS 236
Query: 256 HAGPISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISF-NQYPIEFPMELFL 314
H P+S F + + + K N ++ L V++ + I K I F ++ P+ P+E +
Sbjct: 237 HTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIM 296
Query: 315 IIGFTVIANKISMATETSQ-----TLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSS 369
TVIA +S + + DM P F P+TPD + F +++V+
Sbjct: 297 ----TVIAAGVSYGCDFKNRFKVAVVGDMNP-GFQPPITPDVETFQNTVGDCFGIAMVA- 350
Query: 370 FLLIFLGKKIASL-HNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQ 428
F + F + SL ++Y ++ NQ+LIA+GL N+V FR + A++R+ +Q+ +GG+
Sbjct: 351 FAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKT 410
Query: 429 QFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCA 488
Q A L+GA ++L++++ +G L +VLA + L N+ L + + LWR+D+YDC
Sbjct: 411 QIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCL 470
Query: 489 LWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREII 548
+W+MTF +I LGL +GL SV R+ K L I TNIY++ DY ++
Sbjct: 471 IWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMY 530
Query: 549 TIPGVKIFQCCSSITFVNVYYLKHKLLKEV 578
GVKIF+C S I F N+ + + KL+ V
Sbjct: 531 EPEGVKIFRCPSPIYFANIGFFRRKLIDAV 560
Score = 57.4 bits (137), Expect = 6e-08
Identities = 28/88 (31%), Positives = 47/88 (53%)
Query: 720 SVHTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGI 779
S+H++ILDFS V ++D + L+ I F + + I G + R +FFD +
Sbjct: 645 SLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEV 704
Query: 780 TKTQLFLSVHDAVLFALSRKVIGSSELS 807
+ FL++HDAVL L +K +S+ +
Sbjct: 705 KSSIFFLTIHDAVLHILMKKDYSTSKFN 732
>gi|16418413 solute carrier family 26, member 9 isoform a [Homo
sapiens]
Length = 791
Score = 308 bits (788), Expect = 2e-83
Identities = 226/778 (29%), Positives = 382/778 (49%), Gaps = 74/778 (9%)
Query: 63 RCSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIP 122
RCS + V + P L W+ Y++KD+++ DLL G+S G +QVPQG+ +LLA +P
Sbjct: 42 RCSSAKIKAVVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGGSIQVPQGMAFALLAN--LP 99
Query: 123 PLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINV-LKVSPFNNGQLVMGSFVKNE 181
+N Y++F + Y G HQM G+F ++S L+ N+ L+++P + Q+ + NE
Sbjct: 100 AVNGLYSSFFPLLTYFFLGGVHQMVPGTFAVISILVGNICLQLAPESKFQVFNNA--TNE 157
Query: 182 FSAPSYLMGYNKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIM 241
+ M + L V AT LT IIQ+ +G + GF+A YL ES + ++ A L I+
Sbjct: 158 SYVDTAAMEAER-LHVSATLACLTAIIQMGLGFMQFGFVAIYLSESFIRGFMTAAGLQIL 216
Query: 242 LSQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSIL------VFLTVVVALRINK 295
+S L +IFG+ I + GP S + I+ C LP N S++ FL +V L
Sbjct: 217 ISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPHTNIASLIFALISGAFLVLVKELNARY 276
Query: 296 CIRISFNQYPIEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLP 355
+I F PI P E+ +++ T I+ M + ++ I F PV+P S
Sbjct: 277 MHKIRF---PI--PTEMIVVVVATAISGGCKMPKKYHMQIVGEIQRGFPTPVSPVVSQWK 331
Query: 356 KIILQAFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAI 415
+I AFSL++VS + + +G+ +A+ H Y V+SNQ++IA+G N SFF+ V A+
Sbjct: 332 DMIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCAL 391
Query: 416 ARTIIQDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISN 475
+ T+ D +GG+ Q ASL + V+++ M+ +G + Y LP +VL +I N+ L+ +++
Sbjct: 392 SVTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTD 451
Query: 476 LPSLWRQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNT 535
LWR+ + DC +W+++F SS FL L G+ + V + + ++ L Q+ +T
Sbjct: 452 PYYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDT 511
Query: 536 NIYRSINDYREIITIPGVKIFQCCSSITFVNVYYLKHKLLKE--VDMVKVPLKEEEIFSL 593
+IY + Y I G+KI CS + F N + K++ + +D KV L +++
Sbjct: 512 DIYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLK- 570
Query: 594 FNSSDTNLQGGKICRCFCNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTS 653
++ + ++ P +L + S+
Sbjct: 571 --------------------------------KQEKRRMRPTQQRRSLFMKTKTVSLQEL 598
Query: 654 QTASEDQVPYTVSSVSQKNQGQQYEEVEEVWLPNNSS-RNSSPGLPDVAESQGRRSLIPY 712
Q E+ P ++ G + + P++SS S P P AE+ G S +
Sbjct: 599 QQDFENAPPTDPNNNQTPANGTSVSYI--TFSPDSSSPAQSEP--PASAEAPGEPSDML- 653
Query: 713 SDASLLPSV--HTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFE 770
AS+ P V HT+ILD S V +VD G+ L ++ + + + + + H+ +
Sbjct: 654 --ASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFLVNIHAQVYNDIS 711
Query: 771 RNDFFDAGITKTQ-LFLSVHDAVLFALS-----------RKVIGSSELSIDESETVIR 816
F+ G + + +F S+HDAVLFA + + G +ELS+ +SE IR
Sbjct: 712 HGGVFEDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQGAPGDAELSLYDSEEDIR 769
>gi|217272867 solute carrier family 26, member 9 isoform b [Homo
sapiens]
Length = 887
Score = 308 bits (788), Expect = 2e-83
Identities = 226/778 (29%), Positives = 382/778 (49%), Gaps = 74/778 (9%)
Query: 63 RCSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIP 122
RCS + V + P L W+ Y++KD+++ DLL G+S G +QVPQG+ +LLA +P
Sbjct: 42 RCSSAKIKAVVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGGSIQVPQGMAFALLAN--LP 99
Query: 123 PLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINV-LKVSPFNNGQLVMGSFVKNE 181
+N Y++F + Y G HQM G+F ++S L+ N+ L+++P + Q+ + NE
Sbjct: 100 AVNGLYSSFFPLLTYFFLGGVHQMVPGTFAVISILVGNICLQLAPESKFQVFNNA--TNE 157
Query: 182 FSAPSYLMGYNKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIM 241
+ M + L V AT LT IIQ+ +G + GF+A YL ES + ++ A L I+
Sbjct: 158 SYVDTAAMEAER-LHVSATLACLTAIIQMGLGFMQFGFVAIYLSESFIRGFMTAAGLQIL 216
Query: 242 LSQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSIL------VFLTVVVALRINK 295
+S L +IFG+ I + GP S + I+ C LP N S++ FL +V L
Sbjct: 217 ISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPHTNIASLIFALISGAFLVLVKELNARY 276
Query: 296 CIRISFNQYPIEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLP 355
+I F PI P E+ +++ T I+ M + ++ I F PV+P S
Sbjct: 277 MHKIRF---PI--PTEMIVVVVATAISGGCKMPKKYHMQIVGEIQRGFPTPVSPVVSQWK 331
Query: 356 KIILQAFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAI 415
+I AFSL++VS + + +G+ +A+ H Y V+SNQ++IA+G N SFF+ V A+
Sbjct: 332 DMIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCAL 391
Query: 416 ARTIIQDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISN 475
+ T+ D +GG+ Q ASL + V+++ M+ +G + Y LP +VL +I N+ L+ +++
Sbjct: 392 SVTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTD 451
Query: 476 LPSLWRQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNT 535
LWR+ + DC +W+++F SS FL L G+ + V + + ++ L Q+ +T
Sbjct: 452 PYYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDT 511
Query: 536 NIYRSINDYREIITIPGVKIFQCCSSITFVNVYYLKHKLLKE--VDMVKVPLKEEEIFSL 593
+IY + Y I G+KI CS + F N + K++ + +D KV L +++
Sbjct: 512 DIYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLK- 570
Query: 594 FNSSDTNLQGGKICRCFCNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTS 653
++ + ++ P +L + S+
Sbjct: 571 --------------------------------KQEKRRMRPTQQRRSLFMKTKTVSLQEL 598
Query: 654 QTASEDQVPYTVSSVSQKNQGQQYEEVEEVWLPNNSS-RNSSPGLPDVAESQGRRSLIPY 712
Q E+ P ++ G + + P++SS S P P AE+ G S +
Sbjct: 599 QQDFENAPPTDPNNNQTPANGTSVSYI--TFSPDSSSPAQSEP--PASAEAPGEPSDML- 653
Query: 713 SDASLLPSV--HTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFE 770
AS+ P V HT+ILD S V +VD G+ L ++ + + + + + H+ +
Sbjct: 654 --ASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFLVNIHAQVYNDIS 711
Query: 771 RNDFFDAGITKTQ-LFLSVHDAVLFALS-----------RKVIGSSELSIDESETVIR 816
F+ G + + +F S+HDAVLFA + + G +ELS+ +SE IR
Sbjct: 712 HGGVFEDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQGAPGDAELSLYDSEEDIR 769
>gi|4505697 pendrin [Homo sapiens]
Length = 780
Score = 292 bits (747), Expect = 1e-78
Identities = 210/808 (25%), Positives = 383/808 (47%), Gaps = 83/808 (10%)
Query: 20 SFAYDVKREVYNEETFQQEHKRKASSSGNMNINITTFRHHVQCRCSWHRFLRCVLTIFPF 79
S +Y V R VY+E FQQ+H+R+ + ++ C CS R + T+ P
Sbjct: 17 SCSYMVSRPVYSELAFQQQHERRLQERKTLRESLAKC-----CSCSRKRAFGVLKTLVPI 71
Query: 80 LEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIYVI 139
LEW+ YR+K+WLL D+++G+S GLV QG+ +LLA +P Y+AF + Y I
Sbjct: 72 LEWLPKYRVKEWLLSDVISGVSTGLVATLQGMAYALLAA--VPVGYGLYSAFFPILTYFI 129
Query: 140 FGSCHQMSIGSFFLVSALLINV-LKVSP-------FNNGQLVMGSFVKNEFSAPSYLMGY 191
FG+ +S+G F +VS ++ +V L ++P +NG ++ + + + ++
Sbjct: 130 FGTSRHISVGPFPVVSLMVGSVVLSMAPDEHFLVSSSNGTVLNTTMIDTAARDTARVL-- 187
Query: 192 NKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIMLSQLTFIFGI 251
+ + T L GIIQLI G L +GFI YL + + + A A +++SQL + +
Sbjct: 188 -----IASALTLLVGIIQLIFGGLQIGFIVRYLADPLVGGFTTAAAFQVLVSQLKIVLNV 242
Query: 252 MISFHAGPISFFYDIINYCVALPKANSTSILV-FLTVVVALRINKCIRISFNQYPIEFPM 310
+ G +S Y ++ + N LT+VV + + + ++ P+ P+
Sbjct: 243 STKNYNGVLSIIYTLVEIFQNIGDTNLADFTAGLLTIVVCMAVKELNDRFRHKIPVPIPI 302
Query: 311 ELFLIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSF 370
E+ + I T I+ ++ + ++ IP FL P P SL +++ +FS+++V+
Sbjct: 303 EVIVTIIATAISYGANLEKNYNAGIVKSIPRGFLPPELPPVSLFSEMLAASFSIAVVAYA 362
Query: 371 LLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQF 430
+ + +GK A+ ++Y+++ NQ+ IA G+ N+ S FF V T A++RT +Q+ +GG+ Q
Sbjct: 363 IAVSVGKVYATKYDYTIDGNQEFIAFGISNIFSGFFSCFVATTALSRTAVQESTGGKTQV 422
Query: 431 ASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALW 490
A ++ A ++++ ++ +G L +VLA ++++N+ + ++P LWRQ++ D +W
Sbjct: 423 AGIISAAIVMIAILALGKLLEPLQKSVLAAVVIANLKGMFMQLCDIPRLWRQNKIDAVIW 482
Query: 491 MMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREIITI 550
+ T SI LGLD+GL+ ++ F + TV +L Q P+ N SI
Sbjct: 483 VFTCIVSIILGLDLGLLAGLI--FGLLTV-------VLRVQFPSWNGLGSI--------- 524
Query: 551 PGVKIFQCCSSITFVNVYYLKHKLLKEVDMVKVPLKEEEIFSLFNSSDTNLQGGKIC-RC 609
P I++ + +K ++E VK+ IF N+ G K C +
Sbjct: 525 PSTDIYKSTKN----------YKNIEEPQGVKILRFSSPIFY------GNVDGFKKCIKS 568
Query: 610 FCNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASEDQVPYTVSSVS 669
D + + L R KL + + VS+ +
Sbjct: 569 TVGFDAIRVYNKRLKALRKIQKLIKSGQL---------------RATKNGIISDAVSTNN 613
Query: 670 QKNQGQQYEEVEEVWLPNNSSRNSSPGLPDVAESQGRRSLIPYSDASLLPSVHTIILDFS 729
+ E++EE+ +P ++ S +P +H+++LD
Sbjct: 614 AFEPDEDIEDLEELDIPTK----------EIEIQVDWNSELPVKVNVPKVPIHSLVLDCG 663
Query: 730 MVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGITKTQLFLSVH 789
+ ++D G+ LR I FQ ++ + A ++ E+ FFD I K FL+VH
Sbjct: 664 AISFLDVVGVRSLRVIVKEFQRIDVNVYFASLQDYVIEKLEQCGFFDDNIRKDTFFLTVH 723
Query: 790 DAVLFALSRKVIGSSELSIDESETVIRE 817
DA+L+ ++ + SI E+ T+I++
Sbjct: 724 DAILYLQNQVKSQEGQGSILETITLIQD 751
>gi|45827800 prestin isoform b [Homo sapiens]
Length = 685
Score = 282 bits (722), Expect = 9e-76
Identities = 158/505 (31%), Positives = 274/505 (54%), Gaps = 10/505 (1%)
Query: 64 CSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPP 123
C+ + + P +W+ Y+ K+++LGDL++GIS G++Q+PQGL ++LA +PP
Sbjct: 52 CTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAA--VPP 109
Query: 124 LNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSF-VKNEF 182
+ Y++F ++Y G+ +SIG F ++S L+I + V + ++ G N
Sbjct: 110 IFGLYSSFYPVIMYCFLGTSRHISIGPFAVIS-LMIGGVAVRLVPDDIVIPGGVNATNGT 168
Query: 183 SAPSYLMGYNKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIML 242
A L + V + T L+GIIQ +GV GF+A YL E + + A A+H+
Sbjct: 169 EARDALR-----VKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFT 223
Query: 243 SQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISFN 302
S L ++FG+ ++G S Y + + N S+ V L V L K F
Sbjct: 224 SMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFK 283
Query: 303 Q-YPIEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQA 361
+ P P+E F ++ T I+ ++ + ++ +P L P PD SL + + A
Sbjct: 284 EKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDA 343
Query: 362 FSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQ 421
++++V + I + K +A+ H Y V+ NQ+LIA+GLCN + S F++ + +++R+++Q
Sbjct: 344 IAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQ 403
Query: 422 DKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWR 481
+ +GG+ Q A + + ++LL+++ G F +LP AVL+ I++ N+ S+LP WR
Sbjct: 404 EGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWR 463
Query: 482 QDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSI 541
+ + +W+ TF SS+FLGLD GLI +V+ A R+ +LG++P T++Y I
Sbjct: 464 TSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDI 523
Query: 542 NDYREIITIPGVKIFQCCSSITFVN 566
+ Y E+ IPG+KIFQ + I + N
Sbjct: 524 DAYEEVKEIPGIKIFQINAPIYYAN 548
Score = 43.5 bits (101), Expect = 0.001
Identities = 19/48 (39%), Positives = 31/48 (64%)
Query: 720 SVHTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVR 767
+VHT+ILDF+ V+++DS G+ L I + + I + +AGC + I R
Sbjct: 638 NVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAFIQR 685
>gi|39752683 prestin isoform a [Homo sapiens]
Length = 744
Score = 282 bits (722), Expect = 9e-76
Identities = 158/505 (31%), Positives = 274/505 (54%), Gaps = 10/505 (1%)
Query: 64 CSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPP 123
C+ + + P +W+ Y+ K+++LGDL++GIS G++Q+PQGL ++LA +PP
Sbjct: 52 CTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAA--VPP 109
Query: 124 LNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSF-VKNEF 182
+ Y++F ++Y G+ +SIG F ++S L+I + V + ++ G N
Sbjct: 110 IFGLYSSFYPVIMYCFLGTSRHISIGPFAVIS-LMIGGVAVRLVPDDIVIPGGVNATNGT 168
Query: 183 SAPSYLMGYNKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIML 242
A L + V + T L+GIIQ +GV GF+A YL E + + A A+H+
Sbjct: 169 EARDALR-----VKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFT 223
Query: 243 SQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISFN 302
S L ++FG+ ++G S Y + + N S+ V L V L K F
Sbjct: 224 SMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFK 283
Query: 303 Q-YPIEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQA 361
+ P P+E F ++ T I+ ++ + ++ +P L P PD SL + + A
Sbjct: 284 EKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDA 343
Query: 362 FSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQ 421
++++V + I + K +A+ H Y V+ NQ+LIA+GLCN + S F++ + +++R+++Q
Sbjct: 344 IAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQ 403
Query: 422 DKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWR 481
+ +GG+ Q A + + ++LL+++ G F +LP AVL+ I++ N+ S+LP WR
Sbjct: 404 EGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWR 463
Query: 482 QDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSI 541
+ + +W+ TF SS+FLGLD GLI +V+ A R+ +LG++P T++Y I
Sbjct: 464 TSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDI 523
Query: 542 NDYREIITIPGVKIFQCCSSITFVN 566
+ Y E+ IPG+KIFQ + I + N
Sbjct: 524 DAYEEVKEIPGIKIFQINAPIYYAN 548
Score = 67.8 bits (164), Expect = 5e-11
Identities = 34/93 (36%), Positives = 53/93 (56%)
Query: 720 SVHTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGI 779
+VHT+ILDF+ V+++DS G+ L I + + I + +AGC + +V RN FF+
Sbjct: 638 NVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPA 697
Query: 780 TKTQLFLSVHDAVLFALSRKVIGSSELSIDESE 812
LF S+HDAVL + R+ + E S S+
Sbjct: 698 LWELLFHSIHDAVLGSQLREALAEQEASAPPSQ 730
>gi|100913030 solute carrier family 26 member 2 [Homo sapiens]
Length = 739
Score = 253 bits (647), Expect = 5e-67
Identities = 145/534 (27%), Positives = 279/534 (52%), Gaps = 27/534 (5%)
Query: 62 CRCSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLI 121
C+CS + +L P L+W+ Y LK +LGD+++G+ VG++ VPQ + SLLA Q
Sbjct: 78 CQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQ-- 135
Query: 122 PPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSFVKNE 181
P+ Y +F +S+IY + G+ +S+G F ++ ++ + + +L + N
Sbjct: 136 EPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETV------DRELQKAGY-DNA 188
Query: 182 FSAPSYLMGYNKS-----------------LSVVATTTFLTGIIQLIMGVLGLGFIATYL 224
SAPS M N S + V +T TF+ G+ Q+ MG +GF++ YL
Sbjct: 189 HSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYL 248
Query: 225 PESAMSAYLAAVALHIMLSQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSILVF 284
++ +S ++ + I+ SQ ++ G+ + G S I+ + K N ++
Sbjct: 249 SDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKTNLCDLITS 308
Query: 285 LTVVVALRINKCIRISF-NQYPIEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSF 343
L ++ L K + F ++ P+EL +++ T+ ++ + + ++ IP F
Sbjct: 309 LLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSSIAGHIPTGF 368
Query: 344 LLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVS 403
+ P P+++L+P + + A ++S++ + + L + A H Y+V +NQ++ AIG CN++
Sbjct: 369 MPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIP 428
Query: 404 SFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIIL 463
SFF + A+A+T++++ +G Q + +V A V+LL+++ + FY+L +VL I +
Sbjct: 429 SFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITI 488
Query: 464 SNVIPYLETISNLPSLWRQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHR 523
N+ L +LP +W + D +W +T SS L +IGL++ V + F +R+ +
Sbjct: 489 VNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQK 548
Query: 524 AKILLLGQIPNTNIYRSINDYREIITIPGVKIFQCCSSITFVNVYYLKHKLLKE 577
K LLG + + ++ S++ Y+ + PG+KIF+ + + ++N K L K+
Sbjct: 549 PKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFKSALYKQ 602
Score = 42.0 bits (97), Expect = 0.003
Identities = 22/75 (29%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
Query: 721 VHTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGIT 780
+HTI++D S + ++D+ G+ L+++ ++ I +L+A C+ + VR N +
Sbjct: 646 LHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPT-VRDSLTNGEYCKKEE 704
Query: 781 KTQLFLSVHDAVLFA 795
+ LF SV++A+ FA
Sbjct: 705 ENLLFYSVYEAMAFA 719
>gi|45827802 prestin isoform c [Homo sapiens]
Length = 516
Score = 248 bits (632), Expect = 3e-65
Identities = 141/460 (30%), Positives = 247/460 (53%), Gaps = 10/460 (2%)
Query: 64 CSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPP 123
C+ + + P +W+ Y+ K+++LGDL++GIS G++Q+PQGL ++LA +PP
Sbjct: 52 CTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAA--VPP 109
Query: 124 LNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSF-VKNEF 182
+ Y++F ++Y G+ +SIG F ++S L+I + V + ++ G N
Sbjct: 110 IFGLYSSFYPVIMYCFLGTSRHISIGPFAVIS-LMIGGVAVRLVPDDIVIPGGVNATNGT 168
Query: 183 SAPSYLMGYNKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIML 242
A L + V + T L+GIIQ +GV GF+A YL E + + A A+H+
Sbjct: 169 EARDALR-----VKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFT 223
Query: 243 SQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISFN 302
S L ++FG+ ++G S Y + + N S+ V L V L K F
Sbjct: 224 SMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFK 283
Query: 303 Q-YPIEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQA 361
+ P P+E F ++ T I+ ++ + ++ +P L P PD SL + + A
Sbjct: 284 EKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDA 343
Query: 362 FSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQ 421
++++V + I + K +A+ H Y V+ NQ+LIA+GLCN + S F++ + +++R+++Q
Sbjct: 344 IAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQ 403
Query: 422 DKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWR 481
+ +GG+ Q A + + ++LL+++ G F +LP AVL+ I++ N+ S+LP WR
Sbjct: 404 EGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWR 463
Query: 482 QDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRS 521
+ + +W+ TF SS+FLGLD GLI +V+ A R+
Sbjct: 464 TSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRT 503
>gi|47131207 solute carrier family 26, member 1 isoform a [Homo
sapiens]
Length = 701
Score = 234 bits (596), Expect = 4e-61
Identities = 138/523 (26%), Positives = 265/523 (50%), Gaps = 29/523 (5%)
Query: 62 CRCSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLI 121
C CS V + P W+ YR +++L GD+++G+ +G++ VPQ + SLLA +
Sbjct: 39 CSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAG--L 96
Query: 122 PPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLK--------------VSPF 167
P+ Y +F +++IY + G+ +S+G F L+ ++ V+ + P
Sbjct: 97 QPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPG 156
Query: 168 NNGQLVMGSFVKNEFSAPSYLMGYNKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPES 227
N + GS + Y ++ V T +TG+ Q++MGVL LGF++ YL +
Sbjct: 157 ANSSTLNGSAAMLDCGRDCY------AIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQP 210
Query: 228 AMSAYLAAVALHIMLSQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSILVFLTV 287
+ + ++ I+ SQL + G+ I H GP ++ + L A ++ +T
Sbjct: 211 LLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMV---VLTWLSLLRGAGQANVCDVVTS 267
Query: 288 VVALRINKCIRISFNQYP----IEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSF 343
V L + + ++Y + P EL +I+ T++++ + ++ IP F
Sbjct: 268 TVCLAVLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGF 327
Query: 344 LLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVS 403
+ P P+ L+ ++ L A +L+LV++ I L + A H YSV +NQ+L+A+G CNV+
Sbjct: 328 MPPQVPEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLP 387
Query: 404 SFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIIL 463
+F + A+A+++++ +G R Q +S+V A V+LL+++ + F+ L +VLA +I+
Sbjct: 388 AFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIV 447
Query: 464 SNVIPYLETISNLPSLWRQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHR 523
++ L + +LP LWR D +W T ++ + + + GL+ V+ + R+ R
Sbjct: 448 VSLRGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQR 507
Query: 524 AKILLLGQIPNTNIYRSINDYREIITIPGVKIFQCCSSITFVN 566
+ LL +I +T Y ++ ++ PGV++F+ + + N
Sbjct: 508 PRTALLARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYAN 550
Score = 46.6 bits (109), Expect = 1e-04
Identities = 36/114 (31%), Positives = 58/114 (50%), Gaps = 9/114 (7%)
Query: 693 SSPGLPDVAESQGRRSLIPYSD-ASLLPSV---HTIILDFSMVHYVDSRGLVVLRQICNA 748
S G+ + +QG L P S A+L+P+ HT+++D + + ++D+ G+ L+ +
Sbjct: 578 SETGVGEGGPAQGE-DLGPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRD 636
Query: 749 FQNANILILIAGCHSSIVRAFERNDFFDAGITKT----QLFLSVHDAVLFALSR 798
+ I +L+A C + R F G T QLFLSVHDAV A +R
Sbjct: 637 YGALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTARAR 690
>gi|20336272 solute carrier family 26, member 1 isoform a [Homo
sapiens]
Length = 701
Score = 234 bits (596), Expect = 4e-61
Identities = 138/523 (26%), Positives = 265/523 (50%), Gaps = 29/523 (5%)
Query: 62 CRCSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLI 121
C CS V + P W+ YR +++L GD+++G+ +G++ VPQ + SLLA +
Sbjct: 39 CSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAG--L 96
Query: 122 PPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLK--------------VSPF 167
P+ Y +F +++IY + G+ +S+G F L+ ++ V+ + P
Sbjct: 97 QPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPG 156
Query: 168 NNGQLVMGSFVKNEFSAPSYLMGYNKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPES 227
N + GS + Y ++ V T +TG+ Q++MGVL LGF++ YL +
Sbjct: 157 ANSSTLNGSAAMLDCGRDCY------AIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQP 210
Query: 228 AMSAYLAAVALHIMLSQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSILVFLTV 287
+ + ++ I+ SQL + G+ I H GP ++ + L A ++ +T
Sbjct: 211 LLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMV---VLTWLSLLRGAGQANVCDVVTS 267
Query: 288 VVALRINKCIRISFNQYP----IEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSF 343
V L + + ++Y + P EL +I+ T++++ + ++ IP F
Sbjct: 268 TVCLAVLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGF 327
Query: 344 LLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVS 403
+ P P+ L+ ++ L A +L+LV++ I L + A H YSV +NQ+L+A+G CNV+
Sbjct: 328 MPPQVPEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLP 387
Query: 404 SFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIIL 463
+F + A+A+++++ +G R Q +S+V A V+LL+++ + F+ L +VLA +I+
Sbjct: 388 AFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIV 447
Query: 464 SNVIPYLETISNLPSLWRQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHR 523
++ L + +LP LWR D +W T ++ + + + GL+ V+ + R+ R
Sbjct: 448 VSLRGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQR 507
Query: 524 AKILLLGQIPNTNIYRSINDYREIITIPGVKIFQCCSSITFVN 566
+ LL +I +T Y ++ ++ PGV++F+ + + N
Sbjct: 508 PRTALLARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYAN 550
Score = 46.6 bits (109), Expect = 1e-04
Identities = 36/114 (31%), Positives = 58/114 (50%), Gaps = 9/114 (7%)
Query: 693 SSPGLPDVAESQGRRSLIPYSD-ASLLPSV---HTIILDFSMVHYVDSRGLVVLRQICNA 748
S G+ + +QG L P S A+L+P+ HT+++D + + ++D+ G+ L+ +
Sbjct: 578 SETGVGEGGPAQGE-DLGPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRD 636
Query: 749 FQNANILILIAGCHSSIVRAFERNDFFDAGITKT----QLFLSVHDAVLFALSR 798
+ I +L+A C + R F G T QLFLSVHDAV A +R
Sbjct: 637 YGALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTARAR 690
>gi|16306483 solute carrier family 26, member 7 isoform a [Homo
sapiens]
Length = 656
Score = 195 bits (495), Expect = 2e-49
Identities = 134/490 (27%), Positives = 231/490 (47%), Gaps = 8/490 (1%)
Query: 78 PFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIY 137
P L+W Y LK+ LL D ++GI + + QV QGL ++L+ + P+ Y + ++IY
Sbjct: 33 PILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSS--VHPVFGLYGSLFPAIIY 90
Query: 138 VIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSFVKNEFSAPSYLMGYNKSLSV 197
IFG H ++ G+F L S + N ++ N Q + + + M + + V
Sbjct: 91 AIFGMGHHVATGTFALTSLISANAVERIVPQNMQNLTTQSNTSVLGLSDFEM---QRIHV 147
Query: 198 VATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIMLSQLTFIFGIMISFHA 257
A +FL G+IQ+ M VL LG + E +SA A H++ SQ+ ++ G+ + + +
Sbjct: 148 AAAVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLGMKMPYIS 207
Query: 258 GPISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISFNQ-YPIEFPMELFLII 316
GP+ FFY + ++L+ L +V L + K + F + + P++L LII
Sbjct: 208 GPLGFFYIYAYVFENIKSVRLEALLLSLLSIVVLVLVKELNEQFKRKIKVVLPVDLVLII 267
Query: 317 GFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLG 376
+ +M ++ IP P P ++L +I +AF ++LV + L
Sbjct: 268 AASFACYCTNMENTYGLEVVGHIPQGIPSPRAPPMNILSAVITEAFGVALVGYVASLALA 327
Query: 377 KKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLVGA 436
+ A YS++ NQ+ +A GL N+VSSFF A+ RT +G + Q A L+
Sbjct: 328 QGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMGRTAGLYSTGAKTQVACLISC 387
Query: 437 GVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWMMTFSS 496
+L+++ +G Y LP VLA II+ + L +L W D+ D +W+ T+
Sbjct: 388 IFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIWVSTYVF 447
Query: 497 SIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREIITIPGVKIF 556
+I ++GL+ VV I R RA + + + + + T+ VKI
Sbjct: 448 TICFAANVGLLFGVVCTIAIVIGRFPRAMTVSIKNMKEMEF--KVKTEMDSETLQQVKII 505
Query: 557 QCCSSITFVN 566
+ + F+N
Sbjct: 506 SINNPLVFLN 515
>gi|20336282 solute carrier family 26, member 7 isoform b [Homo
sapiens]
Length = 663
Score = 195 bits (495), Expect = 2e-49
Identities = 134/490 (27%), Positives = 231/490 (47%), Gaps = 8/490 (1%)
Query: 78 PFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIY 137
P L+W Y LK+ LL D ++GI + + QV QGL ++L+ + P+ Y + ++IY
Sbjct: 33 PILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSS--VHPVFGLYGSLFPAIIY 90
Query: 138 VIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSFVKNEFSAPSYLMGYNKSLSV 197
IFG H ++ G+F L S + N ++ N Q + + + M + + V
Sbjct: 91 AIFGMGHHVATGTFALTSLISANAVERIVPQNMQNLTTQSNTSVLGLSDFEM---QRIHV 147
Query: 198 VATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIMLSQLTFIFGIMISFHA 257
A +FL G+IQ+ M VL LG + E +SA A H++ SQ+ ++ G+ + + +
Sbjct: 148 AAAVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLGMKMPYIS 207
Query: 258 GPISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISFNQ-YPIEFPMELFLII 316
GP+ FFY + ++L+ L +V L + K + F + + P++L LII
Sbjct: 208 GPLGFFYIYAYVFENIKSVRLEALLLSLLSIVVLVLVKELNEQFKRKIKVVLPVDLVLII 267
Query: 317 GFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLG 376
+ +M ++ IP P P ++L +I +AF ++LV + L
Sbjct: 268 AASFACYCTNMENTYGLEVVGHIPQGIPSPRAPPMNILSAVITEAFGVALVGYVASLALA 327
Query: 377 KKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLVGA 436
+ A YS++ NQ+ +A GL N+VSSFF A+ RT +G + Q A L+
Sbjct: 328 QGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMGRTAGLYSTGAKTQVACLISC 387
Query: 437 GVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWMMTFSS 496
+L+++ +G Y LP VLA II+ + L +L W D+ D +W+ T+
Sbjct: 388 IFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIWVSTYVF 447
Query: 497 SIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREIITIPGVKIF 556
+I ++GL+ VV I R RA + + + + + T+ VKI
Sbjct: 448 TICFAANVGLLFGVVCTIAIVIGRFPRAMTVSIKNMKEMEF--KVKTEMDSETLQQVKII 505
Query: 557 QCCSSITFVN 566
+ + F+N
Sbjct: 506 SINNPLVFLN 515
>gi|217272870 solute carrier family 26, member 9 isoform c [Homo
sapiens]
Length = 459
Score = 166 bits (421), Expect = 7e-41
Identities = 127/473 (26%), Positives = 225/473 (47%), Gaps = 57/473 (12%)
Query: 361 AFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTII 420
AFSL++VS + + +G+ +A+ H Y V+SNQ++IA+G N SFF+ V A++ T+
Sbjct: 5 AFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLA 64
Query: 421 QDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLW 480
D +GG+ Q ASL + V+++ M+ +G + Y LP +VL +I N+ L+ +++ LW
Sbjct: 65 VDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLW 124
Query: 481 RQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRS 540
R+ + DC +W+++F SS FL L G+ + V + + ++ L Q+ +T+IY +
Sbjct: 125 RKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVN 184
Query: 541 INDYREIITIPGVKIFQCCSSITFVNVYYLKHKLLKE--VDMVKVPLKEEEIFSLFNSSD 598
Y I G+KI CS + F N + K++ + +D KV L +++
Sbjct: 185 PKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLK------ 238
Query: 599 TNLQGGKICRCFCNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASE 658
++ + ++ P +L + S+ Q E
Sbjct: 239 ---------------------------KQEKRRMRPTQQRRSLFMKTKTVSLQELQQDFE 271
Query: 659 DQVPYTVSSVSQKNQGQQYEEVEEVWLPNNSS-RNSSPGLPDVAESQGRRSLIPYSDASL 717
+ P ++ G + + P++SS S P P AE+ G S + AS+
Sbjct: 272 NAPPTDPNNNQTPANGTSVSYI--TFSPDSSSPAQSEP--PASAEAPGEPSDML---ASV 324
Query: 718 LPSV--HTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFF 775
P V HT+ILD S V +VD G+ L ++ + + + + + H+ + F
Sbjct: 325 PPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVF 384
Query: 776 DAGITKTQ-LFLSVHDAVLFALS-----------RKVIGSSELSIDESETVIR 816
+ G + + +F S+HDAVLFA + + G +ELS+ +SE IR
Sbjct: 385 EDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQGAPGDAELSLYDSEEDIR 437
>gi|65506789 solute carrier family 26, member 10 [Homo sapiens]
Length = 563
Score = 157 bits (396), Expect = 6e-38
Identities = 110/389 (28%), Positives = 192/389 (49%), Gaps = 27/389 (6%)
Query: 110 GLTLSLLARQLIPPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNN 169
G+ +LLA +PP+ Y +F +IY + G+ +S G+F ++S
Sbjct: 41 GMAFALLAS--VPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILS-------------- 84
Query: 170 GQLVMGSFVKNEFSAP--SYLMGYNKS------LSVVATTTFLTGIIQLIMGVLGLGFIA 221
L+ GS V+ P L G K + V A F +G + L M VL LG ++
Sbjct: 85 --LMTGSAVERLVPEPLVGNLSGIEKEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLS 142
Query: 222 TYLPESAMSAYLAAVALHIMLSQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSI 281
T+L E + A + ALH++LSQL + G+ + G S F + + ALP+++ +
Sbjct: 143 TFLSEPVVKALTSGAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAEL 202
Query: 282 LVFLTVVVALRINKCIRISF-NQYPIEFPMELFLIIGFTVIANKISMATETSQTLIDMIP 340
+ + L K + + F ++ P P E+ L++ +V+ S+ T ++ ++P
Sbjct: 203 TISALSLALLVPVKELNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLP 262
Query: 341 YSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCN 400
F P+ P+ + LP+I+ + ++LVS + L A ++Y+++SNQ+ +A G N
Sbjct: 263 GGFPQPLLPNLAELPRILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASN 322
Query: 401 VVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAG 460
++SS F + +A T + +GG+ Q A L V+L +++ +G FFY LP AVLA
Sbjct: 323 LISSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLAC 382
Query: 461 IILSNVIPYLETISNLPSLWRQDQYDCAL 489
I +S++ + LP LW + D L
Sbjct: 383 INISSMRQVFCQMQELPQLWHISRVDFLL 411
Score = 47.0 bits (110), Expect = 9e-05
Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 5/91 (5%)
Query: 721 VHTIILDFSMVHYVDSRG----LVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFD 776
V ++LDFS V + D+ G + V ++ + ++A I +L+A C++ + R D
Sbjct: 464 VRVVVLDFSGVTFADAAGAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLD 523
Query: 777 AGITKTQLFLSVHDAVLFALSRKVIGSSELS 807
+T QLF+SV DA +AL + GSS S
Sbjct: 524 R-VTPDQLFVSVQDAAAYALGSLLRGSSTRS 553
>gi|85540447 solute carrier family 26, member 11 [Homo sapiens]
Length = 606
Score = 126 bits (316), Expect = 1e-28
Identities = 118/468 (25%), Positives = 201/468 (42%), Gaps = 74/468 (15%)
Query: 78 PFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIY 137
P L W+ Y L+ WL D +AG+SVGL +PQ L + +A +PP Y+AF +Y
Sbjct: 35 PILAWLPSYSLQ-WLKMDFVAGLSVGLTAIPQALAYAEVAG--LPPQYGLYSAFMGCFVY 91
Query: 138 VIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSFVKNEFSAPSYLMGYNKSLSV 197
G+ +++G ++S L+ SF F P+Y +
Sbjct: 92 FFLGTSRDVTLGPTAIMSLLV-----------------SFYT--FHEPAYAV-------- 124
Query: 198 VATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIMLSQLTFIFGIMISFHA 257
FL+G IQL MGVL LGF+ ++ + + +A A+ I Q+ + G+
Sbjct: 125 --LLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQNI--- 179
Query: 258 GPISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISFNQYPIEFPMELFLIIG 317
P FF + + + + + ++ L ++ L + K +R E P + L G
Sbjct: 180 -PRPFFLQVYHTFLRIAETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPEMPPGVRLSRG 238
Query: 318 FTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSL-------LPKIILQAFSLSLVSSF 370
A A S ++ YSF + F L LP + + FS++ +
Sbjct: 239 LVWAATTARNALVVS--FAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGT 296
Query: 371 LL-----------------------IFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFR 407
+ I + K AS +NY +++NQ+L+AIGL N++ S
Sbjct: 297 ISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVS 356
Query: 408 SCVFTGAIARTIIQDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVI 467
S TG+ RT + +SG LV ++LL + + FY +P + LA +I+ V
Sbjct: 357 SYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAVA 416
Query: 468 PYLETISNLPSLWRQDQYD----CALWMMTFSSSIFLGLDIGLIISVV 511
P +T +LWR + D C +++ F + G+ G ++S++
Sbjct: 417 PLFDT-KIFRTLWRVKRLDLLPLCVTFLLCF-WEVQYGILAGALVSLL 462
>gi|45827804 prestin isoform d [Homo sapiens]
Length = 335
Score = 122 bits (307), Expect = 1e-27
Identities = 80/287 (27%), Positives = 140/287 (48%), Gaps = 10/287 (3%)
Query: 64 CSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPP 123
C+ + + P +W+ Y+ K+++LGDL++GIS G++Q+PQGL ++LA +PP
Sbjct: 52 CTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAA--VPP 109
Query: 124 LNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSF-VKNEF 182
+ Y++F ++Y G+ +SIG F ++S L+I + V + ++ G N
Sbjct: 110 IFGLYSSFYPVIMYCFLGTSRHISIGPFAVIS-LMIGGVAVRLVPDDIVIPGGVNATNGT 168
Query: 183 SAPSYLMGYNKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIML 242
A L + V + T L+GIIQ +GV GF+A YL E + + A A+H+
Sbjct: 169 EARDALR-----VKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFT 223
Query: 243 SQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISFN 302
S L ++FG+ ++G S Y + + N S+ V L V L K F
Sbjct: 224 SMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFK 283
Query: 303 Q-YPIEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSFLLPVT 348
+ P P+E F ++ T I+ ++ + ++ +P F +T
Sbjct: 284 EKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGFHTEMT 330
>gi|20336274 solute carrier family 26, member 1 isoform b [Homo
sapiens]
Length = 224
Score = 65.5 bits (158), Expect = 2e-10
Identities = 42/166 (25%), Positives = 76/166 (45%), Gaps = 22/166 (13%)
Query: 62 CRCSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLI 121
C CS V + P W+ YR +++L GD+++G+ +G++ VPQ + SLLA +
Sbjct: 39 CSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAG--L 96
Query: 122 PPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLK--------------VSPF 167
P+ Y +F +++IY + G+ +S+G F L+ ++ V+ + P
Sbjct: 97 QPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPG 156
Query: 168 NNGQLVMGSFVKNEFSAPSYLMGYNKSLSVVATTTFLTGIIQLIMG 213
N + GS + Y ++ V T +TG+ Q G
Sbjct: 157 ANSSTLNGSAAMLDCGRDCY------AIRVATALTLMTGLYQTSWG 196
>gi|4505419 nucleolar protein 3 [Homo sapiens]
Length = 208
Score = 50.8 bits (120), Expect = 6e-06
Identities = 27/67 (40%), Positives = 39/67 (58%), Gaps = 6/67 (8%)
Query: 850 IQQPVEEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETEPE 909
+Q EE E +LE E+ +EA + + E EPE+EP+AE E + + E EP PE EP+
Sbjct: 145 VQSGTPEEPEPELEAEASKEA------EPEPEPEPELEPEAEAEPEPELEPEPDPEPEPD 198
Query: 910 MEPNPKS 916
E +S
Sbjct: 199 FEERDES 205
Score = 40.4 bits (93), Expect = 0.008
Identities = 16/39 (41%), Positives = 23/39 (58%)
Query: 887 EPKAETETKTQTEMEPQPETEPEMEPNPKSRPRAHTFPQ 925
EP+ E E + E EP+PE EPE+EP ++ P P+
Sbjct: 152 EPEPELEAEASKEAEPEPEPEPELEPEAEAEPEPELEPE 190
Score = 38.9 bits (89), Expect = 0.024
Identities = 18/45 (40%), Positives = 25/45 (55%)
Query: 881 ELEPEMEPKAETETKTQTEMEPQPETEPEMEPNPKSRPRAHTFPQ 925
E EPE+E +A E + + E EP+ E E E EP P+ P P+
Sbjct: 152 EPEPELEAEASKEAEPEPEPEPELEPEAEAEPEPELEPEPDPEPE 196
Score = 38.1 bits (87), Expect = 0.040
Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 865 ESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPET--EPEMEPNPKSRP 918
E + G + + ELE E +AE E + + E+EP+ E EPE+EP P P
Sbjct: 140 EGSEAVQSGTPEEPEPELEAEASKEAEPEPEPEPELEPEAEAEPEPELEPEPDPEP 195
Score = 31.6 bits (70), Expect = 3.8
Identities = 15/42 (35%), Positives = 19/42 (45%)
Query: 893 ETKTQTEMEPQPETEPEMEPNPKSRPRAHTFPQQRYWPMYHP 934
E + + E E E EPE EP P+ P A P+ P P
Sbjct: 152 EPEPELEAEASKEAEPEPEPEPELEPEAEAEPEPELEPEPDP 193
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 44.3 bits (103), Expect = 6e-04
Identities = 36/147 (24%), Positives = 69/147 (46%), Gaps = 50/147 (34%)
Query: 841 KNVSPGFIKIQQPVEEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEM 900
K++SPG E S LD+E ESE++ ++E EP+ EP A+ + ++Q ++
Sbjct: 440 KSLSPG-------KENVSALDMEKESEEKE--------EKESEPQPEPVAQPQPQSQPQL 484
Query: 901 EPQPETEPEMEPNPKSRP-----------------RAHTFPQQRYWPM------------ 931
+ Q +++P ++ P S+P + H P+++ +P+
Sbjct: 485 QLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEP 544
Query: 932 ---YHPSMASTQSQTQTRTWSVERRRH 955
HP ++S+T+TR+ S R R+
Sbjct: 545 VLTVHP---ESKSKTKTRSRSRGRARN 568
Score = 38.5 bits (88), Expect = 0.031
Identities = 38/133 (28%), Positives = 57/133 (42%), Gaps = 39/133 (29%)
Query: 810 ESETVIRETYSETDKNDNSRYKMSSSFLGSQKNVSPGFIKIQQPVEEESELDLELESEQE 869
E ET +RE+ +K +S+ + L +NV + Q V E + ++ SE E
Sbjct: 367 EEETEVRES----EKQQDSQPEEVMDVLEMVENVK--HVIADQEVMETNRVESVEPSENE 420
Query: 870 AGLGLDLDLDRELEPEME-----------------------PKAETETKTQTEMEPQPET 906
A +ELEPEME + E+E K + E EPQP
Sbjct: 421 AS--------KELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQP-- 470
Query: 907 EPEMEPNPKSRPR 919
EP +P P+S+P+
Sbjct: 471 EPVAQPQPQSQPQ 483
>gi|21361639 DIPB protein [Homo sapiens]
Length = 344
Score = 43.9 bits (102), Expect = 7e-04
Identities = 24/77 (31%), Positives = 41/77 (53%)
Query: 851 QQPVEEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETEPEM 910
++ E E E + E ESE E+ + D + E+E E E +AE + + + E E + ETE E
Sbjct: 102 EEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAES 161
Query: 911 EPNPKSRPRAHTFPQQR 927
E +P+ A +++
Sbjct: 162 EFDPEIEMEAERVAKRK 178
Score = 40.8 bits (94), Expect = 0.006
Identities = 22/83 (26%), Positives = 43/83 (51%)
Query: 848 IKIQQPVEEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETE 907
+K++Q E ESE E ESE+E+ + + + E E E + ++E +++ + E E + E E
Sbjct: 83 VKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAE 142
Query: 908 PEMEPNPKSRPRAHTFPQQRYWP 930
+ + +S T + + P
Sbjct: 143 EDNQEEGESEAEGETEAESEFDP 165
Score = 35.0 bits (79), Expect = 0.34
Identities = 20/62 (32%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Query: 855 EEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETEPEMEPNP 914
E E +++ E E E EA G + + + E E E E + E E++ +++ E + ++E EME
Sbjct: 80 EAEVKVEQEREIESEA--GEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137
Query: 915 KS 916
+S
Sbjct: 138 ES 139
>gi|83977459 pleckstrin homology-like domain, family A, member 1
[Homo sapiens]
Length = 401
Score = 43.9 bits (102), Expect = 7e-04
Identities = 16/53 (30%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
Query: 883 EPEMEPKAETETKTQTEMEPQPETEPEMEPNPKSRP-RAHTFPQQRYWPMYHP 934
+P+ +P+ + + + Q + +PQP+++P+ +P PK +P + H +P P HP
Sbjct: 310 QPQPQPQLQPQPQPQPQPQPQPQSQPQPQPQPKPQPQQLHPYPHPHPHPHSHP 362
Score = 41.2 bits (95), Expect = 0.005
Identities = 16/57 (28%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Query: 881 ELEPEMEPKAETETKTQTEMEPQPETEP---EMEPNPKSRPRAHTFPQQRYWPMYHP 934
+L+P+ +P+ + + + Q++ +PQP+ +P ++ P P P H+ P P HP
Sbjct: 316 QLQPQPQPQPQPQPQPQSQPQPQPQPKPQPQQLHPYPHPHPHPHSHPHSHPHPHPHP 372
Score = 36.2 bits (82), Expect = 0.15
Identities = 14/52 (26%), Positives = 32/52 (61%), Gaps = 3/52 (5%)
Query: 886 MEPKAETETKTQTEMEPQPETEPEMEPNPKSRPRAHTFPQ---QRYWPMYHP 934
++ + ++ + Q +++PQP+ +P+ +P P+S+P+ P+ Q+ P HP
Sbjct: 303 VQQQPPSQPQPQPQLQPQPQPQPQPQPQPQSQPQPQPQPKPQPQQLHPYPHP 354
Score = 32.0 bits (71), Expect = 2.9
Identities = 14/59 (23%), Positives = 23/59 (38%), Gaps = 7/59 (11%)
Query: 883 EPEMEPKAETETKTQTEM-------EPQPETEPEMEPNPKSRPRAHTFPQQRYWPMYHP 934
+P+ +P+ + + K Q + P P + P P+P P H P P P
Sbjct: 330 QPQSQPQPQPQPKPQPQQLHPYPHPHPHPHSHPHSHPHPHPHPHPHQIPHPHPQPHSQP 388
>gi|7706589 GNAS complex locus NESP55 [Homo sapiens]
Length = 245
Score = 43.1 bits (100), Expect = 0.001
Identities = 26/63 (41%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
Query: 856 EESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETEPEMEPNPK 915
E E DLEL + L + + D E E E E + E+ET +TE E P TEPE EP
Sbjct: 87 EHEEADLELSLPE--CLEYEEEFDYETESETESEIESETDFETEPETAPTTEPETEPEDD 144
Query: 916 SRP 918
P
Sbjct: 145 RGP 147
Score = 42.7 bits (99), Expect = 0.002
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 3/116 (2%)
Query: 856 EESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETEPEMEPNPK 915
EE++L+L L E D + + E E E+E + + ET+ +T +PETEPE + P
Sbjct: 89 EEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTEPETEPEDDRGPV 148
Query: 916 SRPRAHTFPQQRYWPMYHPSMASTQSQTQTRTWSVERRRHPM--DSYSPEGNSNED 969
P+ TF Q ++ + S + S + + P + PE D
Sbjct: 149 V-PKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEELKPEDKDPRD 203
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 42.7 bits (99), Expect = 0.002
Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Query: 840 QKNVSPGFIKIQQPVEEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTE 899
+K SP I+ ++ E+E E + ELE EQE + + DRE + E E + E E + Q E
Sbjct: 496 EKQPSPEEIR-EREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQRE 554
Query: 900 MEPQPETEPEME 911
ME + + E E E
Sbjct: 555 MEKERKQEKEKE 566
Score = 35.4 bits (80), Expect = 0.26
Identities = 20/61 (32%), Positives = 32/61 (52%)
Query: 851 QQPVEEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETEPEM 910
+Q E+E E D E + E+E L + + RE+E E + + E E + Q E E + + E
Sbjct: 524 EQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQ 583
Query: 911 E 911
E
Sbjct: 584 E 584
Score = 35.4 bits (80), Expect = 0.26
Identities = 20/57 (35%), Positives = 30/57 (52%)
Query: 855 EEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETEPEME 911
E + E + ELE EQE ++ + +E E E+E + E E + Q E + E E E E
Sbjct: 536 ERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKE 592
Score = 34.3 bits (77), Expect = 0.58
Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Query: 846 GFIKIQQPVEEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPE 905
G ++ Q EE E + E E E+E L+ + ++E E E E E + + + E+E + E
Sbjct: 493 GILEKQPSPEEIREREREKEREREK--ELEKEQEQEREKEREKDRERQQEKEKELEKEQE 550
Query: 906 TEPEMEPNPK 915
+ EME K
Sbjct: 551 KQREMEKERK 560
Score = 32.3 bits (72), Expect = 2.2
Identities = 34/144 (23%), Positives = 60/144 (41%), Gaps = 22/144 (15%)
Query: 849 KIQQPVEEESELDLELESEQEAGLGLDLD-LDREL---EPEMEP---KAETETKTQTEME 901
++++ E+E EL E E+E L + + L+ ++ EP +EP K E+E E E
Sbjct: 566 ELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEE 625
Query: 902 P----------QPETEP---EMEPNPKSRPRAHTFPQ--QRYWPMYHPSMASTQSQTQTR 946
P + E P E EP S+PR +++ P Q Q + +
Sbjct: 626 PVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQ 685
Query: 947 TWSVERRRHPMDSYSPEGNSNEDV 970
W ++++ + P S+ V
Sbjct: 686 QWQQQQQQGVLPQTVPSQPSSSTV 709
Score = 31.6 bits (70), Expect = 3.8
Identities = 17/62 (27%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
Query: 851 QQPVEEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETEPEM 910
++ +E+E E E+E E++ +L+ +E E E++ E E + + E E + + E ++
Sbjct: 542 EKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKE-REKLEEKI 600
Query: 911 EP 912
EP
Sbjct: 601 EP 602
Score = 31.6 bits (70), Expect = 3.8
Identities = 28/144 (19%), Positives = 50/144 (34%), Gaps = 11/144 (7%)
Query: 805 ELSIDESETVIRETYSETDKNDNSRYKMSSSFLGSQKNVSPGFIKIQQPVEEESELDLEL 864
E +++ + E + N + S K P F + E+ +
Sbjct: 586 ECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVH 645
Query: 865 ESEQEAGL--------GLDLDLDRELEPEMEPKAETETKTQTEMEPQPETEPEMEPNPKS 916
E+E E+G G + L P + + E + Q + + Q P+ P S
Sbjct: 646 ETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVP---S 702
Query: 917 RPRAHTFPQQRYWPMYHPSMASTQ 940
+P + T P + P+Y P Q
Sbjct: 703 QPSSSTVPPPPHRPLYQPMQPHPQ 726
>gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4
[Homo sapiens]
Length = 818
Score = 42.0 bits (97), Expect = 0.003
Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
Query: 879 DRELEPEMEPKAETETKTQ----TEMEPQPETEPEMEPNPKSRPRAHTFPQQRYWPMYH- 933
D +++P+++ +A+T+T + + + QP+ + E EP + +P+ HT Q P H
Sbjct: 310 DTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHP 369
Query: 934 PSMASTQSQTQT 945
P+ S Q QT
Sbjct: 370 PAQVSVQPPEQT 381
Score = 32.3 bits (72), Expect = 2.2
Identities = 14/50 (28%), Positives = 28/50 (56%), Gaps = 2/50 (4%)
Query: 878 LDRELEPEMEPKAETETKTQTEMEPQ--PETEPEMEPNPKSRPRAHTFPQ 925
L +E EP+ + + + T+ Q ++PQ P + ++P ++ + HT PQ
Sbjct: 341 LQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQ 390
Score = 32.0 bits (71), Expect = 2.9
Identities = 44/172 (25%), Positives = 69/172 (40%), Gaps = 40/172 (23%)
Query: 819 YSETDKNDNSRYKMSSSFLGSQKNVSPGFIKIQQPVEEESELDLELESEQEAGLGLDLDL 878
++ + +N + + SSS ++K+ S + PVE++S D SE+ A +D
Sbjct: 150 FNLSGRNPQKQARTSSSTTPNRKDSSSQTM----PVEDKS--DPPEGSEEAAEPRMDTPE 203
Query: 879 DRELEP--------------EMEP--KAETETKTQTEMEPQPETEPEMEPNPKSRPRAH- 921
D++L P E EP +E K E E EP + K++P+A
Sbjct: 204 DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARM 263
Query: 922 TFPQQ-----------------RYWPMYHPSMASTQSQTQTRTWSVERRRHP 956
T P+Q R+ P A QSQTQ R S + + P
Sbjct: 264 TVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQP 315
Score = 30.8 bits (68), Expect = 6.4
Identities = 15/72 (20%), Positives = 34/72 (47%), Gaps = 1/72 (1%)
Query: 839 SQKNVSPGFIKIQQPVEEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQT 898
+Q SP + +QQ + + +L E E +++ + ++P+ P A+ +
Sbjct: 321 AQTQTSPEHLVLQQK-QVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPE 379
Query: 899 EMEPQPETEPEM 910
+ QP T+P++
Sbjct: 380 QTHEQPHTQPQV 391
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,540,475
Number of Sequences: 37866
Number of extensions: 1463543
Number of successful extensions: 7825
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 113
Number of HSP's that attempted gapping in prelim test: 6608
Number of HSP's gapped (non-prelim): 805
length of query: 970
length of database: 18,247,518
effective HSP length: 112
effective length of query: 858
effective length of database: 14,006,526
effective search space: 12017599308
effective search space used: 12017599308
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.